baber/WOPTO huggingface dataset:
Patent DE-69333180-T2 (DE)
Inventor: FROMMER WOLF-BERND
IPC: C12R1/19
Filed: 1993-06-22
Granted: 2004-05-27
Abstract: PCT No. PCT/EP93/01604 Sec. 371 Date Dec. 21, 1994 Sec. 102(e) Date Dec. 21, 1994 PCT Filed Jun. 22, 1993 PCT Pub. No. WO94/00574 PCT Pub. Date Jan. 6, 1994There are described DNA sequences, that contain the coding region of an oligosaccharide transporter, whose introduction in a plant genome modifies the formation and transfer of storage materials in transgenic plants, plasmids, bacteria and plants containing these DNA sequences, a process for the preparation and transformation of yeast strains, that makes possible the identification of the DNA sequences of the plant oligosaccharide transporter of the invention, as well as the use of DNA sequences of the invention.
Patent DE-69333632-T2 (DE)
Inventor: KLEIN PETER
IPC: A61P31/00
Filed: 1993-11-09
Granted: 2005-12-01
Abstract: Compounds and pharmaceutical compositions thereof comprise the general formula: <DF>(R)j - (core moiety), </DF> including resolved enantiomers and/or diastereomers, hydrates, salts, solvates and mixtures thereof, wherein j is an integer from one to three, the core moiety is non-cyclic or comprises at least one, five- to seven-membered ring structure, R may be selected from the group consisting of a hydrogen, halogen atom, hydroxyl, amino, substituted or unsubstituted benzyl, alkyl (C1-6) or alkenyl (C2-6) group, and at least one R has the general formula I: <CHEM> wherein n is an integer from four to eighteen; each R'1 and R'2 is independently a hydrogen atom, alkyl (C1-4) or alkenyl (C2-4) groups, the alkyl or alkenyl groups being preferably substituted by a halogen atom, hydroxyl, keto or dimethylamino group and/or may be interrupted by an oxygen atom; and each R'3 and R'4 is independently a hydrogen atom or methyl group. Preferably, n is an integer from six to ten, R'1 and R'2 are independently hydrogen atoms or methyl groups and R'3 and R'4 are hydrogen atoms. The compounds are useful in treating or preventing, for example, sepsis syndrome, hematopoietic or organ toxicity, baldness, hair loss or allopecia caused by cytotoxic therapies, and progression of an inflammatory or autoimmune disease.
Patent DE-69334102-T2 (DE)
Inventor: COHEN IRUN R
IPC: C07H11/00
Filed: 1993-11-09
Granted: 2007-10-18
Abstract: Substances comprising a N-sulfated or N-acetylated or non-sulfated N-acetylated 4-deoxy-4-en-iduronoglucosamine in substantially purified form, including compositions containing same and their uses are disclosed for the regulation of cytokine activity in a host. For instance, the secretion of Tumor Necrosis Factor Alpha (TNF- alpha ) can be either inhibited or augmented selectively by administration to the host of effective amounts of substances or their compositions comprising specific oligosaccharides in substantially purified form, in relation to the treatment or prevention of a medical condition which is selected from the group consisting of insulin-dependent diabetes mellitus, periodontal disease, inflammatory bowel disease, skin diseases, uveitis, rheumatic diseases, chronic inflammation, multiple sclerosis, lupus erythematosus, atherosclerosis, arthritis, vasculitis, allergy and neoplasia. The invention also relates to the initiation of a desirable immune system-related response by the host to the presence of activators, including pathogens, including viral infection, bacterial infection or fungal infection. <IMAGE>
Patent DE-69415455-T2 (DE)
Inventor: VAN DER TOL JOHANNES JACOBUS G
IPC: G02B6/14
Filed: 1994-09-09
Granted: 1999-06-10
Abstract: Integrated optical polarization converter provided with a channel-type waveguide (B) defined by a strip-type structure (S4) supported by a substrate (S) and consisting of a periodic concatenation of two different part strips having side walls which are at different angles with the plane of the substrate. Preferably, the two part strips then have as cross-sections either a trapezium (EFGH) with  DELTA 1,  DELTA 2  NOTEQUAL  0) and a rectangle (EFGH with  DELTA 1 =  DELTA 2 = 0), or both of them a right-angled trapezium with oblique sides situated opposite one another (EFGH with DELTA 1 = 0 and  DELTA 2  NOTEQUAL  0, and EFGH with  DELTA 1 NOTEQUAL  0 and  DELTA 2 = 0). Oblique and vertical side walls on such a strip-type structure supported by a substrate are fabricated, in the case of suitable crystal orientation, by means of two mutually complementary mask patterns, using etching steps, employing wet-chemical and dry etchants respectively. <IMAGE>
Patent DE-69422788-T2 (DE)
Inventor: BRETTON RANDOLPH H
IPC: A61M1/00
Filed: 1994-11-18
Granted: 2000-05-31
Abstract: A method and apparatus for destroying residual lens epithelial cells within a lens capsule of an eye. The apparatus includes a probe configured for insertion into the eye such that the probe is disposed either in the lens capsule or between the iris and the lens capsule. The probe is further configured to deliver energy therefrom to residual lens epithelial cells within the lens capsule in order to destroy them. The method includes the steps of inserting a probe constructed in accordance with the apparatus of present invention into the eye such that a distal end portion of the probe is disposed either within the lens capsule or between the iris and the lens capsule, delivering energy to the probe such that residual lens epithelial cells within the lens capsule are destroyed, ceasing the delivery of energy to the probe, and removing the probe from the eye.   <IMAGE>   <IMAGE>
Patent DE-69431978-T2 (DE)
Inventor: CHIANG JOHN YOUNG LING
IPC: C12Q1/6897
Filed: 1994-10-07
Granted: 2003-10-02
Abstract: A catalytically active, truncated human cholesterol 7 alpha -hydroxylase (CYP7) is provided. The truncated human CYP7 can be made recombinantly and thus recovered in relatively large amounts. Vectors and host cells for recombinant expression are provided, as well as an antibody which specifically recognizes an epitope of catalytically active, truncated human CYP7. Also provided is a method for screening a compound for its effect on expression of non-truncated human CYP7, and a method for screening a compound for its effect on non-truncated human CYP7 enzyme activity. <IMAGE>
Patent DE-69502640-T2 (DE)
Inventor: LOSIER THOMAS P
IPC: C07D201/12
Filed: 1995-02-23
Granted: 1998-09-17
Abstract: Disclosed is a process for recovering and purifying crude caprolactam from crude caprolactam-containing wastewaters consisting essentially of the steps:   (a) obtaining a wastewater stream containing crude caprolactam from at least one process which by-produces a crude caprolactam-containing wastewater stream selected from caprolactam polymerization, catalytic cracking of polymers and oligomers of caprolactam, and thermoplastic processing of polycaprolactam; (b) mixing the crude caprolactam-containing wastewater stream with between 0.01 to 5% by weight, based on the crude caprolactam in the wastewater stream, of an acid; (c) subjecting the mixture of crude caprolactam-containing wastewater stream and acid obtained according to step (b) to purification distillation at a temperature of between 100 to 180 DEG C and a pressure of between 50 to 3000 Pa; and (d) obtaining purified crude caprolactam as a distillate from step (c).
Patent DE-69502965-T2 (DE)
Inventor: BILLET GILLES
IPC: A61C13/30
Filed: 1995-11-21
Granted: 1999-03-18
Abstract: PCT No. PCT/FR95/01533 Sec. 371 Date May 9, 1997 Sec. 102(e) Date May 9, 1997 PCT Filed Nov. 21, 1995 PCT Pub. No. WO96/15731 PCT Pub. Date May 30, 1996A crown-and-root reconstruction assembly made of a composite materials with a modulus of elasticity varying along a gradient. The assembly comprises a physiological securing post (4) and a crown reconstruction base (1) made of partially or completely light-conducting material. The connection between the crown reconstruction base (1) and the post (4) is achieved by polymerising the material of the base under an isostatic charge. The forming process may be completed by manipulating the material with the fingers through a forming membrane (22) to prevent any gap developing at the interface (10) between the root (8) and the crown reconstruction base (1). A helical arrangement of the fibers (5) of the post (4) ensures that the modulus of elasticity is close to that of the natural dentine, regardless of the angle of incidence at the reconstruction is stressed.
Patent DE-69503319-T2 (DE)
Inventor: LOMBARDO ANTOINE
IPC: A47J27/09
Filed: 1995-05-23
Granted: 1998-12-24
Abstract: The safety element consists of a seal (20) fitted between a vessel and its lid, at least one section of which has an external recess (25) which allows the seal to deform under internal pressure, releasing excess pressure. A notch (26) on the inside of the seal opposite the recess increases the flexibility of the seal. The seal is of V-shaped cross-section with a base and two lips; the recess is made in the base and the notches in the two lips of the V. The seal can have a number of recesses spaced equally round its periphery. <IMAGE>
Patent DE-69525759-T2 (DE)
Inventor: THAGARD III GEORGE F
IPC: B29C67/24
Filed: 1995-10-19
Granted: 2002-10-24
Abstract: An asphaltic isocyanurate foam useful in roofing applications. The foam is made from asphalt having a penetration range of between approximately 5-25, a softening point of between approximately 120 DEG  F. and 200 DEG  F., and an asphaltene content of no more than about 30%. This asphalt is liquified and mixed with a mixture of polyols such as Voranol 270, Multranol 9138, and castor oil. Other chemicals, such as a surfactant, a viscosity reducer, and a flame retardant can also be included in this mixture. The mixture is then brought to a temperature of between approximately 140 DEG  F. and 220 DEG  F., mixed with water and a polyisocyanate in a molar ratio of polyisocyanate:polyol of between about 2.0:1 and about 2.5:1 and reacted to form an asphaltic isocyanurate foam.
Patent DE-69529823-T2 (DE)
Inventor: HALKIO JARI
IPC: H04L12/26
Filed: 1995-05-22
Granted: 2003-11-13
Abstract: PCT No. PCT/FI95/00278 Sec. 371 Date Nov. 25, 1996 Sec. 102(e) Date Nov. 25, 1996 PCT Filed May 22, 1995 PCT Pub. No. WO95/32569 PCT Pub. Date Nov. 30, 1995A method and equipment for monitoring the condition of an interconnecting interfaces, in which counters, specific to each interconnection interface are provided. Each counter is preset to a predetermined initial value, which is changed on the basis of the result of a monitoring cycle and at predetermined intervals. An alarm is given if the counter reaches or crosses a predetermined threshold value.
Patent DE-69530201-T2 (DE)
Inventor: VAARA TOMI
IPC: H04B7/26
Filed: 1995-06-12
Granted: 2003-12-11
Abstract: PCT No. PCT/FI95/00341 Sec. 371 Date Dec. 13, 1996 Sec. 102(e) Date Dec. 13, 1996 PCT Filed Jun. 12, 1995 PCT Pub. No. WO95/35006 PCT Pub. Date Dec. 21, 1995A handover in a mobile communication system in which a mobile station measures the level of the downlink signals of the neighboring cells of a serving cell, and transmits the measurement results to a fixed network which measures the receive level of the mobile station uplink signal at the serving cell. At least some of the cells of the mobile communication system are assigned as chains of two or more cells. The fixed network reacts to a sudden drop in the receive level of the mobile station uplink signal below a predetermined threshold level at the serving cell by carrying out a handover to a chained cell on the basis of one or more of the latest signal level measurements.
Patent DE-69531400-T2 (DE)
Inventor: BRUEGGER RENE
IPC: A61K39/395
Filed: 1995-09-07
Granted: 2004-05-27
Abstract: Immunoglobulin preparations, particularly liquid preparations of immunoglobulin G for intravenous infusion, are stabilized against dimer formation by the addition of one or more amphiphilic stabilizers. Preferred amphiphilic stabilizers are nicotinic acid derivatives, particularly nicotinamide, and naturally-occurring  alpha -amino acids having a lipophilic side chain, for example phenylalanine, proline, leucine and isoleucine.
Patent DE-69602517-T2 (DE)
Inventor: DYER JOHN COLLINS
IPC: C08L47/00
Filed: 1996-01-11
Granted: 1999-12-23
Abstract: Biodegradable and/or compostable polymers are made from isoprene, 2,3-dimethyl-1,3-butadiene or like conjugated dienes and a crosslinking agent having a cleavable linking group such as ethylene glycol dimethacrylate. These polymers can be used to make absorbent foams that are useful in absorbent articles such as diapers, as well as other biodegradable articles such as films, and latexes useful as binders and adhesives.
Patent DE-69603968-T2 (DE)
Inventor: SARTANI ABRAHAM
IPC: A61P9/10
Filed: 1996-06-28
Granted: 2000-04-06
Abstract: 1,4-Dihydropyridines have been found to counter several processes which play a role in the development of atherosclerotic vascular lesions, such as myocytes proliferation and migration, cholesterol metabolism in macrophages and oxidative modification of low density lipoproteins. They are therefore useful in the manufacture of medicaments for preventing, arresting and reversing atherosclerotic degradation in the arterial walls of humans. The preferred 1,4-dihydropyridines for this purpose are lercanidipine, (S)-lercanidipine and (R)-lercanidipine.
Patent DE-69606799-T2 (DE)
Inventor: ARMANDO MASSIMO
IPC: B65F3/08
Filed: 1996-05-31
Granted: 2000-08-17
Abstract: A device for tipping a refuse container over the body (2) of a refuse-collection vehicle (1) includes a guide structure (5) which can move between a position substantially parallel to a side wall (2a) of the vehicle (1) and a position inclined thereto. A carriage (9) is slidable along the guide structure (5) between a lowered position and a raised position upon actuation of first actuator means (13). A pair of arms (25) for picking up the container (C) are adapted to rotate relative to the carriage on actuation of second actuator means (23) which control the rotation of the arms (25) between a position in which they engage the container (C) and a position in which it is raised. A swingable member (18) is interposed between the guide structure (5) and the vehicle and articulated to the vehicle (1) and to the guide structure (5), a support rod (15) which can slide relative to the vehicle (1) in such a way that it can project in a direction transverse the side wall (2a) of the vehicle (1) is also articulated to the lower part of the guide structure (5).   <IMAGE>
Patent DE-69614782-T2 (DE)
Inventor: NISHIGUCHI MASAYUKI
IPC: G10L19/08
Filed: 1996-06-19
Granted: 2002-05-02
Abstract: An encoding unit 2 divides speech signals entering an input terminal 10 in terms of frames as units and encodes the divided signals on the frame basis to output encoding parameters such as line spectral pair (LSP) parameters, pitch, voiced (V)/ unvoiced (UV) or spectral amplitude Am. The modified encoding parameter calculating unit 3 interpolates the encoding parameters for calculating modified encoding parameters associated with desired time points. A decoding unit 6 synthesizes sine waves and the noise based upon the modified encoding parameters and outputs the synthesized speech signals at an output terminal 37. Speed control can be achieved easily at an arbitrary rate over a wide range with high sound quality with the phoneme and the pitch remaining unchanged. <IMAGE>
Patent DE-69619132-T2 (DE)
Inventor: LUDWIG JANOS
IPC: C07H21/02
Filed: 1996-11-14
Granted: 2002-07-18
Abstract: New chimeric oligomers having an RNA-cleavage activity, as well as their use for cleaving RNA-substrates in vitro and in vivo have been disclosed. The new chimeric oligomers contain an active centre, the building blocks of which are selected from nucleotides or/and nucleotide analogues, as well as flanking regions contributing to the formation of a specific hybridization of the oligomer with an RNA-substrate and containing at least one building block which is different from deoxyribonucleotides and ribonucleotides.
Patent DE-69628417-T2 (DE)
Inventor: UNGER JUERGEN
IPC: A61K9/08
Filed: 1996-03-08
Granted: 2004-03-18
Abstract: With the method of preparing a therapeutic agent for the treatment of multiple sclerosis, wherein human  beta  nerve growth factor (NGF) is brought into a pharmaceutically acceptable formulation for administering in a dose between 0.05  mu g and 5  mu g/kg body weight in 5 to 10 injections at an interval of 7 to 21 days, the regeneration of oligodendrocytes, especially for the treatment of multiple sclerosis, is improved and remyelination is accelerated.
Patent DE-69633059-T2 (DE)
Inventor: MURAOKA MASAMI
IPC: C07D471/04
Filed: 1996-05-28
Granted: 2005-08-18
Abstract: Naphthyridine derivative of the formula: <CHEM> wherein Ring A is substituted or unsubstituted pyridine, X is -N(R<2>)-CO- (R<2> is H, alkyl, substituted alkyl, etc.), Z is a direct bond, -NH-, C1-C2 alkylene, or -CH=CH-, Y is alkyl, substituted alkyl, aromatic group or substituted aromatic group, etc., B is alkyl, substituted alkyl, aromatic group or substituted aromatic group, or an acid addition salt thereof, these compounds having acyl-CoA: cholesterol acyl transferase inhibitory activity, and being useful as an agent for prophylaxis or treatment of hyperlipidemia, atherosclerosis, and related diseases thereof.
Patent DE-69636737-T2 (DE)
Inventor: WEISS ELISABETH
IPC: C07K14/705
Filed: 1996-06-20
Granted: 2007-10-18
Abstract: The invention concerns a new immunoregulatory protein LST-1, nucleic acd sequences coding for this protein, a process for the isolation of this protein, as well as its use for the production of a therapeutic agent. The DNA and protein sequences are shown in SEQ ID NO:1 to 4.
Patent DE-69701080-T2 (DE)
Inventor: VIOLI JEAN-CHARLES
IPC: A47J39/02
Filed: 1997-10-21
Granted: 2000-09-07
Abstract: The plate warmer comprises a tray (1) with twin bowls, one for hot food (3) and the other (30) for cold food. The tray base (6) is made of plastics. The hot food bowl (3) accepts a cover (2), and has an aluminium lining (19). The cover as an external envelope (22) made of plastics and lined with aluminium (23). An intermediate element (24) is placed in the centre of the cover, between outer envelope and lining. This element can be heated externally by a magnetic induction heater, and heat is transferred to the lining to be evenly spread over the inside of the cover. The cover lining makes contact (126) with the aluminium layer in the bowl.
Patent DE-69705417-T2 (DE)
Inventor: BODEREAU JEAN-PIERRE
IPC: B65G61/00
Filed: 1997-03-28
Granted: 2002-05-29
Abstract: A device for palletising stacked quire bundles (C), including means for gripping, transporting and depositing a bundle (C), said means being movable from a feed assembly (4) used for feeding the bundle (C) and consisting of the end of a carrying tray (5), to a pallet (6). Said gripping means consist of a frame (1) comprising a horizontal supporting surface enabling the bundle (C) to slide from the end of the carrying tray (5) of the feed assembly (4). The supporting surface may be removed from under the bundle (C) to enable same to be deposited on the pallet (6). The frame (1) comprises drive means for translating the surface along the side walls towards the rear surface of said frame (1). The device is useful for palletising bundles of quires.
Patent DE-69720996-T2 (DE)
Inventor: TJOENG S
IPC: A01N45/00
Filed: 1997-04-28
Granted: 2004-02-05
Abstract: The present invention discloses novel pharmaceutical compositions having steroid nitrate ester(ONO2) derivatives, and to their use treating undesired smooth muscle contractions and inflammatory diseases.
Patent DE-69721496-T2 (DE)
Inventor: GERRISH C
IPC: A61L15/28
Filed: 1997-02-14
Granted: 2004-04-08
Abstract: A polyvalent cation crosslinked pectin fiber composition is composed of a calcium sensitive low methoxyl pectin with a degree of esterification (DE) of less than 15% or calcium sensitive amidated pectin having a DE of less than 50% where the pectin is polyvalent cation crosslinkable and has an average molecular weight (MW) having an upper limit of 200,000 and a lower limit of 5000. This pectin is useful in making wound dressings for topical applications.
Patent DE-69724127-T2 (DE)
Inventor: SPERL GERHARD
IPC: A61K31/192
Filed: 1997-06-12
Granted: 2004-07-08
Abstract: Substituted benzylidene indenyl formamides, acetamides and propionamides are useful in the treatment of precancerous lesions and neoplasms.
Patent DE-69731778-T2 (DE)
Inventor: MILLER HOWARD
IPC: G11B33/00
Filed: 1997-12-17
Granted: 2005-11-24
Abstract: A device for applying a label to a disc includes a support member, preferably in the form of a plate for supporting a label on its upper surface, the plate having a central opening through which projects a disc positioning member, for example, in the form of a rod and a carriage member, preferably in the form of a plurality of bearings mounted on resilient arms. The bearings are adapted to move under pressure from above from a first position in which the bearings project upwardly through the opening to support the disc in spaced apart relationship to the label and to retain the label through its central aperture in concentric alignment with the disc to a second position in which the bearings are retracted below the upper surface of the plate for lowering the disc onto the label whereupon the label is adhered to the disc and is no longer retained by the bearings. Release of the downward pressure results in the labelled disc springing up for removal from the device leaving the bearings in their first position ready for repeated use. <IMAGE>
Patent DE-69806379-T2 (DE)
Inventor: NIELSEN MANN
IPC: A61F5/443
Filed: 1998-05-25
Granted: 2003-03-06
Abstract: The invention relates to an ostomy appliance comprising a body side member comprising an adhesive wafer or pad for securing the appliance to the user's skin, said wafer or pad having a hole for receiving a stoma, and an optionally separately exchangeable receiving member or bag secured to the body side ostomy member for receiving secretions from the ostomy, said ostomy appliance further comprising a sealing member disposed in the hole of the wafer or pad surrounding the stoma wherein the sealing member disposed in the hole of the wafer or pad surrounding the stoma, said sealing member having a hole for accommodating the stoma and said sealing member having balanced plastic and elastic properties allowing an adaptation of the hole of the ostomy appliance to a stoma by a temporary enlarging the hole by everting or rolling up the inner rim of the hole for accommodating the stoma. When the ostomy appliance of the invention has been placed over and around the stoma the adhesive sealing member may recover essentially to the original form to fit snugly to the stoma. Preferably at least the area of a release liner covering the separate sealing member is provided with a guide for adaptation of the hole of an ostomy appliance to the size of an ostomy, said guide being visible from the side of the release liner facing the sealing member.