baber/WOPTO huggingface dataset:
Patent UY-25441-A1 (UY)
Title: Procedimiento para la preparacion de formas galenicas de meloxicam para la aplicacion oral.
Inventor: DR THOMAS BOCK
IPC: A61K31/425
Filed: 1999-03-24
Abstract: Procedimiento para la preparación de una forma medicamentosa sólida de Meloxicam, que pertenece a los fármacos no esteroides anti-inflamatorios, aplicable por vía oral, que posee un corto tiempo de descomposición y de la que se libera y absorbe rápidamente el principio activo, para la terapia de dolores. Este procedimiento está caracterizado porque una sal de Meloxicam, eventualmente pulverizada, de una base inorgánica u orgánica, preferiblemente la sal de sodio, potasio o amonio, la sal de Meglumina, la sal Tris o la sal de un aminoácido de carácter básico, se mezcla íntimamente con coadyuvantes y/o sustancias de soporte pulverizados adecuados y, sin granulación del polvo antes del prensado, se prensa directamente en tabletas.
Patent UY-25663-A1 (UY)
Title: Procedimiento para preparar isoquinolinas
Inventor: BARBER CHRISTOPHER GORDEN
IPC: C07D401/12
Filed: 1999-08-16
Abstract: Se describen procedimientos para preparar compuestos de isoquinolinilguanidina de la formula (I), y sales de los mismos, como inhibidores de uroquinasas. La fórmula (I) donde G es N=C(NH)2 o NHC(=NH)NH2; R1 s H o halo; X es CO, CH2 o SO2; R2 es H, arilo, hetroarilo, X`es arileno, alquileno,etc Ejemplo: (a) 2-(((4-cloro-1-guanidino-7-isoquinolinil)sulfonil)amino)benzoato de terc-butilo (b) Clorhidrato del ácido 2-(((4-cloro-1-guanidino-7-isoquinolinil)sulfonil)benzoico
Patent UY-26493-A1 (UY)
Title: " forma de dosificación de fármaco en capas impulsada por hidrogel"
Inventor: CURATOLO WILLIAM JOHN
IPC: A61K9/22
Filed: 2000-12-20
Abstract: Una forma de dosificación de liberación controlada para sertralina tiene un núcleo que comprende una composición que contiene sertralina y una composición hinchable en agua, en donde la composición hinchable en agua está situada en una región separada dentro del núcleo. Un revestimiento en torno al núcleo es permeable al agua, insoluble en agua, y tiene al menos una abertura de suministro a través del mismo. En una realización, la forma de dosificación libera sertralina hacia el entorno de uso con una velocidad media de 6 a 10 % en peso por hora desde la segunda hasta la décima hora después de la introducción en un entorno de uso, y menos de aproximadamente 25% en peso durante las dos primeras horas y al menos 70% en peso al cabo de la décima hora, en donde los porcentajes corresponden a la masa de fármaco liberado desde el comprimido dividida por la masa total de fármaco originalmente presente en el comprimido. En otra realización, la forma de dosificación libera menos de aproximadamente 25% en peso de sertralina hacia el entorno de uso al cabo de la segunda hora después de la introducción de la forma de dosificación en el entorno de uso, y suministra al menos 25% en peso desde la octava hora hasta la vigesimocuarta.
Patent UY-27324-A1 (UY)
Title: Nuevas sales de napsilato i
Inventor: LYNNE TAYLOR
IPC: C07C309/35
Filed: 2002-06-07
Abstract: Novedosas sales napsilato de fórmula I, o solvatos de las mismas y estereoisómeros de las mismas, así como también un proceso para la preparación de los mismos, composiciones farmacéuticas que contienen la sal de napsilato terapéuticamente activa y el uso de los mencionados compuestos activos en tratamientos.
Patent UY-30156-A1 (UY)
Title: Uso de derivados de benzo-heteroarilsulfamida para el tratamiento de la migrana
Inventor: SMITH-SWINTOSKY VIRGINIA L
IPC: A61K31/18
Filed: 2007-02-14
Abstract: La presente invención se refiere a un método para el tratamiento onprevención de la migrana que comprende administrar a un sujeto que lo necesita una cantidad terapéuticamente eficaz de uno o más derivados novedosos de benzo-heteroarilsulfamida de fórmula (I) según lo definido en esta invención. La presente invención se refiere a un método para el tratamiento y/o prevención de la migrana, el cual incluye monoterapia y alternativamente, terapia conjunta con al menos un agente contra la migrana.
Patent UY-31121-A1 (UY)
Title: Antagonistas del receptor de urotensina ii
Inventor: GHOSH SHYMALAI
IPC: A61P1/18
Filed: 2008-06-05
Abstract: La invención se refiere a un compuesto de la Fórmula (I): y formas del mismo, en el cual A, B, E, G, X y L2 son como se definen en la presente y a su uso como antagonistas del receptor de urotensina II.
Patent AT-503323-A1 (AT)
Inventor: BACHER HELMUT
IPC: B29C48/05
Filed: 2005-01-18
Abstract: A strand shaping part for connecting an extruder ( 1 ) to a granulating system has a number of supply channels ( 8 ) that can be flow-connected to the outlet ( 5 ) of the extruder ( 1 ). These supply channels lead to gear pumps ( 21 ) which have a delivery behaviour that is as constant as possible and with which the flow of melt to channels ( 11 ) can be blocked during start up. A single channel ( 11 ) leads from each gear pump ( 21 ) to a strand die ( 9 ) that can be formed by holes of a perforated plate ( 10 ) which is connected to a perforated plate head ( 7 ). Several gear pumps ( 21 ) are driven by a common shaft ( 24 ). The method for starting a granulating system provided with a strand shaping part of the aforementioned type provides that the extruder ( 1 ) is first started until a sufficient pressure is built up at the inlet ( 27 ) of each gear pump ( 21 ). Once this pressure is reached, each gear pump ( 21 ) is started again. In an underwater granulating system, the granulating blades ( 12 ) are rotationally driven last (FIG. 1 ).
Patent DZ-1734-A1 (DZ)
Inventor: MILLWARD WILLIAM ANTHONY
IPC: F16L58/10
Filed: 1993-12-08
Granted: 2002-02-17
Abstract: PCT No. PCT/GB93/02483 Sec. 371 Date Aug. 17, 1994 Sec. 102(e) Date Aug. 17, 1994 PCT Filed Dec. 2, 1993 PCT Pub. No. WO94/13992 PCT Pub. Date Jun. 23, 1994A pipe and method of manufacture of the pipe are described. The pipe comprises a core of helically wound steel strip embedded in a plastics material matrix and lined with inner and outer linings of filament wound fiber reinforced plastics material.
Patent ES-177415-A1 (ES)
Title: Perfeccionamientos en los sistemas de mando centralizado del trafico de ferrocarriles
IPC: B61L7/08
Filed: 1947-03-29
Abstract: Perfeccionamientos en los sistemas de mando centralizado del tráfico de ferrocarriles, que, en un sistema de esta naturaleza, incluyen: un circuito de línea prolongado desde una oficina de control a un puesto de la playa; medios para suministrar energía al circuito de línea, con absoluta seguridad, montados en la oficina de control; en el puesto de la playa, un relevador transmisor de claves para, una vez excitado, aplicar una derivación a dicho circuito de línea; otro relevador transmisor de claves, en el puesto de la playa, para, una vez excitado, separar dicha derivación del circuito de línea; circuitos para excitar cada uno de dichos relevadores transmisores de claves, respectivamente, en relación alternada para períodos de tiempo largos y cortos seleccionados, para realizar la transmisión de una serie de signos de clave a la oficina de control, dicha serie constituida por períodos de "acoplado" y "no-acoplado" transmitidos en relación alternada y siendo cada uno de dichos períodos de una longitud seleccionada, y medios dependientes de las claves, en la oficina de control, para recibir dicha serie de signos de clave.
Patent ES-179326-A1 (ES)
Title: UN CIRCUITO PERFECCIONADO PARA RECEPTORES RADIOTELEFoNICOS Y SUS APLICACIONES
Filed: 1947-08-14
Abstract: Un circuito perfeccionado para receptores radiotelefónicos y sus aplicaciones caracterizado porque es aplicable a receptores en los cuales se quiere economizar una válvula ya que está constituido de modo que la primera válvula del circuito hace las funciones de amplificadora de radio frecuencia utilizando todos los electrodos de la válvula y además funciona como amplificadora de audio utilizando solamente su primera rejilla y su pantalla en conexión triodo obteniéndose de esta forma un coeficiente de amplificación de 15.
Patent ES-186104-A1 (ES)
Title: Un amplificador superregenerativo
Filed: 1948-11-27
Abstract: Un amplificador superregenerativo caracterizado por medios para cambiar la frecuencia funcional del circuito oscilatorio regenerativo durante una porción de cada periódo de extinción.
Patent ES-187221-A1 (ES)
Title: PERFECCIONAMIENTOS EN APARATOS PARA LA CARGA Y DESCARGA AUTOMáTICA DE VEHiCULOS
Filed: 1949-02-26
Abstract: Perfeccionamientos en aparatos para la carga y descarga automáticas de vehículos caracterizándose por la disposición de un chasis especial un receptáculo cualquiera pudiendo este chasis especial ser levantado del suelo por medio de un mecanismo accionado por el motor del camión automóvil o tractor disponiendo automáticamente este mismo mecanismo el chasis especial sobre unos largueros de perfil especial del camión o del remolque estando constituido el citado perfil por una combinación de inclinaciones diferentes efectuándose esta combinación de modo que no de lugar a pérdida alguna de sitio para el chasis especial cuando se encuentra sobre el camión o el remolque pudiendo el citado mecanismo desplazar el chasis especial a lo largo de los largueros de perfil especial dirigiendole y bloqueándole perfectamente sobre el camión o el remolque puediendo tener lugar esta operación en sentido contrario.
Patent ES-196354-A1 (ES)
Title: MEJORAS EN LA FABRICACIoN DE PIEDRAS HUECAS COMO CUERPOS DE RELLENO PARA TECHOS
Filed: 1951-01-31
Abstract: Mejoras en la fabricación de piedras huecas como cuerpos de relleno para techos en cuyos soportes se hallan perfiles ligeros de acero caracterizadas porque las paredes laterales del cuerpo de relleno están situadas oblicuamente para formar a pares un nervio en o uña que además en el extremo inferior poseen un espaldón o análogo cortado por debajo dirigido hacia abajo y en la prolongación del fondo tienen listones de pie o análogos para cubrir por encima la anchura de los nervios.
Patent ES-197496-A1 (ES)
Title: PROCEDIMIENTO PARA OBTENER IMáGENES FOTOGRáFICAS SOBRE TEJIDOS Y MATERIALES FLEXIBLES
Filed: 1951-04-11
Abstract: Procedimiento para obtener imágenes fotográficas sobre tejidos y materiales flexibles caracterizado porque las imágenes se obtienen por destrucción fotoquímica de compuestos diazoicos desarrollo ulterior en un baño de un copulante y eventualmente tratamientos de mejora con formol o sales metálicas.
Patent ES-197497-A1 (ES)
Title: PROCEDIMIENTO PARA ABRILLANTAR Y PULIMENTAR SIMULTáNEAMENTE OBJETOS DE COBRE Y SUS ALEACIONES
Filed: 1951-04-11
Abstract: Procedimiento para abrillantar y pulir simultáneamente objetos de cobre o sus aleaciones por ejemplo de latón caracterizado porque el objeto en tratamiento se sumerge en un bañO que contiene ácido nítrico y ácido crómico concentrados eventualmente en presencia de un poco de agua.
Patent ES-260087-A1 (ES)
Title: Improvements relating to cis-1,4-polybutadiene
IPC: C07C51/48
Filed: 1960-08-02
Abstract: Cis-1,4-polybutadiene of controlled molecular weight is obtained by polymerizing butadiene with a catalyst comprising a dialkyl aluminium monohalide, and a compound of a metal of Group VIII of the Periodic Table according to Mendel<\>aeeff, in the presence of a solvent mixture comprising at least one aromatic and at least one aliphatic hydrocarbon, and controlling the average molecular weight of the polymer by increasing the volume ratio between the aromatic and aliphatic hydrocarbons in the mixture. The aliphatic hydrocarbon may be butane, pentane, petroleum ether, heptane, or iso-octane. The aromatic hydrocarbon may be benzene, or toluene. The catalysts exemplified are diethyl aluminium chloride admixed with nickel or cobalt diacetylacetonate.
Patent ES-262720-A1 (ES)
IPC: B65H65/00
Filed: 1960-11-11
Abstract: Aparato para fijar automáticamente el extremo del hilo arrollado sobre una canilla u otro soporte de arrollamiento, por medio de un arrollamiento auxiliar, efectuado sobre el extremo de la canilla y a una cierta distancia del cuerpo de arrollamiento principal; caracterizado por la combinación de medios para formar el arrollamiento auxiliar en un plano inclinado respecto al eje de rotación de la canilla; medios para desviar luego este arrollamiento auxiliar a un plano perpendicular el eje de la canilla y para levantar, por lo menos durante una rotación de la canilla, el arrollamiento auxiliar en un punto que gira alrededor de la canilla; y medios para insertar el hilo que va llegando, debajo de la parte levantada del arrollamiento auxiliar, de manera que este hilo que llega quede inmediatamente cubierto por la parte levantada del arrollamiento auxiliar, que se aplica de nuevo sobre la canilla.
Patent ES-272078-A1 (ES)
Title: Polypropylene heat stabilized with interpolyamide
IPC: C08L23/12
Filed: 1961-11-16
Abstract: Polypropylene compositions of improved thermal stability and dyeability, comprise a minor proportion, e.g. 5 to 15%, of an interpolyamide obtained by the condensation of a mixture of hexamethylenediammonium adipate and hexamethylenediammonium sebacate. Specification 873,830 is referred to.
Patent ES-331160-A1 (ES)
Title: Large fast nuclear reactor
IPC: G21C1/02
Filed: 1966-09-13
Abstract: In a sodium-cooled, fast breeder reactor having a core size of at least 800 litres, the core includes a thorium central zone which induces a negative, or low positive, coolant void coefficient. The central zone 10 comprises uranium-233, thorium-232, surrounded by zone 11 formed of uraniun-238 and plutonium. Blankets 12, 13 and 14 contain depleted uranium. The solid fuel material may comprise metals, oxides and carbides as well as nitrides, sulphides and mixtures of ceramics and metals.
Patent ES-333467-A1 (ES)
Title: Method and apparatus for producing high-speed translational movement
IPC: G01T5/06
Filed: 1966-11-17
Abstract: In a bubble chamber, the expansion piston is reciprocable by a second nitrogen gas operated piston coupled thereto. Movement of the two piston assembly is controlled by a gas operated retaining latch and a gas pressurized plunger which compensates for energy loss during reciprocation. Programming is effected by electrically operated valves in the gas system controlled by a pulse generator and time base through bi-stable devices. In a modification, elimination of mechanical shocks in the system during repeated reciprocation, is effected by a hydraulic energy accumulator associated with the two-piston assembly.
Patent ES-339246-A1 (ES)
Title: Means for controlling casting
IPC: B22D18/04
Filed: 1967-04-13
Abstract: Molten metal 22, from a ladle 20 placed in a pressure vessel 10, is forced up a tube 24 into a mould 28 by air from a conduit 18, the air flow being maintained by valves 52, 54 operated by controllers 62, 64 which are self regulating according to the difference in air pressure across an orifice 42 in the conduit. First, a graphite stopper 32 is lowered to close the mould ingate 38 and simultaneously to operate a switch to cause a twoway valve 98 to direct air (from the main or an auxiliary supply) to open a main valve 56 in the air conduit 18 and close an exhaust valve 60. The switch also operates a two-way valve 76 to supply the air to the controller 62 also, so that the latter allows the air to pass to the valve 52 to open it and permit and maintain a constant main air flow to the pressure vessel 10. The resulting flow of metal into the mould 28 raises the stopper to operate a switch to both cause the valve 76 to close the valve 52 and cause another two-way valve 88 to open the valve 54. The latter permits a lower rate of air flow to the vessel 10 until the mould 28 is filled. The final rise of the stopper 32 actuates a switch to cause the valve 88 to close the valve 54. The stopper is then lowered to close the ingate 38 and simultaneously operate the valve 98 to cause the main valve 56 to close and the valve 60 to open and exhaust the air from the vessel 10.
Patent ES-343412-A1 (ES)
Title: Power steering pump
IPC: F04C15/06
Filed: 1967-07-26
Abstract: A rotary pump of the rocking-sliding slipper type comprises a plurality of axially aligned parts including a housing plate 20, Fig. 3, a pumping cartridge element 16, a pressure plate 17 and a cover plate 18 maintained in axial alignment with each other by bolts 21 and dowels 47, Fig. 5, and a thin sheet-form member 26 surrounding the pumping cartridge and the pressure plate to form an inlet zone I with the whole enclosed in a thin walled cap-shaped member 11 forming a reservoir R. The pumping cartridge 16 comprises a ring member 30 having an oval bore 32 abutted in two places by a rotor 32 to form a pair of diametral pumping chambers 33 and a plurality of spring- loaded slippers 40 radially and rockably movable in axially-extending peripheral notches 35 in the rotor. Hydraulic fluid from the zone I is admitted to the pumping chambers 33 through ports 34 and to the notches 35 through openings (not shown) and discharged at pressure therefrom axially through major and minor outlets 53, 54 respectively in the pressure plate 17 to a recess 57 in the cover plate 18 so that discharge pressure acts on the rear face of the pressure plate to urge the pressure plate 17 pumping cartridge 16 and housing plate 20 into sealing engagement. Pump discharge passes from the recess 57 through a port 55 in the pressure plate to an outlet chamber O and thence through an orifice 59, Fig. 2, and a passage 58, 62, 63, 64, 65 to a utilization point. Pump discharge pressure upstream and downstream of the orifice 59 acts on the opposite ends of a spring-loaded plunger 74 controlling ports 88 leading to the low pressure zone I. On rightward movement of the plunger, Fig. 3, hydraulic fluid is sucked into the zone I from the reservoir R through ports 90, 89. A spring-loaded loose ball valve 84 co-operating with a seat 85 which is a press fit in the plunger relieves excess pressure through radial ports (not shown), an annulus 87 and the ports 88.
Patent ES-346700-A1 (ES)
Title: Detector for bipolar binary signals with distortion correction capability
IPC: H04L25/22
Filed: 1967-11-02
Abstract: In a circuit for detecting bipolar signals (i.e. signals in which "zero" is a zero voltage and "one" is alternately positive and negative), the input signals are applied to a threshold detector producing monopolar signals and having its threshold obtained by comparing a variable voltage with the peak or average of the output voltage and applied through a differential amplifier preceding the detector. In the circuit shown, bipolar signals are passed through an equalizer EQ and a linear amplifier Q 1 , Q 2 to a threshold detector Q 3 , Q 4 . This produces a monopolar output which follows the input when it exceeds a threshold dependent upon its emitter voltage U 2 and the mean value of the voltage of the collectors of Q 1 and Q 2 . The peak output is detected by ACl and if the switch is in position 1 this output is compared with an adjustable reference U 3 and controls the mean current in Q 1 and Q 2 and thus the threshold. The output of the threshold detector is squared by Q, and if the signal is such that "zeros" and "ones" occur with equal frequency, as in pulse code modulated speech, the average value may be determined by AC2 and used to control the threshold.
Patent ES-348556-A1 (ES)
Title: Novel compositions for polyurethane coatings
IPC: C08G18/64
Filed: 1967-12-22
Abstract: Polyurethane coatings are prepared by reacting in a solvent an organic polyisocyanate with products of addition of phenols or phenol derivatives which contain at least one exchangeable hydrogen atom to unsaturated, straight- or branched-chain alcohols with 10 to 48 carbon atoms, which may be alkoxylated, and/or their reaction products with ethylene oxide or propylene oxide. Suitable phenols or phenol derivatives are phenol, polyhydric phenols, alkyl phenols, halogenated phenols and polynuclear phenols. Alcohols suitable for forming the addition product are decenol, dodecenol, hexadecenol, oleyl alcohol, linoleyl alcohol, linolenyl alcohol and particularly alcohols obtained from natural oils, fats and waxed and unsaturated Guerbet alcohols. The reaction products of the addition products with 1 to 6 mol. of ethylene oxide or propylene oxide per mol. of addition product are particularly useful. Conventional aliphatic or aromatic polyisocyanates may be used. Suitable solvents are ethyl acetate, ethylene glycol diacetate, benzene, toluene, xylene, methylene chloride and dioxan. Substantially stoichiometric quantities of polyisocyanate may be used, but when ethylene oxide or propylene oxide addition products are used an excess of polyisocyanate up to an NCO : OH ratio of 2À5 : 1 is recommended. Cross-linking of the products may be achieved by including trimethylolpropane in the reaction mixture and catalysts, especially triethylamine, may be used. The addition products may be prepared by reacting a phenol or phenol derivative with an unsaturated straight- or branched-chain alcohol with 10 to 48 carbon atoms, which may be alkoxylated at 100 to 250 C. in the presence of acid aluminium silicates as catalysts, especially aluminium silicates activated with mineral acids with a pH value of 3 to 5, which are used in an amount of 1 to 15% based on the reaction mixture. They may be ethoxylated or propoxylated in the conventional manner. Numerous examples of the addition products are described.
Patent ES-349259-A1 (ES)
Title: Gas-liquid finned heat exchanger
IPC: F28D7/10
Filed: 1967-12-29
Abstract: In a heat exchanger in which a hot gas flows in a duct 5 and heats a liquid flowing in a surrounding duct 4 by conduction through a wall 3, and in which the surface of the wall on the gas side is formed with fins 10a extending in the direction of gas flow, the gas passageway is gradually constricted in the direction of gas flow. As shown, a core 2a may be disposed in the gas passage and the constriction may be applied by tapering the core, the fins 10a being of uniform height. Alternatively the core may be cylindrical and the fins tapered (Fig. 1). In a further form which does not utilize a core (Fig. 4) the fins are tapered so as to increase in height in the direction of gas flow and opposing fins meet or nearly meet at a point (11) on the longitudinal axis of the heat exchanger. In this embodiment the gas duct may have a non- cylindrical shape in cross-section such as elliptical or polygonal.
Patent ES-352097-A1 (ES)
Title: Liquid heater
IPC: A47J31/54
Filed: 1968-03-28
Abstract: In a water heating apparatus having a heating tank 12 supplied from a basin 13 into which cold water is poured, the displaced hot water being delivered through pipes 19, 15, e.g. to a brewing apparatus, the edge of the basin projects upwardly through an opening in the top wall 22 of a surrounding cabinet and is sealed thereto by a resilient sealing strip 38. The basin is closed by a hinged lid 29 which seats on the strip 38, a hinged portion 30 of the lid being liftable separately to open a pouring aperture closed by a strainer 33. The siphon pipe 19 may be swung into a position connecting the inlet and outlet 16, 17, of the tank 12, whereby the tank is disconnected from the basin 13 and cold water flows straight from basin 13 through its outlet 15.