baber/WOPTO huggingface dataset:
Patent NZ-738846-A (NZ)
Title: Nucleophilic catalysts for oxime linkage
Inventor: SIEKMANN JUERGEN
IPC: A61K47/61
Filed: 2013-05-16
Abstract: The present invention relates to, inter alia, a method of conjugating a water soluble polymer to an oxidized carbohydrate moiety of a therapeutic protein, said method comprising contacting the oxidized carbohydrate moiety with an activated water soluble polymer under conditions that allow conjugation; wherein said activated water soluble polymer contains an active aminooxy group and the water soluble polymer is selected from the group consisting of starch, hydroxyalkyl starch (HAS), hydroxylethyl starch (HES), polysaccharides, pullulan, chitosan, hyaluronic acid, chondroitin sulfate, dermatan sulfate, dextran, and carboxymethyl-dextran, wherein the water soluble polymer is not polysialic acid (PSA). The water soluble polymer containing the active aminooxy group is prepared by a method comprising: (a) incubating a solution comprising an oxidized said water-soluble polymer with an aminooxy linker comprising the active aminooxy group under conditions that allow the formation of a stable oxime linkage between the oxidized water-soluble polymer and the active aminooxy linker, said conditions comprising a time period of between 1 minute and 24 hours; a temperature between 2°C and 8°C; in the presence or absence of light; and with or without stirring to thereby form the water-soluble polymer containing the active aminooxy group; and (b) purifying the water soluble polymer containing the active aminooxy group by a method selected from the group consisting of chromatography, filtration, dialysis, and precipitation, at a temperature between 2°C and 8°C. The carbohydrate moiety is oxidized by incubation with a buffer comprising an oxidizing agent selected from the group consisting of sodium periodate (NaIO4), lead tetraacetate (Pb(OAc)4) and potassium perruthenate (KRuO4), the oxime linkage is formed between the oxidized carbohydrate moiety and the active aminooxy group on the water soluble polymer; and the oxime linkage formation is catalyzed by the nucleophilic catalyst m-toluidine.
Patent NZ-748528-A (NZ)
Title: Push-off device and push-off vehicle comprising a push-off device
Inventor: FLIEGL JOSEF
IPC: B60P1/32
Filed: 2017-02-17
Abstract: The invention relates to a push-off device (12), in particular for agricultural transport goods, comprising a loading space (36) having a loading floor (18), two side walls (38) laterally adjacent thereto, and a push-off wall (14) that is slidable in the longitudinal direction (x) of the loading space (36) relative to a sliding floor (16), which in turn is slidable in the longitudinal direction (x) of the loading space (36) relative to the loading floor (18) of the loading space (36). The push-off device (12) has a first hydraulic cylinder arrangement (20), comprising at least one first hydraulic cylinder piston (24) that is movable in a first hydraulic cylinder tube (22). The push-off device (12) further has a second hydraulic cylinder arrangement (26), comprising at least one second hydraulic cylinder piston (30) that is movable in a second hydraulic cylinder tube (28). The push-off wall (14) is slidably mounted on the second hydraulic cylinder tube (28) in a longitudinal direction (x) of the loading space (36), and is slidable relative to the sliding floor (16) by means of the first hydraulic cylinder arrangement (20). Said sliding floor is slidable relative to the loading floor (18) of the loading space (36) by means of the second hydraulic cylinder arrangement (26). The invention further relates to a push-off trailer (10) having a push-off device (12).
Patent NZ-759884-A (NZ)
Title: Deep learning-based framework for identifying sequence patterns that cause sequence-specific errors (sses)
Inventor: KIA AMIRALI
IPC: G16B40/20
Filed: 2019-07-09
Abstract: The technology disclosed presents a deep learning-based framework, which identifies sequence patterns that cause sequence-specific errors (SSEs). Systems and methods train a variant filter on large-scale variant data to learn causal dependencies between sequence patterns and false variant calls. The variant filter has a hierarchical structure built on deep neural networks such as convolutional neural networks and fully-connected neural networks. Systems and methods implement a simulation that uses the variant filter to test known sequence patterns for their effect on variant filtering. The premise of the simulation is as follows: when a pair of a repeat pattern under test and a called variant is fed to the variant filter as part of a simulated input sequence and the variant filter classifies the called variant as a false variant call, then the repeat pattern is considered to have caused the false variant call and identified as SSE-causing.
Patent PT-105669-A (PT)
Title: Instalação de distribuição automática de produtos
Inventor: FEBRA ANTONIO FRANCISCO
IPC: A47F3/02
Filed: 2011-05-03
Abstract: O PRESENTE INVENTO REFERE-SE A UMA INSTALAÇÃO DE DISTRIBUIÇÃO AUTOMÁTICA DE PRODUTOS, EM ESPECIAL PRODUTOS HORTÍCOLAS, QUE COMPREENDE UM INVÓLUCRO (A), QUE COMPREENDE UM ESPAÇO DE ARMAZENAGEM E UM CONJUNTO DE, PELO MENOS, DUAS DISPOSIÇÕES COM UMA PLURALIDADE DE RECIPIENTES, TIPO ALCATRUZ, DE SUPORTE E DISTRIBUIÇÃO DOS REFERIDOS PRODUTOS, DISPOSTAS LADO A LADO E UM DISPOSITIVO DE PAGAMENTO E SELECÇÃO DOS PRODUTOS (7). O INVÓLUCRO (A) COMPREENDE UMA PAREDE FRONTAL (1) COM UMA PARTE TRANSPARENTE (1¿) QUE PERMITE A VISUALIZAÇÃO DOS PRODUTOS CONTIDOS EM ALGUNS RECIPIENTES DE CADA DISPOSIÇÃO DE RECIPIENTES, NO INTERIOR DA REFERIDA INSTALAÇÃO, PAREDES LATERAIS (3) E AINDA UM TELHADO (5), QUE PODE SER CONSTITUÍDO POR UM CONJUNTO DE PAINÉIS FOTOVOLTAICOS (6). CADA UMA DAS REFERIDAS DISPOSIÇÕES DE RECIPIENTES DESTINA-SE A CONTER UMA PLURALIDADE DE PRODUTOS SEMELHANTES PARA DISTRIBUIÇÃO E COMPREENDE, PELO MENOS, UM PAINEL LATERAL (11). CADA UM DOS REFERIDOS RECIPIENTES (10) ESTÁ ASSOCIADO A UM DISPOSITIVO DE LIGAÇÃO (12R) DOS RECIPIENTES (10), DE MODO A CONSTITUIR UMA CADEIA FECHADA. A REFERIDA CADEIA FECHADA ESTÁ MONTADA NUM CONJUNTO DE SUPORTE E ACCIONAMENTO, DESTINADO A FAZER A MOVIMENTAÇÃO DOS REFERIDOS RECIPIENTES DE MODO A, QUANDO UM UTILIZADOR ESCOLHER E PAGAR UM PRODUTO, OS REFERIDOS RECIPIENTES SEREM MOVIMENTADOS DE MODO A SER COLOCADO O PRODUTO ESCOLHIDO PELO UTILIZADOR JUNTO DE UMA ABERTURA, DE ONDE O MESMO PODE SER RETIRADO, APÓS A ABERTURA DE UMA TAMPA (T1).
Patent PT-109363-A (PT)
Title: Dispositivo e processo de aproveitamento de qualidade de rolhas de cortiça
Inventor: HUGO FERREIRA GUIMARÃES
IPC: B65D39/00
Filed: 2016-05-04
Abstract: A PRESENTE INVENÇÃO DIZ RESPEITO A UM NOVO DISPOSITIVO E PROCESSO DE APROVEITAMENTO DE ROLHAS DE CORTIÇA QUE COMPREENDE UMA PLATAFORMA DE SUSTENTAÇÃO (1), UM DISPOSITIVO (2) APTO A FAZER RODAR UMA ROLHA DE CORTIÇA, PELO MENOS TRÊS CÂMARAS DIGITAIS (3), (4) E (5) APTAS A RECOLHER IMAGENS DA SUPERFÍCIE DAS ROLHAS (CORPO E TOPOS), DOIS MEIOS DE SUSTENTAÇÃO (6) E (7), UM DISPOSITIVO DE DESCARGA DE ROLHAS (8) E UM DISPOSITIVO DE CORTE (9) APTO A SEPARAR PELO MENOS UMA ROLHA DE CORTIÇA EM DUAS METADES. A PRESENTE INVENÇÃO REALIZA A ESCOLHA DA MELHOR QUALIDADE DA SUPERFÍCIE DAS ROLHAS, SENDO O RESULTADO FINAL DO PROCESSO, UMA ROLHA DE CORTIÇA COMPOSTA POR DUAS OU MAIS PARTES DE MELHOR QUALIDADE DE DUAS OU MAIS ROLHAS.
Patent PT-116824-A (PT)
Title: Equipamento de proteção individual para o manuseamento de objetos
Inventor: INÊS SOUSA RIBEIRO
IPC: A41D19/00
Filed: 2020-10-14
Abstract: EQUIPAMENTO DE PROTEÇÃO INDIVIDUAL PARA O MANUSEAMENTO DE OBJETOS COMPREENDENDO UMA ESTRUTURA DE BASE (1); UM PEITILHO (2); UMA TIRA DE FIXAÇÃO AO PESCOÇO (3) QUE PODE INCLUIR UM PRIMEIRO MEMBRO DE AJUSTE DE COMPRIMENTO (11) E É LIGADA AO PEITILHO (2); E UMA TIRA DE FIXAÇÃO À CINTURA (4), QUE PODE INCLUIR UM SEGUNDO MEMBRO DE AJUSTE DE COMPRIMENTO (13), SENDO QUE O PEITILHO (2) COMPREENDE UMA ZONA DE PROTEÇÃO TÉRMICA (5) E UMA ZONA DE LIGAÇÃO (18) A DUAS LUVAS (16), QUE PODEM INCLUIR RUGOSIDADES (15) E ABERTURAS (19). A INVENÇÃO RESOLVE OS PROBLEMAS DA INSEGURANÇA NO MANUSEAMENTO DE OBJETOS QUENTES EM COZINHAS POR MEIO DA ZONA DE PROTEÇÃO TÉRMICA (5), QUE PODE INCLUIR ADICIONALMENTE TIRAS DE PROTEÇÃO TÉRMICA NO PEITILHO (20) E TORNA SEGURO O MANUSEAMENTO DE OBJETOS EXPOSTOS A ELEVADAS TEMPERATURAS, DEVIDO ÀS CARACTERÍSTICAS DE PROTEÇÃO CONTRA O CALOR POR CONTATO, ANTIDERRAPANTES E/OU ADERENTES DESSA ZONA.
Patent RO-88974-A (RO)
Inventor: SANFORD REDMOND
IPC: B65D75/58
Filed: 1983-11-16
Abstract: A dispenser package (10, 100) for flowable substances of the type where the flowable product is contained within a flexible pouch (22) adhered to a relatively stiff material (12) and may be opened along a fault line (24) or cut pattern scored in the relatively stiff material with one hand by folding the stiff ends towards one another into a "V" shape containing one or more dimples, pyramidal shapes (26) or other protrusions on the fault line (24) or fault area. The protrusions (26, 40, 52, 54, 56) not only increase and concentrate the stress forces, so that even very tough, high barrier materials may be used in constructing the package and will rupture at the protrusions by the aforesaid folding motion, but also control both the aperture shape and flow direction of the flowable substance as it is dispensed. The ability to make the package of tough materials enables the package to contain substances under pressure which subsequently will be dispensed. A sponge-like material (65, 70) also may be compressed within the package shaped so that a ' portion (66) will project from the package on opening for use as a swab for application of the contents.
Patent RO-89343-A (RO)
Inventor: KLAUS ANNEN
IPC: C07J7/00
Filed: 1983-11-21
Abstract: 6 alpha -Methyl corticoids of formula I    <IMAGE>  (I)  wherein   is a single bond or a double bond, R is acyloxy of up to 8 carbon atoms, and X is chlorine, hydroxy, or acyloxy of up to 8 carbon atoms, are pharamacologically effective substances.
Patent RU-94017677-A (RU)
Inventor: GAL PERINA T JA
IPC: C04B7/17
Filed: 1994-05-11
Abstract: FIELD: new building materials. SUBSTANCE: slag that results from pyrometallurgical treatment of high- calcium fly ash and gypsum are added to the binder composition composed of slag and high-calcium fly ash, the ratio of components being as follows (wt %): 24-30 high-calcium fly ash; 65-70 slag that results from pyrometallurgical treatment of high-calcium fly ash; and 5-6 gypsum. EFFECT: greater strength and improved properties of building materials. 3 tbl
Patent RU-94018051-A (RU)
Inventor: DROBOTENKO V V
IPC: C23C16/18
Filed: 1994-05-17
Abstract: FIELD: production of metal-oxide coatings by precipitation from solution. SUBSTANCE: method is accomplished by application of film-forming coating from a solution containing alkoxide of metal and other compounds with subsequent drying and thermal treatment in three variants. According to first variant the solution contains alkoxide of metal of general formula R-OM, where M-Ti, Zr, Sn, V, R-alkyl C-C,, acetic or propionic acid at molar ratio alkoxide: acid equal to 1:1, and ammonium chloride - 0.1 to 0.5 mass percent of the total mass of alkoxide. According to the second variant the solution contains alkoxide of metal indicated in the first variant, ammonium chloride of the same amount, and acetate or propionate of metal of groups I-VIII at molar ratio alkoxide: carboxylate equal to 1:1. According to the third variant the solution contains the same components as in the first variant and additionally chloride or nitrite of metal of groups I-VIII at molar ratio alkoxide:salt:acid equal to 1:1:2. Isopropyl alcohol n-butyl acetate, methyl ethylene glycol, tetrahydrofuran, ethylcellosolv, etc. are used as solvent. The solution is kept for a long time in contact with air, and for an unlimited long time - in a sealed closed container. Due to the increase of the time of solution "life", it becomes possible to obtain a qualitative uniform coating on large areas, for example, on a sheet having an area of 2.5x1.6 m. The temperature of thermal treatment makes up 200 to 350 C. EFFECT: improved method.
Patent RU-94032310-A (RU)
Inventor: ZENIN V V
IPC: G01N3/00
Filed: 1994-09-05
Abstract: FIELD: measuring equipment used for detection of fatigue cracks in materials and welds; can be used in atomic, aviation and outer space equipments, oil and chemical industries,, shipbuilding and other branches of engineering. SUBSTANCE: the detector of fatigue cracks in materials and welds has a DC source and a sensor. The novelty in the device is the fact that it is furnished with a decoder, first and second multiplexers, whose output lines are connected to the sensor lines, clock pulse generator and pulse counter, whose input is connected to the output of the clock pulse generator, and the output line of the pulse counter is connected to the input lines of the multiplexers and decoders, a storage connected to the output line of the decoder; the output line of the storage via a buffer amplifier is connected to the indicator, first and second one-shot multivibrators, whose inputs are connected to the clock pulse generator and a comparator, whose output is connected to the first input of the storage, whose second input is connected to the output of the first one-shot multivibrator via a gate pulse shaper; the output of the second one-shot multivibrator is connected to the control input of the current source, whose output is connected to the first input of the comparator and inputs of the first and second multiplexers, threshold voltage is applied to the second input. EFFECT: enhanced quality. 1 cl, 2 dwg
Patent RU-94032671-A (RU)
Inventor: CHIGAREV V V
IPC: B23K9/173
Filed: 1994-09-08
Abstract: FIELD: welding production, namely industrial railway road transporting systems. SUBSTANCE: method of arc welding of rails with multilayer filling of welded seam comprises steps of reciprocation motion of electrode with formation of mutually crossing separate portions; performing welding of rail stand at optimal mode and welding of rail head at modes being by 1.6-1.7 times higher than optimal one. That allows to receive equal - strength welded joint of optimal-volume welding bath. EFFECT: enhanced quality of welded joint. 1 tbl
Patent RU-94043627-A (RU)
Inventor: CHIFILEV N P
IPC: B60B1/00
Filed: 1994-12-09
Abstract: FIELD: transport; cross-country vehicles with low-pressure wheels. SUBSTANCE: increased elasticity low-pressure wheels with flexible spokes has toroidal chamber 1 filled with gas, and case 2 enclosing the chamber whose pattern cutting radius 1 is smaller than that of chamber 1, hub 3 and pairs of flexible crossed spokes 4 and additional spokes 5 connecting chamber 1 with hub 3. Spokes are arranged in radial plane and are connected with hub 3 and case 2. Spokes 4,5 come together in one point 7 on hub 3. Places of attachment of spokes 4,5 to case 2 are arranged in one radial plane in place of maximum width forming closed circuit providing equalizing of loads on spokes. EFFECT: enlarged operating capabilities. 6 cl, 1 dwg
Patent RU-94044989-A (RU)
Inventor: BALON L V
IPC: B61H7/08
Filed: 1994-12-27
Abstract: FIELD: rail transport. SUBSTANCE: drive of brake shoe of electromagnetic rail brake has power cylinder 3 with return spring 4 coupled through levers and joints with brake shoe. levers are arranged in form of scalene triangles 5 with joints fitted in corners. Joints at vertex of maximum angle are coupled with brake shoe, and joints at vertex of minimum angle, with rod and housing of cylinder. Joints at third vertex are coupled with vehicle frame by means of telescopic rods 6. Maximum length of telescopic rods A=B-C where B - distance from axle of telescopic rod -to-vehicle suspension joint 7 to working surface of rail 8; C - distance from axle of brake shoe suspension joint 9 to its working surface. EFFECT: enlarged operating capabilities by using device as weight transfer device. 1 dwg
Patent RU-94046199-A (RU)
Inventor: PETER RAU
IPC: G21C3/32
Filed: 1993-06-21
Abstract: FIELD: nuclear power engineering. SUBSTANCE: fuel element with elongated fuel-element can 2 has locking body 12 that in one locking position attained due to turning of cladding 6 about longitudinal axis enters slot 16 in cross-section of can 2 on inner side of elongated can 2 and that is protected against spinning in this locked position due to locking element 18 which is, essentially, retaining body mounted on locking body 12 for radial displacement of can 2 and provided with retaining drilling on wall of can 2 or it may be made in the form of retaining body mounted on locking body 12 for longitudinal displacement of can 2 and provided with retaining notch 22 on final edge of can 2 or with retaining slot 21 on inner side of can 2. EFFECT: improved design. 1 dwg
Patent RU-95104576-A (RU)
Inventor: FEDOROV S N
IPC: A61K35/34
Filed: 1995-04-06
Abstract: FIELD: medicine, ophthalmology. SUBSTANCE: pericardium is used as connective tissue for collagen isolation followed by collagen solution treatment with glycoseaminoglycans at concentrations 50-400 mcg/g, drying at 4 C for 16-24 h up to film formation. Material is used in surgery ophthalmology for patient treatment with glaucoma. EFFECT: improved method of preparing.
Patent RU-95105363-A (RU)
Inventor: SAGDEEV A M
IPC: A63H33/06
Filed: 1995-04-10
Abstract: FIELD: entertainment. SUBSTANCE: volumetric game-puzzle is manufactured in the form of polyhedron which six faces belong to faces of cube. Puzzle includes six play elements interacting with the aid of coupling elements. Play elements have same shape and dimensions. At least one of play elements is made from elastic material. Assembly of volumetric game-puzzle is accomplished due to deformation of one of play elements. EFFECT: expanded functional capabilities.
Patent RU-95105509-A (RU)
Inventor: POTEKHIN B N
IPC: G05D23/00
Filed: 1995-04-11
Abstract: FIELD: automatic control. SUBSTANCE: device is separable and has heat-insulated tube housing and working chamber, which joints are sealed by means of elastic insertions 10 so that inner chamber which is filled with liquid 12 is provided. Ends of working chamber are led to outer air in order to provide their maintenance. Outer envelope of tube housing is covered with wire spiral heater 3. Sleeve 11 is located in chamber with liquid 12. Sleeve has spiral grooves and is mounted for free movement when device is rocked. This results in possibility to stir liquid to achieve stable heating temperature. When device is connected to power supply 7 through control unit 8, heat element 3 is supplied. Outer housing envelope 1 and liquid 12 are heated. When given temperature is achieved, contacts of temperature regulator 6 are closed. Corresponding signal is sent to control unit 8 and power supply circuit of heat element 3 is switched off. Precision of temperature regulation is controlled by means of reference thermometer 5 and tuning by electric-contact thermometer 6. When temperature is kept, device is rocked in rotating unit 14. When device is inclined, sleeve 11 slides and runs liquid through its spiral grooves. This results in stirring of liquid and stable temperature along length of chamber. EFFECT: increased field of application and increased reliability of keeping temperature of objects which are located long cylindrical chambers. 2 cl, 2 dwg
Patent RU-95106641-A (RU)
Inventor: TOMAS A LOKARD
IPC: B23B29/04
Filed: 1993-06-14
Abstract: FIELD: mechanical engineering. SUBSTANCE: cutter holder has unit for control of a nozzle for directing cooling air. The unit comprises threaded base from one side and nozzle head from the other side. The threaded base can be screwed in or screwed out of the threaded opening in the housing of the cutter holder which is in communication with the initial passageway for cooling liquid to control the position of the head of the nozzle. The nozzle head directs the cooling liquid to the sides between the cutter and blank independently of the depth of cutting. EFFECT: enhanced reliability.
Patent RU-95110939-A (RU)
Inventor: JORG FRAJ
IPC: A61P33/02
Filed: 1994-04-02
Abstract: FIELD: medicine. SUBSTANCE: claimed invention describes compounds of formula I:wherein from radicals R, R, R, R, Rand Rfour radicals are hydrogen, and other radicals independently from each other in each case are C-Calkyl, these groups being attached to the same carbon atom or to two different carbon atoms or (b) form radicals R, R, R, R, Rand Rfive radicals are hydrogen, and other radical are C-Calkyl or hydroxymethyl, or salts thereof. Compounds of formula I and salts thereof inhibit ornithine-decarboxylase. EFFECT: improved properties of the title compounds.
Patent TW-200303077-A (TW)
Title: Semiconductor device and its manufacturing method
Inventor: OHNO HIROMASA
IPC: H01L21/56
Filed: 2002-10-29
Abstract: The problem to be solved by the present invention is to prevent resin leakage and increase production efficiency. The present invention contains the followings: a substrate 7, which contains plural connection terminals 72 formed at the periphery of the recessed portion 7b; plural lump shore faces 7h, which are arranged and disposed at the periphery of the connection terminals; a semiconductor chip 1, which is disposed at the recessed portion 7b; plural conduction wires 4, which connects the electrode pad 1a of the semiconductor chip 1 with the connection terminal 7e of the substrate 7; the encapsulation portion, which is buried in the recessed portion 7b; and plural ball electrodes, which is disposed on the lump shore face 7h of the substrate 7. In addition, there are nominal wirings 7i disposed between plural connection terminals 7e of the substrate 7 and plural lump shore faces 7h, and are wrapped by the soldering resistant film 7f. Thus, because the gap between mold surface 12d of the upper mold 12 and surface of the substrate 7 is buried by nominal wirings 7i and the wrapped soldering resistant film 7f when locking the mold of formation mold, it is capable of preventing the leakage of resin 8 for encapsulation when resin is injected. Therefore, the result of increasing production yield of formation is obtained.
Patent TW-200408876-A (TW)
Title: A method of utilizing color photoresist to form black matrix and spacers on a control circuit substrate
Inventor: CHENG JIA-SHYONG
IPC: G02F1/1362
Filed: 2002-11-20
Abstract: A method of utilizing color photoresist to form black matrix and spacers on a control circuit substrate is provided. Utilizing the character of the red and the blue photoresist having non-overlapping transmittance region in the visible light region, a black matrixes consisting of overlapping red and blue photoresist on control devices are used to prevent the photo current occurring in the off state of the control devices. In addition, four layers of three different color photoresist plus another color photoresist are overlapped to form spacers on metal lines.
Patent TW-200410148-A (TW)
Title: Portable memory card
Inventor: Zhuang hai-feng
IPC: G06K13/00
Filed: 2002-12-05
Abstract: The present invention discloses a portable memory card, which is used in a host device supporting universal serial bus specification. The memory card includes at least a random access memory for reading and writing data, a data converter electrically connected with the random access memory, a microcontroller for controlling the data converter to conduct the data reading and writing on the random access memory, and an universal serial bus connector coupled between the host device and the data converter. Furthermore, the memory card according to the present invention also includes a battery for the power required by the self-data update on the random access memory, and a power controller for controlling the charging and discharging of the battery.