baber/WOPTO huggingface dataset:
Patent EC-SP099652-A (EC)
Title: Proceso abreviado de purificacion para la produccion de polisacaridos capsulares streptococcus pneumoniae
Inventor: MORAN JUSTIN KEITH
IPC: A61K39/09
Filed: 2009-09-23
Abstract: Se describe un proceso abreviado para producir una solución que contiene polisacáridos capsulares esencialmente purificados a partir de un caldo de lisado celular de Streptococcus pneumoniae. La ultrafiltración y diafiltración de un lisado clarificado de S. pneumoniae, seguido por ajuste del pH hasta menos de 4,5, preferiblemente más o menos 3,5, precipitó por lo menos 98% de la proteína contenida en la solución sin afectar seriamente al rendimiento de polisacárido. Además, después de la ultrafiltración y diafiltración y acidificación hasta un pH de menos de 4,5, la filtración utilizando carbono activado precipitó por lo menos 90% de la proteína restante sin afectar seriamente el rendimiento del polisacárido. Ejemplos de serotipos no limitativos de S. pneumoniae que pueden ser purificados utilizando el proceso abreviado de la invención son 1, 4, 5, 6, 6B, 7F, 9V, 14, 18C, 19A y 23F.
Patent EC-SP099805-A (EC)
Title: Nuevos derivados de ácido dicarboxílico como agonistas de los receptores de s1p1
Inventor: SCHWARTZ JEAN-CHARLES
IPC: A61K31/4245
Filed: 2009-12-15
Abstract: La presente invención se refiere a nuevos compuestos de fórmula (I) que poseen actividad agonista con respecto a los receptores de esfingosina-1 -fosfato (S1P), a su procedimiento de preparación y su uso como agentes inmunosupresores. La invención también se refiere a composiciones farmacéuticas que contienen estos compuestos y al uso de estos compuestos para el tratamiento/la prevención de enfermedades y condiciones mediadas inmunológicamente y condiciones o enfermedades inflamatorias.
Patent EC-SP951513-A (EC)
Title: Dispositivo modular en bandejas recipientes para la conservacion de alimentos
Inventor: DE JAEN TOLBANOS RAFAEL
Filed: 1995-08-18
Abstract: Dispositivo modular en bandejas recipientes para la conservacion de alimentos, constituido a partir de una pluralidad de bandejas recipientes (39 y un soporte para las mismas (2) flexible y articulado, adoptando las bandejas recipiente la configuracion planta rectangular y contando con un grosor proporcional hueco interiormente, disponiendo cada uno de los soportes al menos de dos recipientes (3) separados entre si, que sobresalen por ambas caras de la bandeja soporte (2), estando destinados a guardar y a conservar alimentos embutidos principalmente, estando rematados los recipientes (3) en su parte superir por una tapa de cierre hermetico (3') y de caracter transparente, emeergiendo de una de las ramas mayores del soporte (2), una configuracion semiesferica o similar, las cuales se insertan por encastracion de una abertura similar (7), a traves de una canalizacion (8) situada en una emergencia trapezoidal dimanada de los cuerpos (4), unidos entre si por un elemento flexible(5), que permite voltear. En sustitucion del soporte (23), puede utilizarse soporte (2'), portador de recipientes (3) con tapas transparentes y hermeticas (3'').
Patent EC-SP961706-A (EC)
Title: Compuestos acido pirrolidinil hidroxamico y su procedimiento de produccion
Inventor: FUMITAKA ITO
IPC: C08L1/00
Filed: 1996-03-29
Abstract: Esta invención se refiere a nuevos derivados del ácido hidroxámico y sus sales farmacéutyicamente aceptables y a composiciones farmacéuticas que los contienen. Estos compuestos y composiciones son útiles como agentes analgésicos, antiinflamatorios, diuréticos, anestésicos o neuroprotectores, o como un agente para el tratamiento de la apoplejía o enfermedades funcionales intestinales como el dolor abdominal, para el tratamiento de un mamífero, especialmente un sujeto humano.
Patent FI-19992350-A (FI)
Inventor: HARIHARAN RAMALINGAM
IPC: G10L15/02
Filed: 1999-10-29
Abstract: A speech recognition feature extractor includesa time-to-frequency domain transformer for generating spectral values in the frequency domain from a speech signal;a partitioning means for generating a first set and an additional set of spectral values in the frequency domain;a first feature generator for generating a first group of speech features using the first set of spectral values;a additional feature generator for generating an additional group of speech features using the additional set of spectral values; the feature generators arranged to operate in parallel,an assembler for assembling an output set of speech features from at least one speech feature from the first group of speech features and at least one speech feature from the additional group of speech features, and an anti-aliasing and sampling rate reduction block, where the first and the additional set of spectral values comprise at least one common spectral value.
Patent FR-1604356-A (FR)
Title: Ceramic piezoelectric transducers - of perovskites with manganese and nickel additions
IPC: C04B35/46
Filed: 1968-06-07
Granted: 1971-11-08
Abstract: Ceramic piezoelectric materials and transducers made form solid solutions in the ternary system PbTiO3 -PbZrO3 - Pb(Mg1/3Nb2/3)O3 with addition of 0.1 to 5% NiO and 0.1 to 5% MnO2. More specif. compsns. within the area 50, 0 to 6, 25% Pb(Mg 1/3 Nb 2/3) O3; 50, 0 to 25, 0% PbTiO3; 62, 5 to 12, 5% PbZrO3 plus 1.5 to 6% (MnO2 + NiO) with coupling factors Kp>30%; and Pb(Mg1/3Nb2/3) 0.375 Ti0.375Zr0.25O3, 0.5% MnO2, 0.5% NiO and Pb(Mg1/3Nb2/3)3.4375Ti0.4375Zr0.125O3, 0.5% MnO2, 0.5% NiO with coupling factors Kp >=45%. The materials combine high mechanical quality factor with high Kp plus relatively high dielectric constant and low losw factor.
Patent GB-1051210-A (GB)
IPC: F16D65/46
Abstract: 1,051,210. Internal shoe drum brakes. AUTOMOTIVE PRODUCTS CO. Ltd. Feb. 24, 1964 [Feb. 22. 1963], No. 15121/66. Divided out of 1,042,061. Heading F2E. A brake shoe adjusting means for an internal shoe drum brake comprises a housing 15 connected to the brake back plate and having a bore in which are slidably arranged two sleeves 31, 32 each in threaded engagement with a tappet 28, 29 respectively. The sleeves 31, 32 are provided adjacent their inner ends with teeth with which a pinion 37, spring loaded towards the sleeves, meshes. On rotating the pinion by means of the flats on shaft 37a, the sleeves rotate in opposite directions to move the tappets towards or away from each other, the ends of the tappets engaging one pair of adjacent ends of the brake shoe assemblies. A flange 34 on the sleeve 31 limits its relative movement in one direction with respect to the housing.
Patent GB-1051580-A (GB)
IPC: C07J1/00
Abstract: 1,051,580. 7-Methylene-steroids. BRITISH DRUG HOUSES Ltd. Nov. 17, 1965 [Dec. 3, 1964], No. 49166/64. Heading C2U. Novel 7-methylene steroids of the partial structure are prepared by reaction of the corresponding 7 - unsubstituted - 6 - keto - 3x,5 - cyclo - steroids with formaldehyde and the salt of a secondary amine. The reaction is preferably effected with paraformaldehyde and an amine salt such as dimethylamine, diethylamine or piperidine hydrochloride in an inert solvent such as a lower aliphatic alcohol or dioxan at 70‹ to 100‹ C. The steroids may be of the androstane, 19-norandrostane, pregnane, 19-nor-pregnane, cholestane or spirostane series and may contain hydroxy or acyloxy groups at positions 11, 12, 14, 15, 16, 17, 20 or 21; 16α, 17α-hydrocarbondioxy groups; carbonyl groups at positions 11, 12, 15, 16, 17 or 20 which may be protected as ketals, enol ethers or enamines; alkyl groups, particularly methyl groups at positions 11, 12, 16, 17 or 18 or ethyl at 17; lactone and ether residues such as -O.CO.CH 2 .CH 2  at 17, ether groups at 16 and ether bridges at 18 and 20; halogen atoms at positions 9. 16 and 21; and A<SP>9(11)</SP>-double bonds. Examples are given. 17α - Methyl - 3α, 5 - cycloandrostan - 17# - ol - 6-one is prepared by reacting 6#-hydroxy-3,5- cycloandrostan-17-one with methyl magnesium bromide to give 17α-methyl.3α,5-cyclo-androstan-6#, 17#-diol and oxidizing this. 17α Acetoxy - 3α,5 - cyclopregnane - 6,20 - dione is prepared by treating 17α-acetoxy-3#- hydroxy-pregn-5-en-20-one with p-toluene-sulphonyl chloride to give 17α-acetoxy-3#-p-toluenesulphonyloxy - pregn - 5 - en - 20 - one, heating this with sodium citrate in acetone and water to give 17α - acetoxy - 3α,5 - cyclopregnan - 6# - ol - 20-one and oxidizing this.
Patent GB-1054353-A (GB)
IPC: C30B31/16
Abstract: 1,054,353. Boron. ASSOCIATED SEMICONDUCTORS MANUFACTURERS Ltd. March 26, 1965, No. 12932/65. Headings C1A and C1M. [Also in Division H1] A boron diffusion source comprises a vessel having a porous silica portion which has a layer of borosilicate glass on its surface. The layer of borosilicate glass is preferably formed by placing the vessel in a furnace and heating it together with B 2 O 3 . The ratio of B 2 O 3 /SiO 2  in the layer is controlled by the temperature of treatment. In Fig. 2, silicon discs are placed within a porous silica vessel 6 coated with borosilicate glass. The vessel is heated to 700‹ to 1135‹ C. in a furnace 5 which also contains boron trioxide 7 and a nitrogen gas stream 8. Boron diffuses into the silicon discs which also get a covering of borosilicate which may be removed by washing in 40% HF. In an alternative embodiment, the B 2 O 3  source 7 is absent and a stream of N 2  and O 2  is used to aid diffusion.
Patent GB-1228201-A (GB)
IPC: C07C45/50
Filed: 1968-04-26
Abstract: 1,228,201. Oxidation catalysts. MONSANTO CO. 26 April, 1968 [27 April, 1967 (2); 5 June, 1967], No. 19918/68. Heading B1E. [Also in Division C2] A rhodium coordination complex catalyst contains as liquid an MR 3  group where M is is N, P, As or Sb and the R groups are organic at least one being an aryl or aryloxy group provided that when used in solution MR 3  is present in a stoichiometric excess and that when used in the vapour phase the catalyst complex is supported on a solid carrier and contains as liquids at least two MR 3  compounds, CO and at least one halogen selected from Cl, Br and I. Carriers specified include pumice, Al 2 O 3 , SiO 2 , SiO 2 -Al 2 O 3 , MgO, TiO 2 , ZrO 2 , CaO, MgSiO 3 , SiC, C, zeolites, organic polymers and various clays. Specified pore size s from 0.05 to 2.0cm<SP>3</SP>/g and particle size is from 400 mesh/inch to 3/8 inch. Many Rh complexes exemplified and starting compounds may contain halogen, SnX 3 , K and H.
Patent GB-1228203-A (GB)
IPC: B65D51/24
Filed: 1968-08-30
Abstract: 1,228,203. Opening containers; container closures. BOXAL BEAUREPAIRE S.A. 30 Aug., 1968 [5 Sept., 1967], No. 41518/68. Headings B8D and B8T. A metallic container 1, e.g. of tin or aluminium, having an annular rib 3, is sealed by a membrane 4, e.g. of metal, scored underneath at 5, and a tight fitting plastics cover 2 having projections 7. Upon removing, inverting and replacing the cover 2, its centrally bulged part 6 distends the membrane 4 downwards and the projections 7 pierce the membrane above the scoreline 5. Rotation of the cover 2 severs the membrane 4 which falls and rests upon a collar 3a, or is prevented from falling by adhesive on the cover 2 or on itself, or by a suction cup on, or recessed in, the cover. The cover 2 may house a spoon, Fig. 2 (not shown), or a predetermined quantity of a substance to be mixed with the container's contents. In a modification, Fig. 5 (not shown), the cover 2 is fitted outside the container 1 by means of a downward extension to an annular projection 2b, the inner flange 2a being omitted.
Patent GB-1232014-A (GB)
IPC: B60V3/02
Filed: 1967-06-02
Abstract: 1,232,014. Air cushion vehicles. HOVERCRAFT DEVELOPMENT Ltd. 30 May, 1968 [2 June, 1967; 3 April, 1968], Nos. 25688/67 and 16025/68. Heading B7K. [Also in Division B8] A gas cushion device has an inflatable base 2 from which a flexible wall structure 4 extends, said wall comprising a succession of independently contiguous wall members of the form disclosed in Specification 1,043,351. The wall and base define a gas cushion chamber 5 to which gas may be supplied through inlet pipe 6 via orifices 8 in the lower face of the base 2. In its inflated state the device may be used to carry a load 15, the device being placed beneath the load, which is preferably rasied on legs or like means, while deflated. An air compressor driven by an internal combustion engine may be attached to the load or device to produce a selfcontained transport system which is particularly suited to being towed between a factory and a ship since it can support a load over water. The upper and lower surfaces of base 2 may be joined, either at a central point or along the circumference of a circle whose centre is at said central point, Fig. 3 (not shown), to reduce sag in the base 2 caused by tensile forces from the wall members. A rigid ring or plate may be attached to the lower face of the base 2 to retain the shape of the device when it is deflated, and the base may have a concertina structure. The devices may be used to lift and move a crashed aircraft, Fig. 8 (not shown), by placing devices beneath the aircraft and inflating them from compressed air cylinders or an air compressor mounted in a vehicle. The devices may also be used with a conveyer belt, see Division B8.
Patent GB-1232147-A (GB)
IPC: G05F1/00
Filed: 1969-04-01
Abstract: 1,232,147. Automatic optimization. DORNIER SYSTEM G.m.b.H. April 1, 1969 [Oct.19, 1968] No.16953/69. Heading G3R. In a system for automatically maintaining the product of two inversely related variables at a maximum, each variable is decreased in turn, the changeover being effected by a switch which operates when the variable being decreased falls to a predetermined fraction of its previous initial value. In Fig. 4, an electrical source K, such as solar cells on a satellite, supplies a load V through a choke L and a diode D. A switch T, which may be a contact, a transistor, or a thyristor, is operated intermittently by a logic circuit SL so that, when the switch is closed, the source output voltage U falls and the current I rises whereas, when the switch is open the current falls and the voltage rises. The value of voltage or current Uα, I# from which the fall takes place is measured and stored by capacity or other time delay means SpM 1  or SpM 2  and a predetermined fraction K of the measurement is compared with the instantaneous value of U or I so that logic circuit SL changes switch T when the voltage or current has fallen to the predetermined fraction of its initial value. The switching gradually shifts the mean value of the small voltage and current excursions until maximum power is obtained and, thereafter, this condition is maintained despite variations of the voltage-current characteristic e.g. due to different locations of the satellite relative to the sun. In a modification, the logic circuit controls an integrating circuit which varies the source instead of the load on it.
Patent GB-1233616-A (GB)
IPC: B65B51/06
Filed: 1968-06-28
Abstract: 1,233,616. Applying adhesive tape. BEIERSDORF N.V. 28 June, 1968 [29 June, 1967], No. 31043/68. Heading B8F. An apparatus for closing boxes and similar packages by the application of adhesive tape on at least an upper face of the boxes comprises conveyer means 3 for moving boxes such as 34 along a conveyer track 2, lateral parallel guidemeans 6, 7 for aligning each box 34 with respect to the track, an elongate pressure member 11 mounted for reciprocating vertical movement above the track and counterbalanced by a weight 33, and an adhesive tape applicator device 26 carried by the member 11 and adapted to apply a length of adhesive tape 47 to the box 34<SP>1</SP> advancing beneath the pressure member. The member 11 has further guide means 12<SP>1</SP> engageable by an advancing box to raise the member 11 to a height allowing the box to pass underneath, and a locking device 20-23 adapted to lock the member 11 in one of a plurality of vertical positions. In operation, a box 34, positioned on the roller tracks 2 so that the flaps 35 extend at least approximately longitudinally of these tracks, is engaged by a pair of drive members 5 which advance the box between the lateral guide rails 6 and 7 and below the entry ends 12<SP>1</SP> of the pressure member 11. The upper flaps 35 of the box 34 are gradually closed until the front edge of the box engages the entry ends 12<SP>1</SP> and raises the member 11. When the box has reached the position 34<SP>1</SP> its front edge actuates a switch 24 controlling the device 20- 23 to lock the member 11 against further upward movement. When the front surface of the box engages the roller 27 of the upper applicator 26, the cut-off end of the tape 47 lying against this roller is placed against the box front surface and sticks thereto. The advancing box then swings the roller 27 upwards to pass underneath, the adhesive tape being pressed against the upper surface of the box. A knife (not shown) cuts the tape 47 as soon as the rear surface of the box has passed the roller 27. The loose rear end of the cut-off length of tape is pressed against the box rear surface by the roller 28. After the length of adhesive tape has been fully applied and the rear side of the box has passed the applicator 26 a trip dog 44 on the conveyer chain 3 actuates a switch 25 which disengages the locking device from the member 11, which returns to its lowermost position. The output of the apparatus may be increased by providing extra sets of members 5. Two further fixed slides similar to the slides 12 may be arranged in the plane of the roller tracks 2 on both sides of a lower tape applicator 26<SP>1</SP>, adapted for sealing boxes having flaps on the lower surfaces, and the adhesive tape applicators 26 and 26<SP>1</SP> may be replaced by similar devices for applying gummed tape which is not self-sticking but has to be moistened before being applied. The rails 6, 7 have a self centring mechanism 40, 41 (Fig. 1, not shown).
Patent GB-1238338-A (GB)
IPC: D06F39/08
Filed: 1968-09-10
Abstract: 1,238,338. Switches in washing machines. PATINVEST PATENT-UND INVESTMENT A.G. 10 Sept., 1968 [15 Sept., 1967], No. 42966/68. Heading D1A. [Also in Division H1] A washing machine is provided with a switch unit comprising a casing enclosing two switches for controlling the operation of different elements of the machine. One of the switches is controlled electromagnetically in response to the temperature of liquid in the machine and the other is controlled by the hydrostatic pressure of the liquid. In the construction shown there is one electrically operated switch with a fluid-pressure operated switch on each side, within a common housing, see Fig. 1 (not shown). The electrically operated switch, Fig. 2 comprises a fixed contact 6 and a moving contact 9 on a downwardly biassed spring blade. An electromagnet 10 has a pivoted armature 15 having its free end linked with the spring blade by a pin 19. Fixed contact 6 may alternatively be above scoring contact 9, as shown in dotted lines. Each fluid-pressure operated switch, Fig. 4, comprises an inlet tube 24 and a diaphragm 23 controlling a lever 27 by means of a tappet 26, against the action of an adjusting spring 28, so as to snap over contact spring 31 by means of compression spring 35, connected between arm 37 and switch blade 31. Contact spring 31 carries contact 32 between fixed contact 33 and adjustable contact 34. The electromagnetically actuated switch may be operated by a thermistor through an amplifier. (For Figures see next column)
Patent GB-1250870-A (GB)
IPC: F28F1/42
Filed: 1970-10-05
Abstract: 1,250,870. Multiple-effect and flash evaporators; desalination of water. PHELPS DODGE COPPER PRODUCTS CORP. 5 Oct., 1970 [8 Oct., 1969], No. 47302/70. Heading B1B. [Also in Division F4] A heat exchange tube 10 (see Division F4) has in its wall at least one helical corrugation 11 of the asymmetrical cross-section shown in Fig. 2a. Fig. 2 shows the tube in one effect of a multiple-effect, falling-film evaporator for the desalination of sea water. The tube has at its upper end a distribution wier 16 whereby brine from a pool 15 descends as a thin film 17 on the tube wall. The tube is heated externally by steam from the previous effect; and water is thereby evaporated from the brine to mix with water vapour from the previous effect passing downwardly through the centre of the tube (as denoted by the arrows). The corrugations 11 are said to cause increasing turbulence in the downwardly flowing film to enhance heating of the film and the evaporating effect. The currugated tubes can also be used as preheater/condenser tubes for multi-stage flash evaporators.
Patent GB-1256824-A (GB)
IPC: B65B9/06
Filed: 1970-01-27
Abstract: 1,256,824. Pill packaging machine. R. J. DWYER. 27 Jan., 1970 [22 July, 1969], No. 3935/70. Heading B8C. A machine for packaging predetermined numbers of pills in packages printed in situ comprises a hopper 13 having a continuously rotating disc 26 which centrifugally feeds a row of pills through an arcuate guide 15 to a reciprocating feeder 17 having an open-bottomed cavity 16 from which pills periodically fall through a shoot 25 into an intermittently fed web 30 folded into a U-shape by a plate 32 and intermittently rotating rollers 33. The machine components are synchronized via an electric eye 67 scanning spaced web markings so that during each dwell period a horizontally reciprocating head 37 bears against a P.T.F.E. coated rubber plate cushion to print on web 30, laterally reciprocating sealing and perforating blocks 47, 48 press the cohesive pressure sensitive web folds vertically together at package length intervals and, if required, cutters 55, 56 sever packages from the web. The rollers 33 form the top seal and the plate 32 is formed with a cam surface 32a for directing the pills forwardly within the web. The pill feeder 17 reciprocates in ways 22 and the cutters 55, 56 which are mounted on a common upper pivot 57 are actuated via pins 59 connected to the blocks 47, 48. A printing tape 35 e.g. metal foil is fed from a reel 35a under and up one side of the plate 32, to pass over a guide 35b to a take-up reel 36 connected via a pulley 44-46 to a roller 41 which is actuated during retraction of the head 37 by a one-way clutch and rack and pinion 43, 42. The hopper 13 and the feeder 17 which may be of plastics may be replaced by similar structures accommodating pills of different size and number.
Patent GB-1259397-A (GB)
IPC: H04B7/185
Filed: 1969-09-18
Abstract: 1,259,397. Satellite communication system. INTERNATIONAL STANDARD ELECTRIC CORP. 18 Sept., 1969 [25 Sept., 1968], No. 46059/69. Heading H4L. A ground station e.g. B, Fig. 1, for a time division multiple access satellite communication system includes pseudo noise generator pnG, Fig. 3, for transmitting a pseudo-random pulse sequence b, Fig. 2, having a repetition period equal to the time division frame (e.g. 125 Ás.) and an amplitude very much less than the normal system amplitude power, correlation receiving means KEP for receiving back the pulse sequence from the satellite and producing pulses c, Fig. 2, indicating the beginning of each sequence relative to the satellite time slot sequence, already occupied by reference station A and station C, and control unit Zst for shifting the transmission time position of the sequence until the pulses C (inset pulses) coincident with the beginning of the sought time slot and then commencing the transmission of the shown preamble and information P.C.M. pulse sequence. The pseudo-random pulse sequence may be orthogonal or quasi-orthogonal to the corresponding sequences from the other stations to reduce cross interference and may be produced by pseudo-noise, from Barker-codes or Walsh-functions. After the above initial time slot synchronization, the received back preamble may be used to check the synchronization. The pseudo-random pulse sequence may be transmitted by the station when it is not transmitting its preamble and information. The information from 24 channels (eight bits per channel) is stored in store Sp to await transmission, and the preamble is added by means PS. Switches S1 and S2 operated by unit Zst switch over from the pseudo-random pulse generation to the normal transmissions. The station's own preamble and that of the reference station A are respectively received by correlators KEE and KEB.