baber/WOPTO huggingface dataset:
Patent CA-2517325-A1 (CA)
Inventor: TYGER KAREN
IPC: B81B7/02
Filed: 2005-08-26
Abstract: Due to the bi-stable nature of interferometric modulator elements, the state of each modulator element may be held at either an actuated or a released state with a common voltage difference. Because modulator elements often require less time to change states than is allotted in a line time, power drawn by an array of modulator elements may be reduced by disabling one or both of a row and column voltage boost module, which are configured to amplify an input power source to a level that is suitable for driving modulator elements. If the column voltage is removed during the latter portion of a line time, for example, the row voltage is set to a level that is sufficient to maintain a voltage difference between the row voltage and the floating column voltage within a stability voltage range during the remainder of the line time.
Patent CA-2518944-A1 (CA)
Title: Inhibitors of extracellular hsp90
Inventor: EUSTACE BRENDA K
IPC: G01N33/50
Filed: 2004-03-09
Abstract: The present invention describes the inhibitors of extracellular Hsp90. The inhibition of extracellular Hsp90 leads to a reduction of the invasiveness of the tumor cells. Furthermore, the invention relates to the use of molecules inhibiting extracellular Hsp90 function for the manufacture of a medicament for the treatment or prevention of invasion and/or metastatic potential of cancer cells.
Patent CA-2521113-A1 (CA)
Title: Fluorescently tagged ligands
Inventor: MIDDLETON RICHARD JOHN
IPC: C07H19/16
Filed: 2004-03-31
Abstract: Library comprising a plurality of tagged non-peptide ligands of formula (I):  (Lig JL)m L(JT Tag) m (JTL(JLLig)m)p including and salts thereof comprising one or a plurality of same or different ligand moieties Lig each linked to a one or a plurality of same or different tag moieties Tag via same or different linker moieties L and same or different linking site or linking functionality JT and JL wherein Lig comprises a GPCR ligand, an inhibitor of an intracellular enzyme or a substrate or inhibitor of a drug transporter; L is a single bond or is any linking moiety selected from a heteroatom such as N, O, S, P, branched or straight chain saturated or unsaturated, optionally heteroatom containing, CI-600 hydrocarbyl and combinations thereof, which may be monomeric, oligomeric having oligomeric repeat of 2 to 30 or polymeric having polymeric repeat in excess of 30 up to 300; Tag is any known or novel tagging substrate; m are each independently selected from a whole number integer from 1 to 3; p is 0 to 3 characterised in that linking is at same or different linking sites in compounds comprising different Lig, JL, L JT and/or - Tag and is at different linking sites in compounds comprising same Lig, JL, L JT and/or - Tag; process for the preparation thereof; process for the preparation of a library compound of formula (I) or a precursor of formula (IV); method for selecting a compound of formula (I) from a library thereof;  compound of formula (I) associated with information relating to its pharmacological properties; a novel compound of formula (I) or precursor of formula (IV); uses thereof; methods for binding or inhibition therewith; use of a fluorescent target therewith; a modified cell surface GPCR and cells expressing the same; and a kit comprising a compound of formula (I) and a target therefor.
Patent CA-2523079-A1 (CA)
Title: Solid pharmaceutical preparation containing levothyroxine and/or liothyronine salts
Inventor: RANEBURGER JOHANNES
IPC: A61K9/16
Filed: 2004-05-03
Abstract: The invention relates to a solid pharmaceutical preparation containing water-soluble salts of Levothyroxine and/or Liothyronine as active agent, wherein water activity of the pharmaceutical preparation measured at room temperature is set to values below 0.4, preferably 0.1 to 0.3.
Patent CA-2523296-A1 (CA)
Inventor: OEBERG FREDRIK
IPC: E21D21/00
Filed: 2004-05-12
Abstract: Method and device for rock bolting, wherein a tubular bolt (2) with closed cross-section is inserted and expanded for anchoring inside a bore hole (12) , wherein the tubular bolt is expanded to contact in the inner portion of the bore hole, a tension element (3, 7, 8, 9) which is arranged in the outer portion of the bore hole with an inner part (7) attached to the tubular bolt (2) is pre-stressed and a settable medium is injected into the outer portion of the bore hole (14) between (27) the tension element and the wall of the bore hole and is allowed to set.
Patent CA-2524423-A1 (CA)
Title: Lighted elastomeric gasket
Inventor: PUGLIESE ANGELO VITO JR
IPC: A47K3/02
Filed: 2005-10-26
Abstract: A gasket for a spa shell includes a body formed of an at least partially translucent material. The gasket includes a top ring configured to abut a top surface of the spa shell and a bottom ring configured to abut a bottom surface of the spa shell. In one embodiment, the gasket includes an indentation configured to receive light from a light source for transmission through the body. The gasket may be formed with an elastomer.
Patent CA-2525270-A1 (CA)
Title: Arc hood and power distribution system including the same
Inventor: WEISTER NATHAN J
IPC: H01H9/34
Filed: 2005-10-31
Abstract: An arc hood includes a housing having a first chamber with two ends, a top and a bottom having an opening, and a smaller second chamber disposed on the top of the first chamber. The smaller second chamber includes two ends, a top and a bottom. Each of the ends of the second chamber have an opening, are disposed above the top of the first chamber, and are recessed from a corresponding one of the ends of the first chamber. The chambers define a passageway between the opening of the bottom of the first chamber and the openings of the ends of the second chamber. One or more baffles are within the housing and are disposed between the opening of the bottom of the first chamber and the openings of the ends of the second chamber. A seal is disposed about the opening of the bottom of the first chamber.
Patent CA-2525782-A1 (CA)
Title: Degradation of glycosaminoglycans in extracellular matrix to treat cns injury
Inventor: ROY GARGI
IPC: A61K38/51
Filed: 2004-05-17
Abstract: This disclosure relates to compositions capable of use in the treatment of spinal cord injuries and related disorders of the central nervous system (CNS), and in particular, compositions including proteoglycan degrading molecules and compositions capable of blocking and/or over coming the activi ty of neuronal growth inhibitory molecules, as well as fusion proteins which includes a proteoglycan degrading domain and a domain capable of blocking an d or over coming the activity of neuronal growth inhibitory molecules.
Patent CA-2526938-A1 (CA)
Inventor: ROUILLARD CAROL ANNE
IPC: A01N59/00
Filed: 2004-05-11
Abstract: The invention relates to a multi-component chlorine dioxide producing system.  The invention produces effective amounts of chlorine dioxide in five minutes or less without instantaneous production or loss of chlorine of dioxide. The invention further includes a dispensing apparatus to allow for the dispensing of the multi-component system to allow for insitu production of chlorine dioxide.
Patent CA-2530646-A1 (CA)
Inventor: SCHALKEN JACK A
IPC: C12Q1/68
Filed: 2004-06-30
Abstract: The present invention relates, in general, to prostate cancer. More specifically, the present invention relates to a method to diagnose prostate cancer in a, patient by detecting a PCA3 sequence, and more particularly a PCA3 RNA, the PCA3 sequence detected in a sample from the patient being specifically associated with prostate cancer. In a particular embodiment the method and kit enables an amplification of a PCA3 RNA through an exon-exon junction of a spliced PCA3 mRNA. The invention also related to methods and kits to detect such an amplified PCA3 RNA, using a probe which spans the amplified exonexon junction. The invention also relates to kits containing nucleic acid primers and kits containing nucleic acid primers and nucleic acid probes to diagnose, assess, or prognose a human afflicted with prostate cancer. In particular the methods and kits are designed to detect a PCA3 RNA  which lacks one intron or more, and in particular case is intron-less.
Patent CA-2532725-A1 (CA)
Title: Novel fusidic acid derivatives
Inventor: THORHAUGE JACOB
IPC: A61K31/575
Filed: 2004-07-09
Abstract: The present Invention relates to novel fusidic acid derivatives of general formula (I) wherein X represents halogen, trifluoromethyl, cyano, azido, alkyl, alkenyl or aryl, wherein. said alkyl, alkenyl or aryl are optionally substituted by one or more, same or. different substituents selected from the group consisting of alkyl, alkenyl, aryl, alkoxy, nitro, alkylthio, halogen, azido, trifluoromethyl and cyano; Y and Z both' represent hydrogen, or together with the C-17/C-20 bond form a double bond between C-17 and C-20, or together are methylene and form a cyclopropane ring in combination with C-17 and C-20; A represents a bond,. O, S or S(O); B represents C1-6 alkyl, C2-6 alkenyl, CI-6 acyl, C3-7cycloalkylcarbonyl or benzoyl, all of which are optionally substituted with one or more substituents selected from the group consisting of halogen, hydroxy, alkoxy, aryl, heteroaryl and azido, or, if A  represents a bond, B may also represent hydrogen; Q1 and 'Q2 independently represent. -CH2-, -C(O)-, -(CHOR)-, -(CHOR)-, -(CHSH)-, - (NH)-, -(CHNH2)- or -(CHW)-., wherein R represents CI-6alkyl and W represents halogen, cyano, azido or trifluoromethyi; Q3 represents -CH2-, -C(O)- or -CHOH-; G represents hydrogen, OH or O-CO-CH3; two bonds in the pentacyclic ring being depicted with full and dotted lines to indicate that either of the two bonds may be a double bond, in which case Y is absent and Z represents hydrogen; the bond between C-1 and C-2 being either a single or a double bond; and pharmaceutically acceptable salts and easily hydrolysable esters thereof, to pharmaceutical compositions comprising said derivatives, as well as to their use in therapy.
Patent CA-2532835-A1 (CA)
Title: Surface acoustic wave sensor or identification device with biosensing capability
Inventor: HUNT WILLIAM D
IPC: G01N27/327
Filed: 2006-01-13
Abstract: A surface acoustic wave sensor or identification device has a piezoelectric material, and an interdigitated transducer (IDT) input/output mounted on the piezoelectric material for receiving a radio frequency (RF) signal and propagating a corresponding surface acoustic wave along a surface of the piezoelectric material. An IDT finger electrode array is mounted on the piezoelectric material and is operable to communicate with the IDT input/output for transmission of a modified RF signal from the device. The IDT finger electrode array has at least one finger electrode segment whose propagating characteristics are controlled to control the nature of the modified RF signal. A biolayer is mounted on the piezoelectric material and is associated with the finger electrode segment, and a fluidic chamber is associated with the biolayer. In use, the fluidic chamber contains fluid which, if a predetermined substance to be sensed or detected is present, operates to modify the biolayer which in turn controls the nature of the modified RF signal.
Patent CA-2532850-A1 (CA)
Title: Gripping and positioning tool for molding machine
Inventor: BATTAGLIA ROBERT
IPC: B23Q7/04
Filed: 2006-01-13
Abstract: A gripping and positioning tool to properly position elements into an open mold of a molding machine is described herein. The tool includes a base that receives the element and that may be moved along three orthogonal axes and tilted in two directions with respect to a fixed plate mounted to an assembly. Furthermore, the tool includes graduated scales to determine the degree of tilting, and fasteners to lock in place the gripping and positioning tool once the proper adjustment for positioning is made.
Patent CA-2538370-A1 (CA)
Title: Lined balloon mounted stent
Inventor: LOTFY WAEL MOHAMED NABIL
IPC: A61F2/07
Filed: 2003-11-22
Abstract: This invention is concerned with a lined inflatable and dilatable stent (the stent is dilatable and its lining is either inflatable or dilatable) that wi ll be introduced inside vessels to control the blood (or other fluids) flow.</S DOAB>
Patent CA-2538484-A1 (CA)
Inventor: STAHL RAINER
IPC: A01H5/10
Filed: 2004-09-02
Abstract: The invention relates to a novel endosperm-specific plant promoter and the production and use thereof, preferably in cultivated plants.
Patent CA-2540814-A1 (CA)
Inventor: DUTRA HERBERTO
IPC: B60N3/10
Filed: 2006-03-21
Abstract: Adapters are provided for stable holding of non-cylindrical multi-sided food containers in beverage container receptacles, and also packaged food products integrating such adapters.
Patent CA-2542594-A1 (CA)
Inventor: STANSBY PETER KENNETH
IPC: F03B13/14
Filed: 2004-10-15
Abstract: Apparatus for extracting energy from waves comprises a float device coupled to a shaft such that vertical movement of the float devices drives the shaft.  Movement of the float device is generated by the wave motion, and the mass of the float device is such that its natural frequency of vertical oscillation is substantially resonant with the frequency of a sea wave. The mass of the float device can be adjustable to achieve this.
Patent CA-2543654-A1 (CA)
Inventor: KOLMES NATHANIEL
IPC: D02G3/44
Filed: 2004-10-26
Abstract: A composite cut-resistant yam is provided that has no high-performance fibers present and has wire only in the core, yet is comparable in cut-resistance characteristics, the yam containing a core of at least one fiberglass strand and at least one wire strand, either parallel or twisted about one another, and at least one cover strand made from non-metallic non-high performance fiber, along with fabric made therefrom, and protective articles and garments made from the fabric.
Patent CA-2549277-A1 (CA)
Inventor: ISLAM M KHALEDUL
IPC: H04W4/90
Filed: 2003-12-18
Abstract: Herein are disclosed an apparatus and method of explicit indication of call from emergency call centre. The method includes the steps of forming an emergency signal in relation to the mobile station terminated call; sending the emergency signal to the mobile station on behalf of the emergency call centre; and detecting the emergency signal at the mobile station. The apparatus includes emergency signal forming means for forming an emergency signal in relation to the mobile station terminated call; emergency signal sending means for sending said emergency signal to the mobile station on behalf of the emergency call centre; and emergency signal detecting means for detecting said emergency signal at the mobile station. A global emergency call information record is disclosed for use in cdma2000 type networks and the like. The apparatus and method may apply to other networks.
Patent CA-2551317-A1 (CA)
Inventor: GILLES JEAN GUY G
IPC: C12N5/12
Filed: 2006-07-12
Abstract: A monoclonal antiidiotypic antibody (Ab1), against a human antibody (Ab2) that inhibits factor VIII (F8) and is directed to the A2 domain of F8, is new. Independent claims are included for: (1) a stable cell line that produces Ab1; (2) hybridoma 30D1 (CNCM I-3450); (3) a DNA fragment of 461 base pairs (bp; SEQ ID NO: 1), encoding the variable region of the heavy chain of Ab1; and (4) a DNA fragment of 431 bp (SEQ ID NO: 2), encoding the variable region of the light chain of Ab1. ACTIVITY : Hemostatic. No details of tests for hemostatic activity are given. MECHANISM OF ACTION : Inactivation of inhibitory autoantibodies against F8.
Patent CA-2555769-A1 (CA)
Inventor: GRAY THOMAS A
IPC: G06Q10/00
Filed: 2006-08-10
Abstract: A system for resolving conflicts between personal and shared space policies, comprising a location manager for monitoring location of users, each of the users being represented by a user agent for receiving session requests in accordance with user specified personal policies, a common proxy for receiving location data for the users from the location manager and in response creating a list of users at each location, and a space proxy associated with an owner of each location for enforcing space policies specified by the owner such that upon receipt of a session request with a user specified personal policy that conflicts with one of the space policies then rejecting the session request.
Patent CA-2555812-A1 (CA)
Title: 3-3-di-substituted-oxindoles as inhibitors of translation initiation
Inventor: CHEN HAN
IPC: C07D209/34
Filed: 2005-02-11
Abstract: Compositions and methods for inhibiting translation using 3-(5-tert-Butyl-2-Hydroxy~phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using 3-(5-tert-butyl-2-hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are described.
Patent CA-2556796-A1 (CA)
Title: Milieu exempt de produit animal et procede de purification d'une toxine botulinique
Inventor: WANG PING
IPC: C12N9/64
Filed: 2005-03-03
Abstract: procédé et systèmes chromatographiques destinés à purifier une toxine botulinique à partir d'un milieu de fermentation APF(Animal protein free/exempt de protéines animales).
Patent CA-2557215-A1 (CA)
Title: Tetracycline derivatives for the treatment of ocular pathologies
Inventor: PEYMAN GHOLAM A
IPC: A61K31/573
Filed: 2005-02-25
Abstract: Formulations and methods useful to reduce ocular neovascularization (new blood vessels in the cornea, retina, conjunctiva, and/or choroid) are disclosed.  According to the invention the formulation will include tetracycline or a derivative thereof including chemically modified tetracyclines (CMT) which inhibit matrix metalloproteinase (MMP) activity at a substantially neutral pH  in a pharmaceutically acceptable form suitable for delivery to the eye in an amount and for a duration sufficient to reduce ocular neovascularization.  According to the invention the formulations are preferably in pharmaceutically acceptable formulations for topical ocular application, ocular injection, or ocular implantation, and may be contained in liposomes or slow release capsules.
Patent CA-2558249-A1 (CA)
Title: Substituted urea and carbamate, phenacyl-2-hydroxy-3-diaminoalkane, and benzamide-2-hydroxy-3-diaminoalkane aspartyl-protease inhibitors
Inventor: HOM ROY
IPC: A61K31/445
Filed: 2005-03-09
Abstract: The invention relates to acetyl 2-hydroxy-1,3-diaminospirocyclohexanes and derivatives thereof that are useful in treating at least one disease, disorder, and condition associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and condition associated with abnormal deposition of A-beta protein.
Patent CA-2560578-A1 (CA)
Inventor: MYREX LEE
IPC: B60R9/06
Filed: 2006-09-21
Abstract: A cargo carrier having a hitch sleeve on its bottom and legs with wheels on its sides. A hitch shaft is inserted into a trailer hitch on a vehicle and the hitch sleeve fits over the hitch shaft. The legs have an internal screw type jack mechanism to raise and lower the cargo carrier to place the hitch sleeve over the hitch shaft, and to raise the legs so that the vehicle can transport the cargo carrier on the hitch shaft without having to remove the legs. The wheels allow the cargo carrier to be portable when not connected to the vehicle and allow the hitch sleeve to be aligned with the hitch shaft to facilitate insertion of bolts through the hitch sleeve and hitch shaft, thereby fastening the cargo carrier to the hitch shaft. The legs can be rotatably mounted to the cargo carrier to provide additional clearance of the legs above the ground by rotating them, once the cargo carrier hitch sleeve is connected to the hitch shaft inserted in the vehicle trailer hitch.
Patent CA-2561105-A1 (CA)
Title: Structure d'arroseur multifonctionnel
Inventor: LO SHUN NAN
IPC: B05B3/02
Filed: 2006-09-26
Abstract: Une structure d'arroseur multifonctionnel comprenant un moteur hydraulique ayant un siège de sortie et un couvercle supérieur monté sur un côté d'extrémité supérieure, et deux sièges de réglage et un siège d'alimentation en eau assemblés sur un côté d'extrémité inférieure. Le côté d'extrémité inférieure du moteur hydraulique présente une rainure de guidage avec un trou restrictif pour l'extension d'un axe de commutation à travers celle-ci. Le siège de sortie comporte une chambre de décharge d'eau avec barrières multiples s'étendant sur celle-ci correspondant à une roue du moteur hydraulique, et un orifice de guidage central s'étendant obliquement et correspondant à une buse de pulvérisation comportant plusieurs nervures de guidage de l'eau s'étendant obliquement vers la même direction dans celle-ci. Par conséquent, les barrières du siège de sortie et les nervures de guidage de l'eau de la buse de pulvérisation sont utilisées pour correspondre à la direction de l'écoulement de l'eau de sorte que la décharge de l'eau peut être facilement commutée pour éjecter soit dans un jet plus direct et puissant en forme de colonne ou un jet plus étendu.
Patent CA-2563581-A1 (CA)
Inventor: SALA DARIO
IPC: A23G1/46
Filed: 2006-10-12
Abstract: Method for the preparation and distribution of a hot chocolate drink, wherein a dose of the liquid which forms the drink is heated to a predetermined temperature and a dose of a preparation containing chocolate is dispersed in the dose of heated liquid, wherein the dose of liquid is heated by making a flow of steam with a constant flow rate flow for a predetermined time into a flow of the said liquid which forms the drink, which also has a constant flow rate. The method can advantageously be implemented by a device comprising a source of water vapour (1), a source (5,6) of liquid for the formation of the drink, a distributor proportioning device (2) for a preparation containing chocolate, and a chamber (3) for mixing this preparation with the liquid for formation of the drink. The device includes a pipe (7) for supply of the liquid for formation of the drink, between the said source of liquid (5,6) and the said mixing chamber (3), pumping means (8) and calibrated choke means (9) which are disposed on this pipe (7) and generate a flow of liquid with a predetermined constant flow rate, a pipe (10) to supply steam between the source of steam (1) and a point of confluence (11) inside the said pipe (7) to supply the liquid for formation of the drink, disposed between the said calibrated choke means (9) and the said mixing chamber (3), the said pipe (10) for supply of the steam being provided with means for interception (12) and calibrated choke means (13) which can determine a flow of steam with a predetermined constant flow rate.
Patent CA-2565228-A1 (CA)
Title: Uniform delivery of compositions
Inventor: COMBS MARY JANE
IPC: D06F58/20
Filed: 2005-05-06
Abstract: A device for depositing benefit composition n a fabric article drying appliance, the device comprising : a pump, the pump comprising; a) a conduit wherein the conduit includes an inlet and a discharge; and b) a nozzle having one or more orifices connected to the discharge of the conduit; wherein the inlet of the conduit is in communication with a source of benefit composition so as to dispense the benefit composition through the conduit from the source of benefit composition of the nozzle whereby the benefit composition is dispensed from the nozzle into the fabric article drying appliance whereby the benefit composition has a mean droplet size of from about 100 microns to about 1000 microns and wherein the cone angle formed by the benefit composition that is discharged from the nozzle is between about 35ae and about 150ae.