baber/WOPTO huggingface dataset:
Patent WO-2020201211-A1 (WO)
Title: Single crystal composite synthetic diamond material
Inventor: EDMONDS ANDREW MARK
IPC: C30B25/02
Filed: 2020-03-30
Abstract: A method of forming a diamond composite body and the diamond composite body. A first single crystal diamond body is provided, which contains nitrogen and has a uniform strain such that over an area of at least 1x1 mm, at least 90 percent of points display a modulus of strain-induced shift of NV resonance of less than 200 kHz, wherein each point in the area is a resolved region of 50 µm 2 . The first single crystal diamond body is treated to convert at least some of the nitrogen to form at least 0.3 ppm nitrogen-vacancy, NV - , centres. A a CVD process is used to grow a second single crystal diamond body on a surface of the first single crystal diamond body. The second single crystal diamond body has an NV -  concentration less than or equal to 10 times lower than the NV -  concentration in the first single crystal diamond body.
Patent WO-2020201513-A1 (WO)
Title: Electromagnetic cavity able to support tamm modes
Inventor: MANGENEY JULIETTE
IPC: G02B5/00
Filed: 2020-04-03
Abstract: An electromagnetic cavity (10, 20, 30, 40, 60) able to support Tamm modes and possessing a resonant frequency in the THz domain, comprising: - an interference mirror that is reflective in the THz domain, this mirror consisting of a stack (7) of dielectric layers comprising an alternation, in a z-direction, of two different layers, a layer (2) called the high-refractive-index layer and a layer (4) called the low-refractive-index layer, the index of the low-refractive-index layer being lower than that of the high-refractive-index layer, and being manufactured by mechanically stacking layers or by joining dielectric layers to one another. - an upper metal layer (5) deposited on or added to an upper dielectric layer of said interference mirror so as to form a structure that supports at least one Tamm mode in the THz domain, the upper metal layer (5) being structured so as to form an antenna possessing a resonant frequency equal to that of the electromagnetic cavity.
Patent WO-2020208083-A1 (WO)
Title: Novel psma specific binding proteins for cancer diagnosis and treatment
Inventor: BOSSE-DOENECKE EVA
IPC: A61K38/17
Filed: 2020-04-08
Abstract: The present invention relates to new binding proteins that are specific for prostate specific membrane antigen (PSMA). The invention further refers to PSMA binding proteins that further comprise a diagnostically or therapeutically active component. Further aspects of the invention cover the use of these PSMA binding proteins in medicine, for example, in diagnosis and therapy of cancer associated with PSMA expression.
Patent WO-2020225255-A1 (WO)
Inventor: JORDAN OLIVIER
IPC: A61P31/10
Filed: 2020-05-05
Abstract: The invention relates to a bio-conjugate comprising a chitosan derivative coupled to antimicrobial peptides (AMPs) for use in the treatment or prevention of microbial infections such as wound healing. The invention also provides a nanoparticles formulation or a gel/hydrogel formulation or a lyophilized foam formulation comprising the bio-conjugate of the invention.
Patent WO-2020239416-A1 (WO)
Inventor: LIU FENG
IPC: G09B9/00
Filed: 2020-05-11
Abstract: Method and server for supporting generation of scenarios for testing autonomous driving and/or advanced driver assistance system (AD/ADAS) functionality for real world vehicles. A server (101; 500) provides (301) a virtual environment (200) simulating an environment relevant for operation of vehicles having said AD/ADAS functionality and in which is operating: fully computer controlled movable virtual objects (230a-c), human controlled movable virtual objects (220a-c) and at least one virtual AD/ADAS vehicle (210) operating according to said AD/ADAS functionality. The server (101; 500) allows devices (101-103) to remotely connect to the server (105; 500) and users of said devices (101-103) to, via user interfaces of the devices (101-103), control said human controlled movable virtual objects (220a-c), respectively, in the virtual environment (200), and thereby cause generation of scenarios that said at least one virtual AD/ADAS vehicle (210) is subjected to.
Patent WO-2020234328-A1 (WO)
Inventor: CUSCUNA DINO
IPC: A61B1/01
Filed: 2020-05-20
Abstract: A steerable catheter comprises a transducer that is situated at a flexible distal end, and is coupled to the handle of the catheter via an insertion tube. The flexible distal end is controlled by a plurality of articulation pull-cables that extend from an articulation control device in the handle to the far end of the distal end, such that when one articulation pull-cable is pulled, and the opposing articulation pull-cable is slackened, the flexible distal end bends in the direction of the tensioned articulation pull-cable. To minimize pull-resistance over time, while still providing insertion-tube flexibility, inserts having pull-cable lumens are situated in the insertion tube to isolate each articulation pull-cable from each other, and from other cables that couple the transducer to the handle.
Patent WO-2020260282-A1 (WO)
Title: Agencement d'aspiration d'outil de serrage
Inventor: WALLGREN CARL JOHAN ERIK
IPC: B25B21/00
Filed: 2020-06-23
Abstract: La présente invention concerne un tournevis électrique (10) comprenant un boîtier (11). Le boîtier (11) renferme un moteur (12) et une broche (15) d'entraînement d'embout au niveau d'une extrémité avant permettant d'entraîner un embout (17). Le tournevis électrique peut, au niveau de l'extrémité avant, être relié à un adaptateur d'aspiration (16) ayant une fonctionnalité de capture de vis par laquelle une vis à monter est mise en prise avec l'embout (17). Le tournevis électrique (10) comprend en outre un capteur de vide intégré dans le boîtier (18) conçu pour détecter la pression sub-atmosphérique dans l'adaptateur d'aspiration (16).
Patent WO-2021009282-A1 (WO)
Inventor: GRIFFINI GIANMARCO ENRICO
IPC: C23C14/02
Filed: 2020-07-16
Abstract: The present invention refers to a process of metallization of plastic substrates by means of physical vapor deposition (PVD) which comprises the chemical activation of the substrate, the coating thereof by means of a primer and the subsequent deposition of a metal layer. The invention further relates to the metallized plastic substrates obtainable according to the process.
Patent WO-2021013752-A1 (WO)
Title: Cartridge for dispensing a material
Inventor: MARIE OLIVIER
IPC: A61M5/31
Filed: 2020-07-17
Abstract: This cartridge (1), intended for the dispensing of a material, comprises: - a sleeve (2) having a longitudinal axis (X-X') and comprising a distal wall (22) provided with a dispensing hole (23); - a barrel (3) defining a chamber (35) configured to receive the material, the barrel (3) comprising a proximal open end and a breakable distal wall (39) at its distal end, the barrel (3) being configured to move in the sleeve (2) along the longitudinal axis (X-X') between a first position, in which the distal wall (39) of the barrel (3) is at a distance (e 1 ) from the distal wall (22) of the sleeve (2), and a second position, in which a sealing portion of the distal wall (39) of the barrel (3) is in contact with an inner surface of the distal wall (22) of the sleeve (2); - a piston (4, 5) configured to seal the chamber (35) of the barrel (3), the piston (4, 5) comprising a plate (47) configured to move in sealing engagement in the chamber (35) of the barrel (3); - wherein the sleeve (2) comprises an internal piercing element (29) in the vicinity of the dispensing hole (23), the piercing element (29) being configured to break the distal wall (39) of the barrel (3) upon transition of the barrel (3) from the first position to the second position; and - the sleeve (2) comprises an annular cavity (24) around the piercing element (29), the annular cavity (24) being delimited peripherally by a beveled inner surface complementary to a corresponding beveled outer surface of the barrel (3).
Patent WO-2021032381-A1 (WO)
Inventor: REINDL JOHANNES
IPC: B60K35/00
Filed: 2020-07-17
Abstract: A display system for a vehicle is proposed, wherein the display system has an output unit for displaying image contents for a user and an input unit for inputting operator control actions for the image contents. The display system has a detection unit which is configured to detect a sitting position of the user in the vehicle, and a processing device, wherein the processing device is configured to determine an available action space on the basis of the sitting position and to adapt the image content to be output and/or the action radius of the user on the basis of the available action space.
Patent WO-2021018791-A1 (WO)
Title: Method and an apparatus for dry processing hot coal and coke
Inventor: BALON THOMAS HAMILTON JR
IPC: C10L9/08
Filed: 2020-07-24
Abstract: An apparatus for handling hot coal is provided, comprising - a cooling structure arranged to receive coal from a process chamber and to cool the coal in an atmosphere impeding ignition; and - a pneumatic conveyor system arranged to move coal by air pressure; wherein the cooling structure is configured to cool the coal to a surface temperature allowing the pneumatic conveyor system to convey the coal across a predetermined distance without the coal igniting.
Patent WO-2021048251-A1 (WO)
Inventor: SCHÄFER DURDU
IPC: C01G25/00
Filed: 2020-09-10
Abstract: L'invention concerne un procédé de production d'oxydes mixtes de lithium-zirconium au moyen d'une pyrolyse par pulvérisation à la flamme, des oxydes mixtes pouvant être obtenus par ce procédé et leur utilisation dans des batteries au lithium-ion.
Patent WO-2021063967-A1 (WO)
Title: Novel substituted 6,7-dihydro-5h-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof
Inventor: BOISNARD SABINE
IPC: C07D413/12
Filed: 2020-09-29
Abstract: The present invention relates to a compound of the formula (I) wherein Ar represents a phenyl or a 6-membered heteroaryl group, R1 and R2 represent independently a hydrogen atom or a deuterium atom, R3 represents (1) a -COR4 group, (2) a -BOR5OR6 group, (3) a -X-Z group, (4) a (C 1 -C 6 )alkyl group or a (C 1 -C 6 )alkenyl group, (5) a -X-S(O) n (R7) p (R8) q  group, (6) a halogen atom, a -NH 2  group or a -CN group, (7) a -O-R11 group, (8) a -NH-COR9 group, (9) a -C(=NH)NHOH group, (10) a -NH-C(NH)-R9' group, or (11) a -NHCOCOOR12 group or a -NHCOCONR12'R12'' group, X represents a bond, a -NH- group, a -CONH- group or a -CO- group, Z represents a 4 or 5-membered cycloalkyl, a 4 or 5-membered heterocylcloalkyl group, a 4 or 5-membered heteroaryl group or a phenyl group or a pharmaceutically acceptable salt thereof. The present invention further relates to a medicament comprising said compound of formula (I) and to said compound of formula (I) for use as an inhibitor and degrader of estrogen receptors.
Patent WO-2021074239-A1 (WO)
Inventor: KURT FABIENNE
IPC: C12P39/00
Filed: 2020-10-14
Abstract: The present invention provides utilizations and methods to increase production of butyrate by a consortium of living bacteria. The invention also relates to pharmaceutical compositions that comprise (i) at least one bacterial strain producing lactate, (ii) at least one bacterial strain consuming lactate, (iii) at least one bacterial strain producing butyrate and (iv) butyrate.
Patent WO-2021104819-A1 (WO)
Title: Dispositif de mesure et procédé pour déterminer les propriétés d'un matériau à extruder lors de la mise en œuvre d'un processus d'extrusion par vis
Inventor: HEUER HENNING
IPC: G01N29/02
Filed: 2020-11-04
Abstract: Dans un dispositif de mesure pour déterminer les propriétés d'un matériau à extruder lors de la mise en œuvre d'un processus d'extrusion dans une extrudeuse (7), au moins une vis extrudeuse (4) est montée de manière rotative dans un guide tubulaire (5) dans un cylindre (7) et est reliée à un entraînement rotatif. Le matériau (1) à extruder est introduit dans le guide tubulaire (5) au niveau d'une extrémité et est retiré sous la forme d'un matériau au fini extrudé au niveau d'une évacuation (6) disposée à l'opposé. De multiples premiers transducteurs acoustiques (3) sont disposés à des emplacements de mesure à des intervalles définis prédéterminés sur la paroi du guide tubulaire (5) le long de l'axe longitudinal de la vis extrudeuse (4), ils sont conçus pour la détection d'ondes sonores qui sont générées lors du processus d'extrusion par le processus d'extrusion en tant que bruits de traitement et/ou sont émises par un second transducteur acoustique (2), disposé au niveau d'une extrémité du guide tubulaire (5), dans la direction de l'axe longitudinal de la vis extrudeuse (4) et dans le matériau à extruder qui est transporté à travers une chambre de mélange présente dans le guide tubulaire.
Patent WO-2021089850-A1 (WO)
Title: Antibody variant combinations and uses thereof
Inventor: DE JONG ROB
IPC: C07K16/28
Filed: 2020-11-06
Abstract: The invention relates to combination therapy involving two or more antibodies, wherein the Fc regions of the two antibodies have been modified such that hetero-oligomerization between the antibodies is strongly favored over self-oligomerization when antibodies are bound to their corresponding target antigens and such that hetero-oligomerization-independent effector functions of one or both antibodies are eliminated or strongly reduced. The invention also relates to antibodies, compositions, and kits suitable for use in the combination therapy of the invention.
Patent WO-2021121862-A1 (WO)
Inventor: KRUSCH CLAUS
IPC: F23R3/00
Filed: 2020-11-20
Abstract: The invention relates to a ceramic heat shield tile (01) for use in a combustion chamber of a gas turbine. This tile has a hot side (02) and, opposite this, a cold side (03), which are connected to each other via two mutually opposite longitudinal edges (04) which each have at least one securing recess (06), and via two transverse edges (05). For fastening in a longitudinal direction, at least one fastening recess (07, 17) is provided on the cold side (03).
Patent WO-2021122991-A1 (WO)
Title: Systèmes d'emballage pour dispositifs d'administration de médicaments et kits d'emballage
Inventor: CANNAMELA MICHAEL
IPC: B65D75/36
Filed: 2020-12-17
Abstract: L'invention concerne divers systèmes d'emballage et kits d'emballage. Dans un mode de réalisation donné à titre d'exemple, l'invention concerne un système d'emballage qui comprend une base configurée pour recevoir un dispositif d'administration de médicaments ayant un corps de dispositif ayant un segment supérieur et un segment inférieur, et un actionneur. La base est configurée pour loger le dispositif d'administration de médicaments reçu dans son sein selon un angle non nul par rapport à un axe longitudinal de la base. La base comprend une cavité de retenue et une cavité de préhension adjacente à la cavité de retenue. La cavité de retenue est configurée pour créer un ajustement serré avec au moins une partie d'un segment supérieur d'un dispositif d'administration de médicaments reçu à l'intérieur de la base, et la cavité de préhension est configurée pour recevoir un segment inférieur d'un corps de dispositif et une partie d'un actionneur d'un dispositif d'administration de médicaments reçu à l'intérieur de la base.
Patent WO-2021148256-A1 (WO)
Title: Gehäuse mit einer druckausgleichseinrichtung
Inventor: KARAGÖZ HASAN-ÖZKAN
IPC: H05K5/06
Filed: 2021-01-08
Abstract: Die Erfindung betrifft ein Gehäuse (105) mit einer Druckausgleichseinrichtung (100) zum Ausgleich eines Drucks in einem mit der Druckausgleichseinrichtung (100) in Verbindung stehenden Innenraum (200) des Gehäuses (105) in Bezug auf eine Umgebung (300) des Gehäuses (105). Die Erfindung sieht vor, dass ein Grundkörper (125) und eine flexible Dichtlippe (120) eines Lippendichtungselements (115) eines Überdruckventils aus einem elastomeren Werkstoff einstückig ausgebildet und direkt in der Bohrung (205) in einer Gehäusewandung des Gehäuses (105) gehalten sind, wobei eine Dichtfläche (140), mit welcher die flexible Dichtlippe (120) zusammenwirkt, durch die radial innere Umfangsfläche der Bohrung (205) gebildet wird.
Patent WO-2021144315-A1 (WO)
Title: Conjugates of antibodies an immune cell engagers
Inventor: VAN GEEL REMON
IPC: A61K47/68
Filed: 2021-01-13
Abstract: The present invention concerns a process for preparing a multispecific antibody construct, comprising conjugating a functionalized antibody Ab(F) x  containing x reactive moieties F, wherein x is an integer in the range 1 – 10, and an immune cell-engaging polypeptide containing one or two reactive moieties Q, wherein the antibody is specific for a tumour cell and the immune cell-engaging polypeptide is specific for an immune cell, wherein the reaction forms a covalent linkage between the functionalized antibody and the immune cell-engaging polypeptide by reaction of Q with F. The invention further concerns the multispecific antibody constructs obtainable by the process according to the invention and medical uses thereof.
Patent WO-2021165154-A1 (WO)
Title: Connector
Inventor: WIKNER JAKOB
IPC: A42B3/06
Filed: 2021-02-12
Abstract: There is provided a connector (20) for connecting inner and outer layers of an apparatus, the connector comprising: a first attachment part (21) for attaching to one of the inner or outer layers; a second attachment part (22)for attaching to the other of the inner or outer layers; wherein: the first and second attachment parts are connected in such a way as to allow the first attachment part and second attachment part to move relative to each other when the inner and outer layers move relative to each other, and the first attachment part comprises: a first flange portion (211) adjacent a gap (214), said gap for accommodating a portion of said one of the inner or outer layers, said flange portion retaining said inner or outer layers within said gap, and wherein the first flange portion is substantially domeshaped.
Patent WO-2021180812-A1 (WO)
Title: Virtual machine perfect forward secrecy
Inventor: GREEN MATTHEW
IPC: G06F9/455
Filed: 2021-03-10
Abstract: Provided is a method, a computer program product, and a system for providing perfect forward secrecy in virtual machines. The method includes receiving a secure memory allocation function from an application, including a connection secret to be stored in memory. The method further includes allocating memory for the connection secret according to the memory size parameter and storing an entry relating to the connection secret in a secure database. The memory information includes a memory location and a memory size of the memory. The method also includes monitoring an operation state relating to the virtual machine. The method further includes receiving, from the application, a secure deallocation function relating to the connection secret and retrieving the memory information from the secure database. The method also includes deleting the connection from the memory and sanitizing the memory location logged by the memory information.
Patent WO-2021244787-A1 (WO)
Inventor: LAMMER-KLUPAZEK EWALD
IPC: F16B25/00
Filed: 2021-03-26
Abstract: Eine Gefälledämmungsschraube (1) zur einstellbaren Befestigung einer Dachbahn (2) auf einem Untergrund, insbesondere einem Stahlblech (3), die Gefälledämmungsschraube (1) aufweisend eine Bohrspitze (4) mit einer ersten Drehrichtung; anschließend an die Bohrspitze (4) ein Montagegewinde (7) mit einer zweiten Drehrichtung, die sich von der ersten Drehrichtung unterscheidet; anschließend an das Montagegewinde (7) ein erster gewindefreier Bereich (8); anschließend an den ersten gewindefreien Bereich (8) ein Justiergewinde (9) mit der ersten Drehrichtung, dessen Außendurchmesser größer ist als die Außendurchmesser des Montagegewindes (7) und der Bohrspitze (4); und anschließend an das Justiergewinde (9) eine Werkzeugaufnahme (10) sowie ein System (11) zur einstellbaren Befestigung einer Dachbahn (2) auf einem Untergrund mit einer Gefälledämmungsschraube (1) und einem Halteelement (12) und ein Verfahren zur einstellbaren Befestigung einer Dachbahn (2) auf einem Untergrund unter Verwendung eines derartigen Systems (11).
Patent WO-2021213834-A1 (WO)
Inventor: HOHLRIEDER MARTIN
IPC: A61F2/00
Filed: 2021-04-13
Abstract: Einrichtung umfassend einen Flüssigkeitsballon (1), eine mit dem Flüssigkeitsballon (1) über einen Schlauch (3) verbundene Pumpeinheit (5) zum Einpumpen von Flüssigkeit in den Flüssigkeitsballon (1) und zum Abpumpen von Flüssigkeit aus dem Flüssigkeitsballon (1), welche einen mit Flüssigkeit befüllbaren Aufnahmeraum (10) aufweist, dessen Volumen durch Bewegen eines Stellteils (11) der Pumpeinheit (5) mittels eines von einer Batterie (7) gespeisten Elektromotors (6) veränderbar ist, eine elektronische Kontrolleinheit (8) zum Kontrollieren des Elektromotors (6) und mindestens einen Drucksensor (20) zum Erfassen des Drucks der Flüssigkeit im Aufnahmeraum (10), dadurch gekennzeichnet, dass die Einrichtung im Weiteren einen Wegaufnehmer zur Erfassung der Position des Stellteils (11) aufweist. Bei einem Verfahren zum Einstellen eines Befüllungszustandes des Flüssigkeitsballons (1) wird das Volumen eines mit Flüssigkeit befüllten Aufnahmeraums (10) der Pumpeinheit (5) durch Bewegen eines Stellteils (11) der Pumpeinheit (5) mittels eines von einer Batterie (7) gespeisten Elektromotors (6) verändert, wobei von einer den Elektromotor (6) kontrollierenden Kontrolleinheit (8) ein Stellvorgang des Stellteils (11) durchgeführt wird. Der Stellvorgang umfasst eine Wegregelung des Stellteils (11) zum Anfahren einer SollPosition des Stellteils (11) und nach dieser Wegregelung eine Überprüfung, ob der Druck der Flüssigkeit im Aufnahmeraum (10) innerhalb eines zulässigen Befüllungs-Druckbereichs um den zweiten Befüllungsdruck liegt. Gegebenenfalls wird die Position des Stellteils (11) nachgestellt.
Patent WO-2021209519-A1 (WO)
Title: Method for determining an indication of an acuity level of a user
Inventor: GRONDIN ELIDIA
IPC: A61B3/032
Filed: 2021-04-14
Abstract: The invention relates to the field of computer implemented methods for determining an indication of an acuity level of a user and a corresponding computer program product and a device. In particular, the present invention relates to methods and devices to facilitate the performance of acuity tests in a decentralized manner while furthermore establishing a desired test accuracy irrespective of a particular type of device or display so as to determine an indication of an acuity level of a user in a reliable manner. Accordingly, a computer implemented method for determining an indication of an acuity level of a user (12) is suggested, comprising the steps of: performing an optical acuity test using a control unit (14) being in communication with a display (16) of a device (10), wherein the display (16) has a predefined resolution; and displaying the optical acuity test on the display (16) of the device (10), wherein the displayed optical acuity test comprises a graphical representation (20) comprising a discontinuity (22) and prompts the user (12) to identify said discontinuity (22) by providing a user response. The control unit (14) and the display (16) furthermore provide that the optical acuity test is adjusted by generating and displaying the discontinuity (22) based on the user response and based on anti-aliasing using one or more pixels of the display (16).