baber/WOPTO huggingface dataset:
Patent CA-2293472-A1 (CA)
Title: Preparation and uses of n-methylnitrone
Inventor: THERIOT KEVIN J
IPC: C07C239/10
Filed: 1998-06-12
Abstract: Oxidation of secondary amines with hydrogen peroxide and sodium tungstate is reported to give good yields of nitrones. However, when using dimethylamine in this manner, a considerable amount of N,N-dimethylformamide was produced as a co-product. To more selctively produce N-methylnitrone from dimethylamine, a two-step process is used which comprises (a) mixing together dimethylamine and a peroxidic compound, and subjecting the resultant mixture to reaction conditions effective to form a reaction mixture in which N,N-dimethylhydroxylamine has been formed; and (b) mixing together (i) reaction mixture from (a), (ii) a peroxidic compound, and (iii) a transition metal-containing oxidation catalyst, and subjecting the resultant mixture to reaction conditions effective to form a reaction mixture in which N-methylnitrone has been formed. Highest yields of N-methylnitrone are achieved by conducting step (b) at a pH in the range of 7 to 12, and at a temperature in the range of -10 to 100 ~C.
Patent CA-2294157-A1 (CA)
Inventor: NEWHOUSE THOMAS J
IPC: E04B2/74
Filed: 1998-06-18
Abstract: A molded fabric cover (10) with an integral undercut or inturned peripheral flange (14) for affixing the cover to the structure (22) to be treated. The covers have a conventional, decorative, woven polyester fabric (26) (of the type currently used in conventional office divider screen systems), or fabrics comprising other synthetic or natural fibers, bonded with adhesive (30) to a relatively stiff moldable non-woven polyester fiber backing (28). The covers are formed in a membrane or bladder (46) press in which a flexible membrane (46) presses the fabric and fiber composite against a form or mold (50) that includes an undercut edge (20) which, in cooperation with the press membrane, forms undercut flanges (60) about the periphery of the cover. The undercut or inturned flange may then be "snapped" over a corresponding mounting lip (24) on the structure to be treated.
Patent CA-2301533-A1 (CA)
Title: Balloons made from liquid crystal polymer blends
Inventor: FERRERA DAVID A
IPC: A61F2/958
Filed: 1998-09-04
Abstract: Balloons for use on medical devices such as catheter ballons are formed from polymer blend products which include a liquid crystal polymer (LCP), a crystallizable thermoplastic polymer, especially thermoplastic polyesters such as PET, and a compatabilizer.      The compatabilizer my be an ethylene-maleic anhydride copolymer, an ethylene-methyl acrylate copolymer, an ethylene-methyl acrylate copolymer, an ethylene-methyl acrylate-maleic anhydride terpolymer, an ethylene-methyl-methacrylic acid terpolymer, an acrylic rubber, and ethylene-ethyl acrylate-glycidyl methacrylate terpolymer or a mixture of two or more such polymers.
Patent CA-2303832-A1 (CA)
Title: Thrombin inhibitors
Inventor: NAYLOR-OLSEN ADEL M
IPC: A61K31/4409
Filed: 1998-09-25
Abstract: A compound which inhibits human thrombin and which has general structure (I), such as (II).
Patent CA-2303852-A1 (CA)
Title: Fish gelatin compositions containing a hydrocolloid setting system
Inventor: HE XIONGWEI
IPC: A23L29/281
Filed: 1998-11-04
Abstract: The invention concerns Gelatine compositions containing an additional setting system for the use in pharmaceutical, veterinary, food, cosmetic or other products like films for wrapping food, aspics or jellies, preferably for predosed formulations like soft or hard gelatine capsules wherein the gelatine used is of non-bovine and non-pig origin and preferably derived from fish, poultry or plant sources. Especially preferred are film compositions for hard gelatine capsules prepared from fish gelatine.
Patent CA-2306229-A1 (CA)
Inventor: AUER JOHANNES
IPC: C12N15/09
Filed: 1998-10-20
Abstract: L'invention concerne un procédé d'introduction d'un ADN étranger dans le génome d'une cellule cible par recombinaison homologue, ainsi que des constructions d'ADN pouvant être utilisées pour la recombinaison homologue.
Patent CA-2309568-A1 (CA)
Inventor: BEAVER JEFFREY L
IPC: B65D47/14
Filed: 2000-05-26
Abstract: A fluid dispensing closure which incorporates a dispensing valve to control fluid flow through the closure and a vent passageway to vent air into the container as necessary. The closure includes a dispenser spout offset from the axis of the closure and capable of mating engagement with a receiving container. The dispenser spout has a fluid passageway with a spring-biased ball valve seated therein. A vent passageway is also formed in the closure which includes a gravity loaded ball valve to close the vent passageway according to the position of the closure. A removable overcap sealingly encloses the dispenser spout and vent to capture any fluid leakage.
Patent CA-2309598-A1 (CA)
Inventor: KUWANO KAZUYOSHI
IPC: A61P11/00
Filed: 1998-11-09
Abstract: Preventives and remedies for diffuse lung diseases whereby apoptosis can be inhibited and thus favorable preventive/therapeutic effects can be established. These drugs contain apoptosis-inhibiting substances as the active ingredient. The above apoptosis-inhibiting substances include Fas antagonists and Fas-Fas ligand bond inhibitors such as Fas derivatives and anti-Fas ligand antibodies.
Patent CA-2309610-A1 (CA)
Inventor: ESTES BRADLEY T
IPC: A61F2/44
Filed: 1998-12-11
Abstract: A guide is disclosed for use in performing spinal surgery to prepare across a spinal disc and adjacent vertebrae an implantation space. The guide is associated with a computer controlled surgical navigation system employing an energy-detecting array to track positions of the guide in three dimensional space relative to a known reference point. The guide comprises a body for providing protected access to prepare across the spinal disc and into the adjacent vertebrae the implantation space. The body has a passage adapted to receive a bone removal device for forming the implantation space through the body. At least one electrically energizable energy emitter array is attached to the body for use in identifying the location of the guide relative to the adjacent vertebrae. A system and method for using the guide in spinal surgery are also disclosed.
Patent CA-2310299-A1 (CA)
Title: Method and apparatus for exchange of routing database information
Inventor: CAIN BRAD
IPC: H04L12/56
Filed: 2000-05-31
Abstract: A route table providing a list of pointers to checksum values computed across routes of interest to a particular protocol. A method of updating the route table when a route is changed and also updating the checksum values is further described.  Updates to the checksum value may be done using an exclusive OR process allowing for relatively fast, incremental updates to the checksum value.
Patent CA-2311048-A1 (CA)
Inventor: MURI JOHN I
IPC: A61B17/54
Filed: 2000-06-08
Abstract: A multipurpose handpiece for use with an abrasive material delivery system is disclosed wherein the handpiece includes channels for delivery and removal of an abrasive material applied to a patient's skin. The invention includes a multi-port applicator for selectively applying the abrasive material, said application of abrasive material suited for different areas of tissue such as stomach versus eye lids.  The present invention comprises a pair of tubings connected to a housing for delivery and vacuum removal of abrasive material, and a flow regulator disposed within the housing. Connected to the housing at an application end is a resurfacing applicator with a plurality of differing sized openings designed for different types of tissue. The present invention includes means for blocking the unused openings while permitting injection of the abrasive material through a selected opening. The blocking of the unused openings may be achieved by a shield or covers for each opening. The present invention is further adapted to stop the flow of the abrasive material while the openings are being changed, and means are provided for rotating the resurfacing applicator, and for aligning the resurfacing applicator opening with the injection port of the flow regulator for even and uninterrupted flow of material.
Patent CA-2314398-A1 (CA)
Title: Microarrays and microsystems for amino acid analysis and protein sequencing
Inventor: SHIPWASH EDWARD
IPC: C12Q1/68
Filed: 2000-08-10
Abstract: A method is described where the amino acyl-tRNA synthetase system is used to create very small devices for quantitative analysis of the amino acids in samples or in sequential or complete proteolytic digestions. The methods can be readily applied to the detection and/or quantitation of one amino acid by using only its cognate amino acyl-tRNA  synthetase and cognate tRNA. The basis of the method is that each of the 20 synthetases and/or a tRNA specific for a different amino acid is separated spatially or differentially labeled.  The reactions catalyzed by all 20 synthetases are monitored simultaneously. Each separately positioned synthetase or tRNA will signal its cognate amino acid. The synthetase reactions can be monitored using continuous spectroscopic assays. Alternatively, since elongation factor Tu;GTP  (EF-Tu;GTP) specifically binds all AA-tRNAs, the amino acylation reactions catalyzed by the synthetases can be monitored using ligand assays. Microarrays for amino acid analysis are provided. Additionally, amino acid analysis devices are integrated with protease digestions to produce miniaturized enzymatic sequenators capable of generating either N- or C-terminal sequence data and amino acid analyzers with integrated protein and peptide hydrolysis. The possibility of parallel processing of many samplers in an automated manner is discussed.
Patent CA-2315720-A1 (CA)
Title: Inhibition of p38 kinase activity using substituted heterocyclic ureas
Inventor: DUMAS JACQUES
IPC: A61P1/16
Filed: 1998-12-22
Abstract: This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases, other than cancer and proteolytic enzyme mediated diseases, other than cancer, and pharmaceutical compositions for use in such therapy.
Patent CA-2317032-A1 (CA)
Inventor: WINKLER STEVEN T
IPC: E21B43/12
Filed: 2000-05-31
Abstract: A rotating tag bar is positioned below a progressive cavity pump stator for supporting at least a portion of a rod string a rotor. A tubular housing is secured to the stator and is fitted with a rotatable platform. The platform blocks downward stretch of the rotor and then rotatably support the rotor on a thrust bearing. Thereby, rotor-imposed loads on the platform translate into tensile loads directed into the stator, which is suspended from tubing string, lessening the load on the rod string and thereby both reducing the need for extreme accuracy in rotor positioning and reducing rod string and tubing wear.  Optionally, a no-turn tool transmits load from the stator into the casing. In operation, the rotor is landed to contact the platform. The rotor is then lifted a distance less than the anticipated stretch so that when in operation, the rotor sets down on the platform and transfers at least a portion of the rod string load into stator.
Patent CA-2317295-A1 (CA)
Inventor: ZHU PENGFEI
IPC: H04B7/26
Filed: 2000-08-31
Abstract: A method for adjusting a protocol signal to be transmitted based on adjustments made to a detected protocol signal. The detected protocol signal carries adjustment information made to such signal to increase the likelihood of the signal being detected. The adjustment information is retrieved from the detected protocol signal and is used to adjust at least one characteristic of the protocol signal to be transmitted thereby also increasing the likelihood that such a signal (i.e., protocol signal to be transmitted) will be detected.
Patent CA-2318972-A1 (CA)
Inventor: DIPIETRO THOMAS C
IPC: C08L77/12
Filed: 1999-01-27
Abstract: Thermoplastic, non-water soluble, fluorescent pigments having improved lightfastness are provided which are suitable for coloring a variety of materials including plastics, particularly polyolefins, as well as paints, inks and textiles. The lightfast pigments of the present invention have several embodiments, the polyamide, polyamide ester and the polyester embodiments. They comprise copolymerized units of fluorescent dye and monomers such as dicarboxylic acids, polycarboxylic acids, diamines, polyamines, alkanolamines, carboxyalcohols, carboxyamines and difunctional and/or polyhydric alcohols. The fluorescent dye is reacted into, and covalently bound to the polymer backbone. The addition of an optional light stabilizer further enhances the lightfastness of the pigment. The invention also relates to a method of making such lightfast pigment.
Patent CA-2319888-A1 (CA)
Inventor: MARTIN ALLAN R
IPC: G06F7/52
Filed: 2000-09-18
Abstract: The invention pertains to an improved method for generating ALU instruction sequences for performing integer multiplication. The invention analytically helps to find an optimal sequence of shift, add and subtract instructions for performing integer multiplication by trying to add or subtract all powers of 2 less than the integer multiplier itself and then trying to factor evenly the resulting sum or difference by that power of 2 plus or minus one.  If each such resulting factor value factors by a power of 2, the corresponding factor set is a favorable one for generating an optimal ALU instruction sequence.
Patent CA-2321409-A1 (CA)
Inventor: SEZAKI ISAO
IPC: H04N5/45
Filed: 2000-09-28
Abstract: Circuit de génération de cadres d'image comprenant : un processeur de calcul de valeurs de coordonnées qui calcule la position de départ de cadre (X, Y), la position finale d'image (X, Y), la position finale de cadre (X, Y) en utilisant un signal de début de calcul comme signal d'activation, d'après des registres de position d'image (X, Y), des registres de taille d'image (X, Y) et des registres de taille de cadre qui sont écrits par l'intermédiaire d'un bus de données, le processeur permettant l'écriture de données de couleur de cadre dans un registre de couleur de cadre pour désigner la couleur de cadre par l'intermédiaire du bus de données ; et un circuit de sélection de cadre et d'image auquel sont entrés la position de départ de cadre (X, Y), la position finale d'image (X, Y), la position finale de cadre (X, Y), les registres de position d'image (X, Y), les données de couleurs de cadre, les données d'image, la position d'affichage horizontal et la position d'affichage vertical, le circuit sélectionnant les données d'image ou les données de couleur de cadre et sortant les données sélectionnées sous la forme de données d'affichage.
Patent CA-2322093-A1 (CA)
Title: Soft, transparent and processable thermoplastic polyurethane
Inventor: MASON ARTHUR W
IPC: C08G18/66
Filed: 2000-10-02
Abstract: A soft, transparent and processable thermoplastic polyurethane resin suitable in optical application is disclosed. The resin is the product of reacting a diisocyanate, a chain extender, and a mixture of polyether polyols. The mixture of polyether polyols comprise (A) a C4 polyether polyol and (B) a C2-C3 polyether polyol where the weight ratio A/B is in the range of about 85/15 to 15/85.
Patent CA-2322734-A1 (CA)
Title: Flame-retardant polyolefin-type resin composition, method for the preparation thereof, and flame retardant cables
Inventor: NAKANISHI KOJI
IPC: C08L83/06
Filed: 2000-10-10
Abstract: A flame-retardant polyolefin-type resin composition comprising (A) 100 weight parts polyolefin-type resin, (B) 30 to 200 weight parts powder of a hydrated metal compound, and (C) 0.01 to 50 weight parts branched organopolysiloxane with average unit formula RaSiO(4-a)/2 where each R is a selected from the group consisting of monovalent organic groups selected from the group consisting of C1 to C12 alkyl and C6 to C12 aryl and hydroxyl, wherein aryl constitutes from 50 to 100 mole% of the total monovalent organic groups and the hydroxyl content in each molecule is from 1 to 10 weight%, a is a number from 0.75 to 2.5, and the organopolysiloxane contains at least one RSiO3/2 siloxane unit in each molecule, where R is as previously described. The composition is useful as a flame-retardant coating on electrical cables.
Patent CA-2324215-A1 (CA)
Inventor: SCHUY WERNER
IPC: C01G49/06
Filed: 1999-03-17
Abstract: The invention relates to a method for producing iron oxide pigments from the waste acid resulting from the production of titanium dioxide according to the sulfate process. The invention is characterized in that in a first step the sulphuric acid contained in the waste acid is partially neutralized with metallic iron compounds and/or iron compounds and possibly neutralized further with another alkaline compound. The precipitate containing Ti, Al, Cr and V compounds is separated from the reaction product obtained in this way. From the resulting iron-sulfate-containing solution an iron oxide yellow pigment or a black iron oxide pigment is precipitated by addition of alkaline compounds and an oxidizing agent. Both pigments can be converted by calcination into an iron oxide red pigment.
Patent CA-2324753-A1 (CA)
Inventor: CAPORELLI AUGUSTO JOSE
IPC: A61J7/04
Filed: 2000-10-27
Abstract: The present invention relates to a device which comprises three elements superposed among them, one as a fixed base, with a quadrant of twenty four hours on which an indicator cursor is central and rotatively applied, as the hand of a clock with respect to this quadrant, and that is provided of an own sectional quadrant which limits the mentioned periods with which an index of the third element is operatively associated, build under the shape of a dial, and also central an rotatively applied with respect to the others and provided of complementary indicators directly associated to the quadrant of twenty four hours through cooperative holes of the body of the cursor.
Patent CA-2325629-A1 (CA)
Title: Crystalline forms of 1s-[1alpha (2s*,3r*), 9alpha]-6, 10-dioxo-n- (2-ethoxy-5 -oxo-tetrahydro-3 -furanyl) -9-[[(1-isoquinolyl) carbonyl]-amino] octahydro-6h -piridazino[1, 2-a][1,2] diazepin- 1-carboxamide
Inventor: ROGNON VALERIE
IPC: A61P25/00
Filed: 1999-04-07
Abstract: The invention concerns novel crystalline forms of 1S-[1alpha(2S*, 3R*),9alpha]-6, 10-dioxo-N- (2-ethoxy-5 -oxo-tetrahydro-3 -furanyl)-9-[[( 1-isoquinolyl) carbonyl]-amino] octahydro-6H -piridazino[1, 2-a][1,2]diazepin-1 -carboxamide, anhydrous (form A) and hydrated (form B), the method for preparing them, their use as medicine and the pharmaceutical compositions containing them.
Patent CA-2329482-A1 (CA)
Title: Recombinant antibodies specific for tnf-.alpha.
Inventor: ADAIR JOHN R
IPC: C12N15/11
Filed: 1991-12-20
Abstract: Recombinant, in particular humanised, e.g. humanised chimeric and CDR-grafted humanised, antibody molecules having specificity for human TNF.alpha., are provided for use in diagnosis and therapy. In particular the antibody molecules have antigen binding sites derived from murine monoclonal antibodies CB0006, CB0010,hTNF.alpha. or 101.4. Preferred CDR-grafted humanised anti-hTNF.alpha. antibodies comprise variable region domains comprising human acceptor framework and donor antigen binding regions and wherein the frameworks comprise donor residues at specific positions. The antibody molecules may be used for therapeutic treatment of human patients suffering from or at risk of disorders associated with undesirably high levels of TNF, in particular for treatment of immunoregulatory and inflammatory disorders of septic, endotoxic or cardiovascular shock.
Patent CA-2330201-A1 (CA)
Title: Method of operating or constructing a geartooth sensor
Inventor: LAMB WAYNE A
IPC: G01D5/244
Filed: 2001-01-03
Abstract: A geartooth sensor utilizes an algorithm for establishing an adaptive threshold for the switch point of the sensor to minimize drift in the point at which the sensor output changes in relation to the target features it is tracking. The algorithm utilizes measured waveform peak and average outputs and applies a separate empirically derived constant to each value to quickly obtain the major portion of the adaptive threshold value from the product of the first constant and the peak output, and to refine the threshold value further with the product of the second constant and the average output.
Patent CA-2330223-A1 (CA)
Title: Expression cassette and plasmid for strong constitutive gene expression and the use thereof
Inventor: CHO JEONG WOO
IPC: C12N9/10
Filed: 2001-01-25
Abstract: The present invention provides isolated nucleic acid constructs comprising a plant strong constitutive promoter operably linked to a heterologous nucleic acid which encodes a desired polypeptide in transgenic plant tissues. Said constructs are capable of conferring the highest expression of the desired polypeptides in plant root tissue and plant leaf tissue when used as a construct for a heterologous coding sequence in chimeric gene. After any chimeric gene can be linked to said construct, the resulting vector can be introduced into plant tissues, thereby intentionally modifying plants and making the resulting plants produce foreign substances therein.
Patent CA-2335192-A1 (CA)
Inventor: KOZAK VINCENT J
IPC: E21B47/12
Filed: 2001-02-09
Abstract: The invention relates to a continuous rod system for downhole operations. In particular, the invention relates a continuous rod having a groove along the exterior of the rod which retains a data transmission wire within the groove. The rod construction in accordance with the invention simplifies the incorporation of a data transmission wire within a continuous rod.
Patent CA-2337016-A1 (CA)
Title: Article absorbant jetable comportant un element de prise en charge des matieres fecales
Inventor: MULLER JORG
IPC: A61F13/53
Filed: 1999-07-23
Abstract: Cette invention a trait à un article absorbant jetable dont la feuille de base est pourvue d'un élément de prise en charge des matières fécales. Cet élément comporte un support diffuseur et une feuille en fibres. Cette dernière est pourvues de parties d'ancrage dans le support diffuseur situées sur des parties de connexion séparées les unes des autres ainsi que de parties cintrées faisant saillie à partir du support entre les emplacements de connexion.
Patent CA-2339896-A1 (CA)
Inventor: WORCH ANDREAS
IPC: G06F15/173
Filed: 2001-03-02
Abstract: An internal computer network comprising a plurality of electronic computer subsystems for forming a multiprocessor system or mainframe computer, wherein a plurality of plug-in places for central processing units (CPUs 11) are disposed on a circuit board. The CPUs (11) are connected through internal busses (23) to backplanes (22a, 22b, 22c, 22d, 22e). The backplanes (22a, 22b, 22c, 22d, 22e) in turn connect slave cards (17, 18, 19) to a master card.
Patent CA-2339970-A1 (CA)
Title: Nematicidal pyrazoles
Inventor: OTSU YUICHI
IPC: A01N47/38
Filed: 1999-08-03
Abstract: Novel pyrazoles of formula (I) wherein R1 represents halogen, C1-6 alkyl, C1-5 haloalkyl, C2-6 alkoxy, C1-4 alkylthio, C2-5 alkenyloxy, C3-5 alkynyloxy, C2-6 (total carbon number) alkoxyalkyl), C2-6 (total carbon number) alkylthioalkyl, C1-5 haloalkoxy, C2-6 (total carbon number) alkoxyalkoxy, hydroxy or optionally substituted phenyl, R2 represents hydrogen, halogen, C1-5 alkyl, C2-6 (total carbon number) alkoxyalkyl, C2-6 (total carbon number) alkylthioalkyl, C2-6 (total carbon number) alkylsulfinylalkyl, C2-6 (total carbon number) alkylsulfonylalkyl or C1-5 haloalkyl, R3 represents hydrogen, C1-5 alkyl, -COR4, COOR5, CH(OR6)2 or CH2Si(R7)3, R4 represents C1-10 alkyl, C1-6 haloalkyl, C2-6 alkenyl, optionally substituted C3-6 cycloalkyl, C2-6 (total carbon number) alkoxyalkyl, C22-6 (total carbon number) alkylthioalkyl, optionally substituted phenyl, C1-6 haloalkyl, alkylamino, di-(C1-6 alkyl)amino or optionally substituted phenylamino, R5 represents C1-7 alkyl, R6 and R7 represent C1-6 alkyl, and n is 1, 2 or 3, and when n is 2 or 3, the corresponding number (n) of R1 radicals may be the same or different, processes for preparing these compounds and their use as nematicides and anthelmintics.