baber/WOPTO huggingface dataset:
Patent HK-59889-A (HK)
Title: A rhodium catalyst and its application
Inventor: VILLAX JOAO EMERICO
IPC: B01J/
Filed: 1989-07-27
Abstract: The new compound bis(triphenylphosphine)hydrazinomethoxyrhodium (I) is a catalyst for the stereo-specific hydrogenation of demethyl-6-deoxy-6-methylene-5-hydroxytetracycline to  alpha -6-deoxy-5-hydroxy-tetracycline.
Patent HK-68295-A (HK)
Title: Process for the preparation of cephalosporin derivatives
Inventor: PRAGER BERNHARD CHRISTIAN
IPC: C07D501/56
Filed: 1995-05-04
Abstract: New process for manufacturing cephtazidime pentahydrate having formula (III), characterized in that the ester group of the compound of formula (Ia) or an acid addition salt thereof is decomposed by using exclusively aqueous hydrochloric acid, and that the cephtazidime thus obtained is crystallized in the form of pentahydrate, directly from the reaction mixture by addition of bases or in that it is first isolated by the addition of acetone and/or ethanol or another water-soluble anti-solvent of cephtazidime dihydrochloride, and in that it is converted into pentahydrate by a method known per se.
Patent JP-S63168272-A (JP)
Title: Laser repairing method
Inventor: KANIKAWA MASAYA
IPC: B23K26/21
Filed: 1987-01-06
Abstract: PURPOSE:To obtain a brazed part with the excellent quality without a pinhole with the repairing at a time by using a laser heat source to remelt locally a defective fused zone. CONSTITUTION:At the time of repairing the pinhole being generated when a moving blade 1 and stellite material 2 are brazed, the laser heat source 5 is used to control a heat affected zone 7 of the heating at the time of repairing as narrowly as possible. Then, an area of a remelting zone 6 is restricted to the narrow area of only the surface zone of the brazing where the pinhole is generated. In this way, the quantity of vapor of low melting point metal is reduced and besides, its separation from the surface is facilitated and the occurrence of the pinhole is prevented by the repairing at a time.
Patent JP-S58118390-A (JP)
Inventor: HORIUCHI KOUJI
IPC: F16L3/00
Filed: 1982-01-06
Abstract: (57)【要約】本公報は電子出願前の出願データであるた め要約のデータは記録されません。
Patent JP-S60174778-A (JP)
Title: Ｎ−ヘテロシクリル−４−ピペリジンアミン
Inventor: FURANSU EDOUARUTO YANSENSU
IPC: A61K31/445
Filed: 1985-01-07
Abstract: (57)【要約】本公報は電子出願前の出願データであるた め要約のデータは記録されません。
Patent JP-S63170065-A (JP)
Inventor: TSUN AKITAKE
IPC: G06K15/00
Filed: 1987-01-05
Abstract: (57)【要約】本公報は電子出願前の出願データであるた め要約のデータは記録されません。
Patent JP-2000199405-A (JP)
Title: Cleansing system for gas turbine
Inventor: OKIHARA KAZUTERU
IPC: F02C7/00
Filed: 1999-01-05
Abstract: PROBLEM TO BE SOLVED: To reduce costs for a gas turbine cleansing system. SOLUTION: A cleansing system 1 for a gas turbine is to feed a detergent into the gas turbine to cleanse the inside thereof. The cleansing system 1 comprises a detergent tank 2 to store the detergent, a tank support seat 3 mounted above the detergent tank 2 for supporting a stock solution tank, a stock solution receiving cup mounted above the detergent tank 2, and a coupling connecting the stock solution receiving cup to a stock solution tank opening. The cleansing system 1 further comprises a stock solution feed pipe 7 connecting the stock solution receiving cup to the detergent tank 2, an air pipe 8 connected to the detergent tank 2 to pressurize the detergent, a fresh water feed pipe 9 to feed fresh water to the detergent tank, and a detergent feed pipe 10 to feed the detergent to the turbine.
Patent JP-S57114857-A (JP)
Title: Fluid circulation type thermostat
Inventor: YANAI SHINICHI
IPC: B01L7/02
Filed: 1981-01-07
Abstract: PURPOSE:To improve the precision of thermostatic temperature with a small- sized and simple construction, by dividing a part of the circulation course of constant-temperature fluid into a bypass passage and branch passage and connecting an action means of the constant-temperature fluid in the branch passage. CONSTITUTION:Constant-temperature water flows branching to a cell tube 2a and a bypass tube 4 at large branch tube 3a passing through a circulation tube 5c, after said water is fed by a pump 6 and is made at a constant temperature by a heat exchanger 7 passing through a circulation tube 5b. Moreover, a flow passed through a constant-temperature water passage of a flow cell 1 and the cell tube 2b and a flow passed through the tube 4, are joined at a large branch tube 3b and joined flow reaches the pump 6 passing through a circulation tube 5a. By repeating such circulation, the sample in the cell 1 is maintained at a constant temperature. Hereby, the stability of the constant temperature can be improved because a flow rate of the constant-temperature water is increased compared with the case not having the bypass tube and the circulation time is shortened.
Patent JP-H11194158-A (JP)
Title: Azimuth sensor
Inventor: NAITO YUTAKA
IPC: G01C17/30
Filed: 1998-01-05
Abstract: PROBLEM TO BE SOLVED: To provide an azimuth sensor for measuring the azimuth of geomagnetic line of force precisely while reducing the size. SOLUTION: An azimuth sensor comprises first and second magnetic impedance effect elements (hereinafter, referred to M1 element) 2, 3 for detecting the X and Y axis components of the magnetic line of force due to an external field, and windings 5, 6 for applying bias magnetization to the MI elements 2, 3. The MI elements 2, 3 are arranged on a same plane 4 such that the AC current passages intersect perpendicularly. The MI elements 2, 3 are made of a soft magnetic alloy principally comprising a fine crystal phase having grain size of 50 nm or less and an amorphous phase containing one or more than one kind of element selected from Fe, Co and Ni, one or more than one kind of element selected from Ti, Zr, Hf, V, Nb, Ta, Cr, Mo and W, and B.
Patent JP-H09184974-A (JP)
Title: Image pickup device
Inventor: KOBAYASHI FUTOSHI
IPC: G02B7/34
Filed: 1996-01-08
Abstract: PROBLEM TO BE SOLVED: To provide an image pickup device capable of quickly focusing without necessitating a sensor used only for focusing on a subject. SOLUTION: An aperture blade 2 with two spectacle-like holes 2a and 2b formed on a concentric circle and plural holes whose diameters are different from each other is arranged at a diaphragm position. A 1st electrical signal is taken out of the image pickup element 6 in a state where one of two holes is closed by a light shielding blade 4, and a 2nd electrical signal is taken out of the image pickup element 6 in a state where the other hole of two holes 2a and 2b is closed. A defocusing quantity is calculated by a range finding means 9 based on a phase difference between the 1st electrical signal and the 2nd electrical signal, then, a focusing lens 1a is moved in accordance with the defocusing quantity so as to focus.  Thereafter, the aperture blade 2 is rotated so that the hole of the desired aperture value may be arranged at the luminous flux position of a photographic optical system, then, photographic exposure is performed.
Patent JP-S59125657-A (JP)
Title: Manufacture of photoelectric composite element
Inventor: TASHIRO YOSHIHARU
IPC: H01L31/10
Filed: 1983-01-06
Abstract: PURPOSE:To enhance the reproducibility of patterning and the yield by eliminating the stepwise difference between the surface of a PIN unit and the surface of an FET, thereby enabling to bond a mask for exposing to form electrodes to the surface of the element. CONSTITUTION:An N type INGaAs layer 21 is formed on a semi-insulating InP substrate 20, a P type conductive unit 22 is formed by a thermal diffusing method, a CVD-SiO2 film 23 is formed, etched and removed until partial region reaches the substrate, and isolated into the PIN unit and the FET unit. The entire region of the FET unit and the film 23 of the electrode of the PIN are removed, and the PIN unit remains as the surface protective film of a P-N junction with the non-reflection coating of a photoreceiver. Contacting electrodes 24, 25 of the PIN unit, the drain and source electrode 26 of the FET unit and a gate electrode 27 are formed.
Patent JP-H08188900-A (JP)
Title: Dipping electrolytic deburring method regarding iron
Inventor: KARIYA SUSUMU
IPC: C25F3/24
Filed: 1995-01-09
Abstract: PURPOSE: To deburr a work without especially considering the interval between it and a cathode by anodizing the iron work in an electrolyte contg. halogen compd., ethylene glycol and urea while oscillating the work. CONSTITUTION: An iron work 3 having a burr due to shearing and a cathode 4 are dipped in an electrolyte 2 contg. at least one kind of halogen compd. among KCl, NaCl, KBr, NaBr, KI, NaI, KF and NaF, ethylene glycol or glycerin and urea or EDTA. Anodization is then conducted by impressing a voltage by a DC power source 5 while oscillating the work 3. Consequently, only the sharp angular burr is removed from an ionized boundary layer, and the part is selectively anodized to effectively remove the burr.
Patent MA-39833-A (MA)
Title: Nouvelle utilisation du n,n-bis-2-mercaptoéthyl isophtalamide
Inventor: HALEY BOYD EUGENE
IPC: A61P31/00
Filed: 2015-03-31
Abstract: <!--startfragment-->la présente invention concerne le n,n-bis-2-mercaptoéthyl isophtalamide, ou un sel ou dérivé pharmaceutiquement acceptable dudit composé, destiné à être utilisé pour la régénération systémique d'ascorbate, et donc dans le traitement thérapeutique de la bronchopneumopathie chronique obstructive<!--endfragment-->
Patent MA-46230-A (MA)
Title: Mutations de protéine d'enveloppe du vih stabilisant la forme trimère
Inventor: LANGEDIJK JOHANNES PETRUS MARIA
IPC: A61K39/12
Filed: 2017-09-14
Abstract: La présente invention concerne des protéines d'enveloppe du virus de l'immunodéficience humaine (vih) présentant des mutations qui stabilisent la forme trimère de la protéine d'enveloppe. Les protéines d'enveloppe du vih présentent certaines substitutions d'acides aminés à des positions particulières dans la séquence de protéine d'enveloppe. Les protéines d'enveloppe du vih décrites dans la description présentent un pourcentage amélioré de formation de trimère et/ou un rendement amélioré en trimère telles que comparées à une protéine d'enveloppe du vih qui ne possède pas l'une ou plusieurs des substitutions d'acides aminés indiquées. La présente invention concerne également des molécules d'acide nucléique et des vecteurs codant pour les protéines d'enveloppe du vih, ainsi que des compositions contenant les protéines d'enveloppe du vih, l'acide nucléique, et les vecteurs.
Patent PH-19019-A (PH)
Title: A method for naturally drying mineral pulps
Inventor: CARDINI JEAN-LOUIS
IPC: B01D21/01
Filed: 1983-03-07
Abstract: A method of spreading a pulp for the purpose of drying it naturally, the pulp having a solid fraction which has a d80 of less than 100 microns. This method comprises the following steps: (a) adjusting the level of solids of the pulp to between 2 and 25%; (b) adding a flocculating agent to the pulp and mixing it with same, the amount of said flocculating agent being between two thirds and 98% of the optimum required for the flocculation of said pulp; and (c) spreading the mixture of pulp and flocculating agent, in the open air, in a bed the sides of which are permeable, and the bottom of which has a slope of less than 5 meters per 1000 meters, said spreading taking place 1 to 20 minutes after the adding and mixing of the flocculating agent.
Patent PH-21336-A (PH)
Title: Preparation of o<-arylalkonoic acids
Inventor: SCHLOEMER GEORGE C
IPC: C07B61/00
Filed: 1983-03-27
Abstract: Pharmaceutically useful optically active  alpha -arylalkanoic acids of the formula <CHEM> where Ar is aryl and R1 is alkyl or cycloalkyl or esters, ortho esters, or amides thereof are stereoselectively prepared by contacting a reagent of the formula Ar-MX, (Ar) 2M or ArM' where M is Cd, Cu(II), Mn(II), Mg or Zn, and M' is Cu(I) or Li, and X is halogen, with an optically active compound of the formula <CHEM>  where Z is a leaving group and Y is halogen, acyloxy or <CHEM> where R' and R'' are alkyl, aryl or with N are a heterocyclic group, to form the optically active ketone of the formula <CHEM> which is ketalized and rearranged to said acid, ester, ortho ester or amide. Alternatively, said ketone is reduced to the corresponding alkanol, which is rearranged to the  alpha -arylalkanal. The alkanal so produced is converted to said acid by conventional methods.
Patent PH-24553-A (PH)
Title: Apparatus for the manufacture of composite articles using rotating molds
Inventor: GLOVER JOHN BENJAMIN
IPC: B29C45/03
Filed: 1986-07-03
Abstract: A plastics pipe or pipe coupling is made by injection moulding the plastics pipe or coupling body 1, injection moulding at least one sealing ring 3 separately but susbstantially simultaneously, and bringing the body and sealing ring together directly after the moulding while these components are still in a hot as-moulded state, so that a direct thermal bond is formed between them. Preferably, the respective moulds are opened but the components are not stripped but are brought together for bonding while still in position on respective mould members 15, 19. This eliminates intermediate handling and ensures that the moulded components remain clean and of accurate shape and dimension as they are brought together. Moulding apparatus comprises respective injection moulding cavities for the body and sealing ring, and a reversible support for carrying the sealing ring out of its mould and into contact with the moulded body.
Patent PH-23252-A (PH)
Title: Heat sealable barrier material for improved juice packaging(evoh)
Inventor: GIBBONS CHARLES E
IPC: B65D5/00
Filed: 1987-03-05
Abstract: The present invention relates to an improved container for citrus juices and other liquids. The container utilizes a paperboard barrier laminate (34, 36, 38, 40) for the containment of essential oils and the prevention of losses of Vitamin C. Also disclosed is a process of making the laminate. The laminate makes use of a layer (40) of a heat-sealable ethylene vinyl alcohol copolymer to enhance the barrier properties of the laminate.
Patent PH-26551-A (PH)
Title: (Aryl or heteroaromatic methyl)-2,2'-bi-hi-imidazoles and their use as anti-hypertensive agents
Inventor: MATTHEWS DONALD P
IPC: C07D409/14
Filed: 1988-07-28
Abstract: This invention relates to novel (aryl or heteroaromatic methyl)-2,2 min -1H-biimidazoles; to a process for their production comprising of reacting an appropriate alpha-brominated or alpha-chlorinated, substituted or non-substituted, methylated monoaromatic ring compound with 2,2 min -bi-1H-imidazole in a solvent such as ethanol in the presence of a base such as sodium hydroxide under reflux conditions; and to pharmaceutical compositions and methods of treating hypertension with such compounds.
Patent PH-26670-A (PH)
Title: Novel pyridazinamine derivative
Inventor: STOKBROEKX RAYMOND A
IPC: C07D237/24
Filed: 1988-11-23
Abstract: Novel pyridazinamine derivatives of formula <CHEM>  wherein R<1> is hydrogen, C1-6alkyl, halo, hydroxy, mercapto, trifluoromethyl, amino, mono or di(C1-6alkyl)amino, cyano, C1-6alkyloxy, aryloxy, arylC1-6alkyloxy, C1-6alkylthio, arylthio, C1-6alkylsulfinyl, C1-6alkylsulfonyl, arylsulfinyl, aryllsulfonyl, C1-6alkyloxycarbonyl, C1-6alkylcarbonyl or aryl; R<2> and R<3> each independently are hydrogen or C1-6alkyl, or R<2> and R<3> combined may form a bivalent radical of formula -CH=CH-CH=CH-  G is a bivalent radical of formula <CHEM> X is O, S, NR<8> or a direct bond; said R<8> being hydrogen or C-6alkyl; the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof, which compounds are anti-virals; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
Patent UY-33633-A (UY)
Title: ?combinación sinérgica de abamectina y bifentrina, su proceso de preparación y uso, y método utilizando la misma"
Inventor: BORGES LUIS DONIZETE
IPC: A01N53/06
Filed: 2011-09-29
Abstract: La presente invención se refiere a una formulación agroquímica sinérgica de abamectina y bifentrina, en proporciones específicas para controlar y/o combatir plagas y enfermedades en cultivos vegetales.  Se describen además los procesos de preparación, uso y método de utilización, así como el uso de abamectina y bifentrina en la preparación de la formulación agroquímica sinérgica de la invención.
Patent UY-35671-A (UY)
Title: Bioconjugados de polipéptidos de apelina sintética
Inventor: USERA AIMEE RICHARDSON
IPC: C07K19/00
Filed: 2014-07-21
Abstract: La invención proporciona un bioconjugado que comprende un polipéptido sintético de la Fórmula Io una amida, un éster o una sal del mismo, en donde X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, X12 y X13 se definen en el presente documento y una fracción de extensión de vida media en donde el péptido y la fracción de extensión de vida media se une o fusiona covalentemente, opcionalmente a través de un enlazador. La invención también se refiere a un método para la fabricación de boioconjugados de la invención, y sus usos terapéuticos
Patent UY-37442-A (UY)
Title: Derivados de fenilamina 4-sustituidos y su uso para proteger cultivos al combatir microorganismos fitopatogénicos indeseados
Inventor: MARUTI N NAIK
IPC: A01N33/06
Filed: 2017-10-13
Abstract: La presente invención se refiere a derivados de fenilamina 4-sustituidos de la fórmula general (I), donde R1 a R9 y A tienen los significados como se define en la presente descripción. La invención se refiere además a métodos para su preparación y el uso de dichos compuestos para combatir microorganismos fitopatogénicos indeseados, y agentes a tales efectos, que comprenden dichos derivados de fenilamina, todo de acuerdo con la invención. La presente invención se refiere además a un método para combatir microorganismos fitopatogénicos indeseados mediante la aplicación de derivados de fenilamina 4- sustituidos de fórmula general (I) a tales microorganismos indeseados y/o a su hábitat, de acuerdo con la invención.
Patent UY-37714-A (UY)
Title: Uso de un compuesto de picolinamida acíclica como fungicida para el control de hongos fitopatógenos en verduras
Inventor: YAO CHENGLIN
IPC: A01P3/00
Filed: 2018-05-02
Abstract: La presente divulgación se refiere al campo de agroquímicos, que incluyen el compuesto I y su uso para controlar enfermedades fúngicas en cultivos hortícolas agrícolamente útiles.
Patent YU-18694-A (YU)
Title: Praškasta smeša za aluminotermičko zavarivanje železničkih šina kao i postupak za izradu pripalne šibice za iniciranje praškaste smeše
Inventor: TODOROVIC M
Filed: 1994-04-11
Abstract: PRASKASTA SMEŠA ZA ALUMINOTERMIČKO ZAVARIVANJE ŽELEZNIČKIH ŠINA sa povećanim sadržajem ugljenika i smanjenim sadržajem mangana data je u dva sastava. Jedna praškasta smeša ima u svom sastavu određenu granulometrijsku mešavinu 83 % oksida gvožđa i duminijuma, i to 75-77 % oksida gvožđa i 23-25 % aluminijuma, do punog sastava dodaju se čelicna sačma 11 %, feromangan 5,5 % i ferotitan 0,1 %. Ova praškasta smeša je pogodna za zavarivanje šina zatezne čvrstoće 700 N/mm. Druga praškasta smeša ima u svom sastavu određenu granulometrijsku mešavinu 76,5 % oksida gvožđa i aluminijuma, i to 75-77 % oksida gvožđa i 23-25 % aluminijuma, do punog sastava dodaju se čelična sačma 14,5 % feromangan 7,5 % ferohrom 1,0 % i ferovanadijum 0,5 %. Ova praškasta smeša je pogodna za zavarivanje šina zatezne čvrstoće 900 N/mm2. Dat je sastav pripalne šibice za iniciranje reakcije praškaste smeše kod aluminotermičkog zavarivanja u svim vremenskim uslovima. Pripalnu šibicu čini homogena smeša (kalijumperhlorata 35 %, oksida gvožđa Fe20s 5 %, magnezijum prah 20 %, aluminijum prah 25 % i celuloza 15 %) rastvorena u etilacetatu kao želatinozna viskozna masa u kojoj se sukcesivnim umakanjem i suSenjem žice više puta nanosi sloj ove smeše oko 8 mm debljine na dužinu oko 100 mm.
Patent YU-44590-A (YU)
Title: Pokretna mašina za podbijanje koloseka sa poprečno i visinski podesivim agregatima za podbijanje
Inventor: THEURER J
IPC: E01B27/17
Filed: 1990-03-06
Abstract: Pronalazak se odnosi na pokretnu mašinu za podbijanje koloseka sa porečno i visinski podesivim agregatima za podbijanje koji obuhvata pokretnu mašinu (1) za podbijanje koloseka sa na voznim postoljem oslonjenim okvirom (2) mašine i jednim, oko vertikalne osovine (19, 20), paralelno ravni koloseka, bočno zakretno uležištenim okvirom (21, 22) alata, kao i poprečno na kolosek, jedan pored druge postavljenim, i preko pogona, nezavisno jedna od druge, poprečno i vertikalno pomerljivim agregatima (15, 16) za podbijanje. Agregati imaju parove alata (39, 42) koji se preko pogona (43, 44) primiču i vibriraju, sa klinovima za podbijanje (46, 47) koji se uronjavaju u tucanik. Za medjusobno nezavisno poprečno pomeranje i uležištenje dva agregata (15, 16) za podbijanje sa njihovim pogonima (48, 49) za vertikalno pomeranje, predvidjena su dva okvira (21, 22) alata, koji imaju sopstveni pogon (17, 18), nezavisno jedan od drugog.
Patent YU-64400-A (YU)
Title: Aryl fused azapolycyclic compounds
Inventor: WADSWORTH COE JOTHAM
IPC: A61P9/00
Filed: 1999-04-08
Abstract: Compounds of formula (I) and their pharmaceutically acceptable salts, wherein R1, R2, R3 and Z are defined as in the specification, intermediates in the synthesis of such compounds, pharmaceutical compositions containing such compounds and methods of using such compounds in the treatment of neurological and psychological disorders are claimed.
Patent YU-70296-A (YU)
Inventor: PHILLIPA CAPRINO
IPC: C07K/
Filed: 1996-12-26
Abstract: Dati pronalazak se odnosi na jedinjenja formule i njihove farmaceutski prihvatljive soli gde su supstituenti definisani u Specifikaciji, koja su sekretagogni hormoni rasta i koja povećavaju nivo endogenih hormona rasta. Jedinjenja datog pronalaska se koriste za tretman i prevenciju osteoporoze, kongestivnih srčanih mana, gojaznosti; uzbravanju oporavka od preloma, slabljenju protein kataboličkog odgovora posle velikih operacija, smanjenju malaksalosti i gubitka proteina kod hroničnih bolesti, ubrzavanju zarastanja rana ili ubrzavanju oporavka pacijenata koji imaju rane od opekotina, povećanju mišićne mase, metaboličkih homeostaza ili renalnih homeostaza. Jedinjenja datog pronalaska se takodje koriste za tretman kod osteoporoze u kombinaciji sa biofosfonatnim jedinjenjima kao što su alendronat, estrogen, premarin i opcijski progesteron, nekim estrogen agonistima ili antagonistima, ili kalcitonima, i farmaceutske kompozicije koje obuhvataju ova jedinjenja. Nadalje, dati pronalazak se odnosi na farmaceutske kompozicije koje se koriste za povećanje endogene produktivnosti ili otpuštanja hormona rasta kod humanih jedinki ili životinaja i one sadrže efektivnu količinu jedinjenja datog pronalaska i sekretagoga hormona rasta odabranih ih GHRP-6, Heksarelin, GHRP-1, hormon rasta otpuštajući faktor (GRF), IGF-1, IGF-2 ili B-HT920. Dati pronalazak se takodje odnosi na intermedijere koji se koriste za dobijanje jedinjenja Formule I.
Patent YU-76793-A (YU)
Title: Postupak za sintezu 3-( b-dietilaminoetil)-4metil-7-(karbetoksimetoksi)-kumarina
Inventor: DR KRSTIC LJUBOMIR
Filed: 1993-12-13
Abstract: POSTUPAK ZA SINTEZU 3-( B-DIETILAMINOETIL)-4METIL-7-(KARBETOKSIMETOKSI)-KUMARINA - Pronalazak se odnosi na postupak za sintezu 3 - (beta- dietil-aminoetil)-4-metU-7-(karbetoksimetoksi)-kumarina Pechmannovom reakcijom izmedju rezorcinola i alfa-etil-gama-brom acetsirćetnog estra, reaguju na temperaturi ispod 10В°C 3 časa, zatim se ostave da stoje na sobnoj temperaturi još 24 časa. Nagradjeni proizvod 3- (betabrometil)-4-metil-7-hudroksikumarin, kristalna supstanca sa t.t. = 187В° C. Ova supstanca se rastvara u N,N-dimetilformamidu i reaguje sa alkoholnim rastvorom dietilamina na temperaturi od 150В° - 160В°C. Proizvod je kristalisan iz etilacetata, taloženjem rastvora hlorovodonika u etru. Dobiveni 3 - (beta-dietil-aminoetil)-4-meti u obliku hlorhidrata imao je t.t. = 276В°C. Faza ovog postupka se sastoji u tome, da se supstanca rastvara u metiletil ketonu na temperaturi od 70В°C dodaje joj se etilestar bromsirćetne kiseline i refluktuje oko 8 časova. Očvrsli ostatak kao proizvod reakcije rastvara se u etilacetatu i kristališe sa t.t. = 158В° - 160В°C.