baber/WOPTO huggingface dataset:
Patent EP-4208230-A1 (EP)
Inventor: HUBERT EMMA LOUISE
IPC: A61M15/00
Filed: 2021-09-01
Abstract: Various exemplary drug delivery devices with on-board drug destruction, drug products utilizing the same, and methods of using drug delivery devices with on-board drug destruction are provided. In general, a nasal drug delivery device configured to dispense a drug therefrom into a nose includes a destruction mechanism configured to destroy drug contained in the drug delivery device. The destruction mechanism can be configured to destroy the drug before a first actuation of the drug delivery device to deliver the drug therefrom such that the destruction mechanism destroys substantially all of the drug contained in the drug delivery device. Alternatively or in addition, the destruction mechanism can be configured to destroy the drug after a first actuation of the drug delivery device to deliver the drug therefrom such that the destruction mechanism destroys substantially all of the drug remaining in the drug delivery device.
Patent EP-4127092-A1 (EP)
Inventor: TSUNO SHINGO
IPC: G02B7/02
Filed: 2021-03-22
Abstract: The object of the present invention is to provide an adhesive composition that has a low toxicity, is curable at a low temperature, and is capable of forming a cured product having high heat resistance. The present invention relates to a dual-curable adhesive composition comprising: (a1) an oxetane compound, (a2) an alicyclic epoxy compound, (a3) an aromatic glycidyl ether-based epoxy compound, (b) a photocationic polymerization initiator, and (c) a thermal cationic polymerization initiator comprising a tetrakis(pentafluorophenyl)borate compound, wherein the amount of the component (a1) is 20 to 95 parts by mass, the amount of the component (a2) is 3 to 55 parts by mass, and the amount of the component (a3) is 3 to 45 parts by mass, each based on 100 parts by mass of the total amount of the components (a1), (a2) and (a3).
Patent EP-4126266-A1 (EP)
Inventor: HU MICHELLE
IPC: A62C99/00
Filed: 2021-03-01
Abstract: L'invention concerne une composition aqueuse, qui peut être diluée avec un diluant aqueux pour fournir une composition de précurseur de mousse. La composition de précurseur de mousse peut être aérée pour former une mousse de lutte contre l'incendie. Les compositions aqueuses de lutte contre l'incendie comprennent un mélange tensioactif contenant un tensioactif à base de siloxane conjointement avec un ou plusieurs tensioactifs non ioniques, un tensioactif anionique et un tensioactif zwitterionique. Les compositions aqueuses de lutte contre l'incendie comprennent également un épaississant polysaccharidique et un solvant organique, tel qu'un alkylène glycol, du glycérol et/ou un éther glycolique.
Patent EP-4199769-A1 (EP)
Inventor: POYNTON SIMON
IPC: A24F40/51
Filed: 2021-09-10
Abstract: An aerosol provision system (1) comprising a first part (4) comprising a reservoir (44) for storing an aerosolisable material, and a sensor (70) for detecting a level of the aerosolisable material in the reservoir (44). The sensor is configured to output sensor information relating to the level of the aerosolisable material in the reservoir (44). The aerosol provision system (1) further comprises a vaporiser (48) for vaporising the aerosolisable material; and a second consumable part (8), for holding flavouring material (84), located downstream of the vaporiser (48). The aerosol provision system (1) is configured to process the sensor information to determine an amount of the aerosolisable material in the reservoir (44), and generate a signal to replace the second consumable part (8) when the amount of the aerosolisable material is determined as reaching, or falling below, a predetermined amount.
Patent EP-4127208-A1 (EP)
Inventor: QI XIAOYANG
IPC: C12Q1/37
Filed: 2021-04-02
Abstract: A method of non-invasively diagnosing and treating a cancer characterized by high surface phosphatidylserine (PS) expression in a subject in need thereof is provided, the method including: obtaining a liquid biological sample from the subject; detecting a presence of cancer-secreted soluble phosphorylated Heat shock protein-70 (Hsp70) in the liquid biological sample; diagnosing the subject with a cancer characterized by high surface PS expression when cancer-secreted soluble phosphorylated Hsp70 is present in the liquid biological sample; and administering an anti-cancer therapy targeted to high surface PS expressing-cancers to the diagnosed subject. Also provided is a method for monitoring therapeutic efficacy of a treatment in a subject with a cancer characterized by high surface PS expression.
Patent EP-4143833-A1 (EP)
Inventor: SHCHERBAKOV DENIS
IPC: G16C60/00
Filed: 2021-09-30
Abstract: The fragrance ingredient or composition spatial recognisability prediction method (200) to prepare a fragrance composition comprising said fragrance ingredient or composition, comprises the steps of: - selecting (205), upon a computer interface, a value representative of between one and two of the following parameters: - a minimum sensory intensity level, corresponding to a predetermined minimum psychophysical intensity for the ingredient, - a maximum distance, corresponding to a distance at which the ingredient is to be perceived at a minimum predetermined psychophysical intensity level or - a quantity of the ingredient in liquid phase, wherein the selected value is selected within a range of at least two distinct values, - computing (215), by a computing system, a value representative of either one of the following parameters: - a minimum sensory intensity level, corresponding to a predetermined minimum psychophysical intensity for the ingredient, - a maximum distance, corresponding to a distance at which the ingredient is to be perceived at a minimum sensory intensity level selected or set by default, or - a quantity of the ingredient in liquid phase and wherein the computed value is representative of a parameter other than the parameter associated with the selected value and wherein a value for the parameter neither selected nor computed is set to a default value, said ingredient digital identifier corresponding to a physical ingredient to be used within a fragrance composition to be prepared as a function of the computed and selected values.
Patent EP-4217511-A1 (EP)
Inventor: DOWSETT MITCHELL
IPC: C12Q1/6886
Filed: 2021-09-24
Abstract: The present invention provides a method for predicting whether a human subject having breast cancer will be resistant to, or sensitive to, therapy with a eye1in-dependent kinase (CDK) inhibitor, the method comprising: a) measuring the gene expression in a sample obtained from the breast tumour of the patient to obtain a sample gene expression profile of at least the following modules: (i) a luminal vs. non-luminal module comprising at least four genes selected from the group consisting of: ACTR3B, ANLN, BAG1, BCL2, BIRC5, BLVRA, CCNB1, CCNE1, CDC20, CDC6, CDCA1, CDH3, CENPF, CEP55, CXXC5, EGFR, ERBB2, ESR1, EX01, FGFR4, F0XA1, F0XC1, GPR160, GRB7, KIF2C, KRT14, KNTC2, KRT17, KRT5, MAPT, MDM2, MELK, MIA, MKI67, MLPH, MMP11, MYBL2, MYC, NAT1, 0RC6L, PGR, PHGDH, PTTG1, RRM2, SFRP1, SLC39A6, TMEM45B, TYMS, UBE2C and UBE2T; (ii) a E2F module comprising at least five genes selected from the group consisting of: ARHGAP11A, ATAD2, C10ORF119, CASP8AP2, CLSPN, DCK, DNAJC9, FANGD2, FBX05, FKBP5, H2AFZ, KIAA0101, KPNB1, NUP62, RANBP1, RET, SFRS1, SFRS10, SFRS7, SNRPD1, STMN1 and TMPO; (ill) an RBI module comprising the gene RB1; and (iv) a CCNE1 module comprising the gene CCNE1; and b) making a prediction of whether the subject will be resistant to or sensitive to said CDK inhibitor treatment based on the sample gene expression profile comprising said modules (i) to (iv). Also provided are related methods of treatment, computer-implemented methods of predicting treatment response and systems for use in such methods.
Patent EP-4222481-A1 (EP)
Inventor: LONGYEAR JENNIFER ELISE
IPC: G01N21/88
Filed: 2021-09-29
Abstract: System and method for estimating aquatic environment-originating biofilm biomass on a coating of an object. The method includes obtaining one or more digital images of a fouled portion of the coating on the object and determining from each of the one or more images a respective reflectance value for the portion of the coating. The method includes determining on the basis of the one or more reflectance values a value of a spectral index representative of biomass and calculating a biomass pigment surface area density on the basis of the spectral index, SI, and one or more calibration values determined for a reference coating. The method includes compensating the calculated biomass pigment surface area density for the reflectance of the coating of the object by applying a compensation associated with the difference of the reflectance of the coating of the object relative to the reference coating.
Patent EP-4136503-A1 (EP)
Title: Multi-region electro-optic element
Inventor: SAENGER NAYVER MARIO F
IPC: G02F1/153
Filed: 2021-04-16
Abstract: An electro-optic element having multiple regions is disclosed. The electro-optic element comprises an electro-optic medium disposed between two electrodes. Further, the electro-optic medium is operable between activated and un-activated states based, at least in part, on exposure to an electrical potential. In some embodiments, in response to an electrical potential of a first polarity, the electro-optic medium may be substantially activated in one region and substantially un-activated in another region. In response to an electrical potential of a second polarity opposite the first polarity, the electro-optic medium may be substantially activated in both regions. In other embodiments, the electro-optic medium is operably activated such that electro-optic medium is activated in one region and un-activated in another region, regardless of polarity.
Patent EP-4213830-A1 (EP)
Inventor: ELINAV ERAN
IPC: A61K31/195
Filed: 2021-09-20
Abstract: L'invention concerne une méthode de traitement de l'obésité chez un sujet en ayant besoin. La méthode comprend l'administration au sujet d'une quantité thérapeutiquement efficace d'un agent qui augmente spécifiquement la quantité d'hexadécadiénoate (16:2n6), de N-acétylglycine, de l-palmitoyl-2-gamma-linolénoyl-GPC (16:0/18:3n6) et/ou d'Hexanoylglycine ; ou d'un agent qui diminue la quantité de diméthylglycine (DMG) dans le métabolome fécal du sujet. L'invention concerne également des agents appropriés pour celle-ci.
Patent EP-4103448-A1 (EP)
Title: Transport- und verladeanordnung für ein kraftfahrzeug
Inventor: MARTIN KNUT
IPC: B62B5/00
Filed: 2021-10-28
Abstract: Eine Transport- und Verladeanordnung (2) für ein Kraftfahrzeug (4), wie insbesondere einen PKW mit einem sich bis zu einer Hecköffnung (6) erstreckenden Laderaum (8), weist einen Transportwagen (10), der ein Fahrgestell (14) mit mehreren Abrollmitteln (16) und wenigstens eine Transportaufnahme (12) aufweist, wobei das Fahrgestell (14) zwischen einer Transportstellung und einer Verladestellung verstellbar ist, und eine im Laderaum (8) anbringbare Verladevorrichtung (20) auf, die einen Verlademechanismus (24) zum Ein- und/oder Ausladen des Transportwagens (10) in beziehungsweise aus dem Laderaum (8) aufweist, wobei der der Transportwagen (10) eine elektrische betriebene Höhenverstellungseinrichtung (34) aufweist, mittels der in der Transportstellung eine Höhe (H, H1, H2) des Transportwagens (10) einstellbar ist. Dabei ist vorgesehen, dass das Fahrgestell (14) zur Einstellung der Höhe (H, H1, H2) des Transportwagens (12) ein wenigstens teilweise teleskopierbares Gestänge (36) aufweist und drei Abrollmittel (16) an jeweils einer Teleskopeinrichtung (37) gehalten sind, wobei die Teleskopeinrichtungen (37) voneinander unabhängig verstellbar sind.
Patent EP-4150766-A1 (EP)
Title: Exploiting locality of prime data for efficient retrieval of data that has been losslessly reduced using a prime data sieve
Inventor: SHARANGPANI HARSHVARDHAN
IPC: H03M7/30
Filed: 2021-05-10
Abstract: An amount of memory needed to hold prime data elements during reconstitution may be determined by examining the creation and usage of prime data elements and their spatial and temporal characteristics during data distillation.
Patent EP-4149504-A1 (EP)
Inventor: CHOUINARD FRANÇOIS
IPC: A61K36/185
Filed: 2021-05-17
Abstract: Traditional methods of hash production are very labor intensive, and the skills of the individual play a key role in defining the quality of the finished product. Hash production requires multiple steps and lacks automation, and thus, it is not easily scaled and very costly for commercial production. The present disclosure relates to hashish product comprising a cohesive mass of isolated cannabis trichomes and having substantially uniform characteristics and to a process of making same. The process comprises providing isolated cannabis trichomes; mixing the isolated cannabis trichomes under conditions sufficient to obtain a substantially homogeneous resinous mixture; and retrieving at least a portion of the mixture through an extrusion die to obtain the hash product.
Patent EP-4237261-A1 (EP)
Inventor: CAREME CHRISTOPHER
IPC: B60C11/00
Filed: 2021-10-22
Abstract: The present invention relates to a tyre, of which the performance in terms of longitudinal grip on dry ground is improved. The tread is provided with at least one tread pattern block (511) having a contact face (9) intended to come into contact with the roadway while the tyre is running. The tread pattern block (511) comprises at least two axial portions. A first axial portion (51) is made up of a base material, and a second axial portion (52) is made up of a stiffer material. The ratio of the shear dynamic stiffness modulus of the material of the second portion (52) divided by that of the material of the first portion (51) is in the range [5;30]. The tread also comprises a circumferential groove (6) bordered by a channel (7), the width of which is between [3 x L52, 1.01xL52], where L52 is the axial width of the contact face of the second axial portion (52).
Patent EP-4244962-A1 (EP)
Title: Bistable electromagnetic actuator and aircraft brake valve provided with such an actuator
Inventor: MONSAINT LAURENT
IPC: H02K26/00
Filed: 2021-11-10
Abstract: The invention relates to a bistable electromagnetic actuator (in direction A' or B') comprising a casing (11') extending partially around an axis of rotation (X) of the actuator, an excitation coil (12') supported by the casing (11') capable of generating a magnetic flux, a rotor (21') movable about the axis of rotation of the actuator and capable of being immobilised in two stable angular positions (in direction A' or B') depending on the magnetic flux generated by the coil (21'), an actuating member coupled to the rotor (21') in order to form a rotatable assembly; and a manual control device comprising a drive shaft or kinematically coupled to the rotor (21') so that a rotation of said drive shaft causes the rotor to rotate.
Patent EP-4232995-A1 (EP)
Title: System and method for acquiring and displaying an image of a subject
Inventor: VINCELETTE REBECCA L
IPC: G06T3/40
Filed: 2021-10-25
Abstract: A method and system is disclosed for displaying acquired image data of a subject. The image may include a high resolution of clear image based on the acquired image data. The image may assist in evaluating the subject.
Patent EP-4247618-A1 (EP)
Inventor: LI YAN SHENG
IPC: B29C64/00
Filed: 2021-11-16
Abstract: The present disclosure relates to a pulverulent composition comprising (a) at least one phosphate flame retardant synergist selected from hydrogen phosphate salt, dihydrogen phosphate salt, hydrate thereof and mixture thereof; (b) at least one flame retardant; and (c) at least one thermoplastic polymer. The present disclosure also relates to a 3D-printed object formed from the pulverulent composition and a process of forming 3D-printed object. The pulverulent composition shows good printability and the 3D-printed objects obtained from the thermoplastic powders not only have excellent flame-retardant performance but also have good mechanical properties.
Patent EP-4244235-A1 (EP)
Inventor: GOWANS ELLEN
IPC: C07K7/08
Filed: 2021-11-12
Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which bind to TfR1. The invention also relates to multimeric binding complexes which comprise at least two of said bicyclic peptide ligands. The invention also includes pharmaceutical compositions comprising said peptide ligands and multimeric binding complexes and the use of said peptide ligands, and multimeric binding complexes and pharmaceutical compositions in preventing, suppressing or treating a disease or disorder through TfR1 mediated delivery of a therapeutic agent.
Patent EP-4256443-A1 (EP)
Title: Document body vectorization and noise-contrastive training
Inventor: AHMED JUNAID
IPC: G06F16/332
Filed: 2021-11-15
Abstract: Document embedding vectors for each document of a corpus may be generated by combining embedding vectors for document subparts, thereby yielding a final embedding vector for the document. A machine learning model is trained using a query corpus and the document corpus, where the model generates a ranking score for a given (query, document) pair. During training, rankings scores are generated using the model, such that the training dataset is further refined using the generated ranking scores. For example, top documents and a negative document may be determined for a given query and subsequently used as training data. Multiple negative documents may therefore be determined for a given query. A negative document for a given query may be determined from the negative documents using noise-contrastive estimation. Such determined negative documents may be evaluated using a loss function during model training, thereby yielding a more robust model for search processing.
Patent EP-4163303-A1 (EP)
Inventor: MARTÍNEZ RODRIGO ABEL
IPC: C07K19/00
Filed: 2021-05-26
Abstract: Synthetic chimera which includes four multi-epitope peptides against Leishmania. Each of the peptides has been selected from a Leishmania infantum protein. These are nucleosomal histones H2A, H2B, H3 and H4. The invention also relates to a pharmaceutical composition which includes the synthetic chimera. It also concerns a prophylactic and/or therapeutic vaccine against Leishmania spp. for use in mammals and especially in humans and dogs.
Patent EP-4171140-A1 (EP)
Inventor: GUAN PENG
IPC: H04W72/04
Filed: 2021-06-24
Abstract: This application discloses a beam indication method and a communications apparatus. The method includes: A terminal device receives configuration information sent by an access network device, where the configuration information is used to indicate the terminal device to transmit a plurality of physical channels and/or physical signals based on a unified beam. The terminal device receives downlink control information DCI signaling sent by the access network device. The terminal device determines, based on the configuration information and a beam indicated by the DCI signaling, a beam used by the terminal device to transmit a first physical channel or signal, where the beam used by the terminal device to transmit the first physical channel or signal is the unified beam. Based on the beam indication method, provided that the access network device notifies, to the terminal device, the beam used to transmit the first physical channel or signal, the terminal device can determine, based on the beam used to transmit the first physical channel or signal, a beam used to transmit another physical channel and/or physical signal. It can be learned it is helpful to reduce beam indication signaling overheads.
Patent EP-4172101-A1 (EP)
Inventor: MALAEB WADDAH ARKAN
IPC: B81B1/00
Filed: 2021-06-25
Abstract: The present disclosure is directed in one non-limiting embodiment to a biochip for growing ductal tissue including at least one membrane structure, wherein the membrane structure includes at least one porous membrane configured to provide a mimetic cellular environment, at least one chassis, wherein the at least one chassis includes a channel configured to support the at least one membrane structure and at least one microfluidic channel in fluid communication with the channel supporting the at least one membrane structure and at least one cover slip, wherein the pat least one chassis is configured such that an internal space is provided within the at least one chassis and capable of creating at least one channel within the at least one chassis, wherein the internal space created between the chassis provides a compartment that is internal relative to the body of the chassis but external relative to the membrane structure.
Patent EP-4171026-A1 (EP)
Title: Immersive media data processing method and device, and storage medium and electronic device
Inventor: LI QIUTING
IPC: H04N13/106
Filed: 2021-06-07
Abstract: Provided are a method and apparatus for processing immersive media data, a storage medium, and an electronic apparatus. The method comprises: acquiring immersive media data corresponding to a current viewing posture of a user, wherein a three-dimensional viewing space is used to limit viewing content of the user; and rendering the immersive media data corresponding to the current viewing posture, wherein when the current viewing posture is within the three-dimensional viewing space, the acquired immersive media data is rendered; or when the current viewing posture has moved or is moving outside the three-dimensional viewing space, the immersive media data is rendered according to handling information of the three-dimensional viewing space, The present invention solves the problem of the rendering and presentation of visual content viewed by a user being affected, thereby achieving quick, efficient and high-quality reconstruction and rendering of visual content during viewing, so as to satisfy the optimal immersive experience effect.
Patent EP-3981830-A1 (EP)
Title: Resin composition and molded article
Inventor: SASAKAWA Gouki
IPC: C08L67/02
Filed: 2021-09-21
Abstract: An object of the present invention is to provide a composition containing a biologically degradable resin from which a molded article having suppressed deterioration of the tensile strength and the elongation at the breaking point thereof can be obtained. The present invention provides a resin composition including a biologically degradable resin, a heavy calcium carbonate, and acetyl tributyl citrate, in which a mass ratio of the biologically degradable rein to the heavy calcium carbonate is 10:90 to 70:30, the biologically degradable resin includes at least polybutylene adipate terephthalate or polybutylene succinate adipate, a content of the polybutylene adipate terephthalate or the polybutylene succinate adipate relative to the biologically degradable resin is 70% or more by mass, and a content of the acetyl tributyl citrate relative to the resin composition is 5.0% or more and 20.0% or less by mass.
Patent EP-4166326-A1 (EP)
Inventor: ISHII RIKA
IPC: B65D65/40
Filed: 2021-06-11
Abstract: Provided is a gas barrier laminate including: a paper substrate; an anchor coat layer including a first polyolefin having a polar group; a vapor-deposited layer; and an overcoat layer including a second polyolefin having a polar group, in order, in which the gas barrier laminate includes a layer including a polyvinyl alcohol-based resin between the paper substrate and the anchor coat layer or between the anchor coat layer and the vapor-deposited layer.