baber/WOPTO huggingface dataset:
Patent AU-2017250769-A1 (AU)
Title: Transgenic T cell and chimeric antigen receptor T cell compositions and related methods
Inventor: SADELAIN MICHEL W J
IPC: C07K14/725
Filed: 2017-04-14
Abstract: The invention provides a T cell wherein one or more therapeutic transgenes is integrated at a within the genome of the cell such that expression of the transgene is under control of an endogenous promoter of the T cell. The invention additional provides methods of making and using such cells to treat a subject with T cell therapy. The invention also provides a T cell wherein a recombinant nucleic acid sequence encoding a chimeric antigen receptor (CAR) is integrated at a first site within the genome of the cell such that the CAR is expressed by the cell at the surface of the cell, and wherein integration of the nucleic acid encoding the CAR at the first site reduces or prevents expression of a functional T cell receptor (TCR) complex at the surface of the cell. The invention additional provides methods of making and using such cells to treat a subject with CAR therapy.
Patent AU-2017256692-A1 (AU)
Title: Wound dressings and methods of use with integrated negative pressure source having a fluid ingress inhibition component
Inventor: ASKEM BEN ALAN
IPC: A61F13/00
Filed: 2017-04-26
Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment. In some embodiments, a negative pressure source is incorporated into a wound dressing apparatus so that the wound dressing and the negative pressure source are part of an integral or integrated wound dressing structure that applies the wound dressing and the negative pressure source simultaneously to a patient's wound. The negative pressure source and/or electronic components may be positioned between a wound contact layer and a cover layer of the wound dressing. A component may be used to prevent wound exudate from contacting the inlet of the negative pressure source.
Patent AU-2017272319-A1 (AU)
Title: Trans-jugular carotid artery access methods
Inventor: PILLAI LAKSHMIKUMAR
IPC: A61M1/10
Filed: 2017-12-08
Abstract: TRANS-JUGULAR CAROTID ARTERY ACCESS METHODS Methods and devices for trans-jugular carotid access are disclosed. Methods within the scope of this disclosure include methods of trans-jugular carotid access originating in the leg of a patient or other location remote to the jugular vein and carotid artery and methods originating at the neck of a patient. Devices used in connection with the disclosed methods may comprise access catheters (42', 70), lumens (46, 50), and stylets (58).
Patent AU-2017276685-A1 (AU)
Title: Antagonist antibodies that t bind to human TGFB1, TGFB2 and to TGFB3 and their use for the treatment of lung fibrosis
Inventor: BON HELENE
IPC: A61P11/00
Filed: 2017-06-07
Abstract: The present disclosure relates to TGF-beta antibodies and binding fragments thereof, DNA encoding the same, host cells comprising said DNA and methods of expressing the antibody or binding fragment in a host cell. The disclosure also extends to pharmaceutical compositions comprising the antibody or a binding fragment thereof and use of the antibody, binding fragment and compositions comprising the same in treatment of various diseases including fibrosis.
Patent AU-2017281706-A1 (AU)
Title: Control of polymer network structures via nanogels
Inventor: STANSBURY JEFFREY W
IPC: C08F14/00
Filed: 2017-06-23
Abstract: A method of increasing a polymerization reaction rate of a base monomer composition that has slow free-radical polymerization kinetics. The method comprises combining an effective amount of a nanogel to the base monomer composition to form a monomer-nanogel mixture having a polymerization reaction rate that is greater than the polymerization reaction rate of the base monomer composition when subjected to an identical free-radical polymerization reaction conducted under identical conditions. The base monomer composition comprises one or more slow-kinetic monomers with slow free radical polymerization kinetics in which <25% of the double bonds are converted within the first 10 mintes of said reaction. The nanogel is soluble in the base monomer composition. The nanogel is derived from a nanogel-forming monomer mixture that comprises: at least one monovinyl monomer; at least one divinyl monomer; a chain transfer agent; and an initiator.
Patent AU-2017290061-A1 (AU)
Title: Interactive transport services provided by unmanned aerial vehicles
Inventor: LESSER JONATHAN
IPC: G06Q50/28
Filed: 2017-06-28
Abstract: Embodiments relate to a client-facing application for interacting with a transport service that transports items via unmanned aerial vehicles (UAVs). An example graphic interface may allow a user to order items to specific delivery areas associated with their larger delivery location, and may dynamically provide status updates and other functionality during the process of fulfilling a UAV transport request.
Patent AU-2017295552-A1 (AU)
Title: Single-stage centrifugal pumping unit
Inventor: KUSHNAREV VLADIMIR IVANOVICH
IPC: F04D29/22
Filed: 2017-07-07
Abstract: A single-stage centrifugal pumping unit comprises a double entry pump with a housing, which consists of a base and a cover, manifolds, a rotor, and a volute. The volute is configured in the form of a separate, independent component. Parts of the outside surface thereof, which are intended to be accommodated in cradles provided for this purpose in the cover and the housing, correspond to the shape of the surfaces of said cradles. An impeller and the volute are replaceable as a pair. The parameters of the impeller and the volute in each pair are calculated to provide maximum efficiency while ensuring the requisite feed and pressure. The invention is directed toward providing a pumping unit which demonstrates peak efficiency in non-nominal modes while having a simplified design and being universal in nature.
Patent AU-2017306557-A1 (AU)
Title: Gene editing of CAR-T cells for the treatment of T cell malignancies with chimeric antigen receptors
Inventor: DIPERSIO JOHN F
IPC: C07K14/705
Filed: 2017-08-03
Abstract: The present disclosure provides the use of fratricide-resistant chimeric antigen receptor T (CAR-T) cells targeting antigens expressed by T cell malignancies.
Patent AU-2017326439-A1 (AU)
Title: Integrated control system for a well drilling platform
Inventor: PARTHASARATHY ANAND
IPC: E21B21/08
Filed: 2017-09-15
Abstract: An integrated control system (ICS) for a well drilling platform is provided, which well drilling platform has a plurality of control systems and devices. The ICS includes an ICS controller is in communication with a master control. The ICS controller includes a memory device coupled to a processor. Instructions executed by the processor cause the ICS controller to: communicate with each of the control systems to determine a status of each of the control systems; cause the master control display to display status information for at least one of the control systems; in response to an operator input perform a well drilling platform function, the function requiring a coordinated state between a first control system and at least a second control system, configure the first control system and the second control system into a coordinated state.
Patent AU-2017351069-A1 (AU)
Title: Oral care compositions and methods of use
Inventor: ONG JANE
IPC: A61K8/49
Filed: 2017-10-24
Abstract: Disclosed herein are oral care compositions comprising naringin:Zinc complexes having a 2:1 naringin to zinc molar ratio. Methods of making and using the compositions are also provided.
Patent AU-2017357488-A1 (AU)
Title: Substituted quinoxaline derivatives as inhibitors of PFKFB
Inventor: BUCHSTALLER HANS-PETER
IPC: A61K31/501
Filed: 2017-11-06
Abstract: The present invention relates to substituted quinoxaline derivatives. These compounds areusefulfor the prevention and/or treatment of medical conditions hyperproliferative diseases.
Patent AU-2017420370-A1 (AU)
Title: Adhesive pattern residing on a moving base web
Inventor: NIEDT JAMES
IPC: D04H1/593
Filed: 2017-06-23
Abstract: A unique and distinctive adhesive pattern is applied to a base web, such as a nonwoven web. The adhesive pattern can include a plurality of treated discrete areas that can extend parallel in the longitudinal direction of the web. Each treated discrete area can include a head portion connected to a tail portion. The head portion, in one embodiment, can have a greater amount of adhesive composition based on mass per area in relation to the amount of adhesive composition contained in the tail portion. The overall length of the treated discrete area can be relatively short in relation to adhesive patterns produced in the past using conventional slot coating processes. The adhesive pattern provides a secure attachment to an adjoining material and can provide various processing advantages.
Patent WO-2018136992-A1 (WO)
Title: Système de préconditionnement ischémique à distance spécifique d'un patient, doté d'une unité de commande de rétroaction multicouche
Inventor: JAVADZADEGAN ASHKAN
IPC: A61B5/026
Filed: 2018-01-25
Abstract: L'invention concerne un système de préconditionnement ischémique à distance ayant un manchon conçu pour se contracter autour d'un membre d'un sujet ; un actionneur relié au manchon qui, lorsqu'il est actionné, amène le manchon à se contracter autour du membre du sujet ; un dispositif de commande qui commande l'actionneur afin qu'il fonctionne selon un protocole de traitement qui comprend une pluralité de cycles de traitement de contraction et de relâchement du manchon autour du membre du sujet ; un premier capteur servant à mesurer le niveau de saturation en oxygène dans le sang du membre ; un second capteur servant à mesurer une propriété de pouls dans le membre ; et une unité de commande de rétroaction en communication avec le dispositif de commande et conçue pour recevoir la mesure de saturation en oxygène provenant du premier capteur et la propriété de pouls provenant du second capteur ; l'unité de commande de rétroaction étant en outre conçue pour : comparer le niveau de saturation en oxygène à une première valeur prédéterminée et signaler au dispositif de commande de faire fonctionner l'actionneur pour gonfler davantage le manchon si le niveau de saturation en oxygène est supérieur à la valeur prédéterminée ; et comparer la propriété de pouls à une seconde valeur prédéterminée et signaler au dispositif de commande de faire fonctionner l'actionneur pour gonfler davantage le manchon si la fréquence cardiaque ou l'intensité du pouls est supérieure à la valeur prédéterminée.
Patent WO-2018213882-A1 (WO)
Inventor: ILAG LEODEVICO L
IPC: A61P29/00
Filed: 2018-05-23
Abstract: La présente invention concerne des extraits provenant d'Arthrospira physiologiquement stressé ayant une activité anti-inflammatoire et/ou la capacité de stimuler la croissance de nouvelles cellules, des compositions comprenant les extraits ayant une activité anti-inflammatoire et/ou la capacité de stimuler la croissance de nouvelles cellules, et l'utilisation de telles compositions dans le traitement de maladies ou de troubles ayant une base inflammatoire et/ou dans le traitement de maladies ou de troubles cutanés, les maladies ou les troubles cutanés n'étant pas le résultat d'une infection ou d'une infestation microbienne.
Patent WO-2019051544-A1 (WO)
Title: Integrated intelligent irrigation system design, implementation and monitoring
Inventor: PRYOR JAMES MATTHEW
IPC: G05B19/46
Filed: 2018-09-12
Abstract: A method for optimally designing an irrigation system and managing/ operating the designed irrigation system in real time comprising: • receiving data associated with a proposed irrigation design; • analysing the proposed design comprising one or more proposed measurements and automation requirements; • retrieving one or more pre-established estimation rules from a data store and mapping them with the proposed design; • estimating additional measurement and automation requirements based on one or more such estimation rules; • adjusting one or more estimation rules based on real data associated with operation of a previous/current irrigation system; • estimating one or more of acquisition, installation and operating costs based on one or more of: hardware costs; radio network propagation characteristics (optionally of terrain, crop, etc); other factors that have historically contributed to ownership cost; • displaying to a user one or more of such estimated costs; • calculating one or more alternative designs and displaying the associated information.
Patent AU-2018201301-A1 (AU)
Title: Prevention of disulfide bond reduction during recombinant production of polypeptides
Inventor: KAO YUNG-HSIANG
IPC: C07K14/00
Filed: 2018-02-22
Abstract: The invention concerns methods and means for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide 5 containing polypeptides, including antibodies, from recombinant host cell cultures. 10001428_1 (GHMatters) P82944.AU.3
Patent AU-2018202810-A1 (AU)
Title: Computer internal architecture
Inventor: DEGNER BRETT W
IPC: G06F1/16
Filed: 2018-04-23
Abstract: An internal component and external interface arrangement for a cylindrical 5 compact computing system is described that includes at least a structural heat sink having triangular shape disposed within a cylindrical volume defined by a cylindrical housing. A computing engine having a generally triangular shape is described having internal components that include a graphics processing unit (GPU) board, a central processing unit (CPU) board, an input/output (I/O) interface board, an interconnect 10 board, and a power supply unit (PSU).
Patent AU-2018203066-A1 (AU)
Title: Computer implemented method and apparatus for establishing and executing a dynamic equity instrument
Inventor: STRNAD II JAMES FRANK
IPC: G06Q40/00
Filed: 2018-05-02
Abstract: Computer Implemented Method And Apparatus For Establishing And Executing A Dynamic Equity Instrument Equity returns, expenses, and risk in a real estate asset are shared dynamically between an investor and an owner of rights. In one of several computing system based embodiments, holding the real estate asset is considered to be a joint venture, 10 contributions by the owner and the investor to the joint venture are calculated periodically, and residual accounts or payments are adjusted to balance out the venture. Some of the residual accounts may exist outside of the conventional capital structure consisting of various debt and equity interests associated with the asset. 1 r~t o-J or (1) C i W t cr E E Ln E I-o wI Eco -W >-
Patent AU-2018204918-A1 (AU)
Title: Test tape cassette and analytical test tape therefor
Inventor: DREIBHOLZ JOERG
IPC: G01N33/487
Filed: 2018-07-05
Abstract: TEST TAPE CASSETTE AND ANALYTICAL TEST TAPE THEREFOR An analytical test tape for use in a test tape cassette (14) having a carrier tape that can be wound onto a spool and a plurality of test elements (24) that are distributed on the carrier tape in the tape longitudinal direction and have a spreading fabric (30) for applying body fluid and an underlying reagent layer (36) for detecting an analyte in the body fluid, wherein the spreading fabric (30) is formed from fabric threads (44, 46) that are crossed in a grid shape, wherein the bending stiffness of the spreading fabric (30) is sectionally modified.
Patent AU-2018206111-A1 (AU)
Title: Substituted fused heteroaryl compound serving as a kinase inhibitor, and applications thereof
Inventor: CAI SUIXIONG
IPC: A61K31/4985
Filed: 2018-01-09
Abstract: The present invention provides a substituted fused heteroaryl compound serving as a kinase inhibitor, and applications thereof. Specifically, the present invention provides a compound represented by formula I, or a medicinal salt or a prodrug thereof, A
Patent AU-2018211893-A1 (AU)
Title: Fitting element for use in rehabilitation of pipelines and method for producing the same
Inventor: BERGMAN ANANDE
IPC: B29C65/00
Filed: 2018-01-24
Abstract: Fitting element (1) for use in rehabilitation of pipelines with a liner (2), the fitting element comprising a composite article of reinforcing fibers and a resin composition, wherein a first part (11) of the fitting element comprises reinforcing fibers and a substantially fully cured resin composition, wherein a second part (12) of the fitting element comprises dry reinforcing fibers that can accept a curable resin composition that optionally originates from the liner (2) to form a functional joint between the fitting element (1) and at least a part of the liner (2), and wherein an interface layer (15) of the fitting element structurally connects the first (11) and the second part (12) by comprising reinforcing fibres of the second part (12) and resin from the first part (11).
Patent AU-2018215537-A1 (AU)
Title: Metabolic engineering for microbial production of terpenoid products
Inventor: KUMARAN AJIKUMAR PARAYIL
IPC: C12N1/00
Filed: 2018-02-05
Abstract: In various aspects and embodiments, the invention relates to bacterial strains and methods for making terpene and terpenoid products. The invention provides bacterial strains with improved carbon flux through the MEP pathway, to thereby increase terpene and/or terpenoid product yield by fermentation with carbon sources such as glucose.
Patent AU-2018227888-A1 (AU)
Title: Method for producing lithium hydroxide from lithium-containing ore by means of chlorination and chloroalkali process
Inventor: BIGLARI MOSTAFA
IPC: C25B1/02
Filed: 2018-02-02
Abstract: The invention relates to a method for producing lithium hydroxide (4), in particular high-purity lithium hydroxide, for use in batteries and/or accumulators, from lithium-containing ore and/or mineral, and/or lithium-containing earths (1) by means of a chloroalkali process, wherein a solution is to be provided for increasing the extraction rate of high-purity lithium hydroxide when using a chloroalkali process. This aim is achieved in that in a chlorination step (A) a lithium chloride solution (2) is produced, wherein initially, the lithium-containing ores and/or minerals and/or earths (1) are chlorinated using chlorine gas (5), and subsequently, are leached out, in particular with the use of water. In a subsequent purification step (B), a high-purity lithium chloride solution (3) is generated, wherein the lithium chloride solution (2) is purified, in particular by removing cations, such as sodium, potassium, calcium, magnesium, and/or iron, from the lithium chloride solution (2). In a subsequent electrolysis step (C), lithium hydroxide (4), in particular high-purity lithium hydroxide, is then produced, wherein the high-purity lithium chloride solution (3) is subjected to a membrane electrolysis generating chlorine gas (5) and hydrogen as by-products.
Patent AU-2018247249-A1 (AU)
Title: Therapeutic compositions for treating pancreatic cancer
Inventor: LIU SHENG-YUNG
IPC: C07C49/543
Filed: 2018-10-10
Abstract: The present invention is directed to therapeutic compositions for treating pancreatic cancer comprising a cyclohexnone compound and one or more anti-cancer agents.
Patent AU-2018259016-A1 (AU)
Title: Microparticles and method for modifying the permeability
Inventor: O'REILLY RACHEL KELLY
IPC: C09K8/516
Filed: 2018-04-24
Abstract: A process for reducing the permeability to water of a thief zone of a porous and permeable subterranean petroleum reservoir by injecting a dispersion of polymeric microparticles in an aqueous fluid down a well and into the thief zone, wherein the polymeric microparticles comprise crosslinked copolymer chains having structural units derived from (i) a water-soluble or water- dispersible monomer with a betaine group, (ii) a water-insoluble monomer, and, (iii) a cross- linking monomer having at least two sites of ethylenic unsaturation, and the polymeric microparticles have a transition temperature above the maximum temperature encountered in the well and at or below the maximum temperature encountered in the thief zone and, and the polymeric microparticles expand in size in the thief zone when they encounter a temperature at or greater than the transition temperature so as to reduce the permeability of the thief zone to water.
Patent AU-2018313149-A1 (AU)
Title: Chemically modified oligonucleotides
Inventor: ELISEEV ALEXEY
IPC: C07H21/02
Filed: 2018-08-07
Abstract: The disclosure relates, in some aspects, to methods and compositions for production of immunogenic compositions. In some embodiments, the disclosure provides host cells which have been treated ex vivo with one or more oligonucleotide agents capable of controlling and/or reducing the differentiation of the host cell. In some embodiments, compositions and methods described by the disclosure are useful as immunogenic modulators for treating cancer.
Patent AU-2018313260-A1 (AU)
Title: Methods and compositions relating to emulsions comprising fish oil and/or omega-3 fatty acids
Inventor: PUDER MARK
IPC: A23L33/115
Filed: 2018-08-10
Abstract: Described herein are emulsion compositions comprising fish oil and medium-chain triglycerides (MCT) and/or omega-3 fatty acids and medium-chain triglycerides (MCT). In some embodiments, the compositions further comprise, e.g., alpha-tocopherol, or one or more fatty acids. Further provided herein are methods of using the compositions, e.g., to provide nutrion, e.g., parenteral nutrition to a subject and/or to treat or prevent certain conditions described herein.
Patent AU-2018368558-A1 (AU)
Title: Soil release polymers and laundry detergent compositions containing them
Inventor: GREEN ANDREW DAVID
IPC: C11D3/37
Filed: 2018-11-15
Abstract: The invention provides a polymer providing soil release properties (also termed a "soil release polymer" or SRP) when incorporated in a laundry detergent composition, the polymer comprising a capped polyoxyalkylene end block connected to a polyester segment; the polyester segment comprising alternating -B
Patent AU-2018376923-A1 (AU)
Title: Stemless humeral anchoring component for a shoulder prosthesis humeral implant
Inventor: LEFEBVRE YVES
IPC: A61F2/40
Filed: 2018-11-27
Abstract: The invention relates to a stemless humoral anchoring component (1) for a shoulder prosthesis humoral implant, this stemless humoral anchoring component (1) comprising an anchoring stud (2) having anchoring wings (3, 4) extending radially at the periphery of the anchoring stud (2), wherein the anchoring wings (3, 4) are three in number, with one lateral anchoring wing (3) and two medial anchoring wings (4), and are angularly separated at an angle (AN) of between 110 and 130 degrees, and wherein the lateral anchoring wing (3) has a radially measured length greater than the radially measured lengths of the medial anchoring wings (4).
Patent AU-2018381369-A1 (AU)
Title: Composition
Inventor: SAITO TAKANORI
IPC: C11D3/37
Filed: 2018-12-05
Abstract: The present invention pertains to a composition for treating an object to improve washability. This composition contains a modified hydroxyalkyl cellulose, and at least one selected from an anionic surfactant or a nonionic surfactant. The modified hydroxyalkyl cellulose has a cationic group, and a hydrophobic group represented by formula (1), wherein the cationic group and the hydrophobic group are bonded to a group obtained by removing a hydrogen atom from a hydroxyl group of a hydroxyalkyl cellulose (in formula (1), Z represents a single bond, or a hydrocarbon group having oxygen atoms, R
Patent AU-2018382994-A1 (AU)
Title: Active breathing system
Inventor: VANNESTE VINCENT
IPC: A41D13/002
Filed: 2018-12-14
Abstract: The present invention relates to an active breathing system for a cleanroom suit, designed to be worn by a user, comprising a ventilation device and an air intake means, said active breathing system further comprising a cleanroom suit and optionally an undergarment.