baber/WOPTO huggingface dataset:
Patent CN-100474458-C (CN)
Title: 铜包铝扁线的制造方法
Inventor: LI FU
IPC: H01B5/00
Filed: 2007-09-11
Granted: 2009-04-01
Abstract: 本发明涉及一种铜包铝线生产方法，特别是一种铜包铝扁线的制造方法，其工艺步骤如下：(1)在惰性气体保护下铜铝包覆焊接；(2)经拉丝机的一系列拉丝模拉制，拉制时线的温度应低于240℃，并达到预定的总变形量；(3)装入有惰性气体保护的退火炉中进行限制扩散层退火，达到预定温度后，保温60-150分钟；(4)在轧辊直径与线径比相匹配的两辊平辊轧机上至少轧制一次，并达到预定尺寸；(5)在拉拔机上用矩形拉丝模进行成品拉拔，达到成品的几何尺寸；(6)在惰性气氛中进行软化退火、收线。具有节省铜材53-60%，性能稳定可靠，并把铜铝两者的优点有机融为一体，接触表面达到冶金结合，减轻自重。
Patent CN-100505262-C (CN)
Inventor: YUEHUI YU
IPC: H01L27/082
Filed: 2007-02-09
Granted: 2009-06-24
Abstract: 本发明公开了一种半导体脉冲功率开关及其制备方法。开关由晶闸管单元p + npn + 和晶体管单元n + npn + 相间排列而成，阳、阴极侧均设有Al电极；其阴极侧的n + 发射极的掺杂浓度为1×10 20 ～1×10 22 cm -3 ，结深为15～25μm，晶体管单元n + npn + 内的位于开关的阳极侧的n + 发射极的掺杂浓度为1×10 20 ～1×10 22 cm -3 ，结深为15～25μm，晶闸管单元p + npn + 的p + 发射极掺杂浓度为8×10 17 ～5×10 18 cm -3 ，结深为1～5μm。本发明采用的可减小开通电压的薄发射极RSD结构，包括减薄p + 发射区宽度和降低p + 发射区掺杂浓度两方面。本发明在n型Si衬底上进行Al烧结，形成RSD薄发射极的阳极结构。与现有薄发射极形成工艺相比，本发明保证了薄发射极不在后续工艺中被破坏，并且降低了对设备的要求，节省了工序，并且不会引起RSD阴极面反型。
Patent CN-100481144-C (CN)
Title: 基于无线射频的白蚁危害电子监控系统
Inventor: WENJUN LIU
IPC: G08C19/00
Filed: 2007-08-15
Granted: 2009-04-22
Abstract: 本发明基于无线射频的白蚁危害电子监控系统，包括有一个作为中央集中数据采集器的微处理器单元，其数据接口经有线通讯信道连通有至少一个数据终端接受单元，每个数据终端接受单元均经至少一个无线通讯信道连通相对应的具有信息处理功能和ZIGBEE无线通讯的模块，该模块又通过各自的数据线连接有各自的白蚁危害探测器中的白蚁危害监测探头，并接收来自所述白蚁危害监测探头所探测的白蚁危害信息；所述白蚁危害探测器具有ZIGBEE通讯功能和自适应组网功能。其采用ZIGBEE无线通讯数据采集方式代替常规接触式数据采集方式，并由多个具有信息处理功能和ZIGBEE无线通讯的模块能自适应组网，可最大限度地减低数据采集使用成本，节约电源供给线路费用及信息传输路径费用。
Patent CN-100476358-C (CN)
Inventor: JIANCHENG FANG
IPC: G01C19/56
Filed: 2007-08-06
Granted: 2009-04-08
Abstract: 一种MEMS陀螺仪的精密安装基准体组件及其安装方法，包括精密安装基准体和敏感轴水平的微型MEMS振动陀螺仪本体，陀螺仪本体嵌入到基准体内部凹陷空间里，基准体采用装配性能和二次加工性能优良的材料制成，组件通过第一基准面和第二基准面与载体连接。安装时先加工出基准体初型，并安装陀螺仪，再测试出陀螺的输入轴失准角，计算出安装偏角，然后根据偏角，修正安装基准体的基准面，使偏角趋向于零。本发明利用了基准体制备材料优良的装配性能和二次加工性能，通过加工和修正来提高陀螺安装精度，适用于各种通过电路板安装的敏感轴水平的微型陀螺仪，尤其适用于组成各种小型化运载体中惯性测量单元的微型MEMS振动陀螺仪。
Patent CN-100575907-C (CN)
Inventor: ZHANGFENG ZHAO
IPC: G01M17/007
Filed: 2008-09-29
Granted: 2009-12-30
Abstract: 一种小型作业机整机综合性能测试试验台，包括设备底座，在设备底座上安装电力测功部件和磁粉测功部件，电力测功机、第一扭矩转速传感器安装在设备底座上，电力测功机的输出轴与第一扭矩转速传感器连接，并通过第二联轴器与第一连接轴相接，第一连接轴安装在第一轴承座上，第一连接轴与被测物体间的动力接口连接；第一磁粉制动器、第二扭矩转速传感器安装在设备底座上，第一磁粉制动器的输出轴与第二扭矩转速传感器相连接，并通过第四联轴器与第二连接轴相接，第二连接轴安装在第二轴承座上，第二连接轴与被测物体间的动力接口连接；第一连接轴和第二连接轴的轴线位于同一直线上。本发明能够进行整机性能测试、适用性强。
Patent PT-1067829-E (PT)
Inventor: FORNSEL PETER
IPC: H05H1/34
Filed: 2000-06-29
Abstract: The plasma nozzle is designed so that the mouth (18) of the nozzle duct is curved in relation to the vertical axis (A). The housing (10) is rotatable about its axis (A). The housing (10) is located rotationally on a carrying tube (14). The counter electrode is formed by the housing (10).
Patent PT-1335651-E (PT)
Inventor: KNUDSEN OLE
IPC: A23L1/18
Filed: 2001-11-21
Abstract: A method is described in which expanded snack and breakfast cereal products are produced with durum wheat flour, durum semolina, durum granular or other products of Triticum Durum and which can be produced in a simple and quick process which, surprisingly, eliminates the disadvantages of prior art. Furthermore, the invention related to a product produced according to the new method.
Patent PT-1272720-E (PT)
Title: Cylinder lock with a cylinder housing and flange key for a cylinder lock
Inventor: PRUNBAUER KURT
IPC: E05B15/00
Filed: 2002-01-23
Abstract: A cylinder lock with a cylinder casing 1 and a rotatable cylinder core 2 comprises: a key channel 4 for receiving a flat key 5; followers [25, figure 1] for control faces on the key; locking parts which allow or prevent rotation of the cylinder core 2; and a slidable catch bar 26 located within the cylinder core 2 in a plane across the longitudinal centre plane [7, figure 1] of the cylinder lock. The catch bar 26 comprises a locking arm 27 positioned over the key channel and is movable by the edge of the key 5 and by the spring force 35 between locked and unlocked positions. When the key is only partially inserted in the key channel, a locking flank 30 on the key holds the locking arm in a locking recess 28 in the cylinder casing, thus preventing rotation of the core 2. When the key is fully inserted, as shown in figure 2, the locking arm is positioned opposite a free recess 29 on the key. Upon rotation of the key the locking arm 27 can enter the key recess 29. When the key is rotated, the recess 29 retains the key such that the key cannot be removed [figure 3].
Patent PT-1383899-E (PT)
Title: Enzymatic method for the enantioselective reduction of keto compounds
Inventor: GUPTA ANTJE
IPC: C12P7/62
Filed: 2002-04-15
Abstract: New enantioselective reduction method of keto compounds (I) comprises the use of an alcohol dehydrogenase (ADH) in a two-phase water-solvent system. New enantioselective reduction method of keto compounds of formula (I) comprises incubating with alcohol dehydrogenase (ADH) in a two-phase system of water, co-factor and organic solvent with log P (octanol-water partition coefficient) = 0.5-4, and then recovering chiral hydroxy compound (II). R 1>-CO-R 2> (I) R 1>, R 2>hydrogen, 1-20C linear or branched alkyl, 2-20C linear or branched alkenyl or alkynyl, with 1-4 unsaturated bonds, 6-14C aryl, or 6-14C aryl(1-8C) alkyl; CO+R 1>+R 2>6-14C aryl or 5-14C heterocycle, and all residues are optionally substituted by 1-3 of hydroxy, halo, nitro, 1-20C alkoxycarbonyl (alkyl linear or branched, optionally substituted by 1-3 of halo, hydroxy, amino or nitro) or 5-14C heterocycle, optionally substituted by 1-3 of halo, hydroxy, amino or nitro. Independent claims are also included for: (1) Alcohol dehydrogenase (ADH') from Lactobacillus minor having a 264 amino acid sequence (X), reproduced; (2) DNA sequence encoding (X); (3) Escherichia coli mutant DSM 14196; (4) Production (M1) of ADH' by recombinant expression of the corresponding DNA in prokaryotic or eukaryotic microorganisms; and (5) Preparation (M2) of (S)-hydroxy compounds (II) by incubating the racemate with ADH in the specified two-phase system.
Patent PT-1455770-E (PT)
Title: Use of norepinephrine reuptake inhibitors for the treatment of tic disorders
Inventor: ALLEN ALBERT JOHN
IPC: A61K31/135
Filed: 2002-11-12
Abstract: Selective norepinephrine reuptake inhibitors are used to treat tic disorders.
Patent PT-1421884-E (PT)
Title: Induction plate
Inventor: KLOPPSTECK GERD
IPC: A47J36/02
Filed: 2003-10-11
Abstract: The device (1) is assembled of a disk (11) maDEof an electromagnetic metal like a steel-chrome alloy and a handle (13), maDEof a heat insulated material. The handle (13) can be swiveled around a transversal axle formed by a wire (14) surrounding the outer edge of the disk (11) from a working into a storage position. A hole (13a) at one of the ends of the handle (13) facilitates the device (10) to be hung to a suitable object when not in use.
Patent PT-1394149-E (PT)
Inventor: ARMBRUSTER ERICH
IPC: C07D213/57
Filed: 2000-01-13
Abstract: 1-(6-Methylpyridin-3-yl)-2-(4-methylsulfonyl-phenyl)-ethanone is new.  1-(6-methylpyridin-3-yl)-2-(4-methylsulfonyl-phenyl)-ethanone of formula (I) is new:  Independent claims are also included for the following:  (a) a 4-step preparation of (I) where the third step for the preparation of N,N-dialkylamino-(6-methyl-3-pyridyl)acetonitriles of formula (III) and the last step are claimed per se;  (b) compounds (III);  (c) alkali metal 1-hydroxy-(6-methylpyridin-3-yl)methanesulfonate intermediates of formula (II) (for preparing (III)); (d) preparation of (II) comprising treating 2-methyl-5-vinylpyridine with ozone followed by reduction with an alkali hydrogen sulfite. R1, R2  =  1-4C alkyl;  M  =  alkali metal.
Patent PT-1539053-E (PT)
Title: Implant manipulation and storage tools
Inventor: ZIEBOL ROBERT
IPC: A61B17/56
Filed: 2003-09-12
Abstract: There is disclosed a manipulation and storage tool for receiving and manipulating a partially dehydrated intervertebral disk. Manipulation and storage tool is configured to receive the disk and manipulate it into a smaller overall size and subsequently insert it into a temporary storage or sleeve device for later use. Manipulation and storage tool generally includes a manipulation assembly which is movably mounted with respect to a guide assembly. The guide assembly includes a throughbore and a slot for receiving the disk into the throughbore as well as a sleeve holder mounted at a distal end designed to retain a storage device or sleeve into which the manipulated disk is inserted. The manipulation assembly generally includes a drive member having an elongated shaft movably mounted within the bore of the guide assembly and at least one manipulation member for pin positioned adjacent the slot to manipulate the implant in response to movement of the drive member relative to the guide assembly. Preferably, the drive member and guide assembly are inter-connected by a drive rod having a chive pin which guides the motion of drive member with respect to the guide assembly in response to rotation of the drive member to manipulate the disk and insert it into the sleeve. There is also disclosed an insertion tool for receiving an assembled sleeve and disk and inserting the manipulated disk into an intervertebral disk space. Methods of use of the manipulation and storage tool and the inserter tool are also disclosed. There is also disclosed an implant folding and storage device including an implant folding device having a pair of jaws configured to fold an implant therebetween. An implant transfer device is provided to move the folded implant from within the implant folding device and into an implantation tube. There is also disclosed a novel surgical instrument assembly for receipt of a folded implant and installation of the implant into a portion of the body.
Patent PT-1734971-E (PT)
Title: Polymer-based sustained release device
Inventor: WRIGHT STEVEN G
IPC: A61K9/16
Filed: 2004-04-15
Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
Patent PT-1783293-E (PT)
Title: Reinforced insulating body for a prefabricated insulated wall element and wall element and method of manufacture
Inventor: KRECKEL THOMAS
IPC: E04C2/04
Filed: 2006-07-22
Abstract: Reinforced insulating body has insulating plate (3) on which fixing elements (6) are arranged unilaterally and perpendicular to planar side (4). A spacer (10) is provided on the ends of fixing element distant to the insulating plates. One fixing element is eliminated from the insulating plate on the reinforcing mat (9). An independent claim is also included for a prefabricated wall.
Patent PT-1897545-E (PT)
Title: Tamper resistant oral pharmaceutical dosage forms comprising an opioid analgesic
Inventor: MANNION RICHARD OWEN
IPC: A61K9/32
Filed: 2007-08-24
Abstract: The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.
Patent PT-1882551-E (PT)
Title: Physical method of delustring
Inventor: IACOB CONSTANTIN
IPC: B24C3/18
Filed: 2007-07-26
Abstract: The method involves fluidizing particles in gas e.g. air, and liquid e.g. water, by a fluidized bed technique using a fluidizing chamber (1). A surface of articles (6) e.g. glass articles, is treated by subjecting the articles to a flow of the fluidized particles, where the particles have an average size that is equal to one micrometer. The speed of the flow of the particles ranges between 5 and 20 meters per second. The fluidized particles are collected during treating operation and/or post-treatment washing operation, and are recycled during fluidizing operation. An independent claim is also included for an installation for implementing a surface treating method.
Patent PT-2069598-E (PT)
Title: Door and/or window stopper
Inventor: MAYER F E FRANK
IPC: E05C17/54
Filed: 2007-10-01
Abstract: Disclosed is a door and/or window stopper comprising an outer contour that extends into a tip (25) and an inner hollow space (10) which, preferably, substantially matches said contour. As an external part (2), the outer edge of the stopper is made of rubber or a flexible, rubber-type thermoplastic material that has a relatively high coefficient of friction. A clip-type internal part (4) that is provided with two arms (12, 14) and has greater flexural rigidity than the external part (2) is disposed within the external part (2). In order to further develop said door and/or window stopper in such a way that the production is simplified, less material is used, and the weight is reduced, the wall thickness of at least one of the arms (12, 14) of the internal part (4) decreases towards the tip (24) such that the wall thickness (20) of the internal part (4) and/or the arm (12, 14) thereof is greater in the end region (28) than the wall thickness (22) in the tip (6) region of the internal part (4).
Patent PT-2133958-E (PT)
Title: Female plug for self-locking connector system
Inventor: ROBERT DAVID
IPC: H01R13/627
Filed: 2008-06-09
Abstract: The connector (1) has a tubular body (10) housing an insert (11) to accept ends of a signal conducting part. The ends of the signal conducting parts are connected to ends of other signal conducting part, and two positive or negative or alternating reliefs (12) of a self-locking system are located on a periphery of the insert, where the two positive or negative or alternating reliefs of the self-locking system are secured to the female connector. A plug is pushed into a socket in such a way that axial ribs (354) are indexed and slid in cuts. An independent claim is also included for a male connector comprising a locking part.
Patent PT-1997478-E (PT)
Title: Liquid formulations for the prevention and treatment of mucosal diseases and disorders
Inventor: JACOB JEREMY E
IPC: A61K9/00
Filed: 2002-02-15
Abstract: Stable, viscous, mucoadhesive aqueous compositions which are useful for the prevention and treatment of ulcerative, inflammatory, and/or erosive disorders of mucous membranes and/or the delivery of pharmaceutically active compounds to mucosal surfaces for topical treatment or transfer to the systemic circulation.
Patent PT-2135111-E (PT)
Title: Multicoloured telemetry
Inventor: ROUSSEAU PASCAL
IPC: G01S17/10
Filed: 2008-02-29
Abstract: The rangefinder has an emission device for emitting laser pulses of N different wavelengths, where N is an integer that is greater than one, and emission frequency for each wavelength is lesser than a preset threshold frequency. A detection device having an optical coupler (14) detects pulses reflected by a remote object, and an accumulating device accumulates the detected pulses. The emission device has a wideband amplifier (13) to amplify each of the emitted pulses, and emitters (10) e.g. laser diodes, each connected to an optical multiplexer (12) by an optical fiber (11).
Patent PT-2218270-E (PT)
Title: System and method for authenticating a context transfer
Inventor: NIEMI VALTTERI
IPC: H04W8/12
Filed: 2008-10-27
Abstract: The user equipment (UE) and the Mobility Management Entity (MME) in an evolved 3GPP system generate authentication material that can be carried inside a packet switched network temporary mobile station identifier (P-TMSI) signature field of a Universal Mobile Telecommunications System (UMTS) signaling message from the UE to a UMTS/GPRS serving GPRS support node (SGSN) in a UMTS or GPRS Terrestrial Radio Access Network (UTRAN) or in a GSM/Edge Radio Access Network (GERAN), as well as from the SGSN to the MME of the evolved 3GPP system. The MME authenticates a context transfer request from the UTRAN/GERAN system based on the transferred authentication material and knowledge of how to create or to verify the authentication material. Additionally, the MME and the UE derive or verify authentication material, based on at least one user-specific key, for embedding in the P-TMSI signature field in legacy 3GPP signalling.
Patent PT-2345653-E (PT)
Title: Morphinan compounds
Inventor: TUNG ROGER
IPC: C07D471/08
Filed: 2008-04-30
Abstract: This disclosure relates to novel morphinan compounds and their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This disclosure also provides compositions comprising a compound of this disclosure and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a Ã1 receptor agonist that also has NMDA antagonist activity.
Patent PT-574347-E (PT)
Inventor: VISSER JACOB
IPC: C12N1/19
Filed: 1993-04-06
Abstract: The present invention concerns a novel DNA sequence coding for an Aspergillus serine protease of the subtilisin-type, an Aspergillus serine protease of the subtilisin-type per se and a method for the preparation thereof. The invention further concerns a novel Aspergillus mutant strain defective in a serine protease of the subtilisin-type, which is useful for the expression of heterologous protein, and a method for the preparation of such a mutant strain.
Patent PT-749323-E (PT)
Inventor: BOUSSIOTIS VASSILIKI A
IPC: A61P31/00
Filed: 1995-03-08
Abstract: Methods for modulating antigen-specific T cell unresponsiveness which involve inhibiting or stimulating an unresponsive T cell though a cell surface receptor, CD2, are disclosed. Agents which inhibit stimulation of an unresponsive T cell through a CD2 surface receptor are useful therapeutically in situations where it is desirable to inhibit an immune response to an antigen(s), for example in organ or bone marrow transplantation and autoimmune diseases. Methods for reversing T cell unresponsiveness by contacting the T cell with an agent which stimulates the T cell through a CD2 surface receptor are useful therapeutically to stimulate an immune response to an antigen(s). For example, the method is useful to stimulate an anti-tumor response in a subject with a tumor or stimulate a response against a pathogenic agent or increase the efficacy of vaccination.
Patent PT-790974-E (PT)
Inventor: WOLANIN DONALD JOHN
IPC: C07C271/28
Filed: 1995-11-09
Abstract: Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The presently claimed compounds have the generalized formula   <IMAGE>   in which each T represents a substituent group; x is 0, 1, or 2; D represents   <IMAGE>    delta  is 0 or 1; U' represents O, S, or N, with the proviso that when U' is N, then  delta =0, and when U' is O or S, then  delta =1; R14 is any of a variety of substituent groups; and G represents M,   <IMAGE>   in which M represents -CO2H, -CON(R11)2, or -CO2R12, R11 represents H or an alkyl group, R12 represents an alkyl group, and R13 represents any of the side chains of the 19 noncyclic naturally occurring amino acids; and pharmaceutically acceptable salts thereof.
Patent PT-830253-E (PT)
Inventor: WHITAKER TYSON BAILEY
IPC: B41J29/02
Filed: 1996-06-03
Abstract: A printer (10) housed in an accessible drive bay of a computer. The computer including media access (12) for inserting media to be printed into the printer, a communication link for receiving image data, a printhead for printing on the media, and means for mounting the printer in the bay. Also, a personal computer includes a housing, an accessible drive bay in the housing, a central processing unit, memory, a data retrieval and storage device, at least one connection for an input/output device, a power supply, and a printer, wherein the printer is housed within the drive bay.
Patent PT-862528-E (PT)
Inventor: BIEKER GUIDO
IPC: B61F5/14
Filed: 1997-10-11
Abstract: A rail vehicle, includes an air-suspended body having an underside, an air spring having a base point and an internal air pressure, and cars supporting the body. The body rests on the cars and swings out on the air spring. There is also an emergency spring which has a core. Guide and damping devices are further disposed between the body and the cars. The guide and damping devices serve to stabilize the cars at traveling speeds of >100 km/h and suppress any sway of the cars. The guide and damping devices include a friction plate loaded against the underside of the body by the internal air pressure of the air spring. The friction plate is linked to the core of the emergency spring or the base point of the air spring to form a connection to the cars in a longitudinal direction for suppressing the sway of the cars.
Patent PT-904061-E (PT)
Inventor: ESTANOVE CYRIL
IPC: A61K47/20
Filed: 1997-12-23
Abstract: PCT No. PCT/FR97/02403 Sec. 371 Date Aug. 20, 1998 Sec. 102(e) Date Aug. 20, 1998 PCT Filed Dec. 23, 1997 PCT Pub. No. WO98/27965 PCT Pub. Date Jul. 2, 1998Provided is a pharmaceutical composition based on rhein or diacerhein. The composition is intended for administration by the oral, rectal or cutaneous (percutaneous or transdermal) route, and comprises rhein or diacerhein, or one of their pharmaceutically acceptable salts or esters, and sodium lauryl sulfate, comicronized, in a weight ratio between 3:1 and 30:1. The composition exhibits improved bioavailability.
Patent PT-1079807-E (PT)
Title: Use of preparations for the application of antiseptic agents and/or agents promoting the healing of wounds to the lower respiratory tract
Inventor: FLEISCHER WOLFGANG
IPC: A61K9/51
Filed: 1999-05-27
Abstract: Use of an anti-inflammatory agent such as povidone iodine for the preparation of a pharmaceutical composition for the treatment of diseases of the lower respiratory tract which are susceptible to the administration of such agents.
Patent PT-1119659-E (PT)
Inventor: KAY JOHN GRANVILLE
IPC: E04F15/10
Filed: 1999-10-11
Abstract: A floor covering material (1) comprising a PVC layer (3) having embedded aggregate (6) for providing surface roughness. The material incorporates a barrier layer (4) of polymeric material other than PVC fused into the upper surface of the PVC layer (3), the aggregate (6) being exposed at the surface of the barrier layer (4).
Patent IE-39150-L (IE)
Title: Prosthetic hip joint devices.
IPC: A61F2/30
Filed: 1974-01-04
Abstract: 1446773 Prosthetic hip joints NATIONAL RESEARCH DEVELOPMENT CORP 3 Jan 1974 [12 Jan 1973] 1790/73 Heading ASR A prosthetic hip joint comprises a femoral head replacement component 1 having an elongated tapered intermedullary stem 2 and a ball-shaped head 4 for use in articulating engagement with a prosthetic acetabular socket, and a larger ball-shaped head assembly 5 demountably securable around the head 4 to modify the component 1 for articulating engagement with a natural acetabular socket. The assembly 5 comprises integral inner and outer caps 6a, 6b, of plastics and metal respectively, mounted to head 4 by two semi-annular shells 7 engaging a necked portion 3 of component 1 and an annular groove 6c in cap 6a, the assembly being retained on the head 4 by screws 10 carried in bores 8. The groove 6c may be provided with flats engaging corresponding portions of the shells 7 to prevent mutual rotation.
[GB1446773A]
Patent IE-900200-L (IE)
Title: Avermectin derivatives
IPC: A61P33/10
Filed: 1990-01-18
Abstract: Novel avermectin derivatives of formula (I) are disclosed, wherein the 5-hydroxy group is replaced by an oxime group. The avermectin-5-oximes can further be derivatized at the 4"- or 4'-positions as amino, substituted amino, acylhydrazone, semicarbazone, or substituted semicarbazone analogues. The avermectin-5-oximes are prepared by the oxidation of the 5-hydroxy compounds with manganese dioxide or with pyridinium dichromate to the known 5-oxo analogues, and these are then reacted with a hydroxylamine salt. The new compounds are potent anti-parasitic agents, in particular, the compounds are anthelmintic, insecticidal and acaricidal agents.