baber/WOPTO huggingface dataset:
Patent CA-2498492-A1 (CA)
Inventor: PATTERSON MICHAEL R
IPC: A43C15/06
Filed: 2005-02-16
Abstract: An ice safety walking aide device with retractable spikes, this device to be attached beneath the arch of a boot bottom, to help prevent accident on slippery surfaces, example freezing rain and other icy conditions, said device including spikes securely concealed inside said device, which can easily protrude to contact a slippery surface whenever attached to a boot bottom, and further automatically retracts when not attached. Solid side barriers prevents slipping and twisting, a strap with quick releasable buckle can secure the device to a person's boot. The safety walking aide device is sturdy, convenient and is capable to prevent many accidents onto side walks, parking lots and other slippery areas onto thick and thin ice.
Patent CA-2500824-A1 (CA)
Title: Tricyclic tetrahydroquinoline antibacterial agents
Inventor: SHERRY DEBRA ANN
IPC: C07D498/20
Filed: 2003-10-03
Abstract: The invention includes tetrahydroquinoline and related compounds of formula (I), and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogen s.
Patent CA-2501061-A1 (CA)
Title: Protein labelling with o6-alkylguanine-dna alkyltransferase
Inventor: JUILLERAT ALEXANDRE
IPC: C12N15/62
Filed: 2003-10-01
Abstract: The present invention relates to methods of transferring a label from suitab le substrates to O6-alkylguanine-DNA alkyltransferase (AGT) fusion proteins, to suitable fusion proteins, to suitable variants of AGT, and to novel labelled fusion proteins obtained. A protein of interest is incorporated into an AGT fusion protein, the AGT fusion protein is contacted with an AGT substrate carrying a label, and the AGT fusion protein is detected and/or manipulated using the label in a system designed for recognising and/or handling the lab el.
Patent CA-2501368-A1 (CA)
Title: Methods and devices for source controlled variable bit-rate wideband speech coding
Inventor: JELINEK MILAN
IPC: G10L25/90
Filed: 2003-10-09
Abstract: Speech signal classification and encoding systems and methods are disclosed herein. The signal classification is done in three steps each of them discriminating a specific signal class. First, a voice activity detector (VAD) discriminates between active and inactive speech frames. If an inactive speech frame is detected (background noise signal) then the classification chain ends and the frame is encoded with comfort noise generation (CNG). If an active speech frame is detected, the frame is subjected to a second classifier dedicated to discriminate unvoiced frames. If the classifier classifies the frame as unvoiced speech signal, the classification chain ends, and the frame is encoded using a coding method optimized for unvoiced signals. Otherwise, the speech frame is passed through to the "stable voiced" classification module. If the frame is classified as stable voiced frame, then the frame is encoded using a coding method optimized for stable voiced signals. Otherwise, the frame is likely to contain a non-stationary speech segment such as a voiced onset or rapidly evolving voiced speech signal. In this case a general-purpose speech coder is used at a high bit rate for sustaining good subjective quality .
Patent CA-2503843-A1 (CA)
Title: Generateur pour appareil d'electrochirurgie et procede de contre-verification de la fonctionnalite de mode
Inventor: REFIOR TIM
IPC: A61B17/00
Filed: 2003-10-27
Abstract: La présente invention a trait à un procédé d'évaluation de la fonctionnalité et du mode de fonctionnement d'un générateur pour appareil d'électrochirurgie par la détermination de la participation ou non telle que prévue d'un signal d'impulsion configuré dans la génération d'énergie requise pour l'électrochirurgie. On compare un certain nombre d'impulsions dans le signal d'impulsion configuré à un nombre prévu d'impulsions, et on détermine une condition d'erreur lorsque les deux valeurs ne sont pas identiques ou sont différentes d'une quantité supérieure à une quantité prédéterminée. Le nombre d'impulsions prévu dépend d'un mode de fonctionnement du générateur pour l'appareil d'électrochirurgie. La condition d'erreur peut servir de base pour l'arrêt de la distribution d'énergie en sortie.
Patent CA-2505499-A1 (CA)
Inventor: CHEN YURONG
IPC: A01H4/00
Filed: 2002-11-06
Abstract: L'invention concerne la mise au point d'un système de production et d'un système de transformation génétique de dihaploïdes, efficaces et économiques, permettant d'obtenir le déclenchement de la reproduction et la modification génétique de dihaploïdes chez le lin, respectivement. La culture préalable d'anthères sur un substrat renfermant de grandes concentrations de sel minéral et d'auxine, hautement osmotique, pendant un laps de temps donné, avant leur transfert vers un substrat renfermant de faibles concentrations de sel et d'auxine, faiblement osmotique, permet d'augmenter sensiblement l'efficacité globale de la régénération et l'efficacité des anthères par rapport à une mise en culture directe des anthères sur un substrat renfermant de faibles concentrations de sel et d'auxine, faiblement osmotique. Ce processus de culture permet également de réduire sensiblement la fréquence de régénération des pousses à partir de cellules somatiques dans la culture d'anthères. Ce processus a permis de mettre au point un système de transformation par cal obtenu par culture d'anthères hautement efficace. L'efficacité de transformation du système de transformation par cal obtenu par culture d'anthères est quatre fois supérieure aux meilleurs résultats de transformation obtenus à l'aide d'hypocotyles comme explants dans le système de transformation par Agrobacterium tumefaciens ou le système de transformations par bombardement de particules. La fréquence d'échappement dans le système de transformation par cal obtenu par culture d'anthères correspondait à un tiers de celle du système de transformation par hypocotyles à l'aide de A. tumefaciens ou à la moitié par bombardement de particules. Ce système de transformation hautement efficace est destiné à la recherche de base pour la découverte de gènes et à des applications pratiques du génie génétique pour des caractères améliorés.
Patent CA-2508897-A1 (CA)
Title: Process for manufacture of a composition for supplementing animals with solutions of essential metal amino acid complexes
Inventor: ANDERSON MICHAEL D
IPC: A61K33/24
Filed: 2003-10-28
Abstract: A process for preparation of stable, liquid solutions of complexes of trace elements and amino acid complexes of L-lysine, glycine, leucine, and serine.  The resulting complexes are used to supplement domestic animals nutritionally.  Since the solutions are stable, they can be used as a top drench or in drinking water.
Patent CA-2509315-A1 (CA)
Title: Process for the continuous production of longitudinally welded metal tubes
Inventor: BRUENN RAINER
IPC: B23K9/00
Filed: 2005-06-08
Abstract: A process for the continuous production of longitudinally welded metal tubes is described, wherein a metal strip (1) is drawn from a strip supply and gradually shaped into a slit tube in a shaping station (2), the slit tube is welded in a welding system (4) along the edges of the strip, and the welded tube (6) is extracted by an extraction device (5).  The welding system (4) is a protective gas arc welding system with several electrodes supplied by separate sources (4c, 4d) of welding current. The electrodes are arranged in succession in the direction of production. The welding system (4) has two welding devices (4a, 4b), whose electrode tips are directed at a common welding point. Only one of the welding devices (4a, 4b) is in operation at any given time, while the other welding device is in a standby position. When an electrode change becomes necessary, the arc of the welding device in the standby position is first struck by means of an auxiliary arc. The welding current intensity of the welding device presently in operation is then reduced, while the welding current intensity of the welding device in the standby position is simultaneously increased.
Patent CA-2510153-A1 (CA)
Inventor: YOUNG JAMES D
IPC: F16H57/00
Filed: 2003-12-19
Abstract: Un ensemble de pignons asymétriques (AS) comprend un corps de pignons (110) comportant : (i) des premier et second moyeux (116a, 116b) saillant axialement vers l'extérieur des première et deuxième faces axiales opposées (114a, 114b); et, (ii) plusieurs dents (120) qui s'étendent sur la circonférence en rangée, et qui saillent radialement vers l'extérieur entre les premier et second moyeux. Chaque dent comporte un flanc d'entraînement (124) et un flanc de côte (126). Les flancs d'entraînement et de côte d'au moins certaines dents présentent des formes différentes, si bien qu'un profil de dent asymétrique est formé. Des première et seconde bagues coussinets métalliques (112a, 112b) sont capturées et flottent de manière excentrique respectivement sur les premier et second moyeux. Les dents sont identiques ou des profils asymétriques multiples sont utilisés sur un seul corps de pignon et sont disposées selon un motif régulier ou irrégulier. La surface de pied entre les dents successives peut être allégée de sorte qu'un espace soit défini entre celle-ci et un galet qui fait la liaison avec le pied.
Patent CA-2512249-A1 (CA)
Title: Compositions of polymerized wheat proteins and ethanolamine derivatives
Inventor: MORELLI MURIEL
IPC: A61Q19/08
Filed: 2004-01-06
Abstract: This invention relates to compositions comprising an ethanolamine derivative and a polymerized wheat protein. It further relates to the use of such compositions in topical formulations, in particular in anti-aging formulations. The invention further relates to the use of such compositions to combat the effects of skin aging.
Patent CA-2512680-A1 (CA)
Title: Stabilized lyophilized compositions comprising tissue factor pathway inhibitor or tissue factor pathway inhibitor variants
Inventor: HORA MANINDER
IPC: A61K31/715
Filed: 2004-01-08
Abstract: Lyophilized compositions of TFPI or a TFPI variant suitable for long-term storage can be formed by lyophilizing an aqueous formulation of the TFPI or TFPI variant having a pH from about 4 to about 8 with a carbohydrate or amino acid glass forming agent. These lyophilized compositions are stable for greater than three months when stored at 40° C.
Patent CA-2514203-A1 (CA)
Title: Dental whitening apparatus
Inventor: CREAMER ALAN A
IPC: A61C19/06
Filed: 2004-08-25
Abstract: A dental whitening composition is formed from tablet formulation containing a metal ion catalyst and an alkaline pH raising compound and a peroxide solution having a concentration of about 1 percent to about 15 percent peroxide. The combination of the tablet formulation containing the metal ion within an alkaline composition along with the peroxide rinse forms a dental composition having foam like consistency, which whitens the surface of teeth. The tablet formulation can also be in the form of a gel or solution. The process of whitening teeth is accelerated by using a light emitting device producing a selected wavelength range. The light emitting device can be incorporated into a dental tray having a dental receiving area formed from a polymer having optical properties.
Patent CA-2514582-A1 (CA)
Inventor: HILLEN HEINZ
IPC: A61K38/17
Filed: 2004-02-02
Abstract: The invention relates to neuromodulatory oligomers of the amyloid-.beta.(1-42) protein, a particular production method, by means of which the oligomer can be obtained in a reproducible manner at high yield, the use of the oligomers as diagnostic and therapeutics agents, for the generation of oligomer-specific antibodies and for the discovery of substances which can interact with the oligomers and in the formation thereof. Corresponding methods for the production of the antibodies and for discovery of the substances are also disclosed as are the antibodies themselves and the use of the antibodies or substances as diagnostic and therapeutic agents. The invention further relates to derivatives of the oligomers and oligomers based on abbreviated forms of the amyloid-.beta.(1-42) proteins, the production and use thereof.
Patent CA-2515554-A1 (CA)
Title: Oligomeric compounds for the modulation of thioredoxin expression
Inventor: THRUE CHARLOTTE ALBAEK
IPC: C12N15/113
Filed: 2004-02-10
Abstract: Oligonucleotides directed against the TRX gene are provided for modulating the expression of TRX. The compositions comprise oligonucleotides, particularly antisense oligonucleotides, targeted to nucleic acids encoding the TRX.  Methods of using these compounds for modulation of TRX expression and for the treatment of diseases associated with either overexpression of TRX, expression of mutated TRX or both are provided. Examples of diseases are cancer such as lung, colon, prostate, pancreas, lung, liver, thyroid, kidney, brain, testes, stomach, intestine, bowel, spinal cord, sinuses, bladder, urinary tract or ovaries cancers. The oligonucleotides may be composed of deoxyribonucleosides or a nucleic acid analogue such as for example locked nucleic acid or a combination thereof.
Patent CA-2516080-A1 (CA)
Title: Inhibitors of antigen presentation by mhc class ii molecules and methods of use thereof
Inventor: SELF CHRISTOPHER R
IPC: C07K7/06
Filed: 2004-02-13
Abstract: The present invention relates to compounds, pharmaceutical compositions containing such compounds and methods for their use. In particular, the compounds of the invention are useful for the treatment or prevention of diseases associated with T cell proliferation such as autoimmune diseases and disorders.
Patent CA-2516131-A1 (CA)
Inventor: SORENSEN FRED
IPC: B62D1/187
Filed: 2005-08-17
Abstract: A pivot-mounted tilt lever of the type used with a conventional cam-actuated tilt lock arm in an automotive steering column, the tilt lever being molded as a monolithic body of thermosetting polymer material such as phenolic resin. The tilt lever has a cam release surface for operating the tilt lock arm in the steering column, the cam surface being formed from the thermosetting polymer material as an integrally molded and finished part of the monolithic body. A method for making the tilt lever as a monolithic body is also claimed.
Patent CA-2519733-A1 (CA)
Title: Indazole having analgesic activity
Inventor: POLENZANI LORENZO
IPC: A61P29/00
Filed: 2004-04-23
Abstract: An indazole having analgesic activity, a method for the preparation thereof and a pharmaceutical composition containing the same; the indazole has the following general formula: where X, Ra, Rb, Rc and Rd have the meanings stated in the description.
Patent CA-2520314-A1 (CA)
Inventor: CINOTTI ANDREA
IPC: B65G19/20
Filed: 2005-10-05
Abstract: A conveyor device, in particular for an automatic packaging machine for paper rolls, comprising: - a horizontal plane of advance (12), - at least one pair of motorised flexible transmission members (22, 24) extending along a closed loop and bearing a plurality of transverse bars (26, 28) fastened to said flexible transmission members (22, 24), - a plurality of thruster elements (32, 34) borne by said bars (26, 28), and - a stationary adjustment station (38) provided with at least one adjustment assembly (50) having a grip organ (52) movable in transverse direction and arranged in such a way as to displace in the transverse direction along the respective bar (26, 28) a thruster element (32, 34) positioned at the grip organ.
Patent CA-2521876-A1 (CA)
Title: Method of defining the differentiation grade of tumor
Inventor: HAMADA KENJI
IPC: C12Q1/68
Filed: 2003-04-08
Abstract: The present invention relates to a method of defining the differentiation grade of tumor by selecting genes and/or proteins whose expression level correlates with each differentiation grade of tumor, measuring the expression of the genes and/or proteins of human tumor tissues in each differentiation grade. The present invention also relates to the use of these genes and/or proteins for diagnosing the differentiation grade of tumor and for screening anti-cancer agents for tumor treatment.
Patent CA-2522113-A1 (CA)
Title: Grinding disc for grinding machines
Inventor: FALK ULRICH
IPC: B24B55/10
Filed: 2004-07-14
Abstract: The invention relates to a grinding disc (100) for being rotationally driven on a drive shaft of a grinding machine, particularly of a hand-guided grinding machine, comprising at least one supporting plate (10) with at least one hole or opening (20) through which grinding dust (300) resulting during grinding can be suctioned by means of at least one suction bell located in or on the grinding machine. Said hole or opening (20) is aerodynamically designed.
Patent CA-2522381-A1 (CA)
Title: Apparatus for packing free terminal convolutions of spring assembly used in mattress
Inventor: AHN SUNG-HO
IPC: A47C27/06
Filed: 2004-06-30
Abstract: There is provided an innerspring assembly used in a mattress for absorbing external loads. An outermost coil spring (115) of a spring array (110) is secured in a space between upper and lower border wires (120 and 120') by pins (140), and helical coils (130) are disposed in row directions (R) on upper and lower portions of the spring array (110) to knit an adjacent coil spring (115), such that each coil spring has a free terminal convolution (115a) protruded from an upper portion of the upper border wire (120) and/or a lower portion of the lower border wire (120'). The spring assembly includes an enclosure (10) partially or fully provided on an upper end portion and/or an lower end portion of the coil spring for covering the terminal convolution (115a) in the row direction (R) or column direction (L), thereby interrupting interference between the terminal convolution (115a) and the upper and/or lower border wire (120 and 120') and absorbing a lateral load applied to the terminal convolution. A padding member is not damaged by the terminal convolution, and a contact resistance between the upper border wire and the terminal convolution is absorbed to block a frictional noise.
Patent CA-2522951-A1 (CA)
Inventor: WARMBOLD DAVID A
IPC: A61F2/28
Filed: 2004-03-19
Abstract: An interbody spacer (20) includes concave lateral surfaces (30,36) extending at an angle (A1) with respect to the longitudinal axis (L1). In one aspect, the interbody spacer includes upper and lower convex surfaces (22,24) defined by an arc extending from a center point offset from the spacer midpoint (M).  In another aspect, lateral edges (21,23) of the upper and lower surfaces are also defined by convex arcs extending from a center point offset from the spacer midpoint.
Patent CA-2524504-A1 (CA)
Inventor: WHITE MATTHEW D
IPC: B29C45/00
Filed: 2005-10-26
Abstract: A sill assembly includes an integral sill assembly having a sill base and an inclined threshold. The sill base is overmolded in an injection molding process onto the inclined threshold. A rail assembly is adjustably secured to the sill base.
Patent CA-2524753-A1 (CA)
Title: Evaluating storage options
Inventor: BRUNTON GREG M
IPC: G06F11/34
Filed: 2004-06-24
Abstract: Evaluating storage options includes identifying workload descriptors associated with a storage instance, where each workload descriptor corresponds to a data characteristic, and where the storage instance has one or more storage attributes. For each workload descriptor of the plurality of workload descriptors a workload descriptor is selected. A weight and a workload parameter value is associated with the selected workload descriptor, where the weight represents an impact of the workload parameter value on a storage attribute of the storage instance. One or more storage options are evaluated in accordance with the weight and the workload parameter value. A storage option from the one or more storage options is determined for the storage instance according to the evaluation of the one or more storage options.
Patent CA-2524813-A1 (CA)
Inventor: MOORE MICHAEL J
IPC: H05K7/20
Filed: 2005-10-31
Abstract: A refrigeration system for use in cooling electronic equipment includes a closed vapor compression circuit having operably disposed therein a compressor, a condenser, a first expansion device, a second expansion device, and a two-part evaporator. A first part of the evaporator receives working fluid from the first expansion device at a first pressure, and a second part of the evaporator receives working fluid from the second expansion devi ce at a second pressure that is different than the first pressure.
Patent CA-2527121-A1 (CA)
Title: Formulations of non-steroidal anti-inflammatory agents to treat pathologic ocular angiogenesis
Inventor: BINGAMAN DAVID P
IPC: A61K31/19
Filed: 2004-06-14
Abstract: Methods for the use of NSAIs in combination with anecortave acetate are disclosed for preventing and treating pathologic ocular angiogenesis and associated edema, retinal edema, PPDR or NPDR.
Patent CA-2527457-A1 (CA)
Inventor: WONG WAI MING RAYMOND
IPC: F24C15/00
Filed: 2005-11-17
Abstract: A self-supporting removable box-like liner for use in an electric oven that has a heating element supported in a plane and extending across a cooking chamber from one said side wall to the other. The liner has an open the front, a pair of liner side walls and a back wall, and an elongate aperture extending across the back wall and continuing along each liner side wall toward the front to pass over and receive the heating element such that the liner can be inserted into the chamber for use and completely removed for cleaning, without removal of the heating element from the oven.
Patent CA-2527785-A1 (CA)
Inventor: BISSKY GERMAN
IPC: C09K23/16
Filed: 2004-05-28
Abstract: The invention relates to salts comprising thiouronium cations or uronium cations, methods for the production thereof, and the use thereof as ionic liquids.
Patent CA-2529040-A1 (CA)
Title: Improving accuracy in searching digital ink
Inventor: LAPSTUN PAUL
IPC: G06F40/00
Filed: 2004-08-16
Abstract: A method and system for improving the accuracy of digital ink (310) searches is disclosed. The method includes receiving a search input query (370) from a user via a user terminal and determining a specialized format of digital ink, by a variety of means, then, based on the determined specialized format of digital ink, a digital ink searching algorithm is selected. A search (380) of a digital ink database (350) can then be performed for a match to the search input query (370) by utilising the digital ink searching algorithm, which is selected from a variety of algorithms so as to improve the accuracy of the search.
Patent CA-2529752-A1 (CA)
Title: Polypeptide transduction and fusogenic peptides
Inventor: WADIA JEHANGIR S
IPC: C07K14/16
Filed: 2004-06-18
Abstract: Due to the barrier imposed by the cell membrane, delivery of macromolecules in excess of 500 Daltons directly into cells remains problematic. However, proteins, which have been evolutionarily selected to perform specific functions, are therefore an attractive therapeutic agent to treat a variety of human diseases. In practice, the direct intracellular delivery of these proteins has, until recently, been difficult to achieve due primarily to the bioavailability barrier of the plasma membrane, which effectively prevents the uptake of the majority of peptides and proteins by limiting their passive entry. However, recent work using small cationic peptides, termed protein transduction domains (PTDs), derived from polynucleotide binding proteins, such as HIV TAT protein or the Drosophila transcription factor Antp. or synthetic poly-Arginine, have now been shown to deliver a myriad of molecules, including synthetic small molecules, peptides and proteins, into animal models in vivo.
Patent CA-2530253-A1 (CA)
Inventor: WEGENER DIRK
IPC: C08J5/00
Filed: 2005-12-14
Abstract: The present invention relates to plastic moldings that are prepared from optionally filled polyurethanes. The plastic molding of the present invention exhibit high tenacity, flexural strength and heat stability. This invention also relates to a process for the preparation of these plastic moldings and specifically to a process for the production of large parts comprising these plastic moldings.