baber/WOPTO huggingface dataset:
Patent UY-24063-A1 (UY)
Title: Empleo de concentrados con contenido de factor von willebrand (vwf) como terapia de combinacion en la terapia con antitromboticos y fibrinoliticos
Inventor: GERHARD DICKNEITE
IPC: A61K38/37
Filed: 1995-10-16
Abstract: Empleo de vWF o fragmentos con actividad vWF para la preparación de un agente que actúa como antídoto en hemorragias producidas por la administración de agentes antitrombóticos y/o fibrinolíticos. Es de alcance una composición farmacéutica que en calidad de componente A, contiene un agente antitrombótico y/o un agente fibrinolítico, y en calidad de componente B contiene vWF o fragmentos con actividad vWF; donde los componentes de esta composición están presentes en formas de dosificación unitarias separadas.
Patent UY-24997-A1 (UY)
Title: Nuevos derivados de triazole, procedimiento para su preparacion y composiciones farmaceuticas que lo contienen
Inventor: DANIELLE GULLY
IPC: A61K31/41
Filed: 1998-05-12
Abstract: La presente invención se refiere a derivados de triazole de fórmula (I), en la que: R1 representa alquilo, un grupo -(CH2)n-G donde n varía de 0 a 5 y G representa un grupo hidrocarbonado mono- o policíclico no aromático, un grupo -(CH2)nNR2R3 en el cual n representa un número entero de 1 a 6 y R2 y R3 idénticos o diferentes representan un alquilo o constituyen con el átomo de N al cual están unidos un grupo morfolino, piperidino, pirrolidinilo o piperazinilo; X1, X2, X3 o X4 representan cada uno independientemente, un átomo de H, de halógeno, un alquilo, un alcoxi o un trifluorometilo; R4 representa H, alquilo, un grupo -(CH2)nCOOR5 en el cual n es tal como se definió anteriormente y R5 representa H, alquilo o aril-alquilo, un grupo -(CH2)nOR5 o un grupo -(CH2)nNR2R3 en los cuales n, R2, R3 y R5 son tal como se los ha definido precedentemente, un grupo -(CH2)n-tetrazolilo en el cual n es como se definió anteriormente, o R4 representa uno de esos grupos en forma de sal de un metal alcalino o alcalinotérreo; Y1, Y2 e Y3 representan independientemente, H, halógeno, alquilo, alcoxi, nitro, ciano, acilamino, carbamoilo, trifluorometilo, un grupo COOR6 en el cual R6 representa H o alquilo; o una de sus sales o solvatos. Asimismo, se reivindica un procedimiento para su preparación, y composiciones farmacéuticas que los contienen. Dichos compuestos son agonistas de los receptores CCK-A (colecistoquinina-A), y por tanto son útiles en el tratamiento de desórdenes alimenticios, disquinesis tardía y trastornos gastrointestinales. Ej. no limitante: 2-[N-[5-(4-cloro-2,5-dimetoxifenil)-1-(2-ciclohexiletil)-1H-1,2,4-triazol-3-il]carbamoilo]-4,5-dimetil-1-[3-(2H-1,2,3,4-tetrazol-5-il)propil]-1H-indol
Patent UY-25208-A1 (UY)
Title: Métodos de tratamiento de cápsulas y formulaciones farmacéuticas secas y pulverizadas
Inventor: STEVEN HORHOTA
IPC: A61K9/14
Filed: 1998-10-14
Abstract: La presente invención enfoca los problemas de retención de la formulación en polvo en las cápsulas, proporcionando un medio para minimizar la cantidad de polvo retenida en las cápsulas después de la inhalación, aumentando con ello la cantidad de fármaco activo que alcanza los pulmones del paciente, al tiempo que se mejora su reproducibilidad. También se proporciona un medio para controlar el nivel de humedad de las cápsulas. Por lo tanto dicha invención proporciona un método para retirar materiales indeseables solubles en fluidos súper críticos del interior del cuerpo o tapa o ambos de una cápsula rígida, utilizada para almacenar una formulación seca pulverizada para inhalación, hecha de material duro que comprende las etapas de exponer tanto el cuerpo como la tapa o ambas de dicha cápsula a un fluido súper crítico. Dicho fluido súper crítico tiene una temperatura crítica menor de 200ºC y una presión crítica menor de 10000 PSI. Se consigue con ello que los materiales indeseables solubles en el fluido súper crítico pasen al mismo desde el cuerpo, la tapa o ambas partes de la cápsula. La formulación farmacéutica para inhalación comprende: bromuro de ipratropio, bromuro de tiotropio, bromuro de oxitropio, albuterol, sulfato de albuterol, clenbuterol, fenoterol, dipropionato de beclometasona, glucosa o lactosa. El fluido súper crítico es dióxido de carbono y uno o más solventes orgánicos. Las cápsulas rígidas citadas son hechas de gelatina, celulosa, plástico o una mezcla de dichos materiales.
Patent UY-25970-A1 (UY)
Inventor: YOSHIDA KIYOSHI
IPC: C07D209/12
Filed: 2000-01-17
Abstract: The present invention relates to an indole derivative represented by formula (1) or a salt thereof, and a pharmaceutical containing the derivative or the salt: <CHEM> Äwherein R<1> represents lower alkyl; R<2> represents hydrogen or phenyl which may be substituted by at least one lower alkyl, lower alkoxy or a halogen atom; R<3> represents hydrogen, lower alkyl, lower alkoxy, or phenylalkyloxy which may be substituted by halogen or lower alkyl; R<4> represents hydrogen, lower alkyl or lower alkoxy; R<5> represents hydrogen or lower alkyl; and n represents an integer of 1 to 5Ü. This compound has the effects of both blocking alpha 1-adrenergic receptors and inhibiting testosterone 5 alpha -reductases, and is useful as a remedy and/or a preventive for diseases caused by dihydrotestosterone overproduction, such as prostatic hypertrophy, and diseases accompanying the same, such as urination disorder, male pattern alopecia, acne, and so forth.
Patent UY-28637-A1 (UY)
Title: Máquina para el suministro de un alimento caliente incluido en una masa
Inventor: RUBEN CAMPOS CARLOS
IPC: A23L5/10
Filed: 2004-11-26
Abstract: Máquina: constituida por dos partes, una superior compuestos por tapa que contienen moldes y una fuente de suministro calórico, una inferior compuesta por moldes y una fuente de suministro calórico, articuladas por bisagra. La tapa superior tiene un perfil que incluye salientes correspondientes a cada compartimiento de la plancha de moldeo, que penetrarán el alimento. Los moldes superiores e inferiores, poseen compartimientos que van a alojar la masa y que posee orificios de descarga para eliminar excedentes alimenticios. El método de uso: verter sobre el molde, pasta, colocar sobre ella, un producto alimenticio variado, cerrar tapa, aplicar calor. El producto alimenticio quedará envuelto en una masa.
Patent UY-30652-A1 (UY)
Title: N-(2-hidroxietil)-n-metil-4-(quinolin-8-il(1-(tiazol-4-ilmetil)piperidin-4-ilideno)metil)benzamida
Inventor: YAN JINGBO
IPC: A61P25/00
Filed: 2007-10-19
Abstract: N-(2-hidroxietil)-N-metil-4-(quinolin-8-il(1-(tiazol-4-ilmetil)piperidin-4-ilideno)metil)benzamida, sales farmacéuticamente aceptables de la misma y/o mezclas de la misma, al igual que composiciones famacéuticas de la misma, métodos de tratamiento que las emplea y procesos para preparar N-(2-hidroxietil)-N-metil-4-(quinolin-8-il(1-(tiazol-4ilmetil)piperidin-4-ilideno)metil)benzamida intermediarios de la misma.
Patent ES-149946-A1 (ES)
Title: PERFECCIONAMIENTOS EN LOS HORNOS ELÉCTRICOS DESTINADOS PARTICULARMENTE A LA FUSIoN DEL VIDRIO O DE MATERIALES ViTREOS
Filed: 1940-07-15
Abstract: Horno eléctrico destinado particularmente a la fusión de vidrio o de materiales vítreosdel tipo según el cual el caldeo del material se obtiene por paso d euna corriente por el mismo materialpor medio de electrodos que se extienden cada uno de un borde al otro del hornocaracterizado por al menos un electrodo constituido por elementos colocados a tope de manera que constituyen un electrodo prácticamente continuo que se extiende de una pared a otra del hornopero cada uno de los elementos puede con relación al plano medio longitudinal del horno o con relación a las paredes de éste últimotener una orientación requerida cualquiera independiente de la de los otros elementos.
Patent ES-153346-A1 (ES)
Title: PROCEDIMIENTO PARA OBTENER NITROSULFOCLORUROS AROMáTICOS, TENIENDO EL RADICAL SO2CL EN POSICIoN PARA RESPECTO AL GRUPO NO2
Filed: 1941-06-21
Abstract: Proedimiento de preparación de nitro-sulfocloruros aromáticos teniendo el grupo nitro en posición para respecto al radical sulfoclorurocaracterizado en que se tratan los para-cloro-nitro-derivados aromáticos (o los para halógeno-nitro-derivados aromáticosen general) con disulfuros o polisulfuros alcalinos o alcalino-térreosobteniendo dinitro-disulfuros o dinitro-polisulfuros aromáticosque son tratados con agentes oxidantes y halogenantes para transformarlos en los para-nitro-sulfo-halógeno-derivados aromáticos equivalentes.
Patent ES-182177-A1 (ES)
Title: UN SISTEMA DE GENERACIoN DE IMPULSOS
IPC: H03K4/10
Filed: 1948-02-07
Abstract: Sistema para producir un impulso estrecho comprendiendo la producción de un impulso de entrada de forma rectangular, un impulso formado, y más tarde uno de cuyos bordes está curvado, mezclando la energía de este impulso formado con la energía del impulso de entrada de polaridad opuesta para producir una porción de impulso uno de cuyos bordes es substancialmente vertical de acuerdo con una de las porciones del borde del impulso de entrada y el otro borde opuesto está curvado de acuerdo con dicho borde curvado, dicha porción de borde vertical contigua a dicha porción curvada.
Patent ES-196021-A1 (ES)
Title: UN DISPOSITIVO DE MANDO AUTOMáTICO DE LOS APARATOS DE REGULADO PARA INSTALACIONES DE CALEFACCIoN MEDIANTE VAPOR
Filed: 1951-01-04
Abstract: Dispositivo de mando de los aparatos de regulación para instalación o instalaciones de calefacción mediante vapor caracterizado por el hecho de que el cierre del interruptor del circuito eléctrico alimentando los aparatos de regulado es accionado por un pistón descansando sobre una cara de un diafragma en la que la otra cara está expuesta a la acción del vapor apretándose el pistón hacia su posición de descanso por un resorte proporcionando de manera a impedir el levantado del diafragma con respecto a su asiento mientras que no haya alcanzado la presión del vapor un valor determinado
Patent ES-197812-A1 (ES)
Title: Un cierre basculante para ventanas, puertas, paredes divisorias y similares
Filed: 1951-05-09
Abstract: Un cierre basculante para ventanas puertas paredes divisorias o similares caracterizado porque comprende un bastidor fijo y un bastidor móvil y medios para permitir la rotación relativa de los dos bastidores según un eje situado al exterior del cierre y paralelo al plano de este cierre de modo que se permita realizar en correspondencia con la inversión de las ranuras estancas de los dos bastidores a lo largo de los lados provistos de pivotes de unión un encaje normal de ranuras longitudinales y paralelo al eje de oscilación tanto que se asegure la continuidad de la estanqueidad sobre el perímetro total de los bastidores.
Patent ES-197984-A1 (ES)
Title: UNA INSTALACIoN SIMPLIFICADA DE BLOCK DE ViA DE FERROCARRIL
Filed: 1951-05-22
Abstract: Instalación de block de vía de ferrocarril caracterizada porque por medio del circuito de petición de vía libre estando la vía desbloqueada el bloqueo de la vía y la determinación del sentido de la marcha para una salida es iniciado por la estación peticionaria realizándose la intercalación del relé de emisión y el de recepción en el bucle de unión para el mando de los impulsos de block por una cadena de relés dispuesta en ambas estaciones.
Patent ES-293142-A1 (ES)
Title: Process for the production of acetic anhydride
IPC: C07C51/54
Filed: 1963-11-04
Abstract: In a process for the preparation of acetic anhydride by the catalytic oxidation of acetaldehyde the products, entrained in excess of the oxygen-containing gas, are fractionally distilled and at least part of the by-products with a B.P. above that of acetic anhydride are returned to the oxidation bath to bring the high-boiling by-products (with B.P's of 77-78 DEG C. and above at 30 mm. Hg pressure) in the bath to at least 45% by weight of the bath. Fractional distillation of the by-products yields an ethylidene diacetate fraction (40%), a fraction (B.P. 80-120 DEG C.) (30-40%) and a viscous, coloured residual fraction of high specific weight. The latter fraction is preferably excluded from the recirculation. Specifications 653,942 and 910,861 are referred to.
Patent ES-299901-A1 (ES)
Title: Manufacture of flat glass on improved molten metal bath
IPC: C03B18/18
Filed: 1964-05-16
Abstract: The bed of molten metal on which a ribbon of glass is supported during manufacture is constituted by an alloy of tin with one of the noble metals silver, gold, platinum, palladium, or rhodium or an alloy of two or more of them. Preferably the alloying metal is silver and it is used in the proportion of 1-50% to produce an alloy having a melting-point below 700 DEG C.ALSO:In the production of flat glass in ribbon form as disclosed in Specifications 893,663 and 769,692, the support bed is constituted by an alloy of tin with one of the noble metals silver, gold, platinum, palladium, or rhodium or an alloy of two or more of them. Preferably, the alloying metal is silver and it is used in the preparation of 1-50% to produce an alloy having a melting-point below 700 DEG C.
Patent ES-331474-A1 (ES)
Title: Device for the positive protection of a thermionic tube
IPC: H03F1/54
Filed: 1966-09-22
Abstract: In a circuit of the type in which a pulse from a store is applied to an output valve, e.g. a klystron, by triggering a switching valve, the output valve is protected against circuit faults by shunting the store with a discharge device, and applying to the trigger electrode of this device two antiphase pulses which normally cancel out to prevent the device from being triggered. One pulse is derived from the pulse which triggers the switching valve, and the other is derived from the output of the store, so that failure of either one will cause the device to trigger and discharge the store. As described, the store comprises a number of parallel connected capacitors 41, 411, 4111 which may be discharged by triggering parallel connected valves 80, 82 to feed a pulse to line 2 via transformer 6. The triggering circuit 18 for the valves 80, 82 include a pulse shaping network 90, 92, 94 and in order to maintain the pulse amplitude constant feedback is applied via amplifier 96 from transformer 6. Capacitors 4 are shunted by a spark-gap 52, 54 whose trigger electrode is fed with the input trigger pulse via amplifier 32 and transformer 30 and also with the output of transformer 6 obtained from secondary winding 86. The output line is provided with a limiting circuit 48, 50. The sparkgap 52, 54 may be replaced by an ignition or thyratron.
Patent ES-331819-A1 (ES)
Title: Pressurizer
IPC: G21C1/09
Filed: 1968-09-30
Abstract: A pressurized water primary circuit of a power generating installation (not shown) is provided with a closed expansion vessel 1. When the power demanded from the installation decreases, the resultant increase in temperature of the water in the primary circuit causes it to expand along conduit 2 and enter the vessel 1 which contains steam and water phases maintained in equilibrium at a higher temperature than that of the water in the primary circuit, by controlled heat source 7. To obviate the pressure increase in the vessel 1 which would otherwise occur when the expansion water from conduit 2 enters it, part at least of this cooler water is passed through a heat exchanger 6 in the steam phase before being discharged into the vessel through orifice C, so cooling and condensing some of the steam. When the power demanded from the installation increases and the water in the primary circuit contracts, water passes from the vessel 1 to the primary circuit through orifice B, and non return valve 4. The resultant pressure drop of the steam in the vessel 1, is partly offset by evaporation of some of the hot water remaining in vessel 1, so reducing the pressure variation.
Patent ES-334953-A1 (ES)
Title: A process for the preparation of 3-nitro-4-halophenol derivatives
IPC: C07C205/60
Filed: 1966-12-09
Abstract: The invention comprises compounds of the general formula <FORM:1100219/C2/1> in which R is alkoxycarbonyl or alkyl and X is halogen. The new compounds are produced by reacting compounds of the general formula <FORM:1100219/C2/2> with nitrous acid or metallic nitrites in the presence of an acid and treating the resulting diazonium salts with water to yield the 3-nitro-4-halophenol derivatives. An example is given of the preparation of 2-methyl-4-chloro-5-nitrophenol.
Patent ES-345038-A1 (ES)
Title: Propylene Polymer Moldings and their production
IPC: C08L23/10
Filed: 1967-09-14
Abstract: Homopolymers of propylene and copolymers of propylene with one or more other olefins and which contain at least 90% of propylene units, and which are made by a gas-phase polymerization process and which contain at least 15% by weight of polymeric material soluble in boiling n-heptane under standard pressure, and less than 100 p.p.m. of ash constituents are moulded into articles. The polymer may be moulded per se or mixed with pigments, stabilizers, ageing retardants, fillers, or other polymers such as polyethylene or vinyl chloride. The polymerization is preferably effected in the presence of a catalyst comprising TiCl 3 .1/3 AlCl 3 and which yields at least 10,000 parts by weight of polymer per part of TiCl 3 . 1/3 AlCl 3 . The polymers and compositions thereof may be moulded by known techniques into filaments, threads, fibres, tapes, ribbons, films, and sheets, and these may be monoaxially or bi-axially stretched after formation.
Patent ES-348421-A1 (ES)
Title: Trigger mechanism for automatic firearms
IPC: F41A19/46
Filed: 1967-12-19
Abstract: A trigger mechanism for an automatic firearm disposed in a trigger box 1 and having a lever 21 for catching and holding the breech block (not shown) in a rearmost position and a trigger 10 having an associated part 29 for displacing the catch lever from its position where it projects into the path of the breech block, is characterized by the provision, on the same pivot 9 as the trigger 10, of a plate 31 which is rotatable relatively to the trigger and is provided with two sectors 32, 33 of different radii separated by a steep flank, the catch lever 21 having a hook shaped lug 25 which engages the larger radius sector 32 when the trigger is pulled and which drops on to the smaller radius sector 33 when the trigger is released. The plate is biased by a spring 34 to rotate clockwise as shown in the Figure, where the trigger is in the released position. When the trigger 10 is pulled, lug 29 engages lever 21 and rotates it to withdraw its end 23 from the breech block, the hook 25 moving away from plate 31 which is then rotated by its spring to place sector 32 behind the hook to prevent the lever moving back into a block engaging position. When the trigger is released its pin and slot connection 35, 36 with the plate delays the return movement of the latter until near the end of the trigger release movement when the plate rotates allowing the hook to snap on to sector 33 and present its end 23 to engage the block. The device is shown in a firing mechanism having a hammer 2 provided with bents 8, 18 engaging respectively a trigger sear 7 and a part 17 which is withdrawn from its bent by the action of a lever 19 operated by the forward movement of the breech block. The hammer 2 is provided with a device 41 pivoted thereto which moves the hammer further, when the device is contacted by the breech block on hand cocking, than would otherwise be the case. In automatic firing this further movement is achieved by the inertia of the hammer, the bent 8 and sear 7 being arranged to reengage only after this further movement, to prevent hammer being caught by trigger lever 6 when the trigger is released with the breech advancing. This prevents a cartridge being introduced into a heated barrel without being fired.
Patent ES-349278-A1 (ES)
Title: Oil burner with rotating distributor head
IPC: F23D11/08
Filed: 1968-01-13
Abstract: An oil burner comprises a rotatable inverted conical distributer head 11 driven by a motor 9 and supplied with fuel from a reservoir 17 up a tube 10 to the inner surface thereof, the oil being thrown off either edges 23 of slits 15 or off top edge 14, there being attached to the outer surface of the cone blades 13 projecting above edge 14, which blades draw air up through aperture 20 and serve to mix it with the fuel, and there being further provided an apertured cylinder 21 above the head 11 which recirculates combustion gases 26. The burner is located in a boiler 1 partially closed at its lower end by a frusto-conical base 6 defining aperture 20. An igniter 8 is provided. In modifications the blades can either be formed by cut-outs from the top part of the head bent out of the surface of the cone, or by cut-outs from a horizontal flange attached to edge 14. In a further modification an annular blade system.is attached by a few supports to the top edge of the cone.
Patent ES-351226-A1 (ES)
Title: Pneumatic fastener inserting machines
IPC: A43D100/02
Filed: 1968-02-24
Abstract: An eyeletting machine comprises a pair of opposed dies 54, 166 with a pneumatic piston cylinder assembly 44, 46 to move them together and the lower die is mounted on a support 130 which is indexed pneumatically to pick up eyelets from a shoot 260 and convey them to the setting position. The support 130 has a bore 136 supplied with compressed air and an exhaust bore 138. The bores are alternatively communicated with each of a series of bores 190 with balls 210 which are forced apart by the air on to cams (214), Fig. 6 (not shown), to continuously urge the support to rotate. The support 130 has spaced segments (165), Fig. 8 (not shown), which are held by a stop (230) which is retracted manually by a lever (254), Fig. 9 (not shown). A second stop (228) prevents over-run of the support. The lever is weighted to bias the stop (230) into its engaging position. A leaf spring (256) with a projection (258) prevents reverse rotation of the support. The ram 51 is supplied with air from a duct 62 via a valve housing 64 which has an inlet 70 from a compressed air source and an outlet 96 to bleed the housing. A valve spool (68), Fig. 3 (not shown), in the housing is spring biased so that normally the inlet 70 and outlet 96 are interconnected to bleed of the air. When the bleed opening is closed by the operator's finger, the pressure builds up, causes the spool to move and interconnect the inlet 70 with the duct 62. The spring biasing is provided by three balls (100), (102), (104), two of which are urged together and the third urged between them by the spool. A screw (114), Fig. 4 (not shown), limits the movement of the ball (100) and hence the spool. The ram is returned under spring 60 bias when one of the spool pistons passes an exhaust port (76). The eyelets are fed from a vibrating hopper 380 (see Division B8) down a shoot 260. The foot of the shoot has a leaf-spring retainer 272 and a cover-plate 280 so that only the lowest eyelet 1 is exposed. The die pins of the lower dies are urged outwards by air inside the support 130 and as the support rotates the pins are moved rearward by the plate 280 and then spring outwards into the eyelet. Further rotation of the support deflects the leaf spring 272 and the eyelets are retained on the pins by a curved plate 282, until the pin is almost vertical. The position of both the upper and lower dies in the eyeletting position is adjustable by bolts 32 and by altering the position of the support stop (230). In operation the eyelets are poured randomly into the hopper and the lever (254) is depressed to move the stop (230) from the segment (165) to allow the support to rotate and pick up the lowermost eyelet. The lever is depressed again so that the next die pin picks up the next eyelet 1 and the first eyelet is conveyed to the setting position. The bleed opening of the outlet 96 is closed and the ram descends to set the eyelet.