baber/WOPTO huggingface dataset:
Patent CY-1112113-T1 (CY)
Title: Συνδυασμος ενος αλατος του δις-θειαζολιου ή μιας προδρομης ενωσης του και αρτεμισινινης ή ενος παραγωγου της για τη θεραπευτικη αντιμετωπιση της βαριας ελονοσιας
Inventor: FRAISSE LAURENT
IPC: A61K31/357
Filed: 2011-11-24
Abstract: Η εφεύρεση έχει ως αντικείμενο ένα συνδυασμό, ο οποίος περιέχει ένα άλας του δις-θειαζολίου ένωση με τον τύπο (VI) ή μία πρόδρομη ένωση του και της αρτεμισινίνης ή ενός παραγώγου της. Η εφεύρεση έχει επίσης ως αντικείμενο μία φαρμακευτική σύνθεση η οποία περιέχει τουλάχιστον ένα άλας του δις-θειαζολίου, ένωση με τον τύπο (VI) ή μία πρόδρομη ένωση του και αρτεμισινίνη ή ένα παράγωγό της. Η εφεύρεση έχει επίσης ως αντικείμενο έναν τέτοιο συνδυασμό, για την παρασκευή ενός φαρμάκου το οποίο προορίζεται για τη θεραπευτική αντιμετώπιση ή/και την πρόληψη της βαριάς ελονοσίας. Η εφεύρεση έχει τέλος ως αντικείμενο μία συσκευασία για τη θεραπευτική αντιμετώπιση ή/και την πρόληψη της βαριάς ελονοσίας.
Patent CY-1117345-T1 (CY)
Title: Μεθοδος για τη δημιουργια ενος κλειδιου κρυπτογραφησης/αποκρυπτογραφησης
Inventor: REVELL ELISE
IPC: H04L9/08
Filed: 2016-03-17
Abstract: Η παρούσα εφεύρεση σχετίζεται με μια μέθοδο για τη δημιουργία ενός κλειδιού κρυπτογράφησης/ αποκρυπτογράφησης, και ειδικά για τη δημιουργία κλειδιού κρυπτογράφησης/αποκρυπτογράφησης μοναδικής φοράς που χρησιμοποιείται για συμμετρική κρυπτογράφηση, δηλαδή όπου το ίδιο κλειδί χρησιμοποιείται για την κρυπτογράφηση και για την αποκρυπτογράφηση. Προκειμένου να γίνει η δημιουργία του κλειδιού ένας πρώτος κόμβος (Α) στέλνει ένα αίτημα σε έναν κεντρικό εξυπηρετητή (2) για τη σύσταση επικοινωνίας με ένα δεύτερο κόμβο (Β). Ο κεντρικός εξυπηρετητής (2) στέλνει ένα φάκελο δημιουργίας κλειδιού και στους δύο κόμβους (Α και Β). Κάθε κόμβος δημιουργεί ένα διαφορετικό ενδιάμεσο σύνολο δεδομένων, δηλαδή ένα πρώτο και ένα δεύτερο σύνολο δεδομένων. Το πρώτο σύνολο δεδομένων δημιουργείται από τον πρώτο κόμβο (Α) αποστέλλεται στο δεύτερο κόμβο (Β), που βασιζόμενο σε αυτά τα δεδομένα δημιουργεί ένα τρίτο σύνολο δεδομένων που στέλνεται πίσω στον πρώτο κόμβο. Η δημιουργία ενός πρώτου κρυπτογραφικού κλειδιού σε ένα κόμβο (Α) βασίζεται στη σύγκριση του κάθε δυαδικού ψηφίου μεταξύ του τρίτου και του πρώτου ενδιάμεσου συνόλου δεδομένων και η δημιουργία ενός δεύτερου κρυπτογραφικού κλειδιού βασίζεται στη σύγκριση του κάθε δυαδικού ψηφίου μεταξύ του πρώτου και του δεύτερου ενδιάμεσου συνόλου δεδομένων. Το πρώτο και το δεύτερο κρυπτογραφικό κλειδί είναι το ίδιο.
Patent CY-1119059-T1 (CY)
Title: Χρηση προφαρμακων κανναβιδιολης σε τοπικη και διαδερμικη χορηγηση με μικροβελονες
Inventor: STINCHCOMB AUDRA LYNN
IPC: C07C271/52
Filed: 2017-06-23
Abstract: Εδώ περιγράφονται συστήματα χορήγησης φαρμάκου με μικροβελόνες, τα οποία περιέχουν μία φαρμακευτική σύνθεση που περιλαμβάνει φαρμακευτικά δραστικούς παράγοντες (π.χ. κανναβιδιόλη και προφάρμακα κανναβιδιόλης) και διατάξεις μικροβελόνων που είναι κατάλληλες για τοπική και συστημική χορήγηση του δραστικού παράγοντα σε ένα θηλαστικό. Επίσης εδώ περιγράφονται μέθοδοι για τη χρήση ενός συστήματος διαδερμικής ή τοπικής χορήγησης φαρμάκου με μικροβελόνες που περιλαμβάνει φαρμακευτικές συνθέσεις, οι οποίες περιλαμβάνουν κανναβιδιόλη και προφάρμακα κανναβιδιόλης, και διατάξεις μικροβελόνων στη θεραπεία ασθένειας, συμπεριλαμβανομένων της παγκρεατίτιδας και του καρκίνου του παγκρέατος.
Patent CY-1122523-T1 (CY)
Title: Πεπτιδια και πεπτιδομιμητικα σε συνδυαστικες χρησεις και αγωγες για υποπληθυσμους πασχοντων απο καρκινο
Inventor: KAWABE TAKUMI
IPC: A61P35/00
Filed: 2019-12-23
Abstract: Η παρούσα εφεύρεση παρέχει ενώσεις που συμπεριλαμβάνουν πεπτίδια και πεπτιδομιμητικά που μπορούν να χρησιμοποιηθούν για την αγωγή διαταραχών του κυτταρικού πολλαπλασιασμού όπως αυτές οι οποίες συνδέονται με καλοήθη και κακοήθη κύτταρα όγκου. Ενώ η εφεύρεση δεν περιορίζεται σε οποιονδήποτε συγκεκριμένο μηχανισμό, οι ενώσεις της εφεύρεσης εμφανίζονται να λειτουργούν, τουλάχιστον εν μέρει, δια αναστολής του σημείου ελέγχου του κυτταρικού κύκλου G2. Έτσι, οι ενώσεις της εφεύρεσης μπορούν να χρησιμοποιηθούν για την αναστολή της κυτταρικής αύξησης μόνον ή να χρησιμοποιηθούν σε συνδυασμό με μία αγωγή βλάβης νουκλεϊκού οξέος ώστε να ανασταλεί η κυτταρική αύξηση.
Patent CY-1124655-T1 (CY)
Title: Κρυσταλλικες μορφες και μορφες αλατος ενωσεων οι οποιες ειναι αγωνιστες του ppar
Inventor: LAGU BHARAT
IPC: C07D233/64
Filed: 2021-08-31
Abstract: Η παρούσα κοινολόγηση αναφέρεται σε μορφές άλατος ενώσεων οι οποίες έχουν τη δυνατότητα να ενεργοποιούν τον PPARδ για χρήση στην ανάπτυξη φαρμακευτικών ουσιών και φαρμακευτικών προϊόντων, και σε σχετικές συνθέσεις και μεθόδους.
Patent CY-1124574-T1 (CY)
Title: Προφαρμακο παραγωγου αμινοξεος
Inventor: OTAKE NORIKAZU
IPC: C07C229/50
Filed: 2021-10-08
Abstract: Παρέχεται ένα προφάρμακο παραγώγου αμινοξέος που αντιπροσωπεύεται από τον γενικό τύπο ένωσης (ΙΑ) που είναι μια μορφή προφαρμάκου ενός παραγώγου αμινοξέος που είναι ένας ανταγωνιστής μεταβολτροπικού υποδοχέα γλουταμικού ομάδας 2, ή ένα φαρμακευτικά αποδεκτό άλας αυτού. Πιο συγκεκριμένα, παρέχεται ένα προφάρμακο αμινοξέων που αντιπροσωπεύεται από τον γενικό τύπο ένωσης (Ι-Α) που είναι προληπτικό ή θεραπευτικό φάρμακο για διαταραχές της διάθεσης (συμπεριλαμβανομένης της κατάθλιψης και της διπολικής διαταραχής), της αγχώδους διαταραχής, των γνωστικών διαταραχών, των αναπτυξιακών διαταραχών, της νόσου Αλτσχάιμερ, της νόσου του Πάρκινσον, των κινητικών διαταραχών που σχετίζονται με μυϊκή ακαμψία, των διαταραχών ύπνου, της χορείας του Huntington, των διατροφικών διαταραχών, της εξάρτησης από τα ναρκωτικά, της επιληψίας, του εμφράγματος του εγκεφάλου, της εγκεφαλικής ισχαιμίας, της εγκεφαλικής ανεπάρκειας, του εγκεφαλικού οιδήματος, των διαταραχών του νωτιαίου μυελού, του τραύματος στο κεφάλι, της φλεγμονής και των ασθενειών που σχετίζονται με το ανοσοποιητικό και ούτω καθ' εξής.
Patent HR-P20100039-T1 (HR)
Inventor: COSTANTINI DOMINIQUE
IPC: A61K31/522
Filed: 2010-01-21
Abstract: Postupak za pripremu nosača bioadhezivnog za sluznicu sa sporim oslobađanjem, naznačen time što sadrži: a)	miješanje najmanje jednog aktivnog elementa sa alkilsulfatom alkalnog metala i razblaživačem; b)	vlaženje navedene smjese vezivnim sredstvom; c)	sušenje i ujednačavanje navedene smjese; d)	granulacija navedene smjese tako da se formiraju primarne granule; e)	miješanje navedenih primarnih granula sa najmanje jednim bioadhezivnim polimerom i najmanje jednim polimerom za produženo oslobađanje i najmanje jednim sredstvom za prešanje; if)	prešanje navedene smjese u e). Patent sadrži još 18 patentnih zahtjeva.
Patent HR-P20110320-T1 (HR)
Title: Binding molecules capable of neutralizing rabies virus and uses thereof
Inventor: BAKKER ALEXANDER BERTHOLD HENDRIK
IPC: G01N33/569
Filed: 2011-05-03
Abstract: The present invention provides binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. The invention further provides nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. Preferably, they can be used in the postexposure prophylaxis of rabies.
Patent HR-P20110903-T1 (HR)
Inventor: RODGERS JAMES D
IPC: C07D471/04
Filed: 2011-12-01
Abstract: Spoj formule I: ili njegova farmaceutski prihvatljiva sol, naznačen time da: T, U, i V su nezavisno odabrani od O, S, N, CR5, i NR6;pri čemu 5-člani prsten koji formira atom ugljika, atom dušika, U, T, i V je aromatski; X je N ili CR4;n je 0; ilin je I i Y je C1-8alkilen, C2-8alkenilen, (CR11R12)pC(O)(CR11R12)q, (CR11R12)pC(O)NRc(CR11R12)q, (CR11R12)pC(O)O(CR11R12)q, ili (CR11R12)pOC(O)(CR11R12)q, pri čemu navedeni C1-8alkilen ili C2-8alkenilen, je proizvoljno supstituiran sa 1, 2, ili 3 halo, OH, CN, amino, C1-4alkilamino, ili C2-8dialkilamino; Z je aril, cikloalkil, heteroaril, ili heterocikloalkil, svaki proizvoljno supstituiran sa 1, 2, 3, 4, 5, ili 6 nezavisnih supstituenata odabranih od halo, C1-4 alkila, C2-4 alkenila, C2-4 alkinila, C1-4 haloalkila, C1-4 hidroksialkila, C1-4 cijanoalkila, Cy1, CN, NO2, ORa, SRa, C(O)Rb, C(O)NRcRd, C(O)ORa, OC(O)Rb, OC(O)NRcRd, NRcRd, NRcC(O)Rb, NRcC(O)NRcRd, NRcC(O)ORa, S(O)Rb, S(O)NRcRd, S(O)2Rb, NRcS(O)2Rb, i S(O)2NRcRd;Cy1 je nezavisno odabran od arila, heteroarila, cikloalkila, i heterocikloalkila, svaki proizvoljno supstituiran sa 1, 2, 3, 4 ili 5 supstituenata nezavisno odabranih od halo, C1-4 alkila, C2-4 alkenila, C2-4 alkinila, C1-4 haloalkila, CN, NO2, ORa, SRa, C(O)Rb , C(O)NRcRd", C(O)ORa", OC(O)Rb", OC(O)NRc"Rd", NRc" Rd", NRc"C(O)Rb", NRc"C(O)ORa" S(O)Rb", S(O)NRcRd", S(O)2Rb", i S(O)2NRc"Rd";R4 je H; R5 je H, halo, C1-4alkil, C2-4alkenil, C2-4alkinil, C1-4haloalkil, CN, NO2, OR7, SR7, C(O)R8, C(O)NR9R10, C(O)OR7,OC(O)R8, OC(O)NR9R10, NR9R10, NR9C(O)R8, NR9C(O)OR7, S(O)R8, S(O)NR9R10 S(O)2R8, NR9S(O)2R8 ili S(O)2NRR10;R6 je H, C1-4alkil, C2-4alkenil, C2-4alkinil, C1-4haloalkil, OR7, C(O)R8, C(O)NR9R10, C(O)OR7, S(O)R8, S(O)NR9R10, S(O)2R8, ili S(O)2NR9R10;R7 je H, C1-6alkil, C1-6haloalkil, C2-6alkenil, C2-6alkinil, aril, cikloalkil, heteroaril, heterocikloalkil, arilalkil, heteroarilalkil, cikloalkilalkil ili heterocikloalkilalkil; R8 je H, C1-6alkil, C1-6haloalkil, C2-6alkenil, C2-6alkinil, aril, cikloalkil, heteroaril, heterocikloalkil, arilalkil, heteroarilalkil, cikloalkilalkil ili heterocikloalkilalkil; R9 i R10 su nezavisno odabrani od H, C1-10alkila, C1-6haloalkila, C2-6alkenila, C2-6alkinila,
Patent SI-1187691-T1 (SI)
Title: Method for continuously casting ferritic stainless steel strips free of microcracks
Inventor: MAZURIER FREDERIC
IPC: B22D11/117
Filed: 2000-03-29
Abstract: The invention concerns a method for continuously casting a ferritic stainless steep strip with thickness not more than 10 mm directly from liquid metal between two cooled rolls with horizontal axes and driven in rotation, characterized in that: the liquid metal composition in weight percentages is as follows: % C+% N<=0.12; % Mn<=1; % P<=0.4; % Si<=1; % Mo<=2.5; % Cr between 11 and 19; A1<=1%; % Ti+%Nb+% Zr<=1; the rest being iron and the impurities resulting from preparation; the Upsilp index of the liquid metal ranges between 35% and 60%, Upsilp being defined by the formula: gammap=420% C+470% N+23% Ni+9% Cu+7% Mn 11.5% Cr 11.5% Si 12% Mo 23% V 47% Nb 49% Ti 52% A1+189: the surface roughness of said rolls being more than 5 mum; in the proximity of the meniscus metal liquid present between the rolls an inerting gas is used consisting of at least 60% by volume of a gas soluble in steel.
Patent SI-1081641-T1 (SI)
Title: Electromechanical counter mechanism
Inventor: BANHOLZER KURT
IPC: G01R11/16
Filed: 2000-07-29
Abstract: The electromechanical counter (1) has a series of decimal numbered discs (34) that are geared together to provide a multiple digit count value. The drive mechanism consists of a stepping motor with a screened housing (25) that is latched (12,13) to the main housing. The motor has a worm and pinion (29) coupling to the gear input (33) of the discs.
Patent SI-1581474-T1 (SI)
Title: Chiral arylketones in the treatement of neutrophil-dependent inflammatory deseases
Inventor: ALLEGRETTI MARCELLO
IPC: A61K31/00
Filed: 2003-12-09
Abstract: The compounds of formula (I): where Ar is an aromatic ring and Ra, Rb, are as defined in the description, are useful in therapy as drugs for the treatment of diseases mediated by infiltrations of neutrophils induced by IL-8, such as psoriasis, rheumatoid arthritis, ulcerative cholitis and for the treatment of damages caused by ischemia and reperfusion.
Patent SI-1636389-T1 (SI)
Title: Plasmid-free clone of e. coli strain dsm 6601
Inventor: HACKER JORG
IPC: C12N1/00
Filed: 2004-06-25
Abstract: The invention relates to a plasmid-free clone of Escherichia coli strain DSM 6601, to a method for preparing the same and to the use thereof as a cloning vehicle.
Patent SI-1772741-T1 (SI)
Title: Solid sample nuclear magnetic resonance measuring method
Inventor: MIURA IWAO
IPC: G01R33/44
Filed: 2005-07-27
Abstract: In a nuclear magnetic resonance measuring method for solid samples, there are provided the steps of exciting a nuclear spin of a solid sample placed in a static magnetic field by allowing exciting pulses to pass through a receiver coil. A FID signal (Free Induction Decay signal) is received from the excited nuclear spin by applying reading pulses after a lapse of time Ä after applying the exciting pulses is finished. An Inversion Recovery IR - Nuclear Magnetic Resonance NMR spectrum is obtained by subjecting the FID signal to a frequency conversion process. The estimation of a constituent ratio of constituent substances of the solid sample is achieved by acquiring a plurality of FID signals while changing the period of time Ä, by calculating IR-NMR spectra based on these FID signals, by obtaining a longitudinal relaxation curve by plotting spectrum strength with respect to time Ä in a specific frequency of the TR-NMR spectrum, and by making a regression analysis while regarding the longitudinal relaxation curve as a total sum of a plurality of longitudinal relaxation curves differing in longitudinal relaxation time.
Patent SI-1841510-T1 (SI)
Title: Kit for a counter current swimming pool
Inventor: HOF GEORG
IPC: A63B69/12
Filed: 2006-01-17
Abstract: The invention relates to a kit for a counter-current swimming pool, wherein water is pumped inwards on a defining wall of a swimming pool (1) along the entire horizontal extension thereof and is discharged on the opposite boundary wall along the entire horizontal extension thereof. In order to enable retrofitting of the kit into existing swimming pools, an insert (2, 3) is formed or incorporated into the swimming pool (1), comprising a cover plate (4, 5) which defines the swimming area below and from which boundary walls (6, 8) emanate. The boundary walls extend in a parallel or substantially parallel manner as far as the bottom of the swimming pool, wherein, in the region between the boundary walls (6, 8), axial propelling means, i.e. propellers (10) are provided together with a drive device and wherein the cover plates (4, 5), when seen in the direction of flow, terminate both on the front end (14) and rear end (15) with the formation of a gap (16, 17), which is used to pump in or to discharge water, at a distance from the adjacent wall of the swimming pool.
Patent SI-1747995-T1 (SI)
Title: Method and apparatus for the gastight conditioning of articles in a skin-packaging foil
Inventor: VON SEGGERN JORG
IPC: B65B31/02
Filed: 2006-07-13
Abstract: A dish (6) with a peripheral edge (10) creates packaging. Swaged foil (4) is cut to the size of the peripheral edge. Subsequently and/or at the same time, the swaged foil is applied to the peripheral edge so as to be gas-proof. The swaged is welded onto the peripheral edge of the dish with a vacuum in the surrounding area of the dish. Independent claims are also included for the following: (1) A device for gas-proof packaging of objects; (2) Packaging for an object with a dish and a swaged foil for putting onto the dish.
Patent SI-1748003-T1 (SI)
Title: Process and device for testing garbage for metallic elements
Inventor: MAIER HANS JURGEN
IPC: B65F3/00
Filed: 2006-05-09
Abstract: The refuse searching process involves searching the refuse in a refuse container for metal waste. At least one metal probe (8, 9) is used for this purpose, moving it along the refuse container from below while the refuse container is raised by a lifting device (3, 4) on the dustcart (1), continuously or in stages, from bottom to top.
Patent SI-1869085-T1 (SI)
Title: Novel anti-plgf antibody
Inventor: STASSEN JEAN-MARIE
IPC: A61K39/00
Filed: 2006-03-24
Abstract: The present invention provides novel monoclonal antibodies directed to PIGF and fragments and derivatives thereof, more particularly to humanized antibodies and fragments thereof for use in the treatment and/or prevention of pathological angiogenesis.
Patent SI-2125794-T1 (SI)
Title: Imidazolidinonyl aminopyrimidine compounds for the treatment of cancer
Inventor: LI HONG-YU
IPC: A61K31/381
Filed: 2007-12-11
Abstract: The present invention provides novel imidazolidinonyl aminopyrimidine compounds believed to have clinical use for treatment of cancer through inhibiting Plk1. Formula I wherein: R1 is aminomethyl, (C1-C3 alkyl)aminomethyl, di(C1-C2 alkyl)aminomethyl, N-ethyl-N-methyl-aminomethyl, 1-aminoethyl, 1-((C1-C2 alkyl)amino)-ethyl, 3,3,3-trifluoro-propylaminomethyl, ethynyl, 2-hydroxy-ethoxy, 2-hydroxyethylaminomethyl, 2-cyanoethylaminomethyl, mopholin-4-ylmethyl, methoxymethoxymethyl, cyclopropyl, 1-azetidinylmethyl, 1-pyrrolidinylmethyl, or 1,3-dioxolan-2-yl; R2 is hydrogen or halo; R3 is hydrogen or halo; provided that at least one of R2 and R3 is hydrogen; R4 is hydrogen, methyl, or halo; and is a single bond that is either present or absent, or a pharmaceutically acceptable salt thereof.
Patent SI-2134311-T1 (SI)
Title: Multidose vial assemblies and adapters therefor
Inventor: WEITZEL DIETMAR
IPC: A61J1/14
Filed: 2008-03-26
Abstract: A multidose vial assembly which comprises a multidose vial (10), a withdrawal spike (30), and an adapter (60) that couples the multidose vial and the withdrawal spike together in a safe and secure manner.
Patent TR-201113186-T1 (TR)
Title: Tabanca mekanizmasında mukavemet arttırıcı destek sistemi.
Inventor: YIGIT ZAFER
IPC: F41A3/54
Filed: 2010-07-05
Abstract: Bu buluş "tabanca mekanizmasında mukavemet arttırıcı destek sistemi" ne ilişkindir. Kolay şekillendirilebilen ve seri imalata uygun plastik, zamak, alüminyum gibi yumuşak materyallerden yapılan tabanca mekanizmalarının kopma, ezilme ve aşınma gibi etkilerini azaltmak için daha güçlü materyallerden imal edilmiş destek sacı türünde bölgesel parçalarla destekleme sistemidir.
Patent DE-3587783-T2 (DE)
Inventor: BERGER ABE
IPC: C08G73/10
Filed: 1985-05-29
Granted: 1994-09-22
Abstract: Aromatic or aliphatic dianhydrides and/or acid anhydrides are reacted with aromatic diamines of formula (a) alone or in combination with other diamines to produce polyimides, polyamide acids, poly(amide-imides), poly(amide-amide acids), poly(esterimides) or poly)esteramide acids). These polymers are thermoplastic in nature and have improved processing characteristics and thermal stability. The polymers may be prepared by either melt or solution polymerization techniques.wherein R<sup>1</sup>, R<sup>2</sup> and R<sup>3</sup> each independently is hydrogen, halogen or unsubstituted or substituted hydrocarbyl,X<sub>1</sub> and X<sub>2</sub> each independently is substituted or unsubstituted branched, linear or cyclic alkylene or alkenylene of 1 to about 30 carbon atoms, -S-, or -O- with the proviso that X, or X<sub>2</sub> and may not both concurrently be -S- or -0-.n, n' and n" each independently is an integer of 1 to 4.
Patent DE-3688225-T2 (DE)
Inventor: BUELL N
IPC: C07K19/00
Filed: 1986-03-25
Granted: 1993-07-22
Abstract: A process for selecting DNA sequences that are optimal for the production of polypeptides in hosts transformed with those DNA sequences. These DNA sequences, which code for a variety of human and animal proteins, permit the high level expression of those products in hosts cells. In the preferred embodiment of this invention, DNA sequences optimal for the production of human somatomedin C are selected and employed to express that growth enhancing factor.
Patent DE-3688743-T2 (DE)
Inventor: ROGERS DAVID T
IPC: A21D8/04
Filed: 1986-11-07
Granted: 1993-11-04
Abstract: Process for increasing the rate of production of carbon dioxide, ethanol and other fermentation products such as citric acid, produced by yeast such as Saccaromyces cerevisiae during fermentation and decreasing biomass production by regulating the rate of glycolysis indirectly through changing the energy balance of the cell, i.e. by reducing intracellular ATP levels. Modifications for so altering the glycolysis rate involve the use of either a regulated ATP hydrolysis within the cell or a regulated leakage of ATP from the cell. This invention encompasses several ways for altering the yeast ATP level including (a) engaging futile metabolic cycles to increase ATP consumption; (b) using an altered exocellular acid phosphatase so that it becomes intracellular to increase intracellular ATP hydrolysis; (c) using a drug which uncouples the plasma membrane ATPase thereby consuming an abnormally high level of ATP; and (d) using a drug which allows the release of ATP from the cell to lower the intracellular ATP level. This invention further encompasses regulating the genetic modifications described in greater detail herein. By these means, such modifications may be turned off during growth of the yeast on a commercial scale, and then turned on before or during, and preferably before or at a very early stage of, the dough-rising phase.
Patent DE-3788485-T2 (DE)
Inventor: BROADBENT ELIOT KENT
IPC: H01L21/285
Filed: 1987-09-14
Granted: 1994-06-09
Abstract: A planar electrical interconnection system suitable for an integrated circuit is created by a process in which an insulating layer (31) having a planar upper surface is formed on a substructure after which openings (32) are etched through the insulating layer. A conductive planarizing layer (33) having a planar upper surface is formed on the insulating layer and in the openings by an operation involving isotropic deposition of a material, preferably tungsten, to create at least a portion of the planarizing layer extending from its upper surface partway into the openings. The planarizing layer is then etched down to the insulating layer. Consequently, its upper surface is coplanar with that of the material (33') in the openings. The foregoing steps are repeated to create another coplanar conductive/insulating layer (34 and 36'). If the lower openings are vias while the upper openings are grooves, the result is a planar interconnect level. Further planar interconnect levels can be formed in the same way.
Patent DE-3853288-T2 (DE)
Inventor: BASKIN DAVID
IPC: B44F9/04
Filed: 1988-06-07
Granted: 1995-11-09
Abstract: A cast simulated-stone containing flattened globules of overfilled, cured resin, which flattened globules substitute for natural stone chip additives and other such additives. The globules are formed by mixing an excess of a filler with a catalyzed liquid resin composition, the filler being added in an amount sufficient to cause the liquid to break apart into discrete, separable globules of resin composition. The globules are combined with a liquid resin composition and compressed and flattened in forming the simulated-stone.
Patent DE-3854948-T2 (DE)
Inventor: RATHMAN TERRY LEE
IPC: C07F3/02
Filed: 1988-03-29
Granted: 1996-11-14
Abstract: A method for producing methyllithium solutions by reacting a methylhalide with a mixture of lithium metal and an aromatic hydrocarbon containing tetrahydrofuran.
Patent DE-3886010-T2 (DE)
Inventor: ZAROTTI CLAUDIO
IPC: B60C17/00
Filed: 1988-10-10
Granted: 1994-06-09
Abstract: Inside a tight sealed chamber (2) defined between a rim (15) and a tire (1) of a pneumatic tire wheel for vehicles, there is provided a predetermined amount of a two-phase system in a substantially balanced state at the tire temperature and inflation pressure. The two-phase system comprises a liquid in a balanced state with its own vapor contained within a sealed, elastically deformable toric bladder (4) which is mounted to the rim. By changing the amount of heat in the two-phase system so as to change its balance condition, a variation is obtained in the inflation pressure of the tire (1).