Patent ES-8600858-A1 (ES)
Title: Concentrated emetic herbicidal composition and method for the preparation thereof.
IPC: A01N25/32
Filed: 1983-03-18
Abstract: EP--89413 A Herbicidal compsn. comprises an aq. soln. of 100-250 mg/ml. of a herbicidal 1,1'-dialkyl-4,4'-bipyridinium salt of formula (I), 10-20 mg/ml. of a peripherally acting emetic (II), 5-10 mg/ml. of a malodorous synergist (III) for (II) and 45-67.5 mg/ml. of a nonionic surfactant (IV). (R is 1-4C alkyl; X is an anion). The compsn. may also contain 0.5-0.75 mg/ml. silicone defoamer. - (I), which are highly effective herbicides (see GB-813531), are toxic to warm-blooded animals. The present compsn. promptly induces emesis following ingestion. Ingestion of sufficient compsn. to provide 6-13 mg. (II) and 3-4 mg. (III) per kg. body wt. reduces the time to onset of emesis by about 44% when contrasted with ingestion of a similar compsn. providing only 3-4 mg/kg. (II)  and 1-2 mg/kg. (III). - Animals ingesting the compsns. vomit only once or twice in the first 15 min. following ingestion whereas animals swallowing a similar compsn. contg. a centrally acting emetic show repeated vomiting i.e. up to 10 times in the first 2 hrs. following ingestion. In some instances these latter animals bring up bile from the stomach and faecal matter from the intestinal.  (0/1) EPAB- EP--89413 B Herbicidal compsn. comprises an aq. soln. of 100-250 mg/ml. of a herbicidal 1,1'-dialkyl-4,4'-bipyridinium salt of formula (I), 10-20 mg/ml. of a peripherally acting emetic (II), 5-10 mg/ml. of a malodorous synergist (III) for (II) and 45-67.5 mg/ml. of a nonionic surfactant (IV). (R is 1-4C alkyl; X is an anion). The compsn. may also contain 0.5-0.75 mg/ml. silicone defoamer. - (I), which are highly effective herbicides (see GB-813531), are toxic to warm-blooded animals. The present compsn. promptly induces emesis following ingestion. Ingestion of sufficient compsn. to provide 6-13 mg. (II) and 3-4 mg. (III) per kg. body wt. reduces the time to onset of emesis by about 44% when contrasted with ingestion of a similar compsn. providing only 3-4 mg/kg. (II)  and 1-2 mg/kg. (III). - Animals ingesting the compsns. vomit only once or twice in the first 15 min. following ingestion whereas animals swallowing a similar compsn. contg. a centrally acting emetic show repeated vomiting i.e. up to 10 times in the first 2 hrs. following ingestion. In some instances these latter animals bring up bile from the stomach and faecal matter from the intestinal.  (42pp Dwg.No.0/1) - EP--89413 B A concentrated emetic herbicidal composition comprising an aqueous solution of 100 to 250 Mg/ml of a salt of a herbicidal bipyridinium quaternary cation of the structural formula (I) wherein R is C1 alkyl and X is an anion; 10 to 20 mg/ml of the peripherally-acting emetic, sodium tripolyphosphate or tetra-potassium pyrophosphate; 5 to 10 mg/ml of the malodorous synergist, pyridine; and 45 to 67.5 mg.ml of a nonionic surfactant.  (21pp) GBAB- GB2116844 B A concentrated emetic herbicidal composition comprising an aqueous solution of about 100 to 250 mg/ml of a salt of a herbicidal bipyridinium quaternacation of the structural formula (I) wherein R is C1-4 alkyl and X is an anion, about 10 to 20 mg/ml of the peripherally-acting emetic, sodium triphosphate, or tetra-potassium pyrophosphate or mixtures thereof, about 5 to 10 mg/ml of pyridine, and about 45 to 67.5 mg/ml of a nonionic surfactant. USAB- US4432787 A Conc. emetic herbicidal compsn. comprises (a) an aq.soln. of 100-250 mg per ml. of the cation of 1,1'-dimethyl-4,4'-bipyridinium dichloride; (b) 10-20 mg. per ml of the peripherally-acting emetic sodium tripolyphosphate; (c) 5-10 mg. per ml. of the malodourous synergist pyridine for (b); and (d) 45-67.5 mg per ml of a nonionic surfactant. - Pref. the compsn. further comprises 0.5-0.75 mg per ml. of silicone defoamer and 45-67.5 mg per ml of the surfactant polyoxyethylene ethers of octyl and nonylphenols. - The herbicide used esp. comprises paraquat and is used for controlling growth of inter-row weed in vegetable crops and clearing weeds from pasture lanes.  (9pp)o