baber/WOPTO huggingface dataset:
Patent CA-3108088-A1 (CA)
Title: Late sv40 factor (lsf) inhibitors
Inventor: SCHAUS SCOTT EDWARD
IPC: A61K31/4741
Filed: 2019-08-02
Abstract: The present invention is directed to compositions, methods and kits for treatment of cancer, e.g. heptacellular carcinoma (HCC). In some embodiments, the present invention discloses the use of a small-molecule compounds of Formula (I)-(V) to inhibit tubulin methylation or to modulate chromatin or cytoskeleton modification in a cell.
Patent CA-3108869-A1 (CA)
Title: Systemes et procedes permettant d'identifier l'identite d'un produit
Inventor: OWEN NICHOLAS
IPC: G06Q30/00
Filed: 2019-08-09
Abstract: L'invention concerne la vérification d'identité d'un produit. En particulier, l'invention concerne un procédé permettant de vérifier l'identité d'un produit. Le procédé comprend une étape d'étiquetage qui consiste à générer une première séquence oligonucléotidique et à calculer une première valeur de hachage de la première séquence oligonucléotidique. La première valeur de hachage est associée au produit. Le procédé consiste ensuite à synthétiser la première séquence oligonucléotidique et à ajouter la séquence oligonucléotidique synthétisée au produit. Ensuite, une étape de test consiste à : séquencer une seconde séquence oligonucléotidique à partir du produit ; calculer une seconde valeur de hachage de la séquence oligonucléotidique séquencée ; et comparer la seconde valeur de hachage à la première valeur de hachage associée au produit pour vérifier l'identité du produit.
Patent CA-3110212-A1 (CA)
Title: Cooling system with oil return to accumulator
Inventor: ZHA SHITONG
IPC: F25B41/20
Filed: 2021-02-24
Abstract: A cooling system drains oil from low side heat exchangers to vessels and then uses compressed refrigerant to push the oil in the vessels back towards a compressor. Generally, the cooling system operates in three different modes of operation: a normal mode, an oil drain mode, and an oil return mode. During the normal mode, a primary refrigerant is cycled to cool one or more secondary refrigerants. As the primary refrigerant is cycled, oil from a compressor may mix with the primary refrigerant and become stuck in a low side heat exchanger. During the oil drain mode, the oil in the low side heat exchanger is allowed to drain into a vessel. During the oil return mode, compressed refrigerant is directed to the vessel to push the oil in the vessel back towards a compressor.
Patent CA-3110495-A1 (CA)
Inventor: EINZIGER MICHAEL
IPC: A61K31/404
Filed: 2019-08-23
Abstract: The present invention relates to compounds, compositions, and methods for modulating skin pigmentation and treating or preventing UV-induced skin damage, erythema, aging of the skin, sunburn, and hyperpigmentation in a subject. The compounds, compositions, and methods of the present invention generally involve Malassezia- derived compounds, including malassezin and indirubin, and/or chemical analogs thereof. Other applications of the compounds and compositions disclosed herein include, but are not limited to, improving hyperpigmentation caused by a hyperpigmentation disorder, inducing melanocyte apoptosis, and modulating atylhydrocarbon receptor (AhR) activity, melanogenesis, melanin production, melanosome biogenesis, melanosome transfer, melanocyte activity, and melanin concentration.
Patent CA-3113431-A1 (CA)
Inventor: BALANDIER QUENTIN LUC
IPC: F01D5/02
Filed: 2021-03-29
Abstract: The present invention provides a bladed rotor wheel for a gas turbine engine comprising at least a rotatable forged disc, the rotatable forged disc comprising a front surface and a back surface, at least one rim surface, and a plurality of projections located on at least a portion of at least one of the front or back surface and/or on the rim surface; wherein the projections are 3D printed features protruding outwards from the front, back and/or rim surface; the projections are arranged forming a pattern so that a heat transfer capability is created at the front, back and/or rim surface; and the ratio of the distance between projections to the forged disc external radius is lower than 0.15. Furthermore, the present invention also provides a method for manufacturing a rotatable forged disc for a bladed rotor wheel.
Patent CA-3113959-A1 (CA)
Title: Proline-locked stapled peptides and uses thereof
Inventor: HAYASHI KAZUHIRO
IPC: C07D207/16
Filed: 2013-09-26
Abstract: The present invention provides compounds of Formula (III), salts or stereoisomers thereof, wherein P is 1; K is unsubstituted alkylene; Ra is acetyl or Fmoc; Rb is -OH and x is 0.
Patent CA-3114640-A1 (CA)
Title: Active and passive refrigeration systems for downhole motors
Inventor: PIRES JUAN CRUZ
IPC: F04D13/08
Filed: 2019-09-27
Abstract: A pumping system has a motor, a shaft assembly connected to the motor, a production pump connected to the shaft assembly and driven by the motor, an electrical generator connected to the shaft assembly and driven by the motor, an oil circulation pump connected to shaft assembly and driven by the motor, and a heat exchanger. The heat exchanger includes an outer housing, a heat exchange core inside the outer housing, a plurality of heat exchange fluid passages extending through the heat exchange core, and one or more thermoelectric cooling modules in contact with the outer housing and the heat exchange core. The one or more thermoelectric cooling modules are powered by the output from the electrical generator. The oil circulation pump circulates motor lubricant oil between the motor and the heat exchanger.
Patent CA-3116110-A1 (CA)
Title: A modular, transportable plug-in ammonia producer
Inventor: GORDON ROGER
IPC: C01C1/02
Filed: 2021-04-26
Abstract: A plugin modular, transportable ammonia producing machine is developed that can conveniently produce ammonia from electricity, air and water. The invention includes ammonia synthesis through a plugin modular device. Figure 5 depicts the overall process flow of the system. Water at state 1 enters the system at room temperature in the water storage tank.  Next, at state 2, the water in the storage tank is sent to the circulation pump that delivers water to the air compressor.  This is done for two main purposes. Firstly, the circulating water cools the compressor during operation. Secondly, as the circulating water rises in temperature while leaving the air compressor, its temperature increases. This results in an increased inlet water temperature to the proton exchange membrane (PEM) electrolyser that leads to higher water electrolysis performance.
Patent CA-3116314-A1 (CA)
Title: Anticorps monoclonaux diriges contre la dickkopf3 humaine et leurs utilisations
Inventor: HWANG ROSA
IPC: A61K39/395
Filed: 2019-10-15
Abstract: L'invention concerne des méthodes et des réactifs permettant d'augmenter la chimiosensibilité à la chimiothérapie et à l'immunothérapie chez des patients atteints d'un cancer. L'invention concerne des méthodes de traitement du cancer, consistant à administrer à un patient en ayant besoin une quantité efficace d'un agent neutralisant la protéine DKK3, tel qu'un anticorps neutralisant la protéine DKK3 selon l'invention. Les méthodes peuvent en outre consister à administrer une quantité efficace de chimiothérapie ou d'immunothérapie audit patient.
Patent CA-3119609-A1 (CA)
Inventor: SKIDMORE ROGER RAY
IPC: H04W4/02
Filed: 2019-11-15
Abstract: Selon l'invention, un contenu de réalité augmentée (AR) peut être créé et stocké sous la forme d'une empreinte sur un modèle virtuel, le modèle virtuel étant calqué sur ou imitant un environnement du monde réel. Des interfaces intuitives de dispositif mobile peuvent être utilisées pour lier du contenu à des objets ou surfaces proches d'un dispositif mobile. Les utilisateurs ultérieurs peuvent accéder au même contenu en fonction d'un ou plusieurs paramètres d'accès.
Patent CA-3120836-A1 (CA)
Title: Electronic device
Inventor: TROESTER RAINER
IPC: H04W64/00
Filed: 2021-06-02
Abstract: An electronic device for securely determining current location information regarding the electronic device, the electronic device comprising a radio communication module and a secure element including a processor and a memory, the secure element being connected to the radio communication module and the processor being configured to obtain one or more beacon messages from one or more beacon devices; determine in real-time the current location information, the current location information comprising one or more distances between the electronic device and the beacon devices; and store the current location information in the memory of the secure element.
Patent CA-3121050-A1 (CA)
Title: Material washing apparatus
Inventor: ROONEY NEIL
IPC: B03B5/00
Filed: 2021-06-03
Abstract: A washing apparatus comprises a tank in which rotatable, bladed shafts are located. The tank has a closable lower outlet located at a first end of the tank, and an upper outlet located at the first end of the tank, the upper outlet being higher than the lower outlet. A further outlet is located at a second end or between the first and second ends. The tank is disposed at an inclined angle such that the first end of the tank is lower than the second end of the tank, and is movable between a first inclined state in which the inclined angle is relatively shallow, and a second inclined state in which the inclined angle is relatively steep. The apparatus is able to perform the tasks of either a log washer or coarse material washer depending on the angle of inclination.
Patent CA-3125477-A1 (CA)
Title: Drill rod with internal fluid bypass porting
Inventor: PRIMEVERT VINCENT
IPC: E21B17/18
Filed: 2020-01-09
Abstract: A drill rod can include a body having an outer surface, an inner surface, a longitudinal axis aligned with a drilling axis, and at least one longitudinally extending groove extending radially outwardly from the longitudinal axis relative to the inner surface. The inner surface and the at least one longitudinally extending groove can cooperate to define an interior space through which an inner assembly can be received as the inner assembly is advanced and retracted relative to the drilling axis. The at least one longitudinally extending groove of the body of the drill rod can be configured to permit axial flow of fluid through the drill rod as portions of the inner assembly engage the inner surface of the body of the drill rod.
Patent CA-3127947-A1 (CA)
Inventor: SCHREIER STEFAN
IPC: G01N33/543
Filed: 2020-02-06
Abstract: La présente invention concerne un procédé et un dispositif d'isolement de cellules non magnétiques d'une solution d'échantillon hétérogène contenant un matériau biologique comprenant des cellules souhaitées et non souhaitées. Le procédé comprend les étapes suivantes : - ajout de particules magnétiques ou magnétisables à l'échantillon, lesdites particules ayant des tailles dans une plage de 100 nm à 4 µm et présentant des composants de surface qui supportent une association spécifique avec des cellules cibles, lesdites cellules cibles comprenant soit lesdites cellules souhaitées soit lesdites cellules non souhaitées ; - diminution dudit gradient de champ magnétique externe ; - incubation de ladite solution d'échantillon avec lesdites particules magnétiques pour obtenir une fraction cellulaire magnétisée ; - lavage de ladite fraction cellulaire magnétisée à l'aide d'une solution de lavage pour réduire la liaison non spécifique ; - augmentation dudit gradient de champ magnétique externe ; - séparation de ladite fraction cellulaire magnétisée des cellules cibles dudit échantillon ; ladite solution d'échantillon étant soumise à un gradient de champ magnétique externe tout au long desdites étapes d'ajout, d'incubation, de lavage et de séparation, et ladite solution d'échantillon étant mise en rotation au moins pendant lesdites étapes d'ajout, d'incubation et de lavage.
Patent CA-3128706-A1 (CA)
Title: Methods and systems for controlled deployment of needle structures in tissue
Inventor: MUNROW MICHAEL A
IPC: A61M25/06
Filed: 2013-09-06
Abstract: A system for deploying needles in tissue includes a controller and a visual display. A treatment prove has both a needle and tines deployable from the needle which may be advanced into the tissue. The treatment probe also has adjustable stops which control the deployed positions of both the needle and the tines. The adjustable stops are coupled to the controller so that the virtual treatment and safety boundaries resulting from the treatment can be presented on the visual display prior to actual deployment of the system.
Patent CA-3129337-A1 (CA)
Title: Combinations of beta-lactam compounds and probenecid and uses thereof
Inventor: DUNNE MICHAEL
IPC: A61K31/00
Filed: 2019-12-23
Abstract: The present disclosure relates to bilayer tablets comprising a second layer comprising a ß-lactam compound or a pharmaceutically acceptable salt thereof; and a first layer comprising probenecid or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating or preventing a disease using the bilayer tablets.
Patent CA-3130154-A1 (CA)
Title: Pyrazolopyridine derivatives as inhibitors of pask
Inventor: BEAUMONT STEPHANE NICOLAS ALAIN
IPC: A61P3/00
Filed: 2020-02-17
Abstract: The present invention discloses compounds according to Formula I: wherein R1, R2, R3a, R3b, Het, X and the subscript n are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of endocrine, nutritional, metabolic, and/or cardiovascular diseases by administering the compound of the invention.
Patent CA-3130819-A1 (CA)
Title: Electronic lock
Inventor: BARNETT III STREET ANTHONY
IPC: E05B9/04
Filed: 2020-04-04
Abstract: The present disclosure generally relates to a lock including a blocker (e.g., a bolt) useable to selectively prevent access through a portal such as a door. The blocker can be retained in a blocking position to prevent access through the portal by a retainer. In alternative embodiments, the blocker can also be retained in an open position to allow access through the portal. A retainer can be utilized to retain the blocker in the blocking position preventing access through the portal and can also be utilized, in certain embodiments, to retain the blocker in the open position to allow access through the portal. A retainer blocker can be utilized to maintain the retainer in position to retain the blocker (e.g., bolt) in a fixed position. An actuator may, in certain alternative embodiments, be employed to position the retainer blocker. In certain embodiments, the actuator is controlled by an electronic controller.
Patent CA-3132033-A1 (CA)
Title: Composition for making a drilling fluid a non-invasive drilling fluid
Inventor: VASSHUS JAN KRISTIAN
IPC: C09K8/02
Filed: 2020-03-13
Abstract: The invention relates to a composition for making a drilling fluid a non-invasive drilling fluid, the composition comprising: a first component comprising particles having a scratch hardness above 2 Mohs; and a second component comprising particles selected from the group of frag-mented seeds of Tamarindus indica, comminuted bark from Litsea glutinosa, or comminuted Ocimum tenuiflorum. The invention further relates to a non-invasive drilling fluid comprising the composition, and a method for drilling a wellbore.
Patent CA-3133194-A1 (CA)
Title: 5-spirocyclohexyl-3-pyrroline-2-ones a substitution 3-(2-brome-4-alkinyl-6-alcoxyphenyl) et leur utilisation comme herbicides
Inventor: BOJACK GUIDO
IPC: A01N43/38
Filed: 2020-03-09
Abstract: L'invention concerne de nouvelles pyrroline-2-ones à substitution 3-(2-brome-4-alkinyl-6-alcoxyphényl), à action herbicide, de formule générale (I) ou des sels agrochimiquement acceptables de celles-ci, ainsi que leur utilisation pour lutter contre les plantes adventices et les mauvaises herbes dans des cultures de plantes utiles.
Patent CA-3133724-A1 (CA)
Inventor: SARDES AHISHAY
IPC: B60G3/01
Filed: 2020-04-16
Abstract: Certains modes de réalisation peuvent concerner une unité de suspension qui peut comprendre un rail ayant un axe longitudinal, un élément coulissant relié de façon coulissante au rail, et un moyen d'absorption et de suspension de choc conçu pour amortir les mouvements et supporter les forces le long de l'axe longitudinal du rail, le rail et l'élément coulissant étant formés de manière à présenter des profils transversaux qui empêchent un mouvement de rotation de l'élément coulissant par rapport au rail autour de l'axe longitudinal du rail. Selon certains modes de réalisation, l'unité de suspension peut faire partie d'un système intégré à la roue comprenant en outre au moins une unité de direction.
Patent CA-3134921-A1 (CA)
Inventor: PERUMALLA SATHYANARAYANA REDDY
IPC: B01L3/02
Filed: 2020-03-23
Abstract: A handheld solids dispenser. The dispenser includes a housing defining an inlet passage and an outlet passage. A delivery mechanism is supported within the housing and is positioned between the inlet passage and the outlet passage. Actuation of the delivery mechanism causes the delivery mechanism to transport a desired amount of solids material from the inlet passage to the outlet passage. The delivery member may be in the form of a plunger slidably positioned within the housing. The delivery mechanism may be in the form of a screw conveyor driven by a drive motor.
Patent CA-3137720-A1 (CA)
Title: Methods and systems for microsatellite analysis
Inventor: GARNER HAROLD
IPC: C12Q1/6886
Filed: 2020-04-21
Abstract: The present disclosure provides methods and systems for classifying microsatellite and minor alleles in a sample. Also, the present disclosure provides methods and systems for generating classifiers for conditions based on microsatellite loci and for performing pan-cancer assays. The methods and systems can involve next-generation sequencing of nucleic acid samples from subjects and genotyping microsatellite loci in the samples.
Patent CA-3140872-A1 (CA)
Inventor: RODGERS BRADFORD J
IPC: A01K63/10
Filed: 2020-06-18
Abstract: A mort trap assembly includes an upper ramp with a top end, a first bottom end, and an outer edge that is fixedly attached to an inner edge of a slide. A retaining chamber is located below the upper ramp and includes a first entry port located below the first bottom end of the upper ramp. A lower ramp has a top end spaced away from the upper ramp, and a first bottom end located at a bottom of the first entry port of the retaining chamber, and a purge pipe fluidly connected to the retaining chamber. The upper ramp is configured to receive morts from the slide, and the lower ramp is configured to receive the morts from the upper ramp and to direct the received morts into the first entry port.
Patent CA-3141329-A1 (CA)
Inventor: WANG QIN
IPC: G06F17/00
Filed: 2021-12-08
Abstract: The present application relates to the request link tracing field, and more particularly to a request link tracing method and a business request processing method. The request link tracing method comprises: storing received link tracing data after receiving the link tracing data uploaded by any service node, obtaining a link tracing identification of a request link associated with a request link tracing command when the request link tracing command is received, obtaining link tracing data related to the request link from all pre-stored link tracing data according to the link tracing identification of the request link, and displaying request link information according to the obtained link tracing data related to the request link. Embodiments of the present invention enable realization of tracing the entire link of a business request based on business transparent unique identification (ID).
Patent CA-3142019-A1 (CA)
Inventor: SCOTT DAVID A
IPC: C07K14/195
Filed: 2020-06-12
Abstract: L'invention concerne de nouveaux systèmes, procédés et compositions pour la manipulation ciblée d'acides nucléiques. L'invention concerne des systèmes CRISPR génétiquement modifiés, non naturels, des composants et des procédés de modification ciblée d'acides nucléiques tels que l'ADN. Chaque système comprend un ou plusieurs composants protéiques et un ou plusieurs composants d'acides nucléiques qui constituent ensemble des acides nucléiques cibles.
Patent CA-3143937-A1 (CA)
Title: Gaming content recommendation based on gaming performance
Inventor: NAIR GOVIND RAVEENDRANATHAN
IPC: A63F13/67
Filed: 2020-12-17
Abstract: Systems and methods for recommending video game content based on video game performance are disclosed. A level is identified from among a sequence of playable levels of a currently active video game. A video game performance metric for the identified level is determined. Based on the determined video game performance metric, a video of a performance of the identified level of the video game is selected for recommendation from among a plurality of videos stored in a database in association with corresponding video game performance metrics. An option, which is selectable to cause playback of the selected video, is transmitted for display via a computing device.
Patent CA-3145755-A1 (CA)
Inventor: HARRER HUBERT
IPC: H01H71/50
Filed: 2020-04-16
Abstract: The invention relates to a circuit breaker (12), in particular of a power breaker (10), comprising a busbar (32) which is mounted so as to be movable between a closed position (84) and an open position (80); a trip device (16); a hand lever (66) which can be moved between a first position (70) and a second position (82); and a mechanism (24). The busbar (32), the trip device (16) and the hand lever (66) are coupled by means of the mechanism (24) in such a way that, when the hand lever (66) is moved from the first position (70) into the second position (82), the busbar (32) is moved from the open position (80) into the closed position (84). Upon tripping of the trip device (16), the busbar (32) is moved from the closed position (84) into the open position (80), and the hand lever (66) is moved from the second position (82) into the first position (70), if it is not blocked. When the hand lever (66) is moved from the second position (82) into the first position (70), the busbar (32) is moved from the closed position (84) into the open position (80) regardless of whether the busbar (32) is blocked in the closed position (84).
Patent CA-3146102-A1 (CA)
Inventor: HOOPER MATHEW J
IPC: G01S7/56
Filed: 2022-01-19
Abstract: Systems and methods for providing a sonar beam footprint are detailed herein.  A system for presenting marine data includes at least one sonar transducer associated with a watercraft, a display, processor(s), and memory including computer program code. The sonar transducer emits sonar beams into an underwater environment that define a beam shape. The program code, when executed, causes, on the display, presentation of a chart and a representation of the watercraft; determines a depth corresponding to a bottom surface of a body of water at a current location of the watercraft; and determines, based on the depth and the beam shape, a sonar beam footprint corresponding to a projection of the beam shape at the depth. The program code further causes, on the display, presentation of the sonar beam footprint on the chart so as to visually indicate sonar beam coverage.
Patent CA-3147163-A1 (CA)
Inventor: SINGH SUDARSHAN B
IPC: A61F2/16
Filed: 2020-08-21
Abstract: L'invention concerne des systèmes, des méthodes et des appareils pour fixer de manière amovible une pièce à main de mécanisme d'entraînement à une cartouche de lentille intraoculaire (LIO) qui plie la LIO lors de la rétraction d'un capuchon. La cartouche de LIO comprend une buse et un compartiment configuré pour recevoir une LIO. La buse est en communication fluidique avec le compartiment. La cartouche de LIO comprend également un capuchon rétractable qui recouvre la buse et le compartiment. Le capuchon rétractable est configuré pour exposer la buse et plier la LIO lors de la rétraction du capuchon rétractable. La cartouche de LIO peut également comprendre un boîtier de piston qui est en communication fluidique avec le compartiment, un piston étant disposé de manière mobile à l'intérieur du boîtier de piston.