baber/WOPTO huggingface dataset:
Patent NZ-320352-A (NZ)
Title: 3-spiro-indolin-2-one derivatives as vasopressin and/or oxytocin receptor ligands
Inventor: FOULON LOIC
IPC: A61P9/12
Filed: 1996-10-24
Abstract: The method and composition of Indolin-2-one derivatives and of general formula I wherein: W represents a -CH2-, or -SO2- group; Cy forms, with the carbon to which it is bonded, a non-aromatic, saturated or unsaturated C3-C12 hydrocarbon ring which is optionally condensed or substituted by at least one (C1-C6)alkyl groups; it being possible or the said groups to substitute the same carbon atom at least once, or by a C3-C6 spirocycloalkyl. T represents a (C1-C4)alkylene which is optionally interrupted by a (C3-C6)cycloalkylene, the said alkylenes optionally being substituted at least once on the same carbon atom by a (C1-C3)alkyl; or alternatively T represents a direct bond; Z represents a -NR11R12 group; +NR11R12(C1-C4)-alkyl (A-), (A-) being an anion; N(O)R11R12; a -COOR11 group; an -NR11COR12 group; a benzyloxycarbonylamino; a -CONR11R12 group; it being understood that when T represents a methylene or a direct bond, Z cannot be -NR11R12, -+NR11R12(C1-C4)-alkyl, N(O)R11R12, , NR11 COR12, a benzyloxycarbonylamino. In addition where R1-R13, have any of the values defined in the specification. Also included in this invention is the use of said Indolin-2-one derivatives in the manufacture of a medicament for the treatment of vasopressin-dependent or oxytoxin-dependent complaints.
Patent NZ-329511-A (NZ)
Title: Elliticine derivatives and pharmaceutical compositions thereof
Inventor: GUILLONNEAU CLAUDE
IPC: A61P43/00
Filed: 1997-12-24
Abstract: Ellipticine derivatives of formula (I) and their optical isomers, N-oxides and acid or base addition salts are new. R1 = 1-6C alkyl; R2, R4, R5 = H or 1-6C alkyl; R3 = H, 1-6C alkyl (optionally substituted by di-(1-6C alkyl)-amino on the C bonded to the ring) or 2-6C alkenyl; R6, R7 = H or 1-6C alkyl; or NR6R7 = heterocycle (optionally containing a second N, O or S heteroatom); or R5+R6 = (CH2)m; m = 2 or 3; and A = 1-10C alkylene; provided that A is not 1-6C linear alkylene if R3 = H.
Patent NZ-500363-A (NZ)
Title: Mathematical boardgame involving use of subtraction, multiplication, addition or division and is configured to the skill level of the players
Inventor: SLATTER NARELLE ANNE
IPC: A63F3/00
Filed: 1998-01-28
Abstract: A mathematical boardgame, the board consists of one hundred and forty four spaces which are numbered. Players move horizontally from left to right, right to left and so on through to the nominated Finish Award. Players move by use of a spinner which then indicates one of four mathematical formats one plays. This could be Subtraction, Multiplication, Addition or Division, also the player to commence the game is indicated by the spinner. Players move by means of answering a mathematical sum, which is given a value by an Answer Value Chart, which converts the sum of the problem to a given value. The player moves that number of spaces and receives from the Bank that amount of money. Because of the special Answer Value Charts, players from six years old to adults can be on equal levels. The board, spinner, cards, name of the game, money, symbols, all these inter-connect. The winner is the player with the highest amount of money at the end of the game.
Patent NZ-502849-A (NZ)
Title: Method for increasing muscle protein and reducing fat in animals by administration of gastro-intestinal (GI) hormones
Inventor: ADALSTEINSSON ORN
IPC: A23K1/16
Filed: 1998-08-18
Abstract: A method for achieving at least one of the following: increasing muscle protein or reducing fat in an animal, the method comprising administering to an animal a composition comprising an effective amount of an antibody, wherein the antibody comprises a gastrointestinal neuro-modulator antibody and wherein administration of the composition results in either an increase in muscle protein or a reduction of fat in the animal. Suitable gastrointestinal neuro-modulator are any compositions that influences gastrointestinal motility, including regulatory peptides, neurotransmitters, hormones and immune-regulators, such as cholecystokinin (CCK), bombesin, and gastrin among many others.
Patent NZ-504358-A (NZ)
Title: Tamper-evident form for securely carrying information
Inventor: SCHEGGETMAN BERNARD WILLEM WIM
IPC: B42D25/30
Filed: 1998-09-18
Abstract: A tamper-evident form for securely carrying information includes a scrambling pattern (4), which underlies the printed information such that the printed information cannot be read. Separation of the printed information and scrambling pattern, or other disabling of the scrambling pattern, is tamper-evident and renders the information readable. In preferred embodiments the information is printed on a lamina (6A), which overlies the scrambling pattern (4). Conventional printers can print the information and no post-processing of the form is required to render the information secure.
Patent NZ-504880-A (NZ)
Title: Incinerator for removing noxious substances with a removal section and where a vacuum is maintained in the burning section
Inventor: MAEJIMA TAKASHI
IPC: F23G5/24
Filed: 1998-09-07
Abstract: An incinerator (1) for removing noxious substances from a flue gas, characterized by comprising an incineration section (2) adapted to burn an object material (5) therein, a removal section (2a) adapted to remove noxious substances occurring in the incineration section (2) and joined to the above section, and a suction vacuum means or an air supply vacuum means adapted to generate a flow of air advancing from the incineration section to the removal section, so as to keep the interior of the incineration section in a vacuum at all times.
Patent NZ-509804-A (NZ)
Title: Fusion peptides and their corresponding nucleic acids comprising a collagen binding domain and an angiogenesis modulating agent useful for local induction of angiogenesis
Inventor: ANDERSON W FRENCH
IPC: A61K39/395
Filed: 1999-07-30
Abstract: The present invention provides new compositions and methods to induce therapeutic angiogenesis locally utilizing a collagen binding domain to target an angiogenesis modulating agent. Fusion poly peptides containing a collagen binding domain linked to an angiogenesis modulating agent are provided, as are nucleic acid sequences encoding the fusion polypeptides. Also included are methods for locally altering circulation by administering a fusion polypeptide consisting of a collagen binding domain linked to an angiogenesis modulating agent, or by administering a nucleic acid sequence encoding the fusion polypeptide. Tissue grafts in which isolated tissue is treated with a fusion polypeptide consisting of a collagen binding domain linked to an angiogenesis modulating agent, or with a nucleic acid sequence encoding the fusion polypeptide are also provided, as are methods of making the grafts.
Patent NZ-510173-A (NZ)
Title: Novel nitrophenylaziridine compounds and their use as prodrugs
Inventor: PALMER BRIAN DESMOND
IPC: A61K38/44
Filed: 1999-09-07
Abstract: The use of a compound of formula (I), wherein; X is CO or SO2; Y is H, or optionally substituted alkyl; R1 is H, halo, NO2, N3, CN, SOCH2Y, SO2CH2Y, COCH2Y, SONHY, SO2NHY, CONHY, CO2Y, an optionally substituted alkyl group or the replacement of one -CH= in the aromatic ring with -N=; R2 represents the optional presence of methyl or ethyl; For use in the manufacture of a medicament for the treatment of neoplastic disease in combination with a nitroreductase enzyme.  Also described is a two-component system for the treatment of neoplastic disease comprising a compound of formula (I) and a vector encoding and capable of expressing a nitroreductase enzyme in a tumour cell.
Patent NZ-516112-A (NZ)
Title: Linearly motile infusion pump
Inventor: DANBY HAL C
IPC: F04B13/00
Filed: 2001-03-15
Abstract: An ambulatory infusion pump (10) has a syringe  barrel (16)  having  a  fluid chamber and an inner wall  (22).  The pump  (10)  further has an infusion engine (14)  for  moving fluid  through the syringe barrel (16). The infusion  engine (14)  has  a  member  (42) for engaging  a  portion  of  the syringe  barrel  (16)  for moving the engine  (14)  linearly along the syringe barrel (16).
Patent NZ-517833-A (NZ)
Title: Oral delivery of antioxidants vitamin C and vitamin E combinations in slow- and plain-release formulations for treating oxidative stress
Inventor: HOJGAARD BENT
IPC: A61P25/28
Filed: 2000-08-18
Abstract: A pharmaceutical delivery system comprising a slow-release formulation of vitamin C (ascorbic acid) and a plain-release formulation of vitamin E (tocopherol), which has been found to raise and maintain the concentrations of these vitamins in the blood plasma to a ratio of approximately 2.2:1. The steady-state concentration and ratio of these antioxidants has been found to be critical in the prevention and treatment of oxidative stress related disorders such as arteriosclerosis, diabetes and neural degenerative disorders such as Alzheimer's disease.
Patent NZ-520702-A (NZ)
Title: Barbecue grill assembly with a shelf component
Inventor: STEPHEN ROBERT T
IPC: A47J37/07
Filed: 2002-08-09
Abstract: Disclosed herein is a barbecue grill assembly (10) comprising an upper frame assembly (12) and a lower frame assembly (14). The lower frame assembly (14) comprises a shelf (50) and a plurality of lower frame members (26, 28) that define an interior space (40). At least one frame member (28) has an aperture (80). The shelf (50) has at least one pin (70) cooperatively dimensioned with the aperture (80). The pin (70) is received by the aperture (80) to connect the shelf (50) to the lower frame members (26, 28) and form the lower frame assembly (14). The shelf (50) has a perimeter that is cooperatively dimensioned with the interior space (40) such that the shelf (50) is positioned within the interior space (40). The shelf (50) provides structural integrity to the lower assembly (14) such chat the lower assembly (14) can support the upper assembly (12) and the cooking chamber (16).
Patent NZ-522929-A (NZ)
Title: Overcap closures with rolled apron
Inventor: CHRISTOPHE PHILIPPE
IPC: B65D41/62
Filed: 2001-07-04
Abstract: Disclosed is an overcap (1, 12) comprising a rolled skirt (3) and a head (2) fixed to said rolled skirt, along a circular junction zone (4) common to said skirt and said head. The invention is characterized in that the head is made of a first material capable of being deformed to form a head with fold-free rim, the rim having an axial height between 1 and 5 mm, the rolled skirt comprises an upper end, necked-in over at least a width of 1 mm, co-operating with the rim to form the circular junction zone, the rolled skirt being made of a second strip material with lower mechanical properties than those of the first material, the circular junction zone, common to the rim and to the upper end, extends over a width not less than 0.5 mm.
Patent NZ-526092-A (NZ)
Title: Waste treatment process
Inventor: JONES IAN
IPC: C02F1/52
Filed: 2001-10-30
Abstract: A process of waste treatment which involves: (a) separation of waste material to provide a component having a concentrated solids component and a predominantly liquid component; (b) passing the concentrated solids component through an anaerobic bioreactor system and maintaining insoluble material as a suspension in the concentrated solids component; (c) removing phosphorous and/or nitrogen from the concentrated solids component and/or the predominately liquid component; and (d) removing solids from the concentrated solids component.
Patent NZ-526108-A (NZ)
Title: Use of optically pure (-) norcisapride in the treatment of bulimia
Inventor: RUBIN PAUL D
IPC: A61P25/00
Filed: 1999-06-10
Abstract: Disclosed is the use of (-) norcisapride, substantially free of its (+) stereoisomer, for the manufacture of a pharmaceutical composition for treating bulimia in a patient.
Patent NZ-528759-A (NZ)
Title: Use of heat in cold storage appliances
Inventor: WOOD IAN DAVID
IPC: A47B88/493
Filed: 2002-03-13
Abstract: A cooling unit (2) having at least one container (16) defining external surfaces including first and second external surfaces; a container compartment (4) for the at least one container (16) and heating means (38) for warming at least the first and second external surfaces of the container (16) when it is in the container compartment (4).
Patent NZ-529843-A (NZ)
Title: Synergistic herbicidal methods and compositions
Inventor: PIDSKALNY RONALD STEVEN
IPC: A01N43/40
Filed: 2000-10-12
Abstract: The present invention provides a method for the synergistic control of undesirable plants such as Polygonum, Kochia, Galeopsis, Galium, Stelaria, Sinapis, and Avena which comprises applying to the plants or their locus a synergistically effective amount of an aryloxypicolinamide herbicide in combination with one or two selected additional herbicidal compounds. Further provided are synergistic herbicidal compositions comprising an aryloxypicolinamide herbicide arid one or two selected additional herbicidal compounds.
Patent NZ-530030-A (NZ)
Title: Remote control of local controllers for an irrigation system
Inventor: TOWNSEND JAMES DUNSTONE
IPC: A01G25/16
Filed: 2002-06-06
Abstract: Various locations are each provided with a programmable location controller 10 that can cause or permit a prescribed event or events (such as the opening or closing of relays 11 to control valves V1 to V5 )to be carried out at that location. Each location controller can receive control commands, by radio signal 21 for example, from a remote controller to influence the events that are controlled by the location controller. The location controllers are each provided with at least two default settings to govern implementation of the prescribed event at the location if it happens that the commands from the remote controller are not received. The control system is particularly adapted to the remote control of the valves of a water irrigation system.
Patent NZ-535242-A (NZ)
Title: Method for identifying the cellular factors responsible for cell differentiation that begins with the random cloning of expressed genes by use of a cDNA library, the cDNA being from a beginning cell type
Inventor: THOMSON JAMES A
IPC: C12Q1/68
Filed: 2003-03-14
Abstract: A method for identifying the genetic factors responsible for cell differentiation based on expression cloning is described. To determine what genetic factor leads to the differentiation of a cell from a beginning cell type to a target cell type, a cDNA library is obtained, packaged in an expression vector and transformed into cells of the beginning cell type. The expression vector also preferable includes a marker gene system under the control of a tissue specific promoter operable in the tissue type of the target cell type. The transformed cells are then cultured until cell differentiation begins, then the culture is screened or selected to identify the cells which undergo differentiation toward the target cell type. By examining the cDNA insert in the differentiated cells, the genetic factor responsible for the differentiation process can be identified.
Patent NZ-536612-A (NZ)
Title: Compositions derived from a lactational secretion such as milk or colostrum having anti-metalloproteinase activity for the treatment of wounds and disorders of the gastrointestinal tract
Inventor: GODDARD CHRISTOPHER
IPC: A61K38/00
Filed: 2003-06-06
Abstract: Provided are inhibitors of metalloproteinases that may be extracted from lactational secretions such as milk and colostrum. The inhibitors have use in the treatment of a range of diseases such as disorders of the gastrointestinal tract, cardiovascular conditions and wound healing. Methods for purifying the inhibitors are also disclosed.
Patent NZ-539060-A (NZ)
Title: A picket for a railing system
Inventor: WALKER SIMON
IPC: E04F11/18
Filed: 2005-03-29
Abstract: Describes a picket, as depicted in figure (I), for a railing system having a top rail and a bottom rail, the picket including an elongated tubular body having inner and outer walls and first and second ends for engaging the top and bottom rails, respectively. The inner wall defines a longitudinal bore through the elongated tubular body from the first end to the second end. The picket includes a reinforcing member connected to and extending away from the inner wall of the elongated tubular body.
Patent NZ-542956-A (NZ)
Title: Method for high throughput volumes in the fractionation of bio-molecules by chromatographic systems
Inventor: HANSEN MARIE BENDIX
IPC: C07K1/16
Filed: 2004-03-19
Abstract: To isolate bio-molecules from a fluid, such as protein from whey, on an industrial scale, the pH of the fluid is adjusted if desired, then brought to a temperature of at least 40 degrees Celcius then applied at a linear flow rate of at least 1500 cm/hr (25 cm/min) to an expanded bed adsorption column having an adsorbent also at 40 degrees. The column is optionally washed and the bio-molecule is then eluted from the adsorbent. By careful choice of adsorbent particle density and other properties and utilising the higher temperature, efficient adsorption of the bio-molecule may be accomplished at the high flow rates without degradation of the molecules.
Patent NZ-546045-A (NZ)
Title: Helical drag bit and method of using the same
Inventor: HILL JOHN L
IPC: E21B10/44
Filed: 2004-08-18
Abstract: Disclosed is a method of supporting a rock substrate. The method includes the steps of providing a hole in the substrate, inserting a rock bolt having a number of protuberances into the hole and using the protuberances to form a number of grooves in a wall of the hole. The step of inserting the rock bolt into the hole occurs after the step of providing the hole.
Patent NZ-548019-A (NZ)
Title: Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the ergosterol biosynthesis
Inventor: GROSJEAN-COURNOYER MARIE-CLAIRE
IPC: A01N43/40
Filed: 2005-02-10
Abstract: Disclosed is a fungicidal composition comprising (a) a pyridylethylbenzamide derivative of general formula (I), in which the substituents are as defined in the specification, and b) a compound capable of inhibiting the ergosterol biosynthesis selected from the group consisting of: i) a triazole derivative selected from the group consisting of azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simeconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triticonazole, diclobutrazole, etaconazole, fluotrimazole, furconazole, furconazole-cis, triamiphos and triazbutil; ii) an imidazole derivative selected from the group consisting of imazalil, prochloraz, oxpoconazole fumarate, pefurazoate and triflumizole; iii) a morpholine derivative selected from the group consisting of aldimorph, dodemorph, fenpropimorph and tridemorph; iv) a piperidine derivative selected from the group consisting of fenpropidin and piperalin, and v) a compound selected from the group consisting of fenhexamid, spiroxamine and triforine; in a (a) / (b) weight ratio of from 0.01 to 20. Reference has been directed, in pursuance of section 16(1) of the Patents Act 1953, to patent No. 537608.
Patent NZ-560225-A (NZ)
Title: Maleimide derivatives, pharmaceutical compositions and methods for treatment of cancer
Inventor: MOUSSA MAGDI M
IPC: A61K38/08
Filed: 2006-02-09
Abstract: Disclosed is a pyrroloquinolinyl-pyrrolidine-2,5-dione compound of one the formulas (IVa), (IVb), (Va), or (Vb), wherein m is 1 or 2 and the substituents are as defined in the specification. Also disclosed is the use of the compound for treating a cell proliferative disorder, such as cancer or a precancerous condition.
Patent NZ-562364-A (NZ)
Title: Reducing heat load applied to freeze wells using a heat transfer fluid in heat interceptor wells
Inventor: VINEGAR HAROLD J
IPC: B60L1/02
Filed: 2006-04-21
Abstract: Disclosed is a system for reducing heat load applied to a frozen barrier by a heated formation. The system comprises of: heat interceptor wells (504) positioned between the heated formation (502) and the frozen barrier (408); and fluid positioned in the heat interceptor wells. A least one heat interceptor well comprises a heat pipe configured so that heat from the formation vaporizes liquid in the heat interceptor well proximate to a heated section of the formation. Heat transfers from the formation to the fluid to reduce the heat load applied to the frozen barrier, and produced vapour rises in the heat interceptor well. The vapour condenses to liquid in the heat interceptor well, and the liquid falls by gravity to an area adjacent to the heated section of the formation.
Patent NZ-564399-A (NZ)
Title: Liquid for preventing tissue adhesion and method of preventing tissue adhesion using trehalose
Inventor: SUZUKI SHIGEKI
IPC: A61K31/7016
Filed: 2006-06-08
Abstract: Disclosed is the use of trehalose in a solution for tissue adhesion prevention, such as in surgery. Disclosed is the prevention of tissue and organ damage during surgery that would expose them to open air, such as tissue adhesion, by applying a solution which contains trehalose. A water solution of trehalose may be sprayed onto organs during a surgical procedure to prevent dehydration. The solution may include other agents suitable for the same purpose which are described in the specification.
Patent NZ-574393-A (NZ)
Title: Smac peptidomimetics useful as iap inhibitors
Inventor: CHAREST MARK G
IPC: A61K31/427
Filed: 2007-07-31
Abstract: Disclosed are pyrrolidine compounds, such as (S)-N-((S)-1-Cyclohexyl-2-{ (S)-2-[4-(4-fluoro-benzoyl)-thiazol-2-yl]-pyrrolidin-1-yl} -2-oxo-ethyl)-2-methylamino-propionamide and (S)-N-((S)-1-Cyclohexyl-2-{ (S)-2-[6-(4-fluoro-phenylamino)-2-methyl-pyrimidin-4-yl]-pyrrolidin-1-yl} -2-oxo-ethyl)-2-methylamino-propionamideor pharmaceutically acceptable salts thereof. The compounds are used to treat proliferated diseases.
Patent NZ-580126-A (NZ)
Title: Crystalline forms of 6- [2- (methylcarbamoyl) phenylsulfanyl] -3-e- [2- (pyridin-2-yl) ethenyl] indazole suitable for the treatment of abnormal cell growth in mammals
Inventor: MCLAUGHLIN ROBERT WILLIAM
IPC: A61K31/4439
Filed: 2008-03-25
Abstract: Disclosed is a crystalline form of 6-[2-(methylcarbamoyl)phenylsulfanyl]-3-E-[2-(pyridin-2-yl)ethenyl]indazole (compound 1 as depicted), wherein said crystalline form is a substantially pure polymorph of Form XLI having a powder X-ray diffraction pattern comprising a peak at diffraction angle 2 Theta as disclosed in the specification. Also disclosed is a pharmaceutical composition comprising the crystalline form XLI of the compound.
Patent NZ-584595-A (NZ)
Title: Methods for assaying melanocortin 1 receptor variants utilysing a mitochondrial DNA abberration which is a 3895 bp mtDNA deletion between nucleic acid 546 to 4444 of the mtDNA genome
Inventor: PARR RYAN
IPC: A61K45/00
Filed: 2008-10-14
Abstract: Disclosed is a diagnostic method for determining the skin state and genetic predisposition of a subject to UVR damage. The disclosed method comprises: assaying a skin sample from the subject for a mitochondrial DNA (mtDNA) aberration, wherein the aberration is a 3895 bp mtDNA deletion between nucleic acids 546 to 4444 of the mtDNA genome; assaying a tissue sample from the subject for one or more melanocortin receptor (MCIR) variants, wherein the one or more MCIR variants are selected from the group consisting of D84E, R142H, R151C, R160H, D294H, V60L, and V92M; and determining the skin state and genetic predisposition of the subject to UVR damage based on the detection of the mtDNA aberration and MCIR variant(s) in the skin and tissue samples, respectively.