baber/WOPTO huggingface dataset:
Patent CR-20120510-A (CR)
Title: Derivados de piperidin-4-il azetidina como inhibidores de jak1
Inventor: HUANG TAISHENG
IPC: A61K31/4155
Filed: 2012-10-08
Abstract: La presente invención proporciona derivados de piperidin-4-il azetidina, como también sus composiciones y métodos de uso, que modulan la actividad de Janus quinasa (JAK1) y son útiles en el tratamiento de las enfermedades relacionadas con la actividad de JAK1.
Patent CR-20190577-A (CR)
Title: Pharmaceutical compositions
Inventor: ALLGEIER MATTHEW CARL
IPC: A61K31/00
Filed: 2018-07-10
Abstract: The present invention relates to solid oral fixed dose compositions of metformin, atorvastatin, and valsartan, or their pharmaceutically acceptable salts, processes for the preparation thereof, and the use of the composition to treat certain diseases.
Patent EC-SP003542-A (EC)
Title: Metodo para moldear un producto alimenticio
Inventor: LEADBEATER JOHN MICHAEL
IPC: A23G1/21
Filed: 2000-06-23
Abstract: La presente invención se refiere a un método y aparato para el moldeo y enfriamiento rápido de un producto alimenticio, de preferencia un producto de confitería. El método comprende los siguientes pasos a) depositar un producto alimenticio solidificante en una serie de moldes unidos a un rodillo enfriado en donde el producto alimenticio se solidifica a menos parcialmente en el molde, b) hacer girar el rodillo enfriado para mover las series de moldes con producto alimenticio en contacto con una banda transportadora y suficientemente después de la deposición para evitar la distorción de la superficie superior del producto alimenticio conforme el molde se separa de la horizontal y c) separar el producto alimenticio al menos parcialmente solidificado de los moldes de la banda transportadora. Una modalidad alternativa de la presente invención, comprende un método para moldear un producto alimenticio que comprende los pasos de d) depositar un producto alimenticio solidificable en formasecuencial en una serie de moldes unidos a un rodillo enfriado en donde una placa enfriada se basa sobre el molde durante la deposición y en donde el producto alimenticio se solidifica al menos paracialmente en el molde, b) hacer girar el rodillo enfriado y c) separar el producto alimenticio al menos parcialmente solidificado de los moldes.
Patent EC-SP066791-A (EC)
Title: Compuestos azufrados como inhibidores de la serina proteasa ns3 del virus de la hepatitis c
Inventor: SAKSENA ANIL K
IPC: A61K31/403
Filed: 2006-08-25
Abstract: La presente invención revela nuevos compuestos que tienen actividad inhibidora de la proteasa del VHC como así también métodos para preparar tales compuestos. En otra realización, la invención revela composiciones farmacéuticas que comprenden tales compuestos como así también métodos para usarlos para tratar trastornos asociados con la proteasa del VHC.
Patent EC-SP099036-A (EC)
Title: Moduladores del metabolismo y tratamiento de los trastornos metabólicos
Inventor: LEHMANN JUERG
IPC: C07D401/14
Filed: 2009-01-06
Abstract: La presente invención se refiere al éster isopropílico del ácido 4-[6-(6-metanosulfonil-2-metil-piridin-3-ilamino)-5-metil-pirimidin-4-iloxi]-piperidin-l-carboxílico y sus sales, solvatos e hidratos farmacéuticamente aceptables que son moduladores del metabolismo de la glucosa. En consecuencia, los compuestos de la presente invención son útiles en el tratamiento de los trastornos metabólicos y las complicaciones relacionadas, como la diabetes y la obesidad.
Patent EC-SP920861-A (EC)
Title: Dispositivo de torbellino con estrangulador ajustable y metodo para estrangular la trayectoria de flujo fluido
Inventor: AYRES ROBERT N
IPC: E21B37/06
Filed: 1992-09-03
Abstract: El objetivo del presente invento es promover un disposotivo de entrada de fluidos para combinar los fluidos de producción de un pozo de petróleo y gas con ciertos quimicos para mejorar la producción en forma continua y automática y luego inyectar la mezcla en el pozo.
Patent EC-SP920869-A (EC)
Title: Bateria con probador o indicador electroquimico
Inventor: KUO HAN CHENG
IPC: H01M16/00
Filed: 1992-09-24
Abstract: La presente invención se relaciona con una pila alectroquímica y un indicador de estado de carga relacionado que comprende un display generado electroquímicamente. El estado del indicador de carga comprende dos contactos eléctricos y un display generado electroquímicamente conectado entre los mismos. El display comprende una pila electroquímica que puede estar conectada permanentemente a una pila principal en una configuración en paralelo por medio de los contactos.
Patent EC-SP993097-A (EC)
Title: Un metodo para la prevencion del inicio del asma
Inventor: UYLENBROECK LUC
IPC: C07D215/32
Filed: 1999-08-12
Abstract: La presente invención se refiere a un método para la prevención del inicio del asma que incluye la administarción a un paciente de una cantidad efectiva terapeuticamente de cetiricina, un isómero óptico individual de la misma o una sal farmacéuticamente aceptable de la misma.
Patent FI-20130366-A (FI)
Inventor: BACKMAN JAN
IPC: B04C/
Filed: 2013-12-03
Abstract: A hydrocyclone (1) for separating a liquid mixture into a heavy fraction including heavy particles and alight fraction, comprising a housing (2) forming an elongated separation chamber (3) having a circumferential wall (4), abase end (5),an apex end (6),at least one inlet member (7) for supplying a liquid mixture into the separation chamber (3), at least one of the inlet member/s(7) positioned at the base end (5), a first outlet member (8) for discharging separated light fraction from the separation chamber (3)at the base end (5), a second outlet member (9) for discharging separated heavy fraction from the separation chamber (3) at the apex end (6),means (10) for supplying the liquid mixture to the separation chamber (3) via the at least one inlet member (7), so that during operation a liquid stream is generated as a helical vortex (11) about a centre axis (12) in the separation chamber (3), said helical vortex (11) extending from the base end (5) to the apex end (6), a first flow deflection means arranged in the circumferential wall (4) which comprises at least one member(14) in the path 13 of the liquid stream showing a decrease of the radius of the separation chamber, followed by an increase of the radius of the separation chamber,where in the at least one member comprises a rounded curve portion 14a for transporting the heavy particles.
Patent FR-1601172-A (FR)
Title: Heating oven for rotary moulding of plas- - tics hollow bodies
IPC: B29C41/46
Filed: 1968-12-30
Granted: 1970-08-10
Abstract: Moulds on plates are rotated around axes perp. to a shaft which projects within the oven and is rotated around its own axis. A channel in the prolongation of the shaft which supports the moulds has orifices, and possibly deflectors, for feeding in hot into the central part of the oven.
Patent GB-1046898-A (GB)
Abstract: 1,046,898. Shoots and hoppers. E. KOSTER, K. KOSTER, and U. BRAND. Aug. 13, 1964, No. 33001/64. Heading B8S. A shoot suitable as a bunker and for vertical downward conveyance of material comprises a vertical pipe, e.g. of sheet metal, and a plurality of steps extending transversely of the pipe and alternately from opposite sides of the latter, each step comprising a front part having an arcuate section at its front edge which is adjustable in shape and dimensions. In a first embodiment, Fig. 1, each step comprises lamellµ 1 . . . 5 which are laterally adjustable relative to one another. In a second embodiment, Figs. 4 ... 6 (not shown), the front part comprises interchangeable inserts. In a third embodiment, Fig. 8, the front part comprises a plurality of sections a, b, c hinged to the body of the step d.
Patent GB-1053205-A (GB)
IPC: G01N30/30
Abstract: 1,053,205. Gas chromatography. SOUTH EASTERN GAS BOAD. Dec. 4, 1963 [Nov. 20, 1962], No. 43931/62. Heading B1L. [Also in Division H1] In an analytical gas chromatography process using at least two absorption columns the effluents from the columns are fed at least partly simultaneously into a common detector and recording device, the conditions of the columns being so adjusted that each peak may be recorded separtely without interference from another. The analysis conditions may be adjusted by starting at different times, having different flow rates for the carrier gas in each column or maintaining the columns at different temperatures. In analysing town gas, two columns are used, 16A containing silica gel followed by a 5Š molecular sieve for the separation of permanent gases, and 16B containing partially deactiviated silica gel for the separation of hydrocarbons. H 2  enters at 10 and flows via capillary flow meters 12A and 12B to sampling devices 13A and 13B. A sample of town gas is swept out of 13A into column 16A and the initial peaks registered in ionisation cross-section detector 18. After column 16A has been in operation for about 5 minutes, column 16B is also switched in and the separated components recorded using detector 18. A chromatograph is given (Fig. 4, not shown) which shows how the peaks do not interfere with each other. Detailed construction of the ionisation chamber is disclosed, (see Division H1). The detector 18 feeds its signal to a bridge network 25, an impedance converter 27 and a recorder 29, and details of the circuitry used are disclosed.
Patent GB-1054939-A (GB)
IPC: D06P1/673
Abstract: 1,054,939. Dyeing and cross-linking cellulose. K. H. TAUSS, A. B. HILTON, C. BEAUMONT and P. HARRIS. Nov. 14, 1963 [Nov. 15, 1962], No. 44982/63. Heading D1B. Cellulose materials are dyed and may also be simultaneously cross-linked by reacting them with a reactive dye in the presence of formaldehyde and a metallic salt which is a Lewis acid in the solid state. The cellulose materials may be impregnated with an aqueous solution, preferably of pH 5-9, containing the dye, formaldehyde and metallic salt, dyed and heated to effect the reaction, e.g. at 110-190‹C. The specified metallic salts are CaCl 2 , CaBr 2 , Cal 2 , Ca(NO 3 ) 2 , Ca(SCN) 2 , Mg(NO 3 ) 2  MgCl 2 , MgBr 2 , Mg(CLO 4 ) 2 , MgI 2 , SrCl 2 , Al 2 (SO 4 ) 3 , Zn(NO 3 ) 2 , CnSO 4  and BaCl 2 ; either the anhydrous salt or the hydrate or mixtures of salts may be used. Numerous known reactive dyes are listed. The treating solution may also contain NaCl or Na 2 SO 4  and may be applied by spraying or especially by padding. Since the dyed and cross-linked cellulose has a much lower dye-receptivity white or coloured resists may be put down. The specified cellulose materials are cotton and viscose. Examples are given. -
Patent GB-1087080-A (GB)
Abstract: 1,087,080. Recording-apparatus. GOERZ ELECTRIC G. m.b. H. April 14, 1966 (April 23, 1965], No. 16379/66. Heading G1J. A shaft 5 supporting a scriber 1 is bonded to the armature 7 of a relay 6 with the armature 7 held in its working position e. g. by exciting the relay 6 and with the shaft 5 rotated about its longitudinal axis to set the scriber 1 in position to record a line on a tape parallel to its direction of motion to represent a working condition. A cold-hardening bonding material 12 is used e. g. a plastics material, glue or solder. As shown twelve scribers can be held in position for attachment of their shafts 5 to appropriate armatures 7 by means of an abutment comb 4 which is movable from a position in which its teeth determine the rest positions of the scribers to a position in which they hold the scribers in their working positions. Bolts 10 passing through slots 3 in the comb 4 can lock it to the frame 13. In its rest position each scriber records a line parallel to that representing a working condition.
Patent GB-1095546-A (GB)
IPC: B29C45/14
Abstract: 1,095,546. Punching. STANDARD PRESSED STEEL CO. Dec. 10, 1964, No. 50387/64. Heading B3W. [Also in Divisions B5 and F2] Two apertures (6) are punched simultaneously in opposite sides of a nut (2) (Fig. 1, not shown) by means of a pair of punches 284 moved towards each other by downward movement of punch operating bars 286 having bevelled ends engaging corresponding ends of slide members 285 carrying the punches 284. The slide members 285 are biased outwardly by springs 288. The nuts are located in position by a centring pin 292. The bars 286 are mounted in a punch block 287 which is reciprocated vertically by an eccentric (not shown). The nuts are fed into punching position by a feed bar 306 which is movable to the right in Fig. 38 when a bevel ended bar 310 moves downwardly to engage the outer face 303 of a slide member 302. If a nut becomes jammed in the guideway 280 the bar 310 will pivot outwardly against the action of a spring 312 and operate a switch to stop the feed mechanism.
Patent GB-1097092-A (GB)
Abstract: 1,097,092. Photo-electric switches. SANGAMO WESTON Ltd. Jan. 28, 1965 [Feb. 4, 1964], No. 3843/65. Heading G1A. A non-contact-making rotary switch comprises a lamp 52, photo-diodes 24 arranged around the lamp and a baffle cylinder 54 therebetween. For half the circle round lamp 52, the diodes are in a first plane and for the other half in a second plane. The baffle cylinder, which is driven by a motor 58 has diametrically opposite apertures in each of the planes, the apertures of one plane being displaced from the other by half the angular spacing of adjacent diodes. As the cylinder 54 rotates the diodes, which are connected in individual circuits, are illuminated sequentially twice per revolution, to change the state of the corresponding circuit. A signal synchronized with the switching may be derived from a 3-phase generator 76. In a modification the diodes may be arranged in three or more planes.
Patent GB-1130084-A (GB)
Abstract: 1,130,084. Pipe couplings. CAJON CO. 20 April, 1966 [11 Aug., 1965], No. 17206/66. Heading F2G. A nut 20 screwed on to an extension 12 of a fitting 10 has an internal flange which abuts a bush 31 and causes the latter to axially compress an 0-ring 30 so that the ring is expanded radially inwardly into sealing engagement with a tube 14; the bush is stepped as shown and the flange 33 thereof may be brought into abutment with the fitting.
Patent GB-1227126-A (GB)
IPC: F02M69/08
Filed: 1968-04-11
Abstract: 1,227,126. Spray carburetters and fuel injectors. G. GIANINI. April 11, 1968 [May 5, 1967], No.17563/68. Heading F1B. Fuel, supplied continuously under pressure to a collecting chamber 4, is blown therefrom intermittently by pulses of air or gas supplied to a pipe 9, whereby the fuel is atomized and discharged into an intake pipe 1 or directly into the cylinder. The gas may be supplied to pipe 9 from a pump through a distributer, the pulses being timed to arrive at chamber 4 just before or during the intake phase of a cylinder; alternatively the gas pulses may be obtained from the exhaust pipe. The fuel is supplied under pressure by a pump 7, the supply being maintained proportional to the air supply by a bleed-off system 8 having a suction operated bypass valve or a valve controlled directly by throttle valve position. In Fig. 2 (not shown) the fuel nozzle discharges into a small venturi (15). A plurality of carburetters may be provided one for each cylinder, discharging into a common intake pipe.
Patent GB-1228014-A (GB)
IPC: C02F1/06
Filed: 1968-06-25
Abstract: 1,228,014. Evaporators, flash type; desalination of sea water. NORTH AMERICAN ROCKWELL CORP. 25 June, 1968 [26 June, 1967], No. 30300/68. Heading B1B. Liquor, e.g. sea water, is distilled by passing a heated stream of the liquor 66 (Fig. 4) through a chamber wherein flash vaporization of some of the liquor takes place, and contacting the flashed vapour 74 with a stream of cooled distillate 56 flowing over a stacked arrangement of trays 42 which cause the vapour to flow in a tortuous path of decreasing cross-sectional area. The vapour passes through demisters 76, 78 before it flows over, and condenses on, the surface of the distillate in trays 42. Figs. 2 and 3 show an inclined distillation unit divided into stages 44 by barrier walls 64. Sea water at a temperature of e.g. 200F. is pumped through conduit 16 into the lower end of the unit and passes up through successive stages via submerged orifices 68 in the barrier walls 64. Sea water flows out at the upper end of the unit into receptacle 50. Fresh water at a temperature of e.g. 67F enters the upper end of the unit through conduit 14 and flows down over the trays 42 in stages of decreasing height via orifices 62 in the barrier walls 64. The distillate flows out of the lowest stage into receptacle 52. Air passes through ports 90 at the tops of the barrier walls and is exhausted from the unit through conduit 36 which is connected to a vacuum system. A portion of the sea water, withdrawn from receptacle 50, is discharged from the system, and the remainder is mixed with sea water feed and passed in heat-exchange with the distillate withdrawn from receptacle 52. The sea water then passes through a heater and enters the lower end of the distillation unit. The distillate flowing out of the heat exchanger is further cooled in heat exchange with the sea water feed. A portion of the cooled distillate is withdrawn from the system, and the remainder is recirculated to the upper end of the distillation unit. The trays 42 may be perforated.
Patent GB-1229209-A (GB)
IPC: H01S3/10
Filed: 1967-12-07
Abstract: 1,229,209. High speed camera. MINISTER OF TECHNOLOGY. Nov. 29, 1968 [Dec. 7, 1967], No. 55625/67. Heading G2E. A rotating mirror high speed camera comprises a length of film 11 in cylindrical form around a central axis, a plurality of inwardly facing plane mirrors 13 arranged around the central axis, a lens system including a scanning mirror 14 and a transfer lens 15 arranged to be rotatable together about the said axis and arranged so that image forming light directed along said axis is thrown by the scanning mirror 14 on to a succession of the plane mirrors 13 and thence through the transfer lens 15 to form a succession of images on the film. The angular setting of the mirrors 13 on their supports is adjustable, Figs. 3 and 4 (not shown), and a prism 17 is provided which rotates about the axis of the system at half the speed of the scanning mirror 14 to compensate for rotation of the image in its own plane. A small image translation caused by rotation of the nodal points of lens 15 is minimized by positioning primary image 26 slightly away from mirror 14.
Patent GB-1230214-A (GB)
IPC: C22B26/22
Filed: 1968-09-18
Abstract: 1,230,214. MgO and K 2 SO 4  from kainite. NATIONAL LEAD CO. 18 Sept., 1968 [18 Sept., 1967], No. 44270/68. Heading C1A. Potassium sulphate and kainite are obtained by heating kainite, MgSO 4 .KC1.3H 2 O at 500 to 900 C. in the presence of steam and a carbonaceous reducing agent in an amount at least equal to that stoichiometric amount required to reduce the kainite to K 2 SO 4  and MgO until a calcinate is obtained consisting of K 2 SO 4  and MgO, water slurrying the calcinate to dissolve the K 2 SO 4 , separating the MgO precipitate and concentrating the resulting solution to precipitate K 2 SO 4 . The carbon is suitably in the form of particles added to the slurry of salts or introduced as a blown stream during the roasting operation. Excess carbon carried over to the MgO filter cake can be removed by reroasting or on conversion of the oxide to the chloride.
Patent GB-1231070-A (GB)
IPC: B64D17/32
Filed: 1968-06-06
Abstract: 1,231,070. Releasable fastenings. J. MARTIN. 28 May, 1969 [6 June, 1968], No. 27064/ 68. Heading E2A. A releasable latch mechanism comprises a first part 1 having a bore 2 in which a tubular portion 20 of a second part lies, the first part being adapted to be coupled to a cord, cable, wire or rod (shown as a slotted cable) extending through said tubular portion, a lever 7 being pivotally coupled to said first part and movable towards said bore and tubular portion, said lever pivotally carrying an abutment 14 having first and second abutment parts 18, 17, said abutment being biassed into a position in which the first abutment part 18 engages a detent 12 in said tubular portion of the second part whilst the second abutment part 17 engages said first part so that movement of the tubular portion along said bore in one direction is normally prevented, movement of said lever from an inoperative position in a direction towards said first part causes angular movement of the abutment and disengagement of said abutment 14 from said tubular portion thereby permitting movement to occur in said one direction along the bore of the first part, means 23 being provided on said second part to enable movement of the second part with said first part to be prevented. In the construction shown there are two of said levers and two of said abutments disposed symmetrically and the abutments are biassed by springs 16 disposed between the abutments and the levers; these springs also bias the levers to their inoperative positions but this is assisted by additional springs 12. The second parts 17 of the abutments pass through apertures 4 to engage the detent 22 in the form of a groove in the tubular part 20.
Patent GB-1239326-A (GB)
IPC: A43D25/18
Filed: 1969-08-04
Abstract: 1,239,326. Boots &c. ZAVODY PRESNEHO STROJIRENSTVI NARODNI PODNIK. 4 Aug., 1969 [13 Sept., 1968], No. 38931/69. Heading A3B.  A wiper actuating mechanism for a lasting machine having interchangeable wipers 21, 21<SP>1</SP>, has a piston and cylinder device 1, 2 which has its piston rod connected by a rocker lever 3 and two links 4 to two cross levers 6, 6<SP>1</SP> which are pivoted to the machine frame by pins 9, 9<SP>1</SP>. The levers 6, 6<SP>1</SP> have registering slots 10 in which slides a pin 11<SP>1</SP> which is fixed to a push rod 12 which is connected by pin 13 to the wiper head 14. Thus operation of the piston and cylinder 1, 2 causes forward movement of the wiper head 14. The ends of the levers 6, 6<SP>1</SP> are connected by adjustable push rods 17, 17<SP>1</SP> to the wiper holders 15, 15<SP>1</SP> which are movable along circular tracks in the wiper head 14. Thus operation of the piston and cylinder 1, 2 causes the push rods 17, 17<SP>1</SP> to move forwardly at a faster rate than the wiper head 14 so that the wipers 21, 21<SP>1</SP> perform a circular closing movement. The wipers 21, 21<SP>1</SP> are interchangeably mounted in the holders 15, 15<SP>1</SP> by pins 24 in wipers engaging holes 25 in the holders 15, 15<SP>1</SP> and by removable pins 23 which pass through holes 23<SP>1</SP> in the wipers 21, 21<SP>1</SP> and holders 15, 15<SP>1</SP>. The machine also includes an insole hold-down 33 which is pivoted by pin 35 to one end of a lever 36. The other end of the lever 36 has a roller 39 which contacts slide cam 40 which is moved by piston and cylinder 43, 44. When the wipers have completed their operation the slide cam 40 is moved to raise the hold-down 33 so that the shoe support can exert full bedding pressure against the wipers.
Patent GB-1252895-A (GB)
IPC: F16F1/36
Filed: 1968-12-03
Abstract: 1,252,895. Vibration damping laminated systems. FARBWERKE HOECHST A.G. 3 Dec., 1968 [5 Dec., 1967], No. 57350/68. Heading B5N. [Also in Divisions B2 and C3] A vibration damping laminated system comprises two plates, e.g. of metal such as steel, bonded together with an interlayer comprising a graft polymer of 55-90% by weight of an equimolar mixture of styrene and acrylonitrile on 45-10% by weight of a copolymer of 30-- 50% by weight of vinyl acetate and 50-70% by weight of ethylene. The graft polymer may contain minor amounts of fillers, e.g. heavy spar, silicic acid, graphite, soot or a mixture thereof, and one or more plasticizers. The total thickness of the laminated system may be 1-6 mm., the thickness of the interlayer being 0À1-1 mm. and the ratio of the thicknesses of the plates being from 1 : 1 to 4 : 1. The graft polymer may be applied to the plates by trowelling, brushing or pouring at elevated temperature and the system cooled under pressure between rollers. A gel of the copolymer in the styrene/acrylonitrile mixture to be grafted on which contains a polymerization initiator, e.g. tertiary butyl hydroperoxide, may be applied between the plates and the laminated system subjected to heating at 60-180 C. to effect grafting.