baber/WOPTO huggingface dataset:
Patent DE-69508890-D1 (DE)
Inventor: MICLO LAURENT
IPC: C07K14/47
Filed: 1995-11-30
Granted: 1999-05-12
Abstract: Pharmaceutical compsns. contg. the decapeptide of formula (I) are new: Tyr-Leu-Gly-Tyr-Leu-Glu-Gln-Leu-Leu-Arg (I). Also claimed are food prods. contg. (I), or a (I)-contg. total tryptic hydrolysate of casein  alpha  s1 or a (I)-contg. fraction of such a hydrolysate (esp. in combination with an edible protein or carbohydrate carrier in a food supplement) .
Patent DE-69513279-D1 (DE)
Inventor: HEERES JAN
IPC: A61K31/36
Filed: 1995-01-17
Granted: 1999-12-16
Abstract: PCT No. PCT/EP95/00174 Sec. 371 Date Jun. 20, 1996 Sec. 102(e) Date Jun. 20, 1996 PCT Filed Jan. 17, 1995 PCT Pub. No. WO95/19983 PCT Pub. Date Jul. 27, 1995A compound of formula (I),    <IMAGE>  (I)  or a stereochemically isomeric form thereof, wherein A and B taken together form -N=CH-, -CH=N-, -CH2-CH2, CH=CH-, -C(=O)-CH2-, -CH2-C(=O); D is a radical of formula    <IMAGE>  (D1)   <IMAGE>  (D2) GE>  (L1)   <IMAGE>  (L2)  Alk is a C1-4alkanediyl radical; R1 is halo; R2 is hydrogen or halo; R3 is hydrogen, C1-6alkyl, phenyl or halophenyl; R4 is hydrogen, C1-6alkyl, phenyl or halophenyl; R5 is hydrogen or C1-6alkyl; R6 is hydrogen, C1-6alkyl, C1-6alkyloxycarbonyl, or R5 and R6 taken together with the nitrogen atom to which they are attached form a heterocyclic ring. Active intermediates, compositions and methods of preparing compounds, compositions are described.
Patent DE-69513395-D1 (DE)
Inventor: AGRAWAL SUDHIR
IPC: A61K47/48
Filed: 1995-06-01
Granted: 1999-12-23
Abstract: Disclosed is a composition including an oligonucleotide complexed with a cyclodextrin. The oligonucleotide may be noncovalently associated with the cyclodextrin. Alternatively, the oligonucleotide may be covalently complexed with adamantane which is noncovalently associated with the cyclodextrin. Also disclosed are methods of enhancing the cellular uptake and intracellular concentration of oligonucleotides, methods of increasing the solubility of an oligonucleotide in a cell, and methods of treating a cell for viral infection or to prevent viral infection.
Patent DE-69519746-D1 (DE)
Inventor: COHEN ERIC A
IPC: A61K38/00
Filed: 1995-09-07
Granted: 2001-02-01
Abstract: The present invention relates to a Vpr protein, a Vpx protein or fragments thereof which permit the development of chimeric molecules that can be specifically targeted into the mature HIV-1 and HIV-2 virions to affect their structural organization and/or functional integrity, thereby resulting in gene therapy for HIV-1 and HIV-2 infections. The present invention also relates to Vpr/Vpx protein Fragments, p6 protein, p6 protein fragment, or functional derivatives thereof which interfere with the native Vpr/Vpx incorporation into HIV-1 and HIV-2 virions. The present invention also relates to treatment of HIV-1 and HIV-2 infections based on the proteins of the present invention.
Patent DE-69523705-D1 (DE)
Inventor: MARINUS HARRY
IPC: G06F11/30
Filed: 1995-03-17
Granted: 2001-12-13
Abstract: A system comprising a microprocessor and a reset and watchdog circuit. The microprocessor generates a first pulse train (P1) to indicate the correct operation of the microprocessor and the reset and watchdog circuit generates a reset signal (RST) in response to an irregularity in the occurrence of the first pulse train. The first pulse train is a substantially synchronous software copy of a second pulse train (P2) which is received by the microprocessor and which is preferably a limited a.c. supply voltage signal. This copy is generated by an appropriate programming of the microprocessor. The reset and watchdog circuit receives the first pulse train (P1) and the second pulse train (P2) and supplies the reset signal (RST) in response to a disturbed synchronism between the occurrence of the first pulse train and the second pulse train.
Patent DE-69529347-D1 (DE)
Inventor: HU ZHICHENG
IPC: B01D53/94
Filed: 1995-09-12
Granted: 2003-02-13
Abstract: A stable, close-coupled catalyst, an article comprising the close-coupled catalyst and a related method of operation. The close-coupled catalyst comprises a catalyst support and a palladium catalytic component. Preferably and optionally, there are stabilizers including alkaline metal oxide, and rare earth metal components selected from the neodymium and lanthanum components. The close-coupled catalyst composition includes substantially no additional oxygen storage component such as praseodymium or cerium compounds. There is preferably a catalyst such as a three-way catalyst downstream of the close-coupled catalyst. The downstream catalyst preferably includes an oxygen storage component such as cerium oxide or praseodymium oxide.
Patent DE-69534472-D1 (DE)
IPC: C12N15/11
Filed: 1995-06-29
Granted: 2006-02-02
Abstract: Nucleic acid molecules and proteins useful for regulating the expression of genes in eukaryotic cells and organisms are disclosed. The invention provides a transcriptional activator fusion protein which binds to tet operator sequences and stimulates transcription of a tet operator-linked gene in the presence, but not the absence, of tetracycline (or analogue thereof). The invention further provides transcriptional inhibitor fusion proteins which inhibit transcription of a tet operator-linked gene in a regulated manner. In one embodiment, the inhibitor fusion protein binds to tet operator sequences in the absence, but not the presence, of tetracycline (or analogue). In another embodiment, the inhibitor fusion protein binds to tet operator sequences in the presence, but not the absence, of tetracycline (or analogue). The transcriptional activator and inhibitor fusion proteins of the invention can be used in combination to regulate expression of one or multiple tet operator-linked genes. Novel tet operator-containing transcription units which allow for coordinate or independent tetracycline-regulated expression of two or more genes by the transcriptional modulators of the invention are also disclosed. Kits including the components of the regulatory system are also encompassed by the invention. <IMAGE>
Patent DE-69607340-D1 (DE)
Inventor: SABATIER DENIS
IPC: B65D5/20
Filed: 1996-04-25
Granted: 2000-04-27
Abstract: The invention relates to a punched blank for a tray-like package. It comprises a bottom part (1), two long sides (2) and two short sides (3) in one piece with the bottom part (1) and marked with respect to this by fold lines (6, 7). The long and short sides (2, 3) are intended to be folded up and united with each other at the ends. The invention is characterized in that the fold lines (7) between the bottom part (1) and at least the long sides (2) are directed inwardly at the ends and form an angle between the middle part (6) of the fold lines of 2-20 DEG .
Patent DE-69610773-D1 (DE)
Inventor: HEKMAT RAMIN
IPC: H04B7/26
Filed: 1996-07-23
Granted: 2000-11-30
Abstract: Prior art telecommunication systems, having per cell a base station and a few repeaters, are inefficiently composed. By making use of a new cell structure, in which a cell consists of three hexagonal and equilateral sub-cells possessing one common point at the place where the base station is situated, having per sub-cell a repeater centrally situated in the sub-cell, a telecommunication system is obtained which is very efficiently composed as far as distribution in space is concerned, and by dividing a sub-cell into three equal sectors and providing it with an extra repeater, a telecommunication system is obtained which is very efficiently composed as far as time division is concerned, on account of the fact that loss of usable time slots, present due to application of a first repeater, is compensated for by application of a second repeater, in which the loss of usable time slots, present due to application of the second repeater, is compensated for by application of the first repeater. Both repeaters are in this case, for example, so-called alternating slot repeaters.
Patent DE-69620219-D1 (DE)
Inventor: HOLDAWAY R
IPC: H02P8/04
Filed: 1996-09-11
Granted: 2002-05-02
Abstract: A motor control system that reduces noise while reducing power requirements but providing sufficient torque. A one-phase-on drive mode modified to microstep between "one phase on" positions is used to accelerate the motor in a non-linear manner to a maximum speed. The microstep drive modes have a constant period, and the step rate of the motor is increased by decreasing the number of microsteps in succeeding steps of the motor. A modified full step waveform maintains the motor at the maximum speed, where the current to one winding of the step motor changes polarity within one motor step while the other remains approximately constant providing increased smoothness in the drive and reduced noise. The polarity changes in accordance with the inductance and the compliance voltage of the motor. A one-phase-on waveform modified to include microsteps between "one phase on" positions later decelerates the motor in a non-linear manner, and the motor stops in a detent position until another waveform of steps in delivered to the motor. <IMAGE>
Patent DE-69631335-D1 (DE)
Inventor: TOCQUE BRUNO
IPC: C12N15/09
Filed: 1996-09-02
Granted: 2004-02-19
Abstract: The present invention relates to the utilization of a compound capable of antagonizing at least partially the oncogenic activity of the protein Mdm2 for the preparation of a pharmaceutical composition intended more particularly to a treatment of cancers with no p53 context. It further relates to the viral vector comprising a nucleic acid sequence coding for a compound capable of inhibiting at least partially the oncogenic activity of the protein Mdm2, and to a corresponding pharmaceutical composition.
Patent DE-69631882-D1 (DE)
Inventor: VENKATESHWARAN N
IPC: A23L1/00
Filed: 1996-05-10
Granted: 2004-04-22
Abstract: Oxygen-scavenging compositions comprising an oxidizable metal component, an electrolyte component and a solid, non-electrolytic, acidifying component and, optionally, a water-absorbant binder and/or a polymeric resin exhibit good oxygen-scavenging performance with improved oxidation efficiency relative to compositions containing oxidizable metal component and either an electrolyte or acidifying component but not both. The compositions can be used as an oxygen absorbent in packets or in combination with thermoplastic resins melt-fabricated into a wide variety of oxygen-scavenging packaging articles.
Patent DE-69632531-D1 (DE)
Inventor: BADWAL P
IPC: H01M8/124
Filed: 1996-03-15
Granted: 2004-06-24
Abstract: PCT No. PCT/AU96/00140 Sec. 371 Date Nov. 25, 1997 Sec. 102(e) Date Nov. 25, 1997 PCT Filed Mar. 15, 1996 PCT Pub. No. WO96/28855 PCT Pub. Date Sep. 19, 1996An electrical interconnect device for a planar fuel cell, comprising solid oxide electrolyte (44), an anode and a cathode (42), is described. The interconnect device comprises a plate-like chromium-containing substrate (22) having gas-flow channels (28) on the cathode-side and a coating on the cathode-side. The coating comprises an oxide surface layer comprising at least one metal M selected from Mn, Fe, Co and Ni, and an M, Cr spinel layer intermediate the substrate and the oxide surface layer. The intermediate spinel layer is formed by reaction of M oxide with surface chromium oxide on the substrate. The coating material may be applied as oxide or as salt or metal, or a mixture, and then converted to oxide. The M-metal(s) may be mixed with non-M metal or be doped. Methods of application are described in which the oxide surface layer is partially reacted to form the intermediate spinel layer.
Patent DE-69635979-D1 (DE)
Inventor: DOYLE JOHN MARTIN
IPC: G01N33/573
Filed: 1996-02-02
Granted: 2006-05-18
Abstract: Determining the hepatic status of a subject, comprises: (a) measuring the level of the ~p glutathione S-transferase (~pGST) isoform in a sample of a biological fluid from the subject by an immunoassay specific for the ~pGST isoform; (b) comparing the level of ~pGST measured with the normal range of ~pGST in the biological fluid, and when an increase in the ~pGST relative to the normal range is detected, (c) determining the hepatic status of the subject based on the level of ~pGST in the biological fluid. Kits for carrying out the above method are also included within the scope of the invention.
Patent DE-69702705-D1 (DE)
Inventor: HUDKINS L
IPC: A61P25/00
Filed: 1997-02-20
Granted: 2000-09-07
Abstract: Disclosed in this patent document are synthetic, biologically active molecules referred to as fused pyrrolo[2,3-c]carbazole-6-ones. These molecules are represented by the following general formulae:   using the fused pyrrolo[2,3-c]carbazole-6-ones are also disclosed.
Patent DE-69715821-D1 (DE)
Inventor: TANDART JEAN-MARIE
IPC: B21D39/08
Filed: 1997-05-12
Granted: 2002-10-31
Abstract: The expander comprises a tool which is basically cylindrical in shape and made up of a series of sector-shaped jaws (3), e.g. six in number, which are moved apart to expand the end of a pipe by means of a conical pin (15) inserted axially between them. After the pin has been retracted the jaws are returned to their initial, closed positions by internal springs. Each of the jaws has flat surfaces adjacent to its lateral faces, so that each of its outer corners is right-angled in shape.
Patent DE-69728453-D1 (DE)
Inventor: FREED S
IPC: A61M37/00
Filed: 1997-12-22
Granted: 2004-05-06
Abstract: A percutaneous access device implantable beneath the skin of a patient which includes a housing having a flange positionable beneath the skin and neck projecting outward through the skin. The percutaneous access device includes electrical communication through the flange and fluid access through the flange. The components providing fluid access and electrical communication are removable through the neck portion of the implant for testing and service as required without the need for further surgery on the patient. A turret body is received within the hollow interior of the neck having a fluid channel extending therethrough and containing current limiting devices securely disposed within the turret body.
Patent DE-69733017-D1 (DE)
Inventor: SCHMID CHRISTIAN
IPC: B29C48/78
Filed: 1997-05-16
Granted: 2005-05-19
Abstract: Solid extrusion coating compositions for metal substrates, a method of extrusion coating a metal substrate, and a metal article are disclosed. The extrusion coating composition is a thermoplastic material and comprises: (a) a polyester having a weight average molecular weight of about 10,000 to about 50,000, and optionally, (b) a modifying resin, such as an epoxy resin having an epoxy equivalent weight of about 500 to about 15,000. The extrusion coating composition is applied to a metal substrate in an extrusion process to provide a composition film having a thickness of about 1 to about 40 microns. <IMAGE>
Patent DE-69734802-D1 (DE)
Inventor: KANOMI RYUZO
IPC: A61C8/00
Filed: 1997-08-08
Granted: 2006-01-12
Abstract: The present invention provides a supporting body for use in an orthodontic appliance capable of applying a force to the tooth to be treated from the most preferable position. The supporting body includes an implant member having the maximum dimension in its cross section of 2mm or less for being implanted in a jaw bone (maxilla and/or mandibula), and an exposed member forming one end of the supporting body to be exposed to inside of mouth. The exposed portion includes an extended arm and the arm is formed with a hook. <IMAGE>
Patent DE-69735707-D1 (DE)
Inventor: LEFEBVRE PASCAL ALBERT EMILE
IPC: H04Q11/04
Filed: 1997-05-26
Granted: 2006-05-24
Abstract: A method for prioritised data transmission to a common transmission medium from a plurality of interface modules coupled to it, for interfacing at least one input bitstream with said common transmission medium, whereby access is arbitrated on the basis of a module priority of each interface module, is such that, for at least one interface module, the module priority is dependent on at least one connection parameter associated to packets of said at least one input bitstream. An arrangement for performing this method is described as well as several variant implementations of the method and the arrangement. <IMAGE>
Patent DE-69739059-D1 (DE)
Inventor: SCHULZE-LEFERT PAUL MARIA
IPC: C12N15/82
Filed: 1997-07-29
Granted: 2008-12-04
Abstract: The present invention relates to stimulating a defense response in plants, with a view to providing the plants with enhance pathogen resistance.
Patent DE-69739721-D1 (DE)
Inventor: TRANI GIORGIO
IPC: D21H19/22
Filed: 1997-01-20
Granted: 2010-02-11
Abstract: A paper material for forming soft three-dimensional packaging containers, characterised by consisting of a yieldable paper sheet (4) to which at least one impermeabilizing agent has been added.
Patent DE-69800324-D1 (DE)
Inventor: POLE ANDREW
IPC: A22B5/00
Filed: 1998-03-20
Granted: 2000-11-02
Abstract: A band saw comprising an endless band (5) mounted to a support (4) for cyclic movement along a continuously curved, oval path. The support (6) is constructed such that part of material being cut can pass through a region (13) defined within the path of the blade (5). Means are provided for driving the blade. <IMAGE>
Patent DE-69801424-D1 (DE)
Inventor: DE VRIES CORNELIS
IPC: B01D53/70
Filed: 1998-03-17
Granted: 2001-09-27
Abstract: A process for the removal of contaminants from a gas, using a gas cleaning agent, which contamination is selected from the group comprising aromatic hydrocarbons and (poly)halogenated aromatic hydrocarbons. For the removal of the contaminant a detergent is added as gas cleaning agent. The detergent is selected from a group formed by an anionic detergent, non-ionic detergent and a mixture thereof.
Patent DE-69808349-D1 (DE)
Inventor: JUNGHANS ANDREAS
IPC: G06F13/40
Filed: 1998-02-20
Granted: 2002-11-07
Abstract: An apparatus and method which overcomes connectivity limitations on PCMCIA and PC-CARD95 compatible devices by reconfiguring standard PCMCIA and PC-CARD pins for additional electrical interfaces. A detection circuit in the PC-card can detect the different interfaces. Once the different interfaces are identified, the connections to the receptacles of the PC-card connector are reconfigured such that the functional assignments of the receptacles conform with the requirements of each different interface. Thus, connection between different electrical interfaces to the physical interface of a PCMCIA-compatible device, without interference between them is possible. This eliminates the need for extra connectors other than the standard PCMCIA and PC-CARD95 connector. Thus, more versatile products with enhanced connectivity may be designed which use the PCMCIA and PC-CARD95 standards. <IMAGE>
Patent DE-69809763-D1 (DE)
Inventor: VALENTINSSON ANDERS
IPC: B29C49/48
Filed: 1998-02-27
Granted: 2003-01-09
Abstract: Article made of thermoplastic material, which article is rigid and at least partly heat insulating. The article includes a laminate in at least parts of the article. The laminate includes a first and a second layer of solid thermoplastic material (A) and an intermediate layer of expanded thermoplastic material (B) with an average density of 50-800 kg/m3. The thermoplastic materials (A) and (B) are the same or compatible materials. The article is manufactured according to a process comprising the steps a) forming of a solid outer layer, b) manufacturing of an intermediate expanded layer and c) the appendage of functional parts such as reinforcing profiles, guiding profiles, stacking profiles, hinge parts, pockets, label holders, profiles or holes for automatic handling, locking devices or the like.
Patent DE-69811680-D1 (DE)
Inventor: HATSUSHIBA KIYONORI
IPC: A61K51/02
Filed: 1998-08-13
Granted: 2003-04-03
Abstract: A stable radioctive medicine which comprises a radioactive iodine-labeled compound and a deiodination inhibitor selected from the group consisting of  alpha -thioglycerol, sodium hydrogensulfite, sodium pyrosulfite, cysteine hydrochloride, sodium edetate, sodium thioglycolate, and butylhydroxyanisol. This medecine stably retains the radioactive iodine incorporated in the radioactive iodine-labeled compound and undergoes no decrease in radiochemical purity. It is hence extremly useful in the field of radiotherapy.
Patent DE-69903181-D1 (DE)
Inventor: URICH KLAUS
IPC: A61M1/02
Filed: 1999-08-26
Granted: 2002-10-31
Abstract: A syringe for use with an injector includes a body comprising a distal discharge end, a plunger movably disposed within the body, and an agitation element disposed within the body between the plunger and the distal discharge end. The agitation element is acted on by a magnetic field to agitate the contents of the syringe. The magnetic field is generated by a source operably associated with the syringe or the injector. Preferably, the syringe contains an ultrasound contrast agent that is agitated by the agitation element. An injector system and a method for agitating the contents of a syringe are also provided.
Patent DE-69905562-D1 (DE)
Inventor: MELOCCHI MARIO
IPC: F21Y101/00
Filed: 1999-04-22
Granted: 2003-04-03
Abstract: A connector of the insulation-perforating type for a suspended electrical system comprises conductive means for cutting an insulating covering of an insulated supply cable in order to connect an electrical device electrically to an uncovered portion of the supply cable, and an insulating structure for enclosing the conductive means, in which the insulating structure includes a first insulating element which can be closed around the supply cable in a non-reversible manner in order to protect the uncovered portion from manual contact, and a second insulating element which can be connected to the electrical device and which can be joined reversibly to the first insulating element, the first insulating element comprising means for preventing sliding along the supply cable.
Patent DE-69907125-D1 (DE)
Inventor: CAMIN DANIEL VICTOR
IPC: G01R19/00
Filed: 1999-12-15
Granted: 2003-05-28
Abstract: There is described a direct current meter with passive input and galvanic insulation, particularly for high voltage. The direct current meter is made up of a passive input part (1) and of an active output part (2) that is optically coupled to the passive part (1) and electrically insulated from it. In this way the high voltage present at the input only affects the passive part of the meter, whereas the active part can be supplied with a low voltage and can be made capable to provide an output signal proportional to the current to be measured and substantially independent from the working temperature. <IMAGE>
Patent DE-69909311-D1 (DE)
Inventor: SHUTTER A
IPC: H01R13/66
Filed: 1999-04-27
Granted: 2003-08-07
Abstract: A multi-piece, low profile microelectronic connector having a simplified, "snap-together" construction requiring no lead carrier. One or more electrical components are located within a rear connector body element, which mates with a front connector body element upon assembly. The leads of the rear body element are shaped so as to cooperate with a series of contour elements ("bumps" in one embodiment) formed inside the plug receptacle cavity in the front connector body element. The shape of the leads and bumps provide a continuous normal force on the distal end of the leads, thereby maintaining them in contact with the corresponding leads of the modular plug. In a second aspect of the invention, a series of mounting pins are provided to permit tandem mounting of multiple connectors to an external device using a minimum number of mounting holes, and maintaining a minimum lateral connector width. A method of manufacturing and assembling the aforementioned connector is also disclosed.