baber/WOPTO huggingface dataset:
Patent EP-0862630-B1 (EP)
Inventor: BLACK AMELIA
IPC: C07K16/46
Filed: 1996-11-07
Granted: 2007-06-13
Abstract: The present invention is directed to humanized antibodies which bind human gp39 and their use as therapeutic agents. These humanized antibodies are especially useful for treatment of autoimmune diseases.
Patent EP-0794794-B1 (EP)
Inventor: BRODER SAMUEL
IPC: A61K38/13
Filed: 1996-10-24
Granted: 2005-12-07
Abstract: A method of increasing the bioavailability upon oral administration of a pharmacologically active target agent, particularly an antitumor or antineoplastic agent which exhibits poor or inconsistent oral bioavailability (e.g., paclitaxel, docetaxel or etoposide), comprises the oral co-administration to a mammalian patient of the target agent and an oral bioavailability-enhancing agent (e.g., cyclosporin A, cyclosporin D, cyclosporin F or ketoconazole). The enhancing agent may be administered orally from 0.5-24 hrs. prior to the oral administration of one or more doses of the target agent, substantially simultaneously with the target agent or both prior to and substantially simultaneously with the target agent. A method of treating mammalian patients suffering from diseases responsive to target agents with poor oral bioavailability, as well as oral dosage forms containing such target agents, combination oral dosage forms containing bioavailability-enhancing agents and target agents and kits containing enhancing and target agent dosage forms and dosing information for the co-administration of the same are also disclosed.
Patent EP-0870049-B1 (EP)
Inventor: KOVESDI IMRE
IPC: A61K39/00
Filed: 1996-12-12
Granted: 2006-03-15
Abstract: The present invention provides multiply replication deficient adenoviral vectors having a spacer in at least one replication deficient adenoviral region, as well as complementing cell lines therefor. Also provided are means of constructing the multiply replication deficient adenoviral vectors and methods of use thereof, e.g., in gene therapy.
Patent EP-0796710-B1 (EP)
Inventor: SAUTNER KARL-HEINZ
IPC: B09B3/00
Filed: 1997-03-18
Granted: 2002-06-12
Abstract: When obtaining a starting product(10) for the production of heat insulation elements: a) the cells of scrap polyurethane foam are opened up, but retain part of their structure; b) the gas is removed and the open cellular particles classified according to size c) particles of a medium size(6) are separated off for use as a starting material. Process equipment includes machinery for opening up the foam cells, a separator(3) for removing gas from the open cellular particles, a classifying device for separating the particles into at least three sizes(5,6,7) and a collector for particles of the medium size(6).
Patent EP-0818421-B1 (EP)
Inventor: KOSLOWSKY PETER
IPC: C02F1/66
Filed: 1997-07-04
Granted: 1999-08-04
Abstract: A process for treating and purifying water for swimming pools uses water softeners, filters, pumps and pipes for circulating water. The water is treated with ion exchangers (6) to remove acids and water hardness components and the softened water is used to fill a pool (1). Lime water (8), comprising a clear saturated solution of (hydrated) lime in water, is added to the pool to create a lime-carbonic acid equilibrium which converts any carbon dioxide in the water into carbonate in order to precipitate phosphate and sulphate as sparingly soluble calcium salts, as well precipitating body substances (eg. dead skin), creams and bath oils as lime soaps. Inorganic oxidation products generated by sunlight are precipitated as calcium ions, and small suspension or sediment solids not normally capable of being filtered are adsorbed onto calcite. The water is passed continuously through a cycle consisting of pipes (13, 19, 20) , pumps (17), valves (14, 18) and filters, forcing at least some of the water to flow a bed of crushed limestone to keep pH above 7. More limewater is optionally added to maintain the lime-carbonic acid equilibrium. Lost water is replenished with fresh acid- and hardness-free water to prevent water in the pool becoming too salty. The apparatus is also claimed.
Patent EP-0827962-B1 (EP)
Inventor: DEVORE DAVID D
IPC: C25B3/23
Filed: 1995-07-06
Granted: 2001-01-10
Abstract: Silylium salts corresponding to the formula: R3Si(X')q<+>A<-> wherein     R independently each occurrence is selected from hydrocarbyl, silyl, hydrocarbyloxy, dihydrocarbylamino, and combinations thereof having up to 30 nonhydrogen atoms, X' is an optional Lewis base having up to 20 nonhydrogen atoms, q is 0 or 1, and   A<-> is a noncoordinating, compatible anion, are prepared by oxidizing, preferably electrolytically, a solution comprising a disilane compound corresponding to the formula: R3SiSiR3 wherein R is as previously defined, in the presence of a source of the noncoordinating counter ion, A<->.
Patent EP-0842879-B1 (EP)
Inventor: COLOMBO EZIO
IPC: B65G57/18
Filed: 1997-10-08
Granted: 2001-02-28
Abstract: A rotary electromagnetic head for automatic stackers of iron sections originating from a rolling mill comprises an expulsion device provided with a bar (13) rotating together with the head (10) but also provided with simultaneous movement relative to the head (10). Said relative movement is caused by a cam (15) against the action of a counteracting spring (20). <IMAGE>
Patent EP-0886640-B1 (EP)
Inventor: OEHRLEIN REINHOLD
IPC: C07H3/06
Filed: 1997-01-17
Granted: 2007-03-21
Abstract: Sialyl-Lewisx and sialyl-Lewisa epitope analogues in which the naturally occurring N-acetyl group of the N-acetylglucosamine monomer is replaced by various aliphatic or aromatic substituents and the L-fucose naturally present is replaced by various naturally occurring or non-naturally occurring sugars.
Patent EP-0883576-B1 (EP)
Inventor: STIGEBRANDT AKE
IPC: C02F11/128
Filed: 1997-02-26
Granted: 2002-07-31
Abstract: A dewatering device for batch-wise separation of liquid from particle-laden sludge, exhibiting the characteristic features comprising a closed, downwards openable container having a liquid-pervious wall, and an inlet pipe which is connected to the container for infeed of sludge to said container.
Patent EP-0835667-B1 (EP)
Inventor: UCHIDA TAKANORI
IPC: A61L24/10
Filed: 1997-03-14
Granted: 2005-11-09
Abstract: An adhesive for tissue capable of uniformly forming a high concentration of fibrin so as to provide a high closing effect is disclosed. The adhesive for tissue comprises a fibrinogen solution and a thrombin solution which solutions are separated from each other. The adhesive is to be mixed and spray coated together with a sterile gas and has a volume ratio of the fibrinogen solution to the thrombin solution of about 2:1 to 10:1. This adhesive is to be sprayed together with a sterile gas for the adhesion or closing of living tissue of a human being or anima l.
Patent EP-0947513-B1 (EP)
Inventor: TAKEMURA MAKOTO
IPC: C07D498/06
Filed: 1997-10-23
Granted: 2004-05-19
Abstract: The present invention relates to a compound having a tricyclic amine substituent which may have various substituents, the compound being represented by formula (I), a salt or hydrate thereof, and a hydrate of the salt and a drug containing them as an active ingredient. They exhibit excellent antimicrobial activity against Gram negative bacteria and Gram positive bacteria with a satisfactory fate and safety and are useful in the treatment of infectious diseases. <CHEM>     wherein Q preferably represents the following partial structure which may have various substituents: <CHEM> o
Patent EP-0921736-B1 (EP)
Inventor: VAZ GUY ANDREW
IPC: A43B7/32
Filed: 1997-03-25
Granted: 2002-02-06
Abstract: A boot (10) adapted to provide an improved level of protection against explosive blasts is described. In one embodiment, the boot has a sole (12), an upper (11) and a cocoon (13) portion which substantially encloses the foot. The cocoon can be comprised of an aramid weave (21), and/or, a further layer of carbon fibre (22) and/or woven ceramic fibres or ceramic/glass-ceramic woven composite fibres. The sole can incorporate layers of woven aramid and carbon fibres and a deflector plate (23) to provide enhanced protection. In an alternative embodiment, the cocoon can surround the boot and provide a quick and relatively inexpensive means of improving the blast protection to a wearer.
Patent EP-0900793-B1 (EP)
Inventor: TAKEMURA MAKOTO
IPC: C07D401/04
Filed: 1997-04-24
Granted: 2002-07-24
Abstract: A quinolone derivative represented by formula (I): <CHEM> wherein R<1> represents a cycloalkyl group; R<2> represents a hydrogen atom, an amino group, a hydroxyl group, a thiol group, a halogenomethyl group, an alkyl group, an alkenyl group, an alkynyl group, or an alkoxyl group; R<3> represents an amino group, a halogenomethyl group, a halogenomethoxyl group, an alkyl group, an alkenyl group, an alkynyl group, or an alkoxyl group; R<4> represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms; R<5> represents a cycloalkyl group having 3 to 6 carbon atoms; the above R<1> to R<5> may be substituted; X represents a halogen atom or a hydrogen atom; and Y represents a hydrogen atom, a phenyl group, an acetoxymethyl group, a pivaloyloxymethyl group, an ethoxycarbonyl group, a choline group, a dimethylaminoethyl group, a 5-indanyl group, a phthalidinyl group, a 5-alkyl-2-oxo-1,3-dioxol-4-ylmethyl group, a 3-acetoxy-2-oxobutyl group, an alkyl group having 1 to 6 carbon atoms, an alkoxymethyl group having 2 to 7 carbon atoms, or a phenylalkyl group having 1 to 6 carbon atoms in the alkyl moiety thereof, or a salt thereof. The compound exhibits high and broad antimicrobial activity against various bacteria including bacteria resistant to drugs and high safety.
Patent EP-0959843-B1 (EP)
Inventor: HINES LETHA MARGIE
IPC: A61F5/44
Filed: 1997-05-01
Granted: 2002-10-16
Abstract: Absorbent articles such as sanitary napkins, panty liners, adult incontinence devices and the like are disclosed. The absorbent articles described herein provide improved coverage of the wearer's undergarments and have improved side wrapping elements that fold or wrap the sides of a wearer's undergarments. The side wrapping elements are configured so that the majority of the surface area of the side wrapping elements is located laterally inward of the outwardmost portion of the main body portion of the absorbent article. The absorbent article can, thus, be thought of as having "internal flaps" that can fold around a wearer's undergarments.
Patent EP-0901378-B1 (EP)
Inventor: SALINI ALBERTO
IPC: A61K38/00
Filed: 1997-05-20
Granted: 2002-04-17
Abstract: A description is given of new pharmaceutical compositions containing cyclosporine, combined with a carrier comprising at least a derivative of alpha-glycerophosphoric acid, such as alpha-glycerophosphorylcholine, alpha-glycerophosphorylserine, alpha-glycerophosphorylethanolamine and alpha-glycerophosphoryl-myo-inositol, which allow cyclosporine bioavailability to significantly increase.
Patent EP-0907866-B1 (EP)
Inventor: FRANKLIN JAMES BRUCE
IPC: G02B6/00
Filed: 1997-06-17
Granted: 2008-06-11
Abstract: An optical conduit (53) for transmitting and releasing luminescent radiation (61, 62, 63) emitted from a luminescent concentrator (51), the luminescent concentrator (51) and optical conduit (52) comprising an optical system which is adapted to release to an area to be illuminated the luminescent radiation which is otherwise trapped in the optical system by total internal reflection. The optical conduit (53) includes a luminaire (57), such as a plurality of scattering regions for scattering trapped light so that the scattered light acquires the angle of incidence required to released from the conduit (53). The scattering regions may be provided by shape irregularities on the surface of the conduit (53) or inhomogeneities within the conduit (53). The conduit (53) may consist of flexible overlaid light guides (65a, 65b and 65c) and a luminaire fitting (55) optically coupled thereto.
Patent EP-0958171-B1 (EP)
Inventor: MABRY JAMES R
IPC: B65B7/16
Filed: 1997-06-02
Granted: 2004-09-08
Abstract: La présente invention concerne procédé et un appareil permettant d'emballer un produit dans une barquette (14) pourvue d'un rebord (22) extérieur. Le procédé consiste d'abord à fixer une bande continue perméable (24) sur un pourtour intérieur, puis à la séparer par découpe de la zone de fixation de façon à former un couvercle perméable. Le procédé consiste ensuite à fixer sur un pourtour extérieur du rebord une bande continue imperméable, puis à la découper de façon à constituer un couvercle imperméable arrachable par pelage. Lors de la découpe de la bande continue perméable, on protège le pourtour extérieur du rebord contre toute dégradation en relevant la bande continue perméable au-dessus du pourtour extérieur du rebord et en découpant de la bande continue par la partie surélevée. Dans le cas d'un conditionnement de viande rouge fraîche, il est possible de faire dans la barquette un vide partiel et de la remplir au moins partiellement d'un mélange gazeux appauvri en oxygène par rapport à l'air. Avant la vente au détail, il est possible de retirer le couvercle imperméable pour permettre à la viande de reprendre sa couleur rouge.
Patent EP-0910685-B1 (EP)
Inventor: SOEDERBERG STAFFAN
IPC: C23C16/36
Filed: 1997-06-27
Granted: 2002-02-13
Abstract: There is provided a coated cutting insert particularly useful for finishing operations in milling of grey cast iron. The insert has a fine-grained WC-Co cemented carbide body and a coating of multiple layers of TiCxNy deposited at conditions aiming to minimize the decarburization of the cutting edge without any negative effects on the substrate. There is also disclosed a method of applying a TiCxNy layer by CVD technique on a cemented carbide cutting insert without eta phase formation and without etching of the binder phase.
Patent EP-0909500-B1 (EP)
Inventor: BJORKMAN JAN
IPC: H04L12/413
Filed: 1997-06-24
Granted: 2002-09-25
Abstract: L'invention concerne un commutateur de télécommunication avec un lien Ethernet interne, connecté à une parite commutateur de groupe/commutateur temporel du commutateur à travers plusieurs processeurs d'internet. La partie commutateur de groupe/commutateur temporel sert à commuter des communications de données entre les lignes d'abonnés et les lignes interurbaines et entre ces lignes et les processeurs d'interface. Le lien Ethernet sert de concentrateur pour des communications de données par paquets transportées à travers les lignes d'abonnées/lignes interurbaines et maniés par commutation. Les processeurs d'interface servent à insérer sélectivement de communications de données par paquets dans le lien Ethernet et à les en extraire sélectivement. On établit une connexion par le lien Ethernet avec un point d'accès à Internet, pour permettre une communication concentrée de paquets de données avec le réseau Internet.
Patent EP-0909285-B1 (EP)
Inventor: OSTOJA STARZEWSKI KARL-HEINZ A
IPC: C08F10/02
Filed: 1997-07-02
Granted: 2000-10-04
Abstract: Cycloolefin copolymers for use for optical data memories, can be prepared by copolymerization of monomers from the group consisting of cyclic olefins, alpha-olefins having 2 or more C atoms and optionally conjugated or non-conjugated diolefins, the catalysts employed being metallocene compounds or pi complex compounds of the formulain whichCpI and CpII represent carbanions having a cyclopentadienyl-containing structure,piI and piII represent charged or electrically neutral pi systems,D represents a donor atom andA represents an acceptor atom,where D and A are linked by a reversible coordinate bond such that the donor group assumes a positive (part) charge and the acceptor group assumes a negative (part) charge,M represents a transition metal of sub-group III, IV, V or VI of the Periodic Table of elements (Mendeleev), including the lanthanides and the actinides,X denotes an anion equivalent andn denotes the number zero, one, two, three or four, depending on the charge of M.
Patent EP-0937104-B1 (EP)
Inventor: ESMON CHARLES T
IPC: C07K14/74
Filed: 1997-11-07
Granted: 2005-03-23
Abstract: The promoter of the EPCR gene has been isolated from both murine (SEQ. ID No. 1) and human (SEQ. ID No. 2) genomic libraries. The promoter includes a region (nucleotides 3130 to 3350 of SEQ. ID No. 1 which affects selective gene expression in endothelial cells), and a region (nucleotides 2270 to 2840 of SEQ. ID No. 1) which affects selective gene expression in large vessel endothelial cells, as compared to expression in all endothelial cells. The EPCR promoter contains a thrombin responsive element, CCCACCCC (SEQ. ID No. 3), (murine, nucleotides 3007 to 3014 SEQ. ID No. 1 and human, nucleotides 2722 to 2729 SEQ. ID No. 2). The EPCR also contains a serum response element (nucleotides 2990 to 3061 of SEQ. ID No. 1). The regulatory sequences present in the EPCR promoter can be used for thrombin or serum controlled recombinant gene expression specific to either all endothelial cells or primarily endothelial cells of large vessels. Therapeutic strategies include the use of the minimal promoter for expression of therapeutic agents during times of increased thrombin/platelet activation or regional trauma in all endothelial cells or the use of the large vessel specific promoter for regional specific expression in the endothelial cells of large vessels for use in delivery.
Patent EP-0948761-B1 (EP)
Title: Controle en direct dans une installation de traitement chimique
Inventor: MCDONALD MICHAEL F
IPC: G01N21/35
Filed: 1997-12-31
Granted: 2001-06-20
Abstract: La présente invention concerne une installation de traitement permettant de fabriquer du caoutchouc halobutyle fournissant un contrôle en direct et une régulation des paramètres de traitement de manière à contrôler les propriétés du produit. Le procédé incorpore un système de mesures in situ qui ne nécessite pas de prélèvement de matériau échantillon dans le processus. Ce procédé utilise un spectromètre infrarouge à transformée de Fourier (FTNIR), des câbles à fibre optique, un viscosimètre permettant de mesurer la viscosité d'une solution et un dispositif de température à résistance (RTD) de manière à mesurer la température. Un système analyseur de traitement en direct, en temp réel, utilisant un programme contraint d'analyse spectrale principale prévoit la propriété du produit polymère et fournit le système de contrôle de traitement qui analyse les données en utilisant les relations dérivées entre les propriétés physiques du polymère, les mesures spectrales et les valeurs de viscosité de fluide et de température. On utilise les différences entre les propriétés prévues et les propriétés désirées pour contrôler les paramètres de traitement. Ledit procédé peut également être utilisé dans une grande variété d'installations de traitement chimique.
Patent EP-0855524-B1 (EP)
Inventor: GOELDI MICHAEL
IPC: F16B33/00
Filed: 1998-01-17
Granted: 2003-04-23
Abstract: The fastener consists of a nut-like part and a screw. The nut (3) has a stop collar (5) and a tubular section (6) to mesh with a threaded part (7) of the screw (4). The tubular section has external ribs (11) for anti-turning effect and anti-loss effect, after the fastener has been fitted into a bore (10) in the panel (1) to be fastened. The threaded part of the screw cuts a thread in the nut when being screwed in. Nut and screw are fitted into opposite ends of bores in panel and substructure (2).
Patent EP-0875303-B1 (EP)
Inventor: ROHDE WOLFGANG PROF DR
IPC: B21B37/28
Filed: 1998-04-28
Granted: 2004-02-04
Abstract: The method concerns operation of a mill for hot and cold rolling of flat products in single or multiple arrangements of roll stands with two or more rolls. Control of the roll gap takes place with correction of the force difference between the roll drive and operator ends, and compensation of the settings correcting the bending and balancing forces. The method is characterised by the fact that the control system has an additional corrective quantity formed through measurement of the horizontal forces on all individual rolls.
Patent EP-0903962-B1 (EP)
Inventor: HUGHES JOHN THOMAS
IPC: H05B3/74
Filed: 1998-09-08
Granted: 2005-02-16
Abstract: A method of manufacturing an electric heater assembly with a plurality of electric heating units includes the steps of providing a tray-like support (1) and moulding microporous thermal and electrical insulation material into the support. The tray-like support (1) is formed with a number of dish-like recesses (2), each dish-like recess comprising a base (4) and a surrounding wall (5). The microporous thermal and electrical insulation material is moulded into each dish-like recess to form a base layer (6) against the base (4) of each dish-like recess and an upstanding wall layer (7) against the surrounding wall (5) of each dish-like recess, the base layer (6) being formed integrally with the wall layer (7). At least one electric heating element (12) is provided in each dish-like recess (2), the heating element being supported on or adjacent to the base layer (6). The electric heater assembly is adapted for use behind a plate (10) to provide a plurality of discrete heating zones on the plate. <IMAGE>
Patent EP-1013124-B1 (EP)
Inventor: GRUBECK HANS GEORG
IPC: H04B7/005
Filed: 1998-01-09
Granted: 2005-08-24
Abstract: L'invention concerne un procédé et un dispositif permettant d'affecter des stations mobiles (MS1-MS4) à un 'canal multi-utilisateur' (CH1, CH2) dans un système de radiocommunication. A l'appui d'informations sur les stations mobiles (MS1, MS2 et MS3, MS4 respectivement), les demandes de puissance (P) émanant d'une station de base (BS) avec laquelle les stations mobiles communiquent, les intervalles de temps effectifs pour la transmission d'informations (T) et/ou le spectre de puissance angulaire (a1, a2) pertinent des canaux (respectivement CH1 et CH2) de la station de base (BS) sont affectés de telle manière que l'énergie totale émise au départ de chaque station de base (BS) soit minimisée pour la transmission d'informations aux stations mobiles (MS1-MS4) qui lui sont associées. On obtient ainsi la réduction du niveau total des interférences dans le système de radiocommunication dont les stations de base (BS) font partie, ce qui entraîne une meilleure efficacité du système.
Patent EP-0956286-B1 (EP)
Inventor: SENANAYAKE CHRIS HUGH
IPC: C07D211/34
Filed: 1998-01-20
Granted: 2003-04-02
Abstract: Processes for preparing compounds having the general formula: wherein R1a is protected carboxy, carboxy, hydroxymethyl, protected hydroxymethyl, or methyl are disclosed. Processes of the invention begin with a starting material of the general formula IV wherein R1 and R2 are as defined in the specification.
Patent EP-0969759-B1 (EP)
Inventor: LIEBERS STEVEN B
IPC: A61B3/032
Filed: 1998-03-04
Granted: 2006-06-14
Abstract: A vision tester comprising a front wall and a back wall. Printed matter comprising words appears on the back wall, which is approximately 14 inches (35.6 cm.) from the front wall. The printed matter is exposed to ambient light from the top and front. The front wall has an opening through which the user of the vision tester looks. A plurality of magnifying lenses, of different diopter ratings, are selectively positionable behind the opening. Indicia appear to indicate the diopter rating of each lens. The user of the vision tester can determine the diopter rating of the appropriate lens needed for reading by determining which lens renders the printed matter clear and readable.
Patent EP-0977609-B1 (EP)
Inventor: BLAISE GILBERT
IPC: A61M16/20
Filed: 1998-03-13
Granted: 2002-08-21
Abstract: An injection system for the delivery of a gaseous substance to a patient respiratory system is described herein. The injection system includes a control unit and a valve assembly including a valve and a valve actuator allowing partial opening of the valve and controlled by the control unit. The control unit is supplied with gas flow data and controls the valve assembly so that the opening of the valve is a function to the gas flow to thereby enable the control over the concentration of the gaseous substance delivered to the patient.