baber/WOPTO huggingface dataset:
Patent GB-1319173-A (GB)
Title: 7-acylated-3-substituted cephalosporin compounds
IPC: C07D501/20
Filed: 1971-06-17
Abstract: 1319173 7 - Acylated - 3 - substituted cephalosporins FUJISAWA PHARMACEUTICAL CO Ltd 17 June 1971 28462/71 Heading C2A The invention comprises cephalosporins of the general Formula I wherein R is hydrogen, optionally substituted alkyl having 1 to 4 carbon atoms, optionally substituted aryl, thenyl or furyl radicals, R<SP>2</SP> is an acyl radical containing more than one carbon atom, R<SP>3</SP> is a hydrogen atom, an azido group or a heterocyclic-thio radical and M is a hydrogen atom or a pharmaceutically acceptable cation. A process for the preparation of compounds of Formula I comprises acylating a compound of Formula II with a disubstituted acetic acid of Formula III or with a reactive derivative thereof. A further process for the preparation of compounds of Formula I comprises reacting a compound of Formula IV with a nucleophile of formula R<SP>3 1</SP>-H wherein   R<SP>3 1</SP> is azido or a heterocyolic-thio radical or with an alkali metal salt thereof. A third process for the preparation of compounds of Formula I comprises reacting a compound of Formula VI with a silylating agent, reacting the resulting silylated compound with a halogenating agent to give a halogenated compound which is reacted with an alkanol or alkali metal alkoxide. These reactions are followed by acylation with a disubstituted acetic acid of Formula III or with a reactive derivative thereof and hydrolysis of the acylated product. A fourth process for preparing the compounds of Formula I comprises reacting a compound of Formula VIII with a carboxylic acid of formula R<SP>2</SP>-OH or with a reactive derivative thereof. Pharmaceutical preparation containing compounds of Formula I may be prepared which are suitable for oral or parenteral administration.
Patent GB-1321909-A (GB)
Title: Boat shaft
IPC: B63H23/36
Filed: 1970-09-15
Abstract: 1321909 Arrangement and disposition of propeller shafts P J SCOTT-SMITH 15 Sept 1971 [15 Sept 1970] 44051/70 Headings B7S and B7V Means for mounting a shaft 10, such as a propeller shaft, in a boat comprises a first tube member 2 adapted to be fixed to the boat and receiving the shaft with lateral clearance therebetween, and a second tube member 6 for closely holding the shaft for rotation; the first and second tube members being sealingly connectible at their end faces and adjustable with respect to each other in a direction transverse to the shaft axis. The second tube member 6 comprises a packing gland body externally threaded for receiving a lock nut 9<SP>1</SP> and a packing gland 9 for securing a self-lubricating packing 8. The member 6 is fixed to the tube by means of a clamping plate 5 engaging a flange 6<SP>11</SP> of the body 6. A water sealing gasket 7 is compressed between the flanges 2<SP>1</SP> and 6<SP>11</SP> when the plate 5 is bolted to the shaft flange 2<SP>1</SP>. The shaft 10 may be lubricated via grease nipple 11.
Patent GB-1327033-A (GB)
Title: Method for developing silver halide emulsions
IPC: G03C8/06
Filed: 1969-10-27
Abstract: 1327033 Photographic silver halide development AGFAGEVAERT 2 Oct 1970 [27 Oct 1969] 52565/69 Heading G2C A photographic non-colour-forming development method comprises developing an exposed silver halide material with an aqueous alkaline composition in the presence of a hydroxylamine developing agent and a compound of the formula:- wherein Y is -OH, -NH 2  or -N(R 3 )R 4  where R 3  is alkyl and R 4  is alkyl or substituted alkyl and each of X 1  and X 2  is hydrogen, halogen or an electron-donating group, and wherein (i) when Y is -OH or -NH 2 , R 1  is H 1  alkyl, substituted alkyl or ethylene, substituted ethylene, propylene or substituted propylene attached to the adjacent ortho position of the benzene ring, and R 2  is ethylene, substituted ethylene, propylene or substituted propylene attached to the ortho position of the benzene ring, or when Y is -NH 2 , X 1  is hydrogen and X 2  is an electron-donating group, R 2  may be alkyl or substituted alkyl, or R 1  and R 2  may form together with the N-atom to which they are attached a pyrrolidine ring; and (ii) when Y is -N(R 3 )R 4 , X 1  and X 2  are both hydrogen and R 1  is alkyl, ethylene, substituted ethylene, propylene or substituted propylene attached to the ortho position of the benzene ring and R 2  is alkyl or substituted alkyl (provided not more than one of R 2  and R 4  is substituted alkyl) or, when R 1  is attached to the ortho position of the benzene ring, R 2  may further be hydrogen. Compounds specified include 1-(4-sulphobutyl)-6-diethylamino -1:2:3:4- tetrahydroquinoline, 2-amino-4-diethylaminoaniline sulphate, 1-ethyl-6-hydroxy- 1:2:3:4 -tetrahydro-quinoline hydrochloride and 9- hydroxy-julolidine, and developing agents include hydroxylamine and N-methyl-hydroxylamine hydrochlorides and N:N-diethyl-hydroxylamine oxalate. A superadditive development effect is obtained.
Patent GB-1336130-A (GB)
Title: Gaiters for protecting torque transmission couplings
IPC: F16D3/84
Filed: 1969-11-14
Abstract: 1336130 Shaft couplings SKF (UK) Ltd 8 Dec 1970 [14 Nov 1969] 58239/70 Divided out of 1336129 Heading F2U  A sealing cover 14 for a shaft coupling consists of a resilient sleeve with transverse corrugations 44, the troughs of which carry external reinforcing rings 45 made of metal or plastics. The corrugations may be circular with separate circular rings in the troughs, Fig. 3 (not shown), but preferably they and the reinforcement are of continuous helical form. The latter may be embedded in the sleeve during manufacture. As shown the cover is applied to a universal joint 13 of the type decribed in Specification 1,336,129 associated with a sliding splined coupling 11, 12, or it may be associated with a torsionally flexible joint, Fig. 3.
Patent GB-1336952-A (GB)
Title: Platform for cloth laying machines
IPC: B65H45/103
Filed: 1971-11-02
Abstract: 1336952 Laying fabrics CUTTING ROOM APPLIANCES CORP 2 Nov 1971 50879/71 Heading D1S An operator carrying platform 30 is attached to a reciprocatable carriage 11 of a cloth laying machine. The platform 30 moves over the floor on wheels 59, 78 and is restricted to straight line motion by the insertion of its guide wheels 66 into guide means 31, comprising walls 61, 62 and 64. The wheels 17 of carriage 11 move within tracks 18 on laying table 12. A telescopic linkage 32 is pivotable on carriage 11 and is secured by a quick release bolt. The linkage may be stored by collapsing tube 87 over tube 88 and inserting them in channel 55. The operator supporting portion 70 of platform 30 may be swung into a vertical position about pintles (52, 53, Figs. 2, 2b, not shown) and latched in this position by means (79, Fig. 2a, not shown) if a travelling operator is not required. If a bumper 33 at the front at front or rear of the platform strikes an object the resulting movement of shaft 109 and its extension 110 opens switch 117 or 118 in the carriage power circuit.
Patent GB-1354677-A (GB)
Title: Process for the treatment of exhaust gases
IPC: B01D53/94
Filed: 1970-08-14
Abstract: 1354677 Purifying I C engine exhaust gas SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ NV 12 Aug 1971 [14 Aug 1970] 39409/70 Heading F1B Exhaust gases from an internal combustion engine are contacted with an NO x  conversion catalyst comprising a non-lustrous, ferromagnetic surface layer comprising an iron oxide and supported on a metallic carrier which has an average macrosurface area per unit volume of metal of at least 12 cm<SP>2</SP> /cm<SP>3</SP>, and subjecting the resulting exhaust gases in admixture with air to one or more treatments to reduce the amount of carbon monoxide and/or hydrocarbons therein. Preferably the carrier comprises iron and the surface layer is produced by the action of the exhaust gases thereon. The carrier may be in the form of turnings, cuttings, swarf, wool, wires, fibres, ribbons, foils, corrugated ribbons or plates, spirals, helices, tubes sintered metal or foamed metal.
Patent ID-29404-A (ID)
Inventor: STEK AALBERT
IPC: G11B7/007
Filed: 2000-07-05
Abstract: A device reads an information carrier that carries identification and user information. The identification information is arranged so as to be spread over the information carrier and includes data and parities. The device includes a reader for reading the information from the information carrier and error corrector correcting errors in the information. The device further includes an organizer for organizing the information in such a way that both the identification and user information can be processed by the error corrector.
Patent ID-30453-A (ID)
Inventor: SCHONHERR M
IPC: C07C253/32
Filed: 2000-03-17
Abstract: Improved process for the preparation of granular N-alkylammoniumacetonitrile salts Iwhere R1 to R5 are hydrogen or organic radicals, and Y- is a sulfate or hydrogensulfate anion,from an aqueous solution of the compound IIwhere R6 is C1- to C4-alkyl,which comprises evaporating this aqueous solution at a temperature of from 80° C. to 250° C. and a pressure of from 10 mbar to 2 bar to give a melt, then allowing the melt to solidify, where, during or following the evaporation, customary carrier materials and/or auxiliaries can be added, and the resulting solidified compound I is converted into the desired granular form.
Patent IL-104087-A (IL)
Title: Spheronization compositions containing microcrystalline cellulose and hydrocolloid process for their preparation and solid dosage form thereof
Inventor: ERKOBONI DAVID FRANK
IPC: C08J3/00
Filed: 1992-12-14
Abstract: A particulate co-processed unattrited microcrystalline cellulose:hydrocolloid composition wherein the respective components are present in a weight ratio of from about 99:1 to 70:30. The composition is useful as a spheronizing agent for producing spheroids of uniform size and sphericity and having high drug loadings. The composition is produced by drying a slurry of the microcrystalline cellulose in an aqueous solution of the hydrocolloid. The preferred hydrocolloid is methylcellulose.
[US5725886A]
Patent IL-107342-A (IL)
Title: Azacycloalkane derivatives, their preparation, pharmaceutical compositions and poultry feed stuffs containing them
IPC: A61K31/42
Filed: 1993-10-21
Abstract: Cholesterol and ergosterol biosynthesis inhibiting compounds of the formula R2R1 R3R4 N R8 (C)n(CH2)m YCN XAR10(I) R5R6 W1W2(CH2)p R7R9 (wherein: n denotes the numbers 0 or 1; m denotes the numbers 1 or 2; p denotes the numbers 0 or 1; A denotes a single bond, a straight-chain or branched C1-17-alkylene, C217-alkenylene or C2-4-alkynylene group; W1 and W2 each denotes a hydrogen atom or W1 and W2 together denote a carbon- carbon bond; X denotes a carbonyl or sulphonyl group with the proviso that where A denotes a bond and R10 denotes a hydrogen atom then X denotes a carbonyl group; Y denotes an oxygen or sulphur atom or an LNR11 group; R1, R2, R3, R4, R5 and R6 each denotes a hydrogen atom, or one, two or three of the groups R1, R2, R3, R4, R5 and R6, independently denote an alkoxycarbonyl group, or a straight-chain or branched C1-4-alkyl group optionally substituted by a hydroxy, alkoxy, alkylthio or dialkylamino group or by a phenyl group itself optionally substituted by a halogen atom or an alkyl group, and of the groups R1, R3 and R5 one, two or three may also denote a phenyl group optionally substituted by an alkyl group or a halogen atom, and the remaining groups of groups R1, R2, R3, R4, R5 and R6 each denote a hydrogen atom; R7 denotes a hydrogen or halogen atom, or an alkyl or alkoxy group; R8 and R9 independently denote a hydrogen atom or an alkyl group; R10 denotes a hydrogen atom, a C3-6-cycloalkyl group, a phenyl group optionally substituted by a halogen atom, by a straight-chain or branched C1-4-alkyl group, by a trifluoromethyl, alkoxy, cyano, nitro, alkylsulphonyl, or phenyl group, by two trifluoromethyl groups, by two to five halogen atoms, or by a halogen atom and an alkyl group optionally substituted by a fluorine atom, or R10 denotes a pyridyl group or a thienyl group optionally substituted by a halogen atom or by an alkyl group; and R11 denotes a hydrogen atom or an alkyl group; wherein, unless otherwise stated, each alkyl or alkylene moiety contains 1 to 3 carbon atoms and each halogen atom is a fluorine, chlorine or bromine atom) and the isomers, and salts thereof.
Patent IL-108189-A (IL)
Title: 4-Hydroxy-2'-nitrobutyrophenone and tetrahydro-2-(0-nitrophenyl)- 2-furanol useful as intermediates in the preparation of a cropselective herbicide
IPC: C07C201/12
Filed: 1993-12-27
Abstract: The following are claimed: A) 4-hydroxy-2'-nitrobutyrophenone (I); B) tetrahydro-2-(o-nitrophenyl)-2-furanol (II): and C) prepn. of 4-halo-2'-nitrobutyrophenone of formula (III) comprising reacting a cpd. of formula (IV) with a 2-haloethanol cpd. of formula (V) in the presence of an aq. base and a phase transfer catalyst, opt. in the presence of an organic solvent to form (I) and/or (II), and further reacting (I) and/or (II) with a hydrogen halide to form (III). X' = halo; R = 1-4C alkyl X" = Cl or Br. The hydrogen halide is used as an excess amt. and is HCl or HBr. The solvent is water and/or an aromatic hydrocarbon such as toluene. The reaction temp. is 40-130 deg.C. One molar equiv. of the 2-haloethanol cpd. is used. The phase transfer catalyst is benzyltrimethylammonium hydroxide and the aq. base is NaOH. (I) and/or (II) can be prepd. by reacting dihydro-3-(o-nitrobenzoyl)-2(3H)-furanone with an aq. acid selected from sulphuric acid, phosphoric acid and acetic acid, opt. in the presence of an organic solvent.
Patent IL-108371-A (IL)
Title: Use of sex steroid precursors to prepare medicaments for treatment of vaginal atrophy
IPC: A61K31/57
Filed: 1994-01-19
Abstract: Sex steroid precursors such as dehydroepiandrosterone and dehydroepiandrosterone sulphate, and compounds converted in vivo to either of the foregoing, are utilized for the treatment and/or prevention of vaginal atrophy, hypogonadism, diminished libido, osteoporosis, urinary incontinence, ovarian cancer, uterine cancer, skin atrophy, for contraception, and, in combination with an estrogen and/or progestin, for the treatment of menopause. The precursors may be formulated for percutaneous or transmucosal administration. Gels, solutions, lotions, creams, ointments and transdermal patches for the administration of these precursors are provided, as are certain pharmaceutical compositions and kits which can be used for the prevention and treatment of a wide variety of conditions related to decreased secretion of sex steroid precursors by the adrenals.
Patent IL-117435-A (IL)
Title: System for detecting targets
IPC: G01S17/87
Filed: 1996-03-11
Abstract: The invention relates to an arrangement for detecting approaching high-velocity targets using a rotatable optical detector (2, 3) of the line array type. With a view to the suppression of false alarms, the arrangement moreover comprises a hollow rotation axis (4) containing a mirror (14) that can be orientated such that a detector of the staring array type, a laser range-finder or a CW Doppler laser detector, all likewise contained in the hollow rotation axis, can be directed at a potential target.
[WO9630778A1]
Patent IL-120584-A (IL)
Title: 1,2-diphenylpyrrole derivatives, use thereof for the manufacture of a medicament and pharmaceutical compositions containing the same
IPC: C07D207/325
Filed: 1997-04-01
Abstract: Compounds of formula (I) and (II): <CHEM> Äin which R is hydrogen, halogen or alkyl; R<1> is alkyl, amino or substituted amino; R<2> is optionally substituted phenyl; R<3> is hydrogen, halogen or optionally substituted alkyl; R<4> is hydrogen, optionally substituted alkyl, cycloalkyl, aryl, or aralkylÜ have valuable analgesic, anti-inflammatory, anti-pyretic and anti-allergic activities and have the ability to inhibit the production of leukotrienes and to inhibit bone resorption. They are relatively free from the side effects which generally result from the administration of compounds having these kinds of activities.
Patent IL-120800-A (IL)
Title: Method for sorting items of mail in order of delivery
IPC: B07C3/00
Filed: 1997-05-07
Abstract: A method for sorting items of mail according to the sequence of delivery points in delivery runs. The sorting process take place in a number of successive sorting operations, sorting runs. Sorting takes place according to sequence number of the delivery points within the delivery runs during the last sorting run but one, and according to delivery run during the last sorting run. During said last sorting run, a suitable number of sections of a sorting apparatus have been reserved for each delivery run, and each delivery run is subdivided into as many segments, e.g. four. The items of mail for the first segment of a delivery run, in the example for the first quarter of the sequence numbers, are deposited in the first of the sections reserved for said delivery run, those for the second segment in the second section, and so forth. Upon completion, the items of mail for a delivery run are collected by placing the delivery segments in succession. <IMAGE>
Patent IL-123615-A (IL)
Title: Method for marking objects and objects being marked with such method
IPC: A23G4/04
Filed: 1996-08-20
Abstract: PCT No. PCT/SE96/01027 Sec. 371 Date May 11, 1998 Sec. 102(e) Date May 11, 1998 PCT Filed Aug. 20, 1996 PCT Pub. No. WO97/10162 PCT Pub. Date Mar. 20, 1997Method for marking an object where the object is placed in a package whereby a pattern in said package is caused to make a marking in said object. Objects being marked with the above method. The invention is especially useful for marking solid or semi-solid formulations of drugs, candy and food-stuff. Specifically the invention is useful to mark nicotine-containing chewing gums. Other solid or semi-solid objects can equally well be marked using the present invention.
Patent IL-123899-A (IL)
Title: Process for the purification of dimethyl sulphoxide (dmso)
IPC: C07C315/06
Filed: 1996-11-15
Abstract: PCT No. PCT/FR96/01806 Sec. 371 Date May 12, 1998 Sec. 102(e) Date May 12, 1998 PCT Filed Nov. 15, 1996 PCT Pub. No. WO97/19057 PCT Pub. Date May 29, 1997This process consists in placing liquid DMSO with a low water content in contact with an ion exchange resin in -SO3H form, and then in separating the liquid from the resin. The DMSO thus obtained has a content of iron cation tracer element of less than or equal to 1 ppb and a content of Na cation tracer element of less than or equal to 2 ppb.
Patent IL-136706-A (IL)
Title: Modular imaging apparatus
IPC: H01L27/14
Filed: 1998-11-19
Abstract: Apparatus for imaging radiation, said apparatus comprising: a plurality of tiles (90.1) (90.2), each tile comprising an imaging device (16) having an array of radiation detector cells (42, 44); a plurality of modules (100), each module supporting at least two tiles; and a module support structure (320), said support structure supporting said plurality of modules, wherein said plurality of modules are removably mounted on said support structure. 1928 ז' באב התשס" ד - July 25, 2004
Patent IL-138857-A (IL)
Title: Cd19xcd3 specific polypeptides and uses thereof
IPC: C07K19/00
Filed: 2000-10-04
Abstract: Described are novel single-chain multifunctional polypeptides comprising at least two binding sites specific for the CD19 and CD3 antigen, respectively. Further provided are polypeptides, wherein the above-described polypeptide comprises at least one further domain, preferably of pre-determined function. Furthermore, polynucleotides encoding said polypeptides as well as to vectors comprising said polynucleotides and host cells transformed therewith and their use in the production of said polypeptides are described. In addition, compositions, preferably pharmaceutical and diagnostic compositions are provided comprising any of the afore-described polypeptides, polynucleotides or vectors. Described is also the use of the afore-mentioned polypeptides, polynucleotides and vectors for the preparation of pharmaceutical compositions for immunotherapy, preferably against B-cell malignancies such as non-Hodgkin lymphoma.Described are novel single-chain multifunctional polypeptides comprising at least two binding sites specific for the CD19 and CD3 antigen, respectively. Further provided are polypeptides, wherein the above-described polypeptide comprises at least one further domain, preferably of pre-determined function. Furthermore, polynucleotides encoding said polypeptides as well as to vectors comprising said polynucleotides and host cells transformed therewith and their use in the production of said polypeptides are described. In addition, compositions, preferably pharmaceutical and diagnostic compositions are provided comprising any of the afore-described polypeptides, polynucleotides or vectors. Described is also the use of the afore-mentioned polypeptides, polynucleotides and vectors for the preparation of pharmaceutical compositions for immunotherapy, preferably against B-cell malignancies such as non-Hodgkin lymphoma.
Patent IL-147792-A (IL)
Title: Estimating interference in a communication system
IPC: H04B17/00
Filed: 2002-01-23
Abstract: A method and apparatus for improving the transmission of an information signal having message information. A received information signal is formed from an information signal transmitted through an information channel. The received information signal has signal noise. The message information is removed from the received information signal to provide a symbol sequence that is then applied to a first filter to provide a first filtered signal. The power of the first filtered signal is determined and applied to a second filter to provide a second filtered signal representative of the signal noise of the received information signal.
Patent IL-149332-A (IL)
Title: Method for producing peroxydicarbonates and their use in the radical polymerization of monomers
IPC: C08K5/14
Filed: 2002-04-24
Abstract: A process for producing peroxydicarbonates comprising first reacting at least one inorganic peroxide with at least one alkali metal hydroxide to form at least one alkali metal peroxide. The at least one alkali metal peroxide is added to a mixture of at least one haloformate, at least one dispersant and water. The mixture is homogenized during the entire reaction to form a peroxydicarbonate. The peroxydicarbonate is dispersed as small droplets of from 1 to 10 microns in size in the aqueous mixture. The entire mixture is added to a polymerization reactor containing an ethylenically unsaturated monomer. The peroxydicarbonate functions as the free radical initiator to polymerize the monomer. The peroxydicarbonate is substantially free of organic solvents and plasticizers. The resulting polymers are of high quality.
Patent IL-163462-A (IL)
Title: Cerium oxide powder
IPC: C01F17/235
Filed: 2004-08-11
Abstract: Polycrystalline cerium oxide powder (I) in the form of aggregates of primary particles has a specific surface area of 70-150 m 2>/g, average primary particle diameter of 5-20 nm and average projected aggregate diameter (equivalent circle diameter, ECD) of 20-100 nm. Independent claims are included for: (1) the preparation of (I); (2) dispersions containing (I); and (3) the production of the dispersions.
Patent IL-177967-A (IL)
Title: Compositions of restricted cells capable of rapid growth which produce proliferation suppressive materials and uses thereof
IPC: A61K35/13
Filed: 2006-09-07
Abstract: Compositions of matter are described which contain restricted cancer cells. When so restricted, the cells produce an unexpectedly high amount of material which suppresses cancer cell proliferation. The phenomenon crosses cancer type and species lines. Processes for making these compositions, and their use, are also described.