baber/WOPTO huggingface dataset:
Patent CA-3128738-A1 (CA)
Title: A cho-dg44 derivative cell line expressing an antibody against insulin-like growth factor receptor 1
Inventor: HANSEN SILKE
IPC: C12P21/08
Filed: 2007-04-10
Abstract: The invention provides a method for selecting a CHO cell line for the recombination production of a monoclonal antibody of human lgG1 or lgG3 type being glycosylated with a sugar chain at ASN297, said antibody being characterized in that the amount of fucose within said sugar chain is at least 99% and in addition the amount of NGNA is 1% or less and/or the amount of N-terminal alpha 1,3 galactose is 1% or less, said method comprising cultivating a CHO cell transfected with an lgG1 or lgG3 antibody, under DHFR selection pressure, picking single clones, expanding the clones and selecting a clone producing an antibody with the glycosylation pattern according to the invention.
Patent CA-3129629-A1 (CA)
Inventor: VILLAX PETER
IPC: H04L29/06
Filed: 2020-02-11
Abstract: Un procédé et un dispositif sont présentés pour enregistrer de manière sécurisée un utilisateur d'ordinateur dans un système informatique au moyen d'un identifiant anonyme, ce qui permet d'éliminer l'utilisation d'un nom d'utilisateur et d'un mot de passe et de nécessiter d'un seul clic ou contact tactile par l'utilisateur pour se connecter à l'ordinateur. L'identifiant anonyme identifie de manière unique l'utilisateur et peut être utilisé comme clé cryptographique.
Patent CA-3130316-A1 (CA)
Title: Superconductor ground plane patterning geometries that attract magnetic flux
Inventor: HERR ANNA Y
IPC: H01L27/18
Filed: 2020-02-05
Abstract: Superconducting integrated circuit (100) layouts are proofed against the detrimental effects of stray flux by designing and fabricating them to have one or more ground planes (104) patterned in thex y plane with a regular grid (106) of low-aspect-ratio flux-trapping voids (202). The ground plane(s) can be globally patterned with such voids and thousands or more superconducting circuit devices and wires can thereafter be laid out so as not to intersect or come so close to the voids that the trapped flux would induce supercurrents in them, thus preventing undesirable coupling of flux into circuit elements. Sandwiching a wire layer between patterned ground planes permits wires to be laid out even closer to the voids. Voids of successively smaller maximum dimension can be concentrically stacked in pyramidal fashion in multiple ground plane layers having different superconductor transition temperatures, increasing the x-y area available for device placement and wire-up.
Patent CA-3130982-A1 (CA)
Title: System and method for human-computer interaction with eye-tracking device to determine local coordinates of the pupil relative to the pointing surface
Inventor: WANG YUBO
IPC: A61B3/113
Filed: 2021-09-16
Abstract: A system and method for hands-free human-computer interaction using a head-mounted eye-tracking device (fig.1). The device uses fiducials placed on the corners of a user interface (fig.2) or displayed on a screen itself to determine the distance and location of the Ul (User Interface, commonly a screen). Using the location and distance of the Ul and gaze direction of the eyes, the system can determine where on the Ul the eyes are gazing and move a pointing device (cursor) accordingly. It significantly reduces the component costs associated with traditional gaze interaction methods.
Patent CA-3134330-A1 (CA)
Title: Image registration method and system thereof
Inventor: LU CHIH
IPC: G06F17/00
Filed: 2020-04-30
Abstract: Provided herein are image registration methods comprising providing a wide view image of a target area by a first imager; providing a narrow view image of the target area by a second imager; aligning the narrow view image on the wide view image of the target area; capturing an optical image by an optical imager, wherein the optical imager is configured to locate the optical image in the narrow view image; and displaying the position of the optical image on the narrow view image and the wide view image of the target area; and the systems thereof.
Patent CA-3134511-A1 (CA)
Title: Compositions et methodes de reprogrammation de tcr faisant appel a des proteines de fusion
Inventor: QUINTAS-CARDAMA ALFONSO
IPC: A61P35/00
Filed: 2020-03-20
Abstract: L'invention concerne des méthodes de dosage et d'administration pour le traitement d'un cancer exprimant la mésothéline chez l'homme, consistant à administrer, par exemple, une pluralité de lymphocytes T exprimant une protéine de fusion de récepteur de lymphocyte T anti-mésothéline.
Patent CA-3134627-A1 (CA)
Inventor: PALANKER DANIEL V
IPC: A61N1/05
Filed: 2020-03-25
Abstract: We provide a 3-dimensional configuration of an electrode array for neural cell stimulation designed to leverage migration of retinal cells into voids in the subretinal space. Walls surrounding each pixel align the electric field vertically, matching the orientation of bipolar cells in the retina, and thereby reduce the stimulation threshold. These walls also decouple the field penetration depth from the pixel width, enabling a decrease of the pixel size down to cellular dimensions. Inner retinal cells migrate into the electrode cavities, which enables very efficient stimulation. Due to 1-dimensional alignment of electric field along the cavities, stimulation threshold current density does not increase significantly with the reduced pixel size, unlike the quadratic increase seen with planar arrays.
Patent CA-3134668-A1 (CA)
Inventor: AKLOG LISHAN
IPC: G05D7/03
Filed: 2020-04-10
Abstract: The systems and methods of the present disclosure provides an independent passive variable resistor that can be interposed between a fluid reservoir at an inlet pressure and receptacle at an outlet pressure. The resistor can adjust resistance to the pressure difference from the input to the output so that the flow rate through it is a constant rate. The resistor can include a moveable element and a biasing mechanism located in a chamber to create a flow channel. Each side of the moveable element is exposed to the inlet and outlet pressures and moves within the flow channel to modify the resistance of the flow through the chamber in response to the pressures. The balance of these forces determines the position moveable element, which interacts with the fluid channel to determine the flow resistance through variable resistor. The biasing mechanism can provide the necessary pressure to establish equilibrium flow rate.
Patent CA-3136231-A1 (CA)
Title: Couche barriere pour substrat cellulosique
Inventor: DAG TAHSIN
IPC: D21H19/52
Filed: 2020-04-20
Abstract: La présente invention concerne un procédé de fabrication de substrats revêtus, dans lequel un premier revêtement fluide, biodégradable et augmentant l'étanchéité aux gaz est appliqué sur un substrat contenant de la cellulose. Pour obtenir un emballage exclusivement composé d'ingrédients naturels et doté d'une bonne imperméabilité, une seconde couche imperméable composée de cires et/ou de lipides d'origine animale et/ou végétale est appliquée sur la première couche.
Patent CA-3136401-A1 (CA)
Title: Procede de production d'une structure de type tissu biologique
Inventor: HIYOSHI Hideyuki
IPC: C12N5/0775
Filed: 2020-04-09
Abstract: La présente invention vise à fournir un nouveau procédé permettant de produire une structure de type tissu biologique comprenant des cellules différenciées dérivées de cellules souches pluripotentes. La présente invention concerne un procédé de formation d'une structure de type tissu biologique avec des vaisseaux sanguins dérivés de l'hôte ou des tissus conjonctifs par implantation, dans des tissus biologiques, d'une composition comprenant l'état dans lequel des cellules dérivées de cellules souches pluripotentes sont disposées après avoir été dispersées dans un matériau biocompatible pour induire la différenciation de cellules.
Patent CA-3139483-A1 (CA)
Title: Gyroscup - a gyroscope based beverage stabilizer
Inventor: DUCHESNEAU MARTIN
IPC: F16M13/04
Filed: 2021-11-19
Abstract: A hand-held device used to stabilize an open top beverage vessel using the principle of gyro-stabilization caused by 3 discs attached to each other using pivots on 2 perpendicular and horizontal axis. Attached to the outer-most disc is a handle designed to be manipulated by a human hand. The drinking vessel rests inside the inner-most disc, linked to the center disc by 2 diametrically opposed nipples (or pins) resting in grooves on the center disc. This center disc is in turn linked to the outer-most disc by the same principle but perpendicular (90deg offset) to the first. The pivotal action compensates for forces applied to the vessel in order to reduce spills.
Patent CA-3141586-A1 (CA)
Title: Use of nanoparticles to tune index of refraction of layers of a polymeric matrix to optimize microoptic (mo) focus
Inventor: MCALLISTER MICHAEL
IPC: B41M3/14
Filed: 2020-05-20
Abstract: A security device (100, 600, 700, 1000, 1050) includes arrangements of image icons (110a, 110b, 615, 715, 1020), arrangements of refractive image icon focusing elements(120, 605, 705, 1010) and a sealing layer (125, 600, 1005), wherein the arrangements of refractive image icon focusing elements is disposed above the arrangements of image icons such that a portion of the arrangements of refractive image icon focusing elements projects a synthetic image, such that the arrangements of refractive image icon focusing elements contact the sealing layer along a non-planar boundary. Further, at least one of the arrangements of refractive image icon focusing elements and the sealing layer comprises an organic resin mixture having a first refractive index, and at least one of the arrangements of refractive image icon focusing elements and the sealing layer comprises a low-refractive index material, the low-refractive index material having a second refractive index.
Patent CA-3142105-A1 (CA)
Title: Method of manufacturing flake graphene
Inventor: DUZYNSKA ANNA
IPC: C01B32/19
Filed: 2020-04-15
Abstract: The invention is related to a method of manufacturing flake graphene in a liquid phase exfoliation process of graphite in oil.
Patent CA-3144549-A1 (CA)
Title: Cell for resisting transplant reaction and method
Inventor: LI ZONGHAI
IPC: C07K14/74
Filed: 2020-06-29
Abstract: The present invention relates to a cell for resisting transplant immune rejection. The cell expresses a first protein capable of identifying one or more immune effector cells of a host; preferably, the cell has an inhibition or killing function for the immune effector cells of the host. The present invention also relates to a method for preventing or regulating transplant immune rejection and a method for preventing or regulating attack of NK cells on exogenous cells.
Patent CA-3147778-A1 (CA)
Title: Novel bacterial strains
Inventor: KAUR JATINDER
IPC: A01N63/20
Filed: 2020-07-17
Abstract: The present invention relates to a substantially purified or isolated endophyte strain from a plant, wherein said endophyte is a strain of Curtobacterium flaccumfaciens and/or Arthrobacter sp., and wherein said endophyte provides improved environmental stress tolerance to plants into which it is inoculated. The present invention also relates to plants infected with the endophytes and related methods.
Patent CA-3152889-A1 (CA)
Title: Automated method for gas lift operations
Inventor: TALTON BROOKS MIMS
IPC: E21B47/06
Filed: 2020-08-19
Abstract: Disclosed is a compressor system suitable for carrying out artificial gas lift operations at an oil or gas well. Also disclosed is a method for controlling the compressor system. The methods disclosed provide the well operator with the ability to identify and maintain gas injection rates which result in the minimum production pressure. The minimum production pressure will be determined either by a bottom hole sensor or a casing pressure sensor located at the surface or any convenient location capable of monitoring pressure at the wellhead.
Patent CA-3154492-A1 (CA)
Title: System and method for deploying a collaborative robot in a glovebox
Inventor: O'BRIEN JAMES
IPC: B25J21/02
Filed: 2020-09-18
Abstract: A system (1) and method for deploying a collaborative robot (5) in a glovebox (10) are provided. The system comprises an adjustable trolley (2) including: a frame (3); a mounting plate (4) slideably mounted to the frame (3); one or more pulleys (15) configured to move the mounting plate (4) along a longitudinal axis of the adjustable trolley (2); and a plurality of wheels (9) configured to move the adjustable trolley (2) forward, backward, and rotate about the longitudinal axis of the adjustable trolley (2); a collaborative robot (5) having a proximate end and a distal end, the proximate end mounted to the mounting plate (4), and the distal end comprising an end effector (13); and a glove (7) configured to receive the collaborative robot (5), and to sealably couple with a port (11) of the glovebox (10).
Patent CA-3155942-A1 (CA)
Inventor: TOSATO FILIPPO
IPC: H04B7/0456
Filed: 2020-10-29
Abstract: Un UE détermine un PMI en effectuant au moins les étapes suivantes consistant à déterminer un ensemble intermédiaire de vecteurs à partir d'un livre de codes FD ; à former un sous-ensemble de l'ensemble intermédiaire de vecteurs ; à mapper le sous-ensemble de vecteurs sur un indicateur combinatoire ; et à former le PMI au moins à partir de l'indicateur combinatoire. L'UE envoie le PMI à un réseau sans fil. Une station de base reçoit le PMI en provenance de l'UE. Le PMI comprend un indicateur combinatoire qui est mappé sur un sous-ensemble de vecteurs provenant du livre de codes FD. La station de base détermine, au moyen du ou des PMI reçus, des informations provenant du ou des livres de codes FD à appliquer à des données pour une transmission à l'UE.
Patent CA-3156499-A1 (CA)
Title: Chinone-, hydrochinome- and naphthochinone-analogues of vatiquione for treatment of mitochondrial disorder diseases
Inventor: KEEFE DENNIS
IPC: C07D201/00
Filed: 2020-10-02
Abstract: The disclosure provides therapeutic compositions (i.e., therapeutic agents) and methods of preventing or treating Friedreich's ataxia in a mammalian subject, reducing risk factors, signs and/or symptoms associated with Friedreich's ataxia (e.g. Complex I deficiency), and/or reducing the likelihood or severity of Friedreich's ataxia. The disclosure further provides novel intermediates for the production of said therapeutic compositions and related reduced versions of said therapeutic compositions, which reduce forms may also be used as therapeutic agents (or prodrugs of the therapeutic agent(s)).
Patent CA-3157214-A1 (CA)
Inventor: DANA REZA
IPC: A61P27/02
Filed: 2020-10-08
Abstract: The present disclosure presents sealant compositions which can be used in the treatment of an ocular surface injury and methods of treating an ocular surface injury in a subject in need thereof. The sealant compositions can include methacrylated hyaluronic acid (MeHA); GelMA; optionally, poly(ethylene glycol) diacrylate (PEGDA); and a visible light-activated photoinitiator. The methods include applying a sealant composition to an applicator; placing the applicator containing the sealant composition onto a surface of the eye of a subject, wherein the surface of the eye has or is suspected of having the ocular surface injury; and photo-crosslinking the sealant composition by exposing the applicator and the sealant composition to a visible light, for example, a visible light having a wavelength of about 400 nanometers (nm) to 800 nm.
Patent CA-3158349-A1 (CA)
Title: Systeme et dispositifs de rein artificiel
Inventor: ESSALIK ABDELTIF
IPC: A61M1/16
Filed: 2020-09-29
Abstract: L'invention concerne un procédé et des dispositifs de détection d'une insuffisance rénale et de dialyse d'un sujet, l'épiderme étant soumis à une électroporation de manière irréversible sans générer de chaleur et une pression négative étant appliquée, formant des micro-conduits dans l'épiderme à partir desquels le fluide interstitiel peut être extrait, analysé et filtré pour produire par exemple un dialysat et renvoyé au sujet.
Patent CA-3158640-A1 (CA)
Title: Artefact reduction in magnetic resonance imaging
Inventor: LAZARUS CAROLE
IPC: G01R33/44
Filed: 2020-10-23
Abstract: A method of operating a low-field magnetic resonance imaging (MRI) system, the method comprising: obtaining an initial set of k-space phase-encoding coordinates; generating a sampling path through at least some of the k-space phase-encoding coordinates in the initial set to mitigate impact of eddy currents on operation of the low-field MRI system; and operating the low-field MRI system using a pulse sequence in accordance with the sampling path to obtain spatial frequency data for generating one or more magnetic resonance (MR) images of a subject.
Patent CA-3160046-A1 (CA)
Title: Agent de liberation pour une elimination amelioree de materiau valorisable de la surface d'un support de collecte modifie
Inventor: JAUNKY GUILLAUME
IPC: B03D1/12
Filed: 2020-12-11
Abstract: Appareil permettant d'éliminer des particules minérales de supports de collecte modifiés chargés comprenant un ou plusieurs solvants présentant une tension superficielle suffisamment basse. Les supports de collecte modifiés sont composés d'un matériau synthétique et présentent une surface revêtue d'un matériau hydrophobe pour assurer une liaison chimique entre les particules minérales et la surface. Les solvants conjointement avec un mécanisme de libération sont disposés pour interrompre la liaison chimique. De préférence, un tensioactif ou un tensioactif non ionique est également ajouté aux solvants.
Patent CA-3161092-A1 (CA)
Inventor: LI LIN
IPC: E04F13/18
Filed: 2021-01-11
Abstract: The invention relates to a decorative surface covering element, in particular a floor panel, ceiling panel or wall panel. The invention also relates to a panel covering, such as a floor covering, ceiling covering or wall covering, comprising a plurality of panels according to the invention. The invention further relates to a method of producing a decorative surface covering element according to the invention.
Patent CA-3162149-A1 (CA)
Inventor: ALLINGTON CHRISTOPHER JAMES
IPC: F16D59/00
Filed: 2015-12-04
Abstract: An eddy current brake configuration comprises a cylinder and a tube. The tube is configured to move rotationally relative to the cylinder and axially as a stroke into the cylinder. The tube and cylinder comprise at least one magnet and at least one conductor that interact when the tube enters the cylinder at different rates of relative rotational movement to impose an eddy current braking force against relative movement between the tube and cylinder. The eddy current brake configuration is further configured to have a bi-stable attractive force arrangement wherein tube stroke movement comprises a first magnetic attraction force and a second magnetic attraction force. The first magnetic attraction force between the tube and an external element acts to delay relative motion of the tube relative to the cylinder. When the first magnetic attraction force is overcome, the tube is free to travel axially into the cylinder. The second magnetic attraction force between the tube and a cylinder end acts to latch the tube in the cylinder.
Patent CA-3164334-A1 (CA)
Inventor: Fjeldheim Ivar
IPC: B65G1/04
Filed: 2021-01-26
Abstract: La présente invention concerne un système et un procédé pour effectuer des mesures dans des conteneurs de stockage (502) pour stocker des articles, les conteneurs de stockage (502) sont stockés dans un système de stockage automatisé comprenant une structure d'ossature (100) formant une structure de grille de stockage tridimensionnelle (104) pour stocker les conteneurs de stockage (502), la structure de grille (104) formant des colonnes de stockage verticales (105) ayant chacune une même zone horizontale définie par la taille d'une ouverture d'accès (112) des colonnes de stockage verticales (105) et un système de rail (108) étant disposé sur la structure d'ossature (100) définissant la circonférence de chaque ouverture d'accès (112) au-dessus de chaque colonne de stockage (105), le système de rail (108) fournissant des itinéraires disponibles pour des véhicules de manutention de conteneurs (201) manipulant et transférant des conteneurs de stockage (502) vers et à partir des colonnes de stockage (105), chaque véhicule (201) comprenant un dispositif de commande de véhicule (230) communiquant avec un système informatique central commandant le fonctionnement du système de stockage, et ledit système comprenant en outre une station de test (504), accessible à un véhicule de manipulation de conteneurs par l'intermédiaire du système de rails (108), avec un équipement de mesure pour mesurer des conditions atmosphériques et pour effectuer des mesures dans ledit conteneur de stockage (502) et où la station de test (504) est conçue pour communiquer des données de mesure à un système informatique.
Patent CA-3166949-A1 (CA)
Title: Human monoclonal antibodies to severe acute respiratory syndrome coronavirus 2 (sars-cov-2)
Inventor: CROWE JAMES E
IPC: C07K16/10
Filed: 2021-02-11
Abstract: The present disclosure is directed to antibodies binding to and neutralizing the coronavirus designated SARS-CoV-2 and methods for use thereof.
Patent CA-3170988-A1 (CA)
Inventor: VELEVA ANKA
IPC: C12N15/10
Filed: 2020-12-23
Abstract: L'invention concerne un procédé de création d'une formulation de particules colloïdales composites ayant une fonctionnalité avancée qui possède des propriétés hautement efficaces et efficientes. La formulation de particules colloïdales composites comprend un noyau particulaire biodégradable modifié dispersé dans une solution de polyélectrolyte bioadhésif. L'invention concerne également des procédés d'utilisation de celles-ci, comprenant, entre autres, l'application de ladite formulation sur des plantes pour le traitement de maladies.
Patent CA-3173053-A1 (CA)
Title: Loci d'hebergement surs
Inventor: JUDE JULIAN
IPC: C12N15/10
Filed: 2021-01-29
Abstract: Une cellule hôte mammifère isolée comprenant un gène hétérologue d'intérêt (GOI) est intégrée de manière chromosomique au niveau d'un site cible à l'intérieur d'une région intergénique entre une paire de gènes essentiels adjacents.
Patent CA-3176557-A1 (CA)
Title: Insulation including phase change materials
Inventor: LOHSE ALEXANDER
IPC: E04B1/74
Filed: 2021-03-22
Abstract: An insulation product demonstrating enhanced insulative properties is described herein. Generally, the insulation product comprises a fibrous insulation component and a phase change material. In certain embodiments, the phase change material may take the form of a layer disposed on a surface of the fibrous insulation component or interposed within the fibrous insulation component.
Patent CA-3176571-A1 (CA)
Inventor: PANDYA HITESH CHAMPAKLAL
IPC: A61K39/395
Filed: 2021-04-01
Abstract: La présente divulgation concerne l'utilisation d'un antagoniste de liaison à l'axe IL33 pour le traitement et la prévention du syndrome de détresse respiratoire aiguë (ARDS) et/ou de ses symptômes.
Patent CA-3176837-A1 (CA)
Inventor: GUO RENFENG
IPC: C07K16/18
Filed: 2021-05-06
Abstract: La présente invention concerne des anticorps qui se lient spécifiquement à un épitope conformationnel de C5a humain. L'invention concerne en particulier des anticorps anti-C5a humanisés. Les anticorps décrits ici sont utiles en tant que principes actifs dans des compositions pharmaceutiques. Les anticorps et les compositions pharmaceutiques sont particulièrement utiles pour le traitement et la prévention de maladies ou de troubles impliquant une activité C5a pathologique.