baber/WOPTO huggingface dataset:
Patent NZ-522282-A (NZ)
Title: A gene differentially expressed in breast and bladder cancer and encoded polypeptides
Inventor: ZAUDERER MAURICE
IPC: A61K35/76
Filed: 2001-04-04
Abstract: Described is a human gene that is differentially expressed in human carcinoma. More specifically described is a polynucleotide encoding a human polypeptide named C35 that is over expressed in human breast and bladder carcinoma. Also described is C35 polypeptides, as well as vectors, host cells, antibodies directed to C35 polypeptides, and the recombinant methods for producing the same. Further described are diagnostic methods for detecting carcinomas, including human breast carcinomas, and the formulation and use of the C35 gene and polypeptides in immunogenic compositions or vaccines, to induce antibody or cell-mediated immunity against target cells, such as tumour cells, that express the C35 gene. Also described are screening methods for identifying agonists and antagonists of C35 activity.
Patent NZ-527640-A (NZ)
Title: HIV inhibiting N-aminoimidazole derivatives
Inventor: DE CLERCQ ERIK
IPC: A61P35/00
Filed: 2001-02-23
Abstract: Described is an N-aminoimidazole or N-aminoimidazolethione derivative, a pharmaceutically acceptable salt, a tautomer, an isomer, an ester or a glycosylation product thereof. The derivative is represented by the general formula I wherein: m is zero or 1; n is zero or 1;Rl is selected from hydrogen, methyl, ethyl, propyl or isopropyl ; R2 is selected from hydrogen and-SH; Q is selected from 1-naphtyl, 2-naphtyl, biphenyl, 2-pyridyl, 3-pyridyl, 4-pyridyl, 2 pyrimidyl, 4-pyrimidyl, 5-pyrimidyl, thienyl, carboxyl, aminocarbonyl, alkylamino carbonyl, dialkylaminocarbonyl, phenylaminocarbonyl, alkyloxycarbonyl or phenyl ; wherein alkyl is a methyl, ethyl, propyl or isopropyl and phenyl is a substituted or unsubstituted phenyl ring represented by the general formula II wherein o is 1 or 2, and R3 is selected from H, F, Cl, Br, I, hydroxy, alkyloxy, amino, alkylamino, dialkylamino, cyano, nitro, carboxyl, aminocarbonyl, alkylaminocarbonyl, alkyloxycarbonyl, methyl, ethyl, propyl, isopropyl or Cl1-3 haloalkyl; L is selected from 1-naphtyl, 2-naphtyl, biphenyl, 2-pyridyl, 3-pyridyl, 4-pyridyl, 2 pyrimidyl, 4-pyrimidyl, 5-pyrimidyl, thienyl, or a substituted or unsubstituted phenyl ring represented by the general formula III wherein p is 1 or 2, and R4 is selected from H, F,Cl, Br,I, hydroxy, alkyloxy, amino, alkylamino, dialkylamino, cyano, nitro, carboxyl, aminocarbonyl, alkylaminocarbonyl, alkyloxycarbonyl, methyl, ethyl, propyl, isopropyl or Cl1-3 haloalkyl. A proviso is explained that compound I is not selected from 1- (3-Chlorophenylamino)-2, 3-dihydro-4-methyl-5-phenyl-1H-imidazole-2-thione ;1-(2-Chlorophenylamino)-2, 3-dihydro-4-methyl-5-phenyl-1H-imidazole-2-thione; 1- (4-Chlorophenylamino)-2, 3-dihydro-4-methyl-5-phenyl-1H-imidazole-2-thione ; 1- (phenylamino)-2, 3-Dihydro-4-methyl-5-phenyl- 1H-imidazole-2-thione ; 1- (4-nitrophenylamino)-2, 3-dihydro-4-methyl-5-phenyl-1H-imidazole-2-thione ; 1- (4-methylphenylamino)-2, 3-dihydro-4-methyl-5-phenyl-1H-imidazole-2-thione ; 1- (4-methyloxyphenylamino)-2, 3-dihydro-4-methyl-5-phenyl-lH-imidazole-2-thione ;1-(benzylamino)-2, 3-dihydro-4-methyl-5-phenyl-lH-imidazole-2-thione ; 4-Methyl-5-phenyl-1-phenylamino-1H-imidazole ; 4-Methyl-5-phenyl-1- (4-nitrophenyl) amino-1H-imidazole ; 4-Methyl-5-phenyl-1- (4-chlorophenyl) amino-1H-imidazole ; 4-Methyl-5-phenyl-1- (4-methylphenyl) amino-1H-imidazole ; or 4-Methyl-5-phenyl-1- (4-methyloxyphenyl) amino-1H-imidazole. Also described are processes for preparing a derivative of the general formula I, and a pharmaceutical composition comprising the compound with antiviral activity against HIV (Human Immunodeficiency Virus) and other viruses.
Patent NZ-529183-A (NZ)
Title: Method of forming a slip-resistant photo-luminescent stair threads
Inventor: WATSON JULIAN MARK
IPC: B05D5/06
Filed: 2003-10-28
Abstract: A method of manufacturing a slip-resistant photo-luminescent device includes dispensing first and second powdered components into respective recesses provided in a substrate such as a metal strip. The first powdered component includes a resin and a friction-enhancing material, the second powdered component includes a resin and a photo-luminescent pigment. The powdered components are then heated to fuse the resins and bond them to surfaces of the respective recesses. A channel is formed between the first and second recesses for receiving traces of the first and second components that may spill from the adjacent recesses.
Patent NZ-532988-A (NZ)
Title: Erythropoietin dosing regimen for treating anemia
Inventor: FARRELL FRANCIS
IPC: A61K38/18
Filed: 2002-11-26
Abstract: Disclosed is the use of erythropoietin in the preparation of a medicament for erythropoietin treatment in a patient in need thereof, wherein the medicament is formulated for administration according to a dosage regimen by: a) dosing a patient by subcutaneous injection once every week with a therapeutically effective amount of erythropoietin until a hemoglobin increase of about 2g/dL is achieved; and b) dosing said patient by subcutaneous injection once every two weeks with an amount of erythropoietin that is greater than the amount dosed in step (a).
Patent NZ-534250-A (NZ)
Title: A device for dispensing two sided adhesive tape pieces and a refill roll for the device
Inventor: LUDVIGSEN FRITS
IPC: B65H37/00
Filed: 2003-01-13
Abstract: The device has a roll (1) of a carrier strip (2) holding pieces (3) of two sided adhesive tape and wound on a hub (5) with an outer radius and provided with a circular cogging (6), a support (7) for the roll (1) comprising a stub shaft (9) with a direction of axis around which the roll rotates when dispensing tape pieces (3), a brake pawl (23) for engagement with the circular cogging (6), a pressure base (15) being in connection with the brake pawl (23) such that the engagement of the brake pawl (23) with the cogging (6) is released by pressure on the pressure base (15), a peripheral wall (10,11) extending along a part of the periphery of the roll (1), and a path for the carrier strip (2) extending past the pressure base (15) and along a part of the outside of the peripheral wall (10,11), the pressure base (15) comprising an outer sliding surface (16,17) defining a part of the path for the carrier strip (2) with the two sided adhesive tape where the path at the pressure base (15) comprises a portion with a relative sharp curve (18) with a radius of curvature being essentially smaller than the outer radius of the hub. The two sided adhesive tape (3) is of a relatively rigid material, the two sided adhesive tape (3) being separated from the carrier strip (2) when the latter passes said relatively sharp curve (18) during advance.
Patent NZ-534477-A (NZ)
Title: Dampened compression spring rod
Inventor: ADOLINE JACK W
IPC: F16F9/32
Filed: 2003-01-10
Abstract: A compression spring rod for relatively displacing elements attached to end mounts of the rod assembly comprises a housing having a rod member moveable between extended and retracted positions relative thereto, and a first compression spring in the housing surrounded by a second compression spring for biasing the rod member to one of an extended or retracted position relative to the housing. The two springs are oppositely wound, of different length, of different outside diameter, and of different wire diameter whereby, from a compressed condition, the spring rod exerts an expansion force which increases at a linear rate. Two sets of the springs can be arranged for biasing the rod member to a central position relative to the housing.
Patent NZ-534990-A (NZ)
Title: Heterocyclic amide derivatives as inhibitors of glycogen phosphorylase
Inventor: BIRCH ALAN MARTIN
IPC: A61P3/00
Filed: 2003-03-04
Abstract: Heterocyclic amide derivatives of formula 1 having glycogen phosphorylase inhibitory activity are described wherein: --- is a single or double bond; X is N or CH; R4 and R5 together are either -S-C(R6)=C(R7)- or -C(R7)=C(R6)-S-; R6 and R7 are independently selected from hydrogen, halo, nitro, cyano, hydroxy, fluoromethyl, difluoromethyl, trifluoromethyl, trifluoromethoxy, carboxy, carbamoyl, C1-4alkyl, C2-4alkenyl, C2-4alkynyl, C1-4alkoxy and C1-4alkanoyl; A is phenylene or heteroarylene; n is 0, 1 or 2; R1 is independently selected from halo, nitro, cyano, hydroxy, carboxy, carbamoyl, N-C1-4alkylcarbamoyl, N,N-(C1-4alkyl)2carbamoyl, sulphamoyl, N-C1-4alkylsulphamoyl, N,N-(C1-4alkyl)2sulphamoyl, -S(O)bC1-4alkyl (wherein b is 0, 1, or 2), C1-4alkyl, C2-4alkenyl, C2- 4alkynyl, C1-4alkoxy, C1-4alkanoyl, C1-4alkanoyloxy, hydroxyC1-4alkyl, fluoromethyl, difluoromethyl, trifluoromethyl and trifluoromethoxy ; or when n is 2, the two R1 groups, together with the carbon atoms of A to which they are attached, may form a 4 to 7 membered ring, optionally containing 1 or 2 heteroatoms independently selected from O, S and N, and optionally being substituted by one or two methyl groups; R2 is hydrogen, hydroxy or carboxy; R3 is selected from hydrogen, hydroxy, C1-4alkoxy, C1-4alkanoyl, carbamoyl, C3-7cycloalkyl (optionally substituted with 1 or 2 hydroxy groups), cyano(C1-4)alkyl, aryl, heterocyclyl, C1- 4alkyl (optionally substituted), and groups of the formulae B and B' wherein y is 0 or 1, t is 0, 1,2 or 3 and u is 1 or 2; provided that the hydroxy group is not a substituent on the ring carbon adjacent to the ring oxygen; with the proviso that the compound of formula (1) is not: (i) 2,3-dichloro-5-[N-2-oxo-1,2,3,4-tetrahydroquinol-3-yl)carbamoyl]-4H-thieno[3,4-b]pyrrole; (ii) 2-chloro-5-[N-(2-oxo-1,2,3,4-tetrahydroquinol-3-yl)carbamoyl]-6H-thieno[2,3- b]pyrrole; (iii) 2-chloro-5-[N-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinol-3-yl)carbamoyl]-6H- thieno [2, 3-b]pyrrole. Pharmaceutical compositions comprising the compounds are useful for treating type 2 diabetes, insulin resistance, syndrome X, hyperinsulinaemia, hyperglucagonaemia, cardiac ischemia and obesity
Patent NZ-537725-A (NZ)
Title: 6-Amino-1H-indazole and 4-aminobenzofuran compounds as phosphodiesterase 4 inhibitors
Inventor: SCHUMACHER RICHARD A
IPC: A61P29/00
Filed: 2003-07-18
Abstract: Disclosed is an aminobenzofuran of Formula II wherein R3, R4, R7 and R8 are as defined in the specification. Compounds of the type disclosed are phosphodiesterase 4 (PDE4) inhibitors and are useful for enhancing cognition, treating psychosis, treating memory impairment, treating allergies or inflammatory disease and treating neurodegeneration.
Patent NZ-541026-A (NZ)
Title: A method for reducing effects in industrial process waters of an extracellular enzyme produced by a collection of microorganisms attached to a surface in an industrial water environment
Inventor: BARAK AYALA
IPC: C02F1/68
Filed: 2002-08-05
Abstract: A method for reducing effects in industrial process waters of an extracellular enzyme produced by a collection of microorganisms attached to a surface in an industrial water environment, the method characterized by: causing a substance which is formed by the reaction of an oxidant and an amine source and which is capable of interfering with the production of an extracellular enzyme by a collection of microorganisms attached to a surface in an industrial water environment to contact a collection of microorganisms attached to a surface in an industrial water environment by intermittently feeding the substance in to the industrial water environment. During each feeding of intermittently feeding the substance is fed for a duration and at a concentration which is sufficient to substantially eliminate the production of the enzyme by the collection of the microorganism until the next feed in the intermittently feeding, but which is insufficient to inactivate the enzyme. (62) (62) Divided out of 530708
Patent NZ-545633-A (NZ)
Title: Pharmaceutical formulation comprising lanthanum compounds
Inventor: FERDINANDO JOSEPHINE CHRISTINE
IPC: A61K33/22
Filed: 2004-08-26
Abstract: Disclosed is a lanthanum carbonate pharmaceutical formulation in a chewable tablet comprising lanthanum carbonate in an amount from about 10 to about 40 % lanthanum, as the element, and a pharmaceutically acceptable excipient, produced by a process which comprises the steps of: a) blending the lanthanum carbonate and the pharmaceutically acceptable excipient to form a mixture; or b) blending the lanthanum carbonate and, the pharmaceutically acceptable excipient, compressing the resulting combination into a slug material or roller compacting the resulting combination into a strand material, and milling the prepared material into a free flowing mixture; and c) compressing the mixture formed in either of steps a) or b) into a tablet wherein the process is performed without wet granulation or drying.
Patent NZ-552345-A (NZ)
Title: Baking oven for bread, patisserie and pastries or similar
Inventor: VOEGTLIN RENE
IPC: A21B1/48
Filed: 2005-05-10
Abstract: Disclosed is a baking oven for bread, patisserie and pastry products. The baking oven includes at least one baking chamber which has a movable floor and a baking support. The baking oven further includes a radiant heating means with a floor hotplate positioned under the movable floor. The radiant heating means forms a closed-circuit convective circulation path with a heating fluid positioned in a space between the hotplate and the movable floor. The movable floor is permeable so as to allow heating by convection. The radiant heating means heats the products with the heating fluid via convection through the movable floor , without coming into contact with the baking chamber itself. The movable floor is supported by slides affixed to and extending above the floor hotplate so as to form channels suitable for convection of the heating fluid. The slides are oriented vertically substantially parallel to a direction of movement of the movable floor. The channels define the closed-circuit convective circulation path of the heating fluid and are parallel to the direction of movement of the movable floor.
Patent NZ-552929-A (NZ)
Title: System and method for managing medical databases for patient care devices
Inventor: BUTTERFIELD ROBERT D
IPC: A61B19/00
Filed: 2005-07-29
Abstract: A patient care system comprises a plurality of patient care devices (44, 46 and 48) capable of being programmed to operate in accordance with a specific behaviour. Each device includes a memory for storing at least one device-specific configuration dataset for controlling the patient care device in accordance with the specific behaviour. The patient care system also has an universal configuration database (84) containing operating information for a plurality of device behaviours; a processor (90) operatively connected to the universal configuration database and configured to load at least one device-specific configuration dataset associated with a selected device behaviour into the memory of at least one of the patient care devices to program the at least one patient care device in accordance with the operating information contained in the device-specific dataset and a communication system (30) operatively connecting each of the plurality of devices to the processor; and The system is further configured to provide each of the plurality of patient care devices with a device-specific configuration dataset from the universal configuration database.
Patent NZ-563245-A (NZ)
Title: Triazine compounds and compositions thereof for the treatment of cancers
Inventor: GAGNON LYNE
IPC: A61K31/53
Filed: 2006-05-19
Abstract: Disclosed herein are triazine compounds of formula I and compositions comprising said compound, wherein the substituents are as defined in the specification, useful in the treatment of metastatic melanoma and certain other cancers such as, prostate, breast, lung, colorectal, bladder, non-Hodgkin's lymphoma, uterine, melanoma, kidney, leukemia, ovarian and pancreatic cancers.
Patent NZ-564201-A (NZ)
Title: Beheading de-tailing and removing vertebrate nerve of fish
Inventor: YAMADA NAOKI
Filed: 2007-12-11
Abstract: The head of the fish is cut to severe the spinal cord of the live fish to kill the fish and the tail of the fish is cut to severe the spinal cord near the tail. A wire is then inserted into the spinal cord via the exposed ends and moved back and forth to destroy and remove the jelly like nerves and medulla oblongata. This process is said to assist delay in the stiffening and subsequent softening of the fish flesh. Instead of a wire, a jet of water or air may be shot through the spinal cord to remove the nerves.
Patent NZ-570766-A (NZ)
Title: Fire suppression system
Inventor: JOHNSON GARY L
IPC: A62C35/58
Filed: 2007-03-13
Abstract: Fire suppression apparatus 10 that includes at least one fire detector 24 and a sprinkler line 12. The sprinkler line 12 includes at least one thermoplastic conduit 14 containing fire suppression fluid, at least one thermally activated sprinkler with a predetermined fluid outlet and a flow control valve 20. The flow control valve is controlled by a fire detector 24 placed close to the sprinkler. The fire detector 24 opens the flow control valve 20 when it detects fire, which allows fluid to flow through the sprinkler line 12 to the outlet.
Patent NZ-582229-A (NZ)
Title: Carbohydrate-lipid constructs and their use in preventing or treating viral infection
Inventor: HENRY STEPHEN MICHAEL
IPC: A61K31/70
Filed: 2008-06-30
Abstract: Provided is the use of a carbohydrate-lipid construct of the formula F-S1-S2-L in the manufacture of a pharmaceutical preparation for inhibiting infection of the cells of a subject by a virus where: F is a glycotope of a ligand for one or more receptors expressed by the virus; S1 is 2-aminoethyl, 3-aminopropyl, 4-aminobutyl, or 5-aminopentyl; S2 is -CO(CH2)3CO-; -CO(CH2)4CO-; -CO(CH2)5CO- or -CO(CH2)5NHCO(CH2)5CO-; and L is a diacyl- or dialkyl-glycerophospholipid.
Patent NZ-586764-A (NZ)
Title: A high voltage three phase inverter and a high voltage DC-DC converter using cold cathode electron tubes.
Inventor: BIRNBACH CURTIS A
IPC: H02M7/533
Filed: 2009-01-23
Abstract: Disclosed is a high voltage inverter for converting DC power to AC power with three or more AC output phases. For each AC output phase the inverter has an AC input phase circuit (20) comprising first and second cold cathode field emission controllable electron tubes (30, 32) of triode, tetrode or pentode structure. Each electron tube (30, 32) is connected between an end of a primary transformer winding (48) and ground (28) with the centre tap (48a) of the primary winding connected to a DC potential in excess of 20 KV (26). The conduction state of the electron tubes is controlled so that the first and second electron tubes (30, 32) alternatively conduct so as to alternately bring the first and then second end of the primary winding approximately to the potential of ground. Each primary winding (48) is associated with a respective secondary winding of an AC output phase (12). Means are provided for adjusting the current in each individual AC output phase. A high voltage DC-DC converter using the same AC input phase circuit (20) is also disclosed.
Patent NZ-592503-A (NZ)
Title: Clip for convertible card row with a fixed section clippable to a display section wall and a two position rotatable section
Inventor: BERRY TODD E
IPC: A47F5/00
Filed: 2009-11-27
Abstract: 592503 A divider clip 36 for separating greeting cards within a row 20 of a display section 12 by receipt on a front wall thereof and for periodically supporting a convertible row 28 comprises a fixed portion and a rotatable portion. The fixed portion includes a clipping mechanism to couple the divider clip 36 with the front wall of the display section. The fixed portion is fixed in a generally vertical orientation when the clipping mechanism is coupled with the front wall of the display section. The rotatable portion is movably coupled with the fixed portion at a joint, where the rotatable portion is movable from a generally vertical orientation in a first position to a generally horizontal orientation in a second position with respect to the fixed portion. The rotatable portion is generally parallel to the fixed portion in the first position and is generally perpendicular to the fixed portion in the second position.
Patent NZ-594315-A (NZ)
Title: Antibody molecules having specificity for human ox40
Inventor: LAWSON ALASTAIR DAVID GRIFFITHS
IPC: A61K39/395
Filed: 2010-02-17
Abstract: 594315 Discloses an antibody which binds human OX40 comprising: CDR H1: NYGIH CDR H2: SISPSGGLTYYRDSVKG or SISPSGGLTYYRDSVEG CDR H3: GGEGIFDY CDR L1: RATQSIYNALA or RATEDIYNALA CDR L2: NANTLHT CDR L3 QQYYDYPLT For the treatment of allergies, COPD, asthma, autoimmune disease, or rheumatoid arthritis.
Patent NZ-597432-A (NZ)
Title: Oligonucleotide analogues incorporating 5-aza-cytosine therein
Inventor: PHIASIVONGSA PASIT
IPC: C12N15/11
Filed: 2006-09-25
Abstract: Patent No. 597432 Disclosed is a pharmaceutical composition comprising: 1) an isolated or synthetic dinucleotide analogue, its salt or ester, comprising one 5-aza-cytosine as a base residue in the sequence of the dinucleotide analogue, wherein the dinucleotide is linked with a phospholinker having only one phosphorus wherein the dinucleotide analogue has a general formula of: a. Z-L-G, or G-L-Z, wherein Z is 5-aza-cytosine; G is guanine; and L is a chemical linker covalently linking Z and G; or b. 5'-DpG-3' or 5'GpD-3', wherein D is decitabine; p is a phospholinker; and G is deoxyguanosine; and 2) a pharmaceutically-acceptable carrier, wherein the pharmaceutically-acceptable carrier comprises a combination of propylene glycol and glycerine.
Patent NZ-598242-A (NZ)
Title: Triazolopyridine compound, and action thereof as prolyl hydroxylase inhibitor and erythropoietin production inducer
Inventor: MATSUI TAKUYA
IPC: A61K31/437
Filed: 2010-07-16
Abstract: 598242 Disclosed is a compound represented by general formula [I] (wherein the symbols are as defined in the description), a pharmaceutically acceptable salt thereof or a solvate of the compound or salt; and a prolyl hydroxylase inhibitor and an erythropoietin production inducer, each containing the compound. The compound has a prolyl hydroxylase inhibitory action and erythropoietin production inducing activity, and is useful as an agent for prevention or treatment of various diseases and conditions (disorders) which are caused by a decrease in erythropoietin production.
Patent NZ-607615-A (NZ)
Title: Antibodies directed against il-17
Inventor: HORLICK ROBERT
IPC: C12P21/06
Filed: 2011-08-02
Abstract: Disclosed is an isolated IL-17-binding agent comprising both of the following: (a) an immunoglobulin heavy chain polypeptide comprising SEQ ID NO: 78, and (b) an immunoglobulin light chain polypeptide comprising SEQ ID NO: 24.   >24 EIVLTQSPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYGSSPLTFGGGTKVEIKR >78 EVQLVESGGGLVQPGGSLRLSCAASGFTFSNHWMNWVRQTPGKGLEWVAAINEDGSEKYYVGSVKVRFTISRDNAKNSLYLQMNSLRVEDTAVYYCARDYYDILTRDYYDILTDYYIHYWYFDLWGRGTLVTVSS