baber/WOPTO huggingface dataset:
Patent CY-1110929-T1 (CY)
Title: Παραγωγα πυριδαζινονης ως αγωνιστες υποδοχεων θυρεοειδικης ορμονης
Inventor: HAYNES NANCY-ELLEN
IPC: C07D403/12
Filed: 2010-11-22
Abstract: Στο παρόν έγγραφο παρέχονται συνθέσεις του τύπου (Ι) όπως επίσης και φαρμακευτικώς αποδεκτά άλατα αυτών, όπου οι υποκαταστάτες είναι αυτοί που αποκαλύπτονται στην περιγραφή. Αυτές οι ενώσεις, και οι φαρμακευτικές συνθέσεις που τις περιέχουν, είναι χρήσιμες για την θεραπευτική αγωγή νόσων όπως η παχυσαρκία, η υπερλιπιδαιμία, η υπερχοληστερολαιμία και ο διαβήτης και άλλες σχετικές διαταραχές και νόσοι και μπορεί να είναι χρήσιμες για άλλες νόσους όπως η NASH, η αθηροσκλήρωση, τα καρδιαγγειακά νοσήματα, ο υποθυρεοειδισμός, ο καρκίνος θυρεοειδούς και άλλες διαταραχές και νόσοι που σχετίζονται με αυτές.
Patent CY-1112306-T1 (CY)
Inventor: BERINGER REMI
IPC: B64C25/48
Filed: 2011-08-18
Abstract: The device includes a loading and non-compression locking mechanism for a master cylinder hydraulically connected to a hydraulic fuel tank and to braking members. The mechanism is dependent upon a control member capable of unlocking the mechanism in order to concomitantly urge the master cylinder to apply a predetermined hydraulic pressure for acting on the braking members.
Patent CY-1112010-T1 (CY)
Inventor: PENG GUANGHAO
IPC: C12N1/20
Filed: 2011-09-22
Abstract: An approach that uses heterotrophic ammonia oxidation bacteria (HAOE) in order to remove carbon and nitrogen pollutants in wastewater includes the cultivation of the heterotrophic bacteria in an activated sludge environment and then use of the above bacteria to remove carbon and nitrogen from the wastewater. According to the physiological characteristics of HAOB and the principles of combined oxidation of carbon and nitrogen, the approach is able to achieve simultaneous removal of carbon and nitrogen under the condition that the bacteria do not grow. The process is able to be carried out in the temperature range between 6 - 40°C. No excess sludge is produced in the process. The approach is able to control the process and product composition of aerobic ammonia oxidation through the control of organic carbon source, and is able to realize zero-accumulation of NO3--N in the nitrification process. The approach can fully utilize existing activated sludge systems to remove C and N. Therefore there is no need to build new facilities, and all C and N removal process can be finished in a single reactor.
Patent CY-1113419-T1 (CY)
Inventor: DE HEMPTINNE HERVÉ
IPC: A61K39/13
Filed: 2012-08-03
Abstract: The present invention relates to the field of vaccines for protecting against polio, and in particular to combination vaccines for protecting against polio, diphtheria, tetanus, and pertussis diseases. Specifically, vaccines comprising reduced dose inactivated poliovirus (IPV) is provided, which can maintain an adequate or improved level of protection against polio.
Patent CY-1114962-T1 (CY)
Title: Ανοσοδιαμορφωση χρησιμοποιωντας πλακουντιακα βλαστικα κυτταρα
Inventor: PALUDAN CASPER
IPC: C12N5/073
Filed: 2014-03-07
Abstract: Η παρούσα εφεύρεση παρέχει μεθόδους ανοσοδιαμόρφωσης χρησιμοποιώντας πλακουντιακά βλαστικά κύτταρα και πλακουντιακούς πληθυσμούς βλαστικών κυττάρων. Η εφεύρεση παρέχει επίσης μεθόδους παραγωγής και επιλογής πλακουντιακών κυττάρων και κυτταρικών πληθυσμών βάσει ανοσοδιαμόρφωσης, και συνθέσεων που περιλαμβάνουν τέτοια κύτταρα και κυτταρικούς πληθυσμούς.
Patent CY-1117250-T1 (CY)
Title: Λιξισενατιδη και μετφορμινη για τη θεραπευτικη αγωγη διαβητη τυπου 2
Inventor: RUUS PETER
IPC: A61K38/26
Filed: 2015-12-15
Abstract: Η παρούσα εφεύρεση αφορά έναν φαρμακευτικό συνδυασμό για τον γλυκαιμικό έλεγχο σε ασθενείς με διαβήτη τύπου 2. Αφορά τον συνδυασμό λιξισενατίδης (AVEOOIO), ενός αγωνιστή GLP-1, και μετφορμίνης.
Patent CY-1120076-T1 (CY)
Title: Μια κατασκευη μεταφορας, ενα συστημα μεταφορας και μια μεθοδος για την μεταφορα lng και/ή ηλεκτρικης ισχυος
Inventor: KNUTSEN DAVID MIKAL
IPC: B63B27/34
Filed: 2018-02-09
Abstract: Κοινοποιείται μία ημί-βυθιζόμενη κατασκευή μεταφοράς για την μεταφορά ενός υγρού μεταξύ μιας πλωτής κατασκευής και μιας πλωτής ή μη πλωτής εγκατάστασης και/ ή μεταφορά ηλεκτρικής ισχύος μεταξύ της πλωτής ή μη πλωτής εγκατάστασης και της πλωτής κατασκευής. Η κατασκευή μεταφοράς περιλαμβάνει τουλάχιστον ένα μέσο προσάρτησης της κατασκευής μεταφοράς για προσάρτηση με δυνατότητα αποδέσμευσης της κατασκευής μεταφοράς στην πλωτή κατασκευή, όπου το εν λόγω τουλάχιστον ένα μέσο προσάρτησης είναι παθητικά κινητά εγκατεστημένο σε σχέση με την κατασκευή μεταφοράς.
Patent CY-1121466-T1 (CY)
Title: Αντισωματα εναντι προσδεματων υποδοχεα β1 βραδυκινινης
Inventor: KOMINOS Dorothea
IPC: C07K7/18
Filed: 2018-06-14
Abstract: Η αποκάλυψη παρέχει αντισώματα που δεσμεύονται ειδικά σε Καλλιδίνη ή des-Arg10-Καλλιδίνη. Η αποκάλυψη παρέχει επίσης φαρμακευτικές συνθέσεις, καθώς και νουκλεϊκά οξέα που κωδικοποιούν αντισώματα αντι-Καλλιδίνης ή des-Arg10-Καλλιδίνης, ανασυνδυασμένους φορείς έκφρασης και κύτταρα ξενιστές για την παρασκευή τέτοιων αντισωμάτων, ή θραυσμάτων αυτών. Μέθοδοι χρήσης αντισωμάτων της αποκάλυψης για τη διαμόρφωση της δραστικότητας Καλλιδίνης ή des-Arg10-Καλλιδίνης ή για την ανίχνευση της Καλλιδίνης ή des-Arg10-Καλλιδίνης ή, είτε in vitro είτε in vivo, παρέχονται επίσης από την αποκάλυψη. Η αποκάλυψη παρέχει περαιτέρω μεθόδους παρασκευής αντισωμάτων που δεσμεύονται ειδικά σε πεπτίδιο τύπου des-Argg-Βραδυκινίνης και des-Arg10-Καλλιδίνης.
Patent CY-1120966-T1 (CY)
Title: Συσσωρευτης λιθιου
Inventor: PROCHAZKA JAN JR
IPC: H01M50/437
Filed: 2018-12-04
Abstract: Συσσωρευτής λιθίου με περίβλημα που περιλαμβάνει τουλάχιστον ένα στοιχείο με δύο ηλεκτρόδια (2a, 2b), εφοδιασμένα με συλλέκτες ρεύματος (3a, 3b) και διαχωρισμένα με διαχωριστή (4), όπου έκαστο ηλεκτρόδιο (2a, 2b), απαλλαγμένο από οργανικούς συνδέτες, συμπιέζεται σε αμφότερες πλευρές του συλλέκτη ρεύματος (3a, 3b) που είναι κατασκευασμένος από διάτρητη μεταλλική λωρίδα στη μορφή μεταλλικού πλέγματος, τεταμένου φύλλου μετάλλου ή διάτρητου φύλλου μετάλλου. Το ελάχιστο πάχος των ηλεκτροδίων (2a, 2b) είναι τρεις φορές το πάχος της διάτρητης μεταλλικής λωρίδας (3a, 3b).
Patent CY-1123087-T1 (CY)
Title: Συνθεση για τοπικη εφαρμογη με αντιμυκητιασικη δραση
Inventor: PANIN GIORGIO
IPC: A61K36/752
Filed: 2020-06-29
Abstract: Μια σύνθεση για τοπική εφαρμογή με αντιμυκητιασική δράση, που περιέχει αιθέριο έλαιο Melaleuca alternifolia, αιθέριο έλαιο ρίγανης, αιθέριο έλαιο μοσχολέμονου και έναν εστέρα βιταμίνης Ε, ο οποίος μπορεί να είναι, για παράδειγμα, οξική, n-προπιονική ή λινελαϊκή βιταμίνη Ε, και είναι κατά προτίμηση οξικό άλφα-τοκοφερύλιο • κατά προτίμηση, αυτά τα έλαια αποτελούν τουλάχιστον το 3% κατά βάρος της σύνθεσης και καθένα από αυτά απαρτίζει τουλάχιστον 1% κατά βάρος της σύνθεσης• κατά προτίμηση, η σύνθεση περιέχει από 10% έως 97% του αναφερθέντος εστέρα βιταμίνης Ε και μπορεί να αποτελείται από τα τρία προαναφερθέντα αιθέρια έλαια και τον εστέρα βιταμίνης Ε• εναλλακτικά, η σύνθεση μπορεί να έχει τη μορφή υδρόφοβης γέλης, που περιέχει 10 έως 50% του εστέρα βιταμίνης Ε, 20 έως 60% ενός φυτικού βουτύρου ή κεριού, από 10 έως 30% τριγλυκεριδίου καπρυλικού και καπρικού οξέος και από 5 έως 20% ενός πηκτωμοτογόνου παράγοντα για λιπίδια και τουλάχιστον 3% των προαναφερθέντων αιθέριων ελαίων, καθένα από τα οποία απαρτίζει τουλάχιστον το 1 % κατά βάρος της σύνθεσης.
Patent CY-1126052-T1 (CY)
Title: 1η-πυρρολο[2,3-c]πυριδιν-7(6η)-ονες και πυραζολο[3,4-c]πυριδιν-7(6η)- ονες ως αναστολεις των bet πρωτεϊνων
Inventor: COMBS ANDREW P
IPC: C07D471/04
Filed: 2023-05-18
Abstract: Η παρούσα εφεύρεση αφορά σε υποκατεστημένες πυρρολοπυριδινόνες και υποκατεστημένες πυραζολοπυριδινόνες οι οποίες είναι αναστολείς των BET πρωτεϊνών όπως BRD2, BRD3, BRD4 και BRD-t και είναι χρήσιμες στη θεραπεία ασθενειών όπως καρκίνου.
Patent GR-880300077-T1 (GR)
Title: Galanthamine or analogues thereof for treating alzheimer's disease
Inventor: DAVIS BONNIE M
IPC: A61K31/55
Filed: 1988-10-21
Abstract: Alzheimer's disease may be treated with galanthamine.
Patent HR-P20110184-T1 (HR)
Inventor: LOHSE OLIVIER
IPC: C07D215/26
Filed: 2011-03-14
Abstract: Postupak priprave 5-(α-haloacetil)-8-supstituirani oksi-(1H)-kinolin-2-ona, naznačen time, da obuhvaćaa)	reagiranjei)	8-hidroksi-(1H)-kinolin-2-ona s acilatnim agensom i Lewisovom kiselinom da se stvori 5-acetil-8-hidroksi-(1H)-kinolin-2-on; iliii)	8-hidroksi-(1H)-kinolin-2-ona s acilatnim agensom da se stvori 8-acetoksi-(1H)-kinolin-2-on, i obrađivanje, na samom mjestu, 8-acetoksi-(1H)-kinolin-2-ona s Lewisovom kiselinom da se stvori 5-acetil-8-hidroksi-(1H)-kinolin-2-on; b)	reagiranje 5-acetil-8-hidroksi-(1H)-kinolin-2-ona pripravljenog u koraku (a) sa spojem formule RL u prisutnosti baze i otapala, da se stvori 5-acetil-8-supstituirani oksi-(1H)-kinolin-2-on, pri čemu R je zaštitna skupina a L je izlazna skupina; ic)	reagiranje 5-acetil-8-supstituirani oksi-(1H)-kinolin-2-ona s halogenirajućim agensom u prisutnosti otapala da se stvori 5-(α-haloacetil)-8-supstituirani oksi-(1H)-kinolin-2-on. Patent sadrži još 13 patentnih zahtjeva.
Patent HR-P20120519-T1 (HR)
Title: Fountain filter
Inventor: RALF STUEKERJUERGEN
IPC: B01D29/46
Filed: 2012-06-20
Abstract: The well filter (1) has multiple annular filter discs (3) of plastic material placed on tie rods (2) running in axial direction to the well filter. The filter discs are made of styrene acrylonitrile. A portion of a glass fiber amounts to 20 to 40 percentages. The filter discs are made by process of injection molding.
Patent SI-1763636-T1 (SI)
Title: Roller pump
Inventor: BAUMANN MANFRED
IPC: F04B43/00
Filed: 2005-05-12
Abstract: The roller pump (1) consists of the state are with a pump bed (22) formed inside it, and a rotor (11) for contacting a curved tube (12), which is placed in the pump bed. The ends (16, 18) of this tube, which lead out of the pump, are laid across each other. There may be a connection piece by means of which the tube can be fixed in the roller pump.
Patent SI-2042795-T1 (SI)
Title: Watertight connection device, in particular for an air intake circuit of an automobile engine
Inventor: FAILLU JEAN-LUC
IPC: F16L17/00
Filed: 2008-09-23
Abstract: The device (101) has a set of lips to support on an internal endfitting and comprising a decoupling membrane (112). The membrane extends from a body (111) of an annular sealing joint (110) integrating with a boss (104) to radially slant towards interior of a non constrained state and terminating with a maximum radial thickness by a bead (112B). The bead is radially flattened against the endfitting with a contact pressure sufficient to seal the endfitting with reduced air pressure in an air intake circuit. The membrane absorbs the vibrations generated during use.
Patent TR-201109095-T1 (TR)
Title: Bir telekomünikasyon kule segmenti.
Inventor: PETER HAGER
IPC: B28B7/16
Filed: 2009-12-08
Abstract: Uzunlamasına yönde bölmelere (SI ila S4) ayrılmış olan uzunlamasına yapı (10) olup, bu yapı, bir taban segmentini (SI), en azından bir ara segmenti (S2, S3) ve bir uç kısım segmentini (S4) içermektedir, burada, segmentler, esas olarak, takviye edilmiş betonu içermektedir ve segmentler uzunlamasına yönde birden çok uzunlamasına tutturma elemanı (20) tarafından birbirine birleştirilmiştir; bu tutturma elemanları, uzunlamasına yönde boşluk bırakmadan taban segmentini uç kısım segmentine birleştiren bir uzunlamasına birbirine bağlantılı yapıyı (30) oluşturmaktadır ve burada, her bir segment, segmentin çeperinde oluşturulmuş ve tutturma elemanlarının bahsedilen segmente göre önceden belirlenen yapılandırmada tutulacağı şekilde düzenlenmiş bulunan tutturma elemanı kılavuz kısımlarını (50) içermektedir.
Patent DE-3685776-T2 (DE)
Inventor: CHOONG JOHN
IPC: A47C3/026
Filed: 1986-05-12
Granted: 1993-04-15
Abstract: The spring-tilt mechanism comprises a support frame (4), a seat portion (1) tiltable on the support frame (4) about a substantially horizontal axis (2) between a first and a second position, e.g. defined by stops (13, 13'). One end (15') of a torsion spring (15) is fixed against rotation in the support frame (4). A gear box (16) is operatively engaged with the other end (15'') of the torsion spring (15) and has an extendible member (24) engageable with a tracking surface (31) of the seat portion (1). An operating member (29) on the gear box (17) is easily accessible to a user sitting on the seat portion (1) to pre-load the torsion spring (15) for cushioning the user on the seat portion (1) between the said first and second positions (stops 13, 13').
Patent DE-3785610-T2 (DE)
Inventor: WEBB RODERICK PETER
IPC: G02F1/21
Filed: 1987-05-26
Granted: 1993-08-26
Abstract: An optically controlled selector comprises an optical coupler (1) having a first input (2) for an optical input signal, a second input (3) for an optical control signal and an output (4) for a combined signal, and a resonant cavity (5) downstream of the output of the coupler (1) and arranged to receive the combined signal. The resonant cavity (5) contains an optically non-linear material so that changes in the power of the optical control signal result in changes in the resonant frequency of the cavity (5). In use, the power of the optical control signal controls the transmission or suppression of the optical input signal through the optical cavity. Such a selector acts as a simple switch or to select one from a number of optical signals of different wavelength. Preferably the optical material is active and the optical cavity (5) formed by a semiconductor laser amplifier.
Patent DE-3789597-T2 (DE)
Inventor: GRAYSTON J
IPC: C12Q1/68
Filed: 1987-05-01
Granted: 1994-07-21
Abstract: Methods for detecting a unique strain of Chlamydia associated with acute respiratory disease. These methods utilize monoclonal antibody directed against an antigenic determinant of the TWAR organism, or DNA probes capable of specifically hybridizing to at least a portion of the DNA sequence of the TWAR organism. A method for determining the presence of antibodies to the TWAR organism, utilizing elementary bodies of the TWAR organism as antigen is also disclosed.
Patent DE-3877458-T2 (DE)
Inventor: DRIJFTHOLT JACOB
IPC: C11B3/00
Filed: 1988-07-15
Granted: 1993-08-19
Abstract: Method and apparatus for refining oil which in heated condition is used in the production of consumable products such as French fried patatoes by feeding by feeding the oil immeditately after starting the baking process through a filter system within the time within which free fat acids or fat acid oxydation products could be formed.
Patent DE-3879761-T2 (DE)
Inventor: FUJIOKA FAMIYU-TSUKAGUCHI
IPC: F26B5/16
Filed: 1988-05-27
Granted: 1993-10-07
Abstract: A method for drying a wetted molded product of pasty high viscous composition which comprises subjecting the molded product to a dehydration process while wholly or partially contacting the product with an open-cell foamed hydrophobic porous membrane.
Patent DE-3881909-T2 (DE)
Inventor: SWART WILHELMUS JOHANNES BERNA
IPC: A61B18/02
Filed: 1988-03-04
Granted: 1994-01-13
Abstract: Method and device for e.g. the removal of warts by local freezing with a liquid refrigerant applied upon the wart area by means of a hollow rod (9) of which one end (8) is connected to the pressure-reducing valve (3) of a container (1) which contains a refrigerant under the pressure of its own gas phase, such as dimethylether, whilst at the other end (10) of the hollow rod (9) a cotton wool bud (11) is present which is placed upon the wart area after having received a dosis of dimethylether thereby cooling the bud to e.g. - 50 DEG C.
Patent DE-60010850-T2 (DE)
Inventor: TRANI GIORGIO
IPC: B65B9/20
Filed: 2000-10-02
Granted: 2005-07-14
Abstract: A container made of flexible material with an inherently stable base and a method for manufacturing the container, the container being obtained in the shape of a pouch which has, in the region that will form the base, heat-sealed lateral regions and optionally ribbed guides which, by virtue of the very weight of the material that is introduced or by way of a punch, produce a base which makes the final container inherently stable.
Patent DE-60017811-T2 (DE)
Inventor: HOAG STEPHEN H
IPC: B01F13/06
Filed: 2000-01-07
Granted: 2006-01-12
Abstract: A method and apparatus for mixing bone cement (96) which produces bone cement (96) essentially free of entrained air. The apparatus includes a cartridge (30) having two telescoping cylinders (44,46). The outer cylinder (44) receives a cap (32) thereon which hermetically seals the cartridge (30). The cap (32) includes an outlet port (62) in which a break-away agitator (34) is installed and a port (60) for connection of a vacuum pump (24). In use, a desired vacuum pressure is drawn on the cartridge (30) and the inner cylinder (46) is allowed to be drawn into the outer cylinder (44) while the vacuum is being drawn, whereupon the inner cylinder (46) automatically stops moving relative to the outer cylinder (44) when the desired vacuum pressure is reached. Mixing of the bone cement (96) is then performed under the partial vacuum thereby created. The agitator paddles (74) provide a scraping action against both inner cylinder walls of the telescoping cylinders (44,46) thereby improving mixing. After mixing, the agitator (34) is broken away, an appropriate nozzle (36) is attached to the cartridge (30) and the cartridge (30) is inserted into a cement gun. The leading portion of the bone cement (96) develops a convex profile when axially advanced through the cartridge (30) and the piston plug (48) includes a tapered protrusion (92) which generally corresponds to the profile of the bone cement (96). The cap (32) and paddles (74) are also shaped correspondingly to the convex profile developed by the bone cement (96), resulting in substantially all of the bone cement (96) being squeezed from the cartridge (30). An air escape passage (66) is also provided to vent air contained within an annular gap between the agitator shaft (70) and the cap (32) upon initial expulsion of bone cement (96), resulting in the bone cement (96) expelled from the cartridge (30) being essentially free from entrained air.
Patent DE-60019162-T2 (DE)
Inventor: DEARN ALAN ROY
IPC: A61K31/422
Filed: 2000-11-28
Granted: 2006-02-02
Abstract: A pharmaceutical formulation of the 5HT1-agonist, zolmitriptan, for use in intranasal administration. The formulation is useful in treating migraine and related disorders.
Patent DE-60022626-T2 (DE)
Inventor: SKOELD ROLF
IPC: C10M173/02
Filed: 2000-01-13
Granted: 2006-06-22
Abstract: A method for the mechanical working of metals and alloys which comprises conducting the mechanical working in the presence of an aqueous cooling lubricant having a pH of 6-10 and containing a phosphate ester of the formula <?in-line-formulae description="In-line Formulae" end="lead"?>R<SUB>1</SUB>(oxyalkylene)<SUB>n</SUB>OP(O)(X)(OH) (I),<?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>or<?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>(HO)<SUB>2</SUB>(O)P-(oxyalkylene)<SUB>m</SUB>OP(O)(OH)<SUB>2</SUB> (II),<?in-line-formulae description="In-line Formulae" end="tail"?> where R<SUB>1 </SUB>is an alkyl group with 1-12 carbon atoms, oxyalkylene is a group containing 2-4 carbon atoms, n is a number from 1-20, X is hydroxyl, R<SUB>1</SUB>O or R<SUB>1</SUB>(oxyalkylene)<SUB>n</SUB>O, where R<SUB>1</SUB>, oxyalkylene and n have the meanings mentioned above, and m is a number from 4-40, or a salt thereof, and an alkenyl substituted succinic acid of the formula <?in-line-formulae description="In-line Formulae" end="lead"?>HOOCCH(R<SUB>2</SUB>)CH<SUB>2</SUB>COOH (III),<?in-line-formulae description="In-line Formulae" end="tail"?> where R<SUB>2 </SUB>is an alkenyl group with 4-10 carbon atoms, or a salt thereof, or a mixture of any of the compounds I, II and III.
Patent DE-60023591-T2 (DE)
Inventor: CHRISTENSEN PETER SEIER
IPC: C01B3/40
Filed: 2000-04-17
Granted: 2006-06-01
Abstract: Process for the preparation of hydrogen and carbon monoxide rich gas by steam reforming of a hydrocarbon feedstock in the presence of a steam reforming catalyst having a porous supporting structure, the structure is adhered to wall of a reforming reactor.
Patent DE-60025533-T2 (DE)
Inventor: CHATELAIN JEAN-LUC
IPC: G01V1/24
Filed: 2000-11-24
Granted: 2006-08-10
Abstract: A standalone digital data recorder of site background noise, by seismological transducer, providing at least data H and V in the form of analog signals, includes an acquisition and analog/digital conversion card, which includes at least two analog channels and a digital output, each analog channel including an input, a programmable gain analog signal amplifier and a filter, an analog multiplexer being provided between the filters and an analog/digital converter; a user interface; a removable storage device for storing data, a drive unit for an operating program, which includes a unit for enabling recording conditions, recording and warning of the end of the recording.
Patent DE-60028216-T2 (DE)
Inventor: DARROW L
IPC: C12N9/64
Filed: 2000-08-18
Granted: 2007-05-10
Abstract: Here we describe the molecular identification of a cDNA encoding a novel serine protease we have termed protease EOS. The deduced amino acid sequence, and it alignment with other well-characterized serine proteases indicates that it is a member of the S1 serine protease family. We have found that the protease EOS mRNA is expressed in platelets and leukocytes and more specifically eosinophils. Although this protease is abundantly expressed in ovary, retina and stomach, where it may perform important functions, its expression in platelets and certain cells of the immune system suggests that it may play roles in thrombosis and in the immune process. Enzymatically active protease EOS is amenable to further biochemical analyses for the identification of physiological substrates and specific modulators
Patent DE-60029069-T2 (DE)
Inventor: ANQUETIN ROBERT
IPC: B29C45/26
Filed: 2000-10-10
Granted: 2007-02-01
Abstract: The present invention relates to a plug (1) for fixing a screw (2) in a hole (3) along a longitudinal axis (6). The plug (1) comprises a body (7) having at least two expansion slots (20) and equipped with an external profile for fastening in the hole (3), in the form of a longitudinal alternation of portions (24, 25, 26, 27, 28) of which the longitudinal section does not have symmetry of revolution round the longitudinal axis (6) of the body (7) which are divided by slots (20) and are angularly offset from one another round the axis (6) so as to form transverse projections (38) relative to one another, which are mutually offset angularly round the axis (6). <IMAGE>