baber/WOPTO huggingface dataset:
Patent AU-681811-B2 (AU)
Title: Acetic anhydride activation for C-terminal protein sequencing
Inventor: BOYD VICTORIA L
IPC: G01N33/68
Filed: 1995-08-29
Granted: 1997-09-04
Abstract: A method is provided for C-terminal sequencing of a protein or peptide. An important feature of the method is the formation of an oxazolone moiety at the C-terminus of a protein or peptide by treatment with acetic anhydride under basic conditions followed by conversion of the oxazolone to a thiohydantoin moiety by treatment with thiocyanate under acidic conditions. Yields of thiohydantoin are further enhanced by delivering thiocyanate as the conjugate acid of a sterically hindered alkylammnonium cation.
Patent AU-617197-B2 (AU)
Title: Process for the synthesis of optically active aminoacids
Inventor: CALZOLARI CLAUDIO
IPC: C07C227/32
Filed: 1989-07-12
Granted: 1991-11-21
Abstract: New process for the synthesis of optically active aminoacids of formula <CHEM> wherein R and R1, equal or different,represent a hydrogen atom or an alkyl radical, straight or branched, containing from 1 to 6 carbon atoms, by reacting compounds of formula <CHEM> wherein R and R1 have the above seen meanings, R2 represent a nitrile group or a COR4 group wherein R4 represents hydroxy or halogen or alkoxy, straight or branched,containing from 1 to 6 carbon atoms,or a OCOR5 wherein R5 represents an alkyl or an alkoxy group, straight or branched, containing from 1 to 6 carbon atoms and R3 represents hydrogen, an alkyl or an alkoxy radical, straight or branched, containing from 1 to 6 carbon atoms or an aryl or aralkyl radical, with an optically active alcohol of formula  R6-OH      (III)  d or l wherein R6 represents an alkyl or cycloalkyl group, substituted or unsubstituted, containing from 3 to 12 carbon atoms, to obtain a pair of diastereoisomer esters of formula <CHEM> which is resolved in basic medium into the single diastereoisomer esters of formula <CHEM> from which the desired optically active aminoacid of formula (I) is obtained by treatment in acid medium.
Patent AU-616287-B2 (AU)
Title: Metered charge semi automatic production system
Inventor: SHIMROCK THOMAS
IPC: B01J37/02
Filed: 1989-07-18
Granted: 1991-10-24
Abstract: Method and apparatus for coating catalytic converter substrates with an exact amount of a precious metal. In the course of operation of the apparatus, a hollow substrate to be treated having opposed open ends is transferred from a starting location such that one end is lowered into a dip pan into which has been introduced a predetermined amount of slurry material containing the precious metal. With the one end immersed in the slurry, a vacuum placed on the other end of the substrate draws up the entire charge of slurry from the dip pan to coat the lower portion of the substrate. Thereafter, the substrate is raised from the dip pan. The vacuum continues to operate to cause the coating to be evenly distributed on all the interior surfaces of the substrate. Then the substrate is rotated and again lowered so that the other end is immersed in another predetermined charge of the slurry and the process is repeated. Thereupon, the substrate is again raised from the dip pan. Again, the vacuum continues to operate for a predetermined period of time to assure even distribution of the coating. Then the substrate is again rotated to its original orientation, and returned to its starting location.
Patent AU-567205-B2 (AU)
Title: 6a - carbaprostaglandins i2
Inventor: SKUBALLA WERNER
IPC: C07C405/00
Filed: 1985-02-11
Granted: 1987-11-12
Abstract: Carbacyclins of Formula I    <IMAGE>  (I)  wherein R1 is an alkyl, cycloalkyl, aryl, aralkyl, or heterocyclic group, Y is a keto group or a hydroxymethylene group, X is a -CH2- group or an oxygen atom, A is a -CH2-CH2-, a trans-CH=CH- or a -C 3BOND C- group, W is a hydroxymethylene group or a   <IMAGE>  D is the group   <IMAGE>   a straight-chain or branched, saturated alkylene group or unsaturated alkylene group of up to 5 carbon atoms which can optionally be substituted by 1-2 fluorine atoms, n is 1, 2 or 3, E is a direct bond, a -C 3BOND C- group or a -CR4=CR5- group wherein R4 is hydrogen or an alkyl group and R5 is hydrogen, halogen or an alkyl group, R2 is an alkyl, cycloalkyl, aryl, or heterocyclic group, and R3 is a hydroxy group, are valuable, e.g., as cytoprotective agents.
Patent AU-569609-B2 (AU)
Title: Preparation of 1-alkyl-3,5-diphenylpyrazoles
Inventor: MAULDING DONALD ROY
IPC: C07D231/12
Filed: 1985-03-04
Granted: 1988-02-11
Abstract: This application relates to a process for the preparation of substituted and unsubstituted 1-alkyl-3,5- diphenylpyrazole compounds by reacting a 3,5-diphenyl (substituted or unsubstituted) pyrazole with an excess of dialkyl sulfate, in the presence of aqueous alkali hydroxide and a quaternary ammonium phase transfer catalyst.
Patent AU-576558-B2 (AU)
Title: Water heater construction
Inventor: VAGO OTTO Z
IPC: F24H9/14
Filed: 1985-03-06
Granted: 1988-09-01
Abstract: A water heater (10) having a tank wall (12) and a bottom head (14) welded to the wall to provide a liquid tight chamber (16) therein. The bottom head has an upwardly directed circular flange (32) with a central opening therein. The flange (32) is connected to a flue tube in a unique manner. The connection between the flange (32) on the lower head and the flue tube (28) is accomplished by press-fitting the flange into the end of the tube and then welding the two parts together by a weld between the end of the tube and the outer surface of the flange (32).
Patent AU-634488-B2 (AU)
Title: Pyridazinone manufacture
IPC: C07D237/24
Filed: 1989-09-13
Granted: 1993-02-25
Abstract: Improved method for the manufacture of plant regulant pyridazine-4-one carboxylic acids, which comprises the step of decarboxylating a 4-oxo-3, 5-pyridazine dicarboxylic acid to give a 4-oxo-5-pyridazine carboxylic acid by treatment with 95-100% sulphuric acid at 160 DEG C-180 DEG C using a reactant: acid weight ratio of about 1:4 to 1:10.
Patent AU-636305-B2 (AU)
Title: Solar control layered coating for glass windows
IPC: B32B7/023
Filed: 1989-08-24
Granted: 1993-04-29
Abstract: A five-layer coating, commonly called a "stack", for glass windows in order to control the proportion of solar radiation permitted to pass through the window, the remainder being reflected by the coating, while maintaining a desired visible light characteristic transmission. Particularly, the technique is applied to vehicle glass windows, such as truck and automobile windshields, where the amount of solar radiation allowed to pass into the vehicle through the window is minimized within the constraints of maintaining visible light transmission above a certain legal level. The characteristics of the coating are also selected for visible light reflected from the window to the outside to be a substantially neutral color, highly desirable for the overall appearance of trucks and automobiles.
Patent AU-673530-B2 (AU)
Title: Use of compounds which absorb and/or fluoresce in the I/R range as markers for liquids
Inventor: ALBERT BERNHARD
IPC: C09K11/06
Filed: 1993-07-13
Granted: 1996-11-14
Abstract: Use of compounds from the class of the phthalocyanines, naphthalocyanines, nickel dithiolene complexes, aminium compounds of aromatic amines, methine dyes or azulenesquaric acid dyes which have their absorption maximum in the range from 600 to 1,200 nm and/or a fluorescence maximum in the range from 620 to 1,200 nm, as markers for liquids, a process for detecting markers in liquids, and a detector suitable for this purpose.
Patent AU-580321-B2 (AU)
Title: New tryptamine derivatives, a process for their preparation, and their use
Inventor: GLASER THOMAS
IPC: A61K31/40
Filed: 1985-08-09
Granted: 1989-01-12
Abstract: Novel tryptamines of the formula   <IMAGE>   in which X is an alkylene chain or 2 to 4 carbon atoms wherein a carbon atom may be replaced by O or N-lower alkyl, and wherein a carbon atoms may be substituted by lower alkyl, R is hydrogen, lower alkyl, lower alkoxy, phenyl-lower alkyl, phenyl-lower alkoxy, hydroxy, amino-lower alkyl, fluorine, chlorine, bromine, cyano, carbamoyl or azido, R1, R2, R3 and R4 each independently is hydrogen or lower alkyl, R5 is hydrogen, R6-CO- or R6-SO2-, and R6 is amino, lower alkoxy, phenyl or lower alkyl-phenyl, or dimers or salts thereof, are effective in treating disorders of the central nervous system.
Patent AU-630643-B2 (AU)
Title: Functional recombinantly prepared synthetic protein polymer
Inventor: CAPPELLO JOSEPH
IPC: C07K14/00
Filed: 1989-11-07
Granted: 1992-11-05
Abstract: Novel polymers are provided which are produced by recombinant techniques. The polymers are characterized by having a small repeating sequence which provides for strands capable of associating, resulting in useful structural characteristics, where the strands are joined by turns or loops which are flexible and available for interaction with the environment. Specifically, repeating groups of naturally occurring proteins such as silk are modified by introduction of an amino-acid sequence at a site which provides for a turn between strands to provide for readily available oligopeptides capable of interacting with molecules in the environment.
Patent AU-638439-B2 (AU)
Title: Whey protein composition, a method for producing it and application of the whey protein composition
IPC: A61K35/20
Filed: 1989-12-12
Granted: 1993-07-01
Abstract: The invention relates to a biologically active whey protein composition comprising substantive amounts of a whey protein concentrate comprising a whey protein isolated mixture having protein and/or peptide components containing glutamylcysteine groups wherein said components are present in an essentially undenatured state and wherein the biological activity of the whey protein concentrate is restricted to its undenatured conformation, a method of producing a biological active whey protein concentrate composition comprising the following steps:   a) immediately after milking cooling the milk to a temperature in the range of 2 DEG C to 10 DEG C, especially to 4 DEG C, and removing contaminants, b) after another cleaning of the milk, precipitation of the curd by reducing the pH to about 4.6 with lactic acid initially at 20 DEG C, c) addition of rennet and raising the temperature to about 30 DEG C for 20 minutes to promote expulsion of whey from the curd, allowing the agitation in a vat to resolve at low speed, d) thermal treatment of the pasteurization type of the remaining product in the vat and agitating at high speed, for cheese production,   e) irradiation and separation of the whey and f) ultrafiltration of the whey using a membrane having a molecular weight cut off of substantially 10,000 or less, or g) ultrafiltration of the whey using a membrane having a molecular weight cut off of substantially 17,000 or less to retain  beta -lactoglobulin and serum albumin, wherein the fraction of whey protein concentrate is not heated and the material from which it is derived is slowly agitated to minimize protein denaturation and that said ultrafiltration is carried out in a production line comprising up to 20 frame-type modules holding a large number of said membranes achieving a final undenatured protein concentrate in dry matter, wherein said ultrafiltration is carried out at a temperature in the range of 4 DEG C to 20 DEG C, especially at 4 DEG C.
Patent AU-642856-B2 (AU)
Title: Naphthalene derivatives
Inventor: OKITA MAKOTO
IPC: C07C49/83
Filed: 1989-12-14
Granted: 1993-11-04
Abstract: A naphthalene derivative having the formula is new and useful for medicine. <CHEM> [wherein R<1> represents a hydrogen atom, a lower alkyl group or an acyl group; R<2> independently represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, a halogen atom, a cycloalkyl group, a cycloalkylalkyl group, a hydroxyl group, an aryl group which may be substituted, an arylalkyl group whose aryl group may be substituted, a heteroaryl group, or a heteroarylalkyl group; R<3> and R<4> are the same or different and represent a hydrogen atom, a lower alkyl group, a lower alkenyl group, an aryl group which may be substituent, an arylalkyl group whose aryl group may be substituted, an arylalkenyl group whose aryl group may be substituted, a cycloalkyl group, an alkoxyalkyl group, a heteroaryl group, a heteroarylalkyl group, a carboxyl group, a carboxyalkyl group, an aminoalkyl group, or a cyano group; R<5> represents a group of the formula, -OR<7>, (wherein R<7> represents a hydrogen atom or a lower alkyl group), or a group of the formula, <CHEM> (wherein R<8> and R<9> are the same or different and represent a hydrogen atom or alower alkyl group or R<8> and R<9> can form, along with the nitrogen atom bonded with R<8> and R<9>, a ring which may contain an oxygen atom); R<6> independently represents a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group, a hydroxyl group, an amino group, an arylalkyl group, or an aryl group; and m is 0 or an integer of from 1 to 2, and n is 0 or an integer of from 1 to 4.]
Patent AU-627537-B2 (AU)
Title: Pressure washer with spring-less outlet to inlet bypass
Inventor: PAIGE CLIVE R
IPC: F04B49/24
Filed: 1990-01-15
Granted: 1992-08-27
Abstract: A pressure washer (10) for delivering a liquid under high pressure has an inlet conduit (30) connected to a liquid supply and an outlet conduit (50) coupled to a spray nozzle (18) which can be operated to control the delivery of liquid through the spray nozzle (18). Liquid, e.g., water, is pumped from the inlet (30) to the outlet conduit (50), elevating its pressure significantly. A bypass conduit (56) enables recirculation of the liquid from the outlet (50) to the inlet conduit (30). A bypass system (14), disposed between the outlet conduit (50) and the bypass conduit (56), includes a shuttle valve (70) which moves between first and second positions at which it respectively blocks or opens the liquid path from the outlet conduit (50) to the bypass conduit (56). The shuttle (70) is such that, when the liquid pressure on the side of the shuttle (70) facing the spray nozzle (18) is approximately equal to or greater than the liquid pressure in the outlet conduit (50), the shuttle (70) moves to a position which unblocks the bypass conduit (56), approximately equalizing the pressure across the shuttle (70) and protecting the washer's (10) components and enhancing its operability. A nozzle seal arrangement in the pressure washer's pump (12) comprises a pair of seals (230,236) between each piston (190) and cylinder (32) wall of the pump (12). One of the seals pivots in response to side to side wobbling of the piston (190) while maintaining proper sealing conditions.
Patent AU-730427-B2 (AU)
Title: Encapsulation of polypeptides within the starch matrix
Inventor: KEELING PETER
IPC: C12N1/21
Filed: 1997-09-30
Granted: 2001-03-08
Abstract: The present invention relates to a recombinant nucleic acid encoding a hybrid polypeptide which comprises a transit peptide for the translocation of the polypeptide into an appropriate organelles such as plastids, a starch-encapsulating region from maize starch synthase and a payload polypeptide, wherein said payload polypeptide can be either N- or C-terminal to the starch encapsulating region. The invention also relates to the expression vectors comprising said nucleic acid, and hosts comprising the said vector. Also, the invention encompasses methods of producing the hybrid polypeptide thereof from starch and particularly from starch granules, and industrial uses of the payload polypeptide recombinantly produced in said hybrid polypeptide wherein said payload polypeptide is a biologically active molecule.
Patent AU-709111-B2 (AU)
Title: DNA molecules, preparation and use in gene therapy
Inventor: CAMERON BEATRICE
IPC: C12Q1/6839
Filed: 1996-02-21
Granted: 1999-08-19
Abstract: Double-stranded DNA molecules characterised in that they are circular and in that they essentially include one or more genes of interest.
Patent AU-713926-B2 (AU)
Title: Kitchen appliance
Inventor: BORGER GEORG
IPC: A47J43/046
Filed: 1997-10-22
Granted: 1999-12-16
Abstract: The invention concerns a kitchen appliance comprising an electric drive motor (9) which is disposed in a housing (1, 3, 4) substantially perpendicular to the surface on which said appliance stands. The drive motor (9) is surrounded by a housing part (3), ventilation apertures (13, 14) being formed in the housing (1, 3, 4). The drive motor (9) is not provided with fan wheels. Viewed in the longitudinal extension (X) of the drive motor (9), the ventilation apertures (13, 14) are disposed substantially in the region of the opposite ends of the housing part (3). The ventilation aperture (14) through which the hot air (18) is discharged is disposed above the drive motor (9). As a result, even without fan wheels, an air flow is produced by convection from the air inlet apertures (13) to the air outlet apertures (14), so rendering the appliance more economical and quieter yet providing adequate cooling of the drive motor (9).
Patent AU-586995-B2 (AU)
Title: Apparatus for electrical resistance seam welding by rollers and electrode roller and welding-current supply particularly provided therefor
Inventor: PORTMANN NIKLAUS
IPC: H01R39/64
Filed: 1985-11-20
Granted: 1989-08-03
Abstract: The apparatus described is so constructed that narrow can bodies having an internal diameter of 52 mm for example can be produced from rounded blanks by welding the edges of the blanks. The supply of welding current to the electrode roller is effected through copper caps, a clamping member, contact members disposed at each side thereof, contact jaws silver contact segments and peripheral surfaces of wide hubs which are provided on the electrode roller. The contact jaws engage the hubs of the electrode roller at both sides of the roller from above and below, as a result of which there is a large area for the transmission of current and a low specific contact pressure. The hub surfaces, which form the actual contact surfaces of the electrode roller, are continuously lubricated through felt lubricating segments. The contact pressure of the contact jaws can be adjusted in a simple manner by means of a screw. The whole apparatus and particularly the electrode roller are extensively cooled internally by a special cooling device.
Patent AU-699086-B2 (AU)
Title: Improved method and reagent composition for performing leukocyte differential counts on fresh and aged whole blood samples
Inventor: MALIN MICHAEL J
IPC: G01N15/14
Filed: 1996-05-13
Granted: 1998-11-19
Abstract: The present invention provides an improved reagent composition and method to perform white blood cell differential counting and subpopulation analysis using both fresh and aged blood samples with accuracy and precision. The invention is particularly applicable for the analysis of aged blood samples that have been stored at room temperature for over a day, thereby allowing accurate and useful information to be obtained from samples that are normally considered to be suboptimal. The improved reagent composition and method are particularly related to the peroxidase method of white blood cell differential determinations. One aspect of the invention includes an improved aqueous reagent composition for carrying out the peroxidase method of differential counting. Another aspect includes the use of a rinse cycle and rinse solution devoid of hemolytic surfactant to alleviate the adverse effects of rinse carryover and to streamline and economize the analytical process, particularly when the analyses are performed on automated hematology analyzers and flow cytometry systems. The composition and method of the invention provide clinically useful data for the differential analysis of whole blood samples.
Patent AU-698852-B2 (AU)
Title: Sensor
Inventor: HIGSON SEAMUS PATRICK JOHN
IPC: G01N27/02
Filed: 1996-04-18
Granted: 1998-11-12
Abstract: PCT No. PCT/GB96/00922 Sec. 371 Date Oct. 17, 1997 Sec. 102(e) Date Oct. 17, 1997 PCT Filed Apr. 18, 1996 PCT Pub. No. WO96/33403 PCT Pub. Date Oct. 24, 1996There is disclosed a sensor for an analyte comprising a working electrode assembly, itself comprising a micro-electrode array in which each micro-electrode is coated with a layer of redox state dependent conducting organic polymer, a counter electrode; a conductive medium containment into which the electrodes are disposed and a material for analysis may be introduced; means for applying an alternating electric polarizing potential across the electrodes; and means for detecting a variation in a conductimetric property across the {working electrode->counter electrode} plane in the presence of the analyte.
Patent AU-773668-B2 (AU)
Title: Compounds as selective agonists at alpha 2B or 2B/2C adrenergic receptors
Inventor: CHOW KEN
IPC: A61K31/421
Filed: 2000-06-08
Granted: 2004-06-03
Abstract: Compounds having adrenergic activity which are a selective agonists for one or both of the  alpha 2B and  alpha 2C adrenoceptor receptor subtypes in prefrence to the  alpha 2A adrenoceptor receptor subtype; the active compound being selected from the group consisting of compounds having formula (I) wherein the dotted lines represent optional bonds; R is H or lower alkyl; X is S or C(H)R<1>, wherein R<1> is H or lower alkyl, Y is O, N, S, (CR<1>2)y, wherein y is an integer of from 1 to 3, -CH=CH- or -Y<1>CH2-, wherein Y<1> is O, N or S.
Patent AU-723396-B2 (AU)
Title: Food product and process
Inventor: MCLACHLAN CORRAN NORMAN STUART
IPC: A23L13/20
Filed: 1996-05-09
Granted: 2000-08-24
Abstract: A milk or other dairy product, capable of minimising the onset of disease such as coronary heart disease or enhancing the immune response is derived from animals which are substantially free of the  beta -casein A<1> allele. Bulk milk can be produced by testing for and culling cows who test positive for the  beta -casein A<1> allele, or by producing immunoglobulins and other immune response proteins, in cow's milk from animals not possessing the  beta -casein A<1> allele, or other commercial milk pruducing animals, to this allele, to counteract the immunosuppressant substances present that are produced from it, in commercial milking cows such as Holsteins, together with its blending with non-treated milk or the recovery of such immunoproteins.
Patent AU-776825-B2 (AU)
Title: Molecules designated LDCAM
Inventor: BAUM PETER ROBERT
IPC: C07K19/00
Filed: 1999-08-05
Granted: 2004-09-23
Abstract: The invention is directed to LDCAM as a purified and isolated protein, the DNA encoding the LDCAM, host cells transfected with cDNAs encoding LDCAM, processes for preparing LDCAM polypeptides and compositions and methods for treating utilizing LDCAM polypeptides.
Patent AU-644320-B2 (AU)
Title: Coupon inserting apparatus and method
Inventor: KOTSIOPOULOS THOMAS GEORGE
IPC: B65B61/20
Filed: 1990-05-04
Granted: 1993-12-02
Abstract: Apparatus (5) that uses the burster method for positioning coupons from a continuous web (46) at a predetermined time at a predetermined location for insertion is disclosed. Positioning rolls (48, 50) define a bight to receive the leading edge of a coupon (20) and are driven by positioning drive mechanism (58) at a continuous predetermined speed. Feeding roll mechanism (36, 38) located upstream of the positioning rolls (48, 50) in the excess of one coupon length are driven by intermittent feeding drive (56) at a speed substantially less than the speed of the positioning rolls (48, 50). Controller (70) actuates and deactuates the feeding drive mechanism (56) in response to timing device (24, 26) related to the position of a container (10) and coupon sensing device (62) at a sensing position between the positioning rolls (48, 50) and the feeding roll mechanism (36, 38).