baber/WOPTO huggingface dataset:
Patent EP-0678522-A1 (EP)
Inventor: CHANCE RONALD EUGENE
IPC: A61K/
Filed: 1990-02-06
Abstract: Analogs of human insulin modified at position 29 of the B chain thereof and, optionally, at other positions, have modified physico-chemical and pharmacokinetic properties and are useful in the treatment of hyperglycemia. The insulin analogs are of the formula   
 or a pharmaceutically acceptable salt thereof, wherein A21 is alanine, asparagine, aspartic acid, glutamine, glutamic acid, glycine, threonine, or serine; B1 is phenylalanine, aspartic acid, or is absent; B2 is valine or may be absent when B1 is absent; B3 is asparagine or aspartic acid; B9 is serine or aspartic acid; B10 is histidine or aspartic acid; B27 is threonine or is absent; B28 is any amino acid, B29 is L-proline, D-proline, D-hydroxyproline, L-hydroxyproline, L-(N-methyllysine), D-lysine, L-(N-methylarginine) or D-arginine; B30 is alanine, threonine or is absent; Z is -OH, -NH₂, -OCH₃, or -OCH₂CH₃; X is Arg, Arg-Arg, Lys, Lys-Lys, Arg-Lys, Lys-Arg, or is absent; and Y may be present only when X is present and, if present, is Glu or an amino acid sequence which comprises all or a portion of the sequence   
 and which begins at the N-terminus Glu of such sequence; 
provided that when A21 is asparagine, B1 is phenylalanine, B2 is valine, B3 is asparagine, B9 is serine, B10 is histidine, B27 is threonine, B28 is lysine, B29 is L-proline, B30 is threonine, X is absent and Y is absent, then Z is -NH₂, -OCH₃ or -OCH₂CH₃.
Patent EP-0714650-A1 (EP)
Inventor: FRAJDENRAJCH JEAN
IPC: A61H15/00
Filed: 1995-11-17
Abstract: The massager consists of a motor with a drive shaft (15) to rotate a massaging head (26) carrying the massaging elements. The massaging head has a central channel (27) for fitting onto the motor shaft and supports (22,19) for linking the two. The supports are in the form of upper (22) and lower (19) stops which allow a relative axial movement of the massaging head and shaft, while the axial channel (27) in the head and the shaft are shaped to allow the head to be disposed at various angles to the shaft. Radial and axial elastic thrust elements (20,21) hold the massaging head in a stable position and to allow its angular and axial movements.
Patent EP-0688829-A1 (EP)
Inventor: HIRAYAMA AKIRA
IPC: C09B5/48
Filed: 1995-06-09
Abstract: 1-Aminoanthraquinone is suspended in a solvent mixture composed of an aprotic polar solvent and water in a weight ratio ranging from 80 :20 to 99 :1, and reacted by adding an alkaline condensing agent to the suspension. Thus, high-quality dianthraquinone-N,N'-dihydroazine having a very low impurity content can be produced in high yield.
Patent EP-0712138-A1 (EP)
Inventor: BALL RUSSELL M
IPC: G21C1/30
Filed: 1995-09-08
Abstract: An arrangement for transferring energy in a medical isotope production reactor comprises a liquid pool (15) and a liquid reactor core disposed within a vessel (10) immersed in the pool (15). The vessel wall (12) defines a reactive area and houses a fuel solution (25). The fuel solution (25) flows within the reactive area transporting the energy to the vessel wall (12). Heat transfer enhancers such as fins (30), tubes (14), rods or bars may extend from the inner and outer surfaces of the vessel wall (12) to add heat transfer surface and improve the heat transfer from the fuel solution (25) to the liquid pool (15). Baffles (18) may be added to the heat transfer enhancers to facilitate the flow of fluid.
Patent EP-0671791-A1 (EP)
Inventor: LESTERLIN DOMINIQUE
IPC: H01S5/026
Filed: 1995-03-10
Abstract: The modulator includes an optical guide (2) made of a semiconductor substrate (3) with an angled output surface covered by antireflective coating. Three electrodes are placed opposite the guide and connected to an electric field generator (4). An input signal (T) is applied to the generator which in turn generates a variable electric field in the electrodes. An optical link which uses the modulator includes a light source (50) coupled to the modulator (52) and an optical fibre (54). A receiver (56) collects the output wave from the fibre and generates an output signal (S).
Patent EP-0695696-A1 (EP)
Inventor: FAVRE BERNARD
IPC: B65D35/22
Filed: 1995-07-31
Abstract: The container/dispenser is made with a deformable wall and two separate compartments (4,4') for different liquids or fluids, connected to one dispensing head. The container is oval in shape, with the two compartments formed in the ends of the oval and a deformable free space (5) between them. The container is made from an elastically deformable material, translucent or semi-translucent, with the free space deformed under manual pressure. Air escapes through a hole provided for the purpose.
Patent EP-0711912-A1 (EP)
Inventor: FERRI PASCAL
IPC: F02D41/22
Filed: 1995-11-10
Abstract: The procedure for controlling the supply of fuel to a fuel injected engine (1) with controlled ignition involves the use of an oxygen probe (11) fitted in the exhaust line (3). This probe is used in a control loop regulating the ratio of air and fuel admitted to the engine. The signal delivered by the oxygen probe is analysed in order to determine from it the appearance of any fault in the supply of fuel to the engine. Such a fault becomes apparent if the number of occasions on which the fuel mixture is weakened exceeds a given threshold.
Patent EP-0743983-A1 (EP)
Inventor: KELNER GREGORY S
IPC: C07K16/24
Filed: 1995-02-07
Abstract: Nucleic acids encoding a thymokine from a mammal, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
Patent EP-0744902-A1 (EP)
Title: Sports drink
Inventor: KING RODERICK F G JOSEPH
IPC: A23L2/00
Filed: 1995-02-16
Abstract: PCT No. PCT/GB95/00331 Sec. 371 Date Nov. 1, 1996 Sec. 102(e) Date Nov. 1, 1996 PCT Filed Feb. 16, 1995 PCT Pub. No. WO95/22260 PCT Pub. Date Aug. 24, 1995A sports drink comprises an aqueous solution including a saccharide selected from: galactose, a galactose containing disaccharide or oligosaccharide, sorbitol, lactose, fructose or mixtures thereof and optionally including not more than 1.25% w/v of glucose.
Patent EP-0704097-A1 (EP)
Inventor: HENKE TORSTEN
IPC: H01F7/18
Filed: 1995-03-24
Abstract: Un procédé et un dispositif servent à commander un consommateur électromagnétique (100), notamment une vanne magnétique de commande de la quantité de carburant à injecter. Un élément accumulateur d'énergie (145) est monté entre un demi-pont et une source de tension (Ubat).
Patent EP-0752860-A1 (EP)
Inventor: UPASANI RAVINDRA B
IPC: C07J7/00
Filed: 1995-02-14
Abstract: Methods, compositions and compounds for modulating the GABAA receptor-chloride ionophore complex to alleviate stress, anxiety, seizures, mood disorders, PMS and PND and to induce anesthesia.
Patent EP-0706174-A1 (EP)
Inventor: OSHIMA MITSUAKI
IPC: G06F1/00
Filed: 1995-04-18
Abstract: In a recording/reproducing apparatus in which reproduction of information is carried out by using an optical recording medium, the physical characteristics of a ROM disk are extracted and enciphered, and the resultant ciphers are recorded on the optical disk. In order to reproduce the information, the physical characteristics obtained by deciphering these ciphers and physical characteristics information detected from the ROM disk are compared with each other. When they do not agree, the use of an illegally duplicated disk is inhibited by stopping the operation of the apparatus. A duplicated medium is detected by reproducing the physical characteristics information, which have been recorded in a magnetic recording layer (4) in an optical recording medium (2), by a magnetic head (8), and comparing this reproduced information with the information determined by a physical characteristics information detecting means.
Patent EP-0754192-A1 (EP)
Inventor: PASTAN IRA
IPC: A61K47/48
Filed: 1995-04-07
Abstract: PCT No. PCT/US95/04468 Sec. 371 Date Jan. 8, 1997 Sec. 102(e) Date Jan. 8, 1997 PCT Filed Apr. 6, 1995 PCT Pub. No. WO95/27732 PCT Pub. Date Oct. 19, 1995The present invention provides for circularly permuted ligands which possess specificity and binding affinity comparable to or greater than the specificity and binding affinity of the original (unpermuted) ligand. The invention further provides for novel chimeric molecules comprising a circularly permuted ligand joined to one or more molecules of interest.
Patent EP-0767644-A1 (EP)
Inventor: CLARK TRACEY A
IPC: A61F13/15
Filed: 1995-04-12
Abstract: A multilayered absorbent feminine hygiene product which is configured for releasable attachment to a user's garment has a plurality of absorbent pads. Each of the absorbent pads has an absorbent layer to contain absorbed fluid and a barrier layer to prevent absorbed fluid from leaking completely through the individual pad. The first, lowermost pad in the product is configured for releasable attachment to a user's garment. Additional pads in the product are releasably attached above the first pad to form a stacked or layered product. The pads may be adhesively, thermally, compressively, or mechnically bonded. Preferably, the multilayered product includes three absorbent pads.
Patent EP-0758317-A1 (EP)
Inventor: ZELLER MARTIN
IPC: C07C311/20
Filed: 1995-04-22
Abstract: alpha -Amino acid amides of the formula I    <IMAGE>  I  in which n is the number zero or one; R1 is C1-C12alkyl, which is unsubstituted or can be substituted by C1-C4alkoxy, C1-C4alkylthio, C1-C4alkylsulfonyl, C3-C8cycloalkyl, cyano, C1-C6alkoxycarbonyl, C3-C6alkenyloxycarbonyl or C3-C6alkynyloxycarbonyl; C3-C8cycloalkyl; C2-C12alkenyl; C2-C12alkynyl; C1-C12halogenoalkyl or a group NR13R14; in which R13 and R14 independently of one another are hydrogen or C1-C6alkyl or together are tetra- or pentamethylene; R2 and R3 independently of one another are hydrogen; C1-C8alkyl; C1-C8alkyl which is substituted by hydroxyl, C1-C4alkoxy, mercapto or C1-C4alkylthio; C3-C8alkenyl; C3-C8alkynyl; C3-C8cycloalkyl or C3-C8cycloalkyl-C1-C4alkyl, or in which the two groups R2 and R3, together with the carbon atom to which they are bonded, form a three- to eight-membered carbocyclic ring; R4 is hydrogen or C1-C6alkyl; R5 is hydrogen; C1-C6alkyl or phenyl, which is unsubstituted or can be substituted by halogen, nitro, C1-C4alkyl, C1-C4halogenoalkyl, C1-C4alkoxy or C1-C4alkylthio; and R6 is a group G  one another are hydrogen or C1-C6alkyl; p is the number zero or one; and R9, R10 and R11 independently of one another are hydrogen, C1-C6alkyl, C1-C6halogenoalkyl, C3-C6alkenyl, C3-C6alkynyl, C1-C6alkoxy, C3-C6alkenyloxy, C3-C6alkynyloxy, C1-C6alkylthio, halogen or nitro are valuable microbicides. They can be employed in crop protection in the form of suitable compositions, for example for controlling fungal diseases.
Patent EP-0763032-A1 (EP)
Inventor: CHEN CHENG Y
IPC: A61P9/00
Filed: 1995-05-19
Abstract: A new process is described for the synthesis of the triazolyl tryptamine:   <IMAGE>   and related compounds. The process involves a palladium-catalyzed ring closure between a substituted ortho-iodoaniline and a protected 1-alkynol. The process is carded out at high temperature, e.g. 100 DEG  C., in a dry inert solvent, e.g., DMF and in the presence of a proton acceptor, e.g., Na2CO3 or a trialkylamine. The triazolyl tryptamine, as well as acid addition salts thereof, is a 5 HT1D receptor agonist having anti-migraine properties.
Patent EP-0760615-A1 (EP)
Inventor: ARMSTRONG JEFFREY A
IPC: A47C9/10
Filed: 1995-05-22
Abstract: A collapsible sunshade (50) includes a pair of support arms (54a, 54b). Disposed on outer ends of the support arms are a pair of ribs (62a, 62b). A fabric sheet (51) is disposed between the ribs to form a sunshade. The support arms include a pair of outwardly extending lever arms (58a, 58b). The ribs similarly include a pair of lever arms (64a and 64b). A pair of push rods (70a, 70b) extend between the lever arms of the support arms and the ribs. As the support arms are moved from a closed position in which they are substantially parallel to an open position in which they are substantially apart, the lever arms cause the ribs to extend outwardly thereby extending the shade. Preferably the sun shade is designed to be fitted on a collapsible headrest such that the combination of the collapsible shade and headrest can be easily stowed and transported by a user.
Patent EP-0767785-A1 (EP)
Title: Method of producing 1,2-butylene oxide
Inventor: LINGELBACH PETER
IPC: C07D301/00
Filed: 1995-06-16
Abstract: PCT No. PCT/EP95/02337 Sec. 371 Date Dec. 27, 1996 Sec. 102(e) Date Dec. 27, 1996 PCT Filed Jun. 16, 1995 PCT Pub. No. WO96/00222 PCT Pub. Date Jan. 4, 1996A process for the preparation of 1,2-butylene oxide by the catalytic hydrogenation of vinyl oxirane, in which use is made of a palladium catalyst on a support of barium sulfate, zirconium oxide or titanium dioxide or a rhenium-containing supported palladium catalyst.
Patent EP-0768989-A1 (EP)
Inventor: PERANDER MICHAEL
IPC: C03C13/06
Filed: 1995-06-13
Abstract: Compositions de verre destinées à la fabrication de laine minérale présentant des caractéristiques physiologiques favorables ainsi que des caractéristiques techniques et économiques favorables sur le plan de la production et des produits. Cette composition de verre contient du SiO2 à raison de 45 à 55 % en poids, du Al2O3 à raison de 0 à 8 % en poids, du B2O3 à raison de 0,3 à 5 % en poids, des oxydes de Fe à raison de 0 à 10 % en poids, des oxydes alcalino-terreux à raison de 32 à 45 % en poids, et des oxydes alcalins à raison de 0 à 6 % en poids. On a également prévu des associations favorables de différents oxydes.
Patent EP-0719221-A1 (EP)
Inventor: EPPICH ALFRED
IPC: C04B41/45
Filed: 1995-06-27
Abstract: Die Erfindung betrifft ein Verfahren zur Herstellung keramischer Abziehbilder im Offsetdruck, bei dem auf ein Trägerpapier zunächst ein aus vorgeschmolzenem Glas (Flußmittel) und Firnis bestehender Vordruck und anschließend ein oder mehrere Farbdrucke aufgebracht werden, wobei als Druckfarbe ein Gemisch aus Farbkörpern und Firnis verwendet wird. Ihr liegt die Aufgabe zugrunde, dieses bekannte Verfahren zu vereinfachen und eine bessere Bildqualität zu ermöglichen. Das wird erfindungsgemäß dadurch erreicht, daß unter Weglassung des Vordrucks der erste Farbdruck unmittelbar auf das Trägerpapier aufgebracht wird, wobei als Druckfarbe eine Anpastung aus Farbkörper, hochbenetzendem Firnis und fein aufgemahlenem Flußmittel oder fein aufgemahlener keramischer Farbe verwendet wird.
Patent EP-0775351-A1 (EP)
Inventor: SALA OSCAR GOTLIEB
IPC: G09G3/20
Filed: 1995-08-11
Abstract: PCT No. PCT/AU95/00491 Sec. 371 Date Feb. 11, 1997 Sec. 102(e) Date Feb. 11, 1997 PCT Filed Aug. 11, 1995 PCT Pub. No. WO96/05587 PCT Pub. Date Feb. 22, 1996An improved display system which is able to display both static and moving graphics on a reduced number of pixels. The display system relies upon the beta apparent movement effect to "fill in" the blank spaces between active pixels to give the appearance of supporting an image which does not in fact exist. The display system can display moving graphics at high resolution and static graphics at low resolution.
Patent EP-0792142-A1 (EP)
Title: Constituants de stabilisation de structures a deux couches et leur utilisation dans la formation de liposomes fusiogenes programmables
Inventor: HOLLAND JOHN W
IPC: A61K47/18
Filed: 1995-10-02
Abstract: La présente invention se rapporte à un liposome fusiogène comprenant un lipide qui peut se présenter sous la forme d'une phase non lamellaire, mais peut cependant adopter une structure à deux couches en présence d'un constituant de stabilisation de structures à deux couches. L'invention concerne également un tel constituant de stabilisation de structure à deux couches, associé de manière réversible au lipide afin de stabiliser ce dernier lorsqu'il adopte une structure à deux couches. De tels liposomes fusiogènes sont extrêmement avantageux dans la mesure où non seulement il est possible de prédéterminer la vitesse à laquelle ils deviennent fusiogènes, mais également de la faire varier selon les besoins sur une plage de temps allant de quelques minutes à plusieurs jours. La régulation de la fusion liposomique s'effectue par modulation de la stabilité chimique et/ou de l'aptitude à l'échange du ou des constituants de stabilisation. Les liposomes fusiogènes selon la présente invention peuvent être utilisés pour l'apport de médicaments, de peptides, de protéines, d'ARN, d'ADN et d'autres molécules bioactives à des cellules cibles concernées.
Patent EP-0790839-A1 (EP)
Inventor: REZAI EBRAHIM
IPC: A61L15/24
Filed: 1995-10-30
Abstract: Porous, absorbent macrostructures that comprise flexible interparticle bonded aggregates and are useful in absorbent articles such as diapers, adult incontinence pads, and sanitary napkins are disclosed. These porous macrostructures are treated with an effective amount of a latex to coat at least a portion of the particles comprising the bonded aggregate so as to impart increased flexibility to the macrostructure. This latex is capable of being sintered at a temperature of about 25  DEG C or lower, is at least somewhat hydrophilic when sintered, and has a Tg of about 25  DEG C or lower when sintered.
Patent EP-0800433-A1 (EP)
Inventor: ALTPETER ARNO
IPC: B23K20/10
Filed: 1995-11-29
Abstract: Die Erfindung betrifft ein Verfahren zum Prüfen von durch Ultraschalldrahtbonden hergestellten Verbindungen, bei welchem die Festigkeit der Verbindung als maßgebende Größe für die Bondgüte ermittelt wird. Es wird vorgeschlagen, daß als für die Festigkeit der Verbindung maßgebende Parameter die Geschwindigkeit bzw. der zeitliche Verlauf der Drahtdeformation und der zeitliche Verlauf der Bondkeilamplitude während des Bondvorgangs erfaßt und durch Vergleich mit in einem Prozeßsicherungsbaustein gespeicherten, einem vorgegebenen Qualitätsstandard entsprechenden Daten bewertet werden. Dadurch ist es möglich, daß jede einzelne Verbindung ohne zusätzlichen Zeitaufwand störungsfrei auf Festigkeit geprüft werden kann.
Patent EP-0790843-A1 (EP)
Title: Appareil de verrouillage destine a la liberation lente d'un medicament par un distributeur actionne par le patient
Inventor: RUBSAMEN REID M
IPC: A61M5/14
Filed: 1995-10-27
Abstract: La présente invention concerne un procédé permettant de contrôler l'accès à un médicament, dans un appareil de libération de médicaments sous la forme d'aérosols, grâce à un dispositif de verrouillage et à une clef électroniques. On limite l'accès à l'utilisateur prévu en remettant à celui-ci une clef à codage unique, lisible par la machine, qui correspond au code unique du dispositif de verrouillage. La mise en contact du dispositif de verrouillage et de la clef correspondants donne à un moyen de contrôle un signal autorisant l'utilisation de l'appareil. Plus particulièrement, le procédé est appliqué à une méthode de contrôle de la douleur constituée par l'apport intrapulmonaire d'une préparation analgésique active sur le plan pharmaceutique. La préparation est fournie automatiquement par un appareil (1) indépendant portable, tenu à la main, qui comporte un moyen de libération automatique d'une quantité dosée de médicament dans le flux inspiratoire (11) d'un patient en réaction à des informations reçues d'un moyen (21) servant à mesurer et à déterminer séparément le débit inspiratoire et le volume inspiratoire d'un patient.
Patent EP-0793699-A1 (EP)
Title: Heterospiro-compounds and their use as electroluminescent materials
Inventor: KREUDER WILLI
IPC: H05B33/14
Filed: 1995-11-22
Abstract: The invention concerns the use in electroluminescent devices of heterospiro-compounds of formula (I), in which Γ means an element of the fourth main group of the periodic system of elements, with the exception of carbon, and is preferably Sn, Ge or Si, particularly preferably Ge or Si, and K?1 and K2¿, independently of each other, mean conjugated systems. The compounds of formula (I) are distinguished by good solubility in common organic solvents, improved film-forming properties and a considerably reduced tendency towards crystallization.
Patent EP-0752996-A1 (EP)
Inventor: ARNOLD MICHAEL
IPC: C07F7/30
Filed: 1995-12-22
Abstract: L'invention porte sur un procédé de synthèse permettant d'obtenir un sesquioxyde de germanium carboxyéthyle pur en l'absence d'impuretés toxiques. Dans le cadre de ce procédé, ni le dioxyde de germanium ni le germanium métallique ne constituent des produits de départ. Le procédé comporte plusieurs étapes, soit: a) s'assurer de l'absence de tout tétrachlorure de germanium résiduel afin d'éviter qu'il ne contribue à la formation d'oxyde de germanium, b) éliminer tout dioxyde de germanium, c) faire disparaître toute trace de tétrachlorure de germanium qui aurait été produit, dans l'intervalle, par un quelconque dioxyde de germanium et, d) éliminer définitivement toute trace de dioxyde de germanium. Selon un autre procédé, on obtient un produit intermédiaire, de l'acide propionique trichlorogermane, (TPA), par la précipitation directe d'une solution concentrée au moyen d'un solvant halogéné, du dichlorométhane, de préférence, versé dans un solvant non polaire alkyle, de préférence de l'hexane, à la température ambiante, produit intermédiaire que l'on convertit ensuite en sesquioxyde de germanium carboxyéthyle.
Patent EP-0728778-A1 (EP)
Inventor: HORI NAOMI
IPC: C08F236/22
Filed: 1996-01-09
Abstract: A film-forming resin comprising a copolymer consisting of: (a) from 30 to 80 % by weight of a (meth)acrylamide monomer represented by the formula (1) wherein R 1  represents CH 3 , etc. and R 2  and R 3  represent each a hydrogen atom or a C 4  - C 12  alkyl group; (b) from 2 to 50 % by weight of a (meth)acrylamide monomer represented by the formula (2) wherein R 4  and R 5  represent each a hydrogen atom or a C 1  - C 3  alkyl group; (c) from 0 to 30 % by weight of a (meth)acrylate monomer or a (meth)acrylamide monomer represented by the formula (3) wherein R 6  represents a C 2  - C 3  alkyl group, R 7  and R 8  represents each CH 3  or C 2 H 5 , and a represents a number of 0 or 1; and (d) from 0 to 40 % by weight of a (meth)acrylate monomer represented by the formula (4) wherein R 9  and R 10  represent each a C 2  - C 4  alkylene group, R 11  represents a hydrogen atom, CH 3  or C 6 H 5 , and b and c represent each a number of from 0 to 50; and a hair care product containing the same:
     
       
     The film-forming resin of the present invention makes it possible to sustain a hair style over a prolonged period of time even under a high humidity. Further, it is excellent in shampoo-washability. When used as a hair-styling resin, it achieves an effect of giving a long-lasting and good finishing.
Patent EP-0722194-A1 (EP)
Inventor: MORI TOSHIYUKI
IPC: H01M8/12
Filed: 1996-01-09
Abstract: A defective fluorite structure type solid electrolyte of the following formula (1):  
 
        {(M 1-a A a ) x Ce 1-x }O 2-y      (1) 
 
wherein M is a trivalent rare earth element other than Ce, A is a monovalent alkali metal or a bivalent alkaline earth metal, and a, x and y are 0<a<0.6, 0.2<x<0.5 and 0<y<0.55, respectively.
Patent EP-0738676-A1 (EP)
Inventor: EGLI ERNST
IPC: B28C5/02
Filed: 1996-02-03
Abstract: The spraying device has an annular insertion component in the supply line. An inlet channel (10) comes out into an annular chamber (7) in this component. There are several outlet channels (9) from the annular chamber to the supply flow. The inlet channel is tangential, so that the annular chamber becomes a turbulence or circulation chamber. The outlet channels are spaced uniformly round the annular chamber and lead to the internal boring (8) of the insertion component. The input apertures of the dividing channels are close to the bottom of the annular chamber. These channels are angled inwards and come out in the internal boring of the insertion part.