baber/WOPTO huggingface dataset:
Patent SI-1146892-T1 (SI)
Title: Baff, inhibitors thereof and their use in the modulation of the b-cell response
Inventor: BROWNING JEFFREY
IPC: A61K39/00
Filed: 2000-01-25
Abstract: Stimulating B-cell growth, immunoglobulin production, or dendritic cell-induced B-cell growth and maturation, or co-stimulating B-cell growth and immunoglobulin production, comprising administering a composition containing the tumor necrosis factor family B cell activating factor (BAFF) or its active fragment, and optionally an anti-Micro antibody, a CD40 ligand or an anti-CD40 ligand, is new. An independent claim is also included for a method of inhibiting B-cell growth, immunoglobulin production, or dendritic cell-induced B-cell growth, or co-inhibiting B-cell growth and immunoglobulin production, comprising administering an anti-BAFF ligand molecule, a recombinant, inoperative BAFF ligand molecule, an antibody specific for BAFF ligand, active fragments of the molecules, or an antibody specific for BAFF ligand receptor, or an epitope of it. ACTIVITY : Immunosuppressive; virucide; antiinflammatory; hypotensive; nephrotropic; cardiant; cytostatic. No biological data is given. MECHANISM OF ACTION : B-cell growth and/or immunoglobulin production stimulators or inhibitors.
Patent SI-1458360-T1 (SI)
Title: Pulmonary delivery of aminoglycosides
Inventor: TARARA THOMAS E
IPC: A61K9/00
Filed: 2002-12-19
Abstract: The present invention is directed to the administration of aminoglycosides. In particular, the present invention is directed to compositions and methods for the pulmonary administration of aminoglycosides. According to a preferred embodiment, compositions and methods are provided for the localized treatment of respiratory infections.
Patent SI-2186664-T1 (SI)
Title: Method and an apparatus to cut out a vehicle glazing panel
Inventor: FINCK WILLIAM
IPC: B62D65/08
Filed: 2005-09-14
Abstract: A winder unit (1) is disclosed for use with a cutting wire in cutting out a vehicle glazing panel. The unit is capable of being mounted to the glazing panel and includes first and second winder spools (4,5) for winding cutting wire. At least one wire wrap around guide element (typically a pulley) is positioned away from the mounting means wherein 
i) the wire is secured to a single spool only of the unit and, with the wire connected to the single connected spool only, a cut is effected with the unit in a first mounted position; and the unit is moved to a second mounted position with the wire remaining connected to the single connected spool only, prior to further cutting; and/or 
ii) one or both spools are provided with a respective ratchet mechanism, the ratchet mechanism being released during the procedure such that the wire becomes slackened. 
The unit (1) may be used in various techniques either alone or with an auxiliary guide arrangement (2).
Patent SI-1760383-T1 (SI)
Title: Corner piece system for connecting flanges of sheet metal canal sections
Inventor: PRECHTL HANS-PETER
IPC: F16L23/00
Filed: 2006-09-01
Abstract: Corner angle system comprises a first side element (16) having a flared flange (34) which is formed with a locking nub (42) facing an insertion section (20) and a second side element (18) lying on a longitudinal edge with a locking recess (46). The nub fits the recess when the side elements are joined. Preferred Features: The side elements have the same wall thickness and the bevels of the side elements have different depths so that the sum of the depths equals the wall thickness of the side elements.
Patent SI-1856965-T1 (SI)
Title: Reversible plough with overload safety device
Inventor: MEURS WILHELM
IPC: A01B61/00
Filed: 2006-05-19
Abstract: The reversible plow has an overload safety system comprising a hydraulic cylinder (9) mounted between the T-shaped plow-beam (2) and a console (6) connecting it to the machine frame (7). Diagonal supporting strips (15, 16) are pivoted on the console, their opposite ends being connected to the cylinder.
Patent SI-2348016-T1 (SI)
Title: Phenyl pyrrole aminoguanidine derivatives
Inventor: BOMAN ARNE
IPC: C07D207/00
Filed: 2007-06-11
Abstract: The present invention relates to phenyl pyrrole aminoguanidine derivatives of the general formula (I):   
including tautomeric forms thereof, wherein n is 1, 2 or 3; or a pharmaceutically acceptable salt thereof. The present invention further relates to the use of such phenyl pyrrole aminoguanidine derivatives for the treatment of diseases associated with the melanocortin receptors or related systems, e.g. the melanocyte stimulating hormones.
Patent SI-2285350-T1 (SI)
Title: Methods for the preparation of targeting agent functionalized diblock copolymers for use in fabrication of therapeutic nanoparticles
Inventor: ALI MIR M
IPC: A61P35/00
Filed: 2009-06-16
Abstract: This application provides nanoparticles and methods of making nanoparticles using pre-functionalized poly(ethylene glycol)(also referred to as PEG) as a macroinitiator for the synthesis of diblock copolymers. Ring opening polymerization yields the desired poly(ester)-poly(ethylene glycol)-targeting agent polymer that is used to impart targeting capability to therapeutic nanoparticles. This "polymerization from" approach typically employs precursors of the targeting agent wherein the reactivity of functional groups of the targeting agent is masked using protecting groups. Also described is a "coupling to" that utilized the poly(ethylene glycol)-targeting agent conjugate where the targeting agent remains in its native un-protected form. This method uses "orthogonal" chemistry that exhibit no cross reactivity towards functional groups typically found within targeting agents of interest.
Patent DE-3586361-T2 (DE)
Inventor: BRIGGS JONATHAN
IPC: G01N21/64
Filed: 1985-03-13
Granted: 1993-03-11
Abstract: A beam of incident electromagnetic radiation is generated having a spatial distribution of intensity periodically varying in time. A receiver suspected of containing an analyte is irradiated with the beam, and the electromagnetic signal emitted is detected and the correlation, if any, is determined between the periodicity of the applied beam and fluctuations in the detected signal. The method and apparatus have particular applicability in the field of particle detection, e.g. fluorescent particle detection.
Patent DE-3786304-T2 (DE)
Inventor: JACOBS MARTIN J
IPC: A61K31/335
Filed: 1987-07-03
Granted: 1993-10-21
Abstract: The Resorcyclic Acid Lactone (RAL) derivatives zearalenone, zearalanone, zearalene, zearalane, zearalenol, zearalanol, dideoxyzearalane and pharmaceutically acceptable salts thereof can be administered to vertebrates to non-specifically stimulate the immune system.
Patent DE-3788904-T2 (DE)
Inventor: MALOBERTI RENE
IPC: F16L37/00
Filed: 1987-07-10
Granted: 1994-08-04
Abstract: Connecting device for quick release under load, in particular for pipes transporting fluids such as hydrocarbons, characterised in that it comprises, between two facing structural elements (1, 2), or between two parts of a member connecting the two structural elements, at least one linking device comprising an internally profiled annular collar (7) consisting of at least two segments of complementary shape, a rod (4) provided with an outer profile corresponding to the inner profile of the collar and engaged inside the said collar and extending over at least part of the height thereof, and an annular sleeve (6) engaged on the said nut and capable of being displaced axially with respect thereto under the effect of an actuating member such as an actuator (12) acting directly or indirectly on the said sleeve. 
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Patent DE-3872435-T2 (DE)
Inventor: KENT ALEXANDER GEORGE
IPC: C07C11/107
Filed: 1988-04-21
Granted: 1992-12-03
Abstract: 2.3-Dimethylbutene-1 (2,3-DMB1) is produced from propene by a process comprising the steps of:   (A) converting propene in one or more stages to a product comprising 2,3-dimethylbutene-2 (2,3-DMB-2) under conditions whereby the proportion of 2,3-DMB-2 in the product is maximised,   (B) separating 2,3-DMB-2 from the product of step (A), and (C) contacting the 2,3-DMB-2 separated in step (B) with a catalyst active for the isomerisation of 2,3-DMB-2 to 2,3-DMB-1 under conditions whereby 2,3-DMB-2 is isomerised to 2,3-DMB-1. e
Patent DE-3872489-T2 (DE)
Inventor: MAITLAND ALEXANDER DR
IPC: C22C21/00
Filed: 1988-10-13
Granted: 1993-03-11
Abstract: The present invention relates to an aluminum alloy containing vanadium characterized by improved corrosion resistance and articles made therefrom wherein said articles when anodized have a uniformly grey, light-fast surface and a reflectivity of at most 50%.
Patent DE-3885188-T2 (DE)
Inventor: VAN DE GRIFT ROBERT EMILE JOHAN
IPC: H03M1/36
Filed: 1988-07-21
Granted: 1994-05-05
Abstract: The circuit comprises a first and a second pair of inputs (2, 2 min ; 3, 3 min ) and at least three pairs of outputs (20, 20 min ; 24, 24 min ; 21, 21 min ). The pairs of inputs serve to receive pairs of two input signals (V1, V1c, V5, V5c) which are substantially complementary to one another. At least two pairs of outputs (20, 20 min ; 24 , 24 min ) serve to supply pairs of two substantially complementary output signals. A first output (21) of the third pair of outputs (21, 21 min ) is coupled to a first input (2) of the first pair of inputs (2, 2 min ). The second output (21 min ) of the third pair of inputs is connected to a circuit node which is not one of the inputs of the first pair of inputs. This node is for example the first input (3 min ) of the second pair of inputs (Figure 9). Another possibility is to couple node to one end (38) of the impedance element (32) which has its other end coupled to the second input (2 min ) of the first pair of inputs.
Patent TR-199800974-T2 (TR)
Inventor: ESSWEIN ANGELIKA
IPC: A61P19/10
Filed: 1996-11-26
Abstract: Formül I bilesikleri        Formül (1)         ki burada R1 hidrojen ya da metildir, R2 1-10 karbon atomuna sahip düz zincirli ya da dallanmis bir asagi alkildir, R3 hidrojen ya da asagi alkildir, n 0-12 arasindadir, R4 6-24 karbon atomuna sahip alkil, alkenil ya da alkinildir, bunlarin üretimi için islemler ve osteoporozun tedavisi için bu bilesikleri içeren farmasötik ajanlar.
Patent TR-199801143-T2 (TR)
Inventor: FINCH CHARLES W
IPC: A01N37/36
Filed: 1996-12-17
Abstract: Burada temin edilen, ortalama çaplari 1 mikrondan büyük olan, polivinil alkol ("PVA") partikülleri içinde disperse edilmis bir bitki, büyüme regülatör formülasyonudur. Mevcut bulus, ortalama çapi 1 mikrondan daha büyük olan, PVA'ün sulu bir dispersiyonunu içeren bir emülsiyonu da içerir. Yukaridaki formülasyonlar, bir bitkideki bitki büyüme faktörünü gelistirme konusundaki yöntemlerde kullanislidir
Patent TR-199801443-T2 (TR)
Inventor: THUNE MARIE-PIERRE DE B
IPC: G01N33/50
Filed: 1997-01-24
Abstract: A method for managing HIV chemotherapy of HIV positive patients comprises: (a) transfecting an HIV infection-susceptible cell line with an HIV pol gene sequence obtained from a patient and a HIV-DNA construct from which the sequence has been deleted; (b) culturing the transfected cells so as to create a stock of chimeric viruses; (c) assessing the phenotypic sensitivity of the chimeric viruses to an inhibitor of the HIV pol gene-encoded enzyme and assigning a value; (d) constructing a data set comprising the value for chimeric virus sensitivity and the corresponding value for a chimeric wild-type strain of HIV; (e) repeating the sensitivity assessment for at least two further inhibitors and thereby constructing at least three such data sets; (f) representing the data sets in 2-D or 3-D graphical form such that the difference between the chimeric and wild-type sensitivities in each data set provides a visual measure of the resistance of the chimeric stock to treatment by the inhibitor; and (g) selecting the optimum inhibitor(s) on the basis of the graphical representation of the resistances.
Patent TR-199801616-T2 (TR)
Inventor: WANG YICHUN
IPC: C09D9/00
Filed: 1997-02-21
Abstract: Bir mürekkep/silme akiskan kombinasyonu, bir boyayi ve bir baglama maddesini ihtiva eden bir mürekkep ve bir bazik azot bilesigini ihtiva eden bir silme akiskanini kapsamaktadir. Baglama maddesi bazik azot bilesigine baglanabilmektedir.
Patent TR-199901260-T2 (TR)
Inventor: MARTI ERWIN
IPC: C07C259/06
Filed: 1997-12-08
Abstract: Sindirim kanali disinda uygulanabilen  yagin içinde süspanse edilmis en az 8 karbon atomuna sahip olan bir alifatik sülfinik asitin desferrioksamin-B tuzunun parçaciklarindan olusan, sindirim kanali disinda enjekte edilebilir bir kompozisyon. Desferrioksamin B dekansülfonik tuzunun yeni kristal modifikasyonlari saglanmistir ve göze çarpan kararliliktaki bir kristal formu açiklanmistir.
Patent TR-199903319-T2 (TR)
Inventor: MOREAU ANDR
IPC: F23N5/10
Filed: 1998-06-30
Abstract: The invention concerns a tap comprising a rod (6) adjusting the gas flow rate arranged inside a bore (18) of the tap body (4), comprising a cavity (80) communicating axially with a first gas passage (30), and laterally with an orifice 838) formed through the bore side wall, at the end of a second gas passage (36). The area of coincidence between the orifice (38) and a lateral opening (84) of the rod varies continuously and gradually during the rotation of the rod inside the bore. A thrust bearing (14) axially adjustable by means of a certain compressibility of its fixing tab (108) enables to calibrate the tap while it is being manufactured. The invention is applicable to taps for gas appliances.
Patent DE-60001104-T2 (DE)
Inventor: BATTAGLIA GIANPAOLO
IPC: A41D15/00
Filed: 2000-02-07
Granted: 2003-11-27
Abstract: The invention realizes a connecting band between garments covering the upper and lower part of the body, that will close on itself and be secured to a garment or a part of it. A bearing number of protruding tabs (2) can be attached in a removable way to at least one of said garments or part of it by means of pressure fastenings present in the tabs.
Patent DE-60003589-T2 (DE)
Inventor: ALTAMURA PAOLO
IPC: B62M11/04
Filed: 2000-02-11
Granted: 2004-07-01
Abstract: A pin (14) for connecting a gear (5) to a supporting member (6) has a first (19) and a second (20) longitudinal end portion connectable to the supporting member (6); a first intermediate portion (21) extending from the first end portion (19); and a second intermediate portion (22) extending from the second end portion (20), and which differs in size from the first intermediate portion (21) and has a flexural strength differing from that of the first intermediate portion (21). <IMAGE>
Patent DE-60005222-T2 (DE)
Inventor: WILLEBRAND HEINZ
IPC: H04B10/118
Filed: 2000-12-26
Granted: 2004-07-01
Abstract: A hybrid wireless optical and radio frequency (RF) communication link utilizes parallel free-space optical and RF paths for transmitting data and control and status information. The optical link provides the primary path for the data, and the RF link provides a concurrent or backup path for the network data, as well as a reliable and primary path for the control and status information. When atmospheric conditions degrade the optical link to the point at which optical data transmission fails, the hybrid communication link switches to the RF link to maintain availability of data communications. The switch may occur automatically, based on an assessment of the quality of the optical signal communicated through the optical path. <IMAGE>
Patent DE-60006205-T2 (DE)
Inventor: BIHR ERIC
IPC: G09F11/29
Filed: 2000-04-26
Granted: 2004-04-15
Abstract: Device for posting bills by unwinding a fabric (300) carrying information, in which the fabric (300) is wound and unwound around two motorized and synchronized rollers (100, 200) in such a way that the fabric (300) is kept under tension as it is unwound, characterized in that:the top end (310) of the fabric (300) is mounted removably on a fixing module (110) secured to the upper roller (100);the fixing module (110) is connected to the upper roller (100) by an unwinding mechanism (400) allowing the fixing module (110) to be moved down close to the lower roller for fitting and removing the top end (310) of the fabric (300);it comprises means (500, 501, 340) for keeping the fabric under transverse tension.
Patent DE-60008340-T2 (DE)
Inventor: KREBS ROBERT R
IPC: B32B15/08
Filed: 2000-11-20
Granted: 2004-12-02
Abstract: A magnetically active laminate is disclosed. The magnetically active laminate is composed of a resin impregnated layer bonded to a distinct, magnetically active sheet. The laminate is especially well suited for use in the construction of erasable markerboards and cubicle panels, although many applications are possible within the scope of the present invention. <IMAGE>
Patent DE-60016035-T2 (DE)
Inventor: CARR ANTHONY HUGH
IPC: C12Q1/02
Filed: 2000-12-15
Granted: 2005-11-10
Abstract: The invention relates to microbiological test processes, in particular those involving testing of the influence of antimicrobial compounds, nutrients and vitamins or other growth promoters. In particular the invention relates to the typical growth response of a majority of microbes constituting a main population group from a typical growth response of a minority of microbes constituting a minor sub-population group.
Patent DE-60020119-T2 (DE)
Inventor: HAEMAELAEINEN MAIKKU
IPC: G01N33/94
Filed: 2000-06-19
Granted: 2005-10-06
Abstract: A method and apparatus for assaying a drug candidate with a biosensor having one or more sensing surface-bound biomolecules associated therewith are disclosed. The method comprises the steps of measuring the binding interaction between the drug candidate and the one or more sensing surface-bound biomolecules of the biosensor to obtain an estimate of at least one binding interaction parameter of the drug candidate, and then comparing the estimated binding interaction parameter against a mathematical expression correlated from binding interaction data associated with known drug compounds to determine an estimate of at least pharmacokinetic parameter of absorption, distribution, metabolism, or excretion (ADME) that is related to the drug candidate. The present invention allows for the simultaneous measurement of different pharmacokinetic parameters of the drug candidate, as well as an indication of the drug candidate's solubility, by use of a single analytical instrument. The pharmacokinetic data may be represented as a ADME characterization profile; such ADME profiles are of great utility for purposes of drug screening and lead optimization.
Patent DE-60023654-T2 (DE)
Inventor: TELL PETER
IPC: B01D46/24
Filed: 2000-01-21
Granted: 2006-07-20
Abstract: Ejector type vacuum pump, comprising a rotationally symmetric ejector body (4) arranged in a house to be contained in a vacuum chamber (3) that extends axially and opens through a wall of the house, a dust filter (15) running concentrically about the eject body comprising a tube shaped, porous filter body, a frame circumferentially enclosing the filter body so that the filter body and frame form a self containing unit that extends substantially about the whole length of the ejector body to be axially fixed by a muffler (11) that is received in the opening of the vacuum chamber.
Patent DE-60027007-T2 (DE)
Inventor: LANGEREIS SANDER
IPC: C01B33/38
Filed: 2000-07-03
Granted: 2006-10-26
Abstract: A process for production of a polyolefin-based composite material of high rigidity, containing a polyolefin and a layered clay, involves impregnating a layered, swellable clay which is interstratified with a tetraalkyl cation, with at least one polymerizable monomer and then mixing this impregnated clay with a polyolefin and a peroxide, at a temperature above the melting point of the polyolefin. A polyolefin-based composite material containing 98-50 wt. % of a polyolefin, 1-50 wt. % of another homo- or copolymer and 1-50 wt. % of a layered clay, wherein the ratio between the modulus of elasticity of the material and that of the initial polyolefin, at a temperature which is 30° C. below the melting temperature of the polyolefin, is higher than or equal to 1 has high rigidity.
Patent DE-60037528-T2 (DE)
Inventor: CHANG KENT KUOHUA
IPC: H01L27/115
Filed: 2000-07-14
Granted: 2008-12-24
Abstract: The present invention provides a method and a NAND-type flash memory device. The method includes forming a select gate oxide layer in a select transistor area of a substrate and a tunnel oxide layer in a memory cell area of the substrate; forming a doped amorphous silicon layer on the select gate oxide layer and the tunnel oxide layer, the doped amorphous silicon layer having a dopant level which simultaneously avoids a select transistor word line high resistance problem and a charge gain/charge loss problem; forming an insulating layer on the doped amorphous silicon layer; forming a control gate layer on the insulating layer; and etching at least the doped amorphous silicon layer, the insulating layer, and the control gate layer to form at least one memory cell stack structure and at least one select transistor stack structure. In a preferred embodiment, the polysilicon layer which forms both the floating gate of the flash memory cell and the select gate of the select transistor of the device is doped with between approximately 5x1018 and 8x1019 ions/cm3 of phosphorus. With this dopant level, the contact resistance of the select transistor's control gate is low, thus keeping the word line resistivity of the device low. Simultaneously, contamination of the tunnel oxide of the flash memory cell by the dopant is limited, allowing for the interface between the floating gate and the tunnel oxide to be smooth, which prevents charge gain/loss problems. Thus, the reliability of the device is increased.
Patent DE-60100573-T2 (DE)
Inventor: GRESSIER CHRISTOPHE
IPC: B65D90/10
Filed: 2001-02-12
Granted: 2004-06-24
Abstract: The tanker vehicle tank has a cylindrical casing (1) closed at each end and having an access hatch (2) at the top. The hatch has a cylindrical shaft (21) and a cover (22). The shaft extends into the tank from the top (11) at a level such that the upper surface of the cover defines a plane (A) parallel to and at a small distance from the top. The shaft is enclosed by a flank (24) opening at a point on the tank.
Patent DE-60105062-T2 (DE)
Inventor: ANDRE JEAN-LUC
IPC: B61D47/00
Filed: 2001-12-21
Granted: 2005-08-18
Abstract: The invention concerns a railway unit (1) consisting of two end running assemblies (5) and (6) interconnected by a pivoting support railway structure (10) detachable to take up an oblique loading and unloading position. The invention is characterised in that the pivoting support railway structure (10) comprises at least at one of its ends (5) and (6) lockable support and bearing means (16) mobile between two positions, said means (16) being designed to lock the rear axle wheels of the second tractor (4) transported with a first tractor (3) in the place of a semi-trailer on the same railway unit and bring it into a lifted transporting position. The invention is of interest to manufacturers of railway equipment for combined rail/road transport.
Patent DE-60106002-T2 (DE)
Inventor: SALARI HASSAN
IPC: C07K14/52
Filed: 2001-04-12
Granted: 2006-02-02
Abstract: In accordance with various aspects of the invention, CXCR4 agonists, including SDF-1 polypeptides and SDF-1 polypeptide homologues, may be used in reducing the rate of hematopoietic cell multiplication. Methods of the invention may comprise administration of an effective amount of an CXCR4 agonist to cells selected from the group consisting of hematopoietic stem cells and hematopoietic progenitor cells. Cells may be treated in vitro or in vivo in a patient. A therapeutically effective amount of the CXCR4 agonist may be administered to a patient in need of such treatment. Patients in need of such treatments may include, for example patients requiring bone marrow or peripheral blood stem cell transplantation.