baber/WOPTO huggingface dataset:
Patent CA-2128164-A1 (CA)
Title: Process for the preparation of high purity buspiron and the hydrochloride thereof
Inventor: MEZEI TIBOR
IPC: A61K31/505
Filed: 1994-07-15
Abstract: A b s t r a c t The invention relates to a process for the preparation of    8-[4-[4-(pyrimidine-2-yl)-piperazine-1-yl]-butyl]--8-aza-spiro[4,5]decane-7,9-dione (buspiron) of the Formula I                            (I) and  the  hydrochlorides  thereof  having  high  purity by subjecting 8-[4-[4-(pyrimidine-2-yl)-piperazine-1-yl]--but-2-inyl]-8-aza-spiro[4,5]decane-7,9-dione of the Formula II                       (II) to catalytic hydrogenation in the presence of a palladium or Raney-nickel  catalyst  in  an  inert  organic solvent and optionally converting the 8-[4-[4-(pyrimidine-2-yl)--piperazine-1-yl]-butyl]-8-aza-spiro[4.5]decane-7,9-dione thus  obtained  into  the  hydrochloride  thereof  which comprises  continuously  adding  a  solution  8-[4-[4--(pyrimidine-2-yl)-piperazine-1-yl]-but-2-inyl]-8-aza--spiro[4.5]decane-7,9-dione formed with an inert organic solvent  having  a  concentration  of  at  least  40  %  by weight to a suspension of a catalyst in an inert organic solvent, removing the catalyst and subsequently a) isolating the 8-[4-[4-(pyrimidine-2-yl)-piperazine--1-yl]-butyl]-8-aza-spiro[4.5]decane-7,9-dione base and/or b) treating the 8-[4-[-(pyrimidine-2-yl)-piperazine-1--yl]-butyl]-8-aza-spiro[4.5]decane-7,9-dione  base with hydrogen chloride in ethanol or isopropanol under stirring at a temperature between 15 °C and 40 °C and isolating the 8-[4-[4-(pyrimidine-2-yl)--piperazine-1-yl]-butyl]-8-aza-spiro [4.5]decane-7,9--dione hydrochloride melting at 188-191 °C, or c) treating the 8-[4-[4-(pyrimidine-2-yl)-piperazine-1--yl]-butyl]-8-aza-spiro[4.5]decane-7,9-dione base with hydrogen chloride in ethyl acetate or isopro-panol at a temperature not exceeding 70°C under stirring and isolating the 8-[4-[4-(pyrimidine-2-yl)--piperazine-1-yl]-butyl]-8-aza-spiro [4.5]decane-7,9--dione hydrochloride melting at 201-203 °C.
Patent CA-2129624-A1 (CA)
Title: Liposomal piroxicam formulations
Inventor: LUCCHETTI GIOVANNI
IPC: A61K9/127
Filed: 1993-02-04
Abstract: The present invention relates to a topical liposomal formulation comprising piroxicam, a phospholipid, a solvent system for piroxicam and said phospholipid, water and conventional auxiliary formulating agents, and a method of preparing said formulation.
Patent CA-2129671-A1 (CA)
Title: Method for treatment of potato pulp
Inventor: OLSEN HANS S
IPC: A23K30/18
Filed: 1993-01-28
Abstract: In the method for treatment of potato pulp the potato pulp is first cooked and subsequently, after proper cooling, exposed to an enzymatic degradation process by means of a cell wall degradation enzyme, and then, if necessary, preserved to a product, which exhibits microbial stability. Hereby a cheap and simple conversion of the potato pulp to a nutritionally valuable and stable fodder is achieved.
Patent CA-2130008-A1 (CA)
Inventor: PLESH RONALD L SR
IPC: B21B43/04
Filed: 1993-04-06
Abstract: A method for cooling hot metal plates (20) formed in a plate mill and inserts therefor. The metal plates are slid over a cool-ing bed plate transfer grid (10) having a plurality of inserts (40, 110, 200 or 300) supporting rollers (42, 128, 210 or 310) wherein the metal plates are in contact with the rollers for decreased friction and reduced marring of the metal plates. The insert is clamped to the transfer grid so that it is easily and quickly removable and replaceable for cost effective plate cooling.
Patent CA-2130012-A1 (CA)
Title: Method and system for broadcast and group communications in a communications system
Inventor: BENDLE IAN N
IPC: H04W4/08
Filed: 1994-08-12
Abstract: A Method and System for Broadcast and Group Communications in a Communications System Abstract of the Disclosure A communications system is provided comprising at least one base station (18, 19, 20, 21) and a plurality of remote units (22-26). Each remote unit has an identification. The remote units are arrangeable into at least one group and are arranged to communicate with the base station over a radio link. A group service centre (GSC 12) is provided comprising means for receiving trafficfrom an inbound channel from the radio link and copying it into an outbound channel to the radio link. At least one remote unit has means for communicating its identification to the GSC and establishing a communication link with the GSC. In a first aspect the GSC comprises look-up means (102) for correlating theidentification of the remote unit with identifications of other remote units in a common group and means for individually establishing communication links with said other remote units using the identifications of those remote units. In a second aspect remote unit control information is periodically transmitted (208) to each remote unit in the group while the group is established and upon input of atransmission requirement (257) to a remote unit the remote unit transmits on thereserved traffic channel with transmissions adjusted according to the remote unit control information.
Patent CA-2130773-A1 (CA)
Title: Closure Device for Controlling a Door Lock, in Particular the Door Lock of an Oven
Inventor: SAUVAGNAT RENE
IPC: F24C15/02
Filed: 1994-08-24
Abstract: The invention relates to a closure device for controlling a door lock, in particular the door lock of an oven, comprising a U-shaped grip (6) mounted on the locking side (11) of the door opposing the hinges of the door and rotatable about a vertical axis (9) relative to the door, the grip having a vertical grip arm (7) arranged at a distance from the rotational axis (9) of the grip (6), a magnet (22) being provided at the lower side of the grip arm, and a magnetic switch (18) fixed in the oven frame and connected electrically via a direct or indirect circuitry with the control members of the locking mechanism.   When the door is closed, the magnet (22) and the magnetic switch (18) are opposite one another.
Patent CA-2131232-A1 (CA)
Title: Pvc-based gas generant for hybrid gas generators
Inventor: TAYLOR ROBERT D
IPC: C06D5/06
Filed: 1994-08-31
Abstract: IMPROVED PVC-BASED GAS GENERANT FOR HYBRID GAS GENERATORS ABSTRACT OF THE DISCLOSURE The amount of particulate matter that is forced into the passenger compartment of an automobile by the deployment of an air bag as it protects the lives of occupants is reduced by improving the filterability of the combustion products of a composition for generating gas to inflate the bag. The filterability is improved by adding a nucleating agent for alkali metal halide vapors formed during said combustion. Silica, alumina, and graphite are representative of the nucleating agents.
Patent CA-2134065-A1 (CA)
Title: Grease compositions
Inventor: WIGGINS GARY W
IPC: C10N10/06
Filed: 1994-10-21
Abstract: Improved grease compositions comprise a major amount of an oil based metal soap thickened base gease selected from the goup consisting of complex and failed complex greases, at least one sulfur and phosphorus containing composition alone or together with an overbased metal salt of an organic acid and a hydrocarbyl phosphite, in amounts sufficient to increase the dropping point of the base grease, as measured by ASTM Procedure D-2265 by at least 15°C, the phosphorus and sulfur compound being described in detail herein.
Patent CA-2134211-A1 (CA)
Inventor: WOODWARD JAMES K
IPC: A61K31/445
Filed: 1993-04-06
Abstract: L'invention a trait à un procédé permettant de susciter un effet antihistaminique nécessaire à un patient souffrant de troubles hépatiques. Elle consiste à lui administrer en quantité efficace sur le plan antihistaminique un composé de formule (I), où R1 représente hydrogène ou hydroxy; R2 représente hydrogène; ou bien R1 et R2 conjointement forment une deuxième liaison entre les atomes de carbone qui les portent; n est un nombre entier allant de 1 à 5; R3 représente -COOH ou -COOalkyle où la fraction alkyle comporte 1 à 6 atomes de carbone sous forme droite ou ramifiée; A et B représentent chacun hydrogène ou hydroxy à condition que l'un au moins représente hydrogène. On décrit en outre un sel de ce dérivé qui est pharmaceutiquement acceptable et des isomères individuels de ce sel.
Patent CA-2139995-A1 (CA)
Title: Needle sorting device
Inventor: DEMAREST DAVID
IPC: A61B17/06
Filed: 1995-01-11
Abstract: A needle sorting device comprises an infeed device which singulates and randomly deposits surgical needles upon a first conveyor for transmission to a processing station.  Upon transit, one or more cameras to obtain an image of the deposited needles. The image is digitized and the digital signals are transmitted to a control system computer which evaluates the position and orientation for randomly positioned needles and processes the information to obtain data for communication to one or more robot assemblies having grippers.  Utilizing the position and orientation data, the robot assembly grippers removes selected needles from the first conveyor and transfers each needle to an engagement device located upon a second precision conveyor.  This second precision conveyor is provided with additional devices to further orient the needle transferred thereto.  Each oriented needle is conveyed by the second conveyor to an automatic swaging station where sutures are automatically attached.
Patent CA-2142239-A1 (CA)
Title: Spring retainers for hose couplings
Inventor: PRUZIN MICHAEL J
IPC: F16L37/12
Filed: 1995-02-10
Abstract: An end coupling for a brake hose is retained in an opening through a chassis bracket by a spring assembly comprised of a wave spring and an anchor spring.  The wave spring engages a first surface of the bracket with portions of an undulating surface while the anchor spring engages a second surface of the bracket with a plurality of flared tangs.
Patent CA-2143646-A1 (CA)
Title: Low profile gastrostomy device with dome
Inventor: GOLDHARDT DONALD JAY
IPC: A61J15/00
Filed: 1994-04-12
Abstract: A gastrostomy device (30) for easier insertion into an established stoma is provided with an apertured dome (34) connected at its bottom wall to a tubular shaft (31), wherein the dome is particularly characterized by having the sidewall (38) thinned from apex to bottom wall whereby the dome, when elongated with an obturator, stretches smoothly and readily to very close to the diameter of the tubular shaft. The device is ordinarily provided with a one-way valve (42) mounted in the dome as well as with a retention flange (32) at the outer end of the tubular shaft. Preferably the one-way valve is a cross-slit duckbill valve of novel design.
Patent CA-2144041-A1 (CA)
Title: Rockbolt
Inventor: NES ODDBJOERN
IPC: E21D20/00
Filed: 1993-08-24
Abstract: Device for fastening of a rockbolt (12) in a hole (11) in rock, provided with an expansion bushing (14) at the inner end. At the outer end of the rockbolt, a washer like pressure member (18) is arranged to press against the rock (19), with a nut (16). The rockbolt (12) is provided with a tube (23) extending over at least the greater part of its free length, and is provided to supply cementing grout to the inner end of the rock hole and expelling of air from the rock hole. The tube is preferably connected to transfer cementing grout through the annular passage created in the tube.
Patent CA-2146064-A1 (CA)
Title: Nonwoven fabric from blends of isotactic and atactic polyolefins
Inventor: MCMANUS JEFFREY LAWRENCE
IPC: D04H1/42
Filed: 1995-03-31
Abstract: There is provided a nonwoven fabric comprising a layer of  a  nonwoven  web  comprising  filaments  prepared  from  a thermoplastic polymer.  The thermoplastic polymer is a blend of at least one isotactic polymer having an isotacticity of at least 85, up to 40 weight percent of at least one atactic polymer having an isotacticity of less than 20, and the blend may also have a fluorocarbon in an amount between about 0.1 and 3.0  weight percent.   The  fabric may be  produced by the spunbonding and meltblowing processes and has good strength, barrier and softness.
Patent CA-2146343-A1 (CA)
Title: Liquid spray masking composition
Inventor: LAPPI LARRY R
IPC: B05D1/32
Filed: 1993-07-21
Abstract: An improved liquid spray masking composition including an effective amount of a non-volatile polyhydroxy component is provided. The preferred polyhydroxy components comprise polyglycerols, especially triglycerols or larger polyglycerols. The presence of such materials in masking compositions improves performance of the compositions with respect to inhibition of high temperature swelling, blistering or spotting of the painted surface to which it is applied.
Patent CA-2151247-A1 (CA)
Title: Side sealing arrangement for sieve devices
Inventor: AHORNER LEANDER
IPC: B07B1/46
Filed: 1994-10-07
Abstract: The invention relates to a side sealing arrangement for sieve devices which has a grate comprising a plurality of grate rods (3, 4) which are alternately movable and immovable with respect to the side walls (2) and which are connected by flexible sieve components (6) which are secured to the grate rods, bridge the gaps between the latter and can be moved, that is tensioned and released, by the movable grate rods, the side sealing arrangement (8) which is made of flexible material being rigidly connected firstly to the sieve components (6) and secondly to side frame parts and comprising sealing sheets (8) which overlap one another in an imbricated manner. In order to increase the useful life of the sealing sheets and to improve the sealing properties, the invention proposes that, viewed in the sieving direction, each sealing sheet (8) extends between two grate rods (3) which are stationary relative to the side wall (2).
Patent CA-2156429-A1 (CA)
Inventor: WAKE DAVID
IPC: H04B10/2575
Filed: 1994-02-16
Abstract: A transducer (1) for use in a hybrid op-tical and radio communications system com-prises a zero electrical power photodetector (2), and a radio antenna (3). The photodetector (2) is directly electrically connected to the radio antenna (3) so that in use optical signals are received and radio signals are transmitted by the transducer (1) without the use of electrical power. The transducer (1) can thus be remotely sited at locations in communication systems not having a supply of electrical power. In a first embodiment the photodetector comprises a zero-bias photodiode, and in a second embodi-ment the transducer (1) comprises a self-biasing photodetector.
Patent CA-2160956-A1 (CA)
Title: Melt-processed blends containing poly(vinyl alcohol)
Inventor: BRADY JEAN MARIE
IPC: C08L29/04
Filed: 1995-10-19
Abstract: Polymers containing a high percentage of vinyl alcohol units are difficult to process into sheet, film, injection-molded objects, or fibers. Such melt-processing is greatly enhanced by admixing certain core/shell copolymers having either a rubbery, crosslinked core mainly of units derived from butadiene and/or an alkyl acrylate, or a non-cross-linked core derived mainly of units derived from an alkyl acrylate, and an outer  shell mainly of units derived from methyl methacrylate.  Such copolymers do not require the presence of functional groups capable of reaction with the hydroxyl groups of the poly(vinyl alcohol).
Patent CA-2162849-A1 (CA)
Title: Universal Spacer for Concrete Reinforcement Rods
Inventor: GAVIN NORMAN W
IPC: E04C5/20
Filed: 1994-04-28
Abstract: A single unit, stiff and strong plastic molded wheel spacer (20) for a reinforcement rod (30) used in con-crete is split into two sections (34, 36) connected by an integral hinge (26) at one end and fastened together by a ratchet assembly (84) at the other end. The rod is gripped at the cen-ter of the wheel by a pair of saddles (42, 44), one on each section. A fin-ger (76) attached to one of the sections between the saddle and hinge prevents the rod from moving past the saddle to the hinge.
Patent CA-2165291-A1 (CA)
Title: Pourable canola oil for food applications
Inventor: COVINGTON ROBERT MELVIN JR
IPC: C11C3/12
Filed: 1994-06-10
Abstract: A pourable partially hydrogenated canola oil having a maximum saturated fatty acid content of about 9.6 % and a maximum trans fatty acid content of about 22.1 % especially suitable for food applications is disclosed.
Patent CA-2166275-A1 (CA)
Inventor: GOSSELINK EUGENE PAUL
IPC: C11D3/37
Filed: 1994-02-10
Abstract: Anionic sulfonated poly-ethoxy/propoxy, especially modified isethionate, end-capped esters useful as soil release agents in detergent compositions are presented. The terephthalate esters are homogeneously integrated with one or more crystallization-reducing stabilizers.
Patent CA-2168013-A1 (CA)
Title: Alkaline ammoniacal cupric chloride etching bath containing a copper (i) stabilizer
Inventor: RICHARDSON HUGH WAYNE
IPC: H05K3/06
Filed: 1994-09-08
Abstract: Copper etchant solution additives (18) for use with an aqueous alkaline ammoniacal cupric chloride etching bath (12) include several compounds, each of which is shown to stabilize the copper (I) state. The compounds discovered by tbe present invention include iodide ions such as potassium iodide, ammonium iodide, sodium iodide, calcium iodide and magnesium iodide. Other copper (I) stabilizers discovered by the present invention include certain water soluble salts containing sulfur such as a thiocyanate ion (e.g. ammonium thiocyanate, potassium thiocyanate, sodium thiocyanate, magnesium thiocyanate, and calcium thiocyanate) and a thiosulfate ion (e.g. ammonium thiosulfate, potassium thiosulfate, sodium thiosulfate, magnesium thiosulfate, and calcium thiosulfate). Etching rates for alkaline ammoniacal cupric chloride with different concentrations of potassium iodide, ammonium thiocyanate, and sodium thiosulfate were studied. The results of controlled experiments revealed that adding concentrations up to approximately 1200 mg/L of any one of these compounds to the alkaline ammoniacal cupric chloride etchant resulted in a 20-130 % increase in etch rate.
Patent CA-2171117-A1 (CA)
Title: A mechanical triturator for biological material
Inventor: ROGGERO GIANMARCO
IPC: G01N33/48
Filed: 1994-09-26
Abstract: A mechanical triturator for biological mate-rial comprises a cylindrical housing (2) defining a chamber (4) in which a cutting member (6) con-stituted by a perforated plate is disposed.  A rotor member (16), mounted for rotation in the chamber (4), has a screw (20) which cooperates with the cut-ting member (6) in order, as a result of its rotation, to supply the biological material into contact with the cutting member (6) and to cause the trituration thereof.
Patent CA-2175269-A1 (CA)
Inventor: MESHER TERRY
IPC: F25C1/14
Filed: 1996-04-29
Abstract: A fluidized particle production system includes a solidifying unit having a forming surface for supporting a solidified layer of a medium, e.g. ice and a treatment apparatus for removing the solidified medium from the solidifying surface and sizing the removed solidified medium into particles of desired dimensions. The treatment apparatus comprising a sizing device co-operating and moving with the solidifying surface for effecting therebetween the sizing of the particles. A housing encloses the solidifying unit and the treatment apparatus and a sweep fluid outlet is positioned to discharge sweep fluid towards the sizing device for fluidizing the particles and transporting the fluidized particles through an outlet duct from the housing.
Patent CA-2179649-A1 (CA)
Title: Use of pla2 inhibitors as treatment for alzheimer's disease
Inventor: CLEMENS JAMES ALLEN
IPC: A61P25/28
Filed: 1994-12-14
Abstract: This invention provides methods for the treatment or prevention of Alzheimer's disease in a mammal which comprises administering to a mammal in need thereof an effective amount of an inhibitor of phospholipase A2. This invention also provides a series of compounds which are useful as inhibitors of phospholipases A2, especially cytosolic phospholipase A2.
Patent CA-2180348-A1 (CA)
Inventor: PLOURDE ROBERT JR
IPC: A61K47/48
Filed: 1995-01-11
Abstract: Cette invention concerne des conjugués utilisés pour cibler un agent thérapeutique sur une cellule comprenant des récepteurs d'asialoglycoprotéine. Ces conjugués comprennent un agent thérapeutique et un ligand destiné au récepteur d'asialoglycoprotéine, ledit agent thérapeutique et ledit ligand étant liés par un agent de pontage. L'agent de pontage peut être un agent de réticulation, une molécule porteuse polyfonctionnelle ou un agent de réticulation et une molécule porteuse polyfonctionnelle. Dans une forme de réalisation préférée l'agent thérapeutique est un analogue nucléosidique ou de la colchicine et le ligand est de l'asialoorosomucoïde, de l'arabinogalactane ou un tri-(N-acétyle galactosamine aminohexyle glycoside) amide de tyrosyl(glutamyl)-glutamate. Les agents de réticulation préférés comprennent les dérivés d'aminoacyle, les dérivés de carboxyacyle, le phosphate, les peptides et les agents de réticulation labiles par réduction. Les molécules porteuses polyfonctionnelles comprennent les acides polyamino et les polysaccharides. On peut utiliser les conjugués de cette invention pour cibler un agent thérapeutique sur une cellule, par exemple pour inhiber la réplication d'ADN viral dans un hépatocyte infecté par un virus.
Patent CA-2180762-A1 (CA)
Title: Potable germicide to kill helicobacter pylori bacteria
Inventor: NELSON PETER VICTOR
IPC: A61K31/045
Filed: 1996-07-09
Abstract: It has recently been discovered that gastritis is caused by an infection of the stomach by a germ, namely Helicobacter Pylori.  This infection can, over time, lead to ulcers and cancer.  Physicians can cure the infection with a combination of up to four patented antibiotics, albeit with risk of side effects and at substantial expense.  It is estimated by medical authorities that 50% of the world population has the problem.  An appropriately concentrated solution of ethanol ingested under the right conditions can also cure the infection at minimal cost and without burden to clinical resources.
Patent CA-2181889-A1 (CA)
Title: Polyaspartic acid having more than 50 % beta form and less than 50 % alpha form
Inventor: KOSKAN LARRY P
IPC: C02F5/12
Filed: 1995-01-26
Abstract: .beta.-Polyaspartic acid having a weight average molecular weight of 1000 to 5000 produced by hydrolysis of anhydropolyaspartic acid exhibits a high degree of calcium carbonate and calcium phosphate inhibition.
Patent CA-2182892-A1 (CA)
Title: Container side
Inventor: KARPISEK LADISLAV STEPHAN
IPC: B65D6/16
Filed: 1995-12-13
Abstract: A container side having an upper part (6) and a lower part (7) hinged together by a hinge (19) so the upper part can pivot relative to the lower part.To substantially eliminate pressure loads on the hinge as are exerted by the load within the container of which the side is an element, load resisting means (12, 15) are provided to couple adjacent sides of the upper and lower parts. In a hinging sequence of the upper part (6) relative to the lower part (7) from a loading condition where the parts (6, 7) are overlying to an operational condition where they are coplanar, the load resisting means (12, 15) will automatically engage when the side parts (6, 7) approach the operational condition and will automatically disengage when the upper part (6) is hinged from the coplanar operational condition.
Patent CA-2184839-A1 (CA)
Inventor: POOLE JAMES EDWARD
IPC: C09D5/02
Filed: 1995-03-08
Abstract: Des compositions de revêtement aqueuses comprennent des résines formant un film polymère et environ 0,1 à 5 % en poids de la base pondérale des solides résineux d'un oligomère contenant d'environ 2 à 4 fractions d'uréthane, d'urée ou d'amide par molécule, et deux ou plusieurs fractions selectionnées dans le groupe composé d'hydroxyle et d'amine tertiaire. L'oligomère améliore le poli du revêtement obtenu.