baber/WOPTO huggingface dataset:
Patent KR-20100114091-A (KR)
Title: Apparatus, and associated method, for selecting speech coder operational rates
Inventor: FURBECK DAVID
IPC: H04W88/02
Filed: 2009-02-19
Abstract: An apparatus and an associated method for facilitating selection of CODEC availability from amongst a set of CODECs at a communication device. A battery power measurer measures the stored energy level of a battery power supply that powers a communication device of which the CODEC forms a portion. A selector selects the available CODECs responsive to the measured power level. If the measured level is less than a threshold, then high-sampling-rate CODECs are at least selectably made unavailable for use. If the battery level is higher than the threshold, then the high-sampling-rate CODECs are made available for use. If the level is greater than a threshold then both a high sampling-rate and the low sampling-rate CODEC are available. An indication generator generates an indication of selection made by the selector.
Patent KR-20100112198-A (KR)
Title: Wheel for hydraulic machine and hydraulic machine including such a wheel
Inventor: MAZZOUJI FARID
IPC: F03B3/12
Filed: 2009-02-13
Abstract: The invention relates to a wheel (R) of the Francis type that comprises a ring (1) with revolution symmetry about the rotation axis (Z) of the wheel (R), and curved blades (21, 22) connected to the ring (1) and each having an outer peripheral edge (212, 222) and an inner central edge (211, 221). The connection points (B21, B22) between the ring (1) and the inner central edges (211, 221) of the blades (21, 22) are located on a same circle (C20) centered on the axis (Z). The connection points (A21, A22) between the ring (1) and the outer peripheral edges (212, 222) of the blades (21, 22) are located on at least two distinct circles (C21, C22) (D21, D22) centered on the axis (Z).
Patent KR-20100139011-A (KR)
Title: Liquid-crystalline medium
Inventor: WITTEK MICHAEL
IPC: C09K19/42
Filed: 2009-02-19
Abstract: The invention relates to a liquid-crystalline medium comprising one or more compounds of the formula I in which R0, ring A and L1-4 have the meanings indicated in Claim 1, and to the use thereof in electro-optical liquid-crystal displays.
Patent KR-20100127851-A (KR)
Inventor: MANDYAM GIRIDHAR D
IPC: H04W4/00
Filed: 2009-03-20
Abstract: 위젯 콘텐츠 전달을 위한 전송 최적화를 위한 장치 및 방법들은 복수의 정보 계층적 깊이(depth)들을 가지는 모바일 위젯에 대응하는 업데이트된 콘텐츠를 획득하는 단계, 및 상기 모바일 위젯에 대응하는 사용자 네비게이션 패턴 이력(historical) 데이터를 획득하는 단계를 포함할 수 있으며, 상기 사용자 네비게이션 패턴 이력 데이터는 상기 복수의 정보 계층적 깊이들에 대응한다.  양상들은 또한 디바이스로의 전달을 위해 제 1 콘텐츠 업데이트 메시지에 포함하기 위해 제 1 정보 계층적 깊이 레인지를 획득하는 단계를 포함할 수 있으며, 여기서, 상기 제 1 정보 계층적 깊이 레인지는 상기 사용자 네비게이션 패턴 이력 데이터에 기반한다.  또한, 양상들 상기 제 1 정보 계층적 깊이 레인지에 대응하는 상기 업데이트된 콘텐츠의 제 1 부분을 이용하여 상기 제 1 콘텐츠 업데이트 메시지를 생성하는 단계를 포함한다.  선택적으로, 양상들은, 제 1 콘텐츠 업데이트 메시지에서 업데이트된 콘텐츠의 제 1 부분의 크기를 감소함으로써 업데이트된 콘텐츠의 제 1 압축된 부분을 정의하는 단계를 더 포함한다.
Patent KR-20110003504-A (KR)
Inventor: NELSON JAMES M
IPC: C08K9/04
Filed: 2009-03-26
Abstract: 충전 수지의 제조 방법은 작용화된 입자를 제공하는 단계; 및 진공 혼련기(vacuum kneader) 내에서, 작용화된 입자를 유기 매트릭스와 조합하고 균질하게 혼합하여, 작용화된 입자가 충전 수지의 적어도 약 20 중량%를 차지하도록 충전 수지를 제공하는 단계를 포함한다.  작용화된 입자를 제공하는 단계는 또한 (i) 미처리된 입자, (ii) 상기 입자와 반응하는 표면 처리제, 및 (iii) 용매의 공급 재료를 제공하는 단계와; 상기 입자를 표면 처리제와 반응시키기에 충분한 온도로 유지된 연속 반응기를 통해 공급 재료를 안내하여 약 4시간 이내에 작용화된 입자를 제공하는 단계와; 작용화된 입자를 연속 반응기로부터 직접 진공 혼련기 내로 안내하는 단계를 포함할 수 있다.  다른 태양에서, 최종 수지(finished resin)는 유기 매트릭스 내에 적어도 약 20 중량%의 작용화된 입자를 포함한다.
Patent KR-20100128354-A (KR)
Title: Method and apparatus for variable accuracy inter-picture timing specification for digital video encoding
Inventor: HASKELL BARIN G
IPC: H04N19/94
Filed: 2003-07-11
Abstract: A method and apparatus for variable accuracy inter-picture timing specification for digital video encoding is disclosed. Specifically the present invention discloses a system that allows the relative timing of nearby video pictures to be encoded in a very efficient manner. In one embodiment, the display time difference between a current video picture (105) and a nearby video picture is determined. The display time difference is then encoded (180) into a digital representation of the video picture. In a preferred embodiment, the nearby video picture is the most recently transmitted stored picture. For coding efficiency, the display time difference may be encoded using a variable length coding system or arithmetic coding. In an alternate embodiment, the display time difference is encoded as a power of two to reduce the number of bits transmitted.
Patent KR-20120084846-A (KR)
Title: Air conditioning network system and control method of air conditioning apparatus
Inventor: MOON MU HYUN
IPC: F24F11/02
Filed: 2011-01-21
Abstract: PURPOSE: An air conditioning network system and a method for controlling an air conditioner are provided for users to easily use the air conditioner by simply selecting a desirable indoor unit using a portable terminal. CONSTITUTION: An air conditioning network system comprises a portable terminal(20), indoor units(10), a serve(40), line sharers(1,2), and a communications module. The portable terminal is formed to download a program. The indoor unit is remotely connected to the portable terminal to communicate. The serve controls a plurality of the indoor units. The line sharers wireless-communicates with at least one among the indoor units or the portable terminal. The communications module is mounted to the indoor units and the portable terminal. The communications module comprises a Wifi-module.
Patent KR-20120087710-A (KR)
Title: Latency control circuit and control method of the same
Inventor: KIM KYUNG HOON
IPC: G11C8/00
Filed: 2011-01-28
Abstract: PURPOSE: A latency control circuit and a controlling method thereof are provided to accurately control data output latency by compensating the variation of delay time of a data output path. CONSTITUTION: A delay locked loop(100) generates a delay locked clock signal by delaying a clock signal corresponding to delay time changed according to a dual locking point and generates a loop change signal by changing a locking point. A control unit(130) generates a latency control signal in response to a reset signal, a delay signal, and a loop change signal. A latency signal generating unit(140) controls a latency of a command signal in response to a latency control signal to be outputted as a latency signal.
Patent KR-20120088101-A (KR)
Title: Security apparatus of cassette
Inventor: YUN SU HYOUN
IPC: G07F19/00
Filed: 2011-01-31
Abstract: PURPOSE: A cassette security system is provided to improve the security thereof by realizing solenoid type security. CONSTITUTION: A solenoid(200) is fixed to a lateral frame(100). The solenoid is turned on. An actuating rod descends. The solenoid is turned off. The actuating rod rises. A locker(250) is connected to the actuating rod. The locker goes in gear with a slave gear and performs a lock function. An operator(300) is installed in the lateral frame to be slid. The operator is elastically operated in order to push the inner side of a cassette door. A hanging device is fixed to the operator. The hanging device moves the locker in the operation of the operator.
Patent KR-20120090298-A (KR)
Title: Apparatus and method for scheduling task and resizing cache memory of embedded multicore processor
Inventor: CHUNG SUNG WOO
IPC: G06F9/46
Filed: 2011-02-07
Abstract: PURPOSE: A task scheduling/cache memory resizing device of an embedded multi core processor and a method thereof are provided to reduce energy/power consumption by periodically decentralizing a task to cores. CONSTITUTION: A task number recognizing unit(32) recognizes the number of non-periodic tasks. A comparing unit(34) compares the number of the non-periodic tasks with a critical value. A core controlling unit(36) controls the number of cores(10-16) for periodic task. The comparing unit includes a timer for calculating the number of non-periodic tasks.
Patent KR-20120090661-A (KR)
Title: Golf training apparatus
Inventor: CHOI HYUN MEE
IPC: A63B69/36
Filed: 2011-02-08
Abstract: PURPOSE: A golf training apparatus is provided to allow users at remote places to play golf games and to provide accurate golf training services to the users. CONSTITUTION: A golf training apparatus includes a posture information collecting part, a communicating part(14), and a displaying part(13). The posture information collecting part collects posture information with respect to the swing posture of a user. The communicating part transfers the collected information to a web server(30). The communicating part receives golf training service information or golf game service information. The golf training service information includes the analysis result of the posture information. The displaying part displays the received information.
Patent KR-20120091634-A (KR)
Title: Anion generator nozzle of anion generator having the function of wind vane with no driving power
Inventor: KANG CHANG HWAN
IPC: A61L9/22
Filed: 2011-02-09
Abstract: PURPOSE: An anion generator nozzle of an anion generator having a non-power driven wind vane is provided to quickly purify indoor air by releasing anion from a discharge electrode of a lead wire without using a fan motor. CONSTITUTION: An anion generator module provides a voltage for generating anion. A lead wire(200) is connected to the anion generator module, formed with a discharge electrode(210) on the leading end thereof, and located in the center of a cover(100). An annular metal plate(300) is located on the inner side of the cover close to the lead wire. The distance between the discharge electrode of the lead wire and the metal plate is properly changed in consideration of the size of the cover or the size of an anion generator.
Patent KR-20120092466-A (KR)
Title: Paper-based nanogenerator
Inventor: KIM SANG WOO
IPC: H01L41/02
Filed: 2011-02-11
Abstract: PURPOSE: A paper based nano power generating device is provided to easily grow a ZnO nano rod with a piezoelectric property on paper. CONSTITUTION: A bottom substrate(10) is made of paper. A bottom electrode(20) is formed on the bottom substrate. A piezoelectric material layer(30) is formed on the upper side of the bottom electrode. A top electrode(40) is formed on the upper side of the piezoelectric material layer. A top substrate(50) is formed on the top electrode.
Patent KR-20120092805-A (KR)
Inventor: JOUNG JAE YOUL
IPC: E01C5/22
Filed: 2011-02-14
Abstract: 본 발명은 보도블록에 관한 것으로, 합성목재로 이루어지며 일면이 개구된 외부덮개; 상기 외부덮개의 내부에 충진되는 내부충진물; 및 상기 내부충진물 내부에 위치하여 내부충진물에 크랙이 발생하는 것을 방지하는 크랙방지부재;를 포함하는 것을 특징으로 한다. 본 발명은 상기 구성에 의해서, 합성목재로 이루어진 외부덮개로 인해 외관이 수려한 미감을 주면서 동시에 내부에는 무기질소재의 내부충진물로 충진됨으로써 충분한 강도를 발휘하는 효과가 있고, 내부충진물에 크랙이 발생하는 것을 방지하는 크랙방지부재를 구비함으로써, 내부충진물이 갈라지는 등의 손상이 발생하는 것을 방지하는 유리한 효과가 발생한다.
Patent KR-20120094634-A (KR)
Title: Method for evaluating wafer
Inventor: LEE WOO SUNG
IPC: H01L21/66
Filed: 2011-02-17
Abstract: PURPOSE: A method for evaluating a wafer is provided to efficiently determine a determination area by a selective defect like an edge ring or center disk when a defective map is determined. CONSTITUTION: A surface of a wafer is thermally processed(S110). The thermally processed surface of the wafer is etched(S120). A part of the wafer is polished(S140). A defect of an O band region of the wafer is detected with a TZDB(Time Zero Dielectric Breakdown) method. An oxide layer is formed on the surface of the wafer(S150).
Patent KR-20120096332-A (KR)
Title: Embedded semiconductor device including phase change random access memory element storing intrinsic chip data and method of fabricating the same
Inventor: YU TEA KWANG
IPC: H01L21/8247
Filed: 2011-02-22
Abstract: PURPOSE: An embedded semiconductor device having a phase change random access memory element and a manufacturing method thereof are provided to prevent intrinsic chip data being lost during testing a thermal stability because a memory layer of a sub-memory element is formed with materials having thermal stability more excellent than a memory layer of a main memory element. CONSTITUTION: Semiconductor chips having a main memory element and sub-memory element are integrated on a substrate(S1). An intrinsic chip data is prepared by electrically testing the conductive chips(S21). The intrinsic chip data is recorded in a sub-memory element(S22). Thermal stability test of the each semiconductor chip are performed(S23). The semiconductor chips are packaged(S3).
Patent KR-20120097057-A (KR)
Inventor: BYUN CHANG SUNG
IPC: E06B3/96
Filed: 2011-02-24
Abstract: 본 발명은 복층유리용 스페이서 마감부재에 관한 것으로서, 보다 상세하게는 마감부재는 스페이서가 구비된 복층유리의 가장자리를 결속시키는 것으로 몸체를 기준으로 몸체 일측의 수평으로 연장된 한쌍의 돌출핀과 한쌍의 지지핀이 형성되고, 상기 몸체의 상측에서 수직으로 연장된 한쌍의 돌출핀과 한쌍의 지지핀이 형성되는 것으로 상기 돌출핀은 스페이서의 제습공간부에 삽입되어 고정되며, 상기 지지핀은 스페이서의 건습공간부에 삽입되어 고정하여 스페이서와의 견고한 결속력으로 안정적인 복층유리 구조물을 제공하게 되고, 상기 마감부재의 지지핀 끝단에 “┕┙”형 접착부재가 부착되어 기밀성을 유지하도록 하는 복층유리용 스페이서 마감부재에 관한 것이다.
Patent KR-20120097115-A (KR)
Inventor: KIM JUNG SOO
IPC: G06Q50/10
Filed: 2011-02-24
Abstract: 본 발명은 키워드 퍼즐 게임을 이용한 광고 방법에 관한 것으로서, 보다 상세하게는 사용자가 스마트폰 등에 다운받은 퍼즐 게임 애플리케이션을 실행하여 키워드 퍼즐 게임을 할 경우, 컨소시엄으로 구성된 다수의 광고 제공업체[소위, 스폰서]가 광고하고자 하는 광고 컨텐츠[예컨대, 자동차 이미지, 영화 광고 포스터 등] 자체를 광고 키워드가 숨겨진 다수의 광고 퍼즐 조각으로 나누어서 희미하게 페이드 아웃시키고, 사용자로 하여금 동일한 광고 키워드가 숨겨진 한 쌍의 퍼즐 조각을 순차적으로 맞춰 키워드 퍼즐 게임을 클리어하도록 구성함으로써, 상기 특정 광고 제공업체의 광고 컨텐츠가 키워드 퍼즐 게임 동안 지속적이면서도 집중적으로 사용자에게 노출되어 광고 효과를 극대화시킬 수 있고, 나아가 키워드 퍼즐 게임을 클리어한 사용자에게는 그에 대한 보상으로 쿠폰을 제공하거나 쿠폰 응모할 수 있는 기회를 제공함으로써 광고 대상자인 사용자가 오히려 보다 적극적으로 키워드 퍼즐 게임에 참여하게 하고, 결과적으로 광고 제공업체가 광고하고자 하는 광고의 광고 효율성을 극대화시킬 수 있는 키워드 퍼즐 게임을 이용한 광고 방법에 관한 것이다.
Patent KR-20120097821-A (KR)
Title: Hot dip tin plated copper wire
Inventor: KIM JEONG IK
IPC: C23C2/38
Filed: 2011-02-25
Abstract: PURPOSE: A copper wire rod plated with molten tin is provided to increase the thickness and uniformity of a tin plating layer by forming multiple layers out of solder materials having different melting points. CONSTITUTION: A copper wire rod comprises a tin plating layer(20) formed by depositing two or more kinds of tin plating materials into multiple layers. The thickness of each layer of the tin plating layer is 2 micron meters or less. Tin plating materials are successively arranged in each layer of the tin plating layer in the order of higher melting point, where the melting point difference between the layers of the tin plating layer is 20°C.
Patent KR-20120103165-A (KR)
Title: Endoscope robot for paranasal sinuses surgery
Inventor: YI BYUNG JU
IPC: A61B1/233
Filed: 2011-03-10
Abstract: PURPOSE: An endoscope robot for paranasal sinuses operation is provided to observe all portions of paranasal sinuses by refracting a portion of an endoscope unit inserted inside a human body as various angles. CONSTITUTION: A bending endoscope unit(100) is entered inside nose of a patient. An operation unit(200) transfers and rotates the bending endoscope unit. A controller(500) controls operation of the operation unit. A sensing unit(300) senses location of nostrils of the patient and paranasal sinuses. A computing unit(400) indicates the location of the nostrils of the patient and the paranasal sinuses as a coordinate and transfers it to the controller. [Reference numerals] (100) Bending endoscope unit; (200) Operation unit; (300) Sensing unit; (400) Computing unit; (500) Controller
Patent KR-20110115955-A (KR)
Inventor: AKUTSU ICHIRO
IPC: F03G7/00
Filed: 2011-03-10
Abstract: 본 발명은, 장치 내에서 낙하 및 상승을 반복하여 순환하는 복수의 구체에 관한 낙하 운동 에너지를 취출할 수 있는 구체 순환 장치에 관한 것이다.   
이 구체 순환 장치는, 축수실(a), 적어도 2개의 상방향 개폐 밸브를 통해 분리된 상승실(b1, b2, b3), 배수구(12)를 갖는 낙하실(c)을 포함하며, 높은 수위의 제1 수면이 상승실(b1)의 상단 개구에, 낮은 수위의 제2 수면이 낙하실(c)의 하단 개구에 각각 형성된다.  수위가 저하된 제1 수면은 자동 급수 장치(17)로부터 급수되어 유지된다.  삽입구(15)로부터 삽입된 복수의 구체 각각은, 낙하실(c) 내를 낙하하여 제2 수면에 돌입한다.  각 구체는, 유도되어 제1 수면을 향하여 상승실(b3∼b1) 내를 부력으로 상승한다.  제1 수면에 도달한 복수의 구체의 부력으로, 하나의 구체가 제1 수면을 넘어 낙하실(c) 내를 제2 수면을 향해 낙하한다.  구체의 낙하와 상승이 반복되어, 복수의 구체 각각이 장치 내에서 순환한다.
Patent KR-20120105135-A (KR)
Title: Molded article for container flooring and method for preparing the article
Inventor: SHIN SEUNG WOO
IPC: C08L23/00
Filed: 2011-03-15
Abstract: PURPOSE: An environmentally-friendly molded product for container flooring materials and manufacturing method thereof with high strength are provided to increase cavity rate, thereby lightening weight and reducing costs. CONSTITUTION: An environmentally-friendly molded product for container flooring materials is manufactured by extrusion processing thermal molding. The thermoplastic resin composition comprises glass long fiber having length of 7-14mm and a thermoplastic resin. 40-60 weight% of the fiber glass is contained based on the total weight of composition. The thermoplastic resin is a polyolefin resin selected from polypropylene, polyethylene, polyethylene-propylene copolymer and a mixture thereof. The diameter of the fiber glass is 10-30 microns.
Patent KR-20120105848-A (KR)
Title: Thruster for a ship and ship having the same
Inventor: CHANG HANG HYI
IPC: B63H25/42
Filed: 2011-03-16
Abstract: PURPOSE: A thruster and a ship with the same are provided to improve the longitudinal thrust of a ship because the cross-sectional area of a passage in a tunnel is controlled by a nozzle unit according to a flowing direction of fluid. CONSTITUTION: A thruster for a ship comprises a tunnel(110), a propeller(120), a pair of nozzle units(130), and a driving unit. The tunnel is formed in a lateral direction of a hull. The propeller is installed in the tunnel, and flows fluid through the tunnel to generate thrust in one side or the other side of the lateral direction. The pair of nozzle units is respectively installed in both inner sides of the tunnel. In the pair of nozzle units, the cross-sectional area of a fluid passage is tapered toward a downstream of the flowing fluid. The driving unit comprises multiple nozzle plates(132,134) arranged along the circumferential direction of the tunnel. One end of the nozzle plates is hinge-coupled to the inner wall of the tunnel.
Patent KR-20120107754-A (KR)
Title: Indigo extract with improved antimicrobial, anti-inflammatory and whitening effect and soap containing indigo extract
Inventor: JANG HONG GI
IPC: C11D13/10
Filed: 2011-03-22
Abstract: PURPOSE: A manufacturing method of indigofera tinctoria extract is provided to maximize antibiotic, anti-inflammation and anti-whitening effects by controlling extraction solvent, extracting temperature, and extracting time. CONSTITUTION: A manufacturing method of indigofera tinctoria extract comprises a step of adding ethanol to indigofera tinctoria and extracting the added mixture at 25-30 °C for 11-15 hours. The added amount of the indigofera tintoria is 80-120 parts by weight. The ethanol is 90-100% ethanol and the added amount of the ethanol is 240-360 parts by weight. A soap contains the indigofera tinctoria manufactured through the same.
Patent KR-20120109093-A (KR)
Title: Laver drying board
Inventor: KIM OK SAM
IPC: A23L17/60
Filed: 2011-03-24
Abstract: PURPOSE: A laver drying screen capable of increasing the contact area in between laver and a laver screen is provided to improve the productivity of dried laver. CONSTITUTION: A laver drying screen capable of increasing the contact area in between laver and a laver screen comprises the following: a supporter(100) forming both ends of the laver drying screen having a circular or a polygon shape; a screen element(200) with the cross section located on the inside of the supporter in an octahedral shape; a weft(300) for weaving the supporter and the screen element; an auxiliary screen element(112) with the cross section located in between the supporter and the screen element in a circular or circular tube shape; circular or polygon hollow units installed inside the screen element; and an adhering layer installed on the portion for contacting the supporter, the auxiliary screen element, and the weft.
Patent KR-20120109701-A (KR)
Title: Concent formed like block
Inventor: YANG HE JIN
IPC: H01R13/10
Filed: 2011-03-25
Abstract: PURPOSE: A block type receptacle is provided to form an insertion hole for plug insertion and to configure male and female coupling structure for coupling receptacles. CONSTITUTION: A block receptacle is formed in a cube shape. An insertion hole is formed in an upper side of the block receptacle. A plug is inserted in the insertion hole. A left side and a right side of the insertion hole are composed of female and male coupling structure. The receptacle is combined with the left side and the right side of the insertion hole.
Patent KR-20120109226-A (KR)
Title: Apparatus for separating stamp and substrate
Inventor: KIM JUN TAK
IPC: B29C59/02
Filed: 2011-03-28
Abstract: PURPOSE: A bonding separation device is provided to simply proceed without the damage or deformation of a medicinal fluid-cured layer because an adhesive strength of the medicinal fluid-cured layer between bonded surfaces of glass and a stamp is eliminated. CONSTITUTION: A bonding separation device comprises a body(2), a fluid control unit(4), a fixing unit(6), a separating unit(8), an ultrasonic oscillation unit(10). The glass(G) and a stamp(S) are bonded on each other, thereby being placed on a bath(B) of the body. The fluid control unit supplies and returns the fluid to the bath of the body. A fixing tool(V) of the fixing unit holds the glass at the side of the bath. A separating tool separates the stamp from the glass by lifting up the stamp in the state of gripping one surface of the stamp. An ultrasonic oscillator(U) of the ultrasonic oscillation unit oscillates ultrasonic waves to the fluid of the bath.
Patent KR-20110110037-A (KR)
Inventor: HONG QI
IPC: G02B6/00
Filed: 2011-03-30
Abstract: 본 발명은 점 광원을 제공하는 복수 개의 고체 상태 광원들 및 점 광원들을 광의 균일한 평면으로 재배향하고 발산하는 상기 복수 개의 고체 상태 광원들 사이에 제공되는 광 재배향 영역을 갖는 복수 개의 도광 필름들을 포함하는 LCD 디스플레이를 위한 일체형 백라이트 조사 어셈블리를 제공한다. 본 발명은 상기 고체 상태 광원들을 덮는 적어도 하나의 폴리머 확산 바아 및 광학 스페이서, 칼라 부분 및 앵커 구조체를 포함하는 스페이서 칼라 링들을 더 제공하고, 상기 스페이서 칼라 링들은 상기 확산 바아 주위에 위치된다.
Patent KR-20120116215-A (KR)
Title: Preparation method of the complex of microsphere-hydrogel contained with growth factor protein
Inventor: RYU HYUN SEUNG
IPC: A61K38/18
Filed: 2011-04-12
Abstract: PURPOSE: A manufacturing method of microsphere - hydro gel composite in which growth factor protein is dipped is provided to omit sterilization process or organic solvent use in conventional protein drug delivery formulation to resolve problems followed by the sterilization process or organic solvent. CONSTITUTION: A manufacturing method of microsphere - hydro gel composite in which growth factor protein is dipped comprises the following steps: preparing porous B-TCP microsphere; dipping the growth factor protein in the microsphere; and obtaining a composite of poloxamer hydro gel and porous B-TCP microsphere by mixing the porous B-TCP microsphere with temperature sensitive poloxamer hydro gel using 3-way connector. The sintering temperature of the porous B -TCP microsphere is 1050-1250 deg. Celsius, and the initial concentration before mixing the poloxamer hydro gel with the microsphere is 33-37 wt%. The porous B -TCP microsphere has particle size of 45-75 micro meters. The sintering temperature of the porous B -TCP microsphere is 1050 deg. Celsius, and the initial concentration is 35 wt%. The porous B -TCP microsphere and poloxamer hydro gel are mixed at the same mass. [Reference numerals] (AA) BMP-2 load porous microsphere; (BB) High concentration poloxamer hydrogel; (CC) Mixing by using 3 way connector; (DD) Microsphere-hydrogel carrier which loads the BMP-2