baber/WOPTO huggingface dataset:
Patent SI-2807183-T1 (SI)
Title: Synthetic apelin mimetics for the treatment of heart failure
Inventor: GOLOSOV ANDREI
IPC: C07K14/00
Filed: 2013-01-25
Abstract: The invention provides a synthetic polypeptide of Formula I′: or an amide, an ester or a salt thereof, wherein X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, X12 and X13 are defined herein. The polypeptides are agonist of the APJ receptor. The invention also relates to a method for manufacturing the polypeptides of the invention, and its therapeutic uses such as treatment or prevention of acute decompensated heart failure (ADHF), chronic heart failure, pulmonary hypertension, atrial fibrillation, Brugada syndrome, ventricular tachycardia, atherosclerosis, hypertension, restenosis, ischemic cardiovascular diseases, cardiomyopathy, cardiac fibrosis, arrhythmia, water retention, diabetes (including gestational diabetes), obesity, peripheral arterial disease, cerebrovascular accidents, transient ischemic attacks, traumatic brain injuries, amyotrophic lateral sclerosis, burn injuries (including sunburn) and preeclampsia. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Patent TR-201104469-T1 (TR)
Title: Kararlı nikotin sakızı.
Inventor: HITE W CRAWFORD
IPC: A61K9/68
Filed: 2009-11-24
Abstract: Mevcut buluş, sakız bileşiminin, nikotin serbest bazın oksidasyonunu destekleyen bağsız elektron çiftlerini içeren sıvıları büyük ölçüde içermediği, nikotinden ve bir sakız bazından oluşan bir kararlı sakız bileşimi ile ilgilidir. Belirli yapılanmalarda sakız bileşimi nikotin serbest bazın oksidasyonunu destekleyen bağsız elektron çiftlerini içeren herhangi bir sıvı içermemektedir.
Patent TR-201210777-T1 (TR)
Title: Deniz araçları için dalga sönümleme sistemi.
IPC: B63B39/00
Filed: 2011-10-10
Abstract: Buluş, deniz araçlarına uygulanmak üzere; bir gövde (5), gövde (5) ile en az iki hareket elemanı (3) vasıtasıyla irtibatlı ve hareketli en az bir kat (2), denge bozukluklarını algılayan, gövde (5) ve/veya kata (2) konumlu en az bir denge sensörü (1) içeren, dalga hareketi ile hareketli gövdenin (5) hareketine hareket elemanları (3) vasıtasıyla ters yönde hareket üretmek suretiyle dalga hareketini sönümleme yaparak; katın (2) yeryüzüne paralel konumda kalmasını sağlayan bir dalga sönümleme sistemi ile ilgilidir.
Patent DE-3586699-T2 (DE)
Inventor: KEUCHEL HERBERT W
IPC: D04H3/16
Filed: 1985-07-16
Granted: 1993-03-25
Abstract: A method and apparatus wherein there is provided a source (11) of fiber forming material, with said fiber forming material being pumped into a die (23) having a plurality of spinnerets about its periphery. The die (23) is rotated at a predetermined adjustable speed, whereby the liquid is expelled from the die (23) so as to form fibers (25). it is preferred that the fiber forming material be cooled as it is leaving the holes in the spinnerets during drawdown. The fibres (25) may be used to produce fabrics, fibrous tow and yarn through appropriate take-up systems. The pumping system (14) provides a pumping action whereby a volumetric quantity of liquid is forced into the rotational system independent of viscosity or the back pressure generated by the spinnerets and the manifold system of the spinning head, thus creating positive displacement feeding. Positive displacement feeding may be accomplished by the extruder alone or with an additional pump of the type generally employed for this purpose. A rotary union is provided for positive sealing purposes during the pressure feeding of the fiber forming material into the rotating die (23).
Patent DE-3789810-T2 (DE)
Inventor: MARSILI LEONARDO
IPC: C07D501/22
Filed: 1987-12-22
Granted: 1994-08-18
Abstract: The invention relates to a method for preparing crystalline cefadroxil monohydrate. According to such a method a cefadroxil solvate is slurried with isopropyl alcohol containing less 6% to 18% W/W of water at a temperature between + 45 and +55 DEG C: the crystalline cefadroxil monohydrate is isolated by filtration. Some of the cefadroxil solvates which can be used are novel: they are prepared by adding dimethylacetamide, N-methyl-2-pyrrolidone or monomethylformamide to an aqueous solution of cefadroxil at a pH between 5.5 and 6.
Patent DE-3855265-T2 (DE)
Inventor: BALLY MARCEL B
IPC: A61K9/127
Filed: 1988-03-04
Granted: 1996-12-12
Abstract: A method for encapsulation of antineoplastic agents in liposomes is provided, having preferably a high drug:lipid ratio. Liposomes may be made by a process that loads the drug by an active mechanism using a transmembrane ion gradient, preferably a transmembrane pH gradient. Using this technique, trapping efficiencies approach 100%, and liposomes may be loaded with drug immediately prior to use, eliminating stability problems related to drug retention in the liposomes. Drug:lipid ratios employed are about 3-80 fold higher than for traditional liposome preparations, and the release rate of the drug from the liposomes is reduced. An assay method to determine free antineoplastic agents in a liposome preparation is also disclosed.
Patent DE-3873633-T2 (DE)
Inventor: PIERCE SUE KAREN
IPC: B08B17/02
Filed: 1988-04-20
Granted: 1993-01-28
Abstract: A process for preventing contamination of a reagent system by a reagent delivery system. The process is suitable for performing an iron determination of a sample which prevents iron contamination of the sample from metal or iron-containing surfaces contained within the apparatus used to perform the iron assay. The process comprises pretreatment of the reagent delivery system surfaces with a silane solution and then washing the pretreated surfaces with water to remove any excess silane solution. Generally, the silane solution is an organosilane solution which can be an emulsion.
Patent DE-3874409-T2 (DE)
Inventor: WALLACE KENNETH JOHN
IPC: B67D3/02
Filed: 1988-05-06
Granted: 1993-04-01
Abstract: A liquid dispenser (1) for dispensing metered aliquots of a liquid is provided, which dispenser (1) comprises a chamber (2) having an inlet bore (7) for liquid and an outlet bore (8) for liquid, a valve (3) in the chamber (2) for controlling dispense of liquid from the dispenser (1), and valve operating means (4), said valve (3) having first and second valve stems (9,10) for reception respectively within said inlet bore (7) and within said outlet bore (8), said first valve stem (9) being provided with sealing means (16) for sealing said inlet bore (7), and first, second and third resilient sealing means (22,23,24) being provided for sealing said outlet bore, the arrangement being such that during movement of the valve (3) from a position in which it entirely seals the outlet bore (8) to a position in which liquid within the chamber (2) is free to flow through the outlet bore, (7) the inlet bore is sealed before a said flow of liquid can occur.
Patent DE-3885471-T2 (DE)
Inventor: MCALISTER STEVEN A
IPC: B04B1/02
Filed: 1988-01-08
Granted: 1994-04-14
Abstract: Prior centrifugal concentrators for concentrating precious minerals use annular ribs or baffles to trap the precious minerals. Sand or magnetite tends to pack against such ribs, reducing the effectiveness of these devices. In the present invention, the inner surface of the rotating drum (2) is free of obstacles, but forms three continuous zones, a migration zone (A), a retention zone (B) and a lip zone (C). The precious mineral is retained in the retention zone by centrifugal force and friction while the unwanted slurry flows over the retention zone and out of the drum (2).
Patent DE-3885643-T2 (DE)
Inventor: JERNBERG MARITA
IPC: A47K10/38
Filed: 1988-04-14
Granted: 1994-03-10
Abstract: A holder, e.g., for rolls of paper is configured such as to dispense a paper web from the holder via a web braking element (14, 15, 17), which may have alternative forms. This element (14, 15, 17) prevents paper from being dispensed uncontrollably from the holder as a result of inertia forces or some other circumstance. The holder is comprised preferably of two major parts, namely a back plate (1) and a casing (2), which houses the roll (4) and roll support means (8, 9). When the roll (4) is placed horizontally in the casing the roll is supported on two shafts (8). When the roll extends vertically in the casing, it is supported by a shelf (9). The shelf has formed therein an aperture (10) through which the paper web passes.
Patent DE-60000004-T2 (DE)
Inventor: CHEVALIER VERONIQUE
IPC: A61Q19/00
Filed: 2000-04-03
Granted: 2002-04-25
Abstract: Anhydrous composition for application to the skin comprises: (a) surface-stabilized polymer particles dispersed in an oil phase comprising a volatile liquid (I) and a nonvolatile liqui (II), where (II) has a  delta h solubility parameter of no more than 5 (J/cm<3>)<1/2> and the (I):(II) weight ratio is 2-25:1; and (b) coloring matter.
Patent DE-60013490-T2 (DE)
Inventor: ABASCAL RUBIO JOSE MANUEL
IPC: B02C13/06
Filed: 2000-04-28
Granted: 2005-11-17
Abstract: Centrifugal thrower-crusher device for arid matter and other materials consisting in an inertia wheel (1) associated to revolvable operating means, which is foreseen of perpendicular mallets (2) diametrally matched in at least one of the faces, including the mentioned inertia wheel (1) inside a housing (3) which presents a front opening (8) at the side in which the mallets (2) are housed in a peripheral channel (17), while in the periphery another opening is defined (9), through which the materials leave, thrown in centrifugal projection, being the mentioned opening (9) directional to direct the throwing selectively. <IMAGE>
Patent DE-60013675-T2 (DE)
Inventor: LENANDER ANDERS
IPC: B23B27/14
Filed: 2000-03-29
Granted: 2005-02-10
Abstract: The present invention relates to a cutting tool insert for machining of steel comprising a cemented carbide body and a coating. The cemented carbide body comprises WC, 5-12 wt-% Co and 3-11 wt-% of cubic carbides of metals Ta, Ti and W. The amount of Nb is below 0.1 wt-% and the ratio Ta/Ti is 1,0-4,0. The Co-binder phase is highly alloyed with W with a CW-ratio of 0,75-0,95 and, finally, the cemented carbide body has a binder phase enriched and essentially gamma phase free surface zone of a thickness of 5-50  mu m. <IMAGE>
Patent DE-60021755-T2 (DE)
Inventor: HOLLSTROEM MAGNUS
IPC: H04M1/72415
Filed: 2000-12-01
Granted: 2006-04-13
Abstract: A server device (31, 41, 51) has a programmable controller, a memory coupled to the controller, and a server program stored in the memory and executable by the controller. A first interface of the server device provides a first communication link (32, 42, 52) to a portable telecommunication apparatus (1). A second interface connects the server device to an electronic utility device (30, 40, 50). The server program communicates with a client program in the portable telecommunication apparatus through the first interface. The server program also communicates with the electronic utility device through the second interface, so that digital information may be transferred between the portable telecommunication apparatus and the electronic utility device.
Patent DE-60022881-T2 (DE)
Inventor: O'NEILL ALAN WILLIAM
IPC: H04L45/02
Filed: 2000-07-19
Granted: 2006-07-06
Abstract: Packets in a packet switching network are routed along a routing path defined by data held in packet switching nodes. One or more network addresses are assigned to a first access node as home addresses. A first home address is allocated to a first mobile node with at least one routing path being directed to a first access node for that first home address. Routing in the packet switched infrastructure is altered when the first mobile node receives service from a second access node by transmitting routing update messages to a limited subset of localized packet switching nodes such that at least one routing path in the infrastructure is directed to the second access node for the first home address. Routing in the infrastructure is subsequently altered such that at least one routing path is directed to the first access node for the first home address, and the first home address is allocated to a second mobile node served by the first access node.
Patent DE-60025005-T2 (DE)
Inventor: MATSUMOTO HITOSHI
IPC: C08F297/02
Filed: 2000-09-01
Granted: 2006-06-22
Abstract: An ESCAP type polymer which has a controlled structure wherein the groups protecting phenolic hydroxyl groups have been selectively or partly eliminated or decomposed with an acid and no carboxylic acid residues are contained and which is a narrow-disperse polymer and is suitable for use as a material for a chemical amplification type resist for excimer lasers which has excellent resolution. The process is characterized by subjecting either an alkenylphenol in which the phenolic hydroxyl group has been protected or the alkenylphenol and a vinylaromatic compound to anionic polymerisation together with a (meth)acrylic ester to give a block copolymer and eliminating only a given proportion of the groups protecting the phenolic hydroxyl groups from the block copolymer with an acid reagent. Thus, an alkenylphenol copolymer is synthesized which has a ratio of the weight-average molecular weight (Mw) to the number-average molecular weight (Mn), (Mw/Mn), of 1.00 to 1.50 and has no carboxylic acid residues.
Patent DE-60103666-T2 (DE)
Inventor: MOTHA KSHAMA
IPC: C08L51/06
Filed: 2001-12-19
Granted: 2005-06-16
Abstract: The invention refers to the use of a polymer material comprising a nanofiller containing polyolefin composition for the production of articles with an improved balance of mechanical, thermomechanical and optical properties.
Patent DE-60106247-T2 (DE)
Inventor: STANGHAMMAR TAGE
IPC: F24H1/26
Filed: 2001-06-08
Granted: 2006-02-23
Abstract: Hot water boiler with a flow heater for tap water, comprising a combustion chamber (4), an outlet for heating water from a gap-shaped passage (22) arranged around the combustion chamber (4), a tube coil (18) for tap water arranged in said passage, and an inlet (9) for return heating water. The boiler comprises a preheater (11) for return heating water arranged in the combustion chamber (4). The preheater has an outlet line (13) which conducts preheated heating water out of the combustion chamber (4) to the lower part of the boiler, from where it passes upward in the gap-shaped passage (22) surrounding the combustion chamber (4) while being heated by the combustion chamber (4) and transferring heat to the tap water. A high production of hot tap water is thus achieved.
Patent DE-60106872-T2 (DE)
Inventor: CHAVEZ PABLO
IPC: G01R15/24
Filed: 2001-01-30
Granted: 2005-12-29
Abstract: A voltage sensor for measuring the voltage on high voltage lines is formed by an electrically isolating-section of material with resistive shielding (RS) that structures the electric field generated by a voltage difference between the two ends of the isolating-section and provides shielding of the internal electric field from sources of electric field interference external to the voltage sensor. At least one electric field sensor is provided to sense the electric field in the isolating-section the output(s) of which is(are) used to infer the voltage difference.
Patent DE-60108355-T2 (DE)
Inventor: SAKA YASUHIRO
IPC: C07D205/04
Filed: 2001-02-02
Granted: 2005-06-16
Abstract: The invention provides a process for producing optically active azetidine-2-carboxylic acid with good efficiency, expedience, and commercial advantage, which comprises cyclizing an optically active 4-amino-2-halogenobutyric acid in an optical yield of as high as 90% or more. It is a process for producing optically active azetidine-2-carboxylic acid of the general formula (2), in which * denotes an asymmetric carbon atom, which comprises cyclizing an optically active 4-amino-2-halogenobutyric acid of the general formula (1),in which X represents a halogen atom and * denotes an asymmetric carbon atom, in the presence of an oxide of an alkaline earth metal, a hydroxide of an alkaline earth metal excepting barium, or an organic amine. <CHEM>
Patent DE-60110720-T2 (DE)
Inventor: HATTORI SHOZO
IPC: B29C49/04
Filed: 2001-10-04
Granted: 2006-01-12
Abstract: A liquid container (1) includes an outer wall (11) constituting a casing; an inner wall (12) constituting an inner bladder for accommodating liquid, the inner bladder having outer shape substantially equivalent to an inner shape of the outer wall, and the inner bladder having a flexibility and being separable from the casing; a pinch-off portion (13) where portions of the inner wall are welded to each other and are pinched by the outer wall to be supported by the outer wall; wherein the inner wall includes a thicker portion having a larger thickness than another portion of the inner wall, at both sides of the welded portion; and a cavity (20a,20b) provided between an outer surface of the thicker portion of the inner wall and an inner surface of a corresponding portion of an inner surface of the outer wall. <IMAGE>
Patent DE-60111501-T2 (DE)
Inventor: GRABENKORT W
IPC: A61M5/315
Filed: 2001-02-20
Granted: 2006-05-18
Abstract: A syringe may include various forms of a releasable stop adapted to selectively limit the travel of the syringe plunger within the syringe barrel such that a first amount of therapeutic substance may be discharged from the syringe while a residual supply of the therapeutic substance remains in the syringe. Movement of the plunger is permitted to displace the residual supply of fluid from the barrel. Syringes according to the invention find particular application as diluent syringes in a wet/dry drug delivery syringe system having two cooperating syringe barrels in which the residual supply of diluent in the diluent syringe may be used to flush additional and otherwise wasted drug from a drug syringe barrel.
Patent DE-60111842-T2 (DE)
Inventor: DAVIDSON IAN DAVID FARQUHAR
IPC: E21B43/243
Filed: 2001-04-20
Granted: 2006-05-24
Abstract: A process for in situ gasification of mineral oil in a subterranean formation comprises running a tool having a controllable thermal device therein from a surface production facility down to the subterranean formation, bringing said tool into operational proximity with the mineral oil in said subterranean formation, and activating the tool to operate the thermal device within a predetermined temperature range to generate gases or oily vapours from said mineral oil, which permits either an enhanced oil recovery (EOR) method with reduced water contamination, or a gas production process (GPP) which is useful in reducing environmental risks normally associated with transport of crude oil.
Patent DE-60112224-T2 (DE)
Inventor: KOKKINEN HEIKKI
IPC: G06Q10/00
Filed: 2001-11-23
Granted: 2006-04-20
Abstract: A server (12) suitable for a vehicle (14) having a first wireless interface (55) providing a connection on a customer basis for local user terminals (16) to the server, to enable access to local content on the server, and a second wireless interface (60) providing a connection to an external mobile network (62), to enable access to remote content on remote servers. Preferably, the vehicle is a train car where passengers having a mobile terminal based on the first wireless interface may access the server. Preferably, the first wireless interface is based on Bluetooth. Preferably, the second wireless interface is W-CDMA. Preferably, the server comprises a second wireless interface (65) which may be a wireless LAN like HIPERLAN. <IMAGE>
Patent DE-60114647-T2 (DE)
Inventor: BROWN CHALMERS
IPC: C07C47/00
Filed: 2001-08-22
Granted: 2006-07-27
Abstract: A method of recovering metal values from an ion exchange resin to which a metal species is bound comprising contacting the reaction product stream with a basic ion exchange resin such that at least a part of the metal becomes bound to the resin as metal species and incinerating the resin to produce an ash containing the metal and/or oxides of the metal and separating the metal and/or oxides from the remainder of the ash. The method is useful for recovering rhodium catalyst values from homogeneously catalysed hydroformylation reactions of olefins with carbon monoxide.
Patent DE-60118412-T2 (DE)
Inventor: WESTRA R
IPC: H03M1/66
Filed: 2001-09-14
Granted: 2006-11-09
Abstract: A digital to analog converter (DAC) for converting a digital signal (DS) having a maximum voltage range which corresponds to a first supply voltage (UL) into an analog signal (Uout) having a maximum voltage range which corresponds to a second supply voltage (UH). The first supply voltage (UL) is offered between a first supply terminal (VSS) and a second supply terminal (VDDL). The second supply voltage (UH) is offered between the first supply terminal (VSS) and a third supply terminal (VDDH). The digital to analog converter (DAC) comprises conversion resistors (RCNV0-RCNVn) and coupling means (CPL) for coupling a number of said conversion resistors (RCNV2-RCNVn) in between the first supply terminal (VSS) and an output terminal (OUT), and for coupling the remainder of said conversion resistors (RCNV0-RCNV1) in between the third supply terminal (VDDH) and the output terminal (OUT). The value of said number depends on the data content of the digital signal (DS). Digital to analog converters are generally implemented in ICs. For modern ICs there is a trend toward ever decreasing supply voltages. Often circuits implemented in new IC processes have to be able to interface with ICs processed in less modern processes which are generally operated on higher supply voltages. In the modern process, therefore, circuits designed in modern ICs have to cope with voltages which are above the maximum specification for their transistors or other components. The DA-converter (DAC) mentioned above fulfils this requirement by the fact that material, such as polycrystalline silicon, is used for the conversion resistors (RCNV2-RCNVn), which material can cope with relatively high voltages, and furthermore by the fact that only the coupling means (CPL) have to be designed to cope with relatively high voltages.
Patent DE-60124112-T2 (DE)
Inventor: OPHEY G
IPC: G02B5/30
Filed: 2001-07-25
Granted: 2007-06-06
Abstract: A display device comprising at least one light modulation panel and at least two projection elements, wherein, in operation, an image having a relatively high resolution in a relatively small field of view is presented to a first eye by means of the first projection element, while an image having a relatively low resolution in a relatively large field of view is presented to a second eye by means of the second projection element. The second projection element is provided with means for masking a part of the large field of view, which part substantially corresponds to the small field of view.
Patent DE-60124386-T2 (DE)
Inventor: MASUOKA SHIGERU
IPC: C09D193/04
Filed: 2001-04-24
Granted: 2007-10-04
Abstract: According to this invention:   excellent antifouling paint films exhibiting such a preferable film-erosion property and superior antifouling activity that can steadily be maintained for a very long period of time even from the beginning when used in sea-water and having outstanding basic paint-film properties and high water-resistance can be provided; antifouling paint by using of which such excellent antifouling paint films can be formed, which can stably be preserved for long, can be provided; structures used in or in contact with water such as sea-warter, having an antifouling paint film(s) formed by using the antifouling paint of this invention on its surface(s), by using of which such antifouling paint films which can easily prevent the attachment of marine organisms, such as barnacles and the like, to their surface(s) can be provided; and methods for preventing from fouling to prevent the attachment of marine organisms, such as barnacles and the like, to the surface(s) of the hull of ships or structures immersed in or in contact with sea-water can be provided.