baber/WOPTO huggingface dataset:
Patent AU-2020203826-B2 (AU)
Title: Compositions and Methods for Treating MPSI
Inventor: WILSON JAMES M
IPC: C12N7/01
Filed: 2020-06-10
Granted: 2022-09-15
Abstract: A vector have an expression cassette containing have a hDUA gene has a sequence of SEQ ID NO: 1 
or a sequence at least about 95% identical thereto which encodes a functional human alpha-L
iduronidase is provided. The vector may be a production vector or a rAAV8. Also provided are 
compositions containing these vectors and methods of treating MPSI and the symptoms associated 
with Hurler, Hurler-Scheie and Scheie syndromes.
Patent AU-2021200055-B2 (AU)
Title: Safety intravenous catheter with friction-based retention and disabling feature
Inventor: ISAACSON RAY S
IPC: A61M25/00
Filed: 2021-01-06
Granted: 2022-03-03
Abstract: A catheter and introducer needle assembly (200, 300, 400), including a flexible catheter 
and a catheter hub (204, 304, 404) having an uninterrupted outer surface portion (226, 326, 426), 
a Luer-connecting feature, and a disabling feature (232, 332, 432). The assembly includes an 
introducer needle (206, 306, 406) disposed in the catheter, a needle shield (210, 310, 410) having 
a resilient clip (212, 312, 412) adapted to flex between first and second positions in a plane 
perpendicular to the introducer needle. The resilient clip includes a cantilevered arm (220, 320, 
420) with a pawl (222, 322, 422). In the resilient clip's first position, the cantilevered arm is 
flexed so that the pawl frictionally contacts the catheter hub's uninterrupted outer surface portion 
and frictionally retains the needle shield with the catheter hub, and the pawl is axially aligned 
with and spaced apart from the disabling feature. In the second position, the pawl no longer 
frictionally contacts the hub's uninterrupted outer surface, thereby permitting needle shield 
displacement relative to the catheter hub.
WO 2016/109707 PCT/US2015/068122 
9/11 
N 
N q
Patent AU-2021204436-B2 (AU)
Title: Live fish processing system, and associated method
Inventor: PETTERSEN JØRN STÅLE
IPC: A01K61/95
Filed: 2021-06-29
Granted: 2023-06-29
Abstract: A fish handling unit (500) for processing live fish (1) is provided. Such fish handling 
unit (500) includes an inspection system (600) configured to inspect a plurality of live fish (1).  
A conveyor assembly (550) transports the live fish (1) to the inspection system (600). At least 
5 one robotic cell (510) is in communication with the inspection system (600). The robotic cell 
(510) has a controller configured to control operation thereof An end effector (800) is operably 
engaged with the robotic cell (510). The end effector interacts (800) with the live fish (1) 
moving along the conveyor assembly (550), based on information determined by the inspection 
system (600) and received by the controller. The end effector (800) may optionally be an 
o integrated gripper and injection assembly (850) capable of orientation and injection of the live 
fish (1). Associated devices and methods are also provided.  
Figure 10.
8/20 
868 870 
800 
844 
0 
869 845 
874 
824 
812 816 802 
8268 
830 
0 832 
834 806 
834 806 
832 08g~ 
FIG. 10 804 808
Patent AU-2021258023-B2 (AU)
Title: Methods for modulating protein galactosylation profiles of recombinant proteins using peracetyl galactose
Inventor: JORDAN MARTIN
IPC: C12P21/00
Filed: 2021-10-28
Granted: 2023-11-16
Abstract: The present invention relates to methods and compositions for modulating glycosylation profile, such 
as the galactosylation profile, of recombinant proteins expressed by mammalian host cells during the 
5 cell culture process by supplementing cell culture media with a peracetyl galactose.  
18200292_1 (GHMatters) P109979.AU.1
Patent AU-2021259899-B2 (AU)
Title: Austenitic stainless steel and spring
Inventor: SEKIMUKAI KOTARO
IPC: C22C38/00
Filed: 2021-03-29
Granted: 2023-06-29
Abstract: The present invention is an austenitic stainless steel which contains, on a mass basis, from 0.01% to 0.2% of C, 2% or less of Si, 3% or less of Mn, 0.035% or less of P, 0.03% or less of S, from 6% to 14% of Ni, from 20% to 26% of Cr, 3% or less of Mo, from 0.01% to 3% of Cu, 1% or less of Ti, 0.2% or less of Al, 0.1% or less of Ca, from 0.1% to 0.25% of N and 0.008% or less of O, with the balance being made up of Fe and impurities, wherein the E value obtained by formula (1) is -17.0 or more and the F value obtained by formula (2) is 0 or more.　(1): E = -0.33 × SFE + 0.25 × R
In formula (1), SFE = 25.7 + 2Ni + 410C – 0.9Cr – 77N – 13Si – 1.2 Mn (wherein the atomic symbols represent the contents (mass%) of the respective elements); and R represents the average crystal grain size (μm).
　(2): F = 1003O – 211Al – 158Ca – 79Ti
In formula (2), the atomic symbols represent the contents (mass%) of the respective elements.
Patent AU-2021262517-B2 (AU)
Title: Gas separation membranes
Inventor: DENG LIYUAN
IPC: B01D69/12
Filed: 2021-04-30
Granted: 2023-11-23
Abstract: A composite membrane suitable for separating a gas from a gas mixture comprising a selective layer coated on a support, wherein said selective layer comprises: a) a polymeric matrix comprising an amine polymer; b) a graphene oxide nanofiller; and c) a mobile carrier selected from an ionic liquid or an amino acid salt.
Patent AU-2021284990-B2 (AU)
Title: A flexible process for converting carbon dioxide, hydrogen, and methane into synthesis gas
Inventor: BALAJI SAYEE PRASAAD
IPC: C01B3/36
Filed: 2021-05-28
Granted: 2023-12-07
Abstract: The present invention relates to a process for converting feed streams selected from • (1) a gas stream comprising carbon dioxide and a hydrogen rich gas stream; • (2) a methane rich gas stream; and • (3) a combination of feed streams (1) and (2) into a product stream comprising carbon monoxide, water and hydrogen, the process comprising introducing feed streams selected from (1), (2) or (3) and oxygen into a reaction vessel, wherein the process comprises in switching mode performing a reverse water gas shift reaction introducing feed stream (1) and oxygen (method I) or a partial oxidation reaction introducing feed stream (2) and oxygen (method II) in the reaction vessel wherein no catalyst is present. The reaction vessel is provided with a burner located at the top of the reaction vessel, the burner comprising coaxial channels for the separate introduction of the different gas streams. During the switching mode from method I to method II or vice verse, the feed streams are gradually changed to the relevant feed streams, so that feed stream (3) is present in an intermediate phase, while also changing the temperature of the reactor to the desired temperature for the relevant method.
Patent JP-3481900-B2 (JP)
IPC: F16C11/04
Filed: 2000-03-14
Granted: 2003-12-22
Abstract: A nitrogenous heterocyclic compound represented by general formula (I) or a pharmacologically acceptable salt thereof, efficacious in treating various ischemic cardiac diseases, wherein ring A represents a benzene, pyridine or cyclohexane ring; ring B represents a pyridine, pyrimidine or imidazole ring; R<1>, R<2>, R<3> and R<4> represent each hydrogen, halogen, lower alkoxy, etc.; R<5> represents -NR<1><1>R<1><2> (wherein R<1><1> and R<1><2> represent each hydrogen, lower alkyl, etc.), etc.; and R<6> represents (a) (wherein R<1><9> represents hydrogen, lower alkyl, etc.; R<2><0>, R<2><1> and R<2><2> represent each hydrogen, halogen, hydroxy, etc.; and r represents an integer of 0.1 to 8), etc. <CHEM>
Patent JP-4716542-B2 (JP)
IPC: A61K39/102
Filed: 2000-05-30
Granted: 2011-07-06
Abstract: The present invention relates to live attenuated bacteria for use as a medicament. The invention also relates to vaccines based thereon that are useful for the prevention of microbial pathogenesis. Further, the invention relates to live attenuated recombinant bacteria carrying a heterologous gene and vaccines based thereon. Finally, the invention relates to methods for the preparation of such vaccines and bacteria.
Patent JP-3246507-B2 (JP)
Title: Ion removing means and ion removing method
Inventor: KOIKE TOSHIFUMI
IPC: D06F39/10
Filed: 2000-07-13
Granted: 2002-01-15
Abstract: PROBLEM TO BE SOLVED: To promptly supply water while removing cations contained in the water for washing by deciding the execution period of a reproduction processing in an ion removal means between a final rinsing process and the water supply start of the washing process of the next time. SOLUTION: After dehydration is ended, a microcomputer lights a light emitting diode and performs salt feeding display. Viewing it, a user opens the lid 30 of the ion removal means and feeds the prescribed amount of salt into the ion removal means in order to reproduce ion exchange resin 31. After prescribed time elapses, when the user presses a push button 34c, the salt water is made to flow down among the ion exchange resin 31 and discharged from a salt water discharge port 29c. Then, the ion exchange resin 31 is reproduced and calcium and magnesium are extracted in the salt water inversely. In such a manner, since the ion removal means is used by performing the reproduction processing, the water is promptly supplied while removing the cations contained in the water for washing.
Patent JP-3502604-B2 (JP)
IPC: H04L29/06
Filed: 2000-10-20
Granted: 2004-03-02
Abstract: The invention relates to methods for transmission of signalling data in cellular telecommunication networks. According to the invention, multiple radio bearers can be allocated for transferring signalling traffic, but all higher layer signalling is in any case taken through the RRC protocol. In the inventive method, MM and higher layer messages are sent using RRC DIRECT TRANSFER messages, but a separate RLC entity is set up for RRC DIRECT TRANSFER messages. In various embodiments of the invention, separate radio bearers can be set up for individual CN domains and/or upper layer protocols and/or for a group of RRC messages.
Patent JP-3525416-B2 (JP)
IPC: F16H61/02
Filed: 1998-11-16
Granted: 2004-05-10
Abstract: A controller has characteristic diagram memories and a fuzzy system which detects operating parameters of a motor vehicle and sets a transmission ratio with the aid of the characteristic diagram memory. A driver inputs plus and minus gear shift instructions via an input device. The driver instructions are evaluated during a driving operation by an adaptation circuit, and the shifting behavior of a transmission is adapted to a desired shifting behavior.
Patent JP-4494634-B2 (JP)
IPC: C12N15/09
Filed: 1999-05-12
Granted: 2010-06-30
Abstract: Transgenic plant cells and plants are described which, compared to wildtype cells and plants, exhibit an increased yield, in particular, an increased oil and/or starch content and which preferably synthesize a modified starch. The described plants exhibit an increase or a decrease of the plastidial ADP/ATP translocator activity.
Patent JP-4731018-B2 (JP)
IPC: G01N33/58
Filed: 2000-01-21
Granted: 2011-07-20
Abstract: The present invention relates to methods for coupling labels to particular target moieties. The coupling reactions of the present invention use temporal spacing of the reactants through phase change (i.e. by rapid freezing) to control the initiation and termination of reaction. This process results in a simplified and improved method for linking labels to specific binding moieties using N-hydroxysuccinimide chemistry. The present invention further relates to kits comprising all necessary components to easily and rapidly make protein conjugates.
Patent JP-4562920-B2 (JP)
IPC: A61B5/00
Filed: 2000-01-27
Granted: 2010-10-13
Abstract: A Holter-type monitor system includes a remotely located data receiving device, an analyte sensor for producing signal indicative of a characteristic of a user, and a Holter-type recording device. The Holter-type recording device includes a housing, a sensor connector, a processor, and a data port. The sensor connector receives the produced signals from the analyte sensor. The processor is coupled to the sensor connector and stores the signals from the analyte sensor for delivery to the remotely located data receiving device. The recording device is coupled to the processor for downloading the stored signals to the remotely located data receiving device. The data receiving device may be a characteristic monitor, a data receiver that provides data to another device, an RF programmer, a medication delivery device (such as an infusion pump), or the like.
Patent JP-4604161-B2 (JP)
IPC: A61K31/198
Filed: 2000-03-23
Granted: 2010-12-22
Abstract: The present invention provides phenylalanine derivatives that inhibit SH2 domain binding with a phosphoprotein. These derivatives include compounds of the formula: W—Y-(AA)n-Z wherein n is 0 to 15; Y is a phenylalanyl radical having a phenyl ring, an amine end, and a carboxyl end, the phenyl ring having one or more substituents, e.g., hydroxyl, carboxyl, formyl, carboxyalkyl, carboxyalkyloxy, dicarboxyalkyl, dicarboxyalkyloxy, dicarboxyhaloalkyl, dicarboxyhaloalkyloxy, and phosphonoalkyl, or phosphonohaloalkyl; W is a moiety attached to the nitrogen of Y and is, e.g., alkylcarbonyl, oxalyl, alkylaminooxalyl, arylaminooxalyl, arylalkylaminooxalyl, or alkoxyoxalyl; AA is an amino acid, the amine end of which is attached to the carboxyl end of Y; and Z is an arylalkylamino or arylheterocyclyl alkylamino; or a salt thereof; with the proviso that W is not arylalkylamino when the phenyl ring of phenylalanyl contains a phosphonoalkyl or phosphonohaloalkyl substituent at a position para to the alkylamido group and the ortho and meta positions are unsubstituted. The present invention further provides precursors suitable for preparing the phenylalanine derivatives and a method for the preparation of the precursors. The present invention further provides conjugates comprising a precursor and a conjugant that are covalently linked. These conjugates have biological and/or pharmacological properties.
Patent JP-4397557-B2 (JP)
IPC: H04B17/00
Filed: 2000-06-12
Granted: 2010-01-13
Abstract: An apparatus for testing a cellular phone comprising an RF signal generator ( 122 ) for transmitting an RF signal (RF 10 ) to said cellular phone, said RF signal generator receiving an input digital signal (DSIG 10 ) which determines the characteristics of the RF signal, means ( 112, 116 ) for providing said input digital signal comprising means for receiving a digital signal (DSIG 4 , DSIG 5 ), and at least one set of digital means, each set (A, B, C) of digital means comprising: a first digital means ( 200, 201, 202 ) to provide a first digital signal element relating to a first characteristic of said RF signal, and a second digital means (MA, MB, MC) to provide a second digital signal element relating to a second characteristic of said RF signal, and a means ( 203 ) to combine said digital signal elements to provide said input signal to said RF signal generator, said first, second and third characteristics comprise phase, amplitude and delay respectively. Thus the signal processing is carried out in the digital phase which is more easily controlled.
Patent JP-5268214-B2 (JP)
IPC: C12N15/117
Filed: 2000-08-14
Granted: 2013-08-21
Abstract: The invention provides methods for modulating the immune response caused by CpG-containing oligonucleotides. The methods according to the invention enable decreasing the immunostimulatory effect for antisense applications.
Patent JP-4973903-B2 (JP)
IPC: A61Q19/00
Filed: 2000-08-29
Granted: 2012-07-11
Abstract: The invention relates to a cosmetics composition comprising a thickener, a propellant, a surfactant and water, wherein the composition is contained in a container under a pressure of no more than 3 bar.
Patent JP-3867241-B2 (JP)
IPC: D06M11/00
Filed: 2000-07-05
Granted: 2007-01-10
Abstract: The invention relates to a plane metal structure which is especially useful for filtration. A metal fibre yarn is incorporated between the metal wires. The metal wire provides sufficient solidity for the plane structure. The metal fibre yarn is an excellent material for deep-bed filtration. In a preferred embodiment, the metal wire is woven together with the metal fibre yarn to form a tissue. The metal fibre yarn forms the weft and the metal wire the chain.
Patent JP-3894794-B2 (JP)
IPC: H04B7/005
Filed: 2001-02-26
Granted: 2007-03-22
Abstract: An out-of-synchronization condition for a Universal Mobile Telecommunications System (UMTS) is defined for a situation in which it may be difficult to distinguish an out-of-synchronization condition in a downlink dedicated channel from interference on that channel. A request is sent on an uplink from a user equipment (UE) to a base station transceiver (BST) for increased power on a downlink channel experiencing a possible frames out-of-synchronization condition, which may instead be a possible interference condition, so as to attempt to eliminate the possible interference. After a first selected period of time without eliminating the possible interference problem, the uplink is terminated unless a broadcast downlink channel is determined to be experiencing interference below a selected level, in which case the UE is allowed to continue to send the request for increased power. Only after a second selected period of time without eliminating the possible interference problem is the uplink terminated.
Patent JP-3907481-B2 (JP)
IPC: H04W24/00
Filed: 2002-01-16
Granted: 2007-04-18
Abstract: <P>PROBLEM TO BE SOLVED: To simplify an operating procedure of a dictionary registration during inputting a sentence to easily perform the dictionary registration in a portable communication terminal such as a cellular telephone.  <P>SOLUTION: A CPU 14 executes the dictionary registration processing during inputting the sentence such as a mail, selects a starting point and an end point of a character string to determine the same as a registration candidate, for example, when the pressing of soft keys S1, S2 as dictionary registration command is detected during inputting a mail sentence of a sentence input image plane, then the image plane is changed to a dictionary registration image plane in accordance with pressing a menu key M to display the registration candidate and a reading input area on the same image plane, and the presence or absence of the registration of the same character string is detected in accordance with the determination of the reading input, so that the character string is registered in the dictionary as a first conversion candidate, when the registration does not exist, and the determination is canceled when the registration exists.  <P>COPYRIGHT: (C)2003,JPO
Patent JP-4975936-B2 (JP)
IPC: C07C249/08
Filed: 2002-08-28
Granted: 2012-07-11
Abstract: Processing of a reaction mixture formed by ammoxidation of a ketone with hydrogen peroxide and ammonia using a titanium-containing catalyst in homogeneous solution comprises separation of the catalyst, separation of the product, discarding the water of reaction and recycling of the solvent. The ketone-oxime product is separated by a liquid-liquid extraction in a ternary solvent system.
Patent JP-4165744-B2 (JP)
IPC: B64C1/06
Filed: 2001-06-15
Granted: 2008-10-15
Abstract: A method and apparatus for the manufacture of fiber reinforced structures including the tooling and its use in the manufacture of reinforced structures. The apparatus comprises a conformable locating aperture system (CLAS) used for the formation of composite structures. The method includes the use in the formation of a structure and the method of manufacture of a structure.
Patent JP-4965053-B2 (JP)
IPC: A61M37/00
Filed: 2001-07-18
Granted: 2012-07-04
Abstract: The present invention relates to efficient devices for administration of pharmaceutical agents into the skin of the human body. In particular the present invention provides devices for vaccination into the skin. The present invention provides a pharmaceutical agent delivery device having skin-piercing portion comprising a solid reservoir medium containing the pharmaceutical agent, wherein the reservoir medium is coated onto the skin piercing portion. Alternatively, the skin piercing portion may consist of the solid pharmaceutical agent reservoir medium. The pharmaceutical delivery devices are proportioned such that agent is delivered into defined layers of the skin, and preferred delivery devices comprise skin-piercing portions that deliver the pharmaceutical agent into the epithelium or the dermis. Preferred reservoir media comprise sugars, and in particular stabilising sugars that form a glass such as lactose, raffinose, trehalose or sucrose. Furthermore, vaccine delivery devices for administration of vaccines into the skin are provided, methods of their manufacture, and their use in medicine.
Patent JP-4868692-B2 (JP)
IPC: C12Q1/04
Filed: 2001-08-07
Granted: 2012-02-01
Abstract: The invention concerns the use of whole or part of the GRF1 protein, or of cells expressing whole or part of the GRF1 protein, in methods for detecting compounds for preventing and/or treating pathologies or disorders of the central nervous system involving neuronal death, such as apoptosis, or related to leptin metabolism. The pathologies of the central nervous system are in particular cerebral ischemia, Parkinson's disease or Alzheimer's disease.
Patent JP-4820046-B2 (JP)
IPC: A41D13/018
Filed: 2001-09-05
Granted: 2011-11-24
Abstract: The present invention concerns a multi parts garment having multiple means for the protection of motor bikers and/or of athletes practicing various sports against traumas from accidental falls and violent impacts; said garment has in cooperation a jacket having seam sections in preset tearing yarn, a gilet internally joined thereto and integrally associated to plural pockets in a fabric having a predetermined porosity and preset to be inflated by means of compressed gas bottles, which are advantageously overlapped, or adhering to a back protector protecting the spine and having a rigid polymeric structure, and an electronic unit, receiving pulses from acceleration sensors between the motor biker and the motor vehicle.
Patent JP-3647845-B2 (JP)
IPC: C07K14/16
Filed: 2001-09-26
Granted: 2005-05-18
Abstract: Disclosed herein are branched linkers of the formula: Zn-Y-Xm Wherein X, Y, Z, m, and n are as defined herein. The branched linkers are useful for producing conjugates that are used in diagnostic or therapeutic methods. Methods of producing the branched linkers are also described.
Patent JP-4067968-B2 (JP)
IPC: D06F75/18
Filed: 2002-02-14
Granted: 2008-03-26
Abstract: The invention relates to an iron (1) comprising a container of water (2) at atmospheric pressure. The water from the container flows through a nozzle between said container (2) and a heated and regulated steam chamber (5). An iron sole plate (3) forms the ironing surface and steam outlet holes (12) are arranged in said sole plate (3). The invention is characterized in that the iron (1) comprises means for creating a resonance or relaxation vibration in the water and steam circuit. The cyclic variation in the steam pressure is automatically maintained at an average pressure above that corresponding to the column of water available in the iron.
Patent JP-4081376-B2 (JP)
IPC: B01J20/283
Filed: 2002-04-15
Granted: 2008-04-23
Abstract: The present invention relates to a process for separating nucleic acid molecules, preferably open circular and supercoiled plasmid DNA and RNA molecules from each other, comprising the steps of providing a solution comprising the molecules; adsorbing the molecules to adsorbing groups on a carrier; and optionally washing the column with a suitable solution. The present process is especially suitable for large-scale isolation of supercoiled ccc DNA to be used in gene therapy.