baber/WOPTO huggingface dataset:
Patent EP-2649451-A1 (EP)
Title: Agtr1 en tant que marqueur pour polythérapies à base de bévacizumab
Inventor: DE LA HABA-RODRIGUEZ JUAN
IPC: G01N33/574
Filed: 2011-12-07
Abstract: Cette invention concerne des méthodes permettant d'évaluer la réactivité ou la sensibilité d'un patient à un inhibiteur d'angiogenèse tel qu'un agent se liant au VEGF, en particulier, le bévacizumab (Avastine ® ), soit seul, soit en association avec des séances de chimiothérapie, par détermination du niveau d'expression du récepteur de type 1 de l'angiotensine II (AGTR1) par rapport à un niveau témoin déterminé chez des patients souffrant d'un trouble prolifératif. En particulier, cette invention concerne une méthode permettant d'identifier un patient réagissant ou sensible au traitement par le bévacizumab, ledit patient étant suspecté de souffrir ou à risque de souffrir d'un trouble prolifératif. La méthode selon l'invention comprend l'étape consistant à déterminer le niveau d'expression du récepteur 1 de l'angiotensine II (AGTR1) dans un échantillon biologique dudit patient, un niveau d'expression accru d'AGTR1, comparé à un niveau témoin déterminé chez des patients souffrant de cancer, indiquant que ledit patient est réactif ou sensible au traitement par le bévacizumab. Cette invention concerne également une composition comprenant un inhibiteur d'angiogenèse tel qu'un agent se liant au VEGF, en particulier, le bévacizumab (Avastine ® ), pouvant être utilisée pour traiter un trouble prolifératif chez un patient identifié par la méthode proposée ci-décrite, l'utilisation d'un inhibiteur d'angiogenèse tel qu'un agent se liant au VEGF, en particulier, le bévacizumab (Avastine ® ) pour préparer une composition pharmaceutique destinée à traiter un trouble prolifératif chez un patient identifié par la méthode proposée ci-décrite, ainsi que des méthodes de traitement d'un trouble prolifératif comprenant l'administration d'une quantité efficace d'un inhibiteur d'angiogenèse tel qu'un agent se liant au VEGF, en particulier, le bévacizumab (Avastine ® ), à un sujet identifié par la méthode proposée ci-décrite.
Patent EP-2630545-A1 (EP)
Title: Verfahren zur reduzierung des energieverbrauchs einer walzwerkanlage, steuer- und/oder regelungseinrichtung für eine walzwerkanlage, maschinenlesbarer programmcode, speichermedium sowie eine walzwerkanlage
Inventor: SEHL JUERGEN
IPC: G05B15/02
Filed: 2011-12-06
Abstract: Verfahren zur Reduzierung des Energieverbrauchs einer Walzwerkanlage (2) umfassend eine ein- oder mehrteilige Walzstraße (6) sowie weitere elektrische Anlagenkomponenten (20 bis 28), die prozesstechnisch mit der Walzstraße (6) verbunden sind, wobei während einer unplanmäßigen Walzpause aufgrund eines Störfalls der Betrieb der Walzstraße (6) gestoppt wird und während der Walzpause mindestens eine der weiteren Anlagenkomponenten (20 bis 28) automatisch in einen Energiesparmodus heruntergefahren wird und wobei die Art der Störung identifiziert wird und in Abhängigkeit der Art der Störung die voraussichtliche Dauer der Walzpause bestimmt wird.
Patent EP-2739334-A1 (EP)
Title: Inhalateur de poudre
Inventor: ESTEVE VICTOR
IPC: A61M11/00
Filed: 2011-12-21
Abstract: La présente invention concerne des améliorations apportées à un inhalateur de poudre, constitué d'un logement de base (1), d'un réceptacle pour capsules (2) de type à encliquetage et d'un embout buccal amovible (4), à l'intérieur duquel se trouve un dispositif (7) destiné à ouvrir la capsule (C) contenant le médicament sous la forme de poudre, contenue dans une chambre de décomposition (10), avec des points de prise d'air (11 et 12) et un orifice de sortie (14) pour l'air mélangé avec la poudre, l'orifice de sortie (14) étant intégré au conduit (9) de l'embout buccal (4) ; le passage susmentionné (14) pour le mélange air/poudre situé entre le conduit (9) et la chambre (10) est restreint et suffisamment long pour entraîner deux effets dans la capsule (C) alors qu'elle tourne dans la chambre (10) durant l'inhalation : a) l'obstruction de la valve du passage (14) par la capsule (C), plus précisément par sa partie cylindrique, brièvement et par intermittence, cette obstruction du passage (14) étant répétée chaque fois que la capsule fait une moitié de tour (180°) ou qu'elle est alignée sur le passage (14) ; et b) impact de la capsule (C) par succion contre le haut de la chambre de décomposition (10) chaque fois que la capsule est alignée sur le passage (14) et que son obstruction est totale, cet impact étant suffisant pour neutraliser la compaction de la poudre au niveau des extrémités de la capsule (C) pendant sa rotation.
Patent EP-2654631-A1 (EP)
Title: Dispositif orthopédique
Inventor: FORBES JAMES
IPC: A61F5/01
Filed: 2011-12-19
Abstract: L'invention porte sur un dispositif orthopédique (10) qui a un panneau de corps principal (12) ayant une longueur longitudinale comportant une section transversale incurvée et des premier et second côtés (84, 86) opposés, et un panneau postérieur (14). Le panneau postérieur (14) est fixé aux premier et second côtés (84, 86) du panneau de corps principal, et est dimensionné longitudinalement plus court que le panneau de corps principal (12) dans un état non étiré. Le panneau postérieur (14) est fixé au panneau de corps principal (12) dans un état prétendu et s'étend sur la longueur longitudinale du panneau de corps principal (12) le long des premier et second côtés (84, 86) de celui-ci. Le dispositif orthopédique comprend un élément de contrefort (80) associé à une poche de contrefort (106) située autour d'une ouverture de rotule (48).
Patent EP-2676856-A1 (EP)
Inventor: AOKI TAKANORI
IPC: B60K6/485
Filed: 2011-02-15
Abstract: An electrically powered vehicle includes an electric motor, an internal combustion engine, a power storage device configured to input and output electric power to and from the electric motor, a power generation mechanism generating charge power for the power storage device by electric power generation using an output of an internal combustion engine, a charging state estimation unit for estimating a remaining capacity of the power storage device based on a state value of the power storage device, and a charge/discharge control unit for controlling charging and discharging of the power storage device based on the remaining capacity estimate value by the charging state estimation unit. The charge/discharge control unit includes a charge instruction unit for, in the case where the remaining capacity estimate value falls below a predetermined lower limit value, controlling the internal combustion engine to be in the load operation state to generate charge power and controlling the internal combustion engine to be in the no-load operation state or in the stopped state when it is determined that a prescribed charge termination condition is satisfied. The charge instruction unit sets the charge termination condition such that the charging time for the power storage device is shortened as the charge power that can be received by the power storage device in the present state is decreased.
Patent EP-2617072-A1 (EP)
Inventor: MAKANSI TAREK
IPC: H01L35/00
Filed: 2011-09-12
Abstract: Inexpensive, lightweight, flexible heating and cooling panels with highly distributed thermoelectric elements are provided. A thermoelectric "string" is described that may be woven or assembled into a variety of insulating panels such as seat cushions, mattresses, pillows, blankets, ceiling tiles, office partitions, under-desk panels, electronic enclosures, building walls, refrigerator walls, and heat conversion panels. The string contains spaced thermoelectric elements which are thermally and electrically connected to lengths of braided, meshed, stranded, foamed, or otherwise expandable and compressible conductor. The elements and a portion of compacted conductor are mounted within the insulating panel. On the outsides of the panel, the conductor is expanded to provide a very large surface area of contact with air or other medium for heat absorption on the cold side and for heat dissipation on the hot side.
Patent EP-2698776-A1 (EP)
Inventor: OKITA TOSHINORI
IPC: B60R21/00
Filed: 2011-04-11
Abstract: A vehicle control device 100 for starting a drive assist in accordance with relative positional relationship between a self vehicle and an object around the self vehicle, comprises a control value calculating part (10) which calculates a control value (CV) based on an inter-vehicular distance between the self vehicle and the object, a velocity of the self vehicle, a relative velocity of the object to the self vehicle, and an acceleration-related value (Ax) obtained based on at least one of an acceleration (Am) of the self vehicle and an acceleration (Ap) of the object; an acceleration-related value adjusting part (11) which adjusts the Ax by changing a degree of contribution of at least one of the Am and the Ap in the Ax in accordance with the Am; and a drive assist start judging part (12) which starts the drive assist if the CV is greater than a threshold value.
Patent EP-2638788-A1 (EP)
Inventor: MOSES EDWARD I
IPC: G21B1/17
Filed: 2011-11-08
Abstract: An architecture for a fusion power plant is disclosed. The plant includes a fusion chamber for producing neutrons from a fusion reaction, and a laser system in which lasers are arranged about a vacuum chamber to provide energy to the fusion chamber to initiate the fusion reaction. The beam paths between the lasers and the fusion chamber are configured to prevent neutrons from the fusion chamber from reaching the laser system at a level that would preclude human access to the laser system.
Patent EP-2653292-A1 (EP)
Inventor: OKADA KENYA
IPC: B32B5/02
Filed: 2011-12-01
Abstract: A carbon-fiber-reinforced plastic molded article which comprises a laminate with at least two layers including a unidirectionally continuous-carbon-fiber-reinforced sheet in which continuous carbon fiber bundles are arranged in a predetermined one direction, characterized in that, when the carbon fibers of an outermost unidirectionally continuous-carbon-fiber-reinforced sheet forming a design surface of the molded article are observed at the design surface, the area fraction of regions where the proportion of carbon fibers which are inclined at angles of 3° or more to the predetermined one direction is 0.5% or more is 20% or less relative to the whole area of the design surface. Thus, the present invention can provide a molded article in which carbon fibers are uniformly arranged at the design surface and which has an excellent appearance design property.
Patent EP-2653103-A1 (EP)
Inventor: CHA GEUN SIG
IPC: A61B5/151
Filed: 2011-09-20
Abstract: A releasing structure for a lancing device according to an exemplary embodiment of the present invention may include: a lancet body with a lancet at the front; a lancet holder mounted with the lancet body with the lancet at the front; a stem disposed behind the lancet holder and moving the lancet holder forward/backward; a rotary housing pushing/pulling the stem while turning forward at a predetermined angle about a rotational axis defined in the movement direction of the lancet; a torsion spring storing torque for turning the rotary housing forward at a predetermined angle; and a loading handle transmitting torque to the torsion spring while turning forward at a predetermined angle.
Patent EP-2656942-A1 (EP)
Title: Punch for cold backward extrusion forging
Inventor: NATSUI MASAYUKI
IPC: B21J5/06
Filed: 2011-12-19
Abstract: A punch 1 includes a forming land portion 2 formed in parallel with a punch axis 7, a forming R-portion 3 having an arc-shaped cross-section and formed continuously with the forming land portion 2 on a tip end side with respect to the forming land portion 2, and a recess portion 5 formed on a base end side with respect to the forming land portion 2 and having a diameter smaller than a diameter of the forming land portion 2. A Rockwell hardness HRF of the blank 20 is within a range of 65 to 105. The curvature radius R of the forming R-portion 3 of the punch 1 is set to be larger than the thickness L of a cylindrical peripheral wall portion 21 of the forged product 25. The length B of the forming land portion 2 of the punch 1 is set within a range of 0.05 to 0.15 mm. The recess width C of the recess portion 5 with respect to the forming land portion 2 of the punch 1 is set within a range of 0.15 to 1.0 mm.
Patent EP-2660362-A1 (EP)
Inventor: OKAZAKI TAKAHIRO
IPC: F16J9/26
Filed: 2011-12-27
Abstract: To provide a piston ring product in which hard particles are uniformly filled in cracks in hard chromium plating formed on the sliding surface and which has excellent long term use stability. To this end, a composite chromium plating film is provided, comprising a hard chromium plating film having crack-like grooves filled with hard particles, wherein the hard particles used are irregular particles having powder characteristics of an average circularity of 0.70 to 0.85, an average equivalent circle diameter of 6.0 µm or less and an aspect ratio of 1.3 or more. The composite chromium plating film is applied to the sliding surface of a piston ring product.
Patent EP-2661424-A1 (EP)
Title: Chemical compounds
Inventor: JEANMART STEPHANE ANDRE MARIE
IPC: C07D401/04
Filed: 2011-12-30
Abstract: Disclosed are cyclic dione derivatives represented by formula (I), wherein the substituents are as defined in the description. The preparation method, intermediate and use thereof are also provided.
Patent EP-2669987-A1 (EP)
Inventor: ICHIKAWA KOICHI
IPC: G01R31/36
Filed: 2011-01-24
Abstract: [PROBLEM] The deterioration state of an electric storage apparatus may be changed depending on the usage environment of the electric storage apparatus. 
     [SOLVING MEANS] An electric storage system includes an electric storage apparatus (10) connected to a load and performing charge and discharge, a temperature sensor (12) detecting the temperature of the electric storage apparatus in response to connection of the electric storage apparatus to the load, and a controller (30) estimating the deterioration state of the electric storage apparatus based on temperature information in a usage environment of the electric storage apparatus. The controller obtains a temperature distribution of the electric storage apparatus based on an output from the temperature sensor when the electric storage apparatus is connected to the load, and specifies a usage environment of the electric storage apparatus associated with the obtained temperature distribution.
Patent EP-2476890-A1 (EP)
Inventor: DEWES MARKUS
IPC: F02M37/00
Filed: 2012-01-12
Abstract: The device (1) has a fuel container (9) for supplying fuel to a fuel consumer (5) over a fuel pipe (11). A pretensioning device (13) pretensions the fuel in the pipe and has an energy storage (19). A control unit (23) e.g. 2/2-way-switching valve, controls a connection pipe (25) between the pretensioning device and the fuel pipe such that the connection pipe is partially locked or released. The energy storage is designed in the form of a gas storage and made from compressible material, and a fuel conveyor device has two conveyor units (15, 21) e.g. low pressure and high-pressure pumps.
Patent EP-2607153-A1 (EP)
Inventor: LEESE GAVIN PAUL
IPC: B60N2/90
Filed: 2012-03-20
Abstract: The object to provide a user-friendly handling for the adjustment of the height of components, in particular head rests is solved by the device for height adjustment of a component of a seat in accordance with the invention which consists of a carrier element carrying the component, a locking element designed and arranged to prohibit height adjustability in a first position and to permit height adjustability in a second position, wherein the locking element is connected with an adjusting element via a motion link, and the adjusting element is pulled upward by pulling means so as to transfer the locking element from the first position to the second position.
Patent EP-2656785-A1 (EP)
Inventor: MOISSL ULRICH DR
IPC: A61B5/053
Filed: 2012-04-26
Abstract: The present invention relates to electrodes (10) for a bio-impedance measuring device (30) or a body composition monitor, the electrodes (10) being integral with or being attached to a surface of at least one device belonging to a group of electronic and/or non-electronic devices used in the preparation of a dialysis treatment or during dialysis, in particular during peritoneal dialysis, the group preferably consisting of organizers (20) of a continuous ambulatory peritoneal dialysis system (CAPD), automated peritoneal dialysis devices, automated peritoneal dialysis-cyclers (APD-Cycler) (40), bioelectrical impedance analyzers (BIA) (30), body composition monitors (BCM), hand-held electrodes holders (50) for the electrodes, and dialysis apparatuses. The invention also relates to devices and methods used during dialysis.
Patent EP-2601991-A1 (EP)
Inventor: KAWAMURA HIDEAKI
IPC: A61M5/31
Filed: 2012-10-23
Abstract: A medicine syringe (1) has a syringe barrel (2), piston (3) and plunger rod (4). The syringe barrel is provided with a cylindrical main body (21) defining therein a chamber (211) to be filled with a medical solution, and an injection nozzle portion (22) formed at an end portion of the main body and defining therein a hollow bore (221) in communication with the chamber. The chamber and hollow bore have a total capacity of not greater than 0.5 mL. The chamber and hollow bore are formed such that the piston is slidable in a range of from 20 to 100 mm and is allowed to slide liquid-tight into the hollow bore beyond the chamber.
Patent EP-2465871-A1 (EP)
Inventor: YAN WEI
IPC: C07K16/00
Filed: 2006-10-23
Abstract: The present invention relates to monovalent antibody, methods of making thereof and therapeutic uses thereof. In particular, the present invention provides a heterodimeric polypeptide comprising an immunoglobulin heavy chain and a fusion protein comprising an immunoglobulin light chain and an Fc molecule.
Patent EP-2495121-A1 (EP)
Inventor: INABA RYUTARO
IPC: B60K15/067
Filed: 2012-03-01
Abstract: A mounting structure wherein a buffer member has a body portion, and a leg portion which is extended from the body portion and engaged with a recess, wherein the body portion has a plurality of first convex portions which are arranged around a center axis of the body portion at regular intervals and abut against a vehicle body, a plurality of first concave portions each of which is formed between the adjacent first convex portions, a plurality of second convex portions which are arranged around the center axis of the body portion 61 at regular intervals and abut the fuel tank, and a plurality of second concave portions each of which is formed between the adjacent second convex portions, and wherein the first convex portion is formed corresponding to the second concave portion, and the second convex portion is formed corresponding to the first concave portion, is provided.
Patent EP-2639446-A1 (EP)
Inventor: HEISE VOLKER
IPC: F02P3/04
Filed: 2012-03-16
Abstract: An ignition system for an internal combustion engine comprises an ignition transformer with two primary windings (L P1 , L P2 ). The ignition system is designed to generate, for a given ignition event, a unipolar current (I SEC ) through the secondary winding (L SEC ) by way of a control circuit (20) that is configured to first energize and deenergize the first primary winding (L P1 ) to establish a first electrical arc across the spark-plug electrodes (14) and, when the current (I SEC ) in the secondary winding reaches, or drops below, a current threshold (I SEC_TH ), repeatedly energizes and deenergizes the second primary winding (L P2 ) to establish a plurality of second current pulses across the electrodes in order to maintain the burn phase.
Patent EP-2541600-A1 (EP)
Title: Non-volatile semiconductor memory cell with dual functions
Inventor: LU HAU-YAN
IPC: H01L29/423
Filed: 2012-03-23
Abstract: A non-volatile semiconductor memory cell (300) with dual functions includes a substrate, a first gate (313-1), a second gate (313-2), a third gate (313-3), a charge storage layer (314), a first diffusion region (311-1), a second diffusion region (311-2), and a third diffusion region (311-3). The second gate (313-2) and the third gate (313-3) are used for receiving a first voltage corresponding to a one-time programming function of the dual function and a second voltage corresponding to a multi-time programming function of the dual function. The first diffusion region (311-1) is used for receiving a third voltage corresponding to the one-time programming function and a fourth voltage corresponding to the multi-time programming function. The second diffusion region (311-2) is used for receiving a fifth voltage corresponding to the multi-time programming function.
Patent EP-2514498-A1 (EP)
Inventor: MAYER LUDWIG
IPC: B01D25/21
Filed: 2012-04-19
Abstract: The filter cloth (2) has a woven fabric turned downwardly in an edge region (22) such that a filter cloth region (23a) is arranged on another filter cloth region (23b). The both regions are partially connected with each other by individual welding connections that are spaced from each other. The fabric is made of thermoplastic material e.g. polypropylene, polyethylene terephthalate and polyamide, and/or organic fibers e.g. cotton and glass- or carbon fibers. An accommodating space (24) is formed in the edge region to accommodate a flexible accommodating body (25) e.g. O-ring and string. An independent claim is also included for a filter plate.
Patent EP-2532576-A1 (EP)
Inventor: VELTMAN ANDRE
IPC: B62M6/45
Filed: 2012-06-11
Abstract: The invention relates to a cycle, in particular a bicycle (1), comprising a frame (2), wheels (3,4), an axle (5), pedals (6) mounted on the axle (5) via cranks (7), a transmission (8,9) coupling the axle (5) to at least one of the wheels (4), an electric motor (10) for driving at least one of the wheels (4), a means (13) for measuring the speed of the cycle (1), and a controller (11) for driving the motor (10) in dependence of the torque exerted on the axle (5). The means (13) for measuring the speed of the cycle (1) are coupled to a module (14) that is arranged to estimate, based on variations in the speed of the cycle (1), a parameter proportional to the torque exerted on the axle (5).
Patent EP-2572714-A1 (EP)
Inventor: NOELLE RANDOLPH
IPC: A61K39/00
Filed: 2003-12-30
Abstract: The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen.
Patent EP-2508529-A1 (EP)
Inventor: JENDRISAK JEROME
IPC: C07H21/00
Filed: 2009-10-24
Abstract: The present invention provides methods, compositions and kits for using a transposase and a transposon end for generating extensive fragmentation and 5'-tagging of double-stranded target DNA  in vitro,  then using a DNA polymerase for generating 5'- and 3'-tagged single-stranded DNA fragments without performing a PCR amplification reaction, wherein the first tag on the 5'-ends exhibits the sequence of the transferred transposon end and optionally, an additional arbitrary sequence, and the second tag on the 3'-ends exhibits a different sequence from the sequence exhibited by the first tag. The method is useful for generating 5'- and 3'-tagged DNA fragments for use in a variety of processes, including processes for metagenomic analysis of DNA in environmental samples, copy number variation (CNV) analysis of DNA, and comparative genomic sequencing (CGS), including massively parallel DNA sequencing (so-called "next-generation sequencing.)