baber/WOPTO huggingface dataset:
Patent NZ-527221-A (NZ)
Title: A negative-sense single stranded RNA virus causing respiratory tract illness in susceptible mammals
Inventor: DE JONG JAN CORNELIUS
IPC: C07K/
Filed: 2002-01-18
Abstract: An isolated mammalian negative-sense single stranded RNA virus (MPV) belonging to the sub-family Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus. Also described are antibodies directed against MPV, a method for identifying a viral isolate as a MPV, a diagnostic kit, and a pharmaceutical composition comprising the virus.
Patent NZ-528166-A (NZ)
Title: A method for preparing a seeded dermal equivalent
Inventor: COMER ALLEN
IPC: C12Q1/68
Filed: 2002-03-01
Abstract: A process for preparing a seeded dermal equivalent comprising: a. providing a dermal equivalent, keratinocytes, and culture media having an air interface; b. culturing the dermal equivalent in the culture media; c. lifting the dermal equivalent to the air interface to provide a lifted dermal equivalent; d. seeding the dermal equivalent with the keratinocytes to provide a seeded dermal equivalent; e. incubating the seeded dermal skin equivalent under conditions such that a skin equivalent is formed.
Patent NZ-534241-A (NZ)
Title: Water heater heat trap apparatus
Inventor: HICKS KENNETH J
IPC: F24H9/12
Filed: 2004-04-13
Abstract: Convective heat traps (12a) are installed at the cold water inlet and hot water outlet (22) of a water heater. Each heat trap has a tubular body (42) with two axially spaced apart resilient flapper members transversely extending across the interior of the body and being hinged on opposite sides thereof. The heat trap at the cold water inlet is coaxially disposed within a dip tube. In one alternate structure, flapper members are mounted directly on the dip tube, and in another alternate structure an external annular seat element is mounted on the dip tube or heat trap body, with a flapper member being integrally formed with the seal element. (62) Divided Out of 532272
Patent NZ-536067-A (NZ)
Title: Paper machine fabric with separate fabrics and number of machine direction yarns being larger on machine side compared to paper side
Inventor: TAIPALE SEPPO
IPC: D21F1/10
Filed: 2003-05-02
Abstract: A paper machine fabric is disclosed comprising at least two separate layers formed using at least two separate yarn systems: one constituting the paper side and comprising machine direction and cross machine direction yarns (1, 2) and the other constituting the machine side and comprising machine direction and cross machine direction yarns, the yarn systems being arranged to form independent structures in both directions of the fabric. The structures are bound together with binder yarns (5), a binder yarn (5) being arranged to form part of the weave of a layer on the paper side surface and arranged to be interwoven with a layer of the machine side by being interwoven under at least one yarn in the machine side layer. The number of machine direction yarns in the layer constituting the machine side is larger than the number of machine direction yarns (1) in the layer constituting the paper side.
Patent NZ-536959-A (NZ)
Title: Methods and compositions useful for the therapeutic treatment of central nervous system disorders related to or affected by the 5-HT6 receptor
Inventor: BERNOTAS RONALD CHARLES
IPC: A61P25/00
Filed: 2003-06-03
Abstract: Described is a compound of formula (I) and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor, use of said compound in the preparation of a medicament for the treatment of a disorder of the central nervous system related to or affected by the 5-HT6 receptor and a pharmaceutical composition comprising said compound.
Patent NZ-540411-A (NZ)
Title: Device and method for needleless syringe
Inventor: KENDALL MARK ANTHONY FERNANCE
IPC: A61M5/24
Filed: 2002-07-25
Abstract: A particle retention assembly (60) comprising: a particle retention chamber (71) bounded by an upstream closure and a downstream closure; a first duct (43) providing a first gas flow path into the chamber; wherein the first duct is arranged, in use, to create a first swirl of gas in the particle retention chamber. A second duct (43) provides a second gas flow path into the chamber, the second duct being arranged, in use, to create a second swirl of gas in the particle retention chamber. The first and second ducts are arranged to direct the first and second swirls in substantially different directions.
Patent NZ-540984-A (NZ)
Title: A louvre window with partially opening louvres
Inventor: HEADS FRANCIS XAVIER
Filed: 2005-06-28
Abstract: A louver window which has a window surround frame, a plurality of louvres pivotally mounted to the window surround frame, and a handle (15) which is operatively associated with the louvers such that rotation of the handle causes rotation of at least some of the louvres between a closed position and an open position. The louvre window contains stop means (16) to prevent the louvres from opening to a fully open substantially horizontal position, the stop means being associated with the handle to restrict operation of the handle.
Patent NZ-541194-A (NZ)
Title: Multilayer oxygen scavenging film with high slip properties comprising siloxane
Inventor: SCHWARK DWIGHT W
IPC: B32B27/18
Filed: 2004-01-23
Abstract: Disclosed is a multilayer film comprising: (a) a first and second outer layer each comprising a polymer; and (b) an internal layer comprising an oxygen scavenger; wherein at least one of the first and second outer layers comprises a blend of: (i) a polymer (ii) a siloxane having a viscosity of from 1x107 centistokes to 5x107 centistokes, and (iii) an antiblock agent; wherein the kinetic coefficient of friction (film surface to film surface) of the film is 0.5 or less (ASTM D1894-99); and wherein the average oxygen scavenging rate of the film is at least 20 cc/m2/day four days after an oxygen scavenging property of the film is activated.
Patent NZ-541424-A (NZ)
Title: Novel method for synthesising perindopril and the pharmaceutically acceptable salt thereof
Inventor: DUBUFFET THIERRY
IPC: C07K5/02
Filed: 2004-02-27
Abstract: Disclosed is a process for the synthesis of perindopril of formula (I), involving reacting 1-(1-cyclohexen-1-yl)-pyrrolidine with a serine derivative; deprotecting the obtained cyclohexyl-serine derivative, cyclizing and dehydrating; reacting the obtained hexahydroindole derivative with N-((S)-1-ethoxycarbonyl-butyl)-(S)-alanine and hydrogenating and deprotecting the obtained hexahydroindole derivative.
Patent NZ-542432-A (NZ)
Title: Crystalline N-formyl hydroxylamine compounds
Inventor: MULLER MARTIN
IPC: A61K/
Filed: 2004-04-01
Abstract: Disclosed are crystalline salts of 1-{2-R-[(formyl-hydroxy-amino)-methyl]-hexanoyl}-pyrrolidine-2-S-carboxylic acid (5-fluoro-1-oxy-pyridin-2-yl)-amide of formula (I), including crystalline magnesium salts. The crystalline salts are useful for treating and/or preventing an infectious disorder.
Patent NZ-544166-A (NZ)
Title: Folded metal window side flashing
Inventor: KENNEDY ANTHONY DAVID
Filed: 2005-12-15
Abstract: A metal building flashing element has faces 1, 2, 3, 4, 5 with length wide folds from face to face at the 90 degree and 180 degree angles as shown. The width of the faces is selected to suit the application, and the flashing is particularly suitable for use as a vertical flashing between and separating a window frame and wall cladding.
Patent NZ-545594-A (NZ)
Title: Yeast cell walls for the treatment or prevention of hyperglycemia or for the stabilisation of glycemia
Inventor: LESAFFRE LUCIEN
IPC: A61K31/716
Filed: 2004-08-10
Abstract: Provided is the use of yeast cell walls in the preparation of a therapeutic composition for the treatment of hyperglycemia, wherein said yeast cell walls are from yeast of the species Saccharomyces cerevisiae and have: a total glucan and mannan content of 40-45% by mass on a dry matter basis, and a glycogen content of less than 10.0% by mass on a dry matter basis.
Patent NZ-548651-A (NZ)
Title: Method and device for measuring the texture of cooked grains
Inventor: IYENGAR NARASIMHA HAMPAPURA VE
IPC: G01N3/42
Filed: 2003-12-31
Abstract: A method and device for assessing end point of cooking of dhal and rice with good reproducibility are disclosed. Pulses are generally consumed as dhals after cooking to soft texture. Measurement of end point of cooking of dhals, rice etc is very subjective and current methods are not very satisfactory. An innovative device and an objective method for carrying out the same were developed. This works on the principle of determining the "spread area" during progressive cooking for dhals as well as rice, and reading the cooking time form a graph plotted. The device developed for the purpose can be used to exert the desired force for pressing the cooked grain and the area to which the grain spreads is determined by counting the number of squares from an appropriate graph sheet as "spread area" is plotted against the period of cooking a progressive increase was observed.; The time at which, there was a sudden increase in the spread area or when a change in the slope of the curve (sudden deflection / steadiness) occurred was considered as cooking time of the sample (dhal / rice) being cooked. The method now reported corroborated well with the standard instrumental methods. This invention provides an objective and reliable method for assessing end point of cooking of dhal and rice with good reproducibility.
Patent NZ-549224-A (NZ)
Title: Process for the preparation of tryptase inhibitors
Inventor: GRAF CLAUSE-DIETER
IPC: C07D211/02
Filed: 2005-02-18
Abstract: Disclosed is a process for the preparation of a tryptase inhibitor of the formula I wherein the substituents are disclosed within the specification comprising a) treating a phenylenthynylsilane compound of formula II in a solvent with an alkali metal hydroxide, carbonate or alcoholate or an alkaline earth metal alcoholate, to form a solution of a phenylethyne of the formula III; b) combining the resulting solution of the phenylethyne with a compound of the formula IV wherein X is bromo or iodo and Boc is tert-butoxycarbonyl, in the presence of homogeneous palladium catalyst, a cuprous salt, and a hindered amine in a solvent to form a protected compound of the formula V and c) removal of the tert-butoxycarbonyl group in the compound of formula V to provide a compound of formula I or its salt. Also disclosed are number of intermediates.
Patent NZ-549331-A (NZ)
Title: Imidazole compounds for the treatment of neurodegenerative disorders
Inventor: BRODNEY MICHAEL AARON
IPC: C07D403/06
Filed: 2005-03-11
Abstract: Disclosed is an imidazole compound of the Formula I wherein the substituents are disclosed within the specification or a pharmaceutically acceptable salt thereof. Also disclosed is the use of a compound of Formula I in the manufacture of a medicament for inhibiting Abeta-peptide production in a mammal.
Patent NZ-550284-A (NZ)
Title: Multiple promoter expression cassettes for simultaneous delivery of RNAi agents
Inventor: SUHY DAVID A
IPC: C07H21/04
Filed: 2005-03-04
Abstract: The present invention provides multiple-promoter expression cassettes for simultaneous delivery of RNAi, preferably to mammalian cells. The cassettes comprise at least three components which each comprise a promoter, terminator, and an RNAi-encoding sequence which are operably linked. At least one of the RNAi-encoding sequences consists of SEQ ID No. 22. Further disclosed are uses of the genetic construct in the manufacture of a medicament for inhibiting hepatitis C virus from binding to targets expressed in a cell, and modifying the hepatitis C virus nucleic acid targets in a cell.
Patent NZ-552549-A (NZ)
Title: Methods for obtaining paclitaxel from taxus plants
Inventor: GABETTA BRUNO
IPC: C07D305/14
Filed: 2005-06-24
Abstract: Methods for obtaining paclitaxel from plants containing paclitaxel are disclosed. Plant material is first obtained from plants containing paclitaxel. Paclitaxel is then extracted from the plant material. Subsequently, paclitaxel is separated from the paclitaxel extract using a series of column chromatography separation steps to obtain at least one fraction containing paclitaxel. The paclitaxel in a fraction that is obtained from the final chromatography step is crystallized. Using these methods, high purity paclitaxel may be efficiently obtained from plants containing paclitaxel.
Patent NZ-560368-A (NZ)
Title: Methods and compostions for treatment of central and peripheral nervous system disorders and novel compounds useful therefor
Inventor: FISHER ABRAHAM
IPC: A61P17/16
Filed: 2003-05-01
Abstract: Disclosed is a crystalline form of (S)-2-ethyl-8-methyl-1-thia-4,8-diazaspiro[4.5]decane-3-one (AF267B) having the configuration (I). Also disclosed is the use of the crystalline form above and pharmaceutically acceptable salts thereof in the preparation of a pharmaceutical composition for stimulating the M1 muscarinic receptor.
Patent NZ-563043-A (NZ)
Title: Thermophilic microorganisms with inactivated lactate dehydrogenase gene (LDH) for ethanol production
Inventor: ATKINSON ANTHONY
IPC: C12N9/04
Filed: 2006-05-03
Abstract: Provided is a thermophilic microorganism, modified to permit the increased production of ethanol, wherein the modification is the inactivation of the lactate dehydrogenase gene of a wild-type thermophilic microorganism, which can be Geobacillus sp., wherein the native lactate dehydrogenase gene. or a portion thereof, has been deleted. Further provided is a method of producing ethanol by the said microorganism and animal feed comprising the microorganism.
Patent NZ-566313-A (NZ)
Title: Amorphous solid dispersions of 7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4, 5-b]indole-1-acetamide
Inventor: JACOBS IRWIN C
IPC: A61K9/14
Filed: 2006-08-24
Abstract: Disclosed is a solid dispersion comprising substantially amorphous 7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide and a stabilizing polymer; wherein said stabilizing polymer is one or more polymers selected from the group consisting of hydroxypropyl methylcellulose phthalate, cellulose acetate phthalate, hydroxypropyl methyl cellulose acetate succinate, and a polymethacrylate. Also disclosed is the use of the above mentioned solid dispersion in the manufacture of a medicament for the treatment or prevention of a disease or disorder linked to a dysfunction of peripheral-type benzodiazepine receptor, neurodegenerative disease, neuropathy, cancer, tumors, cutaneous stress, rheumatoid arthritis or a cardiac disorder.
Patent NZ-567262-A (NZ)
Title: Cyclosporin derivatives and their use for the treatment and prevention of hepatitis C infection
Inventor: HOUCK DAVID RENWICK
IPC: A61K38/21
Filed: 2006-10-02
Abstract: Disclosed is the use of a therapeutically effective amount of 3-[(R)-2-(N,N-dimethylamino)ethylthio-Sar]-4-(gamma-hydroxymethylleucine )cyclosporin, or a pharmaceutically acceptable salt or solvate thereof, for the preparation of a medicament for treating or preventing hepatitis C virus infection, wherein the medicament is prepared for administration in combination with a therapeutically effective amount of a second agent, or a pharmaceutically acceptable salt or solvate thereof, wherein said second agent is selected from the group consisting of: (a) inhibitors of NS3-4A protease; (b) nucleoside inhibitors of NS5B RNA-dependent RNA polymerase; (c) nonnucleoside inhibitors of NS5B RNA-dependent RNA polymerase; (d) ribavirin; and ( e) immunomodulatory agents.
Patent NZ-568261-A (NZ)
Title: Method and apparatus for applying bar code information to products during production
Inventor: LUBOW ALLEN
IPC: G06K17/00
Filed: 2002-10-25
Abstract: An error detection method for use in a production line in which bar codes are applied to products is provided. The method includes: receiving first check data at a printer computer that controls a printer on the production line; wherein the first check data is calculated at another computer based on information associated, at least in part, with a production run on the production line; receiving the information at the printer computer; computing second check data at the printer computer based on the received information; and determining whether the first and second check data agree. An apparatus for applying this method is also provided.
Patent NZ-578165-A (NZ)
Title: Food compositions incorporating additional long chain fatty acids
Inventor: WILKES RICHARD S
IPC: A23L33/00
Filed: 2008-01-03
Abstract: Disclosed is a food product comprising an oil from a transgenic plant comprising at least 10% by weight stearidonic acid based on the total weight of fatty acids in the oil and a soybean oil comprising less than 3% by weight alpha-linolenic acid based on the total weight of fatty acids in the soybean oil, the food product exhibiting at least 5% longer shelf-life against flavour degradation than an otherwise identical food product having eicosapentaenoic acid rather than stearidonic acid.
Patent NZ-579694-A (NZ)
Title: Magnesium threonate compositions and uses thereof
Inventor: LIU GUOSONG
IPC: A61K31/225
Filed: 2008-03-24
Abstract: The use of magnesium threonate for the treatment of a neurological disorder. The magnesium threonate can be formulated for oral ingestion as a food supplement or foodstuff. The neurological disorder can be dementia, Alzheimer's disease, Parkinson's disease, mild cognitive impairment, attention deficient hyperactivity disorder, synaptic density loss, schizophrenia, a neurological disorder that causes fatigue or neurological disorder caused by hypertension.
Patent NZ-582459-A (NZ)
Title: Antimicrobial peptide, compositions, and methods of use
Inventor: STONE HONGRAN FAN
IPC: A61K38/04
Filed: 2008-07-28
Abstract: Provided is an antimicrobial cationic peptide with the sequence Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-(Lys)15-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg (SEQ ID NO:5). The peptide can be used to inhibit, kill or lyse various gram-negative and gram-positive bacteria, including acne, onychomycosis and dental caries.
Patent NZ-584593-A (NZ)
Title: Automatic feeding machine for filling blister packs
Inventor: KIRBY RAYMOND GEORGE
IPC: B65B5/10
Filed: 2008-09-15
Abstract: Automatic feeding machines are commonly used for filling blister packs with items of product such as pharmaceutical dosage forms. These machines are usually designed for the handling of a specific shape and sized product item. Handling of different shaped items requires expensive re-tooling of all the product item contact components. The disclosure allows a single feeding machine to be quickly configured for use to handling a wide variety of item sizes/shapes. A machine has a tray (36) defining a series of tapered channels (40) and a container (22) slideably mounted above the tray. A wall of the container and the channels together define apertures into each channel through which items of product pass out of the container. Sliding movement of the container across the planar tray surface (38), along and over the channels, allows the size of the apertures to be adjusted depending upon the size of the item of product to be handled, using the same components.
Patent NZ-585390-A (NZ)
Title: A valve assembly having a reinforced valve seat
Inventor: DEVINE DONALD
IPC: F16K27/04
Filed: 2008-11-14
Abstract: A reinforced knife gate valve which maintains its rigidity as the knife gate slides between closed and open positions. The knife gate valve includes a valve body defined by a first body half and a second body half. The valve body defines a flow path, a knife gate channel and a seat channel. The valve includes a knife gate which slides in the knife gate channel. When in an open position the knife gate allows process flow through and prevents process flow when in a closed position. The valve further includes a seat assembly which is positioned within the seat channel. The seat assembly is defined by a horizontal top segment, a pair of vertical segments and a lower segment shaped to correspond to the shape of a lower edge of the knife gate. The seat assembly is compressed and retained between the first and second valve body halves. A reinforcing plate is disposed within the horizontal top segment, such that the horizontal top segment maintains its rigidity when the knife gate slides within the seat assembly.
Patent NZ-585895-A (NZ)
Title: Recombinant newcastle disease virus comprising a transgene encoding a fusion protein comprising a binding domain and a heterologous domain comprising a toxin
Inventor: BEIER RUDOLF
IPC: A61K35/76
Filed: 2005-11-10
Abstract: Disclosed is a recombinant oncolytic paramyxovirus comprising a nucleic acid with at least one transgene, wherein the transgene encodes a binding protein that has a therapeutic activity when expressed by a virus infected tumor cell, and wherein the binding protein is an fusion protein comprising at least binding domain and a geterologous domain containing a toxin.
Patent NZ-593593-A (NZ)
Title: Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
Inventor: WENDT MICHAEL D
IPC: A61K31/635
Filed: 2010-01-15
Abstract: 593593 Disclosed are benzamide compounds with a substituted sulfonyl group on the amide and substituted heteroalkyl group at the 4 position of the benzamide. Examples of these compounds are: 4-[4-(3,3-diphenylprop-2-enyi)piperazin-1-yl]-N-[(3-nitrophenyl)sulfonyl]benzamide; N-[(2-bromophenyl)sulfonyl]-4-(4-{ [2-(4-chlorophenyl)cyclohex-1-en-1-yl]methyl} piperazin-1-yl)benzamide; N-[(3-bromophenyl)sulfonyl]-4-(4-{ [2-(4-chlorophenyl)cyclohex-1-en-1-yl]methyl} piperazin-1-yl)benzamide. The compounds inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein. Also disclosed is a composition comprising one of the compounds and the use of one of the compounds for the manufacture of a medicament for treating bladder cancer, brain cancer, breast cancer, bone marrow cancer, cervical cancer, chronic lymphocytic leukaemia, colorectal cancer, oesophageal cancer, hepatocellular cancer, lymphoblastic leukaemia, follicular lymphoma, a lymphoid malignancy of T-cell or B-cell origin, melanoma, myelogenous leukaemia, myeloma, oral cancer, ovarian cancer, non-small cell lung cancer, prostate cancer, small cell lung cancer or spleen cancer.
Patent NZ-597664-A (NZ)
Title: Humanized anti-cdcp1 antibodies
Inventor: AUER JOHANNES
IPC: C07K16/28
Filed: 2010-08-26
Abstract: Disclosed is an antibody binding to human CDCP1 comprising a variable heavy chain domain and a variable light chain domain as defined in the specification. The disclosed antibody is used in the treatment of cancer.
Patent NZ-600331-A (NZ)
Title: Plaster-based material including an agent capable of trapping formaldehyde
Inventor: SAHAY-TURNER PARKINA
IPC: E04F13/00
Filed: 2010-11-15
Abstract: The present disclosure relates to the use of plaster-based material which includes an agent that scavenges formaldehyde, in particular plasterboard intended for the interior fittings of residential buildings, for reducing the amount of formaldehyde present in the atmosphere inside residential buildings. The scavenging agent is chosen from compounds comprising active methylene(s), sulphites, tannins and their mixtures. Another subject-matter of the disclosure is the said material.