Patent EP-2236505-A1 (EP)
IPC: C07D401/12
Filed: 2009-04-03
Abstract: Aminopyridine or aminopyridazine derivatives (I) and their salts are new. Aminopyridine or aminopyridazine derivatives of formula (I) and their salts are new. R 1>1-6C-alkyl, 2-6C-alkenyl, 2-6C-alkynyl or 3-6C-cycloalkyl (all optionally substituted by halo, CN, nitro, OH, 1-6C-alkyl, 1-6C-alkoxy, 3-6C-cycloalkyl, 1-6C-haloalkoxy, 1-6C-alkylthio, aryl, hetaryl, arylalkyl or hetarylalkyl, where the aryl, hetaryl, arylalkyl or hetarylalkyl is optionally substituted by halo, CN, nitro, OH, 1-6C-alkyl, 2-6C-alkenyl, 2-6C-alkynyl, 3-6C-cycloalkyl, 1-6C-alkoxy, 1-6C-haloalkyl, 1-6C-haloalkoxy or 1-6C-alkylthio), or H; X : CH or N; Q : an aromatic, optionally 1-3 heteroatoms of N, S, O substituted 5-6 membered ring, which is optionally substituted by R 2>-R 4>or A-Y 1>(when X is N), or an aromatic, optionally 1-3 heteroatom of N, S or O substituted 6 membered ring (which is optionally substituted by R 2>-R 4>or A-Y 1>), or an aromatic, optionally 1-3 heteroatoms of N, S or O substituted 5 membered ring (where at most one of the heteroatom is N), which is optionally substituted by R 2>-R 4>or A-Y 1>, 1H-pyrazole group of formula (Q8a), 2H-[1,2,3]triazole group of formula (Q8b), 1H-imidazole group of formula (Q8c) or (Q8d) (when X is CH); W 1>O or S; either R 2>, R 3>amino, 1-6C-alkyl, 1-6C-alkoxy, 1-6C-alkoxy-1-6C-alkyl, 2-6C-alkenyl, 2-6C-alkynyl or 3-6C-cycloalkyl (all optionally substituted by halo, 1-6C-alkyl, 1-6C-alkylcarbonyl, 1-6C-alkoxy, 1-6C-haloalkoxy, 3-6C-cycloalkyl, 3-6C-cycloalkylcarbonyl, CN, nitro, OH, 1-6C-alkylthio, 1-6C-alkylsulfinyl, 1-6C-alkylsulfonyl, (1-6C-alkoxy)carbonyl, 1-6C-alkylamino, 3-6C-cycloalkylamino, (1-6C-alkyl)-3-6C-cycloalkylamino or (het)aryl (optionally substituted by halo, CN, nitro, OH, 1-6C-alkyl, 1-6C-haloalkyl, 2-6C-alkenyl, 2-6C-alkynyl, 3-6C-cycloalkyl, 1-6C-alkoxy, 1-6C-haloalkoxy, 1-6C-alkylthio, 1-6C-alkylsulfinyl, 1-6C-alkylsulfonyl)), H, OH, halo or nitro; or R 2>R 3>a 5-7-membered, 1-3 heteroatom of N, S or O containing, heteroaromatic ring, which is optionally substituted by 1-6C-alkyl; R 4>1-6C-alkyl, 1-6C-alkoxy-1-6C-alkyl, 2-6C-alkenyl, 2-6C-alkynyl, 3-6C-cycloalkyl, aryl or hetaryl (all optionally substituted by halo, 1-6C-alkyl, 1-6C-alkylcarbonyl, 1-6C-alkoxy, 1-6C-haloalkoxy, 3-6C-cycloalkyl, 3-6C-cycloalkylcarbonyl, CN, nitro, OH, 1-6C-alkylthio, 1-6C-alkylsulfinyl, 1-6C-alkylsulfonyl, (1-6C-alkoxy)carbonyl, 1-6C-alkylamino, 3-6C-cycloalkylamino, (1-6C-alkyl)-3-6C-cycloalkylamino, aryl or hetaryl (which is optionally substituted by halo, CN, nitro, OH, 1-6C-alkyl, 1-6C-haloalkyl)), or H; A : a direct bond or 1-6C-alkylene, 1-6C-alkyleneoxy, oxy(1-6C)-alkylene, thio(C1-C6)-alkylene, 1-6C-alkylenethio, -O-, -S-, 1-4C-alkylenecarboxy, carboxy(1-4C)-alkylene, -NR 5>, -C=N-O-, 1-4C-alkylene carbamido, carbamido(1-4C)-alkylene, -NR 5>(C=O)O-, NR 5>(SO 2)-, -NR 5>(C=O)NR 5>- or -(SO 2)-; R 5>1-6C-alkyl, 3-6C-cycloalkyl or H; and Y 1>1-6C-alkyl, 3-6C-cycloalkyl, 5-10 membered, annelated ring containing 0-4 heteroatoms of N, S, O (all optionally substituted by amino, 1-6C-alkyl, 1-6C-alkoxy, 1-6C-alkoxy-1-6C-alkyl, 2-6C-alkenyl, 2-6C-alkynyl, 3-6C-cycloalkyl, aryl, hetaryl, 1-6C-arylalkyl, 1-6C-hetarylalkyl, aryloxy, hetaryloxy, sulfonyl, 1-6C-thioalkyl or 1-6C-carboxyalkyl (all optionally substituted by halo, 1-6C-alkyl, 1-6C-alkylcarbonyl, 1-6C-haloalkyl, 1-6C-alkoxy, 1-6C-haloalkoxy, 3-6C-cycloalkyl, 3-6C-cycloalkylcarbonyl, CN, nitro, 1-6C-alkylthio, 1-6C-alkylsulfinyl, 1-6C-alkylsulfonyl, (1-6C-alkoxy)carbonyl, 2-6C-alkenyl, 2-6C-alkynyl, 1-6C-alkylamino, 3-6C-cycloalkylamino, (1-6C-alkyl)3-6C-cycloalkylamino, di(1-4C)alkylamino), halo, nitro or CN), or H. An independent claim is included for an agrochemical composition comprising (I), diluents and surface active materials. [Image] [Image] ACTIVITY : Insecticide; Arachnicide; Anthelmintic; Nematocide; Protozoacide; Virucide; Herbicide; Plant Growth Regulant; Fungicide; Antibacterial. MECHANISM OF ACTION : None given.