baber/WOPTO huggingface dataset:
Patent CA-2303248-A1 (CA)
Title: 1,3-dihydroxy-20,20-dialkyl-vitamin d3 analogs
Inventor: USKOKOVIC MILAN RADOJE
IPC: A61K31/593
Filed: 1998-09-02
Abstract: This invention relates to 1,3-dihydroxy-20,20-dialkyl-vitamin D3 analogs of Formula (I), compositions comprising the analogs, methods of preparing the analogs and methods of treatment of osteoporosis, secondary hyperparathyroidism, cancer and autoimmune diseases using such analogs.
Patent CA-2304229-A1 (CA)
Inventor: NAKATSUKA KATSUTO
IPC: H01F1/34
Filed: 1998-09-11
Abstract: A magnetic fluid which can work powerfully and at high precision under the action of an external magnetic field, is remarkably increased in the viscosity by applying an external magnetic field and regulating it, can be controlled in the viscosity easily and accurately, is excellent in the oxidation resistance of the particles and the dispersibility thereof, and exhibits satisfactorily large viscosity characteristics; and a process for the production of the same.  The fluid is characterized in that magnetic metal particles covered with antioxidant films are stably dispersed in a solvent and that the stable dispersion is maintained, and the process is characterized by forming oxide films on the surfaces of starting oxide particles for the production of magnetic metal particles, reducing the resulting oxide particles to form magnetic metal particles covered with antioxidant films, and dispersing the magnetic metal particles covered with antioxidant films in a solvent stably.
Patent CA-2304984-A1 (CA)
Inventor: YADAV NARENDRA S
IPC: C12N15/82
Filed: 1998-10-23
Abstract: L'invention concerne un système binaire d'expression virale régulée dans des plantes. Il est composé de deux éléments intégrés dans les chromosomes. Un élément est un proréplicon contenant des séquences virales à action cis nécessaires pour la réplication dont une séquence contient un gène ciblé. L'autre élément est un gène chimère de réplication à action trans comprenant un promoteur relié à la région codante pour la réplication de la protéine virale. Le proréplicon est exempt du gène de réplication essentiel pour la réplication du réplicon et, de ce fait, ne peut pas subir de réplication épisomique autonome. Cependant, l'expression régulée de la protéine de réplication à action trans dans des cellules de la plante contenant également le proréplicon déclenchera la libération d'un réplicon libre depuis le proréplicon intégré, ce qui produira sa réplication épisomique in trans, ainsi que l'expression du gène ciblé, s'il est présent, par l'intermédiaire de l'amplification génique. Ce système d'expression est utile à la fois pour la production de protéines étrangères et la mise en sommeil de gènes endogènes et de transgènes dans le tissu de la plante. L'expression spécifique au tissu est commandée par le choix du promoteur régulant la transcription du gène de réplication à action trans.
Patent CA-2306011-A1 (CA)
Title: A connection collar having an adjustable damper
Inventor: GRINBERGS PETER KARL
IPC: F16K1/22
Filed: 2000-04-18
Abstract: The present invention relates to a connection collar for a duct ventilation system and furnace. The connection collar is comprised of a self guiding and self-locking damper valve, which when positioned becomes part of a completely sealable joint when used with preferably flexible insulated heating pipe. With the adjusting apparatus and locking apparatus completely contained within the connection collar the connection collar forms a vapor barrier when used with the preferable pipe and or furnace. The self-locking aad self guiding apparatus comprises of a spring biassing arrangement and a cone shaped receiver equipped with catch teeth which when engaged mate with teeth circumferentially positioned on the damper apparatus.
Patent CA-2306169-A1 (CA)
Title: System and method for importing images
Inventor: RAJENDRA ANSLEM J
IPC: G06F3/0486
Filed: 2000-04-14
Abstract: During import of images into an existing document, for each selected image, the present invention creates a low resolution thumbnail preview image that is displayed in or with the cursor and moves about the existing document with the cursor according to the movement of the mouse. A crosshair cursor is also displayed, indicating to the user that clicking and dragging will stark the definition of a bounding rectangle of the image when it is actually placed into the existing document.
Patent CA-2306983-A1 (CA)
Title: Methods for treating hypercoagulable states or acquired protein c deficiency
Inventor: HARTMAN DANIEL LAWRENCE
IPC: A61P31/04
Filed: 1998-10-14
Abstract: A method of treatment for human patients with an acquired hypercoagulable state or acquired protein C deficiency associated with sepsis, purpura fulminans, meningococcal sepsis, bone marrow and other transplantations, severe burns, pregnancy, major surgery, severe trauma, or ARDS, which comprises administering activated protein C providing a highly selective therapeutic agent with a low potential for causing bleeding complications.
Patent CA-2307140-A1 (CA)
Title: Dynamic mixer control in plastics and rubber processing
Inventor: EDWARDS DANIEL C
IPC: B29B7/28
Filed: 1998-11-03
Abstract: A simple and efficient process and automated system is provided for controlling the mixing of polymeric material and additive materials in an internal mixer to provide quality products and batch to batch product uniformity. Real time mixing temperature profiles of a plurality of good quality batches of the same product are developed. The profiles are then superimposed or averaged to produce a real time temperature curve with maximum and minimum temperature tolerance limits, thus providing a range of batch temperatures that are allowable in real time during the mixing cycle. A process control system is programmed to store the range of allowable temperatures and I to signal a mixer control to change at least one of the rotor speed and the ram pressure when the real time batch temperature falls outside the reference temperature range for a predetermined period of time.
Patent CA-2307345-A1 (CA)
Inventor: HADDEN JOHN W
IPC: G01N33/50
Filed: 1998-10-16
Abstract: Cette invention se rapporte à un procédé et à un kit servant à déterminer des candidats à une immunothérapie, à surveiller l'effet d'une immunothérapie et à analyser la fonction d'immunité véhiculée par les cellules chez un patient nécessitant une immunothérapie. Ce procédé consiste à réaliser deux tests cutanés d'intradermo-réaction et à lire le test cutané après vingt-quatre heures. L'un de ces tests cutanés consiste à administrer un mitogène, tel que de la phytohémagglutinine (PHA), de la concanavaline A (ConA), un antigène pokeweed (APW) et d'autres mitogènes, selon la pratique connue. Dans le test cutané à la PHA, les réponses reflètent la capacité des lymphocytes T qui sont présents à réagir à la PHA et à libérer des cytokines comme IL-2 et à induire une infiltration de monocytes/macrophages conduisant à une réaction dermique d'hypersensibilité de type retardé, qui est observée dans la caractéristique du test cutané correspondant à la réponse du membre afférent du système immunitaire. Dans le test cutané à NCM (mélange de cytokine naturelle stimulée par mitogènes), les réponses reflètent la capacité des cytokines de lymphocytes T préformées à induire l'accumulation de monocytes/macrophages caractéristique de la réponse du membre efférent.
Patent CA-2309433-A1 (CA)
Title: Method for measuring atm cell rates
Inventor: HEISS HERBERT
IPC: H04L12/56
Filed: 1998-08-14
Abstract: The transmission of ATM cells often requires measuring the frequency of the transmitted ATM cells of a connection. In general, measurements are carried out within a fixed time interval. This is problematic in that this type of measurement does not take into account the type of connection. The invention helps to solve this problem by using the traffic characteristic of the ATM cells as a criterion to determine the moment when a measurement should be carried out.
Patent CA-2318581-A1 (CA)
Title: Force discrimination assay
Inventor: LEE GIL U
IPC: C12Q1/68
Filed: 1999-01-20
Abstract: A sensor for a selected target species has (1) a substrate which has been chemically modified by attachment of substrate modifiers; (2) one or more magnetically active beads which have been chemically modified by attachment of bead modifiers, where these bead modifiers will have a binding affinity for the substrate modifiers in the presence of the target species, and a measurably different binding affinity for the substrate modifiers in the absence of the target species; (3) an adjustable source of a magnetic field for exerting a force on the beads; and (4) an imaging system, for observing and counting beads bound to said substrate. In a preferred embodiment, the invention further has a system for identifying clusters of beads, and for removing the effect of such clusters from measurements of the target analyte. As with other assays, the sensor relies on the ability of certain molecules to bind with specific target (analyte) molecules.  By coating the beads and the substrate with appropriate molecules, the beads will (or will not) bind specifically to the substrate in the presence (or absence) of the target molecule. When a magnetic field is applied to the substrate, the magnetic beads will be pulled away from the substrate. If the beads are specifically bound to the substrate, however, the beads will be retained on the substrate, indicating the presence (or absence) of the target species.
Patent CA-2319588-A1 (CA)
Title: Materials and methods relating to the treatment of conditions involving mast cells basophils and eosinophils
Inventor: WHITBY HELEN
IPC: A61K39/395
Filed: 1999-03-29
Abstract: This application discloses that inositolphosphoglycans (IPGs) can be obtained from basophils, eosinophils and mast cells and that allergen stimulation of these cells results in IPG release. It also shows that IPGs are second messengers for allergic stimulation as the addition of some types of purified IPGs to non-allergen stimulated cells resulted in histamine release or degranulation. Thus, IPG antagonists can be used for the treatment of conditions (especially allergy and asthma) mediated by the release of IPGs from mast cells, basophils or eosinophils. Preferred IPG antagonists include anti-IPG antibodies, inhibitors of the enzyme GPI-PLD and competitive antagonists.
Patent CA-2323926-A1 (CA)
Title: Novel potentially fluorogenic compounds
Inventor: SCHABERT GUNTER
IPC: C12Q1/04
Filed: 1999-02-02
Abstract: Compounds of formula (I) in which R1, R2, R3, R4 and R5 are hydrogen atoms or chromogenic substituents and X is hydroxyl, OR6 wherein R6 is selected from the group consisting of C1-C4 alkyl, or O-Me+ wherein Me+ is a cation derived from an organic or inorganic base; these compounds do not exhibit significant fluorescence but are capable of being cleaved by phosphatidyl-inositol-specific phospholipase C, an enzyme which is indicative of bacterial activity; the umbelliferyl moity resulting from such cleavage is a strong fluorogen thus providing effective test methods for various pathogenic bacteria, such as Listeria, Staphylococcus and Clostridium species. A synthesis method is disclosed. A preferred species of formula (I) compounds is 4-methylumbelliferyl myo-inositol-1-phosphate and the salts thereof with an organic or inorganic base.
Patent CA-2325644-A1 (CA)
Title: Network enhancement by utilizing geolocation information
Inventor: CHIANG TUNG CHING
IPC: H04B7/26
Filed: 2000-11-09
Abstract: Network performance of a wireless network is enhanced by using geolocation information. The network enhancement may be achieved by determining call-dropping zones by the use geolocation information and by improving the signal quality in these call-dropping zones. The network enhancement may also be achieved in the form of increased capacity and reduced interference by utilizing geolocation information in beam steering and shaping of intelligent antennas. Rather than having antennas passively steering and shaping their beams in terms of the rays coming directly from mobiles or reflected by objects, geolocation information may be used to steer the beams (i.e., when antennas are adaptive) or select particular beams (i.e., when antennas are fixed-beam). In addition, the network enhancement may be achieved by using geolocation information in downtilt technology. The network enhancement may be further achieved by using geolocation information to reduce mobile registration requirements. The network enhancement may be also achieved by better managing the power level of a mobile. Additionally, the network enhancement may be achieved by enhancing load-balancing capabilities in a wireless system by the use of geolocation information.
Patent CA-2326107-A1 (CA)
Title: Miniaturized microtiter plate for high throughput screening
Inventor: VOLLERT HENNING
IPC: B01L3/00
Filed: 1999-03-17
Abstract: The invention relates to a miniaturized microtiter plate which has a body made of plas-tic and a base made of glass, 1000 to 4000 vessels (wells) (3), and a cover (4) which prevents evaporation. The diameter of the vessels (wells) (d) is approx-imately 1.0 to 1.8 mm. The base of the microtiter plate (2) has a layer thickness ranging from 0.07 to 0.2 mm and the distance of the outermost vessels (wells) from the edge of the glass base ranges from 4 to 11 mm.
Patent CA-2327014-A1 (CA)
Title: Method and apparatus for providing selectable output voltages
Inventor: OWEN DONALD W
IPC: H01F29/04
Filed: 2000-11-22
Abstract: A transformer is provided along with a combination of bridging tap-changers to provide a wide range of selectable output voltages in discrete, relatively small voltage steps wherein the highest voltage is more than double the lowest output voltage. Relatively inexpensive off-the-shelf, bridging tap-changers are utilized in conjunction with transformer winding schemes to provide a low winding loss ratio.
Patent CA-2327280-A1 (CA)
Title: Modular stairway and balcony railing system
Inventor: ROSS NANCY A
IPC: E04F11/18
Filed: 1999-04-06
Abstract: A modular railing system (121) for stairways and balconies that are straight, curved or of substantially different slopes, includes a selected number of balusters, each having a stanchion (42) for connection to a base support (126) and a handrail member of the balcony or stairway railing system and a barrier part (40) connected to the stanchion. The barrier parts may comprise predetermined ornamental scroll-shaped portions connected to the stanchions at spaced apart points between opposite distal ends of the stanchions and projecting laterally from the stanchions. Alternatively, the stanchions may project from opposite ends of the barrier part. The barrier parts of each baluster may also have a predetermined radius of curvature out of a vertical plane for use in conjunction with curved stairways or balconies. Each baluster has a predetermined ornamental and functional shape to provide a repeating pattern of the railing system throughout its extend and to provide a maximum pass-through dimension to comply with regulatory requirements.
Patent CA-2327943-A1 (CA)
Inventor: TWAROG EDWARD J
IPC: G06F21/72
Filed: 2000-12-08
Abstract: System and method for performing cryptographic operations include providing at least one processor for performing cryptographic operations, memory coupled to the processor for use in performing the cryptographic operations; and a storage component coupled to the processor for storing and retrieving information calculated and used in the cryptographic operations. The processor, memory and storage component are securely enclosed whereby direct access to the cryptographic operations is prevented.    At least the processor is comprised in an integrated circuit. A first power source, which is external to the secure enclosure, is coupled to and supplies power to the processor, the memory and the storage component. A second power source, which is within the housing of the integrated circuit, is coupled to and supplies power to at least the processor. A switch is included for switching from the first power source to the second power source when the cryptographic operations are being performed and for switching from the second power source to the first power source when non-cryptographic operations are being performed.
Patent CA-2330702-A1 (CA)
Inventor: DEVLIN SEAMUS MICHAEL
IPC: E04F15/14
Filed: 1999-04-13
Abstract: The joint thereshown has two stainless steel side plates (21, 22) which are rolled from a single strip and are bent double at the bottom of the lower limb (23) of the Y. The plates have rolled in ridges (24) at the top of this limb (23) and diverge above the ridges (24) as upper Y limbs (26). Between the limbs (26) a core is captivated at a relatively hard, necked lower core-portion or rib (31) by the ridges (24). Above these, a relatively softer upper core-portion or strip (32) fills the space between the upper limbs (26), tapering out with them. The core is a co-extrusion of the two portions (31, 32) joined by a neck (33). It is held in place by the ridges (24) being rolled around lower portion (31). This joint is fitted between tiles at a gap of the width of the ridges (24), by driving it between the tiles to compress the divergent upper Y limbs (26).
Patent CA-2331193-A1 (CA)
Title: Atm connection band control method and control system
Inventor: UKON SHINICHI
IPC: H04L47/80
Filed: 2001-01-17
Abstract: An asynchronous transfer mode connection band control system in a system for transmitting and receiving an asynchronous transfer mode cell utilizing an asynchronous transfer mode network, has data storage means for storing a connection band of a preferential switched virtual connection having high preference in the asynchronous transfer mode network being stored preliminarily as a band acquiring data and storing acquired band data of a switched virtual connection currently established connection, and connection band control means for performing control of connection band on the basis of a total number of bands derived by a sum of the band acquiring data and the acquired band data stored in the data storage means.
Patent CA-2331239-A1 (CA)
Inventor: VANDLEN RICHARD L
IPC: C12N1/21
Filed: 1992-05-21
Abstract: A novel polypeptide with binding affinity for the p185HER2 receptor, designated heregulin-.alpha., has been identified and purified from cultured human cells.  DNA sequences encoding additional heregulin polypeptides, designated heregulin-.alpha., heregulin-.beta.1, heregulin-.beta.2, heregulin-.beta.2-like, and heregulin-.beta.3, have been isolated, sequenced and expressed. Provided herein are nucleic acid sequences encoding the amino acid sequences of heregulins useful in the production of heregulins by recombinant means. Further provided are the amino acid sequences of heregulins and purification methods therefor. Heregulins and their antibodies are useful as therapeutic agents and in diagnostic methods.
Patent CA-2333303-A1 (CA)
Title: Procedes ameliores pour un stockage de cellules neuronales
Inventor: DINSMORE JONATHAN
IPC: A61K35/12
Filed: 1999-07-01
Abstract: L'invention concerne des procédés améliorés qui permettent de stocker des cellules neuronales, de préférence des cellules neuronales dissociées, avant leur utilisation aux fins de transplantation. L'invention concerne également des cellules résultant de la mise en oeuvre desdits procédés. Selon une variante, les procédés décrits consistent à stocker les cellules neuronales dans un milieu sans tampon ajouté ni protéine ajoutée et, selon d'autres variantes, les cellules neuronales sont maintenues à une température de 4· C avant la cryoconservation, ayant par ailleurs une viabilité et/ou une fonctionnalité que l'on peut comparer à la viabilité et/ou à la fonctionnalité de cellules fraîchement recueillies. L'invention concerne en outre des procédés relatifs au stockage et/ou à la transplantation de cellules neuronales porcines.
Patent CA-2333746-A1 (CA)
Title: Resin composition for electrostatic coating
Inventor: AOKI HIROMICHI
IPC: C09D177/00
Filed: 1998-06-12
Abstract: A resin composition for electrostatic coating, comprising a rubber-reinforced aromatic vinyl resin (A), a polyamide elastomer (B), a modified vinyl polymer (C) containing at least one functional group selected from among carboxyl, epoxy, amino and amido, and an alkali metal salt (D); a formed resin article excellent in electrostatic coatability which is formed from the resin composition; and a formed resin article having electrostatic coating film which is produced by coating the articles electrostatically.
Patent CA-2334739-A1 (CA)
Title: Automatic door latch
Inventor: GALVIN DONNA
IPC: E05B63/20
Filed: 1999-06-01
Abstract: An automatic door latch is disclosed. In a preferred embodiment, the latch includes a dead bolt which is automatically moved from a partially retracted or trigger position to a fully extended locking position when a door in which the lock is mounted is closed. When a key is used to unlock the dead bolt from outside of the door, or a finger turn or key is used to unlock the dead bolt from inside of the door, the dead bolt is automatically reset to the trigger position.  In a preferred embodiment, the dead bolt lock includes a multi-position switch mounted in the lock housing which engages a contact member mounted on the dead bolt.   Retraction of the dead bolt into the housing causes the multi-position switch to engage the contact member and to secure the dead bolt in the trigger position. Subsequent retraction of the dead bolt into the housing causes the multi-position switch to disengage from the contact member, thereby allowing the dead bolt to extend from the housing to the locked position. In a preferred embodiment, a latch restraint assembly is provided which holds the dead bolt in the fully retracted position until the restraint assembly is manually released. The automatic door latch comprises relatively few component parts in comparison with conventional locks, and is preferably compatible with standard predrilled door cut-outs.
Patent CA-2340982-A1 (CA)
Inventor: FISH LAURENCE
IPC: H04N21/00
Filed: 1995-09-06
Abstract: A system and methodology for automatically organizing, managing, and distributing digital multi-media information without the negative artifacts which are normally introduced when electronically distributing digitally compressed data and information which contains still images, moving images and sound. Object descriptor fields define the actual multi-media object and its relative mixture of digitized audio, video, text and picture content. Multi-media information packets and segments descriptors are transmitted over available transmission system architectures.
Patent CA-2341122-A1 (CA)
Title: A device for detecting derailment of trains
Inventor: NICO ADILSON ROBERTO
IPC: B60T17/18
Filed: 2001-03-16
Abstract: "A DEVICE FOR DETECTING DERAILMENT OF TRAINS, to~ be attached to the car, that acts promptly in the event of derailment, fully or emergently actuating the brake system of the train; said operating device being provided only with mechanical and pneumatic signals, not requiring electric and/or radio signals. The device is comprised of a general piping (20) connected to a so-called fuse element (10), through a tubing (11); the fuse (10) being defined by a blind flange that in principle blocks the air flow; a puncture (12) being provided in the interior of said fuse, and its body being machined in such a way that a suitable region (4) for the occurrence of a disruption and the consequent fast relief of the air present in the general plumbing (20) is created.