baber/WOPTO huggingface dataset:
Patent CA-2362845-A1 (CA)
Title: Forme cristalline d'eplerenone
Inventor: LITTLE CLAY R
IPC: A61P1/16
Filed: 2000-12-04
Abstract: La présente invention concerne une nouvelle forme cristalline (Form L) de l'éplérénone pharmaceutique antagoniste du récepteur de l'aldostérone, présentant une stabilité physique relativement élevée à des températures normales de stockage et d'utilisation. Cette invention concerne également des compositions pharmaceutiques comprenant de l'éplérénone Form L, éventuellement accompagnée d'une ou de plusieurs formes solides d'éplérénone, en une quantité de dosages unitaires totale d'éplérénone allant d'environ 10 à environ 1000 mg, et comprenant également un ou plusieurs excipients acceptables du point de vue pharmaceutique. L'invention a également pour objet des procédés permettant de préparer de l'éplérénone Form L et des compositions comprenant de l'éplérénone Form L, et un procédé de prévention et/ou de traitement d'un état pathologique ou un trouble médié par l'aldostérone, comprenant l'administration à un sujet d'une quantité efficace du point de vue thérapeutique d'éplérénone, au moins une partie de l'éplérénone présente étant de l'éplérénone Form L.
Patent CA-2363414-A1 (CA)
Inventor: SCHULTZ GARY A
IPC: G01N30/72
Filed: 2000-02-29
Abstract: A droplet/electrospray device and a liquid chromatography-electrospray system are disclosed. The droplet/electrospray device (100) comprises a substrate (102) defining a channel (104) between an entrance orifice (106) on an injection surface (108) and an exit orifice on an ejection surface (112), a nozzle (110) defined by a portion recessed from the ejection surface (112) surrounding the exit orifice, and an electrode (122) for application of an electric potential to the substrate (102) to optimize and generate droplets or an electrospray (62). A plurality of these electrospray devices (100) can be used in the fonn of an array of miniaturized nozzles. The liquid chromatography-electrospray device (160) comprises a separation substrate (162) defining an introduction channel (164) between an entrance orifice and a reservoir (166) and a separation channel (168) between the reservoir (166) and an exit orifice (170), the separation channel (168) being populated with separation posts (174) perpendicular to the fluid flow.
Patent CA-2364173-A1 (CA)
Title: A novel agropolymer used for purification of polluted water or contaminated water containing metal or ions and a method of producing the agropolymer
Inventor: PRASAD YANDAPALLI DURGA
IPC: C02F/
Filed: 2000-02-24
Abstract: The invention relates to a novel agropolymer comprising carbohydrate and/or silica matrix substantially devoid of at least proteins, tannins and polyphenols and having metal binding reactive sites, a method of producing said novel agropolymers from plant material such as seed coats, husks or hulls of the various agricultural crops (Oryza sativa, Panicum miliaceum, Setaria italica, Cajanus cajan, Vigna mungo, Vigna radiata, Triticum sp., Ricinus communis, Helianthus annus, Gossypium sp.  Arachis sp.), and a method of purifying of metal and ion polluted/contaminated aqueous solutions including metal or ion polluted drinking water or ground water using the said agropolymer.
Patent CA-2366490-A1 (CA)
Title: Reflectively coated optical waveguide and fluidics cell integration
Inventor: ROWE CHRIS A
IPC: G01N33/543
Filed: 2000-03-22
Abstract: A multimode waveguide device for assays includes a multimode waveguide (12) with a patterned, reflective surface coating (22). The exposed portion of the reflectively coated waveguide surface are for analyte recognition. A fluidics cell (10) is attached to the waveguide so that the channel or channels (30) of the fluidics cell (10) match with the exposed portion or portions of the waveguide surface. The channel or channels (30) direct one or more sample fluids over the exposed portion or portions of the waveguide surface. The reflective coating minimizes loss and scattering of excitation and fluorescence light during a fluorescence assay.
Patent CA-2368049-A1 (CA)
Title: Integrin receptor ligands
Inventor: HORNBERGER WILFRIED
IPC: C07D401/04
Filed: 2000-03-29
Abstract: The invention relates to novel compounds that bind to integrin receptor ligands. The invention also relates to the production thereof, to their use as integrin receptor ligands and to their use for treating diseases, to pharmaceutical preparations that contain said compounds and to pharmaceutica l preparations that contain at least one additional active compound.
Patent CA-2368135-A1 (CA)
Title: Xylo-lna analogues
Inventor: WENGEL JESPER
IPC: A61K48/00
Filed: 2000-03-17
Abstract: A bicyclic nucleoside derivative, wherein an intranucleoside ring locks the ring conformation of the nucleoside, is termed an LNA - a Locked Nucleic Acid. LNAs of the xylo-configuration, considered usefu l as therapeutic agents, diagnostic agents and useful for the formation of oligonucleotides, have been prepared. These oligonucleotides are also useful  as a therapeutic and in diagnostic fields. Furthermore, oligonucleotides comprising LNAs of the xylo-configuration are useful for high-affinity targeting of complementary single stranded and double stranded DNA and RNA a nd have interesting activity with regards to specificity and affinity to oligonucleotides.
Patent CA-2368297-A1 (CA)
Title: Multi-application wood working knife and clamping assembly
Inventor: BILLER SVEN-OLOV
IPC: B27G13/04
Filed: 2002-01-17
Abstract: A wood working knife for use in a wood working machine, comprising a knife body having a first cutting edge and an opposed second cutting edge, the knife body having a first clamping surface and a second clamping surface. The first clamping surface has opposed clamping features separated by a middle section, the opposed clamping features and the middle section being sized and shaped such that, upon the knife body being inserted into a clamping assembly, the clamping forces are localized towards the opposed cutting edges and away from the middle section.
Patent CA-2368570-A1 (CA)
Inventor: LEES ROBERT HARPER
IPC: G08G1/042
Filed: 2000-03-30
Abstract: Loop sensing apparatus for detecting vehicles travelling along a lane of a roadway comprises an outer loop producing a region of magnetic field with the same polarity and an inner loop sized to fit within this region of constant polarity. The inner loop provides two regions of opposite polarity, so that field produced by the outer loop has a null effect on the inner loop. Detection circuitry energises both the outer and inner loops individually for separate detection of vehicles passing over the loops.
Patent CA-2371914-A1 (CA)
Inventor: WU BENJAMIN M
IPC: A61K6/838
Filed: 2000-05-18
Abstract: Customized implants for use in reconstructive bone surgeries where anatomica l accuracy and bone adaptation are important, such as plastic and craniomaxillofacial reconstructions. This implant comprises a porous surface  layer and a tough inner core of interpenetrating phase composite. The porous  surface layer enhances the biocompatibility, tissue ingrowth, and implant stability. The tough inner core improves the mechanical properties of the implant with a high fracture toughness and a low modulus. The anatomical accuracy of the implants will minimize the intra-operative manipulation required to maintain a stable host bone-implant interface.
Patent CA-2373286-A1 (CA)
Title: Process for large scale preparation of sphingosines and ceramides
Inventor: ROCHLIN ELIMELECH
IPC: C07H15/10
Filed: 2000-05-09
Abstract: Synthetic methods for convenient large scale preparation of D-erythro sphingosines and ceramides of high isomeric purity are described.
Patent CA-2374309-A1 (CA)
Inventor: BROOKER BRIAN EDWARD
IPC: A23L9/20
Filed: 2002-03-04
Abstract: A method of forming a food product which contains an emulsion, the method comprising contacting a spray of the product in liquid form with a cryogen so as to cool the liquid product and effect a rapid conversion of the liquid product to a solid.
Patent CA-2376846-A1 (CA)
Title: High-voltage bushing
Inventor: CHRISTEN THOMAS
IPC: H02G15/06
Filed: 2000-06-13
Abstract: Said lead-through has a current conductor (1) to which high voltage can be fed. A section of the current conductor (1) is surrounded by a varistor arra y (9). The lead-through also contains two supply terminals (4, 6), one (6) of which can be connected to high voltage and the other (4) is connected to ground, a lead-through insulator (5) provided between the current conductor (1) and the varistor array, in addition to a clamping device (11) that exert s a contact force on the supply terminals (4, 6) and the varistor array (9) placed in the form of a sandwich between the latter. The clamping device has  an insulating part that exerts a contact force on both supply terminals. The  lead-through insulator is embodied in the form of a shaped body and has a support element provided with a guide surface for a contact (1a) of a plug- type connector that is connected to a current conductor (1) with a cable or a lead-through of an electrical device.
Patent CA-2376920-A1 (CA)
Title: Method for preventing tumoral growth
Inventor: SEITZ CAROLA
IPC: A61K48/00
Filed: 2000-06-21
Abstract: A method for preventing inflammations, auto-immune diseases and tumoral growth, whereby LTBR-mediated activation is suppressed.
Patent CA-2377356-A1 (CA)
Inventor: GOIRAN THIERRY
IPC: B60P1/64
Filed: 2002-03-19
Abstract: L'appareil est prevu pour permettre a un véhicule (1) de poser ou de prendre au sol une charge (5) telle qu'une benne ainsi que de vider cette charge, qui est munie, sur une face avant, d'une anse de levage (6), ledit appareil comportant un bras de manutention (11) déformable et basculant admettant, outre une position de transport et une position de pose ou de prise au sol, une position de vidage à laquelle parvient un crochet (20) prévu pour s'engager avec l'anse de levage (6), en pivotant, sous l'effet d'un verin de basculement (12), autour d'un axe transversal de pivotement (21) situe a l'arriere de l'appareil, les moyens d'articulation autour de cet axe etant liberables et un verin (15) etant prevu pour relever une biellette (23) appartenant au bras de manutention (11) en la faisant pivoter vers le haut et vers l'avant.      Le procede vise la mise sur pied dune charge (5) qui est alors plus haute que lorsqu'elle est positionnee sur l'appareil.
Patent CA-2379706-A1 (CA)
Inventor: GUTIERREZ BERNARDO A
IPC: H01M8/04
Filed: 2000-07-14
Abstract: A novel fuel particle feeding mechanism that significantly improves operation of a refuelable electrochemical power source is provided. One embodiment of the mechanism provides an input of electrolyte and electrochemically active particles into one or more electrochemical cells through a feed tube. The feed tube has several embodiments that improve the flow of electrolyte and particles, and the even and complete settling of particles into individual cell cavities. Each cell cavity is completely filled, evenly and without clogging when open, and fluid communication between cell cavities is completely cut off when closed, to prevent short-circuiting of the power source during discharge or standby. Means are provided to prevent clogging of the feed tube with fuel particles, to promote complete filling of the cell cavities with fuel, and to prevent fuel particles from prematurely flowing out of the cell cavities. A method of operation is also described.
Patent CA-2380265-A1 (CA)
Inventor: RICCO MARIO
IPC: F02M37/10
Filed: 2002-04-04
Abstract: In a tank for a system for injection supply of LPG for internal-combustion engines, a number of hydraulic-connection elements associated to a service flange (3) which closes the top opening of the tank are mounted on said flange by fixing to the bottom surface of the latter, without having any parts that are mounted via through holes of the flange. Provided inside the tank is an electrically operated pump (11) which is fixed to the bottom wall of the tank structure and which in turn carries the structure of a level-sensing device of a capacitive type.
Patent CA-2381743-A1 (CA)
Inventor: NUN EDWIN
IPC: C08J7/02
Filed: 2002-04-10
Abstract: Disclosed is a process for producing objects having self-cleaning surfaces based on polymer surfaces to which particles have been secured. The polymer surfaces used here are treated with a solvent which comprises the particles. This treatment solvates the polymer surfaces while the particles, which are not solvated, deposit on the solvated polymer surface. Removal/evaporation of the solvent secures at least some part of the particles, since the polymer surface hardens again once the solvent has been removed, and some of the particles remain in the polymer surface. Using the process of the invention it is possible to give a self-cleaning surface to any object which can be provided with a polymer surface.
Patent CA-2383902-A1 (CA)
Title: Paintball loader with vibrating mechanism to prevent jamming
Inventor: PERRONE ALDO
IPC: F41B11/80
Filed: 2002-04-29
Abstract: A bulk loader for supplying paintballs to a paintball gun includes a loader housing for internally storing a quantity of paintballs, this housing having a bottom outlet through which paintballs can sequentially drop. A feed tube is connected to this housing at the outlet and extends downwardly therefrom. A paintball moving device which can take the form of a vibrator housing, is mounted in the loader housing and is capable of vibrating in order to move paintballs located near the bottom outlet. A vibrator, which can include a small electrical motor, causes the moving device to vibrate when a paintball jam must be freed up. Preferably the vibrator is mounted in the housing forming the moving device. A control mechanism controls the operation of the vibrator and includes a switch mounted in or adjacent to the feed tube for sensing the absence of a paintball within the feed tube. The vibrator can include a vibration causing weight that is mounted on the output shaft of the motor. The preferred switch comprises a magnetic switch.
Patent CA-2384539-A1 (CA)
Inventor: CRUME GREGG W
IPC: B01D71/32
Filed: 2000-09-11
Abstract: L'invention se rapporte à un élément filtrant présentant une amélioration de ses caractéristiques structurales et de sa résistance à la corrosion et à la chaleur. Cet élément peut servir au filtrage de matières contenant des solides et à la production d'un gâteau de filtration de matières solides sur au moins une de ses surfaces externes. Conformément à l'invention, au moins une partie (24, 26, 28, 38) de la surface externe de l'élément filtrant, distincte de la surface externe (22) destinée à la formation du gâteau de filtre, comporte un moins une matière à base d'un polymère résistant à la chaleur et à la corrosion.
Patent CA-2390116-A1 (CA)
Title: Triphenylalkene derivatives and their use as selective estrogen receptor modulators
Inventor: VAANANEN KALERVO
IPC: C07C43/225
Filed: 2000-11-01
Abstract: The invention provides novel selective estrogen receptor modulator compounds of general formula (I), wherein R1 and R2, which are the same or different are a) H, halogen, OCH3, OH; or b) (II), where X is O, NH or S; and n is an integer from 1 to 4; and R4 and R5, which are the same or different, are a 1 to 4 carbon alkyl, H, -CH2C .ident. CH or -CH2CH2OH; or R4 and R5 form an N-containing five- or six-membered ring or heteroaromatic ring; or c) -Y-(CH2)n CH2-O-R6, where Y is O, NH or S and n is an integer from 1 to 4; and R6 is H, -CH2CH2OH, or -CH2CH2Cl; or d) 2,3-dihydroxypropoxy, 2-methylsulfamylethoxy, 2-chloroethoxy, 1-ethyl-2-hydroxyethoxy, 2,2-diethyl-2-hydroxyethoxy or carboxymethoxy; and R3 is H, halogen, OH or -OCH3; and their non-toxic pharmaceutically acceptable salts and esters and mixtures thereof, which compounds exhibit valuable pharmacological properties.
Patent CA-2392839-A1 (CA)
Title: Bleaching composition
Inventor: KEVELAM JAN
IPC: D06L3/02
Filed: 2000-12-14
Abstract: A bleaching composition is provided for effective bleaching with a bleach catalyst at low temperatures. The bleaching composition comprises of a) from 0.05 microM to 50 mM of an organic substance which forms a complex with a transition metal; b) a source of active oxygen corresponding to 0.05 to 100 mM  of active oxygen; and c) an effective amount of liquid carbon dioxide.
Patent CA-2395221-A1 (CA)
Title: Impression jig assembly for use with dental implants
Inventor: SETHI ASHOK
IPC: A61C8/00
Filed: 2000-12-15
Abstract: The present invention relates to an impression jig assembly for coupling to a bone implant (10) comprising: a split sleeve having co-axial upper and lower sleeve members (31, 32); and a fixing screw (5) for clamping the split sleeve to the implant. The fixing screw in use passes through the split sleeve, and can be withdrawn once impression material has hardened around the assembly to allow the upper sleeve member to separate from the lower sleeve member.
Patent CA-2395231-A1 (CA)
Title: Hydrogel-driven layered drug dosage form
Inventor: THOMBRE AVINASH GOVIND
IPC: A61K9/22
Filed: 2000-12-13
Abstract: A controlled release dosage form for sertraline has a core comprising a sertraline-containing composition and a water-swellable composition wherein the water-swellable composition is in a separate region within the core. A coating around the core is water-permeable, water-insoluble, and has at least one delivery port therethrough. In one embodiment, the dosage form releases sertraline to the use environment at an average rate of 6 to 10 wt.%  per hour from the second to the twentieth hour after introduction to a use environment and less than about 25 wt.% for the first two hours and at least 70 wt.% by the twelfth hour, where the percentages correspond to the mass of drug released from the tablet divided by the total mass of drug originally present in the tablet. In another embodiment, the dosage form releases less than about 25 wt.% of sertraline to the use environment by the second hour after introduction of the dosage form to the use environment, and delivers at least 25 wt.% from the eighth to the twenty-fourth hour.
Patent CA-2396381-A1 (CA)
Inventor: HORII IKUO
IPC: A61K9/12
Filed: 2001-01-09
Abstract: The present invention relates to a nasally administrable composition of a physiologically active cyclic peptide and pharmaceutically acceptable salts thereof that is prepared by homogeneously dispersing a physiologically active cyclic peptide such as antifungal cyclic peptides (aerothricings, echinocandin analogs, pneumocandin analgos, and auroebacidines), antibacterial cyclic peptides (e.g. vancomycin, daptomycin), cyclosporin A, lanreotide, vapreotide, vasopressin antagonist (US 5,095,003) and eptifibatide in unique carrier, i.e.  a physiologically acceptable powdery or crystalline carrier containing a water insoluble polyvalence metal carrier, or organic carrier having a mean particle size of 20 to 500 µm, in the presence or absence of an absorption enhancer and by homogeneously adsorbing onto the carrier, and its use for therapeutic treatment of disease such as systemic fungal infections by intranasal administration. The composition can be nasally administered in powder form.
Patent CA-2398425-A1 (CA)
Title: Process for inhibiting metallic corrosion in aqueous systems
Inventor: HANN WILLIAM M
IPC: C08F22/40
Filed: 2002-08-20
Abstract: The use of a new class of polymeric corrosion inhibiting compositions incorporating pendant heterocyclic groups is disclosed. The polymers form a protective barrier on metallic components to aqueous systems and remain substantive on metallic surfaces over a wide pH range. Moreover, the polymers are resistant to oxidizing biocides, and are substantially impervious to repeated or prolonged exposure to corrosive agents.
Patent CA-2400678-A1 (CA)
Title: Reinforced end and side panel container
Inventor: HOLLAND CRAIG
IPC: B65D5/02
Filed: 2000-10-06
Abstract: A container formed from corrugated board or similar packaging materials, including a base panel (1), a top panel (2), side panels (3 and 4) and end panels (5 and 6) which together form a closed container, said side panels having extension portions (7 and 8) which are folded and secured to form double thickness end flaps which are foldable inside the end panels, the extension portions (7, 8) of at least one end of the side panels having a further portion (13, 14) which is secured to reinforce each side panel
Patent CA-2402398-A1 (CA)
Inventor: IKEDA HARUO
IPC: C12N15/53
Filed: 2001-02-23
Abstract: 22,23-Dihydroavermectin B1a, which is useful in drugs, veterinary drugs and pesticides, can be produced by direct fermentation. Thus, the troublesome an d difficult industrial steps of purifying avermectin B1a and chemically modifying avermectin B1a involved in the conventional are can be omitted and  therefore 22,23-dihydroavermectin B1a can be industrially produced while largely saving the cost and time. Moreover, a preparation containing 22,23- dihydroavermectin B1a alone, which is highly efficacious as a drug, can be produced.
Patent CA-2402920-A1 (CA)
Title: Method for producing coatings, adhesive coatings and seals that can be cured using actinic radiation
Inventor: WIESING REINHARD
IPC: C09D4/06
Filed: 2001-03-13
Abstract: The invention relates to a method for producing coatings, adhesive coatings and/or seals from coating materials, adhesives and/or sealants that can be cured using actinic radiation, on or in primed and unprimed substrates.  According to said method, the coating materials, adhesives and/or sealants are applied to and/or induced in the substrates and the resultant layers are subsequently cured using actinic radiation. Said method uses coating materials, adhesives and sealants which are devoid of photoinitiators and which contain or consist of the following as components that can be activated by actinic radiation: A) at least one (meth)acrylate copolymer which contains as the statistical mean per molecule at least one group (a) comprising at least one bond that can be activated by actinic radiation, whereby group (a) is linked to the basic structure of the (meth)acrylate copolymer (A) by reactions similar to those of polymers, or alternatively B) at least one compound which contains as the statistical mean per molecule at least one group (a) comprising at least one bond that can be activated by actinic radiation and C) at least one (meth)acrylate copolymer which is devoid of groups of type (a). Said coating materials, adhesives and sealants have a concentration of groups that can be activated by actinic radiation of between 70 and 400 mequ./100g solids.
Patent CA-2404546-A1 (CA)
Title: Mixer for preparing feedstuffs
Inventor: PECIS EGIDIO
IPC: A01K5/00
Filed: 2002-09-20
Abstract: A mixer (1) for preparing feedstuffs and mixing pre-shredded forage with various feedstuffs and seed products for animal feeding, comprising a container body (2) which internally accommodates a cylindrical helical (10) feeder rotatably supported by the heads of the container body (2) for the advancement of the products to be mixed. A recirculation scroll (20) is provided inside the region delimited by the feeder (10) and is suitable to impart to the products to be mixed a movement in the opposite direction with respect to the feeder (10).     A tubular element (30) is further provided for containing at least a central portion of the recirculation scroll (20).