Patent EA-001429-B1 (EA)
Title: Antimicrobal composition for mouthwash (its variants)
Inventor: PAN PAULINE
IPC: A61P31/00
Filed: 1996-10-10
Abstract: 1. An antimicrobial composition comprising (a) an antimicrobially effective amount of thymol, eucalyptol, menthol, ethanol, buffer system, comprising sodium benzoate and benzoic acid, an alcohol having 3 to 6 carbon atoms and a vehicle, characterized in that further comprises methylsalicynate and a blockpolymer poly(oxyethelene)-poly(oxypropelene), wherein the components are taken in the following amounts: thymol - in an amount from about 0.0001% to about 0.35% v /v, eucalyptol - in an amount from about 0.001% to about 0.20% v/v, menthol - in an amount from about 0.001% to about 0.3% v/v, ethanol - in an amount from about 20 to about 25% v/v said buffer system for setting pH from about 3,5 to about 9.0 - in an amount from about 0.01 to about 4% v/v, alcohol having 3 to 6 carbon atoms - in an amount from about 0.01 to about 10% v/v, methylsalicynate - in an amount from about 0.001 to about 0.3% v/v, said blockpolymer - in an amount from about 0.01 to about 0.8% v/v,  vehicle remaining   2. The antimicrobal composition of claim 1, wherein comprises alcohol having 3 to 6 carbon atoms in an amount from about 0.2 to about 8.0% v/v. 3. The antimicrobal composition of claim 1, wherein comprises alcohol having 3 to 6 carbon atoms in an amount from about 0.25 to about 1.0% v/v. 4. The antimicrobal composition of claim 1, wherein comprises iso-propanol as an alcohol having 3 to 6 carbon atoms. 5. The antimicrobal composition of claim 1, wherein comprises said block-copolymer in an amount from about 0.001% to about 1.0% v/v. 6. The antimicrobal composition of claim 1, wherein comprises ethanol in an amount from about 20 to about 22.7% v/v. 7. The antimicrobal composition of claim 1, wherein comprises thymol in an amount from about 0.04 to about 0.07% v/v. 8. The antimicrobal composition of claim 1, wherein comprises eucalyptol in an amount from about 0.085 to about 0.10% v/v. 9. The antimicrobal composition of claim 1, wherein comprises menthol in an amount from about 0.0355 to about 0.05% v/v. 10. The antimicrobal composition of claim 1, wherein comprises methylsalicynate in an amount from about 0.04 to about 0.07% v/v. 11. An antimicrobial composition comprising an antimicrobially effective amount of thymol, eucalyptol, menthol, ethanol, buffer system, comprising sodium benzoate and benzoic acid, an alcohol having 3 to 6 carbon atoms and a vehicle, characterized in that further comprises methylsalicynate and a blockpolymer poly(oxyethelene)-poly(oxypropelene), wherein the components are taken in the following amounts: thymol - in an amount from about 0.04% to about 0.07% v /v, eucalyptol - in an amount from about 0.085% to about 0.1% v/v, menthol - in an amount from about 0.035% to about 0.05% v/v, ethanol - in an amount from about 20 to about 22.7% v/v said buffer system for setting pH from about 3.5 to about 9.0 - in an amount from about 0.01 to about 4% v/v, alcohol having 3 to 6 carbon atoms - in an amount from about 0.01 to about 10% v/v, methylsalicynate - in an amount from about 0.04 to about 0.07% v/v, said blockpolymer - in an amount from about 0.01 to about 0.8% v/v,  vehicle - remaining.