baber/WOPTO huggingface dataset:
Patent WO-2020247825-A1 (WO)
Inventor: GOMPERTS STEPHEN
IPC: A61K33/00
Filed: 2020-06-05
Abstract: Methods for treating neurodegenerative diseases, e.g., Parkinson's disease (PD), with carbon monoxide (CO), e.g., orally administered CO.
Patent WO-2021022042-A1 (WO)
Inventor: HIGGS C
IPC: G01V9/00
Filed: 2020-07-30
Abstract: A method for designing lithology-specific drill bits. The method creates an experimentally verified multiphysics model to predict drilling into site-specific rock formations. A physics-based, Eulerian-Lagrangian computational modeling framework to predict particle flow and tribological phenomena. The method uses this multiphysics model to generate virtual drilling data and then generates a machine learning enabled surrogate model of the physics-based model using the data from virtual drilling to provide design charts for drill bits.
Patent WO-2021030685-A1 (WO)
Inventor: WANUGA KEVIN T
IPC: H04B7/06
Filed: 2020-08-14
Abstract: Methods and apparatuses for receive (Rx) beam selection are described herein. A wireless transmit/receive unit (WTRU) may be configured to receive, from a base station (BS), configuration information for joint communication and sensing (JCS) reference signals. The configuration information may include resources for reference signal transmission and resources for measurement reporting. The WTRU may be further configured to receive, from the BS, an indication to activate a subset of the resources for JCS reference signal transmission. The WTRU may be further configured to transmit, a plurality of JCS reference signals using the activated subset of resources for reference signal transmission. The WTRU may be further configured to measure, via a plurality of Rx beams, a backscatter power associated with each of the transmitted plurality of JCS reference signals. The WTRU may be further configured to calculate beam blockage statistics based on the measured backscatter power.
Patent WO-2021041729-A1 (WO)
Inventor: MICKEAL JEFFREY
IPC: G06F15/16
Filed: 2020-08-27
Abstract: Le système fournit un procédé et un appareil de construction, de commande, de conservation, d'enregistrement, d'affichage et de préservation automatiques d'une discussion entre un, deux ou plusieurs utilisateurs sur un sujet. Le système est un modérateur de débat automatisé qui assure la mise en sourdine, des limites de temps, un nombre de tours, un compte à rebours de durée de tour, un ordre de parole et un temps de fin qui peuvent être accédés par l'intermédiaire d'un quelconque dispositif de traitement, comprenant des téléphones intelligents, des tablettes, des ordinateurs de bureau, des ordinateurs portables et similaires. Les sujets peuvent être auto-générés ou sélectionnés à partir d'une liste de sujets traités et le débat enregistré résultant peut être lié à n'importe quel réseau social ou plateforme de visualisation multimédia.
Patent WO-2021050571-A1 (WO)
Title: Novel nucleobase editors and methods of using same
Inventor: GAUDELLI NICOLE
IPC: A61K31/7088
Filed: 2020-09-09
Abstract: The invention features novel programmable nucleobase editors comprising adenosine deaminase domains and methods of using the same for polynucleotide editing. In some embodiments, programmable nucleobase editors edit a pathogenic mutation associated with a genetic disease.
Patent WO-2022066151-A1 (WO)
Title: Addition of features to screens for forming wet parts with details
Inventor: SHIRLEY NATHAN ERIC
IPC: B33Y80/00
Filed: 2020-09-22
Abstract: According to examples, a processor may obtain a digital model of a screen including pores that is to be implemented in a formation of a wet part from a slurry. The processor may obtain a digital model of a feature to be added to the screen, in which the feature is to impart a detail onto the wet part during formation of the wet part and may incorporate the digital model of the feature with the digital model of the screen. The processor may also identify locations in the digital model of the feature that are in line with pores in the digital model of the screen and modify the digital model of the feature to add pores at the identified locations in the digital model of the feature to extend the pores in the digital model of the screen through the digital model of the feature.
Patent WO-2021067336-A1 (WO)
Title: Method of treatment using synergistic dietary supplements to relieve physical discomfort and pain, or mental discomfort linked to menstruation
Inventor: CRANE MATHEW
IPC: A61K36/28
Filed: 2020-09-30
Abstract: Methods of treating dysmenorrhea and bloating, menstruation, headache, backache, and/or intestinal issues associated with menstruation are provided. Menstrual pain treatment systems are further provided.
Patent WO-2021091655-A1 (WO)
Inventor: MEIER NATHANIEL J
IPC: G11C17/16
Filed: 2020-10-09
Abstract: Memory devices, systems including memory devices, and methods of operating memory devices are described, in which security measures may be implemented to control access to a fuse array (or other secure features) of the memory devices based on a secure access key. In some cases, a customer may define and store a user-defined access key in the fuse array. In other cases, a manufacturer of the memory device may define a manufacturer-defined access key (e.g., an access key based on fuse identification (FID), a secret access key), where a host device coupled with the memory device may obtain the manufacturer-defined access key according to certain protocols. The memory device may compare an access key included in a command directed to the memory device with either the user-defined access key or the manufacturer-defined access key to determine whether to permit or prohibit execution of the command based on the comparison.
Patent WO-2021092333-A1 (WO)
Inventor: KONDURI VANAJA
IPC: A61K35/14
Filed: 2020-11-06
Abstract: Provided herein are methods of expanding CD161 +  T cells. Also provided are methods and compositions for generating modified CD161 +  T cells comprising a chimeric antigen receptor (CAR). In particular aspects, CAR-expressing T cells are produced, expanded, and/or used in disease ( e.g , cancer) treatments.
Patent WO-2021097438-A1 (WO)
Title: Piezoelectric coated implants and methods of using piezoelectric coated implants to repair bone structures
Inventor: HUNT JESSEE
IPC: A61F2/44
Filed: 2020-11-16
Abstract: Various embodiments of implant systems and related apparatus, and methods of operating the same are described herein. In various embodiments, an implant for interfacing with a bone structure includes a web structure, including a space truss, configured to interface with human bone tissue. The space truss includes two or more planar truss units having a plurality of struts joined at nodes. Implants are coated with, or have struts formed from, a piezoelectric material to enhance bone growth around and through the implant.
Patent WO-2021007590-A1 (WO)
Title: Devices and methods for detecting elements in a sample
Inventor: CARIA PIETRO
IPC: G01N15/02
Filed: 2020-07-07
Abstract: Devices and methods are disclosed for identifying compounds using spectra generated by X-rays at two different voltage levels.
Patent WO-2021158510-A1 (WO)
Inventor: LEARISH RANDALL
IPC: A61M5/145
Filed: 2021-02-02
Abstract: L'invention concerne un appareil et des procédés de surveillance et d'administration d'une suspension cellulaire. Dans certains exemples, l'appareil comprend un réservoir contenant la suspension cellulaire, une canule et un mécanisme de transfert de liquide conçu pour transférer la suspension cellulaire du réservoir à la canule. L'appareil peut également comprendre un mécanisme d'agitation pour agiter la suspension cellulaire, et un dispositif de surveillance pour quantifier une concentration de cellules transférées du réservoir à la canule.
Patent WO-2021173820-A1 (WO)
Inventor: GOODSITT JEREMY
IPC: G06F11/36
Filed: 2021-02-25
Abstract: A computer-implemented method may include: receiving first data that may include information associated with an error in an execution of code; based on the first data, determining: for each contributor in a predetermined list of contributors: a respective familiarity value indicative of an amount of association between the contributor and the error in the code; and a respective set of task management statistics; and an urgency value of the error; using an optimization model, selecting at least one contributor from the predetermined list of contributors to assign to the error, the optimization model based on the respective familiarity values and the respective sets of task management statistics for each contributor, and the urgency value of the error; and transmitting a notification indicative of the error to a computing device associated with the at least one contributor assigned to the error.
Patent WO-2021178870-A1 (WO)
Inventor: ELLIS JAMES HOWARD JR
IPC: H01L23/02
Filed: 2021-03-05
Abstract: A magnetic sensor device with an array of magnetic sensors arranged on a common semiconductor substrate to measure the multi-axis magnetic field of an arbitrary region with high spatial resolution, reduced sensing distance, higher measurement throughput, motion tolerance, temperature tolerance, and improved manufacturing yield. A multi-axis magnetic sensor array device fabricated on a common semiconductor substrate is optimized offering additional improvements to reduce measurement time, increase spatial resolution uniformity, and lower thermal compensation cost. Further, the central area of a surface is utilized to measure the normal magnetic field. A perimeter of Hall effect plates measuring the components of the magnetic field in the plane of the measuring surface, which allows for a very high density of normal field measurements allows calculation of the in-plane field components. Error along the edges can be mitigated with the in-plane measured components.
Patent WO-2021202777-A1 (WO)
Inventor: WILDSMITH KRISTIN RUTH
IPC: G01N33/68
Filed: 2021-03-31
Abstract: La présente invention concerne des procédés de mesure et d'analyse de sites de phosphorylation dans la protéine tau et de détermination de corrélations avec d'autres biomarqueurs de la maladie d'Alzheimer et des tauopathies.
Patent WO-2021252084-A1 (WO)
Title: Systems and methods for disengagement prediction and triage assistant
Inventor: LI XIAOJIE
IPC: B60W50/00
Filed: 2021-04-23
Abstract: In one embodiment, a computing system of a vehicle may receive perception data associated with a scenario encountered by a vehicle while operating in an autonomous driving mode. The system may identify the scenario based at least on the perception data. The system may generate a performance metric associated with a vehicle navigation plan to navigate the vehicle in accordance with the identified scenario. In response to a determination that the performance metric associated with the vehicle navigation plan fails to satisfy one or more criteria for navigating the vehicle in accordance with the identified scenario, the system may trigger a disengagement operation related to disengaging the vehicle from the autonomous driving mode. The system may generate a disengagement record associated with the triggered disengagement operation. The disengagement record may include information associated with the identified scenario encountered by the vehicle related to the disengagement operation.
Patent WO-2022005594-A1 (WO)
Title: Method and apparatus for multi-rate neural image compression with micro-structured masks
Inventor: JIANG WEI
IPC: G06K9/00
Filed: 2021-05-03
Abstract: A method of multi-rate neural image compression includes selecting encoding masks, based on a hyperparameter, and performing a convolution of a first plurality of weights of a first neural network and the selected encoding masks to obtain first masked weights. The method further includes encoding an input image to obtain an encoded representation, using the first masked weights, and encoding the obtained encoded representation to obtain a compressed representation.
Patent WO-2022026026-A1 (WO)
Inventor: LEE JEONG
IPC: A61M25/00
Filed: 2021-05-07
Abstract: Aspects of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such aspects can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some aspects can include various configurations of the sheath that comprise an elongated tube having a disclosed composition that can form an outer jacket or a strain relief jacket or can be used as the outer layer of the sheath. Aspects of the present expandable sheath can avoid the need for multiple insertions for the dilation of the vessel and reduce the push force needed for passage of the medical device, thus offering advantages over prior art introducer sheaths.
Patent WO-2021231410-A1 (WO)
Title: Method of treating cancer with telotrisat or a prodrug thereof
Inventor: GOPINATHAN SUMA
IPC: A61P35/00
Filed: 2021-05-11
Abstract: Provided herein are methods of treating cancer with a TPH1 inhibitor. In certain embodiments, methods are provided which display remarkable efficacy and bioavailability for the treatment of certain tumors, for example, a neuroendocrine tumor in a human patient. In certain embodiments, the methods comprising treating the patient with telotristat, a telotristat prodrug, or a pharmaceutically acceptable salt thereof, which can be administered either alone or in combination with other anticancer or antidiarrheal agents.
Patent WO-2021247750-A1 (WO)
Inventor: REICHE CHRISTOPHER F
IPC: G01N27/00
Filed: 2021-06-02
Abstract: A stand-alone point-of-care device can employ smart hydrogel structures to detect target analytes in a fluid sample. The device includes a microfluidic sample slide including a microfluidic channel with one or more smart hydrogel structures positioned within the channel. The slide can be inserted into an associated analytic device, to analyze the swelling state of the hydrogel structures using an optical camera to capture images of the hydrogel structure(s) before and after interaction of such hydrogel structure with the fluid sample. Such optical imaging can be used to quickly and easily measure the dimensional change in the hydrogel structure, which change can be correlated to the concentration of analyte in the fluid sample. Imaging and analytics can be performed by an associated analytic device (e.g., which receives a microchannel slide containing the fluid sample), or imaging and analytics can be accomplished with a smartphone camera and associated app.
Patent WO-2022150057-A1 (WO)
Inventor: TERMANINI ZAFER
IPC: A61F2/34
Filed: 2021-06-14
Abstract: An interlocking reverse hip prosthesis including an acetabular cup having an opening in the central portion of the cup being implanted in the acetabular cavity. The opening has a circular extending wall protruding into the concave portion of the cup a distance at least equal to the diameter of the opening. The inward extension of the cup provides a female Morse taper suited for receiving the male Morse tapered post of the acetabular ball. After implantation of the acetabular cup, the surgeon can easily secure the cup to the acetabular bone using several screws without the interference of the central peg (as in prior implants). The femoral ball is then attached to the cup via central Morse taper.
Patent WO-2022005858-A1 (WO)
Title: Tubular packed-bed cell culture vessels, systems, and related methods
Inventor: WETHERILL TODD MARSHALL
IPC: C12M1/12
Filed: 2021-06-24
Abstract: A cell culture system is provided that includes a bioreactor vessel having an interior void defining a cell culture space, an inlet fluidly connected to a first end of the cell culture space, and an outlet fluidly connected to a second end of the cell culture space; and at least one cell growth element disposed in the cell culture space. The cell growth element includes a cell culture substrate surrounding a support element extending in a direction from the first end to the second end of the cell culture space.
Patent WO-2022005985-A1 (WO)
Title: Aqueous fluid system and method for cleaning and remanufacturing of aftertreatment system components
Inventor: PERRY JUSTIN WYATT
IPC: F01N3/035
Filed: 2021-06-28
Abstract: A concentrated aqueous solution for cleaning a component of an aftertreatment system of an engine system includes an organic acid at a concentration between 25% and 50% mass per volume of the concentrated aqueous solution, and a biological growth inhibitor at a concentration between 0.1% and 1% mass per volume of the concentrated aqueous solution. The concentrated aqueous solution also includes a surface tension modifier at a concentration between 0.1% and 25% volume per volume of the concentrated aqueous solution, and a foam controlling agent at a concentration between 0.01% and 15% volume per volume of the concentrated aqueous solution.
Patent WO-2022015755-A1 (WO)
Title: Medical devices having anti-microbial properties and methods for making the same
Inventor: MURNAGHAN KEVIN
IPC: A61L29/04
Filed: 2021-07-13
Abstract: A medical device comprising a surface, wherein a sulfanilamide is associated with the surface, and methods for making the same.
Patent WO-2022035864-A1 (WO)
Title: Tablet tooling assembly
Inventor: CARPENTER TRENT
IPC: F16B21/08
Filed: 2021-08-10
Abstract: A tablet tooling assembly having a tool body (110) defining a blind bore (112) in a first end, a tool head (130) including a body portion with a main shaft portion (134) and a stem portion (136) extending therefrom, wherein a blind bore i(138) s formed in the stem portion (136), and a detent (120) formed by a catch and a spring, the detent (120) being disposed in the blind bore (138) of the tool head (130) and the spring (124) urging the catch (122) radially-outwardly from the blind bore (138), wherein the stem portion of the tool head (130) is disposed in the blind bore (112) of the tool body (110).
Patent WO-2022036162-A1 (WO)
Title: System and method for automatically generating trajectories for laser applications
Inventor: LUONG CHUONG
IPC: B25J19/02
Filed: 2021-08-13
Abstract: A system for automatically generating trajectories of an object includes a trajectory generation module comprising a visual control algorithm and a processor configured via computer executable instructions to receive raw three dimensional (3-D) sensor data of an object, create a 3-D model of the object based on the raw 3-D sensor data, extract object features relating to a shape and/or surface from the 3-D model of the object, and generate trajectories based on the object features of the 3-D model of the object.
Patent WO-2022046601-A1 (WO)
Inventor: KOR SANDEEP
IPC: H02P6/10
Filed: 2021-08-23
Abstract: Systems and apparatuses include an alternator including a stator and a rotor structured to be coupled to a crankshaft of a prime mover, and processing circuits structured to: determine a crankshaft position, associate a crankshaft timestamp with the crankshaft position, determine a stator voltage waveform position, associate a stator voltage waveform timestamp with the stator voltage waveform position, determine a common time base using the crankshaft timestamp and the stator voltage waveform timestamp, determine a rotor position based on the crankshaft position and associated with the common time base, determine a load angle based on the rotor position and the stator voltage waveform position using the common time base, compare the load angle to a stability limit, and transmit a predicted pole slip signal to at least one of the prime mover or the alternator to inhibit a pole slip event when the load angle exceeds the stability limit.
Patent WO-2022047226-A1 (WO)
Title: Isolation room systems and methods
Inventor: GRIFFITH SAUL THOMAS
IPC: E04H3/08
Filed: 2021-08-27
Abstract: An isolation room system comprising a plurality of walls defining a first chamber; and including an air filtration system that pulls air from within at least the first chamber through a filter.
Patent WO-2022061017-A1 (WO)
Title: Prosthetic valve systems, apparatuses, and methods
Inventor: DASS AJAY KUMAR
IPC: A61F2/24
Filed: 2021-09-16
Abstract: Apparatuses, systems, and methods for prosthetic valves. Embodiments of prosthetic valves may be directed to improvements in anchoring to an implantation site and/or sealing flow at an implantation site, which may comprise a native valve. Embodiments may be configured to conform to a shape of a native valve, which may be a non-circular shape. Such native valves may include native valve annuli having oval shapes and/or shapes that include one or more recesses. Improvements in anchoring to implantation sites are disclosed as well.
Patent WO-2022081324-A1 (WO)
Inventor: LJUNGGREN ANTON
IPC: G06F17/00
Filed: 2021-09-24
Abstract: L'invention concerne un procédé de sélection et de distribution sans contact d'une boisson personnalisée à l'aide d'un dispositif électronique mobile. Le procédé comprend le lancement d'un microsite sur le dispositif électronique mobile. Le procédé comprend aussi la réception d'une sélection de boisson par l'intermédiaire du microsite sur le dispositif électronique mobile, et la réception d'une sélection d'un volume de la boisson personnalisée à distribuer par l'intermédiaire du microsite. Le procédé comprend aussi la production d'un code QR par l'intermédiaire du microsite, le code QR correspondant à la sélection de boisson et à la sélection de volume et l'affichage du code QR sur un affichage du dispositif électronique mobile de sorte que, lorsque le code QR est lu par un lecteur d'un distributeur de boissons, le volume sélectionné de la boisson sélectionnée est distribué en fonction du code QR.
Patent WO-2022067213-A1 (WO)
Title: High-temperature cryosurgery system and methods of using the same
Inventor: BARKEN ISRAEL
IPC: A61B18/02
Filed: 2021-09-27
Abstract: A high temperature cryosurgery system and method of operation comprising a refrigeration assembly, a cryoprobe and a refrigerant wherein the cryoprobe and the refrigeration assembly are fluidly coupled in a closed loop configured to cycle the refrigerant in a fluid state from the refrigeration assembly to the cryoprobe and further configured to cycle the refrigerant in a vapor state from the cryoprobe to the refrigeration assembly. A method for treating cancer tumors and metastatic cancer cells by disrupting the tumor by sequentially or concurrently administering an ablative energy in combination with immunomodulation and/or pharmacological application, in one or more cycles, where the physical disruption is applied at levels sufficient to create the abscopal effect. That effect is generated by stimulating the immune cells in the microenvironment. The tumor is treated in a way permitting the remaining cells or elements in the tumor microenvironment to exert net immune stimulation with also long-term memory cells to fight subsequent appearing tumor in the future. Adding immune modulators injected in situ systemically or embedded in slow releasing means locally or systemically will boost the immune response to the cancer.
Patent WO-2022072318-A1 (WO)
Inventor: PALASIS MARIA
IPC: A61F2/95
Filed: 2021-09-28
Abstract: The present invention relates to implantable devices, as well as their methods of use and manufacturing, having osmotic capabilities. Exemplary embodiments of the present invention include fiber and sheet based implantable devices for drug delivery to bodily lumens.