baber/WOPTO huggingface dataset:
Patent DO-P2023000096-A (DO)
Title: Anticuerpo biespecífico anti-tspan8/anti-cd3 y anticuerpo anti-tspan8
Inventor: YOSHIYUKI TENDA
IPC: A61K39/395
Filed: 2023-05-15
Abstract: Proporciona un anticuerpo anti-TSPAN8/anti-CD3 específico y un anticuerpo anti-TSPAN8 utilizable en el tratamiento o prevención en un ser humano. 	Se inmunizó un ratón productor de anticuerpos monoclonales humanos con una célula cancerosa diseminada peritoneal aislada de un paciente, para obtener un anticuerpo 16B11 y un anticuerpo 16B12 que se unen selectivamente a una célula cancerosa diseminada peritoneal. Estos anticuerpos eran anticuerpos anti-TSPAN8 que se unen a la región de las posiciones de aminoácidos 126 a 155 de TSPAN8 y mostraron una fuerte actividad de unión a TSPAN8 expresada en la célula cancerosa diseminada peritoneal. 	Además, un anticuerpo biespecífico anti-TSPAN8 (16B11) -anti-CD3 producido sobre la base de la secuencia de 16B11 exhibió una actividad citotóxica contra la célula cancerosa que expresa TSPAN8 in vitro, ejerció una acción antitumoral en ratones portadores de células cancerosas que expresan TSPAN in vivo, y prolongaron la vida útil de los ratones modelo de diseminación peritoneal.
Patent EE-202100015-A (EE)
Title: A method and apparatus for determining physiological parameters of a body organ within a convex shaped body part
Inventor: MIN MART
IPC: H01F38/28
Filed: 2021-05-17
Abstract: The subject of the invention is a method and apparatus for determining physiological parameters of a body organ within a convex shaped body partplaced into a coil with toroidal core that follows the convex shape of the body from 1/10 to full extent (1/1) of the convex, inducing alternating current response signal and determining the physiological parameters of the body organ from the response signal.
Patent GB-189701462-A (GB)
Title: A Protector or Strengthener for Corset Clasping Steels.
Inventor: TILTON-NEE-ANDREWS CHLOE FRANC
Filed: 1897-01-19
Granted: 1897-03-13
Abstract: 1462. Tilton, C. r., [nÞe Andrews]. Jan. 19, Corsets.-To strengthen corsets at the waist part, a metal strip D is sprung between or against two of the fastening-studs a, b on the busk C before the same are fastened to the loops on the other busk. Figs. 2, 3, and 4 show various forms of and methods of using the strip D.
Patent GB-189707515-A (GB)
Title: Improvements in Indexing Machines.
Inventor: THOMPSON WILLIAM PHILLIPS
Filed: 1897-03-23
Granted: 1897-05-29
Abstract: 7515. Thompson, W. P., [Webb, S. N.]. March 23. Platen presses.-Stepped indexes for books are cut and printed by a machine shown in side elevation in Fig. 1. The book to be operated upon is placed upon a table 3 against a support 3<h> adjustable upon the table by means of a screw actuated by gearing 3<c>, 3<d> and handle 3<a>. A presser plate 7 for holding the book is connected by a rod 7<d> to a treadle 7<c>, and is normally held in the raised position by a weight 7<f> which is carried by a pivoted lever 7<4>. A rotary frame 4 carrying type - arms 4<b> and gouge-shaped cutters 4<d> is mounted in reciprocating frames B<1> connected by rods 6<b> to discs 6 on a shaft 6<a>. The cutters are adjustably attached at suitably-graded positions to a bar 4<1>, carried by the printing-frame, and the type-arms are affixed to a similar bar 4<2>, so as to print on the face of the leaves just below those which have been gouged. Motion is transmitted from the main shaft 2 through gearing 2<a>, 2b to the shaft 6<a>. During the upward strokes of the frame 4, the latter is rotated through an angle of 90‹ by means of a swinging bar or hanger which engages with one of four radial ribs formed on the frame ; at other times the frame is locked by an automatically-actuated pin. An inking-pad 10 is loosely mounted on posts 10<a>, each of which is encircled by a spring 10<b>. The machine shown in Fig. 1 cuts and prints two indexes during every revolution, and is then automatically thrown out of gear by clutch mechanism.
Patent GB-189707823-A (GB)
Title: Improvements in Electric Switches.
Inventor: COWAN EDWARD WOODROWE
Filed: 1897-03-26
Granted: 1898-02-12
Abstract: 7823. Cowan, E. W., and Still, A. March 26. Switches for circuits having considerable selfinduction such as the fields of dynamos, motors, &c. To prevent sparking &c., a resistance is first inserted in series with the circuit, which is then short-circuited, and finally the supply disconnected. Figs. 1 and 2 show the construction, and Fig. 3 a diagram of the connections. The switch is shown ' on.' To break the circuit, the handle is pulled over, the first effect being to remove the lever B from the contacts b, so inserting the resistance R, which has but little self-induction. Next the circuit L is short-circuited at c, c, and, finally, the main circuit is broken at k, k by the lever striking the cross-bar D. A spring is arranged to give a quick break.
Patent GB-189710455-A (GB)
Title: An Improved Composition Applicable for Securing Pavement Lights and other purposes.
Inventor: MILLS FRANK
Filed: 1897-04-27
Granted: 1897-07-03
Abstract: 10,455. Mills, F., and Trickett, F. April 27. Pavement-lights.-A flexible damp-proof composition for securing pavement-lights &c. is obtained by boiling gas tar or Stockholm tar, resin, pitch, and sulphur together. The composition is applied in a hot liquid state, and creosote oil or spirit of tar may be added to make the mixture run freely.
Patent GB-189718280-A (GB)
Title: Improvements in Oil, Vapour, or Spirit Cooking Stoves.
Inventor: GISBERT FRANCISCO JAVIER DE
Filed: 1897-08-05
Granted: 1897-10-02
Abstract: 18,280. Gisbert, F. J. de. Aug. 5. Oil or spirit cooking- stoves, portable.-The various parts of an oilvapour or spirit stove are made detachable so as to be easily packed. The feet i attached to the reservoir have sockets for the supports d, on which the ring c rests. The burner b, which screws into the reservoir, is of the form described in Specification No. 17,977, A.D. 1896.
Patent GB-189724770-A (GB)
Title: Improvements in the Apparatus for Drying Moulds and Cores for Castings.
Inventor: LITTLLTON WILLIAM
Filed: 1897-10-26
Granted: 1898-07-23
Abstract: 24,770. Littleton, W. Oct. 26. Casting and moulding.-Relates to means for drying moulds and cores. A current of hot air is forced through the mould, the air being heated by the apparatus shown. Gas is supplied through D and air under pressure through C to the burner A, and a further quantity of air is drawn through the openings E and mixes with the products and enters the mould.
Patent GB-189725807-A (GB)
Title: Improvements in and Relating to the Covers of Sheet Metal Cans and similar Vessels.
Inventor: FLIEGEL JOSEF
Filed: 1897-11-06
Granted: 1898-02-05
Abstract: 25,807. Fliegel, J. Nov. 6. Milk cans.-The neck of the vessel is provided with a ring a of porcelain, glass, or other ceramic material, and is closed by a disc cover d, also of porcelain &c. The ring a is cemented in position, and the ring and cover are ground flat at a, d<1> respectively, so that, when the cover is placed in position, it hermetically closes the vessel. As shown in Fig. 2, the cover is secured in position by the usual closing-lever k, which is pivoted eccentrically and bears on the metal plate e affixed to the cover.
Patent GB-189728466-A (GB)
Title: Manufacture of Ceramic, Earthenware, Porcelain, Stoneware, Glass, Crystal, and such like Ware with Metallic Decorations, and Furnaces or Ovens therefor.
Inventor: KELLER CHARLES
Filed: 1897-12-02
Granted: 1898-11-26
Abstract: 28,466. Keller, C., and Keller, A. Dec. 2. Pottery; slabs; enamels.- Relates to the decoration of earthenware, stoneware, porcelain, glass, and like ware with ornaments or designs of gold, silver, nickel, or other metal. Slabs or medallions C are moulded with grooves, and, after baking, the grooves or faces are coated with fusible cement or enamel, the designs or monograms d are inserted in the grooves, and the articles are heated in a muffle. The cleaned metal surfaces are coated with ochre before the articles are placed in the muffle, to prevent fusing of the metal and the running of enamel over the surface. Metal ornaments in relief may be secured to the smooth surfaces of vases or other articles by enamel in a similar manner. A hard composition for uniting the metal to porcelain is made by mixing 100 parts by weight of silica, 100 parts of binoxide of lead (minium), 34 parts of carbonate of potash, and 40 parts of borax in a crucible. For a soft composition, 100 parts of sand are melted with 200 parts of binoxide of lead and 50 parts of borax. To the above ingredients may be added nitre, carbonate of soda, carbonate of lime, sodium chloride, and more carbonate of potash.
Patent GB-189729441-A (GB)
Title: Improvements in Flanges for Warpers' and Weavers' Beams and like purposes.
Inventor: PRESCOTT THOMAS
Filed: 1897-12-13
Granted: 1898-11-26
Abstract: 29,441. Prescott, T. Dec. 13. Warp beams.-Flanges are formed of a dished plate a, having a wooden or other ring c secured to it by expanding the central web e, and a domeshaped plate f secured to it by riveting the edges together or otherwise. The central portion of the plate f may be secured to the ring c by bolts r or screws, which may also be used for fixing a boss to the flange.
Patent GB-189804105-A (GB)
Title: Improvements in and connected with Motor Tricycles or Carriages.
Inventor: SIMMS FREDERICK RICHARD
Filed: 1898-02-18
Granted: 1898-12-10
Abstract: 4105. Simms, F. R. Feb. 18. Drawings to Specification. Coupling; jinrickshaws.-When a motor vehicle is coupled to a jinrickshaw, the latter is provided with converging shafts which are pivoted to a socket mounted on the end of the steering-stem of the rear steering-wheel. The jinrickshaw frame is composed of bent tubes, to which is attached a light body supported on C-springs. Supports may be provided for lowering to the ground.
Patent GB-189806516-A (GB)
Title: Improvements relating to the Fixing of Rain-water and other Pipes.
Inventor: THOMERSON CHARLES
Filed: 1898-03-17
Granted: 1898-05-20
Abstract: 6516. Thomerson, C. March 17. Metal pipes; holdfa.sts. - The invention relates to distance-pieces interposed between the lugs of a fall pipe and the wall to which it is attached, so as to leave a space between the wall and the pipe. The block e is temporarily fixed to the wall by a pin g until it is finally fixed by the nail, which passes through a hole f and through the hole in the pipe lug.
Patent GB-189813541-A (GB)
Title: Improvements in or relating to Coin-freed Apparatus for Displaying Cards, Advertisements, and other Articles.
Inventor: SCHIELE JOSEPHA
Filed: 1898-06-17
Granted: 1898-09-03
Abstract: 13,541. Schiele, J., and Hackelberg, S. June 17. Advertising.-Advertisements or other articles are displayed on the front of coin-freed apparatus, the articles being held by catches a until released by dropping a coin into the apparatus. Each catch or slide a has a hook a<1>, which is passed through the article, and which, when the slide is pushed back, passes through an aperture in the front of the apparatus. When pushed back, the catch is held in position against the pressure of a spring a<3>, which tends to push it outwards, by a lever b which engages with a shoulder a<4> on the catch. A coin dropped through the slot B falls on the pan c<4> of the lever c<2>, c<3>, thus lifting the lever b and releasing the catch.
Patent GB-189819653-A (GB)
Title: An Improved Dog Collar.
Inventor: WOOD JAMES ROBERT
Filed: 1898-09-16
Granted: 1899-07-22
Abstract: 19,653. Wood, J. R. Sept. 16. Dog collars.-The collar consists of a chain A, wire, or wire cord encased in a flexible tube of rubber &c. B. The ends of the chain may protrude through caps C, C, and be fastened by a padlock &c., or the sliding fastening shown in the Figure may be used. One end of the collar may have a small chain, so that the same collar may be made to fit dogs of different sizes and the license badge may be secured to this chain.
Patent GB-189820916-A (GB)
Title: Improvements in Race Tracks for Dogs and other Animals.
Inventor: WALSH MICHAEL
Filed: 1898-10-04
Granted: 1899-07-22
Abstract: 20,916. Walsh, M. Oct. 4. Tracks for sporting purposes.-Tracks are provided for dogs or other animals to race in, dummy hares or other objects being propelled in advance and in full sight of the animals. The Figure shows a double track A, A' enclosed by suitable fences and situate on each side of a railroad along which a motor car D is run. From the latter flexible arms support platforms G, G<1> on which the racing dummy is placed. A judge's box, from which the speed of the motor may be controlled, and a stand for spectators are provided. Suitable means other than a motor may be employed for running the dummies.
Patent GB-189821397-A (GB)
Title: Improvements in or connected with Fruit and like Baskets.
Inventor: BLAMPIED CHARLES
Filed: 1898-10-11
Granted: 1899-08-12
Abstract: 21,397. Blampied, C., and Rossignol, A. P. Oct. 11. Fruit baskets. -To facilitate the stringing of fruit baskets, they are fitted with hooks or eyes beneath the rim and preferably on the outside of the basket. The shanks b<2> of the wire hook b may be twisted round one of the uprights a<3>, or be bent upwards and downwards and held by means of the horizontal interlaced portions of the basket. The hooks may be formed upon a length of wire, which is passed completely round the basket and interlaced with the uprights thereof ; or they may be each formed from a piece of sheet metal, the shank of the hook being pierced with an aperture through which passes one of the vertical uprights a<3>. Or all the hooks may be formed on a strip or band of metal, which passes completely round the basket and is provided with auxiliary hooks, which engage with the horizontal interlaced portions of the basket and prevent the band from being drawn upwards.
Patent GB-189821554-A (GB)
Title: Improved Discharge Opening and Door for Vats.
Inventor: JAMES ALFRED
Filed: 1898-10-13
Granted: 1898-12-03
Abstract: 21,554. James, A. Oct. 13. Metals, extracting; gold. - Relates to discharge openings and doors for vats such as those used in the lixiviation of gold or other ores by chemical solutions. The flanged ring a forms the internal opening, and is bolted through the bottom b to the flange e, which contains a packing-ring f. The lid i is made of pressed steel, is attached to the vat by a chain, and has secured to it the cross-bar n by which it is held in place in the closed position shown in Fig. 1. Tightening is effected by turning the screw bolt o, which passes through the nuts p, q. When the bolt o is loosened and the cross-bar n turned out of engagement with the brackets g, the lid i falls away from the opening, and hangs by its chain.
Patent GB-189900596-A (GB)
Title: Improvements in Pneumatic Tyres.
Inventor: DRISCOLL JAMES HILORY
Filed: 1899-01-10
Granted: 1899-06-10
Abstract: 596. Driscoll, J. H. Jan. 10. Tyres, pneumatic.-Relates to tyres for the wheels of heavy vehicles. The inner tube 15 is made in two semicircular portions with caps 17 of linen or the like connected by a tape 18. The outer tube 1, Fig. 4, is formed with two flaps 2 having perforations 5, and is itself perforated at 6, 7 close by the flaps. The ends of the deflated tube 15 are passed in turn into the outer tube through the flaps and worked round till the nipple 16 is opposite the hole in the rim 4. A plate 8 is then placed between the inner and outer tubes, and the bolt 9 passed through the hole 5. Lastly, the plate 12 is placed over the flap, the hole 13 receiving the bolt 9 and the pins 14, 14 entering the holes 6, 7, and the nut 10 is screwed down.
Patent GB-189905282-A (GB)
Title: Improvements in Thread Cutters.
Inventor: MACDONALD JOHN KING
Filed: 1899-03-10
Granted: 1899-04-29
Abstract: 5282. Macdonald, J. K., [Singer Manufacturing Co.]. March 10. Shears for thread-cutting. Consists of a cutter for removing the surplus thread between groups of stitches formed in sewing on buttons, or in like work, in sewing-machines. The blades B, connected to the arms b<1> of the handle B', work against the sides of the flat tapering blade A, connected with the handle A<1>, and adapted for insertion under the surplus length of thread. The cutter is held open by a spring between the handles.
Patent GB-189912150-A (GB)
Title: Improvements in Incandescent Gas Burners.
Inventor: LERY JOSEPH BLASCO DE
Filed: 1899-06-10
Granted: 1899-08-26
Abstract: 12,150. LÚry, J. B. de. June 10. Incandescent gas lamps.-Tho usual stocking- shaped mantle is replaced by tassels or the like formed by cutting loops or strips b, Fig. 1, from a flattened loop a of the prepared fabric, stretching the loop b to curl the edges c outwards, Figs. 2 and 3, turning the edges inwards, Figs, 4 and 5, bending the loops b to form single or, preferably, double tassels, Figs. 8. 9, 10, and 11, and securing them upon the eyelets d of the carrier k. The complete burner is shown in Fig. 12. By forming the tassels from loops b which are uncut at their lower ends w the disintegration of the tassels is minimized.
Patent GB-189922910-A (GB)
Title: An Improved Stand or Support for Displaying Advertisement or Show Cards, Photographs, and the like.
Inventor: WRIGHT GEORGE
Filed: 1899-11-16
Granted: 1899-12-30
Abstract: 22,910. Wright, G. Nov. 16. Stands, card, photograph, and like.-A stand consisting of a strip, bent as shown, with a front a, flange b, and leg d is used for supporting advertisement o r show cards, photographs, and the like.
Patent GB-190003886-A (GB)
Title: Improvements connected with Fire Alarm Thermostats.
Inventor: HEAPHY THOMAS MUSGRAVE
Filed: 1900-02-28
Granted: 1901-02-23
Abstract: 3886. Heaphy, T. M. Feb. 28. Testing fire - alarm circuits, by heating the thermostats by an auxiliary battery. The thermostats a, a consist of mercury thermometers with platinum wire terminals which are connected when the mercury is expanded by heat. In testing, a resistance g surrounding the bulb is heated by current supplied f r o m a n auxiliary battery r by closing a special switch p, q, associated with each bulb. When the thermostat has been sufficiently heated, it can be seen whether an electromagnet h in the alarm circuit is sufficiently energized.
Patent GB-190005248-A (GB)
Title: Improvements in Furnaces.
Inventor: THARAUD EDOUARD
Filed: 1900-03-20
Granted: 1900-04-28
Abstract: 5248. Tharaud, E. March 20. Grates.-Relates to movable or shaking grates, and more particularly to means for raising such grates. The grate 3 is supported on a bar 2, which passes through a slot 1 and is secured to a rack 4 outside the furnace. The rack may be raised and lowered by a toothed segment 5 and handlever 6 as shown, and may be clamped in any position by the screw 7.
Patent GB-190006678-A (GB)
Title: Improvements in Cruet Frames to Facilitate the Packing thereof.
Inventor: COX WALTER CHARLES
Filed: 1900-04-10
Granted: 1900-06-30
Abstract: 6678. Cox, W. C. April 10. Cruets.-Relates to a cruet frame adapted to be taken to pieces to facilitate packing. The baseplate, Fig. 4, is connected to the ring frame, Fig. 1, by a handle, Fig. 2, which passes down through two holes A, Fig. 1, and is fastened by screws D at the base. Tubes, Fig. 3, are used as distancepieces between the ring frame and base-plate.
Patent GB-190006800-A (GB)
Title: Improvements in Apparatus for Purifying Water for Industrial and other Purposes by Means of Heat.
Inventor: PECK SAMUEL
Filed: 1900-04-11
Granted: 1901-02-23
Abstract: 6800. Peck, S., [Carroll, J. E.]. April 11. Feedwater, heating and purifying. -Relates to apparatus for purifying water for steam generators and other purposes, in which the water is heated by passing through tubes B surrounded by steam, and is then passed through a settling-chamber D. Multiple-way valves at I, H, and K are connected by gearing so that all are moved simultaneously to their appropriate positions, and the connections between the handwheel L and the gearing is of a ratchet nature, so that the different operations must always occur in proper order. The gearing is connected to a recording apparatus to record the number and time of the different operations. These operations comprise entrance of cold water at I and its discharge at K, entrance of steam for blowing out at I and K and its discharge at H, entrance of hot boiler water at I, and discharge of displaced steam at H. Suitable valves are shown. Baffle-plates c are provided, or the tubes are connected by bends. The heater may be connected to a boiler or may be placed in it. Where condensed exhaust steam is utilized, it is first run through a settling tank, to allow of the deposition of most of the oil.
Patent GB-190007528-A (GB)
Title: Improvements in Rotary Pumps.
Inventor: ALLISON CHARLES ARTHUR
IPC: F01C1/12
Filed: 1900-04-24
Granted: 1900-05-26
Abstract: 7528. Allison, C. A, [Roots Co., P. H. & F. M.]. April 24. Roots'-blower type.-A rotary pump of the Roots blower type, which can be used as a blower or exhauster, is shown in Fig. 1. The drums 3 are formed with lobes 4 concentric to the shafts 2 and with wide hubs 5. The curved outlines of the drums are shaped so that the contact between the adjacent surfaces of the drums is increased, which prevents the inclusion of fluid between the surfaces.
Patent GB-190008123-A (GB)
Title: Improvements in & connected with Electric Light Wall Plugs.
Inventor: OPPENHEIMER HERMANN
Filed: 1900-05-02
Granted: 1901-03-09
Abstract: 8123. Oppenheimer, H.; [Actiengesellschaft Mix & Genest]. May 2. Couplings.-A wall plug is formed with a base of china or the like having two lateral recesses b, which are each met by two descending openings c, d. In each recess b is fitted a terminal piece e, drilled and fitted with a screw g to fix the line-wire and also drilled to receive the socket k. In a modified form, the line-wire is led in through a hole in the base.
Patent GB-190019277-A (GB)
Title: Improvements in Sad Irons.
Inventor: GREENAWALT PETER C
Filed: 1900-10-27
Granted: 1901-01-19
Abstract: 19,277. Greenawalt, P. C. Oct. 27. Ironing.-Relates to hand-irons with detachable handles. Fig. 1 shows a sectional elevation, and Fig. 2 a sectional plan. The wooden handle B is secured to the plate B' provided with a pendant elliptical plate b<1>, having its long axis at rightangles to the plane of the handle, so that, when it is passed through the opening a<4> in the plate a' and given a quarter turn, the handle is in its right position. The plate C attached to the spring G carries lugs c' which enter slots at the ends of the opening a' when the handle is in place, and prevent it from turning.