baber/WOPTO huggingface dataset:
Patent ES-517886-A0 (ES)
IPC: A61K31/495
Filed: 1982-12-02
Abstract: Diphenylbutyl-1-piperazinocarboxylates of the formulawherein R is alkyl straight or branch chained having from 1 to 10 carbon atoms, cycloalkyl having from 3 to 8 carbon atoms, aralkyl having from 7 to 9 carbon atoms or phenyl unsubstituted or substituted by one to three F, Cl, Br, lower alkyl having from 1 to 5 carbon atoms, lower alkoxy having from 1 to 5 carbon atoms, alkylenedioxy having from 1 to 3 carbon atoms, -CF<sub>3</sub> or -CN substituents, R,-R<sub>4</sub> are independently H, CH<sub>3</sub>, C<sub>2</sub>H<sub>5</sub> with cis or trans configuration provided that only two of them are other than hydrogen, and pharmaceutically acceptable salts thereof are described. Processes for their preparation are also described.The compounds are useful for treatment of mental disorders, such as aggression and psychosis in mammals.
Patent ES-528846-A0 (ES)
IPC: H02K21/18
Filed: 1984-01-13
Abstract: The invention relates to an electric motor having a U-shaped stator iron such as a series-, split-pole- or single-phase synchronous motor. Between the free shank ends of the stator, pole shoes are formed, and on the shanks, induction coils are provided. The shanks of the stator iron in the area between the pole shoes and the coils are bent with respect to the central plane of the stator iron in such manner that the shaft of the rotor with the central plane of the stator iron encloses an angle differing from the perpendicular to the central plane.
Patent ES-530635-A0 (ES)
IPC: C07F9/40
Filed: 1984-03-15
Abstract: Phosphorus containing compounds of the formulawherein X is a substituted or unsubstituted imino or amino acid and A isThese compounds possess angiotensin converting enzyme activity and are thus useful as hypertensive agents.
Patent ES-554621-A0 (ES)
IPC: C07C405/00
Filed: 1986-04-30
Abstract: Prostaglandin derivatives, and specifically derivatives of isocarbacyclin, have an optionally substituted methylene group as a substituent on the  alpha -carbon atom of the  alpha -side chain. They have a variety of physiological effects, notably a strong ability to inhibit blood platelet aggregation and a strong anti-ulcer activity.
Patent FI-833647-A0 (FI)
Inventor: PERREGAARD JENS KRISTIAN
IPC: C07D211/22
Filed: 1983-10-07
Abstract: Novel phenylindene derivatives of the present invention are represented by the following formula: 
<CHEM>
 wherein the dotted lines indicate optional bonds;
 R<1> is hydrogen, halogen, lower alkyl, lower alkoxy, hydroxymethyl, lower alkoxymethyl, cyano, trifluoromethyl, lower alkylthio or lower alkylsulfonyl;
 R<2> is halogen, lower alkyl or trifluoromethyl; and
 R<3> is hydrogen, alkyl or alkenyl (straight or branched chain with C1-C6 inclusive) optionally substituted with one or two hydroxy groups, any hydroxy group present being optionally esterified with an aliphatic carboxylic acid having from two to twenty-four carbon atoms inclusive, or R<3> is 
<CHEM>
 wherein Z ist NR<4>, O or S, where R<4> is H or lower alkyl, and W is O or S, as well as pharmaceutically acceptable acid addition salts of the compounds of Formula I. 
<??>The phenylindene derivatives of Formula I have interesting pharmacodynamic properties indicating strong antipsychotic activity. 
<??>Methods for the preparation of said derivatives are also described, as well as novel intermediates, wich are useful in the methods.
Patent FI-853245-A0 (FI)
Inventor: ROETYNCK MICHEL
IPC: B01F15/02
Filed: 1985-08-22
Abstract: 1. Installation for the preparation, preferably discontinuously, of starch glues, particularly for the manufacture of corrugated cardboard comprising essentially a vessel (1) with substantially vertical axis (X, Y) equipped with stirring means (2) acting at a lower level of the vessel as well as means for supplying the latter with all constituents of the glue to be manufactured and particularly with starch employed in the dry state in the form of powder led in a direction substantially parallel to the vertical axis of the vessel to the level of the stirring means by pneumatic means by a piping (12) which, at a level above the vessel, is cranked to the bottom which installation is characterized by the fact that the piping (12) through which the starch arrives, passes through the wall of the vessel from the outside to the inside of the latter at a level close to the lower part of the vessel (1) and in the vicinity of stirring means (2) included by the latter.
Patent FI-854886-A0 (FI)
Inventor: HOLTSHOUSEN PETER DAVID
IPC: A61K33/18
Filed: 1985-12-11
Abstract: A topical, antibacterial cream contains an antibacterial agent and a base, the base having a 20 to 50% (w/w) content of hydrocarbon and polyol moisturising components. Preferably the antibacterial agent is an iodophor, especially povidone iodine, and the base contains a mixture of liquid and white petrolatum (as the hydrocarbon component) together with glycerine (as the polyol).
Patent FI-900460-A0 (FI)
Inventor: SIMONS RAYMOND GARY
IPC: C08J5/22
Filed: 1990-01-30
Abstract: A low electrical resistance bipolar membrane formed by the conjoining of treated anion and cation exchange membranes is disclosed. The treatment comprises contacting the membranes with an aqueous solution of at least one cation prior to conjoining and contacting at least one face of the membranes with an aqueous alkaline solution. A process for the preparation of acid and alkali using these bipolar membranes is also disclosed.
Patent FI-901140-A0 (FI)
Inventor: NEUMULLER KONRAD
IPC: A47C7/44
Filed: 1990-03-07
Abstract: The device (1) to prevent unintentional movements of surfaces (17, 18) which are movable towards each other essentially comprises a cylindrical casing (2) with crosspiece heads (5) connected to said casing and extending in a transverse direction and a safety mechanism (3) within said casing for a screw (4) capable of being retracted into and extended from said casing which screw is connectable via a T-shaped crosspiece to a second surface part.
Patent FI-902168-A0 (FI)
Inventor: DAVE JAYANT C
IPC: A23G4/06
Filed: 1990-04-30
Abstract: The present invention includes a method of enhancing the flavor of a mint flavored chewing gum by the addition of a minor amount of cocoa powder, as well as the chewing gum so produced. The amount of cocoa powder is selected so as to cause the flavor enhancement and so as to not impart a detectable chocolate flavor to the chewing gum. The level of cocoa powder added is between about 0.08 and 0.5 percent by weight of the chewing gum.
Patent FI-903512-A0 (FI)
Inventor: LANHAM SAMUEL E
IPC: B65D51/20
Filed: 1990-07-11
Abstract: An innerseal liner for containers is provided which permits the removal of the entire liner from the mouth of a container without any tearing of the liner. The innerseal liner is sealed to the mouth of the container and a portion of the outer circumference of the liner overhangs the outer surface of the mouth of the container. A pull tab (15) is integrally formed with the innerseal liner and at the intersection of the pull tab with the circular portion of the liner are cut-outs (16, 17) in the circular periphery of the liner. The cut-outs (16, 17) in arc-shaped and are of a depth approximately the same as the width of the overhang portion (18) of the innerseal liner so that when the pull tab is pulled, the innerseal (14) is removed from the mouth of the container along an arc approximately equal to the width of the pull tab and the length of the cut-cut portions before the overhang portion (18) of the liner is lifted from the mouth of the container.
Patent FI-925692-A0 (FI)
Inventor: ROOS STURE GOESTA
IPC: H04Q11/04
Filed: 1992-12-15
Abstract: The invention relates to a method and a device for testing and supervising majority votes in a multiplane digital time selector with essentially identical equipment in each of at least three planes (A,B,C) working in parallel. An incoming data flow is distributed to the planes and is allowed to pass through the equipment in each of them and gives rise to outgoing data streams. These outgoing data streams are compared to each other and a majority voted outgoing data flow based upon the comparison is delivered from the unit. An error is periodically introduced in accordance with a predeterimed pattern in the three planes and the data streams arriving at the majority vote and the majority voted data flow are compared. If an error is then found in any of the data streams an alarm is emitted. If an alarm (LARM1) is expected that has been caused by an error introduced in accordance with the predetermined pattern, this alarm is identified based upon knowledge of the predetermined pattenr in order to distinguish from alarms, which result from errors not introduced in accordance with the pattern. <IMAGE>
Patent FI-934113-A0 (FI)
Inventor: JOLMA PETRI
IPC: H04W56/00
Filed: 1993-09-20
Abstract: PCT No. PCT/FI94/00415 Sec. 371 Date May 22, 1995 Sec. 102(e) Date May 22, 1995 PCT Filed Sep. 19, 1994 PCT Pub. No. WO95/08901 PCT Pub. Date Mar. 30, 1995A mobile station, and a method for making a handover in a CDMA cellular radio system, which includes in each cell at least one base station connected to the mobile stations in the cell. The connection includes both a traffic channel and one or more control channels. The transmissions of the base stations are not synchronized with each other. A mobile station, after having established a simultaneous connection with two or more of the base stations while making a handover, transmits to the base stations using the same spreading code. The signals received by the base stations are combined in a base station controller, or the like. The base stations with which the mobile station communicates simultaneously, transmit to the mobile station each using a different spreading code. The mobile station receives and demodulates each of the signals, transmitted with different spreading codes, by a different rake receiving unit independent of the other units, each receiving unit being synchronized with the signal from the base station it is receiving. The mobile station combines the signals it has received from the base stations and demodulated by using its plural rake receiving units.
Patent FI-943019-A0 (FI)
Inventor: ARMITAGE BERNARD JOHN
IPC: A61K31/435
Filed: 1994-06-22
Abstract: PCT No. PCT/EP92/02901 Sec. 371 Date Jun. 3, 1994 Sec. 102(e) Date Jun. 3, 1994 PCT Filed Oct. 12, 1992 PCT Pub. No. WO93/13097 PCT Pub. Date Jul. 8, 1993.This invention relates to compounds of formula I and pharmaceutically acceptable salts thereof kyl, hydroxy, carboxyalkenyl, alkoxycarbonyalkenyl, hydroxyalkyl, carboxyalkyl, alkoxycarbonylalkyl, alkoxy, halogenated alkyl, carboxy alkoxycarbonyl or alkanoylamino; R2 represents hydrogen, halo, alkoxy, hydroxy, alkanoyloxy, or phenoxy; R3 represents hydrogen or alkyl; R4 represents hydrogen, halo, alkoxycarbonyl, a benzyloxycarbonyl, alkanoyl, benzoyl, carbamoyl, alkyl, carboxy, hydroxyalkyl or alkylthio; R5 represents hydrogen or alkyl; R6 represents hydrogen, alkyl [optionally substituted by one or more of the following: hydroxy, halo or an amino group of formula -NR12R13], a C3-12 alicyclic hydrocarbon group, phenyl, (cycloalkyl)alkyl or benzyl; R7 represents hydrogen, halo, trifluoromethyl, trifluoromethoxy, alkyl, carboxy, or alkoxy; R8 represents hydrogen, halo, trifluoromethyl, trifluoromethoxy, alkyl or alkoxy; and R9 represents hydrogen or alkyl; which are antirheumatic agents. Compositions containing these compounds and processes to make them are also disclosed.
Patent FI-945326-A0 (FI)
Inventor: WARD JOHN W
IPC: C10G47/16
Filed: 1994-11-11
Abstract: The selectivity of a midbarrel hydrocracking process for middle distillates is significantly increased by using a catalyst containing a Y zeolite that has been exchanged with rare earth cations. The rare earth-exchanged Y zeolite has a unit cell size below 24.45 angstroms and/or a water vapor sorptive capacity less than 10 weight percent at 25 DEG  C. and a p/po value of 0.1.
Patent FI-952242-A0 (FI)
Inventor: CALVERT BARRY GENE
IPC: B65D85/72
Filed: 1995-05-09
Abstract: Container and lid assembly (20), has paperboard container (8) with a polymer coating located on predetermined areas (12) of the outer surface of its base and a peripheral wall extending upward from the edges of the outer surface. The lid (2) of the assembly also has a polymer coating (6) over first and second sections of one side, the first section (14) covering a vessel opening and overlapping the peripheral wall of the container and the second section being located over the predetermined areas of the polymer coating on the outer surface of the container so that a seal is formed when the lid and coatings are heated. Also claimed is a container/lid assembly comprising a peripheral flange.
Patent FI-965205-A0 (FI)
Inventor: DALEY LEIGH BRIAN
IPC: C21D1/26
Filed: 1996-12-23
Abstract: PCT No. PCT/AU95/00378 Sec. 371 Date Dec. 26, 1996 Sec. 102(e) Date Dec. 26, 1996 PCT Filed Jun. 27, 1995 PCT Pub. No. WO96/00305 PCT Pub. Date Jan. 4, 1996Yield strength of a cold rolled steel section is increased and controlled by performing a predetermined amount of strain by way of cold working in an in-line roll forming process followed by a controlled amount of strain aging wherein the temperature of the steel section is elevated to a point below 500 DEG  C. and held at an elevated temperature for a time up to 30 seconds. The heating typically takes place by induction heaters (16) and the time aging may be provided in an in-line galvanizing bath (17) before cooling the steel in a quench bath (18). The effect is further enhanced by further cold working and the consequent additional strain in forming rolls (19). For a given steel composition the degree of yield enhancement can be controlled by the temperature and tie parameters and also by the degree of initial roll forming in shaping rolls (10).
Patent IL-80675-A0 (IL)
Title: Method of producing a random faded effect on cloth or garments,and the product obtained thereby
IPC: D06L3/08
Filed: 1986-11-18
Abstract: of the DISCLOSURE In the method disclosed, cloth to be faded is brought into dry contact with pumice granules that are impregnated with a chemical bleaching agent such as a hypochlorite; the action takes place in a conventional process machine, the drum of which is rotated for a preset duration.
Patent AU-PP797598-A0 (AU)
Title: Therapeutic agent
IPC: A23K20/158
Filed: 1998-12-30
Abstract: Biologically active extracts of celery seed are produced by controlled ethanolic extraction, distillation and drying, and further processing by supercritical fluid extractions (SFE), and may be further fractionated by column fractionation, distillation, LiAlH reduction and the like. These extracts possess activity for the treatment and prevention of acute and chronic pain, inflammation and gastrointestinal irritation.
Patent AU-PQ776800-A0 (AU)
Title: Detection method and reagents
IPC: G01N33/84
Filed: 2000-05-26
Abstract: A method of detecting soluble lithium in a liquid biological sample comprising combining: (a) an amount of the biological sample; (b) 2,3,7,8,12,13,17,18-octobromo-5,10,15,20-tetrakis(4-sulphonatophenyl) porphyrin; (c) alkali; (d) detergent; (e) chelating agent; and (f) optionally a suitable solvent; to produce a test sample; detecting absorbance change of the test sample relative to a lithium deficient standard sample at a wavelength of between about 475 nm and about 485 nm, between about 515 nm and about 525 nm or simultaneously between about 475 nm and about 485 nm and between about 515 nm and about 525 nm, wherein absorbance change indicates presence of soluble lithium in the biological sample. Also disclosed is a method of quantitatively measuring soluble lithium ions in a biological sample and a reagent for use in such methods.
Patent IL-101014-A0 (IL)
Title: 4-pyrimidinone derivatives,their preparation and their application in therapy
IPC: C07D239/52
Filed: 1992-02-19
Abstract: 1. Compounds, existing in three tautomeric forms, corresponding to the general formulae (I), (I') and (I'') <IMAGE>  in which   R1 = linear or branched (C1-7)alkyl, linear or branched (C3-9)alkenyl, cyclo(C3-7)alkyl(C1-6)alkyl, R2 = H, linear or branched (C1-7)alkyl, cyclo(C3-7)alkyl(C1-3)alkyl, aryl(C1-3)alkyl optionally substituted in the ring, aryloxy(C1-3)alkyl optionally substituted in the ring, arylthio(C1-3)alkyl optionally substituted in the ring, arylsulphonyl(C1-3)alkyl optionally substituted in the ring, heteroaryl(C1-3)alkyl optionally substituted in the ring, R3 = CO2H 1H-tetrazol-5-yl, NHCOR11, NHSO2R11, CONHSO2R11, CONHOR12, where R11 = CH3, CF3 or optionally substituted phenyl, R12 = H, CH3 or optionally substituted phenyl, as well as their pharmaceutically acceptable organic or inorganic salts. Therapeutic application.t
Patent IL-103852-A0 (IL)
Title: Method and kit for the detection of antibodies in seronegative individuals
IPC: G01N33/53
Filed: 1992-11-24
Abstract: The present invention relates to an improved method and kit for the detection of antibodies directed against the human immunodeficiency virus (HIV) in whole blood obtained from individuals who are HIV-seronegative as determined by conventional assay techniques. Whole blood is isolated from these individuals and cultured directly with mitogen to stimulate the proliferation of B-lymphocytes producing immunoglobulin specific for HIV. This method provides a rapid, simple, and inexpensive means for screening large numbers of blood samples for HIV infection while minimizing exposure of the technician to infectious blood components.
Patent IL-103960-A0 (IL)
Title: Improved electrochemiluminescent label for dna probe assays
IPC: C07H21/00
Filed: 1992-12-03
Abstract: This invention relates to a new electrochemiluminescent (ECL) label for oligonucleotides using phosphoramidite chemistry.
Patent IL-110732-A0 (IL)
Title: Apparatus for monitoring multiple nucleic acid amplifications simultaneously
IPC: C12M1/00
Filed: 1994-08-22
Abstract: An apparatus for monitoring multiple nucleic acid amplifications simultaneously. In order to provide real-time monitoring of the amplification product of multiple nucleic acid amplifications simultaneously the apparatus is characterized in that it comprises a thermal cycler (12) including a heat conducting member having multiple recesses formed therein; and a sensor (16a) arranged for detecting light emitted from said recesses, simultaneously. <IMAGE>
Patent IL-126803-A0 (IL)
Title: Method and composition for reconforming multi-epitopic antigens to initiate an immune response
IPC: A61P37/04
Filed: 1998-10-29
Abstract: Disclosed are methods for treating cancer comprising administering a xenotypic antibody and a chemotherapeutic drug to a patient suffering from cancer. Also disclosed is a method for inducing a host immune response in a patient against a multi-epitopic in vivo tumor antigen present in the host serum, which antigen does not elicit an effective host immune response, comprising administering to the patient a chemotherapeutic drug and a composition comprising a binding agent that specifically binds to a first epitope on the antigen and allowing the binding agent to form a binding agent/antigen pair, wherein an effective host immune response is elicited against a second epitope on the antigen.
Patent IL-130178-A0 (IL)
Title: Highly absorbent composite and method of making the same
IPC: B29C70/34
Filed: 1997-12-15
Abstract: Composite compositions containing, as the major components, fine hydratable microfibril fibers obtained from cellulose or derivatives thereof and a solid capable of swelling with water, wherein at least part of the surface of the solid is coated with the fine microfibril fibers, and a process for producing the same. The solid capable of swelling with water is exemplified by particulate polymer absorbents to which short fibers have been added as the third component. These composite absorbents may be located on supporting sheets made of, for example, a nonwoven fabric to give composite absorbent sheets applicable to various absorbent products including diapers for infants and adults.
Patent IL-131589-A0 (IL)
Title: Apparatus for inducing forces by fluid injection
IPC: F16C32/06
Filed: 1999-08-25
Abstract: An injection system used to generate an acrodynamically induced force, with accordance to the present invention, serving as an air-cushion non-contact supporting system. The system comprises a high pressure manifold (101), connected by high pressure pipe (103), to a high pressure source (102). A SASO-conduit (1), whose inlet (2) is connected to the high pressure manifold, and the outlet (3) is located on the injection-surface (104), of the injection system.
Patent IL-135370-A0 (IL)
Title: Panel for raised floors
IPC: E04F15/024
Filed: 1998-10-01
Abstract: A panel for raised floors, which comprises: a box-like element made of metallic material, which forms a bottom and side walls with first edges which are folded outwards and is meant to contain a body made of filler material; and a covering element. The covering element also is made of metallic material, is flat, is larger than the dimensions of the box-like element and has second edges which are folded a first time around the first edges of the box-like element. The first and second edges of the box-like element and, respectively, of the covering element are folded together a second time along the side walls, so as to be arranged laterally thereto in order to reduce the dimensions of the panel and increase its loading strength along its sides.
Patent IL-138284-A0 (IL)
Title: Acylbenzoxazines for enhancing synaptic response(s)
IPC: A61P25/24
Filed: 1999-04-02
Abstract: Compounds based on the benzoxazine ring system that are remarkably more potent than corresponding benzoyl piperidines for enhancing synaptic responses mediated by AMPA receptors are disclosed, as are methods for the preparation thereof, and methods for their use for treatment of subjects suffering from impaired nervous or intellectual functioning due to deficiencies in the number of excitatory synapses or in the number of AMPA receptors. The invention compounds can also be used for the treatment of non-impaired subjects for enhancing performance in sensory-motor and cognitive tasks which depend on brain networks utilizing AMPA receptors and for improving memory encoding.
Patent IL-150353-A0 (IL)
Title: Dual-release compositions of a cyclooxygenase-2 inhibitor
IPC: A61P43/00
Filed: 2000-12-20
Abstract: Pharmaceutical compositions are provided comprising one or more orally deliverable dose units, each comprising a selective cyclooxygenase-2 inhibitory drug of low water solubility, for example celecoxib, in an immediate-release fraction and a controlled-release, slow-release, programmed-release, timed-release, pulse-release, sustained-release or extended-release fraction. The compositions are useful in treatment or prophylaxis of cyclooxygenase-2 mediated conditions and disorders.
Patent IL-150733-A0 (IL)
Title: Daptomycin, pharmaceutical compositions containing the same and methods for the preparation thereof
IPC: C07K1/34
Filed: 2001-01-18
Abstract: The invention discloses highly purified daptomycin and to pharmaceutical compositions comprising this compound. The invention discloses a method of purifying daptomycin comprising the sequential steps of anion exchange chromatography, hydrophobic interaction chromatography and anion exchange chromatography. The invention also discloses a method of purifying daptomycin by modified buffer enhanced anion exchange chromatography. The invention also discloses an improved method for producing daptomycin by fermentation of  Streptomyces roseosporus.  The invention also discloses high pressure liquid chromatography methods for analysis of daptomycin purity. The invention also discloses lipopeptide micelles and methods of making the micelles. The invention also discloses methods of using lipopeptide micelles for purifying lipopeptide antibiotics, such as daptomycin. The invention also discloses using lipopeptide micelles therapeutically.