baber/WOPTO huggingface dataset:
Patent CA-2563087-A1 (CA)
Inventor: REUBINOFF BENJAMIN
IPC: C40B30/04
Filed: 2005-04-08
Abstract: This invention relates generally to the production of human neuronal cells from human embryonic stem cells and/or human neuronal progenitor cells. In some embodiments, the human neuronal cells are neural crest cells. In other embodiments, the human neuronal cells are peripheral neurons. In other embodiments, the human neuronal cells are schwann cells. The invention provides methods of culturing and purifying human neuronal cells and uses thereof. Such uses include generating models of neuropathy, drug screening methods, and cell based therapeutic.
Patent CA-2564757-A1 (CA)
Inventor: INAKOSHI MASATOSHI
IPC: C07D453/02
Filed: 2005-04-25
Abstract: A novel process for producing solifenacin or its salt that is useful as a medicine, especially a therapeutic agent and/or preventive agent for urinary diseases, such as frequent urination and involuntary urination. In particular, there are provided (1) a process for producing solifenacin from 2-(imidazolylcarbonyl)-1-phenyltetrahydroisoquinoline as a production starting material; (2) a process for producing solifenacin succinate from quinuclidinyl (1RS)-phenyltetrahydroisoquinolinecarboxylate as a production starting material; (3) a process for producing solifenacin from a lower-alkylquinuclidinyl carbonate as a production starting material; and (4) a process for producing solifenacin, comprising causing an alkali metal lower alkoxide to act on a secondary lower alkyl or tertiary lower alkyl phenyltetrahydroisoquinolinecarboxylate as a production starting material.
Patent CA-2565071-A1 (CA)
Inventor: STAPLETON TERRY M
IPC: G01J1/58
Filed: 2005-05-03
Abstract: A temperature sensor that has a thermally conducting contact with a surface that emits electromagnetic radiation in proportion to the temperature of the contact is disclosed. The sensor has a resilient member attached to the contact and configured to extend the contact toward the object to be measured.  A first light waveguide is attached to the contact and is configured to transmit the electromagnetic radiation from the contact. The sensor has a guide with a bore formed therein that the first waveguide is insertable into.  When the contact is moved, the first waveguide moves within the bore. A second waveguide is attached to the guide such that a variable gap is formed between the ends of the first waveguide and the second waveguide. Electromagnetic energy from the first waveguide traverses the gap and can be transmitted by the second waveguide. The guide allows the first waveguide to move with the contact in order to ensure that the contact is fully engaged with the surface of the object.
Patent CA-2566164-A1 (CA)
Inventor: SATCHELL DONALD PRENTICE JR
IPC: C10G47/34
Filed: 2006-10-30
Abstract: A process derived hydrogen donor solvent is used to increase the maximum resid conversion and conversion rate in an ebullated bed resid hydrocracker.  The hydrogen donor solvent precursor is produced by hydroreforming reactions within the resid hydrocracker, recovered as the resin fraction from a solvent deasphalting unit, regenerated in a separate hydrotreater reactor, and recycled to the ebullated bed resid hydrocracker. The major advantage of this invention relative to earlier processes is that hydrogen is more efficiently transferred to the resin residual oil in the separate hydrotreater and the hydrogen donor solvent effectively retards the formation of coke precursors at higher ebullated bed resid hydrocracker operating temperatures and resid cracking rates.
Patent CA-2568659-A1 (CA)
Inventor: WOOD THOMAS D
IPC: E21B15/00
Filed: 2006-11-22
Abstract: A rig 10 for selectively inserting coiled tubing or threaded tubulars into a well includes a mast 14 extending upward from a mast carrier 12, and a coiled tubing injector 16 and a coiled tubing reel 26 supported on a coiled tubing carrier 28 separate from the mast carrier. The mast 14 may be pivotal on the mast carrier to attach the coiled tubing injector 16 to the mast while the injector is supported on the coiled tubing carrier.
Patent CA-2569133-A1 (CA)
Title: Tire assembly with high elongation cable belt
Inventor: REITER LEONARD JAMES
IPC: B32B5/08
Filed: 2006-11-28
Abstract: A high elongation cable and a tire having a tread belt with an extensible reinforcing cable is provided. The high elongation cable has a 3×7×m or a 4×7×m construction, wherein m is comprised of at least two layers, wherein the outermost layer is comprised of a plurality of twisted filaments, said filaments having a diameter d, wherein the spacing between said twisted filaments is less than the diameter d.
Patent CA-2569405-A1 (CA)
Inventor: GALLIHER PARRISH
IPC: B01F33/40
Filed: 2005-06-06
Abstract: Accordingly, in one embodiment of the invention, a bioreactor system is presented and includes a disposable container for housing biomaterials for processing, the disposable container including at least one input port, at least one exhaust port, at least one harvest port, and the integrity of the sterile environment is protected with sterile filters attached to all external open ports a structure for supporting the disposable container, one or more sensors for sensing one or more parameters of the biomaterials in the container, a heater for heating the contents of the container, the heater having a thermostat and mixing system arranged with the system such that biomaterials contained in the disposable container are mixed.
Patent CA-2570316-A1 (CA)
Title: Epithelial delaminating device
Inventor: PEREZ EDWARD
IPC: A61F9/013
Filed: 2005-06-16
Abstract: The described device is useful in the field of ophthalmology. The devices and methods for using it involve separating or lifting corneal epithelium from the eye in a substantially continuous layer to form a flap or pocket. In particular, the devices generally utilize a non-cutting, oscillating separator or dissector that is configured to separate the epithelium at naturally occurring cleavage surfaces in the eye, particularly between the epithelium and the corneal stroma (Bowman's membrane), specifically separating in the region of the lamina lucida, the separator or dissector having a structure that oscillates at that cleavage surface interface during the dissection step.  The separated epithelium may se lifted or peeled from the surface of the eye to form an epithelial flap or pocket. The epithelium may then be replaced on the cornea after a refractive procedure or placement of an ocular lens on the eye.
Patent CA-2572176-A1 (CA)
Title: Probe optimization methods
Inventor: MCCORMICK MARK
IPC: C12P19/34
Filed: 2005-06-21
Abstract: The present invention provides methods for optimizing nucleic acid detection assays for use in basic research and clinical research. Specifically, the invention provides a method for empirically optimizing nucleic acid probes by testing them with samples containing genomic DNA with variations in copy number in different regions of the genome. The invention enables the optimization of probes for any hybridization based assay including microarrays, bead-based assays, genotyping assays and RNAi assays.
Patent CA-2573431-A1 (CA)
Title: Ultrasonic transducer having a digital interface
Inventor: DUNBAR LEE
IPC: H04R1/40
Filed: 2007-01-09
Abstract: Systems and methods which partition ultrasound signal processing between an ultrasound system main processing unit and transducer assembly are shown. A    particular division of signal processing functionality disposed in the main processing unit and the transducer assembly may be selected to provide a desired weight balance, a desired level of processing for data communication between the main processing unit and the transducer assembly, etcetera. Battery capacity may additionally or alternatively be partitioned between the main processing unit and the transducer assembly.
Patent CA-2576401-A1 (CA)
Inventor: MARRY GARY ROBIN
IPC: B05B15/00
Filed: 2000-07-25
Abstract: A hand held spray spout (10) has a basket filter (26) seated against an anti-siphon valve (24) proximate the base end of a water passage (12) within the spout. The filter has a plurality of protrusions (50) mounted within the inner diameter of the valve (24) and is also biased against the rim (52) of the valve. The filter has prongs (56) extending upstream from the basket section (40) to abut and be biased by a supply hose end which is mounted to the base end (14) of the hand held spray spout (10).
Patent CA-2578278-A1 (CA)
Title: Granulate-matrix for bone repair and/or augmentation
Inventor: FEHR DANIEL
IPC: A61K6/891
Filed: 2007-02-12
Abstract: The present invention relates to a composition comprising a granulate selected from the group consisting of autogenous bone material, bone/bone like material from natural sources, synthetic materials and mixtures thereof and a matrix obtainable by a self selective reaction of at least two precursors A and B in the presence of water. A  kit for preparing said composition is also described.
Patent CA-2578743-A1 (CA)
Inventor: ZABLOCKI JEFF
IPC: A61K31/7008
Filed: 2005-08-30
Abstract: Disclosed are syntheses suitable for large scale manufacture of novel compounds that are partial and full A1 adenosine receptor agonists, useful for treating various disease states, in particular tachycardia and atrial flutter, angina, and myocardial infarction.
Patent CA-2579310-A1 (CA)
Title: Process for isomerization of alpha olefins to internal olefins
Inventor: ZHANG JIAN JIAN
IPC: C08K3/34
Filed: 2005-10-17
Abstract: The present invention relates to embodiments for a process for the isomerization of at least one alpha olefin to an internal olefin via a multi-step process resulting in a mixture comprising alkene isomers and a low level of oligomers. According to the present invention an alkylaluminum compound is used in combination with the Group VIII transition metal salt for interaction with the latter, and thereby generating catalytically active species for the isomerization of 1 -alkenes to internal alkenes, wherein this mixture is subsequently combined with an acid washed clay.
Patent CA-2582669-A1 (CA)
Inventor: CASPER ROBERT F
IPC: A61K31/56
Filed: 2005-10-04
Abstract: Following a diagnosis of ectopic pregnancy, at least one aromatase inhibitor, is administered to a patient, either alone or in combination with other aromatase inhibitors or therapeutic agents or as an adjuvant to conservative surgical treatment, such as laparoscopy, to prevent the establishment and/or continuation of the ectopic pregnancy. In certain preferred embodiments, the aromatase inhibitor is administered in conjunction with methotrexate.
Patent CA-2592097-A1 (CA)
Title: Device and use thereof
Inventor: ORWAR OWE
IPC: B03C11/00
Filed: 2005-12-23
Abstract: Disclosed herein is a device comprising at least one supporting solid surface comprising at least one membraneophilic region; a covering layer that is at least partially immobilized to the membraneophilic region, said covering layer consisting of (i) a surfactant membrane, (ii) a lipid mimicking polymer, (iii) a surfactant or emulsion system or (iv) a liquid crystal; and a substance included in or bound to, connected to or associated with the covering layer.  Also disclosed are methods wherein the device is used and use of the device.
Patent CA-2592449-A1 (CA)
Title: Recombinant microorganisms for increased production of organic acids
Inventor: YI JIAN
IPC: C12N1/21
Filed: 2005-12-16
Abstract: Disclosed are recombinant microorganisms for producing organic acids. The recombinant microorganisms express a polypeptide that has the enzymatic activity of an enzyme that is utilized in the pentose phosphate cycle. The recombinant microorganism may include recombinant Actinobacillus succinogenes that has been transformed to express a Zwischenferment (Zwf ) gene. The recombinant microorganisms may be useful in fermentation processes for producing organic acids such as succinic acid and lactic acid. Also disclosed are novel plasmids that are useful for transforming microorganisms to produce recombinant microorganisms that express enzymes such as Zwf.
Patent CA-2593216-A1 (CA)
Title: Pressure guide for pcb
Inventor: PAPE GUENTER
IPC: H01R12/18
Filed: 2007-07-06
Abstract: The invention proposes a pressure guide for an electric connection between contact decks on a circuit board (1) and electric contacts arranged in an edge connector (6), wherein said pressing device aligns a circuit board (1) guided between two guide bars (10, 11) by means of a spring element (16, 26) arranged in the one of the guide bars, namely in such a way that the electric strip conductors applied on the circuit board exactly conform to the contacts arranged within the edge connector.
Patent CA-2595874-A1 (CA)
Inventor: ZHANG XIAOZHI
IPC: C12N15/31
Filed: 2005-01-26
Abstract: A recombined adenovirus p53 antagonizing the certain toxic side effects such as those caused by anti - tumor chemotherapy and radiotherapy. A single recombined adenovirus p53 can also enhance the body's function of tumor patient, including biochemical index, such as promote hemogram, liver function, kidney function and the like, and improve living quality, such as increase appetite, ameliorate mental status.
Patent CA-2596192-A1 (CA)
Inventor: PILZ GEORG
IPC: H01H9/56
Filed: 2006-01-17
Abstract: The invention relates to a method and device for determining a switching time of an electric switching device. An electric switching device comprises an interrupter link (1). A first line section (2) and a second line section (3) can be connected and disconnected by means of said interrupter link (1). In order to determine a switching time, the temporal progression of a driving voltage (A) is determined in the first line section (2). In addition, a temporal course of an oscillator voltage (B, B1) appearing in the second line section (2) is determined. Potential switching times are determined at the voltage zero crossings of a resulting voltage (C, C1). The selection of the potential switching times ensues while evaluating the rises of the driving voltage (A, A1) and of the oscillator voltage (B, B1) or of the polarity of the oscillating current (D).
Patent CA-2596336-A1 (CA)
Title: Mini-channel heat exchanger with reduced dimension header
Inventor: VERMA PARMESH
IPC: F28F9/04
Filed: 2005-12-28
Abstract: A heat exchanger includes a plurality of flat, multi-channel heat exchange tubes extending between spaced headers. Each heat exchange tube has its inlet end in fluid flow communication to an inlet header through a transition connector. The transition connector has a body defining a divergent flow path extending from an inlet opening in its inlet end to an outlet opening in its outlet end, and a tubular nipple extending outwardly from the inlet end of the divergent flow path through the wall of the inlet header. The tubular nipple defines a fluid flow path extending between the inlet end of the divergent flow path of the transition connector and the fluid chamber of the inlet header. The inlet header has a lateral dimension less then the lateral dimension of the heat exchange tube.
Patent CA-2597052-A1 (CA)
Inventor: KAJUCH PETE
IPC: F16K31/60
Filed: 2006-02-03
Abstract: A fluid control valve includes flexible coupling (18) between a handle (12) and a valve stem which allows the components of the assembly on one side of a wall (31) to be angularly misaligned with the components on the opposing side.  Because the components adjacent to the room side of the wall can be mounted perpendicular to the wall, a decorative escutcheon (22) can be mounted flush against the mounting wall when the wall or the valve is out of plumb.
Patent CA-2602275-A1 (CA)
Inventor: SCHAEPER GEORG
IPC: C10L1/224
Filed: 2006-03-23
Abstract: The invention relates to using detergent additives for reducing a particle amount in the exhaust gas of direct injection diesel engines, in particular, in diesel engines provided a common rail injection system.
Patent CA-2602835-A1 (CA)
Inventor: MAYER ESTHER
IPC: A61N5/06
Filed: 2006-03-30
Abstract: A device (10) is presented for use in treatment of tissues inside a body cavity. The device comprises a probe member (12) having at least a portion thereof carrying a plurality of light sources (18), at least said portion of the probe member (10) having dimensions and shape suitable for insertion into a certain body cavity and for arranging within the surface thereof a three-dimensional array of said light sources, the light sources being configured and operable to irradiate optical energy outwardly from said probe member.
Patent CA-2603014-A1 (CA)
Title: Massaging apparatus
Inventor: YANG TSUNG-HSUN
IPC: A61H39/04
Filed: 2007-09-18
Abstract: A massaging apparatus includes a control unit for controlling first to third drive units so as to drive movement of a second guiding rail unit along a first guiding rail unit in a transverse direction, movement of a mounting seat on the second guiding rail unit in a longitudinal direction, and movement of a post on the mounting seat in a vertical direction such that a massage member mounted on a bottom end of the post is moved to contact a user's body that lies on a bed body at a desired acupuncture point. Thereafter, the control unit further controls the third drive unit so as to drive further downward movement of the post corresponding to a desired massage pressure, and controls the first and second drive units so as to drive movement of the massage member around the desired acupuncture point of the user' s body.
Patent CA-2604845-A1 (CA)
Inventor: MCHUGH SEAN
IPC: G01N33/53
Filed: 2006-04-14
Abstract: Methods and systems for rapidly determining the level of platelet inhibition in whole blood, due to aspirin usage, with a single use arachidonic based assay device that can be stored at room temperature is provided. A lyophilized assay reagent that contains arachidonic acid at sufficient concentration to maximally activate platelets is utilized. An antioxidant within the same lyophilized assay reagent reduces the oxidation rate of arachidonic acid but does not interfere with platelet function. An oxygen absorber within the single use assay device packaging creates an inert environment within a short period of time after package is sealed. The assay device can have a housing with a plurality of channels and a common blood sample introduction port coupled to each of a channel of the plurality of channels. The assay device can also include a lyophilized assay reagent that contains arachidonic acid at sufficient concentration to maximally activate platelets.
Patent CA-2605367-A1 (CA)
Title: Method for recovering solvents
Inventor: RUSZKAY JUDE T
IPC: C08F6/00
Filed: 2006-04-07
Abstract: A method for recovering a solvent from its mixture containing oligomers extracted from grafted polyolefins is disclosed. The method comprises distilling the solvent from the mixture in the presence of a naphthalene compound. The method of the invention significantly increases the solvent recovering yield without causing the vessel fouling.
Patent CA-2606318-A1 (CA)
Title: Paillettes pour applications cachees de securite
Inventor: COOMBS PAUL G
IPC: B42D25/36
Filed: 2004-08-11
Abstract: Des paillettes cachées portant un ou plusieurs symboles ou présentant une forme sélectionnée sont utilisées dans une composition, telle qu'une encre ou une peinture, afin de conférer une caractéristique cachée de sécurité à un objet. Selon certains modes de réalisation, la composition comprend un pigment de base et les paillettes cachées sont des paillettes cachées de pigment dont les caractéristiques visuelles correspondent à celles du pigment de base. Selon d'autres modes de réalisation, des paillettes cachées transparentes ou opaques sont mélangées avec un pigment de base dans un agent véhiculeur. Selon encore d'autres modes de réalisation, des paillettes cachées transparentes ou opaques sont mélangées avec un vernis de base afin de former une composition transparente qui peut être appliquée sur une caractéristique de sécurité existante ou ailleurs. La composition est utilisée pour imprimer un champ sur l'objet, par exemple un certificat d'actions ou un billet de banque. Les paillettes cachées ne sont pas facilement détectées par une observation causale sous la lumière visible. Selon un certain mode de réalisation, les paillettes cachées deviennent fluorescentes lorsque la caractéristique cachée de sécurité est éclairée par une lumière ultraviolette, permettant à l'observateur de déterminer la position de la paillette cachée et d'observer les indices cachés. Selon un mode de réalisation particulier, une paillette cachée portant un ou plusieurs symboles est localisée par rayonnement non visible, puis observée sous la lumière visible afin de lire le(s) symbole(s) sur la paillette cachée.
Patent CA-2607181-A1 (CA)
Title: A non-surgical method for preventing or reducing the rate of the progression of non-proliferative diabetic retinopathy and the treatment of other ocular conditions
Inventor: LEVY BRIAN
IPC: C12N9/68
Filed: 2006-05-10
Abstract: A non-surgical method for preventing or reducing the rate of the progression of non-proliferative diabetic retinopathy to the proliferative form of diabetic retinopathy comprising intravitreally administering to a patient suffering from non-proliferative diabetic retinopathy an effective amount of serine proteinase enzyme sufficient to create, without surgery, a posterior vitreal detachment to prevent or reduce the progression of proliferative diabetic retinopathy in said patient. Also disclosed is a non-surgical method of treating ocular conditions such as retinal ischemia, retinal inflammation, retinal edema tractional retinal detachment, tractional retinopathy, vitreous hemorrhage and tractional maculopathy by intravitreally administering to a patient suffering from one or more of these conditions with an effective amount of a serine proteinase enzyme to reduce or treat that particular ocular condition. Plasmin, microplasmin and miniplasmin are preferred serine proteinase enzymes and plasmin is the most preferred.
Patent CA-2610303-A1 (CA)
Title: Breech loader packaging apparatus and associated devices, methods, systems and computer program products
Inventor: MAY DENNIS J
IPC: B65B9/15
Filed: 2006-05-30
Abstract: Systems for enclosing at least one target product in a covering material, include an elongate product chute (30) having an outer surface and opposing receiving and discharge end portions with an interior cavity extending therethrough and an elongate breech loading chute (50) alignably positioned generally above the product chute (30), the elongate loading chute (50) configured to direct at least one target product into the product chute (30).
Patent CA-2611563-A1 (CA)
Title: An oral device and kit for use in association therewith
Inventor: SMITH REBECCA C
IPC: A61C17/022
Filed: 2006-04-24
Abstract: An oral device for use with a person in which at least one non-toxic gas pulse is delivered to a predetermined location in the mouth via a device conduit.  The oral device may be provided as a kit with at least one device for measuring the subject~s responses and representing them as feedback to the subject/clinician. A method of creating a gas bolus pulse train, delivering it to a predetermined mouth area, and monitoring the subject~s responses to it, is also shown. The oral device and method may be used as a diagnostic tool, or a therapeutic tool, in swallowing or speech rehabilitation of children and adults who have swallowing, speech, salivary, and/or oral sensorimotor impairments.