baber/WOPTO huggingface dataset:
Patent DE-60222804-D1 (DE)
Inventor: DRYSDALE MARTIN JAMES
IPC: C07D409/04
Filed: 2002-12-19
Granted: 2007-11-15
Abstract: The present invention pertains to the use of certain 3,4-diarylpyrazoles of formula (I), both in vitro and in vivo, to inhibit heat shock protein 90 (HSP90), and in the treatment of conditions mediated by HSP90, including, for example, cancer; wherein: Ar<SUP>3 </SUP>is independently: a C<SUB>5-20</SUB>aryl group, and is optionally substituted; Ar<SUP>4 </SUP>is independently: a C<SUB>5-20</SUB>aryl group, and is optionally substituted; R<SUP>5 </SUP>is independently: hydrogen; halo; hydroxy; ether; formyl; acyl; carboxy; ester, acyloxy; oxycarbonyloxy; amido; acylamido; aminocarbonyloxy; tetrazolyl; amino; nitro; cyano; azido; sulfhydryl; thioether; sulfonamido; C<SUB>1-7</SUB>alkyl; C<SUB>3-20</SUB>heterocycyl; or C<SUB>5-20</SUB>aryl; R<SP>N</SP> is independently: -H; C<SUB>1-7</SUB>alkyl; C<SUB>3-20</SUB>heterocycyl; or, C<SUB>5-20</SUB>aryl; and pharmaceutically acceptable salts, solvates, amides, esters, ethers, chemically protected forms, and prodrugs thereof. The present invention also pertains to such compounds, pharmaceutical compositions comprising such compounds, such compounds for medical use, such compounds for use in the treatment of conditions mediated by HSP90, including, for example, cancer, and use of such compounds in the preparation of medicaments for such treatments.
Patent DE-60233978-D1 (DE)
Inventor: RAJALA JUSSI
IPC: H04W28/12
Filed: 2002-10-16
Granted: 2009-11-19
Abstract: A method for use in handing over user equipment from a source cell to a target cell in a cellular communications network. The cellular communications system comprises a plurality of control units. When handing over from a source cell to a target cell in a cellular communications network comprising a plurality of control units, the user equipment determines if the source cell and target cell in a communications system are controlled by the same control unit.
Patent DE-60234498-D1 (DE)
Inventor: SOFTLEY ANDREW JOHN KENNETH
IPC: H02G3/12
Filed: 2002-04-19
Granted: 2010-01-07
Abstract: The present invention provides an accessory mounting for use in service distribution ducting. In order to allow it to be used in service distribution ducting of different depths and with accessories of different depths, the depth of the accessory mounting 1 is variable. To achieve this, there is first mounting part 2 which has an open top and an open bottom 5. A second mounting part 3, having an open top 18 is slidably received inside the opening 5. The position of the first mounting part 2 with respect to second mounting part 3 is variable by means of ratchet surfaces 16,17,24 and 25. <??>The accessory mounting 1 can be engaged with an accessory by way of screw post 10, 11 and it can be engaged with service distribution ducting by way of engagement means 14, 15. <??>The invention also extends to a method of manufacturing an accessory mounting according to the invention, service distribution ducting comprising an accessory mounting according to the invention and components for manufacturing the accessory mounting of the invention. <IMAGE>
Patent DE-60235544-D1 (DE)
Inventor: ETZLER FRANK M
IPC: A61K31/439
Filed: 2002-06-11
Granted: 2010-04-15
Abstract: An insufflation for the administration of a drug into a body cavity is described where the carrier for the drug is a finely divided powder selected from the group consisting of myoinositol, mannitol and cellobiose.
Patent DE-60237400-D1 (DE)
Inventor: PATEL BIPIN C M
IPC: A61K41/00
Filed: 2002-12-24
Granted: 2010-09-30
Abstract: Neutron capture therapy (NCT) for example, Boron neutron capture therapy (BNCT) requires the delivery of a neutron capture element such as Boron to a target site to be treated, followed by irradiation with neutrons. The invention provides new means for delivery of the neutron capture element in the form of insoluble inorganic nanoparticles having a particle size of about 10<SUP>-10 </SUP>m to about 10<SUP>-6</SUP>m. The neutron capture element can be in particulate form or in the form of glass or glass ceramic or as a polymerised inorganic matrix or as a sol-gel derived xerogel. The nanoparticles of the invention can further comprise a biocompatible outer layer which provides the function of stealth and assists in providing an appropriate clearance rate. In some embodiments, the nanoparticles comprise a core selected from, for example, mica, zeolites, TiO<SUB>2 </SUB>spheres, ZrO<SUB>2 </SUB>spheres or particles or organic polymer particles or spheres surrounded by a thin film of the neutron capture element. Pharmaceutical compositions, uses and methods for the treatment of cancer are disclosed. Also disclosed is a process for the preparation of water insoluble nanoparticles comprising causing friction between pure blocks of the required neutron capture element in an inorganic form and collecting nanoparticles that result therefrom.
Patent DE-60237560-D1 (DE)
Inventor: YOSHIE TORU
IPC: B27F7/00
Filed: 2002-11-29
Granted: 2010-10-14
Abstract: An electric stapler is provided with: a stapler; a transversely moving mechanism for traveling the stapler along a transverse rail; a driver (504) arranged at a front portion of the stapler; a staple cartridge charging port provided at a rear face of the stapler; and a rotating mechanism for horizontally rotating the stapler by 90 degrees. 
The staple cartridge charging port at the rear face of the stapler is directed in a direction of an extended line of the transverse rail by traveling the stapler to one end portion of the transverse rail and rotating the stapler horizontally by 90 degrees.
Patent DE-60306350-D1 (DE)
Inventor: LAVI JOSEF
IPC: A47J27/12
Filed: 2003-03-27
Granted: 2006-08-03
Abstract: A deep-frying appliance and method utilizing a receptacle (10) having a lower electrical heater body (20), an upper electrical heater body (30) movable between an inoperative position allowing food entry and removal and an operative position above the lower heater body (20), to accelerate heating of the oil. A food article holder (40) can be supported above the oil to preheat food items, or immersed in the oil for cooking.
Patent DE-60306585-D1 (DE)
Inventor: OGGIONI IVANO
IPC: A47C19/00
Filed: 2003-06-16
Granted: 2006-08-17
Abstract: A container bed with means for moving the mattress frame, comprising a container body (2) to which at least one mattress frame (3) is connected, the container bed further comprising, on each side wall of the container body (2), means for tilting (10,11) the mattress frame (3) which act between the mattress frame and a side bar (20) that is pivoted to the side wall, the rotation fulcrum (30) of the side bar being arranged in a point (30) that substantially provides balancing, with respect to the fulcrum (30), of the weights that bear on the fulcrum for rotation of the side bar (20) with respect to the fulcrum, by means of a force that can be applied by mere manual action, in order to arrange the mattress frame (3) in a substantially horizontal position that is raised with respect to the container body (2). <IMAGE>
Patent DE-60308641-D1 (DE)
Inventor: KWON OH-KYONG
IPC: H05B33/00
Filed: 2003-11-13
Granted: 2006-11-09
Abstract: A light emitting display for compensating for the threshold voltage of transistor or mobility and fully charging a data line. A transistor and first through third switches are formed on a pixel circuit of an organic EL display. The transistor supplies a driving current for emitting an organic EL element (OLED). The first switch diode-connects the transistor. A first storage unit stores a first voltage corresponding to a threshold voltage of the transistor. A second switch transmits a data current in response to a select signal. A second storage unit stores a second voltage corresponding to the data current. A third switch transmits the driving current to the OLED. A third voltage determined by coupling of the first and second storage units is applied to a transistor to supply the driving current to the OLED. <IMAGE>
Patent DE-60311955-D1 (DE)
Inventor: STRATICO GIANFRANCO
IPC: H02K15/08
Filed: 2003-12-09
Granted: 2007-04-05
Abstract: The present invention concerns forming wire coils by simultaneously winding a plurality of wires onto a dynamo-electric machine component. In order to maximize the amount of wire that can be placed in the spacings of the dynamo-electric machine component, the turns of the wire coil must be regularly disposed without twisting the plurality of wires onto each other. Current winding apparatus may allow certain portions of the wire turns to unevenly accumulate and locally bulge outward from the collection of wire coils. Such bulges, especially in consideration of the limited spacings available on an dynamo-electric machine component, may interfere with or access to the spacings by a wire dispensing member during the winding process. The present invention proposes to perform multiple-wire winding processes that avoid wire twisting and improper disposition of the wires. Further, the present invention proposes to improve the ability of the wire dispensing member to traverse the spacings on the component. As a consequence, the winding processes performed with the present invention are less likely to be hindered by interference and are capable of obtaining more wire fill within the component spacings and higher winding speeds. <IMAGE>
Patent DE-60312011-D1 (DE)
Inventor: D AMICO DANIEL
IPC: C11C5/00
Filed: 2003-08-12
Granted: 2007-04-05
Abstract: Disclosed is a fragranced wax candle and fragranced wax composition comprising paraffin wax, a fragrance containing an antioxidant, with or without vegetable wax and/or beeswax, saturated fatty acid, hindered amine, and an additive. Also disclosed is a method for incorporating an antioxidant into the fragranced candle wax composition.
Patent DE-60312390-D1 (DE)
Inventor: LAU ANTHONY P
IPC: G06Q10/10
Filed: 2003-05-06
Granted: 2007-04-19
Abstract: A mobile device that uses events as triggers for reminders in addition to date and time. Such events may be location-based, or based on other events or tasks scheduled by the user and other events or tasks scheduled by another user. <IMAGE>
Patent DE-60313945-D1 (DE)
Inventor: PESTRYAKOV ALEXANDER
IPC: H04B1/40
Filed: 2003-03-11
Granted: 2007-07-05
Abstract: The present invention generally relates to the field of multi-band phase-locked loop (PLL) frequency synthesizer architectures (200) with an improved phase noise performance, that can advantageously be applied to wireless multi-mode transceivers in a cellular communication system based on the UMTS and on the GSM/GPRS standard. It particularly refers to a multi-band PLL frequency synthesizer (200) comprising three PLL frequency synthesizer subunits (202, 203, 204) used for generating carrier signals (co1,i(t), co2,j(t), co3,l(t), co4,l(t)) with frequencies (fo1,fo2,fo3,fo4) suitable for UMTS and GSM/GPRS frequency bands, especially to an extension of the PLL frequency synthesizer architecture of a conventional quad-band transceiver (200) providing additional carrier signals (co5,k(t)) with appropriate carrier frequencies (fo5,k) for the GSM/GPRS 850 MHz frequency band <??>Moreover, a multi-mode PLL frequency synthesizer (200) of a wireless multi-mode transceiver is proposed, which comprises a reference frequency source (201) providing an oscillator signal (sr(t)) with a constant reference frequency (fr), a first frequency synthesizer subunit (202) for converting said signal (sr(t)) into carrier signals (co1,i(t)) with frequencies (fo1,i) in the range of a first frequency band (UMTS TDD1+2 Tx/Rx, UMTS FDD Tx), a second frequency synthesizer subunit (203) for transforming the oscillator signal (sr(t)) into carrier signals (co2,j(t)) having frequencies (fo2,j) in the range of a second frequency band (UMTS FDD Rx), and a third frequency synthesizer subunit (204) for converting the oscillator signal (sr(t)) into an auxiliary signal (sa(t)) with a fixed frequency (fa). Said auxiliary signal (sa(t)) is used together with the carrier signals (co2,j(t)) of said second frequency band (UMTS FDD Rx) to generate carrier signals (co3,l(t), co4,l(t)) with frequencies (fo3,l, fo4,l) in the range of a third (GSM/GPRS (DCS) 1,800 MHz Tx/Rx, GSM/GPRS (PCS) 1,900 MHz Tx/Rx) and fourth frequency band (GSM/GPRS 900 MHz Tx/Rx, and GSM/GPRS 850 MHz Rx). A frequency divider (241) derives a signal (co5(t)) in the range of a fifth frequency band (GSM/GPRS 850 MHz Tx) from further intermediate frequency signals (s11,k(t)) supplied by the third frequency synthesizer subunit (204) by dividing the frequency (fa) of the auxiliary signal (sa(t)) by an integer value (M12). <IMAGE>
Patent DE-60314377-D1 (DE)
Inventor: FABIAN HEINZ
IPC: G02B6/00
Filed: 2003-03-06
Granted: 2007-07-26
Abstract: In the known method for producing an optical fiber, a coaxial arrangement comprising a core rod and an outer jacket tube is elongated, the coaxial arrangement being supplied in a vertical orientation to a heating zone and being softened therein zonewise, starting with the lower end thereof, and the optical fiber being withdraw downwards from the softened portion, whereby an annular gap existing between core rod and jacket tube is collapsed. Starting therefrom, in order to provided a method which makes it possible to produce optical fibers with a minimum curl and at low costs, the invention suggests that a quartz glass cylinder treated mechanically to its final dimension and having an outer diameter of at least 100 mm should be used as the jacket tube. An optical fiber obtained according to the method is characterized in that without the action of external forces it assumes a radius of curvature of at least 6 mm.
Patent DE-60316150-D1 (DE)
Inventor: CHAN SELENA
IPC: G01N33/543
Filed: 2003-05-16
Granted: 2007-10-18
Abstract: The methods and apparatus 300 disclosed herein concern Raman spectroscopy using metal coated nanocrystalline porous silicon substrates 240, 340 . In certain embodiments of the invention, porous silicon substrates 110, 210 may be formed by anodic etching in dilute hydrofluoric acid 150 . A thin coating of a Raman active metal, such as gold or silver, may be coated onto the porous silicon 110, 210 by cathodic electromigration or any known technique. The metal-coated substrate 240, 340 provides an extensive, metal rich environment for SERS, SERRS, hyper-Raman and/or CARS Raman spectroscopy. In certain embodiments of the invention, metal nanoparticles may be added to the metal-coated substrate 240, 340 to further enhance the Raman signals. Raman spectroscopy may be used to detect, identify and/or quantify a wide variety of analytes, using the disclosed methods and apparatus 300.
Patent DE-60316608-D1 (DE)
Inventor: TAOKA NORIYUKI
IPC: B01D46/00
Filed: 2003-03-17
Granted: 2007-11-08
Abstract: A ceramic filter assembly integrated by adhering together a plurality of columnar honeycomb filters made of a porous ceramic sintered material with a ceramic sealing material layer and having a generally elliptical cross sectional shape when cut parallel to end faces of the plurality of honeycomb filters, the ceramic filter assembly characterized in that when a hypothetical first straight line intersects the generally elliptical contour at two points in which the distance therebetween is maximum and a hypothetical second straight line orthogonal to the first straight line intersects the generally elliptical contour at two points in which the distance therebetween is minimum, the number of sealing material layers the first straight line of the assembly traverses is less than or equal to the number of sealing material layers the second straight line traverses.
Patent DE-60318018-D1 (DE)
Inventor: NISHI KENGO
IPC: F02F7/00
Filed: 2003-01-17
Granted: 2008-01-24
Abstract: To form a dividing portion 21 of an outer ring 13 so that a dividing line is of a crankshaft shape as seen in the axial direction while first and second race ring halves 16, 17 fit to each other. The dividing portion 21 is formed so that first dividing surfaces located on the side of the inside cylindrical surface 14 are in contact with each other in the state of being attached to a cylinder body and a crankcase. The dividing portion 21 is also formed so that a clearance S is produced between third dividing surfaces on radially outer side. <IMAGE>
Patent DE-60318115-D1 (DE)
Inventor: CONTI UGO
IPC: B63B35/42
Filed: 2003-02-25
Granted: 2008-01-24
Abstract: The vessel has a pair of flexible hulls flexibly coupled to a "cabin" between and above the hulls, thereby allowing the hulls to independently follow the surface of the water. Motor pods are hinged to the back of the hulls to maintain the propulsion system in the water, even if the stern of one or both hulls tends to lift out of the water when crossing swells and the like. Various other embodiments and features are disclosed.
Patent DE-60324549-D1 (DE)
Inventor: DESALVO CHRISTOPHER JOSEPH
IPC: H04L12/58
Filed: 2003-04-25
Granted: 2008-12-18
Abstract: A method is described comprising: receiving an e-mail containing an original attachment at a data service, the e-mail addressed to a data processing device to which the data service is communicatively coupled, the data processing device having specified processing capabilities; converting the original attachment based on the specified processing capabilities to a format which the data processing device can process; receiving an e-mail response from the data processing device intended to include the original attachment; locating and reattaching the original attachment; and transmitting the e-mail message with the original attachment to its destination.
Patent DE-60329739-D1 (DE)
Inventor: BRORSON MICHAEL
IPC: C01G47/00
Filed: 2003-08-06
Granted: 2009-12-03
Abstract: Rhenium(IV) sulphide (ReS2) nanotube material comprising hollow cylinders of concentric rhenium(IV) sulphide layers, the ReS2 interlayer distance being 0.5-0.7 nm each ReS2 layer consisting of a layer of rhenium atoms sandwiched between two layers of sulphur atoms. <??>The invention also concerns a method of preparation of the rhenium(IV) sulphide nanotube material.
Patent DE-60330356-D1 (DE)
Title: Stickstoff-lost-derivaten
Inventor: SPRINGER C J
IPC: C07C275/32
Filed: 2003-09-01
Granted: 2010-01-14
Abstract: This invention pertains to certain enzyme (CPG2) activated self-immolative nitrogen mustard prodrugs, which are useful in enzyme prodrug therapy (EPT), such as ADEPT and GDEPT, for the treatment of proliferative conditions, such as cancer, and which have the following formula: wherein: R<SUP>N </SUP>is independently C<SUB>1-7</SUB>alkyl; X<SUP>1 </SUP>is independently -I, -Br, or -Cl; X<SUP>2 </SUP>is independently -I, -Br, or -Cl; the group -N(CH<SUB>2</SUB>CH<SUB>2</SUB>X<SUP>1</SUP>)(CH<SUB>2</SUB>CH<SUB>2</SUB>X<SUP>2</SUP>) is independently attached at the 2-position or at the 4-position; each R<SUP>G </SUP>is independently -H or an ester substituent; n is independently an integer from 0 to 4; each R<SUP>P</SUP>, if present, is independently a phenyl substituent; m is independently an integer from 0 to 4; each R<SUP>M</SUP>, if present, is independently a mustard substituent; and pharmaceutically acceptable salts, solvates, amides, and esters thereof. The present invention also pertains to pharmaceutical compositions comprising such compounds; such compounds and compositions for use in methods of treatment of the human or animal body by therapy; the use of such compounds and compositions for the manufacture of medicaments for the treatment of proliferative conditions; and the like.
Patent DE-60330505-D1 (DE)
Inventor: KANAOKA SHIGERU
IPC: C12Q1/68
Filed: 2003-09-19
Granted: 2010-01-21
Abstract: It is intended to provide a non-invasive and convenient method of detecting a tumor marker for diagnosing colon cancer which is superior in sensitivity and specificity to the existing fecal occult blood test. More specifically speaking, a method of detecting a tumor marker for diagnosing colon cancer which comprises collecting biological sample which is immediately frozen using liquid nitrogen in some cases, homogenizing the sample in the presence of an inhibitor of an RNA digesting enzyme to give a suspension, extracting RNA from the obtained suspension, subjecting the extracted RNA to reverse transcription to give cDNA. amplifying the obtained cDNA and then detecting the thus amplified cDNA. This method is characterized by involving no procedure of separating cell components from the biological sample.
Patent DE-60335553-D1 (DE)
Inventor: KATZE MICHAEL
IPC: G01N33/574
Filed: 2003-07-03
Granted: 2011-02-10
Abstract: Methods for the diagnosis of hepatocellular carcinoma (HCC) are set forth. Improved assay methods and scanning methods are included that employ non-cell-associated and cell-associated HCC related proteins. Such methods are based upon the discovery of genes that were up-regulated in diseased versus normal tissue as well as in HCC tissue when compared to the tissue of patients with other ailments.
Patent DE-60336357-D1 (DE)
Inventor: MORANDOTTI ROBERTO
IPC: B41J2/175
Filed: 2003-05-19
Granted: 2011-04-21
Abstract: The ink jet printer comprises a printhead movable in front of a printing medium and provided with an ink cartridge integral with it; the cartridge is filled with ink from a main, high capacity tank, which is connected at intervals to the cartridge by means of a capillary element. During each connection, the capillary element is brought into contact with the sponge inside the cartridge, while a peristaltic pump mounted integral upon the main tank provides a pressure suitable for generating a sufficient flow of ink to refill the cartridge in a short time frame. To perform the refilling, the cartridge is brought at the end of its stroke into a service station mounted on the body of the main tank, which is moved against the cartridge by means of a motor-driven linkage, controlled by a refilling management programme, in response to the signals of a cartridge ink level sensor.
Patent DE-60336901-D1 (DE)
Inventor: MARTIN RICHARD
IPC: C07D413/12
Filed: 2003-03-04
Granted: 2011-06-09
Abstract: Compounds, pharmaceutical compositions and methods for modulating the activity of nuclear receptors are provided. In particular, quinazolinones are provided for modulating the activity of farnesoid X receptor (FXR) and/or orphan nuclear receptors.
Patent DE-68900693-D1 (DE)
Inventor: STUETTGEN G PROF DR MED
IPC: A61K47/12
Filed: 1989-02-18
Granted: 1992-02-27
Abstract: Pharmaceutical composition for the transdermal application of heparin, characterized in that the preparation in addition to the active agent contains a salt of choline and a fatty acid having 12 to 20 carbon atoms in the alkyl group besides usual carrier and addition products of an ointment base.
Patent DE-68903605-D1 (DE)
Inventor: FRANCE GORDON
IPC: A61K9/20
Filed: 1989-04-27
Granted: 1993-01-07
Abstract: A pharmaceutical chewable tablet composition comprising:     (i) granules containing a therapeutically active substance; and (ii) an extragranular water-insoluble hygroscopic excipient in an amount of 5% to 15% by weight of the total weight of the tablet. Particular therapeutically active substances include cimetidine and examples of suitable hygroscopic excipients include microcrystalline cellulose and powdered cellulose.
Patent DE-68904010-D1 (DE)
Inventor: HILAIRE GERARD MICHEL
IPC: B65G13/071
Filed: 1989-06-14
Granted: 1993-02-04
Abstract: a) The invention relates to a curved form element for a transfer line, in particular for combination with a band, chain, belt, runner or roller conveyor, which element comprises a chassis equipped with rolling members (runners, rollers), b) this element is characterised in that at least certain rolling members (11, 12) are integral with a radial shaft (10) carrying integrally in rotation a driving runner (13) which rolls in order to be driven in rotation against a drive disc (8,15) placed in the curve of the element. c) The invention is applicable to curved form elements for a transfer line. <IMAGE>