baber/WOPTO huggingface dataset:
Patent EP-3995771-A1 (EP)
Inventor: GARCÍA MONTERO ANDRÉS CELESTINO
IPC: F26B5/06
Filed: 2020-07-02
Abstract: The invention relates to a device and method for the simultaneous lyophilisation of a plurality of biological samples ensuring the traceability of said samples intended to be housed within coded containers (1); the device comprises a diffuser block (2) comprising a plurality of openings which define receptacles (21) to house the coded containers (1), wherein the diffuser block (2) further comprises a perimeter cavity (24) configured so that the alloy surrounding each receptacle (21) is similar in all the coded containers (1), enabling high thermal homogeneity, and the receptacles (21) have through openings defining an open bottom (23) to scan the coded containers (1). Likewise, the device further comprises a transfer lid (3) to ensure the position of each container (1) when it is transferred to the diffuser block (1) and back to the starting box (4).
Patent EP-4000223-A1 (EP)
Title: Support of virtual network and non-virtual network connectivity on the same virtual machine
Inventor: TANEJA VISHAL
IPC: H04L12/46
Filed: 2020-06-03
Abstract: A hybrid state for a virtual machine (VM) in a cloud computing system enables a VM to communicate with other VMs that belong to a virtual network (VNET VMs) while maintaining connectivity with other VMs that do not belong to the virtual network (non-VNET VMs). A non-VNET VM can be transitioned to a hybrid VM that operates in a hybrid state. The hybrid VM can be assigned a private virtual IP address (VNET address) for communication with other VNET VMs. The hybrid VM can continue to use a physical IP address to communicate with other non-VNET VMs. In this way, the hybrid VM is able to maintain connectivity with other non-VNET VMs during and after migration to the VNET. A network stack can be configured to process data packets that are destined for non-VNET VMs differently from data packets that are destined for VNET VMs.
Patent EP-3932429-A1 (EP)
Inventor: MURAO HIDETOSHI
IPC: A61P43/00
Filed: 2020-02-27
Abstract: An object of the present invention is to provide a combination medicine that exhibits a practical curing effect on a tumor such as acute myeloid leukemia. According to the present invention, there is provided a combination medicine, which contains a compound represented by General Formula [1] specified in the present specification, such as (S,E)-N-(1-((5-(2-((4-cyanophenyl)amino)-4-(propylamino)pyrimidin-5-yl)-4-pentyn-1-yl)ami no)-1-oxopropan-2-yl)-4-(dimethylamino)-N-methyl-2-butenamide or a salt thereof, and at least one selected from the group consisting of a BCL-2 inhibitor and a pyrimidine antimetabolite.
Patent EP-3935036-A1 (EP)
Title: Compositions vétérinaires et procédés d'utilisation associés
Inventor: SMITH COLLEEN
IPC: C07C37/14
Filed: 2020-03-04
Abstract: La présente invention concerne des compositions vétérinaires comprenant de l'acide hyaluronique ayant un poids moléculaire d'au moins 800000 Daltons et du cannabidiol, des compositions vétérinaires comprenant de l'acide hyaluronique ayant un poids moléculaire d'au moins 800000 Daltons et un complexe de cannabidiol, et des méthodes de traitement de maladies et/ou de symptômes desdites affections chez des sujets non humains en ayant besoin par administration d'une quantité efficace de telles compositions.
Patent EP-3925582-A1 (EP)
Inventor: OOTSUKI TOMOYUKI
IPC: A61B3/13
Filed: 2020-02-27
Abstract: A surgical microscope system according to an embodiment of the present technology a microscope optical system, an imaging device, and an image processing device. The imaging device captures an image of a visual field range including an eye to be treated through the microscope optical system. The image processing device magnifies a first region in an image including the eye to be treated based on the image captured by the imaging device and reduces a second region other than the first region in the image to be capable of being displayed in a region other than a magnified region that is the first region magnified in the image.
Patent EP-3939704-A1 (EP)
Inventor: KANESHIMA KEINOSUKE
IPC: A23L15/00
Filed: 2020-03-10
Abstract: Provided is a method that enables sufficient separation of an egg shell and an egg shell membrane from each other even in a small scale, using a simpler configuration than conventional methods. The method for separating an egg shell and an egg shell membrane from each other includes a step of adding an egg shell with an egg shell membrane attached thereto to a swirling flow of an alkaline solution.
Patent EP-3936520-A1 (EP)
Inventor: LI YI
IPC: C12N15/63
Filed: 2020-03-06
Abstract: Provided in the present invention is a T-cell receptor (TCR) having the characteristic of binding a FMNKFIYEI-HLA A0201 complex. The binding affinity of the TCR to the FMNKFIYEI-HLA A0201 complex is at least 5 times that of the wild-type TCR to the FMNKFIYEI-HLA A0201 complex. Further provided in the present invention is a fusion molecule of the TCR with a therapeutic agent. The TCR may be used alone or in combination with the therapeutic agent, so as to target a tumor cell presenting the FMNKFIYEI-HLA A0201 complex.
Patent EP-4028664-A1 (EP)
Title: Unité de pompe à chambre de moteur conique
Inventor: WIGGEMANS JOHNNY ANTONIUS JACOBUS
IPC: F04B1/10
Filed: 2020-09-11
Abstract: L'invention concerne une unité de pompe (10) comprenant une pompe hydraulique à entraînement électrique (4) destinée à mettre sous pression un système d'actionnement hydraulique. L'unité de pompe (10) comprend une pompe hydraulique (4) dans une chambre de pompe (110) d'un carter de pompe (11). La pompe (4) est entraînée par un moteur électrique (3) qui comprend un corps (310) de rotor de moteur et un ensemble de bobines de champ (32) et d'aimants (33). Un espace libre (C) est disposé autour du corps (310) de rotor de moteur qui est divergent dans la direction axiale d'un petit diamètre à un grand diamètre, de telle sorte qu'une rotation du corps (310) de rotor de moteur amène un fluide hydraulique à s'écouler à force vers le plus grand diamètre. La sortie de fluide (122) au niveau du plus grand diamètre de l'espace libre permet une sortie du fluide hydraulique, de telle sorte qu'un écoulement de fluide soit généré, ce qui réduit le frottement hydraulique à l'intérieur de l'unité de pompe pour entraîner une augmentation de la capacité de la pompe.
Patent EP-3938364-A1 (EP)
Inventor: BOND SILAS
IPC: A61K31/437
Filed: 2020-03-13
Abstract: The present invention provides compounds that modulate biological metals and to pharmaceutical compositions containing such compounds. The invention particularly relates to imidazo[1,5- a ]pyridine compounds that modulate iron and are useful for the treatment of diseases, particularly neurological diseases such as Parkinson's disease (PD), Alzheimer's 5 disease (AD), Alzheimer-type dementia, Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and multiple system atrophy (MSA).
Patent EP-3946579-A1 (EP)
Inventor: BOCIAN DARIN
IPC: A61N5/067
Filed: 2020-03-26
Abstract: Systems and methods for treating fibrous masses associated with conditions such as Morton's neuroma, stump neuroma, plantar fibroma, plantar fibromatosis, plantar fasciitis, plantar fasciopathy, and Achilles tendinopathy. According to implementation herein, exemplary methods may comprise non-surgically delivering electromagnetic energy to such fibrous masses in various ways.
Patent EP-4038866-A1 (EP)
Title: Method for addressing a terminal
Inventor: SCHMITZ STEFAN
IPC: H04L29/12
Filed: 2020-09-24
Abstract: The present invention relates to a method for addressing a terminal (e.g. 1-1), preferably a meter, of a group of terminals (1-1, 1-M), in which a primary wireless communication channel (4) is provided between a gateway (e.g. 2-1) and the respective terminal (e.g. 1-1), assigned to the gateway (e.g. 2-1), of a wireless communication system, preferably a wireless MBus communication system, wherein, in order to improve the primary communication, the gateway (2-1, 2-N) is assigned a sub-network (6-1, 6-N) which is formed of the gateway (2-1, 2-N) in question and at least one terminal (e.g. 1-1), preferably a group of terminals (1-1, 1-M), a terminal network address (7-1, 7-M) is generated for each terminal (1-1, 1-M) assigned to the gateway (2-1, 2-N) of the sub-network (e.g. 6-1, 6-N), and the terminal network address (7-1, 7-M) is used to transfer data in the primary communication channel (4) between the gateway (2-1, 2-N) and terminals (1-1, 1-M) assigned to the gateway.
Patent EP-3950020-A1 (EP)
Inventor: IKEDA TAKUJI
IPC: A61L101/36
Filed: 2020-02-26
Abstract: A decontamination device according to an aspect of the present invention is configured to decontaminate an air filter for particle removal. This decontamination device is configured to release gas containing peracetic acid such that the gas reaches the air filter and not release mist containing peracetic acid. A system according to another aspect of the present invention includes a container and a decontamination device. The container is configured to hold an air filter for particle removal. The decontamination device is configured to release gas containing peracetic acid into the container such that the gas reaches the air filter and not release mist containing peracetic acid.
Patent EP-3947650-A1 (EP)
Inventor: PARK DONG SHIN
IPC: C12N5/0786
Filed: 2020-03-30
Abstract: The present invention relates to a method for generating a microglia-sufficient brain organoid comprising the step of incubating primitive-like macrophage cells with a brain organoid that is between about 15 to about 30 days old in cerebral organoid medium comprising CSF-1 in a low attachment cell culture vessel to generate microglia cells. The present invention also relates to a microglia-sufficient brain organoid obtained by the method as described herein.
Patent EP-4031682-A1 (EP)
Inventor: SEGALE DARREN
IPC: C12Q1/6816
Filed: 2020-09-18
Abstract: Some embodiments provided herein include methods and compositions for the detection of target ligands on an array. In some embodiments, a capture probe specifically binds to a target ligand from a sample, the location of a bead comprising the capture probe in an array is determined, and the bead is decoded to identify the capture probe and the sample. In some embodiments, a barcode is indicative of a capture probe attached to a bead; and an index is indicative of a subpopulation of beads. Some embodiments relate to sequencing target polynucleotides from several different nucleic acids samples on a bead array.
Patent EP-4091574-A1 (EP)
Inventor: LEE IN WHAN
IPC: G01B17/00
Filed: 2020-09-28
Abstract: Disclosed is a digital measurement apparatus including a mounting part on which a measurement object is placed; and a measuring part for measuring the length of the measurement object and providing the measurement value of the measured measurement object as a reference value for adjusting the length of a new measurement object, wherein the measuring part measures the length of the measurement object using any one selected from among a moving method of converting a distance moved due to interference with the measurement object placed on the mounting part; a radiation method of radiating a measurement signal toward the measurement object and converting information of the detected measurement signal into the length of the measurement object; and a scanning method of scanning the measurement object. With this configuration, accuracy in measuring the length of a measurement object may be improved using a simple structure.
Patent EP-4062047-A1 (EP)
Inventor: MATTES ANDREAS
IPC: F02M59/46
Filed: 2020-10-19
Abstract: Kraftstoff-Hochdruckpumpe für ein Kraftstoffsystem einer Brennkraftmaschine, mit einem Pumpengehäuse, einem in dem Pumpengehäuse angeordneten Auslass-Rückschlagventil (20), wobei das Auslass-Rückschlagventil (20) ein Ventilsitzelement (30), ein Ventilelement (32), ein Anschlagelement (34) für das Ventilelement (32) und eine Mehrzahl von sich in einer axialen Richtung erstreckenden und in Umfangsrichtung gesehen voneinander beabstandeten Führungsstegen (56) umfasst, die das Ventilelement (32) in radialer Richtung führen und die entweder einstückig mit dem Ventilsitzelement (30) oder einstückig mit dem Anschlagelement (34) ausgebildet sind, dadurch gekennzeichnet, dass benachbarte Führungsstege (56) am vom Ventilsitzelement (30) oder vom Anschlagelement (34) abragenden Ende durch einen Verbindungsabschnitt (60) miteinander verbunden sind.
Patent EP-4048188-A1 (EP)
Inventor: WANG TIANYI
IPC: H05B47/105
Filed: 2020-10-20
Abstract: The present invention relates to a tooth whitening system (10), comprising a light source (30), a light detector (40), and a processing unit (50). The light source is configured such that a wavelength of the light emitted is adjustable over a wavelength range of operation. The detector is configured to detect light emitted from the light source. The processing unit is configured to control the light source to adjust the wavelength of the light emitted by the light source and determine a measure of absorption light detected that was emitted from the light source as the wavelength is adjusted. The processing unit is configured to utilize the determined measure of absorption to operate the light source at a wavelength at a peak in absorption.
Patent EP-3962651-A1 (EP)
Title: Microfluidic devices and methods of making the same
Inventor: PAOLINI RICHARD J JR
IPC: B01L3/00
Filed: 2020-04-22
Abstract: A microfluidic device including: (a) top plate, including: a top substrate; a first layer of hydrophobic material coupled to a surface of the top substrate; a continuous electrode between the first layer of hydrophobic material and the top substrate; (b) a bottom plate, comprising: a bottom substrate; a plurality of electrodes coupled to the bottom substrate; a second layer of hydrophobic material coupled to the second substrate and atop the plurality of electrodes. The top and bottom plate are placed in a spaced relationship, thereby defining a gap between the first and second layers of hydrophobic material to permit droplet motion within the gap under application of propulsion voltages. At least one of the top substrate, the first layer of hydrophobic material, the second layer of hydrophobic material, the bottom substrate, and the plurality of electrodes have a non-uniform thickness, and the gap has a plurality of heights.
Patent EP-3932336-A1 (EP)
Inventor: ZHANG JIN
IPC: A61B17/12
Filed: 2020-04-28
Abstract: An occluder (1) with no externally protruding structure at either end, comprising a mesh body (10); a first closing line (20), the first closing line (20) passing through a plurality of grids formed by mesh at a first closing end (11) in order to implement closing of the first closing end (11); and a second closing line (30), the second closing line (30) passing through a plurality of grids formed by mesh at a second closing end (12) in order to implement closing of the second closing end (12). Compared to occluders in the prior art with a threaded connecting member, the present solution can reduce the manufacturing difficulty, reduce the reject rate, and save costs.
Patent EP-4041381-A1 (EP)
Inventor: NIKINMAA SAKARI
IPC: A61N5/06
Filed: 2020-10-12
Abstract: L'invention concerne un embout buccal et un procédé de traitement antibactérien de surfaces intra-buccales. L'embout buccal comprend un corps fait d'un matériau thermoconducteur, ce corps comprenant des surfaces externes faciale et linguale et des surfaces internes faciale et linguale, inclinées, conçues pour faire face respectivement aux surfaces faciale et linguale de dents. Une source de lumière est fixée à la surface inclinée du corps et conçue pour délivrer de la lumière sur des surfaces de dents, la source de lumière étant positionnée sur au moins une desdites surfaces externes et conçue pour délivrer ladite lumière par l'intermédiaire desdites surfaces internes à la fois aux surfaces faciale et linguale des dents.
Patent EP-4241306-A1 (EP)
Title: Power field-effect transistor and manufacturing method
Inventor: WIRTHS STEPHAN
IPC: H01L29/06
Filed: 2020-11-04
Abstract: In one embodiment, the power field-effect transistor (1) comprises: at least two source regions (21) at a top side (20) of a semiconductor body (2); a drain region (22) at a back side (23) of the semiconductor body (2); at least two charge barrier regions (24) in the semiconductor body (2) so that electrically between each one of the source regions (21) and the drain region (22) there is one of the charge barrier regions (24); and a gate electrode (3) located in a trench (4) in the semiconductor body (2), and the charge barrier regions (24) are located adjacent to the trench (4), wherein, next to the trench (4) and seen in a first plane (A) perpendicular with the top side (21) and a main elongation direction (L) of the trench (4), the top side (21) is formed only by the source regions (21).
Patent EP-4041914-A1 (EP)
Inventor: SURKOV KIRILL
IPC: C12Q1/6804
Filed: 2020-10-02
Abstract: L'invention concerne des procédés de détection de sensiblement tous les types d'ADN acellulaire (cfDNA) dans des échantillons biologiques, comprenant de l'ADN acellulaire lié à un nucléosome, de l'ADN acellulaire lié à un exosome et de l'ADN acellulaire non lié (y compris de l'ADN double brin (ADNdb), un ADN simple brin (ADNsb) et des oligonucléotides), pour le diagnostic, la surveillance et le traitement de maladies provoquées par des taux accrus d'ADN acellulaire, ou leur étant corrélées. Le procédé est basé sur l'isolement d'ADN acellulaire à partir d'échantillons de fluide corporel par mise en contact du fluide corporel avec un agent d'affinité n comprenant une histone de liaison, par exemple h1-3.
Patent EP-4059275-A1 (EP)
Inventor: ZHOU YAN
IPC: H04W52/24
Filed: 2020-10-15
Abstract: The present disclosure provides for identifying, based on downlink control information (DCI), a physical uplink shared channel (PUSCH) transmission associated with a network entity, determining that a dedicated physical uplink control channel (PUCCH) resource is not configured for uplink transmission to the network entity, determining a default spatial relation reference signal for the PUSCH transmission based on determining that the PUCCH resource is not configured, and performing the PUSCH transmission based on the default spatial relation reference signal.
Patent EP-4077188-A1 (EP)
Inventor: ROUSSEL FRANK OLIVIER
IPC: B66B5/00
Filed: 2020-11-30
Abstract: Die Erfindung betrifft eine Steuervorrichtung (200) zum Steuern einer Aufzugsanlage (100) in einem Inspektionsbetrieb, wobei die Aufzugsanlage (100) einen Sicherheitskreis (206) mit mindestens einem im Inspektionsbetrieb geöffneten Sicherheitskontakt (204) und einen Inspektionspfad (202) zum Überbrücken des mindestens einen Sicherheitskontakts (204) aufweist. Die Steuervorrichtung (200) umfasstein erstes Bedienelement (PB1) zum Bedienen der Aufzugsanlage (100) im Inspektionsbetrieb, ein zweites Bedienelement (PB2) zum Bedienen der Aufzugsanlage (100) im Inspektionsbetrieb, eine erste Schalteinheit (K1), die einen ersten Kontakt (K1-3) und ein erstes Verzögerungsglied (C1) aufweist und ausgeführt ist, um den ersten Kontakt (K1-3) als Reaktion auf ein Betätigen des ersten Bedienelements (PB1) zu schliessen und als Reaktion auf ein Loslassen des ersten Bedienelements (PB1) zu öffnen, und eine mit der ersten Schalteinheit (K1) parallel geschaltete zweite Schalteinheit (K2), die einen zweiten Kontakt (K2-3) und ein zweites Verzögerungsglied (C2) aufweist und ausgeführt ist, um den zweiten Kontakt (K2-3) als Reaktion auf ein Betätigen des zweiten Bedienelements (PB2) zu schliessen und als Reaktion auf ein Loslassen des zweiten Bedienelements (PB2) zu öffnen. Der erste Kontakt (K1-3) und der zweite Kontakt (K2-3) sind in dem Inspektionspfad (202) in Reihe geschaltet. Das erste Verzögerungsglied (C1) ist ausgeführt, um ein Öffnen des ersten Kontakts (K1-3) um eine definierte erste Verzögerungszeit ab dem Loslassen des ersten Bedienelements (PB1) zu verzögern. Das zweite Verzögerungsglied (C2) ist ausgeführt, um ein Öffnen des zweiten Kontakts (K2-3) um eine definierte zweite Verzögerungszeit ab dem Loslassen des zweiten Bedienelements (PB2) zu verzögern.
Patent EP-3978546-A1 (EP)
Title: Surface treating agent
Inventor: MARUHASHI KAZUKI
IPC: C09D7/61
Filed: 2020-05-14
Abstract: 1. A surface-treating agent comprising at least one fluoropolyether group-containing compound of the following formula (1) or (2) a chlorine ion, wherein a chlorine ion concentration in the surface-treating agent is 0.1 ppm by mass or more and 1.0 ppm by mass or less. 
 
        R F1   α  - X A  - R Si   β      (1) 
 
        R Si   γ  - X A  - R F2 - X A  - R Si   γ      (2)
Patent EP-3977827-A1 (EP)
Title: Chassis panel with selectable cable management insert and cabling method therefore
Inventor: SCHOENFELDER RODNEY C
IPC: H05K7/14
Filed: 2020-05-20
Abstract: A chassis panel defines one or more rearward-facing, open-ended slots at a rear of the chassis panel. One or more management inserts can be mounted within the open-ended slot along a forward-rearward axis. Cables can be pre-cabled through the inserts prior to being installed at one or more port modules. Accordingly, the port modules can be cabled prior to being installed at the chassis panel without first having to thread the cables through the chassis panel. Alternatively, the cables can be slid directly into the open- ended slots during installation of the port modules.
Patent EP-4073606-A1 (EP)
Inventor: VAN LOON BART
IPC: G05B19/418
Filed: 2020-12-08
Abstract: The disclosure relates to a system (10) for monitoring and/or controlling one or more chemical plant(s) (12), wherein the system (10) comprises a first processing layer (14) associated with the chemical plant (12) and communicatively coupled to a second processing layer (16), wherein the first processing layer (14) and the second processing layer (16) are configured in a secure network (18, 20), wherein the first processing layer (14) provides process or asset specific data (22) of the chemical plant (12) to the second processing layer (16), wherein the second processing layer (16) is configured to contextualize process or asset specific data to generate plant specific data and to provide plant specific data (24) of one or more chemical plant(s) (12) to an interface (26) to an external network.
Patent EP-3976754-A1 (EP)
Title: Uses of patient-derived intestinal organoids for celiac disease diagnosis, screening and treatment
Inventor: KUO CALVIN J
IPC: C12M1/00
Filed: 2020-06-03
Abstract: Air-liquid interface organoid cultures are initiated from human small intestine biopsy tissue comprising both the syngeneic intestinal epithelium and native intestinal immune cells, without reconstitution, which may be obtained from an individual pre-disposed or suffering from celiac disease. The organoid cultures exhibit T cell activation in response to in vitro gluten challenge and provide tools for a novel diagnostic method for celiac disease. Diagnosis may comprise the addition of immunogenic gluten-derived peptides into the organoid cultures, and assessing hallmarks of active celiac disease, including without limitation: 1) gliadin-presentation, resulting T-cell responses, such as 2) expansion and 3) activation, 4) epithelial-cell death and consequent 5) increased proliferative epithelial cell responses to gliadin. Celiac patients, either in GRD or GFD, test positive for these tests. In other embodiments the organoids are used to test responses to candidate therapeutic agents, assessing reduction of gliadin-dependent (1) T cell activation or expansion, or (2) organoid epithelial cell death.