baber/WOPTO huggingface dataset:
Patent WO-2019165707-A1 (WO)
Inventor: SUN YAZHOU
IPC: H04L29/08
Filed: 2018-05-11
Abstract: The present application relates to a file sharing method, a computer device and a storage medium. The method comprises: receiving a first encrypted file transmission request; acquiring a second user public key, and generating a temporary symmetric encryption key; acquiring a first encrypted file; obtaining an original file according to a first user symmetric key, and using the temporary symmetric encryption key to encrypt the original file so as to obtain a second encrypted file; using the second user public key to obtain an encrypted key file; sending the first encrypted file transmission request to a terminal corresponding to a second user, and receiving a second user symmetric key returned by the terminal according to the first encrypted file transmission request; acquiring a second user private key according to the second user public key, and obtaining the temporary symmetric encryption key according to the second user private key; and obtaining the original file according to the temporary symmetric encryption key, obtaining a third encryption file according to the second user symmetric key, and transmitting the third encryption file to the terminal corresponding to the second user.
Patent WO-2018214973-A1 (WO)
Inventor: LI LIN
IPC: H01M10/0565
Filed: 2018-05-25
Abstract: 本发明公开了一种可凝胶化体系及在锂空气电池、有机体系的超级电容器或电容电池中的应用。所述有机体系的超级电容器或电容电池包括凝胶电解质和/或固态电解质，其由可凝胶化体系制备得到的，所述可凝胶化体系包括如下组分，(a)锂盐，(b)醚类化合物；所述用于锂空气电池的可凝胶化体系还包括(c)用于锂空气电池的电解液或其溶剂；体系中可凝胶化的聚合物和/或可凝胶化的预聚物的质量百分含量小于等于1wt％；通过调节所述体系中各组分含量和种类，可以制备得到强度可调、形成时间可调、转变温度可调，同时也具有可逆性的凝胶和/或固态电解质；所述制备方法简单、反应条件温和、反应周期短、产物收率高、制备成本低、易于实现工业化生产。
Patent WO-2019227426-A1 (WO)
Title: Multimedia data processing method and apparatus, and device/terminal/server
Inventor: HU YUEPENG
IPC: H04L29/06
Filed: 2018-05-31
Abstract: The embodiments of the present application provide a multimedia data processing method and apparatus, and a device/terminal/server. The multimedia data processing method comprises: a first user terminal obtains multimedia content shared by a second user terminal; performs target detection on the multimedia content to obtain a target detection result, wherein the target detection comprises performing template information detection on the multimedia content; and generates an augmented reality (AR) object according to the target detection result and an image acquired by the first user terminal, and displays the AR object. By means of the embodiments of the present application, interaction between users can be performed effectively, and the interaction effect is improved.
Patent WO-2019091102-A1 (WO)
Title: 脱敏规则配置方法、程序、应用服务器及计算机可读存储介质
Inventor: PENG JIE
IPC: G06F21/62
Filed: 2018-06-03
Abstract: 本申请公开了一种脱敏规则配置方法，所述方法包括：预先建立敏感字段、规则类型与用户权限的映射关系表；进入脱敏规则参数配置页面，选择数据查询子系统；依据所述映射关系表对不同的用户权限选择不同的屏蔽原内容以及规则类型；及根据选择屏蔽原内容和规则类型生成所述数据查询子系统的脱敏规则，所述脱敏规则对应所述用户权限。本申请还提供一种脱敏规则配置程序、应用服务器及计算机可读存储介质。本申请提供的脱敏规则配置方法、程序、应用服务器及计算机可读存储介质，可以通过脱敏规则配置的可视化，以及针对不同用户权限赋予不同的脱敏规则，实现了脱敏规则的直观且简易的管理，提高了脱敏系统的可维护性。
Patent WO-2019071975-A1 (WO)
Title: Cooking appliance control method and apparatus, and cooking appliance
Inventor: WANG XIAOXIANG
IPC: A47J36/32
Filed: 2018-06-19
Abstract: A cooking appliance control method and apparatus, and a cooking appliance, the control method being used to form scorched rice and comprising: acquiring a first control command used to characterize formation of scorched rice (S10); controlling internal temperature of the cooking appliance to be in a first pre-determined temperature range, and maintain the temperature for a first pre-determined length of time (S20). When there is cooked rice in the cooking appliance, the rice capable of being fresh-cooked, or being leftover rice, the rice may be heated for a period of time, turning the rice into clay pot rice having scorched rice; the present invention can overcome the rapid heat dissipation of an inner container in the prior art, and the inconvenience of making scorched rice or clay pot rice having scorched rice after rice is done cooking, and can cause the scorched rice or the scorched rice of the clay pot rice having scorched rice to not absorb water and become damp again, making palatability good, and having good food qualities.
Patent WO-2020014959-A1 (WO)
Title: Fingerprint identification method, fingerprint identification apparatus and electronic device
Inventor: YU XINHUA
IPC: G06K9/00
Filed: 2018-07-20
Abstract: The present application provides a fingerprint identification method, a fingerprint identification apparatus, and an electronic device, whereby whether a fingerprint collected by a fingerprint sensor is from a real finger can be identified according to a gradient characteristic of a fingerprint image, costs are saved, and the security of fingerprint identification is also improved. The method comprises: acquiring a fingerprint image of a target pressing a fingerprint sensor; processing the fingerprint image to obtain gradient information of the fingerprint image; and determining whether the target is a real finger according to the gradient information of the fingerprint image.
Patent WO-2019218456-A1 (WO)
Inventor: HUO LI
IPC: G06Q10/06
Filed: 2018-07-25
Abstract: 一种岗位人力预测方法，包括：从人力资源系统服务器获取待招聘岗位类别集合中，各个岗位类别对应的当前招聘要求信息、当前目标保费增速及当前成本率值；从保费系统服务器获取当前目标保费增速对应的基准保费；根据当前目标保费增速及基准保费进行计算，得到各个岗位类别对应的当前目标保费；根据各个岗位类别对应的当前目标保费及当前成本率值进行计算，得到各个岗位类别对应的当前目标成本；分别根据岗位类别集合中，各个岗位类别对应的当前招聘要求信息、当前目标保费及当前目标成本，采用已训练好的人力预测模型，得到各个岗位类别对应的当前人力需求数。
Patent WO-2019095723-A1 (WO)
Title: 信息发送、接收方法及装置、存储介质、处理器
Inventor: GAO BO
IPC: H04B7/06
Filed: 2018-07-27
Abstract: 本发明公开了一种信息发送、接收方法及装置、存储介质、处理器；其中，信息发送方法包括：在波束相关参数集合中的K个元素超过与K个元素对应的第一类门限的情况下，生成第一类信令；向第二通信节点发送第一类信令；其中，第一类信令中携带有与参考信号相关的信息；其中，K为大于或者等于1的整数。
Patent WO-2020029148-A1 (WO)
Title: Method and apparatus for calibrating collimator of radiotherapy device
Inventor: LI JIULIANG
IPC: A61B6/00
Filed: 2018-08-08
Abstract: A method and apparatus for calibrating a collimator, which relate to the field of medical equipment. The method comprises: when a collimator (302) is moved to M positions, respectively obtaining ray projection images after sequentially passing through a collimation hole on the collimator (302) and an isocenter plane (S401); according to the ray projection images, determining a target position among the M positions to maximize the degree of alignment of the collimator (302) (S402); and recording position parameters corresponding to the target position, so that the collimator (302) is controlled to move to the target position when a gamma knife device is used for treatment (S403). Thus, the position of the collimator (302) of the gamma knife device may be calibrated.
Patent WO-2020015046-A1 (WO)
Title: Surgical suture with natural antibacterial drug sustained release function and preparation method therefor
Inventor: LI GANG
IPC: A61L17/12
Filed: 2018-08-21
Abstract: Disclosed are a surgical suture with a natural antibacterial drug sustained release function and a preparation method therefor. The antibacterial surgical suture with a long-lasting antibacterial performance is prepared by adopting a composite structure knitting technology and using silk fibroin as a coating carrier to carry a natural antibacterial drug. The material of the surgical suture has good mechanical properties and a long-lasting drug sustained release effect, and is capable of inhibiting or killing bacteria and reducing surgical site infection.
Patent WO-2019047953-A1 (WO)
Title: Group based beam reporting and channel state information reference signal configuration in new radio systems
Inventor: WANG GUOTONG
IPC: H04W16/28
Filed: 2018-09-10
Abstract: Embodiments of the present disclosure describe methods and apparatuses for group based beam reporting and channel state information reference signal configuration in new radio systems.
Patent WO-2020000709-A1 (WO)
Title: 多面键合led灯丝
Inventor: ZHOU ZHIHAI
IPC: F21S4/00
Filed: 2018-09-21
Abstract: 一种多面键合LED灯丝，包括具有引脚（150）的安装板（110）和覆盖于安装板（110）上的封装胶体（120）。安装板（110）具有至少第一安装面（311）和第二安装面（312），第一安装面（311）和第二安装面（312）相对设置且分别固设有若干个LED芯片。这种结构的LED灯丝可实现多面固晶焊线发光，提高了灯丝的整体光效，有效解决了灯丝产品不同位置光色不一致的问题。且该种结构封装的LED灯丝发光时，灯丝整体散热均匀，能有效提升灯丝产品的使用功率及可靠性。
Patent WO-2019062736-A1 (WO)
Title: Electronic device and communication method
Inventor: LIU WENDONG
IPC: H04B7/0408
Filed: 2018-09-26
Abstract: The present disclosure relates to an electronic device and a communication method. An electronic device for a first communication device side comprises a processing circuit, wherein the processing circuit is configured to: determine, according to a priori information, a transmission order of multiple transmission beams of a first communication device during beam scanning which is to be executed on communication from the first communication device to a second communication device; and control the use of the multiple transmission beams for beam scanning in the determined transmission order.
Patent WO-2019137048-A1 (WO)
Inventor: FANG YINLI
IPC: H02K41/035
Filed: 2018-10-10
Abstract: L'invention concerne un actionneur optique (302), comprenant : une base (100); un module d'objectif (202), comprenant deux premières faces latérales (204) placées en regard l'une de l'autre; et de multiples fils d'alliage à mémoire de forme (203), qui forment deux groupes de fils, les deux groupes de fils étant respectivement disposés sur les deux premières faces latérales (204). Deux extrémités de chacun des fils d'alliage à mémoire de forme (203) sont respectivement fixées à un dispositif de fixation d'extrémité de base (206) et à un dispositif de fixation d'extrémité d'objectif (207); et la direction d'une force obtenue, agissant sur le module d'objectif (202), des deux groupes de fils est cohérente avec la direction d'un axe optique du module d'objectif (202) afin d'amener le module d'objectif (202) à se déplacer dans la direction de l'axe optique du module d'objectif (202) par extension et rétraction des fils d'alliage à mémoire de forme (203) des deux groupes de fils.
Patent WO-2020029424-A1 (WO)
Title: Lamination production system for photovoltaic assembly, and photovoltaic assembly transport device
Inventor: YANG JIANFENG
IPC: B65G47/91
Filed: 2018-10-17
Abstract: A lamination production system for a photovoltaic assembly and a photovoltaic assembly transport device, pertaining to the technical field of photovoltaics. The photovoltaic assembly transport device comprises a support frame (1), a sliding base (2), a gripper assembly (4), and multiple first lifting assemblies (3). The sliding base (2) is slidably disposed at the support frame (1). The gripper assembly (4) is disposed at the sliding base (2), and is used to grip a photovoltaic assembly (400). The multiple first lifting assemblies (3) are connected between the gripper assembly (4) and the sliding base (2), Each of the first lifting assemblies (3) is capable of raising and lowering independently, and the multiple first lifting assemblies (3) drive the gripper assembly (4) to raise and lower relative to the sliding base (2). The photovoltaic assembly transport device improves production efficiency and reduces the defect rate of products.
Patent WO-2020087413-A1 (WO)
Title: Cell information processing method and apparatus, and electronic device and readable storage medium
Inventor: LI WEIQING
IPC: H04W36/08
Filed: 2018-10-31
Abstract: Disclosed are a cell information processing method and apparatus, an electronic device and a readable storage medium, relating to the technical field of mobile communications. The method comprises: when an electronic device registers to a target cell, acquiring parameter information, wherein the parameter information comprises at least one of a target moment, resident duration of the electronic device in the target cell or the identifier of the target cell, and the target moment is any moment after registering to the target cell; determining whether the parameter information meets a stay standard; and if the stay standard is met, stopping execution of an operation of registering to an adjacent cell of the target cell. By stopping execution of a register operation on an adjacent cell, the method can fundamentally avoid registering to the cell so as to avoid being connected to a pseudo base station corresponding to the cell.
Patent WO-2020062413-A1 (WO)
Inventor: LIU FANCHENG
IPC: G02F1/1335
Filed: 2018-11-01
Abstract: Disclosed in the present invention is a liquid crystal display device, mainly comprising a liquid crystal panel, a first polarizer, a second polarizer, and a backlight module, the first polarizer being arranged beneath the liquid crystal panel, the second polarizer being arranged above the liquid crystal panel, and the backlight module being arranged beneath the first polarizer. In addition, the liquid crystal display device is provided with a sensor region and a sensor, the backlight module is provided with an opening corresponding to the sensor region, and the sensor is arranged inside of or beneath the opening. In the present invention, when the liquid crystal display device is in a powered-off state, a user is unable to see the sensor from the outside, but when the liquid crystal display device is in a powered-on state, the user can see the sensor.
Patent WO-2019184368-A1 (WO)
Title: 一种高纯度rhNGF的制备方法
Inventor: LIU WENCHAO
IPC: C07K14/48
Filed: 2018-11-08
Abstract: 提供了一种从CHO细胞培养物中得到高纯度rhNGF的方法。结合了阳离子交换层析和疏水作用层析方法，其特征是，在两种方法层析前，分别增加了清洗步骤。
Patent WO-2019223256-A1 (WO)
Inventor: LI XINGWEI
IPC: F25D11/02
Filed: 2018-11-15
Abstract: 冰箱的冷冻室（12）内设置有供固化液态水的制冰单元，冷藏室（11）内设置有向制冰单元提供液态水的储水盒（3），储水盒（3）与隔断冷藏室（11）、冷冻室（12）的隔板（10）间隔设置，基于此，冷冻室（12）内部的冷量无法通过隔板（10）直接对储水盒（3）内部的液态水进行制冷，储水盒（3）内的液态水无结冰风险，且隔板（10）的厚度尺寸也无需过大，有效避免了对冰箱有效容积的占用。
Patent WO-2019101163-A1 (WO)
Inventor: WEI CHIAHUNG
IPC: H04W72/12
Filed: 2018-11-23
Abstract: La présente invention concerne un procédé qui comprend le déclenchement, par une entité de commande d'accès au support (MAC) d'un dispositif d'équipement utilisateur (UE), d'une première demande de planification (SR) pour un premier canal logique, le premier canal logique n'étant pas configuré avec une ressource de canal de commande en liaison montante physique (PUCCH) valable pour la première procédure SR ; et la réalisation, par l'entité MAC de l'UE, d'une pluralité de procédures en réponse au déclenchement de la première procédure SR, les procédures consistant à : lancer une procédure d'accès aléatoire (RA) et annuler la première procédure SR.
Patent WO-2019105415-A1 (WO)
Inventor: KE XIUHUA
IPC: G06F17/00
Filed: 2018-11-29
Abstract: La présente invention concerne un procédé de traitement d'images, un dispositif de traitement d'images, un dispositif informatique et un support d'informations lisible par ordinateur. Selon le procédé : des informations d'images d'une pluralité d'images à traiter sont acquises ; une première classification est effectuée sur la pluralité d'images à traiter sur la base des informations d'images pour acquérir au moins un premier ensemble d'images ; une seconde classification est effectuée sur des images dans chacun du ou des premiers ensembles d'images selon une règle de classification prédéfinie, pour acquérir au moins un second ensemble d'images correspondant à chacun du ou des premiers ensembles d'images ; et le ou les seconds ensembles d'images correspondant à chacun du ou des premiers ensembles d'images sont affichés sur une interface d'un dispositif informatique.
Patent WO-2020093492-A1 (WO)
Title: 显示面板和显示装置
Inventor: HUANG SHISHUAI
IPC: G02F1/133
Filed: 2018-11-30
Abstract: 一种显示面板（100）和显示装置，显示面板（100）包括：第一基板（110）和对置设置的第二基板（120）；设置在第一基板（110）上的导电层（130）；夹设于第一基板（110）和第二基板（120）之间的框胶（140），且位于第一基板（110）和第二基板（120）的边缘位置；设置在第一基板（110）边缘的防护层（150），框胶（140）的外侧，覆盖在导电层（130）对应框胶（140）外侧的部分；设置在框胶（140）的外侧、与框胶（140）紧密贴合的辅助密封层（160），并覆盖防护层（150）。
Patent WO-2020034496-A1 (WO)
Title: Graphene fluoride, preparation method therefor, and application thereof, and epoxy resin composite material having same
Inventor: ZHANG ZHI
IPC: C08K3/04
Filed: 2018-12-06
Abstract: Disclosed are a graphene fluoride, preparation method therefor, and application thereof, and an epoxy resin composite material having same. The preparation method comprises: intercalating a solvent between graphite fluoride sheets as an intercalating agent; and then performing microwave stripping to obtain a graphene fluoride.
Patent WO-2020062594-A1 (WO)
Inventor: KANG CHIH TSUNG
IPC: G02B5/00
Filed: 2018-12-10
Abstract: The present application relates to a polarizing plate and a display device. The polarizing plate comprises: a first phase compensation film having a relatively large refractive index and provided with multiple protruding structures, wherein part of a surface of each protruding structure is a curved surface; and a second phase compensation film having a relatively small refractive index, wherein the second phase compensation film is provided with multiple grooves matching the protruding structures.
Patent WO-2020124388-A1 (WO)
Inventor: LI WEIQING
IPC: H04W36/20
Filed: 2018-12-18
Abstract: 本申请实施例公开了一种小区干扰检测方法、装置、移动终端以及存储介质，涉及移动终端技术领域。该方法应用于移动终端，所述方法包括：在第一时间段内检测目标小区的第一信号值，在第二时间段内检测目标小区的第二信号值，其中，第二时间段晚于第一时间段，判断第一信号值是否满足第一范围，并且判断第二信号值是否满足第二范围，其中，第二范围的最大值大于第一范围的最大值，第二范围的最小值小于第一范围的最小值，当该第一信号值满足第一范围且第二信号值超过第二范围时，确定该目标小区受到干扰。本申请实施例通过检测并判断目标小区在第一时间段和第二时间段的信号值的变化范围，确定目标小区是否受到干扰并进行防范，提升移动终端安全。
Patent WO-2020034517-A1 (WO)
Inventor: XIAO KAI
IPC: H04W8/08
Filed: 2018-12-19
Abstract: L'invention concerne des procédés, un appareil et des systèmes pour fournir des schémas de mappage de blocs de signaux de synchronisation (SSB). Les techniques peuvent être mises en œuvre dans divers modes de réalisation pour permettre la transmission de SSB à l'aide de fréquences de spectre plus élevées. Les techniques prennent également en compte diverses longueurs de préfixe cyclique (CP) pour des raisons de peignabilité. Selon un aspect donné à titre d'exemple, l'invention concerne un procédé de communication sans fil. Le procédé comprend la mise en correspondance d'un bloc de signal de synchronisation avec de multiples symboles ayant un premier espacement de sous-porteuse et la génération d'un motif de transmission pour un premier intervalle de temps qui comprend les multiples symboles pour le bloc de signal de synchronisation. Les multiples symboles proviennent d'un ensemble de groupes de symboles candidats non consécutifs.
Patent WO-2019128850-A1 (WO)
Title: 自动售货机
Inventor: ZENG XU
IPC: G07F11/16
Filed: 2018-12-21
Abstract: 提供了一种自动售货机，包括机柜（100），机柜（100）上设置有控制器、水平输送机构和至少一个取货单元（2），取货单元包括取货口（21）、若干储货组件（22）和间隔机构（23），取货口（21）设置于机柜（100）上，各储货组件（22）沿水平输送机构的输送方向排列设置，间隔装置包括与取货口（21）对应的滑移门（23a）和用于隔离储货组件（22）的阻隔件（23b），阻隔件（23b）和滑移门（23a）分隔成若干用于放置储货组件的取货腔，水平输送机构、阻隔件（23b）和滑移门（23a）分别与控制器电连接。该自动售货机能够实现稳定快速出货，使得售货机满足易碎易变形商品的供应，且售货机货物容纳量多，提高其空间利用率。
Patent WO-2019134534-A1 (WO)
Title: 一种e-10-羟基-2-癸烯酸在制备防治骨质疏松症的药品或保健品中的应用
Inventor: ZHAO WEIXUAN
IPC: A23L33/12
Filed: 2018-12-21
Abstract: 本发明公开了一种E-10-羟基-2-癸烯酸在制备防治骨质疏松症的药品或保健品中的应用，所述药物或保健品中的有效成分仅为E-10-羟基-2-癸烯酸，所述E-10-羟基-2-癸烯酸来源于人工合成或从蜂王浆中提取。本发明首次公开了E-10-羟基-2-癸烯酸的一种新用途，通过实验证明，E-10-羟基-2-癸烯酸对骨质疏松症具有显著的防治效果，因此其能够在制备防治骨质疏松症的药品或保健品中得到应用，而且E-10-羟基-2-癸烯酸性质稳定、制备方法简单、成本低廉、食药同源，将其应用于制成防治骨质疏松症的药品或保健具有成本低、防治效果好、用量少、长期服用无任何毒副作用等优势，在医药或保健品领域将具有广阔的应用前景。
Patent WO-2020073499-A1 (WO)
Title: 连接器及连接器组件
Inventor: LIANG SHUOZHEN
IPC: H01R13/629
Filed: 2018-12-24
Abstract: 一种连接器(10)，包括线缆(200)和线缆连接器(100)，该线缆(200)设有第一焊脚(211)，第一焊脚(211)设有第一助摩擦结构；该线缆连接器(100)配置为与待连接的电路板(300)连接固定，该电路板(300)设有第二焊脚(310)，线缆连接器(100)具有适配收容第一焊脚(211)的容置槽(102)，该容置槽(102)的底面开设开口，以使第一焊脚(211)与第二焊脚(310)直接接触，进而加强了第一焊脚(211)和第二焊脚(310)的连接强度，不需要插针来使线缆(200)与电路板(300)电连接，线缆连接器(100)结构简单，生产成本低。还涉及一种连接器组件(20)。
Patent WO-2019134600-A1 (WO)
Inventor: LIU RUOPENG
IPC: G10K11/172
Filed: 2018-12-29
Abstract: An acoustic metamaterial, comprising: N g  periodically-arranged metamaterial units, wherein the N g  is an integer greater than or equal to 3. Each metamaterial unit comprises a plurality of periodically-arranged sub-cycle units (6), each sub-cycle unit (6) comprises two piezoelectric elements, and the two piezoelectric elements on the sub-cycle units (6) are respectively connected to two branches of a negative capacitor (2). By means of the N g  periodically-arranged metamaterial units, each metamaterial unit comprising the plurality of sub-cycle units (6), and the two piezoelectric elements on each two sub-cycle units (6) being respectively connected to two branches of the negative capacitor (2), a piezoelectric metamaterial utilizing a negative capacitance circuit network in a paired interconnection type can be branched by a damping circuit having less negative capacitance, and in a specific wide frequency band, particularly a low-frequency band, a local resonance forbidden band gap having better attenuation performance can be generated.
Patent WO-2020093584-A1 (WO)
Inventor: MAO LINFENG
IPC: B01J20/34
Filed: 2019-01-03
Abstract: 一种吸附有机废气中有机物的吸附剂(包括活性炭、活性焦、沸石等)吸附饱和后的脱附再生工艺以及脱附再生过程中产生的尾气的处理工艺。吸附剂在预埋有蒸汽喷射系统的再生罐(2)中进行脱附再生，蒸汽喷射系统包括主蒸汽管道(102)和设置于主蒸汽管道(102)上的若干树枝状次级蒸汽管道(103)，每根次级蒸汽管道(103)均设有蒸汽喷嘴，蒸汽喷射系统被吸附剂包埋。通入过热蒸汽对再生罐(2)内吸附剂加热，吸附剂所吸附的大部分有机物被高温脱附或者被高温裂解、碳化脱附，并用蒸汽吹扫去除吸附剂孔隙中有机物和碳化物，使吸附剂活化再生。再生过程中产生的尾气经尾气处理设备，具体为尾气冷凝处理设备、尾气焚烧处理设备或尾气先冷凝再焚烧处理设备进行处理。
Patent WO-2019149030-A1 (WO)
Title: High-pressure pneumatic machine
Inventor: LIU YONGXIANG
IPC: F04C18/04
Filed: 2019-01-04
Abstract: Provided is a high-pressure pneumatic machine, comprising a cylinder (4), a rotor (5) and a high-pressure air storage tank, wherein the rotor (5) is rotatably mounted inside the cylinder (4) by means of a support shaft and is arranged coaxially with the cylinder (4); four outer covers (13) are mounted in the circumferential direction of the cylinder (4); an air inlet gate plate (3) is slidably mounted inside each of the outer covers (13); a reset mechanism and a lubrication mechanism are mounted between the air inlet gate plates (3) and the outer covers (13); the high-pressure air storage tank is located outside the cylinder (4), is in communication with the interior of the outer covers (13) by means of an air inlet pipe (1), and drives the air inlet gate plates (3) to slide; and three air-meeting protrusions are uniformly arranged in the circumferential direction of the rotor (5), and each of the air-meeting protrusions is formed in an integrated manner.
Patent WO-2019165851-A1 (WO)
Inventor: FAHL WILLIAM E
IPC: A61P25/00
Filed: 2019-01-04
Abstract: Members of the PrC-210 family of aminothiols, including PrC-211 and PrC-252, are shown to be highly effective in reducing ischemia-reperfusion injury in two preclinical models, including kidney transplant and myocardial infarct. PrC-210 is shown to be well tolerated, achieving up to 100% efficacy at 0.5MTD doses where there are no discernible rodent toxicities when systemically administered either by ORAL or IP routes. In what is likely the most important aspect of ischemia-reperfusion injury, at in vitro PrC-210 concentrations of 2-3 mM, the same PrC-210 concentrations which have been measured in IP or ORAL PrC-210 treated rodents, PrC-210 is 100% effective in preventing DNA damage in a direct ROS-scavenging assay. In the standard mouse kidney clamp/unclamp model of I-R kidney insult, all three of the aminothiols profoundly suppress (>80%) the kidney caspase levels seen in no drug treated controls; BUN levels in the I-R kidney mice are likewise reduced by PrC-210 and its analogs. In the mouse myocardial infarct model, a highly significant reduction in cardiac muscle death was observed when PrC-210 was administered systemically coincident with a 40-minute ligation and release of an anterior coronary artery. Complementary, in vitro studies using primary, neonatal, mouse cardiomyocytes showed a highly significant reduction of hydrogen peroxide-induced cardiomyocyte killing by coincident administration of the PrC-210 family aminothiols. PrC-210 family aminothiols are shown to suppress ischemia-reperfusion-induced cell and organ toxicities in a number of settings, significantly including organ transplant and myocardial infarct.