baber/WOPTO huggingface dataset:
Patent CH-514608-A (CH)
Title: Anti-protozoal piperazine derivs
Inventor: ANDREW STEPHEN TOMCUFCIK
IPC: A61K31/00
Filed: 1963-09-16
Abstract: Compounds of the general formula (I) - (I) where n = 3 or 4 - R1 and R2 = H or lower alkyl - R3 and R4 = H, lower alkyl or aralkyl - R5 is a carbon atom which is unsaturated by being a part of substituted aryl radical of the benzene type series or part of an aromatic heterocyclic ring of at least 5 ring atoms or by being a carbonyl carbon. and pharmaceutically acceptable salts thereof. - Compounds inhibit the growth of protozoa, particularly of the genus Trypanosoma. 1-(7-chloro-4-quinolinyl)-4-(3-dimethylaminopropyl) piperazine is active, in mice, against Trypanosoma cruzi, which causes Chagas's disease. - 1-(3-Dimethylaminopropyl)piperazine and its benzoyl derivative have been found active, in mice, against Schistosoma mansoni.
Patent CH-550232-A (CH)
Title: Yellowish-green azo dyes for cotton, wool, silk, etc
IPC: C09B29/42
Filed: 1970-05-15
Abstract: Yellowish-green azo cpds. for fast dyeing/printing of silk, leather, wool, synthetic superpolyamides and superpolyurethanes, polyesters, polyacrylonitrile and cellulosics such as linen, cellulose, regenerated cellulose, cotton, etc. contain an acid water-solubilising substituent and a gp. of formula: (wherein R is alkyl and R' is alkyl aryl). Also of interest are the azo cpds. not contg. water-solubilising gps. and complexes of these azo cpds. with heavy metals.
Patent CH-508864-A (CH)
Title: Safety device for time fuzes
Inventor: JOSEF MUELLER
IPC: F42C15/24
Filed: 1967-10-13
Abstract: Time fuse for a rocket projectile, has a safety device which includes two inertia weights. The fuse will prevent operation if the first inertia weight operates in transport or during acceleration of the projectile. The second inertia weight is mounted in the fuse housing surrounding the first inertia weight. A disconnectable lock for the first inertia weight will block it in its rear position. A safety finger engages the balance regulator of the timing mechanism.
Patent CH-546760-A (CH)
Title: Beta-pyridylcarbinol nicotinoylglycinate - with vasodilatory and hypolipaemic activity, prepn. from nicotinuric acid and nicotinyl alcohol
IPC: C07D213/82
Filed: 1972-01-05
Abstract: The novel cpd., beta-pyridylcarbinol nicotinoylglycinate (I) is prepd. by reaction of nicotinuric acid and nicotinyl alcohol in the presence of H2SO4 at 70-150 degrees C. (I) reduces capillary permeability, and has hypolipaemic and hypocholesterolaemic effects.