baber/WOPTO huggingface dataset:
Patent DE-60322371-D1 (DE)
Inventor: WONG PATRICK S L
IPC: A61P9/12
Filed: 2003-03-28
Granted: 2008-09-04
Abstract: A dosage form that facilitates the controlled release of an active agent at a desired release rate or release rate profile includes a bi-layer membrane system and an osmotic core. The bi-layer membrane system includes a semipermeable membrane and an osmosensitive membrane and forms an internal compartment occupied by the osmotic core. The osmotic core includes an active agent composition and a light push layer. A passageway is formed through the bi-layer membrane system and permits expulsion of the active agent composition from the dosage form during operation. The bi-layer membrane system and the osmotic core are formulated and formed to provide controlled release of the active agent included in the active agent composition, while simultaneously facilitating increased loading of active agent within a dosage form of given dimension and increasing the delivery efficiency of such active agent relative to prior osmotic dosage forms including a push layer.
Patent DE-60324592-D1 (DE)
Inventor: DAVIES OLIVER WILLIAM HARDWICKE
IPC: G01N33/32
Filed: 2003-10-30
Granted: 2008-12-18
Abstract: The present invention described a method of preconditioning a substrate in a web manufacturing process wherein the web manufacturing process includes a plurality of printing steps, the method comprising the steps of moving the substrate through the web manufacturing process under tension; heating the substrate as the substrate is passed through the printing steps, wherein the substrate temperature does not exceed a first predetermined temperature during the printing steps; and passing the substrate into a preconditioning station wherein the substrate is heated to a second temperature which exceeds the first temperature.
Patent DE-60326449-D1 (DE)
Inventor: VARSANI ARVIND DEVSHI
IPC: C12N15/37
Filed: 2003-05-19
Granted: 2009-04-16
Abstract: A method for producing a chimaeric human papillomavirus (HPV) L1 polypeptide containing a heterologous peptide, and in particular, a HPV L2 peptide comprising the steps of introducing a DNA sequence coding for the heterologous peptide into a DNA sequence coding for the L1 polypeptide; introducing the DNA sequence including the sequences for the L1 polypeptide and heterologous peptide into a host cell in which the DNA sequence can be expressed; causing expression of the DNA sequence; and recovering the resulting chimaeric L1 polypeptide which includes the heterologous peptide. The invention also describes a vector for use in the method, a host cell containing the vector, and a vaccine including the chimaeric HPV L1 polypeptide produced according to the method.
Patent DE-60329607-D1 (DE)
Inventor: JASTI VENKATESWARLU
IPC: A61K31/40
Filed: 2003-06-19
Granted: 2009-11-19
Abstract: The present invention relates to novel tetracyclic arylalkyl indoles, their derivatives, their analogues, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates, novel intermediates described herein and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel tetracyclic arylalkyl of the general formula (I), their derivatives, their analogues, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates, novel intermediates described herein and pharmaceutically acceptable compositions containing them. This invention also relates to process/es for preparing such compound/s of general formula (I), composition/s containing effective amount/s of such a compound and the use of such a compound/composition in therapy.
Patent DE-60330779-D1 (DE)
Inventor: SCHAFFER ARTHUR
IPC: C12Q1/68
Filed: 2003-05-15
Granted: 2010-02-11
Abstract: The present invention provides a method of identifying alkaline-alpha-galactosidases. Also provided are polynucleotide sequences encoding polypeptides having an alkaline-alpha-galactosidase activity, oligonucleotides and oligonucleotide analogs derived from the polynucleotide sequences, peptides and peptide analogues, antibodies recognizing same and methods of using same.
Patent DE-60334004-D1 (DE)
Inventor: SPEED NEIL HUGH FORSYTH
IPC: A47F5/11
Filed: 2003-08-01
Granted: 2010-10-14
Abstract: A display device which includes an elongate strip of sheet material having a plurality of product carrying pockets each pocket being provided with a pair of laterally spaced front sections in a plane substantially parallel to the plane of an adjacent rear section of the elongate strip, each front section being attached to the rear section at its upper edge respectively, by way of upper bridge portions, further attachment between a further section of the rear section and the front sections is provided by a lower bridge portion intermediate the front sections and which is attached adjacent the lower edges thereof.
Patent DE-68902113-D1 (DE)
Inventor: GROLLIER JEAN-FRANCOIS
IPC: A61K8/73
Filed: 1989-08-11
Granted: 1992-08-20
Abstract: 1. Composition for inducing and stimulating hair growth and/or reducing hair loss, characterised in that it contains, in a physiologically acceptable medium, at least one alkyl polyglycoside and at least one compound corresponding to the formula: <IMAGE>  in which R1 denotes a group <IMAGE> in which:  R3 and R4 may be selected from:  hydrogen and an alkyl, alkenyl, alkylaryl or cycloalkyl group; R3 and R4 can also form a heterocycle with the nitrogen atom to which they are linked, this heterocycle being selected from aziridinyl, azetidinyl, pyrrolidinyl, piperidinyl, hexahydro azepinyl, heptamethylenimine, octamethylenimine, morpholine and 4-(lower alkyl-piperazinyl groups, it being possible for the heterocyclic groups to be substituted on the carbon atoms with one to three alkyl, hydroxy or alkoxy groups; and the group R2 is selected from hydrogen and an alkyl, alkenyl, alkylalkoxy, cycloalkyl, aryl, alkylaryl, arylalkyl, alkylarylalkyl, alkoxyarylalkyl and/or haloarylalkyl group, as well as the physiologically acceptable addition salts with acids.
Patent DE-68903936-D1 (DE)
Inventor: AZZAM WEGDAN RIAD
IPC: C09J133/02
Filed: 1989-05-02
Granted: 1993-01-28
Abstract: The invention comprises an adhesive composition and accompanying coated substrate, such as prepasted wallpaper. The composition is formed from a low viscosity, water in oil emulsion which comprises a mixture of at least two emulsions of substantially linear, water soluble, high molecular weight cationic and anionic polymers; the anionic polymers comprising monomers selected from anionic monomers and mixtures of anionic monomers with non-ionic monomers and the cationic polymers comprising monomers selected from cationic monomers and mixtures of cationic monomers with non-ionic monomers. The adhesive composition and the coated substrates exhibit excellent qualities, particularly an improved resistance to excess water absorption during usage.
Patent DE-68911109-D1 (DE)
Inventor: WITEHIRA PITA
IPC: H01M16/00
Filed: 1989-05-24
Granted: 1994-01-13
Abstract: The present invention relates to batteries and battery systems. In particular, a battery is described which comprises a container which houses a plurality of cells. Each of the cells share a common negative terminal (4). Two or more positive terminal cells are provided. The specification also describes the use of such batteries to power cranking and auxiliary circuits according to a cell discharge management scheme. Methods of forming such batteries are disclosed in which alternate positive and negative electrode plates are provided and methods of forming such plates are disclosed in which layered structures are provided and by varying the number of layers thick and thin plates can be provided with different discharge characteristics.
Patent DE-68913727-D1 (DE)
Inventor: VOS EDDY
IPC: C11D3/33
Filed: 1989-05-23
Granted: 1994-04-14
Abstract: The present invention relates to novel chelating agents derived from iminodiacetic acid, having the formula <CHEM>  wherein R is selected from the group of  - (CH2)2OCH2CH3; -(CH2)3OCH2CH3;  - CH(CH3)CH2OH; -(CH2)3O(CH2)2CH3;  and M is either hydrogen or a salt-forming cation. Detergent and cleaning compositions, in particular hard-surface cleaning compositions, containing said chelating agents are also encompassed.
Patent DE-68913965-D1 (DE)
Inventor: KAWAMURA KIYOSHI
IPC: C07D405/12
Filed: 1989-12-25
Granted: 1994-04-21
Abstract: This invention relates to a method for producing a glycidyl ether of general formula (I), wherein A is an optionally substituted aryl or heteroaryl group and the asterisked carbon atom represents an asymmetric carbon atom, comprising reacting an aryl alcohol of the general formula A-OH, wherein A is as defined above, with an epihalohydrin in the presence of a quaternary ammonium salt and, if necessary, treating the reaction product with a base. This method can afford the glycidyl ether of formula (I), which is useful as an intermediate of drugs, especially a  beta -blocker, in a simplified manner with a high optical purity.
Patent DE-68916265-D1 (DE)
Inventor: WOOLARD FRANK
IPC: A01N43/36
Filed: 1989-11-29
Granted: 1994-07-21
Abstract: 1-Phenyl-3-carboxyamidopyrrolidones of the formula   <IMAGE>   in which R1 is H, alkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, phenyl, halophenyl, benzyl, halobenzyl, or alkyl substituted with alkoxy, alkyltyhio, phenyl, hydroxy or cyano; and R2 is H or alkyl; or R1 and R2 are combined as alkylene or alkyleneoxyalkylene; R3 is alkyl or alkenyl; R4 is H, halogen, CH3, CF3, CF2CHF2, OCF2CHF2, OCHF2, OCF3, SCH3, S(O)CH3, SO2CH3, methoxyiminomethyl, methoxyimino-1-ethyl, benzyloxyiminomethyl, or benzyloxyimino-1-ethyl;n is zero or 1; X is H or halogen; Y is O or S; and Z is O or S, are useful as herbicidal agents.
Patent DE-68924963-D1 (DE)
Inventor: BUBBERS J ERIC
IPC: C12R1/91
Filed: 1989-10-02
Granted: 1996-01-11
Abstract: A composition effective for treating or preventing diseases of Gram-negative bacterial origin comprises polyclonal immunoglobulins containing polyclonal antibodies against antigens of Gram-negative bacteria and monoclonal antibodies capable of binding with and neutralizing an antigen common to the endotoxin region of a variety of Gram-negative bacterial lipopolysaccharides.
Patent DE-68926233-D1 (DE)
Inventor: DJORDJEVICH LJUBOMIR
IPC: A61B5/053
Filed: 1989-06-28
Granted: 1996-05-15
Abstract: A method, and a device utilizing that method, for continuously, noninvasively measuring a patient's blood pressure. Discrete values of systolic and diastolic blood pressure are noninvasively determined and input to a microprocessor. A continuous non-pressure waveform signal is generated through noninvasive monitoring of the patient and is also input to the microprocessor. The microprocessor calibrates the continuous non-pressure waveform signal using the discrete blood pressure values, thereby generating a continuous waveform signal of blood pressure.
Patent DE-68927351-D1 (DE)
Inventor: CLEGG ANDREW
IPC: G01R31/36
Filed: 1989-11-29
Granted: 1996-11-21
Abstract: PCT No. PCT/GB89/01428 Sec. 371 Date May 29, 1992 Sec. 102(e) Date May 29, 1992 PCT Filed Nov. 29, 1989 PCT Pub. No. WO91/08494 PCT Pub. Date Jun. 13, 1991.A battery monitoring system (10) supplies the user of a battery power system with information indicating the capacity remaining in the battery (9) during discharge. During discharge the system (10) monitors various parameters and calculates on a rapid sampling basis derived parameters from algorithms stored in memory in tabulated form. The recharging efficiency is also evaluated, stored and updated on each charge/discharge cycle so that ageing of the battery (9) is monitored.
Patent DE-69000182-D1 (DE)
Inventor: LAUGIER JEAN-PIERRE
IPC: A61K31/135
Filed: 1990-04-19
Granted: 1992-08-13
Abstract: Cleansing composition having a pharmaceutical or veterinary action, for the topical treatment of dermatophytosis, containing in aqueous solution at least one antifungal component and at least one surfactant, this composition consisting of a solution containing as an antifungal at least one allylamine, and as a surfactant at least one anionic surfactant.
Patent DE-69004767-D1 (DE)
Inventor: BUSSINK JAN PROF
IPC: C08L23/04
Filed: 1990-08-28
Granted: 1994-01-05
Abstract: A composition is provided containing a polymer of unsaturated hydrocarbon , a C1-4 alkyl or hydroxyalkyl ether of starch having a degree of substitution of at least 0.25 for improving the biodegradability, and a vinyl or acryl copolymer as compatibility inducing agent. Preferably, the composition also contains a lubricant or plasticizer of the carboxylic acid type for the polymer.
Patent DE-69010199-D1 (DE)
Inventor: BARRETT ALAN
IPC: C07K16/40
Filed: 1990-04-27
Granted: 1994-07-28
Abstract: A pharmaceutical composition comprising purified chymopapain and a reducing agent is presented. The purified chymopapain in this composition has a specific activity against 1 mM of N- alpha -benzoyl-DL-arginine p-nitroanilide at 40 DEG  C. and pH 6.8 of between 3,000 and 4,500 units per mg, and contains less than 0.2% each of papaya proteinase III (PPIII), papain, and papaya proteinase IV (PPIV).
Patent DE-69016448-D1 (DE)
Inventor: MELLAND TRISTIAN GUY
IPC: B65D41/18
Filed: 1990-10-05
Granted: 1995-03-09
Abstract: PCT No. PCT/GB90/01537 Sec. 371 Date Jun. 2, 1992 Sec. 102(e) Date Jun. 2, 1992 PCT Filed Oct. 5, 1990 PCT Pub. No. WO91/04923 PCT Pub. Date Apr. 18, 1991.The dispensing container has a bottle with at least two compartments for accommodating different fluent components. The compartments are so designed that they dispense their contents at equal flow rates when the bottle it tilted. In addition, security is provided against cross-contamination of the contents of the different compartments when, after a dispensing operation, the bottle is righted again. The bottle is provided with a cap that seals off the outlets from the compartments simultaneously when fitted to the bottle. The cap can be a separate component or it can be provided as a flip-top cap. The bottle is made entirely of plastics material and directional pouring spouts can be provided to ensure that the contents of the compartments leave in well-defined streams during a dispensing operation.
Patent DE-69021060-D1 (DE)
Inventor: FIELDS DONALD LEE
IPC: C07F/
Filed: 1990-09-12
Granted: 1995-08-24
Abstract: There is disclosed a process for producing the alkali metal salts of N-phosphonomethylglycine which comprises heating to an elevated temperature a di-alkali metal salt of N-alkyl-N-(2-hydroxyethyl)aminomethylphosphonic acid.
Patent DE-69025378-D1 (DE)
Inventor: LARSSON KARE
IPC: A61K9/127
Filed: 1990-10-12
Granted: 1996-03-28
Abstract: The invention relates to an implant material composition for restoring bone tissue in a human or animal body. Said composition comprises a particulate biocompatible bone tissue substitute material distributed in a bioacceptable mixture of a) a water-based liquid and b) a monoglyceride and optionally c) a triglyceride, said ingredients a), b) and c) forming an L2-phase or a lamellary liquid crystalline phase and being present in such proportions within said phases that they are capable of being transformed into a cubic liquid crystalline phase or a reversed hexagonal liquid crystalline phase when contacted with an aqueous liquid. Thus, the phase conversion referred to imparts to the composition such a high viscosity that is works as an implant material as defined. There is also provided a method of preparing said composition comprising forming the L2 or lamellary phase and distributing the bone tissue substitute material therein. Moreover, there is provided a method of restoring lost bone tissue comprising applying the composition to a bone cavity and converting the same by contact with an aqueous liquid. The composition for use as an implant material composition as well as the use thereof for the manufacture of an implant product are also provided. Finally the invention relates to the restored implant bone tissue product obtainable from said composition by contact with said aqueous liquid.
Patent DE-69034009-D1 (DE)
Inventor: MARTINEAU BELINDA
IPC: C12N15/29
Filed: 1990-07-19
Granted: 2002-11-21
Abstract: Novel DNA constructs are provided which may be used as molecular probes or inserted into a plant host to provide for modification of transcription of a DNA sequence of interest in ovary tissue, particularly in very early fruit development. The DNA constructs comprise a transcriptional initiation regulatory region associated with gene expression in ovary tissue from immediately prior to anthesis through flower senescence.
Patent DE-69104081-D1 (DE)
Inventor: CORDONNIER ALAIN
IPC: B07B7/00
Filed: 1991-02-08
Granted: 1994-10-27
Abstract: A pneumatic centrifugal separator comprises guide vanes disposed along the generatrices of a fictitious cylinder having a vertical axis, the guide vanes being adapted to impart to a gas stream entering the fictitious cylinder a rotary motion about the vertical cylinder axis, and a rotor coaxially positioned in the interior of the fictitious cylinder, the rotor being equipped with a first set of vertical blades distributed uniformly along the periphery of the fictitious cylinder and a second set of blades disposed between the blades of the first set and the cylinder axis. A gas stream and particulate material to be sorted is introduced between the guide vanes and the rotor, and the gas stream charged with particles of dimensions smaller than predetermined dimensions and sorted out of the particulate material is drawn out of a central outlet. The second set of blades is arranged to guide the streams of gas coming through channels between adjacent vertical blades of the first set to the central outlet.
Patent DE-69105340-D1 (DE)
Inventor: LAMBERIGTS MARCEL
IPC: C23C28/02
Filed: 1991-04-12
Granted: 1995-01-12
Abstract: A thin layer of a metal chosen from nickel, cobalt and chromium is deposited electrolytically on the strip and the strip thus coated is passed through a bath of zinc which has an aluminium content of approximately 55 % by weight. The steel strip is preferably subjected to annealing under a protective atmosphere after the deposition of the abovementioned thin layer and before the strip is passed through the zinc-aluminium bath.
Patent DE-69106650-D1 (DE)
Inventor: MESNEL FRANCOIS
IPC: B60J10/08
Filed: 1991-09-18
Granted: 1995-02-23
Abstract: The invention relates to an elastomer strip having a U-section portion (3) that fits over a projecting component of a framework, and a tubular component adjoining one arm of the U. 
<??>According to the invention, the tubular component is formed by a band (6), a first lateral portion (6a) of which joins said arm of the U while the second lateral portion (6b) is able to be force-fitted between the U-section portion (3) of the strip and an adjoining portion (5) thereof, in order to form said tubular component. 
<IMAGE>
Patent DE-69106965-D1 (DE)
Inventor: IMAMOTO TOSHIHIKO C O NAGASAKI
IPC: B01D53/74
Filed: 1991-06-21
Granted: 1995-03-09
Abstract: An apparatus for treating an exhaust gas which has a dry type catalytic denitration apparatus on the upstream side of the exhaust gas and a plasma denitration apparatus on the downstream side of the dry type catalytic denitration apparatus. The apparatus of the present invention can solve problems which arise if the dry type catalytic denitration apparatus is singly used.
Patent DE-69110287-D1 (DE)
Inventor: HANSEN ERIC
IPC: G01N33/577
Filed: 1991-07-10
Granted: 1995-07-13
Abstract: PCT No. PCT/US91/04864 Sec. 371 Date Feb. 5, 1993 Sec. 102(e) Date Feb. 5, 1993 PCT Filed Jul. 10, 1991 PCT Pub. No. WO92/01228 PCT Pub. Date Jan. 23, 1992.The invention relates to a method of detecting gram-negative bacterial endotoxin using antibody capture combined with amoebocyte lysate chromogenic detection. The method is highly sensitive and rapid and may be used for detection of specific endotoxin. In a particular application, picogram levels of Haemophilus influenzae type b endotoxin are detected in plasma taken from previously infected mammals. In another particular application, the method is applied to the detection and diagnosis of disease, through the detection of endotoxin from disease-causing organisms. A specific example is the diagnosis of chancroid through the detection of endotoxin from H. ducreyi.
Patent DE-69115819-D1 (DE)
Inventor: WHITE STEVEN ANDREW CARL
IPC: B29K9/00
Filed: 1991-06-05
Granted: 1996-02-08
Abstract: Bottle gaskets are provided from a thermoplastic composition comprising a homogeneous blend of butyl rubber with other thermoplastic polymer. The gaskets provide an effective seal at a moderate pressure but permit venting at a higher pressure. They can be made by inserting molten heated thermoplastic material into the bottle cap and moulding it in the cap and cooling it to form the gasket.
Patent DE-69119665-D1 (DE)
Inventor: FOBARE WILLIAM FLOYD
IPC: A61P9/10
Filed: 1991-08-06
Granted: 1996-06-27
Abstract: The compounds of the formula: <CHEM> in which X, and Y are, independently, hydrogen, halogen, hydroxy, nitro, cyano, carboxyl, trifluoromethyl, phenyl, amino, alkylamino, dialkylamino, alkyl, alkoxy or phenylalkyloxy; R1 is hydrogen, alkyl, hydroxyalkyl, alkenyl, cycloalkyl, phenylcycloalkyl, 1-hydroxymethylphenethyl, 1-(t-butyl)dimethylsilyloxymethylphenethyl, 1-(t-butyl)dimenthylsilyloxy methylisopentyl, 1-hydroxymethylisopentyl, phenyl, benzyl or substituted phenyl or benzyl, where the substituents are alkyl, alkoxy, halogen, cyano, trifluoromethyl, amino, alkylamino, dialkylamino, nitro or phenyl, benzyl, phenethyl or R1 is thienyl, imidazolyl, thiazolyl, pyridinyl, pyrimidinyl, pyrazinyl, benzamidazolyl, phenylalkylpiperidinyl or morpholino; R2 is alkyl, cycloalkyl, phenyl, benzyl or substituted phenyl or benzyl in which said substituent is alkyl, alkoxy, halogen, cyano, trifluoromethyl amino, nitro, alkylamino or dialkylamino; and a pharmaceutically acceptable salt thereof; are ACAT inhibitors, some of which possess antioxidant properties.
Patent DE-69132213-D1 (DE)
Inventor: NAKAMURA MAOTO
IPC: B41J2/00
Filed: 1991-12-27
Granted: 2000-06-21
Abstract: An image forming apparatus having a plurality of electron emitting devices and luminescent members arranged into a matrix form on one surface of a substrate. As rows of electron emitting devices are successively driven, each luminescent member emits light according to a voltage applied to it or other members in accordance with an image information signal, when irradiated with a light beam from one of the electron emitting devices mated with it. <IMAGE>
Patent DE-69203677-D1 (DE)
Inventor: CARIMALI FELIX
IPC: F02K1/56
Filed: 1992-08-19
Granted: 1995-08-31
Abstract: A reversal well (17) for the passage of the flow reversed by a turbojet thrust reverser is delimited on one side by a deflection edge (108) integral with a fixed part (1). 
<??>The longitudinal sections (A,B,C,D) of the deflection edge (108) have a progressive curvature from one lateral edge of the reversal well to the other so as to enhance the control of the streams of the reversed flux. 
<IMAGE>
Patent DE-69206869-D1 (DE)
Inventor: SEIDEL RANDY R
IPC: B65B27/08
Filed: 1992-04-17
Granted: 1996-02-01
Abstract: A device for bundling a plurality of flat flexible structures (4) received serially from a feed conveyor (2), applying top (31) and bottom (32) protective sheets, and strapping the structure together. The device includes a support conveyor (16) adjacent to the feed conveyor and movable in a downstream direction along a path, a first conveyor (12) movable in the downstream direction adjacent and substantially parallel to said support conveyor, at least one first blade (5) on the first conveyor (12) movable in a perpendicular direction toward the support conveyor to a support position. The first blade acts as a rest for the structures (6), and is movable away from the support conveyor to an inoperative position out of the path. When in the support position, this first blade (5) advances in the downstream direction as the structures are deposited on edge onto the support conveyor, whereby a bundle (6) of structures is formed. <IMAGE>