baber/WOPTO huggingface dataset:
Patent CA-2472374-C (CA)
Title: Endovascular device for entrapment of particulate matter and method for use
Inventor: SHIMON DOV
IPC: A61F2/00
Filed: 2002-12-05
Granted: 2012-02-14
Abstract: A device and method for protecting a blood vessel. The device (7) may be a stent (2), for insertion in a large artery such as the ascending aorta (1), and may be combined with a filter (16). The device includes an outer wire frame rather than a stent.The stent may be made of at least one layer of mesh (12), which is typically attached or mounted to the arterial wall. Typically the size of the apertures of the mesh (12) at the top portion of the stent is smaller than the bottom portion of the stent. The device and method are particularly useful in preventing blockages of flow to the brain, but have other uses as well. An electric charge (14) may be placed on the device, for example, to prevent blood components from collecting.
Patent CA-2478187-C (CA)
Inventor: BRIGGS DENNIS A
IPC: F16L33/00
Filed: 2003-02-28
Granted: 2011-07-19
Abstract: La présente invention concerne des systèmes, des procédés et un dispositif destinés à améliorer l'efficacité de séparation de constituants de liquides, et notamment de liquides biologiques ou sensibles tels que le sang, et à améliorer le taux de traitement de constituants issus, par exemple, d'un volume de sang total donné par séparation des constituants en fonction de leur densité dans une cuve à centrifugation présentant une lumière multi-axiale. Ce dispositif, ce système et ce procédé permettent de supprimer la nécessité de réaliser une séparation discontinue du sang, et de réduire le temps requis pour traiter des patients souffrant de maladies ou d'états pathologiques induits par les lymphocytes T ou par les leucocytes à une durée inférieure à 70 minutes. Dans un aspect, l'invention concerne une cuve à centrifugation (10) comprenant un boîtier extérieur (100), une partie centrale (200), une plaque inférieure (300), une lumière (400), un premier canal de cuve (420) situé dans cette lumière (400) et servant à faire entrer le liquide (800), un deuxième canal de cuve (410) destiné à évacuer un premier constituant de liquide séparé (810), ainsi qu'un troisième canal de cuve (740) permettant d'évacuer un second constituant de liquide séparé (820).
Patent CA-2485580-C (CA)
Title: Process for producing optically active oxoheptenoic acid ester
Inventor: HORIUCHI TAKASHI
IPC: C07D215/14
Filed: 2002-11-14
Granted: 2009-11-03
Abstract: A novel process for producing an optically active (E)-7-[2-cyclopropyl-4-(4fluorophenyl) quinolin-3-yl]-5-hydroxy-3-oxohept-6-enoic acid ester of formula (III) which is important as an intermediate for synthesizing medicines, comprises reacting 1,3-bis(trimethylsilyloxy)-1-alkoxybuta-1,3-diene of formula (I) with (E)-3-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-prop-2-en-1-al of formula (II) in the presence of an optically active binaphthol-titanium complex obtained from 1,1'-bi-2-naphthol with titanium tetraisopropoxide, a metal salt and an amine, and then subjecting the reaction product to desilylation.   (see formula I)(see formula II)(see formula III)
Patent CA-2486849-C (CA)
Inventor: SCHAEFER JARED JOHN
IPC: A23L29/10
Filed: 2003-05-28
Granted: 2011-07-12
Abstract: Cette invention porte sur des procédés de production de polyesters d'acide gras polyol purifiés, partiellement estérifiés et sur les compositions dérivées de ces procédés. Les polyesters d'acide gras polyol purifiés, partiellement estérifiés, de l'invention sont notamment appropriés pour être utilisés dans différentes applications alimentaires, dans les boissons, les applications pharmaceutiques et cosmétiques. Les compositions ont une teneur en poids sec de polyol inférieure à environ 5 %; de solvant résiduel inférieure à environ 5 ppm; d'esters d'alkyle inférieur en dessous d'environ 700 ppm; en poids sec de savon inférieure à environ 5 % et un mélange d'acide gras libre; une teneur en poids sec de cendres inférieure à environ 3 %. Ces compositions ont également une valeur acide inférieure à environ 6.
Patent CA-2488422-C (CA)
Title: Stable solid medicinal ramosetron composition for oral administration
Inventor: NISHIDA AKITO
IPC: A61K47/38
Filed: 2004-01-30
Granted: 2008-08-19
Abstract: This invention is aimed to provide a stabilized formulation of ramosetron or a pharmaceutically acceptable salt thereof under a temperature/humidity condition, especially at a low content and relates to a stable oral solid drug composition of ramosetron or a pharmaceutically acceptable salt thereof, which is characterized by containing one or two or more members selected from the group consisting of an aliphatic carboxylic acid or an ester thereof, a hydroxycarboxylic acid or an ester thereof, an acidic amino acid, an enolic acid, an aromatic carboxyl compound or an ester thereof, and a carboxyl group-containing high-molecular substance, and to a stabilization method of the same. Also, this invention relates to a therapeutic agent of diarrhea-predominant irritable bowel syndrome containing from 0.002 to 0.02 mg of ramosetron hydrochloride as a daily dose or an equivalent molar amount of ramosetron or its pharmaceutically acceptable other salt as an active ingredient.
Patent CA-2490633-C (CA)
Title: Sac de rangement refermable avec elements de fermeture secondaires
Inventor: WINIARSKI PEGGY B
IPC: B65D33/01
Filed: 2003-06-27
Granted: 2008-04-08
Abstract: L'invention porte sur un sac de rangement refermable pr~sentant une premi­re face et une seconde face pourvues de cÙt~s ferm~s et d'une partie sup~rieure ouverte. Ce sac peut comporter ~ cÙt~ de la partie sup~rieure des ~l~ments de fermeture primaires, les ~l~ments de fermeture secondaires ~tant, eux, plac~s autour d'une ouverture dans au moins une des faces afin de permettre ~ l'air de s'~vacuer du sac apr­s la fermeture des ~l~ments de fermeture primaires.
Patent CA-2494997-C (CA)
Title: Silicone modified polyurea
Inventor: SMITH STUART B
IPC: C08G77/388
Filed: 2003-08-27
Granted: 2012-11-27
Abstract: The present invention includes a novel polyol prepolmer including an aliphatic amine, aromatic amine, or a mixture of both aliphatic and aromatic amines with an epoxy functional silicone to produce the novel polyol prepolymer chain extender. In another aspect of the invention, the novel polyol prepolymer chain extender is reacted with a polyisocyanate to produce a novel silicone modified polyurea having improved adhesion, chemical resistance, UV stability, and decreased shrinkage properties.
Patent CA-2495237-C (CA)
Title: Pince pour cordon de sucette
Inventor: ROEHRIG PETER
IPC: A41F3/02
Filed: 2003-09-09
Granted: 2008-10-14
Abstract: La présente invention concerne une pince (1) pour cordon de sucette, comprenant deux parties de pince (2) qui peuvent pivoter l'une par rapport à l'autre et présentent des zones de pincement (3) qui coopèrent. Lorsque cette pince (1) pour cordon de sucette est fermée, des surfaces internes se faisant face (6) des zones de pincement (3) reposent l'une contre l'autre. La surface (6) d'au moins une zone de pincement (3) est au moins partiellement constituée d'un matériau présentant une dureté inférieure à celle du matériau des parties de pince (2). Ces parties de pince (2) sont formées par les branches d'un profilé en U (8) dont le sommet (8') sert d'axe de pivot ou de zone de pivot aux parties de pince (2). Lorsque cette pince (1) pour cordon de sucette se trouve en position dégagée, ses zones de pincement (3) sont éloignées l'une de l'autre.
Patent CA-2495438-C (CA)
Title: Beam-steering and beam-forming for wideband mimo/miso systems
Inventor: MENON MURALI PARAVATH
IPC: H04B7/06
Filed: 2003-08-19
Granted: 2012-05-29
Abstract: Techniques to perform beam-steering and beam-forming to transmit data on a single eigenmode in a wideband multiple-input channel. In one method, a steering vector is obtained for each of a number of subbands. Depending on how the steering vectors are defined, beam-steering or beam-forming can be achieved for each subband. The total transmit power is allocated to the subbands based on a particular power allocation scheme (e.g., full channel inversion, selective channel inversion, water-filling, or uniform). A scaling value is then obtained for each subband based on its allocated transmit power.  Data to be transmitted is coded and modulated to provide modulation symbols.  The modulation symbols to be transmitted on each subband are scaled with the subband's scaling value and further preconditioned with the subband's steering vector. A stream of preconditioned symbols is then formed for each transmit antenna.
Patent CA-2502736-C (CA)
Inventor: WOBBEN ALOYS
IPC: F04B11/00
Filed: 2003-07-21
Granted: 2008-07-15
Abstract: The invention relates to a method and device for continuously desalinating water by reverse osmosis, particularly for desalinating sea water, according to which: salt water (10) is introduced by a delivery pump (1) into a pressure compensation device (2) while under a first pressure (p1); from the pressure compensation device (2), salt water (11) is continuously introduced into a membrane module (3) while under a second increased pressure (p2) and, inside of the membrane module, the salt water is separated by a membrane (6) into desalinated water (12) and concentrated salt water (13); the concentrated salt water (13) discharged from the membrane module (3) is continuously introduced into the pressure compensation device (2) while under appropriately the second pressure (p2) and is used therein for increasing the pressure of the salt water (10) introduced into the pressure compensation device (2) up to approximately the second pressure (p2) and for introducing the salt water (11) into the membrane module (3). In order to prevent malfunctions in the operation of and, possibly, damages to the membrane (6) caused by a reduced flow over the membrane surface, the invention provides that a continuous flow of the salt water (11) introduced into the membrane module (3) is maintained over the membrane surface of the membrane (6) by means of water discharged from a reservoir (15; 403; 20).
Patent CA-2507823-C (CA)
Inventor: RAMELLA JUAN
IPC: A61J1/10
Filed: 2004-02-03
Granted: 2012-01-03
Abstract: The invention relates to a bag comprising an assembly of two strong flexible outer sheets (1,2), through one of which sheets the access bushing (4) is affixed, wherein the interior of such bag is divided into two chambers by means of a third separating flexible sheet (7) provided with a screen-like stripe (9) with its distal end located at the bottom of the bag; said third separating sheet (7) which, correspondingly with said bushing (4) is provided with a bore (8) affixed around its edge onto the annular plane (10) of the bushing end projecting into the bag; of said two chambers, a first chamber is in communication, by means of the bushing, with its related solvent inlet and it is partially filled with the powdered solute, whereas the second chamber is provided inside with a layer (5) separate from the bag, selected among a woven or injected material or the like, freely extending from a semicircular recess (6) made in correspondence with said bushing (4) to the bottom of the chamber and wherein said bushing provides the necessary means for the exit of the solution thus achieved. The invention also relates to a process for manufacturing a bag according to the invention.
Patent CA-2508868-C (CA)
Inventor: TSUKUDA KEIICHIRO
IPC: B41J2/21
Filed: 2005-06-01
Granted: 2009-09-29
Abstract: An ink jet recording head comprising: three sets of nozzle arrays each of which comprises a large nozzle array which includes a first ejection outlet group and a small nozzle array which includes the second ejection outlet group, the small nozzle array being adjacent to the large nozzle array, wherein the first ejection outlet group includes an ejection outlet for ejecting ink, and the second ejection outlet group includes an ejection outlet, having an ejection outlet diameter smaller than the ejection outlet in the first ejection outlet group, for ejecting ink, wherein yellow, magenta and cyan inks are ejected to effect recording by the nozzle array sets when the ink jet recording head is moved in a main scan direction at a position opposing a recording material which is moving in a sub-scan direction, wherein in nozzle arrays constituted by two adjacent ones of the three nozzle array sets, the large nozzle array, the small nozzle array, the small nozzle array, the large nozzle array are arranged in the order named, in the main scanning direction, and wherein one of the two adjacent nozzle array sets ejects the cyan ink; the other one of the two adjacent nozzle array sets eject the magenta ink; a nozzle array set not constituting the two adjacent nozzle array sets ejects yellow ink.
Patent CA-2513102-C (CA)
Title: Substituted pyrazoles, compositions containing such compounds and methods of use
Inventor: PARMEE EMMA
IPC: A61K/
Filed: 2004-01-23
Granted: 2011-03-22
Abstract: The present invention relates to substituted pyrazoles, compositions containing such compounds and methods of treatment The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.
Patent CA-2517702-C (CA)
Inventor: LAVELLE SHAY
IPC: A61F2/95
Filed: 2005-08-31
Granted: 2009-12-15
Abstract: A stent is made from a coiled wire and is very smooth along its length and as well its ends. The stent is thus highly atraumatic to patients, and because of its smooth surfaces, it presents a surface to which it is difficult for microbes to cling. The stent may be used in a minimally invasive procedure, such as for a ureteral stent, and may also be used percutaneously. Similar stents may be used in other body areas, such as in draining the biliary tract, the gastro-intestinal tract, hepatic procedures, and in vascular procedures as well.
Patent CA-2521776-C (CA)
Inventor: PARK AERI
IPC: A61P19/10
Filed: 2002-05-21
Granted: 2006-04-25
Abstract: Novel crystalline forms of [R-(R*,R*)~-2-(4-fluorophenyl)-.beta., .DELTA.;  dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt atorvastatin designated Form a, Form VI, Form VII, Form VIII, Form IX, Form X, Form XI, Form XII, Form XIII, Form XIV, Form XV, Form XVI, Form XVII, Form XVIII, and Form XIX are characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, and Alzheimer's disease.
Patent CA-2530646-C (CA)
Inventor: SCHALKEN JACK A
IPC: C12Q1/68
Filed: 2004-06-30
Granted: 2015-11-03
Abstract: The present invention relates, in general, to prostate cancer. More specifically, the present invention relates to a method to diagnose prostate cancer in a, patient by detecting a PCA3 sequence, and more particularly a PCA3 RNA, the PCA3 sequence detected in a sample from the patient being specifically associated with prostate cancer. In a particular embodiment the method and kit enables an amplification of a PCA3 RNA through an exon-exon junction of a spliced PCA3 mRNA. The invention also related to methods and kits to detect such an amplified PCA3 RNA, using a probe which spans the amplified exonexon junction. The invention also relates to kits containing nucleic acid primers and kits containing nucleic acid primers and nucleic acid probes to diagnose, assess, or prognose a human afflicted with prostate cancer. In particular the methods and kits are designed to detect a PCA3 RNA which lacks one intron or more, and in particular case is intron-less.
Patent CA-2535598-C (CA)
Title: Tool holder block and sleeve retained therein by interference fit
Inventor: STEHNEY STEPHEN C
IPC: B23C9/00
Filed: 2006-02-08
Granted: 2012-04-24
Abstract: A hollow sleeve is mounted in a hole of a holder block to receive a rotary cutter bit. The sleeve includes a front flange and a shank extending rearwardly from the front flange and defining a longitudinal axis. The shank includes an outer periphery having a radially stepped configuration, wherein an outer surface of the shank includes a plurality of axially adjacent surface sections that become successively smaller in cross-section in a direction away from the flange, Each surface section occupies one-third of the hole length. Each surface section has longitudinally spaced front and rear ends, wherein a portion of each surface section situated between its front and rear ends is spaced farther from the axis than are the front and rear ends. Each surface section has a generally longitudinally extending groove formed therein,
Patent CA-2537820-C (CA)
Title: Processus de preparation de medicaments hydrosolubles comprenant la complexation de la forskoline dans la cyclodextrine
Inventor: MAJEED MUHAMMED
IPC: A61K9/00
Filed: 2004-09-02
Granted: 2013-03-26
Abstract: L'invention concerne des solutions aqueuses de diterpènes, tels que la forskoline, les congénères de ceux-ci, des analogues et des dérivés de ceux-ci, jusqu'à une concentration de 6 % approximativement, ces solutions étant préparées au moyen de cyclodextrine substituée de manière appropriée comme agents de solubilisation. En l'absence de cyclodextrine, quelques diterpènes, tels que la forskoline, sont solubles dans l'eau uniquement jusqu'à des concentrations d'environ 0.001 % . De telles solutions aqueuses peuvent être utilisées par voie topique et systémique sous la forme de préparations pharmaceutiques, cosmétiques et neutriceutiques renfermant des diterpènes, tels que la forskoline et des congénères.
Patent CA-2538606-C (CA)
Title: Fluid control valve
Inventor: HOFFMAN HERBERT L
IPC: B60H1/24
Filed: 2004-08-26
Granted: 2010-03-23
Abstract: A valve is provided for controlling a flow of a fluid between a first environment and a second environment. The valve includes a frame adapted to fit within a perimeter of an aperture in a divider separating the first environment from the second environment. The valve additionally includes a first gate movable within the frame to control a flow of the fluid through the aperture between the first environment and the second environment. The first gate includes a substantially aerodynamically clean surface substantially free from protrusions disrupting the flow of the fluid over the first gate surface. Additionally, the first gate includes a trailing edge having a baffle adapted to cover an aft edge of the frame when the first gate is positioned to have a small opening angle. The baffle includes a plurality of 3-D notches in a front side of the baffle. The valve further includes a second gate movable within the frame to control a flow of the fluid through the aperture between the first environment and the second environment. The second gate also includes a substantially aerodynamically clean surface substantially free from protrusions disrupting the flow of the fluid over the second gate surface. Additionally, the second gate includes a trailing edge comprising a plurality of 3-D notches in a front side of the trailing edge.
Patent CA-2541277-C (CA)
Title: Gathering randomness in a wireless smart card reader
Inventor: ADAMS NEIL
IPC: H04L9/14
Filed: 2006-03-30
Granted: 2011-05-10
Abstract: A device coupled to a smart card reader may request random data from a smart card inserted into the smart card reader, and the smart card reader may incorporate the random data into its randomness pool. A device having a source of random data may have a driver installed thereon for another device and the driver may extract random data from the source and transmit it securely over a wireless communication link to the other device. The other device, which may be a smart card reader, may incorporate the extracted random data into its randomness pool. A smart card reader may incorporate traffic received from a smart card inserted therein into its randomness pool.
Patent CA-2543261-C (CA)
Inventor: BESTEBREURTJE PIETER
IPC: G01N29/00
Filed: 2004-10-19
Granted: 2013-01-22
Abstract: A method for ultrasonic testing of an object, wherein at least one test moment an ultrasonic test signal (S1, S2) is transmitted into the object (2), while after a particular verification period (.DELTA.t1, .DELTA.t2) measured from said test moment, an ultrasonic verification signal (S1', S2') is transmitted into the object (2), a possible echo of said test signal (S1, S2) being received from said object (2) at a particular first measuring moment, the possible echo being accepted as being the echo (E1, E2) of said test signal (S1, S2) only when the echo (E1', E2') of the verification signal is received at a particular second measuring moment. In addition, the invention provides an apparatus, evidently intended and designed for carrying out such a method and a use of such an apparatus.
Patent CA-2544291-C (CA)
Inventor: IMANIDIS GEORGIOS
IPC: A61K9/00
Filed: 2004-09-13
Granted: 2013-01-08
Abstract: The invention concerns a transdermal delivery system for controlled dispensing of an active substance to and through a porous surface. A certain amount of fluid comprising at least one active substance and at least one solvent is dispensed into an administration reservoir. In the administration reservoir the at least one solvent is separated from the administration reservoir by a solvent recovery means such that the active substance achieves a certain level on an interface device which is permeable for the one active substance.  Thereby the active substance is absorbable via diffusion from the interface device by a porous surface to be treated.
Patent CA-2546665-C (CA)
Title: Protein from horn fly saliva that disrupts hemostasis
Inventor: CUPP MARY S
IPC: A61K38/57
Filed: 2004-11-24
Granted: 2014-06-17
Abstract: Compositions and methods for preventing hematophagous infestation of cattle are provided, directed at isolated proteins that disrupt platelet aggregation.  Also provided are nucleotide sequences encoding the proteins. The exemplary haematollogen protein was isolated from the salivary glands of Haematobia irritans. The compositions are useful as veterinary vaccines in prevention of blood-feeding in cattle by the infesting horn fly and are also useful in treatment of thrombosis.
Patent CA-2556728-C (CA)
Title: Stroke-variable engine
Inventor: WATANABE SEI
IPC: F02B75/32
Filed: 2006-08-21
Granted: 2010-04-27
Abstract: In a stroke-variable engine, the position of a center of gravity of a subsidiary connecting rod is determined so that a distance between the position of the center of gravity of the subsidiary connecting rod and an axis of a crankpin is smaller than a distance between a point of connection of a main connecting rod to the subsidiary connecting rod and the position of the center of gravity as well as a distance between a point of connection of a control rod to the subsidiary connecting rod and the position of the center of gravity. Thus, 0.5-order vibration generated in the subsidiary connecting rod is lowered, engine vibration is suppressed, and noise generated with the vibration is suppressed.