baber/WOPTO huggingface dataset:
Patent WO-2022214588-A4 (WO)
Title: Moyens et procédés pour améliorer le transfert de gènes ciblant un récepteur
Inventor: BRAUN ANGELA
IPC: C12N15/867
Filed: 2022-04-07
Abstract: La présente invention concerne le domaine du transfert de gènes. Plus particulièrement, la présente invention concerne un procédé permettant d'améliorer le transfert de gènes ciblant un récepteur dans un lymphocyte T primaire en tant que cellule hôte, ledit procédé comprenant la mise en contact d'une cellule hôte comprise dans un échantillon avec un véhicule de transfert de gènes comprenant un agent de ciblage se liant particulièrement à CD3 et un acide nucléique d'intérêt à transférer dans la cellule hôte en présence d'un inhibiteur de tyrosine kinase capable d'inhiber la tyrosine kinase LCK dans ladite cellule hôte et la culture de ladite culture de cellules hôtes obtenue pendant une durée et dans des conditions permettant le transfert de gènes ciblant un récepteur. La présente invention concerne également un procédé de préparation d'un médicament ainsi qu'un médicament comprenant un véhicule de transfert de gènes comprenant un agent de ciblage se liant particulièrement à CD3 et un acide nucléique d'intérêt à transférer dans des lymphocytes T primaires et un inhibiteur de tyrosine kinase capable d'inhiber la tyrosine kinase LCK dans lesdits lymphocytes T primaires. En outre, concerne également un inhibiteur de tyrosine kinase destiné à être utilisé dans le transfert de gènes ciblant un récepteur dans ledit lymphocyte T primaire chez un sujet en ayant besoin, ledit inhibiteur de tyrosine kinase étant capable d'inhiber la tyrosine kinase LCK dans un lymphocyte T primaire en tant que cellule hôte ou véhicule de transfert de gènes destiné à être utilisé pour améliorer le transfert de gènes ciblant un récepteur dans ledit lymphocyte T primaire chez un sujet en ayant besoin, le véhicule de transfert de gènes étant utilisé en combinaison avec un inhibiteur de tyrosine kinase capable d'inhiber la tyrosine kinase LCK dans un lymphocyte T primaire en tant que cellule hôte.
Patent WO-2017158220-A4 (WO)
Inventor: VEIGA RIVERO RICARDO
IPC: A61F5/01
Filed: 2017-03-15
Abstract: Dispositivo de inmovilización postraumática y procedimiento para su fabricación. El dispositivo comprende una forma arquitectónica, de geometría redondeada, constituida por al menos dos piezas rígidas (1a, 1b), complementarias, a modo de malla (11) que delimitan sendas cavidades cóncavas y que comprenden: unos extremos curvos (12) de unión, y unos cierres provistos de unos relieves (13) de acoplamiento de unas anillas tóricas elásticas (2) que establecen el apriete de las piezas (1a, 1b) rígidas entre sí. La invención incluye un procedimiento de fabricación de dicho dispositivo.
Patent WO-2015079183-A4 (WO)
Title: Plaquette de coupe, outil de coupe avec une telle plaquette et procédés de fabrication et de réparation d'un tel outil
Inventor: GRUNDER TIMOTHÉE
IPC: C04B37/02
Filed: 2014-11-28
Abstract: Plaquette de coupe brasée sur un corps d'outils de coupe (101) se composant d'un substrat métallique (11) en forme de plaquettes avec une surface de fixation au corps de l'outil, une couche (12) d'alliage de brasage haute température, une couche intermédiaire, une plaquette céramique (14). La couche d'alliage de brasage relie le support métallique (11) de la plaquette céramique (14) par l'intermédiaire de la couche métallique (13). Une couche de brasage basse température (16) relie la plaquette de coupe (1, 1') au corps d'outil (101).
Patent WO-2008117308-A4 (WO)
Title: Nouveau dérivé ester d'acide diazonaphtoquinonesulfonique et de bisphénol utile dans la formation de motifs submicroniques photolithographiques et son procédé de préparation
Inventor: REDDY VUMMADI VENKAT
IPC: C07C303/28
Filed: 2008-03-20
Abstract: La présente invention porte sur de nouveaux dérivés esters d'acide diazonaphtoquinonesulfonique et de bisphénol. Plus particulièrement, la présente invention porte sur un revêtement de photorésist comprenant une résine soluble dans les alcalis, un composé photo-actif et un agent tensio-actif. Le film de photorésist préparé fait moins d'un micron. Le composé photo-actif est soluble ou gonflable dans les solutions alcalines aqueuses et est un ester d'acide diazonaphtoquinonesulfonique et de bisphénol, représenté par la formule générale (A) dans laquelle DNQ représente un groupe 2-diazo-1-naphtoquinone-4-sulfonyle, 2-diazo-1-naphtoquinone-5-sulfonyle, 1-diazo-2-naphtoquinone-4-sulfonyle et R1 représente un groupe alkyle, aryle ou aryle substitué. L'invention porte également sur un procédé pour le revêtement et l'imagerie de la composition sensible à la lumière.
Patent WO-2019226060-A4 (WO)
Title: A turbine blade and a turbine comprising such a blade
Inventor: LICZNERSKI PAWEŁ
IPC: F03D1/06
Filed: 2019-05-20
Abstract: The invention relates to a turbine blade having a suction surface (6) the profile of which comprises starting from a leading surface (3): - at least one segment (SEG1-SEGn) which has a curve inflection point (C1-Cn) and which is formed by a first convex curve (KA1-KAn) having a first mean curvature radius (RA1-RAn) and a first curvature length (LA1-LAn), a second convex curve (KB1-KBn) having a second mean curvature radius (RB1-RBn) and a second curvature length (LB1-LBn), and by one concave curve (KC1-KCn) having a third mean curvature radius (RC1-RCn) and a third curvature length (LC1-LCn); and - a terminal segment (SEGt) formed by a concave curve (Kt) having a terminal mean curvature radius (Rt) and a terminal curvature length (Lt); characterized in that for each segment (SEG1_SEGn) having a curve inflection point (C1-Cn): the ratio (RC:RA) of the third mean curvature radius (RC) to the first mean curvature radius (RA) ranges from 0.55 to 0.95; the ratio (RB:RC) of the second mean curvature radius (RB) to the third mean curvature radius (RC) ranges from 0.35 to 0.75; the ratio (LC:LA) of the third curvature length (LC) to the first curvature length (LA) ranges from 0.55 to 0.95; the ratio (LB:LA) of the second curvature length (LB) to the first curvature length (LA) ranges from 0.35 to 0.75; and for the terminal segment (SEGt): the terminal mean curvature radius (Rt) is smaller than the first mean curvature radius (RAn) of the preceding adjacent segment (SEGn) having a curve inflection point (Cn); a chord (CHt) of the terminal segment (SEGt) is slanted relative to a chord (CHn) of the preceding adjacent segment (SEGn) having a curve inflection point (Cn) at an obtuse angle (a(n;t)); the ratio (LCHt:LCHn) of the length (LCHt) of the chord (CHt) of the terminal segment (SEGt) to the length (LCHn) of the chord (CHn) of the preceding adjacent segment (SEGn) having a curve inflection point (Cn), ranges from 0.55 to 0.95.
Patent WO-2008109368-A4 (WO)
Title: Composés d'acide nucléique permettant d'inhiber l'expression de gène vegfr et utilisations de ceux-ci
Inventor: QUAY STEVEN C
IPC: A61P35/00
Filed: 2008-02-28
Abstract: La présente invention concerne des molécules d'acide ribonucléique méroduplex (ARNmd) qui peuvent diminuer ou étouffer l'expression de gène VEGFR (par exemple, FLT1, KDR, FLT4). Un ARNmd de cette invention comprend au moins trois brins qui se combinent pour former au moins deux régions double brin non chevauchantes séparées par une encoche ou un espace dans lequel un brin est complémentaire à un ARNm FLT1, KDR ou FLT4. De plus, le méroduplex peut avoir au moins une uridine qui est une 5-méthyluridine, un acide nucléique bloqué, ou facultativement d'autres modifications, et n'importe quelle combinaison de ceux-ci. L'invention concerne également des procédés de diminution de l'expression d'un gène VEGFR dans une cellule ou chez un sujet pour traiter une maladie liée à VEGFR.
Patent WO-2011097117-A4 (WO)
Title: Techniques permettant de mettre en correspondance des cours avec des exigences de programme
Inventor: REYNOLDS JOHN
IPC: G06Q10/00
Filed: 2011-01-27
Abstract: Une évaluation d'un cours extérieur peut se baser sur des mises en correspondance cours-exigences qui ont été préalablement établies pour l'institution cible. En conséquence de l'évaluation, le cours extérieur peut être mis en correspondance avec des exigences de programme particulières pour un étudiant particulier, ce qui permet au cours extérieur de répondre aux exigences de programme particulières auprès de l'institution pour l'étudiant particulier. L'évaluation du cours peut être automatique ou elle peut être effectuée par une personne chargée de l'évaluation. Les mises en correspondance cours-exigences peuvent être globalement établies et peuvent s'appliquer à tous les étudiants et candidats de l'institution cible, ou elles peuvent être particulières au candidat et ne s'appliquer qu'à l'étudiant pour lequel la mise en correspondance a été établie. Les informations concernant à la fois les mises en correspondance cours-exigences globalement établies et les mises en correspondance cours-exigences spécifiques à un candidat qui ont été préalablement établies pour l'institution peuvent être utilisées afin d'évaluer un cours extérieur pour un étudiant particulier.
Patent WO-2012129095-A4 (WO)
Title: Attache d'acheminement empilable
Inventor: HOBSON BLAKE
IPC: B23K1/00
Filed: 2012-03-16
Abstract: Attache d'acheminement empilable à monter sur un équipement utilisant un outil à souder. Cette attache d'acheminement empilable comprend un corps et au moins une partie aile. Une saillie de soudage dépasse de la face inférieure du corps. Chaque partie aile peut dépasser du corps et comprend un port d'acheminement dans lequel vient s'insérer une ligature de câble destinée à fixer des câbles à l'attache d'acheminement empilable. Ladite attache d'acheminement empilable est conçue pour qu'une pluralité de telles attaches puisse être regroupée et former une pile. Les attaches peuvent être empilées dans un distributeur utilisé pour les distribuer individuellement en vue du soudage d'une attache par l'outil de soudage sur l'équipement. L'outil de soudage fait fondre la saillie de soudage et plonge l'attache dans le métal en fusion pour une soudure rapide et solide.
Patent WO-2013052545-A4 (WO)
Title: Compositions de soin des cheveux et procédés d'utilisation
Inventor: COMBS MARY JANE
IPC: A61Q5/12
Filed: 2012-10-03
Abstract: L'invention concerne des compositions de soins des cheveux comprenant d'environ 0,0005 % à environ 5 % d'apigénine, d'environ 0,15 % à environ 12 % d'un agent solubilisant, dans lesquelles l'agent solubilisant comprend un groupe fonctionnel amine, et au moins environ 20 pour cent en poids d'un support aqueux, la composition ayant un pH compris entre environ 3 et environ 10, et des procédés pour les préparer. Ces compositions de soin des cheveux peuvent être appliquées sur une zone quelconque du cuir chevelu ou des cheveux, dans laquelle une apparence plus saine des cheveux est souhaitée.
Patent WO-2013184727-A4 (WO)
Inventor: AULD JACK R
IPC: A61F2/16
Filed: 2013-06-04
Abstract: An intraocular lens inserter can include an energy storage portion, an actuator portion, and a lens support portion. The energy storage portion can include a compressible energy storage device, such as a compressible fluid, springs, and other devices. The inserter can include an actuator portion operating with a substantially incompressible fluid, such as liquids or other noncompressible fluids. The actuator can be configured to provide an operator with control over the release of energy from the energy storage portion so as to move a plunger for the discharge of a lens from an intraocular lens cartridge.
Patent CH-685802-A5 (CH)
Title: Pneumatic rinser for treating gum pocket tooth interstices
Inventor: WALKHOFF KLAUS WILHELM
IPC: A61C17/02
Filed: 1992-02-03
Abstract: The rinser drives the rinsing liq. from the enclosed container by pressurised gas, after actuation of an outlet valve, through valve connected treatment cannulae to the gum location to be treated. The pressure in the container is pref. generated by an immersion double cylinder with hollow piston and handle, and a non-return valve.  The generated pressure may be released by a coaxial outlet valve controlled by fingers and located at the double cylinder top. To the outlet valve may be coupled one or more treatment cannulae, matching the various mouth accessibility.
Patent CH-689588-A5 (CH)
Title: Child seat shell
Inventor: PETER BRESCH
IPC: B60N2/28
Filed: 1997-09-19
Abstract: The child seat shell has an integrated ring anchor (4) to which the car-side safety belt can be fixed. The seat locating surface (2) can be used as a pin and also as a hole for a counterpiece. A locking arrangement (3) is an integrated component part of the seat shell form, as is also the ring anchor.  TECHNOLOGY FOCUS - POLYMERS - The seat is produced as a plastic injection moulded part.
Patent CH-677703-A5 (CH)
Title: Automatic car park control system - uses optical and/or acoustic scanning of each vehicle eliminating need for parking tickets
Inventor: FATIO JEAN-LOUIS DR
IPC: G07B15/04
Filed: 1989-02-27
Abstract: The automatic car park control system monitors the entry and exit of each vehicle to determine the overall parking time and calculate the corresponding parking tariff. The vehicle entry and/or exit monitoring is effected optically and/or acoustically by optical scanning of the vehicle number plates, with subsequent electronic analysis and comparison of the obtained information with stored information held by a central computer (33). Pref. the entry and exit points for the vehicle are each provided with a barrier (16, 17; 26, 27) for halting the vehicle during the optical scanning and/or control the correct tariff is paid. ADVANTAGE - Eliminates need for parking tickets.
Patent CH-642556-A5 (CH)
Title: Apparatus for clamping at least one ski
Inventor: KASUBKE DIETMAR
IPC: A63C11/04
Filed: 1980-01-30
Abstract: The apparatus serves for the clamping of at least one ski in order for the running surfaces of the ski to be machined or repair work carried out on the ski. It has a clamping device (12) on a support (10), on which are arranged, at a distance from one another, two ski support apparatuses (24, 26) which are adjustable as to height and can be fixed by means of a fixing member (28, 46), and between which the clamping apparatus (12) is located. <IMAGE>
Patent CH-688788-A5 (CH)
Title: Food product with container and paste incorporated in it
Inventor: FERRERO PIETRO
IPC: A23P20/20
Filed: 1994-05-03
Abstract: A food product with a container and paste incorporated in it comprises a filler substance (6) different from the paste (3), included in a compartment or cell, with a peripheral wall (5). Also claimed is a container for the product, having supplementary wafers (2a,2b). The walls (5) have a free edge virtually aligned with the connection plane of components (2a,2b), forming cells (4) containing aromatic material such as chocolate or a dry-fruit-aroma cream.
Patent CH-682424-A5 (CH)
Title: Contacting method for testing electronic component or circuit board - using test modules which can be freely displaced relative to measuring table supporting tested component or circuit board to match size of latter
Inventor: SCHEIDEGGER HANS R
IPC: G01R31/01
Filed: 1991-05-14
Abstract: The contacting method for measuring electrical test parameters uses a number of fully autonomous contact modules (1), which are freely displaceable relative to a measuring table (2) supporting the component or circuit board (4) being tested. When the tested component or circuit board is normally covered by a protective band, the latter is cut to allow access to the required test points, with subsequent sealing of the cut board after testing, via a joining strip. The contact modules (1) pref. have pivoted contact arms (3) lowered into contact with the test points, the contact press provided by weights (5, 6). USE/ADVANTAGE - For quality control testing of surface-mounted-devices etc. Adaptable to different component sizes without modification to allow low-cost testing.
Patent CH-678098-A5 (CH)
Title: Solar powered nocturnal illuminator for gravestone - consists of photoelectric and photovoltaic cells assembly with accumulators and lamp circuitry
Inventor: MERCURIO SALVATORE
IPC: F21V23/00
Filed: 1990-05-23
Abstract: The illuminator comprises photovoltaic cells (1) generating electricity for storage in an accumulator (5) during the day. A photoelectric cell (4) transmits the electricity, at night only, to the lamps (3) of the gravestone (8). An electric circuit (2) and a light radiation panel (7) also make up the installation.
Patent CH-692175-A5 (CH)
Title: Sofa bed
Inventor: PREMER HEINZ
IPC: A47C17/17
Filed: 1997-08-15
Abstract: Seat or bed cushions (4) are mounted on a carriage (3) which can be pulled out from the chair frame (1,2). An extra cushion (6) with frame and upholstered sections (6',6") normally lies upright next to the chair backrest (2), but to convert the chair into a bed it can be rotated about bearings in the chair frame with the aid of a parallelogram joint (7) so that it lies in a horizontal position. The joint baseplate (8) is fastened to the furniture frame and the belt (11) between the two joint links is secured to the extra cushion. When the extra cushion is not being used it lies in the back of the chair frame with its upholstered section facing the backrest. This cushion is supported by the pulled out carriage when the bed is being used.
Patent CH-626782-A5 (CH)
Title: Process for preparing a protein-containing animal feed.
Inventor: MUELLER HANS DR ING
IPC: A23K10/32
Filed: 1977-03-08
Abstract: In a process for preparing a protein-containing animal feed using microorganism proteins, the microorganisms are mixed with starch-, cellulose- and fat-containing additives as filtration aids, separated, dried and pelletised. The dried, protein-rich and cellulose-containing composition serves as a feed additive for poultry, cattle and pigs.
Patent CH-679938-A5 (CH)
Title: Needle for tightening or drawing in stitches in knitted goods - has needle shank surface equipped with rhomboid pattern section and which embosses pattern in spiral shape
Inventor: TAESCHLER BERNHARD
IPC: D04B17/00
Filed: 1988-10-13
Abstract: Needle features a needle body with a needle shank, the surface of which has at least one section with a rhomboid pattern starting at the free end. The pattern is embossed on the shank in a spiral shape. The needle tip is slender while the needle point is rounded. The needle body consists of heat-treatable steel and is nickel-coated. ADVANTAGE - The needle is cheap to manufacture, eliminates defects in knitwear reliably and is simple to use.
Patent CH-582607-A5 (CH)
Title: Shaft cover lifting mechanism - has pinion fitted with driving and locking wheels which are in mesh with vertical rack
IPC: B66F19/00
Filed: 1975-04-01
Abstract: The shaft cover lifting mechanism has two rails secured to each other at the ends so as to form a slot between them and a bracket. The rails (1) are secured at one end to a bearing housing (5) containing a pinion meshing with a vertical rack equipped with a baseplate, and which is guided in the housing. The protruding end of the pinion shaft has fixed to it a driving wheel (14) with bosses on it for engagement by a crowbar etc, and also a locking wheel engaging with a catch (18). A loose crowbar is provided, and the bracket slides along the rails. A top stirrup is provided, to act as a carrying handle.
Patent CH-627487-A5 (CH)
Title: Process for preparing sulpho-free basic azo compounds
Inventor: BLASS ULRICH DR
IPC: C09B44/04
Filed: 1977-04-28
Abstract: New sulpho-free basic azo compounds of the formula <IMAGE> where the symbols are as defined in Claim 1, are obtained by coupling the diazo compound of an amine of the formula <IMAGE> with a coupling component of the formula <IMAGE> The compounds are useful for dyeing or printing textile or non-textile materials such as leather, plastic and paper.
Patent CH-595064-A5 (CH)
Title: Phenyl substd phenyl alkyl ethers
Inventor: KARRER FRIEDRICH DR
IPC: C07C43/205
Filed: 1974-04-26
Abstract: Phenyl substd phenyl alkyl ethers as parasiticides esp insecticides and acaricides for treating animals and plants
Patent CH-622890-A5 (CH)
Title: Controlled light shutter device
Inventor: THOMPSON ROBERT I
IPC: G02F1/17
Filed: 1977-05-20
Abstract: The device comprises a cell which contains, in a liquid medium, a suspension of particles, for example of quinine bisulphate periodide, which orient themselves under the influence of an electric field so as to modify the transmission of radiation through the suspension. In order to prevent or retard the agglomeration of the particles in suspension, an ester of a phenol and of a carboxylic acid, for example phenyl acetate, is incorporated into the liquid medium.
Patent CH-579466-A5 (CH)
Title: Transparent document wallet - with intermediate opaque film
IPC: B42F7/00
Filed: 1974-05-10
Abstract: In a transparent sachet or wallet formed by three superimposed films pref. plastic films joined together by weld - or adhesive - seams, an opaque intermediate film is provided between the transparent outer film and either has porous properties or is provided on each side with fluted surfaces. Adhesion of the transparent sachet walls is eliminated as well as the view of the back of oppositely situated documents of differing size and/or shape.
Patent CH-607206-A5 (CH)
Title: Tangential record player tone arm
Inventor: GRANDJEAN RAYMOND DIPL ING
IPC: G11B3/14
Filed: 1975-09-08
Abstract: Tangential record player tone arm is pivoted to curved vertical arm and both arms carry counter-weights
Patent CH-597298-A5 (CH)
Title: (4)-Piperidyl hydroxybenzyl-malonates and -malonamides
Inventor: RASBERGER MICHAEL DR
IPC: C07D211/58
Filed: 1975-11-07
Abstract: (4)-Piperidyl hydroxybenzyl-malonates and -malonamides for use as plastics stabilisers
Patent CH-560099-A5 (CH)
Title: Plastic foil coated with polystyrene foam insulation - for use as artificial leather, wrapping flowers in winter or for mfg. garment
IPC: B32B27/00
Filed: 1973-10-17
Abstract: The plastic foil, which may be grained, has a layer of polystyrene foam material adhered to it, pref. by heat welding. The material may be used as artificial leather, for wrapping flowers in winter or for making garments.
Patent CH-590810-A5 (CH)
Title: Organoleptic oxygenated alicyclic derivs - giving galbanum or juniper oil-like odours to perfume compsns. soaps etc.
IPC: C07C45/74
Filed: 1974-01-29
Abstract: Cpds. of formula (I): (with a satd. ring or an isolated double bond in the 1-, 4- or 6-posn. or two double bonds in the 1- and 4-, 1- and 5- or 4- and 6-posns. of the rign as indicated by the dotted lines, in which n is 0 - 2, Z is bonded at the 1- or 6- posns. of the righ to a C atom and may be -CO, -SOR8 or where R8 is an acyl gp. and R9 are, singly, 1-6C alkyl, or, together 2-6C alkenylyl gps., Y is O or CH2 and R1, R2, R3, R4 and R5 are each H or one is methyl and all the others are H and R6 and R7 are each 1-3C alkyl or one is H and the other alkyl) have organoleptic props. Cpds. (I) may have fruity, green, woody and oily notes reminiscent of galbanum or juniper oil and are very powerful, pref. 0.01-2 wt.% achieving desired effects.
Patent CH-626353-A5 (CH)
Title: Process for the preparation of a guanidine
Inventor: BAUDET PIERRE
IPC: C07D233/54
Filed: 1977-12-28
Abstract: A guanidine of formula I, in which all the substituents have the meanings given in Claim 1, is obtained by reaction of a compound of formula  Het-(CH2)m-SM, in which M is hydrogen or an alkali metal, with a compound of formula III. This process especially makes possible the preparation of the compound known under the name of cimetidine. The compounds have therapeutic qualities, especially against stomach ulcers, by blocking histamine H2-receptors. <IMAGE>