baber/WOPTO huggingface dataset:
Patent CA-2311679-A1 (CA)
Title: Use of a soluble recombinant human cd40l protein for inhibiting in vivo immune response
Inventor: LAZARUS ALAN H
IPC: A61K38/17
Filed: 1998-11-27
Abstract: The invention relates to a method for inhibiting in vivo immune response and to the use of a soluble recombinant human CD40L or a sequence within said soluble recombinant human CD40L containing the active binding site with CD40 for inhibiting an immune response. The invention also relates to a mouse model of human alloimmunization for testing in vivo effects of an immunotherapy or inhibition of a human antibody response.
Patent CA-2311976-A1 (CA)
Inventor: COOK PATRICK D
IPC: B63C11/48
Filed: 2000-06-19
Abstract: A dive rescue search device has a stanchion with a locating mechanism for the device mounted thereon and a search area determining device based on a reel of rope cooperating therewith to properly direct the search.
Patent CA-2318321-A1 (CA)
Inventor: COTTERET JEAN
IPC: A61K8/49
Filed: 1998-12-18
Abstract: The invention concerns a ready-to-use composition for dyeing human keratinous fibers and more particularly human hair, comprising in support suitable for dyeing keratinous fibers: (a) at least an enzyme such as laccase; (b) at least a cationic substantive or particular amphoteric polymer; (c) at least an oxidation coloring agent, as well as the dyeing methods using said composition.
Patent CA-2318576-A1 (CA)
Title: Antibodies, including fv molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use
Inventor: CHOWDHURY PARTHA S
IPC: A61K47/48
Filed: 1998-11-25
Abstract: Mesothelin is a differentiation antigen present on the surface of ovarian cancers, mesotheliomas and several other types of human cancers. Because among normal tissues, mesothelin is only present on mesothelial cells, it represents a good target for antibody mediated delivery of cytotoxic agents. The present invention is directed to anti-mesothelin antibodies, including Fv molecules with particularly high affinity for mesothelin, and immunoconjugates employing them. Also described are diagnostic and therapeutic methods using the antibodies. The anti-mesothelin antibodies are well-suited for the diagnosis and treatment of cancers of the ovary, stomach, squamous cells, mesotheliomas and other malignant cells expressing mesothelin.
Patent CA-2318614-A1 (CA)
Title: Power splitter for optical networks
Inventor: KOONEN ANTONIUS MARCELLUS JOZE
IPC: H04B17/40
Filed: 2000-09-12
Abstract: There is disclosed a network architecture comprising a first set of N serially connected power splitting centres connected at one end to receive a power signal and at another end to a termination point, each splitting centre having an output associated with a sub-network for delivering a portion of the power signal to that sub-network, wherein the power splitting factor in each power splitting centre is variable such that the portion of the power signal delivered to each sub-network is variable. The invention is described with particular relation to a double fibre ring optical network.
Patent CA-2318869-A1 (CA)
Inventor: SIDEBOTTOM CHRISTOPHER MICHAEL
IPC: A23G9/38
Filed: 1998-12-23
Abstract: Anti-freeze protein which can be derived from Lichen, said protein having an apparent molecular weight of from 20 to 28 kDa and having an N-terminal amino acid sequence which shows at least 80 % overlap with: A-P-A-V-V-M-G-D-A-E-S-F-G-A-I-A-H-G-G-L and modified versions and isoforms of this protein.
Patent CA-2320429-A1 (CA)
Title: Antimicrobial peptides and derived metapeptides
Inventor: SHEN ALEXANDER J
IPC: A61P31/04
Filed: 1999-02-17
Abstract: Antimicrobial agents comprising peptides are disclosed.
Patent CA-2324154-A1 (CA)
Title: Fungicidal 6-(2-halo-4-alkoxyphenyl)-triazolopyrimidines
Inventor: PFRENGLE WALDEMAR
IPC: A01N43/90
Filed: 1999-03-19
Abstract: The novel compounds of formula (I) (R1, R2, R3, L1 L2 and Hal are defined in the specification) show selective fungicidal activity.  These compounds may be processed with carriers, and optionally an adjuvant, to produce fungicidal compositions.
Patent CA-2324657-A1 (CA)
Title: Push and pull type roller exerciser
Inventor: KUO HUI KUEI
IPC: A63B22/20
Filed: 2000-10-30
Abstract: An exerciser includes a rod laterally secured in a housing and having two ends extended outward of the housing. One or more wheels are rotatably secured in the housing and include a lower portion extended downward beyond.the housing for engaging with a supporting surface. A pinion is secured to the wheel. A gear is rotatably secured in the housing and engaged with the pinion. One or more springs are secured between the gear and the housing for recovering the gear and may limit the rotational movement of the gear relative to the housing.
Patent CA-2324772-A1 (CA)
Title: Security arrangement for exchange of encrypted information
Inventor: IVANESCU VIOREL
IPC: G06Q20/02
Filed: 2000-10-30
Abstract: A method of remote loading of confidential information between a secure pin entry device and a Authorzing Institute using public and private key encryption techniques. In addition, a digital certificate uniquely identifying the terminal is provided by the terminal when a communication with the Authorzing Institute is originated. The Authorzing Institute confirms the authenticity of the digital certificate. This confirmation can occur using the public key of the Certificate Authority and/or confirmation can be made by contacting the Certificate Authority. In this way, confidence to use the public and private keys of the device and the Authorizing Institute for encryption is achieved, and financial keys and/or software can be encrypted downloaded to the device.
Patent CA-2326244-A1 (CA)
Inventor: TAI TOMISHIGE
IPC: H01R43/00
Filed: 2000-11-16
Abstract: A metallic thin film 15 is formed on a mold 11 having protrusions 12 complementary in shape to a conductor pattern to be formed; a substrate 17 having a transfer layer 16 of adherent (or adhesive) material applied to one side surface thereof is provided; and the transfer layer 16 side of the substrate is brought into intimate contact with the metallic thin film 15 laid over the protrusions 12, followed by pulling the transfer layer apart from the mold so as to transfer the metallic thin film 15 covering the protrusions 12 onto the transfer layer 16 to thereby form the conductor pattern 18 on the transfer layer 16.
Patent CA-2330625-A1 (CA)
Title: Methods and apparatus for dynamic smartcard synchronization and personalization
Inventor: HOHLE WILLIAM
IPC: G06Q20/36
Filed: 1999-05-04
Abstract: A system for personalizing and synchronizing smartcard data within a distributed transaction system includes smartcard access points (102) which initiate transactions with smartcards (120), one or more enterprise data collection units (112), a secure support client server, a card object database update system (106), one or more enterprise data synchronization interfaces (108), and an update logic system (110). Personalization of multifunction smartcards is accomplished using a security server configured to generate and/or retrieve cryptographic key information from multiple enterprise key systems during the final phase of the smartcard issuance process.
Patent CA-2331432-A1 (CA)
Title: Ex-vivo test kit for testing the effectiveness of reversers of multidrug resistance
Inventor: STEIN WILFRED DONALD
IPC: G01N33/15
Filed: 2001-01-18
Abstract: The invention provides an ex-vivo test kit for testing the effectiveness of reversers of multidrug resistance in the blood, serum or plasma of a patient containing said reversers, said kit comprising a plurality of cell membranes from drug-resistant cells, the cell membranes containing proteins which pump drugs and the membranes being respectively attached to a plurality of support surfaces and a dye which provides a light signal, which dye is pumped by the proteins contained in the membranes out of the membranes and into membrane sacs that are attached to the support surfaces.
Patent CA-2331833-A1 (CA)
Inventor: ELLIS JOHN TIMOTHY
IPC: C12N15/30
Filed: 1999-05-26
Abstract: Isolated nucleic acid molecules encoding Neospora caninum antigens, polypeptides forming N. caninum antigens, and uses of the nucleic acid molecules and the polypeptides for protecting and diagnosing neosporosis in animals.
Patent CA-2331920-A1 (CA)
Inventor: KOHARA MICHINORI
IPC: G01N33/576
Filed: 1999-06-24
Abstract: L'invention concerne un gène codant pour l'ARN polymérase, qui joue un rôle important dans la prolifération du virus de l'hépatite C; et une technique de criblage qui utilise ledit gène ou ladite ARN polymérase. Cette technique permet de détecter facilement un inhibiteur de l'ARN polymérase jouant un rôle important dans la prolifération du VHC.
Patent CA-2332994-A1 (CA)
Inventor: SUNG KIL YONG
IPC: F23Q2/16
Filed: 2000-03-24
Abstract: A safety mechanism of a utility lighter (1). In a first preferred embodiment, the safety mechanism includes a safety button (120) and a cam mechanism (60) having a fuel release lever (70), a cam lever (80), and a return spring (90). When the cam mechanism (60) is in the locked position, the cam lever (80) engages the stopper tab (110) of the trigger (100) to impede depression of the trigger (100), and the fuel release lever (70) closes the fuel release valve (31). The cam mechanism (60) is actuated by depressing the safety buttom (120).  As the safety buttom is depressed the cam lever (80) is disengaged out of alignment with the stopper tab (110) to permit depression of the trigger (100), the hub (61) rotates, and the fuel release lever (70) is actuated to open the fuel-release valve (31). As the safety buttom (120) is released, the return spring (90) urges the cam mechanism (60) into the locked position.
Patent CA-2334031-A1 (CA)
Inventor: BIEN DENISE JEAN
IPC: A47L13/17
Filed: 1999-06-24
Abstract: This invention discloses a substantially flat mechanically expandable pad (10), i.e., one positioned almost exclusively in the x-y plane, having an expandable member (35) therein that once activated expands the mechanically expandable pad (10) out of the x-y plane and into the z-direction. Such activation occurs when cinch members (22, 24) are used to contract the expandable member (35) in the x or y-directions bit cause its expansion in t he z-direction. The pad is useful for cleaning, polishing, buffing, etc. and th e expandable member has application in other types of absorbent articles.</SDO AB>
Patent CA-2334646-A1 (CA)
Title: An earplug
Inventor: HIRSHFELD EALLAN
IPC: A61F11/06
Filed: 1999-06-08
Abstract: An earplug (20) is provided which allows conversation to be conducted whilst inserted in the ear, and blocks out certain noise without substantially sealing the ear canal, and causing discomfort to the wearer. In one embodiment, the earplug includes a first cylindrical element (28) open at one end (30), having a substantially convex shape at its other end (34) for insertion into the outer ear canal, and a second element (32) which fits into the open end of the first cylindrical element to form a connecting juncture therewith. The first and second elements have air circulation means.
Patent CA-2335108-A1 (CA)
Title: An apparatus for reduction of selected ion intensities in confined ion beams
Inventor: BARINAGA CHARLES J
IPC: H01J27/02
Filed: 1999-06-15
Abstract: An apparatus for producing an ion beam having an increased proportion of analyte ions compared to carrier gas ions is disclosed. Specifically, the apparatus has an ion trap or a collision cell containing a reagent gas where in the reagent gas accepts charge from the analyte ions thereby selectively neutralizing the carrier gas ions. Also disclosed is the collision cell as employed in various locations within analytical instruments including an inductively coupled plasma mass spectrometer.
Patent CA-2335175-A1 (CA)
Title: Method and apparatus for recovery of water and slurry abrasives used for chemical and mechanical planarization
Inventor: FERRI EDWARD T JR
IPC: B24B37/04
Filed: 1999-05-25
Abstract: A method of recovering liquid and abrasives from an aqueous slurry containing finely divided, suspended solids comprising at least one filtering step utilizing a sintered metal membrane and/or ceramic membrane in conjunction with a method of measuring specific gravity or density, physically concentrating and separating the abrasive particles from the effluent allowing disposal through the normal industrial waste system or reuse of the supernatant liquid. The method is further used for recovery of solids for reuse in other, less critical applications thus reducing or eliminating the waste by-products of the polishing process.
Patent CA-2337197-A1 (CA)
Title: Microdevices for screening biomolecules
Inventor: WAGNER PETER
IPC: G01N33/53
Filed: 1999-07-14
Abstract: Methods and devices for the parallel, in vitro screening of biomolecular activity using miniaturized microfabricated devices are provided. The biomolecules immobilized on the surface of the devices of the present invention include proteins, polypeptides, polynucleotides, polysaccharides, phospholipids, and related unnatural polymers of biological relevance. These devices are useful in drug development, functional proteomics and clinical diagnostics and are preferably used for the parallel screening of families of related proteins.
Patent CA-2339833-A1 (CA)
Title: Blood sugar level controlling agent
Inventor: NAKAGAWA TSUTOMU
IPC: A61K38/28
Filed: 1999-08-10
Abstract: A blood sugar level controlling agent for diabetics to be insulinized which contains as the active ingredients an insulin receptor agonist and neurotrophin; utilization of the above two ingredients in preparing a blood sugar level controlling agent; and a method for controlling the blood sugar level of diabetics within the normal range by using these two ingredients. By using the above medicinal preparation in controlling the blood sugar level of diabetics to be insulinized, the effect of insulin can be potentiated and, at the same time, the side effects such as hypoglycemic shock can be relieved, thereby also enabling improvement in the compliance.
Patent CA-2340651-A1 (CA)
Inventor: WARAM THOMAS C
IPC: A61F2/90
Filed: 1999-08-20
Abstract: A stent radially expandable from a radially contracted introduction state into a radially expanded position state, in which the final shape of the stent can be controlled by varying the amount and places photo-thermal energy is projected onto the interior surfaces of the tubes from which the stent is fabricated.
Patent CA-2347521-A1 (CA)
Title: Method for producing chiral carboxylic acids from nitriles with the assistance of a nitrilase or microorganisms which contain a gene for the nitrilase
Inventor: RESS-LOSCHKE MARION
IPC: C12P41/00
Filed: 1999-10-13
Abstract: The invention relates to nucleic acid sequences which code for a polypeptide with nitrilase activity, to nucleic acid constructs containing the nucleic acid sequences, and to vectors containing the nucleic acid sequences or the nucleic acid constructs. The invention also relates to amino acid sequences which are coded by the nucleic acid sequences, and to microorganisms containing the nucleic acid sequences, the nucleic acid constructs or vectors containing the nucleic acid sequences or the nucleic acid constructs. In addition, the invention relates to a method for producing chiral carboxylic acids from the racemic nitriles.
Patent CA-2348622-A1 (CA)
Title: Partial retrieval of images in the compressed domain
Inventor: CHRISTOPOULUS CHARILAOS
IPC: H04N1/41
Filed: 1999-10-13
Abstract: In a method and a system for retrieving images in a client-server system, images are stored as a set of independently decodable units (CU's) on the server. A client issues a series of requests for image information. Each request contains a request number, information on what image information the client wants to see next and information on what image information the client had received at the time when the request was issued. The server does not have to store any state information (e.g. previous requests). On receiving a request, the server sends a restart marker, a confirmation of the request number and incremental image information corresponding to the request. The use of the method and the system as described herein will result in that no decoding of the whole bit stream will be required in the server. This will save a lot of time at the sender side (server side), since it does not need a full decoding of the stream.
Patent CA-2351101-A1 (CA)
Inventor: WATT KENNETH R
IPC: B05B3/02
Filed: 2001-06-18
Abstract: Apparatus and method for spray coating of a horizontally moving web uses a spray-down unit that sprays downwardly onto the web and a spray-up unit that sprays upwardly onto the web. Each unit has adjustable cut-offs that control the length of the spray pattern by intercepting end portions of the spray pattern. The cut-offs of each unit can be adjusted to block a spray emission opening so as to prevent the entrance of contaminants when the unit is not in operation. Fluid intercepted by the cut-offs is returned for re-use. Both units are supported on a frame, and the spray-down unit can be moved away from the spray-up unit.
Patent CA-2351341-A1 (CA)
Title: Collagen hemostatic foam
Inventor: MADDALO FRANCIS B
IPC: A61P17/02
Filed: 1999-12-06
Abstract: A hemostatic device formed of collagen particles and methods for producing and using the hemostatic device to control bleeding are provided. The collagen particles of the hemostatic device have a hemostatic activity that is equivalent to the hemostatic activity of the collagen particles from which the hemostatic device is formed. More preferably, the hemostatic devices are formed of Avitene®; flour and the collagen particles of the hemostatic devices of the invention have a hemostatic activity equivalent to the hemostatic activity of Avitene®; flour. The hemostatic devices optionally include hemostatic agents and/or therapeutic agents, to farther promote hemostasis and wound healing.
Patent CA-2351627-A1 (CA)
Title: Methods and compositions for diagnosis and treatment of cancer based on the transcription factor ets2
Inventor: WATSON DENNIS K
IPC: A61K48/00
Filed: 1999-11-23
Abstract: The present invention relates to methods for treating and preventing cancer by modifying the expression of ets2 gene expression or the activity of the gene product. The invention also relates to sensitizing cancer cells to chemotherapeutic or radiotherapeutic agents. Ets2 gene expression and/or activity of the gene product can be modulated using antisense ets2 nucleic acids and/or modified ets2 proteins. The present invention also provides pharmaceutical compositions which comprise antisense ets2 nucleic acid, and nucleic acid that encode modified ets2 proteins and/or modified ets2 proteins.
Patent CA-2351650-A1 (CA)
Title: Laundry machine
Inventor: MCGILL IAN CAMPBELL
IPC: D06F39/08
Filed: 1999-11-17
Abstract: A laundry washing machine having a drain pump operating regime where the pump is turned off briefly at periodic intervals to minimise blocking. The pump may be powered by a variable frequency, variable duty cycle drive to minimise the effects of ventilation and varying main supply voltage. The spin tub is braked by dumping the electrical energy regenerated by the main motor into the inductive winding of an ancillary motor, such as a pump motor, or of a solenoid valve. A  method of powering on and off a laundry washing machine and an optocoupler drive circuit are also disclosed.
Patent CA-2351978-A1 (CA)
Title: Drilling direction control device
Inventor: DAVIES EVAN L
IPC: E21B7/08
Filed: 2001-06-28
Abstract: A drilling shaft deflection assembly for a drilling direction control device of the type comprising a rotatable drilling shaft and a housing for supporting a length of the drilling shaft for rotation therein. The deflection assembly is contained within the housing and is axially located between a first support location and a second support location for bending the drilling shaft between the first support location and the second support location. The deflection assembly includes a deflection mechanism for imparting lateral movement to the drilling shaft to bend the drilling shaft, a deflection actuator for actuating the deflection mechanism in response to longitudinal movement of the deflection actuator, and a deflection linkage mechanism between the deflection mechanism and the deflection actuator for converting longitudinal movement of the deflection actuator to lateral movement of the drilling shaft.
Patent CA-2352621-A1 (CA)
Inventor: BARROUX CLAIRE
IPC: G01N33/28
Filed: 2001-07-09
Abstract: - Méthode utilisant une modélisation de type « Black Oil » pour prédire en fonction du temps la composition détaillée de fluides produits par un gisement souterrai n en cours de production, combinée avec une étape d'éclatement ou « delumping » permettant une représentation thermodynamique détaillée des fluides de gisement. - Comme données d'entrée pour le modèle, on introduit non seulement les paramètres thermodynamiques des fluides tels que viscosité, facteur de volume, densité,  rapport de dissolution gaz-huile, etc. (sous forme de tables, et/ou par corrélation, comme fonction de la pression, de la température si celle-ci varie) et, le cas échéant un paramètre additionnel conservant une mémoire de la composition du gaz tel par exemple que la densité du gaz), mais également des données concernant les variations en fonction des mêmes « abscisses », des paramètres de phase nécessaires au « delumping », sans que ceux-ci soient utilisés durant la simulation « Black Oil » des écoulements. - Application par exemple à l'établissement de profils prévisionnels de la composition détaillée des hydrocarbures produits par un gisement.
Patent CA-2357988-A1 (CA)
Title: Topology discovery in optical wdm networks
Inventor: DANG CUONG TU
IPC: H04B10/07
Filed: 2001-09-27
Abstract: In an optical WDM network, each optical channel is modulated with a respective channel identity. Detectors, conveniently at multiplex ports of optical band filters, detect the channel identities of all of the optical channels in an optical signal at the respective points to produce respective channel lists. A network management system determines channel lists for through ports of the optical band filters, identifies matching pairs of channel lists to determine a topology of each node and to identify optical paths entering or leaving each node, and identifies matching pairs of channel lists for these paths to determine an internode topology of the network. The channel identity detector points can alternatively be at the optical paths entering or leaving each node.
Patent CA-2358909-A1 (CA)
Title: Metal-flake manufacturing apparatus
Inventor: YOSHIZAWA HIROKI
IPC: B22F1/062
Filed: 2000-11-02
Abstract: Cooling rolls (11) and (12) are spaced to have a gas of a size greater than thickness of metal thin bodies to be produced. A nozzle (14) is arranged to eject molten metal onto a surface of the cooling roll (11). The first cooling roll (11) quenches molten metal ejected from the nozzle (14) into metal thin bodies. On the next cooling roll (12), the produced metal thin bodies are hit into flakes and excessive molten metal is made into metal thin bodies.     Thus, freedom of supplying the molten metal is enhanced and metal flakes can be efficiently produced.
Patent CA-2366791-A1 (CA)
Title: Pharmaceutical dosage form for pulsatile delivery of d-threo-methylphenidate and a second cns stimulant
Inventor: TEICHER MARTIN
IPC: A61P25/28
Filed: 2000-04-06
Abstract: Novel pharmaceutical dosage forms provide for pulsatile delivery of d-threo- methylphenidate and a second CNS stimulant, i.e., release encapsulated drug in spaced apart "pulses". The second CNS stimulant may be an analeptic agent or  a psychostimulant, with analeptic agents preferred. The dosage forms may comprise capsules housing compressed tablets or drug-containing beads or particles, or may comprise a tablet with the first, second and optionally third dosage units each representing an integral and discrete segment thereo f. Methods of treatment using the pharmaceutical dosage forms are provided as well.