baber/WOPTO huggingface dataset:
Patent AU-2016222396-A1 (AU)
Title: Pyrazine derivatives useful as inhibitors of ATR kinase
Inventor: CHARRIER JEAN-DAMIEN
IPC: C07D409/14
Filed: 2016-08-31
Abstract: The present invention relates to pyrazine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula (I): wherein the variables are as defined herein. N (L)n-R'
Patent AU-2016231514-A1 (AU)
Title: Patient interface for ophthalmologic diagnostic and interventional procedures
Inventor: GOODING PHILLIP
IPC: A61F9/009
Filed: 2016-09-21
Abstract: Docun t5-I19/09/2016 One embodiment is directed to a patient interface system for ophthalmic intervention on an eye of a patient, comprising: a housing; an optical lens coupled to the housing and having an optical axis; a eye surface engagement assembly coupled to the housing and comprising an inner seal having an inner seal diameter and being configured to circumferentially engage the eye, an outer seal having an outer seal diameter and being configured to circumferentially engage the eye, and a tissue migration bolster structure configured to be positioned circumferentially between the inner and outer circumferential seals and to prevent migration of tissue of the eye toward the eye surface engagement assembly when a vacuum load is applied within the assembly to cause vacuum engagement of the inner and outer seals against the eye.
Patent AU-2016247724-A1 (AU)
Title: Device for assembling a battery element with the cartridge, with which it is associated, of an electronic cigarette
Inventor: CAI THIERRY
IPC: A24F40/70
Filed: 2016-04-08
Abstract: The subject of the invention is a device for assembling an electronic cigarette (10) comprising a shell (15) containing electrical power supply means and a cartridge (12) that can be detached from the shell (15) of the electronic cigarette. The cartridge comprises at least one pin (14) projecting from the external wall of that end (13) of the cartridge (12) that is intended for assembling the cartridge (12) with the shell (15) of the cigarette, and an assembly ring (11) in which this end (13) becomes inserted, said ring (11) being placed inside the shell (15), at one end thereof, and configured to constitute the female socket of a bayonet assembly mechanism of which the end (13) of the pipe (12) forms the male part. The ring (11) comprises locking means (41, 42) which are configured to keep the pin (14) in a locking position (23) in the absence of user action when the cartridge (12) is being assembled with the shell (13).
Patent AU-2016256681-A1 (AU)
Title: Normalized probability of change algorithm for image processing
Inventor: KLEIN ROBERT JAMES
IPC: G06T1/00
Filed: 2016-11-08
Abstract: NORMALIZED PROBABILITY OF CHANGE ALGORITHM FOR IMAGE A method for detecting changes in geospatial imagery. An imaging device is operated to take two images of a single location. The two images are received at processor (1004), which normalizes the visible band and near infrared band of the two images. The two images are registered. Corresponding pixels of the two images are divided into a first group with slope and a second group without slope. Slope groupings are compared to determine which corresponding pixels have a probability of change greater than a predetermined threshold. Vector polygons are created based on the comparing slope groupings, to indicate areas of change in the two images. The areas of change in the two images are displayed on a display device (912).
Patent AU-2016271124-A1 (AU)
Title: De-immunized, Shiga toxin a subunit scaffolds and cell-targeting molecules comprising the same
Inventor: POMA ERIC
IPC: C07K14/25
Filed: 2016-05-27
Abstract: The present invention relates to Shiga toxin A Subunit derived polypeptides and cell-targeting molecules comprising amino acid substitutions which equip the polypeptides with 1) de-immunization; 2) reduced, protease-cleavage sensitivity; and/or 3) a heterologous epitope cargo(s) while retaining Shiga toxin function(s), such as, e.g., potent cytotoxicity. Certain polypeptides of the invention exhibit reduced immunogenic potential in mammals and/or are capable of delivering an epitope to an MHC class molecule of a cell in which the polypeptide is present. Certain molecules comprising a polypeptide of the invention are well-tolerated by mammals while retaining one or more of the features mentioned above. The Shiga toxin polypeptides of the invention have uses as components of cell-targeting molecules for selectively killing specific cells; for selectively delivering cargos to specific cells, and as therapeutic and/or diagnostic molecules for treating and diagnosing a variety of conditions, including cancers, immune disorders, and microbial infections.
Patent AU-2016271762-A1 (AU)
Title: Nitrogen-containing tricyclic derivative having HIV replication inhibitory activity
Inventor: TAMURA YOSHINORI
IPC: C07D487/06
Filed: 2016-05-27
Abstract: Provided are: a novel compound having antiviral action, especially HIV replication inhibitory activity; and a pharmaceutical product, especially an anti-HIV agent which contains this compound. A compound represented by formula (I). (In the formula, A
Patent AU-2016285730-A1 (AU)
Title: Modular suitcase frame
Inventor: SCICLUNA PAUL V
IPC: A45C13/04
Filed: 2016-06-29
Abstract: A piece of luggage comprises a front shell, a rear shell, and a frame assembly configured to hingedly secure the front shell to the rear shell. The frame assembly including a front frame sub-assembly configured to be secured to the front shell and a rear frame sub-assembly configured to be secured to the rear shell. Each of the front frame sub-assembly and the rear frame sub-assembly including a plurality of frame members and a plurality of corner members.
Patent AU-2016303550-A1 (AU)
Title: Combination treatments and uses and methods thereof
Inventor: HOOS AXEL
IPC: C07K16/28
Filed: 2016-08-03
Abstract: The present invention provides methods of treating cancer in a human in need thereof comprising administering to the human: a therapeutically effective amount of a monoclonal antibody that binds to human OX40 comprising: (a) a heavy chain variable region CDR1 comprising the amino acid sequence of SEQ ID NO:1; (b) a heavy chain variable region CDR2 comprising the amino acid sequence of SEQ ID NO:2; (c) a heavy chain variable region CDR3 comprising the amino acid sequence of SEQ ID NO:3; (d) a light chain variable region CDR1 comprising the amino acid sequence of SEQ ID NO:7; (e) a light chain variable region CDR2 comprising the amino acid sequence of SEQ ID NO:8; and (f) a light chain variable region CDR3 comprising the amino acid sequence of SEQ ID NO:9; and a therapeutically effective amount of a monoclonal antibody that binds to human PD- 1 comprising: (a) a heavy chain variable region CDR1 comprising the amino acid sequence of SEQ ID NO:54; (b) a heavy chain variable region CDR2 comprising the amino acid sequence of SEQ ID NO:55; (c) a heavy chain variable region CDR3 comprising the amino acid sequence of SEQ ID NO:56; (d) a light chain variable region CDR1 comprising the amino acid sequence of SEQ ID NO:57; (e) a light chain variable region CDR2 comprising the amino acid sequence of SEQ ID NO:58; and (f) a light chain variable region CDR3 comprising the amino acid sequence of SEQ ID NO:59.
Patent AU-2016321146-A1 (AU)
Title: ApoA-1 fusion polypeptides and related compositions and methods
Inventor: HAYDEN-LEDBETTER MARTHA S
IPC: C12N9/22
Filed: 2016-09-06
Abstract: Compositions and methods relating to ApoA-1 fusion polypeptides are disclosed. The fusion polypeptides include a first polypeptide segment corresponding to an ApoA-1 polypeptide or ApoA-1 mimetic, and may also include a dimerizing domain such as, e.g., an Fc region, which is typically linked carboxyl-terminal to the first polypeptide segment via a flexible linker. In some embodiments, the fusion polypeptide further includes a second polypeptide segment located carboxyl-terminal to the first polypeptide segment and which confers a second biological activity (e.g., an RNase, paraoxonase, platelet-activating factor acetylhydrolase, cholesterol ester transfer protein, lecithin-cholesterol acyltransferase, or polypeptide that specifically binds to amyloid beta). Also disclosed are dimeric proteins comprising first and second ApoA-1 fusion polypeptides as disclosed herein. The fusion polypeptides and dimeric proteins are useful in methods for therapy.
Patent AU-2016341089-A1 (AU)
Title: Composition comprising an oil phase
Inventor: FLENDRIG LEONARDUS MARCUS
IPC: A23D7/005
Filed: 2016-10-18
Abstract: The present invention relates to a composition comprising an oil phase, and particles of puffed endosperm of a puffable seed, dispersed in said oil phase, wherein upon sieving at least 80 wt% of said particles passes a sieve with apertures of 500 µm. The invention also provides a method to prepare such compositions and use of particles of puffed endosperm to structure the oil phase of a composition comprising an oil phase.
Patent AU-2016342463-A1 (AU)
Title: Cooling storage container in phases
Inventor: PITSINKI ARTO
IPC: F17C9/02
Filed: 2016-10-13
Abstract: A storage container in a current temperature is cooled to a target temperature in two phases comprising a first phase of convective heat transfer from the storage container to dry ice, and a second phase of flowing sublimed dry ice to the storage container. Deviation of the current temperature from the target temperature is measured. The first phase is applied, when the deviation of the current temperature inside the storage container is higher than a threshold value for the deviation. The second phase is applied, when the deviation of current temperature inside the storage container is less than a threshold value.
Patent AU-2016355125-A1 (AU)
Title: Power manager with reconfigurable power converting circuits
Inventor: LONG DAVID
IPC: H02J1/04
Filed: 2016-10-26
Abstract: A portable power manager device (100) includes a DC power bus (110) and a plurality of device ports (141, 142, and 143). A primary device port (143) is connectable to the DC power bus over a primary power channel that does not include a DC to DC power converter. A plurality of secondary device ports (141, 142) is each connectable to the DC power bus over a different reconfigurable power channel (151, 152). Each reconfigurable power channel includes a single one-way DC to DC power converter (220, 221). Each reconfigurable power channel is configurable by a digital data processor as one of three different circuit legs (230, 232, and 234). Leg (230) provides output power conversion. Leg (232) provides input power conversion. Leg (234) provides bi-directional power exchange without power conversion.
Patent AU-2016355911-A1 (AU)
Title: Interactive golfing system and method
Inventor: SEYMOUR DANIEL WALTER
IPC: A63B57/00
Filed: 2016-11-18
Abstract: A system and a computer-implemented method are disclosed. The method comprises the steps of: receiving, from a golfer mobile device, a request to conduct a round of golf, the request comprising round information and identification of a validator mobile device, receiving, from the validator mobile device, confirmation of validator status, receiving, from the golfer mobile device, score data and location data of the golfer mobile device. The method further comprises receiving, from the validator mobile device, location data of the validator mobile device, determining whether the received score data is valid by comparing the location data of the golfer mobile device to the location data of the validator mobile device, and determining and recording a score based on the score data for the golfer if the received score data is determined to be valid.
Patent AU-2016412622-A1 (AU)
Title: System and method for managing product usage from dispensers
Inventor: GHAZI BABAK R
IPC: G06Q50/10
Filed: 2016-06-28
Abstract: A system and method are provided for improving product usage prior to refill of product dispensers in service areas that include a plurality of such dispensers. Via a sensor configured with each of the product dispensers and a control system in communication with the sensors, a product level or amount condition of product in each dispenser is detected. Based on the information from the sensors, a visual or audio message is generated and transmitted to the patron that encourages the patron to use a first product dispenser that has a greater product fill amount as compared to a second product dispenser in the same or a different service area.
Patent AU-2016428280-A1 (AU)
Title: Drive device and air-conditioner, and compressor control method
Inventor: NIGO MASAHIRO
IPC: H02P1/32
Filed: 2016-10-31
Abstract: This drive device (100a) is used together with a rotary compressor (8) provided with an electric motor (1) having a coil (3), and drives the electric motor (1). The drive device (100a) comprises: an inverter (103); a connection switching unit (60) which switches the connection state of the coil (3) between a first connection state and a second connection state; a control device (50) which controls the inverter (103) and the connection switching unit (60); and a compressor temperature sensor (71) which detects the state of the rotary compressor (8). When the connection state of the coil (3) is the first connection state, the control device (50 controls the electric motor (1) on the basis of a first threshold value and a first detection value detected by the compressor temperature sensor (71). When the connection state of the coil (3) is the second connection state, the control device (50) controls the electric motor (1) on the basis of a second threshold value and a second detection value detected by the compressor temperature sensor (71).
Patent AU-2016430233-A1 (AU)
Title: Filter system
Inventor: HALES ERIC
IPC: B01J8/00
Filed: 2016-12-22
Abstract: A system for filtering water in a spa that provides safety and greater filtration. The system may include a filter secured to a core. The core may include first and second cages with a plurality of openings allowing water to freely pass through the filter and core while preventing larger objects from passing through. The first cage may provide an orientation feature to position the filter in one direction. The second cage may hold mineral cartridges. The core may be secured to a fitting that is secured to the suction line of a spa via a ratchet like engagement feature. The fitting and core prevent back out of the core unless manually overriding the arm on the core which engages fins on the fitting. The filter may be removed and replaced while the core remains in place providing safety to the user. A cap secures the whole assembly into place.
Patent WO-2017201568-A1 (WO)
Title: Média numérique ancré dans l'emplacement d'étiquettes média pour des environnements de réalité virtuelle et de réalité augmentée
Inventor: MARTIN PAUL SIMON
IPC: G06F17/30
Filed: 2017-05-19
Abstract: La présente invention concerne un procédé consistant à créer un média numérique, consistant à le placer le média numérique dans un environnement graphique informatique, l'environnement de graphique informatique comprenant également les éléments visibles apparaissant comme des objets réels placés dans un paramètre de monde réel, et visualisant le média numérique dans le paramètre de monde réel. Divers systèmes illustratifs comprennent un serveur de réalité virtuelle et de réalité augmentée connecté à un réseau, et un dispositif client connecté au réseau, le dispositif client possédant une application de réalité virtuelle et de réalité augmentée. D'autres systèmes illustratifs comprennent un capteur de corps ou de mouvement connecté au dispositif client, et/ou une interface de réalité virtuelle et de réalité augmentée connectée au dispositif client.
Patent WO-2018107245-A1 (WO)
Title: Détection de conditions environnementales
Inventor: CLARK ANTHONY
IPC: G06Q50/02
Filed: 2017-12-15
Abstract: La présente invention concerne un système de surveillance environnementale (1) et un procédé (100) pour détecter une condition environnementale d'une zone spécifiée (3). Le système (1) comprend un ou plusieurs capteurs à distance (4) et/ou une source de données climatiques (9) pour fournir des données de capteur indiquant une teneur en eau du sol, une croissance de plantes et une hauteur de pluie associées à la zone spécifiée. Un dispositif de traitement (13) est configuré pour : déterminer (110) une teneur en eau du sol, une croissance de plantes et une hauteur de pluie sur la base de données de capteur et de données historiques; déterminer (120) une direction de sécheresse associée à la zone spécifiée (3) qui indique une tendance de précipitation; et déterminer (130) des indicateurs pour la teneur en eau du sol, la croissance de plantes et la hauteur de pluie pendant des conditions de sécheresse et des conditions normales. Le dispositif de traitement détermine en outre une condition environnementale sur la base : (i) de la direction de la sécheresse; et (ii) de la teneur en eau du sol, de la croissance de plantes et de la hauteur de pluie déterminées avec les indicateurs respectifs déterminés. Sur la base de la condition environnementale déterminée, une notification qui indique la condition environnementale est envoyée (140).
Patent AU-2017200110-A1 (AU)
Title: Mixed flow axial fan assembly
Inventor: CHU RENZHEN
IPC: F04D3/00
Filed: 2017-01-06
Abstract: Abstract The utility model provides a mixed flow axial fan assembly, comprising an axial fan and a skeleton bustle pipe, wherein the axial fan is mounted in the skeleton bustle pipe, the skeleton bustle pipe is a mixed flow bustle pipe, the mixed flow bustle pipe comprising a flow-guide pressurized area and an air flow spreading area used for discharging air, the air flow spreading area being located in a downstream of the flow-guide pressurized area, and the air flow spreading area comprising a circumferential air discharging area and an axial air discharging area. The advantages of the utility model are that the bustle pipe uses a skeleton support structure, not only satisfying the strength requirement for hoisting the axial fan but also changing an air flow direction blown from the axial fan by means of flow-guide pressurization below the bustle pipe and a spreading structure above the bustle pipe; and the axial fan not only discharges air in the vertical direction but also discharges air all around, forming an air blowing effect of mixed flow air. The utility model breaks through the mode that a traditionally mounted axial fan can only intake air and discharge air in the same direction.
Patent AU-2017201434-A1 (AU)
Title: Trampoline levelling apparatus
Inventor: ANDON JOE
IPC: A63B5/00
Filed: 2017-03-02
Abstract: Trampoline levelling apparatus for levelling a trampoline including a frame and a plurality of legs that are adapted to both engage a foundation and space said frame above the foundation, said trampoline levelling apparatus including: a threaded rod, a longitudinal axis extending through the threaded rod, an upper end and a lower end; a head on the upper end of the threaded rod adapted for engagement with a driver for rotation of the threaded rod about the longitudinal axis; a knob on the lower end of the threaded rod; a foot having a base plate and a receptacle in which the knob is received and captured; a threaded sleeve for engagement with the threaded rod; and a clamp assembly mounted to the threaded sleeve; the parts being so formed and arranged that the threaded rod may be turned about its axis whilst captured in the receptacle of the foot by its knob. Fig. 1 Fig. 13 Fig. 14
Patent AU-2017201578-A1 (AU)
Title: Multiuse, enzymatic detergent and methods of stabilizing a use solution
Inventor: CHAN WENDY
IPC: C11D7/02
Filed: 2017-03-08
Abstract: Abstract Stabilized use solutions of low phosphorus, alkali metal carbonate detergents employing enzymes for cleaning compositions are disclosed. In particular, the present invention is a composition for, and method of, removing soils, preventing redeposition of protein soils and reducing foam, using stabilized enzyme cleaning compositions, namely use solutions of the same.
Patent AU-2017205024-A1 (AU)
Title: Anti-Her2 combinations for treating tumors
Inventor: LI LIXIN
IPC: A61P37/04
Filed: 2017-01-06
Abstract: A combination which comprises an effective amount of Her2/Neu antagonist and an effective amount of immunotherapeutic that is capable of activating a human plasmacytoid dendritic cell, myeloid dendritic cell, NK cell, or a combination thereof is disclosed.
Patent AU-2017206214-A1 (AU)
Title: Safety post rammer and safe post
Inventor: REARDON HERBERT MERVYN
IPC: E04H17/00
Filed: 2017-07-20
Abstract: A safer hand-operated driver for driving posts into the soil has a fixed shield or skirt about the lower end to keep the operator's hands apart from the upper end of the post if it escapes from within the driver. As a second safety measure, each fence post may bear a contrasting colour over the top of each post. The operator can see the coloured region and does not lift the driver any higher than required, through viewing apertures that reveal the post immediately above the free edge of the skirt. 105 300 303 F Fig3 Fg
Patent AU-2017229365-A1 (AU)
Title: Small molecule inducers of reactive oxygen species and inhibitors of mitochondrial activity
Inventor: NEAMATI NOURI
IPC: C07D215/02
Filed: 2017-03-07
Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazolinedione structure which function as reactive oxygen species (ROS) inducers and inhibitors of mitochondrial activity within cancer cells (e.g., pancreatic cancer cells), and their use as therapeutics for the treatment of cancer (e.g., pancreatic cancer) and other diseases.
Patent AU-2017231580-A1 (AU)
Title: Double tubular structures
Inventor: VULTO PAUL
IPC: B01L3/00
Filed: 2017-03-09
Abstract: The present invention relates to a method of culturing and/or monitoring epithelial cells using a microfluidic cell culture system comprising a microfluidic channel network. In the method epithelial cells are lined, in the microfluidic cell culture system by cells of mesenchymal origin. The cells may form a tubular or tube-like structure, i.e. a.tube in a tube. The method allows for improved epithelial models suitable for a wide variety of applications, including but not limited to high-throughput screening and analysis of epithelium in health and disease.
Patent AU-2017251253-A1 (AU)
Title: Novel bacterial species
Inventor: DE VOS WILLEM MEINDERT
IPC: C12N1/20
Filed: 2017-04-11
Abstract: A novel Akkermansia species has been isolated from fresh faeces obtained from the reticulated python. The species has been named Akkermansia glycaniphilus. It is capable of growing on mucus as a sole carbon and nitrogen source. The species can be used as a medicament, probiotic or cosmetic, e.g., for promoting weight loss, for promoting gut mucosal immune system function, for maintaining, restoring and/or increasing the physical integrity of the gut mucosal barrier, and for prevention or treatment of a variety of associated diseases or disorders.
Patent AU-2017258301-A1 (AU)
Title: Electrotherapeutic treatment
Inventor: HAZELWOOD VIKKI
IPC: A61B8/00
Filed: 2017-04-27
Abstract: Systems and methods for locating, assessing, diagnosing, treating and monitoring of musculoskeletal disorders, soft tissue injuries, pain and other areas of dysfunctional tissue in patients, are provided. In the systems and methods, such assessments and treatments are performed using a combination of electrical stimulation and imaging tools.