baber/WOPTO huggingface dataset:
Patent TW-I733577-B (TW)
Title: Real-time tool image identification system
Inventor: JYWE WEN-YUH
IPC: B23Q15/00
Filed: 2020-09-02
Granted: 2021-07-11
Abstract: The utility model relates to a real-time tool image identification system, which comprises an IoT Router, a spindle camera, and a controller connected to the IoT Router separately, and the controller is installed in a machine tool. The spindle camera takes the knife holder and the tool image installed on the machine tool host as the spindle tool image, and there is a cloud platform connected with the IoT Router signal. It is used to receive the spindle tool image and the equipment tool data provided by the controller, and the real-time tool image identification system of the client platform analyzes and processes the spindle tool image and compares it with the obtained equipment tool data. if there is a discrepancy, the controller is controlled through the IoT Router to make the machine tool send an alarm and stop, avoid using wrong or inappropriate tools during machining, and improve the quality of processing. Avoid tool and equipment failure.
Patent TW-I780509-B (TW)
Title: 秧苗移植機
Inventor: MIZUNO YOSHINORI
IPC: A01C11/02
Filed: 2020-10-30
Granted: 2022-10-11
Abstract: 提供秧苗移植機，在反復進行行駛和迴轉並在田地插植秧苗的情況下，從一開始就能夠將下次進行秧苗插植的行的一側的劃線器切換為作用姿勢，操作性良好。秧苗移植機具有：行駛車輛；秧苗插植部，安裝於行駛車輛的後部，具有插植裝置；左右一對劃線器，設置於行駛車輛或秧苗插植部，一對劃線器具有劃線體，該劃線體在田地上形成表示行駛車輛行駛的位置的線；姿勢切換單元，能夠將一對劃線器在作用姿勢與非作用姿勢之間進行切換；以及操作部，能夠操作姿勢切換單元，姿勢切換單元構成為，能夠左右獨立地將一對劃線器從非作用姿勢切換為作用姿勢，並且，能夠將一對劃線器同時從作用姿勢切換為非作用姿勢。
Patent TW-I758931-B (TW)
Title: 加壓缸裝置
Inventor: CAI HONG-LI
IPC: F16J10/00
Filed: 2020-11-03
Granted: 2022-03-21
Abstract: 一種加壓缸裝置，具有一缸體，其內部形成有一傳動室，缸體之一端設有一傳動部頂座，並於傳動室中設有一可滑移之活塞，且活塞具有一加壓桿，而一油壓部底座設於缸體之另一端，油壓部底座設有一可供輸出液壓油之油壓流道、一與油壓流道相通之加壓室及一同時連通傳動室與加壓室之組設孔，而一襯套可拆卸地設置於組設孔中，襯套具有一朝向傳動室之頂面及一與頂面相反之底面，頂面露出於油壓部底座朝向該傳動室之端面，並於襯套上開設有一貫穿其頂面及底面之穿孔，穿孔與加壓桿之形狀相對應且呈同軸配置，使加壓桿可直接穿經襯套之穿孔而伸入於加壓室中。
Patent TW-I730928-B (TW)
Title: 可拆組之電動床
Inventor: SHIH CHUAN-HANG
IPC: A47C20/02
Filed: 2020-11-26
Granted: 2021-06-11
Abstract: 本發明係一種可拆組之電動床，包含有一固定架、一活動架以及一致動器。該活動架包含有二縱桿與一橫桿，該二縱桿分別與該固定架樞接，該橫桿二端分別延伸設有至少一凸柱，每一該縱桿具有至少一嵌孔，供該些凸柱伸入；該致動器以其二端分別樞設於該固定架與該橫桿，藉此，該電動床可供拆解以減縮包裝材積，同時該電動床之組裝容易，方便使用者自行組裝。
Patent TW-I756961-B (TW)
Inventor: HU HUI-WEN
IPC: F04D29/58
Filed: 2020-12-03
Granted: 2022-03-01
Abstract: A fan frame and the array thereof are disclosed. The fan frame includes a frame body with an outer frame surface and an inner frame surface, the outer frame surface is hexagonal, and the inner frame surface is circular; and a fan base connected to the frame body by a plurality of connecting elements. In this way, the fan frame's material can be reduced under the condition of providing the same flow area. Alternatively, it can increase the flow area while occupying the same physical space.
Patent TW-I795701-B (TW)
Title: 壓電元件、壓電裝置及壓電元件之製造方法
Inventor: MAWATARI KAZUAKI
IPC: B81B3/00
Filed: 2020-12-21
Granted: 2023-03-11
Abstract: 具備：支持體；和振動部，其係設為被配置在支持體上，包含壓電膜，和與壓電膜連接而取出由於壓電膜變形產生的電荷的電極膜的構成，具有被支持於支持體的支持區域，和與支持區域連接，從支持體浮動的複數振動區域，輸出根據電荷的壓力檢測訊號。設為電極膜被形成在第1區域。而且，形成提升壓電檢測訊號之檢測精度的提升部。
Patent TW-I770816-B (TW)
Title: Semiconductor device
Inventor: YAMAZAKI SHUNPEI
IPC: H01L21/28
Filed: 2013-09-12
Granted: 2022-07-11
Abstract: A semiconductor device including a capacitor whose charge capacity is increased while improving the aperture ratio is provided. Further, a semiconductor device which consumes less power is provided. A transistor which includes a light-transmitting semiconductor film, a capacitor in which a dielectric film is provided between a pair of electrodes, an insulating film which is provided over the light-transmitting semiconductor film, and a first light-transmitting conductive film which is provided over the insulating film are included. The capacitor includes the first light-transmitting conductive film which serves as one electrode, the insulating film which functions as a dielectric, and a second light-transmitting conductive film which faces the first light-transmitting conductive film with the insulating film positioned therebetween and functions as the other electrode. The second light-transmitting conductive film is formed over the same surface as the light-transmitting semiconductor film of the transistor and is a metal oxide film containing a dopant.
Patent TW-I781589-B (TW)
Inventor: CHIANG HSIN-TSO
IPC: A63F13/426
Filed: 2021-04-16
Granted: 2022-10-21
Abstract: 一種顯示方法及其顯示裝置，在顯示方法中，接收一影像。此影像具有一指示物件與一顯示背景，顯示背景環繞指示物件。接著，改變指示物件之原色為第一顏色，並根據顯示背景之部分的平均色度，顯示具有第一顏色之指示物件的影像。顯示背景之部分環繞指示物件，平均色度對應第二顏色，第一顏色與第二顏色為互補色。
Patent TW-I777502-B (TW)
Inventor: KOLAKOWSKI ROBERT
IPC: A61P35/00
Filed: 2014-12-19
Granted: 2022-09-11
Abstract: The present invention provides Ligand-Drug Conjugates and Drug-Linker Compounds comprising a methylene carbamate unit.
Patent TW-I777532-B (TW)
Title: System, computer-implemented method and apparatus for centralized status monitoring
Inventor: NANDURI SUBRAHMANYA PRAMOD
IPC: G06Q10/08
Filed: 2021-04-28
Granted: 2022-09-11
Abstract: A system for centralized status monitoring in a multidomain 
network. The system includes at least one processor and at least one memory device storing instructions that when executed configure the processor to perform operations. The operations include establishing connections with domains, receiving a first request from a first domain to initiate a monitoring operation, and generating a new entry in a status table stored in a first database. The operations also may 
include receiving a second request from the second domain to update the monitoring operation and, in response to receiving the second request, updating the new entry in the status table by modifying the status field. The operations may also include applying a monitor operation in response to receiving a third request from a monitoring engine and generating an alert comprising entries in the status table in which the status field matches the category status.
Patent TW-I780692-B (TW)
Inventor: CHOU CHENG-HSIEN
IPC: H01L27/146
Filed: 2021-05-07
Granted: 2022-10-11
Abstract: 在一些實施例中，本揭露涉及一種圖像感測器。圖像感測器包括基底。光偵測器位於基底中且包含延伸到基底的第一側中的半導體保護環。淺溝渠隔離(STI)結構延伸到基底的第一側中。外部隔離結構延伸到與基底的第一側相對的基底的第二側中到達淺溝渠隔離結構。淺溝渠隔離結構和外部隔離結構橫向包圍光偵測器。內部隔離結構延伸到基底的第二側中且上覆光偵測器。內部隔離結構通過基底與光偵測器垂直分離。此外，外部隔離結構橫向包圍內部隔離結構。
Patent TW-I813993-B (TW)
Title: 一種靈芝液態發酵液用於製備預防、改善或治療阿茲海默症或阿茲海默症引起的相關病症的組合物之用途
Inventor: CHEN WEI-JEN
IPC: A61K36/074
Filed: 2021-05-12
Granted: 2023-09-01
Abstract: 本發明提供一種靈芝液態發酵液用於製備預防、改善或治療阿茲海默症或阿茲海默症引起的相關病症的組合物之用途，其中該靈芝液態發酵液的製備方法，包括：將該靈芝菌種在液態培養基中培養，得到一種靈芝液態發酵產物，將該靈芝液態發酵產物固液分離，移除菌絲體，得到該靈芝液態發酵液。其中該預防及改善阿茲海默症是改善記憶損傷、改善焦慮狀態改變、降低腦中GFAP(Glial fibrillary acidic protein)活化、β型澱粉樣蛋白累積或降低腦組織中氧化傷害的發生。
Patent TW-I780810-B (TW)
Inventor: CHEN WEICHIA
IPC: G11C16/26
Filed: 2021-07-08
Granted: 2022-10-11
Abstract: A non-volatile memory apparatus including a non-volatile memory and a memory controller is provided. At a first temperature, the memory controller performs a read operation on the non-volatile memory by using a first reference verification voltage to obtain a failure bit count of memory cells. At a second temperature different from the first temperature, the memory controller performs the read operation on the non-volatile memory many times and adjusts the first reference verification voltage to obtain the same failure bit count. The reference verification voltage used in the read operation that the same failure bit count is obtained is a second reference verification voltage. The memory controller compares the first reference verification voltage and the second reference verification voltage to obtain a difference value thereof. In addition, a method for determining a read verification voltage of the non-volatile memory is also provided.
Patent TW-I803932-B (TW)
Inventor: LEE HSING HSUN
IPC: D04H1/04
Filed: 2021-08-10
Granted: 2023-06-01
Abstract: The application relates to the technical field of protective cloth, in particular to a high-strength protective cloth with moisture permeability and a manufacturing method thereof. The first fiber wire and the second woven wire are provided, and the moisture permeability film is respectively arranged on the surface of the wiring layer formed by the first fiber wire and the surface of the wiring layer formed by the second fiber wire; The first fiber wire and the second fiber wire are combined in pairs and interlaced to form laminated bonding, and the first fiber wire and the second fiber wire with the moisture permeable film are arranged as two opposite surface layers of the laminated bonding, so that the laminated bonding forms a corresponding moisture permeable film. The application provides a protective cloth with excellent moisture permeability and high strength protection performance at a high level, and achieves the best moisture permeability of the protective cloth.
Patent TW-I786774-B (TW)
Inventor: WANG CHI-CHANG
IPC: G02B11/30
Filed: 2021-08-19
Granted: 2022-12-11
Abstract: 本發明為一種成像透鏡組，由物側至像側依序包含： 光圈；第一透鏡，具有正屈折力；第二透鏡，具有負屈折力；第三透鏡，具有正屈折力；第四透鏡，具有正屈折力；以及第五透鏡，具有負屈折力；其中該成像透鏡組中最大視角的一半為HFOV，該第五透鏡的物側表面的曲率半徑R9，該成像透鏡組的整體焦距為f，並滿足下列條件：-79.81 ＜ HFOV*R9/f ＜ -38.47。
Patent TW-I805038-B (TW)
Title: Holographic microscope and using method thereof
Inventor: CHANG WEI-KANG
IPC: G02B21/06
Filed: 2021-10-21
Granted: 2023-06-11
Abstract: A holographic microscope adapted to observe the sample is provided. The holographic microscope includes a light source, a light splitting element, a polarizing element, a phase modulation element, a light combining element and a photosensitive element. The light source is adapted to provide an illumination beam. The illuminating beam is transmitted through the light splitting element to form a first light beam and a second light beam, and the sample is arranged on the transmission path of the first light beam. The polarizing element and the phase modulation element are arranged on the transmission path of the first light beam or the second light beam. The first light beam and the second light beam are transmitted to the light combining element to form an interference beam. The photosensitive element is arranged on the transmission path of the interference beam to receive the interference beam to generate an optical signal.
Patent TW-I776742-B (TW)
Title: System for analyzing user behavior in information exchange platform
Inventor: TING-CHEN LIN
IPC: G06Q30/02
Filed: 2021-11-29
Granted: 2022-09-01
Abstract: A system for analyzing user behavior in an information exchange platform is disclosed. The system includes a platform monitoring module, an online time analysis module, a consumption behavior analysis module, a data grouping module, an analysis result processing module, and a data labeling module. The online time analysis module analyzes the user online time period, the consumer behavior analysis module looks for customer unit price and average discounts, the data grouping module performs grouping for users, and the data labeling module marks the characteristics of each digital footprint. The merchants of this system can obtain information that is very close to the consumer market, so as to carry out precise marketing.
Patent TW-I792741-B (TW)
Title: 逐漸逼近暫存器式類比數位轉換裝置與訊號轉換方法
Inventor: YANG JUN
IPC: H03M1/38
Filed: 2021-12-03
Granted: 2023-02-11
Abstract: 逐漸逼近暫存器式類比數位轉換裝置包含第一與第二數位類比轉換器(DAC)電路、比較器電路、控制器電路以及動態元件匹配電路。第一與第二DAC電路取樣一輸入訊號。比較器電路與控制器電路根據第一與第二DAC電路之輸出產生多個第一與第二位元。動態元件匹配電路編碼第一位元以產生第三位元，以刷新第一DAC電路。在第一DAC電路刷新後，控制器電路更重置第二位元中之部分位元。在部分位元重置後，比較器電路根據第一與第二DAC電路之輸出產生多個比較結果。控制器電路根據比較結果產生多個第四位元，並根據該些第一、第二以及第四位元產生數位輸出。
Patent TW-I796887-B (TW)
Title: Graphic resource allocation method and graphic resource allocation system
Inventor: CHEN KUAN-JU
IPC: G06T15/00
Filed: 2021-12-21
Granted: 2023-03-21
Abstract: A graphic resource allocation method and a graphic resource allocation system are disclosed. The method includes: establishing an inference model according to first type description information and second type description information, wherein the first type description information includes description information related to graphic interface module suitable for being installed in a user equipment, and the second type description information includes description information related to graphic driving module suitable for being installing in a remote equipment; generating matching information by the inference model according to description information related to a target graphic interface module of a target user equipment, wherein the matching information is used for matching the target user equipment with a target remote equipment; and instructing the target user equipment to corporate with the target remote equipment to perform a remote computer graphic.
Patent TW-I790082-B (TW)
Inventor: LU CHI-JEAN
IPC: B65D85/808
Filed: 2022-01-04
Granted: 2023-01-11
Abstract: A tea bag is provided. The tea bag comprises a support member, a sealing film, a telescopic filter and a telescopic rope body. The support member is provided with a first opening. The sealing film is detachably arranged onto a first surface of the support member. The telescopic filter has a second opening and an accommodating space. The telescopic filter is fixed on a second surface of the support member corresponding to the position of the first opening. A brewing substance is arranged in the accommodating space, and the brewing substance includes American ginseng and red oolong tea.
Patent TW-I787055-B (TW)
Title: Package device, memory device, and semiconductor device
Inventor: LEE CHUN-LU
IPC: H01L23/60
Filed: 2022-01-12
Granted: 2022-12-11
Abstract: The present disclosure provides a package device. The package device includes a first integrated circuit chip, a second integrated circuit chip, a first input/output pin, and a first electrostatic discharge protection element. The first integrated circuit chip includes a first internal circuit and a first input/output pad disposed on the first integrated circuit chip and coupled to the first internal circuit. The second integrated circuit chip is stacked on the first integrated circuit chip. The second integrated circuit chip includes a second internal circuit and a second input/output pad disposed on the second integrated circuit chip and coupled to the second internal circuit. The first input/output pin is coupled to the first integrated circuit chip and the second integrated circuit chip.
Patent TW-I796224-B (TW)
Title: 十字弓壓箭器結構
Inventor: ZHANG ZHU-WEI
IPC: F41B5/12
Filed: 2022-05-13
Granted: 2023-03-11
Abstract: 本發明係揭露一種十字弓壓箭器結構，包括一連接座、一承載座、一滾輪、及複數彈性件。該連接座，與十字弓之擊發裝置組接，且一端延伸至十字弓之弩臂上方。該承載座，係組設於連接座面向弩臂之一端，具一座本體、一貫穿座本體形成之容槽、及一自座本體頂端凹陷形成之樞軸槽。該滾輪，對應容槽與樞軸槽容置，且局部凸出容槽外部。各彈性件，分別對滾輪兩側之軸部容置於樞軸槽，兩端分別抵接滾輪之軸部與連接座。藉由上述構件之組成，滾輪彈性對箭矢施予一預壓力，且不會對箭矢的射出動作形成干擾。
Patent TW-I814494-B (TW)
Title: 生物特徵識別軟體測試系統及方法
Inventor: YANG LI-XIN
IPC: G06F11/36
Filed: 2022-07-20
Granted: 2023-09-01
Abstract: 本發明主要揭示一種生物特徵識別軟體測試系統，其包括：   一圖像數據輸入單元、一軟體運行單元以及一測試結果輸出單元。執行軟體測試時，該圖像數據輸入單元自一數據庫單元讀出至少一個採集生物特徵圖像，並將所述採集生物特徵圖像輸入該軟體運行單元。接著，該軟體運行單元運行一生物特徵識別軟體，利用所述生物特徵識別軟體對所述採集生物特徵圖像與一預先錄製的模板生物特徵圖像進行一特徵匹配操作，藉以完成生物特徵識別，並由該測試結果輸出單元將一軟體測試結果予以輸出。
Patent TW-I812361-B (TW)
Title: 多光源照明裝置
Inventor: LEE JIA-TIAN
IPC: F21S8/04
Filed: 2022-07-21
Granted: 2023-08-11
Abstract: 一種多光源照明裝置，包括有一燈殼、一第一發光部、一控制組件、一外燈罩、一第二發光部與一安裝組件，該燈殼分設有一第一表面與第二表面，在該第一表面上裝設有該第一發光部、該控制組件與該外燈罩，該第一發光部電性連接該控制組件，該第二表面上設有一安裝槽以及平均佈設有一燈槽，該燈槽內固設該第二發光部，該安裝槽係可拆式的與該安裝組件相結合，該安裝組件係用於固定在天花板上，該第二發光部則會朝著天花板照射並經天花板反射形成間接的光源，而該第一發光部可照射天花板下方的空間。
Patent ZA-200100673-B (ZA)
Title: Variable angle spinal fixation system.
Inventor: BRACE MICHAEL
IPC: A61B17/58
Filed: 2001-01-24
Abstract: A variable angle spinal fixation system is disclosed. The system includes a longitudinal member positionable along a spinal column, a fastener having a threaded end for engaging a vertebra, and a connector member for connecting the fastener and the longitudinal member. The connector member has a channel extending through side surfaces of the connector member for receiving the longitudinal member, an opening laterally displaced from the channel and extending through top and bottom surfaces of the connector member for receiving the fastener, and a fastener clamping element for securing the fastener in the opening at a surgeon selected angle relative to the connector member and longitudinal member. The system according to the present invention allows angulation of the fastener to accommodate complex pathologies.
Patent ZA-200108540-B (ZA)
Title: Process for introducing a liquid in a fluidised bed.
Inventor: BARRACO JOSEPH
IPC: C08F2/00
Filed: 2001-10-17
Abstract: Process for the introduction of liquid into a continuous process for the gas-phase polymerization of a olefin monomer and one or more other alpha-olefins in a fluidized-bed reactor, the liquid being introduced by at least one nozzle having a feed pipe and a sleeve sliding inside and at the end of the pipe, the position of the said sleeve along the feed pipe being determined by the pressure of the feed liquid and the return force of a preloaded spring, the spring having one end fixed to the sleeve and the other end to the feed pipe, the sleeve being provided with one or more recesses along its surface for sliding with the feed pipe, the recesses emerging in a groove around the circumference of the sleeve and below a circular stop integral with the same sleeve, the stop resting, when the nozzle is not in use, on a rim of the end of the feed pipe, the rim and the circular stop of the sleeve each being provided with a bearing surface, the contact area of which is minimized to allow good sealing.
Patent ZA-200109941-B (ZA)
Title: Robust autofocus system for a microscope.
Inventor: GEUSEBROEK JAN-MARK
IPC: G02B7/28
Filed: 2001-12-03
Abstract: The present invention provides a method and apparatus for autofocusing of an optical instrument, especially a microscope (10). The autofocus scheme includes a digital gradient filter for generating a focus score from each captured image. Images may be captured at various positions and the focus scores analysed to determine a focus score maximum. The position corresponding to this maximum is then taken as the focus position. The spatial extent of the filter is preferably settable so that the digital filter settably selects elements of the image depending on their size in the image. Thus, the filtering process is controllable so that it is influenced by elements of the image whose size may be specified by the operator indirectly by way of the spatial extent of the filter. This allows the exclusion of small or large elements of the image from the autofocusing procedure which the filter should preferably ignore. The autofocus scheme is particularly useful for autofocusing biological specimens.
Patent ZA-200210268-B (ZA)
Title: Use of secretin-receptor ligands in treatment of cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD).
Inventor: DAVIS RICHARD JON
IPC: A61P11/00
Filed: 2002-12-19
Abstract: The invention describes the use of camostat in the manufacture of a medicament for the treatment of cystic fibrosis or chronic obstructive pulmonary disease.
Patent ZA-200300883-B (ZA)
Title: Compounds acting as melanocortin receptor ligands.
Inventor: LUNDSTEDT TORBJOERN
IPC: A61K45/00
Filed: 2003-01-31
Abstract: The present invention provides novel compounds and use of compounds of general formula (I) as ligands to the melanocortin receptors and/or for treatment of disorders in the melanocortin system: Wherein X and Y are independently chosen from O, N, S and (CH<SUB>2</SUB>)<SUB>n</SUB>, where n is 0, 1, 2, 3, 4, or 5, or a combination of these and may contain carbon-carbon multiple bonds and branched chains as well as alicyclic and heterocyclic groups; Q is H or OH; R<SUB>1 </SUB>and R<SUB>2 </SUB>can be either the same or different and are chosen from hydrogen or the residue of an aromatic group as listed in Scheme 1 and the pharmacologically active salts thereof
Patent ZA-200306566-B (ZA)
Title: Method and apparatus for foam casting using three-dimensional molds.
Inventor: GEORGE JONATHAN
IPC: D21F11/00
Filed: 2003-08-22
Abstract: Disclosed is a method of producing a non-woven web of fibrous or particulate material comprising: formation of a foam slurry; deposition of that slurry onto a foraminous element having a three-dimensional mold; and formation of a web having a three-dimensional shape that is not substantially planar by removal of foam from the slurry through the foraminous element and drying the web. An apparatus therefor is also disclosed. The method may be used in production a variety of products, including automotive pleated fluid and air filters, pleated heating and/or air conditioning (HVAC) filters, shaped breathing mask filters and bacterial filters, laminated cleaning products with super-absorbent middle layers, such as a mop wipe shape to fit a cleaning mop head, and other products.
Patent ZA-200509435-B (ZA)
Title: Internal glass holder
Inventor: BO STENVALL
IPC: E06B3/54
Filed: 2004-05-21
Abstract: The fixing device comprises two clamping plates (1, 4) joined via a connection mechanism (6, 15) and is mounted in a hole (2) in the inner pane (3). One of the plates has externally accessible anchor points. The inner plate is placed against the inside of the inner pane before it is connected to the outer pane. The connection parts attached to the outer plate are engaged with those attached to the inner plate to form the anchor points. Seals are provided in the hole.
Patent ZA-200807695-B (ZA)
Title: Device and method for monitoring a thread wound on a bobbin
Inventor: ANDREAS ECKER
IPC: D05B/
Filed: 2008-09-08
Abstract: Monitoring thread wound on a bobbin in a sewing machine comprises marking the bobbin with status-defining colors, optically detecting a change in status as the bobbin rotates and analyzing the change with a logic circuit. An independent claim is also included for equipment for monitoring bobbin-wound thread in a sewing machine as above, comprising a color marking system, an optical detector and a logic circuit.
Patent ZA-200904351-B (ZA)
Title: Accessory
Inventor: MORELLO LUCY
IPC: A41F/
Filed: 2007-08-21
Abstract: Garment supporting apparatus for a breast covering garment, comprising a flexible strap and a decorative attachment member.
Patent ZA-201000094-B (ZA)
Title: Pharmaceutical compositions for the treatment of chronic heart failure comprising pyrazolopyrimidinone derivative compound
Inventor: SHIN JEE-HYUN
IPC: A61K/
Filed: 2010-01-06
Abstract: Disclosed herein is a therapeutic agent for chronic heart failure comprising, as an effective ingredient, 5-[2-propyloxy-5-(1-methyl-2-pyrrolidinyl-ethylamidosulfonyl)phenyl]-1-methyl-propyl-1,6-dihydro-7H-pyrazolo(4,3-d)pyrimidine-7-one. The compound inhibits phosphodiesterase-5 (PDE-5), which catalyzes the intracellular degradation of cyclic guanosine monophosphatase (cGMP), thereby mitigating several signs of chronic heart failure, that is, thereby preventing left ventricular dilatation, decreasing ventricular wall thinning, lowering elevated cardiac and circulating levels of atrial natriuretic peptide (ANP), and inhibiting ventricular fibrosis. Also, the compound has advantages in that it reaches the maximal plasma level in a short time, has an in vivo half-life longer than conventional PDE-5 inhibitors, allowing decreased administration frequency, and has fewer side effects, thus ensuring safety. Thus, the compound is useful as a therapeutic agent for chronic heart failure.
Patent ZA-201002583-B (ZA)
Title: Manuel razor with pivoting shaving head
Inventor: BODET HERVE
Filed: 2010-04-13
Abstract: The invention relates to a manual razor including a shaving head (10) having a attached on a handle (20), pivoting means (11, 21) between the head (10) and the handle (20) so that the head (10) can move from a use position perpendicular to the handle (20) into a stowage position parallel to the handle. In order for the razor to be easily stored while occupying as little space as possible, the blade can be pivoted without touching the blade, using a rack (21) provided on a sliding button located on the handle (20), and a toothed wheel (11) connected to the head (10), wherein the toothed wheel (11) and the rack (21) are sized and arranged to be in mutual engagement.