baber/WOPTO huggingface dataset:
Patent BR-0311732-A (BR)
Title: Proteìna de parceiro de fusão, sequência de ácido nucleico, vetor de expressão, hospedeiro, composição imunogênica, processo para a preparação de uma composição imunogênica, processo para produzir uma proteìna de fusão, uso de uma proteìna ou de uma sequência de dna, e, método para tratar um paciente que sofre de câncer
Inventor: SILVA TERESA ELISA VIRGINIA CA
IPC: C12N15/62
Filed: 2003-06-06
Abstract: "PROTEìNA DE PARCEIRO DE FUSãO, SEQUêNCIA DE áCIDO NUCLEICO, VETOR DE EXPRESSãO, HOSPEDEIRO, COMPOSIçãO IMUNOGêNICA, PROCESSO PARA A PREPARAçãO DE UMA COMPOSIçãO IMUNOGêNICA, PROCESSO PARA PRODUZIR UMA PROTEìNA DE FUSãO, USO DE UMA PROTEìNA OU DE UMA SEQuêNCIA DE DNA, E, MéTODO PARA TRATAR UM PACIENTE QUE SOFRE DE CâNCER". A presente invenção refere-se a parceiros de fusão que atuam como parceiros de fusão imunológicos, como acentuadores de expressão e, de preferência, a parceiros de fusão apresentando ambas as funções. Em particular, os parceiros de fusão contêm um assim-chamado domínio de ligação de colina, por exemplo fusões compreendendo LytA de Streptococcus pneumoniae, ou o fago pneumocócico CP1 lisosima (CPL1) em que o domínio de ligação de colina é modificado de forma a incluir um epitopo de T-auxiliar heterólogo, e são fundidos a antígenos, particularmente antígenos fracamente imunogênicos, como auto-antígenos, p. ex. antígenos específicos para tumor ou específicos para tecido. A invenção refere-se também a proteínas de fusão contendo os mesmos, a sua fabricação, a seu uso em vacinas e composições imunogênicas e a seu uso em medicamentos.
Patent BR-0312631-A (BR)
Inventor: SKANTZE TOMMY URBAN
IPC: A61K9/51
Filed: 2003-07-14
Abstract: A process for the preparation of a dispersion of crystalline nanoparticles in an aqueous medium is disclosed. Specifically, a first solution comprising a substantially water-insoluble substance in a water-miscible organic solvent is rapid mixed with an aqueous phase comprising water, and optionally a stabilizer, to form a dispersion of amorphous particles. The dispersion of amorphous particles is then sonicated for a sufficient period to form crystalline nanoparticles of the substantially water-insoluble substance. The process provides nanocrystals with a mean hydrodynamic diameter of less than 1 micron, particularly less than 300 nm, and is particularly useful for the preparation of nanocrystalline dispersions of pharmaceutical substances.
Patent BR-0313544-A (BR)
Title: Núcleo de molde de uma ferramenta de moldagem por injeção
Inventor: PLASS WERNER
IPC: A47G9/06
Filed: 2003-05-20
Abstract: "NúCLEO DE MOLDE DE UMA FERRAMENTA DE MOLDAGEM POR INJEçãO". A presente invenção refere-se a um núcleo de molde (1) de uma ferramenta de moldagem por injeção para moldar por injeção pré-formas de plástico. O núcleo de molde (1) consiste em uma manga oca, fechada em uma extremidade e possuindo um eixo geométrico central, uma superfície externa (3), uma superfície interna (4) e um tubo de resfriamento oco, posicionado no núcleo de molde (1) a uma distância da superfície interna (4) do dito núcleo e conectado aos condutos de suprimento de produto de resfriamento e condutos de drenagem de produto de resfriamento. O objetivo da invenção é aumentar o efeito de resfriamento do núcleo de molde (1) com relação aos núcleos de molde utilizados anteriormente. Para se alcançar isso, o tubo de resfriamento se estende de forma coaxial com relação ao núcleo de molde (1) quase que por todo o comprimento do último e é fornecido com uma abertura de saída (9) no lado de saída de fluxo e os sulcos de resfriamento (11) são configurados na superfície interna do núcleo de molde (1), se estendendo quase que no sentido cruzado para o eixo geométrico central (2).
Patent BR-0313747-A (BR)
Inventor: GIRARDET JEAN-LUC
IPC: C07D401/12
Filed: 2003-08-22
Abstract: Various carbonyl amides are employed in vitro and in vivo as non-nucleoside inhibitors of a reverse transcriptase, and particularly of HIV reverse transcriptase. Therefore, contemplated compounds may be employed in the treatment of HIV infected patients. Further contemplated aspects include pharmaceutical compositions comprising therapeutically effective amounts of contemplated compounds.
Patent BR-0313788-A (BR)
Title: Método para distribuir substâncias biologicamente ativas
Inventor: KOLLER STEFAN
IPC: C07D213/84
Filed: 2003-08-19
Abstract: "MéTODO PARA DISTRIBUIR SUBSTâNCIAS BIOLOGICAMENTE ATIVAS". A presente invenção refere-se a um método para a liberação controlada e/ou lenta de uma substância biologicamente ativa, que contém grupo hidroxila, sobre um substrato, compreendendo reagir a dita substância que contém grupo hidroxila subseq³entemente com um halogeneto de ácido carboxílico alifático substituído por halogênio e com uma diamina que contém pelo menos um grupo amino terciário ou uma amina aromática heterocíclica, aplicando o éster solúvel em água assim obtido sobre o substrato e, finalmente, hidrolisando o éster sobre o substrato.
Patent BR-0315687-A (BR)
Title: Veìculo a motor de duas rodas
Inventor: TSUZUKU HIROYUKI
IPC: B62J99/00
Filed: 2003-10-24
Abstract: "VEìCULO A MOTOR DE DUAS RODAS". Um veículo a motor de duas rodas tem uma armação (20b) principal curvada no sentido para baixo, um motor (1) e um purificador (26) de ar que são dispostos abaixo da armação principal (20b), e um tubo de sucção provido abaixo da armação principal (20b) em uma posição entre o motor (11) e o purificador (26) de ar. O motor (1) tem um cabeçote de cilindro com uma parte de arranjo de injetor, onde é provido um injetor (11) injetando um combustível. Um bico (11a) de injeção também é provido na parte de arranjo de injetor de tal modo que o bico de injeção está em uma posição entre o eixo geométrico de uma válvula (7) de sucção e o eixo geométrico central de um orifício (3g) de sucção e que é próxima a uma parte de extremidade no lado da válvula de sucção do orifício (3g) de sucção. O tubo de sucção e o injetor são dispostos em posições em que não interferem mutuamente. Como resultado, a interferência entre o injetor e armação principal pode ser evitada, e se impede que seja reduzido o grau de liberdade de montagem do motor em um corpo de veículo. Além disso, as características de sucção, e o rendimento do motor, são aperfeiçoados.
Patent BR-0316456-A (BR)
Title: Composição herbicida
Inventor: KOTZIAN GEORG RUEDIGER
IPC: A01N37/22
Filed: 2003-11-20
Abstract: "COMPOSIçãO HERBICIDA". A presente invenção refere-se a uma composição sinérgica herbicida compreendendo uma mistura de (a) o composto metamifop, e (b) uma quantidade sinergicamente eficaz de pelo menos um composto selecionado dos compostos do grupo mesotriona, sulcotriona, isoxaflutol, pirazoxifeno, pirazolinato, benzofenap, sulfentrazona, piraflufen-etila, beflubutamid, cafenstrol, dimetametrin, clomeprop, prometrin, cinossulfuron, triassulfuron, prossulfuron, imazossulfuron, etoxissulfuron, sulfossulfuron, iodossulfuron, tritossulfuron, mesossulfuron, trifloxissulfuron, benzobicicion, acetoclor, metolacior, S-metolaclor, piracionil e N-¢(4,6-dimetoxipirimidin-2-il)aminocarbonil!-2-(2-flúor-1-metóxi-acetó xi-n-propil)piridina-3-sulfonamida, (bentazona e trifloxissulfuron), (bentazona e etoxissulfuron), (bentazona e mesolsulfuron), (bentazona e N-¢(4,6-dimetoxiprimidin-2-il)aminocarbonil!-2-(2-flúor-1-metóxi-acetóx i-n-propil)piridina-3-sulfonamida), (simetrin e cinossulfuron), (simetrin e triassulfuron), (simetrin e prossulfuron), (simetrin e trifloxissulfuron), (simetrin e imazossulfuron), (simetrin e etoxissulfuron), (simetrin e sulfossulfuron), (simetrin e iodossulfuron), (simetrin e mesossulfuron), (simetrin e tritossulfuron), (simetrina, e N-¢(4,6-dimetoxipirimidin-2-il)aminocarbonil!-2-(2-flúor-1 -metóxi-acetóxi-n-propil)piridina-3-sulfonamida) e (clodinafop e 2,4-D), a mistura de dois componentes de metamifop com benzobiciclon sendo excluída.
Patent BR-0316707-A (BR)
Title: Sistema e método para rastrear reduções de emissão ambiental
Inventor: MCMORRIS JOHN A III
IPC: G06Q30/08
Filed: 2003-11-24
Abstract: "SISTEMA E MéTODO PARA RASTREAR REDUçõES DE EMISSãO AMBIENTAL". Um sistema para rastrear performance ambiental de um produtor de emissões ambientais e para associar reduções de emissão ambientais individuais com o produtor, para uma variedade de dados coletados, ou ambos incluem selecionar uma prática de produção do produtor e um protocolo apropriado para converter a prática de produção para uma medida de emissões ambientais. Um identificador para cada unidade que pode ser quantificada de emissões ambientais possui uma parte de seq³ência caracterizando uma sucessão de unidades, uma parte de vindima caracterizando um período de tempo para a prática de produção, uma parte de caracterização de protocolo e uma parte de referência geográfica. Tal identificador permite um rastreamento dos processos que resultaram na medida das emissões ambientais.
Patent BR-0317502-A (BR)
Inventor: WOOLF RICHARD MARK
IPC: B22F3/16
Filed: 2003-12-30
Abstract: A method of producing powder metal articles includes compacting and sintering powder metal to produce a shaped powder metal preform having at least one exposed surface to be surface densified which extends parallel to an axis of the preform between a free end and a blind end adjacent a transverse portion of the preform. The blind surface is cold worked by forcing a shaped densifying tool axially along the surface in a direction from the free end toward the blind end, and then reversing the direction of the tool toward the free end to densify a layer of the material at the exposed surface. In addition to the blind surface, the article can include one or more additional surfaces that can be densified in the same manner in a simultaneous operation.
Patent BR-0318266-A (BR)
Title: Processo de fabricação e produto resultante para aglomerado flexìvel de madeira
Inventor: RAMOS JOSE FLAVIO FROHLICH
IPC: B27N3/04
Filed: 2003-03-14
Abstract: "PROCESSO DE FABRICAçãO E PRODUTO RESULTANTE PARA AGLOMERADO FLEXìVEL DE MADEIRA". Constituindo-se num produto similar a tecido, sendo composto de resinas, fibras e cascas de madeira de reflorestamento, sendo dotado de flexibilidade e resistência, admitindo a sua aplicação no ramo do vestuário, na confecção de bolsas, sacolas, capas de agenda, para o artesanato e como revestimento no setor moveleiro.
Patent BR-8107673-A (BR)
Inventor: HOLTZMAN BARRY L
IPC: H01G4/38
Filed: 1981-11-25
Abstract: A power capacitor and method of making it employs the technique of stacking capacitor sections together in an enclosure of which each section includes rolled electrode foils and dielectric layers of which at least one of the electrodes has a rolled edge resulting in a greater thickness in that portion of the section. In order to permit thorough impregnation of the section, the winding tension is deliberately made loose and the initially resulting section is insufficiently tight to retain conductive tabs reliably in contact with the foil electrodes. The stacked sections have, however, between them in the body portion intermediate the rolled edges, one or more sheets of material that compress the body portion and insure reliable pressure contact thereat while not interfering with the impregnation of the fluid throughout the section.
Patent BR-8207661-A (BR)
Inventor: GUSTHIOT ANDRE
IPC: C08G18/18
Filed: 1982-04-23
Abstract: High resilience foams are produced by the reaction of a polyol containing primary hydroxy groups and an isocyanate containing a substantial proportion of toluene diisocyanate isomers using as sole effective catalyst, a quaternary ammonium carboxylate derivative of a tertiary amine, which tertiary amine contains no reactive hydroxy groups.
Patent BR-8302049-A (BR)
Inventor: KARPISEK LADISLAV STEPHAN
IPC: B65B53/02
Filed: 1983-04-20
Abstract: Stretch wrapping apparatus comprising a puckering device 1 and an expandible rectangular frame 3 demountably supported on the puckering device. Belts 5 on the puckering device are provided to feed a length of plastic film tube 8 onto pillars 48 on the expandible frame to form a puckered band as a sub-base 11 supporting the belts is raised relative to the pillars. A drive housed in the puckering device disengagably connected to jacking means 52, 54, 55 on the puckering frame is provided to expand the frame and stretch the band to a size such that the expanded frame and the puckered band thereon can pass freely over the article to be wrapped.
Patent BR-8800162-A (BR)
Inventor: PIPKO GRIGORI
IPC: C05G3/00
Filed: 1988-01-19
Abstract: A method for the manufacture of physically prepared slow- release fertilizer by coating fertilizer particles with at least one layer of a substantially water insoluble metal salt formed in-situ from an organic acid having between 6 to 30 carbon atoms and a metal oxide or carbonate. Optionally, the coating layer contains micronutrients and inert materials. In a preferred embodiment, an additional layer of paraffin is added on the coating of metal salt of organic acid. The method is applicable for most of the known fertilizers. The method enables to vary the rate of fertilizer release and the release period time according to specific requirements.
Patent BR-8802226-A (BR)
Inventor: BRAVO GENESIO
IPC: A23G9/22
Filed: 1988-05-06
Abstract: A blade mixer device for liquid and/or doughy products contained in a cylindrical tank comprises a structure that supports at least a first and a second pair of blades (16,17) acting, respectively, on the base and on the wall of the said tank (11); the bearing structure can moreover be associated in a removable manner with an operating shaft which extends coaxially with the tank. Characteristically, the said structure consists of a portal element (15) restrained in a removable manner astride the top of the said operating shaft (22), to rotate together with it.
Patent BR-8806180-A (BR)
Inventor: BRAND REINHOLD
IPC: C01G23/07
Filed: 1988-11-24
Abstract: A catalyst for the selective reduction with ammonia of nitrogen oxides from an intimate mixture of at least 3 metals in the form of their oxides, namely, titanium, tungsten and at least one of the metals vanadium, iron, niobium, molybdenum, with an atomic ratio of Ti to the other metals of 1:0.001 to 1, wherein there is used as oxide of the titanium a product obtained by flame hydrolysis, which product is impregnated with solutions of the salts of the other metals and is dried and calcined at a high temperature.
Patent BR-8901812-A (BR)
Inventor: YAMADA TOYOKAZU
IPC: B65D77/20
Filed: 1989-04-18
Abstract: A multilayer structure comprising (C) a substrate layer, (A) a surface layer of a thermoplastic resin, and (B) an intermediate layer of a thermoplastic resin sandwiched between the (C) substrate layer and the (A) surface layer, wherein the (B) intermediate layer contains 0 to 70 % by weight of a flake inorganic filler, the peeling strength between the (A) surface layer and the (B) intermediate layer is from 0.3 to 2.0 kg/15mm, and the peeling strength between the (B) intermediate layer and the (C) substrate layer is at least 1.2 times as large as the peeling strength between the (A) surface layer and the (B) intermediate layer. When a packaging container is produced by forming the multilayer structure into a container body and sealing the container body with a lid, easy openability and high sealing property will be ensured because the opening of the packaging container is not operated by using the delamination between the sealed portion but by using the easy delamination between the surface layer (A) and the intermediate layer (B). The use of the multilayer structure for production of packages is economically advantageous because the recovered scrap can be reused as the material for the substrate layer (C) without affecting the peelability of the surface layer (A).
Patent BR-9000834-A (BR)
Inventor: SHERBA SAMUEL EUGENE
IPC: A01N43/80
Filed: 1990-02-21
Abstract: Disclosed herein is a composition useful for controlling algae comprising (A) a compound of the formula <CHEM> wherein X<1> ,X<2> are independently selected from hydrogen, halogen, trihalomethyl, cyano, and (C1 to C4) alkyl; Z is selected from the group consisting of hydrogen, halogen, cyano, carboxy or salt thereof, alkylthio, carbalkoxy, carboxyalkyl, carbalkoxyalkyl, carbalkoxyalkooxycarbonyl, carbalkoxyalkoxy, alkoxy, cycloalkoxy, alkenyl, alkyl, cycloalkyl, unsubstituted or substituted amino, R<2>O in which R<2> represents a hydrogen atom or the esterbonded acid radical of an inorganic or organic oxyacid and acyloxy;  p is an integer from 1 to 2n+1;  m is an integer of 0 to 2n;  n is an integer of 1 to 5;  m+p = 2n+1 and (B) a 3-isothiazolone. o
Patent BR-9003233-A (BR)
Inventor: BRENNAN KARL WILLIAM
IPC: A61B17/06
Filed: 1990-07-06
Abstract: A braided surgical suture (30) is provided which in a first embodiment is woven in a spiral braid. The suture (30) is braided by moving thread carriers from position to position around a circular path. As each carrier moves it moves from its present position to a succeeding position which is at least two positions removed from its present position. Such spiral braided sutures (30) are advantageously produced without core filaments, providing benefits in strength, smoothness, pliability and cylindrical uniformity without the discontinuity of properties characteristic of conventionally braided cored sutures. In a second embodiment the suture is woven in a lattice braid, providing a plurality of distributed core passageways for individual core fibers.
Patent BR-9007602-A (BR)
Inventor: SVENSSON KJELL
IPC: G07B5/02
Filed: 1990-08-16
Abstract: A continuous, flexible ticket strip for use with a ticket dispenser (10) is disclosed, which ticket strip is provided at regular intervals with pairs of cuts (44a,44b), and which cuts define generally tongue-shaped flaps (45) and flap openings (46). The tickets are joined by shoulders (48,49) and bridges (50), the bridges (50) preventing the flaps (46) protruding from the plane of the ticket strip and becoming caught in the ticket dispenser (10). <IMAGE>
Patent BR-9100284-A (BR)
Inventor: SOVAK MILOS
IPC: B23D61/18
Filed: 1991-01-23
Abstract: The invention concerns a cutter link (31) for a saw chain, comprising a base member (36) having holes (34, 35) therethrough for connecting links together by means of pintles (13); a raker (42) formed at the forward end of said base member (36) above said holes (34, 35) and having a rearwardly facing end (44); and a body (37) formed rearwardly of said raker (42) and spaced therefrom, the forward end (41) of said body (37) having a cutting edge which is generally round and facing the rearwardly facing end (44) of said raker (42), said cutting edge being of generally the same shape as said rearward facing end (44) of said raker (42). <IMAGE>
Patent BR-9101422-A (BR)
Inventor: MADRZAK ZYGMUNT
IPC: B65H19/10
Filed: 1991-04-03
Abstract: For the purpose of producing a web splice an adhesive tape is used which has an adhesive layer (3) essentially only on one side. The cover film of this adhesive layer consists of two parts (4 and 5) which are separated by a longitudinal seam (9). Applied on the other side of the substrate (band 2) of the adhesive layer (3) is at least one narrow adhesive strip (7), also having a cover film (8), which is preferably situated at one edge of the adhesive tape (1). 
<IMAGE>
Patent BR-9103768-A (BR)
Inventor: DAVIS ROBERT BERNARD
IPC: D04H1/46
Filed: 1991-08-30
Abstract: The present invention relates to a fabric for a paper making machine which fabric comprises a woven substrate carrying batt fibre on the surface thereof characterised in that at least one of the batt fibre and the substrate comprises a polyetherketone.
Patent BR-9204160-A (BR)
Inventor: RIENECKER REIMUND
IPC: D21D5/02
Filed: 1992-10-19
Abstract: The invention relates to a screening apparatus which has at least one each of a housing attachment part (1, 1') and housing main part (2, 2') which each have a hollow-cylindrical (8, 8', 9, 9') and/or frustoconical housing outer wall with at least two coaxial, essentially rotationally symmetrical screening baskets (3, 3', 4, 4') with a rotor (5, 5') having pulsation elements (7), the accepted material chamber (37) being arranged radially outside the screening baskets (3, 4) and the rotor part (rotor parts) with the pulsation elements (7) radially inside the screening baskets (3, 4), the inflow (19) into the housing being arranged centrally in the region between the screening baskets (3, 4) and the outflow channel (26) for accepted material being arranged also in the region between the two screening baskets (3, 4). The invention is characterised in that, at least in the region of the screening baskets (3, 3', 4, 4'), only one housing main part (2, 2') and housing attachment part or housing mount part (1, 1') in each case is provided and in that the first screening basket (3, 3') is fastened in the housing attachment part or housing mount part (1, 1') and the second screening basket (4, 4') is fastened in the housing main part (2, 2'). <IMAGE>
Patent BR-9205049-A (BR)
Inventor: PORTER CLYDE R
IPC: A47C3/30
Filed: 1992-12-17
Abstract: A hydraulic positioner 10 comprises a cylinder 12, a piston chamber 32 in said cylinder closed at one end by an axially displaceable gland 24, a piston 30 axially reciprocable in said first chamber, a rod 16 axially connected to said piston and slidable through said gland, said rod moveable with said piston between an extended and a compressed condition, hydraulic fluid in said piston chamber, valve means 40 in said piston actuatable for allowing flow of said fluid across said piston, said valve means being normally closed for locking said piston and said rod against movement in said cylinder, first spring means 18 urging said rod to said extended condition, and second spring means 74 urging said gland against said fluid to compensate for changes in fluid volume in said chamber. <IMAGE>
Patent BR-9205677-A (BR)
Inventor: HOLMGREM JAN
IPC: A61K39/02
Filed: 1992-02-25
Abstract: Disclosed is a method of producing a vaccine composition against enteric infection caused by enterotoxigenic E. coli bacteria in humans. E. coli strains selected from different known strains each having the ability of expressing a certain type of colonization factor antigens are grown in a liquid culture medium. Finally formalin-killed E. coli strain having substantially preserved antigenic and hemagglutinating properties of said certain type of colonization factor antigens, is mixed with a pharmaceutically acceptable excipient and/or diluent. Further disclosed is a method of preventing an enteric infection caused by enterotoxigenic E. coli bacteria in humans, whereby a vaccine composition comprising inactivated E. coli strain is administered to a human being for the prevention of said infection.
Patent BR-9206836-A (BR)
Inventor: BREIVIK KARE
IPC: B67D/
Filed: 1992-03-30
Abstract: PCT No. PCT/NO92/00058 Sec. 371 Date Aug. 8, 1994 Sec. 102(e) Date Aug. 8, 1994 PCT Filed Mar. 30, 1992 PCT Pub. No. WO93/11035 PCT Pub. Date Jun. 10, 1993.A buoy for use in loading or unloading a flowable medium, especially oil from a vessel at sea. The buoy includes an outer member and a central member rotatably mounted in the outer member. The central member forms a passage for the flowable medium from the lower end of the buoy which is connected to a transfer line to a tube system within the vessel. The outer member is received and latched in an opening in the bottom of the vessel. The central member is connected to the tube system by a swivel means coupled to the upper end of the central member by a flexible joint which allows angular displacement about the axis of connection.