baber/WOPTO huggingface dataset:
Patent DK-0738148-T3 (DK)
Inventor: NICOLAOU K C
IPC: C07D411/14
Filed: 1995-01-11
Granted: 2002-11-04
Abstract: Onium salts of taxo-diterpenoid-Cn,2-O-aza-arenes form water soluble self-assembling nanostructures above a critical aggregation concentration. The onium salt of aza-arene includes a delocalized charge which renders derivatized taxo-diterpenoids amphoteric, enhances their solubility in water, and promotes self-assembly of water soluble nanostructures, e.g., helical fibular structures and spherical micellular structures. These same onium salts of taxo-diterpenoid-Cn,2-O-aza-arenes are employed as water soluble prodrugs. For example, taxol-2'-methylpyridinium tosylate (MPT) is characterized by an elevated aqueous solubility, rapid activation by serum protein, good stability in most other aqueous solutions, formation of a protein:taxol intermediate and good retention within the circulatory system. The toxicity of the activated form is comparable or greater than underivatized taxol. Furthermore, taxol-2'-MPT can be synthesized by a simple one step reaction between taxol and 2-fluoro-1-MPT. The invention is applicable to taxol and taxol memetics having hydroxyls that are reactive with onium salts of 2-halogenated-aza-arenes. For example, taxol, C-2 substituted taxol and Taxotere each have reactive hydroxyls at the 2' and 7 positions. The invention is also applicable to a wide array of 2-halogenated-aza-arenes.
Patent DK-0769932-T3 (DK)
Inventor: BRAUKER JAMES H
IPC: A61K35/12
Filed: 1995-06-29
Granted: 1999-06-23
Abstract: An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.
Patent DK-0756092-T3 (DK)
Inventor: LEIBLE DIETER
IPC: F16B13/14
Filed: 1996-06-12
Granted: 1999-06-14
Abstract: The plug's (10) shaft is positioned in a sleeve-shaped (16) anchoring piece running backwards from the foot (20) of the plug. The periphery of the sleeve has wedge-shaped teeth (22) forming elastically resilient expansion elements at least over part of the shaft. The teeth have one flat flank pointing towards the foot of the plug, and a steep flank pointing to the head (14). The teeth are arranged in several peripherally adjacent axially positioned rows spaced apart from each other.
Patent DK-0804888-T3 (DK)
Inventor: SCHNEIDER JEAN-MARC
IPC: A47C1/022
Filed: 1996-04-22
Granted: 1998-07-27
Abstract: The seat has an adjuster for regulating various moveable and deformable elements which are grouped together in a multi-function device and provide a way of altering the chair users position. The way for altering one or more of the elements is via an external command point (5,8). A first command is carried out by rotation of a first axle at the command point, a second by a second coaxial axis and a third by movement of the second axis along the first axis. Raising of the seat is by use of a pneumatic system with a compressed gas cylinder, tilting by a system with a coiled spring which is tensioned accordingly, the multi-position feature is more accurate use of the separate position features.
Patent DK-0811073-T3 (DK)
Inventor: WILSON JAMES M
IPC: A61K38/20
Filed: 1996-02-23
Granted: 2007-05-21
Abstract: A method of reducing immune response during gene therapy is provided which involves co-administration of the viral vector bearing a therapeutic transgene and a selected immune modulator capable of inhibiting the formation of neutralizing antibodies and/or CTL elimination of the vectors upon repeated administration.
Patent DK-0824574-T3 (DK)
Inventor: PRIBSTER MANFRED
IPC: C09K3/10
Filed: 1996-05-07
Granted: 2000-04-17
Abstract: PCT No. PCT/EP96/01899 Sec. 371 Date Mar. 24, 1998 Sec. 102(e) Date Mar. 24, 1998 PCT Filed May 7, 1996 PCT Pub. No. WO96/35761 PCT Pub. Date Nov. 14, 1996Two component adhesive/sealing masses based on silane terminated prepolymers contain a component A which is a one-component, humidity hardening adhesive/sealing mass with high initial adhesiveness, and a component B which is a crosslinking agent and/or accelerator for component A are disclosed. These adhesive/sealing masses are suitable for gluing without primer parts made of metals or other materials such as aluminum, steel, glass, wood or plastics. In a particularly preferred embodiment, component B consists of a viscous, stable mixture of plasticisers, water, thickeners and other optional auxiliary substances.
Patent DK-1006828-T3 (DK)
Inventor: MINKKINEN HANNU
IPC: A43B7/02
Filed: 1996-07-04
Granted: 2003-12-08
Abstract: A footwear sole construction has an insulating layer (1) with poor heat conductivity but good permeability to heat radiation, the insulating layer (1) and a reflective layer (4) attached thereto being placed between the inner lining or the like and the wear sole. The reflective surface (4a) of the reflective layer is attached directly to the material of the insulating layer (1), e.g. by attaching a metal foil to the insulating layer (1) by vacuum evaporation.
Patent DK-0847441-T3 (DK)
Inventor: FULLER JESS PAUL
IPC: C12M3/04
Filed: 1996-08-23
Granted: 2001-08-06
Abstract: PCT No. PCT/GB96/02070 Sec. 371 Date Feb. 27, 1998 Sec. 102(e) Date Feb. 27, 1998 PCT Filed Aug. 23, 1996 PCT Pub. No. WO97/08291 PCT Pub. Date Mar. 6, 1997A roller bottle and method of culturing biological material, such as cells, using the roller bottle are disclosed. The roller bottle comprises a rough or uneven polymeric inner cell growth surface for culturing the cells. The growth surface is formed as an integral part of the roller bottle. The rough or uneven growth surface is provided by the inner growth surface being pitted or cratered to a depth of 1 mm or less. Further, the craters of the inner growth surface may be in the form of micro-cupels and measure less than 2 mm across.
Patent DK-0853591-T3 (DK)
Inventor: EDUARD JOZEF MARIE DUIJNSTEE
IPC: B66B9/08
Filed: 1996-10-02
Granted: 2000-10-23
Abstract: PCT No. PCT/NL96/00382 Sec. 371 Date Jul. 2, 1998 Sec. 102(e) Date Jul. 2, 1998 PCT Filed Oct. 2, 1996 PCT Pub. No. WO97/12830 PCT Pub. Date Apr. 10, 1997A running gear (3), for a drive mechanism of a rail-guided displacement device, such as a passenger lift, comprising a base part, a drive and at least two sets of guide wheels (9), arranged behind each other, viewed in direction of travel of the running gear, so that, during use, the running gear is guided along the rail in a desired position by the guide wheels, the base part comprising at least a bridge piece (5), a first and a second frame part (6, 7), the frame parts each being connected to the bridge piece so as to be movable about at least one pivotal axis, each frame part carrying a set of guide wheels and the frame parts being mutually coupled by coupling means which form a mechanical mirror, so that the movements of the first and the second part are always each other's mirror image in a first plane of symmetry extending at right angles to the driving direction of the running gear between the first and the second frame part, and viewed relative to the bridge piece.
Patent DK-0859905-T3 (DK)
Inventor: WOODHOUSE TIMOTHY CHARLES
IPC: F16N7/24
Filed: 1996-11-06
Granted: 2000-09-04
Abstract: PCT No. PCT/GB96/02713 Sec. 371 Date Jul. 7, 1998 Sec. 102(e) Date Jul. 7, 1998 PCT Filed Nov. 6, 1996 PCT Pub. No. WO97/17530 PCT Pub. Date Mar. 15, 1997The invention provides, in one aspect, a lubrication system for internal combustion engines of the kind comprising a crankshaft (1) and an associated oil sump (3), a camshaft in a cylinder head above the oil sump, and a timing belt (5) connecting the crankshaft and camshaft via respective, pulleys (2, 4). In accordance with the invention, the timing belt is adapted to entrain a sufficient quantity of oil from the oil sump to lift it to the cylinder head for lubricating purposes, thereby eliminating the need for a separate oil pump. Preferably, an oil pulley (7) is provided below the crankshaft pulley (2) positioned to be immersed in oil within the oil sump for entraining oil therefrom. In one form, in which the crankshaft and camshaft pulleys (2, 4) have similarly formed tooth sets of different diameters to effect the timing required, the timing belt (5) is of an impermeable material over its width and is formed with a set of teeth (6) around its inner face meshing with said toothed pulleys, the oil pulley also has a tooth set (8), and the timing belt has an additional set of teeth (9) extending around its outer face for meshing with the teeth of the oil pulley, said outer teeth providing the means for entraining oil to the cylinder head. In another aspect of the invention, an engine lubrication system is provided wherein a toothed pulley (2 or 4), is provided, the teeth (32, 36) of which run over a part of their rotation in a restricted passage provided by a casing (10) and a belt (5) having mating teeth also runs for part of its movement in a restricted passage provided by said casing, these runs being guided to a meeting point (33, 35) at which oil under pressure is available as a result of meshing action of the two sets of teeth.
Patent DK-0802210-T3 (DK)
Inventor: YUVA NUSRET
IPC: C08G18/80
Filed: 1997-04-04
Granted: 2004-11-01
Abstract: Aqueous or water-dilutable blocked polyisocyanates (I) derived from (a) 40-80 wt% polyisocyanate component based on di- isocyanates with mol. wts. of 140-350 and an isocyanurate group content of 2-30 wt%, (b) 5-30 wt% monofunctional blocking agent(s) for isocyanate groups, (c) 0.5-15 wt% mono- or di- functional stabiliser(s) with a mol. wt. of 70-300 containing 1-2 hydrazide groups, (d) 5-30 wt% non-ionic hydrophilic component consisting of mono- or di-functional compound(s) with at least one polyether chain, (e) 0-15 wt% (potentially) anionic component comprising component(s) with at least one group which reacts with isocyanate groups and at least one salt-forming group which may be at least partly neutralised, (f) 0-15 wt% (cyclo)aliphatic polyamine(s) with 2-3 amino groups and a mol. wt. of 60-300, and (g) 0-15 wt% polyhydric alcohol(s) with 2-4 hydroxyl groups and a mol. wt. of 62-250, in which the contents of (h) isocyanurate, (i) blocked isocyanate and (k) chemically-linked hydrazide groups are at least 2 wt%, 5-11 wt% and 0.1-3.0 wt% respectively. Also claimed is a process for the production of (I).
Patent DK-0883693-T3 (DK)
Inventor: CLARKSON JOHN MICHAEL
IPC: C12Q1/6825
Filed: 1997-02-18
Granted: 2000-11-06
Abstract: A method estimating a property or parameter of a nucleic acid material, which property or parameter is one to which the electrical conductivity of the nucleic acid material is related, comprises measuring the electrical conductivity of the nucleic acid material, and estimating from the measurement the property or parameter of the material by reference to a predetermined relationship between electrical conductivity and said property or parameter. This is based on the discovery that there are certain important properties of nucleic acids, the quantitative determination of which is frequently desirable, which can be assessed by measurement of the conductivity of a solution of the nucleic acid or acids. Changes in such properties may be reflected in corresponding changes of electrical conductivity. The concentration of nucleic acid in solution and the molecular weight of a species of nucleic acid are examples of important property which may be determined.
Patent DK-0929589-T3 (DK)
Inventor: PUDLEINER HEINZ
IPC: C08G18/82
Filed: 1997-09-18
Granted: 2001-06-05
Abstract: The invention concerns a method of improving the biocompatibility of thermoplastic polyurethanes by extracting toxic constituents with an organic solvent. The invention further concerns the use of the resultant cell- and tissue-compatible materials for producing medical articles.
Patent DK-0972218-T3 (DK)
Inventor: ROLLER THOMAS W
IPC: G02B6/38
Filed: 1998-03-31
Granted: 2002-05-27
Abstract: The proximal connector includes a stainless steel cone-shaped ferrule enclosing a proximal end of the optic fiber element. The ferrule is inserted within a matching aperture of a receiving block which is also made of stainless steel. The matching shapes of the ferrule and the aperture of the receiving block ensure effective heat transference from the ferrule into the receiving block. Both ferrule and the aperture are axially symmetric such that any rotation of the proximal connector while inserted into the receiving block does not change the location of the entrance aperture of the optic fiber element. The proximal connector also includes a case having an indented ring. A ball plunger biasing mechanism is mounted within the aperture of the receiving block and is positioned for engaging with the indented ring only while the proximal connector is fully and securely inserted within the aperture. The plunger prevents accidental removal of the proximal connector while also providing a biasing force for ensuring solid contact between the cone-shaped ferule and the corresponding portions of the receiving block to further facilitate the heat conduction.
Patent DK-0980253-T3 (DK)
Inventor: CAWTHORNE MICHAEL ANTHONY
IPC: A61K38/08
Filed: 1998-05-13
Granted: 2004-07-05
Abstract: The present invention relates to a method of treating insulin resistance or Syndrome X. The method includes the step of administering a therapeutically effective amount of a somatostatin or a somatostatin agonist to said patient. The invention also includes pharmaceutical compositions comprising a somatostatin or somatostatin agonist and the use of such products in the preparation of such compositions.
Patent DK-0977856-T3 (DK)
Inventor: TRIEBEL FREDERIC
IPC: C07K14/725
Filed: 1998-06-03
Granted: 2004-12-20
Abstract: This invention concerns an isolated nucleotidic sequence selected from the group consisting of :   a) the nucleotidic sequences SEQ ID N DEG  1, SEQ ID N DEG 3 or SEQ ID N DEG 5 ; b) the nucleotidic sequences which hybridize under stringent conditions to any of the sequences defined in a) and which code for a polypeptide which is a variant of the LAG-3 molecule ; c) the nucleotidic sequences which are degenerated as results of the genetic code to the nucleotidic sequences defined in a) and b), and which code for a polypeptide which is a genetic variant of the LAG-3 molecule.
Patent DK-0992449-T3 (DK)
Inventor: FOLLI STEFANO EL
IPC: B66B3/00
Filed: 1999-09-04
Granted: 2003-03-17
Abstract: Lift shaft information is produced from a shaft information detector (4) arranged on the lift cables (9), and from a sensor unit arranged in the lift cage (1). At least one carrier is displaceably arranged on the cables for carrying the shaft information detector. The carrier may have a strut with guide slots and/or clamping slots for receiving the cable. The shaft information detector is a magnet which produces information by changing the switching state of a magnetic switch of the sensor unit.
Patent DK-0992415-T3 (DK)
Inventor: BONDON FABIENNE
IPC: B61F5/24
Filed: 1999-10-04
Granted: 2004-04-26
Abstract: The system consists of a housing (4) resting on supports (6, 8) such as bogies and containing first and second symmetrical power cylinders (10, 10') between the supports and the housing. The power cylinders have first (24, 24') and second (26, 26') hydraulic fluid-filled chambers which compress and expand with variations in the distance between the housing and supports. The chambers are linked by hydraulic lines (28, 28') with valves to pressurised gas accumulators (32, 32').
Patent DK-1051502-T3 (DK)
Inventor: BROWN WILLIAM C
IPC: C12N15/09
Filed: 1999-01-27
Granted: 2007-02-26
Abstract: The invention relates generally to recombinant methods and materials for effecting the microbial production of useful polypeptides. More particularly, the invention relates to expression vector systems which utilize a translational repressor system, and transcriptional control proteins to provide a highly efficient, tightly regulated, staged inducible promoter system capable of expressing exogenous genes, including toxic genes, in E. coli.
Patent DK-1083945-T3 (DK)
Inventor: LI REBECCA
IPC: A61K9/00
Filed: 1999-04-13
Granted: 2002-10-21
Abstract: A device is prepared having cells or tissue attached to a non-degradable filamentous matrix surrounded by a semi-permeable membrane. The matrix is preferably formed of a plurality of monofilaments twisted into a yarn or woven into a mesh, and can be in the form of a cylinder. When implanting the device, the semi-permeable membrane is preferably immunolsolatory, and the cells or tissue may produce a biologically active molecule to provide therapy. To enhance cell or tissue adhesion, the matrix is coated with extracellular matrix molecules or treated to provide a surface charge. The device can be made by inserting the matrix into a capsule formed of the semi-permeable membrane, distributing the cells or tissue on the matrix through an opening of the capsule, and sealing the opening of the capsule.
Patent DK-1123386-T3 (DK)
Inventor: MATTES RALF
IPC: C12P41/00
Filed: 1999-10-13
Granted: 2007-05-07
Abstract: The invention relates to nucleic acid sequences which code for a polypeptide having nitrilase activity, to nucleic acid constructs comprising the nucleic acid sequences, and to vectors comprising the nucleic acid sequences or the nucleic acid constructs. The invention further relates to amino acid sequences which are encoded by the nucleic acid sequences, and to microorganisms comprising the nucleic acid sequences, the nucleic acid constructs or vectors comprising the nucleic acid sequences or the nucleic acid constructs.The invention additionally relates to a process for preparing chiral carboxylic acids from the racemic nitriles.
Patent ES-2228306-T3 (ES)
Inventor: LORCH WERNER
IPC: G05D23/13
Filed: 2000-01-13
Granted: 2005-04-16
Abstract: The mixing armature comprises an inlet for cold water and one for warm water. A control system (2) is connected to the inlet and outlet of water by the thermostat valve (16). The control system is set up s that on the beginning of the opening movement of the valve, a direct connection is formed between the inlet of cold water and the mixed water outlet. The control system has control discs (4,5).
Patent ES-2451615-T3 (ES)
Title: Mejoras relativas a un sistema de televisión
Inventor: ENTWISTLE PAUL
IPC: H04N5/445
Filed: 2000-07-07
Granted: 2014-03-28
Abstract: Un sistema de televisión para visualizar un programa seleccionado de una pluralidad de programas (10; 12; 14;16) disponibles para ser vistos por un usuario del sistema, comprendiendo el citado sistema un receptor de datos deemisión para recibir video, audio y datos auxiliares emitidos y generar video en una pantalla a partir de los datos, unmedio para la selección por parte del usuario de programas para ser vistos, siendo los citados programas mostradosen una pantalla de Guía de programas Electrónica (EPG - Electronic Programme Guide, en inglés) en pantalla y quemuestra al usuario un número de programas disponibles para ser seleccionados para ser vistos en un período detiempo indicado, una base de datos en la cual se almacena información relativa a aquellos programas que han sidopreviamente seleccionados para ver por el usuario en un período de tiempo designado precedente, junto con unaindicación del período de tiempo para el cual fueron vistos los programas y, si algún programa (10; 12; 14; 16)subsiguientemente seleccionado para ver por el usuario y/o que es subsiguientemente mostrado en la pantalla deEPG en la pantalla como disponible para ser seleccionado para ver, ya está identificado en la base de datos, esteprograma es indicado (17; 19) al usuario mediante una visualización de pantalla como ya visto y la citadavisualización de pantalla incluye una indicación de la porción del programa que ha sido vista previamente.
Patent ES-2212979-T3 (ES)
Inventor: LINDQUIST TOMMY
IPC: A47L13/40
Filed: 2000-11-06
Granted: 2004-08-16
Abstract: A device for a vacuum cleaner that has a vacuum source (12) connected to an inlet channel, and an outlet channel for air flowing through the vacuum cleaner. The vacuum cleaner includes a device for electrostatically charging a feather-duster (20) or a micro fiber type with static electricity. <IMAGE>
Patent ES-2223445-T3 (ES)
Inventor: ROTH HEINZ
IPC: B65G57/18
Filed: 2000-01-27
Granted: 2005-03-01
Abstract: The cut product pieces(25) of each stacked layer(30) banked up by the cross conveyors are collected and transported in finished layers directly after the cross conveying and during their transportation. The zig-zag fashion alignment of the cut product pieces takes place during their further transportation to the delivery device.  An Independent claim is included for a plant for the formation of boxed stacks which has a device for cross movement of every other cut product piece by a predetermined length, and a device to prevent cross movement of the cut product parts lying in-between along the first stack edge.
Patent ES-2215634-T3 (ES)
Title: Procedimiento de sincronizacion del encendido.
Inventor: NEHSE WOLFGANG
IPC: F02D41/34
Filed: 2000-04-13
Granted: 2004-10-16
Abstract: Procedimiento de sincronización del encendido en un motor de combustión interna con un emisor de cigüeñal y un dispositivo de reconocimiento de la estabilidad de marcha, caracterizado por los pasos de que después de la puesta en marcha de vehículo se efectúa al menos en un cilindro un encendido en todos los puntos muertos superiores (OTs), realizándose en OTs determinados un desplazamiento en el instante de encendido en un valor determinado, mediante el reconocimiento de la estabilidad de marcha se capta la repercusión del desplazamiento del instante de encendido y se supone un OT de encendido en el punto muerto superior en el que se efectúa el desplazamiento del instante de encendido cuando se modifica la estabilidad de marcha por encima de un valor límite prefijado, y se supone un OT de encendido en el punto muerto superior en el que no se efectúa desplazamiento alguno del instante de encendido cuando la estabilidad de marcha no varía por encima de un valor límite prefijado.
Patent ES-2209886-T3 (ES)
Title: Engranaje de conmutacion.
Inventor: SCHUMANN PETER
IPC: B60N2/90
Filed: 2000-03-23
Granted: 2004-07-01
Abstract: Engranaje de conmutación para al menos dos dispositivos de ajuste en automóviles para transmitir la fuerza de accionamiento de un accionamiento (3a) manual o a motor por medio de al menos un elemento (2a a 2e) de acoplamiento a, como mínimo, un elemento (1a a 1e) de accionamiento de cada dispositivo de ajuste, estando dispuesto este elemento de accionamiento concéntrico a al menos un elemento del engranaje del accionamiento (3a), con lo que los elementos (1a a 1e) de accionamiento individuales pueden acoplarse, a elección, con el accionamiento (3a) por medio de el al menos un elemento (2a a 2e) de acoplamiento, y con lo que está previsto al menos un conmutador (4a a 4g; 5a a 5d; 40e a 40g) para bloquear o liberar el elemento (2a a 2e) de acoplamiento, especialmente para ajustar los asientos del automóvil, caracterizado porque el, como mínimo, un elemento (2a a 2e) de acoplamiento puede ensamblarse, mediante el giro, con un elemento de accionamiento que se va a accionar en cada caso, y porque el como mínimo un elemento (2a a 2e) de acoplamiento puede bloquearse con el conmutador (4a a 4g; 5a a 5d; 40e a 40g) de tal manera que se impide que se acople con un elemento (1a a 1e) de accionamiento que no se va a accionar.