baber/WOPTO huggingface dataset:
Patent HR-P20170857-T1 (HR)
Title: Styrylpyridine derivatives and their use for binding and imaging amyloid plaques
Inventor: KUNG HANK F
IPC: C07D213/16
Filed: 2017-06-06
Abstract: This invention relates to a method of imaging amyloid deposits and to styrylpyridine compounds, and methods of making radiolabeled styrylpyridine compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits.
Patent SI-1618046-T1 (SI)
Title: Blister pack
Inventor: PASBRIG ERWIN
IPC: B65D75/00
Filed: 2004-04-05
Abstract: A tropical blister pack (10) having a heat-shaped plastic blister base section (12) and a covering foil (16) over the blisters (14) and against the package edge (20), sealed against the reverse side of the blister base, is new. The base is covered by a further foil (18) as a sealing trough. A tropical blister pack (10) having a heat-shaped plastics blister base section (12) and a covering foil (16) over the blisters (14) and against the package edge (20), sealed against the reverse side of the blister base, is new. The base is covered by a further foil (18) as a sealing trough. Between the under foil and the blister base there is a peelable varnish as a hot seal applied at a rate of 2-20 g/m 2> and preferably 7-15 g/m 2>, or a peelable plastics film with a thickness of 10-40 Microm and preferably 15-30 Microm, or a peelable plastics coating at a rate of 5-40 g/m 2> and preferably 7-20 g/m 2>. When the lower shrouding has been peeled away, the blister contents can be seen. The plastics material of the blister base incorporates a barrier against the entry of water vapor or gas.
Patent SI-1466600-T1 (SI)
Title: Ready-to-use oxaliplatin solutions
Inventor: SCHRIDDE EDGAR
IPC: A61K9/08
Filed: 2004-03-26
Abstract: Pharmaceutical composition comprises water, oxaliplatin and an acid, other than oxalic acid, whose anion does not impair the stability of the solution. An independent claim is also included for a pharmaceutical composition comprising water, oxaliplatin and more than 5 wt.% glucose. ACTIVITY : Cytostatic. MECHANISM OF ACTION : None given.
Patent SI-2141691-T1 (SI)
Title: Adaptable noise creation device
Inventor: BORGMANN UDO
IPC: G10K11/00
Filed: 2008-07-03
Abstract: The device (1) has an actuator (3) arranged on a carrier plate (2) that is excited by vibrations. The plate is connected with an acoustic insulating material (9). Noise signals of the actuator are regulated by a control/regulation device (4) that is connected with the actuator. An amplifier (5) is arranged between the device (1) and the actuator. The plate is formed as a wall plate, ceiling plate, floor plate, room divider, furniture plate, cabinet plate and/or partition wall. A memory of a computer of the device (4) stores noise tone-characteristics that are changeable by a preset program. The insulating material is selected from mineral wool, gypsum foam, aluminum foam, polyurethane foam, melamine resin foam, hemp wool, non-woven fabric and/or felt material.
Patent SI-2440239-T1 (SI)
Title: Hemoglobin compositions
Inventor: ABUCHOWSKI ABRAHAM
IPC: A61K38/00
Filed: 2010-06-09
Abstract: The invention provides compositions containing hemoglobin, particularly PEGylated hemoglobin. The PEGylated hemoglobin molecule is capable of transferring oxygen or carbon monoxide bound thereto to a tissue with which it is in proximity. Exemplary PEGylated hemoglobin formulations of the invention are virally inactivated. Various compositions of the invention include deoxygenated hemoglobin, which may be conjugated with one or more water-soluble polymer. PEGylated hemoglobin includes those species in which the iron atom of the hemoglobin molecule is not bound to oxygen or any other species, and hemoglobin molecules in which a species other than oxygen, e.g., carbon monoxide, is bound to the iron atom. The compositions of the invention are formulated as hypo-, iso- or hypertonic solutions of the PEGylated hemoglobin. The compositions are of use to treat and/or ameliorate disease, injury and insult by providing for the oxygenation of tissues and/organs.
Patent SI-2916866-T1 (SI)
Title: Formulation for bispecific t-cell engagers (bites)
Inventor: OLBRICH CARSTEN
IPC: C07K16/00
Filed: 2013-11-05
Abstract: The present invention relates to stable pharmaceutical compositions which contain polypeptides having at least two antigen-binding domains and are especially suited for subcutaneous administration. The invention provides liquid compositions which minimize the formation of undesired polypeptide aggregates (dimers and/or multimers). The present invention further provides a method for minimizing the aggregation of polypeptides having antigen-binding domains in liquid compositions.
Patent TR-200700896-T1 (TR)
Inventor: COLGIN MARK A
IPC: G01N33/53
Filed: 2005-07-25
Abstract: An immunoassay test device is provided for detecting the presence of a molecule differentially associated with appendicitis in a sample from a patient suspected of having appendicitis. The device includes a first antibody specific to the molecule, a support for the first antibody, means for contacting the first antibody with the sample, and means for detecting binding of the first antibody with the molecule. MRP-8/14 and haptoglobin are examples of molecules differentially associated with appendicitis. In one embodiment, the device is in a flow-through format for testing blood samples.
Patent TR-200905039-T1 (TR)
Title: Bir ocak.
Inventor: UESTUENDAG ERTUGRUL
IPC: H05B3/74
Filed: 2007-12-28
Abstract: Bu buluş, şekli sayesinde, hem ısıtıcı taşıyıcıya (3) kuvvet uygulanarak üst tablaya (2) doğru bastıran ve ısıtıcı taşıyıcının (3) üst tabla (2) ile temasını artıran, hem de, ısıtıcı taşıyıcıyı (3) alt tablaya (4) sabitleyen bir yay (5) içeren bir ocak (1) ile ilgilidir.
Patent DE-3587313-T2 (DE)
Inventor: KITCHEN ALONZO GENE
IPC: C08L23/08
Filed: 1985-02-26
Granted: 1993-08-12
Abstract: Resinous polymodal block copolymers of such as butadiene and styrene which are craze-resistant, transparent, and substantially color-free, and methods of producing the block copolymers. The copolymers are prepared by sequential charge copolymerization modes comprising the solution polymerization of at least two charges each of a conjugated diene, a monovinylarene, and a monoalkali metal initiator, at least one charge of conjugated diene monomer precedes the last charge of monoalkali metal initiator, at least one charge each of monovinylarene and of conjugated diene follows the last charge of monoalkali metal initiator, and the final charge of monomer is a charge of conjugated diene monomer, such that the number of charges of each of said components is not more than three, and the total of the charges of the three components is 8 or 9.
Patent DE-3750137-T2 (DE)
Inventor: THORNCRAFT DAVID
IPC: G02B6/36
Filed: 1987-11-09
Granted: 1994-10-27
Abstract: PCT No. PCT/AU87/00380 Sec. 371 Date Sep. 12, 1988 Sec. 102(e) Date Sep. 12, 1988 PCT Filed Nov. 9, 1987 PCT Pub. No. WO88/03661 PCT Pub. Date May 19, 1988.A method of fabricating a fused fibre optic coupler includes disposing two or more segments of optical fibre under longitudinal tension. The tensioned fibre segments are preheated to a temperature sufficient to soften the segments and thereby substantially relieve their tension by inelastic stretching of the segments. After the segments have cooled, the fibre segments are re-tensioned and then heated while in intimate side-by-side contact to a temperature sufficient to cause the fibre segments to fuse together.
Patent DE-3752105-T2 (DE)
Inventor: STANLEY THOMAS RALPH
IPC: A22C11/02
Filed: 1987-12-15
Granted: 1998-01-08
Abstract: Apparatus and methods for stuffing food casing to produce sausage products with a high degree of dimensional uniformity for prepackaging applications. Substantially flat terminal end (14) portions for higher product yields are prepared by a stuffing sequence which includes a time delay from shut down of the meat pump to actuation of the end-closure device. The length of the delay in actuating the end-closure device is dependent on the time required for pressure in the stuffing horn to dissipate after shut-down of the meat pump. Substantially flat terminal ends may also be made by introdcing a time delay from actuation of the end-closure device to removal of the sizing ring from the end of the horn so that the length of the delay is also directly proportional to the viscosity of the meat emulsion.
Patent DE-3850818-T2 (DE)
Inventor: HOOVER DENNIS JAY
IPC: C07K5/065
Filed: 1988-06-24
Granted: 1994-11-17
Abstract: Renin inhibitors, useful as antihypertensives, of the formula:- <CHEM> or a pharmaceutically acceptable salt thereof, wherein X is O or NH; R1 is alkyl having one to six carbon atoms, imidazol-4-ylmethyl or methylthiomethyl; Y is <CHEM>  and R2 is CF2CONHCH3, CF3 or <CHEM> C
Patent DE-3881467-T2 (DE)
Inventor: MASAKI TOMOH
IPC: C12P21/02
Filed: 1988-09-23
Granted: 1993-10-21
Abstract: Disclosed is a vasoconstrictor peptide called Endothelin having a molecular weight of 2,500 +/- 300. Endothelin contains 21 amino acid residues, wherein four cysteines form two sets of S-S bond. In order to obtain the vasoconstrictor factors of the present invention, it is preferable to culture the endothelial cells collected from the vascular inner walls in a serum-free medium. The vasoconstrictor peptides of the present invention can be utilized as hypotension therapeutic agents or local vasoconstrictors to animals including humans.
Patent DE-3881703-T2 (DE)
Inventor: BRADY PETER
IPC: D06M14/06
Filed: 1988-08-18
Granted: 1993-10-07
Abstract: PCT No. PCT/AU88/00309 Sec. 371 Date Apr. 13, 1990 Sec. 102(e) Date Apr. 13, 1990 PCT Filed Aug. 18, 1988 PCT Pub. No. WO89/01541 PCT Pub. Date Feb. 23, 1989.A method of processing a textile material consisting wholly or partly of keratinous fibres, characterised in that the material is treated with an aqueous composition containing at least one compound which possesses one or more ethylenic double bonds activated by two adjacent carbonyl groups. Preferred compounds include fumaric acid or maleic acid, optionally substituted with one or two halo and/or alkyl groups; or a salt, ester or amide of any said acid; or an N-substituted maleimide, optionally substituted with one or two halo and/or alkyl groups.
Patent DE-3881862-T2 (DE)
Inventor: KUSAMA TSUNEO C O DAIICHI SEIY
IPC: C07H13/06
Filed: 1988-03-02
Granted: 1993-09-30
Abstract: Disaccharide compounds represented by formula (I): <CHEM> wherein R, R<1>, R<2>, R<3>, R<4>, and R<5> are as defined in the specification and salts thereof are disclosed. The compounds exhibit excellent antitumor activity and low toxicity and are useful as antitumor agents.
Patent TR-199801184-T2 (TR)
Inventor: ROBERTS EDWARD
IPC: C07D243/08
Filed: 1996-12-11
Abstract: Formül (I)'e sahip bilesikler, bunlarin farmasötik açidan tolare edilebilir tuzlari ve yeni bilesikleri içeren farmasötik preparatlar. Formül (I)'e sahip yeni bilesikler agri tedavisinde kullanilmaktadir.
Patent TR-199902590-T2 (TR)
Inventor: GASTER LARAMIE MARY
IPC: C07D409/12
Filed: 1998-04-14
Abstract: Formül (I) bilesimleri, bunlarin  hazirlanma prosesleri ve CNS maddeleri olarak kullanimlari açiklanmistir.
Patent DE-60014094-T2 (DE)
Inventor: JARCHAU MICHAEL
IPC: B01F5/06
Filed: 2000-07-06
Granted: 2005-03-17
Abstract: A homogenization valve includes a housing and stacked valve members within the housing. The valve members have central holes therethrough defining a low pressure volume. Each valve member includes a valve seat defining with a valve surface, gaps through which fluid is expressed radially from an outside high pressure volume to the central low pressure volume. The actuator acts on the valve members to control the width of the gaps. A counterbalancing mechanism reduces the amount of actuator force required to maintain a predetermined homogenization pressure.
Patent DE-60017524-T2 (DE)
Inventor: ERAMO LINCOLN JR
IPC: C08G59/40
Filed: 2000-10-17
Granted: 2005-12-29
Abstract: The invention provides an oligomer having tetraacrylate functionality which provides enhanced flexibility to photoimageable compositions which function as photoresists. The enhanced flexibility is particularly advantageous in epoxy-containing, solder mask-forming photoimageable composition, as this flexibility provides improved performance in nickel/gold plating.
Patent DE-60020107-T2 (DE)
Inventor: SCANDOLA MARIASTELLA
IPC: D06M15/53
Filed: 2000-07-05
Granted: 2006-01-26
Abstract: The present invention relates to polymer-grafted natural fibre used for the preparation of composite materials. The invention relates in particular to a process for making such polymer-grafted natural fibres.
Patent DE-60021278-T2 (DE)
Inventor: HUYBRECHTS JOSEF
IPC: C08F8/30
Filed: 2000-10-04
Granted: 2006-05-18
Abstract: Acrylic AB block copolymers prepared by group transfer polymerization that are useful as pigment dispersants, characterized by mononuclear or dinuclear heterocyclic groups bonded to the highly polar anchoring A segment of the block copolymer backbone to facilitate attachment on a pigment surface and improve dispersant efficiency in solvent-borne paint systems.
Patent DE-60021940-T2 (DE)
Inventor: GODO JOSEPH
IPC: A61B18/00
Filed: 2000-03-17
Granted: 2006-06-08
Abstract: The apparatus, using ultrasound for therapeutic purposes, consists of a transducer for emitting the ultrasound waves, located inside a chamber containing a liquid aqueous solution of a hydrophilic polymer as a connecting medium. The hydrophilic polymer has a molecular weight of between 10000 and 100000, and is used at a rate of 10 - 50 g/l. The transducer is connected to an ultrasound generator operating in the frequency range of 1 - 5 MHz, and preferably 2 - 3MHz.
Patent DE-60025218-T2 (DE)
Inventor: MURARO UMBERTO
IPC: E02F9/24
Filed: 2000-10-11
Granted: 2006-08-17
Abstract: A cab for earth-moving machines comprising a structure (2), a control station (3) for the operator defined within the structure (2), a safety bar (8) pivotally fastened internally to the structure (2) and movable from a safety position in which said bar (8) is positioned in front of the control station (3) and in which the operator is secured in the control station (3), to a non operative position, distanced from the safety position, in which the operator is free to move from the control station (3), and at least a control panel (9) of the machine mounted in the structure (2) and oriented towards the control station (3), integrally mounted on a portion (10) of the bar (8) oriented towards the control station (3) when the bar (8) is in the safety position. <IMAGE>
Patent DE-60030953-T2 (DE)
Inventor: GULACHENSKI JOSEPH A
IPC: A61M25/00
Filed: 2000-02-01
Granted: 2007-05-10
Abstract: A balloon catheter having a proximal end and a distal end and a main axial lumen extending therebetween is provided with an inflation seal such that the presence of a guidewire in the inflation seal forms a fluid-tight seal for retaining fluid in the balloon and causing inflation thereof. The inflation seal can be formed distally of the balloon or within the balloon. Marker bands disposed at the distal end a formed integrally with the structure of the balloon catheter.
Patent DE-60033528-T2 (DE)
Inventor: IDE SHOICHI
IPC: B01D67/00
Filed: 2000-08-18
Granted: 2007-11-15
Abstract: Filter membranes to be used in efficiently eliminating pathogens such as viruses from solutions of drugs or physiologically active substances employed as starting materials thereof which are contaminated with pathogens such as viruses. These filter membranes, which can simultaneously achieve favorable performance of eliminating small viruses and a high physiologically active substance-permeability, can be obtained by controlling the membrane characteristics to give a ratio (BP/ gamma ) of the bubble point BP (MPa) to the surface tension  gamma  (N/m) of 110 or above, and/or logarithmic elimination ratios of swine parvovirus at 0 to 5 l/m<2> filtration and at 50 to 55 l/m<2> filtration of each 3 or above, and regulating the permeability for bovine immunoglobulin, wherein the monomer content amounts to at least 80%, to 70% or above. These filter membranes make it possible to provide drugs or starting materials therefor with little fear of the contamination with viruses, etc. and, therefore, are useful in the fields of pharmacy, medicine and the like.
Patent DE-60034317-T2 (DE)
Inventor: SNOW ROBERT ALLEN
IPC: A61L31/18
Filed: 2000-02-25
Granted: 2008-01-03
Abstract: A medical or surgical device or tool that is designed to be implanted or inserted inside the human or mammalian body, having at least part of its surface coated whereby the ultrasound visibility of said device or tool in vivo is enhanced, wherein the coating comprises one or more of the following: (i) a matrix material containing a plurality of contrast enhancing elements; (ii) magnesium; (iii) a liquid or polymer which alters its ultrasound imaging properties upon elevating the temperature from ambient to physiological temperature; (iv) a liquid or polymer which alters its ultrasound imaging properties as a result of a change in pH; (v) an essentially non-polymeric bio-compatible compound which forms a discontinuous coating. Preferably the device or tool is a radioactive source for use in brachytherapy, and in particular a radioactive seed.
Patent DE-60035146-T2 (DE)
Inventor: ROGERS CHARLES H
IPC: C12M1/00
Filed: 2000-04-07
Granted: 2008-02-07
Abstract: An automated instrument and method for nucleic acid analysis is provided. The automated instrument is an integrated system including a sample processing station, a first reaction module, a second reaction module, a detection module and a control module for performing homogenous screening of broad specificity and multi-detection reactions on a nucleic acid test sample. The nucleic acid analysis performed in the instrument includes the steps of conducting a first test reaction using a low detection format, and if necessary, a selected second test reaction using a high detection format, detecting signals generated from the test reactions and processing signal data in a control module.
Patent DE-60036537-T2 (DE)
Inventor: DURING MATTHEW J
IPC: A61K35/76
Filed: 2000-02-22
Granted: 2008-06-19
Abstract: The invention provide methods and compositions for targeting endocrine cells capable of converting an immature expressed protein into a mature protein, and secreting the expressed protein into the systemic circulation. In particular, the invention features methods and compositions for treating disorders, such as diabetes by orally administering a vector expressing insulin to target cells which can subsequently secrete the expressed insulin into the blood circulation.
Patent DE-60100185-T2 (DE)
Inventor: GANCET CHRISTIAN
IPC: C07C67/08
Filed: 2001-06-05
Granted: 2004-01-29
Abstract: Production of esters by direct reaction of a carboxylic acid with an alcohol using a sulfonic acid catalyst is effected in the presence of a solid (I) having free tertiary amine functions.
Patent DE-60100865-T2 (DE)
Inventor: BONRATH WERNER
IPC: C07B61/00
Filed: 2001-03-10
Granted: 2004-07-29
Abstract: A process for the manufacture of (all-rac.)- alpha -tocopherol by the acid-catalyzed condensation of trimethylhydroquinone with isophytol or phytol is characterized by carrying out the condensation in the presence of a tris(perfluoroalkanesulphonyl or pentafluorobenzenesulphonyl)methane or a metal salt thereof as the catalyst in an organic solvent. In addition to said metal salt a Bronsted acid, e.g. sulphuric acid, phosphoric acid or p-toluenesulphonic acid, may be used as a co-catalyst. The product of the process is the most active member of the vitamin E group.
Patent DE-60103367-T2 (DE)
Inventor: EIVA TOMAS
IPC: B29C48/92
Filed: 2001-02-08
Granted: 2005-06-02
Abstract: The invention is a method for operating an extruder temperature controller. The method can include sensing an actual screw speed for an extruder screw in an extruder barrel. The extruder barrel has at least one heat exchange means. The method can then involve indexing and storing a plurality of screw speeds. Each of the stored screw speeds corresponds to a temperature reset value. Comparing the actual screw speed with each of the stored screw speeds can then be performed. Selecting one of the stored screw speeds can then occur. The selected screw speed is a member of the plurality of stored screw speeds having a value most arithmetically equivalent to the actual screw speed. The step of selecting retrieves the temperature reset value corresponding to the selected, stored screw speed. Generating a control output driver signal to the heat exchange means can occur. The control output driver signal is responsive to the retrieved temperature reset value. The invention includes delaying a control alarm for a predetermined time when generating a control output driver signal to the heat exchange means is at or near maximum capacity.
Patent DE-60105040-T2 (DE)
Inventor: MARKETZ FRANZ
IPC: B23K26/00
Filed: 2001-10-11
Granted: 2004-12-30
Abstract: The present invention relates to a method for interconnecting adjacent expandable pipes by Laser Beam Welding (LBW).
Patent DE-60109939-T2 (DE)
Inventor: ANDERSON DAVID
IPC: C07D493/04
Filed: 2001-08-23
Granted: 2006-01-19
Abstract: A process for the preparation of aromatic aldehydes containing fluorine, and more particularly, to a formylation process for fluorinated aromatic derivatives through the reaction of fluorinated benzenes with carbon monoxide and aluminum chloride at a relatively low pressure, a low temperature, and in the presence of at most a catalytic amount of an acid (such as aqueous hydrochloric acid) is herein disclosed. The resultant fluorinated benzaldehydes are useful as precursors to the formation of a number of different compounds, such as dyestuffs, flavorings, fragrances, herbicidal compounds, nucleating agents, polymer additives, and the like. The inventive method provides a very cost effective and safe procedure for producing such fluorinated benzaldehydes in very high yields.
Patent DE-60110118-T2 (DE)
Inventor: MUKHOPADHYAY TRIPTIKUMAR
IPC: A61K/
Filed: 2001-12-03
Granted: 2006-03-02
Abstract: The present invention relates to novel crystalline glucosamine sulphate metal salts for use in the treatment of acute and chronic forms of rheumatic and arthritic diseases and of all the pathological conditions originating from metabolic disorders of the osteo-articular tissues. More particularly, the present invention relates to novel crystalline glucosamine sulphate metal salts having low metal content wherein the metal may be either sodium or potassium. The present invention further relates to a solution-based and a solvent-free process for the preparation of the novel crystalline glucosamine sulphate metal salts having low metal content and to pharmaceutical compositions comprising the novel crystalline glucosamine sulphate metal salts having low metal content.
Patent DE-60119235-T2 (DE)
Inventor: LINTERN RICHARD
IPC: H01Q1/22
Filed: 2001-07-18
Granted: 2007-02-22
Abstract: A telecommunications card comprising a cavity in which an antenna structure is movably mounted between a first position in which the antenna structure is substantially located within the cavity and a second position in which the antenna structure is extended from the cavity, the telecommunications card further comprising moving means for moving the antenna structure from the first position to the second position, the antenna structure comprising a slide portion and an antenna portion which are movably connected to each other, characterised in that the antenna structure further comprises erecting means for erecting the antenna portion from the second position to a third position suitable for wireless communication with a telecommunications network. <IMAGE>
Patent DE-60124732-T2 (DE)
Inventor: TOKUSHIGE HIDEKI
IPC: A61K31/496
Filed: 2001-08-09
Granted: 2007-10-04
Abstract: A cytokine production inhibitor which comprises as an active component gatifloxacin, a hydrate thereof or a salt thereof.