baber/WOPTO huggingface dataset:
Patent DK-1567189-T3 (DK)
Inventor: THEISEN MICHAEL
IPC: A61P33/06
Filed: 2003-11-06
Granted: 2009-09-14
Abstract: The vaccine comprises chimeric malaria proteins derived from Plasmodium falciparum genetically coupled to Plasmodium falcinarum Merozoite surface protein 3. The vaccine is produced in Lactococcus lactis as a secreted recombinant hybrid protein. Experiments show that the Glutamate-rich protein part of the hybrid increases the overall antibody response. - Immunizations with the hybrid protein consistently generates a stronger antibody response against the individual Glutamate rich protein and Merozoite surface protein 3 domains than a mixture of the two recombinant molecules injected at one site or the individual recombinant molecules injected simultaneously at two different sites.
Patent DK-1597418-T3 (DK)
Inventor: VAN PARIDON HENK
IPC: D01F6/46
Filed: 2004-02-10
Granted: 2009-03-30
Abstract: The invention relates to fibres from heterophasic propylene copolymers having at least two Tg peaks. The fibres are characterised by excellent softness.
Patent DK-1611355-T3 (DK)
Inventor: JAEHN PETER
IPC: F04B43/00
Filed: 2004-03-31
Granted: 2011-01-31
Abstract: The invention relates to a diaphragm pump comprising a multi-part pump body that has at least three rigid plates and at least two elastic membranes placed between these plates. Said plates form at least one pump chamber and at least two blocking chambers, particularly with the geometry of a spherical segment of a spherical zone, of a cylinder or of a truncated cone, each having an inlet and outlet opening for the material to be delivered. The pump chamber and the blocking chambers, together with an inlet channel, form the connecting channels and together with an outlet channel, form a passage channel. The pump chamber and the blocking chambers are separated by the diaphragms into a product space and control space. The control spaces have control lines that are connected to a control unit. The invention is characterized in that the outer plate is provided with a stronger design whereby the control space of the pump chamber is enlarged, and an axially moving disc with an elongated rod, which is placed on one side, is inserted inside said control space.
Patent DK-1528948-T3 (DK)
Inventor: LEINEMANN CHRISTOPH
IPC: A62C4/02
Filed: 2004-06-26
Granted: 2007-02-26
Abstract: A flame arrestor for a flowing explosive gas ( 4 ), having a flame barrier ( 10, 20, 30 ) with a large number of defined passage gaps ( 17, 18 ), whose gap cross section is set with regard to the properties of the flowing gas ( 4 ), is cooled effectively and secured against a flame flashback in the case of continuous combustion by the fact that second gaps ( 18 ) having a smaller gap cross section are arranged adjacent to the first gaps ( 17 ) having the selected gap cross section.
Patent DK-1628663-T3 (DK)
Inventor: MULLAN MICHAEL J
IPC: A61K/
Filed: 2004-05-17
Granted: 2010-03-08
Abstract: The present invention provides methods for reducing β-amyloid deposition, β-amyloid neurotoxicity and microgliosis in animals or humans afflicted with a cerebral amyloidogenic disease, such as Alzheimer's disease (AD), by administering therapeutically effective amounts of the dihydropyridine calcium channel antagonist, nilvadipine. The present invention also provides methods for diagnosing cerebral amyloidogenic diseases in animals or humans. Further provided are methods for reducing the risk of β-amyloid deposition, β-amyloid neurotoxicity and microgliosis in animals or humans suffering from traumatic brain injury by administering nilvadipine immediately after the traumatic brain injury and continuing treatment for a prescribed period of time thereafter. Finally, methods are provided for treating transplantable neuronal stem cells by administering nilvadipine to the neuronal stem cells prior to transplantation in the central nervous system of an animal or human afflicted with a cerebral amyloidogenic disease, such as AD.
Patent DK-1667678-T3 (DK)
Inventor: GILLESSEN HUBERT JEAN MARIE FRANCOIS
IPC: A23L13/00
Filed: 2004-09-28
Granted: 2009-08-24
Abstract: Disclosed is an animal feed composition that comprises free indole acetic acid (free IAA) or a derivative thereof. Also disclosed is a method for enhancing animal growth by feeding the animal with a composition according to the invention. Further disclosed is the use of free IAA or a derivative thereof in a method of therapy of animals in need of a growth-promoting treatment, such as immunocompromised animals, animals with a growth deficit or slow-growing animals. Disclosed is the use of free IAA or a derivative thereof for the preparation of a therapeutical composition for increasing the growth rate and/or the feed conversion rate and/or the immunity of animals in need of such a treatment, in particular, immunocompromised or slow-growing animals. A composition may be in the form of a food or feed supplement.
Patent DK-1659112-T3 (DK)
Inventor: CAPET MARC
IPC: A61K31/444
Filed: 2005-10-18
Granted: 2007-10-15
Abstract: Arylpiperazine compounds (I) and their stereoisomers, tautomeric forms, hydrates, solvates, salts or esters are new. Arylpiperazine compounds of formula (I) and their stereoisomers, tautomeric forms, hydrates, solvates, salts or esters are new. R1 : heteroaryl with 5-6 chain links (optionally containing heteroatoms of 2-pyridyl, 2-pyrimidinyl, 2-pyridazinyl, 2-pyrazinyl, 2-imidazolyl, 2-oxazolyl, 2-thiazolyl, 3-isoxazolyl, 3-isothiazolyl, 1,2,4-triazol- 2-yl, 1,3,4-oxadiazol-2-yl or 1,3,4-thiadiazol-2-yl) (all optionally substituted by halo or OH), alkyl, monofluoroalkyl, polyfluoroalkyl, alkoxy, polyfluoroalkoxy, alkylsulfanyl or polyfluoroalkylsulfanyl group); Ar : (hetero)aryl (optionally fused with R1 and optionally substituted by halo or OH), alkyl, monofluoroalkyl, polyfluoroalkyl, alkoxy, polyfluoroalkoxy, alkylsulfanyl, polyfluoroalkylsulfanyl, CN, carbamoyl, dialkylcarbamoyl, alkyl-C(=O)-, alkyl-O-C(=O)-, HO-C(=O)-, (HO)alkyl group or fused with optionally saturated or aromatic hydrocarbon cycle or heterocycle; a : 2-4; b, c : 1-2; either R2-R6 : H, halo, OH, alkyl, monofluoroalkyl, polyfluoroalkyl, alkoxy, polyfluoroalkoxy, alkylsulfanyl, polyfluoroalkylsulfanyl, CN, -NRR-a, COOR, COR or CONRR-a group; R2+R3+R4+R5+R6 : hydrocarbon cycle or optionally saturated heterocycle (both are fused to the phenyl nucleus to which they are attached); and R, R-a : H or alkyl. Provided that compounds for which R1 is 2-oxazolyl, 2-imidazolyl or 2-thiazolyl fused to the Ar group (optionally substituted phenyl), and compounds for which R1 is 2-pyridyl group, fused to the Ar group phenyl (optionally substituted by CH3 in position 4 of the resultant quinoline cycle, a is 2, b, c are 1, R2 is H, OCH3 and R3-R6 is H or R2, R3 are Me and R4-R6 is H; R1 is 2-pyrimidinyl group, fused to the Ar group is phenyl substituted by OCH3 in positions 6 and 7 and -OH in position 4 or 6 of the resultant quinazolinyl cycle, a is 2, b, c are 1, R2-R5 are H and R6 is OCH3. Independent claims are also included for the preparations of (I). [Image] ACTIVITY : Neuroleptic; Antiaddictive; Endocrine-Gen.; Vasotropic; CNS-Gen.; Muscular-Gen.; Antiparkinsonian; Antidepressant. MECHANISM OF ACTION : Dopamine D3 receptor ligand. (I) were tested for dopamine D3 receptor ligand activity in HEK 293 cells. The inhibitory constant value of 2-{4-[4-(2,3-dichlorophenyl)piperazin-1-y l]butyl}amino-4-phenylpyridine was 0.55 nM.
Patent DK-1581038-T3 (DK)
Inventor: HEUSSI GEORG
IPC: H01R13/44
Filed: 2005-02-21
Granted: 2011-08-01
Abstract: A lift-in and lift-out device has a lift-in and lift-out device (1), a lift-in and lift-out grip (2), a bearing element (3) about which the lift-in and lift-out device rotates and a retention device with at least one retaining element (4) to hold the lift-in and lift-out grip (2) in a position suitable for plugging in the plug-in module. The retention element (4) is arranged in the region of the bearing element (3). Independent claims are included for the following (A) A plug-in module and (B) A sub-rack comprising at least one plug-in module.
Patent DK-1854662-T3 (DK)
Inventor: BARTH ROLAND
IPC: B60P1/32
Filed: 2006-05-11
Granted: 2010-09-20
Abstract: The vehicle (1) has a loading platform (2) with a projecting edge (24), where the platform is tiltably arranged in a frame (3). The platform is inversely pivotable from a horizontal transporting position to a suitable projecting position, where the edge of the platform is moved upward, when the platform is pivoted from the transporting position to the projecting position. The pivoting of the platform in the projecting position causes a horizontal movement of the projecting edge to a center of the frame.
Patent DK-1775199-T3 (DK)
Inventor: SAKAE AKIRA
IPC: B60J10/82
Filed: 2006-09-28
Granted: 2008-12-01
Abstract: A hollow panel includes a panel body and a guide rail member joined thereto. The panel body is formed in a structure such that two plate-like members are joined by many ribs. The panel body includes an open space portion and a closed space portion. The open space portion is formed so as to extend in the extrusion direction of the panel body and is formed as an open space in a cross-section perpendicular to the extrusion direction. The closed space portion has a shape such that a plurality of closed spaces are defined by the ribs between the plate-like members in a cross-section perpendicular to the extrusion direction. The guide rail member is press-fitted into the open space portion.
Patent DK-1937600-T3 (DK)
Inventor: BONNELYE VERONIQUE
IPC: B01D21/00
Filed: 2006-09-06
Granted: 2011-01-24
Abstract: The invention concerns a water clarifying device comprising a flotation zone (c), a membrane-based filtering zone (e) and extracting means (d), the flotation zone (c) and the membrane-based filtering zone (e) having a common partition wall (P), the common partition wall (P) including in its lower part an opening (o) directly allowing through flotated water towards the filtering zone (e), thereby feeding the membranes with flotated water from down upwards both in filtering phase and in backwashing phase.
Patent DK-1963212-T3 (DK)
Inventor: CORNELISSEN LEONARDUS ADRIANUS CATHARINUS
IPC: B65G17/08
Filed: 2006-12-19
Granted: 2010-11-22
Abstract: A conveyor, comprising a modular conveyor mat (2) driven by sprocket wheels (19), wherein the conveyor mat is driven by the sprocket wheel on the hinge pins (9). The modular conveyor mat comprises a number of modules (1) successive in conveying direction, which are each provided with a body part extending transversely to the conveying direction and having rows of hinge loops (6) reaching forward and rearward in the conveying direction, wherein the hinge loops of successive modules cooperate and are coupled using hinge pins.
Patent DK-1961821-T3 (DK)
Inventor: WEIK ROBERT
IPC: A61K38/18
Filed: 2007-02-22
Granted: 2009-10-12
Abstract: The present invention relates to recombinant fusion proteins wherein erythropoietin (EPO) is linked via its C-terminus to an Fc fragment, and wherein said recombinant fusion proteins are further carbamoylated at the primary amines of the fusion protein. More specifically the invention relates to carbamoylated EPO-Fc fusion proteins, wherein at least one, preferably two or more, lysine amine residues and/or the N-terminal amino acid of said fusion protein are carbamoylated. The carbamoylated EPO-Fc fusion proteins of the present invention having a reduced hematopoietic activity whereas the tissue regenerative activity, i.e. the nerval cell regenerative activity remains unaltered or is even enhanced as compared to unmodified EPO-Fc fusion proteins.  The invention further relates to a process for the manufacture of such fusion proteins and to pharmaceutical compositions containing them, as well as to the use of such fusion proteins and pharmaceutical compositions for medical therapy.
Patent DK-1881122-T3 (DK)
Inventor: LAHNI CHRISTIAN
IPC: E04B2/96
Filed: 2007-07-19
Granted: 2011-05-16
Abstract: The rail (1) has a screwing channel (2) for engaging self-cutting screws and including two channel flanks (3a, 3b) that are laid opposite to each other. One of the flanks is partially provided with a parallel groove structure (4) for perpendicularly guiding the screw during a screwing operation. The structure transversely extends to a longitudinal direction of the rail, and is formed by coining in the screwing channel. The structure includes grooves, where a cross section of each groove has a basic form of an equilateral triangle or trapezoid.
Patent DK-1865145-T3 (DK)
Inventor: WOOD CARL
IPC: E21B33/06
Filed: 2007-06-01
Granted: 2011-11-28
Abstract: The Invention provides an apparatus (1) and a method of substantially sealing a throughbore (3) of a tubular (2). The tubular (2) has a line (88) running therethrough. The method comprises the steps of: (a) substantially enclosing the line (88) and sealing a portion of the throughbore (3) around the line (88) using an enclosing means (58, 59); (b) injecting a fluid in the region of the line (88), wherein the fluid contains solid particles; and (c) substantially sealing a remaining portion of the throughbore (3) using the solid particles such that the sealed throughbore (3) is capable of withstanding a pressure differential. The method can include settling out the solid particles from the fluid in response to a drop in pressure of the fluid during step (b). The method can include injecting a first fluid in the region of the line (88) prior to step (b). The method can further include substantially sealing the remaining portion of the throughbore (3) according to step (c) using the first fluid and the solid particles. The first fluid can be a heavy hydrocarbon such as a grease and the fluid containing solid particles can be a drilling fluid.
Patent DK-2046292-T3 (DK)
Inventor: HASHASH AHMAD
IPC: A61K9/107
Filed: 2007-07-20
Granted: 2010-06-07
Abstract: Formulations are provided, comprising: a compound of Formula I, a pharmaceutically acceptable salt thereof, or a mixture of any two or more thereof; and an ingredient selected from a hydrophilic solvent, a lipophilic solvent, an emulsifier, or a mixture of any two or more thereof; wherein the compound of Formula I is: In some embodiments, the formulations are liquids. In other embodiments, the formulations are solids. Also provided are methods of preparing such formulations.
Patent DK-2037783-T3 (DK)
Inventor: BONNEL JOCELYN
IPC: A47J36/02
Filed: 2007-07-06
Granted: 2010-10-25
Abstract: The invention relates to a culinary article (100) having a bottom (101) in which heat-sensitive means (130) made of electrically conductive materials are placed. According to the invention, the heat-sensitive means (130) are made of non-ferromagnetic materials having a temperature-variable resistivity (p).
Patent DK-2094254-T3 (DK)
Inventor: CAVALLA DAVID
IPC: A61K31/135
Filed: 2007-12-05
Granted: 2011-10-03
Abstract: The present invention provides a means for prevention and treatment of cachexia and other chronic illnesses including but not limited to the promotion of weight gain, reduction or prevention of weight loss by administration of a substance that both reduces the sensitivity of beta-adrenergic receptors and of 5-HT1a receptors. (S)-pindolol, (S)-propranolol, tertatolol or bopindolol are preferred for this purpose.
Patent DK-2125021-T3 (DK)
Inventor: LEONARDI AMEDEO
IPC: A61K45/06
Filed: 2007-12-21
Granted: 2011-09-19
Abstract: The invention relates to a method of treating at least one symptom of lower urinary tract disease in a subject in need of treatment comprising administering to said subject a combination of an alpha<SUB>2</SUB>delta calcium channel subunit (A2d) ligand and a non-steroidal anti-inflammatory drug (NSAID), wherein the administered amounts of A2d ligand and NSAID together comprise a therapeutically effective amount of an active combination of agents. The combination of A2d ligand and NSAID can result in a synergistic therapeutic effect, wherein the combined effect is greater than the additive effect resulting from separate, single administration of A2d ligand or NSAID. Combination of A2d ligand and NSAID is particularly useful in treatment of lower urinary tract disease which manifests symptoms of urinary incontinence.
Patent DK-2248809-T3 (DK)
Inventor: SAITOH AKIHITO
IPC: C07D333/54
Filed: 2006-03-27
Granted: 2012-06-18
Abstract: The invention provides a process for production of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof characterized by subjecting 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propionyl)azetidin-3-ol to reduction reaction with an addition of activator in the presence of alkali metal borohydride.
Patent DK-0397048-T3 (DK)
Inventor: FLEMMING HANS-WOLFRAM DR
IPC: C07B61/00
Filed: 1990-05-04
Granted: 1994-11-21
Abstract: Process for the preparation of 2-mercapto-4-methyl-1,3-thiazol-5- ylacetic acid or its alkyl esters of the formula I <IMAGE>
Patent DK-0433740-T3 (DK)
IPC: G07C5/00
Filed: 1990-12-01
Granted: 1996-10-14
Abstract: The invention relates to a device for the administration of a multitude of vehicles driven by different users. To obtain quick, reliable administration of a multitude of vehicles using few personnel, a parking area (1) possessing an entrance (2) and an exit (2a) and having a data acquisition device for user access control is to be provided and also a receiving device (7, 7a) which is arranged in the region of the barrier (4, 4a) and receives vehicle operating data, such as mileage, tank contents, oil level and the like, transmitted from a transmitter fixed to the vehicle and informs a central control unit (10) which controls the barriers (4, 4a), the data acquisition device and the receiving device (7, 7a). With each entry and departure, all the operating data necessary for the beginning and end of a rental are thus communicated to the control unit (10), so that the settlement of the rental process can be dealt with by computer.
Patent DK-0435242-T3 (DK)
Inventor: BERTUS BRENT JOSEPH
IPC: C10G67/04
Filed: 1990-12-24
Granted: 1995-07-03
Abstract: Heavy hydrocarbon oil, containing asphaltene, sulfur and metal contaminants, is hydrotreated in the presence of a hydrotreating catalyst having a small pore diameter in an initial process step to remove sulfur and metal contaminants. Removal of additional metal and sulfur contaminants is then accomplished in a second process step by solvent deasphalting, wherein the size of the pore diameter of the hydrotreating catalyst utilized in the initial hydrotreating step affects the metals rejection in the subsequent solvent deasphalting step. In a third process step the deasphalted oil is catalytically cracked substantially in the absence of added hydrogen to provide lower boiling hydrocarbon products. <IMAGE>
Patent DK-0385555-T3 (DK)
Inventor: URLINGS LEONARDUS GERARDUS CAT
IPC: C02F3/02
Filed: 1990-02-27
Granted: 1993-12-06
Abstract: The invention provides an apparatus for carrying out a combined air and water purification comprising one or more compartments provided with inlets and outlets (1, 2, 4, 5, 6) and partially filled with biologically active material, which apparatus is constructed in a manner such that the air (2) (4) to be purified and the water (1) to be purified, optionally supplemented with additional air, are passed simultaneously through an aerobic biological system containing micro-organisms which are able to utilize organic compounds present as contamination as energy source and/or carbon source. The invention further provides a method for operating such a purification. Further nutrients such as nitrogen, phosphate and/or other trace elements can be added as required.
Patent DK-0443283-T3 (DK)
Inventor: LASNIER DIDIER
IPC: G05D16/10
Filed: 1990-12-27
Granted: 1994-08-15
Abstract: The body (1) of the pressure-reducing device comprises opposed bores (8, 9) for the mounting of means of connection for entry (34) and for exit (46) and the outer end of the bore (3) forming a high-pressure chamber in which the regulation valve (7) is mounted is arranged to receive a means of connection (40) of a high-pressure manometer (41) forming a bearing surface for the spring (39) for loading the regulation valve (7), which comprises a frustoconical annular fitting (37) in which is force-fitted the rod (38) for coupling between the regulation valve (7) and the piston (13) delimiting the low-pressure chamber (12). 
<??>Application to various arrangements of pressure-reducing devices for industrial use. 
<IMAGE>
Patent DK-0490920-T3 (DK)
Inventor: GERGELY THOMAS
IPC: A61K31/715
Filed: 1990-09-06
Granted: 1994-04-25
Abstract: PCT No. PCT/EP90/01503 Sec. 371 Date Mar. 6, 1992 Sec. 102(e) Date Mar. 6, 1992 PCT Filed Sep. 6, 1990 PCT Pub. No. WO91/03241 PCT Pub. Date Mar. 21, 1991.Granules, possibly pressed into the form of tablets, contain at least one insoluble, complexed or slightly soluble active substance in powder form which can bind or neutralize acids and which does not react with the acid of the effervescent system, and an effervescent system consisting of at least one organic, edible acid and at least one alkali metal and/or alkaline earth metal carbonate and/or bicarbonate. The active substance is present in an amount of 5 to 50, preferably 8 to 30, in particular 12 to 25%, by weight. It has an acid binding power of 2 to 40, preferably 3.5 to 25, meq/g, does not react with the acid of the effervescent system and increases the pH in 0.1N HCl during 2 min by a maximum of 0.5. It consists in particular of magnesium trisilicate, sucralfate and/or a bismuth salt. Each granule contains at least one acid component, at least one carbonate component and at least one active substance bound to one another. Binding of the granule components to one another is effected by a reaction product of an acidic with a carbonate component and/or by at least one hydrocolloid, in particular xanthan, maltodextrin, galactomanan and/or tragacanth.
Patent DK-0451911-T3 (DK)
Inventor: VROUWENVELDER CURINUS CORNELIS
IPC: A21C9/00
Filed: 1991-04-05
Granted: 1994-03-14
Abstract: The invention relates to an apparatus for adjusting the length of dough strands, comprising a receiving gutter, V-shaped in cross-section, whose walls are defined by elements which engage a dough strand placed in the gutter at regularly spaced apart locations along the length of the dough strand and can exert axial forces thereon. According to the invention, the elements which define the walls of the receiving gutter (3) and engage the dough strands (10) are formed by rolling members (4,4a) arranged with interspaces and adapted to be driven progressively and selectively from the middle (X-X) of the gutter in either direction, and support members (9) which convey the strands transversely of the gutter (3) are arranged between the rolling members (4,4a). The mutual arrangement of the gutter (3) and of the support members (9) is variable, at least as to the relative level. <IMAGE>
Patent DK-0448191-T3 (DK)
Inventor: GRIES HEINZ DR
IPC: A61K49/10
Filed: 1991-03-18
Granted: 1995-11-20
Abstract: 1,4,7,10-Tetraazacyclododecane-butyltriols of the general formula IA <IMAGE>  in which   R<1> independently of one another denotes hydrogen or a metal ion equivalent and   R<2> denotes a butyltriol radical, and their salts with organic or inorganic bases or amino acids are useful pharmaceutical agents.
Patent DK-0513465-T3 (DK)
Inventor: RATERA PORTELLA ELISEO
IPC: D04C3/14
Filed: 1991-07-17
Granted: 1995-12-27
Abstract: The spool carrier has a turntable (7) with a lower annular cavity (23) equipped with inner teeth (24), into which the first arm of a lever (22) tends to be snapped by means of a torsion spring (25); the second arm is connected to a metal wire (21) wound on the guide column (13) below and above the wire-guide support (20), in such a way that when the latter is subjected to a tension of the wire, it rises until it pulls the upper end of the metal wire (21) which with its lower end pulls the lever (22) which unsnaps the teeth (24) from the turntable (7), thereby bringing about the free pivoting of said turntable (7) and of the wire spool (26). A helical spring (16) keeps the wire guide (20) downwards by means of a rod (18); if said rod (18) is removed, this spring (16) can be replaced by another. <IMAGE>