baber/WOPTO huggingface dataset:
Patent CA-2554609-A1 (CA)
Title: Derives d'heteroaryl-alkylcarbamates, leur preparation et leur application comme inhibiteurs de l'enzyme faah
Inventor: BARTSCH-LI REGINE
IPC: C07C271/10
Filed: 2005-02-25
Abstract: Composé répondant à la formule générale (I):dans laquelle A est choisi parmi un ou plusieurs groupes X, Y et/ou Z ; X représente un groupe méthylène éventuellement substitué ; Y représente un C2-alcènylène éventuellement substitué ou un C2-alcynylène ; Z représente un groupe C3-7~cycloalkyle ; n représente un nombre entier allant de 1 à 7 ; R1 représente un groupe de typ e naphtalènyle ou hétéroaryle éventuellement substitué ; R7 représente un atom e d'hydrogène ou un groupe C1-6-alkyle ; R8représente un atome d'hydrogène ou un groupe C1-6-alkyle, C3-7-cycloalkyle, C3-7-cycloalkyle-C1-3-~alkylène ; à l'état de base, de sel d'addition à un acide, d'hydrate ou de solvat.Ces composés ont une activité inhibitrice sur l~enzyme FAAH.
Patent CA-2556483-A1 (CA)
Inventor: BROWN LEE S
IPC: G09F7/18
Filed: 2006-08-21
Abstract: A signage system includes an alpha-numeric character with angled front walls defining a peaked internal cavity and having perimeter flanges extending along edges of the front walls. A mount plate fits into and is hidden by the character.  Connectors releasably attach the character to the mount plate. Features on the mount plate and character inter-engage to center and align the character on the mount plate.  The connectors can be snap-attach, hook-and-loop, or magnetic. Alternatively, adhesive can be used to attachment.
Patent CA-2558337-A1 (CA)
Inventor: ANDERSON FRED JAY
IPC: H01Q3/02
Filed: 2005-03-21
Abstract: A configurable antenna system and method of implementing is disclosed, having particular use with a wireless access point of the type used with a wireless local area network. The antenna system includes an antenna arrangement for selectively varying between first and second operational positions. In the first operational position, the antenna arrangement operates in an omni-directional antenna mode. In the second operational position, the antenna arrangement operates in a directional antenna mode. A signal reflecting member is further provided for cooperating with the antenna arrangement in the second operational position, to substantially establish the antenna arrangement in a directional configuration.
Patent CA-2559511-A1 (CA)
Inventor: PELAGIO GREGG
IPC: H02G3/08
Filed: 2005-03-18
Abstract: L'invention concerne un capuchon protecteur (8) destiné à adhérer à un substrat. Le capuchon protecteur comprend une feuille de base sensiblement plate (10), un dôme (15) s'étendant vers l'extérieur à partir d'un côté avers de la feuille de base et formant une cavité sur le côté opposé de la feuille de base, ladite cavité étant dimensionnée pour encapsuler sensiblement un connecteur (37). Le capuchon comprend également un blindage semi-tubulaire (20) qui s'étend vers l'extérieur à partir d'un côté de la feuille de base et délimite sur le côté opposé de la feuille de base un canal s'étendant de la cavité à la périphérie de la feuille de base. Le capuchon comprend en outre une couche primaire intégrée (30) présentant un adhésif autocollant et fixée au revers de la feuille de base pour s'appliquer sur le substrat.
Patent CA-2563377-A1 (CA)
Title: Methods of using and compositions comprising pde4 modulators for the treatment and management of pulmonary hypertension
Inventor: ZELDIS JEROME B
IPC: A61K31/519
Filed: 2005-04-21
Abstract: Methods of treating, preventing and managing pulmonary hypertension are disclosed. Specific methods encompass the administration of a PDE4 modulator, or a pharmaceutically acceptable salt, solvate (e.g., hydrate), stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active agent, surgery and/or lung transplantation. Specific second active agents are capable of reducing pulmonary artery pressure. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.
Patent CA-2563600-A1 (CA)
Inventor: TAKAHASHI MASAHIDE
IPC: C04B35/478
Filed: 2005-04-28
Abstract: Disclosed is a magnesium aluminum titanate crystal structure which has excellent heat resistance, excellent thermal shock resistance, high thermal decomposition resistance and high mechanical strength and thus can be stably used at varying high temperatures. Also disclosed is a method for producing such a magnesium aluminum titanate crystal structure. Specifically, such a magnesium aluminum titanate crystal structure is characterized by being composed of a solid solution wherein Al atoms are partially substituted with Si atoms in at least the surface layer of the magnesium aluminum titanate crystal structure having a chemical composition: MgxAl2(1-x)Ti(1+x)O5 (wherein 0.1 <= x < 1), by having a thermal expansion coefficient between -6 × 10-6 (1/K) and 6 × 10-6 (1/K) when heated to 50-800~C at a heating rate of 20~C/minute, and by having a residual ratio of magnesium aluminum titanate of not less than 50% when maintained in the atmosphere at 1,100~C for 300 hours.
Patent CA-2564149-A1 (CA)
Title: Water flow control system and apparatus
Inventor: WHITE JILL
IPC: A63J17/00
Filed: 2006-10-03
Abstract: A water flow control system and apparatus is disclosed. The system comprises a water distribution system configured to deliver water from a water source to a water amusement apparatus. At least one detector is coupled with the water distribution system to detect a change in the water being distributed from the water source to the water amusement apparatus. An effect generator is responsively coupled with the detector such that when the detector detects a change in the water, the effect generator produces at least one effect. The apparatus adaptable for use with a water distribution system comprises at least one detector configured to detect changes in water being distributed through the water distribution system and an effect generator responsively coupled with the detector such that when the detector detects a change in the water, the effect generator produces at least one effect.
Patent CA-2565059-A1 (CA)
Title: Procede de traitement d'eau pure
Inventor: BOURGARD FABRICE
IPC: C02F1/36
Filed: 2005-05-13
Abstract: L'invention concerne un procédé de traitement d'eau pure. Il consiste, après avoir obtenue une eau ultra pure, à la traiter par cavitation dans une cuve équipée d'une antenne acoustique (3) comportant des transducteurs piézoélectriques de type Tonpilz qui émettent au moins à la fréquence d'excitation des molécules d'eau avec une puissance acoustique permettant de dépasser le seuil de cavitation compte tenu de la quantité d'eau à traiter.
Patent CA-2565259-A1 (CA)
Inventor: ADELMAN BURT
IPC: A61K38/17
Filed: 2005-05-09
Abstract: Methods of treating viral disorders are disclosed.
Patent CA-2566190-A1 (CA)
Title: Use of targeted oxidative therapeutic formulation in treatment of age-related macular degeneration
Inventor: HOFMANN ROBERT F
IPC: A61K31/045
Filed: 2005-05-10
Abstract: A pharmaceutical formulation and its use. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by an oxygen-containing oxidizing agent, such as ozone; a penetrating solvent, such as dimethylsulfoxide ("DMSO"); a dye containing a chelated metal, such as hematoporphyrin; and an aromatic redox compound, such as benzoquinone. The pharmaceutical formulation is used to effectively treat patients affected with age-related macular degeneration ("ARMD").
Patent CA-2566981-A1 (CA)
Title: Lentille ophtalmique pour limiter la fatigue visuelle des porteurs esophores et non presbytes
Inventor: DELDALLE BENEDICTE
IPC: G02C7/02
Filed: 2005-05-31
Abstract: Une lentille ophtalmique présente une surface complexe, avec une méridienne sensiblement ombilique et une progression de sphère moyenne supérieure ou égale à 0,50 dioptrie et inférieure à 0,75 dioptrie. La lentille est prescrite aux porteurs ésophores et non presbytes. La lentille est prescrite comme une lentille unifocale classique. Du fait de la présence de la progression de sphère moyenne, le porteur accommode moins en vision de près, ce qui compense son ésophorie.
Patent CA-2571522-A1 (CA)
Inventor: GEIGER MARTIN
IPC: F23N1/02
Filed: 2005-06-20
Abstract: The temperature generated by a firing apparatus, particularly a gas burner, depends on the mixing ratio between the quantity of air and the quantity of gas fed to the firing apparatus, characterized by the excess air coefficient .lambda., at a predefined burner load (air mass flow rate) in such a way that the temperature generated by the firing apparatus reaches a maximum when .lambda.=1.  According to the inventive method for adjusting the excess air coefficient, said maximum temperature T max is determined, whereupon the desired setpoint value .lambda.hy of the excess air coefficient is adjusted and the associated setpoint temperature T soll is measured. A  characteristic curve which represents the correlation between the respective air mass flow rates and the setpoint temperatures at the setpoint value .lambda.hy of the excess air coefficient and allows combustion to be regulated to an optimal hygienic state can be determined from said determined correlation between the setpoint temperatures T soll at different predefined burner loads. The inventive firing apparatus is adapted to carry out said method and especially comprises a mass flow sensor in the air delivery zone as well as a temperature sensor in the effective range of the burner flame.
Patent CA-2572825-A1 (CA)
Title: Compositions for multi-step delivery of hot-spots radiation to cancer cells
Inventor: CHIN HSIAO-LING
IPC: A61K39/00
Filed: 2005-07-25
Abstract: The invention features compositions and methods for treating or alleviating a symptom of cancer. The compositions and methods of the invention direct supra-lethal doses of radiation, called Hot-Spots, to virtually all cancer cell types.
Patent CA-2575878-A1 (CA)
Title: Creation of diversity in polypeptides
Inventor: BEIER LARS
IPC: C12N9/28
Filed: 2005-08-02
Abstract: The inventors realized that the diversity generated by conventional methods may be limited by steric hindrance between amino acid residues in the three-dimensional structures of the resulting polypeptides. The steric hindrance may occur between amino acid residues at widely different positions in the amino acid sequences, e.g. between residues in two different domains of the 3D  structure, and resulting polypeptides which include such steric hindrance may never be observed in the conventional recombination methods because they may be expressed in poor yields or may have poor activity or stability. The inventors developed a method to identify and alleviate such steric hindrance in the resulting polypeptides. In an alignment of the three-dimensional structures, steric hindrance is indicated when residues from two different structures are located within a certain distance. Pairs of residues at corresponding positions in the amino acid sequences are not considered, and residues close to the surface (high solvent accessibility) are considered to be less prone to steric hindrance.
Patent CA-2576407-A1 (CA)
Title: Substituted phenylacetamides and their use as glucokinase activators
Inventor: FYFE MATTHEW COLIN THOR
IPC: C07D241/20
Filed: 2005-08-09
Abstract: Compounds of Formula (I) wherein R1 is a cycloalkylsulphonyl group, or pharmaceutically acceptable salts thereof, are useful in the prophylactic and therapeutic treatment of hyperglycemia and diabetes.
Patent CA-2576479-A1 (CA)
Title: Apparatuses and methods for separating mixed materials
Inventor: KERKERA DEREK
IPC: C13B10/06
Filed: 2007-01-30
Abstract: An apparatus includes a separation deck free of stepwise changes in elevation between a first end and a second end, the separation deck comprising a plurality of spaces through which a constituent material may pass, a plurality of scrubbers disposed on the deck, the plurality of scrubbers having a first end disposed at a higher elevation than the deck in at least a first state, and a vibratory generator coupled to the deck. The mixed material moves over the deck and the scrubbers from the first end to the second end by the motion imparted by the vibratory generator. Components of the mixed material move relative to each other as the components move over the scrubbers, thereby causing the constituents material attached to the components of the mixed material to separate and pass through the spaces in the separation deck.
Patent CA-2577005-A1 (CA)
Title: Multi-sport swing training apparatus
Inventor: BEGERT DAVID L
IPC: A63B67/00
Filed: 2005-08-12
Abstract: A multi-sport training apparatus for teaching and improving hitting and throwing skills, including an adjustable waist belt with a buckle; a resilient connector having a distal end and a proximal end, two clamps disposed on the waist belt such that when said waist belt is worn at least one clamp is located near the iliac crest of the user's leading hip and may be employed for adjustably capturing and retaining the proximal end of the resilient connector, a swivelable clip disposed on the distal end of said resilient connector, and a sports implement/hand connector having a hook for attachment to the clip. Also disclosed is a method of using the apparatus to teach hitting and throwing skills
Patent CA-2578589-A1 (CA)
Inventor: HSU EDWARD CHING-SHEN
IPC: C10G17/00
Filed: 2005-08-30
Abstract: This invention is a method for reducing the total acid number of organic acid containing petroleum oil comprising forming a water-in-oil emulsion comprising an aqueous Group IIA metal hydroxide solution or slurry in a hydrocarbon oil, said water-in-oil emulsion having an aqueous droplet particle size diameter of from 1 to 25~, adding the water-in-oil emulsion to the organic acid containing petroleum oil and permitting the mixture to stand for a time sufficient to permit the neutralization of the organic acids in the petroleum oil.
Patent CA-2580469-A1 (CA)
Inventor: GAUCHEROT JACQUES
IPC: H04M1/724
Filed: 2005-08-30
Abstract: The inventive self-adhesive and sealed device having a deformable structure enables, for example, a skier provided with a portable cellular telephone (a) connected to a transmission/reception interface (b) and to an earphone/microphone set (c) to transmit or receive telephone calls without taking off his gloves and without handling the portable telephone thereof. The keyboard is fixable to a support (a vehicle panel board, a motorcycle tank, clothes, on a flat part of ski) by means of an adhesive element ( 1 ) disposed on the lower face of a flexible pad ( 2 ). The pad is sealingly covered by an elastic shell ( 3 ) which comprises large keys ( 4 ) and a transparent window on the external face thereof. The sealed chamber which is formed by the pad and shell contains a battery, an electronic system for transmitting and receiving signals allocated to the interface of the portable telephone of a user and electric connections for said components. The anti-thief device of the keyboard is intrinsic in such a way that the keyboard is useless without the interface associated to the portable telephone.
Patent CA-2580616-A1 (CA)
Title: Treatment of defects of cellular immunity with leukocyte homogenates having a molecular weight of less than 10,000 dalton
Inventor: SALAMA ZOSER B
IPC: A61K35/15
Filed: 2005-09-26
Abstract: The invention relates to a composition consisting of proteins, peptides and/or peptide constituents, a pharmaceutical product containing said composition, a method for producing said composition, and the use thereof for the prophylaxis or therapy of people and/or patients with pathogenic modifications and/or defects of cellular immunity, especially cancer, sepsis or allergic reactions, in conjunction with cytostatic therapy, chemotherapy and/or radiotherapy.
Patent CA-2580764-A1 (CA)
Title: Atraumatic connections for multi-component stents
Inventor: THISTLE ROBERT C
IPC: A61F2/90
Filed: 2005-08-31
Abstract: A stent is provided that includes at least two stent segments which mate with one another. At least one of the stent segments includes a hollow member, and at least one of the stent segments includes a solid member. At least one of the solid members is secured to at least one of the hollow members.
Patent CA-2585383-A1 (CA)
Title: Substituted 5-oxo pyrazoles and [1,2,4]triazoles as antiviral agents
Inventor: COOPER ALAN B
IPC: C07D409/12
Filed: 2005-10-26
Abstract: The present invention provides compounds of formula (I) wherein X and R1-R7 are as defined herein. Compositions containing these compounds, and methods for inhibiting HCV RNA-dependent RNA polymerase and treating hepatitis C and related disorders using these compounds and compositions are also provided.
Patent CA-2587366-A1 (CA)
Inventor: SHIM DONG-HEE
IPC: H04B7/26
Filed: 2005-12-05
Abstract: A method of canceling a location information request is disclosed, in which if a location server having received a location information request about a specific terminal from an external client is unable to forward location information of the terminal to the external client, the location server can cancel the location information request without a cancellation request from the external client. The location information request cancellation message may be selected among a Triggered Location Report message or a Triggered Location Reporting Stop Answer message or among a Standard Location Immediate Report message or a Standard Location Immediate Stop Answer message according to a location information request message.
Patent CA-2592589-A1 (CA)
Title: Integrated preparation and separation process
Inventor: MULDER DOMINICUS FREDERICUS
IPC: C07D301/32
Filed: 2005-12-27
Abstract: Integrated preparation and separation process comprising a preparation process wherein a byproduct is produced; and a gas separation process wherein a first component is separated from a mixture of components by diffusion of the first component through a porous partition into a stream of sweeping component;  wherein the byproduct produced in the preparation process is subsequently used as the sweeping component in the separation process, and an industrial set-up for use in such a process.
Patent CA-2595110-A1 (CA)
Inventor: MAIER STEPHAN
IPC: A61F15/00
Filed: 2005-11-09
Abstract: A card-shaped primary packaging unit for a plurality of flat administration forms containing active substances comprises a central web (1) made of a rigid packaging material, a top web (2) made of a thin film, a bottom web (2) made of a thin film, and a plurality of dosage units (4) which remain individually packaged even one of the administration forms (4) is removed from the packaging unit.
Patent CA-2595371-A1 (CA)
Title: System and method for allocating prescriptions to non-reporting outlets
Inventor: COPELAND KENNON
IPC: G06Q30/00
Filed: 2005-12-07
Abstract: A method for predicting market information for a plurality of pharmaceutical outlets includes the steps of receiving first data representing purchases and sales of at least one pharmaceutical product from at least one pharmaceutical outlet over a time period in the past, calculating the amount of prescriptions that are not reported in a timely manner at a product-level, computing a product-level projection factor for the at least one pharmaceutical product and using the product level projection factor to estimate the unreported amount of prescriptions.
Patent CA-2596446-A1 (CA)
Title: Infrastructure health monitoring and analysis
Inventor: GARABEDIAN ARMINEH
IPC: G01M99/00
Filed: 2007-08-08
Abstract: There is described herein a method for detecting anomalies in an infrastructure, the method comprising: providing a computationally-intelligent analysis model to model a behaviour of at least one detection instrument in said infrastructure; inputting control instrument data into said analysis model, said control instrument data being provided by control instruments in said infrastructure; outputting an estimated behaviour for said at least one detection instrument from said analysis model; comparing actual data from said at least one detection instrument to said estimated behaviour and generating a set of residuals representing a difference between said actual data and said estimated behaviour; and identifying anomalies when said residuals exceed a predetermined threshold.
Patent CA-2600186-A1 (CA)
Inventor: MEHTA VINAY
IPC: H05B37/02
Filed: 2007-09-05
Abstract: A ventilation fan and light (10) is disclosed which includes a housing (12) and a light kit (13). The housing (12) includes an air intake 15 adjacent the light kit and an air exhaust port (16) coupled to an exhaust duct (17).  The light kit has one or more light sources (20). A  motorized fan (19) is mounted within the housing. The motorized fan is operated at a low speed whenever the light source is illuminated and a high speed whenever ventilation is required. The operation of the fan at a low speed prevents the build-up of heat within the housing. The ventilation fan includes an electric circuit (22) which includes a capacitor mounted between a light source electrical branch (23) and a fan motor electrical branch (24).
Patent CA-2602932-A1 (CA)
Title: Fcc process combining molecular separation with staged conversion
Inventor: SWAN GEORGE A III
IPC: C10L1/02
Filed: 2006-03-10
Abstract: This invention relates to fluid catalytic cracking (FCC) process for improving the quality of distillates suitable as blend stocks for diesel fuels. The FCC  process combines staging the FCC conversion process with interstage molecular separation of multi-ring aromatic species. Lower and higher severity reaction zones in the riser of the FCC reactor are combined with selective molecular separations to improve the production of diesel quality distillates.
Patent CA-2604038-A1 (CA)
Title: New tricyclic angiotensin ii agonists
Inventor: WU XIONGYU
IPC: A61P1/00
Filed: 2006-04-12
Abstract: There is provided compounds of formula (I) wherein the dotted line, X1, X2, X3, A, Y1, Y2, Y3, Y4, Z1, Z2, R2 and R3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful as selective agonists of the AT2 receptor, and thus, in particular, in the treatment of inter alia gastrointestinal conditions, such as dyspepsia, IBS and MOF, and cardiovascular disorders.
Patent CA-2604575-A1 (CA)
Inventor: MATSUMORI AKIRA
IPC: G01N33/53
Filed: 2006-04-11
Abstract: The invention relates to the following [1] to [3] methods and a kit for carrying out the methods. [1] A method for detecting heart disease, characterized by assaying kappa-chains and/or lambda-chains of free immunoglobulin light chains in an analyte and comparing at least any one of a value of the kappa-chains, a value of the lambda-chains and a kappa/lambda ratio to a corresponding value of a normal subject. [2] A method for detecti ng complications of viral infection in heart disease, characterized by assaying kappa-chains and/or lambda-chains of free immunoglobulin light chains in an analyte and comparing at least any one of a value of the kappa-chains, a val ue of the lambda-chains and a kappa/lambda ratio to a corresponding value of a normal subject. [3] A method for detecting the severity of heart disease, characterized by assaying kappa-chains and/or lambda-chains of free immunoglobulin light chains in an analyte and comparing at least any one of a value of the kappa-chains, a value of the lambda-chains and a kappa/lambda ratio to a corresponding value of a normal subject or a patient with mild heart disease.
Patent CA-2604603-A1 (CA)
Title: Novel cyclic amines
Inventor: RICKLIN FABIENNE
IPC: C07D401/14
Filed: 2006-04-24
Abstract: The invention is concerned with novel cyclic amines of formula (I) wherein X1 to X3, Y1 to Y3, R1~ , R1~~ and n are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments.