baber/WOPTO huggingface dataset:
Patent CA-2994091-A1 (CA)
Inventor: ENDO KYOKO
IPC: A61P9/04
Filed: 2016-08-01
Abstract: The present invention addresses the problem of providing: a novel peptide which can exert the medicinal effect or efficacy thereof rapidly and has a long duration of remission; and a medicine and an external preparation, particularly a prophylactic or therapeutic agent for dermatitis, rough skin, rhinitis, alopecia or thinning hair, a hair growth agent, an anti-depilation agent, an antipruritic agent, a skin care product and the like, each of which contains the peptide. According to the present invention, the problem can be solved by providing a cyclic peptide comprising the amino acid sequence represented by formula I wherein the amino acid sequence does not contain a peptide bond other than peptide bonds formed between amino acid residues that constitute the amino acid sequence, or a derivative of the cyclic peptide, or a pharmaceutically acceptable salt of the cyclic peptide or the derivative.
Patent CA-2994224-A1 (CA)
Title: Agent therapeutique pour le cancer du tractus biliaire
Inventor: MATSUI JUNJI
IPC: A61P35/00
Filed: 2016-08-17
Abstract: La présente invention concerne un agent thérapeutique pour le cancer du tractus biliaire qui comprend le 4-[3-chloro-4-(cyclopropylaminocarbonyl)aminophénoxy]-7-méthoxy-6-quinolinecarboxamide ou un sel pharmacologiquement acceptable de celui-ci.
Patent CA-2994987-A1 (CA)
Inventor: BROWN CARL OSCAR III
IPC: C07C66/02
Filed: 2016-08-17
Abstract: L'invention concerne des procédés et des compositions visant à inhiber l'expression des protéines ASC et NLRP3, et/ou la formation d'un complexe, l'inflammasome NLRP3, à l'aide de la diacéréine ou de ses analogues. L'invention concerne également des méthodes et des compositions utilisant la diacéréine ou ses analogues en vue du traitement et/ou de la prévention d'un trouble à médiation par la protéine ASC et/ou NLRP3, et/ou par la formation du complexe de l'inflammasome NLRP3.
Patent CA-2995755-A1 (CA)
Inventor: JAECKEL CHRISTIAN
IPC: A23C20/02
Filed: 2016-08-31
Abstract: Variants of chymosin with improved a S1-casein cleavage and C/P properties.
Patent CA-2997752-A1 (CA)
Title: Industrial fan housing assembly with replaceable scroll
Inventor: PREIS FRED
IPC: F04D29/40
Filed: 2018-03-01
Abstract: There is disclosed an industrial fan housing assembly, comprising: a plurality of scroll-liner sections configured to be assembled together to form a midsection of the industrial fan housing assembly, each scroll-liner section including a liner; wherein, each scroll-liner section includes side flanges to assemble the section to first and second fan housing scroll sideplates on either side. In an embodiment, at least two of the plurality of scroll-liner sections are identical and interchangeable, thereby allowing the identical and interchangeable sections to be assembled in one of a plurality of positions. Advantageously, the scroll-liner sections may be installed without welding or cutting, and may be individually removed for servicing or replaced when the lining is worn. The cost for operating and servicing and the fan housing assembly is significantly reduced.
Patent CA-2998037-A1 (CA)
Inventor: LORD CHRISTOPHER
IPC: A24F40/50
Filed: 2014-10-08
Abstract: An electronic vapour provision system includes a vaporiser for vaporising liquid for inhalation by a user of the electronic vapour provision system. The system also includes a power supply comprising a cell or battery for supplying power to the vaporiser and a power regulation system for compensating for variation in the voltage level of the power supplied to the vaporiser by the power supply using pulse-width modulation, thereby providing a more consistent output level of vaporised liquid for inhalation by the user.
Patent CA-3002637-A1 (CA)
Title: Vehicule d'enlevement du fumier servant a enlever le fumier d'un plancher d'abri pour animal
Inventor: VAN DEN BEUKEL HUIBRECHT JOHANNES ARJEN
IPC: A01K1/01
Filed: 2016-09-19
Abstract: La présente invention concerne un véhicule d'enlèvement de fumier à roues pour enlever du fumier du plancher de l'étable d'un animal, comprenant un réservoir pour stocker le fumier, un moyen de collecte du fumier, un réservoir de liquide (30) placé dans le réservoir et ayant une ouverture (35) pour l'alimentation en liquide du réservoir (30) et l'évacuation de liquide depuis le réservoir (30), et une paroi de réservoir souple (31, 38) pour pouvoir faire varier le volume du réservoir (30) selon le niveau de remplissage, et un moyen de distribution qui est raccordé fonctionnellement avec le réservoir (30) pour distribuer du liquide depuis le réservoir (30) sur le plancher de l'étable d'un animal. L'ouverture (35) du réservoir (30) est située dans la partie supérieure du réservoir (30). Le réservoir (30) comprend en outre un moyen d'entretoise (40) qui s'étend sur l'intérieur du réservoir (30) à partir de l'ouverture (35) vers le bas jusqu'à la partie inférieure du réservoir (30) pour assurer un passage de liquide entre l'ouverture (35) et une partie inférieure du réservoir (30).
Patent CA-3005712-A1 (CA)
Title: Plaquette de fraisage tangentiel triangulaire et outil de fraisage
Inventor: DAGAN DANIEL
IPC: B23C5/06
Filed: 2016-10-30
Abstract: La présente invention concerne une plaquette de fraisage tangentiel réversible et indexable comprenant deux surfaces principales et une surface périphérique qui s'étend entre celles-ci. La plaquette de fraisage comprend un plan médian (M) situé à mi-chemin entre les surfaces principales, et un trou de serrage de plaquette comportant un axe (H) central de trou. La surface périphérique comprend trois surfaces latérales, chacune comprenant exactement deux parties de coupe, deux parties de dépouille et deux surfaces de butée secondaires situées sur des côtés opposés du plan médian (M), chacune s'étendant de façon continue entre la partie de coupe et la partie de dépouille correspondantes. Chaque partie de coupe comprend un bord de coupe principal, un bord de coupe secondaire, et un bord de coupe de coin. Dans une section transversale le long d'un premier plan imaginaire perpendiculaire à l'axe (H) de trou, chaque surface de butée secondaire est incurvée de manière concave, et sur chaque surface latérale, les surfaces de butée secondaires convergent vers l'extérieur.
Patent CA-3006086-A1 (CA)
Title: Method employing bispecific protein complex
Inventor: FINNEY HELENE MARGARET
IPC: C07K16/46
Filed: 2016-12-01
Abstract: The present invention is directed to a method of controlling and directing cells, for example to stimulate an immune response, inhibit an immune response, direct tissue regeneration or prevent tissue damage for therapeutic activity through the use of heterodimerically-tethered bispecific protein complex of formula A-X:Y-B. Component A may present X on the surface of a cell, may bind a protein (including a marker) expressed on the surface of an effector cell, or A-X is expressed on the surface of an effector cell, whilst B is specific to an epitope on target cell or tissue of interest. X:Y is a heterodimeric-tether which is formed by a binding interaction between X and Y, which together with A and B assists and effects the controlling and directing of the selected cells.
Patent CA-3006146-A1 (CA)
Title: Complexe antibiotique fiirv 104/18 et facteurs individuels isoles de ce dernier
Inventor: CARRANO LUCIA
IPC: C12N1/20
Filed: 2016-11-24
Abstract: L'invention concerne un complexe antibiotique FIIRV 104/18 comprenant les facteurs F793, F795, F797, F813 et F683, de formule (I), (I) où R représente un radical glycosidique tel que défini dans la description, les facteurs individuels isolés, leur procédé de production par culture de Dactylosporangium FIIRV sp. 104/18 DSM 32068 en conditions aérobies, et des formulations pharmaceutiques les contenant comme principe actif ainsi que leur utilisation dans le traitement d'infections bactériennes provoquées par des bactéries d'au moins un des genres suivants : entérocoques, streptocoques, staphylocoques et Moraxella, dont des bactéries de souches multirésistantes, en particulier les Staphylococcus spp., Streptococcus spp. et Enterococcus spp. résistants à la méthicilline et/ou la vancomycine.
Patent CA-3006160-A1 (CA)
Inventor: HUFFER SCOTT WILLIAM
IPC: B65D47/36
Filed: 2018-05-25
Abstract: The present invention relates to a composite container which has a bottom film layer and a top film layer at least partially adhered on its lower surface to the upper surface of the bottom film layer. The top film layer is scored to form at least one resealable flap and at least one pull tab continuous with the resealable flap, wherein the resealable flap is resealably adhered to the bottom film layer and the pull tab is not adhered to the bottom film layer. The bottom film layer comprises at least one cavity opening. A cardboard layer is adhered on its lower surface to the upper surface of the top film layer, wherein the cardboard layer has at least one cavity opening which is substantially aligned with the scoring of the top film layer resealable flap and the cardboard layer is perforated to form at least one pull tab which is substantially aligned with and adhered, on its underside, to the upper surface of the top film layer pull tab.
Patent CA-3006449-A1 (CA)
Inventor: SODO DIEGO
IPC: E03C1/23
Filed: 2016-11-23
Abstract: The present invention relates to a multiple draining system (1;100-121) for sinks or wash-basins mainly for domestic use. In particular, the invention is relative to a draining system provided with a simple and reliable construction which allows to recover wastewater from sinks or basins when it is desired to use it for further processing or other direct uses. The system comprises means for diverting (5, 32-33) wastewater flow alternatively to a sewage system and to a recovery system, by means of a control (4;13; L; 13a; 611; 692) positioned above the level of the bottom (A) of the basin for collecting water.
Patent CA-3006698-A1 (CA)
Inventor: SCHILLER PETER
IPC: C07K5/08
Filed: 2016-11-29
Abstract: Compositions comprising an antioxidant directed or indirectly conjugated to an aromatic-cationic peptide are provide. Said antioxidants are selected from TEMPO, Tro, PBN, AHDP, DBHP, Caf and Hem and may be conjugated to the aromatic-cationic peptide directly or indirectly via a linker to the N-terminus, C-terminus or a side chain of an amino acid residue of the aromatic-cationic peptide. In some embodiments, the aromatic-cationic peptide is 2',6'-Dmt-D-Arg-Phe-Lys-NH2, Phe-D-Arg-Phe-Lys-NH2 or D-Arg-2',6'-Dmt-Lys-Phe-NH2. These conjugates have increased antioxidant activity as compared to the unconjugated aromatic-cationic peptide and have utility in treating complex regional pain syndrome.
Patent CA-3007582-A1 (CA)
Inventor: SAND JANNIE MARIE BULOW
IPC: G01N33/574
Filed: 2017-01-20
Abstract: A method of immunoassay for detecting in a biological sample a fragment of collagen type VII alpha 1 comprising an N- or C-terminal neo-epitope, the method comprising contacting the biological sample comprising the fragment of collagen type VII alpha 1 comprising the N- or C-terminal neo-epitope with an antibody of the invention, and determining the amount of binding of the antibody
Patent CA-3007906-A1 (CA)
Title: Process for producing a phosphorus product from wastewater
Inventor: AZARNOUSH FAZLOLLAH
IPC: C02F1/66
Filed: 2016-12-21
Abstract: The present invention concerns a process for producing a high purity phosphorus product from wastewater, by carrying to the process phosphate-containing wastewater that has been treated to remove biomass and other impurities, not including dissolved phosphates, creating floes using one or more iron, aluminium, magnesium or calcium salts, adding an alkali metal or alkaline earth metal hydroxide or oxide to the flocs in an amount effective to react the iron, aluminium, magnesium or calcium salt into the corresponding hydroxide, separating the hydroxide from the formed phosphate, and obtaining the high purity phosphorus product in a form of a liquid or solid phosphate salt.
Patent CA-3009540-A1 (CA)
Title: Rotary hydraulic pump with esp motor
Inventor: REEVES BRIAN PAUL
IPC: F04B1/14
Filed: 2016-12-27
Abstract: A submersible pumping system (100) includes an electric motor (110) and a pump (108) driven by the electric motor. The pump (108) includes a rotatable shaft (122) driven by the motor, one or more piston assemblies (132) configured for linear reciprocating motion and a mechanism for converting the rotational movement of the shaft to linear reciprocating movement in the piston assemblies. In one aspect, the mechanism for converting the rotational movement of the shaft includes a tilt disc assembly (134). In another aspect, the mechanism for converting the rotational movement of the shaft includes a camshaft assembly.
Patent CA-3010677-A1 (CA)
Title: Nitrogen based hydrogen sulfide scavengers and method of use thereof.
Inventor: SUBRAMANIYAM MAHESH
IPC: C10L3/10
Filed: 2016-12-23
Abstract: The present invention relates to a hydrogen sulphide scavenging additive composition for scavenging hydrogen sulphide including sulfur containing compounds and mercaptans, particularly for scavenging hydrogen sulfide in hydrocarbons, wherein the additive composition comprises substantially reduced amount of nitrogen based hydrogen sulfide scavengers, and is also required in substantially reduced amount, and wherein the additive composition scavenges the sulfur containing compounds not only at room temperature, but also at higher temperatures, and comprises at least a combination of: (A) at least one nitrogen based hydrogen sulfide scavenger; and (B) at least one aliphatic tertiary amine, wherein the nitrogen based hydrogen sulfide scavenger comprises triazine based hydrogen sulfide scavenger. In one embodiment, it also relates to a method for scavenging hydrogen sulfide in hydrocarbons, and in another embodiment it relates to a method of using an additive composition of the present invention for scavenging hydrogen sulfide in hydrocarbons. In yet another embodiment, it relates to a composition comprising (i) a hydrocarbon and (ii) a hydrogen sulfide scavenging additive composition for scavenging hydrogen sulfide in hydrocarbons.
Patent CA-3012938-A1 (CA)
Title: Stable linewidth narrowing of a coherent comb laser
Inventor: LU ZHENGUO
IPC: H01S5/06
Filed: 2018-07-31
Abstract: A technique for narrowing a linewidth of a plurality of lines of a coherent comb laser (CCL) concurrently comprises providing a mode-locked semiconductor coherent comb laser (CCL) adapted to output of at least 4 mode-locked lines; tapping a fraction of a power from the CCL  from the laser cavity to form a tapped beam; propagating the tapped beam to an attenuator to produce an attenuated beam; and reinserting the attenuated beam into the laser cavity, where the reinserted beam has a power less than 10% of a power of the tapped beam. The reinsertion allows the CCL to be operated to output the mode-locked lines, each with a linewidth of less than 80% of the original linewidth. By propagating the tapped and attenuated beams on a solid waveguide, and ensuring that the secondary cavity is polarization maintaining, improved stability of the linewidth narrowing is ensured.
Patent CA-3013613-A1 (CA)
Inventor: CRUSON BRIAN
IPC: F16L33/32
Filed: 2018-08-08
Abstract: A hose clamp, for clamping a pneumatic seed delivery hose within a slotted receiver tube of an agricultural seed boot, including a clamping band with thread elements for cooperation with a screw within a fastener housing at one end of the clamping band to be clamped circumferentially about the hose within the receiver tube. A set of claws are spaced apart from one another along opposing sides of the fastener housing for penetration into the pneumatic seed delivery hose when clamping the hose within the receiver tube.
Patent CA-3014197-A1 (CA)
Inventor: KUMAR RAVINDRA
IPC: C07K16/46
Filed: 2017-02-22
Abstract: Disclosed herein are ActRII antagonists and methods for increasing immune responses and/or activity in patients in need thereof including, for example, cancer patients. In some embodiments, the disclosure relates to methods for treating cancer and/or tumors in a patient comprising administration of an ActRII antagonists and a PDl-PDLl antagonist.
Patent CA-3016215-A1 (CA)
Inventor: ENGQVIST HAKAN
IPC: A24F40/465
Filed: 2017-02-28
Abstract: There is provided an inhalation device for delivering a deliverable agent in the form of an aerosol or vapour to a user. The device comprises a solid, porous carrier material having a defined porosity, and a deliverable agent located within the pores of the carrier material. The device is operable to heat the carrier material and vaporise the deliverable agent. Deliverable agents that may be delivered to the user include nicotine. Suitable materials for the porous carrier material include chemically bonded ceramic materials and geopolymeric materials.
Patent CA-3021583-A1 (CA)
Inventor: MOCHEV STEFAN
IPC: B29C65/14
Filed: 2017-05-05
Abstract: La présente invention concerne un procédé pour le soudage d'un premier corps façonné (1a) avec un deuxième corps façonné (1b). À cette fin, on utilise un outil (5), qui présente une première face externe (6a) et une deuxième face externe (6b), la première face externe (6a) comprenant un canal (7a) et la deuxième face externe (6b) comprenant un canal (7b). L'extrémité (2a) du premier corps façonné (1a) est chauffée par un gaz chaud alors que l'extrémité (2a) se trouve à une distance (Xa) située dans la plage de 3 mm à l'extérieur du canal (7a) jusqu'à 10 mm à l'intérieur du canal (7a) par rapport au plan (14a) d'entrée dans le canal. De même, la surface de jonction (6b) du deuxième corps façonné (1b) est chauffée par un gaz chaud alors que l'extrémité (2b) se trouve à une distance (Xb) située dans la plage de 3 mm à l'extérieur du canal (7b) jusqu'à 10 mm à l'intérieur du canal (7b) par rapport au plan (14b) d'entrée dans le canal. Ensuite, l'extrémité (2a) chauffée et la surface de jonction (2b) chauffée sont mises en contact l'une avec l'autre, refroidies et un joint de soudage est formé entre le premier corps façonné (1a) et le deuxième corps façonné (1b). La présente invention concerne en outre le corps façonné soudé, pouvant être obtenu au moyen du procédé selon l'invention.
Patent CA-3022173-A1 (CA)
Inventor: RABASCO JOHN J
IPC: C09D7/65
Filed: 2018-10-26
Abstract: The present invention relates to a composition comprising an aqueous dispersion of acrylic based polymer particles; less than 15 PVC of a pigment; and a hydrophobically modified poly(oxyalkylene-urethane) rheology modifier having a hydrophobic portion represented by Structure I: (see structure I) Where R, R1, R2, m an n are defined herein. The composition provides viscosity stability for paint formulations containing a HEUR rheology modifier.
Patent CA-3023200-A1 (CA)
Title: Rail transport system
Inventor: WYATT STEPHEN
IPC: B65G67/42
Filed: 2017-05-05
Abstract: A rail transport system 10 has at least two load carrying bodies 12 which are arranged end to end. Mutually adjacent bodies 12 are coupled together by respective coupling systems 14. The rail transport system 10 further includes a plurality of axles 16 each provided at opposite ends with respective rail wheels 18 which support the bodies 12. A flexible liner 20 is supported by the bodies 12. The liner 20 is configured to span respective coupling systems 14. In this way the bodies 12 and the flexible liner 20 form a continuous load carrying structure 22. The continuous load carrying structure 22 is arranged so as to be able to pivot about an axis perpendicular to the axles 16 to facilitate unloading of cargo from the bodies 12.
Patent CA-3025860-A1 (CA)
Inventor: DI FIORE PIER PAOLO
IPC: C12Q1/68
Filed: 2017-06-19
Abstract: The present invention relates to refined prognostic clinical tools, methods, and kits for the evaluation of risk and treatment of distant recurrence in ER+/HER2- breast cancer patients.
Patent CA-3026001-A1 (CA)
Title: Dispositif et systeme de mesure de debit de fluide
Inventor: MAHALINGAM SAKETHRAMAN
IPC: G01F1/684
Filed: 2017-06-07
Abstract: La présente invention concerne un dispositif de mesure du débit d'un fluide. Le dispositif comprend un élément chauffant, un boîtier et un détecteur. L'élément chauffant est situé à l'intérieur dudit boîtier, le boîtier définissant un premier trajet thermique de l'élément chauffant à une première région de l'extérieur du boîtier et un deuxième trajet thermique de l'élément chauffant à une deuxième région de l'extérieur du boîtier. Le détecteur est configuré pour détecter une propriété associée au transfert de chaleur de l'élément chauffant vers l'extérieur du boîtier. Le premier trajet thermique a une première conductivité thermique et le deuxième trajet thermique a une deuxième conductivité thermique. La première conductivité thermique est supérieure à la deuxième conductivité thermique. La première région de l'extérieur du boîtier est plus petite que la deuxième région de l'extérieur du boîtier.
Patent CA-3026776-A1 (CA)
Inventor: MAYRPETER JOHANNES
IPC: B65B69/00
Filed: 2017-07-11
Abstract: The invention relates to a decanting device for decanting material from a flexible bulk material container, wherein the decanting device has a hollow body (2) that has an upper opening face and a lower opening face, wherein the upper end of the hollow body (2) projects into the interior of the flexible bulk material container so that material from the flexible bulk material container can enter the hollow body (2) via the upper opening face of the latter, wherein at the lower end of the hollow body (2) there is a closure that has an upper plate (4) and a lower plate (5), wherein the lower plate (5) can be pivoted about the axis of a bolt (8), from a first position in which it completely closes the opening of the upper plate (4) to a second position in which the opening of the upper plate (4) is at least slightly open, wherein the lower plate (5) has a structure (12) that forms at least part of the standing face of the decanting device, wherein the bolt (8) does not extend downward past the standing face.
Patent CA-3028771-A1 (CA)
Inventor: STONE EVERETT
IPC: C12N15/60
Filed: 2017-07-06
Abstract: Cette invention concerne des procédés et des compositions relatifs à la modification d'une protéine avec une activité enzymatique de dégradation de la L-cyst(é)ine. Par exemple, selon certains aspects, l'invention peut concerner une cystathionine-y-lyase modifiée comprenant une ou plusieurs substitutions d'acides aminés et capable de dégrader la L-cyst(é)ine. De plus, selon certains aspects, l'invention concerne des compositions et des procédés de traitement du cancer avec une L-cyst(é)ine au moyen des protéines ou des acides nucléiques de l'invention.
Patent CA-3029119-A1 (CA)
Inventor: LUNDBERG ANTE SVEN
IPC: C12N9/22
Filed: 2017-06-22
Abstract: The present application provides materials and methods for treating a patient with one or more condition associated with FXN whether ex vivo or in vivo. In addition, the present application provides materials and methods for editing and/or modulating the expression of FXN gene in a cell by genome editing.
Patent CA-3030246-A1 (CA)
Inventor: GLAZE AMANDA
IPC: D06N7/00
Filed: 2017-06-27
Abstract: Disclosed are tufted carpet structures, including synthetic turf structures, such as synthetic grass structures, that include a polyurethane backing coating formed from a polyether carbonate polyol.
Patent CA-3035309-A1 (CA)
Inventor: MILLET AGUILAR-GALINDO OSCAR
IPC: A61P7/00
Filed: 2017-10-27
Abstract: The present invention relates to the use of the compound ciclopirox or a pharmaceutically acceptable salt or solvate thereof for the treatment and/or prevention of congenital erythropoietic porphyria (CEP).