baber/WOPTO huggingface dataset:
Patent CA-2377446-A1 (CA)
Title: Increased sensitivity of peptide detection with matrix-assisted laser desorption/ionization mass spectrometry by in vacuo methylation of amino groups
Inventor: KAPLAN HARVEY
IPC: G01N33/68
Filed: 2002-03-20
Abstract: The invention relates to a method of detecting peptides having amino groups.  The method involves digesting a protein into at least two peptides having an amino group.  The amino groups are trimethylated under vacuum and then the peptides are detected using mass spectrometry. Another embodiment of the invention provides a method of detecting peptides. The method employs a protein having a lysine residue having an .epsilon.-amino group. The protein is digested into at least two peptides. The .epsilon.-amino group is then trimethylated under vacuum. The peptides are then detected using mass spectrometry. The method can also be used for a protein having an .alpha.-amino group.  Alternatively, a method of detecting peptides is provided for a protein having a lysine residue where the lysine residue has an .epsilon.-amino group. The protein is digested into at least two peptides having an .alpha.-amino group. The .alpha.-amino group and .epsilon.-amino group are trimethylated under vacuum and the peptides are detected using mass spectrometry.
Patent CA-2378579-A1 (CA)
Inventor: PLATT NANCY J
IPC: C12Q1/68
Filed: 2000-07-07
Abstract: A method for treating silage to enhance aerobic stability by inhibiting growth of yeast strains associated with spoilage of silage is disclosed. The method comprises treating silage or feed with a composition comprising killer yeast strains, or the antimicrobial components produced thereby. According to the invention, strains of <i>Saccharomyces exiguus</i> have been purified and isolated which are nontoxic, safe, do not assimilate lactate and which improve aerobic stability of silage, are disclosed. Portions of these strains have been sequenced to further characterize the invention.
Patent CA-2379339-A1 (CA)
Inventor: DUNWOODY STEVEN A
IPC: C03B37/018
Filed: 2000-06-20
Abstract: A method is disclosed for recovering germanium from a gaseous mixture which includes a germanium-containing compound in vapor or particulate form, acid in vapor form, and water vapor. The gaseous mixture is contacted with a liquid containing water under conditions effective to dissolve the germanium-containing compound in the liquid. The acidity of the resulting liquid mixture is increased under conditions effective to vaporize the germanium-containing compound. The vaporized germanium-containing compound is contacted with one or more aqueous solutions under conditions effective to dissolve and precipitate the germanium-containing compound in at least one of the one or more aqueous solutions, and the resulting precipitate is separated from the at least one of the one or more aqueous solutions. The methods described herein are particularly well suited for recovering germanium from the waste gases produced during optical waveguide manufacturing processes. Germanium recovered by this method can thereafter be used in the production of semiconductors, optical waveguide fibers and optical components.
Patent CA-2379884-A1 (CA)
Title: Apparatus and method for separating particles from a cyclonic fluid flow
Inventor: CONRAD WAYNE E
IPC: A47L9/16
Filed: 2000-07-26
Abstract: A particle separation member (40) is provided for use with a cyclone separat or (30). The particle separation member (40) divides the separator (30) into a cyclone chamber (46) and a particle receiving chamber (50). The cyclone chamber (46) and the particle receiving chamber (50) communicating via a plurality of apertures (52) in the particle separation member (40).
Patent CA-2380851-A1 (CA)
Title: Process for catalyzing the oxidation of organic compounds
Inventor: BERNARDELLI PATRICK
IPC: C07B35/04
Filed: 2000-08-09
Abstract: Oxidation of organic compounds is catalyzed by addition of a catalytic amount of a metalloporphyrin in a non-reactive aprotic solvent.
Patent CA-2382628-A1 (CA)
Inventor: THOMAS JUDITH M
IPC: A61K31/567
Filed: 2000-04-14
Abstract: The present invention provides a method of inducing immune tolerance to a graft in a recipient, comprising administering to the recipient an immunotoxin, thereby reducing the recipient's T-cell population; and administering to the recipient an agent that inhibits dendritic cell maturation. The present invention also provides a method of screening for an agent that acts synergistically with an immunotoxin in inducing immune tolerance and a method of screening for an agent that inhibits dendritic cell maturation. The present invention also provides a method of treating a subject with an autoimmune disease, comprising administering to the subject an immunotoxin, thereby reducing the subject's T-cell population; and administering to the subject an agent that inhibits dendritic cell maturation. Also provided herein is a composition comprising an immunotoxin and an agent that inhibits dendritic cell maturation.
Patent CA-2382754-A1 (CA)
Inventor: NASHEF AWS
IPC: A61B18/08
Filed: 2000-08-25
Abstract: Cette invention a trait à un cathéter pourvu d'un dispositif de transfert de chaleur placé au niveau de son extrémité distale ou à proximité de celle-ci, ce dispositif de transfert de chaleur se présentant en couches sur ou dans la paroi du cathéter ou la revêtant. Ce dispositif de transfert de chaleur consiste, de préférence, en un film souple surmonté de circuits d'acheminement de résistance électrique ou renfermant ceux-ci, ce film pouvant également être directement déposé sur la paroi du cathéter par le biais d'un processus de dépôt. Dans une variante, ce dispositif peut être constitué par une longueur de la paroi du cathéter et fait, totalement, quasiment ou partiellement, d'un matériau dopé capable d'agir comme dispositif de transfert de chaleur une fois excité. Ce dispositif de transfert de chaleur est excité, de préférence, par un ou plusieurs fils métalliques co-extrudés dans le corps de cathéter.
Patent CA-2382900-A1 (CA)
Title: Simulated stone texture process
Inventor: KURIGER KURT
IPC: B29C41/22
Filed: 2002-04-22
Abstract: Simulated stone texture products are obtained when specially selected materials are properly admixed and formed via molding techniques. These products are manufactured from suitable molds according to a prescribed process methodology using synthetic polymeric materials instead of stone materials. Prerequisite surface textures are produced that effectively simulate the corresponding actual stone products.
Patent CA-2385176-A1 (CA)
Inventor: AZAMI NAWFEL
IPC: G02B6/02
Filed: 2002-05-07
Abstract: A method of adjusting thermal dependence of an optical fiber involves hydrogenating the fiber to render it photosensitive, and then exposing it to UV radiation for such time period as to achieve the desired adjustment in the thermal dependence. In an all-fiber Mach-Zehnder interferometer, the method involves using a photosensitive fiber as one of the arms of the interferometer and exposing this photosensitive fiber to UV radiation so as to adjust the thermal dependence of the interferometer. The resulting interferometer is also part of the invention.
Patent CA-2386393-A1 (CA)
Title: Purified antigen for alzheimer's disease, and methods of obtaining and using same
Inventor: ZINKOWSKI RAYMOND P
IPC: G01N33/68
Filed: 2000-06-16
Abstract: Disclosed are a preparation comprising Alzheimer's disease antigen (A68), methods of obtaining this purified antigen, and methods of using this purified antigen, for instance, for diagnosing Alzheimer's disease and for detecting human autoantibodies to the Alzheimer disease antigen. The antigen preparation according to the invention is purified in that it is substantially free of immunoglobulin G. The invention further relates to methods of making Alzheimer disease antigens that can be used instead of or along with the A68 antigen preparation (e.g., for diagnosing AD), such as recombinant human tau, tau isolated from various species including human, and phosphorylated recombinant human tau or isolated tau, as well as A68 anti-idiotypic antibodies.
Patent CA-2386399-A1 (CA)
Title: Devices and techniques for a posterior lateral disc space approach
Inventor: FREY GEORGE
IPC: A61F2/46
Filed: 2000-10-23
Abstract: This invention relates to methods and instruments for performing disc space preparation and implant insertion from a unilateral approach to the spine through a posterior lateral opening to the disc space. The instruments include spreaders, distractors, reamers, scrapers, cutters, chisels, pushers and implant inserters. A surgical procedure is provided that allows bilateral support of the adjacent vertebrae with at least one interbody fusion device inserted into the disc space via a unilateral approach. Implants for insertion into the disc space are also provided.
Patent CA-2387413-A1 (CA)
Inventor: MELHUISH ROBERT A
IPC: E05F1/12
Filed: 2002-05-24
Abstract: A hinge used to mount a door to an overhead storage cabinet is disclosed. The hinge provides a combination linear and articulated motion to provide the clearance between the door of the cabinet and the upper, outer corner of the cabinet.  Further, the hinge provides a user assist on the opening of the cabinet door and a self-dampening motion on the closing of the cabinet door without the use of pneumatic cylinders.
Patent CA-2387955-A1 (CA)
Title: Animal carrier
Inventor: RICHMOND EDWARD
IPC: A01K1/02
Filed: 2000-11-10
Abstract: A pet carrier (10), expandable to hold a pet and collapsible to suitcase size, includes a pair of platforms (12, 14) and first and second pairs of spaced walls (16, 18, 20, 22). The first walls (e.g. front, rear) are pivotably attached at opposite ends to the platforms and are hinged at intermediate positions for collapsing or opening the carrier.      The second walls (e.g. side) are pivotable toward an individual one of the platforms, with the platform as a fulcrum, to collapse the carrier and are pivotable toward the other platform to open the carrier.      Resilient members (30) at the bottom of the first walls releasably engage the second walls for maintaining the carrier open. The resilient members are constrained to provide for a pivotal movement of the second walls to the carrier's open relationship. Straps (56a, 56b) engage clasps (48) on the top platform in different relationships providing for a manual transport of the carrier by the pet owner.
Patent CA-2388456-A1 (CA)
Title: Macroaggregated albumin-polyethyleneimine (maa-pei) lung-targeted delivery of respiratory syncytial virus dna vaccines
Inventor: TRIPP RALPH
IPC: C12N15/87
Filed: 2002-05-31
Abstract: The present invention provides a composition comprising: 1) macroaggregated albumin, 2) a nucleic acid comprising a nucleotide sequence encoding an RSV  protein, and 3) polyethylamine (PEI), wherein the MAA, PEI and nucleic acid form a complex.  Also provided by the present invention is a method of preventing respiratory syncytial virus (RSV) infection in a subject comprising administering to the subject an amount of a composition of this invention.
Patent CA-2388937-A1 (CA)
Title: Non-aqueous or low-water suspension concentrates of mixtures of active compounds for crop protection
Inventor: SIXL FRANK
IPC: A01N47/36
Filed: 2000-10-11
Abstract: The invention relates to stable liquid and highly effective suspension concentrates comprising a) one or more solid herbicidally active compounds from the group of the sulfonylureas in suspended form, b) one or more active compounds which are partially or completely dissolved in component c), c) an organic solvent or solvent mixture, d) one or more nonionic emulsifiers, e) optionally one or more ionic emulsifiers, f) optionally one or more thickeners or thixotropic agents and no water or up to 30 percent by weight of water in dissolved form.
Patent CA-2388985-A1 (CA)
Title: Enhanced herbicides
Inventor: COLEMAN ROBERT
IPC: A01N37/04
Filed: 2000-10-13
Abstract: The invention provides, improved herbicide compositions, methods of making the compositions and methods of controlling plant growth. The subject invention relates to combining fatty acid based and other herbicides with succinic acid, succinic acid derivatives and other additives such as those having essentially no herbicidal activity to increase the activity of the herbicide and provide methods of controlling plant growth by applying a combination of a herbicidal fatty acid with succinic acid and/or succinic acid derivative chemicals and/or other additives. In addition to the use of succinic acid, combining other Krebs cycle acids with herbicides can also provide beneficial effects.  Concentration of herbicides and additives applied to plants in accordance with the invention can include compositions involving 0.1 to 30 % herbicide, preferably 0.5 to 15 % herbicide and additive and more preferably 1-8 %  herbicide. The ratio of herbicide, such as fatty acid herbicide to activity enhancing additives can be from 1:10 to 20:1, preferably 1:1 to 20:1, most preferably 1:1 to 5:1.
Patent CA-2393351-A1 (CA)
Title: Dense refractory material for use at high temperatures
Inventor: DE NORA VITTORIO
IPC: F27D27/00
Filed: 2000-12-06
Abstract: A component is made of or coated with a refractory material for use at high temperature, e.g. in an aluminium production cell, an arc furnace or an apparatus for treating molten metal. The refractory material comprises particles of a refractory metal compound selected from metal borides, silicides, nitrides, carbides and phosphides, in an oxide matrix. The oxide matrix comprises a bonding mixed oxide made of a single mixed oxide or a plurality of miscible mixed oxides. The refractory material is obtainable fr om a heat treated slurry that comprises: a colloidal and/or polymeric oxide carrier, suspended particles of the refractory metal compound and suspended metal oxide particles. The suspended refractory metal compound particles and  the suspended metal oxide particles are both reactable with the colloidal and/or polymeric oxide to form the bonding mixed oxide.
Patent CA-2393919-A1 (CA)
Title: Methods for optimizing and evaluating network access techniques
Inventor: CAHN ROBERT
IPC: H04L1/24
Filed: 2002-07-18
Abstract: Methods of evaluating access to Virtual Private Networks (VPNs) from alternate access connections and for improving access to VPNs from alternate access connections such as ISPs. The methods include downloading a set of tests through a network backbone to simulate access to the VPN from the alternate access connection and comparing the results of the test to benchmarks for the test of access to the VPN from leased lines and modems. By obtaining comparisons of the tests and the benchmarks, it is possible to determine the throughput of data through the VPN and tell the customer how its access connections are affecting, among other things, the raw data throughput. This allows the customer and/or the network service provider to adjust the access connections to improve communications with the VPN.
Patent CA-2394789-A1 (CA)
Title: Proteases
Inventor: YAO MONIQUE G
IPC: A61P43/00
Filed: 2000-12-19
Abstract: L'invention concerne des protéases (PRTS) humaines, ainsi que des polynucléotides permettant d'identifier ces PRTS et codant pour ces dernières. L'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. L'invention concerne en outre des méthodes de diagnostic, de traitement ou de prévention des troubles associés à une expression aberrante de PRTS.
Patent CA-2395293-A1 (CA)
Title: Optical scheme for high flux low-background two-dimensional small angle x-ray scattering
Inventor: JIANG LICAI
IPC: G01N23/201
Filed: 2000-12-18
Abstract: An x-ray analysis system including a focusing optic for focusing an x-ray be am to a focal point, a first slit optically coupled to the focusing optic, a second slit optically coupled to the first slit, and an x-ray detector, wher e the focal point is located in front of the detector.
Patent CA-2396295-A1 (CA)
Inventor: HECKEL DONALD T JR
IPC: A47C1/024
Filed: 2001-01-05
Abstract: Three mechanical locks (60, 130, 180) are part of a mechanism for adjusting and dumping a vehicle seat. A master mechanical lock (60) attaches to the se at back. When it is unlocked, depending on the condition of the other locks, on e can adjust or dump the seat. A dumping mechanical lock (130) also attaches t o the seat back through an intermediary of a slave mechanical lock (180). When  the dumping mechanical lock is unlocked, a connection to the master mechanic al lock (60) also opens that lock to allow the seat back to dump.
Patent CA-2396978-A1 (CA)
Title: Uv curable transparent conductive compositions
Inventor: KROHN ROY C
IPC: C08F2/46
Filed: 2001-01-11
Abstract: The present invention discloses an ultraviolet light curable transparent conductive composition and method for mak-ing such a composition that may be used to produce a transparent conductive coating on a suitable substrate. These coatings may be used in such applications as touch screens, membrane switches, TV screens, and VCRs. The disclosed composition does not contain any significant amount of volatile organic.
Patent CA-2397267-A1 (CA)
Title: Fragments peptidiques et utilisations connexes comme antagonistes d'interferon de type 1
Inventor: TOVEY MICHAEL GERARD
IPC: C07K14/715
Filed: 2001-01-25
Abstract: La présente invention concerne des peptides qui sont constitués d'environ 9-12 acides aminés, présentent une séquence dérivant du site de liaison de l'interféron de la chaîne IFNAR1 du récepteur d'interféron de type 1 (type 1-IFN) et sont destinés à être utilisés en tant qu'antagonistes de type 1-IFN. La présente invention concerne notamment des peptides présentant la séquence FSSLKLNVY 9 mer (séquence ID no. 1) et des analogues de ceux-ci, qui sont destinés à être utilisés en tant qu'antagonistes de type 1-IFN. Selon cette invention, le peptide préféré est le peptide de séquence ID no. 1 et des analogues de celui-ci, la séquence ID no. 1 comprenant un reste asparagine supplémentaire (N) à la partie C-terminale et/ou un reste acide glutamique supplémentaire (E) à la partie N-terminale.
Patent CA-2397704-A1 (CA)
Inventor: TANGRI KULDIP CHAND
IPC: A61H35/02
Filed: 2001-01-22
Abstract: A handheld eye flushing apparatus comprises an eyecup (21).  Eyecup (21) holds eyewash liquid (20) in it for eye flushing. Eyecup (21) has a wider rim, contoured to the eye orbit and rests on the eye orbital area.  Further, this eyecup (21) has a stirring mechanism (22) inside of it to stir the eyewash liq-uid (20) during usage. The contents of the stirring mechanism (22) are attached to the eyecup (21).
Patent CA-2402553-A1 (CA)
Title: Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
Inventor: AHMADIAN HALEH
IPC: A61P9/10
Filed: 2001-03-09
Abstract: Methods for manufacture of citalopram through stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans are disclosed.
Patent CA-2403521-A1 (CA)
Title: Authentication in a packet data network
Inventor: HAVERINEN HENRY
IPC: G06F21/44
Filed: 2001-01-08
Abstract: Authentication method for authenticating a mobile node to a packet data network, in which a shared secret for both the mobile node and the packet data network is arranged by using a shared secret of the mobile node and a telecommunications network authentication centre. In the method, the mobile node sends its subscriber identity to the packet data network together with a replay attack protector. The packet data network obtains authentication triplets, forms a session key using them, and sends back to the mobile node challenges and a cryptographic authenticator made by using the session key. The mobile node can then form the rest of the authentication triplets using the challenges and then form the session key. With the session key, the mobile node can check the validity of the cryptographic authenticator. If the authenticator is correct, the mobile node sends a cryptographic response formed using the session key to the packet data network for authenticating itself to the packet data network.
Patent CA-2403999-A1 (CA)
Inventor: GUPTA BRIJ
IPC: B01J35/10
Filed: 2001-04-04
Abstract: L'invention concerne un procédé et un système à double réacteur destinés à l'hydrotraitement d'un flux de naphta catalytique de large coupe comprenant du naphta catalytique lourd (HCN) et du naphta catalytique intermédiaire (ICN). Par conséquent, une fraction HCN est hydrotraitée dans des conditions d'hydrotraitement non sélectives et une fraction ICN est hydrotraitée dans des conditions d'hydrotraitement sélectives. On peut amener les effluents de HCN et de ICN hydrotraités à des échangeurs thermiques afin de préchauffer la charge de ICN, rendant ainsi superflu l'utilisation d'un four.
Patent CA-2406966-A1 (CA)
Title: Photovoltaic modules with a thermoplastic hot-melt adhesive layer and a process for their production
Inventor: POST BERND
IPC: H01L31/048
Filed: 2002-10-08
Abstract: The invention relates to photovoltaic modules with a specific thermoplastic adhesive layer and the production thereof.
Patent CA-2410572-A1 (CA)
Inventor: MAHLING FRANK-OLAF
IPC: C08F210/02
Filed: 2001-05-25
Abstract: A method for polymerizing ethylene and optionally other monomers in a high-pressure reactor at pressures of 1000 - 4000 bars and temperatures of between 140 and 320 ~C at temperatures and pressures when the water behaves in a supercritical manner. According to the inventive method, water is introduced into the reactor in a continuous or intermittent manner.
Patent CA-2410981-A1 (CA)
Inventor: KALEKO MICHAEL
IPC: A61K35/76
Filed: 2001-06-01
Abstract: Cette invention se rapporte à des protéines de fibres adénovirales mutées et à des particules d'adénovirus contenant ces protéines, à des polynucléotides codant ces protéines et à des vecteurs contenant ces polynucléotides, ainsi qu'à des procédés de production et d'utilisation de ces particules adénovirales. Grâce à ces protéines de fibres mutées, les particules d'adénovirus ne se fixent plus à leur récepteur cellulaire naturel. Elles peuvent être alors reciblées sur un type de cellule spécifique grâce à l'addition d'un ligand au capside du virus, qui amène le virus à se fixer à une telle cellule et à l'infecter. On a établi la liste des mutations de fibres spécifiques qui suppriment la fixation au récepteur naturel. On a découvert que des particules d'adénovirus ayant certaines mutations de fibres augmentent le transfert génique et l'expression dans le foie par rapport à des particules virales ayant une fibre de type sauvage.
Patent CA-2411633-A1 (CA)
Inventor: QUIRING NEIL
IPC: B23K26/38
Filed: 2002-11-12
Abstract: An overhead conveyor system transports a selectable workpiece from vertically extending storage racks having a plurality of horizontally extending shelves with stationary stacks of workpieces to be processed on each shelf. Each shelf includes horizontally spaced shelf support members defining openings complementary to horizontally extending support members of a carriage. The horizontally extending members of the carriage are insertable between adjacent horizontally spaced shelf members to engage the upper most workpiece supported by the shelf located below the horizontally extending support members of the carriage. Workpiece engaging members operably associate or engage the upper-most workpiece with the carriage for movement vertically and horizontally along the path of travel to a workstation for processing.