baber/WOPTO huggingface dataset:
Patent AU-2020202181-A1 (AU)
Title: Naphthyridine compounds as jak kinase inhibitors
Inventor: HUDSON RYAN
IPC: C07D519/00
Filed: 2020-03-27
Abstract: 1:\Interwovn\NRPortbl\DCC\AAR\20024698_I.docx-27/03/2020 The invention provides compounds of formula (1): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of JAK kinases. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat inflammatory bowel diseases, and processes and intermediates useful for preparing such compounds.
Patent AU-2020207826-A1 (AU)
Title: System and method for secondary analysis of nucleotide sequencing data
Inventor: GARCIA FRANCISCO JOSE
IPC: G16B30/10
Filed: 2020-07-22
Abstract: SYSTEM AND METHOD FOR SECONDARY ANALYSIS OF NUCLEOTIDE 
SEQUENCING DATA 
ABSTRACT OF THE DISCLOSURE 
Disclosed herein are systems and methods for performing secondary analyses of nucleotide 
sequencing data in a time-efficient manner. Some embodiments include performing a secondary 
analysis iteratively while sequence reads are generated by a sequencing system. Secondary 
analyses can encompass both alignment of sequence reads to a reference sequence (e.g., the human 
reference genome sequence) and utilization of this alignment to detect differences between a sample 
and the reference. Secondary analysis can enable detection of genetic differences, variant detection 
and genotyping, identification of single nucleotide polymorphisms (SNPs), small insertions and 
deletion (indels) and structural changes in the DNA, such as copy number variants (CNVs) and 
chromosomal rearrangements.
WO 2018/068014 PCT/US2017/055653 
7/15 
600 
605 
Receive Imaging Data of a Sequencing Cyclef610 
Determine Bases and Quality Scores for Bases 
Determined 615 
620 
Perform Alignment 
Perform Variant Calling 630 
635 Yes 
End 
640 
FIG. 6
Patent AU-2020207953-A1 (AU)
Title: Bruton's tyrosine kinase inhibitors
Inventor: LIAO XIBIN
IPC: A61K31/4985
Filed: 2020-01-17
Abstract: Bruton's tyrosine kinase (BTK) inhibitors have the following Formula (I) or (II).
Patent AU-2020208371-A1 (AU)
Title: Substituted polycyclic carboxylic acids, analogues thereof, and methods using same
Inventor: CHEN SHUAI
IPC: A61K31/4375
Filed: 2020-01-15
Abstract: The present invention includes substituted polycyclic carboxylic acids, analogues thereof, and compositions comprising the same, which can be used to treat and/or prevent hepatitis B virus (HBV) infection and/or hepatitis D virus (HDV) in a patient. In certain embodiments, the invention provides a compound of formula (I), or a salt, solvate, geometric isomer, stereoisomer, tautomer, and any mixtures thereof.
Patent AU-2020208399-A1 (AU)
Title: Intravenous therapy selection system
Inventor: WILLYBIRO KATHRYN
IPC: G16H50/50
Filed: 2020-01-16
Abstract: An intravenous (IV) therapy selection system, may include a processor; a memory device to maintain an electronic medical record database comprising a plurality of medical records related to a plurality of patients; a clinician training module to provide training services and credentials to a plurality of clinicians; an IV therapy recommendation module to provide, via a display device, an IV device recommendation based on data descriptive of a first patient and a first clinician; and a placement location recommendation module to provide, via the display device, a recommendation on where to introduce the IV device into the first patient's body based on data descriptive of the first patient and the first clinician.
Patent AU-2020209221-A1 (AU)
Title: Confirmation of catheter placement within a vein
Inventor: MA YIPING
IPC: A61M25/00
Filed: 2020-01-16
Abstract: A catheter system may include a catheter adapter, which may include a distal end and a proximal end. The catheter system may include a catheter, which may include a distal end, a proximal end, a catheter lumen extending through the distal end of the catheter and the proximal end of the catheter, and an inner surface forming the catheter lumen. The catheter may extend distally from the distal end of the catheter adapter. The distal end of the catheter may include one or more holes. The distal end of the catheter may include one or more channels. The holes and/or the channels may facilitate visualization of blood flashback indicating the catheter is disposed within a vein of a patient.
Patent AU-2020245486-A1 (AU)
Title: Multispecific agents for treatment of cancer
Inventor: MCCAMISH MARK
IPC: C07K16/28
Filed: 2020-03-25
Abstract: The invention provides multispecific agents having one arm binding CD47, and a second arm binding to CD24. The invention also provides multispecific agents having one arm binding to SIRPa and a second arm binding to siglec-10.
Patent AU-2020265777-A1 (AU)
Title: Cheese and yogurt like compositions and related methods
Inventor: GIBSON MATT
IPC: A23J3/20
Filed: 2020-05-01
Abstract: Provided herein are cheese and yogurt compositions and the methods of making the same using one or more recombinant proteins.
Patent AU-2020266125-A1 (AU)
Title: Multivalent PD-L1 binding compounds for treating cancer
Inventor: BARRY MICHAEL A
IPC: C07K14/705
Filed: 2020-04-28
Abstract: This invention provides methods and materials for treating cancer. The invention encompasses methods and materials for delivering programmed death-ligand 1 (PD-L1) binding compounds and/or compositions containing one or more monovalent or multivalent programmed death-ligand 1 (PD-L1) binding compounds which are administered to a mammal having cancer to treat the mammal. In some cases, a multivalent PD-L1 binding compound can include two or more programmed cell death protein 1 (PD-1) polypeptides (and/or fragments thereof having the ability to bind PD-L1). This invention also provides methods and materials for making multivalent PD-L1 binding compounds and methods and materials for making nucleic acid molecules that encode PD-L1 binding compounds.
Patent AU-2020267266-A1 (AU)
Title: ICT asset risk management system
Inventor: VAN LOGGERENBERG ANTON
IPC: G06Q10/06
Filed: 2020-11-12
Abstract: The invention relates to a system and method of monitoring the security compliance of a system 
of ICT assets based on a security posture characterisation. The method includes a data 
structure linking ICT assets, an ICT asset type characterisation, one or more ICT threats linked 
to the asset type characterisation, and one or more ICT security controls linked to the CT 
threats. In some implementations, the data structure further includes further data operable for 
determination of a probability of a security threat occurring, and identification of one or more 
security controls for implementation on one more linked assets to improve the security posture.  
1
600 
Start 
Define a data structure comprising a plurality of discrete 
compliable assets grouped according to one or more 
common ICT threats (Asset Type) 
601 
For each Asset Type, assign one or more ICT threat control 
actions controls operable to mitigate the one or more common 
ICT vulnerabilities; 
602 
Determine at least one asset is below a compliance threshold; 
603 
When a determined system compliance is below a threshold 
compliance level, determine a compliance plan based on 
implementation of the one or more ICT threat control actions 
mapped to the Asset Type in the data structure 604 
Execute the compliance plan 
605 
Figure 14
Patent AU-2020286513-A1 (AU)
Title: Systems, devices, and methods for treating heart valves
Inventor: PATEL DARSHIN S
IPC: A61F2/24
Filed: 2020-06-08
Abstract: Systems, assemblies, and methods for treating valve regurgitation and other valve problems are described. Prosthetic valves can have integrated coverings or flanges. Prosthetic valves can have a flange attached to the inflow end of the annular frame and designed to extend outwardly therefrom. Docking devices can be used to repair or reshape native heart valves and to secure prosthetic heart valves at a specific location and position relative to a native heart valve. Delivery systems can be used to deploy a docking device into the heart, including a lubricous sleeve in the delivery system. Packaging and storage systems suitable for the delivery systems are described.
Patent AU-2020299967-A1 (AU)
Title: A damage detection apparatus and method
Inventor: POPOV IVAYLO
IPC: G06Q10/00
Filed: 2020-06-30
Abstract: The present invention provides an apparatus and method to automatically detect vehicle damage which minimises the time taken to detect damage per vehicle. Preferably, the action of damage detection is also performed with an action of causing the fixing of any detected damage, where appropriate. To this end, the present invention provides a damage detection unit arranged to detect damage on a vehicle. The damage detection unit comprises a receiving unit arranged to receive an image from a camera and a determining unit arranged to determine damage on the vehicle based on the received image. Moreover, the damage detection unit further comprises a storing unit arranged to store information about damage previously determined to be present on the vehicle and a comparing unit arranged to compare the damage determined by the determining unit with the information about previous damage as stored by the storing unit.
Patent AU-2020316330-A1 (AU)
Title: Methods and products for treatment of gastrointestinal disorders
Inventor: SMITH MARK
IPC: A61K35/74
Filed: 2020-07-17
Abstract: Described herein are compositions and methods for the delivery of microbial therapeutics useful for the treatment of disorders related to intestinal dysbiosis. In various aspects, the present invention provides compositions and methods that are useful treating or preventing inflammatory bowel disease (IBD) in a subject in need thereof. For instance, the present invention, in part, relates to a plurality of bacterial isolates, wherein at least two of the plurality of bacterial isolates are isolated from a stool of different human donors.
Patent AU-2020320527-A1 (AU)
Title: Freezing apparatus
Inventor: HAMADATE JUNICHI
IPC: F25B41/00
Filed: 2020-06-05
Abstract: A freezing apparatus A, B comprises: a casing 2a accommodating a compressor 4 therein; a four-way valve 16; an accumulator 11; first piping 21 through which refrigerant flows between the four-way valve 16 and a discharge part 4b of the compressor 4; and second piping 22 through which refrigerant flows between the four-way valve 16 and the accumulator 11. The four-way valve 16, the first piping 21, and the second piping 22 are made of stainless steel.
Patent AU-2020328611-A1 (AU)
Title: Extracellular vesicle-aso constructs targeting STAT6
Inventor: BURZYN DALIA
IPC: A61K31/7125
Filed: 2020-08-14
Abstract: The present disclosure relates to extracellular vesicles, e.g., exosomes, comprising an antisense oligonucleotide (ASO), wherein the ASO comprises a contiguous nucleotide sequence of 10 to 30 nucleotides in length that is complementary to a nucleic acid sequence within a STAT6 transcript. Also provided herein are methods for producing the exosomes and methods for using the exosomes to treat and/or prevent diseases or disorders.
Patent AU-2020340242-A1 (AU)
Title: Recirculating water system composition
Inventor: SAYRE CURTIS
IPC: C02F1/76
Filed: 2020-08-18
Abstract: Disclosed herein is a composition for the treatment of a recirculating water system, comprising: trichloro-s-triazentrione (TCCA) in an amount of from about 75% to about 98% by mass of the composition; an inorganic salt present in an amount of from about 2% to about 25% by mass of the composition; and an auxiliary agent in a total amount of from about 0% to about 10% by mass of the composition. Also disclosed herein is a formed object comprising the composition, a process for preparing the formed object, and a method of using the formed object.
Patent AU-2020345801-A1 (AU)
Title: Devices and methods for modulating ADMA in blood
Inventor: SINGH JAIPAL
IPC: A61K38/00
Filed: 2020-09-10
Abstract: Compositions and methods are provided for metabolically degrading ADMA. In one embodiment a device is provided for reducing a patient's ADMA levels in their blood wherein the device comprises a biologically active dimethylarginine dimethylaminohydrolase (DDAH) polypeptide covalently linked to a solid support. In one embodiment a method for reducing ADMA levels in a patient's blood comprises the step of contacting the patient's blood or a blood fraction with an immobilized biologically active DDAH polypeptide, wherein contact of the patient's blood with said DDAH polypeptide results in degradation of ADMA present in the patient's blood.
Patent AU-2020389348-A1 (AU)
Title: Non-viral transcription activation domains and methods and uses related thereto
Inventor: MOJZITA DOMINIK
IPC: C12N15/82
Filed: 2020-11-18
Abstract: The present invention relates to the fields of life sciences, genetics and regulation of gene expression. Specifically, the invention relates to a non-viral transcription activation domain for a eukaryotic host. Also, the present invention relates to a polypeptide or artificial transcription factor comprising the transcription activation domain of the present invention. And furthermore, the present invention relates to a polynucleotide, an expression cassette, expression system, and/or a eukaryotic host. Still, the present invention relates to a method for producing a desired protein product in the eukaryotic host of the present invention or to a method of preparing a non-viral transcription activation domain of the present invention or a polynucleotide encoding said non-viral transcription activation domain. And still further, the present invention relates to use of the transcription activation domain, polypeptide, artificial transcription factor, polynucleotide, expression cassette, expression system or eukaryotic host of the present invention for metabolic engineering and/or production of a desired protein product.
Patent AU-2020402369-A1 (AU)
Title: Stable anti-PD-1 antibody pharmaceutical preparation
Inventor: JUNG YOUNG SEOK
IPC: C07K16/28
Filed: 2020-12-14
Abstract: The present invention relates to a stable anti-PD-1 antibody pharmaceutical preparation free of a buffer, and to a method for preparing same, the pharmaceutical preparation comprising: an anti-PD-1 antibody or an antigen-binding fragment thereof; and a stabilizing agent.
Patent AU-2020414359-A1 (AU)
Title: Steganographic image encoding of biometric template information on a card
Inventor: OSBORN KEVIN
IPC: G06F21/36
Filed: 2020-11-24
Abstract: Various embodiments are generally directed to utilizing a steganographically encoded image with an offline and/or online verification or authentication protocol. A method for using the steganographic image can include: receiving or utilizing a steganographic image associated with a user at a third-party device, the steganographically encoded image including an identification of a user steganographically encoded with a fingerprint template of the user, and authenticating the user using the steganographically encoded image.
Patent AU-2020417839-A1 (AU)
Title: Compact reconfigurable integrated laser-phaco systems and methods of use
Inventor: MCWHIRTER JOHN
IPC: A61F9/007
Filed: 2021-01-01
Abstract: A fully integrated laser-ultrasound, including femto-phaco, system having a foot print of less than 1,500 sq inches. Integrated communication and control system for laser-ultrasound, including femto-phaco, system including common control system and GUI. A reconfigurable laser- ultrasound, including femto-phaco, femto-phaco system having different configurations and positions of a laser delivery head, and having a single laser beam path length for all configurations. Integrated systems and methods for performing laser and phacoemulsification operations. A reconfigurable system for performing a laser procedure in a laser configuration, and then being reconfigured into a phaco configuration, to perform a phacoemulsification, and then being reconfigured back to the laser configuration.
Patent AU-2020419451-A1 (AU)
Title: Hydrofoil for small vessels
Inventor: VALERA RUIZ DE LA SIERRA FRANCISCO JAVIER
IPC: B63B1/24
Filed: 2020-01-02
Abstract: The invention relates to a hydrofoil for small vessels (1), comprising a front foil set (3) formed by a wing (32), with marked negative dihedral, which is attached to the vessel (1) by means of two struts (31), of circular or quasi-circular section, and a rear foil set (2) formed by a wing (22) that is flat or with minimal dihedral, attached to the vessel (1) by means of two struts (21); the front (3) and rear (2) foil sets being positioned longitudinally forward and aft, respectively, of the overall centre of gravity of the vessel, including also the pilot and/or crew.
Patent AU-2020427921-A1 (AU)
Title: Automated generation of explainable machine learning
Inventor: BAVLY NITZAN
IPC: G06F16/20
Filed: 2020-07-01
Abstract: OF THE DISCLOSURE 
A computer-implemented method and system are provided to perform a 
machine learning pipeline process to produce an explainable machine learning 
model. A computing device may be configured to train a plurality of machine learning 
models with a set of respective feature datasets to generate an accuracy and 
explainability property for each trained model. The computing device may evaluate a 
plurality of the trained machine learning models and select a model as an 
explainable machine learning model based on at least one of the accuracy and the 
explainability property.  
23 
EAST\175007616.1
Patent WO-2021155432-A1 (WO)
Title: Chemical treatment for preparing metal electrodes
Inventor: BEST ADAM
IPC: H01M10/058
Filed: 2021-02-03
Abstract: The present disclosure relates to chemical treatments for preparing metal electrodes, including  ex-situ  chemical treatments for preparing metal electrodes and to  ex-situ  chemically treated metal electrodes, which can be used in electrochemical cells. The present disclosure also relates to methods for forming a metal fluoride-based layer (e.g. a SEI fluoride layer) on a metal or an electrode thereof comprising an  ex-situ  chemical treatment of the metal or electrode thereof, and to electrochemical cells comprising the  ex-situ  chemically treated metal electrodes.
Patent WO-2021258129-A1 (WO)
Title: Mouthguard
Inventor: NGUYEN HOANG
IPC: A61C7/08
Filed: 2021-06-16
Abstract: A mouthguard for protecting a wearer's teeth from bruxism, the mouthguard comprising: (a) a cavity configured to receive at least a portion of a first row of teeth of the wearer; (b) a guide extending towards the wearer's second row of teeth, the guide being configured to guide the jaw of the second row of teeth such that in use, when the wearer brings their teeth together, front teeth of the opposed jaws are brought substantially into alignment with one another; and (c) a bite region at a base of the guide configured, in use, to abut the front teeth of the second row of teeth when the wearer brings their teeth together.
Patent AU-2021200870-A1 (AU)
Title: Beverage capsule, associated filling method, capsule filling apparatus and beverage
Inventor: TITZ PETER
IPC: A47J31/06
Filed: 2021-02-11
Abstract: Disclosed is a capsule for the preparation of a beverage in a beverage machine by 
feeding liquid into the capsule and extracting a beverage out of the capsule. The capsule 
5 comprises containment walls forming an interior cavity containing a beverage precursor 
for mixing with the liquid in the cavity, wherein the beverage precursor comprises a layer 
of compressed coffee precursor and a layer comprising a further substance, wherein the 
layer of compressed coffee precursor is more compressed than the layer comprising the 
further substance. Also disclosed is a capsule for the preparation of a beverage in a 
0 beverage machine by feeding liquid into the capsule and extracting a beverage out of the 
capsule through an outlet side of the capsule, wherein the capsule comprises 
containment walls forming an interior cavity containing a beverage precursor for mixing 
with the liquid in the cavity, wherein the beverage precursor comprises a layer of coffee 
precursor and a layer comprising a further substance comprising an algae product, 
5 wherein the layer comprising the further substance is located between the layer of coffee 
precursor and the outlet side. Also disclosed is a corresponding method of filling a 
capsule, a beverage obtained from a capsule and a capsule filling apparatus.  
(Fig. 1) 
17393822_1 (GHMatters) P115532.AU
1/2 
2a 314 13 14 
2b la" 
77 -' ~ 2c.\, 7 
5 2c 12 
10 2b 
_____________ 6 2a 
2d Fig1 Fig. 2 
15 9 9b 
9a 
_a 5/ 
Fig. 3 Fig4
Patent AU-2021200910-A1 (AU)
Title: Pandemic protocol for emergency dispatch
Inventor: CLAWSON JEFFREY
IPC: G06Q50/22
Filed: 2021-02-12
Abstract: Systems and methods are provided to guide an emergency dispatcher in 
responding to emergency calls involving a patient manifesting symptoms of a 
pandemic illness. The systems and methods may include an emergency dispatch 
protocol configured to facilitate uniform and consistent gathering of information 
concerning the emergency situation. The emergency medical dispatch protocol may 
include one or more dispatch protocols configured for particular emergency situations, 
such as to aid the dispatcher in processing calls relating to a pandemic illness (e.g., 
severe respiratory infection like influenza). The emergency dispatch protocol may 
present a pre-scripted interrogation, including preprogrammed inquiries for a 
dispatcher to ask the caller. The pre-scripted interrogation of the dispatch protocol 
facilitates uniform and consistent gathering of symptom information relating to a 
pandemic outbreak. The information may be received and stored and/or processed to 
determine a determinant value corresponding to an appropriate emergency dispatch 
response.  
17387656_1 (GHMatters) P99088.AU.2
1/14 
100 
Patient Dispatch Center 102 
117 Dispatcher 
Computer 106 
Memory 107 
Emergency Medical 
Dispatch Protocol 1_08 
Dispatch output 130 
Prtoos 2 Device 
Pandemic 
Caller Protocol 126 Input 128 
118 Device 
Determinant Value 
Calculator 110 CAD System 
Reporting Module L114 112 
Diagnostic Tools 120 
Pandemic 
DiagnosticTool 122 Telephone 
Equipment 
116 
FIG. 1
Patent AU-2021201501-A1 (AU)
Title: Lng production with nitrogen removal
Inventor: VOVARD SYLVAIN
IPC: F25J1/02
Filed: 2021-03-10
Abstract: A method and system for liquefying a natural gas feed stream and removing nitrogen 
therefrom.
2/5 
FIGURE 2 
22 
21 
2 2_ _-_-_ _--_ _---
20 
221d 
12 
20524 
Fee d--- ---- > ------
Patent AU-2021203391-A1 (AU)
Title: Reversing mechanism for a power tool
Inventor: BOTHMANN RICHARD
IPC: B25F5/00
Filed: 2021-05-25
Abstract: A reversing mechanism for a pneumatically or hydraulically powered tool having a 
rotor adapted to selectively rotate in either one of first and second rotational directions. The 
reversing mechanism allows a user to actuate a button that rotates a valve to direct air flow 
5 through the tool. By pressing the button, the button will move a base laterally, and in doing 
so, rotates the valve. Rotating the valve distributes fluid to cause the rotor to rotate in a 
selected rotational direction.  
17719078_1 (GHMatters) P116366.AU
1/7 
100 
12 
101 
F4 
106 
108 
109 
FIG. 1