baber/WOPTO huggingface dataset:
Patent JP-2000508002-A (JP)
Title: ヒドロキノンを含有するサーモトロピック液晶ポリマーを製造するための改良法
IPC: C08G69/44
Filed: 1997-02-05
Abstract: (57)【要約】
４−ヒドロキシ安息香酸、２，６−ナフタレンジカルボン酸、テレフタル酸、ヒドロキノン、およびＮ−アセチル−４−アミノフェノールから、これらのモノマーを無水酢酸の存在下に加熱することにより製造される液晶ポリマーは、コモノマーとしてイソフタル酸をも約０．５〜約１０モル％の量で含有させると、より容易に高分子量で合成される。
Patent JP-2000507324-A (JP)
IPC: F04F5/54
Filed: 1997-03-07
Abstract: PCT No. PCT/SE97/00393 Sec. 371 Date Sep. 22, 1998 Sec. 102(e) Date Sep. 22, 1998 PCT Filed Mar. 7, 1997 PCT Pub. No. WO97/36044 PCT Pub. Date Oct. 2, 1997Methods and apparatus are disclosed for degassing gas-containing fluid media in a container with the apparatus including a centrifugal pump for pumping the gas-containing fluid medium from the container, an ejector including a suction side, an ejector inlet for a drive fluid, and an ejector outlet for the drive fluid, whereby at least a portion of the pump fluid medium is fed to the suction side of the ejector for removing the gas therefrom, a diversion conduit for diverting a separate portion of the pump fluid medium from the centrifugal pump to the ejector inlet, and a return conduit for returning the separate portion of the fluid medium from the ejector outlet to the container.
Patent JP-2000508845-A (JP)
Title: ビデオ画像シーケンスの新たなサウンドトラックに対する自動同期
IPC: G11B27/10
Filed: 1997-03-25
Abstract: (57)【要約】
既存のビデオの新たなサウンドトラックへの同期を、元のサウンドトラックおよび新たなサウンドトラックの音素分析を通じて達成する。音素のような個々の音を、元のビデオ記録に対するサウンドトラック内で識別し、それに対応する画像を格納する。同様に、新たなサウンドトラックも分析し、個々の音を識別する。これらを用いて、格納されている画像を選択し、新たなビデオ・シーケンスを作成する。次に、画像のシーケンスを互いに円滑に調和させてビデオ・ストリームを形成し、新たなサウンドトラックに同期させる。この手法は、所与のビデオ・シーケンスをいずれの任意のオーディオ・トラックとも同期させることができる。更に、ビデオ画像の新たな音に対する一致は、高度に自動化して実行することができ、これによって、必要な手作業の手間を減少させる。
Patent JP-2001512452-A (JP)
IPC: A61K45/06
Filed: 1998-02-14
Abstract: Composition for the treatment of infant or adult respiratory distress syndrome (IRDS and ARDS) contains N-(3,5-dichloropyrid-4-yl)-3- cyclopropylmethoxy-4- difluoromethoxybenzamide (II) (and/or its salts) and a lung surfactant.
Patent JP-2001511950-A (JP)
Title: ＢｅＴｅバッファ層を有する▲ＩＩ▼−▲ＶＩ▼族半導体デバイス
IPC: H01S5/347
Filed: 1998-02-10
Abstract: (57)【要約】
ＩＩ−ＶＩ族半導体デバイスは、上端部の電気コンタクトに電気的に接続された積重ね状のＩＩ−ＶＩ族半導体層を含む。この積重ね状ＩＩ−ＶＩ族半導体層を支持し、前記電気コンタクトの反対側に位置決めされたＧａＡｓ基板が設けられている。ＧａＡｓ基板と積重ね状ＩＩ−ＶＩ族半導体層との間にはＢｅＴｅバッファ層が設けられている。ＢｅＴｅバッファ層により、ＧａＡｓ基板と積重ね状ＩＩ−ＶＩ族半導体層との間のインターフェースにおける積層欠陥を低減することができる。
Patent JP-H11506444-A (JP)
IPC: A01N63/00
Filed: 1996-05-09
Abstract: Methods and compositions are disclosed for producing air-activated, i.e., oxygen (O2) activated, disinfectant-sterilent solutions. Solutions containing a haloperoxidase (i.e., a halide:hydrogen peroxide (H2O2) oxidoreductase, such as myeloperoxidase, eosinophil peroxidase or lactoperoxidase) plus a halide or combination of halides (i.e., chloride, bromide and/or iodide), an oxidase (i.e., a substrate:O2 oxidoreductase) capable of generating H2O2, and a substrate specific for that oxidase, are separately prepared under aerobic conditions, but all of the component solutions are made anaerobic prior to final combination and mixing. The anaerobic formulations are dispensed into containers capable of maintaining the anaerobic condition (e.g., pressurized canisters). Dispensing the solution at the time of use exposes the formulation to air (i.e., O2) which activates its disinfectant-sterilent properties. O2 is the rate limiting component for oxidase generation of H2O2. Under aerobic conditions the oxidase catalyzes the oxidation of its substrate and the reduction of O2 to generate H2O2. In turn, H2O2 serves as substrate for haloperoxidase which catalyzes the oxidation of halide to hypohalous acid. Hypohalous acid reacts with an additional H2O2 to generate singlet molecular oxygen (1O2). Hypohalous acid (e.g., hypochlorous acid) and especially 1O2 are potent microbicidal agents. Both haloperoxidase generation of hypohalous acid and its reactive consumption to yield 1O2 are dependent on the availability of H2O2. A high rate of H2O2 generation does not result in the accumulation of hypohalous acid, but instead results in a high rate of 1O2 production. The microbicidal capacity and toxicity of 1O2 are limited by the half-life of this metastable electronically excited reactant, and as such, disinfectant-sterilent activity is temporally defined by and confined to the dynamics of oxidant generation. The disinfectant-sterilent activity of formulation requires air exposure and is dependent on the presence of the halide-haloperoxidase combination employed, the activity of the oxidase present, the availability of oxidase-specific substrate and the availability of O2.
Patent JP-2000513200-A (JP)
Title: フライホイール・エネルギアキュムレータ
IPC: H02K7/09
Filed: 1998-02-14
Abstract: (57)【要約】
フライホイール・エネルギアキュムレータであって、鉛直な軸、及び該軸に取り付けられた超伝導性の磁気式の受動的なアキシャル支承部（ＳＭＬ）、並びにインナーロータ形電気モーター／発電機を備えており、インナーロータ形電気モーター／発電機のロータが機械的に複数のフライホイールに連結されており、インナーロータ形電気モーター／発電機のステータがエネルギアキュムレータの真空ケーシングに対して位置固定されている。フライホイール・エネルギアキュムレータの装置全体が、上下に組み立てられて互いに結合された個別のモジュール、電気機械のステータ、ロータ及びケーシングリングを備えた中央のモーター／発電機・モジュール（Ａ）、中央のモジュールの上側及び下側に配置された複数のフライホイール・モジュール（Ｂ）、並びに該フライホイール・モジュール自体とモーター／発電機・モジュール（Ａ）との間に配置されたＳＭＬ・支承モジュール（Ｃ）から成っている。ＳＭＬ・支承モジュール（Ｃ）の個別のＳＭＬの総数がフライホイール・モジュール（Ｂ）の数の二倍であり、この場合、各フライホイールが上側及び下側のそれぞれ１つのＳＭＬを有しており、個別のＳＭＬ・支承モジュール（Ｃ）がそれぞれ１つ若しくは２つのＳＭＬを有している。ＳＭＬ・支承モジュール（Ｃ）の数がフライホイールモジュール（Ｂ）の数よりも二倍大きくなっている。
Patent JP-2001516304-A (JP)
Title: リムとディスク一体型ホイールとの連結構造及び方法
IPC: B60B3/04
Filed: 1998-03-18
Abstract: (57)【要約】
溶接材の流入を容易にするための傾斜面を有して溝（２８）が形成された独特の一体型ホイールが開示されている。リム（２４）が溝（２８）内に延びており、リム（２４）は、溝の面と関連して作用して適切な位置決めおよび確実な連結を提供する。さらに、ディスク（２２）を形成する方法が開示されている。
Patent JP-2002505663-A (JP)
Title: アリールホウ酸エステル
IPC: C07B61/00
Filed: 1998-04-09
Abstract: (57)【要約】
本発明は、VIII族金属触媒及び適当な塩基の存在下、カップリング位置にハロゲン置換基又はハロゲン様置換基を有する芳香環化合物を、二ホウ素誘導体と反応させることを含む、有機化合物を共有結合でカップリングする方法を提供する。本発明はまた有用なアリールホウ素中間体も提供する。
Patent JP-2001518841-A (JP)
IPC: B02C15/00
Filed: 1997-04-15
Abstract: PCT No. PCT/FR97/00682 Sec. 371 Date Nov. 2, 1999 Sec. 102(e) Date Nov. 2, 1999 PCT Filed Apr. 15, 1997 PCT Pub. No. WO98/46357 PCT Pub. Date Oct. 22, 1998A grinder having an annular track with a horizontal axis (14), a roller (16) capable of travelling over the track, a mechanism for pressing the roller against the track and means (18) for displacing the material from one edge of the track to the other in such a way that it passes several times beneath the roller before being evacuated. To enhance the efficiency of the grinder and the distribution of mechanical stresses in the roller and the track, the track (14) and the roller (16) are designed in such a way that the gap between them decreases from the edge of the track (14) located on the side for supplying the material to be ground to a distance from this edge at least equal to 80% of the width of the track, and in that this interval then swiftly increases to form a decompression area (19) on the ground material evacuation side.
Patent JP-2001525705-A (JP)
Title: 人工腸管
IPC: A61F2/04
Filed: 1998-05-13
Abstract: (57)【要約】
本発明は人工腸管に関し、本発明による人工腸管（１００）は、哺乳動物の腸管を典型的に裏打ちしている１種または２種以上の複数種の生物学的成分（２０５）の層により裏打ちされている内側表面（２１５）を有する第一中空繊維（２０３）を備えている。さらにまた、第二中空繊維（２０１）が、この第一中空繊維と隣接している。１種または２種以上の複数種の生物学的成分の層は本質的に、腸細胞からなる。この腸細胞により裏打ちされた内側表面に、栄養物質を含有する補給溶液を潅流させ、これらの栄養物質を第一中空繊維の壁部を横切って輸送する。その結果として、栄養物質は第二中空繊維中に拡散される。培養培地、血液および血漿からなる群から選択される潅流溶液を、第二中空繊維の内側表面に潅流させることができ、これによりこの潅流溶液は栄養物質により栄養付与される。
Patent MX-158519-A (MX)
Inventor: PARGAMIN LAURENT
IPC: C03C21/00
Filed: 1982-10-28
Abstract: A tempered glass dielectric material for use as an electrical insulator is thermally tempered to produce surface compression between 200 MPa and 400 MPa. At least part of the material is then chemically tempered under conditions of temperature and duration such that the surface compression due to the thermal tempering is reduced by between 50% and 80%. The chemical tempering is effected by applying to the relevant part of the material, at ambient temperature, a solution containing alkaline salts. This solution is dried and the material then heated for several hours at a temperature between 300 DEG  C. and 500 DEG  C. The solution has the following composition (in percentage by weight): -H2O 70% to 90%  -Starch 2% to 10% -KNO3 4% to 12% - K2HPO4 + KCl + K2SO4 4% to 20% -
Patent MX-159103-A (MX)
Inventor: SCHAUPP RICHARD E
IPC: F02M37/32
Filed: 1984-04-06
Abstract: A filter assembly characterized by an electric heater assembly having a heater coil disposed in an inlet flow path to filter media and carried within the filter media. The electric heater assembly also includes a thermostat with the inlet portion of the flow path for sensing fuel temperature immediately prior to passing into the filter media.
Patent MX-162500-A (MX)
Inventor: ULRICH LAWRENCE W
IPC: B31B5/80
Filed: 1985-03-12
Abstract: A carton erector apparatus for setting up folding carton blanks and unfolding their bottom flaps. The apparatus includes a carton blank storage section, a carton blank set-up section and a bottom flap folding section. The carton blank storage section includes a magazine assembly for storing and urging knocked-down carton blanks towards the carton set-up section. The carton set-up section includes a carton opening assembly mounted on a substantially horizontal carriage plate movable in a direction transverse to the direction of movement of the carton blanks in the magazine assembly. A pivot arm assembly is pivotally secured to the folding arm assembly and is movable between first and second position respectively parallel and perpendicular to the folding arm assembly. A grasping means is secured to the pivot arm assembly to grasp the side panel of the forward carton in the magazine assembly when the pivot arm assembly and the folding arm assembly into their second positions is effective to set-up the carton blank into a tubular form. Bottom flap folding means are provided to infold the bottom flaps of the set-up carton.
Patent NZ-204912-A (NZ)
Title: Imidazobenzodiazepine derivatives,methods for their preparation and pharmaceutical compositions which contain them
Inventor: HUNKELER W
IPC: C07D487/14
Filed: 1983-07-15
Abstract: There are described novel pharmaceutically active substances which have a pronounced affinity to the central benzodiazepine receptors and which have only a low toxicity. These active substances, namely imidazobenzodiazepines of the formula    <IMAGE>  I  wherein A is lower alkylene, n is zero or 1, R1 is lower alkynyl, lower alkenyl, aryl, (C3-8)-cycloalkyl optionally substituted by lower alkyl or (C5-8)-cycloalkenyl optionally substituted by lower alkyl, or a 5- or 6-membered saturated or unsaturated heterocycle which contains an oxygen or sulphur atom as a ring member and which is optionally substituted by lower alkyl, R4 and R5 each are hydrogen, halogen, trifluoromethyl, cyano, nitro, amino or lower alkyl and either R2 is hydrogen and R3 is lower alkyl or R2 and R3 together are dimethylene, trimethylene or propenylene, the compounds of formula I in which R2 and R3 together are dimethylene, trimethylene or propenylene having the (S) or (R,S) configuration with reference to the carbon atom denoted by  gamma , and their pharmaceutically acceptable acid addition salts, can be used as medicaments in the form of pharmaceutical preparations, especially in the control of convulsions and anxiety states and/or in the partial or complete antagonization of some or all activities which 1,4-benzodiazepines having tranquillizing activity or other substances display via the central benzodiazepine receptors.
Patent NZ-215605-A (NZ)
Title: Preparation of a dna sequence
Inventor: MULLIS K B
IPC: C12Q1/68
Filed: 1986-03-26
Abstract: The present invention provides a process for detecting the presence or absence of at least one specific nucleic acid sequence in a sample or distinguishing between two different nucleic acid sequences in said sample, wherein each nucleic acid sequence to be detected consists of two separate strands, which process comprises amplifying the specific sequence or sequences (if present) by   (a) treating the sample with one oligonucleotide primer for each of the two strands of each different specific nucleic acid sequence being detected under hybridizing conditions such that for each strand of each different sequence being detected an extension product of each primer is synthesized which is complementary to each nucleic acid strand, wherein said primers are selected so as to be substantially complementary to each strand of each specific sequence such that the extension product synthesized from one primer, when it is separated from its complement, serves as a template for synthesis of an extension product of the other primer; (b) treating the product of step (a) under denaturing conditions to separate the primer extension products from their templates; (c) treating the product of step (b) with oligonucleotide primers such that a primer extension product is synthesized using each of the single strands produced in step (b) as a template; and detecting the thus amplified sequence or sequences (if present).
Patent NZ-218865-A (NZ)
Title: Preparing samples for detecting of specific dna sequences
Inventor: SNINSKY J J
IPC: C12Q1/68
Filed: 1987-01-08
Abstract: The presence or absence of a nucleic acid sequence associated with one or more related viruses in a sample containing one or more nucleic acids and suspected of containing such sequence can be detected by amplifying the sequence using primers to form extension products as templates and detecting the amplified product if it is present. This may be accomplished by adding a labeled hybridization probe to the amplified product either free in solution or after immobilization on a solid support. Preferably the virus constitutes AIDs viruses and heapdnaviruses.
Patent NZ-220324-A (NZ)
Title: A method for cryopreserving a biological sample and substrates for use in the method
Inventor: MORRIS GEORGE JOHN
IPC: A01N1/02
Filed: 1987-05-15
Abstract: Biological samples, especially mammalian cells, can be frozen, stored and thawed with increased percentage viability by freezing in an aqueous medium in the presence specifically of organic solids, desirably cholesterol, which cause nucleation at or near the freezing point of the medium thereby diminishing damage. The medium desirably also contains a cryoprotectant eg DMSO or glycerol.
Patent NZ-224568-A (NZ)
Title: Treating matter in at least two annular beds
Inventor: DODSON CHRISTOPHER EDWARD
IPC: B01J8/08
Filed: 1988-05-10
Abstract: Matter to be treated is passed through at least two treating regions 12, 14 sequentially. In each region a bed 29, 31 of the matter is moved in a band continuously along an annular path by passing fluid through the bed along the path. The annular paths of the regions 12, 14 are concentric.
Patent NZ-232467-A (NZ)
Title: Stable aqueous dispersion containing at least 20% by weight of solids, suitable for use as a coating colour composition
Inventor: NGUYEN CHARLES C
IPC: C09D151/02
Filed: 1990-02-09
Abstract: A stable aqueous polymeric dispersion comprising a graft copolymer of thinned, gelatinized starch and one or more vinyl grafting monomers, the vinyl monomers including at least 10% by weight 1,3-butadiene is disclosed. Also disclosed are paper coating color compositions comprising the polymeric dispersions and pigments and improved high gloss papers coated with the coating color compositions.
Patent NZ-238749-A (NZ)
Title: Aerosol inhalation drug formulations with 1,1,1,2-tetrafluoroethane as propellant and a perfluorinated surfactant
Inventor: JOHNSON KEITH ARTHUR
IPC: A61K47/20
Filed: 1991-06-27
Abstract: Aerosol formulations comprising an inhalation drug, 1,1,1,2-tetrafluoroethane (P134a) and a surface active agent soluble in 1,1,1,2-tetrafluoroethane.
Patent NZ-240441-A (NZ)
Title: Thiazol- or thiadiazol-substituted 7-acyl-3-substituted carbamoyloxy cephem derivatives and antibacterial compositions thereof; cephem intermediates
Inventor: SHIGETO NEGI
IPC: C07D501/26
Filed: 1991-11-01
Abstract: A compound represented by the following formula (1a): a process for the preparation thereof, an antibacterial composition comprising the same and the use thereof for the preparation of a medicament and for the synthesis of related cephem compounds.
Patent NZ-270926-A (NZ)
Title: Bending glass sheet using a ring mould
Inventor: WOODWARD ALAN CHARLES
IPC: C03B23/03
Filed: 1995-04-12
Abstract: During the bending of glass sheets by certain methods, e.g. press bending, a heat-softened glass sheet (11) is transferred from conveyor means (58,59) to a ring mould (62). Such transfer is preferably achieved without adversely affecting the optical quality of the sheet. A method and apparatus for bending are described wherein transferring the sheet (11) is effected by lowering part of the conveyor means (58,59) from an upper position to a lower position below the upper surface of the ring mould, and wherein bending the sheet comprises the step of raising both the ring mould (62) and the conveyor means (58,59). <IMAGE>
Patent NZ-272199-A (NZ)
Title: 1,9-bridged thiazolo[3,2-a]quinoline derivatives and medicaments
Inventor: JAETSCH THOMAS
IPC: C07D513/16
Filed: 1995-05-24
Abstract: 1,9-Bridged thiazoloÄ3,2-aÜquinoline derivs. (I) and their hydrates, addn. salts and alkali, alkaline earth, silver and guanidinium salts are new; X = 1-3C alkyl or cyclopropyl; Z = gp. of formula (a)-(c): R1 = H, 1-4C alkyl opt. substd. by OH, OMe, NH2, NHMe or NMe2; or (5-methyl-2-oxo-1,3-dioxol-4-yl)-methyl; R2 = H, Me, -CH=CH-COOR2', -CH2-CH2-COOR2', -CH2-CO-Me or -CH2-CH2-CN; R2' = Me or Et; R3, R6, R8 = H or Me; R4 = H, OH, NR7R8, -CH2OH, -CH2-NR7R8, COOH, COOMe or COOEt; R5 = H, 1-3C alkyl or cyclopropyl; R7 = H, 1-3C alkyl opt. substd. by OH, 1-4C alkoxycarbonyl or 1-3C acyl; B = CH2, O or a direct bond.
Patent NZ-298981-A (NZ)
Title: Preparation of spray dried erythropoietin
Inventor: MEHTA DEEPAK B
IPC: A61K38/22
Filed: 1995-12-15
Abstract: Disclosed is a method for preparing stable, spray dried rhEPO comprising A) providing an aqueous solution of rhEPO having a concentration within the range of about 20mg/ml to about 100mg/ml; b) atomizing said solution into a spray; c) drying said spray with hot air in order to evaporate the water; and d) separating the dried rhEPO from the drying air, wherein the aqueous solution of rhEPO contains no salts or other additives.
Patent NZ-310366-A (NZ)
Title: Haemopoietic growth factor antagonists and uses therefor
Inventor: VADAS MATHEW ALEXANDER
IPC: A61K45/00
Filed: 1996-06-21
Abstract: The present invention relates generally to variant recombinant forms of haemopoietic growth factors useful as antagonists to the corresponding native haemopoietic growth factor and their use in ameliorating aberrant effects caused by the native molecules and in the treatment of tumours and cancers and inflammation.
Patent NZ-313576-A (NZ)
Title: Stable solid formulation of enalapril salt and process for preparation thereof
Inventor: SHERMAN BERNARD CHARLES
IPC: A61K31/4015
Filed: 1996-07-30
Abstract: There is disclosed a stable pharmaceutical solid composition comprising enalapril as the sodium salt, which is made by the steps of: i) mixing enalapril maleate with a carrier, an alkaline sodium compound, and water; ii) drying the wet mass; iii) further processing the resultant dried mass into tablets. When the water is added in the aforesaid process, an acid-base reaction occurs which converts the enalapril maleate into the more stable enalapril sodium salt.
Patent NZ-333410-A (NZ)
Title: Process for the preparation of 17-esters of 9alpha,21-dihalo-pregnane-11beta,17alphadiol-20-ones
Inventor: KWOK DAW-IONG ALBERT
IPC: C07J7/00
Filed: 1997-06-25
Abstract: The application provides a process for the preparation of 17-esters of 9a,21-dihalo-pregnane-11b,17a-diol-20-ones, and in particular for the preparation of 17-esters of anti-inflammatory steroids of Figure I, where COR is a carboxylic acid group, R1 is H or lower alkyl, X and Y each are F, Cl or Br and the dotted line indicates a single or double bond. The process is especially suitable for the preparation of Mometasone Furoate.
Patent NZ-333811-A (NZ)
Title: Phase control device comprising switches interconnected by first and second conducting lines and connected to phase shift elements by the second conducting lines
Inventor: LEVI SHEM-TOV
IPC: H01Q3/34
Filed: 1996-07-25
Abstract: A phase control device 60, capable of providing a plurality of phase values, comprises a plurality of electrically interconnected phase shift elements 62 and a plurality of switches 66 electrically interconnected by a plurality of first conducting lines 68 and a plurality of second conducting lines 70.  The plurality of switches are electrically connected to the plurality of phase shift elements by means of the plurality of second conducting lines.  The phase shift elements and switches may be partitioned into phase control units.  The phase control units may be parallelly or serially connected or some of the units may be serially connected and others parallelly connected.  The phase control units may be connected to the switches of a further phase control.
Patent NZ-335871-A (NZ)
Title: Roll of material comprising a hollow plastic core with an adhesive-coated outer surface
Inventor: SCHURIG KARL
IPC: B65D85/672
Filed: 1999-05-20
Abstract: roll 10 of material 12, e.g. strap material for packages, is claimed.  The roll comprises a hollow core 11 made of a flexible plastic strip.  The ends of the strip are connected in mutually overlapping manner.  The outer surface 11a of core 11, facing material 12 to be wound thereon, is of a nature to oppose material 12 slipping thereon.  The plastic strip consists of an adhesive-coated foil, the adhesive-fitted surface of which faces material 12 and constitutes outer surface 11a of the core.
Patent NZ-336785-A (NZ)
Title: Optical device for converting N-bit serial optical signal into N-bit parallel optical signal
Inventor: BOFFI PIERPAOLO
IPC: H03M9/00
Filed: 1999-07-16
Abstract: An N-bit phase-modulated optical sequence 1000 is converted into an N-bit optical sequence 3000 in serial-to-parallel converter 61.  The parallel signal is then passed to a phase delay element 62 that is capable of causing a phase delay of at least one of the bits in the signal, the value of the phase delay being preselected on the basis of a predetermined N-bit sequence that the input signal is to be compared with.  The phase delay element 62 may be asynchronous, and may be a spatial light modulator or a phase mask.
Patent NZ-337922-A (NZ)
Title: Laparoscopic sealant applicator having shaft end able to be articulated from handle
Inventor: TRUMBULL HORACE R
IPC: A61B1/00
Filed: 1998-03-27
Abstract: A laparoscopic applicator device (10) for the selective directional application of one or more liquids to a surgical site is disclosed. The device (10) comprises a handle (12) with liquid inlets (16, 18, 20) at one end, discrete channels within one or more tubes (21) connecting with said inlets (16, 18, 20) extending through said handle (12) to a nozzle (22), and a dual injection shaft (14) at the nozzle end for inserting the shaft (14) and nozzle (22) through a surgical trocar. The dual shaft (14) comprises a rigid portion immediately adjacent the handle (12) and a flexible portion near the nozzle tip. Means are provided preferably within the handle (12), for the controlled articulation of the flexible shaft (14)/nozzle (22) assembly, thereby providing application of the liquids in a desired direction. The present invention is particularly useful in the application of surgical sealants, e.g., fibrin sealants. Methods of applying such components are also a part of the invention.
Patent NZ-500159-A (NZ)
Title: Detoxified mutants of bacterial adp-ribosylating toxins as parenteral adjuvants
Inventor: BARCHFELD GAIL
IPC: A61P31/04
Filed: 1998-03-19
Abstract: A parenteral adjuvant composition comprising a)	a detoxified cholera toxin mutant or a detoxified E. coli heat-labile toxin mutant as the parenteral adjuvant and b)	at least one selected antigen  The detoxified mutant consists of amino acid deletions, additions or substitutions in the A subunit of the bacterial holotoxin, preferably CT-S109, LT-K63 or LT-R72.  The composition can be used for immunizing a non-human vertebrate subcutaneously, transcutaneously or intramuscularly.