baber/WOPTO huggingface dataset:
Patent CA-2672176-A1 (CA)
Inventor: KOBASHI YOHEI
IPC: A61P25/00
Filed: 2007-12-14
Abstract: Disclosed is a 1-phenyl 1-thio-D-glucitol compound having the formula (I) or the like, a pharmaceutically acceptable salt thereof, a hydrate of the compound or the pharmaceutically acceptable salt, or a pharmaceutical agent comprising the compound, the pharmaceutically acceptable salt or the hydrate as an active ingredient, which can inhibit both the activities of SGLT1 and SGLT2 and has both of an effect of inhibiting the absorption of glucose through a digestive tract and an urinary glucose excretion effect, and therefore is useful as a new type of prophylactic or therapeutic agent for diabetes, a diabetes-related disease or a diabetic complication.
Patent CA-2672232-A1 (CA)
Inventor: CHAMORRO DAVALOS FRANCISCO CARLOS
IPC: H01R13/58
Filed: 2007-12-05
Abstract: A connector for use in terminating communications cables including electrical contacts (42) arranged to receive wires (30) of a communications cable (60), at least one cover (12, 22) pivotally connected with the connector and having wire-receiving spaces (14, 24), wherein the cover is arranged to move pivotally to bring wires positioned in its wire-receiving spaces into engagement with the contacts (42).
Patent CA-2674680-A1 (CA)
Title: Power distribution system secure access communication system and method
Inventor: HARRIS LAURENCE N
IPC: H04L29/06
Filed: 2007-12-10
Abstract: A power distribution system may have source, switching and load components, wherein at least one of the source, switching and load components has a wireless communication capability such that it is operable to act as a wireless communication access point. A mobile station seeking to associate with the one component may use a secure access protocol to gain such access. The secure access protocol may provide for receiving at the one component a management message from the mobile station. From the management message the component may obtain mobile identification information used to verify the identity of the mobile station and to initiate communication by sending an association message. Until after successful verification of the mobile station identity the component remains radio silent.
Patent CA-2674881-A1 (CA)
Inventor: SCHEIFLINGER FRIEDRICH
IPC: A61K38/36
Filed: 2008-01-29
Abstract: The present invention relates to recombinant blood coagulation factor IX (rFIX) mutants having factor VIII (FVIII) independent factor X (FX) activation potential. Five full length FIX proteins with combinations of mutations of amino acids important for functional activity of FIX and FIX wild type were cloned and expressed in HEK 293 cells. The proteins were tested by an activated partial thromboplastin time (aPTT) assay in FVIII-depleted plasma as well as in FVIII-inhibited patient plasma. In FVIII-depleted plasma functional activity of the FIX mutants was calculated as increased FVIII equivalent activity. The mutant proteins had increased FVIII equivalent activity. In FVIII-inhibited patient plasma the FEIBA equivalent activity was calculated for analysis of FVIII independent FX activation potential. The proteins had also increased FEIBA equivalent activity. Furthermore, the pre-activated FIX proteins had an increased activity in FIX-depleted plasma containing FVIII inhibitors. Therefore these FIX mutants are alternatives as bypassing agents for treatment of FVIII inhibitor patients.
Patent CA-2675103-A1 (CA)
Inventor: CLAVEAU FABIEN
IPC: G01N33/48
Filed: 2007-01-29
Abstract: There is described a system (2) and a method for analyzing spots in a micro-array (5), the spots containing targeted specimen, the method comprising the steps of: providing a slide with a micro-array of the spots thereon; illuminating at least one of the spots (500, 501); directing the light onto the at least one spot; collecting light emitted from the at least one spot; forming an image of the at least one spot using the collected light (502); and analyzing the image to distinguish at least one unit of the targeted specimen located within the at least one spot from any undesired material (506, 507). The analysis results are aimed at the detection, classification and quantification of optically resolvable specimen such as micro-organisms or cells.
Patent CA-2676172-A1 (CA)
Title: Pharmaceutical compositions comprising 2-methoxy-5-(5-trifluoromethyl-tetrazol-1-yl-benzyl)-(2s-phenyl-piperidin-3s-yl-)
Inventor: LARGE CHARLES
IPC: A61K31/4015
Filed: 2008-01-21
Abstract: The present invention relates to pharmaceutical compositions comprising an NK1 receptor antagonist and a sodium channel blocker compound of formula (I) wherein R1 and R2 are independently hydrogen, C1-6alkyl or C3-6cycloalkylC1-6alkyl; or R1 and R2, together with the nitrogen to which they are attached, may form an unsubstitued 3-, 4-, 5- or 6-membered saturated ring; R3 is C1-6alkyl, C1-6haloalkyl, C1-3alkoxyC1-3alkyl or C1-3haloalkoxyC1-3alkyl; or R1 and R3, together with the interconnecting atoms, form a saturated or unsaturated 4- to 6-membered ring; X is carbon or nitrogen; n is 0, 1 or 2, wherein when present each R4 is independently selected from the list consisting of C1-3alkyl, halogen, cyano, haloC1-3alkyl, hydroxy, C1-3alkoxy and C1-3haloalkoxy; q is 1 or 2; either R5 or R6 is -O-R7 or -OCH2R7, wherein the other R5 or R6 is hydrogen or R4; and wherein R7 is either a phenyl ring or a 5- or 6-membered aromatic heterocyclic ring (independently containing one or more nitrogen, sulphur or oxygen atoms) wherein either the phenyl ring or the heterocyclic ring is optionally substituted by one or more groups independently selected from the list consisting of C1-3alkyl, halogen, cyano, haloC1-3alkyl, hydroxy, C1-3alkoxy and C1-3haloalkoxy; or a pharmaceutically acceptable salt or solvate thereof; as a combined preparation for simultaneous or sequential administration, and to the use of such compositions in the treatment of certain disorders, including epilepsy and mood disorders.
Patent CA-2676611-A1 (CA)
Inventor: COLLINS DANIEL P
IPC: A61K39/395
Filed: 2008-01-24
Abstract: The invention provides compositions and methods for cell separation. These reagents and techniques specifically agglutinate cells via surface antigen recognition and can be used to recover even rare cell types in high yield.
Patent CA-2677505-A1 (CA)
Inventor: TARDIF GILLES
IPC: G07B15/02
Filed: 2009-09-02
Abstract: A device for collecting items from a container comprises a collection unit, a conduit, a vacuum producing unit and a controller. The conduit is in fluid communication with the collection unit and is mountable to the container so as to be placed in fluid communication therewith. The vacuum producing unit produces a vacuum within the conduit. The controller is linked to the vacuum producing unit and is configured to acquire data regarding the contents of the container. When the controller receives data regarding the contents of the container it controls the vacuum producing unit to modulate the vacuum produced within the conduit thereby suctioning the items within the container when mounted thereto into the collection unit. The container can be a transit fare box for receiving items tendered for fare. The data regarding the contents of the container can be the volume of items within the container.
Patent CA-2677754-A1 (CA)
Title: Temperature transfer filter plate assembly
Inventor: MARCHEK KENNETH
IPC: B01D37/00
Filed: 2008-02-11
Abstract: A temperature transfer filter plate assembly for a filter press includes a temperature transfer filter plate in a filter plate assembly having a plate chamber for receiving heating or cooling fluid. A plurality of apertures extend through the filter plate to enable the flow of liquid therethrough. A filter frame includes a web or divider wall that receives temperature transfer filter plates on opposing sides thereof. The apertures of each temperature transfer filter plate open into respective collecting chambers defined by the inner wall of the temperature transfer filter plate and the divider wall. A flow path arrangement allows removal of the liquid from the collecting chambers in the temperature transfer filter plate assembly. The temperature transfer filter plates generally have inner and outer walls with a wavy or undulating configuration to form the plate chamber therebetween.
Patent CA-2679066-A1 (CA)
Title: Hydroxylamine compounds and methods of their use
Inventor: PATIL GHANSHYAM
IPC: C07D409/12
Filed: 2008-02-15
Abstract: The present disclosure provides compounds that include hydroxylamines of formula (I) or (II), pharmaceutical compositions, and methods for their use. The methods utilize hydroxylamine compounds and/or their pharmaceutical compositions for the treatment of angiogenesis, hepatitis, complement-mediated pathologies, drusen-mediated pathologies, macular degeneration and certain other ophthalmic conditions, inflammation, arthritis, and related diseases and for the inhibition of complement activation.
Patent CA-2682550-A1 (CA)
Title: Peripheral opioid receptor antagonists and uses thereof
Inventor: LOKHNAUTH JOHN
IPC: C07D471/08
Filed: 2008-03-28
Abstract: The present invention provides a compound of formula I wherein X-, R1, and R2 are as defined herein, and compositions thereof, useful as a peripheral mu opioid receptor antagonist.
Patent CA-2683112-A1 (CA)
Title: Split-cycle four-stroke engine
Inventor: BRANYON DAVID P
IPC: F02B41/06
Filed: 2004-06-14
Abstract: An engine (100) has a crankshaft (108), rotating about a crankshaft axis (110) of the engine (100). An expansion piston (114) is slidably received within an expansion cylinder (104) and operatively connected to the crankshaft (108) such that the expansion piston (114) reciprocates through an expansion stroke and an exhaust stroke of a four stroke cycle during a single rotation of the crankshaft (108). A compression piston (116) is slidably received within a compression cylinder (106) and operatively connected to the crankshaft (108) such that the compression piston (116) reciprocates through an intake stroke and a compression stroke of the same four stroke cycle during the same rotation of the crankshaft (108). A ratio of cylinder volumes from BDC to TDC for either one of the expansion cylinder (104) and compression cylinder (106) is substantially 20 to 1 or greater.
Patent CA-2684583-A1 (CA)
Title: Fluidic control system and method of manufacture
Inventor: IACONIS JEAN LOUIS
IPC: F16L41/02
Filed: 2008-03-25
Abstract: A fluidic control system includes featured layers. The featured layers include two or more features which collectively form at least one functional component.
Patent CA-2685495-A1 (CA)
Title: Mutated e. coli heat-labile enterotoxin
Inventor: YUAN TA-TUNG
IPC: A61K39/02
Filed: 2007-08-13
Abstract: This invention relates to a mutant E. coli heat-labile enterotoxin (LT) subunit A that can be used as an adjuvant. This subunit A mutant contains an amino acid substitution at a position corresponding to position 61 of a wild-type LT. An LT containing this mutated subunit A exhibits reduced toxicity compared to its wild type counterpart.
Patent CA-2686482-A1 (CA)
Inventor: CSUTAK SEBASTIAN
IPC: G01V1/40
Filed: 2008-05-02
Abstract: A sensor adapted for measuring acceleration, the sensor including a light source for illuminating an optical cavity; the optical cavity oriented for receiving light from the source, the optical cavity comprising a quality factor greater than or equal to about 10,000; and a photodetector for measuring a resonant frequency of light emitted from the optical cavity.
Patent CA-2686814-A1 (CA)
Title: Retrograde resection apparatus and method
Inventor: BRIGHTMAN TIMOTHY
IPC: A61B17/00
Filed: 2007-12-11
Abstract: A retrograde resection apparatus may include a cutting blade including a slot defined in the cutting blade, a recess defined in at least a portion of the slot, a screw, including a proximal end and a distal end defining a bore therethrough, a shaft having a distal end and a proximal end, wherein the shaft passes through the bore and the distal end is configured to be received in the recess, and a biasing device configured to bias the shaft against the cutting blade. In addition, the apparatus may include a tether, a first portion of which is affixed to the cutting blade and a second portion of which passes through the bore.
Patent CA-2688983-A1 (CA)
Inventor: MCGUFFIN THOMAS F
IPC: H04W40/12
Filed: 2009-12-22
Abstract: A method for selecting a ground station for communication with an aerial vehicle is provided. The method comprises receiving at an aerial vehicle one or more messages from one or more ground stations. The method includes storing one or more signal strength values corresponding to the one or more received messages in a data structure for each respective one or more ground stations received during a predefined time period. The data structures for each of the one or more ground stations is updated. The average of the signal strength values stored in each data structure is calculated. The method compares the average signal strength of each of the one or more ground stations and selects which ground station the aerial vehicle is to communicate with based on predefined criteria.
Patent CA-2690769-A1 (CA)
Inventor: BETTUCHI MICHAEL
IPC: A61B17/03
Filed: 2010-01-21
Abstract: An access port provides passage into a subject's body. This access port generally includes a housing and a suture management system. The housing defines a longitudinal axis and has a longitudinal passage. The longitudinal passage is adapted to allow passage of a plurality of sutures through the housing. The suture management system, which is operatively coupled to the housing, includes a flapper having a plurality of spaced apart recesses. Each recess includes an insert disposed in mechanical cooperation therewith, and each insert has a slit configured to receive and hold at least one suture of the plurality of sutures.
Patent CA-2691782-A1 (CA)
Inventor: LIU HUAQING
IPC: A61K31/501
Filed: 2008-09-11
Abstract: The invention relates to octahydro-pyrrolo[3,4-b]pyrrole N-oxides as prodrugs of CNS-active compounds, compositions comprising such compounds, methods for making the compounds, salts, and polymorphs, and methods of treating conditions and disorders using such compounds and compositions. Octahydro-pyrrolo[3,4-b]pyrrole N-oxides of formula (I) are prodrugs of histamine-3 antagonists, and are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands.  Octahydro-pyrrolo[3,4-b]pyrrole N-oxide compounds, methods for using such compounds, compositions for making them, and processes for preparing such compounds are disclosed herein.
Patent CA-2693097-A1 (CA)
Inventor: MOE SIGURD T
IPC: G08B21/12
Filed: 2008-07-16
Abstract: To achieve gas detection in a precise and reliable way, but at the same time without consuming too much energy, a gas detection system is provided which generally comprises a pair of two different gas detectors.  The first detector (D LP) is active continuously and sense substantially for an unspecific change in the local gas mixture.  As a reaction upon the change, the second detector (D HP) of the pair is activated. This detector (D HP) performs the determination of the concentration of a specific gas or several specific gasses.  The second detector (D HP) may be of a type which consumes more power, but will be active for a short period of time before returning to an inactive state where only the first detector (D LP) is active. The first detector (D LP) however is of a type using little power.
Patent CA-2697083-A1 (CA)
Inventor: SOLEIMANI MOHAMMAD
IPC: G06K7/00
Filed: 2008-08-13
Abstract: A thermal management system and method to control temperature in an RFID  reader is described herein. In par-ticular, by inserting variable periods of inactivity (or latency) at the beginning or at the end of each read cycle, proportional to an instantaneous temperature value of the RFID reader, over-heating and damage of RFID reader electronics is prevented. The RFID reader includes a thermal sensor and determines when the high power RF  electronics is enabled. If the RFID reader is in an over-heated condition, it can be turned OFF and during this period any requests received on an interface to the RFID reader to perform a read of tag(s) are not processed.
Patent CA-2697142-A1 (CA)
Inventor: SMITH DANIEL JOHN
IPC: B29C48/09
Filed: 2001-05-08
Abstract: A breathing circuit component includes an inlet, an outlet and an enclosing wall. The enclosing wall defines a gases passageway between the inlet and the outlet. At least a region of the enclosing wall is formed from a breathable material that allows the passage of water vapour without allowing the passage of liquid water or respiratory gases. The breathing circuit component may be the expiratory limb of a breathing circuit.
Patent CA-2697530-A1 (CA)
Inventor: ANDERSON GORDON
IPC: E04F15/02
Filed: 2008-09-18
Abstract: A floor covering system (10) including a first layer (14) of planar material and a second layer (12) of planar material. At least a portion of the second layer (12) is adapted for laminating engagement with the first layer (12) to define a floor covering. The system further includes a locating means for locating two or more of the second layers in a substantially aligned configuration, wherein the second layer (12) is adapted to receive the locating means.
Patent CA-2698906-A1 (CA)
Inventor: WOODHOUSE SIMON
IPC: B01D53/14
Filed: 2008-09-15
Abstract: A method for regeneration of a rich absorbent having absorbed CO2, to give a regenerated, or lean absorbent, and CO2, is described. The rich absorbent is brought in countercurrent flow with steam at least partly generated by heating lean absorbent in a reboiler at the base of the regeneration column, where released CO2 and steam are withdrawn from the top of the column. Lean, or re-generated absorbent is withdrawn from the base of the column, and is flashed over a flash valve and separated in a flash tank into a gas phase, that is compressed and returned into the regenerator column, and a liquid phase mainly comprising lean absorbent that is cooled by heat exchanging against incoming rich absorbent, wherein the gas phase and/or the lean absorbent is/are heat exchanged against a low temperature heat medium after leaving the flash valve.
Patent CA-2699138-A1 (CA)
Inventor: JENKINS PAUL
IPC: A61K31/00
Filed: 2008-10-03
Abstract: The present invention relates to compounds, as well as to compositions, methods and kits comprising such compounds, for use in the treatment or prophylaxis of fibromyalgia, chronic fatigue syndrome, myofascial pain syndrome, Gulf War syndrome and related conditions, wherein the compound is a fatty acid oxidation inhibitor and/or a carbohydrate oxidation activator.
Patent CA-2699146-A1 (CA)
Inventor: SIPPOLA PERTTI J
IPC: C23C2/02
Filed: 2008-09-09
Abstract: The present invention is directed to a method and apparatus of producing a dual-phase galvanized steel strip with improved formability while maintaining a high tensile strength. The present invention comprises a step of cooling and a step of reheating. In the cooling step, the galvanized steel strip has a temperature reduction of from about 3000C  to about 1500C-2500C. This step of cooling should cool to a maximum extent of about 1500C different between the initial temperature and the final temperature. This cooling may be accomplished by a hot water quench, or the use of a cooling tower, or other means. The step of reheating should follow the step of cooling. The step of reheating should heat the galvanized steel strip to a temperature of about 340°-390°C.  This reheating causes the martensite in the galvanized steel strip to be tempered at a relatively low temperature, which reduces the Fe-Zn phase formation in the GI-coating.
Patent CA-2701176-A1 (CA)
Title: Method and system to measure the concentration of constituent elements in an inhomogeneous material using libs
Inventor: LEVESQUE MARC
IPC: G01N21/71
Filed: 2008-04-04
Abstract: A system and method to improve the accuracy of the measure of constituent element(s) in a sample containing domains potentially including the constituent element(s) are described herein.  For each domain, the volume of the domain is estimated and the concentration of the constituent element(s) in the domain is determined using LIBS. When all the domains have been analyzed, the volumetric concentration of the domains is summed and divided by the total volume of the sample. Accordingly, by limiting the concentration analysis to separate domains, it is possible to improve the accuracy of the concentration analysis.
Patent CA-2702298-A1 (CA)
Inventor: WONG PETER
IPC: G02B6/00
Filed: 2008-10-09
Abstract: The present invention provides systems, devices, and methods employing fiber optic shape and position tracking. The systems, devices, and methods permit measurement of and continuous tracking of the shape and position of objects whose shape dynamically changes with time. Applications include tracking and monitoring of endoscopes for diagnostic and surgical procedures.
Patent CA-2702632-A1 (CA)
Title: Protecting against incorrect battery polarity
Inventor: LARSEN GLEN C
IPC: H01M50/296
Filed: 2008-10-29
Abstract: Embodiments of battery holders with dual-contact assemblies are disclosed. One embodiment comprises a battery holder with a substrate and a spring dual-contact assembly, wherein the spring dual-contact assembly comprises a positive contact configured to contact a positive terminal of a battery positioned in the battery holder with the positive terminal oriented toward the spring dual-contact assembly and a negative contact configured to contact a negative terminal of a battery positioned in the battery holder with the negative terminal oriented toward the spring dual-contact assembly. The positive and negative contacts are coupled to an insulator configured to hold the positive contact and negative contact in a fixed relation to one another. Further, one or more cantilever wire springs hold the negative contact, positive contact and insulator in a resiliently displaceable relationship to the substrate.
Patent CA-2703324-A1 (CA)
Inventor: SCHOELL GEORGE
IPC: E04F13/18
Filed: 2010-05-06
Abstract: A system for a solar panel roof surface effectively uses a roof support substructure having a series of parallel hollow support beams extending downwardly from a roof peak to a roof edge. These parallel hollow beams not only provide support for solar panels but also allow for drainage in channels provided in the beams. A series of solar panels are secured to hollow support beams and collectively define a closed sloped roof surface. The series of solar panels are positioned on the beams to define elongate segments of abutting panels where each elongate segment is one panel wide and supported between adjacent hollow support beams.  The abutting panels include a sealing arrangement between panels to allow flow of water along the length of the elongate segments. Preferably, the series of hollow support beams include a top surface with a central securing slot positioned between panel segments and panel segment support surfaces either side of said securing slot for supporting edges of the solar panels with at least one drainage channel in the top surface and extending the length of the support beam for draining of water received in the channel to the roof edge.
Patent CA-2703653-A1 (CA)
Inventor: BARLAAM BERNARD CHRISTOPHE
IPC: A61P35/00
Filed: 2008-10-22
Abstract: The invention concerns pyridine a nd pyrazine derivatives of Formula (I) or a pharmaceutically-acceptable salt thereof, wherein each of W, Gl, G2, G3, G4, J, Ring A, n and R3 has any of the meanings defined hereinbefore in the description;  processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders.