baber/WOPTO huggingface dataset:
Patent EP-4183409-A1 (EP)
Title: Vaccine with improved immunogenicity against mutant coronaviruses
Inventor: CICHON GÜNTER
IPC: A61K39/12
Filed: 2021-11-17
Abstract: The invention relates to an isolated nucleic acid molecule encoding a variant spike (spike-like) protein of a corona virus or fragment thereof wherein the variant spike protein comprises an amino acid sequence with at least two amino acid differences over SARS-CoV-2 "Wuhan Sequence", and wherein said variant spike protein comprises amino acid differences over SARS-CoV-2 "Wuhan Sequence" from at least two of the B.1.1.7 (alpha-variant), B.1.351 (beta-variant), B.1.1.28 (gamma-variant), B1.617.2 (delta-variant), and C.37 (lambda-variant) spike proteins. The variant comprises an amino acid sequence comprising preferably at least four amino acid differences over SARS-CoV-2 "Wuhan Sequence" being capable of inducing an immunogenic response in a human subject against a human coronavirus and variants thereof. In further aspects, the invention relates to a pharmaceutical composition in the form of a vaccine for use in the prevention and/or reduction of risk of a human coronavirus infection. The invention further relates to the medical use and corresponding methods of administering a vaccine of the invention in the reduction of risk of a human coronavirus infection and/or prevention of a medical condition associated with coronavirus, in particular SARS-COV-2 and SARS-CoV-2 variants.
Patent EP-4014778-A1 (EP)
Title: Kopfschutz
Inventor: BAUMEISTER ANDREA
IPC: A42B3/04
Filed: 2021-11-18
Abstract: Die Erfindung betrifft einen Kopfschutz zum Schutz eines Kopfschutz-Trägers. Der Kopfschutz hat einen Grundkörper (1), mindestens einen an dem Grundkörper (1) angeordneten Airbag (4) und eine an dem Grundkörper (1) angeordnete und mit dem mindestens einen Airbag (4) zumindest zeitweise in Verbindung stehende Unfall-Erfassungsanordnung zum Auslösen des mindestens einen Airbags (4) bei einem erkannten Unfall. Die Unfall-Erfassungsanordnung weist mindestens eine 3D-Umgebungs-Erfassungseinrichtung (2) zum Erfassen einer jeweiligen Umgebung des Kopfschutz-Trägers und mindestens eine Bewegungs-Erfassungseinrichtung (7) zum Erfassen einer jeweiligen Bewegung des Kopfschutz-Trägers auf. Sie veranlasst eine Auslösung des mindestens einen Airbags (4), wenn die jeweilige erfasste Bewegung und die jeweilige erfasste Umgebung beide zusammen auf einen Unfall schließen lassen.
Patent EP-4166855-A1 (EP)
Inventor: KONG TAO
IPC: F24F1/00
Filed: 2021-11-23
Abstract: There is provided an air processing device (100) comprising: an inlet (102); an outlet (104); a conduit (106) for air to pass between the inlet and the outlet; a fan (120) for driving a flow of air through the conduit between the inlet and the outlet; at least one air processing component (130) selected from: an air filter (132) arranged to filter air passing between the inlet and the outlet; and one or more components (134, 136) for adjusting a concentration of water vapour within the air passing between the inlet and the outlet, wherein the air processing device further comprises: a heater (142); and one or more ducts (144) for carrying heated air from the heater to one or more of the air processing components and/or the outlet respectively, wherein the ducts are arranged to introduce the heated air into the conduit between the inlet and the outlet.
Patent EP-4023654-A1 (EP)
Inventor: CHOI SU-NA
IPC: H01L51/50
Filed: 2021-11-29
Abstract: An emitting compound and an organic light emitting device includeing the emitting compound.
Patent EP-4008318-A1 (EP)
Inventor: PEHLIVAN AKALIN NUR
IPC: A61K9/28
Filed: 2021-12-02
Abstract: The present invention relates to a process for the preparation of a film coated tablet formulation comprising amorphous dapagliflozin and metformin hydrochloride. The process is wet-granulation which is simple, rapid, cost effective, time-saving and industrially convenient process and is created to eliminate the disadvantages of both active ingredients.
Patent EP-4015166-A1 (EP)
Title: Folding knife with selectively hidden blade release
Inventor: EBERT KARA
IPC: B26B5/00
Filed: 2021-12-13
Abstract: Certain embodiments of a folding knife 100 are disclosed. In one embodiment, an example knife may include a handle 102 and a blade carrier 104. The blade carrier may be rotatable about the handle and may include a left and a right cap 114, 116. A blade 106 may be removably disposed within the blade carrier. The knife may further include a blade release mechanism 110. In one embodiment, the blade release mechanism may include a compression spring 118 and a lift bar 120. In another embodiment, the blade release mechanism may further include a wheel 1122. In yet another embodiment, the blade release mechanism may include a leaf spring 718 and a slide bar 720. When the blade carrier is rotated such that the knife is not in a cutting position, at least a portion of the blade release mechanism is exposed. When the blade release mechanism is activated, the blade may be removed from within the blade carrier.
Patent EP-3989474-A1 (EP)
Title: Channel width indication in edmg capabilities and edmg operations elements in 802.11ay
Inventor: XIN YAN
IPC: H04L27/26
Filed: 2018-02-02
Abstract: Methods for communicating support of operations or capabilities for enhanced directional multi-gigabit (EDMG) communications are described. A supported channel width field or operating channel width field is used in a capabilities element or operation element. The supported channel width field or operating channel width field includes bit positions with bit values that are set to indicate support of operation or a capability of the transmit device from among defined options, the defined options including: the transmit device can perform channel bonding only, the transmit device can perform carrier aggregation only, and the transmit device can perform both channel bonding and carrier aggregation.
Patent EP-4197449-A1 (EP)
Title: Fluoroscopic positioning guidance
Inventor: VON BERG JENS
IPC: A61B6/00
Filed: 2021-12-20
Abstract: The present invention relates to patient positioning. In order to facilitate patient positioning, an apparatus is provided that comprises an input unit, a processing unit, and an output unit. The input unit is configured to receive an X-ray image of an anatomy of interest of a patient obtained from a first image acquisition and a target set of pose parameters describing a target position of the anatomy of interest for image acquisition. The processing unit is configured to detect the anatomy of interest in the X-ray image, to determine a set of pose parameters describing a current position of the detected anatomy of interest in the first image acquisition, to determine a difference between the determined set of pose parameters and the target set of pose parameters, and to construct a trajectory that defines a sequence of sets of pose parameters for bringing the anatomy of interest from the current position to the target position, if the difference is equal to or greater than a pre-defined threshold. The processing unit is further configured to generate a series of X-ray images according to the received X-ray image and the sequence of sets of pose parameters in the trajectory to synthesize a virtual fluoroscopic image sequence of frames representing an animated radiographic imaging during re-positioning of the patient. The output unit is configured to provide the synthetic virtual fluoroscopic image sequence for positioning guidance for a second image acquisition.
Patent EP-4202348-A1 (EP)
Inventor: HELL SEBASTIAN
IPC: F41A3/66
Filed: 2021-12-23
Abstract: Die Erfindung betrifft eine Griffstückbaugruppe (3) für eine Handfeuerwaffe (1), die Griffstückbaugruppe (3) umfassend:- ein Griffstückoberteil (6), wobei das Griffstückoberteil (6) eine Schlittenführung (12) zur Aufnahme einer Schlittenbaugruppe (2) aufweist, wobei das Griffstückoberteil (6) einen Magazinaufnahmeraum (8) zur Aufnahme eines Magazines (9) aufweist, wobei der Magazinaufnahmeraum (8) eine Magazineinführrichtung (10) definiert, wobei im Gebrauchszustand der Handfeuerwaffe (1) das Magazin (9) in Magazineinführrichtung (10) in den Magazinaufnahmeraum (8) einschiebbar ist;- ein Griffstückunterteil (7), wobei das Griffstückunterteil (7) in der Magazineinführrichtung (10) auf das Griffstückoberteil (6) aufschiebbar und mit diesem koppelbar ist;- ein Arretiermechanismus (13) zum Koppeln des Griffstückunterteils (7) mit dem Griffstückoberteil (6). Der Arretiermechanismus (13) umfasst ein baulich eigenständig ausgebildetes Arretierelement (14), wobei das Arretierelement (14) einen Anlagevorsprung (15) aufweist, welcher formschlüssig in das Griffstückunterteil (7) eingreift und wobei das Arretierelement (14) einen Arretiervorsprung (17) aufweist, welcher formschlüssig in das Griffstückoberteil (6) eingreift.
Patent EP-4080892-A1 (EP)
Title: Method for playing on a player of a client device a content streamed in a network
Inventor: YOUSEF HIBA
IPC: H04N21/63
Filed: 2021-04-20
Abstract: The present invention relates to a method for playing on a player of a client device (11) a content streamed in a network (1), said content consisting of a sequence of segments available in a plurality of quality levels, the player being configured to request segments at a selectable quality level; the method being characterized in that it comprises performing by a processing unit (110) of the client device (11):(a) obtaining from the network (1) a model approximating an Adaptive BitRate, ABR, logic for choosing said quality level of the segments as a function of at least one parameter representative of a segment reception rate;(b) determining, according to said obtained model, a first quality level at which the player would have requested a current segment if the player was applying said ABR logic;(c) configuring the player to select said first quality level as quality level for requesting segments.
Patent EP-4116188-A1 (EP)
Title: Aerofoil of an aerodynamic surface
Inventor: JARA RODELGO ÁLVARO
IPC: B64C3/50
Filed: 2021-07-05
Abstract: The present invention is related to an aerofoil (1) of an aerodynamic surface (10), the aerofoil comprising: a control surface (2) comprising an upper surface (2.2) and a lower surface (2.3), and an actuating means (3) configured to elevate or lower the control surface (2), and wherein at least a portion of one of the upper surface (2.2) and the lower surface (2.3) of the control surface (2) is auxetic with a negative Poisson ratio, and the other of the upper surface (2.2) and the lower surface (2.3) of the control surface (2) comprises a material with a higher Poisson ratio.
Patent EP-4160211-A1 (EP)
Title: Detecting the exposure of a subject to a thyroid disrupting chemical, even before hypothyroidism appears
Inventor: MORENO NAVARRO JOSÉ CARLOS
IPC: G01N33/76
Filed: 2021-09-29
Abstract: The invention relates to a method and biomarker for detecting the exposure of a subject to a Thyroid Disrupting Chemical, even before hypothyroidism appears, and the use thereof.
Patent EP-4087822-A1 (EP)
Inventor: CAIRNS DANIEL
IPC: C01G53/00
Filed: 2021-01-06
Abstract: L'invention concerne un procédé de production d'un oxyde de métal de transition de lithium. Le procédé comprend la pré-calcination d'un précurseur de métal de transition en l'absence d'une source de lithium suivie d'une calcination à haute température du composé intermédiaire pré-calciné en présence d'une source de lithium.
Patent EP-4090948-A1 (EP)
Title: Ir spectroscopic cell culture analysis
Inventor: HEGARTY MARK
IPC: G01N21/3577
Filed: 2021-01-15
Abstract: A method of detection of a status of cells within a cell culture is described. The method is based on comparing an IR spectrum of a test sample obtained from the cell culture with an IR spectrum of a control sample or samples or with an IR spectrum of a sample or samples obtained at an earlier time point in the cell culture and correlating differences between the spectra with the status of the cells. The status may be classified into healthy or unhealthy. The test sample may or may not contain cells. The test sample may contain cell fragments, cell components or cell media, or may be cell supernatant. The comparison may be performed using a predictive model based on pattern recognition algorithms, such as support vector machines SVM, linear discriminant analysis LDA, principal component discriminant function analysis PC-DFA, neural networks, or random forests). The analysis results may be used to monitor and/or control the cell culturing process.
Patent EP-4097814-A1 (EP)
Inventor: ZHOU XIN
IPC: H02H3/05
Filed: 2021-01-28
Abstract: A circuit interrupter including a current sensor having a normal sensor output and an over current detection output, a solid state switch module structured to have a closed state to allow current to flow through the circuit interrupter and an open state to interrupt current flowing through the circuit interrupter, a gate driver structured to control the solid state switch module including a desaturation function output, wherein the gate driver is structured to cause the solid state switch module to interrupt current flowing through the circuit interrupter when the DESAT function output changes to the on state, and an electronic trip circuit structured to output a trip signal to the gate driver when the normal sensor output reaches a first threshold level or the overcurrent detection output changes to the on state.
Patent EP-4115657-A1 (EP)
Inventor: YANG WEI
IPC: H04L1/18
Filed: 2021-03-02
Abstract: Methods, systems, and devices for wireless communications are described. The method, system, or devices for wireless communications may implement receiving a grant for a first transmission scheduled for a first set of resources, the first transmission associated with a first transmission parameter; receiving an indication to cancel the first transmission; dropping the first transmission based on receiving the indication; determining a second transmission parameter for a second transmission based on the first transmission parameter and irrespective of dropping the first transmission; and performing or receiving the second transmission according to the second transmission parameter. Alternatively, a device may receive an indication to cancel the second transmission; drop the second transmission based on receiving the indication; and refraining from rescheduling the first transmission on the first set of resources based on receiving the indication and irrespective of dropping the second transmission.
Patent EP-4133502-A1 (EP)
Inventor: WEGNER STEFAN
IPC: G16H40/40
Filed: 2021-04-08
Abstract: The present invention relates to a medical set comprising a transmitter device (160) and a user information device (500). The user information device (150) in turn has a determination device (501) and an evaluation device (509). The determination device (501) is programmed to determine a point in time relating to the process of puncturing a vessel of a patient (P) at the point in time (t P , t B ) for the purpose of an imminent or planned blood treatment by means of the blood treatment device (100) and to transmit the point in time (t P , t B ) to the evaluation device (509). The evaluation device (509) is programmed to transmit information regarding the determined point in time (t P , t B ) to the transmitter device (160) and/or programmed to determine a time period (T, T max ) on the basis of the determined point in time (t P , t B ) and to transmit the information regarding the determined time period (T, T max ) to the transmitter device (160). The transmitter device (160) is programmed to receive the information and to transmit a signal regarding the point in time or the time period (T, T max ) to a receiver device.
Patent EP-4118197-A1 (EP)
Inventor: CHEN FUQIANG
IPC: C12N9/22
Filed: 2021-03-11
Abstract: Engineered Cas9 protein variants and systems, nucleic acids encoding said protein variants and systems, and methods of making and using said protein variants and systems for genome modification.
Patent EP-4146250-A1 (EP)
Inventor: JORBA RIBES JAVIER
IPC: A61K38/38
Filed: 2021-04-27
Abstract: The present invention relates to a composition comprising albumin for use in the treatment of Amyotrophic Lateral Sclerosis (ALS), wherein the composition is administrated to the patient by plasma exchange using a volume of said composition equivalent to approximately 100 % of the volume of plasma withdrawn from the patient, and with a frequency of twice a week the first 3 weeks and once a week for the following 21 weeks, for a total period of 24 weeks.
Patent EP-4139533-A1 (EP)
Title: Melting-fuse description
Inventor: BERLEE ANTHONIE BERNARDUS
IPC: E04B1/80
Filed: 2021-04-22
Abstract: The melting-fuse may be a non-stable container that contains compressed or vacuumed mineral wool, such as stone wool, that is attached to the fixation details between building components that must be air- permeable that must then provide sufficient fire resistance. The application includes melting-fuses. The fuse works in two parts, first it holds the compressed or vacuumed mineral wool in the desired location, without this prematurely expanding and thus interrupting the necessary air flow. The second form of the fuse is designed for the fact that this melts first in the event of fire, after which the compressed or vacuumed mineral wool expands and seals the cavity. Through the melting of the fuse and the subsequent sealing of the detail / opening where the application is installed, the further spread of the fire through the air flow is prevented.
Patent EP-4125621-A1 (EP)
Title: Rib retractor with compliant retractor blade
Inventor: CATANIA PABLO HERNAN
IPC: A61B17/02
Filed: 2021-05-14
Abstract: A retractor blade includes a descender portion and a hook portion. The descender portion is configured to engage a rib in response to a retraction force applied to the retractor blade. The hook portion forms a channel with the descender portion. The channel is configured to secure the rib against the descender portion. The descender portion and the hook portion are integrally formed of a compliant material. The first hook portion includes at least one gap separating a plurality of teeth. The at least one gap of the hook portion and the compliant material together are configured to cause substantially an entire length of the retractor blade in the descender portion to conform to the rib in response to the retraction force. The retractor blade may be pivotably attached to an arm of a retractor that is configured to mechanically retract in response to the retraction force.
Patent EP-4172534-A1 (EP)
Inventor: KINGMAN DAVID E
IPC: B60Q3/208
Filed: 2021-06-08
Abstract: A system may have windows. A window may have a structural window layer such as a structural window layer formed from laminated glass layers. The window may separate an exterior region from an interior region within the vehicle. A light guide illuminator in the window may provide illumination for the interior region. The light guide illuminator may have a light guide that receives light from a light source. The light guide may have a density of light scattering structures that increases as a function of increasing distance from the light source so that the interior illumination is uniform across the light guide illuminator. An adjustable optical component layer such as a light modulator and/or a haze compensation layer with a density of light scattering structures that decreases as a function of distance from the light source may be interposed between the light guide and the structural window layer.
Patent EP-4091671-A1 (EP)
Title: Angiogenic agent and production method for extracellular vesicles having angiogenic effect
Inventor: ISHIDOME Takamasa
IPC: A61K35/34
Filed: 2021-01-14
Abstract: An object of the present invention is to provide a therapeutic preparation composed of a population of extracellular vesicles having a high therapeutic effect, particularly to provide an angiogenesis agent. The present invention relates to the angiogenesis agent containing a mesenchymal stem cell-derived extracellular vesicle, as an active ingredient, in which an extracellular vesicle is obtained by a method of using a substance that contains an extracellular vesicle having an affinity for phosphatidylserine, or/and an extracellular vesicle is derived from a mesenchymal stem cell stimulated with a growth factor, and relates to a method of producing an extracellular vesicle as the angiogenesis agent.
Patent EP-4097686-A1 (EP)
Title: A system and method for visualization of glass products
Inventor: TEJA V SAI
IPC: G06T17/00
Filed: 2021-01-21
Abstract: A system and method for visualization of glass products in real-time is disclosed. The method includes measuring dimension of a room by a hand-held measurement device. The room measurements are received by a server that triggers mapping of the measurements to related glass products. Thereafter, at least one selected glass product and parameters are received from a user through a graphical user interface of the computing device. The selected glass product made by the user is mapped to a catalogue glass product from a plurality of glass products stored in a database, where the chosen glass product is confirmed after verifying the glass products suited to the provided room measurements. A three-dimensional image of the chosen glass product is generated. Finally, th three-dimensional image of the chosen glass product is overlaid on the three-dimensional image of the room to create a panoramic and realistic 3D image of the product on a graphical user interface of the computing device. The method also includes providing one of a virtual display, augmented reality, and an immersive display of the glass product.
Patent EP-4188620-A1 (EP)
Inventor: ZHANG MING
IPC: G01N29/06
Filed: 2021-07-27
Abstract: L'invention concerne un dispositif (100) d'alimentation d'un transducteur ultrasonore (302) comprenant une interface de puissance (106) configurée pour fournir un signal analogique de puissance, dit signal d'alimentation, audit transducteur ultrasonore (302), caractérisé en ce qu'il comprend en outre un modulateur sigma-delta (104) configuré pour réaliser une modulation sigma-delta d'un signal sinusoïdal, dit de pilotage, et fournir un signal numérique, dit de commande, pour commander ladite interface de puissance (106). Elle concerne également un dispositif ultrasonore (300) alimenté par un tel dispositif d'alimentation, une tête ultrasonique comprenant de tels dispositifs ultrasonores et un système ultrasonore comprenant une telle tête ultrasonique.
Patent EP-4196842-A1 (EP)
Title: Low distortion imaging through a c-shape flat optical architecture
Inventor: DRAZIC VALTER
IPC: G02B27/42
Filed: 2021-08-10
Abstract: Embodiments include an optical system that may be included in a waveguide display. A waveguide apparatus according to some embodiments includes an in-coupler grating having a first grating vector G 1  substantially perpendicular to a first axis, x; a first eye pupil expander grating having a second grating vector G 2  and a first angle Φ G  with respect to the first axis; a second eye pupil expander grating having a third grating vector G 3  and an angle substantially equal to 90° + Φ G  with respect to the first axis; and an out-coupler grating having a fourth grating vector G4 substantially perpendicular to the first axis. Example embodiments describe relationships among the grating vectors, the angle Φ G , and associated parameters to achieve a satisfactory field of view while reducing distortion.
Patent EP-4200303-A1 (EP)
Title: Crystalline form of heterobicyclic compound
Inventor: MITA TAKASHI
IPC: A61K31/519
Filed: 2021-08-24
Abstract: An object of the present invention is to provide a crystal of compound 1, which is useful as an antitumor agent, the crystal being stable, excellent in oral absorbability, highly chemically pure, and suitable for mass production. The present invention provides a crystal of compound 1 that exhibits an X-ray powder diffraction spectrum containing, at diffraction angles 2θ±0.2°, characteristic peaks of at least 3 characteristic peaks selected from the group consisting of 5.8°, 9.8°, 12.2°, 14.0°, 15.3°, 21.1°, and 27.6°.