baber/WOPTO huggingface dataset:
Patent AU-2020330755-A1 (AU)
Title: Cells highly sensitive to clostridial neurotoxin
Inventor: OYLER GEORGE A
IPC: G01N33/542
Filed: 2020-08-13
Abstract: A method for making a population of cells that are highly sensitive to clostridial neurotoxin, the method comprising: (a) contacting recombinant cells that express an indicator protein with clostridial neurotoxin; and (b) following such contact, selecting the cells that exhibit cleavage of the indicator protein. A cell from the population produced using the aforementioned method. An assay for determining the activity of a modified or recombinant neurotoxin comprising contacting such a cell with the modified or recombinant neurotoxin under conditions and for a period of time sufficient to allow the protease domain of a wild-type clostridial neurotoxin to cleave the indicator protein in the cell and determining the presence of product resulting from the cleavage of the indicator protein.
Patent AU-2020355080-A1 (AU)
Title: Immunogenic peptide fragment of metalloproteinase ADAMTS-7 and application thereof in resisting against atherosclerosis and related diseases
Inventor: KONG WEI
IPC: A61P9/00
Filed: 2020-08-20
Abstract: An immunogenic peptide fragment of metalloproteinase ADAMTS-7 and an application thereof in resisting against atherosclerosis and related diseases. Provided is a short peptide, comprising any one of the following: a short peptide of which the amino acid sequence shown in sequence 1 in a sequence listing; a short peptide of which the amino acid sequence is shown in sequence 2 in the sequence listing; a short peptide of which the amino acid sequence is shown in sequence 3 in the sequence listing; and a short peptide of which the amino acid sequence is shown in sequence 4 in the sequence listing. Also provided are a conjugate containing the short peptide, a vaccine containing the conjugate and an application thereof. The vaccine containing the short peptide may significantly inhibit neointima in vascular restenosis mouse models and atherosclerosis in high-fat fed mice, and may be used to prevent or treat atherosclerosis and/or vascular restenosis.
Patent AU-2020359435-A1 (AU)
Title: Drug delivery device
Inventor: FINKELSTEIN EMIL
IPC: A61M5/32
Filed: 2020-09-29
Abstract: A drug delivery device may include a housing having an opening and a drug storage container having a body portion with a proximal end and a distal end and a delivery member extending from the distal end of the body portion. The device may also include a plunger moveable toward the distal end of the drug storage container to expel a drug from the drug storage container through the delivery member and a plunger biasing member configured to urge the plunger toward the distal end of the drug storage container. The device may further include a container holder configured to support the drug storage container with respect to the housing such that a resultant force acting on the drug storage container from the plunger biasing member is at least substantially completely borne by the distal end of the body portion of the drug storage container.
Patent AU-2020376052-A1 (AU)
Title: Methods and systems for menstrualome analysis
Inventor: Gire Stephen
IPC: C12Q1/6806
Filed: 2020-10-30
Abstract: Samples, systems for collecting samples, and methods of preserving samples from menstrual fluid are provided.
Patent AU-2020380721-A1 (AU)
Title: Droplet deformation-based method of transferring material into cells and chip for same
Inventor: CHUNG ARAM
IPC: B01L3/00
Filed: 2020-11-04
Abstract: Provided is a method of transferring a material into cells, comprising the steps of: forming droplets consisting of a material to be transferred and cells; and a step of subjecting the formed droplets to deformation, thereby transferring the material to be transferred, into the cells.
Patent AU-2020397926-A1 (AU)
Title: Method and system for self-aggregation of personal data and control thereof
Inventor: WILSHINSKY MURRAY B
IPC: G06F40/174
Filed: 2020-12-04
Abstract: A method includes receiving, by a logic layer processor, over a communication network, from a plurality of electronic resources, initial user personal identifiable information (PII) of a user of a plurality of users. The user PII includes a plurality of data elements. The plurality of data elements of the initial PII of the user are classified to populate a profile map data structure having a standardized predefined data schema of a plurality of vector elements so as to form a user-specific profile map data structure of the user. Additional user personal identifiable information (PII) of the user is iteratively received from the plurality of electronic resources. The additional user PII of the user is iteratively classified to update the user-specific profile map data structure of the user. A plurality of user-specific data management software functions is enabled based on the user-specific profile map data structure.
Patent AU-2020405356-A1 (AU)
Title: Microfluidic production of biofunctionalized giant unilamellar vesicles for targeted cargo delivery
Inventor: STAUFER OSKAR
IPC: B01L3/00
Filed: 2020-12-19
Abstract: The present invention relates to a method for preparation of monodisperse cell- targeting giant unilamellar vesicles based on symmetrically division of a parent polymer shell-stabilized giant unilamellar vesicle into smaller polymer shell- stabilized giant unilamellar vesicles with a diameter between 1 µm and 10 µm using a microfluidic splitting device. The inventive method allows preparation of differently charged giant unilamellar vesicles as well as bioligand- and PEG-conjugated giant unilamellar vesicles, which are useful for targeted cellular delivery at high efficiency and specificity. A further advantage of the present invention is that the giant unilamellar vesicles can deliver huge cargos such as drug releasing porous microparticles, high amounts of in vivo imaging probes, viruses, or up-and-coming DNA origami robots.
Patent AU-2020420912-A1 (AU)
Title: Frame folding mechanism, frame locking mechanism, backrest unlocking mechanism and stroller
Inventor: YUAN JIALIANG
IPC: B62B7/06
Filed: 2020-12-29
Abstract: The invention provides a frame folding mechanism (101), a frame locking mechanism (102), a backrest unlocking mechanism (103) and a stroller (100). A handle (11), a front foot (12), a seat portion (2) and a linking member (3) of the frame folding mechanism (101) form a planar linkage mechanism. The handle (11) and the front foot (12) can be driven to rotate and fold toward a rear foot (13), so as to drive the seat portion (2) to rotate and fold. The frame locking mechanism (102) can drive a sliding member (6) and a frame expansion locking member (7) to slide by an unlock driving mechanism (8), such that the frame expansion locking member (7) disengages from a handle locking hole (114) and a front foot locking hole (123) to unlock a frame (1). The backrest unlocking mechanism (103) has a backrest locking member (9). The unlock driving mechanism (8) can drive the backrest locking member (9) to slide, such that the backrest locking member (9) disengages from a backrest portion (4) to unlock the backrest portion (4).
Patent WO-2021168502-A1 (WO)
Inventor: WILSON ERIC
IPC: G06F16/93
Filed: 2021-03-01
Abstract: Data obtained from forms presented to end users, along with inventories, are together used by a computer system executing program logic. This produces reports by analyzing spatial form layout information and information types, and concatenating segmented product code tags according to end user interactions, to reduce custom programming of computer applications.
Patent WO-2022040758-A1 (WO)
Inventor: WAH JAMES HAMILTON
IPC: A61N1/36
Filed: 2021-08-30
Abstract: Controlling a neural stimulus comprises applying the neural stimulus to a neural pathway in order to give rise to an evoked action potential on the neural pathway, the stimulus being defined by at least one stimulus parameter. A neural compound action potential response evoked by the stimulus is measured, and from the measured evoked response a feedback variable is derived. Loop backoff behaviour is adjusted by applying a non-identity function to the feedback variable to produce a revised feedback variable, and completing a feedback loop by using the revised feedback variable to control the at least one stimulus parameter so as to maintain the feedback variable at a setpoint. Additionally, or alternatively, loop gain can be adjusted in response to a change in the loop setpoint, and/or a logarithm of the stimulus parameter can be controlled.
Patent WO-2022087662-A1 (WO)
Title: An anchor for a watercraft
Inventor: WEBSTER DUNCAN JOHN
IPC: B63B21/36
Filed: 2021-10-27
Abstract: An anchor for a watercraft comprising a shank and at least one prong adapted for attachment to the shank, wherein the anchor for a watercraft also comprises at least one weakened connection configured to release the at least one prong from the shank when a load on the at least one prong exceeds a predetermined threshold.
Patent WO-2022099376-A1 (WO)
Inventor: GOMEZ GUILLERMO A
IPC: C12M3/00
Filed: 2021-11-12
Abstract: There is a need to provide a system for culturing cells or cell clusters, such as organoids, whereby the location of the cell, or cell cluster, is fixed within the culture system. This permits easy localisation of an individual cell or cell cluster. Preferably, this is done in a manner that still allows for development of the cell or cell cluster in a biologically accurate way and can be readily used with high-throughput liquid handling techniques and analysis techniques, such as microscopy. This may be addressed by providing a cell culture insert, which provides a suspended cell growth platform which allows a cell, or cell cluster, to be cultured in an inverted position at a predetermined distance from the bottom of a cell culture plate.
Patent AU-2021203199-A1 (AU)
Title: Arteriotomy positioning device and method of use therefor
Inventor: DAILEY ERIC CHRISTOPHER
IPC: A61B17/00
Filed: 2021-05-18
Abstract: A method and device for positioning an expandable support in a blood vessel is 
disclosed herein. The device may include a handle, a catheter assembly, a core 
wire, and an expandable support. The expandable support may be used to position 
the device relative to the arteriotomy, as well as to provide temporary hemostasis.  
The expandable support may be attached to the catheter assembly at a first end, 
and to the core wire at a second end to optimize the width of the expandable support 
based on the function being performed by the expandable support at a given time.  
The catheter assembly may be able to move relative to the handle and the core wire, 
thereby moving the first end of the expandable support relative to the handle and the 
core wire.
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Patent AU-2021204192-A1 (AU)
Title: Systems, methods, and devices for securely managing network connections
Inventor: ARMSTRONG JAMES CALVIN
IPC: G06F21/50
Filed: 2021-06-21
Abstract: The disclosure relates generally to methods, systems, and apparatuses for managing 
network connections. A system for managing network connections includes a storage 
component, a decoding component, a rule manager component, and a notification component.  
The storage component is configured to store a list of expected connections for a plurality of 
networked machines, wherein each connection in the list of expected connections defines a start 
point and an end point for the connection. The decoding component is configured to decode 
messages from the plurality of networked machines indicating one or more connections for a 
corresponding machine. The rule manager component is configured to identify an unexpected 
presence or absence of a connection on at least one of the plurality of network machines based 
on the list of expected connections. The notification component is configured to provide a 
notification or indication of the unexpected presence or absence.
Patent AU-2021221602-A1 (AU)
Title: Suction liner and centrifugal pump comprising the same
Inventor: TUOMISALO AKI
IPC: F04D7/04
Filed: 2021-08-25
Abstract: A BLOCKING TOOL 
ABSTRACT 
A blocking tool and a method of using the blocking tool to sand a surface of a vehicle are 
disclosed. The blocking tool includes a first member having a length and having an outer 
periphery with a plurality of cuts formed therein. The plurality of cuts extend over at least about 
70% of the length and each of the cuts penetrates the first member through an arc of at least 
about 70% of the outer periphery. The blocking tool also has a base member with a first surface, 
an oppositely aligned second surface, and a length. A portion of the outer periphery of the first 
member is secured to the first surface of the base member to form an integral blocking tool.
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Patent AU-2021229245-A1 (AU)
Title: System with holder and piercing food thermometer, and holder
Inventor: SEYDEL LEON
IPC: G01K1/14
Filed: 2021-09-10
Abstract: The invention relates to a versatile system comprising a food thermometer (1) and a holder (2) 
for holding the food thermometer (1). The holder (2) comprises two different holding means (8, 
11, 15, 16) by which the food thermometer (1) can be held in two different holding positions.  
The invention also relates to a holder (2) for the system.
6/12 
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4 11 
15 10 
FIG. 10
Patent AU-2021240170-A1 (AU)
Title: Angle folded egress ladder
Inventor: WUBBEN THOMAS M
IPC: A01D41/12
Filed: 2021-09-29
Abstract: A ladder for an agricultural vehicle may comprise a first frame member and a second frame 
member. Each frame member may have an upper portion and a lower portion. At least one foot 
support body may be operably connected to each of the frame members. The upper portion of 
each frame member may be operably connected to a frame of the agricultural vehicle. The frame 
of the agricultural vehicle may comprise a fore and an aft. The ladder may comprise a deployed 
position and an angled stowed position. The angled stowed position may comprise the first 
frame member and the second frame member being upward and rearward towards the aft of the 
agricultural vehicle frame.  
(FIGURE 2 to accompany publication of abstract)
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140 
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154 
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154 
148 
154
Patent AU-2021261564-A1 (AU)
Title: Bone implant
Inventor: STOLINSKI ELVIRA
IPC: A61L27/32
Filed: 2021-04-23
Abstract: The invention relates to a bone implant (1) having a main part (10) in the form of a hollow body, which is open on both sides in an axial direction and which has or consists of a load-bearing material, and a casing body (20), which at least partly encases the exterior of the main part and has an in vivo degradable/in vivo resorbable material or consists of an in vivo degradable/in vivo resorbable material, or a plurality of molded bodies, which protrude from the main part in the radial direction and have an in vivo degradable/in vivo resorbable material or consist of an in vivo degradable/in vivo resorbable material. The invention additionally relates to a method for producing a bone implant. The method is characterized in that the bone implant is produced using an additive manufacturing method and/or a main part in the form of a hollow body, which is open on both sides in the axial direction and which has or consists of a load-bearing material, is at least partly encased by a casing body using the/an additive manufacturing method, said casing body having or consisting of an in vivo degradable/in vivo resorbable material, or is connected to a plurality of molded bodies, which have or consist of an in vivo degradable/in vivo resorbable material, such that the molded bodies protrude from the main part in the radial direction.
Patent AU-2021275042-A1 (AU)
Title: Systems and methods for controlling and maintaining the temperature of a drink within a drinking vessel
Inventor: PAWLIK RANDALL
IPC: A47G23/02
Filed: 2021-05-18
Abstract: Disclosed herein are systems for regulating a temperature of a drink, the system comprising: a receptacle system defining a recess for receiving a drinking vessel, including: an outer receptacle (1404), and an inner receptacle (1406) that is removably couplable to the outer receptacle, wherein a cavity is defined between the outer receptacle and the inner receptacle, the receptacle system comprising a top end portion, a bottom end portion, an inner wall portion, and an outer wall portion, the top end portion defines a top opening of the recess.
Patent AU-2021282444-A1 (AU)
Title: Uses of 4'-desferrithiocin analogs
Inventor: BERGERON RAYMOND J
IPC: A61K31/195
Filed: 2021-12-08
Abstract: Macular degeneration, closed head injury, stroke, irritable bowel disease, and 
reperfusion injury are all associated with biological injury due to reactive oxygen species, 
probably due to focal iron overload in many instances. The present invention provides 
methods and pharmaceutical compositions for treating these diseases and conditions using 
desferrithiocin analogs of Formula (I). In certain embodiments, the analogs include a 
polyether moiety at the 4'-position of the phenyl ring of the compound.  
R3 N R8 Rg 
5 
0 R7 
6 
(I)
Patent AU-2021291180-A1 (AU)
Title: Optical device for intraocular measurements
Inventor: ARIELI YOEL
IPC: A61F2/14
Filed: 2021-06-13
Abstract: Apparatus and methods are described including illumination equipment (300) configured to direct light into an eye of a subject. An optical device (100) is placed inside the subject's eye, the optical device including a Fabry Perot interferometer (106) comprising at least two mirrors (162, 164), the Fabry Perot interferometer (106) being configured such that a distance between the mirrors (162, 164) varies as an intraocular parameter of the subject's eye varies. A retroreflector (140) is configured such that light that is transmitted through the Fabry Perot interferometer (106) is automatically reflected out of the subject's eye. Readout equipment (400) is configured to detect the light that is reflected out of the subject's eye. Other applications are also described.
Patent AU-2021304467-A1 (AU)
Title: Fuel additives for mitigating injector nozzle fouling and reducing particulate emissions
Inventor: KUO CHUNG-HAO
IPC: C10L1/23
Filed: 2021-07-07
Abstract: The present disclosure provides a fuel composition that includes hydrocarbon-based fuel boiling in the gasoline or diesel range; an amine-based detergent given by formula R
Patent AU-2021327037-A1 (AU)
Title: Copper recovery method and apparatus
Inventor: HALLETT MICHAEL
IPC: F27D11/12
Filed: 2021-08-18
Abstract: An apparatus for recovering metal copper from a product material, comprising: a body having a central core formed therein and a coil mounted within the body and arranged to extend in a vertical axis so as to extend about the central core; a collecting crucible mounted beneath said core of the body for collecting metal copper from the product material; and a hoisting apparatus mounted with respect to the body, the hoisting apparatus being configured to lower the product material into the central core of the body and to suspend the product material therein; wherein, the coil is configured to receive a current to generate a magnetic field in the body such that the magnetic field generates eddy currents within the product material causing the product material to heat, thereby releasing the metal copper in a molten form from the product material into the collecting crucible for recovery.
Patent AU-2021334184-A1 (AU)
Title: Pesticidally active heterocyclic derivatives with sulfur containing substituents
Inventor: SIKERVAR VIKAS
IPC: C07D487/04
Filed: 2021-08-31
Abstract: Compounds of the formula (I) wherein G
Patent AU-2021336223-A1 (AU)
Title: Wireless power system with communications
Inventor: PATEL PARIN
IPC: H02J50/80
Filed: 2021-08-05
Abstract: A wireless power system may include an accessory configured to transfer or relay wireless power to a portable electronic device. The portable electronic device may include wireless charging circuitry and sensors configured to detect compatible accessories currently coupled with the portable electronic device. The portable electronic device performs wireless charging or related functions in accordance with the coupled accessories.
Patent AU-2021364397-A1 (AU)
Title: Forced air cooling for display assemblies
Inventor: DUNN WILLIAM
IPC: G02F1/133
Filed: 2021-10-22
Abstract: A display assembly with forced air cooling and integrated electric vehicle charging equipment includes a first and second side assembly connected to a structural frame, each including an electronic display subassembly located behind a cover. The electric vehicle charging equipment is connected to the structural frame between said first and second side assemblies in an at least partially recessed manner. Open or closed loops of air may be provided for cooling the first and second side assemblies and the electric vehicle charging equipment, which may all be connected to a common power source.
Patent AU-2021373282-A1 (AU)
Title: Method and apparatus for freezing or thawing mixtures comprising water
Inventor: CORVER JOZEF ANTONIUS WILLEM MARIA
IPC: F26B25/22
Filed: 2021-11-03
Abstract: The invention relates to a method for freezing injectable compositions, in particular pharmaceutical compositions. The method comprises: storing a quantity of a dispersion of an injectable composition in an aqueous dispersion medium in a vial; cooling the vial by applying cooling gas to the vial, the cooling characterized by performing at least one of (A), (B) and (C), wherein (A) is an initial cooling control scheme before nucleation has occurred in the dispersion layer, (B) is a crystallization control scheme during crystallization of the dispersion layer, and (C) is a final cooling control scheme after the dispersion layer has crystallized; and obtaining the dispersion after freezing is complete.
Patent AU-2021408090-A1 (AU)
Title: System and method for determining dosage of coffee grounds into a portafilter
Inventor: KONG TAE-KYUNG
IPC: A47J31/42
Filed: 2021-12-22
Abstract: A method of delivering coffee grounds into a portafilter fitted to a machine for grinding coffee including determining a pre-determined grind to provide the coffee grounds, applying a tamp to form the coffee grounds into a puck, and providing tamp position feedback to a user during and/or after a tamping operation. The invention also relates to a system for implementing the method.
Patent AU-2021411389-A1 (AU)
Title: Secure trimming of blockchain in a resource-constrained network
Inventor: WHITE ERIC
IPC: H04L9/00
Filed: 2021-09-30
Abstract: Based at least in part on a determination of an amount of remaining storage available in a device being relative to a particular level, a device trims at least a portion of the blockchain from the device including by making storage allocated to the portion of the blockchain available. The device recalculates the blockchain without the portion of the blockchain that has been trimmed from the device. Further, the device sends a message to another device participating in the blockchain, the message including at least the hash for the recalculated blockchain.
Patent AU-2021421161-A1 (AU)
Title: Ligand compounds, conjugates, and applications thereof
Inventor: ZHANG BILL BILIANG
IPC: A61P1/16
Filed: 2021-01-20
Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that comprise one or more ligand moieties for an asialoglycoprotein receptor (ASGPR). Exemplary chemical entities can further comprise an oligonucleotide. Said chemical entities are useful, e.g., in the targeted delivery of oligonucleotides to liver cells (e.g., liver parenchymal cells). The chemical entities are useful e.g., in the treatment of conditions or diseases caused by the expression (e.g., abnormal expression) of one or more genes in liver cells This disclosure also features compositions containing the same as well as methods of using and making the same.