baber/WOPTO huggingface dataset:
Patent CA-2185565-A1 (CA)
Title: Use of il-12 and il-12 antagonists in the treatment of autoimmune diseases
Inventor: LEONARD JOHN P
IPC: A61P37/00
Filed: 1995-03-07
Abstract: Method of treating autoimmune conditions are disclosed comprising administering to a mammalian subject IL.12 or an IL,12 antagonist. In certain preferred embodiments the autoimmune condition is one which is promoted by an increase in levels of IFN-.gamma. or TNF-.alpha.. Suitable conditions for treatment include multiple sclerosis systemic lupus erythematosus, rheumatoid arthritis, autoimmune pulmonary inflammation, Guillain-Barre syndrome, autoimmune thyroiditis, insulin dependent diabetes melitis and autoimmune inflammatory eye disease.
Patent CA-2185758-A1 (CA)
Inventor: STECKLY STEPHEN DALE
IPC: F17D5/02
Filed: 1996-09-17
Abstract: A method of stopping excessive leakage from sprinkler heads of a liquid piping network.   Firstly,  providing a backflow inducer housing divided by a flexible diaphragm into a first compartment on a first side of the diaphragm and a second compartment on a second side of the diaphragm.   The relative volume  of  the  first compartment  and the  second compartment change with the positioning of the diaphragm.  A spring is provided in the first compartment to bias the diaphragm toward a backflow inducing position in which the volume of the first compartment is larger than the volume of the  second  compartment.    Secondly,  connecting  a  first inlet/outlet of  the  housing to  a  liquid piping  network. Thirdly, connecting a second inlet/outlet of the housing to a source of pressurized working fluid.  The diaphragm is moved by the pressurized working fluid toward an operational position in which the volume of the second compartment is larger than the volume of the first compartment.   Fourthly, providing controls to exhaust the second compartment of the backflow inducer  housing  simultaneously  with  the  termination  of spraying.   The diaphragm is rapidly moved to the backflow inducing position thereby drawing sufficient liquid from the liquid piping system to prevent excessive leakage of the sprinkler heads.
Patent CA-2190270-A1 (CA)
Inventor: SOMMER GORDON M
IPC: B30B15/10
Filed: 1994-05-13
Abstract: A drive unit for driving a press is disclosed. The drive unit uses a hydraulically actuated oil shear brake unit (12) located on one side of a flywheel and a hydraulically actuated oil shear clutch unit (14) located on the opposite side of the flywheel. The actuation of the clutch (14) and the brake (12) occur simultaneously and from the same hydraulic pressure source such that there is no overlap between the two units (12,14).
Patent CA-2191274-A1 (CA)
Title: Calender for treating a web of paper
Inventor: KAYSER FRANZ
IPC: D21G1/00
Filed: 1996-11-26
Abstract: A calender for treating a web of paper includes a stack of hard rollers and soft rollers. The stack includes a first set of processing nips and a second set of processing nips. Each processing nip is formed by a juncture of one of the hard rollers and one of the soft rollers. One side of the web of paper contacts against the hard rollers in the first set of processing nips and contacts against the soft rollers in the second set of processing nips. At least a last soft roller in the stack, which delimits a last processing nip that the web of paper passes through in the calender, has a lower surface roughness Ra than a surface roughness Ra of at least a first soft roller in the stack. The first soft roller delimits a first processing nip that the web of paper passes through in the calender. The surface roughness Ra of the last soft roller is less than 0.35 µm.
Patent CA-2195302-A1 (CA)
Title: Carbon monoxide dependent guanylyl cyclase modifiers
Inventor: GLASKY ALVIN J
IPC: A61P25/28
Filed: 1995-07-25
Abstract: Disclosed herein are methods and associated compositions and medicaments directed generally to the control of cellular and neural activity and for selectively and controllably inducing the in vivo genetic expression of one or more naturally occurring genetically encoded molecules in mammals. More particularly, the present invention selectively activates or derepresses genes encoding for specific naturally occurring molecules such as proteins or neurotrophic factors and induces the endogenous production of such naturally occurring compounds through the administration of carbon monoxide dependent guanylyl cyclase modulating purine derivatives. The methods of the present invention may be used to affect a variety of cellular and neurological functions and activities and to therapeutically or prophylactically treat a wide variety of neurodegenerative, neurological, cellular, and physiological disorders.
Patent CA-2198648-A1 (CA)
Title: Method and device for cleaning cutlery
Inventor: HULSKOTTE JAN-HENDRIK
IPC: A22B3/10
Filed: 1995-08-29
Abstract: The invention concerns a cutlery cleaning device having a cleaning chamber and a spraying device which operates in said chamber. The cleaning chamber is disposed such that it can be removed from the cleaning device. The invention-further concerns a method of cleaning and disinfecting cutlery, the disinfecting and cleaning steps being carried out one after the other or vice versa in the same cleaning chamber.
Patent CA-2198919-A1 (CA)
Inventor: SMIT VICTOR
IPC: A61K48/00
Filed: 1995-08-30
Abstract: La présente invention concerne la modification graduelle spécifique de peptides et de protéines-signaux. En combinant la modification avec une localisation par traitement par protéase et de nouvelles formes de spectrométrie de masse, on obtient une modification tout à fait spécifique de la protéine ou du peptide. Ceci permet d'effectuer un changement souhaité dans l'activité biologique, de préférence d'obtenir une activité augmentée, une activité antagoniste et/ou une activité inhibitrice des cellules. L'activité antagoniste ou inhibitrice des cellules peut être obtenue par une modification chimique, en l'occurence une alkylation spécifique des groupes His qui se trouvent près ou sur le centre catalytique et/ou le centre de liaison de zinc de l'interleukine-3 humaine. On peut également utiliser cette invention pour générer des inhibiteurs et/ou des antagonistes, de préférence par des modifications biologiques au niveau moléculaire, des modifications chimiques et/ou des alkylations, de préférence par l'iodo-acétate. De préférence, ces modifications sont dirigées contre les groupes His, d'autres groupes catalytiques et/ou des groupes de liaison de zinc. Les résultats et les informations additionnelles obtenues indiquent que l'invention peut également être facilement appliquée à d'autres substances signal. Les produits peuvent également être utilisés pour réaliser des ADN de recombinaison et servir en thérapie génique. L'invention couvre les procédés présentés, les substances obtenues et leur utilisation.
Patent CA-2199276-A1 (CA)
Title: Protective cover for electrical connectors
Inventor: LA SALVIA JOSE ALEXANDRE
IPC: H01R13/52
Filed: 1995-07-20
Abstract: A protective cover assembly (10) for electrical connectors is disclosed having a cover (20) with body cable passages (50). A spacer latch component (60) is operatively disposed in the passages (50) for latching electrical cables (12, 14) to the assembly (10). Sealant grease (46) is disposed in a channel (44) of the body (40) for sealing between the cover (20) and the body (40). Sealing and dielectric compound pads (59a, 59b) are disposed adjacent to the spacer latch component (60) and body cable passage (50). The protective cover assembly (10) thus provides protection against moisture and other contaminants which would tend to cause corrosion and failure of the electrical connector.
Patent CA-2199548-A1 (CA)
Inventor: ROSS DOUGLAS A
IPC: G03G15/23
Filed: 1997-03-10
Abstract: In a simplex or duplex copier with plural different document inputs, including at least one input normally used for copying single documents and another normally used for copying plural documents, a system is provided for automatically selecting duplex copying whenever appropriate, to save copy sheets, including a controller programmed to automatically select between simplex or duplex copying and to direct the copy sheets into a duplex copying path when duplex copying is selected, and respective document input sensors connected to provide control signals to the controller upon sensing a document at a respective document input, the controller automatically selecting duplex copying unless there is a signal from a document input sensor at a document input normally used for copying single documents, such as a semi-automatic document input or a sensor sensing the lifting of the document handler, or, even though the document input normally used for copying plural documents is the input tray of an automatic recirculating document handler unit, a downstream sensor detects that only a single document was fed from that tray to be copied.
Patent CA-2200596-A1 (CA)
Title: Cable splice closure
Inventor: WAMBEKE ALAIN
IPC: H02G15/013
Filed: 1995-09-19
Abstract: A cable splice closure is disclosed, which comprises a casing (29) which, in use, is closed around a cable splice (21); and at least one cable gripper comprising a strip (25) which, in use, is wound around at least one cable (23) extending into the casing (29). Closing the casing (29), in use, automatically causes the or each strip (25) to tighten around the or each cable around which it is wound, thereby gripping the cable (23). The cable gripper strip (25) may have the ability to decrease in length when wound and compressed around a cable (23), thereby allowing it to contract, and therefore tighten, around the cable (23).
Patent CA-2204636-A1 (CA)
Title: Diagnostic method and kit for determining kell blood group genotype
Inventor: LEE SOOHEE
IPC: C12Q1/68
Filed: 1995-11-09
Abstract: The invention provides a diagnostic method of determining Kell genotype by the identification of the molecular basis of a Kell polymorphism. Specifically, the invention provides a method for determining K1/K2 genotype with great accuracy, overcoming problems associated with traditional serological typing methods. The diagnostic method of the invention preferably employs amplification of K1/K2 nucleic acid sequences, and optionally employs differential cleavage of K1-K2-specific nucleic acid sequences by a restriction enzyme. Also provided are nucleic acid oligomers useful as probes or primers for the method of the invention. Furthermore, diagnostic kits for the determination of Kell genotype are provided.
Patent CA-2205239-A1 (CA)
Title: Rim elastomers based on prepolymers of cycloaliphatic diisocyanates
Inventor: STEPPAN DAVID D
IPC: C08G18/28
Filed: 1997-05-13
Abstract: This invention relates to a process for the production of polyurethane/urea elastomers from a reaction injection molding process of a reaction mixture on the presence of a catalyst via the one-shot process. The isocyanate component of this invention is a prepolymer based on a cycloaliphatic diisocyanate, and having an NCO content of 12-27%, an average isocyanate functionality of less than 2.3, a monomer content of greater than about 25% by weight, and containing urethane or urea groups. The isocyanate-reactive blend comprises a high molecular weight polyether polyol and a low molecular weight chain extender wherein the equivalent ratio of hydroxyl groups to amine groups of the chain extender is from 1:2 to 20:1. This invention also relates to the polyurethane/urea molded article produced by the above process.
Patent CA-2205323-A1 (CA)
Title: Safety disconnection with asymmetric lamp power
Inventor: FRANCK FELIX
IPC: H05B41/295
Filed: 1997-05-14
Abstract: A circuit is proposed for the AC voltage operation of a discharge lamp by means of a coupling capacitor (C3) with a safety disconnection device, connected in series with the lamp for DC current separation, which is characterized by the fact that the safety disconnection device responds to a DC voltage (UC3) at coupling capacitor (C3) by means of a DC current component flowing through the lamp.
Patent CA-2205564-A1 (CA)
Inventor: KEEFER LARRY K
IPC: A61K47/48
Filed: 1995-11-20
Abstract: A polymeric composition capable of releasing nitric oxide under physiological conditions which includes a biopolymer, such as a peptide, polypeptide, protein, oligonucleotide or nucleic acid, to which is bound a nitric oxide-releasing N2O2- functional group; pharmaceutical compositions comprising the polymeric composition; and method of treating biological disorders in which dosage with nitric oxide is therapeutic.
Patent CA-2206147-A1 (CA)
Title: Medical device with biomolecule-coated surface graft matrix
Inventor: HENDRIKS MARC
IPC: A61L33/00
Filed: 1997-05-26
Abstract: A medical device having a surface graft matrix comprising carboxyl-functional groups located on the device, the surface graft matrix comprising an outer portion; and one or more biomolecules covalently coupled to the surface graft matrix, wherein a majority of the biomolecules are located in the outer portion of the surface graft matrix. The surface graft matrix can also be loaded with a pharmaceutical agent.
Patent CA-2208514-A1 (CA)
Title: Applicator for flowable materials
Inventor: WHITE ROBERT ASHTON
IPC: B43K23/12
Filed: 1995-12-21
Abstract: The present invention relates to an applicator (100) for flowable materials which comprises a generally cylindrical housing (2) having a chamber, a discharge opening, a wick (12) projecting through said discharge opening, and a projecting structure (6) for shielding the user from flowable materials and for preventing placement of the applicator (100) in inappropriate receptacles. Further, the present invention relates to a storage and shipping rack for said applicators and to a method of dispensing flowable materials onto a surface. Preferably, the applicator (100) is filled with metal coating and treating compositions such as aqueous acidic chromate compositions. Most preferably, the acidic compositions contain a very low concentration of a fluorinated surfactant.
Patent CA-2210461-A1 (CA)
Inventor: LE MANCHEC VINCENT
IPC: A47H15/04
Filed: 1996-01-08
Abstract: PCT No. PCT/FR96/00024 Sec. 371 Date Jul. 2, 1997 Sec. 102(e) Date Jul. 2, 1997 PCT Filed Jan. 8, 1996 PCT Pub. No. WO96/21381 PCT Pub. Date Jul. 18, 1996A window curtain hanging device constituted by a plastics material strip whose two ends are for fixing to the top of a curtain and whose central portion (3, 3a) matches the shape of a curtain rod, the strip serving as a support for a decorative tab.
Patent CA-2211300-A1 (CA)
Inventor: BONETT HEATHER ELIZABETH
IPC: C11D3/02
Filed: 1996-01-12
Abstract: A process for bleaching and/or providing limescale removal at a surface, comprising applying to that surface an aqueous composition of hydrogen peroxide or an organic peracid, which composition has a pH of 2 or less and comprises a mixture of (a) an aqueous composition comprising hydrogen peroxide or an organic peracid having a pH of greater than 2 but less than 7 (hereinafter component (a)), and (b) an acidic composition (hereinafter component (b)), wherein components (a) and (b) are mixed not more than two hours before being applied to the surface requiring bleaching and/or limescale removal.
Patent CA-2211734-A1 (CA)
Inventor: TROKHAN PAUL DENNIS
IPC: D21H17/06
Filed: 1996-01-26
Abstract: Papier de soie ayant une douceur de parties à haute densité de volume améliorée comprenant entre 0,01 et 5 % d'un composé polyhydroxylé soluble dans l'eau, par exemple du glycérol, sur la base du poids des fibres sèches du papier. Ces composés polyhydroxylés non ioniques présentent des taux élevés de rétention lorsqu'ils sont appliqués (120) sur la feuille continue de papier de soie (88) obtenue par voie humide, à une densité de fibres comprise entre 10 et 80 %, sur une machine à papier (80), avant le séchage (100, 108, 110) et le crêpage (111) de la feuille continue. Le papier de soie peut également comprendre des additifs, tels que l'amidon, pour en renforcer la résistance.
Patent CA-2220447-A1 (CA)
Title: Novel fusion protein recovery and purification methods
Inventor: WINTERS DWIGHT
IPC: C07K1/30
Filed: 1996-04-11
Abstract: Provided by the present invention are novel methods of protein recovery and purification methods and more specifically novel methods for the recovery and purification thioredoxin fusion proteins, especially of
Patent CA-2225678-A1 (CA)
Title: Cleaning/sanitizing methods, and/or articles for edible animal protein
Inventor: BAKER KEITH HOMER
IPC: A23L1/00
Filed: 1996-06-27
Abstract: Basic cleaning compositions methods using toxicologically-acceptable ingredients for cleaning edible animal protein are provided. Liquid formulations comprising detergent surfactant, such as oleate, alcohol ethoxylates, etc., and alkaline buffer are sprayed onto meat, seafood, poultry and the like to remove soil and unwanted deposits. Articles for applying the compositions to edible animal protein by spraying are disclosed. Use of the compositions for disinfectancy/sanitization of edible animal protein and mitigation of malodor are disclosed.
Patent CA-2226451-A1 (CA)
Title: Hidden surface laser shock processing
Inventor: WALTERS CRAIG T
IPC: B23K26/06
Filed: 1998-01-07
Abstract: The invention includes a laser processing method for processing a hidden surface of a workpiece, the hidden surface disposed within a recess having an opening. The method comprises inserting a reflective member into the recess and directing a pulse of coherent energy to reflect off of said reflective member and impact the hidden surface of workpiece to create a shock wave. Alteratively a surface of the recess may be modified to laser shock process the hidden surface.
Patent CA-2230559-A1 (CA)
Inventor: HELMST DTER MAXIMILIAM
IPC: B65H3/06
Filed: 1997-02-13
Abstract: A stacked-sheet prefeeder comprises a sheet guiding device for receiving therein a stack of sheets, an intermediate try, a scale former for removing sheets, arranged in a stack and/or in a scalelike mode of arrangement, jointly from the lower surface of the stack received in the sheet guiding device and for introducing these sheets into the intermediate tray in a first direction of movement, a sheet separator for removing from the intermediate tray the respective lowermost sheet as a single sheet in a second direction of movement which is substantially opposed to the first direction of movement, and a guide means arranged in the intermediate tray and used for guiding the sheets in the intermediate tray at their sheet edges constituting the front sheet edges in the second direction of movement, the guide means being implemented as a transport guide means in such a way that it moves the sheet edges in the second direction of movement in the interior of the intermediate tray to the sheet separator in effect the passive slide guide of prior art devices is replaced with an active guide comprising a section of the bottom feed conveyor belt
Patent CA-2234310-A1 (CA)
Inventor: ABU-ULBA SHERRI-LYNN
IPC: A47K7/02
Filed: 1998-06-01
Abstract: This invention relates to a means of providing personal foot hygiene for all ages of people, in particular taking advantage of the normal time that a person is in the bath tub or shower. By providing a device which acts as a abrading device and a cleansing brush at the same time stabilizes the user and applies soaps and conditioners to aid in proper foot care. The device incorporates self attaching, self cleansing action as well as portability and storage hanger mount. Replacable abrasion and brush surfaces and a specially contoured massaging roller high light this novel invention, as does the unique ability to personalize the base unit to as many persons as may wish to use it
Patent CA-2235300-A1 (CA)
Inventor: KRINGS FRANK
IPC: B60K15/04
Filed: 1998-04-20
Abstract: A motor  vehicle  tank  has  a filler pipe  including a portion which is elastically deformable at least over a part of its periphery and  which is  such that  in  an unexpanded condition  it represents  a constriction  in  the  filler  pipe.  The  constriction can be at  least reduced by elastic expansion of the elastically deformable portion in dependence on the amount of fuel flowing through the filler pipe. The filler pipe may extend into the interior of the tank.
Patent CA-2238440-A1 (CA)
Title: High temperature, high speed rotary valve
Inventor: GILES PAUL ALLAN
IPC: F04D23/00
Filed: 1996-11-21
Abstract: There is provided a high speed rotary valve which is relatively simple in design and which can effectively regulate the flow of fluid under high temperature conditions in such a manner as to produce perturbations in the fluid stream.  Such a valve may be used to regulate the flow of fluid, e.g. air, toward a work piece to produce a perturbation in the piece for example. The clearance between the rotor and stator is such that the flow of fluid is never completely cut off, i.e., the valve continues to "leak through" the closed outlet port even when the rotor and stator openings are not aligned. Fluids having temperatures in the range of 40 to at least 900 °F may be processed through this valve. The valve is also useful in creating aerosols of liquids and gases and in producing blown fibers.
Patent CA-2238845-A1 (CA)
Title: Novel 2,3,5-trimethyl-4-hydroxy anilide derivatives, preparation thereof and therapeutical use thereof
Inventor: OMS PHILIPPE
IPC: C07C323/60
Filed: 1996-11-27
Abstract: PCT No. PCT/FR96/01877 Sec. 371 Date May 27, 1998 Sec. 102(e) Date May 27, 1998 PCT Filed Nov. 27, 1996 PCT Pub. No. WO97/19918 PCT Pub. Date Jun. 5, 1997Novel 2,3,5-trimethyl-4-hydroxyanilide derivatives of general formula I, wherein, e.g., R1 is phenyl, R2 is H, R3 is C12H25, and A is a sulphur atom, are disclosed. A method for preparing said derivatives, pharmaceutical compositions containing at least one of said compounds as active principle, and the use of such derivatives for treating hypercholesterolemia or atherosclerosis.
Patent CA-2238898-A1 (CA)
Inventor: NEWMAN ROBERT L
IPC: G01N33/00
Filed: 1998-05-26
Abstract: A gas sensor for being placed into a gas stream. The sensor includes 1) a base having an axis that is perpendicular to the gas stream, 2) a sensor element on the base, 3) a catalyzed sensor element on the base proximate the sensor element, for creating an exothermic reaction upon contacting the gas stream thereby forming a heated gas stream portion, and 4) the catalyzed sensor element and the sensor element are positioned on the base so that as the base rotates about the axis, the heated gas stream portion will not contact the sensor element. In particular, the base has a second axis being perpendicular to the axis and separating the sensor element from the catalyzed sensor element. Additionally, the invention provides a device that may have both the sensor element and the catalyzed sensor element including a longitudinal axis. Wherein, both the sensor element and the catalyzed sensor element may have many different shapes. Both the sensor element and the catalyzed sensor element may have two or three sides that are coextensive with at least one void. As a result of having a void the base may include a bridge that connects at least one side of the sensor element and the catalyzed sensor element to the base.
Patent CA-2238905-A1 (CA)
Title: Transmission signal id for analog television broadcasts
Inventor: EYER MARK K
IPC: H04N21/482
Filed: 1998-05-26
Abstract: A received analog television service is positively identified using a transmission signal identifier that is inserted into the analog signal at the transmitter side, and extracted at the receiver side. Channel map data which is used for identifying counterpart digital programming services is extended to encompass identification of the analog services.      Descriptive information which is specific to the programming services, such as program guide data, can thereby be accurately matched up and displayed with a received analog programming service.