baber/WOPTO huggingface dataset:
Patent CA-3022758-A1 (CA)
Title: Treatment of skin lesions
Inventor: FABBRO DORIANO
IPC: A61K31/5377
Filed: 2017-05-17
Abstract: The present invention is relates to a compound of formula (I), wherein X1, X2 and X3 are, independently of each other, N or CH; with the proviso that at least two of X1 X2 and X3 are N; Y is N or CH; W is H or F; with the proviso that when W is F, then X1, X2 and X3 are N; R1 and R2 are independently of each other (i) a morpholinyl of formula (II) wherein the arrow denotes the bond in formula (I); and wherein R3 and R4 are independently of each other H, C1-C3alkyl optionally substituted with one or two OH, C1-C2fluoroalkyl, C1-C2alkoxy, C1alkoxyC1-C3alkyl, CN, or C(O)O-C1-C2alkyl; or R3 and R4 form together a bivalent residue -R5R6- selected from C1-C3alkylene optionally substituted with 1 to 4 F, -CH2-O-CH2-, -CH2-NH-CH2-, or any of the structures wherein the arrows denote the bonds in formula (II); or (ii) a saturated 6-membered heterocyclic ring Z selected from thiomorpholinyl and piperazinyl, optionally substituted by 1 to 3 R7; wherein R7 is independently at each occurrence C1-C3alkyl optionally substituted with one or two OH, C1-C2fluoroalkyl, C1-C2alkoxyC1-C3alkyl, C3-C6cycloalkyl; or two R7 substituents form together a bivalent residue-R8R9- selected from Ci-C3alkylene optionally substituted with 1 to 4 F, -CH2-O-CH2- or -O-CH2CH2-O-; with the proviso that at least one of R1 and R2 is a morpholinyl of formula II; and prodrugs, metabolites, tautomers, solvates and pharmaceutically acceptable salts thereof, for use in the prevention or treatment of a skin lesion in a subject.
Patent CA-3023447-A1 (CA)
Title: Garments
IPC: A41C3/00
Filed: 2018-11-08
Abstract: A garment comprising a support structure adapted to support breasts of a wearer; a first engagement feature coupled to an outer edge of the support structure on a first lateral side of the wearer and adapted to extend to a shoulder on a second lateral side of the wearer;  a second engagement feature coupled to an outer edge of the support structure on a second lateral side of the wearer and adapted to extend to a shoulder on a first lateral side of the wearer, wherein, as viewed in-use, a vertical line extending along a back of the wearer intersects only the first and second engagement features, and wherein the first and second engagement features lie along best fit lines that intersect one another.
Patent CA-3023548-A1 (CA)
Inventor: SIMARD JO-ANNE
IPC: B26B1/02
Filed: 2018-11-08
Abstract: A food cutting utensil particularly adapted for cutting, preferably, a fruit or vegetable having a substantially hard skin. The food cutting utensil comprises a first and a second knife element each including a handle portion and a blade portion extending longitudinally distally from one end of the handle portion and terminating in a pointed end. The first and second knife elements are each pivotally connected to one another via a pivot pin element extending transversally through their respective pointed end. When both knife elements are longitudinally parallel relative to one another, their cooperatively pointed ends may be penetrated into the fruit or vegetable to be cut, followed with pivoting at least one of the knife elements relative to the other so as to cut the fruit or vegetable.
Patent CA-3023671-A1 (CA)
Inventor: ASCHENBECK DAVID P
IPC: E04D5/00
Filed: 2017-05-04
Abstract: An exemplary shingle includes at least one coated shingle sheet defining a headlap portion and a tab portion each having opposed upper and lower surfaces. A first line of adhesive is adhered to one of the upper surface of the headlap portion and the lower surface of the tab portion, and includes a first thermally activated adhesive material. A second line of adhesive is adhered to one of the upper surface of the headlap portion and the lower surface of the tab portion, and includes a second thermally activated adhesive material having a minimum activation temperature less than a minimum activation temperature of the first thermally activated adhesive material.
Patent CA-3024775-A1 (CA)
Inventor: ROSEN PER
IPC: F24D10/00
Filed: 2017-06-29
Abstract: The invention refers to a combined cooling and heating system (100) comprising: a district cooling grid (1) having a feed conduit (5) for an incoming flow of cooling fluid having a first temperature, and a return conduit (8) for a return flow of cooling fluid having a second temperature, the second temperature being higher than the first temperature; a local cooling system (300) being configured to absorb heat from a first building (2) and comprising a heat exchanger (9) having a heat exchanger inlet (14a) and a heat exchanger outlet (14b); and a local heating system (200) being configured to heat the first or a second building (2) and comprising a heat pump (10) having a heat pump inlet (15a) and a heat pump outlet (15b). The heat exchanger inlet (14a) is connected to the feed conduit (5) of the district cooling grid (1); and the heat pump inlet (15a) is connected to the return conduit (8) of the district cooling grid (1) and to the heat exchanger outlet (14b).
Patent CA-3027284-A1 (CA)
Inventor: YANG SUCKCHEL
IPC: H04W72/12
Filed: 2017-06-15
Abstract: The present invention relates to a wireless communication system, more specifically to a method and an apparatus therefor, the method comprising the steps of: merging a first cell having a first TTI and a second cell having a second TTI, the length of the second TTI being N (N > 1) times the length of the first TTI; receiving data scheduling information for the second cell in the first TTI of the first cell; and establishing data communication on the basis of the data scheduling information in the second TTI of the second cell corresponding to the first TTI of the first cell, wherein the first TTI for the first cell is any one TTI from among the N number of TTIs of the first cell corresponding to the second TTI of the second cell.
Patent CA-3029238-A1 (CA)
Title: Dispositif de protection auditive presentant des detecteurs de position et de surveillance du son destines a eviter les risques proactifs lies au son
Inventor: AWISZUS STEVEN T
IPC: A42B3/16
Filed: 2017-06-23
Abstract: La présente invention dans certains exemples, présente un système (1900) comprenant un dispositif de protection auditive (1920) ; au moins un détecteur de position ; au moins un détecteur de surveillance du son ; au moins un dispositif informatique configuré pour : recevoir, à partir dudit détecteur de surveillance du son et sur une durée de temps, des indications des niveaux de son auxquels est exposé un travailleur ; déterminer, à partir dudit détecteur de position et sur la période de temps, que le dispositif de protection auditive n'est pas positionné au niveau d'une ou plusieurs oreilles du travailleur pour atténuer les niveaux de son ; et générer, en réponse à la détermination qu'au moins l'un des niveaux de son satisfait un seuil d'exposition sur la durée de temps et que le dispositif de protection auditive n'est pas positionné au niveau d'une ou plusieurs oreilles du travailleur pour atténuer les niveaux de son, une indication d'émission.
Patent CA-3034030-A1 (CA)
Inventor: LIODDEN DAG OEYVIND
IPC: G06Q30/00
Filed: 2016-09-01
Abstract: A system and method is provided to track users across applications and devices, and to distinguish similar or different users among a number of commonly-used devices. Accordingly, systems and methods are provided for analyzing user device information to determine different users among a number of devices. In particular, user's behavior when using the devices is observed, and responsive to that observed behavior, is the determined whether a particular users are distinguishable from other users. For instance, it may be useful to distinguish between users that operate the same devices or exist within a similar network (e.g., a home network, a workplace network, etc.) for various purposes. For instance, it may be useful to distinguish between users for displaying advertising to these users, performing some other operation with respect to a subset of the users.
Patent CA-3034649-A1 (CA)
Title: Procedes de detection de changements de copie genomique dans des echantillons d'adn
Inventor: RAYMOND CHRISTOPHER K
IPC: C12Q1/68
Filed: 2017-08-24
Abstract: La présente invention comprend des compositions et des procédés utiles à la détection d'un changement mutationnel, de SNP, de translocation, d'inversion, de délétion, de changement dans le nombre de copies, ou d'autre variation génétique à l'intérieur d'un échantillon d'ADN génomique cellulaire ou d'ADN acellulaire (ADNsc). Dans certains modes de réalisation, les compositions et les procédés de la présente invention fournissent un niveau extrêmement élevé de résolution qui est particulièrement utile dans la détection des variations du nombre de copies en une petite fraction de l'ADN acellulaire total à partir d'un échantillon biologique (par exemple, le sang).
Patent CA-3038113-A1 (CA)
Inventor: KATOU SEIYA
IPC: B60R21/00
Filed: 2017-08-01
Abstract: The purpose of the present invention is to provide a safe driving assistance technology which efficaciously reduces collisions regardless of environment or vehicle type. This safe driving assistance device 200 comprises: a connection destination detection unit 259 which detects and manages a connection state between the device and a connection destination device which is either a user interface 133 or an operation management terminal 112; a unique information setting unit 251 which, according to the connection destination device, sets unique information which identifies a type of a host vehicle; a position information acquisition unit 257 which acquires position information of the host vehicle; a host vehicle information management unit 252 which manages host vehicle information which includes the position information and unique information of the host vehicle; a vehicle-to-vehicle communication unit 255 which, by carrying out a communication with a safe driving assistance device which is mounted upon another vehicle, transmits the host vehicle information to the other vehicle and acquires other vehicle information; a risk assessment unit 254 which, using the host vehicle information and the other vehicle information, assesses whether a risk of collision exists between the host vehicle and the other vehicle; and output units 258, 256, 260 which output a result of the assessment.
Patent CA-3038752-A1 (CA)
Title: Empiecement de rallonge pour vetement de compression
Inventor: MARKWALD HOLLI
IPC: A41C3/12
Filed: 2019-04-02
Abstract: Il est décrit un vêtement de support à porter à la suite d'une procédure chirurgicale. Le vêtement a une fermeture avant pour permettre au porteur ou à la porteuse du vêtement de mettre et d'enlever le vêtement sans aide. Un empiècement de rallonge fournit un calibrage et une détermination de la forme du vêtement afin d'améliorer le confort et d'accroître l'efficacité du vêtement lors de sa portée.
Patent CA-3039860-A1 (CA)
Inventor: UCELLI MAURO
IPC: H03F3/217
Filed: 2017-10-18
Abstract: An electronic driving circuit (20) for a microfluidic device (1), having a number of synchronized driving stages (22) to generate a respective driving signal (Vi,V2,V3) for each electrode or group of electrodes (4,6) of the microfluidic device, the driving signals having a desired amplitude, frequency and phase-shift. Each driving stage has a switching-mode amplifier stage (22) to receive a clock signal (CK) and a target signal (Vt) and to generate, at an output (Out) thereof, an output signal (Vout) defining a respective driving signal. The amplifier stage has: a switching module (23), coupled to a first internal node (N1) and controlled by the clock signal for selectively bringing the first internal node (N1) to a control signal (Vc); a filter module (25,26), coupled between the first internal node and the output, to provide the output signal; and a feedback module (29).
Patent CA-3046666-A1 (CA)
Inventor: LI JINAN
IPC: A61P17/00
Filed: 2017-06-19
Abstract: L'invention concerne une méthode de prévention et de traitement de fibrose de tissu et d'organe, comprenant l'administration d'une quantité efficace de plasminogène à un sujet.
Patent CA-3047286-A1 (CA)
Inventor: ALLEN JENNIFER R
IPC: C07D413/10
Filed: 2017-12-13
Abstract: The present disclosure provides a class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula I: (insert Formula I structure) wherein variables W, X, Y, R2, R2', R3, R4, R5, R6, and R7 of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, and uses of the compounds and compositions for treatment of disorders and/or conditions related to beta amyloid (Aß) plaque formation and deposition, resulting from the biological activity of BACE. Such BACE mediated disorders include, for example, Alzheimer's Disease, cognitive deficits, cognitive impairments, and other central nervous system conditions.
Patent CA-3047327-A1 (CA)
Inventor: SPIRO STEVEN M
IPC: B25B11/02
Filed: 2017-12-20
Abstract: A spline installation device for use with a spline/rail type frame to assemble the splines to the rails. The device including a base that defines a platform for receiving a frame subassembly; and a plurality of linkages that are disposed about the platform and coupled to the base. Each linkage is configured to move between a first position in which a fence bearing surface thereof is at an angle other than 90 degrees relative to the platform and a second position in which the fence bearing surface is set at an at least substantially 90 degree angle relative to the platform for locking and holding the frame subassembly in place. The linkages further being configured to receive a spline instillation tool for locking the splines in place relative to the rails.
Patent CA-3051558-A1 (CA)
Title: System and method for speech-based interaction resolution
Inventor: SAINI RANJEET
IPC: G10L17/22
Filed: 2018-01-30
Abstract: A method for automatically retrieving documents based on customer speech received at a contact center of an organization includes: receiving, by a processor, at the contact center of the organization, speech from a customer; performing, by the processor, automatic speech recognition on the received speech to generate recognized text; generating, by the processor, a search query from the recognized text; searching, by the processor, a knowledge base specific to the organization for one or more documents relevant to the search query; and returning, by the processor, the one or more documents relevant to the search query.
Patent CA-3051789-A1 (CA)
Title: Pharmaceutical active ingredient and use thereof, in particular for the prevention and treatment of metabolic disorders in humans and animals
Inventor: PELTIER SEBASTIEN
IPC: A61P3/10
Filed: 2018-02-13
Abstract: The subject matter of the invention is a pharmaceutical active ingredient consisting exclusively of the combination of (lS,3R,4R,5R)-3-{[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]oxy}-1,4,5-trihydroxycyclohexanecarboxylic acid and methyl (2S,3E,4S)-4-{2-[2-(3,4- dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-(P-D-glucopyranosyloxy)-3,4-dihydro-2H-pyran-5-carboxylate for use as a medicine or veterinary product, in particular in the prevention and/or treatment of pathological carbohydrate and/or lipid metabolism disorders.
Patent CA-3057632-A1 (CA)
Inventor: YOUNG WEI-TAI
IPC: B01D61/00
Filed: 2018-03-22
Abstract: La présente invention concerne des procédés de réduction de molécules physiologiques dans des taux anormaux et/ou des toxines exogènes dans le sang à partir du sang au moyen d'un circuit extracorporel comprenant un module de filtre à fibres creuses et un sorbant polymère associé.
Patent CA-3058060-A1 (CA)
Inventor: DRESSLER MARTIN
IPC: B02C18/18
Filed: 2019-10-09
Abstract: The invention relates to the use of a knife (1) for processing wet wood and/or raw wood.  The knife comprises a knife base body (2) and at least one cutting plate (3) with a cutting edge (4), the cutting plate (3) being carried by the knife base body (2). The cutting plate (3) is fixed on the blade body (2) by means of a brazed joint (5) with a copper solder (6).
Patent CA-3058592-A1 (CA)
Title: Olanexidine as anti-inflammatory agent
Inventor: NII TAKUYA
IPC: A61P11/00
Filed: 2018-04-10
Abstract: The present invention addresses the problem of providing a composition which is usable as a novel anti-inflammatory agent. Inflammation such as stomatitis, oral mucositis, gingivitis and pneumonia can be ameliorated and/or prevented by using a composition which comprises olanexidine or a pharmacologically acceptable salt thereof. Preferably, the composition according to the present invention further comprises a poloxamer which is a block copolymer comprising a polyoxypropylene (POP) chain sandwiched between two polyoxyethylene (POE) chains.
Patent CA-3061373-A1 (CA)
Title: Pod mobile de realite virtuelle
Inventor: SCHWARTZ JUSTIN MICHAEL
IPC: A63G31/16
Filed: 2018-05-07
Abstract: Selon un mode de réalisation, un système comprend un système d'attraction de réalité virtuelle. Le système d'attraction de réalité virtuelle comprend un casque de réalité virtuelle (VR) et/ou de réalité augmentée (AR) configuré pour afficher des images AR et/ou des images VR à l'attention d'un utilisateur, ainsi qu'au moins un véhicule assisté par utilisateur configuré pour recevoir l'utilisateur. Le véhicule comprend un cadre configuré pour permettre à l'utilisateur de fournir au moins une puissance moteur partielle afin de déplacer le véhicule au sein de l'attraction. Le cadre définit une limite autour de l'utilisateur. Le véhicule comprend également un harnais couplé au cadre et configuré pour fournir un support à l'utilisateur lorsque l'utilisateur se trouve dans le véhicule, ainsi qu'un dispositif de commande de véhicule configuré pour communiquer les images AR et/ou VR au casque de réalité virtuelle (VR) et/ou de réalité augmentée (AR).
Patent CA-3063360-A1 (CA)
Inventor: SHARMA GAURAV
IPC: H04L29/06
Filed: 2018-05-11
Abstract: Nos noms dans le monde physique et réel sont transformés en « noms d'utilisateur » dans le monde numérique virtuel. Tout ce auquel nous devons accéder dans le monde numérique nous demande un « nom d'utilisateur », qui peut être sélectionné par l'utilisateur (comme une adresse de courrier électronique) ou fourni à un utilisateur (comme un identifiant/numéro d'employé). Ledit « nom d'utilisateur » est en effet devenu un supernom, donnant accès à des zones restreintes, sur la base de privilèges, de liens vers d'autres services ainsi que d'autres services. Ainsi, pour un cybercriminel, si un « nom d'utilisateur » est connu, plus de la moitié de la tâche est faite. Et une fois que le mot de passe correspondant est craqué, l'intégralité de l'identité numérique ne tient plus qu'à un fil. Les dommages effectués par l'intermédiaire de transactions d'un tel accès non autorisé peuvent être quantifiés, mais le respect de la vie privée est beaucoup plus dommageable.
Patent CA-3064785-A1 (CA)
Title: Epitopes in the rna recognition motif 1 (rrm1) of tdp-43 and misfolding-selective antibodies thereto
Inventor: PLOTKIN STEVEN SAMUEL
IPC: A61K39/39
Filed: 2018-05-30
Abstract: The disclosure pertains to conformational epitopes in TDP-43, antibodies thereto and methods of making and using immunogens and antibodies specific thereto.
Patent CA-3065494-A1 (CA)
Title: Feed thru disconnect/test terminal block
Inventor: WYDOTIS LEONARD
IPC: H01R9/28
Filed: 2017-11-06
Abstract: A disconnect/test terminal block may include a body including a front side and a back side including a protruding part. The block may include at least one circuit element disposed in the body. The block may include at least one case wire terminal disposed on the front side of the body and coupled to the at least one internal circuit. The block may include at least one field cable terminal disposed on the protruding part and coupled to the at least one internal circuit.
Patent CA-3066475-A1 (CA)
Title: An incontinence treatment system and methods of use
Inventor: JAMES NICOLE
IPC: A61F13/15
Filed: 2018-06-26
Abstract: Described herein is an incontinence treatment system and method of use. In certain embodiments the incontinence treatment system comprises a rear incontinence member capable of being releasably coupled to a front incontinence member. For example, in one certain embodiment the rear incontinence member includes a rear absorbent region, a rear outer layer coupled to the rear absorbent region, and a plurality of coupling members. The front incontinence member typically includes a front absorbent region and a front outer layer coupled to the front absorbent region, a support material being disposed around at least a portion of the front absorbent region, and one or more coupling regions being configured and arranged to engage at least a portion of the plurality of coupling members to couple the rear incontinence member to the front incontinence member.
Patent CA-3066808-A1 (CA)
Inventor: BENNETT DAVID B
IPC: G01M3/26
Filed: 2018-08-07
Abstract: Les modes de réalisation de l'invention comprennent des systèmes et des procédés permettant d'enregistrer un profil de pression à l'aide d'un capteur relié à une conduite d'écoulement, de générer une impulsion de pression dans la conduite d'écoulement par la fermeture d'une soupape reliée à la conduite d'écoulement, de calculer un premier dérivé et un second dérivé du profil de pression, et de déterminer un paramètre de l'impulsion de pression en fonction du premier dérivé et du second dérivé du profil de pression.
Patent CA-3067602-A1 (CA)
Inventor: CHADWICK ERIC MARTIN
IPC: A61K35/17
Filed: 2018-06-29
Abstract: Provided herein is a model, in particular a mouse model, for assessing or evaluating toxicity to an immunotherapy, for example a therapeutic cell therapy, such as a cell therapy containing engineered cells, such as T cells, expressing a recombinant receptor, e.g. a chimeric antigen receptor (CAR). Also provided is a method for generating the mouse model. Also provided herein are methods of use for the mouse models of toxicity, such as to evaluate modified or alternative immunotherapies, and/or to evaluate test agents, including agents to assess as potential interventions to reduce, prevent, or ameliorate toxicity to immunotherapy in human subjects and/or for use in combination with an immunotherapy, e.g. CAR-T cell therapy.
Patent CA-3068493-A1 (CA)
Inventor: GERSHON ILAN
IPC: H02J50/00
Filed: 2020-01-17
Abstract: ABSTRACT A charger device for wirelessly charging a device. The charger device includes a plug portion and a support portion. The plug portion includes an electric plug that protrudes from the plug portion. The support portion and the plug portion are rigidly connected. At least one wireless charger circuit is disposed in the support portion, and the wireless charger circuit is electrically connected to the electric plug when the plug portion and the support portion are connected. In some example embodiments, the support portion includes an inclined surface. In some example embodiments, the support portion includes a ledge. In some embodiments, the plug portion is replaceable. In some example embodiments, the charger device includes a coupler for electrical connection to the electric plug.