baber/WOPTO huggingface dataset:
Patent MA-39149-A1 (MA)
Title: Analogues de cortistatine et synthèses et utilisations associées
Inventor: SHAIR MATTHEW
IPC: C07K16/26
Filed: 2014-12-24
Abstract: L'invention concerne des composés de formule (a), (b), (c), (d) et (e), leurs sels, sels d'amines quaternaires et n-oxydes pharmaceutiquement acceptables, ainsi que des compositions pharmaceutiques les contenant. Les composés de formule (a), (b), (c), (d) et (e) devraient être utiles comme agents thérapeutiques pour le traitement d'une grande variété d'états, par ex., mais sans s'y limiter, des états associés à l'angiogenèse et et à l'activité de la kinase cdk8 et/ou cdk19. L'invention concerne en outre des procédés d'inhibition de l'activité de la kinase cdk8 et/ou cdk19, des procédés de modulation de la voie de la ß-caténine, des procédés de modulation de l'activité de stat1, des procédés de modulation de la voie de tgfß/bmp, des procédés de modulation de l'activité de hif-1-alpha dans une cellule et des procédés d'augmentation de l'expression de bim pour induire l'apoptose, à l'aide d'un composé de formule (a), (b), (c), (d) ou (e). L'invention concerne en outre des mutants ponctuels de cdk8 et de cdk19 et leur procédés d'utilisation.
Patent MA-47355-A1 (MA)
Title: Systèmes et procédés permettant de déterminer le moment de la récolte destinés à une matière végétale dans une mini serre de culture
Inventor: MILLAR GARY BRET
IPC: G05B15/02
Filed: 2018-05-30
Abstract: La présente invention concerne des systèmes et des procédés permettant de déterminer le moment de la récolte, destinés à un chariot situé dans une mini serre de culture à ligne d'assemblage, consistant à identifier un type de la matière végétale positionnée dans le chariot, à détecter un poids de matière végétale de la matière végétale à l'aide d'un capteur de poids, une hauteur de matière végétale de la matière végétale à l'aide d'un capteur de distance et/ou un niveau de chlorophylle de la matière végétale à l'aide d'une caméra, à déterminer que le poids de matière végétale détecté, la hauteur de matière végétale détectée et/ou le niveau de chlorophylle détecté satisfont des paramètres de moment de récolte, et en réponse à la détermination selon laquelle le poids de matière végétale détecté, la hauteur de matière végétale détectée et le niveau de chlorophylle détecté satisfont aux paramètres de moment de récolte, à diriger le chariot vers un système de récolte.
Patent UY-23521-A1 (UY)
Title: Una maquina y un metodo para alinear pescado
Inventor: WADELL LARS GUSTAF ALBERT
IPC: A22C25/06
Filed: 1992-12-17
Abstract: Se describe una máquina para alinear pescado, caracterizada porque comprende un aparato de alimentación desordenada para alinear y descargar pescado en una sola fila, un transportador para recibir el pescado alineado y descargado, un sensor para detectar la dirección de orientación del pescado sobre el transportador, y medios controlados por el sensor para orientar el pescado en la misma dirección. La figura 1 representa una vista en sección lateral esquemática de la máquina de conformidad con el presente invento.
Patent UY-28616-A1 (UY)
Title: Pentafluorosulfanilbenzoilguanidinas, procedimiento para su preparación, su uso como medicamento o coadyuvante de diagnostico, y medicamento que las comprende.
Inventor: KLEEMANN DR HEINZ-WERNER
IPC: C07C381/00
Filed: 2004-11-12
Abstract: Pentafluorosulfanilbenzoilguanidinas de la fórmula I en que R1 a R4 tienen los significados establecidos en las reivindicaciones, son adecuados, por ejemplo, como medicamentos antiarritmicos con un componente cardioprotector para la profilaxis del infarto y el tratamiento del infarto y para el tratamiento de la angina de pecho. También inhiben de forma preventiva los procesos patofisiológicos asociados con el desarrollo de lesiones inducidas por isquemia, especialmente en el desencadenamiento de arritmias cardíacas inducidas por isquemia.
Patent UY-28834-A1 (UY)
Title: Disposición de recipiente y cierre
Inventor: BOOTH PETER
IPC: B65D43/02
Filed: 2005-03-31
Abstract: Recipiente que comprende un recipiente con un extremo abierto y un cierre para el mismo, y por lo menos, una proyección que se extiende parcialmente, alrededor de su superficie externa. El cierre comprende una cubierta que se extiende sobre la abertura del extremo superior y un faldón; y presenta una porción superior y otra inferior, con una configuración ascendente para montar y retirar la cubierta del recipiente, y otra descendente enganchable con la saliente del recipiente, para retener la cubierta en el recipiente. La porción inferior del faldón se divide en, al menos, dos secciones periféricas pequenas de configuraciones ascendente y descendente, independientes una de la otra.
Patent UY-30508-A1 (UY)
Title: Fungicida natural a la base de eucalyptus sp
Inventor: TESSMANN WALTER SZORTIKA
IPC: A01N25/22
Filed: 2007-07-26
Abstract: A base de aceite esencial con un emulsionante natural en solucion acuosa, tratándose particularmente del aceite esencial de Eucalyptus sp emulsionado con lecitina de arroz o goma, de modo que forme una emulsion de agua en aceite destinada a la aplicacion en plantaciones por algun medio adecuado. Caracterizado por basarse en la dispersion coloidal del aceite esencial de eucalipto con emulsionante de lecitina de arroz o goma, preferentemente, en la siguiente proporcion: - Aceite esencial de Eucalyptus sp ................................10,00% en volumen; - Emulsionante natural.................................................... 10,00% en volumen; - Agua............................................................................. 80,00% en volumen.
Patent ZW-14285-A1 (ZW)
Title: Percutaneous anaesthetic composition for topical application and associated method
Inventor: DERMOT MCCAFFERTY
IPC: A61K31/245
Filed: 1985-09-04
Abstract: A composition for topical percutaneous anaesthesia comprises an anaesthetic e.g. amethocaine, dispersed in an aqueous gel e.g. methylcellulose or sodium carbopol and water. Amethocaine stability is enhanced by the gel matrix.
Patent ES-172204-A1 (ES)
Title: UN PROCEDIMIENTO PARA LA PRODUCCIoN DE ESTEROLES Y SUS PRODUCTOS DE ADICIoN, PARTIENDO DE MATERIALES QUE CONTIENEN ESTEROL
Filed: 1946-01-03
Abstract: Procedimiento para obtener esteroles o sus productos de adición partiendo de materiales que los contiene caracterizado por el hecho de que los esteroles se convierten en sus productos de adición por medio de sales satélites o de compuestos capaces de producir sales metálicas especialmente sales capaces de formar compuestos con alcoholes alifáticos bajos o con fenoles mono o polivalentes siendo los productos de adición separados del resto del material con preferencia por medio de disolventes orgánicos.
Patent ES-178439-A1 (ES)
Title: Mejoras en o relativas a sistemas de senalizacion por impulsos eléctriocs
IPC: H03K3/37
Filed: 1947-06-14
Abstract: Mejoras en sistemas de señalización proa impulsos eléctricos caracterizados por un dispositivo retardador de tiempo para un impulso eléctrico que comprende un circuito adaptado para crear un potencial de control una válvula termoiónica medios para aplicar un potencial de polarización a la válvula de modo que incialmente está en condición conductiva un dispositivo disparador conectado a dicho circuito medios para aplicar el impulso para accionar el dispositivo disparador de tal modo que inicie la formación del potencial de control y para que corte la válvula medios para comunicar el potencial de control a la válvula de tal modo que se haga conductiva después de una retardación determinada por el potencial de polarización aplicado a la misma medios para variar dicho potencial de polarización y medios para derivar un impulso de salida de dicha válvula.
Patent ES-185144-A1 (ES)
Title: UN APARATO PARA PRODUCIR UN REGISTRO DE TIRA DE UNA LiNEA DE TEXTO JUSTIFICADA, DE LONGITUD PREDETERMINADA
IPC: B41B25/00
Filed: 1948-09-07
Abstract: Aparato para producir un registro de tira de una línea de texto justificada de longitud predeterminada en la cual los caracteres y espacios de la línea de texto están representados por señales de clave; aparato que comprende un trayecto que tiene elementos colocables un mecanismo automático accionado por teclas y que incluye un circuito eléctrico para registrar sucesivamente en al tira las señales de clave que representan los caracteres y espacios de la línea y para mover sucesivamente un elemento colocable en dicho trayecto en distancia correspondiente a la anchura de cada uno de los caracteres sucesivos y una anchura de espacio normal para cada uno de los espacios de la línea de texto; dicho mecanismo automático incluye también medios para mover separadamente un segundo elemento colocable en dicho trayecto en la misma dirección que el primero para medir por separado en el una anchura normal duplicada para cada espacio de la línea un mecanismo accionado por teclas para dividir la distancia de espacio total medida por separado en el trayecto más cualquier exceso o deficiencia en la línea medida por el número de espacios de la misma determinando así la anchura exacta de los espacios en la linea del texto y un mecanismo accionado por el mecanismo divisor movido por la tecla para registrar en al tira un símbolo que representa dicha anchura de espacio en asociación con las señales de clave para la línea de texto de que se trate.
Patent ES-187732-A1 (ES)
Title: SISTEMA DE REFIRGERACIoN DE EVAPORACIoN PARA MOTORES HORIZONTALES DE PISToN
Filed: 1949-04-06
Abstract: Sistema de refrigeración de evaporación para motores horizontales de pistón caracterizado porque la cámara de agua de refrigeración se extiende por toda la longitud del cilindro y del cárter del cigüeñal y no sobrepasa en ningún sitio la dimensión de anchura del cárter del cigüeñal.
Patent ES-188373-A1 (ES)
Title: UN PROCEDIMIENTO PARA LA FABRICACIoN DE POLVO GRANULADO O SIMILAR METáLICO FáCILMENTE INFLAMABLE, DE ALEACIONES DE MAGNESIO Y ALUMINIO
Filed: 1949-05-24
Abstract: Procedimiento para la fabricación de un polvo granulado o similar metálico fácilmente inflamable de aleaciones de magnesio y aluminio caracterizado porque la porción de los diversos componentes de la aleación se escoge de modo que con una velocidad de oxidación aproximadamente la máxima se logre también al mismo tiempo que el calor libre alcance el valor más elevado posible.
Patent ES-191060-A1 (ES)
Title: MEJORAS EN LA CONSTRUCCIoN DE AMORTIGUADORES PARA BICICLETAS
Filed: 1949-12-31
Abstract: Mejoras en la construcción de amortiguadores para bicicletas caracterizadas porque cada amortiguador que se inserta en los brazos de la horquilla u horquillas del vehículo está constituido por un disco central solidario de una pieza que se acopla o inserta en el extremo superior de la parte inferior del brazo cuyo disco lleva varios alojamientos distribuidos a la misma distancia del eje en los cuales van colocados tetones de goma o material elástico apropiado.
Patent ES-255133-A1 (ES)
Title: Substituted dihydrobenzothiadiazines
IPC: C07D/
Filed: 1960-01-20
Abstract: The invention comprises compounds of the general formulae: <FORM:0863474/IV (b)/1> <FORM:0863474/IV (b)/2> (wherein R represents a hydrogen atom, a cyclohexyl, phenyl, benzoyl, furyl or pyridyl group, or a group <FORM:0863474/IV (b)/3> wherein X is a straight or branched hydrocarbon group, which may contain a carbon-to-carbon double, Y is a hydrogen atom, a phenyl group or a C2-6 carbalkoxy group, and Z is a hydrogen, fluorine, chlorine or bromine atom, a hydroxy, C1-5 alkoxy, C2-8 acyl, C2-6 carbalkoxy, nitro or benzylmercapto group, a phenyl group optionally substituted by a fluorine, chlorine or bromine atom or a C1-5 alkyl or alkoxy group, or a phenoxy group optionally substituted by one or more fluorine, chlorine or bromine atoms or a nitro or amino group R1 represents a hydrogen, fluorine, chlorine or bromine atom or a trifluoromethyl, methyl methoxy or nitro group R2 represents a methyl group, and R3 an alkyl, haloalkyl, acyl, carbalkoxy or carbalkoxymethyl group, the alkyl or alkylene radical of said groups containing not more than 2 carbon atoms, or R2 and R3 jointly form a spirocyclic polymethylene group optionally substituted by a fluorine, chlorine or bromine atom or a C1-5 alkyl group), and the production thereof by reacting, respectively, 5-trifluoromethyl 2,4-disulphamylaniline with an aldehyde RCHO or a reactive derivative thereof (followed, if desired, by reduction of any nitro group in the product to an amine group), or a compound of the general formula: <FORM:0863474/IV (b)/4> with a ketone R2-CO-R3 or a reactive functional derivative thereof. Specified reactive derivatives of aldehydes are polymers, acetals, hydrosulphites and cyanhydrins thereof, a -haloalkyl ethers and vinyl esters and ethers, and it is further stated that 1, 1-diiodoalkanes react analogously. Specified reactive functional derivatives of ketones are their ketals, enolethers, hydrosulphites and cyanhydrine. The products are useful soluratic agents. According to the second Provisional Specification, the compounds unsubstituted or monosubstituted in position 3 may also be produced by reduction of the corresponding compounds containing a double bond in the 3 : 4 position, and those unsubstituted in position 6 by hydrogenation of the corresponding 6-halo compounds, the latter reaction in some cases taking place simultaneously with the former. The third and fourth Provisional Specifications also describe the former reaction, with, in the latter, simultaneous reduction of a nitro to an amine group in some instances. Specification 826,923 is referred to in the second and fourth Provisional Specifications.
Patent ES-298633-A1 (ES)
Title: Power-assisted steering with adjustment of power participation
IPC: F16F9/22
Filed: 1964-04-13
Abstract: Power-assisted steering mechanism for a motor vehicle includes means operable whilst the vehicle is in use for adjusting the precompression of spring means which determines the degree of effort applied to the steering wheel before the power-assistance becomes operative. A series of disc springs 39 arranged to resist relative axial displacement between a nut 21 on a screwed spindle 6 connected to the steering shaft and a piston 15 linked to a shaft 10 coupled to the steerable wheels is adjustably pre-compressed by male and female nuts 42, 43 which are connected by longitudinal splines 44 so as to be conjointly rotated by a pinion 46 meshing with teeth 45 on the female nut 42 and are in respective screw-threaded engagement with a tubular body 19 attached to the piston 15 and a tubular member 23 attached to the nut 21. The pinion 46 is displaceable with the nut 21 along a splined spindle 48 rotated by driver-operated control mechanism. The disc springs 39 are graduated in size to provide a progressive spring rate as successive elements are compressed. Pressure fluid supplied through an inlet 28 to a chamber 31 on one side of the piston 15 flows when the mechanism is in the straight-ahead position through ports 36 in the piston 15, past ports 33 communicating with a chamber 30, the other side of the piston, through ports 38 in a valve core 24 carried by the tubular member 23 and to a discharge chamber 32 through the interior of the spindle 6. A distributer 25 mounted between the tubular body 19 and member 23 with provision for limited axial displacement is moved relative either to the body 19 or member 23 and against the action of springs 26, 27 upon steering in either direction to cover the ports 36 and increase pressure in the chamber 31, or to cover the ports 38 resulting in incresaed pressure on the larger piston area exposed to the chamber 30. " Feel " is provided by annular chambers 34, 37 containing pressure fluid which exerts on diametral steps in the core 24 and distributer 25 pressures equal to those exerted on the piston faces. In another embodiment (Fig. 6, not shown), a cam ring replacing the nuts 42, 43 is rotatable by the pinion 46 into three positions of adjustment in which either one, two, or three sets of coil or disc springs arranged in series in place of the springs 39 are operative.
Patent ES-322058-A1 (ES)
Title: Improvements in or relating to load transporting trucks and installations appertaining thereto
IPC: B66F9/06
Filed: 1966-01-21
Abstract: A load-handling truck in a warehouse installation with racks 7 delimiting parallel lanes 8 of width only slightly greater than that of the truck, comprises a chassis 10 supported by three axles 16, 17, 18, the last of which is a driving axle. The front axle 16 has paired wheels 19, 20 of different diameters, the first of rubber to run on the floor 22 and the second of metal to roll on guide rails 21, disposed on the floor 22 of the lanes 8. Drum type brakes are provided on the front axle 16. The central axle 17 has only metal wheels, to roll on the rails 21 while the rear axle 18 has only driven rubber floor wheels and is mounted so as to be able to move relative to the chassis 10. A vertically displaceable horizontal platform 12 is mounted within a turret 11 arranged for rotation about a vertial axis so that loads may be drawn on to or expelled from both sides of the truck by two extendible chains 34 each of which, when retracted, is wound up, and, when extended, is pushed out as a rigid member. The chains 34 are extended at high speed when a button (67), Fig. 13 (not shown), on a control panel, is pushed, until a feeler 64, Fig. 12, contacts a bar 61, Fig. 11, on the end of a receptacle 60. A micro-switch is then automatically tripped and the chains 34 continue to advance at reduced speed. When the feeler 64 is almost completely retracted a new contact trips and the chains 34 are stopped completely as pawls 56 drop into a seating 62. By pressing a button (68) the receptacle is withdrawn at reduced speed. Other buttons, (69), (70) are respectively used to push the load from the platform 12 at reduced speed and to withdraw the chains 34 at high speed. The upper part 37 of the turret 11 is guided by rollers 38 cooperating with rails 39 on the racks 7. The truck carries removable transfer shelving 13 into which a plurality of separate loads of merchandise may be placed for transportation. The turret 11 may be movable relative to the truck. A jack (not shown) or lazy-tongs (not shown) may replace the chains 34.
Patent ES-333578-A1 (ES)
Title: Vehicle transmission and controls therefor
IPC: F16D67/04
Filed: 1966-11-19
Abstract: A reversing gear comprises an output shaft 4 with integral pinions 6, 7 respectively meshing pinions 8, 34 on parallel output and reversing layshafts 9, 33 engaged by forward and reverse drive disc clutches 11, 111, the shaft 9 also carrying a brake 22 and a pinion 20 meshing a pinion 35 on shaft 33 and integral with the output member of clutch 111, the brake and clutches being under independent hydraulic control. The control arrangement includes a brake valve 39 with inlet and exhaust ports 42, 50 and outlet supply ports 41, 43 respectively connected to a clutch selector valve 54 and to the brake 22. The valve 39 is controlled by a hand lever 45 normally held disengaged by a spring 53 and carrying roller bearing members 44, 51 engageable with valve plungers 40a, 52. When handle 45 is thus held brake ports 43, 50 are vented to exhaust and ports 41, 42 are connected to admit pressure fluid to the selector valve 54 through port 41. Initial movement of lever 45 to the left engages members 40a, 44 to move a valve spool 40 to the left against a weak spring 47 to cut off the clutch supply port 41 and open the brake supply port 43, further movement of the lever compressing a second stronger spring 46 to permit engagement of members 51, 52 to operate a relief valve 49 through a spring 48 to regulate the brake supply pressure. The clutch selector valve 54 is operated by a second hand lever 63 operating a spool element 55 controlling the admission of pressure fluid to the forward or reverse drive clutch through port 56 or 57. The system is particularly applicable to the forward and reverse drive of a track of a crawler tractor, the brake being operable to brake the vehicle irrespective of the direction of travel, while the control valves permit disengagement of both the forward and reverse drive clutches when the brake is engaged. The jointly controllable clutch - brake system and the control valves form the subject matter of divisional Specifications 1,145,127 and 1,145,128 respectively.
Patent ES-334429-A1 (ES)
Title: Improvements relating to methods of strengthening glass objects
IPC: C03C17/02
Filed: 1966-12-12
Abstract: To strengthen glass objects, two layers of glaze or enamel are applied, the first having a lower co-efficient of expansion than the glass, the second having one not more than 50+10-7 higher than the first and the second layer also has a lower softening temperature than the first layer and has a thickness not more than 1À5 times that of the first layer. The glass base is preferably that disclosed in Specification 1,051,703, a particular example used having in per centages by weight SiO 2 48À6 Al 2 O 3 26À3 Na 2 O 25À1. The thickness of the first layer is preferably for 50Á to 200Á, and is of a crystalline glaze with composition ZnO 67À1 B 2 O 3 29À0 SiO 2 3À9. The top glaze is ZnO 8 PbO 56 Al 2 O 3 3 B 2 O 3 18 SiO 2 15 which may have (in gms. to 100 gms. of the glaze) Fe 3 O 4 4 MaO 2 6 to give a brown glaze.
Patent ES-339457-A1 (ES)
Title: Retrosteroid a-ring formation
IPC: C07C59/205
Filed: 1967-04-18
Abstract: A process for the preparation of 9#,10[alpha]- steroids of formula wherein R1 and R2 each represent hydrogen, C 1-6 alkyl, C 1-6 alkoxy or C 1-6 alkylthio R4 represents hydrogen or a C 1-6 hydrocarbyl group free from aliphatic unsaturation R6 and R7 each represent hydrogen, halogen, C 1-6 alkyl, C 1-6 alkylthio or C 1-6 alkanoylthio R11 represents hydrogen, hydroxy or C 1-6 alkanoyloxy R16 represents hydrogen, hydroxy, C 1-6 alkyl, C 1-6 alkoxy, or C 1-6 alkanoyloxy, or, when there is a 17#-(acetyl, haloacetyl or hydroxyacetyl) group, R16 may also be fluorine and Z represents carbonyl, a 17#-hydroxy-17[alpha]-(C 1-6 alkanoic acid) lactone group, or a group of formula CR17[alpha]R17#, wherein either R17[alpha] is hydrogen or C 1-6 aliphatic hydrocarbyl and R17# is hydroxy or C 1-6 alkanoyloxy or R17[alpha] is hydrogen, halogen, alkyl, hydroxy or C 1-6 alkanoyloxy and R17# is acetyl, haloacetyl, hydroxyacetyl, or 1,1-ethylenedioxy-ethyl, comprises reacting a 4-oxa-steroid of formula (see Specification 1,155,512) with an organometallic compound of formula R4-CH 2 -Li or R4-CH 2- Mg-halogen, and rearranging and dehydrating the resulting 4,5-seco-3,6-cyclosteroid of formula by treatment with an acid or base.
Patent ES-343823-A1 (ES)
Title: A process for melt spinning beta-lactone polyester fibres
IPC: D01D5/08
Filed: 1967-08-08
Abstract: #-Lactone polyester fibres are produced by melt spinning the molten polyester through a die plate, followed by drawing the freshly extruded and molten fibre in a heated zone to a diameter of between and 1/ 40 of the diameter at which it was extruded, the temperature within the heated zone being above the polymer recrystallization temperature, and thereafter quickly cooling the fibre to a temperature below its recrystallization temperature. #- Lactones having a mono- or di-substituted alpha-carbon atom are the preferred polymer, especially [alpha],[alpha]-dimethyl-#-propiolactone. Preferably the die plate is maintained at a temperature above the extrusion temperature of the polyester, and suitable melt spinning temperatures range between 250-333 C. The temperature of the heated zone is suitably 177-305 C., and that of the cooling zone preferably below 66 C., especially below 38 C.