baber/WOPTO huggingface dataset:
Patent CA-2835522-A1 (CA)
Title: Focused evolution of hiv-1 neutralizing antibodies revealed by crystal structures and deep sequencing
Inventor: MASCOLA JOHN R
IPC: C07K16/10
Filed: 2012-03-23
Abstract: Antibody VRC01 represents a human immunoglobulin that neutralizes -~90% of diverse HIV-1 isolates. To understand how such broadly neutralizing HIV-1 antibodies develop and recognize the viral envelope, we used X-ray crystallography and 454 pyrosequencing to characterize additional antibodies from HIV-1-infected individuals. Crystal structures revealed a convergent mode of binding of different antibodies to the same CD4-binding-site epitope. Antibody recognition was achieved through the evolution of complementary contact domains that were generated in diverse ways. Phylogenetic analysis of expressed heavy and light chains determined by deep sequencing revealed a common pathway of antibody heavy chain maturation confined to IGHV1-2*02 lineage that could pair with different light chains. The maturation pathway inferred by antibodyomics reveals that diverse antibodies evolve to a highly affinity-matured state to recognize an invariant viral structure, providing insight into the development and evolution of broadly neutralizing HIV-1 immunity.
Patent CA-2836541-A1 (CA)
Inventor: FOX MICHAEL
IPC: H04L12/28
Filed: 2012-05-09
Abstract: An intermediate device receives a content data message addressed to a receiving device for a communication session between a source device and the receiving device. The intermediate device substitutes adapted content data for content data of the content data message and then sends the adapted content data to the receiving device such that it appears to the receiving device that the adapted content data originated from the source device. The communication from the source device to the receiving device is intercepted by the intermediate device in a manner that is transparent to the source device and receiving device.
Patent CA-2836591-A1 (CA)
Inventor: GREENE RANDALL A
IPC: B64D43/00
Filed: 2013-12-13
Abstract: A system for safely landing an aircraft including a low range radio altimeter, a barometric altimeter, and an autothrottle control. The low range radio altimeter calculates a first height of the aircraft above ground-level, the barometric altimeter calculates a second height of the aircraft above ground-level, and the autothrottle control determines if the first height and the second height do not correlate. If the first and second heights are determined to lack correlation, then automatic thrust-control of the aircraft is stopped. In some embodiments, the second height is partially calculated by accessing a ground elevation database to obtain an elevation of the ground above sea level and determining a difference between the elevation of the ground above sea level and an elevation of the aircraft above sea level.
Patent CA-2842129-A1 (CA)
Inventor: SHARKH SULEIMAN MAHMOUD
IPC: H02K7/18
Filed: 2012-08-09
Abstract: The invention relates to the generation of electricity from flowing fluid and in the preferred embodiment to a horizontal axis turbine and generator assembly. The present invention is applicable to water turbines and the invention is described in relation to this application. It is however to be appreciated that it is applicable to wind turbines.The present invention provides turbine generator for generating electrical power from flowing fluid comprising a rotatable hub having an external surface and a rotational axis arranged, in use, parallel to the direction of the flow, a plurality of blades mounted on the external surface of the hub and extending radially outwards from the hub; a plurality of magnets mounted on a surface inside the rotatable hub said surface arranged to rotate with the rotatable hub thereby forming a rotor of an electrical generator, and a plurality of non-rotating coils fixed to a stationary cylindrical core within the periphery of the rotatable hub, said coils and core thereby forming a stator of the electrical generator.
Patent CA-2843709-A1 (CA)
Title: Adaptive media transmission processing
Inventor: GILSON ROSS
IPC: H04L9/00
Filed: 2014-02-21
Abstract: Provided are methods and systems for processing information. In one example method a first frame of a first group of frames of an information transmission can be processed. The first frame can be encoded without reference to other frames of the information transmission. Additionally, a second frame can be processed in the first group of frames. The second frame can be processed with reference to a frame from a second group of frames of the information transmission.
Patent CA-2844833-A1 (CA)
Inventor: RICE LAURA E
IPC: A61L2/16
Filed: 2012-10-12
Abstract: A composition and methods of its use, the composition comprising: a halogen source, urea, and an additional halogen stabilizer excluding urea, optionally an alkali in a concentration sufficient to provide said composition with a pH of greater than 10; and optionally excluding a stabilized bromine compound from said composition is disclosed. Additionally, a method for reducing biological activity in a process stream is disclosed. The method comprises: providing a composition to a process stream, wherein said composition contains: a halogen, urea, and an additional halogen stabilizer excluding urea, optionally an alkali in a concentration sufficient to provide said composition with a pH of greater than 10; and optionally excluding a stabilized bromine compound from said composition. The invention is also directed to compositions and methods of their use as effective biocidal agents for water streams. The composition comprises a halogen source, halogen stabilizers containing a sulfur bearing species and ammonium salts/urea, and an alkali. The sulfur bearing species includes sulfamic acid or its salt equivalent. The ratio between nitrogen mixture of sulfur bearing species and ammonium salts or urea can be optimized at any rate. By having optimized mixing ratio of halogen to stabilizer and that of ammonium salts to sulfamic acid or sulfamate, a synergistic effect occurs which both increases the efficacy of the composition as a biocide and it avoids adverse impacts on other chemicals that are present in the water stream (such as paper additives in pulp and papermaking water streams). Best of all the composition is easy to form and easy to introduce into a water stream of concern. Its introduction can be as simple as mixing two containers of reagent prior to introduction to the water process stream.
Patent CA-2845379-A1 (CA)
Title: Insertion mechanism for a drug delivery pump
Inventor: O'CONNOR SEAN M
IPC: A61M5/158
Filed: 2012-08-30
Abstract: An insertion mechanism (200) for a drug pump (10) includes an insertion mechanism housing (202); a manifold guide (220); an insertion biasing member (210) initially held in an energized state; a retraction biasing member (216) and a hub (212) connected to a proximal end of a needle (214), wherein the retraction biasing member (216) is held initially in an energized state between the hub (212) and the manifold guide (220); and a manifold (240) having a septum (230) and a cannula (234), wherein the annular space between the septum (230) and the cannula (234) defines a manifold header (242). The needle (214) and cannula (234) are inserted into the body of a user by the insertion biasing member(s) (210), after which only the needle (214) is retracted. Retraction of the needle (214) may open a fluid pathway from the manifold header (242) to the body through the cannula (234). A drug delivery pump (10) includes an activation mechanism (12), a drive mechanism (100), a fluid pathway connection (300), and the insertion mechanism 200. Assembly and operation methods are provided.
Patent CA-2846527-A1 (CA)
Inventor: GASS PAUL V
IPC: A01J25/12
Filed: 2014-03-14
Abstract: A method of forming cheese shreds having a wide or modified crescent shape is provided. By one approach, the method includes preparing a block of cheese by chilling the cheese to a predetermined temperature and/or reducing the size of the cheese block into cheese portions or cubes. Next, the cheese portions or cubes are fed into a shredder with shredding blades having a sinusoidal configuration. The shredder is operated to shred the cheese into modified crescent shapes with an upper and lower curved surfaces and tapered ends therebetween. Further, the modified crescent shaped cheese shreds have improved meltability such that a smaller amount of cheese can be used to achieve greater coverage, flavor, and mouth feel, as compared to previous cheese shred configurations.
Patent CA-2848234-A1 (CA)
Inventor: KURTSCHEID FRIEDHELM
IPC: E21B23/14
Filed: 2012-09-17
Abstract: A fiber-optic cable, for use in a borehole, with at least one optical waveguide (2), at least one metallic tube (1) which at least partially surrounds the at least one optical waveguide (2), and at least one additional layer, which at least partially surrounds the at least one tube (1), wherein the fiber-optic cable includes separating means which can contribute to or cause mechanical decoupling of individual components of the fiber-optic cable.
Patent CA-2849527-A1 (CA)
Inventor: SALZER RAY
IPC: B08B9/032
Filed: 2014-04-16
Abstract: The present disclosure is directed towards devices, systems, and methods for clearing drain lines. A device comprising a body with an internal cavity extending between a nozzle aperture and a coupling section, the body including a base configured to couple the body to a drain line. A nozzle body disposed within the internal cavity. A  bias spring configured to retain the nozzle body in a retracted position, the nozzle body configured to extend into the drain line when the nozzle body is pressurized and the nozzle body including a nozzle configured to expel fluid in a direction of flow of the drain line.
Patent CA-2851945-A1 (CA)
Title: Window covering
Inventor: CHANG CHIH-YAO
IPC: A47H3/02
Filed: 2014-05-06
Abstract: A window covering includes a headrail, a bottom rail, a shading member, two pulley assemblies, a car, a control cord, and a transmission cord. The shading member is between the headrail and the bottom rail. The pulley assemblies and the car are received in the headrail, and the car is free for reciprocation. The control cord runs around one of the pulley assemblies and the car, and then going out of the headrail to be pulled or released by a user. The transmission cord has a main section and two branch sections, wherein the main section runs around the other one of the pulley assemblies and the car, and the branch sections go out of the headrail to be connected to the bottom rail.
Patent CA-2852928-A1 (CA)
Inventor: BOUVERIE WILLIAM M
IPC: B41J2/315
Filed: 2012-10-19
Abstract: A sensing apparatus operable for sensing top of form indicators on media within a print station is provided. The sensing apparatus generally including a base and a cover hingedly attached to each other and being operable for manipulation between an open and closed position, a flexible circuit affixed to the interior surfaces of the base and cover, the flexible circuit comprising an array of optical sensing devices, and an interface connector integral the base for connection to a control unit of a print station. The optical sensing devices generally include any one of light emitting diodes and photo sensors and are operable for the detection of holes, notches, black marks and gaps located on a media passing through the sensing apparatus.
Patent CA-2854282-A1 (CA)
Inventor: SILVA MANUEL ANTONIO COIMBRA RODRIGUES DA
IPC: C08B37/00
Filed: 2012-11-02
Abstract: The present invention relates to a winemaking method that uses the traditional vinification process, except that, after fermentation, the wine is put into contact with a chitosan-based film and no sulphur dioxide is added to the wine. The present invention also relates to a method for producing the chitosan-based film by modifying chitosan with natural compounds that make it possible to produce chitosan films that are stable in an acid environment, have high antioxidant activity and retain antimicrobial activity. In one embodiment, the films are produced by covalently bonding to chitosan molecules that increase the insolubility of chitosan in an acid environment, such as genipin, and molecules with high antioxidant activity, such as caffeic acid or grape or wine extracts that are rich in compounds with antioxidant activity.
Patent CA-2855912-A1 (CA)
Title: Call recording in a telecommunications network
Inventor: TAGG JAMES
IPC: H04W4/00
Filed: 2012-11-14
Abstract: A method of recording media transmitted to or from a first party communicating through one of a plurality of mobile telecommunications networks with a second party is described. Either the first party or the second party initiates a call with the other party. One of a set of call splitters distributed through the plurality of telecommunications networks is then determined to be a local call splitter to one of the parties. A connection is then established between the first party and the local call splitter to split the call into a recording part and a call part. The call part is routed between the first party and the second party via the call splitter to provide transmission of media between the first party and the second party, and the recording part is provided by the local call splitter to a recording service associated with the first party. Suitable apparatus is also described, as are methods for recording the calls of a subscriber to a central recording station using a network trigger set or a SIM application set to divert the call to a recording node.
Patent CA-2856427-A1 (CA)
Inventor: WEN CATHY
IPC: A46D3/04
Filed: 2012-11-21
Abstract: Methods of producing a unitary personal care article such as a toothbrush having an inner cavity.
Patent CA-2856671-A1 (CA)
Inventor: BURNS DUNCAN
IPC: B62D7/00
Filed: 2011-11-22
Abstract: A riding yard maintenance vehicle includes a frame, a steering assembly, a cable and at least one set of guide pulleys. Wheels of the riding yard maintenance vehicle are attachable to the frame. The steering assembly includes a steering apparatus operably coupled to front wheels of the riding yard maintenance vehicle via a cable system. The cable system includes the cable, which is wrapped around at least a portion of the steering shaft. The cable terminates at respective ends thereof at corresponding ones of a first shaped cam and a second shaped cam each of which is operably coupled to respective ones of a first axle rod and a second axle rod.  The first and second axle rods are rotatably connected to respective front wheels. The first and second shaped cams cause movement of the front wheels based on movement of the cable responsive to rotation of the steering shaft.
Patent CA-2858461-A1 (CA)
Title: Systems and methods for use in covering a portion of a fastener protruding from a surface
Inventor: CAMERON MICHAEL SCOTT
IPC: F16B43/00
Filed: 2014-08-06
Abstract: A cap (250) for use in covering a portion (212) of a fastener (210) protruding from a surface (206) is provided. The portion (212) includes threads. The cap (250) includes an interior (252), a base (258) that at least partially delimits the interior (252), a threaded receptacle (292) on the interior (252) configured to threadably engage the portion (212) of the fastener (210), and a seal (260) coupled to the base (258) to engage the surface (206).
Patent CA-2859408-A1 (CA)
Title: Humanized light chain mice
Inventor: MACDONALD LYNN
IPC: C07K16/46
Filed: 2012-12-17
Abstract: Non-human animals, tissues, cells, and genetic material are provided that comprise a modification of an endogenous non-human heavy chain immunoglobulin sequence and that comprise an ADAM6 activity functional in a mouse, wherein the non-human animals express a human immunoglobulin heavy chain variable domain and a cognate human immunoglobulin ? light chain variable domain.
Patent CA-2860783-A1 (CA)
Title: Ovule specific promoter and methods of use
Inventor: CHAMBERLIN MARK A
IPC: C12N15/82
Filed: 2012-04-12
Abstract: Compositions and methods for regulating expression of heterologous nucleotide sequences in a plant are provided. Compositions include nucleotide sequences for an Arabidopsis thaliana (AT SVL3) promoter. Also provided is a method for expressing a heterologous nucleotide sequence in a plant using a promoter sequence disclosed herein.
Patent CA-2861265-A1 (CA)
Title: Illuminating/sounding device activated by inflation for balloon
Inventor: HENRIK BO STIELER
IPC: F21V33/00
Filed: 2012-02-29
Abstract: An illuminating/sounding device used for balloon inflation startup comprises an illuminating lamp/sounder, a battery (4) and a casing (5). The casing (5) at least covers the illuminating lamp/sounder. The casing (5) has an air inlet (51), an air outlet (52) and an air channel (6). The air channel (6) connects the air inlet (51) and the air outlet (52) to form a penetrating airflow channel in the casing (5). The illuminating lamp/sounder is provided in the air channel (6). The illuminating lamp/sounder has a sealing device, through which the illuminating lamp/sounder seals the air channel (6). Before a balloon is inflated, the illuminating lamp/sounder cannot be started. After the balloon is inflated, a pressure difference formed between the inner side and the outer side of the balloon enables the illuminating lamp/sounder to move toward an external end of the air channel (6) and seal the air channel (6), and a circuit of the illuminating lamp/sounder is switched on when the air channel (6) is sealed, so that the illuminating lamp/sounder is started to work.
Patent CA-2861889-A1 (CA)
Inventor: JACKSON DAVID BRIAN
IPC: F16H15/52
Filed: 2013-01-21
Abstract: Des modes de réalisation relatifs à des composants, sous-ensembles, systèmes et/ou procédés de transmissions infiniment variables (IVT) sont fournis. Dans un mode de réalisation, un système de commande est adapté pour faciliter un changement de mode de fonctionnement d'une IVT. Dans un autre mode de réalisation, un système de commande comprend un embrayage d'entraînement couplé à une source de puissance de rotation ; l'embrayage d'entraînement est configuré de façon à engager de manière sélective une bague de traction et un support de la transmission à variation infinie. Le système de commande comprend un ensemble d'embrayage unidirectionnel configuré pour venir en prise de manière sélective avec la bague de traction et le support. Dans certains modes de réalisation, le système de commande régit l'actionnement de l'embrayage unidirectionnel pour verrouiller et déverrouiller sélectivement les composants de l'IVT. Dans certains modes de réalisation, le système de commande met en uvre un mode IVT dans lequel le support se couple de manière sélective à une source de puissance de rotation.
Patent CA-2862000-A1 (CA)
Title: Cable with non-flammable barrier layer
Inventor: CAMP II DAVID P
IPC: H01B11/06
Filed: 2012-12-17
Abstract: A cable that comprises a core that has at least one conductor, a dielectric barrier layer that surrounds the core, and a conductive shield that surrounds the core. The dielectric barrier layer is formed of a substantially non-flammable material and is devoid of fluoropolymers.
Patent CA-2863597-A1 (CA)
Title: Bone plate for elastic osteosynthesis
Inventor: BOTTLANG MICHAEL
IPC: A61F2/28
Filed: 2013-02-01
Abstract: Embodiments provide a method and device for plate osteosynthesis of a bone fracture that allows angle-stable fixation of the bone fracture, while permitting elastic axial motion at the fracture site in a controlled, symmetric manner to stimulate fracture healing. Embodiments pertain to a bone plate having an outer surface and a bone-facing surface. The bone plate incorporating internal sliding elements containing a threaded receiving hole for bone screws that have a correspondingly threaded screw head. The sliding elements undergo controlled displacement parallel to the longitudinal axis of the plate but are substantially constrained against displacement perpendicular to the longitudinal axis of the plate. The bone screws with threaded heads may be rigidly fixed to the threaded receiving holes in the sliding elements without compressing the bone plate onto the bone surface. Sliding elements are elastically suspended inside the bone plate and undergo dynamic motion.
Patent CA-2864276-A1 (CA)
Title: Improved methods of nucleic acid sequencing
Inventor: GORMLEY NIALL ANTHONY
IPC: C12Q1/68
Filed: 2013-03-06
Abstract: Provided herein is a method of using transposition to improve methods of sequencing RNA molecules. Provided herein is a method of tagging nucleic acid duplexes, such as DNA:RNA duplexes or DNA:DNA duplexes. The method includes the steps of providing a transposase and a transposon composition, providing one or more nucleic acid duplexes immobilized on a support, and contacting the transposase and transposon composition with the one or more nucleic acid duplexes under conditions wherein the one or more nucleic acid duplexes and transposon composition undergo a transposition reaction to produce one or more tagged nucleic acid duplexes, wherein the transposon composition comprises a double stranded nucleic acid molecule comprising a transferred strand and a non-transferred strand.
Patent CA-2865180-A1 (CA)
Title: Novel variant hyprocrea jecorina cbh1 cellulases
Inventor: DAY ANTHONY
IPC: C12N15/74
Filed: 2003-08-15
Abstract: Described herein are variants of H. jecorina CBH I, a CeI7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
Patent CA-2867371-A1 (CA)
Title: Light weight articles, composite compositions, and processes for making the same
Inventor: GUNES IBRAHIM SEDAT
IPC: C08K7/28
Filed: 2013-03-07
Abstract: Provided are composite material comprising hollow glass microspheres and a microcellular thermoplastic resin, articles molded from such materials, and methods of making such materials.
Patent CA-2867749-A1 (CA)
Title: Vesicular formulations
Inventor: MAYO JOHN
IPC: A61K31/7032
Filed: 2013-03-28
Abstract: The present invention relates to vesicular formulations for the treatment of rosacea. It also relates to a method of treating rosacea comprising administering a vesicular formulation according to the invention.
Patent CA-2868771-A1 (CA)
Inventor: SOON-SHIONG PATRICK
IPC: G06Q30/02
Filed: 2013-02-08
Abstract: Systems, methods, and use-cases of multi-modal authentications and content distribution are presented. A content consumer can capture a multi-modal digital representation of multiple objects where a juxtaposition of features derived from the digital representation can be used to recognize that at least some of the objects are a valid authentication object. Upon authentication, an authentication agent determines a content access level for content associated with the corresponding to the juxtaposition. The content can then be presented on an electronic device, possibly within a secure virtual machine, according to the content access level.
Patent CA-2868981-A1 (CA)
Inventor: HATHAWAY DAVID
IPC: H04W4/00
Filed: 2013-10-30
Abstract: A computer-readable medium comprising instructions in code which when stored in a memory of a portable electronic device and executed by a processor of the portable electronic device causes the device to execute a passenger distribution and cargo application, receive user input via a user interface of the portable electronic device indicating a passenger distribution in the aircraft, and cause the portable electronic device to transmit passenger distribution data to a remote server.
Patent CA-2871322-A1 (CA)
Inventor: KATSUYAMA BRADLEY
IPC: G06Q30/08
Filed: 2013-09-12
Abstract: The TRANSMISSION LATENCY LEVELING APPARATUSES, METHODS AND SYSTEMS ("TLL") provides an electronic bidding order management infrastructure, such as a "point-of-presence," which receives and route electronic trading orders from different trading entities at a server via a transmission medium to create a certain amount of transmission latency before the trading orders could arrive at and be executed at electronic exchanges to reduce latency arbitrage and/or order book arbitrage that may be experienced by high frequency trading participants.