baber/WOPTO huggingface dataset:
Patent JP-2006172541-A (JP)
Title: Semiconductor storage device
Inventor: AKIYOSHI HIDEO
IPC: G11C11/41
Filed: 2004-12-13
Abstract: <P>PROBLEM TO BE SOLVED: To provide a semiconductor storage device having a repeater circuit, wherein a reduction of power consumption is attained by the simple circuit constitution.  <P>SOLUTION: A cell array is divided into a plurality of blocks 11, 12. Control signal lines 71a, 71b, 72a, 72b served for a propagation of the control signal are corresponded to blocks 11, 12 and divided into 1st wiring sections 71a, 72a, and 2nd wiring sections 71b, 72b, and the repeater circuit 21 for relaying the control signal is inserted between the wiring sections. While the block 11 is selected, which receives the control signal through the 1st wiring sections 71a, 72a located closer to an output source of the control signal than the repeater circuit 21, the repeater circuit 21 does not output the control signal to the 2nd wiring sections 71b, 72b far from the output source of the control signal.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006167060-A (JP)
Title: Footwear and back band rotation restriction implement
Inventor: KAZUTAMA MASAO
IPC: A43B3/12
Filed: 2004-12-14
Abstract: <P>PROBLEM TO BE SOLVED: To provide a footwear in which an inclined angle of a backband relative to the heel portion upper surface of the footwear itself does not become smaller than a predetermined angle in the footwear having a backband whose both end portions are turnably secured.  <P>SOLUTION: In the footwear (a sandal) in which female hooks 16 secured to both the end portions of the backband 14 are turnably fitted to male hooks 18 secured to a foot dorsum skin portion 12 of the footwear, turning regulating bosses 56 are formed in the members of the female hooks 16, engaging bosses 32 are formed in the members of the male hooks 18, the turning regulating bosses 56 and engaging bosses 32 contact each other, thereby the turning angle position of the female hooks 16 relative to the male hooks 18 regulated, the inclined angle of the backband does not become smaller than the predetermined angle A.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2005178752-A (JP)
Title: Method and device for damping wheel vibration of vehicular wheel
Inventor: BARTH GUNTER
IPC: B60T8/00
Filed: 2004-12-15
Abstract: <P>PROBLEM TO BE SOLVED: To damp or eliminate wheel vibration.  <P>SOLUTION: In the method and the device for damping the vibration of the wheel (2) of the vehicle (1) generated by the drive system (4, 5, 7) of the vehicle (1), variables (ϕ, A, T) representing the vibration (S) relative to at least one wheel (2) are determined in order to damp the vibration (S). When the wheel brake (3) of the wheel (2) is operated as the function of the determined variables (ϕ, A, T), the wheel vibration (S) can be simply and effectively damped.  <P>COPYRIGHT: (C)2005,JPO&NCIPI
Patent JP-2005202384-A (JP)
Title: System and method for restoring and setting charge voltage in dual recharge system
Inventor: SHI FAN
IPC: G03G15/02
Filed: 2004-12-16
Abstract: <P>PROBLEM TO BE SOLVED: To improve color transfer in a color image forming device.  <P>SOLUTION: An operating voltage, for a split recharge image forming system having a plurality of image forming stations 130, 140, 150 and 160 separately equipped with a DC charge device (for example, 131) and an AC charge device (for example, 132), is determined. A combined target voltage level to be applied on a charge holding surface 105 in the midst of an image forming operation with the combination of the DC charge device and the AC charge device, etc., is determined on the basis of at least a determined DC grid operation voltage and at least one determined DC parameter. Further, the charging state, on the charge holding surface 105 in the midst of the image forming operation by the DC charge device and the AC charge device in the station, is measured for every image forming station. Whether or not the measured charging state is different from the target voltage level by exceeding the prescribed amount is discriminated for every station. Regarding the station discriminated as the one whose charging state exceeds the prescribed amount, the charging level for the AC charge device is adjusted in the station.  <P>COPYRIGHT: (C)2005,JPO&NCIPI
Patent JP-2005199269-A (JP)
Title: Device for discharging liquid drops, pattern forming method and method for manufacturing display device
Inventor: YAMAZAKI SHUNPEI
IPC: H01L51/50
Filed: 2004-12-16
Abstract: <P>PROBLEM TO BE SOLVED: To provide a display device capable of increasing using efficiency of materials and manufacturing with simplified manufacturing processes, and a technique for manufacturing thereof, and provide a technique capable of forming patterns such as wiring which constitutes the display device in a desired shape with excellent controllability.  <P>SOLUTION: A device for discharging liquid drops is comprised of a discharging means discharging a composition which includes pattern forming materials and a shaping means shaping the composition profile before the composition is deposited to the area to be formed, and the shaping means is arranged between the discharging means and the area to be formed.  <P>COPYRIGHT: (C)2005,JPO&NCIPI
Patent JP-2006166823-A (JP)
Title: Method for screening therapeutic medicine for sex hormone disorder
Inventor: MATSUMOTO SHUNICHIRO
IPC: G01N33/50
Filed: 2004-12-17
Abstract: <P>PROBLEM TO BE SOLVED: To provide a new and simple method for screening therapeutic medicines for sex hormone disorders.  <P>SOLUTION: The present inventors prepared a knockout mouse of GPRg2 gene and analyzed a phenotype and found that testis which is a tissue for secreting testosterone which is an exacerbation factor for androgenic disorders notably shrinks in the knockout mouse, compared with that of a wild type mouse. These inventors further found that ovary which is a tissue for secreting estrogen causing female hormone disorder remarkably shrinks in the knockout mouse, compared with that of a wild type mouse. These inventors provided GPRg2 polypeptide and a cell expressing the polypeptide as a screening tool for therapeutic medicines for sex hormone disorder by these knowledge. These inventors, further, built a system for screening therapeutic medicines for sex hormone disorders using the GPRg2 polypeptide to complete the present invention.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006173447-A (JP)
Title: Magnetizer
Inventor: HORI MITSUTAKA
IPC: H01F13/00
Filed: 2004-12-17
Abstract: <P>PROBLEM TO BE SOLVED: To provide a magnetizer that does not cut off the magnetize current at peak and uses the first half wave of the resonance current to regenerate the residual energy in L1 and C1 when the magnetize current is supplied to the magnetizer coil L1 though ON control over the magnetizer switching element by means of the charging voltage of the charging capacitor C1.  <P>SOLUTION: A magnetizer switching element is SCR, etc. that becomes conductive through ON control but becomes non-conductive when the conductive current lowers below a predetermined level. A charging SCR3 is placed between a rectification circuit 2 and C1 and a regeneration series circuit made of a regeneration coil L2 and a regeneration SCR2 is connected to C1 in parallel. C1 is charged through ON control over SCR3, the magnetizing SCR1 is subject to ON control at the end of charging, the regeneration SCR2 is subject to ON control at the half cycle of the resonance current by means of L1 and C2 from that timing, and then the reverse voltage being charged into C1 by L1 is regenerated in C1 as positive voltage by means of the resonance current of L2 and C1.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006190702-A (JP)
Title: Apparatus and method of manufacturing flexible printed substrate
Inventor: KAWAMURA HIROAKI
IPC: H05K3/00
Filed: 2004-12-17
Abstract: <P>PROBLEM TO BE SOLVED: To provide an apparatus and a method of manufacturing in which a thin film is formed in a flexible substrate with high adhesiveness without raising a manufacturing cost without the necessity for using an adhesive being a trouble for the microfabrication of wiring in order to form the thin film in the flexible substrate and to make as the flexible printed substrate and further in which neither wrinkle nor curling, etc. is generated in the obtained flexible printed substrate.  <P>SOLUTION: In the apparatus of manufacturing the flexible printed substrate to form a metal thin film layer in a vacuum tub at the flexible substrate top, the vacuum tub has a plasma treatment means, a sheet layer forming means, a metal thin film layer forming means, and a heating rolling means sequentially in order in the conveyance direction of the above flexible substrate. The sheet layer forming means and the thin film layer forming means are provided along the circumferential direction of a main roller for winding the flexible substrate and conveying it and heating the flexible substrate.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2005109521-A (JP)
Title: Surface treatment method and silicon wafer
Inventor: NOGAMI SHOJI
IPC: H01L21/205
Filed: 2004-12-20
Abstract: <P>PROBLEM TO BE SOLVED: To fully remove a natural oxidation film and organic matters, even if hydrogen-baking temperature is decreased, in a surface treatment method of silicon wafer and a semiconductor wafer.  <P>SOLUTION: The surface treatment method of the silicon wafer is performed, before a semiconductor thin-film is epitaxially grown on an silicon wafer surface. This method has a hydrogen-baking step for heat-treating the silicon wafer surface by using hydrogen as an atmospheric gas, and the hydrogen-baking step is performed on the conditions that the relational expression P<3×10<SP>17</SP>t<SP>0.5943</SP>e<SP>-36.549 (1000/T)</SP>be satisfied, where P is the pressure (Pa), t is the heat-treating time (min) and T is the heat treatment temperature (K).  <P>COPYRIGHT: (C)2005,JPO&NCIPI
Patent JP-2006149342-A (JP)
Title: Food and nutritive adjuvant comprising eel roe and sperm themselves or their extracts as main materials or auxiliary materials and method for producing the same
Inventor: ITO SHUJI
IPC: A23L17/30
Filed: 2004-11-25
Abstract: <P>PROBLEM TO BE SOLVED: To provide a nutritive adjuvant which makes possible to efficiently and continuously take eel roes and sperms themselves or their extracts and further surely grasp the intakes of nutritive ingredients, and to provide a method for producing the same.  <P>SOLUTION: This method for producing the nutritive adjuvant comprises a pretreatment process for preliminarily washing eel roes and sperms themselves or their extracts, a thermal treatment process for sterilizing and parasite-removing the pretreatment product, a finely grinding treatment process for finely grinding the thermal treatment product, a drying process for drying the finely ground product, and a pulverization treatment process for pulverizing the dried product. The powder obtained by the production method can be used as a nutritive adjuvant in the powder state as such, added to other foods, or extracted into liquids or pastes.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006174794-A (JP)
Title: Traveling vehicle body
Inventor: SAEKI MASABUMI
IPC: A01B63/10
Filed: 2004-12-24
Abstract: <P>PROBLEM TO BE SOLVED: To facilitate an easy and safe attaching/detaching operation of a work machine on a traveling vehicle body provided with a hitch which attaches and detaches the work machine, installed on the top end of an up/down turnable link which turns by an up/down actuator installed on the end of the vehicle body.  <P>SOLUTION: The traveling vehicle body is provided with a controlling device and the up/down link 14 installed on the vicinity of the end part of the body. A lift up switch 90 and a lift down switch 91 are installed on the vicinity of the up/down link 14 each respectively lifts up or lifts down the up/down link 14. The controlling device turns the up/down link 14 at a constant amount by every operation of the lift up switch 90 and the lift down switch 91 and continuously turns the up/down link 14 only during the operation of the lift up switch 90 and the lift down switch 91.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006183459-A (JP)
Title: Brayton cycle engine
Inventor: AOYAMA SHUNICHI
IPC: F01L13/00
Filed: 2004-12-24
Abstract: <P>PROBLEM TO BE SOLVED: To solve the problem of basic load control of a Brayton cycle engine, by supplying proper compressed air or an air-fuel mixture without a loss, without squeezing fresh air of high pressure, by controlling the combustion chamber volume in the piston top dead center in response to a load.  <P>SOLUTION: This Brayton cycle engine has a piston 322 reciprocating in a cylinder 323, a supercharging means 2 arranged in an intake system and supplying air of higher pressure than atmospheric pressure, an intake valve 212 arranged in the cylinder 323, opening and closing when the piston 322 exists in the vicinity of the top dead center and adjusting a supply quantity of the air supplied from the supercharging means 2 to the cylinder 323, an operation state detecting means 50 for detecting an engine operation state, and a top dead center position changing means 30 for changing a top dead center position of the piston 322 on the basis of the detected engine operation state.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006184110-A (JP)
Title: Navigation apparatus
Inventor: TOMINAGA HIROYUKI
IPC: G09B29/00
Filed: 2004-12-27
Abstract: <P>PROBLEM TO BE SOLVED: To provide a navigation apparatus for eliminating the sense of incongruity and uneasy feeling of a user who is guided in the direction opposite to the destination place.  <P>SOLUTION: The navigation apparatus 100 searches a guide route from information on a map, a current location and the destination place, and is provided with an intersection arriving/leaving route determining means 6 for determining whether an intersection located on the searched guide route and guiding a turn is included in a special turn route for turning a direction by a plurality of the turns; and a guide content determining means 7 and a sound generating means 8 for implementing the sound announcement for indicating that the intersection is included in the special turn route, when the intersection is attained within a predetermined distance.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006186713-A (JP)
Title: Mobile telephone terminal
Inventor: KUSANO EIICHIRO
IPC: H04M1/247
Filed: 2004-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To easily start another function during the operation of one function.  <P>SOLUTION: When the functions are allocated to the prescribed numeric keys and the functions are operated, a function start part 15 allows a CPU 2 to start another function concerning the prescribed keys under the condition that the depression of a specified key (special start key) different from any other prescribed keys and the continuous depression of the same prescribed keys (one or more prescribed keys can be set) by not less than prescribed depressing times. The function is instantaneously changed over into another function by one-time key depression when a mobile telephone terminal is in a stand-by state, or when changeover can be performed without requiring the continuous depression of the prescribed keys and also the function is being operated. The depression of the special start key is required. Thereby, one function such as a mail function is previously started and being operated by the continuous depression of the keys, so that user is reminded not to unexpectedly terminate the function during an input operation.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006185269-A (JP)
Title: Facility reservation system, facility reservation method, and recording medium
Inventor: MORI RYOKO
IPC: G06Q50/00
Filed: 2004-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a facility reservation system capable of introducing a service organization such as the store of a surrounding area providing information on a service content, and taking over a reservation processing with the service organization in order to effectively use a reservation time zone through the use of information on the reservation time zone in using facilities by allowing a user to retrieve and reserve the facility suitable for the desired time zone and place about the facility such as a locker or a parking lot, and to reserve the rental facility.  <P>SOLUTION: The facility reservation system is connected to a terminal to be operated by the user who desires the usage of the facility via a network, so as to reserve the usage of the facility having a remotelly controllable electronic lock. The device receives a reservation request for usage from the user, retrieves the facility to be used in the place and usage time zone which the user desires, presents a facility usage condition and a discount condition for optimal selection when the user selects the facility, and reserves the facility selected by the user.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006182735-A (JP)
Title: Solid cosmetic
Inventor: KAGAMI KO
IPC: A61Q1/10
Filed: 2004-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a solid cosmetic which gives an excellent sense of use, has excellent productivity, and is sufficiently low in water separation, when stored.  <P>SOLUTION: The solid cosmetic containing water and a water-soluble gelling agent is characterized by combining agar with carrageenan as the water-soluble gelling agent.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006181621-A (JP)
Title: Spot resistance welding equipment
Inventor: KIKUCHI RYO
IPC: B23K103/04
Filed: 2004-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a conduction control method of the spot resistance welding capable of suppressing generation of spatter in the spot resistance welding and obtaining a weld part of consistent quality.  <P>SOLUTION: In the conduction control method of the spot resistance welding, electrodes are conducted so as to alternately repeating time zones 31a-31d for maintaining the current as high as to grow nugget to a steel plate to be welded, and time zones 32a-32c for maintaining the current as low as to soften the steel plate without generating spatter, during the current-carrying time of the resistance welding.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006185385-A (JP)
Title: Work schedule management method and management device therefor
Inventor: SHIKAME HIROYUKI
IPC: G06Q50/00
Filed: 2004-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To certainly manage a work schedule, and to more minutely manage it.  <P>SOLUTION: The work schedule of that day prepared from contract information and work schedule information of an employee is managed. An on duty schedule is prepared from the contract information and the work schedule information of the employee, and the work schedule information assigned in each time is prepared as roll call information of that day on the basis of designation time information of the contract information and on duty schedule information thereof. Advance notice time to work time included in the work schedule information is managed, and a display color of a corresponding display area is changed over when the advance notice time arrives. The display color is changed into yellow 10 minutes before departure scheduled time, and is further changed into red 5 minutes before. Simultaneously, an alarm also sounds. By such the display color change or the like, the advance notice is performed.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2005526292-A (JP)
Title: プロジェクションシステム
IPC: G03B21/14
Filed: 2003-05-16
Abstract: 【課題】フラッタを抑制しつつ安定器回路を簡単にしたプロジェクションシステムを提供する。 【解決手段】本発明は、プロジェクションシステム、及びこうしたシステムに用いるドライバに関するものである。本発明によれば、このプロジェクションシステムは、放電空間を密閉する放電管と第１及び第２主電極とを有する高圧放電プロジェクションランプを具えている。このシステムは、前記プロジェクションランプを、少なくとも3MHzの周波数を有するＡＣランプ電流で動作させる手段も具えている
Patent JP-2005526941-A (JP)
Title: 熱及び圧力両用のリリーフ弁
IPC: F16K17/38
Filed: 2003-05-19
Abstract: 【課題】  圧力と熱との両方に対応できる安全装置を提供する。 【解決手段】  開示される熱及び圧力両用のリリーフ弁は、第１の端部に設けられた開口と、開口へ向けて第１のハウジングにおける第２の端部から延在してなる通路と、を有してなる第１のハウジングを含んでいる。第２のハウジングは、その一部分が第１のハウジングの開口に受け入れられて、第１及び第２のハウジングは、通路に隣接したチャンバを形成する。出口通路はチャンバから弁の外部へ延在している。ベアリング要素は、チャンバ内に配置されて通路に隣接していて、通路の広さよりも大きくなっている。バネは、チャンバ内に配置されて、圧縮状態になっていて、ベアリング要素に対して一列になっている。チャンバ内には、熱要素も配置されていて、バネに対して一列になっている。熱要素は所定の温度にて溶融する。バネがベアリング要素に対して力を加えることで、ベアリング要素は通路へ向けて付勢されて、チャンバと通路との間にシールが形成される。
Patent JP-2005530890-A (JP)
Title: 水分バリア樹脂
IPC: B32B5/16
Filed: 2003-06-19
Abstract: フィルム形成性で架橋可能な部分的に加水分解された重合体と架橋剤とを含む水分バリア樹脂は、これらの樹脂を含む組成物でカプセル化された種々の粒子、物質、およびその他のコア材料に対して、水分に対して改善された不透過性および延長された放出能力を提供する。
Patent JP-2005535627-A (JP)
Title: アジュバント不含ペプチド・ワクチン
IPC: A61K39/245
Filed: 2003-06-25
Abstract: 融合ペプチドにおいて、合成由来Ｔヘルパー・エピトープであるＰＡＤＲＥ、またはいくつかの破傷風Ｔ Ｈ エピトープの１つを、ＣＭＶ−ｐｐ６５由来の免疫優性ＨＬＡ  Ａ ＊ ０２０１拘束ＣＴＬエピトープに連結すると、ＨＬＡ  Ａ ＊ ０２０１／Ｋ ｂ トランスジェニックマウスにおいて、頑強な細胞傷害性細胞性免疫応答が引き起こされた。該融合ペプチドは、皮下経路または鼻内経路いずれかによって、生理食塩水溶液中で投与された際、免疫原性である。ＣｐＧ含有一本鎖ＤＮＡ（ｓｓ−ＯＤＮ）は、アジュバントとして融合ペプチドに添加された際、どちらの経路でも、免疫認識を劇的に上方制御した。ワクシニアウイルス由来の全長ｐｐ６５タンパク質を発現するか、またはワクチンにコードされるＣＴＬエピトープで感作された標的細胞は、免疫動物由来の脾臓エフェクターに認識された。ＣｐＧ  ｓｓ−ＯＤＮ（ＤＮＡアジュバント）と組み合わせたＴ Ｈ −ＣＴＬエピトープ融合ペプチドは、安全でそして有効な方式の、非経口搬送または粘膜搬送のための有用な戦略に相当し、これは、特に非常に炎症性であるアジュバントが望ましくない、ＨＣＴのドナーまたはレシピエントのワクチン接種などの状況において、感染性疾患の管理または予防に適用可能性を有する。
Patent JP-2006507438-A (JP)
Title: 金属製の多層シリンダヘッドガスケット内のセンサ及びその結線用の装置
IPC: F16J15/06
Filed: 2003-06-30
Abstract: 本発明は、リブ（16、18）を有する下層プレート及び上層プレートの少なくとも２つのプレート（12、14）と、ベースプレート（44）と、中間プレート（48）とを含む多層シリンダガスケット装置（10）に関し、ベースプレート及び中間プレートには、円筒形状の穴（20）の縁部のすぐ近くに配置されているセンサ（30）と、このセンサから送られる情報を伝達するケーブル（36）とが含まれている。本発明は、ベースプレートと中間プレートとの間に迂回部が設けられ、この迂回部に沿って伝達ケーブル（36）が通過していることを特徴とする。
Patent JP-2005532380-A (JP)
Title: アラニルアミノペプチダーゼの阻害剤の使用および該阻害剤を含む薬学的配合物
IPC: A61K31/4164
Filed: 2003-07-04
Abstract: 【課題】  Ｔｒｅｇ細胞中／上においてＴＧＦ−β１の産生および発現を誘導するための効果的な方法を提供することを目的とし、さらにこの方法は、自己免疫疾患、アレルギー、動脈硬化症の予防および／または治療、ならびにヒトまたは動物における移植片拒絶の抑制に好適である。さらなる目的は、上記目的を達成することができる手段で相当する薬学的配合物を提供することである。 【解決手段】  本発明は、Ｔｒｅｇ細胞中および／またはＴｒｅｇ細胞上におけるＴＧＦ−β１の産生およびＴＧＦ−β１の発現の誘導のための、アラニルアミノペプチダーゼおよび／または類似の基質特異性を有する酵素の１つの阻害剤または数個の阻害剤の使用に関し、自己免疫疾患、アレルギー、動脈硬化症を予防および／または治療するための、ならびに移植片拒絶反応を抑制するための使用に関する。さらに、本発明は、病原性自己抗原のペプチド断片または合成類似体および／または病原性微生物の特異的抗原成分がさらに用いられる使用に関する。
Patent JP-2005534557-A (JP)
Title: 車両用安全装置
IPC: B60R22/26
Filed: 2003-07-09
Abstract: 本発明は、側方ガイドによって車両内部に固定される車両シートの安全装置（１）に関する。この安全装置は、ガイド間の領域に位置固定の方式によって車両内に配置される、少なくとも１つの安全レール（８）からなり、該安全レール（８）は、車両シートに接続され、又は接続されるべき、関連する安全手段（１０）を具備し、安全レールは、安全手段（１０）と、通常の乗車負荷の場合には、安全手段（１０）が、安全レール（８）に対して非接触方式で配置され、異常の場合、特に事故関連の変形、及び／又は車両シート領域の移動の場合には、安全安全手段が、安全手段に係合し、さらなる変形／移動をブロックするよう相互作用する。安全安全手段（１０）及び安全レール（８）は、係合中においては、通常の車両座標系における軸（Ｘ，Ｙ，Ｚ）の方向に作用する反作用力が、安全レール（８）の２つの異なる係合領域に分布するよう構成される。
Patent JP-2006503124-A (JP)
Title: 少なくとも一つの疎水性基で官能化されたポリアミノ酸、およびその応用、特に治療学的応用
IPC: A61K47/48
Filed: 2003-07-23
Abstract: 本発明は、活性成分（AP）を担持するために有用な、生分解性ポリアミノ酸に基づく新規な材料に関する。本発明の目的は、APを担持するために有用で、且つ生体適合性、生分解性、多くの活性成分と容易に会合する能力、インビボで前記活性成分を可溶化して放出する能力に関する多くの要件を最適に満たす、新規なポリマー材料を提供することである。当該ポリマーはまた、疎水性基のグラフト化率に従って容易に且つ経済的に、活性成分を担持する粒子に変換することができ、該粒子は安定なす異性コロイド懸濁液を形成する。上記の目的は、それぞれが少なくとも一つの疎水性ユニットを含んだグラフトを有するアスパラギン酸ユニットおよび／またはグルタミン酸ユニット含んでなる両親媒性ポリアミノ酸であって、これら疎水性グラフトの少なくとも幾つかが、それぞれ少なくとも二つのアミド結合を含む連結部、特にリジン型またはオルニチン型の「スペーサ」を介して、前記アスパラギン酸および／またはグルタミン酸ユニットに結合されることを特徴とする本発明の両親媒性ポリアミノ酸によって達成される。上記アミド官能基は、従来技術において既知の生成物に比較して、加水分解の際のより良好な安定性を保証する。本発明はまた、本発明のポリアミノ酸に基づく新規な医薬組成物、化粧品組成物、食品組成物または植物衛生組成物に関する。
Patent JP-2005534430-A (JP)
Title: 改良された注射システム
IPC: A61K35/22
Filed: 2003-08-06
Abstract: 側部放出針および、必要に応じて注射部位における細胞の保持を補助するキャリア、または組織封止剤もしくは注射部位を封鎖するためのフィルムを使用して、細胞を含む薬剤を、器官、組織または腫瘍に注射する新規方法が提供される。側部放出針、および必要に応じて、キャリア、封止剤もしくはフィルムの使用は、注射された薬剤の注射部位から逆流する漏出を防止する。本発明の方法を使用して注射され得る薬剤としては、薬物、低分子、ペプチド、タンパク質、ポリヌクレオチド、ウイルス、細胞などが挙げられる。筋芽細胞を含む任意の型の細胞が、本発明中で使用され得る。細胞は、心臓、脳、膵臓、肝臓などを含む任意の器官に注射され得る。これらの注射方法は、組織工学、遺伝子治療および組織／器官修復における利用法を見出し得る。本発明の実施において使用される側部放出針を備えるキットもまた、提供される。
Patent JP-2006504555-A (JP)
Title: アクリル系組成物
IPC: B29K33/00
Filed: 2003-10-29
Abstract: 本発明は、熱成形可能なシートに関し、例えば、上面近傍に位置する粒子を含み、熱成形した際のテクスチャーシートが低光沢性でテクスチャー表面を呈し、傷付き、汚れ（成形型に由来する汚れも包含する）、日常の摩耗および露滴に対する表面の感受性がより小さく、表面上に見える油の付着（例えば指紋）が顕著に低減されるようなアクリル系シートに関する。