baber/WOPTO huggingface dataset:
Patent NZ-228336-A (NZ)
Title: Substituted imidazo (4,5-c) pyridine derivatives and pharmaceutical compositions
Inventor: KHANNA ISH K
IPC: A61P29/00
Filed: 1989-03-14
Abstract: This invention relates to novel substituted imidazopyridine dervatives having the following formula <CHEM>  or a pharmaceuticaly acceptable acid addition salt: wherein R1 and R2      are each independently selected from hydrogen; straight or branched chain alkyl of 1 to 15 carbon atoms; cycloalkyl having 3 to 8 carbon atoms; substituted cycloalkyl which can be substituted one or more by alkyl of 1 to 6 carbon atoms; bicycloalkyl having 3 to 8 carbon atoms in each ring; heterocyclicalkyl having 4 to 8 carbon atoms which can be optionally substituted by alkyl of 1 to 6 carbon atoms; heteroaromatic having 5 or 6 carbon atoms which can be optionally substituted by alkyl of 1 to 6 carbon atoms; phenyl; substituted phenyl which can be substituted one or more by a group independently selected from alkyl of 1 to 6 carbon atoms or halogen; straight or branched alkenyl having 3 to 15 carbon atoms with the proviso that the double bond of the alkenyl group cannot be adjacent to the nitrogen; cycloalkenyl having 5 to 8 carbon atoms with the proviso that the double bond cannot be adjacent to the nitrogen; R1 and R2 cannot both be hydrogen Y      is phenyl or phenyl substituted once or more than at one or more of the 2, 3, 5 or 6 position of the phenyl ring by substituents independently selected from the group consisting of alkoxy wherein the alkyl is 1 to 6 carbon atoms; halogen wherein the halogen is selected from bromo, fluoro, or chloro; straight or brnached chain alkyl having 1 to 6 carbon atoms; substituted straight or branched chain alkyl which can be substituted one or more by halogen; thioalkyl wherein the alkyl is 1 to 6 carbon atoms; alkoxyalkyl wherein the alkyl groups are each 1 to 6 carbon atoms; hydroxyalkyl wherein the alkyl is 1 to 6 carbon atoms; alkylthioalkyl wherein the alkyl group are each 1 to 6 carbon atoms; cyano; mercaptoalkyl wherein the alkyl is 1 to 6 carbon atoms; hydroxy; amino; alkylamino wherein the alkyl group are each 1 to 6 carbon atoms; and dialkylamino wherein the alkyl group are each 1 to 6 carbon atoms.  n      is an integer of 1 to 5. R3      is a group substituted at one or more of the 4, 6, or 7 positions of the pyridine ring said group being independently selected from hydrogen; alkyl of 1 to 6 carbon atoms; halogen wherein the halogen is selected from bromo, fluoro or chloro; alkoxy wherein the alkyl is 1 to 6 carbon atoms.  R4      is hydrogen or alkyl of 1 to 6 carbon atoms. useful in the treatment of diseases or disorders mediated by platelet-activating factor. This invention relates to pharmaceutical compositions of such substituted imidazopyridines.
Patent NZ-231165-A (NZ)
Title: Substituted pyrimidinedione derivatives and pharmaceutical compositions
Inventor: TSUTOMU KATAKAMI
IPC: C07D239/545
Filed: 1989-10-26
Abstract: A pyrimidinedione derivative compound has a basic backbone in which a phenyl group part and a pyrimidinedione part are linked by a structure comprising an alkyl chain containing at least two nitrogen atoms. The pyrimidinedione derivative is useful for a medical treatment of cardiac arrhythmias. The general formula is (1). <CHEM> r
Patent NZ-237079-A (NZ)
Title: Device for connecting a rod to a framework: bolt positioned within rotatable guide sleeve
Inventor: STRASSLE MARCEL
IPC: E04B1/58
Filed: 1991-02-11
Abstract: PCT No. PCT/CH91/00040 Sec. 371 Date Sep. 10, 1991 Sec. 102(e) Date Sep. 10, 1991 PCT Filed Feb. 13, 1991 PCT Pub. No. WO91/12384 PCT Pub. Date Aug. 22, 1991.A guide device including a bolt (5) which through a sleeve insert can be fastened rotatably to one end of a rod (21), which bolt is connected, sliding axially, to the front part of a guide sleeve (16') in such a way that a rotary movement of the guide sleeve (16') can be transmitted to the bolt (5). A spring (20) pushes the bolt (15) out of the guide sleeve (16'), and the rear end of the guide sleeve (16') an approximately bell-shaped flange (17) is provided, which delimits an inside space which is dimensioned such that the head (1) of the sleeve insert can be accommodated therein.
Patent NZ-238495-A (NZ)
Title: N-acyl derivatives of cystine and esters thereof; and pharmaceutical compositions
Inventor: ANDERSSON CARL-MAGNUS ALEXANDE
IPC: A61K31/105
Filed: 1991-06-11
Abstract: New 3,3'-dithiobis(propionic acids) and esters thereof with immunomodulating effect, processes for their preparation, pharmaceutical compositions containing them and methods of their pharmacological use.
Patent NZ-239909-A (NZ)
Title: Anti hiv agents containing glycoprotein cd-4 and dextrin sulphate
Inventor: DAVIES DONALD SELWYN
IPC: A61K38/00
Filed: 1991-09-23
Abstract: The invention provides an agent against HIV and related viruses, in dosage unit form, comprising CD4 or a CD4-like material and a polyanionic anti-HIV agent, the content of CD4 or CD4-like material in the agent being less than the anti-virally effective dose of the CD4 or CD4-like material alone. It has been found that when the CD4 or CD4-like material is used together with a polyanionic anti-HIV agent, the combination is more effective against HIV infection than would be the case if the anti-viral effect was simply additive.
Patent NZ-244456-A (NZ)
Title: Alkoxy substituted taxanes and pharmaceutical compositions
Inventor: HOLTON ROBERT A
IPC: C07F7/00
Filed: 1992-09-23
Abstract: A taxane derivative of the formula <CHEM>  wherein     R<5> is phenyl or substituted phenyl,     R<7> is CH<7>O-, or CH<7>CH<6>O-,     Z is -OT<5>,     T<5> is hydrogen, hydroxyl protecting group, or -COT<6>, T<6> is H, C<5>-C1/4  alkyl, C<5>-C1/4  alkenyl, C<5>-C1/4  alkynyl or monocylic aryl,     Ac is acetyl, and E<5> and E<6> are independently selected from hydrogen and functional groups which increase the water solubility of the taxane derivative are useful as antitumor agents.
Patent NZ-245182-A (NZ)
Title: Preparation of aromatic derivatives of oxazolidinedione and thiazolidinedione using a red yeast reductase; pharmaceutical compositions
Inventor: HINDLEY RICHARD MARK
IPC: A61K31/35
Filed: 1992-11-19
Abstract: A process for preparing a compound of formula (I): <CHEM> or a tautomeric form thereof and/or a pharmaceutically acceptable salt thereof and/or a pharmaceutically acceptable solvate thereof, wherein: T represents a substituted or unsubstituted aryl group and T<1> is O or S; which process comprises, treating a compound of formula (II): <CHEM> or a tautomeric form thereof and/or a salt thereof and/or a solvate thereof, wherein T and T<1> are as defined in relation to formula (I), with a microbial reductase obtained from an appropriate red yeast; and thereafter, as required, preparing a pharmaceutically acceptable salt and/or a pharmaceutically acceptable solvate of the compound of formula (I) or a tautomeric form thereof: compounds prepared by such a process and the use of such compounds in medicine
Patent NZ-285163-A (NZ)
Title: 5-lipoxygenase inhibitors and pharmaceutical compositions
Inventor: STEVENS RODNEY W
IPC: C07D233/60
Filed: 1995-05-29
Abstract: Novel compounds having the ability to inhibit 5-lipoxygenase enzyme and having formula (I) and the pharmaceutically acceptable salts thereof, wherein Ar<1> is a heterocyclic moiety which is selected from imidazolyl, pyrrolyl, pyrazolyl, 1,2,3-triazolyl, 1,2,4-triazolyl, indolyl, indazolyl and benzimidazolyl, which is bonded to X<1> through a ring nitrogen atom, and which may be optionally substituted with one or two substituents selected from halo, hydroxy, cyano, amino, C1-4 alkyl and the like; X<1> is a direct bond or C1-4 alkylene; Ar<2> is phenylene optionally substituted with halo, hydroxy, cyano, amino and the like;  X<2> is -A-X- or -X-A- wherein A is a direct bond or C1-4 alkylene and X is oxy, thio, sulfinyl or sulfonyl; Ar<3> is phenylene, pyridylene, thienylene, furylene, oxazolylene or thiazolylene optionally substituted with one or two substituents selected from halo, hydroxy, cyano, amino, C1-4 alkyl and the like; R<1> and R<2> are each C1-4 alkyl, or together they form a group of formula -D<1>-Z-D<2>- which together with the carbon atom to which it is attached defines a ring having 3 to 8 atoms, wherein D<1> and D<2> are C1-4 alkylene and Z is a direct bond or oxy, thio, sulfinyl, sulfonyl, or vinylene, and D<1> and D<2> may be substituted by C1-3 alkyl; and Y is CONR<3>R<4>, CN, C(R<3>)=N-OR<4>, COOR<3>, COR<3> or CSNR<3>R<4>, wherein R<3> and R<4> are each H or C1-4 alkyl. These compounds are useful in the treatment or alleviation of inflammatory diseases, allergy and cardiovascular diseases in mammals and as the active ingredient in pharmaceutical compositions for treating such conditions.
Patent NZ-289788-A (NZ)
Title: Organic compound monitoring, diffusion cell containing polymeric membrane immersed in a fluid to be monitored
Inventor: BARBER CHRISTOPHER
IPC: G01N30/04
Filed: 1995-07-26
Abstract: PCT No. PCT/AU95/00456 Sec. 371 Date Feb. 10, 1997 Sec. 102(e) Date Feb. 10, 1997 PCT Filed Jul. 26, 1995 PCT Pub. No. WO96/03633 PCT Pub. Date Feb. 8, 1996Environmental monitoring of low concentration of organic compounds in a medium such as ground water or another environmental fluid is effected by using a diffusion cell (112) having a polymeric membrane formed into a helical tube (125) and immersed in the environmental fluid so that organic compounds at ppb and ppt concentrations diffuse into and through the polymeric material. A carrier gas in the polymeric tube acquires a concentration of the organic compounds substantially in equilibrium with the concentration of the organic compounds in the environmental fluid. For the purpose of permitting monitoring with detectors (116) which are not sensitive to extremely low levels of organic compounds, a concentrating device such as a thermal desorption tube (114) can be provided for processing the gas and periodic thermal activation to discharge therefrom organic compounds to be detected at a sensor.
Patent NZ-296285-A (NZ)
Title: Inhibiting physiological conditions associated with bradykinin using a benzothiophene such as raloxifene
Inventor: BRUNS ROBERT FREDERICK JR
IPC: A61K31/55
Filed: 1995-10-19
Abstract: The use of raloxifene of the formula I and hydrochloride salt in the manufacture of a medicament for the inhibiting a physiological condition associated with an excess of bradykinin where; R1 and R3 are H, methyl, CO(C1-6)alkyl, or CO-Ar where Ar is optionally substituted phenyl; R2 is selected from pyrrolidino, hexamethyleneimino and piperidino.
Patent NZ-314176-A (NZ)
Title: Polymer extrusion product, polymer foam-wood flour composite and preparative process
Inventor: COPE CARROLL W
IPC: B29C48/90
Filed: 1997-02-03
Abstract: An extrudable composite comprising a foamable polymer and wood filler suitable for preparing an extruded profile.
Patent NZ-326550-A (NZ)
Title: Pressure-sensitive adhesive composition comprises an acrylic pressure sensitive adhesive suitable for skin and preparation methods
Inventor: WONG ROY
IPC: C08L53/00
Filed: 1996-12-20
Abstract: A pressure-sensitive adhesive composition for medical applications comprising: i)	a blend of at least two components comprised of about 5 to about 95 % by weight of a first component comprised of at least one acrylic pressure-sensitive adhesive and ii)	about 5 to about 95 % by weight of a second component comprised of either (a) at least one elastomer with a tackifying resin, or (b) at least one thermoplastic elastomer wherein the resulting pressure-sensitive adhesive demonstrates a T0 of at least 1 N/dm and a T48 of less than 12 N/dm when adhered to skin is claimed.
Patent NZ-331597-A (NZ)
Title: Process and device for transmitting sound
Inventor: ROCK MICHAEL
IPC: H04R1/10
Filed: 1997-03-06
Abstract: n order to transmit sound to a person, a transducer is arranged in the vicinity of the breastbone of the person to form a direct sound transmission path from the transducer via the eustachian tube to the bones of the middle ear.  This is particularly effective for the transmission of lower frequency sounds.
Patent NZ-332576-A (NZ)
Title: Controlled-release pharmaceutical tablet containing a carrier based on cross-linked amylose and hydroxypropylmethylcellulose
Inventor: CHOUINARD FRANCOIS
IPC: A61K47/36
Filed: 1997-04-04
Abstract: A pharmaceutical tablet for the oral administration with a controlled release of a given amount of at least one active ingredient is claimed. The compound contains up to 60 wt % of active principle mixed and compressed with at least 40 wt % of an amylose carrier cross-linked by means of a cross-linker in an amount of 0.1-10 grams of cross-linker per 100 grams of amylose. The carrier contains 30-90 % of cross-linked amylose and 10-30 % of hydroxypropylmethylcellulose (HPMC) with a viscosity of at least 4000 cps wherein the percentages being by weight relative to the total weight of the tablet.
Patent NZ-334926-A (NZ)
Title: Elastic strand coating process with adhesive fibre substantially captured on strand, and strand applied to substrate, typically as stretched elastic to diapers
Inventor: KWOK KUI CHIU
IPC: B05B7/16
Filed: 1999-03-30
Abstract: Strand 30 is drawn along and separated from substrate 50.  Adhesive fibre 40 is disposed towards strand 30 and vacillated across the path of strand 30.  All of the fibre 40 is captured on strand 30 which is then contacted with substrate 50.
Patent NZ-335147-A (NZ)
Title: Method for controlling parasitic fungi in cultivated plants
Inventor: SCHMIDT RALF-MICHAEL
IPC: A01N37/50
Filed: 1997-10-08
Abstract: The specification describes a method for controlling parasitic fungi in cultivated plants.  The plants have modified pathogenic resistance against certain parasitic fungi.  The cultivated plants are treated with a known active substance from the strobilurin class.
Patent NZ-337408-A (NZ)
Title: Method of manufacturing a cheese flavoured product by fermenting a mixture of a dried protein source, a fat source, an acid source and water
Inventor: BYOD MARY ANN
IPC: A23L27/24
Filed: 1999-08-24
Abstract: A method for producing a cheese-flavored component for use in the manufacture of process cheese comprising: 1. Combining a dried protein source, a fat source, an acid source and water to provide a substrate; 2. Adding an enzyme system comprising a source of protease, a source of peptidase and a source of esterase to the substrate; 3. Treating the substrate with the enzyme system to develop a cheese flavor in the substrate; and 4. Inactivating the enzyme system by heating.
Patent NZ-500521-A (NZ)
Title: Endoscopic pull through cleaning apparatus
Inventor: RODERICK FRANCIS GALANTAI
IPC: A61B19/00
Filed: 1999-10-19
Abstract: This pull through, which is useful as an endoscope cleaning apparatus, comprises: a).a filament having a thermoplastic surface and being a monofilament sufficiently stiff to thread through a passage way; and b).a moulded thermoplastic mass upon the filament defining a pull through profile, where the mass is of a material having a lower melting point than the filament.
Patent NZ-501741-A (NZ)
Title: Process for heat integration of an autothermal reformer and cogeneration power plant
Inventor: KENNEDY CLINTON ROBERT
IPC: C01B3/38
Filed: 1998-06-18
Abstract: A process is disclosed for integration of an autothermal reforming unit and a cogeneration power plant in which the reforming unit has two communicating fluid beds. The first fluid bed is a reformer reactor containing inorganic metal oxide and which is used to react oxygen and light hydrocarbons at conditions sufficient to produce a mixture of synthesis gas, hydrogen, carbon monoxide, and carbon dioxide. The second fluid bed is a combustor-regenerator which receives spent inorganic metal oxide from the first fluid bed and which provides heat to heat the inorganic metal and balance the reaction endotherm, by combusting fuel gas in direct contact with the inorganic metal oxide producing hot flue gas. In preferred embodiments, steam is also fed to the reformer reactor and a catalyst may be used with the inorganic metal oxide. The cogeneration power plant has a gas turbine equipped with an air compressor and a combustor and in the integration a portion of compressed air is drawn off from the power plant gas turbine air compressor leaving remainder compressed air; the drawn off compressed air is introduced to the combustor-regenerator; the hot flue gas from the combustor-regenerator is mixed with the remainder of the compressed air to produce a recombined gas stream and this recombined gas stream is fed to the combustor of the cogeneration gas turbine power plant.
Patent NZ-503013-A (NZ)
Title: Photo-assisted oxidation of inorganic species in aqueous solutions by irridation with UV light
Inventor: ZAW MYINT
IPC: B01J19/12
Filed: 1998-07-22
Abstract: A method for oxidising an inorganic species in an aqueous solution comprises the steps of: (i) supplying an oxidisable source of sulphur, and oxygen to the solution; and (ii) irradiating the solution with UV light such that both the inorganic and sulphur species are oxidised.
Patent NZ-504782-A (NZ)
Title: Board comprising a lignocellulose-based material or an inorganic material and a binder composition comprising a compound having at least two isocyanate groups (or reaction product thereof), LMW polyethylene and water
Inventor: TAKAHASHI AKIHIRO
IPC: C08L97/02
Filed: 1998-10-13
Abstract: A board which comprises a lignocellulose-based material or an inorganic material and a binder composition comprising: i) A compound having at least two isocyanate groups, or a reaction product of a plurality of compounds having at least two isocyanate groups, which compounds are the same or different from each other, or a reaction product of (iv) a monofunctional alcohol having from 80 to 99% of a recurring unit of (-CH2CH2-O-) and a compound having at least two isocyanate groups as a binder component. ii) A low-molecular weight polyethylene having a density at 25oC of from 0.800 to 0.980 and a number average molecular weight of from 500 to 7,000 as a releasing agent. iii) Water as an active hydrogen containing compound necessary for setting component i). The weight ratio of the compound having at least two isocyanate groups or the reaction product thereof (i) to the low molecular weight polyethylene (ii) is in the range of from 1:0.001 to 1:1, and the weight ratio of the compound having at least two isocyanate groups to the lignocellulose or the inorganic material is in the range of from 1:100 to 30:100.
Patent NZ-507440-A (NZ)
Title: Benzazole compounds and their use in insect repellents
Inventor: CHRISTINAZ CATHERINE
IPC: A01N43/78
Filed: 1999-06-16
Abstract: Benzazole compounds of formula (I) are disclosed that may be used in insect-, mite- or tick-repellent compositions, wherein R1 and R2 are the same or different and signify hydrogen, hydroxyl, amino, halogen, C1-C6- alkyl, halogen-C1-C6-alkyl, C2-C6-alkenyl, halogen-C2-C6-alkenyl, C3-C6-cycloalkyl, halogen- C3-C6-cycloalkyl, C1-C6-alkoxy, halogen-C1-C6-alkoxy, unsubstituted phenyl or phenyl which is optionally substituted by halogen or C1-C6-alkyl; nitro, cyano, isothiocyanato, carboxy, C1-C6-alkoxycarbonyl, halogen-C1-C6-alkoxycarbonyl, C1-C6-alkylcarbamido, which is optionally substituted by phenyl or by unsubstituted or halogen-substituted phenoxy; PhNH(CO)NH, C1-C6-alkylsulphonyl, halogen-C1-C6-alkylsulphonyl, unsubstituted or optionally halogen substituted benzoyl; unsubstituted or optionally halogen-substituted phenylthionyl or phenyl- sulphonyl; R3 and R4, independently of one another, are hydrogen, R1, R2 or together are a CH=CH-CH=CH-bridge; X is NR5, O or S; R5 is hydrogen or C1-C6-alkyl; Y is N, CR6 or C=O; R6 is hydrogen, hydroxyl, C1-C6-alkyl, C1-C6-alkylcarbonyl, C1-C6-alkoxy, cyano, 2-di(C1-C6-alkyl)aminoethenyl, (C1-C6-alkyl)NHC(=S) NHCH2, phenyl, thiazolyl, phenylamino, whereby the phenyl group is unsubstituted or optionally substituted by C1-C6-alkoxy; C1-C6- alkylcarbamido, C1-C6-alkoxycarbamido, guanidyl, amino, hydroxy-C2-C6-alkylamino or phenylsulphonylamino, whereby the phenyl group is unsubstituted or optionally substituted by C1-C6-alkyl; Z is N or CR7; and R7 is hydrogen or C1-C6-alkyl.
Patent NZ-507658-A (NZ)
Title: Seat for aircraft with back portion movable between upright and reclined portion and shell behind back portion having lower portion movable to accommodate back portion in reclined position
Inventor: PARK JAMES WILLIAM
IPC: B60N2/90
Filed: 1998-02-18
Abstract: Back shell 30 is located behind the seat. The shell is moved backwards to accommodate the back portion 22, and typically, headrest 24.
Patent NZ-509978-A (NZ)
Title: Removed particles protected against complement mediated destruction
Inventor: GUNZBURG WALTER
IPC: A61K35/12
Filed: 1999-09-23
Abstract: The present invention relates to retroviral particles, which are specifically applicable as safe gene transfer vehicles for targeted gene therapy and which are protected against complement mediated destruction in host organisms. For producing such retroviral particles a packaging cell is provided according to the present invention comprising a DNA construct coding for one or more complement inhibitors. Said inhibitors are derived from the complement system of the organism to be infected by the retroviral particle generated by the packaging cell.
Patent NZ-512448-A (NZ)
Title: Chlamydia antigens and corresponding DNA fragments and uses thereof
Inventor: MURDIN ANDREW D
IPC: A61K48/00
Filed: 1999-12-22
Abstract: A nucleic acid molecule comprising a sequence encoding a polypeptide selected from: a) an ATP/ADP translocase from Chlamydia pneumonia; b) an immunogenic fragment comprising at least 50 consecutive amino acids from a); and c) a polypeptide of a) or b) which has been modified without loss of immunogenicity, which is at least 80% identical in amino acid sequence to the corresponding polypeptide of a) or b). Also covered are uses of said nucleic acid molecule in a vaccine, vector and transformed host, along with a polypeptide produced by said transformed host and uses of said polypeptide in the manufacture of a medicament for the treatment of Chlamydia infection, diagnostic kits, and pharmaceutical compositions.
Patent NZ-513756-A (NZ)
Title: Anti-theft brake or clutch pedal locking device
Inventor: VITO ROBERT A
IPC: B60R25/00
Filed: 2000-03-16
Abstract: A device to lock a brake or clutch pedal (not shown) of a vehicle so as to deter theft of the vehicle includes a base (412) for placement on the floor of the vehicle beneath the pedal of the vehicle being locked and beneath a pedal shaft (not shown) supporting the pedal. The device includes a generally U-shaped housing (414) with a second leg (418) attached to the base (412), a first leg (416) shorter than the second leg, and a cross member (438) connecting the first and second legs to define an opening between the first leg and the base and a slot (422) between the first and second legs to receive the pedal shaft and permit travel of the pedal shaft through the slot (422). A locking mechanism includes a locking pin (426) and a lock (444).
Patent NZ-514648-A (NZ)
Title: Method for the preparation of 1,1,1,3,3- pentafluoropropene and 1,1,1,3,3-pentafluoropropane
Inventor: QIAN JOHN CHENG-PING
IPC: C07C17/00
Filed: 2000-04-05
Abstract: A method for the production of 1,1,1,3,3- pentafluoropropane which comprises contacting 2,2-dichloro- 1,1,1,3,3,3-hexafluoropropane with hydrogen in the presence of a metal-containing catalyst carried by a carbon support, at a temperature from 300oC to about 800oC. The metal-containing catalyst carried by the carbon support is selected from the group consisting of a metal, metal halide, metal oxide, metal oxyhalide and various combinations. Also the metal of the catalyst is selected from the group consisting of Fe, Cu, Ni and Cr.