baber/WOPTO huggingface dataset:
Patent WO-2019126098-A1 (WO)
Title: Acides carbamoyle cyclohexyliques à liaison o pyrazole utilisés en tant qu'antagonistes de lpa
Inventor: CHENG PETER TAI WAH
IPC: A61K31/4427
Filed: 2018-12-18
Abstract: La présente invention concerne des composés de formule (I) ou un stéréoisomère, un tautomère ou un sel pharmaceutiquement acceptable ou un solvate de ceux-ci ; dans la formule, toutes les variables sont telles que définies dans la description. Ces composés sont des inhibiteurs sélectifs de récepteur de LPA.
Patent WO-2019126806-A1 (WO)
Title: Conception et commande d'infrastructure de recharge de véhicule électrique
Inventor: KUMAR ARUN
IPC: B60L53/66
Filed: 2018-12-21
Abstract: L'invention porte sur un système de configuration d'une infrastructure de recharge de véhicule électrique (EV), l'appareil comprenant. Le système reçoit une direction et des entrées d'utilisateur relatives à une infrastructure de recharge d'EV personnalisée, soumet les données à un module de planification optimal qui est configuré pour réaliser une optimisation sur la base d'objectifs au regard d'un ensemble de contraintes ; et génère une recommandation à partir du module de planification optimal pour une infrastructure de recharge d'EV personnalisée sur la base des besoins de recharge et du comportement des consommateurs envers le report de mises à niveau dans l'infrastructure électrique sans faire de concessions sur l'énergie requise pour le transport électrique. Le système valide les résultats du module de planification optimal à l'aide d'un simulateur faisant appel à des événements discrets et génère des programmes de recharge à partir du module de commande permettant une recharge d'EV personnalisée sur la base d'informations concernant des données d'EV, une ressource d'énergie distribuée (DER) et l'infrastructure électrique sans faire de concessions sur l'énergie requise pour le transport électrique et provoquer des effets excessifs sur l'infrastructure électrique.
Patent WO-2019133609-A1 (WO)
Title: Interface for electroencephalogram for computer control
Inventor: LASZLO SARAH ANN
IPC: G06F3/01
Filed: 2018-12-26
Abstract: A method for analyzing electroencephalogram (EEG) signals is disclosed. Information associated with two or more options is presented to a user. EEG signals from a sensor coupled to the user are received contemporaneously to the user receiving information associated with the two or more options. The EEG signals are processed in real time to determine which one of the options was selected by the user. In response to determining which one of the options was selected by the user, an action from one or more possible actions associated with the information presented to the user is selected. An output associated with the selected action is then generated.
Patent WO-2019135999-A1 (WO)
Inventor: HENDRICKS JAMES
IPC: B62D33/07
Filed: 2018-12-28
Abstract: Embodiments of the present invention provide a safety support apparatus for a cabin over engine (COE) truck cabin elevated in a raised position. The safety support apparatus provides a base member having a clamp mechanism which adjusts to truck chassis designs with rails of varying thicknesses. The frame of the safety support apparatus provides a receiver which may engage the bottom of an elevated truck cabin. The frame and base member are adjustable to allow configuration on either side of a truck cabin and deployment of the support apparatus at a range of angles.
Patent WO-2019136305-A1 (WO)
Title: Thérapies à base de cellules et par inhibiteurs de points de contrôle immunitaires combinées à il-12 pour le traitement du cancer
Inventor: BASILE LENA A
IPC: A61K35/15
Filed: 2019-01-04
Abstract: L'invention concerne des méthodes de traitement du cancer à l'aide de l'interleukine-12 (IL-12) dans la génération de thérapies à base de cellules, comprenant des thérapies cellulaires à lymphocyte T de récepteur antigénique chimérique (CAR), de récepteur de lymphocyte T (TCR) modifié, à cellules tueuses naturelles (NK) ou à cellules dendritiques, et l'utilisation d'une combinaison d'interleukine-12 (IL-12) injectable et de telles thérapies à base de cellules, et des compositions les concernant.
Patent WO-2019191157-A1 (WO)
Inventor: PATEL ASHOK
IPC: B26B21/22
Filed: 2019-03-27
Abstract: The invention is directed toward a shaving razor system. The razor system has a handle and a razor cartridge. The handle has at least one skin interconnect member in pivotal relation to a proximal end portion of the handle. The razor cartridge has a housing, at least one blade, and at least one opening which extends through the housing. The razor cartridge is engaged with the skin interconnect member when the skin interconnect member is disposed within the opening securing the razor cartridge to the proximal end portion of the handle. The razor cartridge is in a pivotal relation with the handle, but not with the skin interconnect member. A pivot point of the razor system is desirably disposed near the front blade of the cartridge. Axes of movement in the razor system can be provided by different physical order of connections of razor components.
Patent WO-2019191165-A1 (WO)
Title: Manche de rasoir comprenant une partie pivotante
Inventor: VERASAMY MICHAEL
IPC: B26B21/44
Filed: 2019-03-27
Abstract: L'invention concerne un manche. Le manche peut avoir un corps principal et une tête pivotante (22) accouplée de façon pivotante au corps principal autour d'un axe de pivot. La tête pivotante peut avoir une forme de prisme sensiblement trapézoïdal et comprendre un élément base (42) et un élément couvercle (40) qui recouvre l'élément base dans une relation d'accouplement. L'élément couvercle peut comprendre une face définissant au moins une ouverture extérieure et la tête pivotante peut avoir un compartiment intérieur en communication fluidique avec le corps principal et l'ouverture extérieure.
Patent WO-2019195509-A1 (WO)
Title: Gated asynchronous multipoint network interface monitoring system
Inventor: CLEMENS STEVEN
IPC: G05B23/02
Filed: 2019-04-04
Abstract: Systems, methods, and devices for monitoring operation of industrial equipment are disclosed. In one embodiment, a monitoring system is provided that includes a passive backplane and one more functional circuits that can couple to the backplane. Each of the functional circuits that are coupled to the backplane can have access to all data that is delivered to the backplane. Therefore, resources (e.g., computing power, or other functionality) from each functional circuits can be shared by all active functional circuits that are coupled to the backplane. Because resources from each of the functional circuits can be shared, and because the functional circuits can be detachably coupled to the backplane, performance of the monitoring systems can be tailored to specific applications. For example, processing power can be increased by coupling additional processing circuits to the backplane.
Patent WO-2019200055-A1 (WO)
Title: Sugar dispenser with auger
Inventor: Bertness Elizabeth
IPC: A47J31/40
Filed: 2019-04-11
Abstract: Systems and apparatus for dispensing edible granular material for a beverage include a hopper. The hopper includes at least a floor defining a bottom of the hopper. An auger includes an auger shaft, is positioned at the bottom of the hopper, and extends horizontally from the hopper. A tube is connected to the hopper and surrounds at least a portion of the auger. The tube extends away from the hopper. An outlet through the tube is located at an end of the tube distal from the hopper.
Patent WO-2019213610-A1 (WO)
Title: Natural killer cells engineered to express chimeric antigen receptors with immune checkpoint blockade
Inventor: DAHER MAY
IPC: C07K14/54
Filed: 2019-05-03
Abstract: Provided herein are methods for producing NK cells expressing chimeric antigen receptors and having no expression of CISH. Further provided are methods for treating diseases by administering the CAR NK cells.
Patent WO-2019221940-A1 (WO)
Title: Device identification on a building automation control network
Inventor: STANCIU ALINA MIHAELA
IPC: H04L12/28
Filed: 2019-05-06
Abstract: Discovering devices and device configurations. A method includes sending a request to a device to obtain a data value from the device. The method further includes, in response, receiving the data value from the device. The method further includes, based on the received data value, identifying one or more device identifications for the device. The method further includes, using the one or more identifications, sending commands for equipment potentially connected to the device. The method further includes, receiving one or more responses to the commands. The method further includes, based on the one or more responses, concretely identifying the device
Patent WO-2019217689-A1 (WO)
Title: Energy storage and power output flywheel system
Inventor: BAKHOLDIN DANIEL
IPC: H02K7/02
Filed: 2019-05-09
Abstract: An improved flywheel system for storing energy and providing the stored energy includes a rotor on a centrally located shaft. The shaft is positioned through support bearings. A magnetic off-loader provides a magnetic force to move the shaft axially in regard to the bearings. A feedback control system, provided to reduce bearing loads on the bearing, comprises a sensor mounted in a bearing housing positioned to measure the distance of a gap between a top end of the shaft and a lower surface of the sensor. In response to changes in the distance the sensor sends an electrical signal to a controller which in turn provides variable electric current to the magnetic off-loader which then provides a magnetic lifting force to the rotor on the shaft to minimize bearing load.
Patent WO-2019240914-A1 (WO)
Title: COMPUTING SYSTEM PROVIDING ENHANCED POINT OF PRESENCE (PoP) SERVER SELECTION BASED UPON NETWORK HEALTH METRICS AND RELATED METHODS
Inventor: SRIVATSAN KARTHICK
IPC: H04L12/24
Filed: 2019-05-21
Abstract: A computing system may include point of presence (PoP) servers coupled to a wide area network (WAN) and configured to receive client requests for a Software as a service (SaaS) application(s) from different network branches coupled to the WAN, and connect the network branches with a given SaaS host server from among different SaaS host servers coupled to the WAN and providing the SaaS application(s). The system may also include a PoP selection controller (PSC) coupled to the WAN and cooperating with the PoP servers to determine first network health metrics for connections between the PoP servers and the network branches, determine second network health metrics for connections between the PoP servers and the SaaS host servers, and select a respective PoP server for each network branch to be connected with for providing the SaaS application(s) based upon the first and second network health metrics.
Patent WO-2019232040-A1 (WO)
Title: Micro-coil wristband
Inventor: ANDERSON GREGORY S
IPC: A61N2/08
Filed: 2019-05-29
Abstract: An erythrocyte (70) aggregation (72) remediation or de-aggregation system (10) includes a band (12), including a strap (20) and housing (14) securing (88) an iron-cored (62), micro-coil (40) to an appendage, such as a wrist, of a subject to apply (96) a PEMF into target vessels in the vascular system of the subject. Typically, all of the blood circulates about the body within a matter of a few minutes, some within seconds, thus treating the entire bloodstream over time. The portable PEMF system (10) intensifies both the concentration of electromagnetic flux per unit area, as well as the depth of penetration into the body. The portable PEMF system (10) relies on the body's circulatory system to eventually pass the body's entire volume of blood past it over a period of time.
Patent WO-2019232137-A1 (WO)
Title: Bite-actuated mouthpieces and drink vessels including bite-actuated mouthpieces
Inventor: CAMPBELL DEREK
IPC: B65D47/20
Filed: 2019-05-30
Abstract: Bite-actuated mouthpieces and drink vessels including bite-actuated mouthpieces are disclosed. Bite-actuated mouthpieces comprise a body comprising a dispensing wall, one or more sidewalls extending from the dispensing wall that with the dispensing wall define an internal volume, and an inlet to the internal volume. The self-sealing exit is biased toward a closed configuration and is configured to be selectively reconfigured from the closed configuration to an open configuration responsive to user-applied compressive forces to opposing bite regions. The dispensing wall has a dispensing face opposite the internal volume, and in some examples, the dispensing face is concave.
Patent WO-2019246142-A1 (WO)
Inventor: CHEN HAIMING
IPC: A61K39/00
Filed: 2019-06-18
Abstract: A bispecific fusion protein agent may include at least one binding site with human IgG1 hinge that specifically binds to a function protein and at least another one binding site with human IgG1 hinge that specifically binds to a different function protein. For example, the bispecific fusion protein agent can be a bispecific fusion protein agent PD-1/LAG-3 that includes a biding site of the human IgGl hinge that specifically crosslinks to a LAG-3 molecule, and another binding site of the human IgG1 hinge that specifically crosslinks to a PD-1 molecule.
Patent WO-2020006256-A1 (WO)
Title: Lighting control network and associated method
Inventor: AHMAD RIZWAN
IPC: H05B37/02
Filed: 2019-06-27
Abstract: The present disclosure is directed to examples of a lighting data network. In one embodiment, the lighting data network includes a first luminaire, comprising a first wireless communication interface to receive data from a machine and a second luminaire, comprising a second wireless communication interface to receive the data from the first luminaire and a third communication interface to transmit the data to a third party control system.
Patent WO-2020018488-A1 (WO)
Title: Robust nitric oxide-releasing polymers and articles and methods of making and uses thereof
Inventor: HANDA HITESH
IPC: A61L29/16
Filed: 2019-07-16
Abstract: Described herein are nitric oxide releasing materials, methods of making nitric oxide releasing materials, and devices including nitric oxide releasing materials. The nitric oxide releasing material includes a polymer matrix having a plurality of polysiloxanes and nitric oxide-donating crosslinking moieties that covalently crosslink the polysiloxanes. Blood clotting or adhesion of a biomaterial to a surface, as well as biofilm formation can be prevented using the methods and materials described.
Patent WO-2020028372-A1 (WO)
Title: Repetition techniques for autonomous uplink transmissions
Inventor: SUNDARARAJAN JAY
IPC: H04L1/08
Filed: 2019-07-30
Abstract: Methods, systems, and devices for wireless communications are described that provide improved repetition techniques for autonomous uplink transmissions. Configuration information may be provided from a base station to a user equipment (UE) for autonomous uplink transmissions, that may indicate initial resources for an initial uplink transmission slot and retransmission resources for a number of retransmissions. Time resources within the retransmission resources may be configured to provide enhanced reliability, such as by being configured in non-contiguous slots to avoid one or more other transmission channels. Time resources within slots may also be configured to prevent persistent collisions with autonomous uplink transmissions or retransmissions of two or more different UEs.
Patent WO-2020028739-A1 (WO)
Title: Body part motion analysis using kinematics
Inventor: GONG NAN-WEI
IPC: A61B5/11
Filed: 2019-08-02
Abstract: Disclosed embodiments describe techniques for body part motion analysis using kinematics. Two or more sensors, which include stretch sensors or inertial sensors, are attached to a body part of an individual. The two or more sensors enable collection of motion data of the body part. Data is collected from the two or more sensors, where the two or more sensors provide electrical information based on a micro-expression of movement of the body part. One or more processors are used for analyzing the electrical information from the two or more sensors to generate a kinematic phase pattern. The kinematic phase pattern is rendered as part of a kinematic sequence, where the rendering is displayed visually. The rendering includes an animation and enables additional kinematic analysis. The two or more sensors capture two or more modalities of body part motion.
Patent WO-2020036812-A1 (WO)
Title: Activators of the retinoic acid inducible gene "rig-i" pathway and methods of use thereof
Inventor: BEDARD KRISTIN
IPC: A61K31/429
Filed: 2019-08-09
Abstract: The present invention is directed to compounds of Formula (I), which are activators of the RIG-I pathway.
Patent WO-2020041270-A1 (WO)
Title: Collections of peptides, peptide agents, and methods of use thereof
Inventor: MCGEE JOHN
IPC: A61K38/00
Filed: 2019-08-20
Abstract: The present disclosure provides powerful technologies for the development, production, characterization, and/or use of stapled peptide compositions. Among other things, the present disclosure provides strategies for defining amino acid sequences particularly amenable or useful for stapling, as well as technologies, reagents, and systems for developing, producing, characterizing, and/or using stapled peptides having such amino acid sequences.
Patent WO-2020041322-A1 (WO)
Title: Novel cannabinoids and cannabinoid acids and their derivatives
Inventor: BERKOWITZ BARRY
IPC: C07C37/00
Filed: 2019-08-20
Abstract: The present invention relates to novel cannabinoids 1 and 2, synthesized from simple starting materials using a cascade sequence of allylic rearrangement, aromatization and, for tetracyclic cannabinoids, further highly stereoselective and regioselective cyclization. These synthesized cannabinoids can more easily be obtained at high purity levels than cannabinoids isolated or synthesized via known methods. The cannabinoids 2 are obtained containing very low levels of isomeric cannabinoids such as the undesirable Δ8- tetrahydrocannabinol. The analogues with variation in aromatic ring substituents, whilst easily synthesized with the new methodology, would be much more difficult to make from any of the components of cannabis oil. Novel compounds of the formulas 3, 4, 5 and 6, as intermediates for the synthesis of the cannabinoids of the formulas 1 and 2 are also disclosed.
Patent WO-2020046871-A1 (WO)
Inventor: MAHAJAN MANOJ
IPC: E21B44/00
Filed: 2019-08-27
Abstract: A bit used in a downhole environment has an active element that is movable relative to the bit. The bit is rotated in the downhole environment, and at least one downhole parameter is measured. The at least one downhole parameter is compared against a target parameter value, and when the at least one downhole parameter is beyond a threshold value of the target parameter value, the active element is selectively relative to the bit. Movement of the active element alters the proportion of the weight on the active element as compared to the other cutting structure of the bit. Changing the proportion of weight can be used to reduce the depth of cut of the cutting structure and to reduce or eliminate motor stall or stick-slip behavior.
Patent WO-2020051372-A1 (WO)
Title: Using ephemeral url passwords to deter high-volume attacks
Inventor: FRANCO JOHN
IPC: H04L29/06
Filed: 2019-09-05
Abstract: Methods and systems for using ephemeral URL passwords to deter high volume attacks is described. A request to access one of several protected URLs is detected from a client computing device. A URL password is received from the client computing device. The request is redirected to the protected URL upon determining that the received URL password is valid for the one of the several of protected URLs.
Patent WO-2020051472-A1 (WO)
Title: Coordinated energy outputs of separate but connected modules
Inventor: HENDERSON JOSHUA
IPC: H02J3/46
Filed: 2019-09-06
Abstract: Aspects of the present disclosure are presented for providing coordinated energy outputs of separate but connected modules, in some cases using communication protocols such as the Data Distribution Service standard (DDS). In some aspects, there is provided a communication circuit between a header or main device, a first module, and a second module, each including connection to a segment of a common backplane, where the output from a first module can be adjusted by sensing a parameter from a second module. In some aspects, the signal can pass from the first module through the header to the second module, or in other cases directly from the first module to the second module. Aspects of the present disclosure also include methods for automatically activating a bipolar surgical system in one or more of the modular systems using the DDS standard.
Patent WO-2020055751-A1 (WO)
Title: A method for intelligent multi-hop overlay routing
Inventor: BERNARDI GIACOMO
IPC: H04L45/24
Filed: 2019-09-09
Abstract: Systems and methods are presented herewith for selecting a preferred route for routing a packet from a first network node to a second network node. A set of possible routes is maintained, with each route having am associated weight value. A random subset of routes is then selected based on the weight values. Each route of the subset is then probed to determine its gain value. The preferred route is selected based on the gain values (e.g., by selecting the highest gain value). Then, all weight values are updated based on the respective gain values. The steps are periodically repeated. Then, whenever a packet needs to be routed, the route currently designated as preferred is used.
Patent WO-2020086187-A1 (WO)
Inventor: ZHUO HAIZHEN
IPC: G06F16/25
Filed: 2019-09-13
Abstract: L'invention concerne des procédés, des systèmes et des dispositifs, y compris des programmes informatiques codés sur des supports de stockage informatiques, destinés au traitement de données. L'un des procédés consiste : à recevoir un paramètre d'interrogation; à obtenir des données de résultat d'interrogation à partir de chacune des sources de données prédéfinies en fonction du paramètre d'interrogation; à convertir les données de résultat d'interrogation en données fiables cibles conformes à un protocole de fiabilité de données prédéfini; et à envoyer les données fiables cibles à un nœud de chaîne de blocs.
Patent WO-2020081280-A1 (WO)
Title: A coating composition, a coated fabric, a method of making a coated fabric, and an article made from the coated fabric
Inventor: GORIN CRAIG
IPC: C09D5/00
Filed: 2019-10-08
Abstract: A coating composition which comprises a first polymeric component which comprises a first polymeric dispersion, wherein polymers contained in the first polymeric dispersion have a surface free energy of equal to or greater than 28 mJ/m 2  and a volume average particle size diameter of from 0.1 to 10 microns; a second polymeric component which comprises one or more second polymeric emulsions wherein polymers contained in the second polymeric emulsions have a surface free energy equal to or less than 26 mJ/m 2  and a volume average particle size diameter from 0.005 to 1,000 microns; one or more rheology modifiers is provided. An article coated with the coating composition and a method of making the coated article are also provided.
Patent WO-2020076775-A1 (WO)
Inventor: DEHART JASON
IPC: C12N15/86
Filed: 2019-10-08
Abstract: The invention provides RNA replicons useful for administering a heterologous protein or peptide into a mammal and eliciting a reduced immune response or no immune response from the mammal. The RNA replicons have RNA sequences encoding for a heterologous protein or peptide, New World alphavirus nonstructural proteins nsP1, nsP2, and nsP4; and an alphavirus nsP3 protein macro domain, central domain, and hypervariable domain. The encoded hypervariable domain can have an amino acid sequence derived from an Old World alphavirus nsP3 hypervariable domain; or can have an amino acid sequence derived from a portion of a New World alphavirus nsP3 hypervariable domain, and another portion derived from an Old World alphavirus nsP3 hypervariable domain.