baber/WOPTO huggingface dataset:
Patent NZ-233192-A (NZ)
Title: Counterflow heat exchanger with a serpentine flow path
Inventor: URCH JOHN FRANCIS
IPC: F24F12/00
Filed: 1990-04-03
Abstract: A heat exchanger is constructed from a heat -conductive metal foil wound backwards and forwards in sinuous fashion to provide a stack of parallel pockets (1) between neighboring sections (8) of the foil. The pockets (1) contain baffles (5,6) which guide fluid flowing through the pockets to follow a serpentine path of U, S or M shape. The serpentine path in all the pockets is substantially the same shape but the direction of fluid flow (13) in alternate pockets is opposite to the flow direction (14) in the remaining pockets. Two corner regions of the pocket stack are each provided with two manifolds (15,16) one of which communicates with the alternate pockets (1) and the other manifold communicates with the remaining pockets (16). The pockets may be formed from a single foil or from two or more foils. The manifolds may be arranged on diagonally opposite, or on adjacent corner regions of the stack.
Patent NZ-233558-A (NZ)
Title: Preparation of a fast release stabilised aspartame ingredient for chewing gum
Inventor: ZIBELL STEVEN E
IPC: A23L27/30
Filed: 1990-05-04
Abstract: A process is disclosed for making a chewing gum with a fast release, stabilized chewing gum. According to the method, a quantity of aspartame (APM) is mixed with an agglomerating agent, such as a modified cellulose, and a limited quantity of a solvent for the agglomerating agent, such as water. The quantity of solvent is limited so as to produce a mixture which is only moist or damp. This damp mixture is characterized as being dust-free, non-flowing and crumbly. The damp mixture is then dried and the dried mixture is comminuted, e.g. by grinding, to produce particles of APM ingredient with essentially a maximum particle size of about 0.017 inches. These particles of APM ingredient are then added to a chewing gum formulation.
Patent NZ-240438-A (NZ)
Title: Process for the preparation of phenoxy-substituted pyrimidines; products of the process
Inventor: JONES JOHN DAVID
IPC: C07D311/12
Filed: 1991-11-01
Abstract: Processes for the preparation of compounds (X), (XI) and (XII): <CHEM>   <CHEM>   <CHEM> where M is an alkali metal or alkaline earth metal and n is 1 or 2, and for obtaining compound (X) in a substantially pure form. These compounds are useful intermediates in the manufacture of fungicides.
Patent NZ-243524-A (NZ)
Title: Insulated sandwich roof panel: outer skin forms an imperforate joint drainage channel with upturned edge on one longitudinal panel edge and forms an overlap on the other: "pockets" in insulation for panel fastenings and end overlap coupling
Inventor: SERRANO MARTIN JOSE ANTONIO
IPC: E04D3/35
Filed: 1992-07-10
Abstract: It comprises panels (1) with the longitudinal sides configured for lateral engagement of the panels, which present a drainage channel (5) hidden by a jut (8) of the panel immediately beside it. The channel (5) collects possible infiltrations through the joints (22) arranged between the panels coupled laterally. The panels present a slot (18) on one end and an extension (19) on the opposite end, which couple together, by overlapping and axial sliding. The panels have a space (3a) in which is arranged a securing staple (24) which secures the panels to a support structure (30). This staple is spaced apart from the channel (5) and hidden by the jut (8) of the next lateral panel, so that the securing devices are isolated from the outside. One of the ends (116) of the panels (101) has a cross section of smaller dimensions than the rest of the panel, so that it can be couple by longitudinal sliding inside a slot (118) of complementary form made at the other end of the panels. Total watertightness is obtained, without need to use weather strips and inner seals. <IMAGE>
Patent NZ-244493-A (NZ)
Title: Stabilised composition containing continuous non-aqueous liquid phase, dispersed organic particles and a stabiliser; bituminous compositions and preparatory methods
Inventor: HESP SIMON
IPC: C08L95/00
Filed: 1992-09-25
Abstract: Insoluble particulate materials, which may be in solid or liquid form, are dispersed in a continuous non-aqueous phase and the dispersion rendered stable and resistant to phase separation by an in-situ stabilization procedure involving the formation of chemical bonds among the stabilizer components and to dispersed phases to form a network surrounding the particles which is compatible with the continuous phase. The invention has particular application for the formation of stabilized polyolefin-modified bitumen compositions for paving and other applications.
Patent NZ-264536-A (NZ)
Title: Soft gelatine capsules with a migrateable solvent in the capsule filling.
Inventor: BROX WERNER
IPC: A61K9/48
Filed: 1994-09-26
Abstract: Soft gelatin capsules having a capsule shell comprising gelatin, plasticizers and, if desired or required, further auxiliary agents, and a capsule filling containing a solvent including a migrateable solvent such as 1,2-propyleneglycol as a solvent in the capsule filling and in the capsule shell. The manufacture of said capsules is improved, if in the process for making the soft gelatin capsules the gelatin bands are cooled with a liquid, and preferably with water.
Patent NZ-264682-A (NZ)
Title: Galanthamine derivatives and medicaments therof
Inventor: KOSLEY RAYMOND W
IPC: C07D223/02
Filed: 1994-10-13
Abstract: This application relates to compounds of the formula <CHEM> wherein R<1>, R<2> and R<3> are defined within, which compounds are useful for the treatment of memory dysfunction characterized by decreased cholinergic function, pharmaceutical compositions containing the compounds and methods for making and using the compounds.
Patent NZ-277290-A (NZ)
Title: Replacement cartridge for a powder inhalator has doses dispensed from helically arranged compartments
Inventor: EASON STEPHEN WILLIAM
IPC: A61M15/00
Filed: 1994-12-09
Abstract: PCT No. PCT/GB94/02716 Sec. 371 Date Aug. 29, 1996 Sec. 102(e) Date Aug. 29, 1996 PCT Filed Dec. 9, 1994 PCT Pub. No. WO95/16483 PCT Pub. Date Jun. 22, 1995A device for dispensing doses of powdered material comprises a housing which houses a cylindrical container. The container has a number of helically arranged compartments each of which contains a respective dose of powdered material. In order to dispense the material from a compartment, that compartment is moved into registry with an airway in the device by means of an indexing mechanism, and the user sucks on a mouthpiece of the housing, which mouthpiece communicates with an air inlet via the airway. The flow of air through the airway ejects the dose of material. The container can constitute a replaceable cartridge. The device is particularly suitable for use as an inhaler for dispensing powdered medicament.
Patent NZ-284048-A (NZ)
Title: Foam generating and metering appliance, return stroke of piston sucks residual foam back into outlet channel
Inventor: REIDEL HERMANN
IPC: A45D27/10
Filed: 1995-04-24
Abstract: PCT No. PCT/DE95/00547 Sec. 371 Date Nov. 1, 1996 Sec. 102(e) Date Nov. 1, 1996 PCT Filed Apr. 24, 1995 PCT Pub. No. WO95/29759 PCT Pub. Date Nov. 9, 1995The invention relates to a device for generating and metering foam, especially foamed soap. To prevent further dispensing of drips of residual foam in a foam outlet channel after the quantity required has been supplied, the device is constructed in such a way that the underpressure subsisting on the return stroke of a piston in an air chamber is effective in the foam outlet channel and sucks residual foam back.
Patent NZ-290029-A (NZ)
Title: Antifungal-wound healing composition comprising an antifungal agent, a pyruvate and antioxidant and a mixture of fatty acids
Inventor: MARTIN ALAIN
IPC: A61K8/365
Filed: 1995-07-07
Abstract: This invention pertains to therapeutic antifungal-wound healing compositions. The compositions comprise a therapeutically effective amount of an antifungal agent and a wound healing compositions. In one embodiment the wound healing composition comprises (a) pyruvate; (b) an antioxidant; and (c) a mixture of saturated and unsaturated fatty acids. The therapeutic antifungal-wound healing compositions may be utilized in a wide variety of topical and ingestible pharmaceutical products. This invention also relates to methods for preparing and using the therapeutic antifungal-wound healing compositions and the pharmaceutical products in which the compositions may be used.
Patent NZ-292260-A (NZ)
Title: Dried foamed lipid deposit; its use for making liposomes (for diagnostic contrast compositions)
Inventor: TOURNIER HERVE
IPC: A61K9/127
Filed: 1995-09-28
Abstract: The invention relates to a dry deposit as a precursor to liposome vesicles, the precursor being a three dimensional expanded structure with bulk density between 0.01 and 0.001 g/cm3. The invention also concerns a method of making liposome vesicles with an enhanced entrapment capacity by dissolving one or more film forming lipids in at least one organic solvent to form a solution in a reaction vessel, evaporating the solvent to form an expanded three dimensional porous lipid structure, contacting the lipid deposit with an aqueous carrier phase, and producing liposome vesicles entrapping the carrier phase as well as an apparatus comprising an array of tubing or an inert packing which serves as a material support or a matrix surface for the deposition of lipids produced according to the method.
Patent NZ-296087-A (NZ)
Title: Interference-suppressing reagent specific to certain classes of antibodies
Inventor: SCHLIEPER DITTMAR
IPC: C07K16/06
Filed: 1995-11-02
Abstract: PCT No. PCT/EP95/04307 Sec. 371 Date Apr. 24, 1997 Sec. 102(e) Date Apr. 24, 1997 PCT Filed Nov. 2, 1995 PCT Pub. No. WO96/14337 PCT Pub. Date May 17, 1996The invention concerns a composition composed of several different antibodies or/and antibody fragments which is suitable as a reagent to reduce interferences in an immunological method for the class-specific detection of antibodies from one or several of the immunoglobulin classes G, M, A, D and E.
Patent NZ-313686-A (NZ)
Title: Methods for determining the coat colour genotype of a pig
Inventor: ANDERSSON LEIF
IPC: C12Q1/68
Filed: 1996-07-24
Abstract: A method of determining the coat colour genotype of a pig comprising obtaining a sample of pig nucleic acid and analyzing he nucleic acid to determine whether duplication of all or part of the KIT gene is present is claimed.
Patent NZ-314991-A (NZ)
Title: Preparation of cephem and isooxacephem derivatives using a thiophosphoric/carboxylic anhydride for acylation; 2-aminothiazolyl substituted diethoxy-phosphoryl ester intermediate
Inventor: OBERHAUSER THOMAS
IPC: C07D501/00
Filed: 1997-06-03
Abstract: process for the preparation of compounds of formula (I) is claimed wherein: R1 is trityl, acetyl, tetrahydropyranyl or cyclopentyl; R2 is hydrogen, hydroxy or an optionally substituted lower alkyl, cycloalkyl, lower alkoxy, lower alkenyl, lower alkynyl, aryl, aryloxy, aryl-lower alkyl, aryl-lower alkoxy or heterocyclyl or heterocyclyl-lower alkyl; Y is -S- and Z is -CH2- or Y is -CH2- and Z is -O-; by acylation of a compound of formula (II) with an activated carboxylic acid derivative of formula (III). Also claimed are the compounds of formula (III) wherein R3 is lower alkyl, and R1, R2, X, Y, Z have the significance given above.
Patent NZ-326284-A (NZ)
Title: Promoter from tobacco to control the expression of exogenous DNA in plant species
Inventor: FOBERT PIERRE
IPC: C12N15/82
Filed: 1997-01-31
Abstract: -DNA tagging with a promoterless b-glucuronidase (GUS) gene generated a transgenic Nicotiana tabacum plant that expressed GUS activity constitutively  The gene fusion has been cloned and sequenced.  It has been re-inserted into N.tabacum by Agrobacterium-mediated transformation. The N.tabacum DNA upstream from the GUS gene was approximately 2 kb in length and showed no homology to known sequences.  This DNA, which contains a constitutive promoter, is useful in controlling the expression of exogenous genes in transgenic plants of diverse plant species.
Patent NZ-331527-A (NZ)
Title: Acoustic wave testing of logs for selection of wood based on fibre characteristics
Inventor: ALBERT DENIS JOHN
IPC: G01N29/04
Filed: 1999-08-24
Abstract: A method for predictively assessing one or more characteristics of wood fibre or wood pulp produced from solid wood is disclosed.  The method includes determining the velocity of sound through the solid wood and assessing characteristics(s) of wood fibre or wood pulp produced from the wood by reference to the velocity through the solid wood.  An apparatus for carrying the method is also claimed.  The apparatus includes sensing mean capable of detecting the velocity of a sound wave through the length of wood and computer processing means comprising stored information on fibre characteristic(s) versus sound velocity through wood and arranged to determine the fibre characteristic(s) for the wood by reference to the stored information on fibre characteristics versus velocity through the wood.
Patent NZ-332995-A (NZ)
Title: A protein which binds to osteoclastogenesis inhibitory factor (OCIF)
Inventor: YAMAGUCHI KYOJI
IPC: A61K/
Filed: 1998-04-15
Abstract: The protein OBM (OCIF-binding molecule) binds to osteoclastogenesis inhibitory factor (OCIF) and exhibits high affinity to OCIF. This protein has a molecular weight of 30,000-40,000 Da and an apparent weight of 90,000-110,000 when crossed linked to a monomer type OCIF. The protein exhibits activity supporting or promoting osteoclast differentiation and maturation in a co-culture system of the osteoblastic stromal cells and spleen cells in the presence bone resorption stimulating factors. A pharmaceutical composition for the treatment of bone metabolism disorders is also described.
Patent NZ-336511-A (NZ)
Title: Treating prostatic diseases using delayed and/or sustained release formulations of activated vitamin D
Inventor: BISHOP CHARLES W
IPC: A61K33/243
Filed: 1997-12-10
Abstract: Provided is a method of treating prostatic conditions such as prostate cancer and hyperplasia by administering 1a-hydroxyprevitamin D or activated vitamin D or a combination thereof in either a sustained release form or a delayed and sustained release formulation.  Both the sustained release form and the delayed, sustained release form deliver increase active vitamin D blood levels without significant risk of hypercalcemia associated with other oral dosing of vitamin D forms, to provide the beneficial effect to the diseased prostate tissue.
Patent NZ-337647-A (NZ)
Title: Preparation of 4-cyano-4'-hydroxybiphenyl by Friedel-Craft alkylation reaction
Inventor: CAZAUX JEAN-BERNARD
IPC: C07C255/53
Filed: 1998-02-16
Abstract: The invention relates to a preparation process for 4-cyano-4'hydroxybiphenyl, said process comprising the protection of the hydroxy group of 4-phenyl-phenol, acylation of the protected 4-phenyl-phenol group by the Friedel Crafts reaction, conversion of the resulting ketone into an acid, amidification of the acid thus obtained, dehydration of the resulting amide and deprotection of the hydroxy group.
Patent NZ-337654-A (NZ)
Title: A controlled pharmaceutical comprising a viscoelastic polymer (hyaluronic acid), and an anesthetic agent (lidocaine) and optionally a drug (a mitotic or mydriatic agent) for delivery to the anterior chamber of the eye
Inventor: GALIN MILES A
IPC: A61K31/46
Filed: 1998-03-18
Abstract: A composition for use in ophthalmology surgery comprising a viscoelastic polymer, an anesthetic agent, and a drug, wherein the viscoelastic polymer, the anesthetic agent, and the drug form an ionic viscoelastic polymeranesthetic-drug complex, wherein the drug is selected from the group consisting of miotic and mydriatic agents. The miotic and mydriatic agents are selected from the group consisting of atropine, pilocarpine, phenylephrine, isopilocarpine, acetylcholine, atropine sulfate, pilocarpine hydrochloride, phenylephrine hydrochloride, acetylcholine chloride, pilocarpine hydrochloride, and isopilocarpine hydrochloride. The anesthetic agent is selected from the group consisting of lidocaine, proparacaine, tetracaine, phenacaine, naepaine, cocaine, betoxycaine, bupivacaine, butacaine, butanilicaine, butoxycaine, carticaine, cyclomethycaine, dibucaine, dimethocaine, etidocaine, formcaine, hexylcaine, hydroxytetracaine, leucinocaine, mepivacaine, meprylcaine, metabutoxycaine, myrtecaine, octacaine, orthocaine, oxethazine, parethoxycaine, piperocaine, piridocaine, pirilocaine, procaine, propanocaine, propipocaine, propoxycaine, pseudocaine, pyrrocaine, ropivacaine, tolylcaine, tricaine, and trimecaine.
Patent NZ-500992-A (NZ)
Title: Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia
Inventor: JOLLIFFE LINDA
IPC: C07D223/10
Filed: 1998-05-08
Abstract: A series of arylsubstituted piperazines, of Formula (I), pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds selectively inhibit binding to the ¹-1a adrenergic receptor, a receptor which has been implicated in benign prostatic hyperplasia.  In addition, these compounds reduce intraurethral pressure in an in vivo model.  As such the compounds are potentially useful in the treatment of this disease.
Patent NZ-501824-A (NZ)
Title: Apparatus and method for routing telecommunications between two terminals along a preferred route
Inventor: HILSENRATH MICHAEL
IPC: H04M1/26
Filed: 1998-07-17
Abstract: Telephone calls are routed by means of a routing device which prefixes user generated call numbers with a prefix code which determines a network connection route and provides billing and customer identification information. The device determines the preferred route by addressing a look up table (134, 135) which is periodically updated with updating information transmitted via radio broadcast from a control centre. The device may be a stand alone device connected intermediate a telephone and a local exchange connection or may be formed unitarily with a telephone, facsimile machine or mobile telephone. The broadcast updating information is transmitted by a message pager transmitting system during off peak message handling times. The device is provided with two memory areas for first and second look up tables (134, 135) so that one of the tables remains addressable while the other one of the tables is being updated with updating information, the most recently updated table being subsequently used as a decision table.
Patent NZ-501955-A (NZ)
Title: Fire rated flush box for insertion into existing electrical flush box
Inventor: CHERRIE RICHARD ELLIOT
IPC: H02K5/06
Filed: 1999-12-17
Abstract: Disclosed is a fire-rated protector box that is engageable in a flush box so that it imparts heat stabilizing properties to the flush box.
Patent NZ-505297-A (NZ)
Title: Type 2 helper t cell-selective immune response inhibitors
Inventor: ISOBE YOSHIAKI
IPC: C07D473/00
Filed: 1998-12-21
Abstract: A type 2 helper T cell-selective immune response inhibitor of formula (I), the tautomer or a salt of the purine derivative, wherein; R2 is hydrogen or a C1-14 hydrocarbon group in which -CH2- not directly bound to the purine skeleton and CH2 in -CH3 not directly bound to the purine skeleton may be substituted by carbonyl, sulfonyl, -O- or -S-; =CH2 may be substituted by =O or =S; C-H in -CH2- not directly bound to the purine skeleton, C-H in -CH3- not directly bound to the purine skeleton, C-H in >CH- not directly bound to the purine skeleton, C-H in =CH- not directly bound to the purine skeleton and C-H in =CH2 may be substituted by N, C-halogen or C-CN; R6 is hydroxyl, amino or amino which is mono- or di-substituted by a C1-10 hydrocarbon group(s); R8 is hydroxyl, mercapto, C1-18 acyloxy or C1-19 hydrocarbon group-substituting oxycarbonyloxy; and R9 is a C1-14 hydrocarbon group in which -CH2- not directly bound to the purine skeleton and CH2 in -CH3 not directly bound to the purine skeleton may be substituted by carbonyl, sulfonyl, -O- or -S-, =CH2 may be substituted by =O or =S; C-H in -CH2- not directly bound to the purine skeleton, C-H in -CH3- not directly bound to the purine skeleton, C-H in >CH- not directly bound to the purine skeleton, C-H in =CH- not directly bound to the purine skeleton and C-H in =CH2  and C-H in CH may be substituted by N, C-halogen or C-CN. The type 2 helper T cell selective immune response inhibitor enhances the immune response on the type 1 helper T cell side and simultaneously inhibits the immune response on the type 2 helper T cell side.  The purine derivatives are used as the active ingredient of pharmaceutical compositions in the treatment of allergic or autoimmune diseases.
Patent NZ-507350-A (NZ)
Title: Semi-synthetic ecteinascidins and use in treatment of tumors
Inventor: RINEHART KENNETH L
IPC: A61K35/56
Filed: 1999-04-05
Abstract: Numerous  semi-synthetic ecteinascidin  (Et)  species, designated  herein  as Et 757, Boc-Et 729,  Iso-Et  743,  Et 875,  and Et 1560 are disclosed. The physical properties  of these  compounds,  their preparation and  bioactivities  are also disclosed.
Patent NZ-513167-A (NZ)
Title: Closed extruded closure
Inventor: LAGLER LOUIS
IPC: B65D50/04
Filed: 1999-10-30
Abstract: A closed extruded plastic closure (20) having a first part (21) and a second part (22). The first part (21) is connected to the second part (22) by means of a snap-on hinged connection. The parts (21, 22) have no main hinged connection with each other and are connected to one another instead by means of two elements (23.1, 23.2) and two hinged connections (24.1, 24.2, 25.1, 25.2) bordering on non-adjacent sides of said elements (23.1, 23.2). Elements (39) are also included which serve as original warranty seal due to the fact that it indicates whether the closure has been opened before. If required, an active element (57) and a counter element (58) serve as locking mechanism and prevent unintentional opening of the closure (20).
Patent NZ-513174-A (NZ)
Title: Thrombin inhibitors useful as anticoagulants
Inventor: LEE KOO
IPC: C07D/
Filed: 1999-12-29
Abstract: Peptide derivatives of formula (I), having high anti- thrombotic activity and high oral bioavailability that are useful as anticoagulants wherein: n is 1, 2 or 3; A is hydrogen, alkyl, cycloalkyl, aryl, -SO- 2R1, -SO3R1, -COR1, -CO2R2, -PO(OR1)2, -(CH2)mCO2R1, - (CH2)mSO2R1, -(CH2)mSO3R1, -(CH2)mPO(OR1)2, -PO(R1)2; B is hydrogen or alkyl; C and D are identical and selected from the group consisting of phenyl unsubstituted or substituted with one or two substituents selected from the group of alkyl, alkoxy, CF3, methylenedioxy, halogen, hydroxy, -NR3R4, cycloalkyl or a 5-6 membered heterocyclic ring which may be saturated or unsaturated, wherein the 1-3 heteroatoms are selected from N, O and S; E is a 5 membered ring system with two double bonds; and F is -C(NH)N(R7)2, - C(NH2)NN(R7)2, -C(NH2)NOH, or -CH2NH(R7). Also disclosed is a method for producing said peptide derivatives and their use in preparing medicaments for modulating trypsin like serine proteases, thrombin and for inhibiting thrombin.
Patent NZ-513549-A (NZ)
Title: Malaria vaccine
Inventor: CORRADIN GIAMPIETRO
IPC: A61K39/002
Filed: 2000-02-17
Abstract: A polypeptide having the amino acid sequence of the  C- terminal   part  of  the  circumsporozoite  protein   of   a Plasmodium species, said polypeptide further comprising  the four  terminal  cysteines from which at least  one  pair  is oxidized.    Also  disclosed is a vaccine  against  malaria, comprising said polypeptide.