baber/WOPTO huggingface dataset:
Patent BR-PI1003359-B1 (BR)
Title: Material varistor para um descarregador de surtos, processo para a preparação de um material varistor e uso do material varistor
Inventor: FELIX GREUTER
IPC: H01C7/112
Filed: 2010-09-30
Abstract: material varistor de alta intensidade do campo. a presente invenção refere-se a um material varistor para um descarregador de surtos com intensidade do campo de comutação alvo variando de 250 a 400 v/mm compreendendo zno que forma uma fase de zno e bi expresso como bi~ 2~o~ 3~ que forma uma fase de oxido de bismuto intergranular, dito material varistor ainda compreendendo uma fase de espinélio, caracterizado pelo fato de que a quantidade de uma fase de pirocloro compreendida no material varistor é tal que a relação da fase de pirocloro para a fase de espinélio é menor do que 0,15:1.
Patent BR-PI1014920-B1 (BR)
Title: luva ambidestra, e luva reversível
Inventor: JAMES L HULL
IPC: A41D19/00
Filed: 2010-04-06
Abstract: luva ambidestra, e luva reversível uma luva (10) ambidestra que inclui uma região de polegar (16), uma região de dedo indicador (24), uma região de dedo médio (26), uma região de dedo anelar (28) e região de dedo mínimo (30), todas alinhadas ao longo de um eixo comum. a região de dedo indicador (24) é rotacionada através de noventa graus em relação às orientações de todas das regiões de dedo médio, anelar e mínimo (26, 28, 30) para prover inserção mais fácil de uma mão na luva (10). um padrão texturizado (34) é provido nas superfícies da luva (10) usada para prender objetos. o padrão (34) é um dentre um formato de leque em relevo e formato de losango em relevo.
Patent BR-PI1101389-B1 (BR)
Title: Conjunto de cubo
Inventor: CONOR CROWLEY
IPC: B60B27/00
Filed: 2011-03-29
Abstract: conjunto de cubo. é apresentado um novo conjunto de cubo pré-montado tendo todos os componentes padrão (incluindo os mancais interno e externo, espaçador, e vedação de lubrificante) pré-montados dentro do cubo na instalação de fabricação. além disto, a instalação de fabricação também fixa um conjunto de porca de fuso pré-posicionado ao conjunto de cubo. neste modo de realização, o conjunto de cubo pré-montado (com o conjunto de porca de fuso pré-posicionado fixado ao cubo) não tem partes separadas ou soltas, facilitando a expedição e instalação do conjunto de cubo. a instalação requer apenas a colocação do novo conjunto de cubo sobre o fuso e o aperto da porca de retenção pré-posicionada, instalada de fábrica.
Patent EA-001617-B1 (EA)
Title: Excitatory amino acid derivatives
Inventor: MASSEY STEVEN M
IPC: C07D307/93
Filed: 1996-11-12
Abstract: 1. A compound of the formula   in which X represents O, S, SO or SO2; substituent R represents a hydrogen atom; a phenyl C1-4-alkyl group; or diphenyl C1-4-alkyl group; which is unsubstituted or substituted on phenyl ring by one or two substituents selected independently from halogen, C1-4-alkyl, C1-4-alkoxyl and phenyl or non-toxic metabolically labile esters or amides thereof; or pharmaceutically acceptable salts thereof. 2. A compound as claimed in Claim 1, in which substituent X represents O or S. 3. A compound as claimed in any one of Claims 1 to 2, which has the stereochemistry shown below.   4. A compound as claimed in any one of Claims 1 to 3, in which substituent R represents hydrogen. 5. A compound as claimed in Claim 1, which is selected from 1SR, 4SR, 5RS, 6SR-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid; 1SR, 4SR, 5RS, 6SR-4-amino-2-thiabicyclo-[3.1.0]hexane-4,6-dicarboxylic acid, 1SR, 4RS, 5RS-4-amino-(2-sulfonylbicyclo[3.1.0]hexane)-4,6-dicarboxylic acid, and 1SR, 3RS, 4SR, 5RS, 6SR-3-(3-chloro-4-fluorobenzyl)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid and 1SR, 4SR, 5RS, 6SR-4-amino-2-thiabicyclo-[3.1.0]hexane-4,6-dicarboxylic acid. 6. A compound as claimed in Claim 1, which is 1R, 4R, 5S, 6R-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid. 7. A process for the preparation of a compound of formula I which comprises (a) hydrolyzing a compound of formula   in which substituent R<1> represents a hydrogen atom or an acyl group and substituent R<2> represents a carboxyl group or an esterified carboxyl group, or a salt thereof; (b) hydrolyzing a compound of formula   in which substituent R<3> represents a carboxyl group or an esterified carboxyl group, and R<4> and R<5> each independently represent a hydrogen atom, a (C2-6)-alkanoyl group, a C1-4-alkyl group, a C3-4-alkenyl group or a phenyl-C1-4-alkyl group in which the phenyl is unsubstituted or substituted by halogen atom, C1-4-alkyl or C1-4-alkoxy group, or a salt thereof; or (c) deprotecting a compound of formula   in which R<6> represents a hydrogen atom or a nitrogen atom protecting group and each of R<7> and R<8> independently represent a hydrogen atom or a carboxyl protecting group, or a salt thereof; whereafter, if necessary and/or desired (i) resolving the compound of formula I; (ii) converting the compound of formula I into a non-toxic metabolically labile ester (or amide) thereof; and/or; (iii) converting the compound of formula I or a non-toxic metabolically labile ester or amide thereof into a pharmaceutically acceptable salt thereof. 8. A pharmaceutical formulation, which comprises a compound as claimed in Claim 1 and a pharmaceutically acceptable carrier, diluent or excipient.
Patent EA-002166-B1 (EA)
Title: Pharmaceutical combinations containing tramadol - a medicament for ttreating migraine
Inventor: MOMBERGER HELMUT
IPC: A61K31/415
Filed: 1999-02-17
Abstract: 1. Use of a pharmaceutical composition comprising at least one an antiemetic compound of prokinetic action or pharmaceutically acceptable salts thereof and tramadol, its enantiomers or pharmaceutically acceptable salts as a medicament for treating migraine or migraine-like headaches. 2. The use of claim 1, wherein metoclopramide, domperidone or 5HT3 antagonists are used as antiemetic compound. 3. The use of claim 1, wherein the pharmaceutical composition contains 5-80 mg of the antiemetic compound or salts thereof and 50-400 mg of tramadol or salts thereof. 4. The use of claim 1, wherein the pharmaceutical composition is administered preferably perorally.
Patent EA-003433-B1 (EA)
Title: Transmittance meter
Inventor: ZHUKOV OLEG NIKOLAEVICH
IPC: G01W1/00
Filed: 2002-02-18
Abstract: The transmittance meter, including an emitter, a near base receiver and a far base receiver, which are optically coupled with the emitter, at that the emitter includes a light source, a first lens and a beam splitting means, which are optically coupled with the light source power supply, output of which is connected with the light source input, a first protector, optically coupled with the beam splitting means, a first photocurrent amplifier input of which is connected with the first photodetector output, a computer, the first output of which is connected with the computer's first input, a voltage-reference source, output of which is connected with the first input of the AD converter; the near base receiver includes a second photodetector, a second lens, optically coupled with the second photodetector, a second photocurrent amplifier input of which is connected with the output of the second photodetector, the far base receiver includes a third photodetector, a third lens, optically coupled with the third photodetector, a third photocurrent amplifier, input of which is connected with the output of the third photodetector, characterized in that a clock-pulse generator is incorporated into the emitter, the output of this generator is connected with the second input of the first AD converter, the third input of the first AD converter is connected with second output of the computer, the fourth input of the first AD converter is connected with the-first photocurrent amplifier output, a second AD converter, output of which is connected with the computer's second input, the first input of the second AD converter is connected with the output of the voltage reference source, the second input of the second AD converter is connected with the output of the clock-pulse generator, the third input of the second AD converter is connected with the computer's second output and the fourth input of the second AD converter is connected with the output of the second photocurrent amplifier, a third AD converter, output of which is connected with the computer's third input, the first input of the third AD converter is connected with the output of the voltage-reference source, the second input of the third AD converter is connected with the output of the clock-pulse generator, the third input of the third AD converter is connected with the computer's second output, the fourth input of the third AD converter is connected with the output of the third photocurrent amplifier.
Patent EA-010258-B1 (EA)
Title: Drug discovery method
Inventor: OFER DROR
IPC: G16B45/00
Filed: 2002-07-24
Abstract: A method of obtaining information about a chemically active area of a target molecule, for example for drug discovery, comprising: providing a set of substantially rigid chemical gauges; reacting said target with a plurality of gauges of said set of gauges; assaying a binding of said gauges with said target to obtain a plurality of assay results; and analyzing said assay results to obtain information about said chemically active area.
Patent EA-007997-B1 (EA)
Title: Stepless transmission (variants)
Inventor: GASIMOV NASIB MOBIL OGLY
IPC: F16H37/08
Filed: 2004-11-26
Abstract: The invention relates to transport mechanical engineering and can be used in the form of a mechanism for the speed variation of power delivery in the transport means. The inventive stepless transmission comprises drive, intermediate and output shafts which are axially arranged with respect to each other, a two double-link planetary differential whose links are disposed at an angle of 180 DEG to each other and whose sun gear is embodied in the form of a drum provided with two rows of internal toothed paths which are constantly meshed with the first and second pinion sets. The first pinion set is connected to the drive shaft by means of a carrier, the second set is connected to the driven shaft, wherein said two shafts are interconnected by means of gears with the intermediate shaft. Said invention also relates to the stepless transmission variants, wherein brake means can be mounted in the drum area on the drive and driven shaft-carriers and/or the dampers and/or breaking devices can be mounted on the drive and driven shafts-carriers in the area of the pinion sets. The inventive two-link planetary differentials can be combined in a successive or in a parallel manner.
Patent EA-010430-B1 (EA)
Title: Combination of an nmda receptor antagonists and a selective serotonin reuptake inhibitor for the treatment of depression and other mood disorders
Inventor: GUPTA SANDEEP
IPC: A61K31/13
Filed: 2004-05-27
Abstract: The present invention provides a method for the treatment of depression, including treatment-resistant depression, and other mood disorders using a combination of an NMDA receptor antagonist and a SSRI that is citalopram or escitalopram. It has unexpectedly been shown that the combination has a synergistic and potentiated effect of either compound as monotherapy, resulting in an enhanced therapeutic effect at lower doses.
Patent EA-010286-B1 (EA)
Title: Delta d crystalline form of ivabradine hydrochloride, process of preparation thereof and pharmaceutical compositions containing the same
Inventor: HORVATH STEPHANE
IPC: A61P9/00
Filed: 2006-10-10
Abstract: Delta d crystalline form of ivabradin hydrochloride of formula (I),characterized by a X-ray powder diffraction profile.Medicaments.
Patent EA-011884-B1 (EA)
Title: Varicella zoster virus vaccine
Inventor: HANON EMMANUEL JULES
IPC: A61P31/22
Filed: 2006-03-01
Abstract: Use of an immunogenic composition comprising VZV gE, or immunogenic fragment thereof, and a TH-1 adjuvant in the preparation of a medicament for the prevention or amelioration of shingles and/or post herpetic neuralgia. Compositions comprising a truncated VZV gE antigen and an adjuvant containing QS21, cholesterol and 3D MPL are also claimed.
Patent EA-017436-B1 (EA)
Title: Novel formulations which stabilize and inhibit precipitation of immunogenic compositions
Inventor: KHANDKE LAKSHMI
IPC: A61K47/12
Filed: 2007-04-19
Abstract: The present invention addresses an ongoing need in the art to improve the stability of immunogenic compositions such as polysaccharide-protein conjugates and protein immunogens. The invention broadly relates to novel formulations which stabilize and inhibit precipitation of immunogenic compositions. More particularly, the invention described hereinafter, addresses a need in the art for formulations which stabilize and inhibit particulate formation (e.g., aggregation, precipitation) of immunogenic compositions which are processed, developed, formulated, manufactured and/or stored in container means such as fermentors, bioreactors, vials, flasks, bags, syringes, rubber stoppers, tubings and the like.
Patent EA-019923-B1 (EA)
Title: Compositions with reduced dimer formation
Inventor: HAFNER RODERICK PETER
IPC: A61K9/19
Filed: 2009-11-27
Abstract: The present invention relates to the use of a non-reducing carbohydrate or carbohydrate derivative and at least one agent which inhibits dimer formation in a freeze-dried composition comprising at least one peptide that contains a free cysteine residue, to provide a freeze-dried composition with improved long-term storage stability.
Patent EA-027456-B1 (EA)
Title: Process for obtaining thermal energy by the combustion of hydrogen in admixture with carbon oxides, nitrogen oxides and/or sulphur oxides and installation for the application of the process
Inventor: ROIBU CONSTANTIN
IPC: F23C99/00
Filed: 2012-08-22
Abstract: The invention relates to a process and an installation for obtaining thermal energy by the combustion of hydrogen in admixture with carbon oxides, nitrogen oxides and/or sulphur oxides in the presence of a magnesium catalyst which is a mixture of magnesium chips and powder. The process for obtaining the thermal energy according to the invention consists of a first stage wherein the combustion of hydrogen in admixture with carbon oxides, nitrogen oxides and/or sulphur oxides in the presence of the magnesium catalyst is performed in an enclosure with orifices for discharging the gases and the carbon and/or sulphur atoms, with the formation of MgO and water and a second stage wherein magnesium is regenerated in the same enclosure by introducing extra hydrogen. The installation for the application of the process comprises a housing (1) made of stainless steel whereupon a cover (3) is secured, said cover (3) being connected to a conduit for supplying hydrogen (2), said housing (1) comprising a chamber for the uniform distribution of hydrogen (M1), a chamber for the uniform distribution of the mixture comprising carbon oxides, nitrogen oxides and/or sulphur oxides (M2), a chamber (M3) for the homogenization of hydrogen in admixture with carbon oxides, nitrogen oxides and/or sulphur oxides, a catalyst chamber (14) wherein a magnesium catalyst is placed as a mixture of chips and powder, copper or stainless steel pipes (7), (8), which ensure the transport and uniform distribution of hydrogen and a gaseous mixture of carbon oxides, nitrogen oxides and/or sulphur oxides, respectively, a deflector (16) for the homogenization of the gaseous mixture, and at the outer side of the housing there are provided a conduit for the completion of the catalyst (17), a conduit for supplying hydrogen (2), a conduit for supplying the gaseous mixture comprising carbon oxides, nitrogen oxides and/or sulphur oxides (4), and a conduit for discharging carbon and/or sulphur (10).
Patent EA-029414-B1 (EA)
Title: Video frame encoding apparatus and video frame decoding apparatus
Inventor: AMAMOTO TOMOYUKI
IPC: H04N19/61
Filed: 2010-03-17
Abstract: The amount of metadata is decreased while maintaining a high degree of freedom in choosing segment formats and transformation formats adapted to local properties of video frames. A video frame encoding apparatus (10) divides input video frames into blocks of a prescribed format and encodes the video frames block by block. The video frame encoding apparatus comprises: a prediction parameter determining portion for determining the segmental structure of the block; a predicted image producing portion that generates a predicted image for each segment defined by the segmental structure; a transformation coefficient producing portion which applies any of the transformations included in a predetermined transformations set to the prediction residual that is a difference between the predicted image and the input video frames; a possible transformations deriving portion for determining the list of possible transformations that comprises a list of applicable transformations based on information on the segment form, the information on the segment form characterizing each segment in respect of the segment size, specific features of the segment format or its level in the segmental structure; a frequency transformation determining portion to determine, for each of the blocks, a transformation selection flag that designates the transformation to be applied to the prediction residual in the block among a plurality of transformations included in the possible transformations list; and a variable-length-encoding portion which, on the basis of the possible transformations list, performs variable-length encoding on the transformation selection flag, wherein the predetermined set of transformations includes a first transformation and a second transformation having similar quantitative ratios of the longitudinal and transverse lengths of the transformation format in respect of the first transformation, and having a smaller transformation format than the first transformation, and the possible transformations deriving portion includes the first transformation and excludes the second transformation from the possible transformations list if the segment belongs to a preset level that is not the lowest level, and includes the second transformation in the possible transformations list if the segment belongs to a level lower than the preset level that is not the lowest level.
Patent EA-039598-B1 (EA)
Title: Compound targeting il-23a and tnf-alpha and uses thereof
Inventor: BARRETT RACHEL REBECCA
Filed: 2015-09-03
Abstract: The invention relates to compounds specific for IL23A and TNF-alpha, compositions comprising the compounds, and methods of use thereof. Nucleic acids, cells, and methods of production related to the compounds and compositions are also disclosed.
Patent EA-034864-B1 (EA)
Title: Method of treating moderate to severe eosinophilic asthma
Inventor: BRUSSELLE GUY
IPC: C07K16/24
Filed: 2015-08-28
Abstract: The present invention provides a method of treating moderate to severe eosinophilic asthma in a patient comprising administering to the patient intravenously or subcutaneously from about 0.3 to 3 mg/kg of reslizumab, wherein 12 months prior to the administering, the patient had at least one asthma exacerbation requiring oral, intramuscular or intravenous prescription of a corticosteroid, but prior to the administering, asthma symptoms in the patient are inadequately controlled with a current asthma therapeutic and the blood eosinophil levels are equal to or greater than 400/l.
Patent EA-034714-B1 (EA)
Title: High polymer content hybrid drag reducers
Inventor: MILLIGAN STUART N
IPC: C08L23/00
Filed: 2008-07-30
Abstract: A drag reducing composition comprising particles of at least two different drag reducing polymers. The different drag reducing polymers can be formed by different processes, such as bulk polymerization or emulsion polymerization, and the particles of the different drag reducing polymers can have different mean particle sizes. The drag reducing compositions can be added to a hydrocarbon-containing fluid to decrease the pressure drop associated with the turbulent flow of the hydrocarbon-containing fluid through a conduit.
Patent ES-2176077-B1 (ES)
Title: Motor por variacion del volumen de un fluido.
Inventor: GOMEZ HERNANDEZ ALFREDO JOSE
IPC: F03B17/00
Filed: 2000-04-19
Granted: 2004-06-01
Abstract: Se trata de un motor por variación del volumen de un fluido, formado a partir de pares de cilindros, abiertos en su parte superior y unidos en la inferior, donde se forma un cárter, con su correspondiente cigüeñal, bielas y pistones. Sobre esos pistones se disponen sendos orificios de expulsión y, por encima de ellos, sendas compuertas que se cerrarán o abrirán alternativamente. Los cilindros están llenos de un fluido, y es el peso del mismo el que ejerce presión sobre el pistón que está en punto muerto superior y con su compuerta abierta. La cámara del cilindro contrario, formada por el pistón en el punto muerto inferior y su correspondiente compuerta cerrada, se evacuará de fluido a través del orificio de expulsión, volviendo al cilindro por su parte superior. Ese proceso de presión y expulsión será alternativo en uno y otro cilindros, produciendo el movimiento continuado del motor.
Patent ES-2176082-B1 (ES)
Title: Bacterias con la capacidad de unir metales pesados y su empleo en la detoxificacion de medios contaminados con metales pesados.
Inventor: DE LORENZO PRIETO VICTOR
IPC: C12N1/21
Filed: 2000-05-31
Granted: 2004-01-01
Abstract: Bacterias con la capacidad de unir metales pesados y su empleo en la detoxificación de medios contaminados con metales pesados. La bacteria con capacidad de unir metales pesados es una bacteria adaptada al suelo y resistente a metales pesados, bien de forma natural o mediante manipulación genética, y ha sido modificada para expresar en su superficie, al menos, una proteína o una secuencia peptídica con la capacidad de unir uno o más metales pesados. En una realización particular, la bacteria adaptada al suelo y resistente, de forma natural, a metales pesados es Ralstonia eutropha, y la proteína capaz de unir uno o más metales pesados es una metalotioneína de un medio, sólido o líquido, contaminado con metales pesados.
Patent ES-2216672-B1 (ES)
Title: Sistema para limpieza mecanica del interior de barricas, toneles o cubas en general.
Inventor: PAYUETA RUBIO GUILLERMO
IPC: B08B9/087
Filed: 2002-03-07
Granted: 2005-12-16
Abstract: Sistema para limpieza mecánica del interior de barricas, toneles o cubas en general, que se basa en un cepillado/fresado interior de la barrica sin desmontar, realizándose dicho cepillado/fresado en el sentido longitudinal de sus duelas, con arranque de material en un sentido de avance y recorrido en vacío en un sentido de retorno, o viceversa. De aplicación para limpieza del interior de barricas sin desmontarlas.
Patent ES-2197022-B1 (ES)
Title: Procedimiento no invasivo de deteccion y analisis de microorganismos en productos lacteos en envases laminados de papel o carton utilizando ondas elasticas por acoplamiento en seco.
Inventor: ELVIRA SEGURA LUIS
IPC: C12Q1/04
Filed: 2002-06-14
Granted: 2005-03-01
Abstract: Procedimiento no invasivo de detección y análisis de microorganismos en productos lácteos en envases laminados de papel o cartón utilizando ondas elásticas por acoplamiento en seco. El objeto es la detección del crecimiento de microorganismos dentro de recipientes cerrados de productos lácteos midiendo el cambio de los parámetros de propagación de ondas ultrasónicas que se propagan en su interior debido a las modificaciones que sufren los productos lácteos cuando crecen distintos microorganismos. La técnica consiste en introducir un pulso ultrasónico a través de la pared del recipiente, captándolo con un sensor tras atravesar dicho recipiente. La medida de los parámetros tales como el retardo, la amplitud de la señal y la distorsión armónica, delatan los cambios fisicoquímicos producidos por contaminación microbiana. Los procedimientos usados en la industria láctea son los habituales en microbiología clínica, por lo que son invasivos y muy costosos de mantenimiento y el análisis es más económico.