baber/WOPTO huggingface dataset:
Patent AP-2003002762-A0 (AP)
Title: Pyrazole compounds useful as protein kinase inhibitors
Inventor: DAVIES ROBERT
IPC: A61P19/02
Filed: 2001-09-14
Abstract: This invention describes novel pyrazole compounds of formula TI:wherein Ring C is selected from a phenyl, pyridinyl, pyrimidinyl, pyridazinyl, pyrazinyl, or L, 2, 4-triazinyl ring, and R2, R2, Rs, and Ry are as described in the specification. Ring C has an ortho substituent and is optionally substituted in the non-ortho positions. R2 and R2 are optionally taken together with their intervening atoms to form a fused ring system, such as an indazolc ring: and R1 and R* are optionally taken together with their intervening atoms to form a fused ring system, such as a quinazoline ring. The compounds are useful as protein kinase inhibitors, especially as inhibitors of GSK-3, for treating diseases such as diabetes and Alzheimer's disease.
Patent ZW-8384-A1 (ZW)
Title: A process for the manufacture of nitric acid esters
Inventor: ANTHONY JOHN STIFF
IPC: C07C201/02
Filed: 1984-06-11
Abstract: The invention concerns a process for the preparation of nitric acid esters of organic hydroxy compounds by reacting an organic hydroxy compound with nitric acid in the presence of sulphuric acid and in a solvent, followed by separating off the spent acid, substantially neutralizing the residual acidity of the organic solution, and removing solvent to leave the organic nitrate. From 95% to 220% of the stoichiometric requirement of nitric acid for complete nitration is used. The mole ratio of water to sulphuric acid at the end of the reaction is from 0,2:1 to 2,5:1. From 200 to 2000 ml of solvent per mole of hydroxy group is present. Yields of at least 92% are obtained. The invention is particularly suitable for the preparation of alkyl nitrates, alkylene or polyalkylene glycol, monoalkyl ether mononitrates, alkylene or polyalkylene glycol dinitrates, diol nitrates, nitrates containing homocyclic or heterocyclic rings, or nitrates derived from polyols.
Patent IE-910197-A1 (IE)
Title: Recombinant poxvirus internal cores
Inventor: PAOLETTI ENZO
IPC: A61K39/295
Filed: 1991-01-21
Abstract: What is described is a modified recombinant poxvirus, such as vaccinia virus, fowlpox virus and canarypox virus, having an internal core containing DNA from a non-pox source in a nonessential region of the poxvirus genome. The recombinant poxvirus is modified by disassociating the internal core from outer membranes of the poxvirus. The DNA codes for and expresses a gene product in a cell cultured in vitro and in a host in vivo without productive replication of the virus in the cell or in the host. What is also described is a vaccine containing the modified recombinant poxvirus for inducing an immunological response in a host inoculated with the vaccine.
Patent IE-910364-A1 (IE)
Title: Casting composition for producing ceramic green tapes, and¹the use thereof
IPC: C08K3/00
Filed: 1991-02-01
Abstract: A slip for the production of green ceramic sheets contains a volatile organic solvent, polyvinyl butyral, plasticisers, dispersants and a ceramic powder such as, for example, Al2O3. The polyvinyl butyral used contains at most 18 % by weight of vinyl alcohol units and preferably has a mean molecular weight of between 40,000 and 120,000. A constant and small shrinkage results on sinter-firing.
Patent IE-910390-A1 (IE)
Title: The use of retinoids to minimize skin damage
Inventor: SHANNON RONALD J
IPC: A61K31/20
Filed: 1991-02-06
Abstract: Pretreating areas of the body susceptible to the formation of pressure sores or ischemic ulcers with retinoids reduces the likelihood of such sores or ulcers occurring. Similarly, skin stripping caused by the removal of adhesives can be reduced by pretreating with retinoids. The retinoids can be formulated into a cream, ointment, lotion or hydrogel formulation or can be incorporated into the adhesive layer of a bandage or dressing or located at the skin contacting adhesive surface and adjacent strata of a bandage or dressing.
Patent MA-22297-A1 (MA)
Inventor: S W MORRALL
IPC: C11D1/52
Filed: 1991-09-27
Abstract: An alkyl sulphate-based, controlled sudsing liquid or solid laundry detergent compsn. Useful for cleaning fabrics in automatic washing machines comprises: (a) at least 1 wt. % of polyhydroxy fatty acid amide cpd. of formula R2-C-(O)-N(R1)-Z (I) (c) pref. a suds suppressing amt. of a suds suppressor. In (I), R1 = H, 1-4 hydrocarbyl, 2-hydroxyethyl and/or 2-hydroxypropyl; R2 = 5-31C hydrocarbyl; Z = polyhydroxyhydrocarbyl having linear hydrocarbyl chain with at least 3-OH gps. directly connected to the chain or its alkoxylated deriv. The compsn. has a wt. ratio of (a):(b) of 1:10 to 10:1. Also claimed is a detersive particle comprising 5-90 % of cpd. (I) and 10-90% of an alkylsulphate surfactant and 1-30 wt. % of a solubilising agent. The compsn. pref. comprises at least 3% of cpd. (I) and at least 3% alkylsulphate in a wt. ratio of 6:1 to 1:6 (esp. 1.25:1 to 1:4). The compsn. further comprises 1-30% of an auxiliary surfactant component selected from alkyl benzene sulphonate surfactants, alkyl ester sulphonate surfactants, alkyl ethoxylate surfactants, alkyl polyglycoside surfactants, paraffin sulphonate surfactants and/or alkyl phenol alkoxylate surfactants. The suds suppressor is selected from silicone suds suppressors, hydrocarbon suds suppressors and/or monostearyl phosphate suds suppressors (esp. at least 0.5 wt. % of a monocarboxylate fatty acid or its salt).
Patent MA-28198-A1 (MA)
Title: Procede de realisation de carte geographique numerique par lissage des parcours positions
Inventor: ABDESSADEK EL OUNASSE
Filed: 2005-03-29
Abstract: PROCEDE DE REALISATION DE CARTE GEOGRAPHIQUE NUMERIQUE PAR LISSAGE DES PARCOURS POSITIONS Le procédé se base sur des parcours de milliers de positions (latitude , longitude) sans besoin d'image satellite. Le dispositif de récolte des données à été conçu et développé en interne, il consiste à intégrer un GPS de dernière génération à commande de microcontrôleur programmé pour prendre la position instantanée et la communiquer à un ordinateur intégré programmé pour récolter les données du GPS et les stocker dans des fichiers de mesures. Le tout est fixée sur un véhicule. Nous pouvons faire autant de parcours que possible sans difficulté particulière et sans besoin d'une supervision particulière Ces parcours sont réalisés sur toutes les artères de la zone étudiée. L'ensemble des fichiers de mesure est projeté sous logiciel GIS pour faire apparaître toutes les positions. Les profils de tous les reliefs artères de la zone se dessinent, nous appliquons alors un lissage pour reproduire en tracé les dis artères. Par approximation et étude terrain, nous pouvons produire tout les autres reliefs. Le résultat obtenu est corrigé sur le terrain. L'ensemble est enrichit par des données relatives à chaque relief. Le produit réalisé est vérifié sur le terrain, ensuite validé
Patent MA-37822-A1 (MA)
Inventor: SAID ZAHRAOUI
IPC: H01L21/3205
Filed: 2015-01-28
Abstract: صياغة كيميائيّة وعملية تسمح بترسب طبقة حاجزة مكونة أساسا من nib تستعمل يعزل طبقة سفليّة عازلة تضم مجموعة من التجويفات،بتطبيق عملية ذاتية التحفيز،إضافة إلى صياغة كيميائيّة،تسمح بترسب طبقة إنبات نحاسيّة على حاجز الانتشار، ثم ملأ التجويفات،بفضل عملية إلكتروليتيّة.
Patent MA-39156-A1 (MA)
Title: Sels cristallins solubles dans l'eau de certaines harringtonines protonées sans ambigüité sur leur azote alcaloïde et leur utilisation en tant que médicaments chimiothérapeutiques
Inventor: ROBIN JEAN-PIERRE
IPC: C07D491/14
Filed: 2014-12-30
Abstract: L'invention concerne des sels d'harringtonine à l'état solide présentant un azote protoné détecté dans une analyse d'état solide et représentés par la formule (1) comprenant un solvate obtenu par réaction d'un ester de céphalotaxine représenté par la formule (2) dans laquelle r
Patent UY-25908-A1 (UY)
Title: Composiciones oftálmicas que contienen ciclosporina, un surfactante y un vehículo acuoso
Inventor: KAWASHIMA YOICHI
Filed: 2000-01-17
Abstract: Composición oftálmica, que comprende una ciclosporina (particularmente ciclosporina A), un surfactante seleccionado de ésteres de ácidos grasos polioxietilenos, ésteres alquilfenilos polioxietilenos y ésteres alquilos polioxietilenos, o mezclas de los mismos, y un vehículo acuoso, estando la ciclosporina en solución; dicha composición además comprende un agente espesador, seleccionado en de celulosa, polímeros carboxivinilos, polímeros polivinilos y polivinilpirrolidonas.. En especial son preferidas formulaciones en forma de gotas (con base acuosa) para ojos que comprenden una ciclosporina como ingrediente activo y que son adecuadas para el tratamiento de enfermedades del ojo o de órganos o tejidos que lo rodean (como por ejemplo la cornea o el epitelio corneal), asociados en un sujeto que tiene necesidad de ella. Si se desea, puede haber otros excipientes presentes, por ejemplo, un agente isotónico, un tampón, un agente de conservación y/o un agente de control de pH, o agua esteril purificada.
Patent UY-28083-A1 (UY)
Inventor: SUAREZ NICOLAS FERNANDEZ TOURN
IPC: A61H1/00
Filed: 2003-11-14
Abstract: The current Invention Patent Application is related to the applications of computer technology (hardware and software) to the field of medicine, in particular it refers to a Vestibular Rehabilitation Unit that is for the treatment of balance disorders in an individual of distinct origin. It does not refer to a treatment method but rather to equipment to carry out such treatments Additionally, the equipment can be used to develop psychomotor skills.
Patent UY-28258-A1 (UY)
Title: Tratamiento terapeutico
Inventor: ABRAHAMSSOM HASSE ROALAND
IPC: A61P1/10
Filed: 2004-04-05
Abstract: Se describe el uso de un inhibidor del IBAT en el tratamiento y/o profilaxix de la constipación en un animal de sangre caliente, como el hombre.
Patent UY-29785-A1 (UY)
Title: Cultivar de arroz denominados `cl131´
Inventor: LINSCOMBE STEVEN D
IPC: A01H5/10
Filed: 2006-09-08
Abstract: Se describe un cultivar de arroz novedoso, denominado "CL131". La invención se refiere a las semillas del cultivar de arroz ´CL131´, a las plantas de arroz "CL131", y a los métodos para producir la planta de arroz producida cruzando el cultivar "CL131" con el mismo u otra variedad de arroz, y a conversiones de gen simple de tales plantas. La invención se refiere además a las semillas de arroz hidrido y plantas producidas cruzando el cultivar "CL131" con otro cultivar de arroz. La invención se refiere además a otros derivados del cultivar "CL131".
Patent UY-31573-A1 (UY)
Title: Haplotipos especificos de raza para fenotipos polled (sin cuernos) en ganado
Inventor: VOSS NATHAN
IPC: C12N15/10
Filed: 2008-12-22
Abstract: La presente invencion se relaciona con la identificacion de polimorfismos de nucleotido unico (SNP) específicos de la raza y sus haplotipos, en el genoma bovino, en o cerca de gen(es) que codifican polipéptidos asociados con el fenotipo Polled en la produccion de carne. La invencion abarca además métodos y sistemas, incluyendo procesos basados en redes, para administrar los datos de los SNP, los datos de los haplotipos y otros datos relativos a animales y manadas de animales específicos, asistencia veterinaria, datos de control de calidad y diagnostico, y administracion de ganado.
Patent ES-184147-A1 (ES)
Title: MEJORAS EN LA CONSTRUCCIoN DE ACCESORIOS MÉDICOS
IPC: A61M1/08
Filed: 1948-06-16
Abstract: Mejoras en la construcción de accesorios médicos constituidos particularmente por un recipiente con la forma sensiblemente de campana, cuyos bordes se destinan a aplicarse sobre una parte del cuerpo que se ha de tratar, caracterizadas porque se preve al menos una abertura de admisión de fluido y obturador de esta abertura.
Patent ES-187537-A1 (ES)
Title: Un condensador para vapor de cinc
IPC: C22B19/18
Filed: 1949-03-22
Abstract: Un condensador para vapores de zinc que comprende un recipiente cerrado que tiene una entrada para vapor de zinc y una salida para gas y destinado a retener una masa de zinc fundido en su fondo un árbol giratorio que se extiende oblícuamente a través de una pared del recipiente y dentro del interior del mismo en rotor montado sobre dicho árbol dentro del recipiente y destinado al ser girado a sumergirse dentro de la masa de zinc fundido y proyectar una lluvia de zinc fundido hacia arriba dentro del interior del recipiente y medios para hacer girar dicho árbol.
Patent ES-190538-A1 (ES)
Title: UNA DISPOSICIoN DE QUEMADOR DE COMBUSTIBLES LiQUIDOS
Filed: 1949-11-14
Abstract: Una disposición de quemador de combustibles líquidos constituida por un depósito que presenta un conducto central vertical configurado por un tubo que teniendo su extremo superior concéntrico con el cuello de dicho depósito atraviesa por el otro la base de éste sobresaliendo en magnitud apropiada por cual apéndice soporta a un anillo o disco con facultad de poder éste girar maniobrando por un mango dándose las circunstancias siguientes: a) de que rodeando al tubo central referido en el interior del depósito va situado el elevador de combustible formando por un manguito presentando en sus extremos superior e inferior respectivas pestañas que soportan a una o varias mechas de acción permanente no afectadas directamente por la combustión y sobre ésta a una corona circular de algodón u otra materia apropiada cuales mecha y corona quedan aprisionadas entre los extremos del tubo central y del cuello del depósito entre los que finalmente se adapta una corona metálica perforada que cubriendo a la de algodón referida tiene los espacios intermedios entre cada dos agujeros consecutivos de magnitud superficial ligeramente mayor que la que abarca cada agujero; y b) de que dentro del tubo central fijo juego otro tubo metálico cuyo extremo inferior se acopla de manera amovible con el anillo o disco giratorio antes mencionado apropósito para que al maniobrar el mango que mueve a aquel sea asimismo arrastrado el tubo interior limitándose mediante topes la magnitud angular de dicho giro entre límites convenientes; en el extremo superior del citado tubo giratorio van dispuestas tantas aletas radiales situadas en un mismo plano horizontal como agujeros presenta la corona metálica perforada que cubre a la de algodón viniendo situadas dichas aletas rozando o casi rozando con la referida corona metálica y teniendo cada una de ellas magnitud superficial ligeramente mayor que la de los agujeros de la corona metálica a la que se superponen; también en el extremo superior del tubo móvil va fijado el gasificador interno que girará con su soporte.
Patent ES-192778-A1 (ES)
Title: Un procedimiento para apilar hojas de capillo,de capa o de ambas clases,previamente formadas para hacer cigarros,cigarrillos o mazos de los mismos
Filed: 1950-05-01
Abstract: Un procedimiento de amontonar hojas de capillo capa o ambas formadas previamente para cigarros cigarrillos o mazos caracterizado porque las hojas se colocan en un depósito una sobre otra atravesadas en por lo menos dos direcciones predeterminadas de modo que las áreas de las hojas con las cuales están una sobre otra sean lo menores posible.
Patent ES-193919-A1 (ES)
Title: UN DISTRIBUIDOR DE FRAGMENTOS CALIBRADOS, GRANOS, SEMILLAS Y SEMILLAS CON CáSCARA
Filed: 1950-07-15
Abstract: Distribuidor de fragmentos calibrados granos semillas y semillas con cáscara caracterizado por el hecho de que dicho distribuidor está provisto por una parte de un recipiente cerrado de eje sensiblemente horizontal constituido por un cuerpo anular rotativo solidario de un eje de arrastre y por dos tabiques laterales obturadores de los cuales por lo menos uno es fijo y atravesado por el eje de arrastre y por un conducto de aducción de los fragmentos desembocando debajo del eje ; por otra parte de alveolos situados a intervalos apropiados dentro del cuerpo anular desembocando en una de sus caras y comunicando con el interior del recipiente mediante conductos o canales construidos para permitir solamente que entre en cada alveolo un solo fragmento y en fin medios asegurando la eyección del fragmento para una posición angular determinada del alveolo pero oponiéndose a su salida para las otras posiciones.
Patent ES-269684-A1 (ES)
Title: Apparatus for the treatment of a web of material by a fluid
IPC: D06B3/20
Filed: 1961-07-08
Abstract: A process for treating (e.g. washing, scouring, bleaching, mercerising, starching, breaking down, dyeing) textile material 1 (e.g. woven or spun flock) comprises passing the material through a duct 2, maintaining the material spaced from the walls and causing relative velocity between the material and the treatment fluid flowing through the duct, the cross-sectional area of the duct being so small and the relative velocity between the material and fluid being so high that the formation of a laminar boundary layer of fluid over a substantial part of the surface of the material is prevented. As shown the material passes upwardly through a zig-zag series of ducts while the fluid flows downwardly, the upper end of the ducts have a calibrated portion 5 whereby the pressure head of the fluid may be adjusted. Free or driven rollers 7 are provided at changes in direction of the duct. The path of the duct may be varied in accordance with the preceding and following processes. A wall may be spaced about the duct to carry a heating or cooling medium. Pressure pumps may be provided to cause the pressure differences in the treatment fluid.
Patent ES-280754-A1 (ES)
Title: Improvements in or relating to the preparation of penicillins
IPC: C07D499/48
Filed: 1962-09-13
Abstract: Penicillins of the general formula: <FORM:0962943/C1/1> wherein X represents an alkylene group may be prepared by reacting 6-aminopenicillamic acid with a mixed anhydride obtained from the appropriate a -phenyl-o -carbobenzoxy-aminoacid and an ester of chlorocarbonic acid, in the presence of a tertiary amine and splitting off the carbobenzoxy group by catalytic hydrogenation. Examples describe the production of (-)-b -amino-a -phenylethyl-, a -phenyl-g -aminopropyl- and a -phenyl-d -aminobutyl-penicillins. Specification 960,896 is referred to.
Patent ES-289025-A1 (ES)
Title: Improvements in or relating to flux coated low hydrogen welding electrodes
IPC: B23K35/365
Filed: 1963-06-14
Abstract: A method of preparing a moisture resistant coated low hydrogen welding electrode comprises applying to the surface of the electrode a moisture resistant basix flux and subsequently heat treating the coated electrode at a temperature within the range 520 DEG C. to 620 DEG C. wherein there is incorporated in the moisture resistant basic flux 10 to 25% by weight on the weight of the flux of an alkali metal silicate solution binder having an alkali metal silicate content of from 35% to 45% by weight on the weight of the solution and a molecular ratio of silica to alkali metal oxide in the alkali metl silicate within the range 2.9:1 to 3.9:1. The alkali metal silicate may be Na silicate and or K silicate. Fluxes are specified with their quantitative compositions which comprise limestone with various of the following: - fluorspar, rutile, Fe-Mn, Fe-Si, Fe-Ti, Fe-Mo, Fe-Cr, Fe-B, Fe-Nb, Si-Mn, Fe powder, Ni, Cr, zircon, felspar, clay and an organic pressing agent. Fluxes are specified which are suitable for electrodes to be used in welding of mild steel, low alloy high tensile creep resisting steel and austenitic steel.
Patent ES-292204-A1 (ES)
Title: Manufacture of magnesium phosphate by reaction of rock phosphate with magnesium sulfate
IPC: C05B9/00
Filed: 1963-10-04
Abstract: In a process for the manufacture of anhydrous magnesium phosphate, possibly in mixture with calcium sulphate, from rock phosphate, the rock phosphate is heated in a reaction mixture which contains magnesium sulphate and a salt which lowers the fusion temperature of magnesium sulphate, to a temperature at which the fusible ingredients of the reaction mixture are partially or fully fused while the phosphates remain solid, thereby to produce a partial fusion of the reaction mixture, and a product containing anhydrous magnesium phosphate is recovered from the reaction mixture. "Fusible ingredients" are those which fully liquefy and also those which merely sinter under the reaction conditions. The process may be carried out by melting or sintering of the salts other than orthophosphates present at any time, i.e. tertiary calcium orthophosphate at the beginning and increasing proportions of tertiary magnesium or mixed calcium-magnesium orthophosphates. The magnesium salt may be magnesium sulphate as such or another salt, e.g. the chloride together with an alkali metal sulphate or chloride as the fusion-temperature lowering component, or a naturally occurring double salt or salt mixture containing magnesium sulphate can be used. The rock phosphate and fusible ingredients may be fed, together or separately and continuously or in batches into a bath of molten salt from which magnesium phosphate and possibly calcium sulphate are withdrawn. Temperatures of 600 DEG C. to 300 DEG C. are suitable. Some CaSO4 may be removed from the product when the water-soluble ingredients of the reaction mixture are washed out. In Example (1) the reaction mixture comprises Florida phosphate (tertiary calcium phosphate, calcium fluoride and calcium carbonate) and astrakanite (MgSO4.Na2SO4). In other examples Morocco rock phosphate is heated with: (2) crude kieserite containing NaCl (3) kainite (5) mixed MgSO4.H2O, KCl and NaCl (6) mixed langbeinite and sodium sulphate. In Example (7) Florida phosphate and kieserite are added to a melt of CaSO4 and K2SO4 at the same rate as magnesium phosphate, K2SO4 and CaSO4 are withdrawn. The products can be used as mixed fertilizers.
Patent ES-294215-A1 (ES)
Title: Treating of plastic surfaces
IPC: H01B7/282
Filed: 1963-12-06
Abstract: In a method for treating a surface of organic plastics material to improve the bonding or adhesion properties thereof (e.g. ink receptivity), the plastics material is passed between a current-conductive material and at least two electrodes spaced and electrically insulated therefrom and maintained at high voltage direct current of opposite polarity, the surface of the material to be treated being exposed to and spaced from the electrodes with the reverse side of the material in intimate contact with the current-conductive material, whereby a direct current corona aura is developed and maintained from the electrodes to the moving surface of the plastics material being treated. The electrodes are on the same side of the current-conductive surface, so that the corona, which increases in intensity with the speed of surface being treated, does not pass through the plastics material but operates on only one surface thereof. In one embodiment (Fig. 1, not shown), a D.C. voltage, e.g. 17,000 volts, is applied to each of alternate electrodes 20, intermediate electrodes 21 being of opposite polarity. The electrodes are sharp-pointed sections of a hacksaw blade. A film 23 made of e.g. polyethylene polypropylene, polystyrene is passed via rolls 24, 26 over a conductive plate 22 which is in contact with the film, and insulated from the D.C. supply. In Fig. 2 (not shown), a corona is developed in the air gap between film 23, passing round insulated metal roll 221, and electrodes 201, 211 of opposite polarity. The electrodes are
Patent ES-306518-A1 (ES)
Title: Neomycin pamoate
IPC: C07H15/232
Filed: 1964-11-28
Abstract: Neomycin pamoate (i.e. embonate or 2,21-dihydroxy - 1,11 - dinaphthylmethane - 3,3 - dicarboxylate) is produced by reacting neomycin or an acid addition salt, e.g. sulphate with pamoic acid or a salt thereof, e.g. sodium salt. Water-soluble salts may be used in aqueous solution, the neomycin pamoate being precipitated. Neomycin pamoate is less toxic than the sulphate and is effective against intestinal infections. It is formulated into medicines (see Division A5).ALSO:Pharmaceutical compositions for the treatment of intestinal infections comprise neomycin pamoate (i.e. embonate or 2,21-dihydroxy-1, 11-dinaphthylamine-3, 31-dicarbonylate) and a carrier. The compositions may take the form of drops, suspensions, tablets, pills, capsules and cachets. Other drugs for the treatment of intestinal infections e.g. sulphonamides, gastro-intestinal absorbents and aluminium pamoate may be present.