baber/WOPTO huggingface dataset:
Patent CA-2367002-A1 (CA)
Title: Increasing cerebral bioavailability of drugs
Inventor: RON EYAL S
IPC: A61K9/20
Filed: 2000-03-20
Abstract: A method and compositions are provided for increased cerebral bioavailability of blood-born compositions by administering the composition of interest while increasing brain NO levels. This increase in NO levels may be accomplished by stimulating increased production of NO by eNOS, especially by adminstering L-arginine, by administering agents that increase NO levels independent of ecNOS, or by any combination of these methods. As NO is increased, cerebral blood flow is consequently increased, and drugs in the blood stream are carried along with the increased flow into brain tissue. By increased flow, the site of action will be exposed to more drug molecules. By stimulating increased NO production, administration of drugs that are not easily introduced to the brain may be facilitated and/or the serum concentration necessary to achieve desired physiologic effects may be reduced.
Patent CA-2367107-A1 (CA)
Title: Methods for limiting scar and adhesion formation
Inventor: DIZEREGA GERE
IPC: A61K38/08
Filed: 2000-03-22
Abstract: The present invention provides methods, kits, and pharmaceutical compositions for limiting scar or adhesion formation by administration of angiotensinogen, AI, AI analogues, and/or AI fragments and analogues thereof, AII analogues, AII fragments or analogues thereof, ACE inhibitors, AII AT2 type 2 receptor agonists, either alone or in combination with other compounds.
Patent CA-2367939-A1 (CA)
Inventor: RASALA APRIL PATRICIA
IPC: H04B10/27
Filed: 2002-01-16
Abstract: The present invention provides a wide-sense, non-blocking WDM cross-connect that utilizes a relatively small number of wavelength interchangers. The cross-connect of the present invention comprises first, second and third fabrics and one or more wavelength interchangers that interconnect the first and second fabrics.  Demands that require a change in wavelength are routed through the first fabric, through one or more of the wavelength interchangers, and through the second fabric. Demands that do not require a change in wavelength are only routed through the third fabric. A  routing algorithm is utilized to ensure that any sequence of connection requests and withdrawals can be routed without disturbing any currently routed requests.
Patent CA-2368807-A1 (CA)
Inventor: MAGANO JAVIER
IPC: C07C211/56
Filed: 2000-02-16
Abstract: La présente invention concerne un procédé de préparation d'acides 2-(N-phénylamino)benzoïques, qui consiste à coupler un acide benzoïque et une aniline au moyen d'un hexaméthyldisilazide d'un métal alcalin que l'on utilise comme base.
Patent CA-2376893-A1 (CA)
Inventor: PREVOST JANY
IPC: E05F15/14
Filed: 2002-03-12
Abstract: The invention relates to a motorized locking device for a door intended in particular for a rail vehicle, with at least one leaf. The device includes a tilting-body motor intended to be mounted on the vehicle. The axis of the motor is substantially parallel to the longitudinal direction of movement of the leaf.
Patent CA-2377781-A1 (CA)
Title: Connection head for stereo headphone set
Inventor: ARMAND D TOUBOUL
IPC: H01R24/58
Filed: 2000-04-03
Abstract: The connection plug (1) has two pins (4, 5) of the jack type, one of the pins having two coaxial conductors (42, 44) and the second having three coaxial conductors (52, 55, 57). The head is arranged so as to be able to detach the part (3) containing the pin (4).
Patent CA-2378182-A1 (CA)
Inventor: FISHER KAREN L
IPC: C07K14/705
Filed: 2000-07-27
Abstract: L'invention concerne des compositions et procédés de diagnostic et de traitement de la croissance et prolifération cellulaires néoplasiques chez les mammifères, notamment chez l'homme. L'invention se base sur l'identification d'un gène ADAM8, amplifié dans le génome des cellules tumorales, une telle amplification génique étant associée à une surexpression du produit génique, par comparaison avec des cellules normales du même type de tissu, et contribuant à la tumorigenèse. En conséquence, la protéine ADAM8, codée par le gène amplifié, constitue une cible utile dans le diagnostic et/ou le traitement (y compris la prévention) de certains cancers, et elle agit en tant qu'indicateur du pronostic de traitement de la tumeur.
Patent CA-2378321-A1 (CA)
Inventor: BEZEMER JEROEN MATTIJS
IPC: C08K3/00
Filed: 2000-08-04
Abstract: La présente invention concerne un procédé de moulage d'un copolymère d'un téréphtalate de polyalkylène-glycol et d'un ester aromatique. A cet effet, on commence a) par préparer une solution du copolymère dans un premier solvant approprié, puis on b) forme un gel de la solution.
Patent CA-2379380-A1 (CA)
Inventor: OSAKI DAISUKE
IPC: C08K9/02
Filed: 2002-03-28
Abstract: Provided is a porous film which is excellent in a tear strength and has a low heat shrinkage. Such film is produced by subjecting to heat treatment on specific conditions, a porous film comprising a resin composition comprising: (a) a polypropylene base resin blend comprising 100 parts by weight of an ethylene-propylene block copolymer having a maximum peak temperature (Tm) of 140°C <= Tm <=  165°C which is given by differential scanning calorimetry (DSC), 3 to 40 parts by weight of low density polyethylene and 3 to 40 parts by weight of an ethylene-vinyl acetate copolymer, (b) calcium carbonate, (c) titanium oxide coated on a surface thereof with silica and/or alumina, (d) a hindered amine light stabilizer having a molecular weight of 1500 to 4500, (e) an ethyl ester phosphorous acid or biphenylene phosphonite antioxidant, and (f) a hindered phenol antioxidant, wherein the above resin composition comprises 100 to 200 parts by weight of (b)Ø5 to 20 parts by weight, of (c). 0.2 to 10 parts by weight of (d), 0.03 to 3 parts by weight of (e) and 0.05 to 3 parts by weight of (f) each per 100 parts by weight of (a). A laminate sheet comprising this polypropylene base porous film and a polyolefin base nonwoven fabric is excellent in a moisture permeability, a weatherability and a heat resistance.
Patent CA-2381079-A1 (CA)
Title: Outboard jet drive boat
Inventor: LAWSON WILLIAM
IPC: B63H11/08
Filed: 2000-08-09
Abstract: An outboard jet drive boat apparatus has a boat hull (11) having a transom (12) and having a removably attached outboard jet drive (10) attached to the transom (12). The outboard jet drive (10) includes a housing (13) sealed against the intrusion of water and has an engine mounting platform (14) therein having an engine (16) mounted thereon on flexible engine mounts (15).  The housing (13) has a sealable entrance through the top thereof and is removably attached to the transom (12). A jet drive unit (17) is attachedin the housing (13) below the engine supporting platform (14) andextending generally parallel to the engine (16) and extending from the front of the housing (13) out the rear of the housing (13).A main fuel tank (33) is positioned inside the hull (11) and is connected to a fuel line (35) to an auxiliary fuel tank (38) inside the housing (13) and the auxiliary fuel tank (38) is connected to the engine (16) for feeding fuel to the engine (16).
Patent CA-2381869-A1 (CA)
Title: Un produit souple et volumineux a epaisseurs multiples et methode de production
Inventor: SCHULZ GALYN A
IPC: B32B3/28
Filed: 2002-04-16
Abstract: L'invention concerne un mouchoir épais ultra-doux à multiples épaisseurs dont l'asymétrie globale est faible et la résistance moyenne à la rupture par traction est de moins de 800 g/3 po et où l'épaisseur gaufrée possède une asymétrie TMI d'au moins 0,45 et une section gaufrée d'au moins 2 pour 100 qui peut être faite d'une composition de moindre qualité. La méthode de fabrication de ces produits est dévoilée. Un mouchoir épais ultra-doux à multiples épaisseurs dont l'asymétrie globale est faible et la résistance moyenne à la rupture par traction est de moins de 35 g/3 po par lb de force du papier et où l'épaisseur gaufrée possède une asymétrie TMI d'au moins 0,45 et une section gaufrée d'au moins 2 pour 100 qui peut être faite d'une composition de moindre qualité. La méthode de fabrication de ces produits est dévoilée.
Patent CA-2383296-A1 (CA)
Inventor: GODBOUT GINETTE
IPC: A61K8/19
Filed: 2002-05-10
Abstract: L'invention concerne une composition sous forme de gel ou sous forme d'une suspension, pour l'amélioration de la santé et de la structure de toutes extensions chez les mammifères. Cette composition comprend au moins deux des composants suivants : un extrait d'au moins une algue; un extrait d'une plante de la famille Aloe Vera; une source de silice; et une source de cartilage. Cette composition est particulièrement utile pour améliorer la santé et la structure des ongles chez les humains.
Patent CA-2383893-A1 (CA)
Inventor: RIVENBURG HOWARD CHRISTOPHER
IPC: H02N1/00
Filed: 2000-09-11
Abstract: Cette invention concerne une particule chargée dont le passage d'une première électrode (9) à une deuxième électrode (10) est facilité par une électrode guide.
Patent CA-2385938-A1 (CA)
Title: Cyclic amine compounds as ccr5 antagonists
Inventor: BABA MASANORI
IPC: C07D487/14
Filed: 2000-09-29
Abstract: A compound of formula (I) (wherein R1 is a hydrogen atom, a hydrocarbon group which may be substituted, a non-aromatic heterocyclic group which may be substituted, R2 is a hydrocarbon group which may be substituted, a non-aromatic heterocyclic group which may be substituted, or R1 and R2 may combine to each other together with A to form a heterocyclic group which may be substituted;   A is N or N+-R5 .cndot.Y-(R5 is a hydrocarbon group; Y- is a counter anion); R3 is a cyclic hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; n is 0 or 1;  R4 is a hydrogen atom, a hydrocarbon group which may be substituted, a heterocyclic group which may be substituted, an alkoxy group which may be substituted, an aryloxy group which may be substituted, or an amino group which may be substituted, E is a divalent aliphatic hydrocarbon group which may be substituted by group(s) other than oxo; G1 is a bond, CO or SO2; G2 is CO, SO2, NHCO, CONH  or OCO; J is methine or a nitrogen atom;  and each of Q and R is a bond or a divalent C1-3 aliphatic hydrocarbon which may be substituted; provided that J is methine when G2 is OCO, that one of Q and R is not a bond when the other is a bond and that each of Q and R is not substituted by oxo group(s) when G1 is a bond) or a salt thereof has a potent CCR5 antagonistic activity and can be advantageously used for the treatment or prevention of infectious disease of various HIV in human (e.g. AIDS).
Patent CA-2386491-A1 (CA)
Inventor: MULDER DAVID G
IPC: H04L29/06
Filed: 2002-05-15
Abstract: A method for secure electronic information exchange between a sender and a recipient. The method includes generating a message at a first entity, generating a message encryption key, encrypting the message using the message encryption key, wrapping the message encryption key using a key agreement algorithm, generating a Java archive file including the encrypted message, the wrapped message encryption key and cryptographic algorithm code including decryption algorithm and key agreement algorithm code, encoding the Java archive file, embedding the encoded Java archive file in an HTML file, and sending the HTML file as an e-mail attachment to said recipient.
Patent CA-2386636-A1 (CA)
Title: 15-hydroxyeicosatetraenoic acid-related compounds and methods of use
Inventor: GRAFF GUSTAV
IPC: C07C59/42
Filed: 2000-10-23
Abstract: HETE derivatives and methods of their use for treating dry eye are disclosed .
Patent CA-2387557-A1 (CA)
Inventor: FALCIGLIA SAL SR
IPC: A63F1/00
Filed: 2002-05-27
Abstract: The method of the present invention involves a card game in which one or two rows of cards are dealt to a player. The player makes a wager to elect to play one or more sub-hands to be constructed from the one or two rows of cards dealt. In the basic game, sub-hands are constructed column-by-column whereby in a first column, a player selects none or one of the cards from the first column of the at least two rows of dealt cards for entry into a first sub-hand. The process is repeated for further elected sub-hands whereby the selection process is independent in each sub-hand. Additional cards are dealt from the deck for non-selected positions in the elected sub-hands. The poker hand ranking of each sub-hand is determined. The player is then paid for any winning poker hands based on a predetermined ranking table and the amount of the player's wager. In alternative versions of the game, when two rows of cards are dealt, the two rows may have a different number of cards; sub-hands may be constructed by means other than column-by-column; a player is given the option to interchange cards from the one or two rows with replacement cards.
Patent CA-2389268-A1 (CA)
Inventor: BJEL-DANES ERIK
IPC: C12Q1/68
Filed: 2000-11-22
Abstract: Methods are provided for quantitatively determining the amount of polynucleotides in a sample. In one method, the distinct polynucleotide targets and standard polynucleotide targets are contacted with detectable probes and independently detectable single or double stranded complements to the standard targets under hybridization conditions. The hybridization pattern from the probe is compared to the hybridization pattern from the standard sequences to obtain quantitative information about the genetic profile of the labeled nucleic acid sample. Also provided are kits for the use of the methods.
Patent CA-2389898-A1 (CA)
Inventor: XU HONGQUAN
IPC: G16B40/30
Filed: 2002-06-07
Abstract: A Smooth Response Surface (SRS) algorithm is provided as a more elaborate data mining technique for analyzing gene expression data, as well as computationally constructing a gene regulatory network. A three-dimensional smooth response surface is generated to capture the biological relationship between the target and activator-repressor. This novel technique is applied to functionally describe triplets of activators, repressors and targets, and their regulations in gene expression data. A diagnostic strategy is built into the SRS algorithm to evaluate the scores of the triplets so that those with low scores are kept and a regulatory network is constructed based on this information and existing biological knowledge. The predictions based on the identified triplets in two yeast expression data agree with experimental data in the literature. The invention provides a novel model with attractive mathematical and statistical features that make the algorithm valuable for mining expression or concentration information in gene expression analysis for determining the function of uncharacterized proteins, as well as for developing a more accurate understanding of coherent regulatory pathways.
Patent CA-2392814-A1 (CA)
Inventor: PAINTER ADRIAN RICHARD
IPC: C01B13/10
Filed: 2000-11-30
Abstract: A ventilation system has a water treatment section (54) which applies drople ts of water (58) to contaminated air. The water is then removed by an entrainme nt separator (62). The air is passed over a series of UV lamps (70) which generate ozone sufficiently fast to strip off the layer of ozone formed on t he UV tubes. Photolysis, ozonolysis and oxidation all reduce the level of organ ic contaminants in the air stream. The air then passes over a second UV source which decomposes any remaining ozone.
Patent CA-2394654-A1 (CA)
Inventor: KEENAN TERENCE P
IPC: C07F9/6561
Filed: 2000-12-18
Abstract: L'invention concerne des composés et des méthodes de traitement ou de prévention de troubles osseux, y compris l'ostéoporose, la polyarthrite rhumatoïde, et la maladie osseuse métastatique. Les composés de l'invention comprennent un fragment de ciblage du système osseux et une charge utile. La partie de charge utile de ces composés inhibent la pompe à protons des ostéoclastes, réduisant ainsi la résorption osseuse. Les composés de la présente invention comprennent des composés représentés par la formule (I).
Patent CA-2395605-A1 (CA)
Title: Video compression for multicast environments using spatial scalability and simulcast coding
Inventor: WAN WADE K
IPC: H04N7/26
Filed: 2000-04-10
Abstract: An optimal system for determining whether simulcast coding (400) or spatial scalability coding (100) should be used to encode video for clients with a specific communication link. Operating points (A', B', C') for both simulcas t coding and spatial scalability are also determined. Adaptive switching (3130 , 3140) is provided, with the operating points and decision boundaries being used to guide the switching to optimize the quality of the higher-resolution  data based on a bit allocation to the associated lower-resolution data. A system for determining the point (A', C') of equal quality in both layers of  simulcast and spatial scalability coding is also disclosed. The proportion o f bits allocated to the base layer to achieve equal quality is essentially independent of the total bit rate for both simulcast and spatial scalability .
Patent CA-2398516-A1 (CA)
Inventor: ROMERO ANGELINA PENA
IPC: C11D3/38
Filed: 2001-02-28
Abstract: Coated solid bodies comprising a core of an active composition and having a water-soluble or dispersible micro-porous or net-coating. The coating improv es the mechanical characteristics of the solid body and allows for good dissolution. The coated solid bodies preferably take the form of detergent tablets.
Patent CA-2399702-A1 (CA)
Inventor: RAPPAPORT STEPHEN A
IPC: G09B19/00
Filed: 2001-02-09
Abstract: An apparatus and method for analysis involving a first factor (40) and a second factor (42). The first and second factors (42) are related as expressed by a first relationship. The apparatus comprises a base (32) divided into first (40), second (42) and third (44) sections, where the second section (42) is positioned between the first (40) and third sections (44). The first (40), second (42) and third sections (44) are representative of the first factor (40), the first relationship and the second factor (42), respectively. The method of the present invention involves the steps of providing the apparatus and engaging a dialogue of questions related to both the first and second factors (42).
Patent CA-2401738-A1 (CA)
Title: Network resource communication system
Inventor: HOLLANDER BRIAN
IPC: H04L12/24
Filed: 2001-03-01
Abstract: A network resource communication system facilitates communication over a network between network terminals and network resources, and comprises a network resource driver, a driver administrator, and a data transmitter. The  network resource driver facilitates communication of source data between the  network terminals and one of the network resources, and includes a driver input for receiving the source data and a driver output for providing a translation of the source data in accordance with the network resource. The driver administrator is in communication with a resource registry, and includes resource records associated with the network resources. The resourc e records define at least a resource type for each network resource, and the driver administrator is configured to configure the network resource driver in accordance with the resource record associated with the network resource. Th e data transmitter is in communication with the driver output for transmitting  the translated data to the network resource.
Patent CA-2402188-A1 (CA)
Inventor: PODSZUN WOLFGANG
IPC: C08F2/38
Filed: 2001-02-26
Abstract: La présente invention concerne de nouveaux polymères en perles, réticulés, qui présentent une taille particulaire moyenne allant de 1 à 1000 ?m et qui contiennent des composés phosphorés spéciaux, exempts d'halogène. La présente invention concerne également un procédé de production de ces polymères en perles, ainsi que leur utilisation en tant qu'agents ignifugeants dans des matières thermoplastiques.
Patent CA-2402523-A1 (CA)
Title: Rail pad & method for strain attentuation
Inventor: MCQUEEN PHILIP JEFFREY
IPC: E01B9/68
Filed: 2002-10-09
Abstract: An apparatus for use as a pad and for placement intermediate a rail and a railroad tie includes a plurality of geometrical recesses that extend into the pad, either at a normal longitudinal axis or at an angle other than normal.    An elastomeric material is used to form the pad. The recesses may include any geometric shape in plan at the surface of the pad. If desired, a tiered structure, is provided for any of the recesses. According to a modification, any of the recesses are modified to include a longitudinal axis that is not normal. The modified recesses include any geometrical, polygonal, circular, or oval shape in plan at the surface of the pad.
Patent CA-2404439-A1 (CA)
Title: Diphenyl ether compounds useful in therapy
Inventor: ANDREWS MARK DAVID
IPC: C07C237/28
Filed: 2001-03-19
Abstract: A compound of general formula (I), or pharmaceutically acceptable salts, solvates or polymorphs thereof; wherein R3 is independ ently CF3, OCF3, C1-C4alkylthio or C1-C4alkoxy; n is 1, 2 or 3; and the other variables are as defined in the claims. These compounds inhibit monoamine re-uptake and in particular exhibit activity as selective serotonin re-uptake inhibitors. They are useful in disorders such as depression, attention deficit hyperactivity disorder, obsessive-compulsive disorder, post-traumatic stress disorder, substance abuse disorders and sexual dysfunction including premature ejaculation.
Patent CA-2404673-A1 (CA)
Inventor: LOTZ WILLIAM H
IPC: F25D23/02
Filed: 2002-09-23
Abstract: A refrigerator handle assembly includes a base plate which is initially attached to the face of the refrigerator, such as through the use of screws or the like. The base plate includes tapered surfaces, preferably at longitudinally spaced positions. Once the base plate is secured, a portion of the handle is placed over the base plate and slid relative to the base plate whereupon the tapered surfaces coact with structure on the handle such that an interference fit is developed to draw the handle tight to the face of the door. With the handle in this position, one or more mechanical fasteners are driven into a body portion of the handle from a back side of the door.
Patent CA-2409252-A1 (CA)
Title: Clinker sulfoalumineux sans fer et sans chaux libre, son procede de preparation et son utilisation dans des liants blancs
Inventor: COLOMBET PIERRE
IPC: C04B28/06
Filed: 2002-10-21
Abstract: Le clinker sulfoalumineux faiblement coloré renferme - plus de 55 % en poids de phase sulfoaluminate de calcium (C4A3 S~) - plus de 10 % en poids de phase bélite (C2S) - moins de 10 % en poids d'anhydrite (C S~) et ne renferme pratiquement pas de phase ferrite, ni de phase gehlénite (C2AS), ni de chaux libre.  Il est préparé par un procédé de clinkérisation réalisé à des températur es comprises entre 1.250.degree. C et 1.350.degree. C environ. Il peut être utilisé pour une large gamme d'applications en le combinant à u ne source de sulfate de calcium et/ou du ciment Portland, pour obtenir des lian ts ayant des propriétés spécifiques (couleur, temps de prise, résistance mécanique, expansion ou retrait...).