baber/WOPTO huggingface dataset:
Patent CA-2561868-C (CA)
Inventor: LEAKE DEVIN
IPC: C07H21/02
Filed: 2005-03-31
Granted: 2012-11-06
Abstract: Methods and compositions for performing RNA interference with decreased off-target effects are provided. The methods and compositions permit effective and efficient applications of RNA interference to applications such as diagnostics and therapeutics through the use of modifications to the siRNA. Uniquely modified siRNAs have been developed that reduce off-target effects incurred in gene-silencing. The modifications comprise 2'-O-alkyl or mismatch modification(s) at specific positions on the sense and/or antisense strands.
Patent CA-2563462-C (CA)
Title: Device for the analysis of elements
Inventor: KLEIN ALBERT
IPC: G01N23/223
Filed: 2005-04-15
Granted: 2014-04-01
Abstract: Disclosed is a device for analyzing elements, by means of which precise measurements can be taken also in unfavorable environmental conditions. In order to do so, said device comprises a conveying means which is provided with a measurement zone (14) and is used for conveying the substance (S) that is to be measured, a source of excitement encompassing a discharge window located in a first housing (22), and an X-ray fluorescence detector (30) which is oriented towards the measurement zone (34) and is equipped with a delivery window (34) located in a second housing (32). In order to minimize air absorption and prevent dust and dirt from depositing, a tube (40, 50) extends from the delivery window (34) and/or from the discharge window (24) in the direction of the measurement zone, said tube (40, 50) being joined to the respective housing (22, 32) in a substantially tight manner while being open at the end facing the measurement zone, and a connection (44,54) for feeding a purge gas into the interior of the tube.
Patent CA-2563565-C (CA)
Title: Easily-cleaning multifunctional soyabean milk maker
Inventor: WANG XUNING
IPC: A47J43/044
Filed: 2005-11-28
Granted: 2008-08-05
Abstract: An easily-cleaning multifunctional soybean milk maker comprises a motor, a blade, a head unit, and a container, wherein a lower cover of the head unit being capped on the container, characterized in that a flow guider is securely fastened to the lower cover of the head unit, with the lower part of the flow guider immersed into water and the lower port of the flow guider being open. The blade fastened at the front end of the motor shaft is arranged within the flow guider and extends into water. Guiding holes are provided in the flow guider, and/or guiding channels in communication with the interior of the flow guider are provided on the lower cover of the head unit.
Patent CA-2564800-C (CA)
Inventor: ANEX DEON S
IPC: A61M5/148
Filed: 2005-04-21
Granted: 2014-04-15
Abstract: Devices, systems and methods according to the present invention utilize electrokinetic pumps capable of generating high and low pressures flow for various medical applications, including drug delivery and analyte sampling.  The EK pumps and systems are configured and constructed to be low cost, compact and precise.
Patent CA-2566461-C (CA)
Title: Pyrrole compounds as inhibitors of erk protein kinase, synthesis thereof and intermediates thereto
Inventor: MARTINEZ-BOTELLA GABRIEL
IPC: C07F9/58
Filed: 2005-05-13
Granted: 2012-07-10
Abstract: The present invention provides a compound of formula I:  (see formula I) or a pharmaceutically acceptable salt thereof.     The compound or salt may be used to inhibit ERK1 or ERK2 protein kinase activity in a biological sample in vitro or treat or lessen the severity of melanoma, breast cancer, colon cancer, pancreatic cancer, kidney carcinoma, lung cancer, ovarian cancer or prostate cancer in a patient in need thereof.
Patent CA-2568631-C (CA)
Title: Roller element
Inventor: REIST WALTER
IPC: F16C29/06
Filed: 2005-05-20
Granted: 2014-07-15
Abstract: A roller element comprises a central body as well as a roller unit. The roller unit is arranged on a non-circular continuous track extending around the central body and movable relative to the central body by rollers of the roller unit rolling-off on the central body. The rollers are designed as balls or essentially roller-shaped, a circumferential surface of the rollers is for a substantial part shaped as a rolling surface corresponding with the central body and shaped for rolling-off on the central body, and the roller unit as such and/or in its mobility relative to the central body comprises play. In preference, the roller unit comprises means for achieving an unchanging spacing between the rollers, which is at least a flexible bearing belt, which connects bearing axles of the rollers together.
Patent CA-2571224-C (CA)
Inventor: YOKOTANI HITOSHI
IPC: F16H61/32
Filed: 2006-12-15
Granted: 2010-03-30
Abstract: To provide an internal combustion engine capable of being reduced in size by making a contrivance as to the layout of a speed change drive mechanism including a speed change electric motor. An internal combustion engine including a transmission for transmitting power from a crankshaft to an output shaft through speed change, with the speed change in the transmission being performed by the driving of a speed change electric motor through a speed change drive mechanism, wherein power transmission control means for controlling the transmission of power from the crankshaft to the transmission is provided at one end of the crankshaft, and at least a part of the speed change electric motor and the speed change drive mechanism is disposed on the outside of the power transmission control means.
Patent CA-2572966-C (CA)
Title: Configurable multi-level thermostat backlighting
Inventor: PROFFITT JERRY L
IPC: G05D23/00
Filed: 2005-08-31
Granted: 2010-06-29
Abstract: A thermostat includes a display and an illumination device that is configurable to illuminate the display in a partial illumination mode and full illumination mode. In the partial illumination mode the illumination device generates a light intensity sufficient to review the settings of the thermostat without generating heat of a sufficient amount to disrupt thermostat measurements. The full illuminated condition is actuated upon interaction with the thermostat. Once interaction with the thermostat is completed the illumination device thermostat returns to the partially illuminated condition.
Patent CA-2577199-C (CA)
Inventor: LOBERG BARRIE A
IPC: G06F17/50
Filed: 2005-08-17
Granted: 2015-12-22
Abstract: A software program for use in designing interior and exterior spaces receives user input that is associated with one or more attributes. After receiving a different user input that changes at least one of an initial or subsequent attributes automatically displaying the initial and subsequent user input as originally received. Design choices that conflict with prior design choices are resolved to ensure that each of the prior and present user input choices are represented in an appropriate way. The resolution by the design software is also used to create an accurate parts (and/or price) list so that when the user has completed the design of an exterior or interior space, the design can be submitted directly as an order to be fulfilled. Generally, continual resolution ensures that the user's design intent is captured in an accurate and efficient way in a user interface.
Patent CA-2577214-C (CA)
Inventor: FRYZEK AARON P
IPC: H01R9/05
Filed: 2007-02-06
Granted: 2014-04-22
Abstract: A connector is provided for electrically connecting a coaxial cable having a conductive inner wire surrounded by a conductive outer jacket and an insulator therebetween to a two-wire circuit. The connector comprises a conductive bottom contact member having a first passageway dimensioned to fit only the inner wire and the insulator therethrough and to block the conductive outer jacket. A conductive top contact member has a second passageway for the inner wire and the insulator and a clamping member for securing the inner wire to the top contact member. An insulating member for electrically separates the bottom contact member from the top contact member. A pendant-style light fixture using the coaxial connector is also disclosed.
Patent CA-2577634-C (CA)
Inventor: JONAS MARCO
IPC: C07D233/02
Filed: 2005-07-19
Granted: 2015-07-07
Abstract: Methods and intermediates for synthesizing triethylenetetramine and salts thereof, as well as novel triethylenetetramine salts and their crystal structure, and triethylenetetramine salts of high purity.
Patent CA-2579814-C (CA)
Title: Constituant de charge pour des suspensions de moulage de precision
Inventor: DOLES RONALD S
IPC: B22C1/02
Filed: 2005-07-27
Granted: 2014-03-11
Abstract: La présente invention a trait à un constituant de charge pour une suspension de moulage de précision, comportant: une portion majoritaire de silice, de silicate d'alumine, d'alumine, de zircon finement divisés, ou des mélanges de ceux-ci, et une portion minoritaire d'une ou de plusieurs matières finement divisées ayant des particules dans lesquelles, en moyenne, au moins une dimension de la particule est au moins quatre fois supérieure à celle d'au moins une autre dimension de la particule. De manière caractéristique, les particules présentent une forme globale de feuillet ou d'aiguille.
Patent CA-2582088-C (CA)
Inventor: CUNNINGHAM DAVID D
IPC: A61B5/151
Filed: 1997-12-04
Granted: 2011-11-15
Abstract: A nosepiece suitable for use with a blood collection apparatus, said nosepiece comprises: (i) a lower base having an opening therein; (ii) an upper base having an opening therein; and (iii) an interior wall joining said upper base and said lower base, the area of said opening in said upper base being equal to or less than the area of said opening in said lower base; the nosepiece is suitable for use in a method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. One such method comprises the steps of: (a) forming an unobstructed opening in the area of the skin from which the sample of blood is to be extracted; and (b) extracting the sample of blood from the unobstructed opening in the skin, with the aid of a vacuum and a stretching of the skin. One such apparatus comprises: (a) a device for forming an unobstructed opening in an area of skin from which said sample is to be extracted, preferably a lancing assembly; and (b) a vacuum pump.  Preferably, the apparatus also includes a housing. A pneumatic lancing assembly is also provided. The pneumatic lancing assembly uses differential gas pressure to thrust a lancet into skin tissue. In another aspect of this invention, an article is provided for an article capable of both collecting blood and detecting an analyte in that blood. The article, which contains an appropriate detection element for determining the amount of analyte in the blood, can be used in conjunction with a meter that measures the signal generated by the detection element of the article.
Patent CA-2583777-C (CA)
Title: Produit de polycondensation a base de composes aromatiques ou heteroaromatiques, procede de production et utilisation de ce produit
Inventor: WIELAND PHILIPP
IPC: C04B24/30
Filed: 2005-10-14
Granted: 2013-01-15
Abstract: L'invention concerne un produit de polycondensation comprenant A) un composé aromatique ou hétéroaromatique comportant 5 à 10 atomes ou hétéroatomes de carbone, ce composé présentant en moyenne par molécule 1 à 300 groupes d'oxyéthylène et/ou d'oxypropylène qui sont liés au composé aromatique ou hétéroaromatique par un atome d'oxygène ou d'azote, et éventuellement B) un composé aromatique choisi dans le groupe comprenant les phénols, les éthers phénoliques, les naphtols, les éthers naphtoliques, les anilines, les alcools furfuryliques et/ou un agent de formation d'aminoplastes choisi dans le groupe comprenant la mélamine ou ses dérivés, l'urée ou ses dérivés et les carboxamides et C) un aldéhyde choisi dans le groupe comprenant le formaldéhyde, l'acide glyoxylique et le benzaldéhyde ou des mélanges de ceux-ci, le benzaldéhyde pouvant présenter également des groupes acide sous la forme de COOMa, SO3Ma et PO3Ma, M représentant un hydrogène, un métal alcalin ou alcalinoterreux, un ammonium ou des groupes amine organiques et a étant égal à 1/2, 1 ou 2. De façon surprenante, il s'avère que le produit de polycondensation selon l'invention permet d'obtenir une excellente fluidification des liants hydrauliques, tels que le ciment. Comparativement aux sulfonates de naphtaline ou de mélamine, il entraîne une fluidification du matériau de construction nettement meilleure tout en permettant de réduire le dosage, la fluidité pouvant être maintenue sur une période prolongée.
Patent CA-2586188-C (CA)
Inventor: ACKERMANN FRIEDRICH
IPC: H04L12/28
Filed: 2007-04-24
Granted: 2013-01-29
Abstract: Apparatuses and methods thereof to administer and manage a base unit for a handheld medical device are disclosed. In one embodiment, a base unit of the invention is in communication with a handheld medical device. The base unit is configured to provide an electrical connection to a power source to charge a battery of the handheld medical device. The base unit is also configured to perform an update to the operation of the base unit, wherein the update is initiated by the base unit upon receiving from the handheld medical device a data stream with information indicating that an update is contained in the data stream.
Patent CA-2592109-C (CA)
Title: Automated pharmacy admixture system (apas)
Inventor: ROB RONALD H
IPC: G16H20/13
Filed: 2005-12-22
Granted: 2014-09-23
Abstract: An Automated Pharmacy Admixture System (APAS) may include a manipulator that transports medical containers such as bags, vials, or syringes about a substantially aseptic admixing chamber. In a preferred implementation, a gripper assembly is configured to substantially universally grasp and retain syringes, IV bags, and vials of varying shapes and sizes. In an illustrative embodiment, a gripping device may include claws configured to grasp a plurality of different types of IV bags, each type having a different fill port configuration. Embodiments may include a controller adapted to actuate a transport assembly to place a fill port of the bag, vial or syringe into register with a filling port such as a cannula located at a filling station, or be equipped with carousel transport systems that are adapted to convey bags, vials, and syringes to the admixture system and deliver constituted medications in bags, vials or syringes to an egress area.
Patent CA-2593282-C (CA)
Inventor: ABO MASANOBU
IPC: C12P7/64
Filed: 2006-01-10
Granted: 2016-03-15
Abstract: A method for producing fatty acid alkyl esters, wherein a solution comprising triglyceride and alcohol is contacted with a first lipolytic enzyme having a relatively higher activity on free fatty acids than on triglyceride and a second lipolytic enzyme having a relatively higher activity on triglyceride than on free fatty acids.
Patent CA-2594930-C (CA)
Title: Procede de production de composes d'acide aminoalkylenephosphonique en presence d'un catalyseur heterogene
Inventor: NOTTE PATRICK P
IPC: C07F9/38
Filed: 2005-11-07
Granted: 2013-04-02
Abstract: La présente invention se rapporte à un procédé avantageux permettant de produire des acides aminopolyalkylènephosphoniques, en l'absence pour ainsi dire totale d'acide hydrohalogénique. Le procédé consiste essentiellement à faire réagir des proportions précisément définies d'un acide phosphoreux, d'une amine et d'un formaldéhyde, en présence d'un catalyseur acide de Broensted. Le procédé selon l'invention présente des avantages importants sur le plan économique, et sur le plan qualitatif, fonctionnel et de la capacité de production ; il permet en particulier de réduire sensiblement la durée du cycle à une étape en excluant les inconvénients liés à la corrosion, et est sans danger pour l'environnement car il ne nécessite rien d'autre que les dépenses de capital nominal.
Patent CA-2596595-C (CA)
Inventor: JAFFRAY DAVID
IPC: A61B8/00
Filed: 2006-02-10
Granted: 2014-12-16
Abstract: Provided are signal modifying compositions for medical imaging comprising a carrier and two or more signal modifying agents specific for two or more imaging modalities. The compositions are characterized by retention efficiency, with respect to the signal modifying agents, which enables prolonged contrast imaging without significant depletion of the signal modifying agents from the carrier. The carriers of the present invention are lipid based or polymer based, the physico-chemical properties of which can be modified to entrap or chelate different signal modifying agents and mixtures thereof and to target specific organs or tumors or tissues within a mammal.
Patent CA-2598305-C (CA)
Title: Ion mobility spectrometer
Inventor: FUHRER KATRIN
IPC: G01N27/64
Filed: 2006-02-13
Granted: 2010-07-13
Abstract: The present invention relates to an improved ion mobility spectrometer and method for the analysis of chemical samples. The improvements are realized in the optimization of resolution and sensitivity. Increases in sensitivity are realized by preserving a narrow spatial distribution of migrating ions through the use of periodic/hyperbolic field focusing. Use of a plurality of drift cells and a new RF field focusing interface are discussed.
Patent CA-2604904-C (CA)
Title: Preparations de collagene antiseptiques a autosterilisation, leur utilisation et procede pour leur production
Inventor: ALUPEI JULIAN CORNELIU
IPC: C08L89/06
Filed: 2006-04-18
Granted: 2013-09-24
Abstract: L'invention concerne un procédé pour la stérilisation de préparations de collagène et la production de préparations de collagène antiseptiques à autostérilisation, leur utilisation pour produire des produits au collagène comme des éponges, des films ou des gels, notamment à des fins médicales et/ou cosmétiques, ainsi que les produits fabriqués à partir de ces préparations de collagène à autostérilisation.
Patent CA-2605965-C (CA)
Title: Composite discharge electrode
Inventor: ALAM M KHAIRUL
IPC: B03C3/41
Filed: 2006-04-19
Granted: 2012-01-03
Abstract: The invention is a discharge electrode (20, 22, 24) in an electrostatic precipitator having a power supply (30) connected to at least one collection electrode (12, 14, 16) and a flow of gas across the collection electrode (12, 14, 16). The discharge electrode (20, 22, 24) has a plurality of conductive fibers electrically connected to the power supply (30) and fiber tips exposed to the flow of gas. The fiber tips preferably extend from a composite in which the fibers reinforce a matrix material, but alternatively can be a large number of filaments (72) extending from a composite rod (70).
Patent CA-2606892-C (CA)
Title: Flexible optical rf receiver
Inventor: O'SHEA RICHARD L
IPC: H02J50/30
Filed: 1999-07-06
Granted: 2010-09-28
Abstract: An array antenna is constructed of radiators disposed upon a flexible substrate wherein a plurality of receiving circuits connect with respective ones of the radiators for conversion of RF (radio frequency) signals, received by the radiators, are converted into IF (intermediate frequency) signals. The signals outputted by the receiving circuits may be applied to a beamformer for generating a receive beam from the array. The receiving circuits have an elongated flexible form to permit bending of the array to have a desired configuration. All power for operating the receiving circuits and all signal paths to and from the receiving circuits are accomplished via optical fibers. Photocells are provided within the receiving circuits for conversion of optical power to operating electric power. Photodetectors within the receiving circuits provide for conversion of optical reference signal to electrical reference signals An optical modulator within each of the receiving circuits provides for conversion of an outputted electric signal to an output optical signal for transmission via an output optical fiber. In each of the receiving circuits, a mixer provided for conversion between RF and IF is operative without a bias voltage.
Patent CA-2614375-C (CA)
Inventor: SUSLOV NICKOLAY
IPC: H05H1/28
Filed: 2006-07-07
Granted: 2014-09-02
Abstract: The present invention relates to a plasma-generating device, comprising an anode, a cathode and at least one intermediate electrode, said intermediate electrode being arranged at least partly between said anode and said cathode, and said intermediate electrode and said anode forming at least a part of a plasma channel which has an opening in said anode. Further, the plasma-generating device comprises at least one coolant channel which is arranged with at least one outlet opening which is positioned beyond, in the direction from the cathode to the anode, said at least one intermediate electrode, and the channel direction of said coolant channel at said outlet opening has a directional component which is the same as that of the channel direction of the plasma channel at the opening thereof. The invention also concerns a plasma surgical device and use of such a plasma surgical device.
Patent CA-2616754-C (CA)
Inventor: DOPPSTADT JOHANN
IPC: B02C23/16
Filed: 2007-04-25
Granted: 2014-03-11
Abstract: The invention refers to a comminution device comprising at least one comminution cylinder supported rotating in a machine frame with at least one comminution tool arranged on it, and at least one counter cutter interacting with the comminution tool, and at least one sieve device for the comminuted material the housing of which encircles the comminution cylinder at least partly, the sieve device and the counter cutter forming a common structural component. The invention is characterised in that the counter cutter is designed like a plate and has recesses designed corresponding to the shape of the comminution tools of the comminution device.
Patent CA-2632387-C (CA)
Inventor: STANGL WOLFGANG
IPC: B28D5/00
Filed: 2006-12-06
Granted: 2012-04-17
Abstract: L'invention concerne un dispositif de nettoyage d'un bloc scié (40) de galettes semi-conductrices, qui présente une cuve de nettoyage (10), un support (50, 52) qui maintient un bloc scié (40) de galettes semi-conductrices dans la cuve de nettoyage (17) de sorte que lorsqu'un liquide de nettoyage (34) est présent dans la cuve de nettoyage (10), au moins une partie du bloc (40) de galettes semi-conductrices qui présente des interstices de sciage soit disposée dans le liquide de nettoyage, au moins une ouverture de sortie (18) située dans la zone du fond (16) de la cuve de nettoyage (10) et un dispositif de fermeture (20, 22) de l'ouverture de sortie (18) qui permet d'ouvrir et de fermer l'ouverture de sortie (18). Le dispositif de fermeture (20, 22), l'ouverture de sortie (18) et la zone du fond de la cuve de nettoyage sont conçus de telle sorte que l'ouverture du dispositif de fermeture (20, 22) permet d'évacuer le liquide de nettoyage au moins de la partie de la cuve de nettoyage (10) dans laquelle le bloc de galettes semi-conductrices est disposé, et ce suffisamment rapidement pour pouvoir éliminer les impuretés hors des interstices de sciage par un effet d'aspiration du liquide de nettoyage.
Patent CA-2633444-C (CA)
Inventor: EKEROTH JOHAN
IPC: B01J20/286
Filed: 2006-12-11
Granted: 2012-07-17
Abstract: An organo-modified silica based material to be used for making a stationary phase for liquid chromatography comprising a part which is unmodified silica, and a part 5 which is silica comprising organic groups bonded to the silica. A method for preparing an organo-modified silica based material comprising mixing in an aqueous medium a silica based material and an organosilane compound, and reacting the mixture. A stationary phase separation material prepared by functionalising the organo-modified silica based material is also disclosed.