baber/WOPTO huggingface dataset:
Patent EP-2068938-A2 (EP)
Inventor: GATHMANN INSA
IPC: A61P35/02
Filed: 2007-09-20
Abstract: The present invention provides a method of treating Philadelphia positive (Ph+) leukemia, such as Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL) or chronic myeloid leukemia (CML), in a human patient population comprising the steps of 
(a) administering a predetermined fixed amount of a Bcr-Abl tyrosine kinase inhibitor, such as Imatinib, or a pharmaceutically acceptable salt thereof to human patients suffering from a Ph+ leukemia, 
(b) collecting at least one blood sample from said patients, 
(c) determining the plasma trough level (Cmin) of the Bcr-Abl tyrosine kinase inhibitor or of a metabolite thereof as well as the MMR rates, 
(d) assessing a discrimination potential of trough plasma concentrations for MMR and identifying a Cmin threshold for optimal sensitivity and specificity and 
(e) adjusting the dose of the inhibitor of the Bcr-Abl tyrosine kinase or a pharmaceutically acceptable salt thereof applied to the individual patients from said patient population and, optionally, future patients suffering from a Ph+ leukemia in a manner that a Cmin is achieved in each single patient equal to or higher than the Cmin threshold obtained under step (d).
Patent EP-2089772-A2 (EP)
Inventor: LEVINSON HARRY J
IPC: G03F7/20
Filed: 2007-11-29
Abstract: Un mode de réalisation donné à titre d'exemple est un procédé (500) permettant de détecter l'existence d'une particule indésirable (122) entre un objet lithographique planaire, tel qu'une tranche de semi-conducteur (102) ou un masque lithographique (202), et un support individuel de tranche (104) au cours de la fabrication d'un semi-conducteur. Le procédé donné à titre d'exemple selon ce mode de réalisation inclut l'étape consistant à placer (504) l'objet lithographique planaire, tel que la tranche de semi-conducteur (102), sur le support individuel de tranche. Le procédé inclut en outre l'étape consistant à mesurer un changement dans au moins une caractéristique électrique formée par et entre le support individuel de tranche et l'objet lithographique planaire, comme mesurer (506) un changement de capacitance entre le support individuel de tranche (104) et la tranche de semi-conducteur (102), causé par une particule indésirable.
Patent EP-2083881-A2 (EP)
Inventor: BALSCHAT KLAUS
IPC: A61M1/34
Filed: 2007-10-22
Abstract: The invention relates to the field of renal replacement therapy devices. It was found that the connections (14, 15, 101) already present in a hemodialysis or hemodiafiltration device (10) for connection to a hemodialysis device or for providing a substitute liquid can be directly used for taking samples which are required for regular microbiological tests. The invention does not require additional components on the device or laborious sanitary measures to avoid secondary contaminations. Samples can simply be taken by connecting the sterile sampling kit according to the invention. On the device side, it is only necessary to program the control unit (26) to carry out the method according to the invention by controlling closing elements (20, 21, 103) and pump devices (17, 18) in the context of a sampling control program.
Patent EP-2046631-A2 (EP)
Inventor: DAVIS GREGORY A
IPC: B63G9/04
Filed: 2007-07-30
Abstract: Système destiné à protéger les structures dans un environnement marin contre les effets d'une force d'impact. Le système comprend une pluralité de dispositifs flottants (panneaux) et une pluralité de réseaux fibreux. Les réseaux fibreux comprennent des fibres haute ténacité qui s'étendent au moins dans une direction généralement horizontale et sont en communication avec plusieurs panneaux flottants. Les différents réseaux fibreux sont disposés selon une disposition généralement parallèle les uns aux autres et sont verticalement espacés d'une distance qui ne dépasse pas environ 12 pouces (30,5 cm). Le système est conçu pour être éloigné de la structure à protéger.
Patent EP-2095117-A2 (EP)
Inventor: WINTHER LARS
IPC: G01N33/48
Filed: 2007-11-29
Abstract: La présente invention porte sur des systèmes de réactifs et sur des procédés pour la détection de cibles chimiques et biologiques dans un échantillon. Certains modes de réalisation comprennent des procédés pour sélectionner automatiquement un ensemble de réactif pour détecter une ou plusieurs cibles dans un échantillon. L'ensemble de réactifs comprend au moins deux couches pour la détection d'une première cible, et au moins deux couches pour la détection d'une seconde cible, l'ensemble comprenant des réactifs qui sont au moins partiellement redondants. Dans certains modes de réalisation, la redondance est créée par au moins un réactif dégradé de telle sorte que le réactif peut interagir spécifiquement avec plus d'un autre composant d'un système de détection ou d'un échantillon. Dans certains modes de réalisation, le système ou le procédé comprend également des récipients de réactifs avec un code généré par ordinateur qui peut en outre servir à mettre en correspondance des cibles avec des réactifs appropriés.
Patent EP-1935427-A2 (EP)
Inventor: COHEN ROBERT
IPC: A61K38/16
Filed: 2001-07-02
Abstract: The present invention relates to compositions and methods for treating rheumatic disease by administering to a subject, soluble CTLA4 mutant molecules that block endogenous B7 molecules from binding their ligands.
Patent EP-2016841-A2 (EP)
Inventor: BACHMANN CHARLES
IPC: A24F17/00
Filed: 2008-06-09
Abstract: Rolling papers and apparatus for holding rolling papers are provided, In one aspect of the invention, a stack of individually removable rolling papers is provided, the stack including a spine (2, 22, 32), an initial sheet (18) disposed on the spine (2, 22, 32), an end sheet (19) disposed on the spine (2, 22, 32), and a plurality of sheets (20) disposed on the spine (2, 22, 32) between the initial sheet (18) and the end sheet (19) with each of the initial sheet (18) , the end sheet (19), and the plurality of sheets (20) therebetween having an adhesive (4, 24, 34) disposed thereon and the adhesive (4, 24, 34) is coupled to the spine (2, 22, 32) to define a gummed edge (7), and the spine (2, 22, 32) separates each of the gummed edge (7) from a proceeding gummed edge (7).
Patent EP-2009337-A2 (EP)
Inventor: ZIMMERMANN DIRK
IPC: F28F9/013
Filed: 2008-06-26
Abstract: The arrangement has a holding device (2) placed in contact with a corrugated pipe (1) by a point (3) of a shell surface, where the corrugated pipe lies in a recess (4) of the holding device that fixes the corrugated pipe in a specific direction. The recess and/or a meander-shaped curve of the holding device exhibits an opening width, which is smaller than a shell diameter of the corrugated pipe at a fastening position.
Patent EP-1990282-A2 (EP)
Inventor: PAUL CHARLES W
IPC: B29B13/02
Filed: 2001-10-31
Abstract: Films having a melting point below about 100°C are used to package low temperature hot melt adhesives. The packaging film does not require removal prior to use of the adhesive. The packaged adhesive is easy to handle and units are non-blocking.
Patent EP-2036847-A2 (EP)
Inventor: CORRES NORBERT
IPC: B65H67/08
Filed: 2008-08-30
Abstract: The method involves providing a finger thread guide (13) for traversing a thread accumulated on a textile spool, where the thread guide is provided with magnetic energy storage and drives a single motor. A suction nozzle (17) is provided and pivoted for grabbing a thread end in a region of surface of the textile spool. The finger thread guide is positioned and locked in an end position in a form fit manner, before the suction nozzle engages a thread end accommodation position (I). An independent claim is also included for a device for performing a method for operating a spooling station of a textile machine, which produces cross-wound spool.
Patent EP-2073592-A2 (EP)
Inventor: MENSING CHRISTIAN
IPC: H04W4/90
Filed: 2008-11-08
Abstract: The method involves causing or coordinating transmission of modified signal structures (MS1-MS3) with pilot symbols of base stations (B1-B3) with adjusted high power by the base stations of a backbone network (BB). Transmission power of signals and/or signal components is adjusted in the base stations in such a manner that the signals and/or signal components comprise different base stations at a mobile communication terminal (KE) of similar level, where the signals are modified by pilot symbols.
Patent EP-2062918-A2 (EP)
Inventor: NEUFELD GERA
IPC: C12Q1/68
Filed: 2003-11-27
Abstract: Methods and compositions suitable for modulating angiogenesis in a mammalian tissue are provided. Further provided are methods suitable for inhibiting metastasis and fibrosis in a mammalian tissue and for assessing the malignancy of colon cancer tumors.
Patent EP-1933470-A2 (EP)
Inventor: LOMP GARY
IPC: H04B17/00
Filed: 1996-06-27
Abstract: A method for transferring voice and non-voice data in a wireless communication system, the method comprising receiving, during a time period, a voice data block associated with a first logical channel, when the voice data block is present in a wireless channel set during a time period, wherein the wireless channel set comprises at one wireless channel or a plurality of wireless channels; receiving a non-voice data block associated with a second logical channel, when the non-voice data block is present in the wireless channel set during the time period, wherein the wireless channel set is associated with a subscriber unit, and when the non-voice data block is missing in the wireless channel set, information is inserted into a non-voice block; and processing the information in the non-voice block.
Patent EP-1980820-A2 (EP)
Inventor: SATOH KIYOHIDE
IPC: G01B11/26
Filed: 2008-04-11
Abstract: An orientation measurement value acquisition unit (145) acquires an orientation measurement value measured by an orientation sensor (110) mounted on an image capturing apparatus (120), and an orientation measurement value measured by a sensor (115) mounted on a physical object (125). An image processing unit (135) acquires the image coordinates, on a captured image, of indices allocated on the physical object (125). A calibration unit (160) calculates at least one of allocation information of the sensor (110) with respect to the image capturing apparatus (120) and allocation information of the sensor (115) with respect to the physical object (125) using the two orientation measurement values and image coordinates.
Patent EP-1953760-A2 (EP)
Inventor: JUNG KIL-SOO
IPC: G11B27/10
Filed: 2005-02-19
Abstract: A method for storing text-based subtitle data including style information. The method includes reading text-based subtitle data (120) including dialog information (820) and style set (810). The dialog information (820) comprises text information (534), reference style information (532) and partial style information (536). The style set (810) comprises a plurality of style information (512,522) and information (830) on whether predetermined style information, which is separate from the style information defined by a manufacturer of the storage medium, should be applied to the dialog information (530). The method also includes applying the predetermined style information to the dialog information (530) when the information (830) indicates the predetermined style information (512,522) should be applied to the dialog information (530). Also, the method includes applying one style information of the plurality of style information (512,522) to the text information (534), using the reference style information (532) indicating one style information which is to be applied to the text information (534) among the plurality of style information (512,522), and applying the partial style information (536) to a portion of the text information (534) when the information (830) does not indicate predetermined style information (512,522) should be applied to the dialog information (530). Accordingly, an output style of the subtitle data can be changed in a variety of ways. Also, the special style can be applied in order to emphasize a portion of the subtitles.
Patent EP-1975805-A2 (EP)
Inventor: MCCARTHY STEVEN J
IPC: H04L29/08
Filed: 2004-02-25
Abstract: A communications system may include an application server and at least one communications device for processing requests from one another. The communications device may process requests using an HTTP client application, for example. Furthermore, the system may also include an HTTP server for interfacing the HTTP client application with the application server. The HTTP server and the HTTP client application may format requests to be communicated therebetween via the Internet in an HTTP format, and each may provide additional state information with the HTTP formatted requests recognizable by the other for authenticating the application server and the HTTP client application to one another. Furthermore, the HTTP client application may request a first universal resource locator (URL) from the HTTP server for accepting work requests from the application server, and a second URL different from the first URL for responding to work requests from the application server.
Patent EP-2056097-A2 (EP)
Inventor: TOYODA YOSHIHIRO
IPC: G01N21/956
Filed: 2008-10-17
Abstract: A producing method of a wired circuit board includes the steps of preparing an insulating base layer, forming a wire on the insulating base layer, forming an insulating cover layer on the insulating base layer so as to cover the wire, and applying near-infrared light with a wavelength of more than 700 nm and less than 950 nm from either one of the insulating base layer and the insulating cover layer through the other insulating layer to thereby inspect a foreign substance with the light transmitted therethrough.
Patent EP-2072723-A2 (EP)
Inventor: AXMANN HORST
IPC: E05C9/04
Filed: 2008-10-27
Abstract: The closure has a latch (27) and an auxiliary latch synchronously locked by key actuation. A latch bolt and an auxiliary latch bolt are synchronously retracted by pusher latch or change actuation. A slider is drive-connected with a driving bar (26') in a main lock. A rotating arm (7) designed as double arm lever and works on the slider, where the slider is attached to the rotating arm and the latch bolt by gears (23). A stop (38) at the slider or the rotating arm permits a movement of the slider in an inference direction by the rotating arm.
Patent EP-1967693-A2 (EP)
Inventor: ANDERSON DEREK W
IPC: F01D5/00
Filed: 2008-03-05
Abstract: A defect in a splitter fairing (26) of a turbine engine (10) is repaired by removing a forward portion (30) of the splitter fairing (26) and salvaging the remaining original portion (54) of the splitter fairing (26). The forward portion (30) includes an inner flange (46) and outer surface that create a channel. A replacement ring (56) is provided and welded to the original portion (54). The replacement ring (56) has minimum dimensions equal to the maximum height and width of the removed forward portion (30). Material from the replacement ring (56) is then removed to obtain a profile with essentially the same profile for the inner flange, outer surface, and channel as the original dimensions of the splitter fairing (26) before the defect occurred.
Patent EP-2027845-A2 (EP)
Inventor: HORNBACH DAVID W
IPC: A61G7/018
Filed: 2008-08-20
Abstract: A patient support apparatus comprises a lower frame (14), a lift mechanism (16), a drive mechanism (38), and an upper frame (12). The lower frame (14) includes a lift drive configured to at least one of expand and contract the lift mechanism (16). The lift mechanism (16) is pivotably coupled with the lower frame (14) to rotate about a rotational axis (R1). A drive mechanism (38) is coupled between the lift mechanism and the lower frame. The drive mechanism (38) is configured to rotate the lift mechanism (16) about the rotational axis (R1). The upper frame (12) is supported on the lift mechanism (16) and responsive to the rotation of the lift mechanism (16) to rotate a patient about the rotational axis (R1).
Patent EP-2125684-A2 (EP)
Title: Dérivés de colchicine, leur procédé de préparation et utilisations apparentées dans le domaine médical
Inventor: FRINGUELLI FRANCESCO
IPC: C07C323/22
Filed: 2008-02-18
Abstract: La présente invention porte sur des composés dérivés de la colchicine, sur leur procédé de préparation et sur leurs utilisations dans le domaine médical. En particulier, l'invention concerne la synthèse de conjugués et dérivés de colchicine avec une molécule support visant au traitement antifibrotique de maladies hépatiques chroniques.
Patent EP-2163078-A2 (EP)
Title: Dispositif de poche en tandem synergétique
Inventor: RAINES MOSHE
IPC: H04M1/7246
Filed: 2008-06-04
Abstract: L'invention concerne un dispositif de vidéophone comprenant deux unités constitutives 30, 34. Lorsqu'elles sont découplées l'une de l'autre, la première unité est un téléphone mobile 34 (par exemple, un téléphone cellulaire ou un téléphone de voix sur IP) qui offre des services de téléphonie vocale, et la seconde unité 30 est un dispositif de lecture vidéo (par exemple, un lecteur MP4) qui offre des services de lecture multimédia. Lorsqu'elles sont couplées l'une à l'autre pour former un « dispositif en tandem » 32, le dispositif en tandem 32 est fonctionnel pour offrir des services de visiophonie en utilisant un CODEC embarqué 224 du dispositif de lecture multimédia, un écran 250 du dispositif de lecture multimédia, et un émetteur récepteur RF 130 du téléphone mobile. Diverses caractéristiques de conditionnement sont décrites. L'invention concerne aussi un dispositif en tandem comprenant un dispositif GPS sans écran 330 et un téléphone mobile.
Patent EP-2162119-A2 (EP)
Title: Formulation pharmaceutique stable pour un inhibiteur de dpp-iv
Inventor: WU ZHEN-PING
IPC: A61K31/4025
Filed: 2008-05-21
Abstract: L'invention concerne une forme de dosage pour un inhibiteur de DPP-IV antidiabétique de formule (I) sous forme de son sel de tartrate, la pureté de l'ingrédient pharmaceutique actif y étant maintenue pendant une période de stockage prolongée dans des conditions similaires à celles généralement rencontrées dans un stockage domestique de la médication par un patient diabétique. Une formulation exempte de sels de calcium tels que le phosphate de calcium, mais comprenant la cellulose microcristalline, la copovidone, la crospovidone, le dioxyde de silicium colloïdal et le stéarate de magnésium, lorsqu'elle est compactée en un comprimé avec l'ingrédient pharmaceutique actif, s'est avérée être stable pendant au moins six mois à 40°C et à une humidité relative de 75%. L'invention concerne également des procédés de préparation de la forme pharmaceutique.
Patent EP-2170918-A2 (EP)
Title: Dérivés de nucléoside-5'-<i>o</i>-hypophosphates et leurs analogues mono- et dithiohypophosphates et leur procédé de fabrication
Inventor: STEC WOJCIECH J
IPC: C07H19/04
Filed: 2008-07-01
Abstract: La présente invention concerne des dérivés de nucleosides 5'-O-hypophosphates et leurs analogues mono- and dithiohypophosphate, en particulier les nucleosides 5'-O-[β,β-dialkyl-(α- thiohypophosphate)]-, 5'-O-[β,β-dialkyl-(α,α-dithiohypophosphate)]-, 5'-O-[β,β-dialkyl-(α,β- dithiohypophosphate)-, 5'-O-[β-alkyl-(α-thiohypophosphate)]-, 5'-O-[β-alkyl-(α,oc- dithiohypophosphate)]-, 5'-O-(α-thiohypophosphate)]- et 5'-O-(a,a- dithiohypophosphate) de formule générale 1, dans laquelle A1 est un atome de fluor, un groupe azide ou hydroxyle, A2 est un atome d'hydrogène, B1 est de l'adénine, de la 2-chloroadénine, de la 2-bromoadénine, de la 2-fluoroadénine, de la 2-iodoadénine, de l'hypoxantine, de la guanine, de la cytosine, de la 5-fluorocytosine, de la 5- bromocytosine, de la 5-iodocytosine, de la 5-chlorocytosine, de l'azacytosine, de la thymine, du 5-fluorouracile, du 5- bromouracile, du 5-iodouracile, du 5-chlorouracile, du 5-(2-bromovinyl)uracile, un résidu 2-pyrimidione , W1 est un atome d'oxygène ou de carbone ou un groupe methylidène, W2 est un atome de carbone ou A1, A2, W2 représentent conjointement un atome de soufre ou un atome d'oxygène, Z1 est un atome d'hydrogène ou de fluor ou un groupe hydroxyle ou un groupe alcoxyle, Z2 est un atome d'hydrogène ou de fluor ou un groupe hydroxyle ou méthyle ou Z1 et Z2 représentent conjointement un groupe fluorométhylène ou A1, A2, Z1 et Z2 représentent conjointement une double liaison carbone-carbone, X1, X2 et Y représentent un atome d'oxygène ou un atome de soufre, R1 et R2 représentent un groupe alkyle ou un aryle simple ou un atome d'hydrogène, et leur procédé de fabrication.
Patent EP-2167518-A2 (EP)
Inventor: LANSALOT-MATRAS CLEMENT
IPC: C07F15/04
Filed: 2008-07-16
Abstract: The present invention discloses metallic complexes based on hydroxylcarbonyl fulvene ligands, their method of preparation and their use in the oligomerisation or polymerisation of ethylene and alpha-olefins.
Patent EP-2187985-A2 (EP)
Title: Échafaudages
Inventor: LANGFORD KELLY
IPC: A61L27/38
Filed: 2008-08-14
Abstract: L'invention porte sur des procédés de préparation d'implants tissulaires pour une utilisation dans l'augmentation, la réparation et la régénération de tissus.
Patent EP-2120842-A2 (EP)
Title: Systèmes hybrides organiques/inorganiques, comprenant des systèmes hybrides de phosphate de calcium fonctionnalisé, et un procédé de production à l'état solide de tels systèmes
Inventor: KARLINSEY ROBERT L
IPC: A61K6/884
Filed: 2008-01-23
Abstract: La présente invention concerne un procédé de production à l'état solide de fractions fonctionnalisées, comprenant le placement de quantités prédéterminées de matières organiques et inorganiques et un milieu de broyage dans une cuve reliée en rotation à une plate-forme tournante, d'une quantité de matière organique dans la cuve, la rotation de la cuve dans une première direction en faisant tourner la plate-forme tournante dans une seconde direction opposée à la première direction, le broyage des matières organiques et inorganiques en de plus petites particules organiques et inorganiques respectives, et la fusion de portions de particules organiques et de particules inorganiques pour définir des fraction fonctionnalisées. La matière inorganique peut inclure des phosphates de calcium de phase, de structure, et de composition variées. La matière organique peut inclure des tensioactifs anioniques, des tensioactifs cationiques, des tensioactifs neutres, des acides carboxyliques, des polymères, des copolymères, des copolymères blocs, et leurs combinaisons.
Patent EP-2197765-A2 (EP)
Inventor: ARNDT RAINER
IPC: A45C13/30
Filed: 2008-09-24
Abstract: A self-contained carrying strap (5) for an object rests closely against said object since the length of the strap corresponds to the periphery of the object. As the length of the carrying strap (5) can be modified only once at least in some sections, it can be stretched without resuming the original length thereof after stretching. In this form, the carrying strap (5) is a stable shoulder strap. The carrying strap (5) is not elastic. The stretching step triggers an irreversible process, by which the carrying strap (5) in the stretched state achieves a certain level of stability and rigidity. This process cannot be repeated.
Patent EP-2212717-A2 (EP)
Inventor: HANSEN RENE SKOV
IPC: G01S17/95
Filed: 2008-10-08
Abstract: The present invention relates to a compact, reliable and low-cost coherent LIDAR (Light Detection And Ranging) system for remote wind-speed determination, determination of particle concentration, and/or temperature based on an all semiconductor light source and related methods. The present invention provides a coherent LIDAR system comprising a semiconductor laser for emission of a measurement beam of electromagnetic radiation directed towards a measurement volume for illumination of particles in the measurement volume, a reference beam generator for generation of a reference beam, a detector for generation of a detector signal by mixing of the reference beam with light emitted from the particles in the measurement volume illuminated by the measurement beam, and a signal processor for generating a velocity signal corresponding to the velocity of the particles based on the detector signal.