baber/WOPTO huggingface dataset:
Patent CA-2886024-A1 (CA)
Inventor: YUHAS EDWARD RICHARD
IPC: A61K9/12
Filed: 2012-10-11
Abstract: A topical composition is provided in the form of a serum, lotion, cream, salve or gel, for use in the treatment of psoriasis in a patient. The composition comprises: (a) about 75 wt% to about 99 wt% of a C10-C30 carboxylic acid cholesterol/lanosterol ester mixture, based upon the weight of the composition less any solvent that may be present with a boiling point of 150°C or less. The composition also comprises (b) about 0.1 wt% to about 15 wt% of a penetration enhancer selected from the group consisting of oleyl alcohol, lauryl alcohol, isopropyl myristate, oleyl oleate, levulinic acid, glycerol monooleate, methyl laurate, sorbitan monooleate, triacetin, cetyl alcohol, cetyl lactate, dimethyl isosorbide, dipropylene glycol, ethyl hexyl lactate, glycolic acid, lauramine oxide, lauryl betaine, lauryl lactate, lauryl laurate, isopropyl pamitate, myristyl alcohol, myristal lactate, octyl salicylate, oleamine oxide, oleic acid, oleyl betaine, salicylic acid, stearyl alcohol, stearyl lactate, triethanolamine triacetate and combinations thereof. The composition further comprises (c) about 0.1 wt% to about 10 wt% of a water-insoluble film-forming/polymeric agent selected from the group consisting of polyalkenes, oleophilic copolymers of vinylpyrrolidone, acrylic copolymers, polyethylene glycol derivatives, polyolefins, polyurethanes and mixtures thereof. About 0 wt% to about 10 wt%  of an antioxidant (d) are provided in the composition, along with (e) about 0 wt% to about 10 wt% of a preservative selected from the group consisting of propyl paraben, methyl paraben, benzyl alcohol, benzalkonium chloride, tribasic calcium phosphate and phenoxyethanol or acids, and (f) about 0 to about 25 wt% of a vitamin. The treatment regimen consists of a topical administration of the composition to a psoriatic area of the patient at least once a day.
Patent CA-2886046-A1 (CA)
Inventor: MEDOFF MARSHALL
IPC: G01T7/08
Filed: 2014-03-07
Abstract: Materials, such as biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. Conveying systems, such as flowing gas conveying systems and such as closed-loop flowing gas conveying systems are described. Many potential lignocellulosic feedstocks are available today, including agricultural residues, woody biomass, municipal waste, oilseeds/cakes and seaweed, to name a few.
Patent CA-2886102-A1 (CA)
Title: Extrusion press systems and methods
Inventor: STEWART CHARLES L
IPC: B21C23/08
Filed: 2013-10-11
Abstract: Systems, devices, and methods are described for extruding materials. In certain embodiments, one or more hollow billets are loaded onto an elongate mandrel bar and transported along the mandrel bar to a rotating die. The billets are transported through fluid clamps, which engage the mandrel bar and provide cooling fluid to the mandrel bar tip, and through mandrel grips, which engage the mandrel bar and prevent the mandrel bar from rotating. One or more press-rams advance the billets through a centering insert and into the rotating die. A quench assembly is provided at an extrusion end of the extrusion press to quench the extruded material. A programmable logic controller may be provided to control, at least in part, operations of the extrusion press system.
Patent CA-2886529-A1 (CA)
Title: Funnel for facilitating emptying of a liquid-filled container
Inventor: SIMPSON DAVID
IPC: B67C9/00
Filed: 2015-03-30
Abstract: A funnel for facilitating emptying of a liquid-filled container includes a receptacle. The receptacle is configured to support the liquid-filled container in a declined position with an opening of the container at or near a lowermost point of the container. The receptacle has an outlet for liquid. The funnel also includes a container shelf, adjacent to the receptacle, configured to support the liquid-filled container in an inclined position in which the container is inclined towards the receptacle. A tipping edge between the receptacle and a top of the container shelf is adapted to act as a fulcrum for tipping the container from the inclined position to the declined position. The receptacle may be formed within an insert that is removable from a base section of the funnel. A piercing element for piercing a protective seal on the opening may protrude inwardly into the receptacle on an angle.
Patent CA-2887455-A1 (CA)
Inventor: CORRIA OSORIO ANGEL DE JESUS
IPC: A61P31/00
Filed: 2013-10-30
Abstract: The invention relates to branches of biotechnology and, in particular, to mutated polypeptides of the TGFß molecule, the primary sequence of which is highly homologous with the sequence of human TGFß. These muteins lose their ability to interact with ALK5 but retain their ability to interact with the rest of the receptors that form part of the receptor complex (TßRII and TßRIII). In addition, they can antagonise the signalling of all of the natural variants of the TGFß ligands, dependent on the recruitment of ALK5 in the receptor complex, and they have an immunomodulatory effect. The invention also relates to pharmaceutical compositions comprising, as active principle, the disclosed polypeptides or fusion proteins and to the therapeutic use of the disclosed polypeptides, fusion proteins and pharmaceutical compositions owing to their immunomodulatory effect on diseases such as cancer, diseases associated with fibrosis and chronic infectious diseases.
Patent CA-2889297-A1 (CA)
Inventor: GOMES ALBERTO REGIO
IPC: F25D16/00
Filed: 2015-04-24
Abstract: The present application provides a refrigerated display case. The refrigerated display case may include a refrigeration component, an air plenum in communication with the refrigeration component, a shelf in communication with the air plenum, a phase change material tank positioned about the shelf, and a phase change material positioned within the phase change material tank such that a substantially uniform temperature is maintain across the shelf.
Patent CA-2890462-A1 (CA)
Inventor: BAKALE ROGER P
IPC: C07D235/16
Filed: 2013-11-12
Abstract: The present invention is directed to bendamustine esters and bendamustine amides and their use for the treatment of cancer: (I) wherein R1 is C6-C24alkyl or polyethylene glycol; and (II) wherein R2 is C1-C24alkylene; and R3 is-COOC1-3alkyl; or R2-R3 is C1-C24alkyl; or a pharmaceutically acceptable salt form thereof.
Patent CA-2891066-A1 (CA)
Inventor: BANERJEE KASHI
IPC: C02F1/52
Filed: 2013-11-25
Abstract: A method for removing sulfate from a wastewater stream includes mixing gibbsite and a calcium source to precipitate Ettringite from the wastewater stream and produce an effluent with a reduced sulfate concentration. The gibbsite in the precipitated Ettringite is regenerated by mixing an acid with the Ettringite and precipitating gibbsite particles, after which the gibbsite particles are subjected to a crystallization process to increase the size of the gibbsite particles which are recycled back to the main stream.
Patent CA-2891433-A1 (CA)
Title: Attachment for a syringe or carpule
Inventor: HUND PETRA
IPC: A61M5/24
Filed: 2013-11-12
Abstract: The invention relates to an attachment for a syringe, carpule, or the like, which includes a distal end having a terminal extension. The extension has an miter surface, a free end, and at least one depression introduced at a spacing thereto into the outer surface. The attachment includes an annular base body, placeable onto the extension, wherein the base body encloses a free space into which the extension is introducible. The base body contains two materials, preferably is comprised thereof, of which a first material is dimensionally stable and a second material is softer than first material and deformable.  The base body has at least one engagement region, which in the plugged-onto-the-extension state engages into the at least one depression, wherein the base body has, along an imaginary circumferential line, at least one first region with the first material and at least one second region containing the second material.
Patent CA-2891517-A1 (CA)
Inventor: ULRICH JAMES F
IPC: B23K9/10
Filed: 2014-02-20
Abstract: L'invention concerne un système de soudage hybride. Dans un mode de réalisation, le système de soudage comprend un générateur entraîné par moteur, un dispositif de stockage d'énergie, un contacteur et un dispositif de commande. Le dispositif de commande peut être conçu pour réguler la sortie de puissance de soudage provenant du générateur lorsqu'une sortie commandée est inférieure à un niveau de seuil ; et provenant du générateur et du stockage d'énergie lorsque la sortie commandée est supérieure au seuil. La fermeture du contacteur permet au dispositif de stockage d'énergie de contribuer à la puissance de soudage pendant les opérations de soudage et d'être chargé par la sortie de générateur indépendante de la charge entre les opérations de soudage. L'invention concerne également des systèmes et des procédés de soudage hybride.
Patent CA-2892403-A1 (CA)
Title: Client-side advertising decisions
Inventor: CHIA TECK
IPC: G06Q30/02
Filed: 2013-12-12
Abstract: In one embodiment, a method includes a client computing device receiving one or more advertisements for presentation to a user associated with the client computing device. The client computing device selects from among the received advertisements for presentation to the user based on Information stored locally on the client computing device and associated with a value of the advertisements with respect to the user. The client computing device then presents to the user one or more of the selected advertisements to the user.
Patent CA-2894781-A1 (CA)
Inventor: BASTIN PIERRE
IPC: C09D125/04
Filed: 2013-12-20
Abstract: The invention provides a PVC-free surface covering comprising at least one layer of a thermoplastic composition, said composition comprising: - a polymer matrix comprising : (a) at least one ionomer and/or at least one acid copolymer; and (b) at least one styrenic thermoplastic polymer; and - at least one filler.
Patent CA-2895754-A1 (CA)
Inventor: LAFONTAINE SERGE R
IPC: H02J7/02
Filed: 2013-12-16
Abstract: A method of detecting whether a receiver coil is near a transmit coil in a wireless power transfer system (WPTS), the method involving: applying a pseudo-random signal to the transmit coil; while the pseudo-random signal is being applied to the transmit coil, recording one or more signals produced within the WPTS in response to the applied pseudo-random signal; by using the one or more recorded signals, generating a dynamic system model for some aspect of the WPTS; and using the generated dynamic system model in combination with stored training data to determine whether an object having characteristics distinguishing the object as a receiver coil is near the transmit coil.
Patent CA-2897138-A1 (CA)
Title: Muffler
Inventor: KAINUMA KATSUHIKO
IPC: F01N13/08
Filed: 2013-12-18
Abstract: A muffler comprises a double pipe section formed by inserting an end of a first pipe-like member (10) into a second pipe-like member (20) from an end thereof. The front end section (23) of the second pipe-like member is joined to the outer peripheral surface of the first pipe-like member. The portion of the second pipe-like member which forms the double pipe section is provided with: a first portion (22) which is located close to the front end of the first pipe-like member; and a second portion (21) which is located close to the front end of the second pipe-like member and which has a greater diameter than the first portion. A resonance chamber (31) is formed between the first pipe-like member (10) and the second portion (21). A connection passage (32) which connects an exhaust gas flow passage and the resonance chamber is formed between the first pipe-like member (10) and the first portion (22). A Helmholtz resonance system is formed by the resonance chamber (31) and the connection passage (32).
Patent CA-2897710-A1 (CA)
Title: System and method for continuously removing a particular type of gas molecules from a gas stream
Inventor: WEST JONATHAN D
IPC: B01D53/02
Filed: 2015-07-20
Abstract: A method for continuously removing a particular type of gas molecules ("gas molecules") from a gas stream includes selecting a liquid having an affinity for the gas molecules to be removed, and providing the selected liquid to each of a first and second mat, each mat formed from a plurality of fibers having the ability to retain the selected liquid within longitudinally extending channels having longitudinally extending openings against moving into the space between the individual fibers, the mats in fluid communication therebetween with the selected liquid. The method includes directing the gas stream through a portion of the first mat into contact with the selected liquid along the longitudinally extending openings whereby the selected liquid absorbs the gas molecules, and directing a second gas through a portion of the second mat so that the gas molecules, absorbed by and disbursed throughout the selected liquid, are stripped and carried away.
Patent CA-2897821-A1 (CA)
Inventor: ADAMSKI-WERNER SARA L
IPC: A23L27/30
Filed: 2014-02-19
Abstract: The present invention includes compounds having structural formula (I), or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of enhancing the sweet taste of compositions.
Patent CA-2898615-A1 (CA)
Inventor: HOEKSTRA WILLIAM J
IPC: A61P29/00
Filed: 2014-01-27
Abstract: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
Patent CA-2902246-A1 (CA)
Inventor: BROUWER GERARDUS J
IPC: A01B45/04
Filed: 2014-02-24
Abstract: A system for disposing of a defective sod roll from a sod harvester is disclosed. The system includes: (i) a transport conveyor; (ii) an accumulator located behind the transport conveyor, such that a gap is defined between a rear end of the transport conveyor and a front end of the accumulator; and (iii) a movable tray located proximate to the gap. The tray moves between a retracted position and an extended position. When the tray is in the retracted position, the gap is open and a receiving surface of the tray is in a generally horizontal orientation. When the tray is in the extended position, the tray is located within the gap to receive the sod roll from the transport conveyor.
Patent CA-2903366-A1 (CA)
Title: Flexible temple for spectacles
Inventor: CABRE OZORES ALEJANDRO
IPC: G02C5/14
Filed: 2014-03-05
Abstract: The invention relates to a flexible temple for spectacles which separate at the bridge area (3), which consists of a narrow, elongate part, the ends of which are coupled to the frame (2), and which is closed at the rear of the head, and made up of a flexible structure with three specific, differentiated areas, at the ends and central portion, including: respective semi-rigid sections (11), which correspond to straight sections of the temple at the ends thereof, corresponding to the portion at the temples of the wearer; and a flexible central area (12), corresponding to the remainder that surrounds the head at the rear, with a higher degree of flexibility than that of the semi-rigid sections (11) which allows the temple (1) to be bent until the spectacles can be inserted in a case such as not to project from the space taken up by the frame (2). The semi-rigid sections (11) are made of polymer, and the flexible central area (12) is made of elastomer.
Patent CA-2903427-A1 (CA)
Inventor: OFEK EYAL
IPC: G06T19/20
Filed: 2014-03-06
Abstract: An augmented reality (AR) experience is mapped to various environments. A three-dimensional data model that describes a scene of an environment, and a description of the AR experience, are input. The AR experience description includes a set of digital content that is to be mapped into the scene, and a set of constraints that defines attributes of the digital content when it is mapped into the scene. The 3D data model is analyzed to detect affordances in the scene, where this analysis generates a list of detected affordances. The list of detected affordances and the set of constraints are used to solve for a mapping of the set of digital content into the scene that substantially satisfies the set of constraints. The AR experience is also mapped to changing environments.
Patent CA-2903698-A1 (CA)
Title: Souris exprimant un repertoire limite de chaines legeres d'immunoglobuline
Inventor: BABB ROBERT
IPC: C07K16/00
Filed: 2014-03-13
Abstract: L'invention concerne une souris génétiquement modifiée, la souris exprimant un répertoire de chaînes légères d'immunoglobuline caractérisé par un nombre limité de domaines variables de chaîne légère. L'invention concerne des souris qui présentent un choix de deux segments de gènes variables de chaîne légère humaine de telle sorte que les chaînes légères d'immunoglobuline exprimées par la souris comprennent l'un des deux segments de gènes variables de chaîne légère humaine. L'invention concerne des procédés de fabrication d'anticorps bispécifiques ayant des chaînes légères universelles à l'aide des souris telles que décrites ici, comprenant des régions variables de chaîne légère humaine. L'invention concerne des procédés de fabrication de régions variables humaines appropriées pour l'utilisation dans des protéines de liaison multi-spécifiques, par exemple, des anticorps bispécifiques et des cellules hôtes.
Patent CA-2904339-A1 (CA)
Inventor: CHEN LIN
IPC: A61K31/167
Filed: 2014-03-06
Abstract: The present disclosure provides novel compounds capable of functioning as transcription factor modulators, as well as compositions, pharmaceutical formulations, and kits. Also provided are methods of treating a condition regulatable by a transcription factor and/or cofactor using the compounds, compositions, pharmaceutical formulations, and kits provided herein. Alterations of epigenetic regulation are a characteristic of many diseases. The myocyte enhancer factor 2 (MEF2) transcription factor plays central roles in the transmission of extracellular signals to the genome and in the activation of the genetic programs that control cell differentiation, proliferation, morphogenesis, survival and apoptosis of a wide range of cell types (Potthoff et al., 2007).
Patent CA-2904408-A1 (CA)
Inventor: CHITTOOR JAISHREE M
IPC: C07H21/04
Filed: 2014-03-11
Abstract: The invention provides recombinant DNA molecules and constructs, as well as their nucleotide sequences, useful for modulating gene expression in plants. The invention also provides transgenic plants, plant cells, plant parts, and seeds comprising a recombinant DNA molecule comprising a DNA molecule operably linked to heterologous transcribable DNA molecule, as are methods of their use.
Patent CA-2906435-A1 (CA)
Inventor: MURATA ATSUSHI
IPC: B03B5/28
Filed: 2014-03-19
Abstract: This hydrocarbon synthesis apparatus is provided with: a reactor for bringing a syngas which comprises carbon monoxide gas and hydrogen gas as main components into contact with a slurry obtained by suspending a solid catalyst in a liquid hydrocarbon compound, and thus synthesizing liquid hydrocarbon compounds by a Fischer-Tropsch process; a filter which is provided in the reactor and which separates the liquid hydrocarbon compounds from the catalyst; and a pulverized catalyst particles discharging means for discharging pulverized catalyst particles to the outside of the reactor, said pulverized catalyst particles being formed by pulverization of the solid catalyst contained in the slurry.
Patent CA-2911125-A1 (CA)
Inventor: WILLIAMS JUSTIN
IPC: A61B17/115
Filed: 2015-11-03
Abstract: A loading unit and retention band assembly including a shell and a retention band.  The shell has a proximal end portion that defines an engagement window and that includes an annular surface. The retention band is disposed radially about the annular surface of the proximal end portion and includes a resilient body having first and second ends. The first end includes a resilient lock that is configured to extend through the engagement window of the proximal end portion of the shell. The resilient lock is dimensioned to releasably engage a surgical instrument.
Patent CA-2912302-A1 (CA)
Title: Compositions and methods for treating cardiometabolic diseases and disorders
Inventor: SALEH TAREK M
IPC: A61K31/4745
Filed: 2013-05-14
Abstract: Described herein are combinations useful for treating or preventing a cardiometabolic disease or disorder, or which can be used for appetite suppression, for improvement of endothelial function, for controlling weight, or a combination of one or more thereof. The combinations comprise Berberine, alpha lipoic acid (LA), and apocynin, or an isomer, derivative, pharmaceutically acceptable salt or ester of one or more thereof. Methods of treatment using the combinations, as well as compositions and related medical uses are also described.
Patent CA-2912491-A1 (CA)
Inventor: JONES TILFORD C
IPC: A63B69/38
Filed: 2015-11-18
Abstract: Provided is an adjustable backboard having a mount that allows a user to adjust an angle of the backboard relative to the ground and a method of using the backboard to hit tennis balls. The backboard is constructed and sized to rebound tennis balls.
Patent CA-2914108-A1 (CA)
Inventor: KWON YOUNGHOON
IPC: H04W74/04
Filed: 2013-06-13
Abstract: A method for exchanging data includes generating a usage indicator for an access window, the usage indicator including a first indication of if an allowed station in a list of allowed stations needs to receive information about its resource allocation and at least one of a second indication of a start time of the access window, and a third indication of the list of allowed stations, and broadcasting the usage indicator. The method also includes exchanging data with at least one of the allowed stations within the access window in accordance with the usage indicator.
Patent CA-2914288-A1 (CA)
Inventor: MILES PHILIP
IPC: G01V3/165
Filed: 2015-12-10
Abstract: A composite electromagnetic (EM) system and method for measuring naturally occurring magnetic fields and controlled magnetic fields. The composite EM system includes a housing (1102), an audio-magnetotelluric (AMT) system (1104) attached to the housing and measuring natural magnetic fields generated by earth, a frequency-domain EM (FDEM) system (1140) attached to the housing and measuring controlled magnetic fields generated by a controlled source, and a position and orientation (POS) system (1120) attached to the housing and configured to calculate an orientation and a position of the AMT system and housing relative to the earth. The housing is configured to be attached to an aircraft for being airborne while measuring the natural magnetic fields and the controlled magnetic fields.
Patent CA-2917742-A1 (CA)
Inventor: AGARWAL VEENA
IPC: A61P35/00
Filed: 2014-07-11
Abstract: The present invention relates to a pharmaceutical combination comprising a cyclin dependent kinase (CDK) inhibitor represented by a compound of formula I (as described herein) or a pharmaceutically acceptable salt thereof; and at least one anticancer agent selected from a BRAF inhibitor or a MEK inhibitor, for use in the treatment of melanoma. The present invention also relates to a method for the treatment of melanoma comprising administering to a subject in need thereof, a therapeutically effective amount of a CDK inhibitor and a therapeutically effective amount of at least one anticancer agent selected from a BRAF inhibitor or a MEK inhibitor.