baber/WOPTO huggingface dataset:
Patent FI-83649-B (FI)
Inventor: BRAENDSTROEM ARNE ELOF
IPC: A61K31/415
Filed: 1984-03-02
Granted: 1991-04-30
Abstract: Novel salts of omeprazole with Li<sup>+</sup>, Na<sup>+</sup>, K<sup>+</sup>, Mg<sup>2+</sup>, Ca2+, Ti<sup>4+</sup>, N<sup>+</sup>(R<sup>1</sup>)<sub>4</sub>as cation; processes for their preparation thereof, pharmaceutical compositions containing such salts and their use in medicine.
Patent FI-80526-B (FI)
Inventor: SAVISALO HANNU
IPC: G01N27/416
Filed: 1986-09-08
Granted: 1990-02-28
Abstract: The invention concerns a procedure for controlling cellulose digestion by measuring the activity of chemicals exerting essential influence on cellulose digestion which are present in the cellulose digester, the feeding of chemicals to be added into the cellulose digester being controlled on the basis of the result of measurement. The measurement is carried out by placing in the cellulose digester one or several measuring electrodes (12) and reference electrodes (13) and a current-supplying counterelectrode (14), to the circuit thus established being supplied current from a current source (15) in such manner that the voltage across the measuring electrode (12) and the reference electrode (13), in other words the electrochemical potential of the measuring electrode (12), is substantially constant, whereby the current intensity corresponding to said potential is directly proportional to the activity of said chemicals.
Patent FI-88502-B (FI)
Inventor: BINDER DIETER
IPC: A61P9/00
Filed: 1987-03-20
Granted: 1993-02-15
Abstract: Therapeutically useful 1-[3-(2-dialkylaminoethoxy)-2-thienyl]-3-phenyl-1-propanones of the formula    <IMAGE>  (I)  and acid addition salts thereof, wherein R and R1 each are hydrogen or methyl, R2 and R3, which are the same or different, each are alkyl, cycloalkyl, alkenyl or alkynyl each containing up to 8 carbon atoms, or R2 and R3 together with the nitrogen atom to which they are attached form a 5 to 7-membered saturated ring or a saturated heterocyclic ring which may contain optionally an oxygen or nitrogen atom as further hetero atom in the ring, a further nitrogen atom being unsubstituted or substituted by an alkyl radical containing 1 to 3 carbon atoms. The compounds are useful for the treatment of various disturbances of the heart rhythm.
Patent FI-83499-B (FI)
Inventor: BOEGH BO BOJESEN
IPC: B65B11/02
Filed: 1987-12-17
Granted: 1991-04-15
Abstract: A method and an apparatus for packaging a number of substantially cylindrical packages (2) consisting of a within certain limits elastic insulation material, for instance mineral wool, said packages having open ends, but being at their side faces surrounded by a substantially airtight foil layer, by which method the open ends of the packages are temporarily closed in an essentially airtight way, the volume encased by the foil layer and the temporary sealings being connected to a vacuum source to reduce the volume of the packages, the packages (2) thus reduced being enclosed in a tight enclosure before the vacuum is disconnected. To use the compression by means of vacuum not only for reducing the volume of the individual packages but also for eliminating the interspaces between cylindrical packages put together, the method comprises the steps that a number of packages (2) are placed close to one another resting on one of the end faces in a rectangular or in particular cases a quadratic pattern, the airtight sleeves touching one another, on an approximately plane surface (1), the outline of which corresponds substantially to the volume of the closely packed packages, and in that the packages are being closed from above with a plate (4) parallel therewith, at least one of the plates (1,4) being perforated at the end surfaces of the packages and the packages (2) being pressed closely against each other in the area close to the plates (1,4) by means of holding means (10,11); and that the enclosure around the packages is provided by wrapping the packages in a foil after having removed the holding means and before disconnecting the vacuum.
Patent FI-90780-B (FI)
Inventor: RINK HANS
IPC: C08F8/30
Filed: 1988-03-28
Granted: 1993-12-15
Abstract: A synthetic resin based on a polystyrene that can be used as a support for solid phase peptide synthesis and that has been cross-linked with from 0 to 5 mol % of divinyl benzene, characterized in that it has been substituted at benzene rings of its skeletal structure by groups of the formula    <IMAGE>  (I)  in which X represents -O- or -NH- and R represents C1-C4-alkyl, as a support renders possible the solid phase synthesis of peptides and peptide amides that are, if desired, protected at the N-terminal and/or at other functional groups. The resin is manufactured by reaction of a customary chloromethylated polystyrene resin with an alkali metal salt of the corresponding 4-hydroxybenzophenone and subsequent reduction of the carbonyl group and, optionally, amination.
Patent FI-93648-B (FI)
Inventor: HERT MARIUS
IPC: C09D123/00
Filed: 1988-10-13
Granted: 1995-01-31
Abstract: Polymers with a melt index of between 1 and 20 dg/min, containing units (A) derived from ethylene, units (B) derived from an anhydride of an ethylenically unsaturated  alpha , beta -dicarboxylic acid and, if appropriate, units (C) derived from an alkyl acrylate or methacrylate whose alkyl group contains from 1 to 12 carbon atoms, characterised in that, per 100 moles, they contain: from 83 to 99.7 moles of units (A), from 0.29 to 3 moles of units (B), from 0 to 13.6 moles of units (C) and additionally from 0.01 to 0.4 moles of units (D) derived from at least one polyol poly(meth)acrylate. The process for their preparation consists in copolymerising a mixture of ethylene, of anhydride of an ethylenically unsaturated alpha , beta -dicarboxylic acid, of at least one polyol poly(meth)acrylate and, if appropriate, of at least one alkyl (meth)acrylate, at a temperature of between 140 and 280 DEG C, at a pressure of between 1000 and 2500 bars, in the presence of at least one free-radical initiator, and is characterised in that, before the copolymerisation, the polyol poly(meth)acrylate is dissolved in a solvent.
Patent FI-91860-B (FI)
Inventor: KLAUS MICHAEL
IPC: C07D/
Filed: 1989-02-22
Granted: 1994-05-13
Abstract: The novel compounds of the general formula 
<IMAGE>
 in which R<1> and R<2> independently of one another represent lower alkyl; or, taken together, represent alkylene having 3-5 C atoms in a straight chain; one of the radicals R<3> and R<4> denotes hydrogen and the other denotes hydrogen or lower alkyl; R<6> and R<7> denotes hydrogen or lower alkyl; R<5> and R<8> denote hydrogen, lower alkyl, lower alkoxy or halogen, X denotes -O-, -S-, -SO-, -SO2- or -NR<9>; R<9> denotes hydrogen, lower alkyl or acyl; Y denotes -S(O)mR<1><0> or -NHet, and, if X is - NR<9>-, -S-, -SO- or -SO2-, also denotes -N(R<1><1>)2 or -OR<1><2>; R<1><0> denotes lower alkyl; R<1><1> and R<1><2> denote hydrogen, lower alkyl or acyl; -NHet denotes a 5-8-membered, saturated or unsaturated monocyclic heterocycle bonded via an N atom; n denotes 2, 3 or 4 and m denotes 0, 1 or 2,
 can be used as active compounds for the treatment of diseases, for example neoplasias, dermatoses or presbyderma.
Patent FI-102387-B (FI)
Inventor: DAVEY CHERYL
IPC: C12Q1/6865
Filed: 1990-05-09
Granted: 1998-11-30
Abstract: The invention relates to a method for the synthesis of ribonucleic acid starting from deoxyribonucleic acid in which a target sequence is present. Said DNA is treated with restriction enzyme(s) followed by strand separation. Subsequently one uses one nucleic acid primer containing a promoter sequence coupled to a nucleotide sequence which corresponds to a part of the target sequence. The invention further relates to a test kit for synthesizing RNA.
Patent FI-102101-B (FI)
Inventor: RUDE EDWARD T
IPC: E05D11/10
Filed: 1992-07-10
Granted: 1998-10-15
Abstract: There is disclosed a hinge assembly that has a pintle and two plates that can rotate about the axis of the pintle. The first plate is irrotatably affixed to the pintle. The second plate is part of a friction element which also includes a band having a plurality of turns helically disposed about the pintle. Between the other end of the band and the second plate there is a spring that tightens the band about the pintle. The band is flexible enough so that it does not grip the pintle without the force of the spring. Frictional force is developed between the band and the pintle that opposes movement of the second plate in a direction that tends to tighten the band about the pintle. Movement of the second plate in the opposite direction tends to loosen the band's grip on the pintle so that very little frictional force is developed.
Patent FI-111871-B (FI)
Inventor: YOUNG CHAPMAN III
IPC: F42D1/10
Filed: 1993-02-03
Granted: 2003-09-30
Abstract: Hard compact materials, such as rock, concrete, et cetera, are broken by igniting an appropriately designed explosive or propellant charge placed within the hole or carried in a special charge-containing device with a short barrel which is inserted and sealed into a pre-drilled hole of particular geometry. One or more approximately cylindrical holes are drilled into the material to be broken by conventional drilling, such as used in the mining and construction industries. The holes have a relatively short depth to diameter ratio, being in the range of about 2:1 to 6:1, and preferably about 3:1 to 5:1. The holes are percussively drilled with microfractures in and around hole bottoms to provide fracture initiation sites at the hole bottoms so as to provide preferred fracture initiation roughly parallel to a free surface of material being excavated. The explosive or propellant charges may be any of several commercially available explosives or propellants, including standard military and commercial rifle powders and various recently developed liquid propellants. The propellant charges, whether solid or liquid, may be placed and ignited within a charge-containing device, which includes a short barrel inserted into the holes drilled into the material to be broken. The barrel of this device may be further sealed into the holes by a helical shim sealing method.
Patent FI-92920-B (FI)
Title: Method for the manufacture of moulded wood with hard surface
Inventor: KAUSE JAAKKO
IPC: B27M1/02
Filed: 1993-03-10
Granted: 1994-10-14
Abstract: The subject matter of the invention is a method for pressing wood to a predetermined shape by heating the piece of wood that is to be pressed prior to pressing. The piece of wood 6 that is to be pressed is heated by placing electrodes 13, 14 at the end thereof, an electrical current being passed through the piece of wood 6 by means of a current source 17 so that the piece of wood 6 is heated uniformly throughout before it is pressed to the required shape. <IMAGE>
Patent FI-111271-B (FI)
Inventor: NAKAMURA JUNJI
IPC: G01N33/574
Filed: 1995-08-01
Granted: 2003-06-30
Abstract: A method of examining hormone-dependent tumors which comprises culturing tumor tissues in each of (a) a medium, (b) a medium containing a hormone synthetase substrate, and (c) a medium containing both a hormone synthetase substrate and a hormone synthetase inhibitor, measuring the growth rate of tumor cells in each medium, determining (i) the ratio of the growth rate of tumor cells in the presence of a hormone synthetase substrate to that in a medium alone and (ii) the ratio of the growth rate of tumor cells in the presence of both a hormone synthetase substrate and a hormone synthetase inhibitor to that in a medium alone. This method enables judging whether there are any hormone synthetase and hormone-dependent growth of hormone-dependent tumors readily at the same time. Further it can be employed for developing a new method of classifying tumors and selecting a guide line for tumor therapy.
Patent HU-203757-B (HU)
Title: Process for producing antiviral terahydroimidazo(1,4)benzodiazepin-2-one derivatives and pharmaceutical compositionscontaining them as active components
Inventor: RAEYMAEKERS ALFONS HERMAN MARG
IPC: C07D487/06
Filed: 1989-03-16
Abstract: Novel antiviral tetrahydroimidazo[1,4]benzodiazepin-2-ones of formula   <CHEM> a pharmaceutically acceptable acid addition salt or a stereochemically isomeric form thereof, wherein R<1> is hydrogen, C1-8alkyl, C3-6alkenyl, C3-6alkynyl, C1-6alkylcarbonyl, C3-6cycloalkyl, or substituted C1-6alkyl;  R<2> is hydrogen, C1-6alkyl or C3-6alkenyl  R<3> is hydrogen or C1-6alkyl; R<4> is hydrogen; substituted C1-6alkyl; C1-6alkylcarbonyl; C3-6alkenyl; C3-6cycloalkyl; C5-6cycloalkenyl;  R<5> is hydrogen, C1-6alkyl or halo; and  aryl is optionally substituted phenyl; pharmaceutical compositions containing these compounds as active ingredient; processes for preparing said compounds and compositions.
Patent HU-201720-B (HU)
Title: Process for improving particularly optical and mechanical properties of surface defects, and repair surface thereof, of multilayer screenglasses, mainly windscreens
Inventor: SOMFAI ANDRAS
IPC: C03C27/06
Filed: 1988-03-23
Abstract: Windscreens damaged by dents, are repaired by using fillers made of anti-ageing epoxy resins, followed by glass inserts glued into place.
Patent HU-213019-B (HU)
Title: Process for producing soluble forms of t-4 protein
Inventor: ARTHOS JAMES
IPC: C12Q1/70
Filed: 1989-02-24
Abstract: This invention provides a therapeutic agent capable of specifically forming a complex with human immunodeficiency virus envelope glycoprotein which comprises a polypeptide. In one embodiment of the invention, the amino acid sequence of the polypeptide comprises the amino acid sequence shown in Figure 6 from about + 3 to about + 185 fused to the amino acid sequence from about +351 to about +369. In another embodiment of the invention, the amino acid sequence of the polypeptide comprises the amino acid sequence shown in Figure 6 from about + 3 to about +106 fused to the amino acid sequence from about +351 to about +369. In yet a further embodiment of the invention, the amino acid sequence of the polypeptide comprises the amino acid sequence shown in Figure 6 from about + 3 to about +185. 
     This invention also provides a method for treating a subject infected with a human immunodeficiency virus. The method comprises administering to the subject an effective amount of a pharmaceutical composition comprising an effective amount of a therapeutic agent of the invention and a pharmaceutically acceptable carrier.
Patent HU-190676-B (HU)
Title: Herbicide compositions containing sulphonamide derivatives as active substances and process for preparing the active substance
Inventor: REAP JAMES J
IPC: C07D521/00
Filed: 1981-07-10
Abstract: A compound of the formula: <CHEM>  where  W is O or S;  Q is O or NR5; R1, R2, R3 and R4 are as defined in claim 1.  A is <CHEM> X is NH2, N(CH3)2, NHCH3, C1-C4 alkyl, C1-C4 alkyl substituted with 1-3 atoms of F, Cl or Br, CH2OCH3, CH2OCH2CH3, C1-C4 alkoxy,  C1-C2 alkylthio, C3-C4 alkenyloxy,  C3-C4 alkynyloxy, OCH2CH2OCH3 or  C2-C4 alkoxy substituted with 1-3 atoms of F, Cl or Br;  n is 1 or 2;  Y is H, CH3, OCH3 or Cl;  X1 is O or CH2;  Y1 is H, CH3, OCH3 or Cl;  X2 and Y2 are independently CH3 or OCH3; and  Z is CH, N, CCH3 CBr, CCl, CF, Cl, CC2H5, CCH2CH2Cl or CCH2CH=CH2; The compound may be formulated in compositions and may be used as general, as well as selective pre- and post emergence herbicides. The compounds may be prepared from novel intermediates of formula <CHEM> where Q, W, R1, R2 and R3 are as defined above, and Z min  is CH or N).
Patent HU-196421-B (HU)
Title: Process for the selective synthesis of amikacine
Inventor: MANGIA ALBERTO
IPC: C07H15/22
Filed: 1986-06-30
Abstract: A novel process for the synthesis of amikacin starting from kanamycin A protected at the positions 3 and 6' is described comprising the reaction of the latter with a salt of a bivalent metal cation selected among zinc, nickel, iron, cobalt, manganese, copper and cadmium in the presence of water as the solvent or co-solvent followed by the in situ reaction of the resulting complex with a reactive derivative of L-amino-2-hydroxybutyric acid, removal of the metal cation of the protecting groups and purification of the thus obtained raw product. the acylation under these conditions is extremely selective.
Patent HU-194529-B (HU)
Title: New process for producing 2-aroyl-phenylacetone-derivatives
Inventor: LANG TIBOR
IPC: C07C49/84
Filed: 1984-07-20
Abstract: The proposed method is to be used for the prepn. of family of 2-aroil-phenyl-acetone derivs. of type indicated by general formula (I), where R fixed or replaceable phenyl group. 1-3 replacements may be used, such as halogen atoms, hydroxyl, acetoxy-, C1-C4 alkyl, alkoxy-, nitro- or methylene dioxy- gps. R may also represent fixed or replaceable naphthyl gp., where replacements are hydroxyl or acetoxy gps. - R1 is H or 1-4C alkyl gp. R2 and R3 are 1-4C alkyl gps. or R2 and R3 together represent methylene gp.
Patent HU-188203-B (HU)
Inventor: LANG TIBOR
Filed: 1982-09-14
Abstract: A találmány tárgya eljárás 6-demetil-6-dezoxi-6metilén-5-hidroxi-tetraciklin (metaciklin) és sósavas sójának előállítására I la-klór-5-hidroxi-tetraciklin-6,12-hemiketálból vagy savaddíciós sójából, amelynek során a kiindulási vegyületből hidrogénfluorid vízelvonó szerrel 1 la-klór-6-demetil-6dezoxi-6-metilén-5-hidroxi-tetraciklint (klórmetaciklint) állítunk elő, majd ezt trifenil-foszfindehalogénező szerrel kezelve metaciklinné alakítjuk. Az eljárás abban áll, hogy a vízelvonással keletkező klórmetaciklin dehalogenezését elkülönítés nélkül, magában a hidrogérfluoridos oldatban vagy hidrogénfluoridot tartalmazó szerves oldószerben végezzük, majd a metaciklin hidrogénfluorid sót szintén elkülönítés nélkül sósavas sóvá alakítjuk. A találmány szerinti eljárással egyszerű, ipari megvalósításra alkalmas módon, magas hozammal, nagytisztaságú metaciklin sósavas sót állíthatunk elő, amely közvetlenül alkalmas gyógyászati felhasználásra, vagy előnyös kiindulási vegyület a-6-dezoxi-5-hidroxi-tetraciklir (doxiciklin) előállításához. -1-
Patent HU-210097-B (HU)
Inventor: PETZOLD HEINRICH
IPC: A23L7/152
Filed: 1990-06-11
Abstract: Die Erfindung betrifft ein Verfahren zur Herstellung eines Getreidekeimproduktes fuer Nahrungszwecke. Die Erfindung beschreibt ein Verfahren zur Herstellung von Getreidekeimprodukten, die vielseitig fuer Nahrungszwecke eingesetzt werden koennen. Die Aufgabe der Erfindung besteht darin, Verfahrensbedingungen zur Behandlung von Getreidekeimen aufzuzeigen, die ohne Verlust wesentlicher Inhaltsstoffe zu lange haltbaren Getreidekeimen fuehren. Sie wird in der Weise geloest, dasz Getreidekeime in einen Wirbelschichtspruehgranulator eingegeben werden und bei einer Produkttemperatur von max. 40 C auf einen Feuchteanteil von * % getrocknet werden, wobei gleichzeitig Feinanteile 1,5 mm aus dem Wirbelschichtgranulator ausgetragen werden. Anschlieszend werden Hydrokolloide und/oder Fette und/oder OEle und/oder pharmazeutische UEberzugsstoffe und gegebenenfalls Geschmacks- und/oder Aromastoffe zur Ummantelung aufgesprueht. Das Aufspruehen erfolgt derart, dasz entweder einer dieser Stoffe allein oder mehrere Stoffe einzeln nacheinander oder zwei oder mehrere Stoffe in Form einer stabilen Emulsion aufgesprueht werden, wobei mindestens eine Schicht aus einem hydrophob wirkenden Fett und/oder OEl besteht.{Getreidekeim; Getreidekeimprodukt; Getreidekeim, stabilisiert; Getreidekeim, ummantelt; Wirbelschichtverfahren; Nahrungsmittel; Diaetetikum}
Patent HU-196886-B (HU)
Inventor: KOEMIVES TAMAS
IPC: C07C69/738
Filed: 1985-10-01
Abstract: Die Erfindung betrifft ein Verfahren zur Herstellung von 4-Chlor-aryloxy-alkanoyl-malonester-Derivaten, die als Herbizide eingesetzt werden können. Die neuen Verbindungen haben die allgemeine Formel I, worin R exp 1 Chlor oder Methyl, R exp 2 Wasserstoff oder Chlor, R exp 3 Wasserstoff oder Methyl, R exp 4 C ind 1 ind 4 Alkyl und X-N = oder -Ch = bedeuten. Beispielsweise wird 2-(2',4',5'-Tichlor-phenoxy)-propionsäure zuerst mit Pivaloylchlorid und dann mit Methyl-propyl-äthoxy-magnesium-malonat umgesetzt, wobei man 2-(2',4',5'-Trichlor-phenoxy)-propionyl-malonsäuremethyl-propyl-ester erhält. Formel I.{Verfahren, Herstellung, 4-Chlor-aryloxy-alkanoyl-malonester-Derivate, Herbizide, 2-(2',4',5'-Trichlor-phenoxy)-propionsäure, Pivaloylchlorid, methyl-propyl-äthoxy-magnesium-malonat, 2-(2',4',5',-Trichlor-phenoxy)-malonsäuremethyl-propyl-ester}
Patent HU-201800-B (HU)
Title: Process for increasing the production of t-pa and scu-pa
Inventor: RAPPAPORT RUTH
IPC: C12N5/08
Filed: 1986-09-30
Abstract: The invention concerns a method of enhancing the production of tissue plasminogen activator (t-PA) and/or single chain urokinase plasminogen activator (SCU-PA) in normal human diploid lung fibroblast cell cultures in a serum-free medium comprising adding to said culture heparin or low molecular weight heparin and an endothelial cell growth factor.
Patent HU-208182-B (HU)
Inventor: FUELOEP JOZSEF
IPC: G01R19/255
Filed: 1985-12-20
Abstract: A találmány szerinti eljárás során a két vizsgált jelet egy-egy jelcsatornán vezetik keresztül, miközben az egyik jelcsatorna jelének nullaátmenete és másik jelcsatorna jelének ezt követő nullaátmenete közötti időt mérik, mégpedig úgy, hogy az egyik jelcsatorna pozitív meredekségű, felfutó nullaátmenetével indított és a második jelcsatorna ezt követő pozitív meredekségű, felfutó nullaátmenetével leállított időméréssel egy első idő-, illetve fáziskülönbség értéket jellemző jelet, ezt követően az egyik jelcsatorna negatív meredekségű, lefutó nullaátmenetével indított és a második jelcsatorna ezt követő negatív meredekségű, lefutó nullaátmenetével leállított időméréssel egy második idő-, illetve fáziskülönbség értéket jellemző jelet képeznek, végül pedig az első és a második idő-, illetve fáziskü- lönbség értéket jellemző jelből azok átlagértékével arányos jelet képeznek. A találmány szerinti kapcsolási elrendezésnél a két jelcsatornában vezérelhető fázisfordító (21, 22) van, amelyek kimenetei (19, 20) a jelek azonos irányú nullaátmenetei közötti idővel arányos idejű impulzusokat előállító elrendezés (27), például bistabil multivibrátor bemenetelre (25, 26) kapcsolódnak, ennek kimenete (28) időátlagoló (30) bemenetére (29), továbbá a fázisfordítókat félperiódusonként átkapcsoló jeleket előállító logikai kapcsolás (32) bemenetére (33)   kapcsolódik és a logikai kapcsolás (32) kimenete (34)   a vezérelhető fázisfordítók (21,22) vezérlő bemenetelre (23, 24) van csatlakoztatva.  HU 208182 B A leírás terjedelme: 10 oldal (ezen belül 3 lap ábra)
Patent HU-207964-B (HU)
Title: Method for producing hydrogel shaped bodies of determined form
Inventor: KINDT-LARSEN TURE
IPC: B29D11/00
Filed: 1990-12-14
Abstract: Shaped hydrogel articles such as soft contact lenses are prepared by (1) molding or casting a polymerization mixture comprising: (a) a monomer mixture comprising a major proportion of a hydrophilic (meth)acrylate ester such as 2-hydroxyethyl methacrylate, an alkyl (meth)acrylate wherein the alkyl group contains at least four carbon atoms, and a cross-linking monomer; and (b) a water-displaceable diluent, wherein said diluent has a viscosity of at least 100 MPa Sec at 30 DEG C, and wherein said diluent consists essentially of a boric acid ester of certain dihydric alcohols, said dihydric alcohols having Hansen polar (wp) and Hansen hydrogen bonding (wh) cohesion parameters falling within the area of a circle defined as having a center at wh = 20.5, wp = 13, and a radius of 8.5, to produce a shaped gel of a copolymer of said monomers and said diluent, and (2) thereafter replacing said diluent with water.