baber/WOPTO huggingface dataset:
Patent JP-2001517161-A (JP)
Title: ディジタル装飾システム
IPC: G06K15/02
Filed: 1998-01-27
Abstract: (57)【要約】
選択された画像を物品（２６）の表面（２５）に転写するディジタル装飾システム（１０）は、感熱式ヘッド（４２）と、プリントヘッド（４２）と物品（２６）の表面（２５）の間に相対運動を生成する送り機構（２２）と、画素よりなる感熱線と物品の表面（２５）の間に選択された大きさの圧力を作用させる力部材（４１）を備える。感熱式プリントヘッド（４２）は、プリントヘッド（４２）の表面の画素よりなる感熱線に熱を供給するように構成される、エネルギーを付与できる複数のヒータ要素を備える。ディジタル装飾システム（１０）はマイクロコントローラ（１６）も備え、コントローラは、プリントヘッド（４２）と、力部材（４１）と、送り機構（２２）に適切に作用するように結合され、感熱線の画素に選択して熱を供給し、また運動を生じさせる制御信号を生成し、その結果、２次元アレイの画素によって、２次元画像が物品表面（２５）に熱転写される。マイクロコントローラ（１６）は、画像に対応する画素を周画素と内部画素に分類し、各画素に供給されるエネルギーレベルを、画素に前に供給されたエネルギーのレベルと、隣接する画素に供給されるエネルギーのレベルと、画像を表面（２５）に熱転写するために画素において必要とされるエネルギーのレベルと、によって協同して作用するように制御する。
Patent JP-2001511039-A (JP)
Title: 膨張可能な止血具
IPC: A61B17/135
Filed: 1997-02-07
Abstract: (57)【要約】
本発明は、１回限り使用型の空気クッション装置（２）に関する。該装置(２)は、基部板（４）と、該基部板（４）に取りつけられた膨張可能な空気クッション（８）とを備えている。空気クッション（８）は、クッション面と一体で且つ傷口との接触領域に対応する補強部分（１６、２０）を備えている。
Patent JP-2000508655-A (JP)
Title: ヒドロフルオロエーテルの製造方法
IPC: C07C41/01
Filed: 1996-08-02
Abstract: (57)【要約】
簡潔にいうと、１つの実施例において、この発明は（１）極性のアプロティック溶剤中で、a)カルボニル含有フッ素化化合物と、b)フッ化物イオンの無水供給源と、c）第三または芳香族アミンと、d）任意に、有効量の相間移動触媒と、を配合することと、（２）前記得られた混合物をアルキル化剤と接触させることと、（３）ヒドロフルオロエーテルを前記得られた生成物の混合物から回収することと、を含む第一および第二ヒドロフルオロエーテル化合物を調製するための改良されたアルキル化方法を提供するものである。
Patent JP-2000509895-A (JP)
Title: 高圧放電ランプの製造方法
IPC: H01J61/36
Filed: 1997-10-01
Abstract: (57)【要約】
本発明は、イオン化可能な封入物が内部に封入され電極（Ｅ１、Ｅ２）が内部に設けられ少なくとも一つの密封端（１ｂ）およびこの密封端（１ｂ）から突出した少なくとも一つのリード（３ｂ）を有し、その少なくとも一つの密封端（１ｂ）が片側を開いた管状延長部（ｃ）を有し、この管状延長部（ｃ）の中を少なくとも一つのリード（３ｃ）が延びている放電管（１）が製造過程の経過において予め製造されて準備される高圧放電ランプの製造方法に関する。本発明に基づいてこの製造方法は、ガラス粒（６）を管状延長部（１ｃ）の中に詰め込み、少なくとも一つのリード（３ｂ）と管状延長部（１ｃ）との間の中間空間をガラス粒（６）で充填する工程と、管状延長部（１ｃ）を加熱により閉鎖する工程とを有している。
Patent JP-2001516222-A (JP)
Title: エチレン及び病原感受性植物遺伝子
IPC: C12N5/10
Filed: 1998-03-18
Abstract: (57)【要約】
本発明はエチレン非感受性EIN座核酸配列及び相当するアミノ酸配列に関する。
Patent MD-20020194-A (MD)
Title: Panel with shifting symbols
Inventor: VREMEA RUSLAN
IPC: G09F7/16
Filed: 2002-07-30
Abstract: The invention relates to a device, used for public information about frequently shifting specific symbols (prices, currency rates, dates etc.).The panel contains blocks, wherein there are placed segments having the possibility of rotating about its own axis. The segments may have any configuration, the colour of one side of the segment differing from the colour of the other side thereof. Onto the surface of the segments there is deposited the information.Fig. 3
Patent MX-159783-A (MX)
Inventor: VOS EDDY
IPC: B65D47/40
Filed: 1984-07-20
Abstract: A pouring adapter insert for bottles containing liquid products, allowing quick delivery of the desired quantity of liquid without spurting or glugging.
Patent NZ-201532-A (NZ)
Title: Heterocyclyl-substituted amides;fungicides and herbicides
Inventor: KAY I T
IPC: C07D231/12
Filed: 1982-08-09
Abstract: Compounds of the formula (I)wherein R<sup>1</sup> is optionally substituted phenyl, or heterocyclyl; X is a 5-membered hetero aromatic ring linked through a ring nitrogen atom; and Y is CN, CSNH<sub>2</sub>, or an ester or amide group. The compounds are useful as herbicides and fungicides.
Patent NZ-205194-A (NZ)
Title: Diagnostic device for detection of dehydrogenases and/or oxidases
Inventor: STEINBACH R W
IPC: C12Q1/26
Filed: 1983-08-09
Abstract: A diagnostic device for the detection of an increased concentration of dehydrogenases and/or oxidases in the fluids of humans, animals or plants, which consists of a carrier which bonds a redox dyestuff, and a substance mixture, adjusted to a pH value in the acid range, of the substrate corresponding to the particular dehydrogenase, a hydrogen donor compound and at least one redox dyestuff is described. The device has the peculiarity that the carrier contains polar groups and the substance mixture for detecting exclusively pathologically increased concentrations of the particular dehydrogenase and/or oxidase is adjusted to a pH value of below 5.0. The device is suitable for diagnosing malignant growths in very different organs, for example in the female genital area.
Patent NZ-237189-A (NZ)
Title: N-(4-piperidinyl)(dihydro benzofuran or dihydro-2h-benzopyran) carboxamide derivatives and pharmaceutical compositions
Inventor: DAELE GEORGES HENRI PAUL VAN
IPC: A61P1/10
Filed: 1991-02-21
Abstract: Benzamide piperidinyl cpds. of formula (I) and their salts N-oxides and isomers are new. A = CH2-CH2-, -CH2-CH2-CH2- or -(CH2)4- where 1 or 2 H of these radicals may be replaced by 1-6C alkyl. R1 = H or halo. R2 = H, NH2, mono- or di(1-6C alkyl)amino or 1-6C alkylcarbonylamino. R3 = H or 1-6C alkyl. L = 3-6C cycloalkyl; 5-6C cycloalkanone, 3-6C alkenyl (opt. substd. with aryl), -Alk-R4, -Alk-X-R5, -Alk-Y-COOR7 or -Alk-Y-CONR9R10. Alk = 1-6C alkanediyl. R4 = H, CN, 1-6C alkylsulphonylamino, 3-6C cycloalkyl, 5-6C cycloalkanone, aryl, di(aryl)methyl or Het. R5 = H, 1-6Calkyl, hydroxy-1-6C alkyl, 3-6C cycloalkyl, aryl or Het. X = O, S, SO2 or NR6. R6 = H, 1-6C alkyl or aryl. R7 = H, 1-6C alkyl, 3-6C cycloalkyl, aryl aryl-(1-6C alkyl) di(aryl)methyl, 1-6C alkyloxy or OH. Y = NR8 or a direct bond. R8 = H, 1-6C alkyl or aryl. R9, R10 = independently H, 1-6C alkyl, 3-6C cycloalkyl, aryl or aryl-1-6C alkyl, or R9 and R10 together form an opt. substd. pyrrolidinyl piperidinyl, piperazinyl or 4-morpholinyl radical. Aryl = opt. substd. phenyl. Het = a five or six-membered heterocyclic with 1,2,3 or 4, of S, S or N. (I) are new when L = H. 3 cpds. are specifically claimed e.g. 5-amino-6-chloro-3,4-dihydro-N- (1-tetrahydro-2-furanyl)- methyl)-4-piperidinyl)-2H-1 -benzopyran-8-carboxamide.
Patent NZ-237935-A (NZ)
Title: Calcined clay slurry (aqueous) stabilised by an anionic emulsion copolymer; its use in paint, paper and coatings
Inventor: LEIN GEORGE MAX
IPC: C09K8/60
Filed: 1991-04-24
Abstract: A stabilized aqueous calcined clay slurry and a method for preparing the same are provided. The method involves preparing an aqueous slurry of calcined clay containing at least 10% by weight calcined clay, and 0.05% to 1.0% by weight of anionic emulsion copolymer.
Patent NZ-247967-A (NZ)
Title: Lactoferrin receptor proteins obtained from bacterial pathogens and their use in vaccines
Inventor: SCHRYVERS ANTHONY BERNARD
IPC: A61K/
Filed: 1990-04-27
Abstract: The present invention relates to a method for isolating and purifying transferrin and lactoferrin receptor proteins from bacterial pathogens by affinity chromatography and to the preparation of vaccine antigens containing the purified receptor proteins.
Patent NZ-252563-A (NZ)
Title: Dyeing wool; process including use of an anionic dye and immersion of the article to be dyed in a bath of liquid solvent for the anionic dye
Inventor: HOLFELD WINFRIED THOMAS
IPC: D06P3/14
Filed: 1993-05-13
Abstract: A process for the dyeing of a fibrous article containing wool with an anionic dye and products processed thereby. The process includes immersing the article in a dyeing bath of a liquid solvent for the anionic dye. The liquid solvent and the article are heated to a temperature at least equal to the dyeing transition temperature. At least a portion of the dye is added as a miscible liquid concentrate while the solvent and the article are up to temperature. Stirring of the bath during the dye addition period and while the solvent and article are up to temperature is done to mix the dye concentrate with the solvent to form a dilute dye solution and to provide a flow of the dilute dye solution relative to the article to cause, on the average, essentially uniform dye transport of the anionic dye to the article. The dye addition rate is adjusted so that the dye addition rate is the primary control over the rate of dye uptake by the article.
Patent NZ-255158-A (NZ)
Title: Human growth hormone; stable pharmaceutically acceptable aqueous formulation and means for preparing and storing it
Inventor: O'CONNOR BARBARA H
IPC: A61K38/27
Filed: 1993-07-29
Abstract: A stable pharmaceutically acceptable aqueous formulation containing human growth hormone, a buffer, a non-ionic surfactant, and, optionally, a neutral salt, mannitol, or, a preservative, is disclosed. Also disclosed are associated means and methods for preparing, storing, and using such formulations.
Patent NZ-256188-A (NZ)
Title: Dna encoding c100-r (receptor for the beta-amyloid precursor protein) its production using engineering host cells and its use in identifying c100 ligand antagonists
Inventor: MANLY SUSAN P
IPC: C12P21/08
Filed: 1993-08-31
Abstract: The present invention relates to the cloning of  beta APP-C100 receptor (C100-R), and genetically engineered host cells which express the C100-R. Such engineered cells may be used to evaluate and screen drugs and analogs of  beta -APP involved in Alzheimer's Disease.
Patent NZ-259866-A (NZ)
Title: Topical composition, ketoconazole plus a acetonide glucocorticosteroid, use of ketoconazole in compositions
Inventor: FRANCOIS MARC KAREL JOZEF
IPC: A61P29/00
Filed: 1994-01-12
Abstract: PCT No. PCT/EP94/00092 Sec. 371 Date Jun. 14, 1995 Sec. 102(e) Date Jun. 14, 1995 PCT Filed Jan. 12, 1994 PCT Pub. No. WO94/16710 PCT Pub. Date Aug. 4, 1994The present invention relates to a topical oil-in-water emulsion composition comprising ketoconazole, an acetonide glucocorticosteroid and a dermatologically acceptable carrier, characterized by a pH above 2.5 and below 6, and a method of preparing said composition.
Patent NZ-264255-A (NZ)
Title: Package for array of cans including plastics band and paperboard cover
Inventor: WEAVER WILLIAM N
IPC: B65D71/50
Filed: 1994-08-17
Abstract: A can package (10) is disclosed, including an array of cans (12) disposed in longitudinal rows and transverse ranks. A first carrier member (16) of resilient, flexible, plastic material includes a similar array of apertures respectively receiving can bodies (20). A second carrier (18) member of self-supporting sheet material such as paperboard includes a top panel (32) overlying chimes (24) of the cans (12) and opposite side panels (34, 36, 38, 40) extending down along opposite sides of the cans (12) and secured to the plastic carrier member (16). Slits (44, 46, 48, 50, 52) are formed in the second member (18) at junctions between the top panel (32) and the side panels (34, 36, 38, 40) for presenting opposing edges respectively extending over and engaging beneath chimes (24) of the cans. This engagement of the second carrier (18) beneath the chimes (24) facilitates lifting of the package when it is lifted by the second carrier, for example by using hand grips (102, 104, 106, 108).   <IMAGE>
Patent NZ-302009-A (NZ)
Title: Taste masking liquids for medicinal preparations
Inventor: DASS POPLI SHANKAR
IPC: A61K9/00
Filed: 1996-01-16
Abstract: There is provided a pharmaceutically acceptable taste masking liquid excipient base for administration of relatively large amounts of unpleasant tasting medicines, said excipient base having higher than normal viscosities due to a combination of polyethylene glycol and cellulosic material.
Patent NZ-306391-A (NZ)
Title: Acellular pertussis vaccines comprising purified toxin, filamentous haemagglutinin, pertactin and fimbrial agglutinogins
Inventor: VOSE JOHN R
IPC: A61K39/116
Filed: 1996-05-02
Abstract: Vaccine for protecting humans against Bordetella pertussis infection comprises pertussis toxoid (I), filamentous haemagglutinin (II), pertactin (III) and agglutinogens (IV) of B. pertussis in relative amts. able to confer protection to >= 70% of an at-risk population. A single dose is 5-30 mu g (I) and (II), 3-15 mu g (III) and 1-10 mu g (IV), all expressed as nitrogen contents, esp. 10 mu g (I) and 5 mu g (II) or 20 mu g each of these, plus 5 mu g (III) and 3 mu g (IV). Vaccines are administered by subcutaneous or intramuscular injection. (IV) comprises fimbrial agglutinogens (Agg) 2 and 3 (pref. at ratio 1.5-2:1) but is free of Agg 1. These may also include diphtheria toxoid, pref. at 15 Lfs, and tetanus toxoid, pref. at 5 Lf, opt. also other non-Bordetella antigens. They can also include an adjuvant, specifically alum.
Patent NZ-315832-A (NZ)
Title: Issuing of electronic coupons over the internet
Inventor: GOLDEN STEVEN M
IPC: G06Q40/00
Filed: 1996-07-25
Abstract: A data processing system issuing electronic certificates through "online" networks of personal computers, televisions, or other devices with video monitors or telephones. Each electronic certificate includes transaction data and identification data, and can be printed out on a printing device linked to a consumer's personal input device, or electronically stored in a designated data base until a specified expiration date. The certificate can be used for various purposes, including use as a coupon for a discounted price on a product or service, proof of a gift or award, proof of reservation, or proof of payment. Consumers access the data processing system online, browse among their choices, and make their selections. The data processing system provides reports on the selected certificates and their use following selection. Certificate issuers also have online access to the data processing system and can create or revise offers, and provide various instructions pertaining to the certificates, including limitations as to the number of certificates to be issued in total and to each individual consumer.
Patent NZ-331573-A (NZ)
Title: Seal comprising at least one bendable spacer element embedded or partially embedded in core material
Inventor: BARATUCI JAMES LYNN
IPC: B29C48/08
Filed: 1997-02-26
Abstract: A unitary seal 300 is claimed, the seal comprising at least one core material 300 (24) continuous along the length of the seal, at least one spacer element 310 (25) continuous along the length of the seal, partially embedded in or embedded in the core material and having a greater width than thickness, and at least one longitudinal adhesive film 330 (26) continuous along the length of the seal and which coats at least one surface of the core material, the adhesive film being compositionally different than the core material. The spacer element is bendable perpendicular to, or along any line parallel to, its width to an angle from 2 to 150o  without changing the width of the spacer element more than one tenth of one percent.  The core material may include a foamed polymeric material.  A structure comprising at least first and second transparent or translucent panel members 22, 23 including the unitary seal located along the peripheries of the members and in physical contact with the facing surfaces of the members, is also claimed.
Patent NZ-335086-A (NZ)
Title: Bacillus thuringiensis pesticidal toxins and nucleotide sequences which encode these toxins
Inventor: FEITELSON JERALD S
IPC: C12Q1/689
Filed: 1997-10-30
Abstract: The use of and compositions that comprise red yeast fermentation products are disclosed.  The compositions can be used as natural dietary supplements and/or medicaments for the treatment or prevention of hyperlipidemia and associated disorders and symptoms, such as cardiovascular diseases, cerebrovascular diseases, diabetes, hypertension, obesity, asthenic breathing, chronic headache, chest pain and tightness, limb swelling and distention, loss of appetite and excess expectoration. The compositions are effective in lowering both the serum cholesterol and serum triglyceride levels in humans, and can be used for maintaining cardiovascular health. The composition also encompasses particular Monascus strains that yield fermentation products with the desired biological activities.
Patent NZ-336142-A (NZ)
Title: Method of manufacturing indiffused optical waveguide structures in a substrate
Inventor: CARMANNINI CARLO
IPC: G02B6/134
Filed: 1999-06-04
Abstract: An indiffused optical waveguide in a substrate 1 is formed by etching a metal layer 7 deposited on a substrate 1 and covered with a resist layer 8  mask pattern 4 by a chemical/physical etching technique to expose substrate 1 and by diffusing the remaining metal layer structure into the substrate by a heat treatment.
Patent NZ-336611-A (NZ)
Title: Polymer composition comprising phenols
Inventor: BEESE ULRICH
IPC: B29C48/16
Filed: 1999-01-08
Abstract: A waste container made from a polymer composition.  The polymer composition contains a polymer selected from among polyolefins, styrene polymers and polymers containing halogen, except for soft PVC, linear polyesters, linear polycarbamates, high temperature resistant plastics as well as recycled material stemming from these types of plastic.  Te composition also contains 0.01% to 10% by weight of at least one phenol in the form of a halogenated  dihydroxydiphenyl methane, dihydroxydiphenyl sulfide, dihydroxydiphenyl ether and/or 2,4,4'-trichloro-2'-hydroxydiphenyl ether, except for the dihydroxydiphenyl sulfides 2,2'-thiobis(6-halogen-4-C1-8-alkyl phenol) and 2,2'-thiobis(6-halogeno-4-C2-8-alkenyl-phenol).  The phenol additive acts as a biocide to provide the container with a disinfecting effect.
Patent NZ-337088-A (NZ)
Title: Animal fibre removal apparatus comprising rotatable blades
Inventor: NEUSTROSKI JOHN RUSSEL
IPC: C14B19/00
Filed: 1999-08-05
Abstract: Blades 4 (typically two radially opposed blades) are rotated to successively pass adjacent an opening 10 in work surface 11.  This apparatus is stated to be effective in plucking opossums, rabbits and other small to medium sized animals.
Patent NZ-500369-A (NZ)
Title: Preparation of an aggregate comprising a carbon phase, a silica-containing species phase and/or a metal-containing species phase, in a multistage reactor
Inventor: KUTSOVSKY YAKOV E
IPC: C08K3/00
Filed: 1998-04-17
Abstract: This method of making a multi-phase aggregate involves introducing a first feedstock into a first stage (9) of a multi-stage reactor, and introducing a second feedstock into the reactor at a location (10) downstream of the first stage. The first and second feedstocks comprise a carbon black-yielding feedstock, and at least one feedstock also comprises a silicon-containing compound. The reactor is operated at a sufficient temperature to decompose the silicon-containing compound and to pyrolize the carbon black-yielding feedstock. An alternative method of making the aggregate involves a multi-stage reactor having at least three stages for introducing a feedstock, wherein at least one of the feedstocks comprises a carbon black-yielding feedstock and wherein at least one of the feedstocks comprises a silicon-containing compound. Besides producing the aggregate comprising a carbon phase and a silicon-containing species phase, silica and/or carbon black may also result from the process. A further alternative involves making an aggregate comprising a carbon phase and a metal-containing species phase using a multi-stage reactor having at least two stages for introducing feedstocks.  At least one of the feedstocks comprises a carbon black-yielding feedstock and another comprises a metal-containing compound. The aggregates when incorporated into elastomeric compositions preferably lead to improved wet skid resistance and rolling resistance properties.
Patent NZ-501397-A (NZ)
Title: Label, to close together a container of two parts, releasably adhered to a web
Inventor: FARR PAUL GEORGE
IPC: G09F3/10
Filed: 1999-11-29
Abstract: A two-part or hinged container is retained in the closed position by a self-adhesive label 14. The labels are releasably adhered in side-by-side alignment, to a web, and folded with the web so at least part of the display face is folded on itself. The web is cut at the fold and on each side of part of the label. Part of the label is adhered to a container before filling and after closing the container the end 36 of web portion 32 is pulled to adhere portion 30 across the line of closure/opening. The label may also act as a tamper evident seal.
Patent NZ-502100-A (NZ)
Title: A squeeze lock resistant type closure with tamper evident ring
Inventor: BUSH ANDREW MICHAEL
IPC: B65D50/04
Filed: 1999-12-23
Abstract: A tamper evident squeeze lock closure with a tamper evident ring for a container (2) is disclosed.  The closure has an inner skirt (8) and an outer skirt (7); the inner skirt (8) is threaded for engagement with a complementary thread of a container neck (3).   The outer skirt has at least two locking lugs (17), which each engage with complementary cam locks (5,6) on the container neck (3), and a tamper-evident ring (11) connected by fragile connectors (12) to the outer skirt.   The tamper evident ring (11) has sections (13), alongside the locking lugs (17) and a space adjacent thereto into which the cam locks (5,6) fit when the closure is located on the container neck (3), which are spaced radially relative to the remainder of the tamper evident ring.   The sections (13) of the tamper evident ring (11) are stepped relative to the remainder of the ring to thereby form the space adjacent the locking lugs (17), which are at a level with the remainder of the ring so that one of the cam locks (5,6) fits in each space when the closure is located on the container (2).
Patent NZ-502750-A (NZ)
Title: Vaccination against Neisseria meningitidis disease using Neisseria outer membrane protein (OMP) in particular, lactoferrin binding protein B (LbpB)
Inventor: PETTERSSON-FERNHOLM ANNIKA MAR
IPC: C12N1/21
Filed: 1998-08-10
Abstract: LbpB polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing LbpB polypeptides and polynucleotides in the design of protocols for the treatment of neisserial disease, among others, and diagnostic assays for such conditions.
Patent NZ-503262-A (NZ)
Title: Hepatitis C NS3 protease inhibitor peptides and peptide analogues
Inventor: WERNIC DOMINIK
IPC: A61P31/12
Filed: 1998-08-10
Abstract: A compound of formula (I), wherein; Q is CH2 or N-Y, wherein Y is H or alkyl; a) when Q is CH2, a is 0, b is 0, and B is an amide derivative of formula R11aN(R11b)-C(O)- wherein R11a is H; alkylcycloalkyl optionally substituted with carboxy; alkoxycarbonyl; arylakyl; 2-tetrahydrofuranylmethyl; thienylmethyl; thiazolidylmethyl; alkyl optionally substituted with carboxyl or dialkylamino; cycloalkyl;aryl;alkylaryl; cycloalkylalkyl; heterocyclealkyl; R11b is alkyl substituted with carboxyl, alkoxycarbonyl or phenylmethoxycarbonyl; aralkyl substituted on the aromatic portion with carboxyl, alkoxycarbonyl, phenylmethoxycarbonyl or heterocyclealkyl; or R11a and R11b jointly form an optionally substituted 3 to 7-membered nitrogen-containing ring; or b) when Q is N-Y; a and b are 0 or 1, and B is of formula R11-C(O)-wherein R11 is (i) alkyl optionally substituted with carboxyl, alkanoyloxy or alkoxy;  (ii) cycloalkyl optionally substituted with carboxyl, alkoxycarbonyl or phenylmethoxycarbonyl; (iii) cycloalkyl substituted with carboxyl and one to three alkyl substituents; (iv) optionally substituted alkylcycloalkyl;     (v) a compound (A); or (iv)optionally substituted aryl or alkyl; R6 and R6 are alkyl substituted with carboxyl; or c) when Q is either CH2 or N-Y-; R4 is alkyl, cycloalkyl or alkylcycloalkyl; Z is oxo or thioxo; R3 is optionally substituted alkyl; W is a group of formula (II), wherein R2 is alkyl, aryl, aralkyl or optionally substituted cycloalkyl; or W is a group of formula (II') wherein X is CH or N; R2' is an optionally substituted alkylene which forms a ring with the attached carbon atom and X; or X is CH or N and R2 is alkylene which forms a ring with X and the attached carbon and fused to a second optionally substituted ring; R1' is H; R1 is alkenyl or optionally substituted alkyl or R1 and R1' together form an optionally substituted 3-6 membered ring; and A is hydroxy or salt thereof.