baber/WOPTO huggingface dataset:
Patent FI-102294-B1 (FI)
Inventor: JONASSEN IB
IPC: C12P21/02
Filed: 1990-12-19
Granted: 1998-11-13
Abstract: The invention relates to insulin precursors having the amino acid sequence  B(1-29)-X1-X2-Y2-Y1-A(1-21) wherein B(1-29) are the 29 first amino acid residues of the B chain of human insulin, A(1-21) are the 21 amino acid residues of the A chain of human insulin, X1 represents a peptide bond or one or more amino acid residues, X2 represents Glu or Asp, and Y1 and Y2 each represent Lys or Arg, the positions A6 and A11, A7 and B7 and A20 and B19, respectively, being connected through sulphur bridges, and, optionally, one or more of the amino acid residues of chains B(1-29) and A(1-21) are substituted by another amino acid residue. The insulin precursors are prepared by culturing a yeast strain transformed with a replicable expression vehicle comprising a DNA sequence encoding the insulin precursor and isolating it from the culture medium. The insulin precursors can be converted into human insulin or insulin analogues by enzymatic treatment.
Patent FI-101765-B1 (FI)
Inventor: DAVIS ELIZABETH JEAN
IPC: A61F13/15
Filed: 1992-10-30
Granted: 1998-08-31
Abstract: A sanitary napkin having flaps folded over the topsheet. This arrangement helps to maintain the topsheet in a sanitary condition and is more convenient for the wearer than a configuration having the flaps folded over the backsheet. The flaps may be maintained in this folded arrangement by a unitary release strip which bridges the flaps and covers any adhesive used to attach the flaps to the undergarment. If desired, the release paper may further wrap the longitudinal side margins of the sanitary napkin to additionally cover adhesive disposed on the central portion of the backsheet. If desired, the flaps may be folded over the topsheet, overlap each other and be adhesively joined to the other flap.
Patent FI-102473-B1 (FI)
Inventor: BERGSTROEM CHRISTER
IPC: C07C13/42
Filed: 1996-03-13
Granted: 1998-12-15
Abstract: Disclosed is a method for the preparation of norbornene and substituted norbornene compounds via a Diels-Alder reaction, in which a cyclic diene is reacted with an olefinic compound in order to prepare a norbornene compound. According to the invention a cyclic diene is gradually added to react with an olefinic compound, in order to keep the concentration of the cyclic diene in the reaction mixture as low as possible during the reaction. It is possible to obtain a very pure product, high yield, short reaction time and high concentrations of the exo diastereomer with the method of the invention.
Patent IE-44962-B1 (IE)
Title: The manufacture of steel wires
IPC: B22D11/00
Filed: 1977-05-27
Abstract: A nozzle for the production of steel wires having a small diameter by the extruding of a molten steel under pressure through the nozzle is made essentially of zirconia(ZrO2), possibly containing a small amount of magnesia and/or a rare earth oxide selected in such a manner that, in the presence of silicon and/or silica, it does not give rise to silicates of low melting point, said oxide preferably being yttrium oxide (Y2O3).
Patent IE-48916-B1 (IE)
Title: Pasta of lasagna type
IPC: A23L7/109
Filed: 1979-08-08
Abstract: An Italian pasta ribbon-like product comprises a row of longitudinally marshalled undulations 11, 12 and continuously scalloped edges 13 and 14, to prevent the warping of the pasta ribbon upon drying and long storage.
Patent IE-45768-B1 (IE)
Title: Pharmaceutical compositions containing pirbuterol and hydroxyzinc
IPC: A61K31/445
Filed: 1977-08-25
Abstract: A pharmaceutical composition in effective dosage unit form for enhancing pulmonary function in mammals comprising either (a) pirbuterol and hydroxyzine or (b) a pharmaceuticallyacceptable acid addition salt of each of pirbuterol and hydroxyzine, the said composition comprising pirbuterol and hydroxyzine in the weight ratio, calculated as the free base of each, of from 1:0.3 to 1:5; and the use of such composition for enhancing pulmonary function in a mammalian subject.
Patent IE-38445-B1 (IE)
Title: Catheter insertion device
IPC: A61M25/06
Filed: 1973-06-21
Abstract: A catheter insertion device having a needle assembly comprising a hollow slotted needle with a needle hub affixed to its proximal end and a catheter assembly comprising a flexible catheter having a sealing segment with an enlarged outside diameter to prevent bleedback and a hollow catheter hub secured to its proximal end, the two assemblies being releasably locked together to prevent relative longitudinal movement of the catheter in the needle, the locking being releasable without relative longitudinal movement of the catheter and needle. The catheter is provided with a wire stylet having an enlarged rounded distal tip.
[US3827434A]
Patent IE-46153-B1 (IE)
Title: Bicyclic antibacteial agents
IPC: A61K31/397
Filed: 1977-09-07
Abstract: Intermediates and methods for preparing a new series of 7-acylamino-8-oxo-3-oxa-1-azabicyclo[4.2.0]-octane-2-carboxylic acid derivatives are described. The end product compounds have antibacterial activity especially against certain Gram negative organisms.
Patent IE-36187-B1 (IE)
Title: Phenoxy and phenylthio compounds
IPC: C07D333/76
Filed: 1972-03-20
Abstract: 1364806 Substituted tricyclic furans and thiophenes F HOFFMANN-LA ROCHE & CO AG 24 March 1972 [26 March 1971] 13877/72 Heading C2C Novel compounds of the Formula I wherein R 1 and R 2 are independently hydrogen, halogen, C 1-7 alkyl, C 1-7 alkoxy, C 1-7 alkylthio, trifluoromethyl, cyano, carbamoyl, carboxy, C 1-7 alkoxycarbonyl, nitro, amino, mono-(C 1-7 alkyl) amino, di-(C 1-7 alkyl) amino, acyl, acylamido, sulphamoyl, di-(C 1-7 alkyl) sulphamoyl, or difluoromethylsulphonyl; R 3 is hydrogen, C 1-7 alkyl, amino-C 1-7 alkyl, mono-(C 1-7 alkyl) amino-C 1-7 alkyl, di-(C 1-7 alkyl) amino C 1-7 alkyl; n is 1 or 2 and X is oxygen or sulphur, may be prepared by (a) cyclizing a compound of the formula II wherein at least one position on the phenyl ring ortho to X is unsubstituted, and R<SP>1</SP> 3 is C 1-7 alkyl, (b) treating a compound IIa wherein R<SP>1</SP> 1 and R<SP>1</SP> 2 are independently hydrogen, nitro, trifluoromethyl, C 1-7 alkoxycarbonyl, cyano or acyl (at least one of R<SP>1</SP> 1 and R<SP>1</SP> 2 being other than hydrogen) with an acidic catalyst to yield an appropriate substituted compound I in which X is oxygen, and (c) interconversion of substituents on I by known methods and separation of isomers, i.e. resolution, conversion to a salt with acid or base, saponification of a carboxylic ester group, conversion of a salt of compound I wherein R 3 represents hydrogen into a compound I wherein R 3 represents other than H or alkyl, reduction of a nitro to an amino group, conversion of an amino group into a diazonium salt and thence into hydrogen, halogen, cyano, hydroxy or alkoxy. Compounds of Formula IIa above are prepared by reacting compounds and Cycloalkanes of Formula IV are obtained by halogenating the corresponding halogen free compound. Pharmaceutical compositions having antiinflammatory and anti-rheumatic activity and which are useful for oral, enteral or parenteral administration, contain the above novel compounds I.
[GB1364806A]
Patent IE-47518-B1 (IE)
Title: Indolo (2,3-a) quinolizidines,preparation and therapeutic use
IPC: C07D209/00
Filed: 1978-11-24
Abstract: The invention relates to a multistep preparation process of new indolo(2,3-a)quinolizidines of the general formulae (I) and (II): (I) (II) wherein R stands for -COOC2H5, -COOH, -CN, a primary or secondary methylenamino group, a methylenamido group, or wherein R, together with the ring nitrogen of the indolo ring, represents one of the groupings N-CO-NH-CH2 or N-CO. These compounds of the invention are useful in the field of blood circulation in the brain.
Patent IE-59131-B1 (IE)
Title: Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and for the purification thereof
IPC: C07D291/06
Filed: 1986-09-02
Abstract: 6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide is prepared by cylcizing acetoacetamide-N-sulfonic acid or its salts with an at least approximately equimolar amount of SO3 in the presence of a water-immiscible, inert organic solvent and, if appropriate, also an inert, inorganic solvent. In the event that an equimolar amount of SO3 is employed, working up is effected by adding aqueous sulfuric acid when the cyclization reaction is complete; in the event that the amount of SO3 employed is more than equimolar, the 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide obtained in the form of the SO3-adduct is hydrolyzed by adding water or ice, whereby sulfuric acid is formed from the SO3 combined in the SO3-adduct. The inert, organic solvent is then removed from the resulting multi-phase mixture by distillation, and the 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide is obtained in a pure form from the remaining aqueous sulfuric acid phase by crystallization. Additionally, quite generally, crude 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide is purified by recrystallization from aqueous sulfuric acid. The non-toxic salts of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2 dioxide-in particular the potassium salt-are valuable synthetic sweetening agents.
[US4806639A]
Patent IE-56209-B1 (IE)
Title: Piperidinedione derivatives,processing anti-arrythmic activity,for protecting the myocardium,process for their preparation and pharmaceutical compositions containing said derivatives
Inventor: CLAUDE BERNHART
IPC: C07D401/04
Filed: 1983-11-04
Abstract: The present invention relates to derivatives of piperidinedione of formula:    <IMAGE>  (I)  in which R is alkyl or forms with N a possibly substituted morpholino or piperidino group, n=2 or 3, R1, R2, R3 and R4 represent H or lower alkyl; R3 and R4 taken together may represent (CH2)m where m=4 or 5 and R2 and R3 taken together may represent (CH2)p where p=3 or 4 and in this case R1 and R4=H, R5 is H or alkyl. It also relates to a process for manufacturing the product of formula (I) and to the drugs containing a product of formula (I).
Patent IE-44269-B1 (IE)
Title: Film forming sunscreen compositions
IPC: A61K8/34
Filed: 1976-12-02
Abstract: FILM FORMING COMPOSITION FOR SUNSCREENS AND THE LIKE A water-based, cosmetically acceptable, cream or lotion composition for producing an adherent, breathable continuous film on the skin of the user, resulting film being resistant to removal by the action of water of perspiration but readily removable by washing with a solution of soap or another emulsifier, comprises a major amount (in excess of 50% by weight) of water; a minor, effective amount of an oil soluble, hydrophobic active ingredient such as sunscreening agent; a non-ionic, oil soluble emollient, an emulsifying system comprising a member selected from the fatty acids and the carboxy vinyl polymers neutralized with ammonia or a fugitive amine; and a film-forming, water insoluble acrylic interpolymer containing carboxylic acid groups, which polymer has been solubilized by neutralizing the carboxylic acid groups with ammonia or a fugitive amine.
Patent IE-61950-B1 (IE)
Title: Spray dried acetaminophen
Inventor: REUTER GERALD LOUIS
IPC: A61K9/68
Filed: 1987-10-13
Abstract: A therapeutic taste-neutral powder form of acetaminophen is obtained by spray-drying a suspension of colloidal silica in a lower alkanol solution of acetaminophen and ethyl cellulose. The powder can be formulated into fast dissolving dosage forms, chewable tablets and the like.
Patent IE-75696-B1 (IE)
Title: Improvements in plating
Inventor: WARREN STEPHEN GEOFFREY
IPC: C25D3/50
Filed: 1989-09-06
Abstract: An effective bath for plating platinum or platinum alloys contains a complexed platinum (II) salt in which the anion component is a group or radical derived from an organic acid or inorganic acid other than a hydrohalic acid, in alkaline aqueous solution. The bath is more efficient and stable than known baths and permits good plating deposits to be achieved.
Patent IE-57332-B1 (IE)
Title: A fruit juice mix for whipped and/or frozen applications
IPC: A23G9/32
Filed: 1985-12-13
Abstract: A fruit juice mix made entirely from natural products contains at least one fruit juice source in association with 0.1 to 10 percent by weight of various stabilizers based upon the total weight of the mix. An amount of water and other ingredients is such that the blend has a brix value of from about 10 to about 35 and for more desirable results of 20 to 35. No refined sugar or corn sweetener is contained in the blend. Moreover, the juice can be frozen to. form a soft material as on the order. of soft ice cream or yogurt.
Patent IE-62194-B1 (IE)
Title: Lipid formulation systems
Inventor: NICKLASSON MARTIN
IPC: A61K8/37
Filed: 1991-09-13
Abstract: The invention relates to a lipid particle forming matrix, characterized by, that from a defined system of at least two lipid components chosen from classes of different polarity, in which at least one of the lipid components is bilayer forming, discrete lipid particles are formed spontaneously when interacting with aqueous systems. Preferably at least one of the lipid components is amphiphatic and polar and one is nonpolar. These discrete particles are formed spontaneously from the matrix without any chemical or physical treatment or initiation. The lipid particle forming matrix can contain bioactive materials, chosen from the group of drugs, herbicides, pesticides, fertilizers, food and cosmetic ingredients or additives. The invention also relates to a process for the production of the matrix, the use of the lipid particle forming matrix as a carrier system for bioactive materials and pharmaceutical composition such as oral, rectal, nasal, vaginal, ocular or parenteral vehicles, creams, ointments, capsules and tablets containing the said lipid particle forming matrix and a drug.
Patent IE-64560-B1 (IE)
Title: Digital automatic gain control
Inventor: KEPLER JAMES FRANK MICHAEL
IPC: H04J3/16
Filed: 1989-10-10
Abstract: There is provided a method of digital Automatic Gain Control (AGC) in a receiver having limited dynamic range, particularly for discontinuous signals. The method is characterized by detecting the level of a received and AGC'd discontinuous signal, comparing the level of the AGC'd signal relative to the dynamic range of the receiver, and adjusting the AGC to establish a desired relationship between the AGC'd signal and the dynamic range limitation. There is also provided a method of handoff in a TDMA cellular-type transmission system utilizing this method of AGControl. The method for Automatic Gain Control (AGC) of discontinuous signals in a receiver having limited dynamic range is further characterized by: digitizing (A/D) a received and AGC'd discontinuous signal and converting the digitized samples to a power sample to sense the power of and detect the level of the signal, comparing the level of the AGC'd signal relative to the dynamic range of the receiver; and coarsely-adjusting by either progressively attenuating the signal until it falls within the dynamic range of the receiver or by progressively gain-amplifying the signal until it falls within the limited dynamic range of the receiver and finely-adjusting the AGC of the received signal until optimum use of the full (albeit limited) dynamic range of the signal processing stages is about 6-12 dB below maximum to establish a desired relationship between the AGC'd signal and the dynamic range limitation. <IMAGE>
Patent IE-62569-B1 (IE)
Title: Topical formulations and transdermal delivery systems containing 1-isobutyl-1h-imidazo(4,5-c)quinolin-4-amine
Inventor: WICK STEVEN M
IPC: A61K47/12
Filed: 1989-12-05
Abstract: Pharmaceutical formulations and adhesive-coated sheet materials for the topical and/or transdermal delivery of 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine, including creams, ointments and pressure-sensitive adhesive compositions. Pharmacological methods of using the formulations and the adhesive-coated sheet materials of the invention in the treatment of viral infections.
Patent LU-100003-B1 (LU)
Title: Multi-functional shower bar
Inventor: LIN GUIHUA
IPC: F16K11/00
Filed: 2017-01-04
Granted: 2017-06-07
Abstract: The present invention discloses a multi-functional shower bar which includes a three-way water inflow main body, an upper pipe in seal connection with one of connectors of the three-way water inflow main body, a lower straight pipe in seal connection with another connector of the three-way water inflow main body, and a mainfold assembly in seal connection with the other end of the lower straight pipe, wherein the other end of the upper pipe is provided with a water outlet welding joint used for mounting a shower head, the upper pipe and the lower straight pipe are mutually perpendicular, an inner pipe is arranged inside the lower straight pipe, one end of the inner pipe is provided with a water sealing joint which is matched with the inner pipe to guide water into the upper pipe and allows the lower straight pipe to be in seal connection with the three-way water inflow main body, and the other end of the inner pipe is in seal connection with the mainfold assembly through a mainfold joint. The multi-functional shower bar also includes a water inflow joint and a water sealing fixed member which are interchangeably used, wherein the water inflow joint is connected with the three-way water inflow main body or the mainfold assembly, and the water sealing fixed member is connected with the three-way water inflow main body or the mainfold assembly. According to the water inflow manner provided by the present invention, the water inflow manner can be switched into upward water inflow or downward water inflow is carried out through interchange use of the water inflow joint and the water sealing fixed member
Patent LU-101349-B1 (LU)
Title: Sommier comprenant un support pour linge de lit
Inventor: COLLIGNON JEAN-FRANÇOIS
IPC: A47C21/02
Filed: 2019-08-09
Granted: 2021-02-11
Abstract: L'invention concerne un sommier de lit (1) comprenant deux courts pans (2) et deux longs pans (4) et un support (10, 20), caractérisé en ce que ledit support (10, 20) comporte au moins deux pieds (14, 24, 34) parallèles l'un à l'autre s'étendant selon une première direction et au moins un dispositif de suspension (12, 22, 32) reliés aux deux pieds (14, 24, 34) et s'étendant selon un deuxième direction perpendiculaire à la première direction, ledit support (10, 20) étant apte à adopter une position rangée dans laquelle le support (10, 20) est intégré audit sommier (1) et une position déployée dans laquelle les deux pieds (14, 24, 34) s'étendent dans un plan perpendiculaire ou incliné par rapport au plan du sommier (1) défini par les courts pans (2) et longs pans (4)
Patent LU-101526-B1 (LU)
Title: Decorative floor covering production method
Inventor: BRANKOV IGOR
IPC: E04F15/16
Filed: 2019-12-12
Granted: 2021-06-14
Abstract: A method for producing a decorative floor covering comprises digitally printing an adhesive on a printing substrate thus generating an adhesive layer forming an at least one-dimensionally patterned decorative motif. The adhesive is a radiation-curable composition, preferably essentially free from non-reactive solvents and/or from photoinitiator. The printing substrate includes one of a core structure and a wear layer. After the printing of the adhesive, the adhesive layer on the printing substrate is contacted with the other one of the core structure and the wear layer. The core structure and the wear layer are then attached to each other by electron-beam curing the adhesive layer between them.
Patent LU-101587-B1 (LU)
Title: A rapid material delivery transport device for building materials used in tunnel construction
Inventor: DENG ZHENG
IPC: B62D33/027
Filed: 2020-01-03
Granted: 2021-07-06
Abstract: The invention discloses a rapid material delivery transport device for building materials used in tunnel construction, which comprises a base-plate. A bearing frame is arranged at the bottom end of the base-plate, a walking mechanism is arranged at both sides of the bearing frame, a plurality of buffer mechanisms are arranged between the base-plate and the bearing frame, a protective mechanism is arranged at the top end of the base-plate, the ends at both sides of the base-plate are connected with strip plates through pin axis rotation, material delivery mechanism is arranged between the two strip plates, a latch mechanism is arranged between the two strip plates and the protective mechanism, and one end of the base-plate is provided with a connecting mechanism. The invention can load and protect the building materials by using the base-plate, the protective mechanism and the latch mechanism. The buffer mechanism can play a buffer protection role in the transportation of building materials; the material delivery mechanism can directly load and unload the building materials from the ground or the base-plate, improving the efficiency of loading and unloading; the walking mechanism and the connecting mechanism can connect the base-plate with the driving equipment, and make the base-plate move, so that it can further improve the efficiency of building material transportation.
Patent LU-501993-B1 (LU)
Title: Temperature-measuring thermal resistor with good anti-vibration performance
Inventor: ZHAO SHIHAI
IPC: G01K7/16
Filed: 2021-09-23
Granted: 2022-11-03
Abstract: The present invention relates to the technical field of temperature-measuring resistors, and particularly provides a temperature-measuring thermal resistor with good anti-vibration performance, comprising: a thermal resistor, a main body, a conducting wire and a protective casing, wherein the thermal resistor is located in a closed end of the protective casing; the other end of the protective casing is connected to one end of the main body; the main body is internally provided with a sliding hole having openings at two ends thereof, which are a first circular hole and a second circular hole respectively; a hollow spring fixing member is provided in the second circular hole; a hollow slider is slidably provided in the sliding hole; a first compression spring is provided between the slider and an inner wall of the main body at one end thereof; a second compression spring is provided between the slider and the spring fixing member; the thermal resistor is connected to one end of the conducting wire; and the other end of the conducting wire passes through the first circular hole, the first compression spring, the slider, the second compression spring and the spring fixing member in sequence, and is fixedly connected to the slider by means of a wire fixing member. During operation, the slider returns to an original position under the action forces of the first compression spring and the second compression spring, reducing the vibration to which the thermal resistor is subjected.
Patent LU-502818-B1 (LU)
Title: Information-based book receive device
Inventor: WU LIN
IPC: A47B96/02
Filed: 2022-09-21
Granted: 2023-03-22
Abstract: The invention relates to the technical field of informationized book management, and discloses an informationized book receiving device which comprises a receiving rack, wherein a clapboard is fixedly arranged in the middle of the receiving rack, two sides of the clapboard and two side walls of the receiving rack are fixedly provided with a plurality of placing plates, the middle of two sides of the front end surface of the receiving shelf is fixedly provided with a control panel, A scanner is fixedly arranged above the front end faces of the two control panels; mounting frames are fixedly arranged on the two sides of the upper end face of the storage rack; slots are formed on the two sides inside the upper end of the storage rack; fixing rods are fixedly arranged inside the two slots; motors are fixedly arranged in the middle parts of the two fixing rods; and fan blades are fixedly connected to the output ends of the motors. Accord to that device disclosed by the invention, the information-based book storage management can be realize, and the inside of the storage rack can be ventilated, so that the moisture-proof effect of the storage rack is improved.