baber/WOPTO huggingface dataset:
Patent CZ-298089-B6 (CZ)
Title: Cell adhesion inhibitors, process of their preparation and pharmaceutical compositions in which the cell adhesion inhibitors are comprised
Inventor: ZHENG ZHONGLI
IPC: C07D271/10
Filed: 1997-07-24
Abstract: In the present invention, there are disclosed IIb/IIIa inhibitors of the general formula II, in which X comprises a IIb/IIIa specificity determinant which does not impart significant VLA-4 activity and is selected from the group defined in the patent claims and Y represents a peptoid of the general formula PB1 or PB2 wherein the symbols comprised in the formulae are as defined in the patent claims. There is also disclosed a process for preparing the above-indicated cell adhesion inhibitors, said process comprising preparation of VLA-4 inhibitor containing VLA-4 specificity determinant and an integrin scaffold; and replacing said VLA-4 specificity determinant by the IIb/IIIa specificity determinant. These inhibitors and pharmaceutical compositions containing them are well suited for inhibition and prevention of cell adhesion and cell adhesion-mediated diseases.
Patent SK-287817-B6 (SK)
Title: Crystalline form of triazolo(4,5-d)pyrimidine compound, method for the preparation thereof, pharmaceutical composition containing thereof and its use
Inventor: BOHLIN MARTIN
IPC: A61P9/00
Filed: 2001-05-31
Abstract: A crystalline form of triazolo(4,5-d)pyrimidine compound of formula (I) being characterised by an X-ray powder diffraction pattern containing specific peaks defined in claims. Described is also a method for the preparation of the compounds, a pharmaceutical composition containing thereof and their use in the manufacture of a medicament in the prevention of arterial thrombotic complications in patients with coronary artery, cerebrovascular or peripheral vascular disease.
Patent SK-288669-B6 (SK)
Title: Reduction gear with movable member
Inventor: BALARA MILAN
IPC: F16H1/10
Filed: 2015-06-11
Abstract: Reduction gear with movable member consist of a fixed stator wheel (1) with internal teeth, surrounding the hobbing wheel (2) with external teeth. Into hobbing wheel (2) is inserted circular eccentric (3) and into it is fixed the input shaft (4) rotary bedded in the input bearing (5). To the hobbing wheel (2) is by means of front screws (6) coaxially fixed to the front flange (7). Through the front flange (7) goes the front rod (8) which is fixed to it by locking rings (9). To the front rod (8) is pushed moving member (10) through which goes rear rod (11) fixed by a locking rings (9) on the rear flange (12). Rear flange (12) is by rear screws (13) axially fixedly with the pressure wheel (14), spacer ring (15) and with the rear wheel (16) in which is fixed output shaft (17) rotary bedded in the output bearing (18).
Patent CU-23765-B7 (CU)
Title: Derivados de amina
Inventor: JONES LYN HOWARD
IPC: A61K31/18
Filed: 2008-09-18
Abstract: La invención se refiere a compuestos de la fórmula (I) ESPACIO PARA LA FÓRMULA y a procedimientos para la preparación, intermedios que se usan en la preparación, composiciones que contienen y usos de tales derivados. Los compuestos de acuerdo con la presente invención son útiles en numerosas enfermedades, trastornos y afecciones, en particular en enfermedades, trastornos y afecciones inflamatorios, alérgicos y respiratorios.
Patent CH-704359-B8 (CH)
Title: Composition nutritionnelle et flacon à 2 compartiments isolés contenant une telle composition.
Inventor: FAUVE DOMINIQUE
IPC: A61K35/748
Filed: 2011-10-14
Abstract: On décrit une Composition nutritionnelle, en flacon à 2 compartiments isolés (isolant une partie pulvérulente dans le compartiment «bouchon» et un liquide dans le flacon), permettant la préparation extemporanée d’une solution, destinée à améliorer les défenses naturelles de l’organisme. Cette composition permet de remédier aux principaux inconvénients présentés par les compositions nutritionnelles connues, à savoir une efficacité limitée du fait d’une faible biodisponibilité. Une telle composition peut prendre en poids: de 30.0 à 50.0% de dérivé liposoluble de spiruline, de 2.0 à 5.0% d’un composé contenant du sélénium, de 25.0 à 35% d’extrait d’acérola titré en vitamine C, le tout étant soluble dans un dérivé hydrosoluble de spiruline.
Patent EP-1161196-B8 (EP)
Inventor: GALLICCHIO ANTONIO
IPC: A61C8/00
Filed: 2000-01-27
Granted: 2005-09-21
Abstract: An implant for artificial teeth, including: an intrabony insert or implant (1) which is designed to be inserted in a fixed manner in the jawbone and is provided with a cavity (10); an artificial tooth assembly with a tooth stump (3) for the respective artificial tooth and a stem to be inserted and fixed in the cavity of the intrabony insert or implant; the cavity (10) of the intrabony implant has an undercut annular recess (12) below and above which there are hole portions (11,13,14) having a smaller diameter, one (11) of the hole portions, above the recess (12), being interrupted by at least one longitudinal access slot (121) for the passage of at least one lug of the stem of the tooth stump (3) by axial sliding and subsequent rotation, the outer upper end of the intrabony implant being polygonal, the tooth stump (3) protruding beyond the lug with a polygonal region for the insertion of a polygonal annular bush for the mutual locking of the stump (3) with respect to the intrabony implant (1) so as to prevent rotation.
Patent EP-1478238-B8 (EP)
Inventor: FLOETER ECKHARD
IPC: A23D9/00
Filed: 2003-02-03
Granted: 2007-11-07
Abstract: Triglyceride fat which comprises HUU triglycerides and at least 18 wt. % of HOH and HLH triglycerides, while the ratio HOH:HLH is in the range 30/70 to 85/15, which fat is characterized in that the fat contains at least 20 wt. % of HUU and 8-30 wt. % of SOO triglycerides, where O denotes the residue of oleic acid, S of stearic acid, L of linoleic acid, U of oleic acid or linoleic acid and H denotes the residue of a saturated fatty acid with more than 15 carbon atoms with the proviso that at least 50 wt. % of the saturated fatty acids in HOH, HLH and HUU are stearic acid. The fat is obtained preferably by blending two natural high stearic fats.
Patent EP-0648228-B8 (EP)
Inventor: HALL CHRISTIAN
IPC: C07K16/00
Filed: 1993-06-02
Granted: 2004-04-21
Abstract: PCT No. PCT/GB93/01173 Sec. 371 Date Nov. 21, 1994 Sec. 102(e) Date Nov. 21, 1994 PCT Filed Jun. 2, 1993 PCT Pub. No. WO93/24531 PCT Pub. Date Dec. 9, 1993The present invention provides antibodies for use in a method of immunoassay being antibodies specific to the polypeptide consisting of amino acids 1-76 (SEQ ID NO:1) of N-terminal brain natriuretic factor BNP(1-76). Also provided are methods and kits for the diagnosis or prognosis of conditions in which BNP(1-76) is a diagnostic or prognostic indicator, such as heart failure or hypervolemia.
Patent BR-PI0204599-B8 (BR)
Title: kit para a detecção simultânea de anticorpo para hcv e antígeno de hcv
Inventor: CHANDER BAHL
IPC: G01N33/576
Filed: 2002-11-05
Abstract: "seqüências de proteína de núcleo de hcv". a presente invenção descreve peptídeos e proteínas recombinantes que contém a seqüência da proteína do núcleo do vírus da hepatite c em que um ou mais dos aminoácidos foram modificados ou eliminados para remover a capacidade de estas proteínas se ligarem a anticorpos monoclonais murinos anti-hcv específicos. as eliminações e modificações são projetadas para manter a capacidade de esta proteína ser usada em imuno-ensaios usados para a detecção de anticorpos anti-hcv em indivíduos infectados com hcv.
Patent BR-PI0416779-B8 (BR)
Inventor: FLORENCE NICOLAS
IPC: A61K38/21
Filed: 2004-11-19
Abstract: A liquid pharmaceutical formulation (I) for prolonged release of active agent(s) (A) comprises a low viscosity aqueous colloidal suspension of submicron particles of water-soluble, biodegradable polymers (II) carrying hydrophobic groups, non-covalently associated with (A), where on parenteral injection (I) forms a gelled depot for prolonging the duration of (A) release to more than 24 hours. A liquid pharmaceutical formulation (I) for prolonged release of active agent(s) (A) comprises a low viscosity aqueous colloidal suspension (with water as dispersion medium) based on submicron particles (SMP's) of water-soluble, biodegradable polymers (II) carrying hydrophobic groups (HG's), non-covalently associated with (A). On parenteral injection, (I) forms a gelled depot in vivo (at least partially due to physiological proteins), controlling and prolonging the duration of (A) release to more than 24 hours. (I) is liquid under the injection conditions; at physiological temperature and/or pH; and/or in presence of physiological electrolytes at physiological concentrations and/or surfactant(s). Independent claims are included for: (1) a variant of (I) as described above, where the duration of release of (A) is not restricted but the concentration of (II) is sufficiently high to form a gelled depot in vivo in presence of protein(s) after parenteral injection; (2) novel derived products (preferably in powder or gel form), consisting of SMP's formed by non-covalent association of (II) and (A) as above and obtained from (I); and (3) methods of preparation of (I).
Patent BR-PI0507714-B8 (BR)
Title: contador de dose para uso com um dispensador de medicamento, e, dispensador de medicamento
Inventor: STEPHEN EDWARD AUGUSTYN
IPC: G06M3/12
Filed: 2005-02-15
Abstract: contador de dose para uso com um dispensador de medicamento, dispensador de medicamento, e, roda de contagem para um contador de dose é fornecido um contador de dose (1) para uso com um dispensador de medicamento. o contador de dose compreende uma primeira roda de contagem (20) arranjada para girar em torno de um primeiro eixo de rotação, a primeira roda de contagem incluindo um conjunto de dentes de acionamento primário (24) arranjado anularmente sobre a mesma para a rotação acionável da primeira roda de contagem em torno do primeiro eixo de rotação; uma segunda roda de contagem (30) arranjada para girar em torno do primeiro eixo de rotação, a segunda roda de contagem incluindo um conjunto de dentes de acionamento secundários (34) arranjado anularmente sobre a mesma; e uma roda de lançamento (40) arranjada para girar em torno de um segundo eixo de rotação deslocado pelo primeiro eixo de rotação, a roda de lançamento incluindo um conjunto de dentes de lançamento (44) arranjado anularmente sobre a mesma e em relacionamento engrenado com o conjunto de dentes de acionamento secundários da segunda roda de contagem tal que o movimento rotativo da roda de lançamento resulta em movimento da segunda roda de contagem. a primeira roda de contagem além disso inclui um dente de indexação fixo (28) arranjado para encaixe intermitente com os dentes de lançamento da roda de lançamento tal que o movimento rotativo da roda de lançamento resulta do movimento rotativo da primeira roda de contagem apenas quando o encaixe intermitente ocorre.
Patent BR-PI0518658-B8 (BR)
Inventor: ARMIN BAERTSCHI
IPC: A46B9/04
Filed: 2005-12-21
Abstract: An oral care implement with a handle includes a head with a tissue cleanser. The tissue cleanser may be a pad composed of an elastomeric material. The pad is disposed on the head on a surface opposite the tooth cleaning elements. The tissue cleanser may include a plurality of nubs extending for cleaning between the papillae of the tongue. The tissue cleanser may include a plurality of conically shaped nubs. A tissue cleanser can be used to reduce oral malodor problems and remove oral epithelial cells.
Patent BR-PI0804807-B8 (BR)
Inventor: CHRISTOPHE DUPAS
IPC: F16D51/18
Filed: 2008-11-06
Abstract: The shoe (4) has a rigid web (16) provided with an interior edge, and a cylindrical part (8) receiving a friction lining (12), where the interior edge includes a cut-out (90) providing access to an end terminal (66) that hooks a brake cable (64). The cut-out includes a depth extending on half of a width of the rigid web, and includes a length equal to the depth of the cut-out. The cut-out includes flanks inclined such that an inlet of the cut-out is larger than bottom of the cut-out, where the cut-out is placed near an end of the shoe.
Patent BR-PI1005301-B8 (BR)
Title: dispositivo de limpeza de ferimentos
Inventor: JOHANNES ENGL
IPC: A61F13/36
Filed: 2010-01-26
Abstract: dispositivo de limpeza de ferimentos, uso de fibras sintéticas para a fabricação de um dispositivo de limpeza de ferimentos, arranjo de embalagem e método para fabricação de um dispositivo de limpeza de ferimentos. um dispositivo de limpeza de ferimentos, que compreende ou é um lenço de limpeza de ferimentos (1), compreendendo pelo menos uma camada de suporte (2) e fios (3) dispostos na camada de suporte (2) e que saem para fora do suporte (2), preferivelmente feitos exclusivamente de fibras sintéticas, preferencialmente de fibras plásticas.
Patent BR-PI1007379-B8 (BR)
Title: composições farmacêuticas para o tratamento ou prevenção de infecções orais por e. coli
Inventor: JOAN M FALLON
IPC: C07K17/00
Filed: 2010-01-06
Abstract: composição farmacêutica, composição farmacêutica para uso no tratamento no prevenção de infecção por e. coli em um pássaro ou um mamífero, e método para reduzir a quantidade de e. coli presente em uma região da pele, tecido ou ferida em um mamífero ou ave. a presente invenção refere-se a composições e métodos para tratar a prevenir infecções de e. coli que são fornecidos. as composições podem ser formuladas como composições farmacêuticas ou como desinfetantes, sanitizadores, detergentes ou antissépticos, e podem ser usadas para erradicar ou reduzir as populações de e. coli desse modo tratar ou prevenir a infecção por e. coli. as composições incluem uma ou mais enzimas digestivas, por exemplo, uma ou mais protease, lipases, e amilases. métodos de usos das composições são também fornecidos.
Patent AU-2007352537-B8 (AU)
Title: Aluminum hydroxide
Inventor: HERBIET RENE GABRIEL ERICH
IPC: C01F7/023
Filed: 2007-06-21
Granted: 2013-05-09
Abstract: Aluminum hydroxide f lame-retardants and their use.
Patent AU-2017257185-B8 (AU)
Title: Phospholipase A2 inhibitors for immediate treatment of venom toxicity that causes hemolysis, cerebral edema, and acute kidney injury
Inventor: LEWIN MATTHEW R
IPC: A61K31/404
Filed: 2017-05-01
Granted: 2023-07-06
Abstract: Provided are methods for treatment of pathological conditions causing hemolysis, cerebral edema, acute kidney injury and non-anaphylactic shock, including envenomation, trauma, cerebral malaria and mast-cell diseases using at least one PLA2 inhibitor, alone or in combination with other agents. The unexpected versatility of PLA2 inhibitors, their dosage forms and combinations make them candidates as essential medicines for the developing world.
Patent BR-122015009396-B8 (BR)
Inventor: DAVID GREGORY AHERN
IPC: A61M15/00
Filed: 2004-10-18
Abstract: An inhaler (1) comprising a housing (2) to receive a blister (6a) having a puncturable lid (6c) and containing a dose of medicament for inhalation by a user is disclosed. It comprises a mouthpiece (5) through which a dose of medicament is inhaled by a user, a blister piercing member (7) comprising at least two discrete piercing heads (9) operable to pierce a corresponding number of holes in said blister, an actuator (3) comprising an arm pivotally mounted to the housing at one end, and an opening formed in the vicinity of each piercing head. At least one of said openings forms an airflow inlet into said blister and, at least one other of the openings forming an airflow outlet from said blister. The mouthpiece includes a primary chamber (31) having an outside air inlet (34) in communication, via the primary chamber, with the or each airflow inlet opening and, a secondary chamber (32) in communication with the or each airflow outlet opening. When a user inhales through the mouthpiece, air is drawn through the or each airflow inlet opening into the blister via the outside air inlet and the primary chamber to entrain the dose in the airflow, said entrained dose passing through the or each airflow outlet opening into the secondary chamber of the mouthpiece from where it is carried into the user's airway.
Patent CN-103092992-B8 (CN)
Title: 基于Key/Value型NoSQL数据库的矢量数据先序四叉树编码和索引方法
IPC: G06F17/30
Filed: 2013-02-17
Granted: 2016-09-14
Abstract: 本发明涉及一种基于Key/Value型NoSQL数据库的矢量数据先序四叉树编码和索引方法，这种方法使数据物理存储次序与空间范围连续性一致、数据主键次序与物理存储次序一致，从而在空间查询时能减少 I/O操作，提高查询效率。这种方法包括如下步骤：步骤1：完全四叉树空间划分与先序四叉树结点编码；步骤2：矢量数据前缀编码和索引构建；步骤3：先序四叉树索引。
Patent EP-1927815-B9 (EP)
Inventor: LOIDL MAX
IPC: F24V50/00
Filed: 2006-11-28
Granted: 2009-11-04
Abstract: The heat exchanger has multiple reinforcing grid bars (5) provided in combination with a very good heat conductive material of the heat exchanger, where the water of natural water body (9) flows on an outer side of the heat exchanger, and a medium provided in a heat exchanger circuit flows in an inner side of the heat exchanger or a cooling medium of a water pump system flows during a direct evaporation process. The combination of the reinforcing grid bars and the heat exchanger is applied in developed channels.
Patent AU-2016213923-B9 (AU)
Title: Helical hybrid stent
Inventor: RICHTER JACOB
IPC: A61F2/90
Filed: 2016-08-15
Granted: 2017-11-16
Abstract: An expandable helical stent is provided, wherein the stent may be formed of a main stent component and a securement. The main stent component is formed from a flat strip having one or more undulating side bands (401, 402) that may be connected to form geometrically shaped cells (430) and are helically wound to form a stent. The helical coils of the main stent component may be spaced apart or nestled to each other. The nestling of the undulation of adjacent helical windings contributes to maintaining the tubular shape and uniformity of the helically coiled stent. Alternatively, the flat strip may comprise a single undulating pattern. At the ends of the main stent component are end bands (407), which when wound, form a cylindrical ring. In one embodiment, one or more struts of the main stent component may have a width sufficient to include one or more fenestrations. The fenestrated struts may be connected by loops or turns wherein the material is narrower than that of the fenestrated struts to provide enhanced flexibility. The helical tubular is maintained with a securement. (Fig 1) ;To C;C L41r
Patent AU-2017218407-B9 (AU)
Title: Container with pressure accommodation panel
Inventor: Lohmeier Michael Andrew
IPC: B65D23/00
Filed: 2017-01-31
Granted: 2021-06-03
Abstract: A container is provided with a body portion. The body portion includes a first vacuum panel, a second vacuum panel, a third vacuum panel, a first diagonal column between the first vacuum panel and the second vacuum panel, and a second diagonal column between the second vacuum panel and the third vacuum panel. The second vacuum panel and the third vacuum panel are oriented in opposite directions. In response to a change in an internal container pressure, the body portion flexes at the first vacuum panel such that a surface of the first vacuum panel increases in concavity in response to an increasing pressure change.
Patent AU-2019200201-B9 (AU)
Title: Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
Inventor: SOLL MARK D
IPC: A61P33/00
Filed: 2019-01-11
Granted: 2021-02-18
Abstract: This invention relates to oral veterinary compositions for combating ectoparasites and 
endoparasites in animals, comprising at least one systemically-acting isoxazoline 
compound with a pharmaceutically acceptable carrier, and further provides methods for 
eradicating, controlling, and preventing parasite infections and infestations in an animal 
with same.
Patent DE-102017002606-B9 (DE)
Title: Störungserfassungsvorrichtung für Spritzgießmaschinen
Inventor: MARUYAMA JUNPEI
IPC: B29C45/76
Filed: 2017-03-17
Granted: 2020-12-17
Abstract: Störungserfassungsvorrichtung (1) für eine Spritzgießmaschine, wobei die Störungserfassungsvorrichtung (1) umfasst:eine Servo-CPU (10);eine Antriebseinheit, die einen Servomotor (13) auf der Basis einer Anweisung von der Servo-CPU (10) zum Antreiben eines beweglichen Teils antreibt und steuert;eine Einheit zum Erfassen von physikalischen Größen (100), die eine auf den Servomotor (13) einwirkende Last, eine Drehzahl des Servomotors (13), einen in den Servomotor (13) fließenden Strom oder eine Positionsabweichung des Servomotors (13) als eine physikalische Größe erfasst; underste und zweite Speichereinheiten (110, 130), welche die physikalische Größe derart speichern, dass die physikalische Größe mit der während des Betriebs des beweglichen Teils verstrichenen Zeit oder der Position des beweglichen Teils im Betrieb des beweglichen Teils als eine physikalische Referenzgröße verknüpft wird, wobeidie Störungserfassungsvorrichtung (1) nacheinander die physikalischen Referenzgrößen, die jeweils in der ersten und zweiten Speichereinheit (110, 130) gespeichert sind, mit einer physikalischen Größe, die aktuell erfasst wird, auf eine Weise sequenziell mit einer momentan erfassten physikalischen Referenzgröße derart vergleicht, dass die physikalischen Referenzgrößen und die momentan erfassten physikalischen Größen der während des Betriebs des beweglichen Teils verstrichenen Zeit oder der Position des beweglichen Teils im Betrieb des beweglichen Teils zugeordnet werden, und derart, dass erste und zweite Abweichungen von den physikalischen Größen aufgefunden werden, sodass eine Anomalie in dem Fall erfasst werden kann, wenn eine Abweichung der physikalischen Größen, einen Schwellenwert überschreitet,die erste Speichereinheit (110) direkt von der Servo-CPU (10) gelesen/beschrieben werden kann,die zweite Speichereinheit (130) nicht direkt von der Servo-CPU (10) gelesen/beschrieben werden kann, unddie Servo-CPU (10) eine Anweisung zum Stoppen oder Verzögern des beweglichen Teils in dem Fall ausgibt, wenn eine erste Abweichung einer physikalischen Größe, die eine Abweichung zwischen einer von der ersten Speichereinheit (110) gelesenen physikalischen Referenzgröße und einer aktuellen physikalischen Größe ist, oder eine zweite Abweichung einer physikalischen Größe, die eine Abweichung zwischen einer von der zweiten Speichereinheit (130) gelesenen physikalischen Referenzgröße und einer aktuellen physikalischen Größe ist, einen Schwellenwert überschreitet.