baber/WOPTO huggingface dataset:
Patent MX-7378-E (MX)
Inventor: CASANOVA MARIA JOSE VERDE
IPC: A61P9/00
Filed: 1985-03-26
Abstract: 1,4-Dihydropyridine derivs. of formula (I) and their acid addn. salts are new. R = OH, 1-4C opt. branched alkoxy which may be substd., such as methoxy or methoxymethoxy, or 2 gps. R on adjacent atoms form an alkylenedioxy gp., such as methylenedioxy or ethylenedioxy n = 1,2 or 3 R1 and R2 = 1-4C opt. branched alkyl which may be substd., such as methyl, ethyl, propyl, isopropyl, butyl, isobutyl, methoxyethyl or 2-pyridylmethyl. -
Patent PT-1218611-E (PT)
Inventor: KUMMERFELDT HENNING
IPC: E05B83/10
Filed: 2000-09-01
Abstract: A door block (9) serving for blocking a door (2), which is side-hinged on a casing (3) around an opening in a container wall, against being opened by unauthorized persons. The door block comprises a rotatable closing rod (5), a handle (6) on the closing rod and a cam (7) fitted on the closing rod for engaging a keeper (8) on the casing when the door is closed and the closing rod rotated into closed position by means of the handle. The door block furthermore comprises a, seen in cross section, mainly U-shaped covering (14) having a body (16) and two flaps (17) projecting from this body, and in the blocking position extending across the closing rod with a piece of this rod located in flushing cuts (18) in the flaps and the handle encompassed between the body and the flaps; a catch hook (19) pivotally mounted in the covering for locking the closing rod in the cuts of the flaps by means of a projection (26) on the catch hook; and a lock (13) for locking the catch hook in its locking position. The door block has a simple and effective structure. It is easy to apply as it does not require any use of tools nor any kind of manipulation in the structure of the respective door. It is furthermore difficult to break open, and a possible burglary is clearly revealed by the condition in which the door block will be left by the burglary.
Patent PT-1247032-E (PT)
Inventor: BERRY THOMAS E
IPC: F16J15/32
Filed: 2000-12-19
Abstract: A tank piston is shown with an improved seal and wiper. The piston is used in conjunction with tanks used for transporting semi-solid and viscous materials such as grease, oil, ink, and the like. The improved seal consists of an annular rubber member with a hollow chamber filled with an open cell foam material such as polyurethane, or a gel such as silica gel. The material in the chamber is compressible and expandable to provide a seal about the piston. Optionally, the piston is provided with an annular wiper structure that extends about the outer forward periphery of the piston, and is forwardly angled at about 45° relative to an axis of the piston. The wiper has a beveled end that makes contact with the interior surface of the tank to provide a cleaning action. A complementary second wiper may be added near the outer rearward periphery of the piston. A preferred embodiment is also shown that uses a tiered support assembly.
Patent PT-1216806-E (PT)
Title: Method and apparatus for the creation of a tool
Inventor: MARK MANUEL
IPC: G05B19/4099
Filed: 2001-12-20
Abstract: An apparatus 10 and a method 50 for the creation of a tool 40. The apparatus 10 and the method 50 allow for dynamic measurement of the tool 40 as it is being created and further allows for the use of positive feedback to increase the likelihood that the produced tool will be structurally similar to a certain model. The apparatus 10 and method 50 further allow sections of varying thicknesses to be used and provide a technique to create surfaces which further increase the likelihood that the produced tool will be structurally equivalent to a desired and modeled tool. <IMAGE>
Patent PT-1318569-E (PT)
Inventor: HAMELIN PATRICE
IPC: H01R13/453
Filed: 2002-12-04
Abstract: The current socket has a cap (110) with a front wall (112) and two holes. There is an obscurer above the contact elements moving between open and closed positions. The obscurer has two inclined surfaces (131A,131B) positioned facing the holes. There is a drive pin (117) acting on the obscurer faces (134,134A) allowing the obscurer to open. The drive pin forms a single block with the cap.
Patent PT-1406610-E (PT)
Inventor: SUNDERMANN BERND
IPC: A61K31/4709
Filed: 2002-07-03
Abstract: The invention relates to the use of substituted gamma-lactone compounds in the production of medicines for treating migraines, septic shock, neurodegenerative diseases, such as multiple sclerosis, Parkinsons, Alzheimers or Huntingtons disease, inflammations and related pain, cerebral ischaemia, diabetes, meningitis, arteriosclerosis, cancer, mycosis, or for healing wounds.
Patent PT-1560482-E (PT)
Title: Handle
Inventor: KUHN GUNTHER
IPC: B25G1/10
Filed: 2003-08-25
Abstract: According to an exemplary embodiment of the invention, a grip is provided for fastening different objects that can be attached to fingers, hands, arms or legs or other anatomical parts of a user. This grip prevents tools from slipping away or falling down. Objects do not need to be put away and a user, nevertheless, has a full freedom of movement in order to be able to perform different types of work such as cutting, tying, etc. more quickly than in the past. The grip may comprise a handle, a fixation element and a pulling element all of which being joint to one another in a fixed, gradual or continuous manner.
Patent PT-1610850-E (PT)
Title: Aerosolization apparatus with air inlet shield
Inventor: SHIRGAONKAR SAMEER
IPC: B05D7/14
Filed: 2004-04-09
Abstract: An aerosolization apparatus comprises a housing defining a chamber having a plurality of air inlets. The chamber contains an aerosolizable pharmaceutical formulation or is sized to receive a receptacle which contains an aerosolizable pharmaceutical formulation. A shield covers at least one of the air inlets or a portion of at least one of the air inlets. The shield prevents blockage of the air inlet by a user grasping the apparatus and inadvertently covering the air inlet. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the receptacle.
Patent PT-1733988-E (PT)
Title: Process and apparatus for the production of newspapers
Inventor: FRANZ HUNKELER
IPC: B65H45/28
Filed: 2005-06-16
Abstract: The method involves laying out sheets on top of each other in a collecting station (8) and folding booklets in a transverse folding station. The sheets are connected with each other and the booklets are stuck into one another in another collecting station. Side edge and longitudinal cutting, folding, booklet and the latter collecting stations are deactivated based on format and/or composition of a newspaper in case-by-case manner. An independent claim is also included for a device for execution of a method of producing a newspaper.
Patent PT-1757333-E (PT)
Title: Device for smothering a fire in a building
Inventor: REINA JOSE ANTONIO HERNANDEZ
IPC: A62C19/00
Filed: 2005-12-16
Abstract: Device to extinguish a fire produced in a building,  characterized by  having a bomb comprising a hollow body whose inner part carries a load of a fire-retarding component and an actuator that, when it hits the surface of the building, activates a detonator that makes the charge explode, scattering the fire-retarding component over the whole surface area of the radius of action, the detonator and explosive charge contained inside a receptacle and the detonator being connected by means of an electrical wire to one or various actuators installed on the surface of the body of the bomb.
Patent PT-2142570-E (PT)
Title: Anti-epcam antibody and uses thereof
Inventor: SANTIS RITA DE
IPC: A61K39/395
Filed: 2008-04-02
Abstract: An anti-EpCAM antibody, designated ST3232/10, of marine origin exhibits properties suitable for both therapeutic and diagnostic applications. It shows high affinity for the native antigen and good tumor selectivity.
Patent PT-828480-E (PT)
Inventor: SCHEIWE MAX WERNER
IPC: A61K9/50
Filed: 1996-05-24
Abstract: PCT No. PCT/CH96/00203 Sec. 371 Date Jan. 9, 1998 Sec. 102(e) Date Jan. 9, 1998 PCT Filed May 24, 1996 PCT Pub. No. WO96/37195 PCT Pub. Date Nov. 28, 1996A pharmaceutical pellet formulation having a core containing omeprazole as an active ingredient, and also having an outer, enteric coating encasing the core. Titanium dioxide is added to the core, and optionally, to the enteric coating in order to retard decomposition of the omeprazole resulting from the action of penetrating moisture and solvents, thus greatly improving the storage stability of the omeprazole formulation.
Patent PT-842430-E (PT)
Inventor: BURKE RAE LYN
IPC: C12Q1/70
Filed: 1996-06-20
Abstract: Novel methods and immunodiagnostic test kits for diagnosing herpes simplex virus (HSV) infection are disclosed. The methods and kits employ both type-specific and type-common antigens, in a single-step assay format, to provide for highly accurate results. The methods discriminate between HSV-1 and HSV-2 infection so that an accurate diagnosis can be performed.
Patent PT-868474-E (PT)
Inventor: DALBE BERNARD
IPC: C08K3/36
Filed: 1996-12-20
Abstract: The polyorganosiloxane composition resulting in a silicone elastomer of high thermal conductivity, which can reach and even exceed 1.2 W/m.K, the elastomer retaining an elongation at break of greater than 30%, comprises at least one functional polyorganosiloxane which crosslinks by a polyaddition or polycondensation reaction or by the radical route, optionally a polyorganohydrosiloxane, a catalyst, optionally a reinforcing filler and a filler intended to increase the thermal conductivity which is present in the composition in the proportion of 35 to 70% by volume with respect to the total composition, this filler comprising at least two groups of particles of very different mean diameters, a first group having a mean particle diameter of between 10 and 40 mm, present in a predominant amount in the filler, and a second group having a mean particle diameter of less than 5 mm.
Patent PT-1007533-E (PT)
Inventor: GRISSOM CHARLES B
IPC: C07F15/06
Filed: 1997-08-22
Abstract: The present invention relates to bioconjugates and the delivery of bioactive agents which are preferably targeted for site-specific release in cells, tissues or organs. More particularly, this invention relates to bioconjugates which comprise a bioactive agent and an organocobalt complex. The bioactive agent is covalently bonded directly or indirectly to the cobalt atom of the organocobalt complex. The bioactive agent is released from the bioconjugate by the cleavage of the covalent bond between the bioactive agent and the cobalt atom in the organocobalt complex. The cleavage may occur as a result of normal displacement by cellular nucleophiles or enzymatic action, but is preferably caused to occur selectively as a predetermined release site by application of an external signal. The external signal may be light or photoexcitation, i.e. photolysis, or it may be ultrasound, i.e. sonolysis. Further, if the photolysis takes place in the presence of a magnetic field surrounding the release site, the release of the bioactive agent into surrounding healthy tissue is minimized.
Patent PT-968341-E (PT)
Inventor: SCHWORER ARTUR
IPC: E04G1/15
Filed: 1998-03-18
Abstract: The invention relates to a dismountable scaffolding with vertical struts and horizontal struts. A base plate extends between said struts and is provided with hook-shaped end fittings on each front face. Said base plate can be placed on a rail section in such a way that vertical locking or unlocking can be selectably achieved by sliding the end fitting in the direction of the rail section. Horizontal antislip locking is achieved and cancelled by raising the end fitting, thereby preventing said fitting from sliding into an inactive vertical locking position when it is in an active vertical position.
Patent PT-988301-E (PT)
Inventor: LINDSAY BAMBOROUGH PAUL
IPC: C07D233/54
Filed: 1998-06-12
Abstract: Compounds of the following backbone structure: which are useful as Tumor necrosis factor (TNF) inhibitors in treating disease related to elevated TNF.
Patent PT-1003580-E (PT)
Inventor: MARSHALL JEREMY
IPC: A61M5/20
Filed: 1998-08-20
Abstract: An injection device is disposable, and is designed to have a reusable firing mechanism fitted to its rear end. A syringe carrier within the barrel of the device is initially locked in a position with the needle of the syringe retracted by a locking element inserted laterally through the barrel. This element also holds an axially movable connector to which the firing mechanism connects. The device is made operable by removal of the locking element, and after use a return spring ensures that neither the syringe carrier nor the connector assume positions where the locking element can be reinserted. An adaptor may be provided to facilitate preparing a syringe with a two-component dose, and for disposal after use the adaptor with an empty vial still attached can be fitted to the rear end of the injection device in place of the firing mechanism.
Patent PT-1002122-E (PT)
Inventor: ROBINS KAREN TRACEY
IPC: C12P13/02
Filed: 1998-07-22
Abstract: Microorganisms of species Amycolatopsis or Actinomadura able to convert nitriles into amides and provide enzyme extracts, are new. Also claimed are: (1) microorganisms of the species Rhodococcus GF270 (DSM 12211) and GF376 (DSM 12175), their variants and their mutants and their enzyme extracts, capable of converting nitriles into amides; (2) an enzyme with nitrile hydratase-activity obtained from the microorganisms above.
Patent PT-1032447-E (PT)
Inventor: BOUGAMONT JEAN-LOUIS
IPC: B65D47/34
Filed: 1998-11-25
Abstract: The invention relates to an endpiece for dispensing and/or measuring out liquid pharmaceutical substances, the endpiece comprising a cylindro-conical body (1) fitted with a bottom base (13) for receiving thrust and for coupling to a tank capable of being put under pressure, and an axial ejection duct (10) containing a central core (2) and communicating firstly at its top end with a spray nozzle, and secondly at its bottom end with the tank, it is characterized in that the top end of the ejection duct (10) is closed in temporary and leakproof manner by a wall (111) which is secured to the top portion (1a) of the body (1) and which extends perpendicularly to the duct, the wall being movable in reversible manner under drive from the substance, said wall being provided with a central orifice (110) capable of being closed in the closed position by a stud (20) secured to the core (2) being forced thereagainst, the periphery of the wall being attached to said body (1) via an elastically deformable link element (112) enabling the wall (111) to move in axial translation under pressure.
Patent PT-1098885-E (PT)
Inventor: TADASHI TERASAKA
IPC: C07D233/90
Filed: 1999-07-22
Abstract: Imidazole compounds having adenosine deaminase inhibitory activity represented by formula (I) wherein R1 is hydrogen, hydroxy, protected hydroxy, or aryl optionally substituted with suitable substituent(s); R2 is hydrogen or lower alkyl; R3 is hydroxy or protected hydroxy; R4 is cyano, (hydroxy)iminoamino(lower)alkyl, carboxy, protected carboxy, heterocyclic group optionally substituted with amino, or carbamoyl optionally substituted with suitable substituent(s); and -A- is -Q- or -O-Q-, wherein Q is single bond or lower alkylene, provided that when R2 is lower alkyl, then R1 is hydroxy, protected hydroxy, or aryl optionally substituted with suitable substituent(s), its prodrug, or their salt. The compounds are useful for treating and/or preventing diseases for which adenosine is effective.
Patent PT-1102719-E (PT)
Inventor: GRITTMANN GUNTER
IPC: B67D3/04
Filed: 1999-07-19
Abstract: Disclosed is a stowable spigot for beverage cans that comprises an outer sleeve with an arrester mechanism for insertion into the opening of a can. The outer sleeve comprises a sliding inner sleeve that supports a gripping member located outside the can. A plug formed at the inner end of the sleeve is sealed with a protection cap located on the outer sleeve. Once the outer sleeve is removed, the protection cap uncovers a channel formed therein. The inner sleeve further includes a push-valve having a drain hole associated therewith. The sleeves are interconnected through a cam and through a curvilinear slot for driving the inner sleeve towards the outside upon rotation of the gripping member. The outer sleeve comprises a draw hole which is located below and is closed by an insert. The draw hold is located adjacent to the abutment, while the insert can be ejected by the cam.
Patent PT-1114281-E (PT)
Inventor: DAVIDSON PAUL
IPC: F24D19/02
Filed: 1999-09-17
Abstract: A radiator support plug comprises a first portion (16, 33) adapted to be removably inserted into a fluid flow connection (35) of a radiator. A second portion (18, 37) of the plug is adapted to co-operate with a radiator supporting arrangement. The first portion may be inserted into and removed from the fluid flow connection of the radiator by means of a push fit.
Patent PT-1137445-E (PT)
Inventor: LUCAS JAMES
IPC: C02F1/72
Filed: 1999-11-23
Abstract: There is described a steriliser comprising an ultraviolet lamp, a microwave energy source for exciting said ultraviolet lamp and an enclosure for enclosing the ultraviolet lamp, the enclosure comprising a UV transparent waveguide. The steriliser is particularly suitable for use in the purification of water.
Patent IE-34863-L (IE)
Title: Epoxidizing olefins with hydroperoxides.
IPC: C07D301/19
Filed: 1971-01-07
Abstract: 1276637 Oxirane compounds SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ NV 7 Jan 1971 [9 Jan 1970] 824/71 Heading C2C The invention comprises a process for reacting one or more olefinic compounds with one or more hydroperoxide compounds to form one or more oxirane compounds in the presence of, as catalyst, an organotin compound.
[GB1276637A]
Patent IE-830293-L (IE)
Title: Pyrimidones and intermediates.
IPC: C07D317/00
Filed: 1983-02-14
Abstract: NEW MATERIAL:A compound shown by the formulaI(R<1> is H, lower alkyl, aralkyl, etc.; R<2> is lower alkyl; m and n are 1-3). EXAMPLE:2-[2-[[[2-[( Diaminomethylene )amino]-4-thiazolyl]methyl] thio]ethyl]-6-methylpyrimidine-4-one. USE:A suppressive agent for the secretion of acid in the stomach and an antiphlogistic. PROCESS:For example, an amidine derivative {e.g., 3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]propionamidine hydrochloride, etc.]} shown by the formula II is reacted with an acylacetic acid ester derivative (e.g., ethyl acetoacetate, etc.) shown by the formula III (R<5> is lower alkyl-, and, if necessary, in the presence of a base such as sodium methoxide, etc.
[JP58140088A]
Patent IE-43655-L (IE)
Title: Topical anti-inflammatory steroidal composition
IPC: A61K47/10
Filed: 1976-02-19
Abstract: This invention relates to a topical, anti-inflammatory, pharmaceutical composition which comprises (a) a pharmaceutically acceptable solvent, e.g. propylene glycol and water, and (b) at least two corticosteroids chosen from those represented by formulas A through K defined hereinafter, each corticosteroid dissolved in said solvent at a concentration equal to the saturation solubility for each steroid. Other suitable pharmaceutical formulation additives may be added to prepare the desired type of formulation, e.g. cream, ointment, lotion, or gel. The invention includes a process for preparing the compositions and a method for treating inflamed skin conditions using the novel compositions.
[US3934013A]
Patent IE-36231-L (IE)
Title: Triazolo diazepines
IPC: C07D405/04
Filed: 1972-03-28
Abstract: Title cpds. of formula (I): (where R1 is H or 1-3C alkyl; R2 is 1-4C alkyl or R2--R2 is a satd. divalent 2-5C aliphatic hydrocarbon residue, and rings A and B can be substd. by F, Cl, Br, CF3, NO2 or 1-6C alkyl or alkoxy) and their 5-oxides and acid addn. salts, can be used as tranquillisers, sedatives, muscle relaxants and anti-epileptics; the 5-oxides are also of use as inters. for further pharmacologically active cpds. Cpds. (I) are e.g. prepd. by (a) reacting a 2-X-3-R1-5-phenyl-3H-1,4-benzodiazepine (where X is SH, lower alkoxy or alkylthio opt. activated by a substituent, or opt. mono- or disubstd. amino) with (R2O)2CHCONHNH2. The 5-oxides are obtd. by oxidn.
[CH545302A]
Patent IE-44704-L (IE)
Title: ß-LACTAM ANTIBIOTIC
IPC: A61P31/04
Filed: 1977-02-25
Abstract: An aqueous solution of a salt of clavulanic acid with the exception of the calcium salt is treated with a cation exchanger resin in the form of the calcium salt. The calcium diclavulanate which is formed is eluted from the exchanger resin, resulting in a solution of calcium diclavulanate which is virtually free of cations other than calcium ions. Calcium diclavulanate dihydrate is allowed to crystallise out of the resulting solution and is isolated in crystalline form. The resulting salt is suitable as active component in pharmaceutical compositions, especially for oral administration.
[GB1561395A]
Patent IE-44721-L (IE)
Title: Acetohydroxamic acid derivatives
IPC: C07D223/22
Filed: 1977-03-15
Abstract: The invention provides new acetohydroxamic acid derivatives, having interesting properties on the central nervous system, of the formula: R1R2R3C-CO-NHOH, in which R2 and R3 are each hydrogen or C1-6 alkyl, and R1 is C1-6 alkyl Z1Z2 N (where Z1 and Z2 are each phenyl, substituted phenyl, or cycloalkyl), substituted hydantoinyl, benzhydroxylcarboxamido, Z3CH2- (where Z3 = optionally substituted aryl), Z4-A- (where Z4 is optionally substituted phenyl or naphthyl, and A is -NH-, -N(C1-4 alkyl)-, -N(C5-6 cycloalkyl)-, -NHCO-, -N(C1-4 alkyl)CO-, -N(C5-6 cycloalkyl)CO-, -CONH-, -CON(C1-4 alkyl)-, -CON(C5-6 cycloalkyl)-, -NHCONH-, -N(C5H6)CONH-, or -N(substituted phenyl)CONH-, optionally substituted benzimidazolyl, or an optionally substituted tricyclic radical, and their metal and acid addition salts.
[US4122186A]
Patent IE-33116-L (IE)
Title: Pyrryl-phenyl alkanoic acids
IPC: C07D207/327
Filed: 1969-04-28
Abstract: 1,264,367. 4 - [p - (1 - Pyrryl) phenyl] butyric and 3 - [p - (1 - pyrryl) benzoyl] propionic acids. J. R. GEIGY A.G. 28 April, 1969 [29 April, 1968; 20 Nov., 1968], No. 21523/69. Heading C2C. The invention comprises compounds of formula wherein Z is CH 2 or CO and R 1 is H, F or Cl, and their pharmaceutically acceptable salts. These compounds may be prepared by (1) reacting succinaldehyde or its derivative with a p-aminophenylbutyric or p-aminobenzoylpropionic acid; (2) decarboxylating the corresponding malonic acid; (3) hydrolysing the corresponding nitrile, alkyl ester or imido-ether; (4) reacting an alkyl 2 - acetyl - 4 - [p - (1 - pyrryl) phenyl] butyrate with alkali metal hydroxide (for Z = CH 2 ); (5) reducing the compound where Z = CO to that where Z = CH 2 . Details are given for the preparation of the following starting materials and intermediates: 4 - (4 - acetamino - 3 - chlorophenyl) butyric acid; ethyl 3-(p-aminophenyl) propionate; RCO 2 Et, RCH 2 OH, RCH 2 Cl, RCH 2 OTs-(p), RCH(CO 2 Et) 2 and BCH(CO 2 H) 2 [where R = p - (1 - pyrryl) phenethyl]; and R<SP>1</SP>CH(CO 2 Et) 2 , R<SP>1</SP>CH(CO 2 H) 2 and R<SP>1</SP>CH 2 CO 2 Et [where R<SP>1</SP>= 3 - chloro - 4 - (1 - pyrryl) phenethyl]. Also prepared is the 2,4-dinitrophenylhydrazone of 3-[p-(1-pyrryl) benzoyl] propionic acid. Therapeutic compositions for oral, rectal, local or parenteral administration comprise compounds of the above general formula, which have analgesic, antiphlogistic and antipyretic activity.
[GB1264367A]