baber/WOPTO huggingface dataset:
Patent CA-2467552-A1 (CA)
Inventor: FLOHR ALEXANDER
IPC: A61P25/14
Filed: 2002-11-11
Abstract: L'invention concerne des composés de formule générale (I) dans laquelle R?1¿ représente un phényle, une piperidine-1-yle ou une morpholinyle; A désigne -O- et R désigne-(CH¿2?)¿n?-N(R")-C(O)-alykle inférieur, -(CH¿2?)¿n?-O-alkyle inférieur, -(CH¿2?)¿n?-O-(CH¿2?)¿n?-O-alkyle inférieur, un alykle inférieur, -(CH¿2?)¿n?-morpholinyle, -(CH¿2?)¿n?-phényle,-(CH¿2?)¿n?-N(R")¿2?, (CH¿2?)¿n?-pyridinyle, -(CH¿2?)¿n?-CF¿3?, (CH¿2?)¿n?-2-oxo-pyrrolidinyle ou un cycloalkyle en C¿4-6?; R" représente de manière indépendante un hydrogène ou un alkyle inférieur et n est égal à 1 ou 2; ou A désigne -N(R')-et R représente un alykle inférieur, un cycloalykle en C¿4-6?, -(CH¿2?)¿n?-O-alykle inférieur, -(CH¿2?)¿n?-pyridinyle, -(CH¿2?)¿n?-piperidinyle, -(CH¿2?)¿n?-phényle, (CH¿2?)¿n?-N(R")-C(O)-alykle inférieur, -(CH¿2?)¿n?-morpholinyle ou (CH¿2?)¿n?-N(R")¿2?; R' et R" représentent de manière indépendante un hydrogène ou un alkyle inférieur et n est égal à 1 ou 2; ou A représente -CH¿2-? et R représente -N(R")-(CH¿2?)¿m?-O-alykle inférieur, -N(R")¿2? S-alykle inférieur ou une acétidinyle, une pyrrolidinyle ou une piperidinyle, éventuellement substituée par un hydroxy ou un alcoxy inférieur ou représente un morpholinyle, -N(R")-CH¿2?)¿m?-C¿4-6-?cycloalkyle, -N(R")-(CH¿2m?-C(O)O-alkyle inférieur, -N(R")-(CH¿2?)¿m?-C(O)OH, -2-oxo pyrrolidinyle, -N(R")-C(O)O-alkyle inférieur, -O(CH¿2?)¿m?-O-alkyle inférieur ou alcoxy; R" représente de manière indépendante un hydrogène ou un alkyle inférieur et m est égal à 1, 2 ou 3; A désigne S- et R représente un alkyle inférieur; ou A-R représentent ensemble une piperazinyle, substituée par un alkyle inférieur, -C(O)-alkyle inférieur ou un groupe oxo ou représentent une piperdinyle substituée par un alcoxy inférieur ou un hydroxy ou représentent une morpholinyle, substituée par un alkyle inférieur ou un cycloalkyle en C¿4-6?, -azétidine-1-yle, éventuellement substituée par un hydroxy ou un alcoxy inférieur, une thiomorpholine-1,1-dioxo, un -tétrahydopyrane ou un 2-oxa-5-aza-bicyclo[2.2.1]hept-5-yl. L'invention concerne également des sels d'addition acide acceptables sur le plan pharmaceutique desdits composés qui sont des ligands du récepteur de l'adénosine. Plus précisément, les composés selon l'invention présentent une bonne affinité au récepteur A¿2A-? et sont utiles, par conséquent, dans le traitement de maladies relatives à ce récepteur.
Patent CA-2468130-A1 (CA)
Title: Surgical stapling instrument having a firing lockout for an unclosed anvil
Inventor: SHELTON FREDERICK E IV
IPC: A61B17/072
Filed: 2004-05-20
Abstract: A surgical instrument for laparoscopic and endoscopic clinical procedures simultaneously severs and staples tissue clamped in an end effector comprising an elongate channel, which holds a staple cartridge, and a pivotally attached anvil. An E-beam firing bar engages the channel and selectively engages the anvil during distal firing movements, wherein the tissue is severed and stapled driven upward from the staple cartridge to form against the anvil. In particular an upper pin of the firing bar is disengaged from the anvil before firing. A ramped transition from an anvil to an anvil slot avoids misfiring when the end effector has clamped too much tissue, yet assists in successfully clamping a slightly excess amount of tissue.
Patent CA-2468982-A1 (CA)
Title: Dietary modifications to improve fertility
Inventor: VAN DER LENDE TETTE
IPC: A23K20/147
Filed: 2002-07-18
Abstract: The invention relates to products and methods for increasing the productivity in farming by improving the fertility of healthy farming mammals. More in particular, the invention relates to products and methods for improving the fertility of animals by reducing placental insufficiency. According to the invention, this is obtained by providing a product which is enriched in L- arginine. The arginine products of the invention may be applied to improve fertility, which may be used in improving the yield in viable offspring of an animal livestock.
Patent CA-2470558-A1 (CA)
Title: Device for producing filaments
Inventor: BAUMEISTER MICHAEL
IPC: B29C48/30
Filed: 2004-06-09
Abstract: The invention pertains to a device for producing filaments, in particular, from a thermoplastic polymer, wherein the filaments emerge from the spinneret openings of a spinneret plate. A distribution device is provided for distributing the molten polymer being supplied over a preliminary spinning width. At least one exchangeable distribution plate with several distribution openings that are distributed over the spinning width is arranged downstream of the distribution device. The exchangeable spinneret plate is arranged downstream of the distribution plate, wherein said spinneret plate contains spinneret channels that are distributed over the final spinning width. The spinning width defined by the distribution openings is smaller or larger than the preliminary spinning width, and the preliminary spinning width can be reduced or enlarged to the final spinning width with the aid of the distribution plate. The desired final spinning width can be adjusted by exchanging the distribution plate.
Patent CA-2473843-A1 (CA)
Title: Hair extension applicator
Inventor: GOLD DAVID ANTHONY
IPC: A41G3/00
Filed: 2003-01-23
Abstract: A hair extension applicator, of the kind used to lengthen and/or thicken head hairs by applying additional hair extensions to natural hair, enables a strong precision and rapidity in use and comprises a handle, a pair of jaws adjacent therebetween, supported on said handle, apt to receive therebetween a portion of head hair and one or more fixing elements of respective additional hair extensions, pressing member and respective actuation means which determine the programmed translation of the pressing member with respect to a contrast means.
Patent CA-2475003-A1 (CA)
Title: Double-stranded oligonucleotides
Inventor: WIEDERHOLT KRISTIN A
IPC: A61P17/06
Filed: 2003-02-03
Abstract: Antisense sequences, including duplex RNAi compositions, which possess improved properties over those taught in the prior art are disclosed. The invention provides optimized antisense oligomer compositions and method for making and using the both in in vitro systems and therapeutically. The invention also provides methods of making and using the improved antisense oligomer compositions.
Patent CA-2475288-A1 (CA)
Inventor: DEZAWA MARI
IPC: C12N5/0793
Filed: 2003-02-06
Abstract: It is intended to provide a method of differentiating/inducing bone marrow interstitial cells into nerve cells and skeleton muscle cells by transferrin g a Notch gene. Namely, a method of differentiating/inducing bone marrow interstitial cells into nerve cells or skeleton muscle cells in vitro which comprises transferring a Notch gene and/or a Notch signaling-associated gene into the above cells, wherein the differentiated/induced cells finally produced are obtained as the results of the cell division of the bone marrow interstitial cells having the Notch gene and/or the Notch signaling-associat ed gene transferred thereinto. It is also intended to provide a method of furth er differentiating/inducing the differentiated/induced cells as described above into dopaminergic neurons and acetylcholinergic neurons. Moreover, it is intended to provide a method of treating a nerurodegenerative or myodegenerative disease using the nerve precursor cells, nerve cells or skeleton muscle cells produced by the above methods.
Patent CA-2476862-A1 (CA)
Inventor: LAWHORN RICHARD LOWELL JR
IPC: G06Q40/00
Filed: 2003-01-15
Abstract: In a system for recognizing revenue for the sale of services, where the amount of revenue recognized is based upon the use of the services and upon events that can occur before the services are used that can potentially affect the amount of revenue recognized for the sale, a master ticket record processor (20) can receive and process information related to an event, which is associated with a sale of services and which occurs at some time after the sale. A business-related processor (40) can perform additional business-related processing of the event information to derive a business result that can supplement the event information. The master ticket record processor (20) can then store both the business result and the event information related to a sale in a storage device.
Patent CA-2479002-A1 (CA)
Inventor: PARKOS MARIA P
IPC: G07B17/00
Filed: 2003-02-27
Abstract: Cette invention a trait à une machine de traitement du courrier (10) dont la capacité est optimisée par réduction du délai nécessaire au système de sécurité postale pour produire la signature numérique et la marque d'affranchissement pour chaque objet postal. Cette machine de traitement du courrier (10) est pourvue d'une imprimante (16), conçue pour imprimer des marques d'affranchissement sur les objets postaux. Cette imprimante (16) est couplée à un processeur (12) commandant le fonctionnement de la machine (10).
Patent CA-2480015-A1 (CA)
Title: Trigger mechanism for small firearms
Inventor: THOMELE ADRIAN
IPC: F41A19/48
Filed: 2003-12-19
Abstract: The invention relates to a trigger mechanism for small firearms with a striking hammer (1), a trigger (2), and a trigger rail (3), which interacts with this trigger and which can be moved by a control element from an engagement position for cocking the striking hammer (1) into a release position for releasing the cocked striking hammer (1). According to the invention, the control element is a control slide (19), which can be moved by the movement of an action (11) during repetition of the small firearm and through which the trigger rail (3) can be moved from its release position into a catch position for catching the striking hammer (1) cocked during repetition.
Patent CA-2480595-A1 (CA)
Title: Zinc citrate beads in oral compositions
Inventor: RYLES CHRISTINE WATSON
IPC: A61K8/365
Filed: 2003-04-23
Abstract: An oral product, particularly for anti-tartar use, is provided which include s from about 0.001 to about 20%of beads which include zinc salt, the zinc salt having a weight average particle size ranging from 0.01 to 5mm, and a dental base.
Patent CA-2481402-A1 (CA)
Inventor: MICINSKI EDWARD
IPC: A23L27/00
Filed: 2003-03-06
Abstract: This invention relates to processes for purifying sucralose by the use of an initial non-crystallization purification procedure followed by three or more sequential crystallization steps and recycle of the mother liquor remaining from each crystallization step to the feed of another crystallization or purification step. This invention also relates to sucralose compositions as well as compositions comprising the sucralose compositions of the present invention. These compositions may be highly pure and have a superior taste profile.
Patent CA-2481607-A1 (CA)
Inventor: BAUER WILLIAM
IPC: A61B17/10
Filed: 2002-06-18
Abstract: L'invention concerne un dispositif (10) d'agrafage mécanique servant à fixer un tissu profond durant la fermeture de la face péritonéale d'une plaie de coupure associée à un processus chirurgical laparoscopique. La présente invention porte également sur une agrafe (72) unique destinée à être utilisée avec le dispositif (10) d'agrafage de l'invention. Ladite invention concerne aussi un procédé d'utilisation de l'agrafe (72) et du dispositif (10) d'agrafage.
Patent CA-2485170-A1 (CA)
Title: Monitoring the state of a communications network
Inventor: ORMSHAW IAN JOHN
IPC: H04L12/26
Filed: 2003-04-29
Abstract: The invention provides an interface element (1) adapted to interface with a communications network (7), the element comprising monitor means (4) to monitor the state of the network, and a method of using the interface element.  The monitor means may monitor the state of the network by monitoring the state of a link or component of the network, by receiving one or more messages regarding the state of the link/component. The monitor means may monitor the state of the network by registering any changes in the state of the network or by registering any faults occurring in the network. The monitor means may communicate the state of the network to one or more components of the network.  The interface element may react to the state/changes in the state of the network. The monitor means may comprise a router (4), running routing protocol software with which the network can communicate, e.g. the Open Shortest Path First routing protocol. The interface element may comprise a host, such as a residential gateway programmable device. The communications network may be a packet-switched internet protocol based network and may carry telephony-type information and data information.
Patent CA-2486050-A1 (CA)
Title: Brake drum stacking method and brake drum with drum stacking structure
Inventor: BROTHERTON JOSEPH A
IPC: B65B35/50
Filed: 2004-10-26
Abstract: Brake drums are described with a stacking structure which allows the brake drums to be stacked directly on top of one another. Desirably, some nesting of the brake drums occurs during this stacking. A method of stacking brake drums for storage and shipment is also described.
Patent CA-2487634-A1 (CA)
Title: Emergency unlocking device for locking and unlocking systems for swinging sliding doors, in particular of rail vehicles
Inventor: FRONZ REINHARD
IPC: E05B83/08
Filed: 2004-11-12
Abstract: The invention relates to an emergency unlocking device for locking and unlocking systems for swinging sliding doors, in particular of rail vehicles. Taking the disadvantages of the known prior art as a starting point, a simple and cost-effective emergency unlocking means is to be provided which is distinguished by a high level of reliability. As a solution, an emergency unlocking device is proposed which is composed of a traction means 32 which engages on a lever system, wherein the traction means 32 engages on a first spring-loaded pivoted lever 33 which is connected via a second lever 34 to a third lever 36. The third lever 36 is attached to the axial shaft 36a of a spring-loaded rotary magnet 37 and has elongate holes 36c in which a bolt 35 is displaceably mounted. When the traction means 32 is subjected to tensile stress, the bolt 35 engages with a fourth lever 21 which is pivotably mounted on a shaft 22, and moves said fourth lever 21. The fourth lever 21 is operatively connected via at least one horizontally arranged coupling rod 24, 25 and deflection unit to a locking rod which can be moved in the vertical direction. A rod 20 via which a force component which brings about the locking and unlocking of the door leaves can be applied engages on the fourth lever 21.
Patent CA-2488662-A1 (CA)
Inventor: EDWARDS DANIEL P
IPC: F16D43/04
Filed: 2004-11-30
Abstract: A centrifugal clutch for coupling the rotational force of a driving member to a driven member includes a hub that is adapted to be secured at substantially its center to the driving member. The hub has a plurality of arms extending substantially radially from its center. A plurality of clutch shoe means for coupling the driving and driven members are located circumferentially about the center of the hub and are slidably mounted on the arms of the hub for movement independently of one another along the arms inwardly and outwardly of the center of the hub.  The clutch includes means for limiting the furthest extent to which the clutch shoe means may move outwardly of the center of the hub along the arms of the hub and means for urging the clutch shoe means inwardly along the arms of the hub toward the center of the hub.
Patent CA-2492314-A1 (CA)
Inventor: SEPEHRI NARIMAN
IPC: A61B19/00
Filed: 2005-01-13
Abstract: A compact four degrees of freedom parallel mechanism suitable for use as a hand control or wrist is provided that has backdrivability, is singularity free and has a large workspace and a large force reflecting capability. The structure is light but rigid, and the electric actuators are all placed on the ground or base and provide independent control of each degree of freedom. Each degree of freedom is connected to an actuator either directly or through a cable drive system. The first two degrees of freedom are created by two identical pantographs pivoted together on pivoted joints to define a hemispherical motion of an object (end point) about a center point (hemisphere center). The third and fourth degrees of freedom represent rotation and sliding motions of the object around and along the radius of the created hemisphere, respectively. The axes of these latter degrees of freedom are concentric, and these axes intersect with the axis of the pantographs pivoted joints at the hemispheric center.
Patent CA-2492543-A1 (CA)
Title: Monitoring signal-to-noise ratio in x-ray diffraction data
Inventor: WANG BI-CHENG
IPC: G01N23/207
Filed: 2003-07-14
Abstract: The present invention relates to methods of diffractometrically determining the structures of materials by characterizing their electron density distributions (figure 2). More particularly, the present invention relates t o methods of collecting, processing and interpreting X-ray diffraction data, which allow real time evaluation of the signal-to-noise ratio in crystal diffraction experiments (figure 1A-1D). The present methods related to the derivation of statistical indices for monitoring and evaluating signal-to- noise ratios in diffraction experiments. In addition, the present invention provides methods of determining the electron density distributions of crysta ls using anomalous scattering signals corrected for noise. Further, the present invention provides methods of increasing the signal-to-noise ratios in X-ray diffraction data.
Patent CA-2495173-A1 (CA)
Title: Crucible cover for aluminothermic reaction
Inventor: DELCROIX FREDERIC
IPC: E01B11/52
Filed: 2003-08-12
Abstract: The invention relates to a cover (3) for closing an upper aperture (17) of the reaction chamber (15) of the crucible (2). The inventive cover (3) is substantially continuous and solidly provided with a solid annular filter seal (35) arranged between a lower peripheral bearing edge (29) and an upper peripheral edge (11) of the crucible (2). Said filter seal is embodied in such a way that it is used as a solid intermediate element for applying the lower edge (29) to the upper board (11). Said invention can be used, for example for aluminothermic welding, in particular in a tunnel or underground.
Patent CA-2497590-A1 (CA)
Title: Ink-jet printing apparatus and ink cartridge therefor
Inventor: USUI MINORU
IPC: D06M13/44
Filed: 1999-05-18
Abstract: An ink jet type printing apparatus in which an ink supply needle is located near one side in a direction perpendicular to the reciprocated directions of a carriage, a circuit board is mounted on a wall of an ink cartridge in the vicinity of the side on which an ink supply port is formed and plural contacts for connecting to external control means are formed on the exposed surface of the circuit board.
Patent CA-2502592-A1 (CA)
Title: Method for producing cathode material for secondary battery and secondary battery
Inventor: HATTA NAOKI
IPC: C01B25/37
Filed: 2003-10-17
Abstract: A method for producing a cathode material for a secondary battery, characterized in that it comprises admixing a compound liberating a phosphate ion in a solution (phosphoric acid H3PO4, phosphorus pentoxide PO5, ammonium dihydrogenphosphate NH4H2PO4 and the like), water and metallic iron, adding lithium carbonate, lithium hydroxide or a hydrate thereof to the resultant mixture, and firing the resultant reaction product , to thereby synthesize LiFePO4.
Patent CA-2504393-A1 (CA)
Inventor: RISSLING MURRY J
IPC: F17D5/00
Filed: 2005-04-12
Abstract: A probe for pipelines includes a hammer member with an upper hammer and a hollow lower sleeve; a probe member with an upper head slidably engagable in the sleeve of the hammer member, and a lower driven portion having a rounded bottom end. A  tether is attached to the probe member and to the hammer member such that the head can slide in and out of the sleeve within a movement range, bat is prevented from moving out of engagement with the sleeve. In operation the hammer member can be lifted and accelerated down onto the probe member to drive the driven portion of the probe member into the ground to locate a buried pipeline, and can be dropped and accelerated up against the tether to pull the driven portion out of the ground. A splash guard and stake hole maker are also provided.
Patent CA-2507053-A1 (CA)
Title: Method of operating a fuel cell power system to deliver constant power
Inventor: SIMPSON TODD A
IPC: H01M8/04
Filed: 2003-11-27
Abstract: The present invention relates to a fuel cell system and a method of operatin g same, The fuel cell has a first reactant inlet, a first reactant outlet, a second reactant inlet, a second reactant outlet. The invention involves (a) providing a first reactant incoming stream to the first reactant inlet; (b) providing a second reactant incoming stream to the second reactant inlet; (c ) monitoring a fuel cell state variable indicative of flooding; (d) based on t he fuel cell state variable, determining whether the fuel cell is flooded; and, (e) providing an additional amount of the first reactant to the fuel cell wh en the fuel cell is flooded.
Patent CA-2507193-A1 (CA)
Inventor: MARKS GREGORY ALAN
IPC: G06F3/0482
Filed: 2004-07-30
Abstract: A system and related methods permit a group of two or more users to initiate a realtime message session online, and invite participants to transmit and share digital images and other media to a common viewer tool seen by all . The messaging session may be conducted via a message server which mediat es the exchange of typed, spoken or other messages back and forth amongst participants. One or more users may assume control of the commonly displayed images, for instance in a slideshow or other viewer tool. Users can discuss the displayed images or other media in realtime. The participants may each view, save, store, print or otherwise use or manipulate the copy of the image or images as presented to them. Session control of the set of displayed images may be passed from one user to another on a voluntary basis, using for example a control token or other mechanism. In embodiments shared control may be used. Out-of-order rendering and other optimizations may enhance the response time to participating viewers.
Patent CA-2507496-A1 (CA)
Title: Determinants moleculaires de maladie osseuse de type myelome et utilisations de ceux-ci
Inventor: SHAUGHNESSY JOHN D
IPC: C12Q1/68
Filed: 2003-12-04
Abstract: Afin d'identifier des déterminants moléculaires de maladie osseuse lytique dans un myélome multiple, les profils d'expression d'environ 12000 gènes dans des cellules plasmatiques enrichies en CD 138 provenant de patients souffrant de myélome multiple récemment diagnostiqués ne présentant pas d'évidence radiologique de lésions lytiques (n = 28) ont été comparés à ceux présentant = 3 lésions lytiques (n = 47). Deux protéines sécrétées de type <=soluble frizzled related protein 3>= (SFRP-3/FRZB), antagonistes de la voie de signalisation WNT et l'homologue humain de la protéine Dickkopf-1 (DKK1), ont été exprimés chez 10 sur 47 présentant des lésions osseuses lytiques, mais seulement 16 sur 28 ne présentant pas de lésions osseuses(<I>P</I> < .05 ). Les protéines DKK1 et FRZB n'ont pas été exprimées dans des cellules plasmatiques provenant de 45 donneurs de moelle osseuse normale et chez 10 patients souffrant de macroglobulinémie de Waldenstrom, une tumeur maligne des cellules plasmatiques caractérisée par l'absence de lésion osseuse. Ces données indiquent que ces facteurs sont d'importants médiateurs de maladie osseuse de type myélome multiple, et que des inhibiteurs de ces protéines peuvent être utilisés pour entraver une maladie osseuse.