baber/WOPTO huggingface dataset:
Patent DE-69320030-D1 (DE)
Inventor: BOYD EDWARD ANDREW
IPC: C07D261/20
Filed: 1993-02-18
Granted: 1998-09-03
Abstract: Compounds of formula (I)    <IMAGE>  (I)  in which R1 represents hydrogen, a C1-6 aliphatic hydrocarbyl group or a C1-4 aliphatic hydrocarbyl group substituted by a C3-6 alicyclic hydrocarbyl group or by a phenyl group, which phenyl group is unsubstituted or substituted by a halogeno or C1-3 halogenoalkyl group, R2 represents hydrogen, R3 represents hydrogen, a 5- or 6-membered ring aromatic heterocyclyl group containing one or two heteroatoms selected from nitrogen, oxygen and sulphur which is unsubstituted or substituted by a halogeno or C1-3 halogenoalkyl group, or a group AR wherein A is a straight chain C1-4 aliphatic hydrocarbyl group terminally substituted by R which is hydrogen, a phenyl group or a 5- or 6-membered ring aromatic heterocyclyl group containing one or two heteroatoms selected from nitrogen, oxygen and sulphur, which phenyl or heterocyclyl group R is unsubstituted or substituted by a halogeno or C1-3 halogenoalkyl group, R4 and R5 each represent hydrogen or together represent an oxo group and R6, R7 and R8 each represent hydrogen, or R4 represents hydrogen and two of R5, R6, R7 and R8 together represent the second bond of a double bond joining positions 4 and 5, 5 and 6 or 6 and 7 with the remaining two of R5, R6, R7 and R8 representing hydrogen, the compound optionally being in the form of a salt thereof formed with a physiologically acceptable inorganic or organic acid, are of value for the treatment of anxiety and in the improvement of learning and/or the reversal of amnesia.
Patent DE-69326092-D1 (DE)
Inventor: LEWIS DAVID H
IPC: G01R33/30
Filed: 1993-03-25
Granted: 1999-09-30
Abstract: A spinning apparatus for conducting magnetic resonance spectroscopy on a sample, having: an inner holder for the sample; mechanism for spinning the inner holder, while positioned in a magnetic field, about its axis; and a substantially nonmagnetic mechanical first bearing for supporting the first end-portion of the inner holder. Also, a spinning apparatus having: an inner holder for the sample; mechanism for spinning the inner holder, while positioned in a magnetic field, about its axis; a first and second bearing for supporting, respectively, a first and second end-portion of the inner holder; an outer housing for retaining the inner holder; mechanism for spinning the outer housing about its axis; and a substantially nonmagnetic mechanical third bearing for supporting the right end-portion of the outer housing. Also included is a device for measuring the magnetic resonance spectrum of a sample. <IMAGE>
Patent DE-69422158-D1 (DE)
Inventor: M LOEY JON
IPC: G06F11/07
Filed: 1994-02-02
Granted: 2000-01-20
Abstract: For establishing two-way communication links between processes in a distributed operating system, the processes are provided with ports through which communication between the processes is performed. The processes and the ports make possible for the operating system to keep a check on processes having links and to use these links also if the process per se is terminated, and to discover an error in the process and terminate it. For enabling the operating system to be able to transmit via the links information regarding process or computer drop out and thus be able to propagate this information through the whole chain of linked processes, and to report this information to applications executed in the linked processes in order to enable these to undertake application specific measures, a code is used which is called at link abortion and communication errors. The function of this code includes terminating an erroneous process and reporting the error to an error handling code. The first mentioned code is always executing in a process to which an error has been reported.
Patent DE-69432087-D1 (DE)
Inventor: CAVALLA DAVID
IPC: A61K31/52
Filed: 1994-06-21
Granted: 2003-03-06
Abstract: Novel purine derivatives and their isoguanine and dithioxanthine precursor compounds are disclosed. These compounds have bronchial and tracheal relaxation and/or anti-inflammatory activity. The invention is also related to processes for their preparation, to pharmaceutical compositions containing them and to their medical use. In certain preferred embodiments, the invention relates to 3-substituted and 3,8-disubstituted 6-amino purine derivatives.
Patent DE-69502223-D1 (DE)
Inventor: DORAN THOMAS I
IPC: A61P3/02
Filed: 1995-02-27
Granted: 1998-06-04
Abstract: This invention is for 1α-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol, which can be further characterized by the formula:and which is useful as an agent for the treatment of sebaceous gland diseases such as acne and sebhorreic dermatitis. It can be prepared by removing the silyl protecting groups from a corresponding compound with silyl protected hydroxy groups.
Patent DE-69508582-D1 (DE)
Inventor: HARSLEY ANDREW
IPC: F16L11/14
Filed: 1995-06-23
Granted: 1999-04-29
Abstract: PCT No. PCT/GB95/01487 Sec. 371 Date Mar. 3, 1997 Sec. 102(e) Date Mar. 3, 1997 PCT Filed Jun. 23, 1995 PCT Pub. No. WO96/00176 PCT Pub. Date Jan. 4, 1996An integrally formed tie strip (10) is formed with a series of apertures (14), at respective locations that are spaced apart in succession along the strip, and is formed with a series of laterally projecting latch members (11), at respective locations that are spaced apart in succession along the strip, for resisting withdrawal from one of the said apertures after having been passed therethrough.
Patent DE-69517179-D1 (DE)
Inventor: EDWARDS RAYMOND
IPC: G01N33/68
Filed: 1995-07-26
Granted: 2000-06-29
Abstract: PCT No. PCT/GB95/01766 Sec. 371 Date Jan. 24, 1997 Sec. 102(e) Date Jan. 24, 1997 PCT Filed Jul. 26, 1995 PCT Pub. No. WO96/03657 PCT Pub. Date Feb. 8, 1996A solution phase assay of glycated proteins, such as glycated haemoglobin and plasma-soluble glycated proteins, is carried out by reacting the assay sample with a photoluminescent or chemiluminescent marker compound containing a boronic acid group which reacts selectively with the glycated protein. The luminescence of the marker compound is excited at a wavelength at which it is preferentially quenched by the binding of the marked compound to the glycated protein. The quenching in luminescence gives a measure of the degree of glycation of the glycated proteins.
Patent DE-69519579-D1 (DE)
Inventor: SIVIK ROBERT
IPC: D06M13/352
Filed: 1995-07-13
Granted: 2001-01-11
Abstract: The present invention relates to fabric care compositions to reduce the fading of fabrics from sunlight, comprising: (A) from about 1% to about 25% by weight of the composition of a non-fabric staining, light stable antioxidant compound, preferably containing at least one C8-C22 hydrocarbon fatty organic moiety; (B) from 3% to about 50% by weight of the composition of a fabric softening compound; (C) from about 25% to about 95% by weight of the composition of a carrier material; and (D) optionally, from about 0% to about 20% by weight of the composition of a non-fabric staining, light stable sunscreen compound, preferably containing at least one C8-C22 hydrocarbon fatty organic moiety; wherein the antioxidant compound is a solid material having a melting point of less than about 80 DEG  C. or is a liquid at a temperature of less than about 40 DEG C.; wherein the sunscreen compound absorbs light at a wavelength of from about 290 nm to about 450 nm; and wherein the sunscreen compound is a solid material having a melting point of from about 25 DEG  C. to about 90 DEG  C. or a viscous liquid at a temperature of less than about 40 DEG  C.
Patent DE-69519924-D1 (DE)
Inventor: SHOENFELD YEHUDA
IPC: A61K39/395
Filed: 1995-03-09
Granted: 2001-02-22
Abstract: This invention provides therapeutic methods for inhibiting tumor metastasis and for treating primary tumors. The methods of this invention do not cause serious side effects and will be effective for a broad spectrum of cancerous diseases. In particular, the invention discloses a novel method comprising administering to a mammal a preparation of intravenous immunoglobulin (IVIG). The IVIG preparation to be administered according to this invention may contain intact immunoglobulin molecules or fragments of immunoglobulins. The preparation is administered parenterally, preferably via intravenous, intracavitary or subcutaneous routes, either as a sole agent or in combination with other agents or methods which are commonly used for cancer treatment.
Patent DE-69523799-D1 (DE)
Inventor: NAKANISHI KEITA
IPC: F16D69/02
Filed: 1995-03-17
Granted: 2001-12-20
Abstract: A method for producing friction material free of pills having at least 2 mm in the shorter diameter comprising mixing a dispersion medium and a friction base containing carbon fibers having a weighted mean fiber length of at least 0.3 mm, a binder and a friction modifier to form a dispersion with a solid content concentration of 0.5 to 50 % by weight, filtering the dispersion, drying the filter cake and forming the cake. The friction material has a good coefficient of friction and is excellent in its heat resistance, wear resistance and reinforcement.
Patent DE-69524090-D1 (DE)
Inventor: IKENOYA TADAKATSU
IPC: B65D85/72
Filed: 1995-05-18
Granted: 2002-01-03
Abstract: A packaging container comprising a packaging material including a paper substrate (13), an intermediate layer, an outermost layer (15) and an innermost layer (14) and having opposite side edges which overlap each other so that the outermost layer and the innermost layer of the packaging material face each other. A bending portion (19) is interposed between the outermost layer (15) and the innermost layer (14) by folding the bending portion joined with these layers. The outermost layer and the intermediate layer are made of resins which have compatibility with each other. The bending portion is formed by projecting the intermediate layer and the innermost layer from one side edge of the paper substrate and the outermost layer. <IMAGE>
Patent DE-69527725-D1 (DE)
Inventor: FELT C
IPC: A61B17/17
Filed: 1995-05-04
Granted: 2002-09-12
Abstract: A system for resurfacing orthopedic joints by arthroscopic means. The system involves a method that includes the delivery of a curable biomaterial, and the use of minimally invasive means to prepare an injury site, and then deliver, cure and shape a curable biomaterial at the site of injury.
Patent DE-69528361-D1 (DE)
Inventor: DOAT BERNARD
IPC: A61K31/70
Filed: 1995-02-24
Granted: 2002-10-31
Abstract: PCT No. PCT/FR95/00219 Sec. 371 Date Feb. 4, 1997 Sec. 102(e) Date Feb. 4, 1997 PCT Filed Feb. 24, 1995 PCT Pub. No. WO95/22976 PCT Pub. Date Aug. 31, 1995Paraffin oil and lactulose-based jellied clear laxative emulsion containing from 75 to 85 parts by weight of liquid paraffin oil and from 25 to 15 parts by weight of an edulcorated lactulose aqueous solution. The invention also concerns a method for the preparation of said emulsion.
Patent DE-69529291-D1 (DE)
Inventor: ALACK S
IPC: B28C7/16
Filed: 1995-09-28
Granted: 2003-02-06
Abstract: A portable mixing module for preparing solutions and slurries from particulate solid material. The module comprises a portable frame, and an eductor-mixer mounted on and movable with the frame. The eductor-mixer has a first inlet for connection to a source of fluent particulate material, a second inlet for connection to a source of pressurized working fluid, and a discharge for discharging a mixture of the fluent particulate material and the working fluid at a first rate. A surge tank is mounted on and movable with the frame for receiving the mixture discharge from the eductor-mixer. A pump is mounted on and movable with the frame. It has an intake connected to the outlet of the surge tank and a discharge for connection to an outfeed line for delivery of mixture from the surge tank to a remote location. The pump is operable to pump mixture from the surge tank at a second flow rate not substantially less than the first flow rate.
Patent DE-69530727-D1 (DE)
Inventor: CAMPBELL SHANNON K
IPC: B65D35/22
Filed: 1995-07-24
Granted: 2003-06-18
Abstract: A two component desensitizing dentifrice composition is disclosed which comprises a first dentifrice component containing a desensitizing potassium salt such as potassium nitrate and a second dentifrice component containing a second desensitizing agent other than a potassium salt the such as SnF2, the second desensitizing agent being incompatible with the potassium salt, the first and second dentifrice components being maintained separate from the other until dispensed for application to teeth requiring relief from dentine hypersensitivity. <MATH>
Patent DE-69535539-D1 (DE)
Inventor: KORENBERG JULIE R
IPC: C12Q1/6841
Filed: 1995-05-09
Granted: 2007-08-30
Abstract: In accordance with the present invention, high resolution, rapid and reproducible chromosomal banding methods have been developed. Invention methods enable the accurate mapping of genes to single chromosome bands with no registration shift. In accordance with another embodiment of the present invention, DNA or cDNA probes uniquely identifying physical genomic locations are provided. Such reagents are useful for the identification of the chromosomal band from which a particular DNA sequence is derived.
Patent DE-69600837-D1 (DE)
Inventor: COTY ALAIN
IPC: A61F2/30
Filed: 1996-01-15
Granted: 1998-11-26
Abstract: PCT No. PCT/FR96/00065 Sec. 371 Date Jan. 26, 1998 Sec. 102(e) Date Jan. 26, 1998 PCT Filed Jan. 15, 1996 PCT Pub. No. WO96/25117 PCT Pub. Date Aug. 22, 1996A device for elongating long bones such as thigh bones, shin bones and arm bones, including an intramedullary nail with a tubular sleeve (4), and an extension (5) axially slidable within the sleeve (4). The sleeve and the extension include means (6; 7) for rigidly connecting them to two bone portions separated by an osteotomy, and means for moving the extension (5) relative to the sleeve (4), whereby both the intramedullary nail and the corresponding bone may gradually be elongated. The means for moving the extension (5) relative to the sleeve (4) include an electric motor (8) arranged within the sleeve (4) and linked to a speed reducer (9) driving a screw/nut assembly (13, 14, 15) for moving the extension (5) relative to the sleeve, and means (2) for supplying power to the electric motor (8) and automatically controlling the value and direction of the movement imparted to the extension (5) in the sleeve (4) by the screw/nut assembly (13, 14, 15) driven by the electric motor (8).
Patent DE-69607392-D1 (DE)
Inventor: GRIFFIN PETER
IPC: A61J1/00
Filed: 1996-11-14
Granted: 2000-04-27
Abstract: PCT No. PCT/GB96/02794 Sec. 371 Date Aug. 14, 1998 Sec. 102(e) Date Aug. 14, 1998 PCT Filed Nov. 14, 1996 PCT Pub. No. WO97/18991 PCT Pub. Date May 29, 1997A multi-compartment container is charged with a plurality of doses of powdered medicament so that the volume of each dose is than that of the respective compartments in which it is contained. A respective protuberance is inserted into each respective compartment, which is then filled with medicament and the protuberance is then removed. The container may take the form of an apertured plate, in which case the filling step can be achieved by placing the container on a porous bed and in communication with a reservoir of particulate material, and then passing gas through the reservoir, the apertures in the container and the bed. There is also shown apparatus for performing the method, the apparatus comprising a reservoir for the particulate material and a conduit for relaying particulate material from the reservoir to the compartments, the conduit including protuberances which are insertable into the compartments to reduce the available volume of the latter. The size of the doses can be controlled by appropriate selection of protuberance dimensions, and a plate-type container, when filled by the method, can be relatively easily sealed by, for example, the application of laminated foil.
Patent DE-69609928-D1 (DE)
Inventor: PERRON LOIC
IPC: E01B27/11
Filed: 1996-11-27
Granted: 2000-09-28
Abstract: The train has a series of trucks, including three with pallets of new sleepers. One is for removing old sleepers, and one with two conveyors for old and new sleepers. It has a system for lifting the old rails and depositing them on either side of the track. A lower conveyor (13) is used for removing old sleepers (4) and an upper conveyor (15) for delivering new ones. It has an excavator for lifting part of the old ballast, and a system (18) for laying the new rails on the new sleepers (3). The layer (16) for the new sleepers is situated behind the lower section of the ballast excavator, so that the new sleepers are positioned across the track and laid on a remaining bed of ballast. The new rails are then fixed to the sleepers and the excavated ballast is redistributed between them.
Patent DE-69612973-D1 (DE)
Inventor: FREEMAN CHARLES
IPC: G01N1/30
Filed: 1996-03-27
Granted: 2001-06-28
Abstract: A device for processing samples, particularly biological samples, comprising a support retaining member forming a substantially sealed support cell provided with a fluid inlet and a fluid outlet for the introduction and removal, respectively, of fluids used in processing a sample. In addition, an automated apparatus and method are used with the support cell for processing samples supported on solid supports.
Patent DE-69613798-D1 (DE)
Inventor: WASSERMAN ERIC PAUL
IPC: C08F4/602
Filed: 1996-11-27
Granted: 2001-08-16
Abstract: A catalyst composition comprising A) an aluminoxane-impregnated support prepared by contacting an aluminoxane with an inert carrier material and heating to a temperature of at least about 80 DEG  C; B) a metallocene of the formula: <MATH> wherein M is a metal from groups IIIB to VIII of the Periodic Table; each L and L' is independently a cycloalkadienyl group bonded to M; each Y is independently hydrogen, an aryl, alkyl, alkenyl, alkylaryl, or arylalkyl radical having 1-20 carbon atoms, a hydrocarboxy radical having from 1-20 carbon atoms, a halogen, RCO2-, or R2N-, wherein R is a hydrocarbyl group containing 1 to about 20 carbon atoms; n and m are each 0, 1, 2, 3, or 4; y is 0, 1, or 2; x is 1, 2, 3, or 4; and x-y ≥ 1; C) a bulky aluminum alkyl of the formula: <MATH> wherein R<1> is a hydrocarbyl group having 1 to 12 carbon atoms; x is an integer from 0 to 2; R<2> is a hydrocarbyl group of the formula -(CH2)y-R<3>, wherein y is an integer from 1 to 8; and R<3> is a saturated or unsaturated hydrocarbyl group having 3 to 12 carbon atoms containing at least one ring, and D) methylaluminoxane is provided. The catalyst composition may be used to prepare olefin polymers having increased short chain branching frequency.
Patent DE-69618630-D1 (DE)
Inventor: LISI J
IPC: C07K14/505
Filed: 1996-09-20
Granted: 2002-02-21
Abstract: The present invention is directed to an in vitro method of determining the in vivo EPO activity of a sample containing EPO. More particularly, the present method comprises treating a sample containing EPO under conditions which remove desialylated EPO, and measuring the in vitro EPO activity of the resulting treated sample. In a preferred embodiment, desialylated EPO is removed from the sample by incubating the sample with cells of the human hepatoma cell line HepG2, and in vitro EPO activity is determined by incubating the treated sample with cells of an EPO-responsive cell line and measuring the proliferation or viability of the EPO-responsive cells. The present invention is useful, for example, in quantitating the biologically active EPO in a variety of sample types.
Patent DE-69620890-D1 (DE)
Inventor: NEFTEL FREDERIC
IPC: A61M5/168
Filed: 1996-08-20
Granted: 2002-05-29
Abstract: PCT No. PCT/FR96/01297 Sec. 371 Date Feb. 24, 1998 Sec. 102(e) Date Feb. 24, 1998 PCT Filed Aug. 20, 1996 PCT Pub. No. WO97/07842 PCT Pub. Date Mar. 6, 1997The invention relates to injection apparatus that is capable of operating continuously. According to the invention, the apparatus comprises two independent injection bottles (12) of at least one liquid that is to be injected into a patient via a tube, each of the bottles including means (51) for detecting that injection of the liquid contained in the bottle has terminated, which means control means (53) for interrupting the flow of liquid. The apparatus comprises upstream injection apparatus (10) having two feeder tubes (50) connected to respective bottles (12), and downstream injection apparatus (70) with pump means (72, 84) for pumping the liquid and connected firstly to the patient via a downstream tube (78) and secondly to coupling means (54). An application is performing perfusion prior to radiological examination using an X-ray or an NMR scanner.
Patent DE-69628659-D1 (DE)
Inventor: MORRISSEY H
IPC: G01N33/86
Filed: 1996-11-22
Granted: 2003-07-17
Abstract: An assay has been developed to detect the presence of blood clotting factors, including factors VIII and IX, utilizing mutated tissue factor. Mutated forms of wild type tissue factor as well as various forms of truncated tissue factor can be used. Preferably, substitutions of glutamine, alanine, glutamic acid, or combinations thereof are made at amino acid positions 165, 166 or 165 and 166. Various tissue factor mutants exhibit different extents of activity in supporting FVIII and FIX activation: Q<165>Q<166> > A<165>A<166> > E<165>E<166>.
Patent DE-69633720-D1 (DE)
Inventor: AMEYE SERGE HECTOR
IPC: A23L25/00
Filed: 1996-08-02
Granted: 2004-12-02
Abstract: Process for preparation and pre-cooking of whole or milled grain comprises: (a) mixing grain with water; (b) acidifying to pH 4.5, and (c) cooking. Also claimed is a vacuum conditioning of grain which has been pre-soaked in salt water, softened by heating and acidified to pH 4.5.
Patent DE-69637631-D1 (DE)
Inventor: OKAZAKI TSUNEKO
IPC: C12N5/08
Filed: 1996-08-26
Granted: 2008-09-18
Abstract: A mammalian chromosome is produced according to the method comprising the steps of: 
introducing a DNA construct comprising a mammalian telomere and a centromere into a mammalian cell, wherein the centromere has a DNA sequence containing some copies of CENP-B box sequence consisting of: 
5'-NTTCGNNNNANNCGGGN-3'  
wherein N is any one of A, T, C and G.
Patent DE-69700359-D1 (DE)
Inventor: GANCEL ETIENNE
IPC: H01H71/16
Filed: 1997-04-09
Granted: 1999-09-02
Abstract: The bimetal blade (1) presents an axial groove (2) of rectangular shape and flanked by raised sides (3,4). The blade is made up of two identical blades joined together along a plane (5). The bimetal blade is linked to the connection terminal of a circuit breaker (D). A screw (14), accessed from outside the breaker box, can be used to adjust the blade.
Patent DE-69705297-D1 (DE)
Inventor: MANN STEPHEN PHILIP
IPC: A23K3/02
Filed: 1997-02-17
Granted: 2001-07-26
Abstract: The subject invention pertains to methods for treating silage which comprises adding to the silage a microorganism having the characteristic of Lactobacillus buchneri, NCIMB 40788, to produce a secondary metabolite as well as fatty acids normally produced in fermentation, and further comprising maintaining the silage closed for a period sufficient for the secondary metabolite to accumulate. This secondary metabolite has the ability to inhibit the growth of spoilage organisms including yeasts, molds and spore-forming bacteria.
Patent DE-69706661-D1 (DE)
Inventor: VARANASI PRABODH
IPC: C09K3/18
Filed: 1997-03-31
Granted: 2001-10-18
Abstract: A method is disclosed for imparting hydrophobicity to the surface of a substrate that is repeatedly treated with a solution containing a low level organofunctional silane. The method has particular application in toilet bowl dispensing systems, hard surface cleaners and for providing abrasion or scratch resistant coatings.