baber/WOPTO huggingface dataset:
Patent CA-3083176-A1 (CA)
Title: Treatment of tachycardia
Inventor: ARONSEN JAN MAGNUS
IPC: A61K31/44
Filed: 2018-11-23
Abstract: The invention provides compounds which are selective PDE2 inhibitors for use in the treatment of tachycardia or tachyarrhythmia. Such compounds are particularly suitable for use in the treatment of any of the following conditions: atrial tachycardia, atrial fibrillation, atrial flutter, paroxysmal supraventricular tachycardia, premature ventricular contractions (PVCs), ventricular fibrillation and ventricular tachycardia, and may be used alone or in combination therapy with other conventional cardiovascular drugs, e.g. beta-blockers. In particular, the invention provides compounds which are selective PDE2 inhibitors for use in the treatment of ventricular tachycardia in patients who are suffering from, or who are at risk of suffering from heart failure, CPVT or long QT syndrome.
Patent CA-3084966-A1 (CA)
Inventor: NORTHRUP CHARLES
IPC: G06N5/02
Filed: 2017-12-07
Abstract: A computer-implemented method is disclosed for a first (P(TM)) to gain knowledge,. The method includes: performing a first P(TM(i)) to interact with a P(TM(thing)) to set a first Thing that is representative of content, performing a second P(TM(i)) to interact with the P(TM(thing)) to parse the content of the first Thing as a second Thing that is representative of a statement, performing a third P(TM(i)) to interact with the P(TM(thing)) to evaluate the statement of the second Thing to compute a third Thing that is representative of a performable statement, and performing a fourth P(TM(i)) to interact with the P(TM(thing)) to perform the performable statement of the third Thing, The fourth P(TM(i)), in performing the performable statement, interacts with P(TM(thing)) to set one or more Things that are representative of posterior knowledge.
Patent CA-3089559-A1 (CA)
Title: Modulateurs des recepteurs nmda spiro-lactames et leurs utilisations
Inventor: KHAN M AMIN
IPC: A61K31/397
Filed: 2019-01-31
Abstract: L'invention concerne des composés doués de puissance dans la modulation de l'activité des récepteurs NMDA. De tels composés peuvent être utiles dans le traitement de pathologies telles que la dépression et des troubles associés ainsi que d'autres troubles.
Patent CA-3090857-A1 (CA)
Inventor: SCHICKER OWEN
IPC: E21B17/02
Filed: 2019-02-15
Abstract: The present invention relates to a wireline retrieval head assembly and downhole tool, the wireline retrieval head assembly for coupling to the downhole tool for installation in and retrieval from downhole in a mineral industry field of use, wherein a first of the wireline retrieval head assembly and downhole tool has a retention member that has or is configured to receive a pivot member and a second of the wireline retrieval head assembly and downhole tool has a complementary link with an opening for receiving the pivot member, such that the link can be coupled to the retention member to create a pivot coupling to allow for articulation between the wireline retrieval head assembly and the downhole tool during installation and retrieval of the downhole tool, and the link can be removed from the retention member to remove the downhole tool from the wireline retrieval head assembly.
Patent CA-3094249-A1 (CA)
Inventor: TAN PEARL LIN
IPC: G01N33/68
Filed: 2019-03-26
Abstract: A method for assessing the oxidation states of a protein in a sample, the method comprising the steps of contacting the sample with a first label adapted to selectively bind to at least one reduced cysteine group of the protein therein to form a first labelled sample; forming a sub-sample of the first labelled sample; treating the sub-sample to selectively reduce at least one reversibly oxidised cysteine group of the protein therein to form a treated sub-sample; contacting the treated sub-sample with a second label adapted to selectively bind to a reduced cysteine group of the protein to form a second labelled sample; and assessing the first and second labelled samples for a plurality of oxidation states of the protein.
Patent CA-3094337-A1 (CA)
Inventor: VO PETER H
IPC: F16F15/04
Filed: 2019-02-08
Abstract: An isolator device comprises a first mount coupleable to an input structure subject to shock and/or vibration energy, a second mount coupleable to an object to be isolated. A flexure structure coupled between the first and second mounts, and comprises a plurality of parallel flexures, a series of flexures, and a plurality of transition portions, all defining an isolation path between the first and second mounts. The parallel flexures are tuned to resonant frequency to attenuate shock and/or vibration in an axial direction relative to a normal axis. The series of radial flexures are tuned to resonant frequencies to attenuate shock and/or vibration energy in both radial directions relative to the normal axis. The isolator device can be a single piece of metallic material. An elastomeric damping material can be disposed within openings defined by the flexure structure to dampen response at the isolator's resonant frequency.
Patent CA-3094615-A1 (CA)
Title: Rolling seal for transfer of pressure in a downhole tool
Inventor: MACDONALD LORN SCOTT
IPC: F16J15/02
Filed: 2018-05-24
Abstract: This disclosure provides a completion tool that uses a rolling seal to actuate a flow valve or replace a piston in a down hole tool. The rolling seal is located in a fluid chamber of the completion tool and divides the fluid chamber into first and second smaller fluid chambers and fluidly seals the first smaller fluid chamber from the second smaller fluid chamber. The rolling seal responds to a fluid pressure within the fluid chamber that causes the closed end of the rolling seal to invert thereby transferring fluid pressure between the first and second fluid chambers, which actuates a flow valve actuation assembly.
Patent CA-3094963-A1 (CA)
Title: Hot surface igniters for cooktops
Inventor: SPROWL BRUCE C
IPC: F23Q7/22
Filed: 2019-03-27
Abstract: Hot surface igniter assemblies used in cooktops are shown and described. The hot surface igniters include a silicon nitride ceramic body with an embedded, resistive, heat- generating circuit. When energized, the circuit generates temperatures in excess of 2000°F in under 4 seconds to ignite cooking gas such as natural gas. To prevent damage to the igniter during use or cleaning, an insulator assembly is provided which protects the distal end of the igniter ceramic body from damage while still exposing it to the cooking gas flow from the burner. In addition, a number of different terminal connection schemes for connecting the igniters to a power source are shown and described.
Patent CA-3096031-A1 (CA)
Title: Method for manufacturing a railcar body
Inventor: LAFLAMME MARTIN
IPC: B61D17/08
Filed: 2020-10-13
Abstract: A method for manufacturing a railcar body comprises assembling an underframe assembly, side walls, a roof and end walls made from laser cut sheet and plate components where the assemblies made from sheet components are robotically laser welded by solely using melt-through welds and where the assemblies made from plate components are robotically laser welded using solely butt welds.
Patent CA-3098362-A1 (CA)
Title: Asymmetrical vacuum-insulated glazing unit
Inventor: BEN TRAD ABDERRAZEK
IPC: E06B3/66
Filed: 2019-05-13
Abstract: The present invention refers to a vacuum insulating glazing unit (10) extending along a plane, P, defined by a longitudinal axis, X, and a vertical axis, Z; having a width, W, measured along the longitudinal axis, X, and a length, L, measured along the vertical axis, Z. The length of the vacuum insulating glazing unit, L, is equal to or greater than 300 mm, (L = 300 mm). The vacuum insulating glazing unit comprises: a. a first glass pane (1) having a thickness Z1, and a second glass pane (2) having a thickness, Z2, wherein the thicknesses are measured in the direction normal to the pane, P. The thickness of the second glass pane, Z2, is equal to or greater than 3 mm, (Z2 = 3 mm). Z1 is greater thanZ2 so that a thickness ratio, Z1/Z2, of the thickness of the first glass pane, Z1, to the thickness of the second glass pane, Z2, is equal to or greater than 1.30 (Z1 / Z2 = 1.30), and greater than Z1 / (Z1  2.10) (Z1/Z2 > Z1 / (Z1  2.10)). The first glass pane and the second glass pane are float annealed glass panes and wherein the first glass pane has a coefficient of thermal expansion, CTE1, and the second glass pane has a coefficient of thermal expansion, CTE2, and wherein the absolute difference between CTE1 and CTE2 is at most 0.40 10-6/°C (¦CTE1-CTE2¦=0.40 10-6/°C). b. a set of discrete spacers (3) positioned between the first and second glass panes, maintaining a distance between the first and the second glass panes and forming an array having a pitch, ?. The pitch, ?, is comprised between 10 mm and 26 mm (10 mm = ? = 26 mm). c. a hermetically bonding seal (4) sealing the distance between the first and second glass panes over a perimeter thereof. d. an internal volume, V, defined by the first and second glass panes and the set of discrete spacers and closed by the hermetically bonding seal and wherein there is a vacuum of absolute pressure of less than 0.1 mbar.
Patent CA-3100581-A1 (CA)
Title: Construction genetique
Inventor: MCDONALD MICHAEL
IPC: C12N15/85
Filed: 2018-05-25
Abstract: Une construction génétique comprend un promoteur lié fonctionnellement à une première séquence de codage, qui code pour la tyrosine hydroxylase (TH), et une seconde séquence de codage, qui code pour la GTP cyclohydrolase 1 (GCH1), la seconde séquence de codage étant en 3' par rapport à la première séquence de codage, et les première et seconde séquences de codage faisant partie d'un seul opéron. La construction génétique ne code pas pour une acide aminé aromatique décarboxylase (AADC).
Patent CA-3102161-A1 (CA)
Inventor: AHRENS HARTMUT
IPC: C07D413/06
Filed: 2019-05-29
Abstract: L'invention concerne des phénylpyrimidines substituées représentées par la formule générale (I) et leurs sels (I) compatibles sur le plan agrochimique ainsi que leur utilisation dans le domaine de la protection phytosanitaire.
Patent CA-3102238-A1 (CA)
Title: Substrat non conducteur revetu d'une peinture a teneur reduite en oxyde de graphene et methodes de detection d'une fuite et d'une deformation
Inventor: ALVAREZ-ALVAREZ ABEL
IPC: E02D31/00
Filed: 2019-06-11
Abstract: La présente invention concerne un substrat non conducteur revêtu au moins partiellement d'une peinture comprenant de l'oxyde de graphène réduit et un polymère thermodurcissable, le substrat non conducteur étant directement revêtu par la peinture, un procédé de fabrication de ce substrat non conducteur revêtu, des procédés de détection de fuites ou de déformation de contrainte et les utilisations dudit substrat non conducteur revêtu.
Patent CA-3102588-A1 (CA)
Title: System for physical-mechanical recovery and refining of non-ferrous met als from electronic scrap
Inventor: JIMENEZ GUZMAN FRANCISCO JAVIER
IPC: B03B9/06
Filed: 2019-05-17
Abstract: The invention relates to a system for the recovery and refining in a physical-mechanical manner of non-ferrous metals from electronic scrap, comprising means for separating the metals of interest from the polymeric support frames and resins, which does not require the addition of solvents, nor an increase in temperature, for the breaking down and separation of the materials such that no waste is produced that is toxic for the environment.
Patent CA-3103899-A1 (CA)
Title: Miniaturized mobile, low cost optical coherence tomography system for home based ophthalmic applications
Inventor: OGGENFUSS CHRISTIAN
IPC: A61B3/10
Filed: 2019-06-20
Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.
Patent CA-3112344-A1 (CA)
Inventor: ROBERT REMY
IPC: C07K16/28
Filed: 2019-05-31
Abstract: The present application is directed to depleting antigen binding sites which bind to CXCR3, and a method of using these antigen binding sites to treat autoimmune and inflammatory conditions, in particular, fatty liver disease, the accumulation of lipid deposits in the liver, steatoheptatits, graft rejection and conditions associated with effector and/or memory T cells.
Patent CA-3114048-A1 (CA)
Title: Recreational inhalation device
Inventor: FOLMANN SIMON VILLUM
IPC: A24F1/16
Filed: 2019-06-27
Abstract: A recreational inhalation device (10) for a user to inhale smoke and/or vapour.The recreational inhalation device (10) comprises a device body (12) having an inlet (14) for receiving smoke and/or vapour, an outlet (16) for emitting smoke and/or vapour to the user. A passage (18) extends between the inlet (14) and the outlet (16) for conveying smoke and/or vapour from the inlet (14) to the outlet (16). A plurality of baffles at or adjacent to the passage (18) forms a tortuous pathway between the inlet (14) and outlet (16).
Patent CA-3115708-A1 (CA)
Inventor: HASHEMI VENUS
IPC: A61K47/12
Filed: 2019-10-14
Abstract: The present invention relates to stable formulations comprising antibodies or antigen-binding fragments thereof that bind to respiratory syncytial virus (RSV). Also provided are methods of preventing and/or treating RSV-related diseases with the formulations of the invention.
Patent CA-3116677-A1 (CA)
Title: Characterizing fracture orientations in orthorhombic adjacent layers using the phase of azimuthal fourier coefficients
Inventor: ROURE BENJAMIN
IPC: G01V1/30
Filed: 2021-04-30
Abstract: Methods and apparatuses characterize fracture orientations in orthorhombic adjacent layer. Seismic data with azimuthal coverage enables calculating Fourier coefficients of reflectivity at an interface between the orthorhombic adjacent layers. The phases of 2nd and 4th FCs may be used to infer the fracture orientations in the orthorhombic adjacent layers. Analysis of 2nd and 4th Fourier coefficients' phases for different incidence angles may indicate that the fracture orientations in the orthorhombic adjacent layers are aligned, orthogonal, at 45 , that one of the layers is isotropic, etc.
Patent CA-3119717-A1 (CA)
Title: Mecanisme conforme pour exploiter des gouvernes de vol d'un aeronef pilote a distance
Inventor: PANDA AAYUSH
IPC: B64C13/28
Filed: 2021-05-27
Abstract: Un mécanisme conforme pour lexploitation de gouvernes de vol dun aéronef à voilure fixe piloté à distance est caractérisé par lutilisation dune charnière conforme entre un réceptacle attaché à une tige-poussoir dactionneur et un composant vertical attaché à la gouverne de vol au moyen dune base. Une force linéaire appliquée sur le réceptacle par la tige-poussoir est transmise comme un couple à la gouverne de vol, qui entraîne une déflexion de la gouverne de vol pour manuvrer laéronef. Lutilisation dune charnière conforme permet un jeu mécanique très faible, ce qui permet une commande très précise de la gouverne de vol de laéronef.
Patent CA-3130828-A1 (CA)
Title: Method for producing targets for physical vapor deposition (pvd)
Inventor: ZIKIN ARKADI
IPC: C23C14/34
Filed: 2020-02-24
Abstract: Method for building up and/or finalizing a PVD target whereasthe method comprises a process step where target material is added using an additive method.
Patent CA-3133856-A1 (CA)
Inventor: CONDIE ALLISON G
IPC: C09D175/02
Filed: 2020-03-19
Abstract: Disclosed is a coating composition comprising a first component and a second component. The first component comprises a diluent and a carbodiimide present in an amount of no more than 50 percent by weight based on total weight of the coating composition. The second component comprises a curing agent that chemically reacts with the carbodiimide, the curing agent comprising an active hydrogen-containing compound. The coating composition may be an adhesive composition or a sealant composition. Also disclosed is a method for treating a substrate comprising contacting at least a portion of a surface of the substrate with a composition of the present invention. Also disclosed is a substrate comprising a surface at least partially coated with a layer formed from a composition of the present invention. Also disclosed is an article comprising a first substrate and a second substrate and a composition of the present invention positioned between the first and second substrates.
Patent CA-3137146-A1 (CA)
Title: Jewelry system
Inventor: NAM GINA WOO
IPC: A44C5/20
Filed: 2020-04-24
Abstract: The disclosed jewelry system is used for easily layering jewelry by connecting strands of similar types of jewelry, such as necklace strands, into a layered jewelry piece (e.g. multi-strand necklace), and which prevents tangling and provides a distinctive presentation of each layer. The present invention allows for variety in the combining and re-arranging of individual strands in any desired order, by the use of end couplers on the ends of each strand and one or more connector pairs disposed on one or more of strands. This allows for the creation of customized layered jewelry pieces that can be adjusted to suit a variety of styles. Such design allows for the use of singular strands to form into a layered jewelry piece that is distinctively presented in a symmetrical, cascading arrangement, which moves uniformly as one piece with the weight of gravity, virtually eliminating the risk of tangling.
Patent CA-3137597-A1 (CA)
Inventor: LE KIM H
IPC: G16B20/00
Filed: 2020-04-30
Abstract: L'invention concerne un procédé destiné à faciliter une sélection de lignées cellulaires pour passer à un stade suivant de criblage de lignées cellulaires consistant à recevoir de premières valeurs d'attribut pour les lignées cellulaires candidates mesurées à l'aide d'un système de génération et d'analyse de lignée cellulaire opto-électronique, et acquérir des secondes valeurs d'attribut qui comprennent une ou plusieurs valeurs d'attribut mesurées au niveau d'un étage de criblage de groupe de cellules des lignées cellulaires candidates. Le procédé comprend également une détermination d'un classement des lignées cellulaires candidates selon un attribut de qualité de produit associé à des cultures de criblage hypothétiques à petite échelle. La détermination du classement consiste à prédire, pour chacune des lignées cellulaires candidates, une valeur de l'attribut de qualité de produit par analyse de la première et de la seconde pluralité de valeurs d'attribut à l'aide d'un estimateur de régression basé sur un apprentissage machine, et à comparer les valeurs prédites. Le procédé consiste également à amener une indication du classement à être présentée à un utilisateur par l'intermédiaire d'une interface utilisateur.
Patent CA-3141501-A1 (CA)
Title: Transport system and transportable storage container for a vehicle bed
Inventor: MANNONE RICHARD K
IPC: B60P7/10
Filed: 2021-12-09
Abstract: The present disclosure is directed to a cargo moving system for moving storage units from the front of a truck bed to the rear and back again. The disclosed product is made of two components, a rail system, and a customizable storage unit. In a pickup truck embodiment, the rail system sits on top of vertical rails disposed on or in a pickup truck bed that can run from the cab to the tailgate. A storage unit sits on the rails or tracks and is moved by a motorized or manual transport system.
Patent CA-3141677-A1 (CA)
Title: Dispositif de pilotage d'un aeronef et procede associe
Inventor: LE BORLOCH JEROME
IPC: G05D1/10
Filed: 2021-12-08
Abstract: Dispositif de pilotage d'un aéronef et procédé associé. Le dispositif de pilotage comprend : un premier et un deuxième manches montés mobiles sur un support, un système de détection des positions des premier et deuxième manches, un mécanisme élastique configuré pour appliquer une force de rappel au deuxième manche, un premier et un deuxième systèmes d'actionnement configurés pour appliquer une première, respectivement deuxième, force d'ajustement de position au premier, respectivement deuxième, manche, un module de commande configuré pour commander la deuxième force d'ajustement de sorte que les positions des premier et deuxième manches soient identiques. Le module de commande est configuré pour commander la première force d'ajustement en fonction de la deuxième force d'ajustement et de la force de rappel.
Patent CA-3144425-A1 (CA)
Title: Pressurizable fluid container and valving structure thereof
Inventor: STOCKTON BOB
IPC: F17C1/00
Filed: 2020-05-12
Abstract: A container has a top and a bottom endcap, a bottle sandwiched therebetween, and one or more bands coupling the top and bottom endcaps and the bottle. The bottle receives therein a flexible bladder. At least one of the top and bottom endcaps has a pair of opposing parallel surfaces, one of which has a protrusion extending therefrom and the other one of which has a recess therein at a location corresponding to that of the protrusion. A valving structure demountably engages with a neck portion of the bottle and has (i) a coupling valve assembly having two channels in fluid communication with the bottle and the bladder for injecting gas thereinto and dispensing liquid therefrom, respectively, and (ii) a twist-lock casing receiving therein the coupling valve assembly and removably coupled to the bottle's neck portion. The twist-lock casing has a structure for safely depressurizing the bottle.
Patent CA-3144550-A1 (CA)
Inventor: GRASS MICHAEL
IPC: A61B90/00
Filed: 2019-12-10
Abstract: L'invention concerne un système de suivi permettant de suivre un dispositif marqueur destiné à être fixé à un dispositif médical, le dispositif marqueur comprenant une unité de détection comprenant un objet magnétique qui peut être excité par un champ d'excitation magnétique ou électromagnétique externe en une oscillation mécanique de l'objet magnétique, et le système de suivi comprend un générateur de champ permettant de générer un champ d'excitation magnétique ou électromagnétique prédéterminé afin d'induire des oscillations mécaniques de l'objet magnétique, un transducteur permettant de convertir le champ magnétique ou électromagnétique généré par les oscillations mécaniques induites de l'objet magnétique en un ou plusieurs signaux de réponse électriques, et une unité de détermination de position permettant de déterminer la position du dispositif marqueur sur la base du ou des signaux de réponse électriques.
Patent CA-3146459-A1 (CA)
Inventor: FURUTA TOMOYUKI
IPC: C07D239/95
Filed: 2020-08-28
Abstract: The present invention provides a 2-aminoquinazolinone derivative. The present invention is a compound represented by formula (1) [wherein X1 represents CR1 or N, X2 represents CR2 or N, X3 represents CR3 or N, Y represents an optionally substituted C6-10 aryl or optionally substituted 6 to 10-membered heteroaryl, Z represents an optionally substituted C6-10 aryl, RA represents a hydrogen atom, halogen, cyano, optionally substituted C1-6 alkyl sulfonyl, optionally substituted C1-6 alkyl, or optionally substituted C1-6 alkoxy, and R1, R2, and R3 independently represent a hydrogen atom, halogen, optionally substituted C1-6 alkyl, or optionally substituted C1-6 alkoxy] or a pharmaceutically acceptable salt thereof.
Patent CA-3146592-A1 (CA)
Inventor: SANCEY LUCIE
IPC: C09K11/06
Filed: 2020-08-04
Abstract: The present invention relates to the use of an aza-BODIPY fluorophore compound as a contrast agent in the optical window ranging from 1000 to 1700 nm. The invention also relates to the use, as a contrast agent, of a composition comprising said fluorophore compound and a pharmaceutically acceptable excipient and/or a solvent, in a kit comprising an injection system and said fluorophore or said composition, and also to a method for identifying a biological target (such as a healthy or tumour cell, a protein, DNA, RNA, for example).