baber/WOPTO huggingface dataset:
Patent CA-2670099-A1 (CA)
Title: Synthesis and biological activities of new tricyclic-bis-enones (tbes)
Inventor: HONDA TADASHI
IPC: C07C255/47
Filed: 2007-11-16
Abstract: This invention describes novel tricyclic-bis-enone derivatives (TBEs), such as TBE- 31, TBE-34, TBE-45 and water-soluble TBEs. The methods of preparing these compounds are also disclosed. The inventors demonstrate the ability of these new TBEs to inhibit proliferation of human myeloma cells, inhibit the induction of iNOS in cells stimulated with interferon-.gamma., induce heme oxygenase-1 (HO-1), induce CD11b expression - a leukemia differentiation marker, inhibit proliferation of leukemia cells, induce apoptosis in human lung cancer, and induce apoptosis in other cancerous cells. The TBEs of this invention are expected to be useful agents for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.
Patent CA-2673713-A1 (CA)
Inventor: FERGUSON MARK WILLIAM JAMES
IPC: A61K31/57
Filed: 2007-12-21
Abstract: Provided are antagonists of FXR activity for use as medicament for the prevention, reduction or inhibition of scarring. This use may preferably be to prevent, reduce or inhibit scarring formed on healing of wounds. The invention also provides corresponding methods of treatment. Preferred antagonists of FXR activity include guggulsterone (Z); guggulsterone (E); a scalarane; 80-574; and a 5.alpha.-bile alcohol. In advantageous embodiments, up to 32 µM of the antagonist of FXR activity may be provided per linear cm of wound, or cm2 of a wound or fibrotic disorder, over a 24 hour period in order to inhibit scarring.
Patent CA-2679804-A1 (CA)
Title: Implement frame with front folding wings and transport wheels
Inventor: POOLE GERALD W
IPC: A01B73/06
Filed: 2009-09-22
Abstract: An agricultural implement arrangement is disclosed that may provide wheel assemblies that are stored in front of wing assemblies and row units mounted thereon.  The arrangement may include actuators to extend the wheel assemblies in order to lift the row units off the ground to move to a transport position. When in a fully-folded position, the wing wheel assemblies may interleave. The arrangement may also shift the weight of the wing assemblies while in transport position to the hitch of the tractor and center the rearward weight over the central wheel assembly.
Patent CA-2681261-A1 (CA)
Inventor: FINSINGER DIRK
IPC: A61P35/00
Filed: 2008-02-22
Abstract: The invention relates to compounds of formula (I) wherein E, R3, R4, R5, X, Y, W, Q1, Q2, Z, s and m have the designations cited in claim 1. Said compounds can be used, inter alia, for the treatment of tumours.
Patent CA-2682093-A1 (CA)
Title: Antibodies, methods and kits for diagnosing and treating melanoma
Inventor: REITER YORAM
IPC: A61P35/00
Filed: 2008-03-27
Abstract: A method of diagnosing melanoma and antibodies capable of same are disclosed. The method comprises contacting a cell of the subject with an antibody comprising an antigen recognition domain capable of binding to an MHC-I molecule being complexed with a tyrosinase peptide, wherein the antibody does not bind the MHC-I in the absence of the complexed peptide, and wherein the antibody does not bind the peptide in an absence of the MHC, under conditions which allow immunocomplex formation, wherein a presence of the immunocomplex or level thereof is indicative of the melanoma. Methods for treating melanoma and antibodies capable of same are also disclosed. Pharmaceutical compositions comprising antibodies are also disclosed.
Patent CA-2682102-A1 (CA)
Title: Method and apparatus for processing utility waste with organic material content
Inventor: HAJDU ISTVAN
IPC: C02F3/28
Filed: 2008-03-27
Abstract: The method according to the invention contains steps wherein the waste is crushed to pieces of 8mm or smaller size, in a way that the empties are torn open and the organic residues therein are discharged; the non degradable waste is separated and the organic waste cleared from solid components is processed. In the crushing and sorting unit according to the invention the crushing screws (11) are screws of the same pitch direction and without central shaft, provided with short drive shafts (112) on their driven end, wherein the rotational axis of the discharging screw (151) and the plane determined by the rotational axes of the two crushing screws (11) define an acute angle. The heat treatment/mixing according to the invention contains a heat treatment tank, a mixing tank and a mixer unit, wherein the heat treatment tank (31) is arranged at the upper part of the mixing tank (32) coaxially surrounding the mixing tank (32); and the heat treatment tank (31) and the mixing tank (32) are interconnected by a quick discharge assembly.
Patent CA-2683168-A1 (CA)
Inventor: CONETE ERIC
IPC: F02K1/48
Filed: 2008-04-08
Abstract: The invention relates to a mixer (100) for the separated-flow nozzles of a turbojet, for mixing a hot inner flow from the turbojet combustion chamber with the cold outer flow from the turbojet fan. The mixer includes an inner shell (120) defining a flow channel for said hot inner flow, an outer shell (110) provided around the inner shell (120) and defining therewith a flow channel for said cold outer flow, and a lobe structure in which the lobes (1321, 1322) extend longitudinally from the trailing edges (HOa, 120a) of said shells. The lobe structure (130) is made of a ceramic-matrix composite material and is connected to the outer shell (110) by flexible connection tabs (140).
Patent CA-2684241-A1 (CA)
Inventor: RANDAZZO MICHAEL THOMAS
IPC: G16Z99/00
Filed: 2008-04-14
Abstract: A computer-implemented method for managing data for a clinical decision s upport system includes providing a computer management system including a se rver and a database, and downloading the decision support system onto the co mputer management system. The decision support system includes a plurality o f rules and receives data. The method also includes accessing the decision s upport system and issuing an alert associated with a predetermined data patt ern to at least one client system according to the rules, receiving a reques t for additional information from the at least one client system in response to the issued alert, determining additional data that has been requested, a nd retrieving the additional information associated with the issued alert.
Patent CA-2686168-A1 (CA)
Title: Method and apparatus for controlling screen configuration of broadcast contents received in digital broadcasting receiver
Inventor: AHN TAE-MIN
IPC: H04N5/445
Filed: 2009-11-17
Abstract: Disclosed a method and apparatus for providing received broadcast data in a digital broadcasting system. The apparatus for controlling a screen configuration in a digital broadcasting receiver includes: a data reception/conversion unit for receiving head-end-side data including configuration data of lattice-type moving picture contents sent through a broadcasting network, and converting the received data into content screen configuration data; and a content screen configuration unit for editing content screen configuration data converted by the data reception/conversion unit, disposing the content screen configuration data according to each category in a display means of a user terminal, and performing a control operation such that the first category and the last category among multiple categories displayed through the display means are cyclically connected and displayed.
Patent CA-2688807-A1 (CA)
Inventor: KLEINSASSER JONATHAN
IPC: A47B81/00
Filed: 2009-12-17
Abstract: A rack for storing elongate core sample boxes is formed from two separate frames each having three upright posts formed of tubular steel and a plurality of steel tubes extending across between the posts and welded to the posts. The frames can be transported in assembled form and then connected across the top and bottom of the uprights by metal bridging members with C-shaped inserts into the ends of the posts. The structure is held together and braced by diagonal braces which attach to tabs on the bridging members by a wedge drive into a slot in the tab.
Patent CA-2690637-A1 (CA)
Inventor: HATTENDORF HEIKE
IPC: C22C38/08
Filed: 2008-06-12
Abstract: The invention relates to an electric heating element, comprising an iron-nickel-chromium-silicon alloy, comprising in wt.%: 25 to 34% Ni, 12 to 26% Cr, 1.5 to 2.5% Si, > 0.1 to 0.7% Al, 0.1 to 0.7% Mn, 0.0005 to 0.05% Mg, 0.04 to 0.14%  C, 0.02 to 0.14% N, 0.0005 to 0.07% Ca, 0.002 to 0.02% P, max. 0.01% S, max. 0.005% B, at least one of the effective elements having affinity for oxygen of La, Ce, Y, Zr, Hf and Ti, with a content of La of 0.02 to 0.26%, and Ce, Y, Zr, Hf and Ti with a content 0.01 to 0.3%, wherein the sum PwE = 1.43 .cndot. X Ce + 1.49 - X La + 2.25 X Y +  2.19 .cndot. X Zr + 1.12 - X Hf + 4.18 .cndot. X Ti <= 0.38, PwE being the potential of the effective elements and X the content of the element in weight percent, and the remainder Fe and usual process-related impurities. Relative to corresponding known alloys, the present alloys have: significantly improved oxidation resistance and concomitant long service life; significantly improved dimensional stability at the application temperature;  and high specific electrical resistance in conjunction with the least possible change in the ratio of heat resistance/cold resistance to temperature (temperature coefficient ct).
Patent CA-2691566-A1 (CA)
Inventor: KOESTERS PETER HUBERTUS
IPC: C07C5/32
Filed: 2008-06-25
Abstract: Process for performing an endothermic reaction in a reactor containing catalyst tubes, the catalyst tubes containing a cata-lyst promoting the endothermic reaction, the process comprising the steps of a. contacting the catalyst contained in the catalyst tubes with a feed flow passing through the channels from an entrance end to an exit end, b. contacting an outer surface of the catalyst tubes with a flow of a heating medium having an initial heating temperature and flowing co-currently with the flow of feeds to heat the surface by convection, c. mixing at least part of the heating medium after hav-ing been contacted with the catalyst tubes with a flow of fresh heat-ing medium having a start temperature higher than the initial heating temperature to form the co-current heating medium having the initial heating temperature and reactor for carrying out the process.
Patent CA-2695182-A1 (CA)
Title: Jacking system
Inventor: VAN NOOD CORNELIS PIETER AARTDRIANUS
IPC: E02B17/08
Filed: 2008-07-10
Abstract: The invention relates to a jacking system for jacking a structure, in particular for jacking offshore platforms or vessels out of the water, said jacking system comprising a leg having a longitudinal axis and comprising first engagement parts along said leg, and a guiding frame displaceable along said leg, said guiding frame comprising at least a first, second, third and fourth actuator, said actuators each having a first and second actuator part which in operation can displace with respect to one another along said leg, said first actuator part of said actuators coupled to said guiding frame, said second actuator parts of s aid actuators each coupled to first engagement parts for engaging and disengaging said first engagement parts of said leg for providing abutment in the longitudinal direction of said leg, said second actuator parts of said actuators displaceable along said leg past one another, and said actuators being arranged in pairs opposite one another with respect to a longitudinal plane of said leg. This jacking system provides a faster jacking of for instance vessels for offshore construction.
Patent CA-2695423-A1 (CA)
Inventor: MILLER JASON
IPC: G01B5/06
Filed: 2008-08-04
Abstract: A gauge profile apparatus (100) includes a gauge profile system (104) and a lap count system (106) for determining an average three-dimensional profile over the length of a sheet coil (10). The gauge profile system (104) includes a lap profile measuring device (112) which will make a distance determination between top and bottom surfaces for the sheet coil (10).  The lap count system (106) includes a distance sensor (288) and camera (290) for determining the average thickness of the sheet coil (10). A second embodiment of the gauge profile system (400) is also provided, which utilizes a PDA (404), an ultrasonic tester (406) and a string encoder (432).
Patent CA-2696884-A1 (CA)
Inventor: WENIG ROBERT I
IPC: G06F15/173
Filed: 2008-06-02
Abstract: L'invention concerne un moniteur d'évènement d'interface d'utilisateur qui capture des évènements d'interface utilisateur exécutés par un client pendant une session de réseau. Un moniteur de session de réseau capture des données de réseau échangées entre le client et une application Internet pendant la session de réseau. Un dispositif de relecture identifie des évènements de commande dans la session de réseau qui nécessitent une exécution avant de relire des évènements d'interface utilisateur associés. Une relecture des évènements d'interface utilisateur est retardée par le dispositif de relecture jusqu'à ce que les évènements de commande associés aient été entièrement exécutés.
Patent CA-2698945-A1 (CA)
Inventor: CHUJO YOSHIKI
IPC: A61K49/00
Filed: 2008-09-03
Abstract: The present invention provides a contrast agent which ensures 1) high contrast performance, 2) low toxicity, and 3) a simple production process.   The present invention provides a contrast agent containing a silsesquioxane represented by General Formula (I), [Chem. 1]     (see formula I) wherein R1, the same or different, is a substituent bonded to Si through a carbon atom, the substituent having, at its terminal, a group represented by General Formula (II), [Chem 2.] (see formula II) wherein p represents an integer of from 1 to 5; q is the same or different, and represents an integer of from 1 to 5;  R2 is the same or different, and represents hydrogen atom, alkyl group, aralkyl group or acyl group, or a group represented by General Formula (III), [Chem.3]     (see formula III) wherein p, q and R2 are the same as above.
Patent CA-2699382-A1 (CA)
Title: Modulators of cystic fibrosis transmembrane conductance regulator
Inventor: BINCH HAYLEY
IPC: C07D471/04
Filed: 2008-09-15
Abstract: The present invention relates to modulators of ATP-B inding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Patent CA-2703574-A1 (CA)
Inventor: LEWIS RICHARD PAUL
IPC: A47K10/38
Filed: 2008-12-01
Abstract: Disclosed is a sanitary or no-touch dispenser which dispenses sheets of a web material, such as a paper towel. The disclosed dispenser provides the web material to a user by using both manual and electronic means to dispense the sheet. This is accomplished by having a motor engagably connected to an actuator roller. The motor is activated by a motor activation means, such as a switch. The motion of the actuator roller, which is started by the user grabbing and pulling a tail of the web material extending from the dispenser, causes the motor activation means to activate the motor which in turn drives the actuator roller to continue it its rotation motion to dispense the sheet from the dispenser.
Patent CA-2705105-A1 (CA)
Inventor: MELERO BERMEJO IGNACIO JAVIER
IPC: A61K38/21
Filed: 2008-11-07
Abstract: The invention relates to therapeutic compositions for the treatment of cancer and, more specifically, compositions containing an agonist ligand for receptor 4-1BB and a type-1 interferon, the simultaneous or sequential delivery of which results in a synergic antitumour effect in relation to the individual delivery of any of the components. The invention also relates to the therapeutic uses of the combinations of the invention for the treatment of cancer. The invention further relates to polynucleotides that code for compounds, vectors and cells containing same, as well as to the use thereof for the treatment of cancer.
Patent CA-2706775-A1 (CA)
Inventor: NIDDAM-HILDESHEIM VALERIE
IPC: C07C213/10
Filed: 2008-11-26
Abstract: Provided are crystalline forms of O-desmethylvenlafaxine fumarate, methods for their preparation, and pharmaceutical compositions thereof.
Patent CA-2708802-A1 (CA)
Inventor: STEIMEL JOHN C
IPC: F28D1/047
Filed: 2010-06-30
Abstract: A heat exchanger including a heat exchange fluid inlet, tubing coupled to the heat exchange fluid inlet, the tubing being configured to direct a flow of heat exchange fluid through the heat exchanger, the flow of fluid having a main fluid flow direction, and an air inlet configured to direct a flow of air in a generally collinear relationship with the main fluid flow direction.
Patent CA-2710094-A1 (CA)
Inventor: BENITEZ PABLO
IPC: F21Y101/00
Filed: 2008-12-18
Abstract: A condenser for directing light from a UHP arc lamp or other generally cylindrical source onto a target such as a microdisplay in line with a front end of the lamp comprises a primary mirror to direct light from the source towards the back end of the condenser, and a secondary mirror at the back end of the condenser to direct the light from the primary mirror onto the target.
Patent CA-2711415-A1 (CA)
Inventor: NISHIYAMA YOSHITAKA
IPC: C22C38/00
Filed: 2009-02-23
Abstract: A metal material which exhibits both excellent workability and excellent metal dusting resistance and which is suitable for use as the material in a cracking furnace, a reforming furnace, a heating furnace, or a heat exchanger in petroleum refining or petrochemical plants or the like. A carburization-resistant metal material characterized by containing by mass C: 0.08 to 0.4%, Si: 0.6 to 2.0%, Mn: 0.05 to 2.5%, P: 0.04% or less, S: 0.015% or less, Cr: 18 to 30%, Ni: 20 to less than 30%, Cu: 0.5 to 10.0%, Al: 0.01 to 1%, Ti: 0.01 to 1%, N: 0.15% or less, O(oxygen): 0.02% or less with the balance consisting of Fe and impurities and by satisfying relationship (1). The material may further contain one or more of Co, Mo, W, B, V, Zr, Nb, Hf, Mg, Ca, Y, La, Ce and Nd. C>= 0.062×Si + 0.033×Cu - 0.004×Cr +  0.043 (1) (wherein each symbol of element represents the content of the element in mass%)
Patent CA-2714401-A1 (CA)
Inventor: BRIGHT DAN
IPC: A61K35/618
Filed: 2008-12-12
Abstract: A method of modulating inflammation in an organism, which includes administering to an organism a composition including a therapeutic amount of an extract from the plant Biota orientatis.  Several key components of the extract of Biota orientalis have been identified that have also been shown to have an effect in dramatically reducing inflammatory responses.
Patent CA-2714484-A1 (CA)
Inventor: LIE TERJE LENNART
IPC: E21B47/00
Filed: 2008-02-07
Abstract: There is provided a monitoring system (300) for monitoring within a borehole (10). The system (300) comprises a probe assembly (100) operable to be moved within the borehole (10) for sensing one or more physical parameters therein, a data processing arrangement (110) located outside the borehole (10), and a data communication link (120) operable to convey sensor data indicative of the one or more physical parameters from the probe assembly (100) to the data processing arrangement (110) for subsequent processing and display and/or recording in data memory (140). The probe assembly (100) includes one or more sensors (320) for spatially monitoring within the borehole (10) and generating corresponding sensor signals (360). Moreover, the probe assembly (100) includes a digital signal processor (310) for executing preliminary processing of the sensor signals (360) to generate corresponding intermediately processed signals (370) for communication via the data communication link (120) to the data processing arrangement (110). Furthermore, the data processing arrangement (110) is operable to receive the intermediately processed signals (370) and to perform further processing on the intermediately processed signals (370) to generate output data for presentation (130) and/or for recording in a data memory arrangement (140). The system (300) is of benefit in that it enables real-time spatial monitoring of the borehole (10) to be achieved.
Patent CA-2714855-A1 (CA)
Inventor: YASUGI AKIRA
IPC: H02P9/00
Filed: 2009-06-05
Abstract: It is an object to prevent a damage on electric devices in a case where a generator is installed in a cold weather.  The invention provides a wind turbine generator 2 including: a power supply unit 23 connected to a utility grid 10 via a switch gear 3; a utility grid voltage measuring unit 26 provided between the power supply unit 23 and the utility grid 10, for measuring a voltage of the utility grid 10; and a temperature measuring unit 21 for obtaining an ambient temperature of the power supply unit 23. In a case where a measurement value of the temperature measuring unit 21 or an ambient temperature of the power supply unit 23 estimated based on the measurement value is smaller than a first temperature threshold determined based on a function guarantee temperature of the power supply unit 23 and the voltage measured by the utility grid voltage measuring unit 26 is smaller than a preset voltage threshold, the switch gear 3 operates to interrupt the connection between the power supply unit 23 and the utility grid 10.
Patent CA-2714869-A1 (CA)
Inventor: SMITH CHARLES RAY
IPC: F04D17/16
Filed: 2002-10-24
Abstract: An oven includes an oven cavity, at least one heat source for heating the cavity, and only one reversible fan assembly. The fan assembly includes a reversible motor, a shaft coupled to the motor and a fan coupled to the shaft.  The fan assembly may change cavity airflow pattern by reversing fan rotation. A  controller operationally coupled to the motor operates the oven in one of a first mode and a second mode. Upon determining to operate the oven in the first mode, the fan is rotated in a first direction for a first predetermined time period and is rotated in a different, second direction for a second predetermined time period. Upon determining to operate the oven in the second mode, the fan is rotated in the first direction for a third predetermined time period and is rotated in the second direction for a fourth predetermined time period.
Patent CA-2716754-A1 (CA)
Title: Compositions moussantes peu irritantes renfermant un surfactant a faible degre depolymerisation et un epaississant micellaire
Inventor: FEVOLA MICHAEL J
IPC: A61K8/72
Filed: 2010-10-06
Abstract: Une composition moussante peu irritante est présentée renfermant un surfactant à faible degré de dépolymérisation qui est un paraphényle diamine, un épaississant micellaire sélectionné parmi un groupe comprenant des épaississants corona comprenant au moins deux fractions hydrophobes linéaires en C18-C24 et des épaississants corona qui sont des esters dacide gras dalcools gras éthoxylatés et un support acceptable cosmétiquement où le surfactant à faible degré de polymérisation comporte au moins 7 et moins de 2000 motifs de répétition amphiphiles selon une base moyenne pondérée, où les motifs de répétition amphiphiles renfermant au moins 10 moles de pourcentage du surfactant polymérisé; lépaississant micellaire étant un polymère qui : (I) a un poids moléculaire moyen par poids de moins de 100 000; (ii) comprend au moins trois motifs de répétition hydrophiles ou motifs de répétition super hydrophiles et (iii) comprend au moins deux fractions hydrophobes indépendantes; et le paraphényle diamine est un surfactant polymérisé ayant n motifs de répétition amphiphiles et m motifs de répétition non amphiphiles, comme illustré ci-dessous : (Voir la formule ci-dessus).
Patent CA-2720013-A1 (CA)
Inventor: DE STROOPER BART
IPC: C07K16/40
Filed: 2009-04-03
Abstract: The present invention relates to single domain antibodies with a specificity for BACE1. More specifically, the invention provides single variable domain antibodies derived from camelids which bind to BACE1 and are capable of inhibiting the activity of BACE1. Said antibodies can be used for research and medical applications. Specific applications include the use of BACE1 specific antibodies for the treatment of Alzheimer's disease.