baber/WOPTO huggingface dataset:
Patent EP-0460058-A4 (EP)
Title: Use of bactericidal/permeability increasing protein or biologically active analogs thereof to treat lipopolysaccharide associated gram negative infections
IPC: A61P31/04
Filed: 1990-02-14
Abstract: The present invention provides a method of inhibiting lipopolysaccharide (LPS)-mediated stimulation of cells. This method comprises contacting the cells, in the presence of a cell-stimulating amount of lipopolysaccharide, with bactericidal/permeability increasing protein (BPI) in an amount effective to inhibit cell stimulation.
Patent EP-0462201-A4 (EP)
Title: Improved card embossing machine and method
IPC: B41F19/02
Filed: 1990-03-05
Abstract: An embossing machine and method is provided in which the mass of the carriage assembly carrying the card to and from various operations in the machine is significantly reduced by the utilization of a card carrying carriage mounted for movement in one direction from side to side on the machine via a stationary motor. The carriage is mounted on a guide bar which, together with the carriage, moves from the front to the back of the machine via a stationary motor. A new card supply hopper is arranged to stack cards vertically and feed them to the carriage one-by-one as the carriage approaches the hopper. An embossing assembly is operated by a single interposer arranged in a crank drive or two interposers arranged between actuating levers and the rams of associated male and female embossing wheels. A topper assembly minimizes foil usage by winding up only that foil which has been used during the topping of the previous card. The embossed and topped card is fed to a stacking assembly either through an arrangement of wires which causes the card to waterfall into a stacker channel or to slide into contact with a pivoting loader which pivots the card into a stacker channel.
Patent EP-0471747-A4 (EP)
Title: Cell culture system
IPC: C12N5/071
Filed: 1990-05-04
Abstract: A cell culture apparatus (10) is provided which permits perfusion of medium into a cell culture chamber (12) and continuous harvest of a product wherein gases entrapped in the medium supply (18) or in the cell culture chamber (12) are eliminated from the system (10).
Patent EP-0454860-A4 (EP)
Title: Potential sensor using electro-optical crystal and method of measuring potential
IPC: G02F1/03
Filed: 1990-11-13
Abstract: A monolithic sensor (10) is constituted by epitaxially growing a high-resistance compound semiconductor (12) on a low-resistance compound semiconductor (11), and further forming a reflecting dielectric film (13) thereon. The low-resistance compound semiconductor (11) has a large band gap so that the probe light is not absorbed but passes therethrough. The semiconductor (11) has a lattice constant and a coefficient of thermal expansion close to those of the high-resistance compound semiconductor, and a resistivity of smaller than 10<+1> ohm.cm so that it can also be used for an electrode. The high-resistance compound semiconductor (12) has a large band gap so that light of a short wavelength can be used, since a change in retardation increases with the decrease in the wavelength of the probe light. The semiconductor (12) has a large electro-optical constant and a resistivity of greater than 10<5> ohms.cm. Therefore, a sensor is constituted maintaining good workability and very high surface accuracy permitting less optical deterioration.
Patent EP-0455829-A4 (EP)
Title: Board holder in printed board boring machine
IPC: B23Q11/00
Filed: 1990-11-30
Abstract: This invention relates to a board holder in a printed board boring machine and the holder has the following construction: upper board holders (33, 41, 45, 52, 56) whose tip surfaces project from the contact surface with a printed board (1) towards a table (6) are disposed outside the contact surface in such a manner as to be movable in an axial direction thereof and biasing devices (31, 40, 50, 55) for biasing the upper holder (33, 41, 45, 52, 56) with a force greater than attraction generated in the board holder (18) towards the table (6) are disposed. According to this construction, floating of an upper plate (2) at the time of boring of the printed board (1) can be prevented and boring efficiency can be improved by minimizing a wasteful moving distance of a drill (16).
Patent EP-0496875-A4 (EP)
Title: Methods for producing rna viruses from cdna
IPC: C12R1/91
Filed: 1991-08-20
Abstract: The present invention relates to methods for producing RNA virus cDNA, methods for producing viable, RNA virus and viable, RNA virus produced by those methods. The invention also related to a novel RNA virus cDNA, recombinant DNA molecules containing that cDNA and hosts transformed with those recombinant cDNA molecules. This invention further related to novel methods for screening for variants of a strain 3 poliovirus. This invention also related to methods for increasing the attenuation of a strain poliovirus.
Patent EP-0548281-A4 (EP)
Title: Membrane module
IPC: B01D61/36
Filed: 1991-09-10
Abstract: A spiral-wound pervaporation module, designed to achieve optimum permeate flow throughput. The module is of conventional design and construction, in that it incorporates membrane envelopes, within and between which are channels through which the feed and permeate streams flow. The feed and permeate channels are created by spacers on the feed and permeate sides of the membrane layers. The module is unconventional in that the permeate spacer is tailored for optimum permeate flow throughput. The tailoring is based on the discovery that the total permeate flow throughput from a module passes through a maximum as the resistance to vapor transport of the permeate spacer material is progressively decreased. The resistance to vapor transport along the permeate channel is kept below a value at which it has a significant adverse effect on the membrane flux and the membrane separation properties, yet at the same time the total module throughput is within an optimum range. When modules in accordance with the invention are made, the increase in throughput per unit membrane area that is obtained more than compensates for the loss in membrane area brought about as a result of the use of a thicker permeate spacer. The modules are particularly advantageous for containing high-flux, high-separation membranes, and for low-pressure pervaporization processes.
Patent EP-0578774-A4 (EP)
Title: Monoclonal antibodies to stem cell factor receptors
Inventor: LIN NANCY
IPC: A61K35/14
Filed: 1992-04-03
Abstract: The present invention relates to monoclonal antibodies specific for a cell receptor specific for human stem cell factor (hSCF) as well as pharmaceutical compositions containing such monoclonal antibodies and uses of such monoclonal antibodies.
Patent EP-0619119-A4 (EP)
Title: Stabilized parathyroid hormone composition.
Inventor: ENDO KEN-DAIBA
IPC: A61K47/26
Filed: 1992-12-08
Abstract: A highly safe, stabilized lyophilized preparation of a parathyroid hormone (PTH) containing PTH as the active ingredient and effective amounts of a sugar and sodium chloride as the stabilizers for PTH.
Patent EP-0619304-A4 (EP)
Title: 22-oxacholecalciferol derivative and production thereof.
Inventor: KATO MASAHIRO CHUGAI SEIYAKU K
IPC: A61P35/00
Filed: 1992-12-18
Abstract: A 22-oxacholecalciferol derivative represented by general formula (I) and a process for producing the same efficiently by reducing the amount of by-products, wherein R1 represents hydrogen or hydroxy, and R2 and R3 may be the same or different from each other and represent each C1-C5 alkyl. This compound has potent activities of inducing differentiation and suppressing proliferation and is promising as antitumor agent, antirheumatic, psoriasis curative and remedy for hyperparathyroidism. <CHEM>
Patent EP-0705167-A4 (EP)
Title: Release film with reduced transferable silicone material
Inventor: CHANG KEUNSUK PAUL
IPC: C09J7/02
Filed: 1992-12-18
Abstract: A release film for label stock and the like having: (a) a cavitated layer of a thermoplastic polymer matrix material within which is located a strata of voids, positioned at least substantially within at least a substantial number of each of the voids is at least one spherical void-initiating solid particle which is phase-distinct and incompatible with the matrix material, the void space occupied by the particle being substantially less than the volume of the void, with one generally cross-sectional dimension of the particle at least approximating a corresponding cross-sectional dimension of the void; the population of the voids being such as to cause a degree of opacity of less than 70% light transmission; at least one surface of the layer free of any coating tending to mask the surface affects of cavitation; and (b) opposite to this surface, a coating of a release material of a type having a tendency to partially transfer to any contacting surface.
Patent EP-0637246-A4 (EP)
Title: Methods of treating cancer using modified c-reactive protein.
Inventor: POTEMPA LAWRENCE A
IPC: G01N33/574
Filed: 1993-04-22
Abstract: The invention provides a method of treating cancer in a mammal comprising administering to the mammal an effective amount of modified C-reactive protein ("mCRP"). The invention also provides a method of treating cancer in a mammal comprising administering to the mammal mCRP in combination with another agent such as a chemotherapeutic compound, immunoadjuvant, or cytokine. The mCRP may be administered to the mammal in a pharmaceutically-acceptable carrier or in liposomes. The invention further provides a method of identifying cancer cells in a mammal using mCRP as an imaging agent.
Patent EP-0601199-A4 (EP)
Inventor: TERADA TOMOYUKI
IPC: B25J9/10
Filed: 1993-06-11
Abstract: Méthode permettant de donner des instructions avec efficacité et sûreté individuellement à chaque robot lorsque ces robots sont installés avec une forte densité. Une instruction d'alimentation manuelle étant introduite dans un régisseur B, les coordonnées de position instantanée des points caractéristiques Pi et Qj définies pour les robots A1 et A2 sont successivement simulées, mises à jour et mémorisées dans une mémoire à accès aléatoire. La distance R entre le point caractéristique Pi (i = 1 à la valeur finale) et le point caractéristique Qj (j = 1 à la valeur finale) est obtenue consécutivement. Chaque fois qu'une plus courte distance R entre les points caractéristiques est calculée, la valeur de cette distance est mise en mémoire dans un registre Rmin. Ainsi, la plus courte distance entre les robots A1 et A2 est calculée (étapes S1 à S12). En fonction de la plus courte distance Rmin, la vitesse d'alimentation manuelle effective V est accrue ou réduite (étapes S13 et S14).
Patent EP-0645977-A4 (EP)
Title: Integrated child seat module.
Inventor: CZAPSKI RICHARD J
IPC: B60N2/30
Filed: 1993-05-04
Abstract: A child seat module integrated with a rear vehicle seat, and including fold-down lower and upper segments, interconnected by a flexible and detachable hinge, and a plastic back panel mounted against the back frame of the bench seat. A plastic seat pad support platform is mounted on the inner surface of the lower segment. A pad having seat and back segments is removably mounted on the platform and against the back panel. A safety belt system is operably included in the module. The interconnected lower and upper segments are adapted to being folded down to form, with the platform and pad, a child seat cushion and leg support. Alternatively, the leg support may be removed for a child whose size is such that use of the leg support would be uncomfortable.
Patent EP-0656823-A4 (EP)
Title: Nose block assembly.
Inventor: ROBSON ANGUS PETER
IPC: B25D17/08
Filed: 1993-08-26
Abstract: In a rock-breaking apparatus of the type employing a striker pin and hammer providing shock absorbing means housed within the nose block to protect the nose block and its carrier from primary and/or recoil shock loads during use.
Patent EP-0676085-A4 (EP)
Title: A mirror assembly having means for emitting or receiving a predetermined narrow spectral band of light.
Inventor: ROBERTS JOHN KENT
IPC: F21V9/00
Filed: 1993-10-18
Abstract: A mirror assembly including an enclosure having an aperture, and defining a cavity, a light source or lamp for emitting light in predetermined wavelengths or an instrument for emitting or receiving light having predetermined characteristics, borne by the enclosure and positioned in the cavity; and a dichroic mirror borne by the enclosure and disposed in substantially occluding relation relative to the aperture, the dichroic mirror reflecting ambient visible light and being substantially transparent to the light emitted by the light source and instrument, or received by the instrument as the case may be.
Patent EP-0645416-A4 (EP)
Title: Resin-impregnated fiber sheet.
Inventor: MIYAJI SHINICHIRO
IPC: H05K1/03
Filed: 1994-03-29
Abstract: A fiber sheet impregnated with a resin composition mainly comprising poly-p-phenylene sulfide and having the degree of orientation of 0.3 to 0.9. The sheet is markedly improved in thermal resistance, thermal dimensional stability, dielectric characteristics and mechanical properties when folded, thus being suited for use as insulation base material for circuit boards and multilayer interconnection boards wherein higher-density and thinner circuits are necessitated.
Patent EP-0724628-A4 (EP)
Title: Transgenic animal model for cognitive disorders
Inventor: CHEN HOWARD Y
IPC: C12P21/02
Filed: 1994-07-19
Abstract: Transgenic mice with a human interleukin 1β gene is provided. The transgenic mice may be used to evaluate compounds affecting Alzheimer's Disease and other cognitive disorders.
Patent EP-0752884-A4 (EP)
Title: Method of treating auto-immune diseases using type one interferons
Inventor: BROD STALEY ARMSTRONG
IPC: A61P25/00
Filed: 1995-04-11
Abstract: The present invention provides a method of treating auto-immune diseases in an animal comprising the step of orally administering a type one interferon to said animal. Also provided is a method of reducing inflammation associated with an auto-immune disease in an animal comprising the step of orally administering a type one interferon to said animal.
Patent EP-0957842-A4 (EP)
Inventor: MORRISSEY GERALD
IPC: A61J13/00
Filed: 1996-02-27
Abstract: Appareil (1) comprenant un support (2) présentant une surface externe (5) et une surface interne (3), de forme sensiblement adaptée au sein d'une femme, et muni d'une saillie (7) présentant une surface de contact avec le mamelon sensiblement plate, en avancée par rapport au support, située de façon à entrer en contact, de façon sensiblement alignée, avec le mamelon du sein de la femme. Cet appareil empêche la lactation du sein sur lequel il est placé. L'invention porte également sur un procédé de régulation de la lactation humaine à l'aide de l'appareil décrit, consistant à placer en position l'appareil sur le sein, et à appliquer dessus une pression suffisante pour empêcher la lactation.
Patent EP-0815240-A4 (EP)
Title: Novel human cyclin-dependent kinase-like proteins and methods of using the same
Inventor: GIORDANO ANTONIO
IPC: C12N15/09
Filed: 1996-03-14
Abstract: Substantially pure human cyclin-dependent kinase-like proteins PITALRE and PISSLRE and isolated protein complexes that comprise PITALRE or PISSLRE are disclosed. Isolated nucleic acid molecule that encode PITALRE or PISSLRE, or a fragment thereof; recombinant expression vectors that comprise nucleic acid sequence that encode PITALRE or PISSLRE; and host cells that comprise such recombinant expression vectors are disclosed. Oligonucleotide molecules that consist of a nucleotide sequence complimentary to a portion of the nucleotide sequence that encodes PITALRE or PISSLRE are disclosed. Antibodies which bind to epitopes on PITALRE or PISSLRE are disclosed. Nucleic acid molecules that comprise a nucleotide sequence that encodes phosphorylation deficient PITALRE, or a phosphorylation deficient PI SSLRE; recombinant vectors and pharmaceutical compositions that comprise such nucleotide sequences are also disclosed. Methods of identifying compounds which inhibit PITALRE activity are disclosed.
Patent EP-0820446-A4 (EP)
Inventor: GILLIG JAMES R
IPC: C07D273/02
Filed: 1996-03-27
Abstract: La présente invention concerne un procédé efficace de réaction d'un acide de bis-indolyle de la formule (II), dans laquelle R1 représente de l'hydrogène ou un alkyle C¿1?-C4 et R, X et Y sont d'éventuelles substitutions, ceci afin de produire un acide bis-indolyloxallique la formule (III). Les composés correspondant à la formule (III) peuvent être facilement transformés en bis-indolylmaléimides.
Patent EP-0805501-A4 (EP)
Title: Thermoelectric device and thermoelectric cooler/heater
Inventor: SAKURAGI SHIRO
IPC: H01L35/34
Filed: 1996-07-30
Abstract: A thermoelectric chip unit (1) includes a chip substrate (2) into which the same number of n-type thermoelectric semiconductor devices and p-type thermoelectric semiconductor devices (3) are fitted. Therefore, the crystal of each thermoelectric semiconductor device (3) is difficultly split at a cleavage. The chip substrate (2) can be made of a flexible insulating material such as plastics or rubbers so as to give flexibility to the chip unit (1). A thermoelectric unit (4) is produced by fitting electrodes (5) to the thermoelectric chip unit (1). Each electrode (5) can also be made of a flexible material such as a thin copper plate so as to give flexibility to the thermoelectric unit (4). A thermoelectric module (6) is formed by fitting a flexible sheet or cover (8) to the thermoelectric unit (4). This thermoelectric module (6) can be used for a cooling device of a CPU of a computer or a semiconductor laser, thermostats, and so forth.
Patent EP-0842361-A4 (EP)
Inventor: GIORDANI ATTILIO G
IPC: F04D27/00
Filed: 1996-07-31
Abstract: Circulateur à rotor mouillé de refroidissement par caloporteur et de chauffage à l'eau chaude dans lequel un clapet de retenue (30) est placé au niveau de l'ouïe d'entrée (16) de la roue (18) de la pompe, ce qui permet d'en effectuer facilement l'entretien en extrayant le moteur (10) du circulateur et la roue (18). Ce clapet de retenue (30) se présente, de préférence, sous la forme d'un sous-ensemble de clapet (32) inséré de façon amovible dans l'ouverture au niveau de l'ouïe (16).
Patent EP-0868591-A4 (EP)
Title: Rolling door drive and mounting assembly
Inventor: LEIVENZON JACK
IPC: E06B9/70
Filed: 1996-12-20
Abstract: A rolling door drive assembly including a final drive unit for connection to a door, whereby the door may be rotated by the final drive unit about an axis to open and close the door, a motor, a drive between the final drive unit and the motor operatively engaged with the motor, one or more drive axes about which one or more components of the drive rotate to transfer drive from the motor to the final drive unit, an actuator to bring the drive to a first configuration at which the motor is engaged to drive the final drive unit through the drive and to bring the drive to a second configuration at which the motor is disengaged from driving the final drive unit, and a resilient spring for urging the drive into one of the configurations. The actuator includes a cam rotatable about a cam axis separate from the one or more drive axes. The cam acts to set the desired configuration of the drive.
Patent EP-0883374-A4 (EP)
Inventor: ACKER DAVID E
IPC: A61B17/00
Filed: 1997-02-14
Abstract: Un système pour déterminer l'emplacement d'une sonde à l'intérieur du corps d'un patient comporte une sonde (20) dotée de transducteurs de champ (21) de sonde et d'un ou plusieurs transducteurs de champ de référence (30)(32)(34). Les transducteurs de champ de référence sont fixés à un cadre(22) rigide mais repositionnable, conçu pour permettre le positionnement des transducteurs très près du corps: Les champs non ionisants sont transmis et détectés entre la sonde et les transducteurs de champ de référence, la position relative de la sonde par rapport à ces derniers étant déterminée en fonction des champs détectés.
Patent EP-0944398-A4 (EP)
Title: Percutaneous delivery system
Inventor: TOMLINSON ROD
IPC: A61K47/34
Filed: 1997-11-24
Abstract: The invention relates to a substantially homogenous liquid composition capable of percutaneous delivery of one or more physiologically active agents, the composition including a rate modulating polymer, a volatile solvent and at least one physiologically active agent, said rate modulating polymer being selected to enable modulation of the rate of delivery of said physiologically active agent. Methods of percutaneous delivery of active agents and of prophylactic or therapeutic antimicrobial, antifungal or antiviral treatment using the compositions of the invention are also described.
Patent EP-1012641-A4 (EP)
Inventor: NOLAN DANIEL A
IPC: G01M11/00
Filed: 1997-09-25
Abstract: Détecteur réparti (10) qui comporte une pluralité d'étages (24, 28, 32, 36, 40) connectés en série, chaque étage comprenant une longueur de fibre (12) conservant la polarisation exposée à un phénomène tel que la déformation mécanique ou la température à détecter. Des coupleurs intermode sont placés entre les fibres de détection (26, 30, 34, 38) des divers étages. La fonction globale de transfert du dispositif à une pluralité de longueurs d'onde est déconvoluée pour déterminer la biréfringence de chaque région de détection et surveille des phénomènes pluriels indépendamment les uns des autres.
Patent EP-0901480-A4 (EP)
Inventor: NUMMY LAURENCE J
IPC: C07D301/24
Filed: 1997-04-25
Abstract: Dans un procédé de préparation de dérivés d'oxiraneméthane utiles comme intermédiaires dans la préparation d'inhibiteurs de l'aspartyle protéase, on active un aminodiol, on l'acyle et on met à réagir l'aminodiol acylé avec une base de façon à obtenir un composé époxy.
Patent EP-0914120-A4 (EP)
Inventor: JUNGHEIM LOUIS N
IPC: C07D409/12
Filed: 1997-06-05
Abstract: L'invention porte sur une série de composés de benzimidazole inhibant la croissance des picornavirus tels que le rhinovirus, l'entérovirus, le poliovirus, le virus Coxsackie des groupes A et B, l'échovirus, le virus de Mengo, et les flavivirus tels que l'hépatite C et le virus de la diarrhée bovine.
Patent EP-0929359-A4 (EP)
Inventor: HOWK RICHARD A
IPC: B01F3/04
Filed: 1997-10-03
Abstract: Dispositif et procédé de barbotage. Ledit dispositif comporte une cuve (10) à chicanes internes (20), un impulseur axial (12) de flux créant un flux descendant pour liquides, et une pluralité de tuyaux d'évacuation (30) des gaz expulsant les gaz contre des ailettes de répartition de flux, sur les surfaces inférieures de plaques sur lesquelles est monté un anneau de piégeage de l'air (32).
Patent EP-0989812-A4 (EP)
Title: Tab-style locking mass lipstick cup
Inventor: BOUIX HERVE FRANCOIS
IPC: A45D40/06
Filed: 1998-06-17
Abstract: The present invention is a holder cup for a stick-type product which comprises a hollow housing which is configured to receive a stick-type product. The hollow housing has a wall which contains at least one aperture. A tab capable of occupying a first open position or second locked position is pivotally mounted within an aperture. The tab has an outer cam surface which extends past the outside of the wall of the housing, and has a notch which fits the wall of the housing when the tab is in the second position. When the tab is caused to pivot toward the center of the holder cup the tab punctures the product and locks in place, thus preventing the release of the product from the holder cup.
Patent EP-1012339-A4 (EP)
Inventor: LEHMANN DONALD J
IPC: C12Q1/6883
Filed: 1998-09-01
Abstract: L'invention concerne un procédé permettant de déterminer la propension ou la prédisposition d'un sujet humain à développer tardivement la maladie d'Alzheimer. Ce procédé consiste à déterminer la présence chez ce sujet humain d'un gène 1) d'une variante k de la butyrylcholinesterase, et d'un gène 2) de l'apolipoprotéine E4, la présence du gène 1) ou des gènes 1) et 2) susmentionnés indiquant la propension ou la prédisposition à développer tardivement la maladie d'Alzheimer.