Patent EP-1813937-A1 (EP)
Inventor: MARQUANT MICHAEL
IPC: G01N33/487
Filed: 2006-01-25
Abstract: The electrochemical biosensor analysis system for analyzing body fluid, comprises a biosensor with a support layer for unique use, an electrode structure (16) arranged on the support layer with two electrodes (17,18), a suitable test field arranged on the support layer, which covers the electrode structure for the reception of the body fluid, a sample assignment area arranged on the top side turned away from the support layer of the test field, and an evaluator with an analysis measuring equipment positioned in a measuring position for measuring the measured variables and with a measurement module. The electrochemical biosensor analysis system for analyzing body fluid, comprises a biosensor with a support layer for unique use, an electrode structure (16) arranged on the support layer with two electrodes (17,18), a suitable test field arranged on the support layer, which covers the electrode structure for the reception of the body fluid, a sample assignment area arranged on the top side turned away from the support layer of the test field, an evaluator with an analysis measuring equipment positioned in a measuring position for measuring the measured variables and with a measurement module electrically connected to the biosensor, and an evaluation unit for determining the desired analysis data from measured values of the measurement variable. The test field contains a reagent system, in which the reaction with the body fluid to an alternation of an electric effect leads for measured variable of the desired analytical characteristics, which can be measured by an analysis measurement under use of electrodes of the electrode structure. The electrode structure on an effective electrode structure area (23) homogenously distributes the wettable sample fluid to alternating current (AC) resistant measurement at a fluid layer with a defined conductivity and layer thickness. The test field is formed to a drop sample fluid abundant on the sample assignment area. The sample fluid spreads itself over a part area of the sample assignment area and is wetted in a corresponding part area of the electrode structure surface. The analysis system shows temperature-measuring equipment for measuring the temperature of the test field. The evaluator exhibits an Ac resistance measuring instrument to measure the AC resistance between the electrodes, a heating mechanism for heating the test field of the biosensor positioned in the measuring position, and a thermostatization electronics for thermostatization of the test field by the temperature measuring equipment and the heating mechanism on a desired temperature. The measured Ac resistance is used in the determination of the analyze data as measure for the wettable part area of the effective electrode structure area by the sample fluid. The AC resistance readings use to eliminate measuring errors, which are caused by concentrations varying from measurement to the measurement of corpuscular components in the sample fluid or by a change of temperature of the test field. Alternating voltage of different frequencies is applied at the electrodes during the measurement of the AC resistance measuring values. The biosensor is formed as long stretched test strip with an introducing end arranged for introducing the evaluator into a support and with an operation end arranged opposite to the introducing end. The test field is arranged between the introducing end and the support end. The biosensor positioned in a support of the evaluator is supported by a biosensor bearing opposite to the adjacent component of the evaluator. The biosensor component is a biosensor strip consisting of majority of biosensors connected with one another. Independent claims are included for: (1) a biosensor for analysis system; and (2) a procedure for the analysis of body fluid.