baber/WOPTO huggingface dataset:
Patent DK-1664319-T3 (DK)
Inventor: BEURRET MICHEL FRANCOIS
IPC: A61K39/385
Filed: 2004-09-10
Granted: 2010-05-10
Abstract: A method for producing a polysaccharide and a conjugate vaccine including the polysaccharide produced according to the method. A characteristic step in the method is that the pH of the culture medium is kept at a constant value with base or acid until adjustment with respectively base or acid is not possible anymore. Using the method, capsular polysaccharide may be obtained in a high yield in a relatively short time. The method is straightforward, reproducible and cost-effective.
Patent DK-1642987-T3 (DK)
Inventor: MONCANY MAURICE
IPC: C07K16/00
Filed: 1990-06-05
Granted: 2008-12-01
Abstract: Oligonucleotide (I), comprising a specific sequence (A) of the gene gag or gene pol, and susceptible to hybridize at 60[deg]C+-1[deg]C with the genomes of viruses HIV-1 Bru, HIV-1 Mal, HIV-1 Eli, HIV-2 Rod or SIV Mac; or a sequence complementary to a sequence (A), is new. Independent claims are also included for: (1) couple of oligonucleotide primers (II), for carrying out a gene amplification of the gene gag or gene pol of the virus of the type HIV-1 Bru, HIV-1 Mal, HIV-1 Eli, HIV-2 Rod or SIV Ma, where the primers consists each one of: a specific sequence of the gene gag or gene pol, and susceptible to hybridize at 60[deg]C+-1[deg]C with the genomes of viruses HIV-1 Bru, HIV-1 Mal, HIV-1 Eli, HIV-2 Rod or SIV Mac; or a sequence complementary to the sequence (A); (2) a process of gene amplification of nucleic sequences of the gene gag or the gene pol of virus of type (HIV-1 and/or HIV-2, and/or SIV, from a biological sample, comprising: (a) a stage of extraction of the nucleic acid to be detected belonging to the genome of the virus of the HIV-1 type, HIV-2 or SIV, optionally present in the biological sample, and optionally a stage of treatment using a reverse transcriptase of the nucleic acid if the latter is in the form of RNA; (b) a cycle comprising: denaturation of the double stranded nucleic acid to be detected, which leads to the formation of a single strand nucleic acid, hybridization of each strand of nucleic acid, obtained at the stage of denaturation, with at least a primer or a couple of primers of (II), by setting in contact the strands with at least a couple of the primers, formation from primers, of complementary DNA strands on which they are hybridized in the presence of a DNA polymerase and four different nucleosides triphosphate (NTP), which leads to the formation of a greater number of double strand nucleic acid to be detected at the stage of preceding denaturation, and repetition of the cycle for a determined number of times to obtain the nucleic sequence to be detected optionally present in the biological sample in a proportion sufficient to allow its detection; and (c) a stage of detection of the optional presence of the nucleic acid belonging to the genome of the virus in the biological sample; and (3) a kit for carrying out the process of gene amplification of nucleic sequences of the gene gag or the gene pol of virus of type (HIV-1 and/or HIV-2, and/or SIV, from a biological sample, comprising: at least a primer or a couple of oligonucleotidic primers of (II); reagents appropriate to be used in cycle of amplification, in particular DNA polymerase, four different nucleotide triphosphate, and buffer 10X; and one (or several) probe, can be marked, capable of hybridizing with the amplified sequence of nucleic acid to be detected.
Patent DK-1729880-T3 (DK)
Inventor: SONGE PAL
IPC: B01J20/32
Filed: 2005-03-17
Granted: 2008-09-22
Abstract: A process for covalently binding a tagged protein to a polymer particle comprising: contacting a tagged protein with a chelating agent-polymer particle conjugate wherein said tag comprises at least two histidine residues and at least two lysine residues and said chelating agent is tridentate, tetradentate or pentadentate and comprises at least two carboxyl groups and is coordinated by Co<SUP>2+</SUP> ions, to form particle-chelating agent Co<SUP>2+</SUP> complex: contacting said complex with a carbodiimide; and optionally removing the Co<SUP>2+</SUP> ions.
Patent DK-1712341-T3 (DK)
Inventor: SPULLER SWEN
IPC: B29C45/27
Filed: 2006-03-30
Granted: 2008-11-10
Abstract: Injection molding nozzle with at least two outlet openings (1) and at least one force-controlled closure element (2), by means of which a connecting opening (3) of an injection mold (4) can be closed. The new feature is that a short lifting device (5) is present and this can adjust (2) around a short lift against the closure direction (6) of (2).
Patent DK-1813541-T3 (DK)
Inventor: DUMMETT LAWRENCE W
IPC: B29C51/16
Filed: 2003-07-23
Granted: 2010-01-11
Abstract: A dunnage platform is in the general shape of a rectangular slab with legs extending form one side. The dunnage platform is made from an expanded polystyrene core. A chemical combination process is used to chemically combine portion of the core proximal to its surface with high impact polystyrene. In a first of two parts of the combination process, the core is placed in a forming mold with one of its two sides and two thirds of its thickness extending therefrom. A heated sheet of high impact polystyrene is brought into contact with the portion of the core extending from the mold. In a similar manner, the other of the two sides of the core is made to extend from the forming mold for contact with a heated sheet of high impact polystyrene.
Patent DK-1905858-T3 (DK)
Inventor: KAJINIC ALOJZ
IPC: C22C33/02
Filed: 2007-09-27
Granted: 2012-03-26
Abstract: A powder metallurgy cold-work tool steel article of hot isostatic compacted nitrogen atomized, prealloyed powder. The alloy of the article includes the addition of niobium, which combined with the use of gas atomization, results in a fine carbide size distribution. This in turn results in improved bend fracture strength and impact toughness. In addition, as a result of isostatic compaction of nitrogen gas atomized prealloyed powder a fine distribution of carbides results to obtain a microstructure that achieves both improved toughness and wear resistance.
Patent DK-2029120-T3 (DK)
Inventor: RADEMACHER THOMAS WILLIAM
IPC: A61K33/244
Filed: 2007-04-13
Granted: 2011-10-31
Abstract: Nanoparticles for providing immune responses for the treatment or prophylaxis of infection by infectious agents such as viruses, parasites, bacteria, prions and fungi are described which comprises a core including metal and/or semiconductor atoms, wherein the core is covalently linked to a plurality of ligands, the ligands including a carbohydrate residue capable of stimulating an innate immune response, a T cell helper peptide and a danger signal. This platform may then be adapted by including one or more further ligands capable of producing a specific response to a target infectious agent.
Patent DK-2040566-T3 (DK)
Inventor: LOPEZ JAVIER MARTIN TERESO
IPC: A23K1/175
Filed: 2007-06-14
Granted: 2011-05-16
Abstract: The invention relates to a ruminant feed supplement for the treatment of milk fever. According to the invention rice bran that has been subjected to a ruminal bypass treatment is used in the feed of dairy cows. The ruminal bypass treatment may for instance be selected from the chemical cross-linking, physical cross-linking, coating, or combinations thereof. The invention further relates to the use of rice bran for the manufacture of a composition for the prophylactic treatment of parturient paresis in ruminants, wherein the rice bran has been subjected to a ruminal bypass treatment.
Patent DK-2040734-T3 (DK)
Inventor: HANSSON HANS-ARNE
IPC: A61K38/17
Filed: 2007-04-27
Granted: 2012-01-23
Abstract: The present invention relates to the use of an antisecretory factor (AF) protein, a homologue and/or a fragment thereof having antisecretory activity, and/or a pharmaceutically active salt thereof, for use in the treatment and/or prevention of a compartment syndrome associated with the presence of a benign and/or a malign tumour in a body. In one embodiment, said compartment syndrome is caused by a medical treatment of said tumour, such as treatment with X-ray, high energetic radiation, local cooling, local heating, light therapy and/or anti-tumour drugs.
Patent DK-2202762-T3 (DK)
Inventor: SOIKA RAINER
IPC: H01B12/02
Filed: 2008-12-15
Granted: 2011-05-23
Abstract: The arrangement has a superconducting screen (3) concentrically surrounding a superconducting conductor (1) with interposition of a dielectric (2). A superconducting cable (SK) is surrounded by a cryostat (KR), and encloses a free space (FR) for a coolant to be passed through. Vacuum insulation (6) is arranged between metallic tubes (4, 5). The screen is made of a superconducting material i.e. Yttrium barium copper oxide, whose electrical resistance value in normally conductive state is greater than electrical resistance value of the material used for the conductor in the conductive state. The superconducting conductor is made of Bismuth strontium calcium copper oxide, rare-earth barium-copper-oxide and copper.
Patent DK-2146569-T3 (DK)
Inventor: LEDU CHRISTOPHE
IPC: A01K67/033
Filed: 2008-03-19
Granted: 2011-09-19
Abstract: The invention relates to a method for producing viable tetraploid bivalve mollusks, by fertilisation of diploid female ovocytes with diploid male sperm, followed by the induction of the retention of the first polar body of the fertilised eggs, isolation from the obtained larvae of a larval sub-population enriched in tetraploids and selective raising of said sub-population.
Patent DK-3000813-T3 (DK)
Inventor: BIGGADIKE KEITH
IPC: C07D473/18
Filed: 2009-08-07
Granted: 2018-01-29
Abstract: Compounds of formula (I): wherein R1 is C1-6alkylamino, C1-6alkoxy, or C3-7cycloalkyloxy; m is an integer having a value of 3 to 6; n is an integer having a value of 0 to 4; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.
Patent DK-0395219-T3 (DK)
Inventor: BATESON JOHN HARGREAVES
IPC: A61P31/04
Filed: 1990-03-26
Granted: 1999-02-15
Abstract: beta -Lactam compounds of the formula (Ia) including pharmaceutically acceptable salts and in vivo hydrolysable esters, processes for their preparation and their use as antibiotics: <CHEM>  wherein  R<1> is hydrogen, methoxy or formamido; R<2> is an acyl group, in particular that of an antibacterially active cephalosporin;  CO2R<6> is a carboxy group or a carboxylate anion; R<3> is a  gamma -lactone ring optionally containing an endocyclic double bond, which ring is optionally substituted at any carbon atom by alkyl, dialkylamino, alkoxy, hydroxy, halogen or aryl, which in the case of more than one substituent may be the same or different, or is optionally di-substituted at two adjacent carbon atoms, which are available for substitution, to form an aromatic fused bicyclic system; and X is S, SO, SO2, O or CH2.
Patent DK-0470966-T3 (DK)
Inventor: COLE FRANCIS X
IPC: G01N33/543
Filed: 1990-03-07
Granted: 1996-09-30
Abstract: A simultaneous dual analyte assay for determining the fertile period of the human menstrual cycle. The assay utilizes a capture reaction component consisting of P-3-G immobilized on a microporous membrane, a blocking reaction component consisting of anti E1-3-G antibody, a labelled reaction component consisting of gold particle labelled anti E1-3-G antibody, and an ambifunctional reaction component consisting of a hybrid immunoreactive substance having an anti P-3-G antibody binding site and a plurality of E1-3-G determinant binding sites. An aqueous sample containing P-3-G and E1-3-G is contacted with the components and the assay is calibrated to provide a positive assay result only when the concentration of P-3-G in the sample is less than a predetermined concentration and the concentration of E1-3-G in the sample is more than a preselected concentration whereby a visually inspectable quantity of an immunocomposite is produced that consists of both the P-3-G immobilized on the microporous membrane and the gold labelled anti E1-3-G antibody.
Patent DK-0485413-T3 (DK)
Inventor: WIDLUND URBAN
IPC: A61F13/15
Filed: 1990-07-03
Granted: 1993-06-28
Abstract: A disposable, absorbent article such as a diaper or an incontinence guard includes an absorbent pad disposed between inner and outer casing layers. At least one of the inner and outer casing layers is made of an elastic material having areas from which material has been removed while leaving coherent material parts in order to impart different elastic properties to different parts of the material. The material removed can be in the form of through holes or blind holes.
Patent DK-0446730-T3 (DK)
Inventor: HERMENTIN PETER DR
IPC: G01N33/84
Filed: 1991-03-02
Granted: 1996-01-22
Abstract: The invention relates to monoclonal antibodies (MAbs) which bind with high specificity and avidity to water-soluble complexones such as ethylenediaminetetraacetate (EDTA) or diethylenetriaminepentaacetate (DTPA) and after complexation of EDTA or DTPA with metal ions retain their high avidity and specificity for these complexones. These MAbs can therefore be used, for example coupled to filters or other supports, for removing toxic heavy metals which are complexed with EDTA or DTPA. Furthermore, these MAbs are suitable as components of immunoassays (RIA, ELISA etc.) for the quantitative detection of EDTA and DTPA in aqueous solutions.
Patent DK-0471165-T3 (DK)
Inventor: AHONEN ANTTI ILMARI
IPC: H01R43/00
Filed: 1991-06-17
Granted: 1995-11-06
Abstract: A reliable superconducting contact for superconducting thin film components, based on soft superconducting materials, and a method for making the contacts. The joint, according to this invention, consists of a thin bonding slab having its end longitudinally cut so that double or multiple parallel joints can be made. In the method, a wire blank (1) is squeezed to a thin plate and then this plate (2) is cut to slabs (3) used in the bonding. The ribbon-like character and the thinness of the bonding slab permit a precise control of the bonding temperature and reduce the strain and bending forces caused by thermal contraction, preventing the contact from peeling off while cooling the superconducting component to the operational temperature.   <IMAGE>
Patent DK-0481522-T3 (DK)
Inventor: FLYNN GARY A
IPC: A61K31/55
Filed: 1991-10-18
Granted: 1998-03-09
Abstract: The present invention relates to certain novel mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and of ACE.
Patent DK-0448375-T3 (DK)
Inventor: EYRE CHRISTOPHER JOHN
IPC: B05C17/01
Filed: 1991-03-20
Granted: 1995-07-24
Abstract: A dispensing gun for viscous materials comprises a stock (12) supporting a push rod (28) which is advanceable along a keep (13) in which is mounted a cartridge of the material. The rod is advanced by means of a catch plate (41) and trigger (43) arrangement which bites on the rod and is retreated by a return spring (42). A release plate (51) prevents the rod retreating with the catch plate. The release plate is frictionally engaged with the rod so that it acts as a lost motion brake once force is removed from the trigger. In this way the rod is allowed a limited retreat to take the dispensing force off the cartridge to prevent leakage when the trigger is not depressed. <IMAGE>
Patent DK-0533703-T3 (DK)
Inventor: WILKS JOHN WILLIAM
IPC: C07J7/00
Filed: 1991-05-23
Granted: 2000-08-14
Abstract: Novel angiostatic  DELTA <4,9(11)>-steroids (I), C21-oxygenated steroids (II) and other known steroidal compounds have been found to be useful in treating angiogenesis in mammals who have a need for the same. These steroids are useful in treating diseases of neovascularization such as cancer, diabetes and arthritis.
Patent DK-0542314-T3 (DK)
Inventor: DEBENEDETTI PABLO G
IPC: C07K14/62
Filed: 1992-11-13
Granted: 1999-04-12
Abstract: A method of forming microparticles of a material which comprises bringing a supercritical antisolvent gas into contact with a solution of said material in a solvent at a controlled rate operable to expand the solution and precipitate the material.
Patent DK-0525163-T3 (DK)
Inventor: MARGALIT RIMONA
IPC: A61K38/22
Filed: 1991-10-30
Granted: 1995-09-25
Abstract: Crosslinking reagents glutaraldehyde and ethylene glycol diglycidyl ether have been used to bind epidermal growth factor ("EGF") to liposomal surfaces without utilizing the disulfide bridge linkage of EGF and, therefore, not adversely affecting the functionality of EGF. The crosslinking occurs through the amine residues offered by EGF and liposomes having phosphatidylethanolamine. The resulting EGF-modified liposomes offer potential as a microscopic drug delivery system.
Patent DK-0529064-T3 (DK)
Inventor: MYERS WARREN D
IPC: B29B15/10
Filed: 1992-03-06
Granted: 1995-10-09
Abstract: Honeycomb fabricated of non-crosslinked polymer is prepared by impregnating a fiber web with a linear prepolymer which is soluble in an organic solvent, and which is readily converted by thermal curing in the absence of a crosslinking agent to an insoluble form with a glass transition temperature exceeding 200 DEG  C., preferably exceeding 250 DEG  C. The preferred prepolymer is the product of diaminodiphenylsulfone and trimellitic anhydride, and forms a poly(amide-imide) upon cure. A process for forming the impregnated honeycomb is also disclosed, which involves impregnating ribbons or sheets, forming them into stacks bonded together at node lines, expanding the stacks into honeycomb structures, and heat soaking the expanded structures to cure the resin and stabilize the structure.
Patent DK-0592453-T3 (DK)
Inventor: TESCHENDORF HANS-JUERGEN
IPC: A61K31/506
Filed: 1992-05-11
Granted: 1999-08-23
Abstract: PCT No. PCT/EP92/01028 Sec. 371 Date Dec. 13, 1993 Sec. 102(e) Date Dec. 13, 1993 PCT Filed May 11, 1992 PCT Pub. No. WO92/22541 PCT Pub. Date Dec. 23, 1992.Aminoalkyl-substituted 2-amino-1,3,4-thiadiazoles of the formula    <IMAGE>  I  where n and A have the meanings stated in the description, and the preparation thereof are described. The compounds are suitable for controlling diseases.
Patent DK-0648744-T3 (DK)
Inventor: MOHACSI ERNO
IPC: A61P9/08
Filed: 1994-08-18
Granted: 1998-09-21
Abstract: Compounds of the formula <CHEM>     wherein   R   is hydrogen, hydroxy, or aryl lower alkyloxy; X   is hydrogen; Y   is hydroxy or hydrogen;     or both X and Y taken together are oxygen;   Z   is aryl lower alkyl; and m   is an integer from 1 to 4 or a diastereomer or an enantiomer thereof, except, the R,R diastereomer of formula I, wherein X is hydrogen, Y is hydroxy, R is benzyloxy, Z is benzyl, and m is 1, or pharmaceutically acceptable salts thereof, reduce adverse effects of toxic injury to central neurons and thus are useful in the treatment of ischemia, stroke, hypoxia and are NMDA receptor antagonists.
Patent DK-0616957-T3 (DK)
Inventor: MUNDHENKE ERICH
IPC: B65F1/00
Filed: 1994-03-24
Granted: 1999-07-26
Abstract: The invention relates to a holding device for a plurality of refuse receptacles below a work surface, preferably in a cupboard arranged below the work surface, having a standing base designed in the form of a segment of a circle which can be pivoted outwards about a vertical axis below the work surface or out of the cupboard, and preferably having a common covering for a refuse receptacle. According to the invention, screw-on bearing means (19, 25, 26, 27) are arranged on a side wall of the cupboard (1), adjacent to the cupboard door (4), or on a vertical post below the work surface (2), in which the standing base (5) and a cover (10) are mounted one above the other to be pivotable independently of each other so that they form a structural unit with the bearing means and can be released from their mounting by lifting. <IMAGE>
Patent DK-0617536-T3 (DK)
Inventor: MULLER JACQUES
IPC: H04M1/02
Filed: 1994-03-23
Granted: 2001-08-27
Abstract: The terminal includes a body (1) holding an earpiece (2) at one end and a tray (3) at the other end incorporating a microphone or constituting a means for reflecting the sound towards a microphone. The tray can be folded between a position for receiving the sound of the voice and a folded position intended to reduce the size of the appliance when the terminal is out of use or on standby. The power supply unit (14) is inserted into a cavity (16) of a plinth (8) of the tray (3) in such a way as to form an integral part of the tray in the fitted state. Used to reduce the size in terms of thickness and to enhance ease of handling. <IMAGE>
Patent DK-0703980-T3 (DK)
Inventor: SCHWEIGHOFFER FABIEN
IPC: C12N15/13
Filed: 1994-06-15
Granted: 2003-05-19
Abstract: PCT No. PCT/FR94/00714 Sec. 371 Date Dec. 28, 1995 Sec. 102(e) Date Dec. 28, 1995 PCT Filed Jun. 15, 1994 PCT Pub. No. WO94/29446 PCT Pub. Date Dec. 22, 1994The present invention relates to nucleic acid sequences encoding intracellular binding proteins. More particularly, the nucleic acid comprises a gene coding for an intracellular single chain antibody specific for a ras oncogene under the control of a promoter, the antibody is functional in mammalian cells, and inhibits the transformation of cells that express a ras oncogene.
Patent DK-0672378-T3 (DK)
Inventor: HANS RAAB
IPC: A47L13/42
Filed: 1995-02-10
Granted: 2004-10-18
Abstract: The handle comprising a metal tube is for a cleaning device, esp. for a window cleaning device. It has a textile tension arrangement for a tension frame to be connected to the handle by a cardan joint or for a sponge and/or an elastic wiping strip. The handle has a short section (1) which is put together with an extension piece (2). The short section and also the extended handle are provided at the end with a grip (8) consisting of a plastics casing. The grip extends over the metal tube of the short handle and covers over the seam between the end of the metal tube of the short handle and the metal tube of the extension piece. An intermediate piece (3) fits in the two metal tubes and consists of a metal tube which prevents bending.
Patent DK-0684419-T3 (DK)
Inventor: AMORETTI LUIGI
IPC: A47L11/34
Filed: 1995-05-22
Granted: 1999-09-13
Abstract: The extension coupling for fluid distribution equipment has a first external tubular body (18), a second internal tubular body (19) for the passage of said fluids, and a coupling (20,23-25) for its connection, in series, to other similar elements and/or handle connected to the distribution equipment and/or accessories. The first body (18) and the second body (19) are monolithic, and are obtained from one single molding process of plastic material.
Patent DK-0695721-T3 (DK)
Inventor: BASSE HARTWIG
IPC: C02F3/10
Filed: 1995-07-20
Granted: 2000-04-03
Abstract: A filling material is used as part of a biological filter, and consists of a tube-like structure with a latticed mantle surface. The novelty is that the mantle surface (22, 33, 74) of the basic lattice material (21, 32, 40, 45, 50, 53, 58, 62) is enlarged at different positions.
Patent DK-0749392-T3 (DK)
Inventor: DRISSLER HUBERT
IPC: B65D77/30
Filed: 1995-03-01
Granted: 1999-03-29
Abstract: A packaging bag for pourable products is made of a stable packing material, in particular of a paper-containing blank. In the filled state, the upper bag end (1) is folded at least once about a folding edge (4) and is secured at the bag region located below the folding edge (4), so forming a multi-layered edge region (5). By virtue of this arrangement, the packaging bag can be opened in a simple and easily manageable fashion without additional aids and without damaging any areas of the bag which are in contact with the product in the opening position. For this purpose, the upper bag end (1) is provided in the multi-layered edge region (5) with a tear-off device (6) for the free end region (8) of the multi-layered edge region (5).