baber/WOPTO huggingface dataset:
Patent CS-200550-B2 (CS)
Title: Method of producing dextrorotatory isomers of asymetric spiro-hydantoin compounds
Inventor: SARGES REINHARD
IPC: C07D495/10
Filed: 1978-05-11
Abstract: Several novel dextrotatory spiro-hydantoin compounds have been obtained by resolving the corresponding dl-compounds which are initially synthesized by first condensing the appropriate carbonyl ring compound, such as the corresponding 4-chromanone or thiochroman-4-one, as the case may be, with potassium cyanide and ammonium carbonate. The resulting optically-active hydantoin derivatives, such as d-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione and d-6'-fluoro-spiro-[imidazolidine-4,4'-thiochroman]-2,5-dione, are particularly useful in preventing or alleviating chronic diabetic complications.
Patent CS-252482-B2 (CS)
Inventor: BOROSS LASZLO
IPC: C12N11/08
Filed: 1984-03-29
Abstract: Způsob imobilizace enzymu karboxypeptidázy
B získaného zvláště ze slinivky
břišní savců. Enzym karboxypeptidázy B se
nanáší z roztoku v pufru o hodnotě pH
4,5 až 8,5 na aktivovaný nosič z kyseliny
akrylové a/nebo z kyseliny metakrylové
popřípadě z akrylamidu nebo metakrylamidu
obsahující alespoň 0,1 m ekv/g funkčních
karboxylových skupin. Takto imobilizovaný
enzym se promyje, skladuje se ve formě
vodné suspenze při teplotě 0 až 4 °C a
popřípadě suší.
Patent CS-201522-B2 (CS)
Title: Process for preparing benzimidazolcarbamates
Inventor: VAN GELDER JOSEPHUS L
IPC: A23K1/16
Filed: 1970-06-19
Abstract: 1307306 Benzimidazole derivatives JANSSEN PHARMACEUTICA NV 29 May 1970 [20 June 1969] 26044/70 Heading C2C Novel benzimidazole derivatives of the formula wherein R is C 1-6  alkyl, C 3-6  cycloalkyl , phenyl, halophenyl, C 1-6  alkylphenyl,. C 1-6  alkoxyphenyl or 2-thienyl, and R 1  is CH 3  or CH 3 CH 2 , and RCO is located at the 5(6)-position, are prepared by reacting compounds of the formula with aminoketones of the Formula V: in the presence of protonic acids. Aminoketones of Formula V above are obtained by hydrogenating the corresponding 4-amino-3-nitropheoyl ketones obtained by ammonolysis of the corresponding 4-halo-3-nitrophenyl ketones resulting from the Friedel- Crafts reaction between the appropriate 3-halo - 4-nitrobenzoyl chloride and compounds of the formula RH, or by nitrating the-corresponding 4-halophenyl ketones resulting from the Friedel- Crafts reaction between the appropriate halobenzene and carbonyl chlorides of the formula RCOCl. Antihelmintic compositions, suitable for the usual routes of administration, contain the above novel benzimidazole derivatives in admixture with suitable carriers.
Patent AU-563149-B2 (AU)
Title: Amide derivatives
Inventor: PRESTON JOHN
IPC: C07K5/06
Filed: 1983-01-13
Granted: 1987-07-02
Abstract: Amide derivatives of the formula:  <IMAGE>  wherein either R1 is aryl or heterocyclic and A1 is a direct link, or R1 is aryl or heterocyclic, or hydrogen, or halogeno, hydroxy, amino, guanidino, mercapto, carboxy, carbamoyl, or a substituted derivative thereof, and A1 is alkylene, alkenylene, cycloalkylene or cycloalkenylene; wherein X is carbonyl or hydroxymethylene or substituted derivatives thereof; wherein A2 is alkylene, alkenylene or alkylidene; wherein R2 is hydrogen or alkyl which is unsubstituted or which bears an aryl substituent, or R2 has the formula -Q2-R20 as defined below; wherein R3 is hydrogen, alkyl or a carbonyl-containing group; wherein R4 is hydrogen or alkyl which is unsubstituted or which bears a halogeno, hydroxy, amino, guanidino, carboxy, carbamoyl, mercapto, alkoxy, alkylamino, dialkylamino, cyclic amino, alkylthio, alkanoylamino, alkoxycarbonylamino, alkoxycarbonyl, alkoxycarbonyl, aryl or heterocyclyl substituent; wherein -NR5-CR6R16-Q1-R10 is an amino acid residue, R5, R6 and R16 being defined in claim 1, wherein Q1 and Q2, which may be the same or different, each is carbonyl (-CO-) or methylene (-CH2-); and wherein R10 and R20, which may be the same or different, is hydroxy, amino or a substituted derivative thereof or hydroxyamino or arylthio; or a salt thereof where appropriate; processes for their manufacture and pharmaceutical compositions containing them. The compounds are inhibitors of angiotensin converting enzyme and may be used in the treatment of hypertension.
Patent AU-654325-B2 (AU)
Title: Composition
Inventor: AUSTIN PETER WILLIAM
IPC: A61Q17/00
Filed: 1992-02-03
Granted: 1994-11-03
Abstract: A personal care formulation which contains, as an anti-microbial agent, a compound containing the structure -C(S)-N(OR)- or a salt or complex thereof, for example a 2:1 complex or salt of 3-hydroxy-4-methylthiazol-2(3H)thione and zinc. The personal care formulation may be an oil-in-water or water-in-oil emulsion such as hand lotions and emollient creams, or may be shampoos and the like. The anti-microbial agent has good activity against micro-organisms together with a low toxicity.
Patent AU-767725-B2 (AU)
Title: Modified peptides as therapeutic agents
Inventor: FEIGE ULRICH
IPC: C12P21/02
Filed: 1999-10-25
Granted: 2003-11-20
Abstract: The present invention concerns fusion of Fc domains with biologically active peptides and a process for preparing pharmaceutical agents using biologically active peptides. In this invention, pharmacologically active compounds are prepared by a process comprising: a) selecting at least one peptide that modulates the activity of a protein of interest; and b) preparing a pharmacologic agent comprising an Fc domain covalently linked to at least one amino acid of the selected peptide. Linkage to the vehicle increases the half-life of the peptide, which otherwise would be quickly degraded in vivo. The preferred vehicle is an Fc domain. The peptide is preferably selected by phage display, E. coli display, ribosome display, RNA-peptide screening, or chemical-peptide screening.
Patent AU-614279-B2 (AU)
Title: Wideband polarisation filter (duplexer)
Inventor: SCHUEGRAF EBERHARD
IPC: H01P1/161
Filed: 1988-03-23
Granted: 1991-08-29
Abstract: Measures are provided in two waveguides (7) carrying two orthogonal linear polarisations, e.g. the incorporation of an inner conductor (8) and/or of symmetrically arranged metal longitudinal webs, as a result of which its characteristic impedance can be approximated to (or, if necessary, matched to) the characteristic impedances of the two polarisation-selective rectangular waveguide arms (10, 11). In this case, two conditions must be met, namely, firstly matching the cross-section factors in the characteristic impedance equations of the waveguides to be matched to one another and secondly, matching the limit frequencies of the wave types which are to be merged. Residual reactances in the junction passages can then be matched, in a broadband manner, in a very short space without difficulties. The measures specified in the invention can be used in the case of broadband polarising junctions for satellite radio and directional radio antennas. <IMAGE>
Patent AU-600357-B2 (AU)
Title: Process for protection, reconstitution and restoration of stone buildings, monuments and similar
Inventor: WALTER RABE JUERGEN
IPC: C04B41/48
Filed: 1988-04-12
Granted: 1990-08-09
Abstract: According to a process for protection, reconstruction and restoration of stone buildings, the building is treated with a solution composed of an aliphatic isocyanate and one or more organic solvents inert to the isocyanate, and the isocyanate is then hardened in the presence of moisture. The means for carrying out the process consists of a solution of aliphatic isocyanate in one or more organic solvents inert to the isocyanate.
Patent AU-757450-B2 (AU)
Title: Methods of reducing the astringency of stannous in dentifrice compositions
Inventor: GLANDORF WILLIAM MICHAEL
IPC: A61K8/72
Filed: 1999-11-23
Granted: 2003-02-20
Abstract: Disclosed are methods for reducing the astringency of dentifrice composition containing stannous comprising administering to the subject a dentifrice composition comprising stannous. The dentifrice composition comprises stannous ions, poloxamer, and aqueous carriers. The efficacy of this dentifrice composition containing stannous will not be reduced by the poloxamer. The dentifrice composition may also contain a polyphosphate as long as the water content is limited and the stannous ion is not provided from stannous fluoride. The polyphosphate will also not reduce the efficacy of the stannous. Alternatively, the dentifrice composition may be a dual phase composition. The first dentifrice composition will contain a polyphosphate having an average chain length of about 4 or more and have a limited water content while the second dentifrice composition will contain stannous ions. In the dual phase composition, the poloxamer will be present in the first or second dentifrice compositions or both compositions. Neither the polyphosphate or the poloxamer will reduce the efficacy of the stannous.
Patent AU-671054-B2 (AU)
Title: Spraying of liquids
Inventor: JEFFERIES ANDREW
IPC: B05B5/16
Filed: 1995-06-07
Granted: 1996-08-08
Abstract: Relatively low resistivity liquids are formed into sprays under the influence of an applied electric field acting between a nozzle 10 and the surroundings (e.g. at earth potential. The liquid issues from the nozzle as a ligament which is caused to undergo necking to a smaller diameter than that of the nozzle orifice 14, thereby producing droplets with a volume median diameter less than the orifice diameter.  <IMAGE>
Patent AU-672175-B2 (AU)
Title: Antisense oligonucleotide inhibition of the ras gene
Inventor: MONIA BRETT P
IPC: C12Q1/68
Filed: 1992-06-11
Granted: 1996-09-26
Abstract: Methods are provided for preparing antisense oligonucleotides which take advantage of RNA secondary and tertiary structure and for preparing antisense oligonucleotides which specifically hybridize to regions of RNA secondary and tertiary structure by comparing the affinity of the oligonucleotide for a structured RNA target to the affinity of the oligonucleotide for a length-matched oligonucleotide complement, and selecting an oligonucleotide having an affinity for the structured target which is not less than one thousandth of its affinity for the length-matched oligonucleotide complement. Oligonucleotides are also disclosed which are specifically hybridizable with regions of H-ras RNA having secondary and tertiary structure.
Patent AU-689577-B2 (AU)
Title: New combination of a beta -receptor blocker and a local anaesthetic
Inventor: EEK ARNE TORSTEN
IPC: A61K45/06
Filed: 1995-03-24
Granted: 1998-04-02
Abstract: PCT No. PCT/SE95/00314 Sec. 371 Date Apr. 28, 1995 Sec. 102(e) Date Apr. 28, 1995 PCT Filed Apr. 24, 1995 PCT Pub. No. WO95/27511 PCT Pub. Date Oct. 19, 1995New combination of a  beta -receptor blocker, an enantiomer thereof, and a local anesthetic, administered simultaneously or sequentially, giving excellent pain relief. Also comprised in the invention is the use of a non-selective  beta -receptor blocker alone, especially a non-selective  beta -receptor blocker giving pain relief.
Patent AU-763676-B2 (AU)
Title: Power supply
Inventor: BALL DAVID A
IPC: H02J3/00
Filed: 2000-02-11
Granted: 2003-07-31
Abstract: The present invention is a power supply (10) that starts a load (20) with a heavy start-up power draw from a power grid (12) and then switches the load to a generator (22) for lower power draw operation thereby avoiding the need for a large capacity generator capable of initial start-up of the load (20). The power supply comprises a conductor (15) for connecting to a power grid, an electrical power generation device (30), an electrical power using device or load (20) and a switching mechanism (40) for 1) isolating the power grid (12) from the power generation device (30), 2) connecting the power grid conductor (15) to the electrical power using device (20) for the initial start-up of the power using device (20), and 3) connecting the power generation device (30) to the power using device (20) after initial start-up. In addition the power supply (10) can also serve as a backup source of power for multiple circuits whose total startup load exceeds the total output of the generator (30) during periods of grid power failure by selectively turning off interruptible circuit load (20) during the startup of other circuits (16) or allowing intermittent circuit loads (20) to complete their cycle and return to an off state prior to the start-up of other circuits (16).
Patent AU-734604-B2 (AU)
Title: Method of selecting an electronic module from a plurality of modules present in the interrogation field of a terminal
Inventor: KOWALSKI JACEK
IPC: G06K7/00
Filed: 1997-05-06
Granted: 2001-06-21
Abstract: A method for selecting an electronic module from a plurality of at least two modules (M1, M2, M3) capable of emitting messages simultaneously, includes the steps of sending a general query message (ACTIVALL) to the modules, and selecting (AFI, SELECT-ID) the module having responded first, the modules, on receiving a query message (ACTIVALL, ACTIV), determining a random time interval (P) and sending a responding message (ID, R) when the said time interval (P) has elapsed. A module is set in idle position (IDL) when it receives a message (MESS) before the time interval (P) preceding the sending of a response (ID, R) has elapsed. The idle position (IDL) is at least characterized by the fact that one module does not respond, subsequently, to a complementary query message (ACTIV). This invention is particularly useful for contactless smart card readers and for terminals for electronic labels.
Patent AU-605683-B2 (AU)
Title: Separation method of l-aspartyl-l-phenylalanine methyl ester
Inventor: KATOH TOSHIO
IPC: A23L27/30
Filed: 1989-03-14
Granted: 1991-01-17
Abstract: A method for separating  alpha -L-aspartyl-L-phenylalanine methyl ester ( alpha -APM) from a solution containing  alpha -APM and impurities associated with the production thereof which comprises adding a mineral acid or an organic sulfonic acid to the solution in an organic carboxylic acid or in a solvent containing an organic carboxylic acid, and isolating the pure salt of  alpha -APM which precipitates therefrom.
Patent AU-609954-B2 (AU)
Title: Dual textured food piece of enhanced stability
Inventor: LANGLER JAMES E
IPC: A23L21/12
Filed: 1989-03-16
Granted: 1991-05-09
Abstract: Disclosed are improved, dual textured food products comprising a portion of one texture and a second portion of a different texture that exhibits enhanced shelf life stability. Preferred food products are fruit snack pieces comprising a soft, supportive, fruit-containing shell portion and a second, more fluid, variably textured core portion. The shell portion can comprise a dehydrated fruit puree composition. The core portion can comprise novel w/o emulsions characterized by low fat levels and defined gelled phases.
Patent AU-718416-B2 (AU)
Title: A protective roof for bicycles or the like
Inventor: PERRET ANDRE
IPC: B62J17/08
Filed: 1997-06-10
Granted: 2000-04-13
Abstract: The invention relates to a protective roof (1) for bicycles comprising a frame (2) and a covering (3) impermeable to rainwater and/or UV-radiation. The frame (2) comprises an elastic tube (4) bent into the form of a spoon-shaped loop, the two tube ends (5a, 5b) being held in the region of the back wheel hub (6) and the end of the frame (2) being adjusted to a predetermined inclination and/or height via a tensioning cable (9) fixed in the region of the handlebar (8).
Patent AU-665394-B2 (AU)
Title: Magnetically-mounted ski rack with anti-theft means, for motor vehicles
Inventor: CORSARINI LUCIANO FABBRI
IPC: B60R9/12
Filed: 1993-02-17
Granted: 1996-01-04
Abstract: The magnetically-coupling ski rack with anti-theft means for motor vehicles in general comprises at least one panel (2) made of magnetic material which is associable with a motor vehicle and supports at least one ski supporting bracket (3) which is surmounted by an element (4) provided with lock-operated securing means (8). The peculiarity of the invention resides in the fact that it comprises an element (6) for covering the panel (2) of magnetic material which is controlled by the lock-operated securing means (8). <IMAGE>
Patent AU-676143-B2 (AU)
Title: Embedded signalling
Inventor: PREUSS ROBERT DAVID
IPC: H04B1/66
Filed: 1992-12-10
Granted: 1997-03-06
Abstract: A code signal representing a sequence of code symbols carrying digital information is generated with the frequency components of the code signal being essentially confined to a preselected signalling band lying within the bandwidth of an audio signal within which the code signal is to be embedded. The audio signal is continuously frequency analyzed over a frequency band encompassing the signalling band and the code signal is dynamically filtered as a function of the analysis thereby to provide a modified code signal with frequency components which are, at each time instant, essentially a preselected small proportion of the levels of the corresponding audio signal frequency components. Accordingly, the modified code signal can be combined with the audio signal to obtain a composite audio signal which is not readily distinguishable from the original audio signal by listening. Furthermore, the digital information can be recovered from the composite audio signal by a procedure which is essentially the compliment of that used to obtain the composite audio signal.
Patent AU-778057-B2 (AU)
Title: Non-invasive method for detecting target RNA
Inventor: IVERSEN PATRICK L
IPC: C12Q1/6883
Filed: 2000-01-28
Granted: 2004-11-11
Abstract: The present invention provides a method for targeting a particular mRNA sequence in vivo by oral administration of a morpholino antisense compound having uncharged phosphorus-containing backbone linkages. Also disclosed is a non-invasive method of detecting and quantitating the in vivo presence of RNA containing one or more selected target sequences. The method includes administering to a subject a nuclease-resistant antisense oligomer which hybridizes by Watson-Crick base pairing to a region of the target RNA with a Tm substantially greater than 37° C. The oligomer is able to complex intracellularly with target RNA, and is released from intracellular sites as a nuclease-resistant heteroduplex, which can then be measured in a body fluid sample, e.g., urine.
Patent AU-606026-B2 (AU)
Title: Needle shield
Inventor: DUFRESNE CHRISTOPHER M
IPC: A61M5/32
Filed: 1989-05-04
Granted: 1991-01-24
Abstract: An arrangement of needle shield (10) is provided which may be attached to the hub (16) of a syringe or multiple blood sample holder (12), which shield (10) is flexible and moves out of the way of the needle point (48) for insertion into the skin, and which moves automatically over the contaminated needle (36) at the instant the needle (36) is removed from the skin for shielding the user from accidental needle stick. The arrangement is in one piece and includes an elongated hood-like body (18) which surrounds the needle (36), and includes at one end a blunt front end shield (20), and at the other end a mounting ring (17) for frictionally engaging the hub (16) of a needle holder (12) or syringe. The body (18) includes an integral lock (38) which snaps over the needle (36) for holding the shield body (18) of the invention over the contaminated needle (36).
Patent AU-782265-B2 (AU)
Title: Biodegradable polymer composition
Inventor: DUNN RICHARD
IPC: A61K9/16
Filed: 2000-11-16
Granted: 2005-07-14
Abstract: A flowable composition containing a biocompatible, biodegradable, branched thermoplastic polymer is used to form solid matrices such as implants and controlled-release, drug-compositions in a body. The flowable composition with or without bioactive agent can be administered by syringe and needle to form in situ a solid matrix. Alternatively, the flowable composition can be used to form ex vivo solid biodegradable matrices such as articles, implants and devices. The articles implants and the like can then used as solid fasteners, prosthetic devices, and controlled drug compositions.
Patent AU-754808-B2 (AU)
Title: Method for preparing Monoclonal Antibody
Inventor: KUSUNOKI CHIHIRO
IPC: C07K16/00
Filed: 2000-03-30
Granted: 2002-11-28
Abstract: A significantly increased amount of a monoclonal antibody is obtained from the culture medium of recombinant hybridoma prepared by introducing genes encoding a protein identical to the immunoglobulin heavy chain polypeptide of the specific monoclonal antibody into an immortalized B cell (hybridoma) producing the monoclonal antibody.
Patent AU-771699-B2 (AU)
Title: Token-based linking
Inventor: SCHWABE JUDITH E
IPC: G06F9/445
Filed: 2000-02-02
Granted: 2004-04-01
Abstract: A system links architecture neutral code downloaded to a resource constrained computer. The code may be separated into one or more packages having one or more referenceable items. The system maps the one or more referenceable items into corresponding one or more tokens; orders the tokens to correspond to a run-time mode; downloads the packages to the resource constrained computer; and links the packages into an executable code using the ordered tokens.
Patent AU-767417-B2 (AU)
Title: System and method for fluid flow optimization in a gas-lift oil well
Inventor: BURNETT ROBERT REX
IPC: E21B47/12
Filed: 2001-01-22
Granted: 2003-11-06
Abstract: A controllable gas-lift well having controllable gas-lift valves and sensors for detecting flow regime is provided. The well uses the tubing and casing to communicate with and power the controllable valve from the surface. Ferromagnetic chokes at the surface and downhole electrically isolate the tubing from the casing. A high band-width, adaptable spread spectrum communication system is used to communicate between the controllable valve and the surface. Sensors, such as pressure, temperature, and acoustic sensors, may be provided downhole to more accurately assess downhole conditions and in particular, flow regime. Operating conditions, such as gas injection rate, back pressure on tubing and position of downhole controllable valves are varied depending on flow regime, downhole conditions, oil production, gas usage and availability, to optimize production. An Artificial Neural Network (ANN) is trained to detect Taylor flow regime using downhole acoustic sensors, plus other sensors as desired. The detection and control system and method thereof is useful in many applications involving multi-phase flow in a conduit.
Patent AU-691044-B2 (AU)
Title: Surgical suturing apparatus with loading mechanism
Inventor: TOVEY H JONATHAN
IPC: A61B17/06
Filed: 1995-11-20
Granted: 1998-05-07
Abstract: Surgical apparatus (1) for passing a surgical incision member, that is a needle (14) that is pointed at both its ends, backwards and forwards between first and second jaw elements (4, 5) at the distal end of the apparatus, the apparatu-s having at its proximal end a pair of handles (2) so connected to the jaw elements that the jaws open and close as the handles are manipulated away from and towards the longitudinal axis of the apparatus, the apparatus including a locking mechanism (26, 28) constructed and arranged to prevent unintended detachment of the needle from both the jaw elements. <IMAGE>
Patent AU-662051-B2 (AU)
Title: Arylacetamides
Inventor: GOTTSCHLICH RUDOLF
IPC: A61P25/08
Filed: 1993-05-03
Granted: 1995-08-17
Abstract: Novel arylacetamides of the formula I <IMAGE> in which Q, R<1>, R<2> and R<3> have the meaning indicated in Patent Claim 1 exhibit analgesic and neuroprotective properties and bind with high affinity to kappa receptors.
Patent AU-719935-B2 (AU)
Title: Fat-based confection
Inventor: DESTEPHEN STEPHEN J
IPC: A23P20/00
Filed: 1997-10-08
Granted: 2000-05-18
Abstract: The present invention relates to a method for increasing the solidification rate of a fat-based confection and to a fat-based confection product wherein the improvement comprises 0.1 to 2.0 % insoluble fiber by weight effective for increasing the rate of solidification of the product. <IMAGE>