baber/WOPTO huggingface dataset:
Patent FI-951249-A (FI)
Inventor: BERNOTAS RONALD CHARLES
IPC: C07D333/56
Filed: 1995-03-16
Abstract: The present invention is directed to a new class of 2-optionally substituted-4-piperazine-benzothiophene derivatives of the formula     <IMAGE>  Formula I  in which Y is represented by hydrogen or C1-3 alkyl; R is represented by a substituent selected from the group consisting of hydrogen, C1-4 alkyl, C1-4 alkoxy, halogen, -CF3, -OCF3, and -OH; R1 is represented by hydrogen, cycloalkyl, C1-6 alkyl, phenyl optionally substituted, phenylalkyl, or phenylamidoalkyl; X is represented by hydrogen, -(CH2)nX1, CH=CHX1 or CHX2-(CH2)q -CH3; n is an integer from 0-2; q is either the integer 0 or 1; X1 is represented by -OH-,-OR2, -NR2R3, -CO2R2, -CONR2R3, -CN, or -COR2; R2 and R3 are each independently represented by hydrogen, C1-4 alkyl, phenyl optionally substituted, phenylalkyl, or R2 and R3 together form a (CH2)m cycloalkyl, where m=2- 6; X2 is -OR4 or -NR4R5 in which R4 and R5 are each independently hydrogen or C1-4 alkyl; and the pharmaceutically acceptable addition salts thereof; with the proviso that when n is O or X is -CH=CHX1, then X1 is not OH, OR2, or NR2R3; that are serotonin 5HT1A and 5HT1D receptor agents.
Patent FI-964263-A (FI)
Inventor: ESSENPREIS MATTHIAS
IPC: A61B5/00
Filed: 1996-10-23
Abstract: PCT No. PCT/DE95/00573 Sec. 371 Date Oct. 10, 1995 Sec. 102(e) Date Oct. 10, 1995 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30368 PCT Pub. Date Nov. 16, 1995A method for the analytical determination of the glucose concentration in a biological sample. In a detection step, light is irradiated into the sample and the light emerging therefrom after interaction with the sample emerges therefrom is detected in order to measure a physical light property affected by said interaction. The glucose concentration is determined from this measurement in an evaluation step. To provide a method for determining glucose in reagent-free and non-invasive manner, the invention proposes that a portion of the light emitted by the light source be guided along a reference light path of defined optical path length to the photodetector, that the total measuring light path also has a defined optical length and that the measuring light path after it has traversed the sample is so combined with the reference light path that the measuring light and the reference light interfere with each other. The photodetector measures an interference signal used in the evaluation step to determine the glucose concentration.
Patent GB-268464-A (GB)
Title: Improvements relating to grabs, excavators and like apparatus
IPC: E02F3/413
Filed: 1926-01-13
Abstract: 268,464. Priestman, S. H. Jan. 13, 1926. Rod couplings.-Telescopic guide-members a, b connecting the top cross-bar g and the lower cross-beam h of a grab, are provided with a third guide member c which gives additional lateral support to the members a, b when fully extended, the guide members being adapted to form dashpots for cushioning the opening of the grab. As shown in Fig. 2, the member c is provided with a piston head d and is a good sliding fit in the members a, b. It is connected by a chain f to the cross-bar g so as to take up a suitable position when the guides are extended. In modifications, the chain is replaced by a headed rod o, Fig. 4, the member c is replaced by a rod r, Fig. 6, working through a stuffing-box s in the member b and attached to the lower end of the member a, or the rod c works in an inner tube t in the member a, Fig. 8.
Patent GB-671346-A (GB)
Title: Process for preparing methin dyes containing a 3-aryl-4-thiazolidone nucleus and photographic emulsions containing them
IPC: C09B23/04
Filed: 1949-01-13
Abstract: A methine dye of the general formula <FORM:0671346/IV (c)/1> wherein Z represents the atoms necessary to complete the nucleus of a benzthiazole, benzselenazole, a - or b -naphthathiazole, quinoline, thiazoline, thiazole, or 3 : 3-dimethylindolenine, R is alkyl (or where Z completes a benzthiazole or thiazoline nucleus, alkyl or aryl), R2 is aryl, n is 0 or 1, and X is a halogen atom, is prepared by condensing a halogeno ester of the general formula X-CH2-CO-O-R1 wherein R1 is alkyl or aryl, with a compound of the general formula <FORM:0671346/IV (c)/2>  2 - [(2 - Benzthiazolyl ethiodide) - methylene]-3 - phenyl - 4 - thiazolidone is prepared by heating together 2-(2-anilino-2-thioethylidene)-3-ethylbenzthiazoline and ethyl bromoacetate, dissolving the product in hot methanol, and adding aqueous potassium iodide.  The corresponding ethochloride is prepared by using ethyl chloracetate, or by treating the ethiodide with silver chloride.  2-[(2-b -Naphthathiazolyl ethobromide) - methylene] - 3 - phenyl - 4 - thiazolidone and the corresponding ethochloride, 2 - [(2 - quinolyl ethoperchlorate) - methylene] - 3-phenyl - 4 - thiazolidone, 2 - [(2 - benzselenazolyl ethiodide) - methylene] - 3 - phenyl - 4 - thiazolidone, 2 - {[2 - (4 - methylthiazolyl) - ethiodide]-methylene} - 3 - phenyl - 4 - thiazolidone, and 2-[(4 - quinolyl ethoperchlorate) - methylene] - 3-phenyl-4-thiazolidone are similarly prepared.  A dye of the general formula <FORM:0671346/IV (c)/3> wherein R6 and R7 each represent an alkyl group, is prepared by condensing a dye of the first general formula with a p-dialkylaminobenzaldehyde.  2 - [(Benthiazolyl ethochloride) - methylene]-5- p - dimethylaminobenzylidene - 3 - phenyl - 4-thiazolidone is prepared by refluxing together 2- [(2 - benzthiazolyl ethochloride) - methylene] - 3 - phenyl - 4 - thiazolidone and p-dimethylaminobenzaldehyde in ethanol containing piperidine. 5-p-Dimethylaminobenzylidene - 2 - [(2 - b  - naphthathiazolyl ethochloride)-methylene] - 3 - phenyl - 4 - thiazolidone is similarly prepared.  Dyes are also prepared by condensing dyes of the first general formula with alkyl orthoformates.  In examples, 2-[(2-benzthiazolyl ethobromide) - methylene] - 3 - phenyl - 4-thiazolidone and ethyl orthoformate are refluxed together in pyridine, and a concentrated solution of the product is treated with aqueous potassium iodide, and 2-[(2-b -naphthathiazolyl ethobromide) - methylene] - 3 - phenyl - 4-thiazolidone and ethyl orthoformate are refluxed together in pyridine containing triethylamine, and a concentrated solution of the product is treated with aqueous potassium iodide.  Specifications 533,238, 546,705, 551,331, 551,824, 566,010, 618,073, 646,896, 646,900, 647,542 and 649,725 are referred to.
Patent GB-495525-A (GB)
Title: Improvements in weighing scales
IPC: G01G1/18
Filed: 1938-01-12
Abstract: 495,525. Weighing-apparatus. THORNTON, A. A. (Triner Scale & Manufacturing Co.) Jan. 12, 1938, No. 1041. [Class 143] Platform machines; bearings.-A weighing scale has a platform supported by a system of levers of which at least one is supported on a member which extends crosswise of the base housing, the cross-member comprising at least at its ends a pair of parallel bars 29, Fig. 1, secured to the side walls of the housing (for example by brazing) and spaced apart to receive fillers 32, Figs. 4, 6, the levers being supported on the cross-member at each of two points by a knife-edge member 38 engaging a groove in a self-aligning bearing block 34 which is pivoted by a pin 35 on upward extensions of the fillers 32, one end of the knife-edge member being sharpened to a point and, by means such as a clip 41, maintained in bearing contact with a hard metal member 42 located in a recess in an adjustable screw 44. Casings.-The side walls of the housing are hollow and comprise Z-shaped plates 21, 22, Fig. 4, reinforced by a plate 28 and united by brazing. The ends of the fillers 32 extend through the plates 28, 22.
Patent GB-449332-A (GB)
Title: An annealing pot for clean annealing band iron, wire, metal sheet, drawn and pressed parts
IPC: C21D1/74
Filed: 1935-01-11
Abstract: 449,332. Annealing pots. GRœNEWALD, H., Hilchenbach, Westphalia, Germany. Jan. 11, 1935, No. 1055. Convention date, June 19, 1934. [Class 72] In an annealing-pot b provided with a hollow lid c, a pipe d for accommodating an electric heating body e extends into the body of the pot and is secured, e.g. welded, in the bottom of the lid c in a gas-tight manner, the pipe being closed at the bottom and open at the top. A thermo-regulating device f is also arranged in the heating body e. The pot b is suspended within the furnace a which may be heated by burners g or electrically. After the annealing operation, the pot b is withdrawn from the furnace and the heating body withdrawn from the pipe d which is then open to the air, the cooling of the material h in the pot being thus accelerated.
Patent GB-598904-A (GB)
Title: Improvements in or relating to alloy steel and articles made therefrom
IPC: C22C38/50
Filed: 1945-01-12
Abstract: An alloy steel having high strength at elevated temperatures consists of the following percentages :-.15 to .35 C., .40 to 3.00 Mn, .40 to 2.00 Si, 18.00 to 23.00 Cr, 8.00 to 20.00 Ni, .75 to 2.00 W., .75 to 2.00 Mo, .15 to 1.50 Nb, .10 to 1.00 Ti, with or without up to .04 of S and up to .04 of P, the balance being iron which may contain the usual impurities.  In an example the respective elements are :-.28 C, .75 Mn, .55 Si, .19 Cr, 9Ni, 1.25 W, 1.25 Mo, .30 Nb and .25 Ti.  The Nb content may include 8 per cent of Ta.
Patent GB-1376562-A (GB)
Title: Process for producing citric acid and/or isocitric acid
IPC: C12P7/48
Filed: 1973-01-10
Abstract: 1376562 Citric acid KYOWA HAKKO KOGYO CO Ltd 10 Jan 1973 [13 Jan 1972] 1356/73 Heading C2C Citric acid is prepared by the aerobic fermentation of acetic acid or the salt or ester thereof by Candida zeylanoides ATCC 20347. Nitrogen sources may be present and a temperature of 15 to 40 C. and pH 3 to 7 maintained. Isocitric acid is also prepared and the acids may be isolated as sodium or calcium salts.
Patent GB-668382-A (GB)
Title: Improvements in or relating to the manufacture of toy balloons and like articles made by dipping
IPC: B29C37/00
Filed: 1949-01-18
Abstract: 668.382. Moulding by dipping. LATEX INDUSTRIES, Ltd., and LANDAU, L. Jan. 9,1950 [Jan 18, 1949; Feb. 24, 1949], Nos. 1430/49 and 5088/49. Class 87(ii). Rubber balloons &c. are stripped from the formers on which they are made by dipping, by passing the formers 10 between two resilient rubber discs or rollers 14, 15 rotating in opposite directions on substantially parallel axes. Air and water from nozzles 12, 13 are first injected behind the beaded edge 16 of the balloon 11 before the former 10 is passed between the two discs 14, 15. The discs are preferably made of cellular or sponge rubber and are yieldably mounted, e.g. by a weight and pulley system, to bear resiliently on the balloon. In an alternative method, Fig. 2a, the former 10 is first positioned so that the beaded edge 16 contacts the rotating discs 14, 15. The former is then raised and the balloon rolled off the former.
Patent GB-137866-A (GB)
Title: Improvements in loading mechanism for fire-arms
IPC: F41A9/18
Filed: 1920-01-16
Abstract: 137,866. Rheinische Metallwaarenund Maschinenfabrik. March 13, 1918, [Convention date]. Void [Published under Sect. 91 of the Act]. Machine guns.-Consists of cartridge-feed mechanism comprising means for drawing a cartridge from a belt or magazine into a pivoted carrier adapted to convey it into the loading position. In the construction shown, the cartridge is drawn from the belt or magazine into a conveyer e by a claw d mounted on a slide c which reciprocates with the breech-block sleeve a. The conveyer e is pivoted at f and is oscillated by a pin i on the slide c engaging a two-way cam slot h h<1> in a plate fixed to the conveyer. The cartridge-holding part of the conveyer is a tube having a slot g, Fig. 3, at the bottom so that, when the conveyer is lowered to the loading position, the sleeve a can engage the cartridge and push it into the barrel.
Patent GB-302070-A (GB)
Title: Improvements in methods and apparatus for making carbon dioxide snow
IPC: C01B32/55
Filed: 1928-01-17
Abstract: 302,070. Thurston, A. P., (Dryice Corporation of America). Jan. 17, 1928. Solidifying.-Carbon dioxide is made from the compressed liquid by releasing the pressure, its liquid being cooled below its equilibrium temperature at the existing pressure. Compressed liquid carbon dioxide is cooled in a coil 2 by a circulation to about zero Fahr., and its pressure increased by a compressor 7 to 1100-1700 lb. per sq. in. It is cooled in a cooler 9 by gas escaping from the snow chamber 10 into which it expands from a pressure reservoir 15 through a nozzle 17 shaped as shown in Fig. 2. The snow chamber is long and of large volume, and is formed by a metal vessel 10 surrounded by an insulated vessel 21, the waste gas passing around the inner vessel. The snow is removed through a door 25.
Patent GB-157851-A (GB)
Title: Process for tanning hides
IPC: C14C3/20
Filed: 1921-01-10
Abstract: Alkaline-earth salts of synthetic tanning-agents of the kinds described in Specification 156,254, are prepared for use in tanning. According to an example, a mixture of naphthalene and phenol is sulphonated and condensed with formaldehyde solution, the product is diluted, neutralized with lime, and filtered, and the solution used for tanning.  The products may be employed alone or mixed with other tanning-agents.
Patent GB-651797-A (GB)
Title: Preparation of 4-vinylcyclohexene dioxide
IPC: C07D303/04
Filed: 1948-01-19
Abstract: 4-Vinyl cyclohexene dioxide is prepared by dehydrohalogenating dichlorhydrins of 4-vinyl cyclohexene by treating with the hydroxide or carbonate of an alkali or alkaline earth metal, in an aqueous medium.  Any temperature from the freezing point to the boiling point of the reaction mixture may be used but the preferred temperatures are 25 DEG  C. and lower.  The resulting dioxide may be isolated by extraction with a solvent for the dioxide which is unattacked by the oxide, e.g. chlorinated hydrocarbons, ether and aliphatic and aromatic hydrocarbons.  The dichlorhydrins may be prepared as described in Specification 648,456.  The following are representative of numerous examples: (1) a hypochlorite solution obtained by passing chlorine into an aqueous suspension of calcium carbonate followed by filtration, is added over a period to a stirred suspension of 4-vinyl cyclohexene in water at below 10 DEG  C. and the resulting dichlorhydrins are isoated by ethereal extraction; the dichlorhydrins are added to aqueous sodium hydroxide with stirring at 25 DEG  C. and the resulting dioxide isolated by extraction of the mixture with carbon tetrachloride; (4) chlorine is bubbled through an aqueous solution of sodium hydroxide at 3 DEG  C. and to the resulting solution of hypochlorite is added 4-vinyl cyclohexene and then aqueous sulphuric acid sufficient to liberate most of the hypochlorous acid from the hypochlorite; aqueous sodium hydroxide is now added and sufficient sodium sulphite to decompose the excess hypochlorite, and the 4-vinyl cyclohexene dioxide produced is extracted as before; (8) chlorine gas is bubbled through aqueous sodium hydroxide at 3 DEG  C., the resulting solution added slowly to a dispersion of 4-vinyl cyclohexene in aqueous sulphuric acid at not above 10 DEG  C., then aqueous sodium hydroxide is added; the mixture is extracted with carbon tetrachloride and the extract distilled at 5 mm. pressure to isolate the dioxide, quantities of 4-vinyl cyclohexene monoxide appearing in the fore-runnings; (9) a hypochlorite solution obtained as in (8) is added slowly with vigorous stirring to a suspension of 4-vinyl cyclohexene in aqueous sulphuric acid at below 10 DEG  C., the addition being stopped when test shows that hypochlorous acid is not rapidly taken up; at this stage an oil appears containing monochlorhydrins, so a solvent, ethylene dichloride, is added and addition of the hypochlorite continued; aqueous sodium hydroxide is then added and the dioxide is recovered from the ethylene dichloride layer; (11) chlorine is passed into an aqueous suspension of 4-vinyl cyclohexene until a positive test for hypochlorite persists, whereupon excess hypochlorite is decomposed by addition of sodium sulphite, and the dichlorhydrins converted to dioxide by addition of sodium hydroxide.  The Specification as open to inspection under Sect. 91 refers to the preparation of 4-vinyl cyclohexene dioxide from the dichlorhydrins by dehydrohalogenation in general.  This subject-matter does not appear in the Specification as accepted.
Patent GB-711923-A (GB)
Title: Improvements in contrivances for rotating and tilting objects
IPC: B23K37/04
Filed: 1952-01-21
Abstract: 711,923. Uniting by fusion. YATES, H. Dec. 12, 1952 [Jan. 21, 1952], No. 1651/52. Class 83 (4). [Also in Group XXX] In a device for rotating and tilting objects, e.g. during welding, having a rotatable table mounted on a support tiltable about a. horizontal axis, a lever arm substantially parallel with and beneath the table and fixed to the support is pivotally connected by a rod to a trolley displaceabte by a' hut andscrew device along a guide inclined from beneath the table upwardly in the opposite direction to that in which the lever arm extends when the table - is horizontal. A rotatable table a on which a workpiece may be secured is supported in a Babbitt metal bearing b welded to levers c, /, which form an arm located between upstanding' plates d and pivoted on a horizontal shaft e journalled in the plates. A rod i is pivoted to the levers c and to a lug j<SP>1</SP> on a trolley. j movable along an inclined guide m formed by two spaced apart channel sections welded together and positioned between the plates d. Rollers j<SP>2</SP> on the trol!ey engage the opposed flanges of the channels and a nut k on the trollev is engaged by a screw I between the channels 'rotated by a wheel o, Rotation of the wheel o, moves the trolley in the guide and through the rod i the table is tilted about the shaft e. A motor p drives the table a through a belt q, worm, pinion s and spur wheel t. Channels g, g' welded to the plates d form feet for the device. A ball bearing may replace the Babbitt metal bearing.
Patent GB-137911-A (GB)
Title: Improvements in or relating to the preparation of timber for impregnation
IPC: B27M1/00
Filed: 1919-01-22
Abstract: 137,911. Coderre, J. A., and Kynoch, W. G. Jan. 22, 1919. Incising to facilitate impregnation with liquids. -The wood is passed between a series of vertical and horizontal rollers 16, 27, 28 provided with projecting blades 50 whereby incisions are formed by pressing aside the fibres without cutting them, the depth of the incisions increasing from their ends to the centre. The rollers are adjustable by screws 34 and are supported by springs 32, whereby they yield to irregularities in the wood. The blades 50 are supported by sliding blocks 49 inserted into recesses in the rollers, and the blocks are adjustable by screws 52. In a modified arrangement the blades are carried by screw-threaded blocks and are adjustable in the blocks by screws such as 52.
Patent GB-816581-A (GB)
Title: Process for the preparation of silica sols
IPC: C01B33/141
Filed: 1956-01-18
Abstract: An aqueous silica sol, of concentration greater than 15 per cent by weight of silica and average diameter 710 millimicrons, is obtained by heating above 50 DEG  C. an aqueous, alkali-metal silicate solution, preferably Na2SiO3 (10 per cent SiO2); electrolysing the solution to remove alkali metal ions and oxygen using a mercury cathode until the weight ratio silica: alkali metal oxide is greater than 50:1, preferably 130:1 to 200:1, and removing water if desired to concentrate the sol. During electrolysis when alkali metal forms an amalgam with the cathode, alkali metal silicate may be added to maintain the desired concentrations.  Specifications 645,703, 667,154 and U.S.A.  Specifications 1,562,940, 1,853,420 and 2,375,738 are referred to.
Patent GB-936739-A (GB)
Title: Automatic record changer
IPC: G11B3/085
Filed: 1961-01-16
Abstract: 936,739. Gramophone record changers. THORENS S.A. Jan. 16, 1961 [Jan. 20, 1960], No. 1777/61. Class 40 (2). A gramophone pick-up arm 43 has a record-gauging feeler 73 and is lowered as record supports 4, 5 are being withdrawn into a centre-post 2. After the record has fully dropped, further withdrawal of the pick-up supporting means, Fig. 6, allows a second feeler 74 to contact the record surface, whereupon both feelers are withdrawn, allowing the stylus to enter the lead-in groove. The cycle for each record includes contacting a pick-up rest 83, which contacts a member 80 to reset the feelers for the next record. The centre-post has symmetrical retracting supports 4, 5 and an expandable resilient washer 22 to retain the lowestbut-one record when the lowest is being lowered. To prevent random tilting of stored records from affecting the changer operation, the centrepost support nearest the pick-up feelers is arranged to tilt that side of the record slightly upwardly, d<11>5, Fig. 7, as the supports are retracted.
Patent GB-1413572-A (GB)
Title: Device for use in teaching first aid
IPC: G09B23/28
Filed: 1973-01-12
Abstract: 1413572 Training in artificial respiration A S LAERDAL 12 Jan 1973 [12 July 1972] 1853/ 73 Heading A5T [Also in Division G5] A device for use. in teaching artificial respiration comprises a panel 1; a first planar element 2 showing a side view of a human head except for the lower lip and marked to illustrate the tongue 12, the element 2 being rotatably mounted on the panel 1 by means of a pin 17; and a second planar element 3 shaped in accordance with an associated neck 13 and the lower lip and marked to illustrate the windpipe 14; the element 3 underlying the element 2 which, apart from its markings, is transparent, and being rotatably mounted on the panel 1 by virtue of a slot 18 engaged by the pin 17, the element 3 further being pivoted to the element 2. by means of a pin 19. The arrangement is such that the elements are relatively movable between a first position, as shown, in which the mouth appears closed and the windpipe to be blocked by the tongue, and a second position, Fig. 1b (not shown), in which the mouth and windpipe appear open. Representations 23 of hands show where pressure should be applied to the head to free the windpipe which step, in a real situation, is necessary before artificial respiration becomes possible. The device may be combined with a further device for use in demonstrating the correct positioning of an injured person and comprising a panel (1') Figs. 2a to 2c (not shown) bearing a pivoted planar element shaped in accordance with a side view of substantially the whole of a human body. The devices may be made of paper, cardboard, or plastics material, and the panel 1 (1') may be pages of a book for teaching various first aid measures.
Patent GB-1029321-A (GB)
Title: Improvements in or relating to brake arrangements for spinning or twisting spindles
Inventor: BARTLING GERHARD
IPC: D01H7/22
Filed: 1964-01-16
Abstract: An arrangement for braking a spinning spindle of which driving parts are enclosed in a housing, comprises a flexible member secured in an opening in the housing, which member is pressed by hand to apply the brake.  A plunger is fastened to the member, and adjacent to it is an arm of a two-armed lever of which the other arm bears on a fixed part.  When the member is pressed, the plunger is moved to raise the second arm of the lever, and to raise brake blocks to which it is pivoted, beneath the wharve to brake it.  In another form, the plunger terminates in a shoe which directly engages the wharve when the member is pressed.