baber/WOPTO huggingface dataset:
Patent AU-2020409887-A1 (AU)
Title: Stable and highly concentrated formulation of the antibody nimotuzumab
Inventor: HERNÁNDEZ TERRERO YAIKO SADDAN
IPC: A61P1/00
Filed: 2020-12-10
Abstract: The present invention relates to the fields of biotechnology and medicine and describes high-concentration pharmaceutical formulations comprising the humanised monoclonal antibody nimotuzumab in a concentration range between 50 and 200 mg/mL. The low viscosity values of these solutions enable them to be used subcutaneously or intramuscularly in cancer treatments. These formulations are stable in both liquid and freeze-dried forms.
Patent WO-2022061400-A1 (WO)
Inventor: BLANK SAMUEL
IPC: B65D25/00
Filed: 2021-09-21
Abstract: A container unit is provided having a base and a side wall around the base. The side wall comprises a rim having an outer peripheral edge, and at least two protruding flanges spaced from one another. Each protruding flange is configured to extend laterally from the side wall and upwardly relative to the rim to define an edge receiving portion. The container unit is configured to interlock with a substantially similar or substantially identical container unit to thereby define an enclosed container. The enclosed container is assemblable by bringing the rims of two container units into contact with one another, the outer peripheral edge of each rim being received into the edge receiving portion of a respective protruding flange. Upon rotation of one of the container units relative to the other of the container units the pairs of protruding flanges align and mate and optionally interlock with one another which may prevent separation of the two bowl shaped units forming the enclosed container. The enclosed container is dissassemblable by reversing the rotation of one of the container units relative to other of the container units thereby causing the container units to be separated.
Patent WO-2022133550-A1 (WO)
Title: Conduit connector with flow-regulating vent for patient interface
Inventor: VARMA SANGADI NOOKARAJESH
IPC: A61M16/20
Filed: 2021-12-23
Abstract: A patient interface may include a plenum chamber pressurisable to a therapeutic pressure by a flow of air for breathing by a patient; a seal-forming structure connected to the plenum chamber, the seal-forming structure being constructed and arranged to seal with a region of the patient's face that at least partly surrounds an entrance to the patient's airways; a positioning and stabilising structure configured to hold the seal-forming structure in a therapeutically effective position on the patient's head; a first vent configured to allow exhaled gases to pass to ambient independent of therapeutic pressure and throughout the patient's respiratory cycle; and a second vent configured to reduce a vent flow of exhaled gases therethrough as the therapeutic pressure increases.
Patent AU-2021200731-A1 (AU)
Title: Pro-drug peptide with improved pharmaceutical properties
Inventor: ZIMMER ROBERT H
IPC: A61K38/26
Filed: 2021-02-04
Abstract: The present disclosure relates to a pro-drug peptide, or a salt thereof, having improvement for 
at least one biological property relative to a parent peptide or peptidomimetic, wherein the 
biological property is selected from the group consisting of therapeutic index, stability, 
solubility, toxicity, adsorption, and pre-systemic metabolism. The pro-drug peptide comprising 
the following structure: Z-pep, wherein: pep is the parent peptide or peptidomimetic; Z is a 
sequence of n amino acids, Z is cleaved in vivo releasing pep; n > 2 amino acids. The present 
disclosure also relates to methods of making and using the pro-drug peptide of the present 
disclosure. For example, the present disclosure describes a pro-drug peptide that may be used 
to prevent, treat, or ameliorate at least one symptom of hypoglycemia or a hypoglycemia
related disease or disorder.
Patent AU-2021202701-A1 (AU)
Title: Position information processing system and position information processing device
Inventor: SHIBASAKI RYOSUKE
IPC: G01S19/37
Filed: 2021-04-30
Abstract: The present invention sequentially and repeatedly 
accepts a plurality of types of information that can 
change with time, including position information 
obtained using a satellite signal, and correlates and 
records the accepted plurality of types of information 
with time information.
Patent AU-2021204025-A1 (AU)
Title: Food preparation device with parallel electrical cold conductors
Inventor: SCHMITZ KEVIN
IPC: F24C7/06
Filed: 2021-06-17
Abstract: The invention relates to food preparation apparatus 1 with an electrical heating device 
comprising at least two electrical PTC thermistors 5, 6, 7, 8 for heating a food in a food 
5 preparation space, wherein the electrical PTC thermistors 5, 6, 7, 8 are electrically connected 
in parallel. The parallel-connected PTC thermistors 5, 6, 7, 8 are electrically connected to 
each other by one or more electrical bridges 11 to 17.  
Through the invention, local heating during the preparation of a food may be avoided.  
10
1/5 
3 4 
9 10 
18, 
11 
3 4 
11 17 
1314 
FIG. 2
Patent AU-2021209962-A1 (AU)
Title: Heterocyclic compounds and uses thereof
Inventor: ESPOSITO MARK
IPC: A61K31/4709
Filed: 2021-01-25
Abstract: Provided herein are novel heterocyclic compounds, for example, compounds having Formula I, I-P, II, lI-P, or III. Also provided herein are pharmaceutical compositions comprising the compounds and methods of using the same, for example, in inhibiting aldehyde dehydrogenases and/or for treating various cancers, cancer metastasis, type 2 diabetes, pulmonary arterial hypertension (PAH) or neointimal hyperplasia (NIH).
Patent AU-2021215893-A1 (AU)
Title: CHO cell expressing IL-15 heterodimers
Inventor: GABRIEL RICHARD
IPC: C07K14/54
Filed: 2021-01-29
Abstract: The present invention relates to IL-15/IL-15Rα heterodimer produced in a CHO cell line, and method of producing the heterodimer and method of treatment using the heterodimer.
Patent AU-2021216134-A1 (AU)
Title: Methods of increasing maturation of heart, pancreatic beta-cells, and neurons
Inventor: NAHMIAS YAAKOV
IPC: C12N5/0735
Filed: 2021-02-09
Abstract: Provided are methods of generating a metabolically mature human cell selected from the group consisting of a cardiomyocyte, a pancreatic beta cell, and a neuronal cell, using an effective concentration of a conjugated fatty acid and optionally a non- conjugated fatty acid selected from the group consisting of: a monounsaturated omega-9 fatty acid, palmitic acid, linoleic acid (LA) and a short chain fatty acid. Also provided are isolated populations of metabolically mature human cells, and methods and kits using same for selecting a compound for toxicity to the cells.
Patent AU-2021225200-A1 (AU)
Title: Nanoparticle compositions and methods for immunotherapy
Inventor: MCCREEDY BRUCE
IPC: A61K9/14
Filed: 2021-09-02
Abstract: The present invention provides compositions and methods for immunotherapy, which include 
shelf-stable pharmaceutical compositions for inducing antigen-specific T cells. Such 
compositions are employed as components of an artificial antigen presenting cell (aAPC), to 
provide a patient with complexes for presentation of an antigen (e.g., a tumor antigen) and/or 
a T cell co-stimulatory molecule.
Patent AU-2021231083-A1 (AU)
Title: Compositions and methods for treatment of cancer
Inventor: LOBB ROY
IPC: C07K16/30
Filed: 2021-03-08
Abstract: Compositions, e.g., compositions comprising protein therapeutics, and methods of using such compositions for treating cancer are described.
Patent AU-2021256864-A1 (AU)
Title: Combination of a sheath and a knife
Inventor: PLICHON STÉPHANE
IPC: B24D15/08
Filed: 2021-03-05
Abstract: Disclosed is a combination of a sharpening sheath (1) and a knife (2) comprising a blade (20) intended to be reconditioned in the sheath (1), wherein the sheath (1) comprises a cavity (40) for receiving the blade (20) and an access opening (10) at one end of the cavity (40), the sheath (1) comprising, in the lower portion thereof, a device for receiving the cutting edge of the blade (20), characterized in that the sheath (1) has, in the upper portion thereof, a locking element (55) which cooperates with a safety element (22) provided on the back of the blade (20) to longitudinally immobilize the knife (2) in the sheath (1), and in that the device for receiving the cutting edge of the blade (20) is carried by an arm (7) rotatably mounted in the sheath (1), the sheath (1) comprising return means (8) acting on the arm (7) to return the device for receiving the cutting edge of the blade (20) towards the locking element (55).
Patent AU-2021257975-A1 (AU)
Title: Sonar display features
Inventor: NEUMANN KARL THOMAS
IPC: G01S15/88
Filed: 2021-10-27
Abstract: A system for analysis of sonar data is provided comprising sonar transducer assembl(ies), 
processor(s), and a memory. The memory includes computer program code that is configured to, 
when executed, cause processor(s) to receive sonar data, where an object is represented within 
sonar data, and additional data from a data source other than the sonar transducer assembl(ies).  
The processor(s) further determine object characteristic(s) of the object using sonar data and 
additional data, and determine an estimated object-type for the object represented within sonar 
data using the object characteristic(s). The processor(s) further generate a sonar image based on 
sonar data, cause display of the sonar image, and cause provision of an indication of the 
estimated object-type so that the indication of the estimated object-type is correlated to the object 
representation in the sonar image.  
46 
Atty Dkt: 48379/09478
Receive Sonar Data 
1704 
Receive Additional Data 
1706 
Determine Object Characteristic(s) of 
an Object Using the Sonar Data and 
the Additional Data 
1708 
Determine an Estimated Object-Type 
1710 
Generate a Sonar Image Based on the 
Sonar Data 
1712 
Cause Presentation of Sonar Data 
1736 
Cause Presentation of an Indication of 
a First Characteristic of the Estimated 
Object-Type 
1738 
Receive an Indicator that the User has 
Selected the Representation of the 
Object 
1740 
Cause Presentation of an Indication of 
FIv171 a Second Characteristic of the 
Estimated Object-Type
Patent AU-2021267584-A1 (AU)
Title: System and apparatus for nanopore single molecule sequencing
Inventor: LI SHIFENG
IPC: H03M1/18
Filed: 2021-04-27
Abstract: An integrated circuit for controlling a sensor chip capable of sensing various materials includes a plurality of amplifier clusters, a plurality of analog multiplexers, and at least one analog-to-digital converter coupled the analog multiplexers and configured to generate digital code values representative of electrical signals. Each of the amplifier clusters include four amplifiers, each amplifier has a first input coupled to a sensor of the sensor chip, and a second input coupled to a programmable voltage reference. Each one of the analog multiplexers is coupled to one of the amplifier clusters and configured to selectively pass through an electrical signal to the at least one analog-to-digital converter.
Patent AU-2021267679-A1 (AU)
Title: Two-component composition for forming an injectable or pumpable organo-mineral material, and associated sealing methods and uses
Inventor: KOELLSCH DIDIER
IPC: C09K17/46
Filed: 2021-05-04
Abstract: The present invention relates to a two-component composition consisting of a component A intended to be mixed, in situ, with a component B in order to form an injectable or pumpable organo-mineral compound, in particular for injection-sealing dynamic anchor bolts, comprising at least one alkali metal silicate, at least one polyisocyanate derivative and at least one cement. The component A further contains at least one polyol having a molecular mass of between 50 and 200 g/mol, at least one polymerisation catalyst comprising at least one polar function and at least one gelling agent and the component B further comprises at least one suitable plasticiser, the final mixture of the components A and B leading to the formation of an organo-mineral material having a compressive strength at 10% deformation of at least 17 MPa according to ISO 604 and a shear strength of at least 7 MPa, according to AFTM D732, for setting times of between 20 seconds and 15 minutes at 20°C. It also relates to a method for using a composition according to the invention, the method being characterised in that the components A and B are injected using positive displacement pumps into an anchoring hole. The invention is used in the field of anchor bolt sealing.
Patent AU-2021282386-A1 (AU)
Title: Method for manufacturing coal-based geopolymer foam including silica fume
Inventor: LEE KEEYUN
IPC: C04B38/10
Filed: 2021-03-25
Abstract: Disclosed herein are a lightweight geopolymer foam with low thermal 
conductivity and a manufacturing method therefor in which coal bottom ash and 
fly ash are used together as materials for the geopolymer foam and silica fume 
is added to a mixed solution of an alkali activator and sodium hydroxide. The 
geopolymer foam can be utilized for improving insulation performance and safety 
for a structure constructed with eco-friendly cement.
Patent AU-2021283960-A1 (AU)
Title: Self-sealing container
Inventor: COLLIS RONALD
IPC: B65D77/32
Filed: 2021-06-04
Abstract: A self-sealing container is formed from a blank comprising panels and end flaps connected along fold lines with the panels and the end flaps being foldable along the fold lines to form the container. The container includes a securing feature that seals the container in a closed position, with the securing feature providing a visual indication of opening if the container is opened from the closed position. After the container is opened, the securing feature provides a closure feature that allows the container to be closed.
Patent AU-2021292116-A1 (AU)
Title: Stable formulation for recombinant anti-PD-1 monoclonal antibody
Inventor: HU PING
IPC: C07K16/28
Filed: 2021-06-17
Abstract: Provided is a stable formulation for a recombinant monoclonal antibody, consisting of a recombinant anti-PD-1 monoclonal antibody, a buffer, an osmotic pressure regulator, a stabilizer, and a surfactant. The pharmaceutical formulation may enhance the stability of the antibody, and prolongs a validity period of the antibody in aqueous formulations.
Patent AU-2021320384-A1 (AU)
Title: Compounds and methods for modulating SCN2A
Inventor: JAFAR-NEJAD PAYMAAN
IPC: C12N15/113
Filed: 2021-08-06
Abstract: Provided are compounds, methods, and pharmaceutical compositions for reducing the amount or activity of SCN2A RNA in a cell or subject, and in certain instances reducing the amount of SCN2A protein in a cell or subject. Such compounds, methods, and pharmaceutical compositions are useful to ameliorate at least one symptom or hallmark of a disease or disorder associated with a voltage-gated sodium channel protein, such as, for example, a Developmental and Epileptic Encephalopathy, an intellectual disability, or an autism spectmm disorder. Such symptoms and hallmarks include, but are not limited to seizures, hypotonia, sensory integration disorders, motor development delays and dysfunctions, intellectual and cognitive dysfunctions, movement and balance dysfunctions, visual dysfunctions, delayed language and speech, gastrointestinal disorders, neurodevelopmental delays, sleep problems, and sudden unexpected death in epilepsy.
Patent AU-2021344762-A1 (AU)
Title: Method and apparatus for treatment of organic waste
Inventor: FUSARELLI PETER
IPC: C05F17/05
Filed: 2021-09-21
Abstract: A method for treating organic waste material, the method comprising the steps of: - treating a quantity of organic waste using an anerobic digestion process; and then - treating at least some of the product from the anaerobic digestion process using a vermiculture process, resulting in the output of solid and liquid fertilizer products.
Patent AU-2021372556-A1 (AU)
Title: Parameter based construction
Inventor: ELLEN MURRAY EDINGTON
IPC: G06Q50/08
Filed: 2021-10-29
Abstract: A computer implemented method (900) of constructing a building (124) comprising receiving (903) an input specification (104) specifying pre-harmonisation modules (129', 127', 141') required to construct the building, said modules defined by pre-harmonisation module specifications (103, 102, 101, 147) comprising respective geometric parameters (1001, 1102, 1201) and respective attributes (1002, 1102, 1202); identifying (905) which of the pre-harmonisation module specifications are stored in a database (110), said identified pre-harmonisation module specifications having associated geometric parameters and attributes which are stored in separate sections of the database; harmonising (300, 400, 500, 600) the module specifications in the first pre-harmonisation module specifications to form a set (120) of harmonised module specifications (129, 127, 141) which specify harmonised modules which (a) substantially do not clash when they are used to construct the building (124), and (b) when assembled to form the building (124) satisfy attribute criteria specified in the input specification (104); and constructing (911) the building (124) using the harmonised module specification (120).
Patent AU-2021390924-A1 (AU)
Title: A silencer for a blast nozzle
Inventor: ROWLAND MATTHEW DAVID CAMPBELL
IPC: B24C5/04
Filed: 2021-12-02
Abstract: A noise suppressed blasting system comprising: a source of blasting gas in a predetermined pressure range with abrasive particles entrained therein; a nozzle including a nozzle inlet for connection to the source of blasting gas, a nozzle outlet for emission of the blasting gas, a nozzle conduit from the nozzle inlet to the nozzle outlet including a throat therebetween with a ratio of area of the nozzle outlet to area of the throat selected to emit the blasting gas from the nozzle outlet to produce a supersonic jet; a silencer connectable to the nozzle, to receive the supersonic jet exiting the nozzle, the silencer comprising a body with a silencer conduit therethrough, the body being of sufficient length and diameter to cause a flow condition of the jet received from the nozzle outlet to be modified such that 1½ shock cells are created in a jet inside the silencer, no shock cells are created in the jet outside the silencer and a jet exits the silencer in the form of a core jet with an established turbulent shear layer thereabout and entraining an annular jet located around the core jet..
Patent AU-2021391551-A1 (AU)
Title: Pixelwise predictions for grasp generation
Inventor: Rudy Jan Stanislaw
IPC: B25J9/16
Filed: 2021-12-01
Abstract: Provided are an apparatus and method for grasp generation, involving obtaining image data, comprising depth data, representative of an image of an object captured by a camera, and providing the image data to a grasping model comprising a neural network trained to predict a plurality of outcomes associated with a grasping operation independently based on images of graspable objects. A plurality of pixelwise predictions corresponding to the plurality of outcomes are obtained, each pixelwise prediction being a representation of pixelwise probability values corresponding to a given outcome of the plurality of outcomes associated with the grasping operation. The plurality of pixelwise predictions are aggregated to obtain an aggregated pixelwise prediction which is output for selection therefrom of one or more pixels on which to base generation of one or more grasp poses to grasp the object.
Patent AU-2021399169-A1 (AU)
Title: Tyre tread for a heavy vehicle with improved robustness
Inventor: SPINNLER OLIVIER
IPC: B60C11/03
Filed: 2021-12-03
Abstract: The present invention relates to a tyre tread (1) for a heavy civil engineering vehicle, having an improved compromise between resistance to mechanical aggression by stony soils and grip on muddy soils. The tread (1) comprising five rows (41, 42, 43), separated two-by-two by a longitudinal cut-out (51, 52), and distributed, in the transverse direction (YY'), into a middle row (43), two intermediate rows (42) and two lateral rows (41), the blocks (31, 32, 33) of a single row (41, 42, 43) being at least partly separated two-by-two by a transverse cut-out (61, 62, 63), each transverse cut-out of a lateral row (41) is a transverse groove, each transverse cut-out (62) of an intermediate row (42) is either a blind transverse groove (621) or a transverse incision (622), arranged alternately in the longitudinal direction XX', and each internal longitudinal cut-out (52) separating two adjacent intermediate and median rows (42, 43), respectively, is a longitudinal groove.
Patent AU-2021400316-A1 (AU)
Title: Oral care compositions with amine flourides
Inventor: HUBER NORBERT
IPC: A61Q11/00
Filed: 2021-12-17
Abstract: The present disclosure relates to storage-stable compositions comprising amines and zinc-containing compounds. Related methods of use and making are further disclosed
Patent AU-2021431521-A1 (AU)
Title: Delivery device apparatuses, systems, and methods
Inventor: ZEIRA EITAN
IPC: A61M37/00
Filed: 2021-12-31
Abstract: A delivery device may comprise a main body including a central region and a peripheral region. The central region may be shaped substantially as a thimble and may have a top surface and a base. The peripheral region may be defined by a plurality of petal members. The plurality of petal members may extend outward from the base. The delivery device may further comprise an adhesive coupled to at least a part of the main body. The delivery device may further comprise a collapsible reservoir coupled to the main body and to at least one delivery sharp.
Patent AU-2022202800-A1 (AU)
Title: Combinations and uses thereof
Inventor: ENDELL JAN
IPC: A61K39/395
Filed: 2022-04-28
Abstract: The present disclosure describes a pharmaceutical combination of an anti-CD19 antibody and a 
phosphoinositide 3-kinase inhibitor for the treatment of non-Hodgkin's lymphoma, chronic 
lymphocytic leukemia and/or acute lymphoblastic leukemia.
Patent AU-2022204640-A1 (AU)
Title: Additive dosing assemblies and hydro excavation vacuum apparatus incorporating same
Inventor: KEELEY JACOB
IPC: F04B15/02
Filed: 2022-06-29
Abstract: Hydro excavation apparatus for excavating earthen 
material are disclosed. The hydro excavation apparatus 
includes a first reservoir for holding a base fluid 
therein, a second reservoir for holding an additive 
therein, a vacuum system for removing earthen material 
from an excavation site, and an additive dosing assembly.  
The additive dosing assembly includes at least one of a 
pump and a valve fluidly connected to the second 
reservoir. The additive dosing assembly is selectively 
controllable to introduce an additive into at least one 
of the base fluid and the removed earthen material.
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CC
Patent AU-2022208208-A1 (AU)
Title: Multi-layer oral thin film
Inventor: LINN MICHAEL
IPC: A61K9/00
Filed: 2022-01-14
Abstract: The present invention relates to a multi-layer oral thin film, comprising a first and a second matrix layer, each containing at least one polymer; and a separation layer present between the first and the second matrix layer, the separation layer comprising at least one polyethylene glycol. The invention also relates to a method for producing the thin film and to its use as a drug.
Patent AU-2022212854-A1 (AU)
Title: Toxin molecule suitable for antibody-drug conjugate
Inventor: LI AO
IPC: C07D491/22
Filed: 2022-01-28
Abstract: The present invention provides a toxin molecule suitable for an antibody-drug conjugate. In particular, the present invention provides a compound represented by formula (I) below or a pharmaceutically acceptable salt or hydrate thereof. The compound of the present invention can be used in the preparation of a pharmaceutical composition for treating diseases associated with tumor cell proliferation.