baber/WOPTO huggingface dataset:
Patent EP-1390064-A2 (EP)
Inventor: BANCHEREAU JACQUES F
IPC: C12N5/0789
Filed: 2002-03-11
Abstract: L'invention concerne une méthode de traitement de malignités par l'induction de réponses immunitaires. Selon un aspect de l'invention, la méthode de traitement d'une malignité consiste à administrer une quantité efficace d'un vaccin contenant des cellules présentant l'antigène chargées d'au moins deux agents choisis dans le groupe constitué par des antigènes de tumeur et des peptides dérivés d'antigènes de tumeur. Dans un autre mode de réalisation, ce vaccin contient au moins deux agents choisis dans le groupe constitué par des antigènes de tumeur et des peptides dérivés d'antigènes de tumeur qui ciblent des cellules présentant l'antigène chez le patient. Ces vaccins peuvent également contenir des cellules présentant l'antigène chargées d'antigènes de contrôle utilisés pour déterminer la compétence immunitaire du patient. L'évaluation des réponses immunitaires induites par le vaccin dans le sang fournit un facteur de prévision de l'efficacité du traitement.
Patent EP-1411987-A2 (EP)
Inventor: GRIFFITHS GARY L
IPC: A61K47/48
Filed: 2002-07-31
Abstract: The present invention relates to a method for targeting an agent towards a target site in a tissue comprising (a) administering to a tissue a multi-specific antibody (msAb) or multi-specific antibody fragment, comprising a targeting arm that binds to an antigen on the target site, and a capture arm that binds to a polymer conjugate; and (b) administering to the tissue a polymer conjugate that binds to the capture arm, with the polymer conjugate comprising a polymer conjugated to an agent selected from the group consisting of a therapeutic agent, a peptide, an enzyme and a labeled ligand. The present invention also relates to a kit, useful for targeting a target site in a tissue or tissue sample, comprising, (a) a multi-specific antibody or antibody fragment comprising a targeting arm that binds to an antigen on said target site, and a capture arm that binds to a polymer conjugate or hapten- polymer conjugate; and (b) a polymer conjugate that binds to the capture arm, with the polymer conjugate comprising a polymer conjugated to an agent selected from the group consisting of a therapeutic agent, a peptide, an enzyme and a labeled ligand.
Patent EP-1412022-A2 (EP)
Inventor: SCHAUERTE PATRICK
IPC: A61N1/36
Filed: 2002-07-29
Abstract: The invention relates to a device for temporary reduction of heart movement during an operation, more particularly a heart operation, comprising a neurostimulation unit (20) for stimulation of the nerves (3) that slow down heart frequency, said unit including at least one electrode device (1) with at least one stimulation pole (2), wherein a control unit (19) connected to the neurostimulation device (20) is provided. Said control device has a first input device (26) for inputting a degree of immobilization and is configured to influence the operating state of the neurostimulation device (20) depending on the previously set degree of immobilization.
Patent EP-1451346-A2 (EP)
Inventor: HJALT TORD
IPC: C12Q1/6865
Filed: 2002-08-16
Abstract: Nouveau procédé de marquage d'ARNc utile pour sonder des microréseaux d'oligodésoxyribonucléotides. On soumet le modèle de polynucléotide voulu à une transcription inverse pour obtenir de l'ADNc bicaténaire en utilisant des amorces aléatoires incluant un promoteur d'ARN polymérase. Cet ADNc sert ensuite de modèle pour la synthèse d'ARN marqué par transcription in vitro en présence de précurseurs marqués.
Patent EP-1572890-A2 (EP)
Inventor: FRIEDMAN LORI
IPC: G01N33/574
Filed: 2002-06-05
Abstract: L'invention concerne des gènes humains SLC7 identifiés comme étant des modulateurs de la voie p53 et, de ce fait, constituant des cibles thérapeutiques pour des troubles associés à une fonction défectueuse de p53. La présente invention concerne également des procédés permettant d'identifier des modulateurs de p53, lesquels procédés consistent à cribler des agents modulant l'activité des SLC7.
Patent EP-1440019-A2 (EP)
Title: Packaging container for moist cloths or moist cosmetic pads
Inventor: MANGOLD RAINER
IPC: A47K10/42
Filed: 2002-10-17
Abstract: A packaging container for accommodating at least two stacks of moist cloths or moist cosmetic pads. The moist cloths or moist cosmetic pads of different stacks overlap only in one partial area in such a manner that a moist cloth or cosmetic pad of one stack protrudes into the partial area while being situated between two moist cloths or cosmetic pads of the other stack. The packaging container has an external shape that corresponds to the external shape of the moist cloths or moist cosmetic pads located in overlapping areas while, however, deviating from the respective fundamental shape of the moist cloths or cosmetic pads. A removal opening is provided in a manual access area located on the overlapping area of the moist cloths or cosmetic pads.
Patent EP-1446507-A2 (EP)
Inventor: BRISSETTE WILLIAM H
IPC: C12Q1/68
Filed: 2002-10-31
Abstract: The present invention provides novel panels of molecular targets that regulate erythropoiesis. The novel panels of the invention may be used, for example, in therapeutic intervention, therapeutic agent screening, and in diagnostic methods for diseases and/or disorders of erythropoiesis.
Patent EP-1456229-A2 (EP)
Inventor: BOFFELLI PHILIPPE
IPC: C07K7/56
Filed: 2002-12-12
Abstract: L'invention a pour objet un procédé de préparation des composés de formule (I) : R étant tel que défini dans la description ainsi que leurs sels, les intermédiaires, l'application du dichlorhydrate comme médicament et les compositions pharmaceutiques le renfermant.
Patent EP-1340491-A2 (EP)
Inventor: KROEPKE RAINER
IPC: A61K8/06
Filed: 2003-02-05
Abstract: A cosmetic and/or dermatological water-in-oil (W/O) emulsion breaking on the skin comprises by wt.  (A) an aqueous phase (minimum 75%); (B) a lipophilic phase (maximum 20%); (C) a hydrocolloid (0.1-5%) comprising a gum, polysaccharide, cellulose derivative, layered silicate, polyacrylate or other polymer; and (D) W/O emulsifier(s) (1-8%), the ratio (C) : (D) being 0.25-1 : 1.  A cosmetic and/or dermatological water-in-oil (W/O) emulsion breaking on the skin comprises by wt. (A) an aqueous phase (minimum 75%); (B) a lipophilic phase (maximum 20%); (C) a hydrocolloid (0.1-5%) comprising a gum, polysaccharide, cellulose derivative, layered silicate, polyacrylate or other polymer; and (D) W/O emulsifier(s) (1-8%) which is/are a surface-active compound of formula A-B-A/ where A and A/ = hydrophobic organic residues and B = hydrophilic group, the ratio (C) : (D) being 0.25-1 : 1.
Patent EP-1375917-A2 (EP)
Inventor: JACQUOT LAURENT MAXIMA ROLAND
IPC: F04D15/00
Filed: 2003-03-12
Abstract: Electric pump for the impulsion of liquids
comprises a suction chamber (5), a diffusion chamber and a pressure
chamber (6) through which the impelled liquid exits. The portion of the pump body (2)
that delimits said pressure chamber (6) is provided with at least two external suction
inlets (9;9'), adapted for receiving the liquid to be impelled, and a selection device (10)
which, acting as if it were a valve, selectively permits the inflow of the liquid by
one of the inlet channels, by several channels at the same time, or by none,
adapting itself to the different needs of the installation.
Patent EP-1353397-A2 (EP)
Inventor: HORIUCHI MICHIO
IPC: H01M8/02
Filed: 2003-03-29
Abstract: A fuel cell comprising a container (20) and a fuel cell
element or elements (16) contained in the container (20), to which
a mixed fuel gas containing a fuel gas and oxygen is fed
to generate electricity, and the gas having passed
through the fuel cell element or elements (16) is discharged,
as an exhaust gas, from the container (20), wherein the space (22,24)
other than the fuel cell element or elements (16) in the
container (20), through which the mixed fuel gas or the
exhaust gas flows, is filled with packing materials to
form a packed layer (26a,26b) having a gap between the adjacent
packing materials, at which gap the mixed fuel gas cannot
be ignited, during the operation of the fuel cell, even
if the mixed fuel gas has a fuel gas concentration within
the ignition limits for the mixed fuel gas, and a burn-up
section (18), in which the exhaust gas discharged from the
packed layer is burned, is provided at, or in the
vicinity of, the exhaust gas outlet of the container.
Patent EP-1413812-A2 (EP)
Inventor: SCHULZ DIETER
IPC: F16K41/12
Filed: 2003-06-25
Abstract: The membrane is accommodated in the valve housing (22) and serves as a seal between the housing (22) and the moving shaft (13). It is supported by two elements (20, 21) following fan-like every motion of the membrane on the side pointing towards the shaft (13) while supporting it. A first element is supported as the fan disk (20) against the lid of the valve housing (22) the second element (21) is attached to the movable shaft (13) as a fan shaft.
Patent EP-1387311-A2 (EP)
Inventor: HAYASAKI KIMIYUKI
IPC: G06K15/10
Filed: 2003-07-31
Abstract: In a printing apparatus which performs printing
by using a printhead having a printing element unit for
performing printing and a memory , the control circuit
of the printing apparatus main body outputs a command
for acquiring specific information from information
held by the memory block. Upon reception of this
command, the command control unit of a carriage control
unit generates an access signal containing an address
for reading out information designated by the command
from the memory block. The command control unit
accesses the memory block by the access signal, and
acquires specific information corresponding to the
command from the memory block.
Patent EP-1394670-A2 (EP)
Inventor: SUZUKI AKIHIRO
IPC: G06F3/12
Filed: 1995-10-20
Abstract: A Job processing device for sequentially storing jobs in a queue and for which
processing requests were received from terminals, said job processing device
comprising: a plurality of queues provided corresponding to states of the jobs;
scheduling means for scheduling the jobs using the plurality of queues; and queue
control means which moves the job being held in the queue, when the state of the job
has changed, to another queue provided corresponding to the state of the job, job
execution means for sequentially executing the jobs being held in the plurality of
queues.
Patent EP-1484668-A2 (EP)
Inventor: MATSUI YUKO
IPC: G06F12/16
Filed: 2003-09-04
Abstract: A method controls a storage system including
a first storage apparatus (200) including a first
storage volume (230) to store data therein, a second
storage apparatus (200) including a second storage
volume (230) to store data therein, the first and
second storage apparatuses being communicably
connected, and an information processor (100)
communicably connected to the first storage apparatus.
The method includes the steps of transmitting by the
information processor an identifier (LU 11, LU 12, LU
13) to identify the second storage volume in the second
storage apparatus to the first storage apparatus
(S1000), describing by the first storage apparatus the
identifier in a data input/output request for the
second storage volume and transmitting the data
input/output request to the second storage apparatus
(S1009), and executing by the second storage apparatus
data input/output processing for the second storage
volume identified by the identifier described in the
data input/output request (S1010).
Patent EP-1416248-A2 (EP)
Inventor: SKERKA WOLFGANG
IPC: G01C19/38
Filed: 2003-09-16
Abstract: The compass has a transformer (14,16) with a winding on the primary element which is connected via an H bridge circuit (12) to a controllable input voltage source (10). The transformer also has at least one secondary winding on the other transformer core. The secondary winding has several tap points for voltage supply for the heating, for the circuitry which controls the internal voltage supply, for the compass ball motor supply etc.
Patent EP-1452624-A2 (EP)
Inventor: BOK LOWELL D
IPC: C23C16/455
Filed: 2003-10-23
Abstract: A CVI furnace is described in which single layer of a porous material or
multiple layers of porous materials stacked in a module are loaded into a furnace.
The modules are loaded into the furnace singularly or as multiple units stacked
vertically or side by side. The modules can be moved through the furnace
continuously or step-wise. The furnace comprises a separate CVI chamber. The
porous material is heated and subjected to densification, thereby ensuring a
dispersion of the reactant gas onto the porous material. A process of densifying a
sheet of porous material is also described.
Patent EP-1437581-A2 (EP)
Inventor: DUELLINGS PETER
IPC: G06F11/34
Filed: 2003-12-02
Abstract: A computer (10) is connected (22) to an external device (20). It gives protection against tampering using statistical information and has a set of stored programs (12-14). An internal known program memory (30) for the first program is connected to a counter (32) and an equalizing field (34) is connected to a further circuit (36). The computer system includes a further counter (40) and an interface module (24).
Patent EP-1403848-A2 (EP)
Inventor: HIRATSUKA SATOSHI
IPC: G06F13/00
Filed: 2003-09-08
Abstract: Content delivering server has first content materials of a first format and second content materials stored in its memory. If a requesting client terminal to which content is to be delivered is of a type capable of using the first content material of the first format, the server creates single composite content including the first and second content materials. If the requesting client terminal to which content is to be delivered is of a type incapable of using the first content material of the first format, the server converts the first content material of the first format into a first content material of a second format capable of being used by the client terminal to thereby create single composite content including the converted first content material of the second format and the second content material, and then it delivers the thus-created content to the client terminal.
Patent EP-1388889-A2 (EP)
Inventor: CHEW HOE ANG
IPC: H01L21/8234
Filed: 2003-08-04
Abstract: A method of forming a dielectric layer on a semiconductor substrate,
comprised with multiple dielectric constants and multiple equivalent oxide
thicknesses (EOT), has been developed. After formation of a high dielectric constant
(high k), layer, on a semiconductor substrate, a first region of the high k layer is
subjected to a process directed at incorporating elements into a top portion of the
high k layer, while a second region of the high k layer remains protected during this
procedure. An anneal treatment results in the processed high k layer now exhibiting
a different dielectric constant, as well as a different EOT, than the unprocessed,
second region of the high k layer, not exposed to the above procedures.
Patent EP-1490370-A2 (EP)
Inventor: BOIE CHRISTIANE
IPC: C07D249/14
Filed: 2003-03-10
Abstract: L'invention concerne de nouvelles triazolopyrimidines de formule (I), dans laquelle R<1> représente un groupe amino ou un groupe alkyle, alcényle, alcinyle, cycloalkyle, alcoxy, alcényloxy, alcinyloxy, cycloalkyloxy, alkylamino, dialkylamino, alcénylamino, alcinylamino, cycloalkylamino, N-cycloalkyl-N-alkylamino, alkylidène-amino ou hétérocyclyle éventuellement substitué, R<2> représente un atome d'hydrogène ou un groupe alkyle, alcényle, alcinyle ou cycloalkyle éventuellement substitué, ou R<1> et R<2> forment avec l'atome d'azote auquel ils sont reliés un hétérocycle éventuellement substitué, R<3> représente un groupe aryle éventuellement substitué une fois à quatre fois, R<4> représente un atome d'halogène, un groupe cyano ou un groupe alcoxy ou dialkylamino éventuellement substitué et X représente un atome d'halogène. L'invention concerne en outre un procédé de production de ces nouvelles substances, ainsi que leur utilisation pour lutter contre des micro-organismes parasites. L'invention concerne par ailleurs de nouveaux produits intermédiaires de formules (II), (IV) et (VIa), ainsi que des procédés de production de ces produits.
Patent EP-1494989-A2 (EP)
Inventor: FILZEN GARY FREDERICK
IPC: C07D261/08
Filed: 2003-03-24
Abstract: This invention discloses compounds that alter PPAR activity. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agents for treating or preventing hyperlipidemia, hypercholesteremia, obesity, eating disorders, hyperglycemia, atherosclerosis, hypertriglyceridemia, hyperinsulinemia and diabetes in a mammal as well as methods of suppressing appetite and modulating leptin levels in a mammal. The present invention also discloses methods for making the disclosed compounds.
Patent EP-1585817-A2 (EP)
Inventor: ELMALEH DAVID R
IPC: A61K38/46
Filed: 2003-02-19
Abstract: The present invention provides biologically active agents covalently linked to a polymer. The polymer is preferably a biodegradable polymer. The biologically active agent is preferably a protein, such as an extracellular soluble protein, e.g., an extracellular enzyme. The enzyme can be an apyrase, e.g., NTP-Dase. Conjugates of the invention can be used as therapeutics in subjects. For example, a conjugate comprising an apyrase can be used for treating and preventing thrombosis, atherosclerotic plaque complications and vascular disorders.
Patent EP-1504395-A2 (EP)
Inventor: DEPAW THOMAS
IPC: G06Q40/04
Filed: 2003-05-14
Abstract: L'invention concerne un système informatisé (200), un procédé (300, 400, 500) et un progiciel (600, 700, 800) utilisés dans une transaction financière. Une cote et un ensemble de conditions sont établis. La cote comprend au moins un élément inclus dans la transaction. L'ensemble de conditions comprend une somme à financer. Un ensemble de documents financiers pour la transaction est produit en fonction de la cote et de l'ensemble de conditions de la transaction.
Patent EP-1499293-A2 (EP)
Inventor: ALBERTS DAVID S
IPC: A61K31/573
Filed: 2003-01-07
Abstract: On procède au mélange de l'alpha-DFMO topique avec un excipient hydrophile, et au moins un médicament actif supplémentaire en vue du traitement de kératoses actiniques par application topique du mélange sur les tissus cutanés humains. Selon une variante, on combine la triamcinolone stéroïde topique avec l'alpha-DFMO. Selon une deuxième variante, on combine le diclofénac anti-inflammatoire non stéroïde topique avec l'alpha-DFMO. Selon une troisième variante, on combine à la fois la triamcinolone et le diclofénac avec l'alpha-DFMO. Dans toutes les variantes, l'application topique de ces combinaisons s'est avérée inhiber le carcinome malpighien. L'effet combiné de ces composants, après sélection selon des proportions adéquates, inhibe les cellules du carcinome malpighien de manière bien plus sensible que l'utilisation séparée de chaque composant.
Patent EP-1497370-A2 (EP)
Inventor: BASTIOLI CATIA
IPC: B32B27/36
Filed: 2003-04-17
Abstract: A composition of one or more biodegradable aliphatic and/or aliphatic-aromatic thermoplastic polyester obtained by reactive extrusion of the polyesters with organic peroxides.
Patent EP-1578358-A2 (EP)
Title: Pituitary adenylate cyclase activating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use
Inventor: FROLAND WAYNE A
IPC: C07K14/705
Filed: 2003-07-11
Abstract: This invention provides novel peptides that function in vivo as agonists of the VPAC2 receptor. These insulin secretagogue polypeptides are shown to lower blood glucose in vivo more than controls upon glucose challenge. The polypeptides of this invention are also stable in formulation and have long half-lives. The peptides of the present invention provide a new therapy for patients with decreased endogenous insulin secretion, in particular type 2 diabetics. In particular, the invention is a polypeptide selected from a specific group of VPAC2-related polypeptides, or functional equivalents thereof. The invention is also directed to a method of treating a metabolic disease in a mammal comprising administering a therapeutically effective amount of the insulin secretagogue peptides to said mammal. Also disclosed are methods of making the peptides, both recombinant and synthetic.
Patent EP-1529003-A2 (EP)
Inventor: VIALET SERGE MARC ROGER
IPC: B65B9/14
Filed: 2003-07-21
Abstract: The invention concerns a packaging machine comprising a device for feeding a flexible tubular film, including a longitudinal guide (8) adapted to be longitudinally and completely engaged inside the tubular film (4), retaining means (11-14) adapted to bear said longitudinal guide and to allow through or to be traversed by the tubular film, and longitudinal driving means adapted to cause the tubular film to slide longitudinally when the latter is slipped onto the longitudinal guide, and longitudinal means (7) for receiving objects (2) to be packaged.
Patent EP-1556318-A2 (EP)
Inventor: KELLY KEVIN P
IPC: C07C2/66
Filed: 2003-09-25
Abstract: Cette invention concerne un procédé de production d'éthylbenzène par l'éthylation de benzène dans la phase critique sur un catalyseur d'alkylation aromatique à tamis moléculaires comprenant une zéolithe bêta dopée au cérium. Une matière de base aromatique présentant une teneur en benzène d'au moins 90 % en poids est disposée dans une zone de réaction et en contact avec la zéolithe bêta dopée au cérium présentant un rapport molaire silice-alumine compris entre 50 et 150 et un rapport cérium-aluminium compris entre 0,5 et 1,5. Un certaine quantité d'éthylène est ajoutée à la zone de réaction d'alkylation de façon qu'on obtienne un rapport molaire benzène-éthylène compris entre 1 et 15. La zone de réaction est activée dans des conditions de température et de pression permettant au benzène d'être dans la phase supercritique, entraînant l'éthylation du benzène en présence du catalyseur zéolithe bêta dopée au cérium. Un produit d'alkylation contenant de l'éthylbenzène comme produit primaire ainsi que des sous-produits alkylés plus lourds ne représentant pas plus de 60 % en poids de l'éthylbenzène sont ainsi produits. La réaction d'alkylation en phase critique peut être suivie de la transalkylation d'un composant aromatique polyalkylé.
Patent EP-1562418-A2 (EP)
Inventor: MARKELS MICHAEL JR
IPC: A01K61/00
Filed: 2003-11-07
Abstract: L'invention concerne un procédé pour accroître la prise de poisson dans l'océan, par utilisation d'engrais à la surface de l'océan. Ledit procédé consiste à créer une brève prolifération de phytoplancton pour former un dispositif attirant les poissons vers un emplacement planifié pour des bateaux de pêche, permettant ainsi la prise de poisson avec un effort de pêche réduit. La prolifération peut être créée par addition d'un engrais à base de fer chélaté à la surface de l'océan, pour une courte durée, comprise par exemple entre environ 1 et 2 mois.
Patent EP-1567971-A2 (EP)
Inventor: PORTER ROBERT MARK STEFAN
IPC: G06K9/00
Filed: 2003-11-28
Abstract: L'invention concerne un appareil de détection faciale qui génère un signal de sortie indiquant la vraisemblance de zones de test d'une image de test contenant un visage. Ledit appareil comprend des moyens permettant de comparer une zone de test avec des données de visage indiquant la présence d'un visage de façon à détecter plusieurs valeurs de vraisemblance respectives indiquant la vraisemblance de la zone de test contenant un visage d'un groupe de dimensions de visages différents correspondantes. Ledit appareil comprend également des moyens de commande qui répondent à des métadonnées associées à l'image définissant un des classements prédéterminés de l'image, pour modifier le groupe et/ou les valeurs de vraisemblance à l'égard une dimension de visage ou d'une fourchette de dimensions de visage appropriées pour le classement de ladite image.