baber/WOPTO huggingface dataset:
Patent AU-2020200175-B2 (AU)
Title: Site-specific conjugation of linker drugs to antibodies and resulting ADCS
Inventor: ARIAANS GERARDUS JOSEPH ANDREAS
IPC: A61K47/50
Filed: 2020-01-09
Granted: 2021-08-19
Abstract: The present invention relates to antibody-drug conjugates (ADCs) wherein a linker 
drug is site-specifically conjugated to an antibody through engineered cysteine, and their 
use as a medicament, notably for the treatment of human solid tumours and haematological 
malignancies, in particular breast cancer, gastric cancer, colorectal cancer, urothelial 
cancer, ovarian cancer, uterine cancer, lung cancer, mesothelioma, liver cancer, pancreatic 
cancer, prostate cancer, and leukaemia.
Patent AU-2020200777-B2 (AU)
Title: System and methods for positioning bone cut guide
Inventor: NIKOU CONSTANTINOS
IPC: A61B17/15
Filed: 2020-02-03
Granted: 2022-03-31
Abstract: Examples of an orthopedic surgical device for use in operating on a target bone and 
methods for operating a system for use in orthopedic surgery on a bone are generally 
described herein. An orthopedic surgical device can include an primary positioning block, 
and a secondary positioning component removably coupled to the primary positioning 
6 block. The secondary positioning component can be configured to: engage a prepared 
engagement feature machined into the target bone, and guide the primary positioning block 
to a predetermined position on a target bone. The orthopedic surgical device can include a 
first cutting block configured to: removably couple to the primary positioning block, and 
guide a cutting tool to cut the target bone.
WO 2015/131138 PCT/US2015/018161 
1/7 
1002 
FIG.I1A FIG.l1B 
206 206 W- 
200 
204 
9 208 
02 202 
FIG. 2
Patent AU-2020201643-B2 (AU)
Title: Oral anti-parasitic composition
Inventor: FEUGIER ALEXANDRE
IPC: A61K31/35
Filed: 2020-03-05
Granted: 2022-03-17
Abstract: Oral anti-parasitic composition 
5 The present invention relates to a composition for use as an oral anti-parasitic, the 
composition comprises one or more of an essential oil which contains gamma-terpinene, 
and/or carvacrol, and/or thymol, and/or terpinenol, and/or eucalyptol and/or eugenol, an 
essential oil of genus Cinnamomum, Eugenia, Eucalyptus or a source of saponin. It also 
relates to a method of preventing or treating parasitic infection in an animal, the method 
10 comprising orally administering to said animal a composition comprising one or more of an 
essential oil which contains gamma-terpinene, and/or carvacrol, and/or thymol, and/or 
terpinenol, and/or eucalyptol and/or eugenol, an essential oil of genus Cinnamomum, 
Eugenia, Eucalyptus or a source of saponin.
Patent AU-2020203859-B2 (AU)
Title: Tubes for medical systems
Inventor: STOKS ELMO BENSON
IPC: A61M16/08
Filed: 2020-06-11
Granted: 2021-09-16
Abstract: A medical tube for transporting gases to and/or from a patient. The medical tube has an elongate film spirally wrapped with 
an elongate reinforcing member, which bond to form a lumen. The elongate film has a profile such that the elongate film does not 
protrude into the lumen of the medical tube upon bending of the medical tube. The elongate reinforcing member can have a D
shaped cross section that can contribute to beneficial characteristics of the medical tube. The elongate reinforcing member can also 
have a circular cross section
Patent AU-2020203880-B2 (AU)
Title: Solid pharmaceutical compositions comprising biopterin derivatives and uses of such compositions
Inventor: SCHEURER PETER
IPC: A61P25/00
Filed: 2020-06-12
Granted: 2022-03-31
Abstract: The present invention relates to solid pharmaceutical compositions comprising biopterin 
derivatives as well as methods for obtaining such solid pharmaceutical compositions. The 
5 compositions contain the active ingredient and phosphate salts. They may be obtained by 
lyophilisation and reconstituted for intravenous administration. The invention also relates to the 
solid pharmaceutical compositions of the invention for treating diseases.
Patent AU-2020258783-B2 (AU)
Title: Road surface matting
Inventor: ANSON ANTONY
IPC: E01C9/08
Filed: 2020-04-14
Granted: 2021-11-18
Abstract: A problem with unpaved roads is that can be prone to damage when driven on. The invention provides surface matting for addressing this, comprising a first mat (1a) and a second mat 1b, each mat having a series of substantially parallel beams (2), a plurality of spine rods 3 that run substantially perpendicular to and through the beams and connect the beams to one another. Each mat also has a joiner (7) adjacent an edge of the mat, arranged so that one of the spine rods passes through the joiner. The matting is such that the first and second mats are connected to one another by way of a connecting rod 8 that passes through and connects the joiner (8) of one mat to the joiner of the other mat.
Patent AU-2020266339-B2 (AU)
Title: Dissolvable polymeric eye inserts and method of using same
Inventor: KETELSON HOWARD ALLEN
IPC: A61K9/00
Filed: 2020-05-01
Granted: 2023-12-07
Abstract: Polymeric eye inserts are provided that may be dissolvable when placed in the cul-de-sac of the eye. These inserts may contain one or more polymers as well as a softener/plasticizer so that, when inserted into the eye, they may absorb tears, and dissolve and slowly release lubricant into the tear film to lubricate and protect the ocular surface for an extended duration of time. Increased retention time on the ocular surface for longer lasting relief may reduce dosing frequency and patient burden typically associated with topical drop usage. These polymeric eye inserts also may include one or more pharmaceutically active agents.
Patent AU-2020351072-B2 (AU)
Title: Mobile device navigation system
Inventor: MAYOR ROBERT WILLIAM
IPC: G01C21/36
Filed: 2020-07-28
Granted: 2023-05-11
Abstract: Location mapping and navigation user interfaces may be generated and presented via mobile computing devices. A mobile device may detect its location and orientation using internal systems, and may capture image data using a device camera. The mobile device also may retrieve map information from a map server corresponding to the current location of the device. Using the image data captured at the device, the current location data, and the corresponding local map information, the mobile device may determine or update a current orientation reading for the device. Location errors and updated location data also may be determined for the device, and a map user interface may be generated and displayed on the mobile device using the updated device orientation and/or location data.
Patent AU-2021201040-B2 (AU)
Title: Fixation device for securing a linear element to a workpiece
Inventor: EAVES FELMONT F
IPC: A61B17/04
Filed: 2021-02-17
Granted: 2023-03-23
Abstract: FIXATION DEVICE FOR SECURING A LINEAR ELEMENT 
TO A WORKPIECE 
Abstract 
A fixation device (100) for securing a linear element 
(40) to a workpiece (70) is disclosed. The fixation device 
comprises: a contact component (101) configured to be engaged 
against a workpiece; an opening (103) for receiving a linear 
element; and a fixation component (104) for securing a portion 
of the linear element to the fixation device, wherein the 
fixation component is connected to, and extends away from, the 
contact component, and wherein the fixation device is 
configured to be bent so that an angle defined between the 
fixation component and the contact component is reduced to 
reduce the profile of the fixation device.
100 6/20 101 103 100 
101 
103 109 
FIG. 5A 1 
0104 
105 FiG 5 
101 107 
104 
----- -----100 
10, 111 
103 
FIGS5D 
100 
0 FIG. 50 
100 1101o 0 
FIGS E 
101 103 101 
10410 11 
104--,
108 --/109 
105 
FIG. 5F 107FI 6
Patent AU-2021201916-B2 (AU)
Title: Rhythmic Synchronization Of Cross Fading For Musical Audio Section Replacement For Multimedia Playback
Inventor: LYSKE JOSEPH MICHAEL WILLIAM
IPC: G10H1/40
Filed: 2021-03-26
Granted: 2021-07-29
Abstract: Music context system, audio track structure and method of real-time synchronization of musical 
content FIG. 2 represents a system (30) that permits identified musical phrases or themes to be 
synchronized and linked into changing real-world events (12). The achieved synchronization 
5 includes a seamless musical transition - achieved using a timing offset, such as relative 
advancement of a significant musical "onset", that is inserted to align with a pre-existing, 
aligned, identified beat, music signature or time base - between potentially disparate 
pre-identified audio sections (e.g. musical phrases) having different emotive themes defined by 
their respective time signatures, intensities, keys, musical rhythms and/or musical phrasing.  
o Synchronisation of cross-fading or cutting or splicing audio sections with beat for rhythmic 
coherence. The earliest onset is faded first. The system operates to augment an overall sensory 
experience of a user in the real world by dynamically changing, re-ordering or repeating and then 
playing audio themes within the context of what is occurring in the surrounding physical 
environment, e.g. during different phases of a cardio workout in a step class the music rate and 
5 intensity increase during sprint periods and decrease during recovery periods. Based on a 
pre-inserted key, the accompanying music is re-ordered from an original track and selected 
automatically - optionally in real-time - to accompany detected or identified changing physical 
events, such as a heart-rate sensed and reported during a cardio-workout session. The system 
therefore produces and supplies for use, such as immediate play or broadcast, a composite media 
o file (54) that correlates instantaneous or changing real-word events with customized and 
user-selectable audio components designed to augment an overall sensory experience.
-6/11
onsetA 
Active Play S 
132 
cut point 
180 onsetD 
Destination 
134 i 
cut point FIG. 6a 
time base (relative to fraction) 
150 
onsetA 
Active Play S3 
132 I 
180- cut point 180 onsetD 
Destination 
134 
cut point FIG. 6b 
time base (relative to fraction) 
150 
Active Play 
132 
cut point 
Destination 
134 
PI 
FIG. 6c 
time base (relative to fraction) 
150
000 
020 
U2~eq
Patent AU-2021212110-B2 (AU)
Title: Novel human serum albumin mutant
Inventor: TAKAHASHI KENICHI
IPC: A61P43/00
Filed: 2021-08-06
Granted: 2022-07-14
Abstract: Disclosed are a human serum albumin mutant that can be linked to a physiologically 
active protein to increase the stability of the protein in the blood, as well as a 
resulting protein produced by linking with the mutant. The protein produced by 
linking with the mutant consists of a human serum albumin mutant comprising the 
amino acid sequence set forth as SEQ ID NO:3 or an amino acid sequence that, in 
comparison with it, lacks not more than 10 amino acid residues and/or has not more 
than 10 amino acid residues replaced, with the proviso that the asparagine residue 
occurring at position 318 and the threonine at position 320 from the N-terminus of 
the amino acid sequence set forth as SEQ ID NO:3 are preserved and linked by 
peptide bonds via a single amino acid residue (X) except proline placed between those 
two amino acid residues, and a physiologically active protein linked to the mutant.
Patent AU-2021239894-B2 (AU)
Title: Illumination devices for inducing biological effects
Inventor: EMERSON DAVID T
IPC: A61N5/06
Filed: 2021-02-26
Granted: 2022-06-30
Abstract: Illumination devices for impinging light on tissue, for example within a body cavity of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, increasing endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores, and inducing an anti-inflammatory effect. Biological effects may include upregulating and downregulating inflammatory immune response molecules within a target tissue. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and tissues with increased efficacy and reduced cytotoxicity.
Patent JP-3800394-B2 (JP)
IPC: G01R1/00
Filed: 2000-06-07
Granted: 2006-07-26
Abstract: A method for quantitatively determining probe card errors relying on merging data sets from a probe card analysis machine and a scrub mark analysis machine. Minimizing error values related to the data sets provides an indication of probe card/ probe machine combination tolerance. <IMAGE>
Patent JP-3566650-B2 (JP)
IPC: B62M25/00
Filed: 2000-11-30
Granted: 2004-09-15
Abstract: An assisting apparatus (14) for using power from a rotating member to assist an operation of a bicycle transmission comprising: a mounting member (300); a cam member (304) for rotation around a cam axis, wherein the cam member (304) has a cam surface (308), and wherein the cam member (304) receives rotational power from the rotating member; a cam follower (311) having a cam engaging element (334) and a transmission actuating element coupling member (320), wherein the cam engaging element (334) cooperates with the cam surface (308) for moving the cam follower in response to rotation of the cam member (304), and wherein the transmission actuating element coupling member (323) communicates movement of the cam follower (311) to a transmission actuating element (320); and an operating member that causes the cam follower (311) to be moved by rotation of the cam member (304). <IMAGE>
Patent JP-4246376-B2 (JP)
IPC: C07C47/04
Filed: 1998-07-10
Granted: 2009-04-02
Abstract: A process for the removal of formaldehyde species from a liquid carboxylic acid or carboxylic acid ester stream which forms a two-phase mixture with water is disclosed which comprises the step of subjecting the liquid organic mixture to at least one liquid liquid extraction stage wherein water is used as an extractant to produce an organic phase stream which is substantially formaldehyde free and an aqueous phase stream which contains substantially all of the formaldehyde in the output streams from the liquid liquid extraction. The process is particularly useful for reducing the formaldehyde content of a methyl methacrylate product stream.
Patent JP-3867123-B2 (JP)
IPC: A61K47/00
Filed: 1998-11-18
Granted: 2007-01-10
Abstract: The invention relates to a pharmaceutical composition having the following constituents: azelaic acid, polyacrylic acid, triacylglyceride, propylene glycol, polysorbate, soya lecithin, water and salts. The composition is a hydrogel which is suited for the treatment of rosacea, presbyderma, melasma or skin irritations.
Patent JP-4975902-B2 (JP)
IPC: A23L19/00
Filed: 1999-04-23
Granted: 2012-07-11
Abstract: The invention provides a unit dosage form such as a tablet, lozenge, capsule, powder, granulate or gel, the unit dosage form containing an aqueous extract of tomato in a dried form, the aqueous extract having been prepared by homogenising the flesh of a tomato and removing solids therefrom. The unit dosage form contains a water soluble active fraction which is colourless or straw coloured and has platelet aggregation inhibitory activity. <IMAGE>
Patent JP-3662850-B2 (JP)
IPC: C12Q1/68
Filed: 1999-06-24
Granted: 2005-06-22
Abstract: The invention relates to compositions and methods for decoding microsphere array sensors based on beads which comprise nucleic acids and identifier probes for decoding the arroy.
Patent JP-3514730-B2 (JP)
IPC: B21D41/04
Filed: 1999-10-27
Granted: 2004-03-31
Abstract: The present invention, the objective of which is to enable a reduction of the number of component parts of a drawing system, improve the durability and accuracy of the final casting shape with a mandrel device, by utilizing a compact speed-change mechanism, is constructed by comprising, at the tip of the spindle 10, a drawing tool mounting base 15 for slidably supporting a drawing tool R in a radial direction and, at the tip of a cam shaft 24 inserted concentrically with the spindle 10, a cam plate 22 for moving the drawing tool R in a radial direction, the spindle 10 and cam shaft 24 being engaged with each other through a speed-change mechanism 30, disposing the speed-change mechanism in parallel with the spindle 10 and cam shaft 24, and comprising the spindle 10 and the cam shaft 24 with hollow shafts. <IMAGE>
Patent JP-4488626-B2 (JP)
IPC: A61K47/48
Filed: 1999-12-03
Granted: 2010-06-23
Abstract: The present invention relates to a mycobacterial deoxyribonucleic acid (B-DNA) preserved and complexed on the mycobacterial cell wall (BCC) and a pharmaceutically acceptable carrier, wherein the BCC is effective in treating an inflammation in an animal having an inflammation. More particularly, the present invention relates to a Mycobacterium phlei deoxyribonucleic acid (M-DNA) preserved and complexed on Mycobacterium phlei cell wall (MCC) and a pharmaceutically acceptable carrier, wherein the MCC is effective in treating an inflammation in an animal having an inflammation.
Patent JP-3623449-B2 (JP)
IPC: G10L19/00
Filed: 2000-04-12
Granted: 2005-02-23
Abstract: In a method for concealing an error in an encoded audio signal a set of spectral coefficients is subdivided into at least two sub-bands ( 14 ), whereupon the sub-bands are subjected to a re-verse transform ( 16 ). A specific prediction is performed ( 18 ) for each quasi time signal of a sub-band to obtain an estimated temporal representation for a sub-band of a set of spectral coefficients following the current set. A forward transform ( 20 ) of the time signal of each sub-band provides estimated spectral coefficients which can be used ( 28 ) instead of erroneous spectral coefficients of a following set of spectral coefficients, e.g. in order to conceal transmission errors. Transforming at the sub-band level provides independence from transform characteristics such as block length, window type and MDCT algorithm while at the same time preserving spectral processing for error concealment. Thus the spectral characteristics of audio signals can also be taken into account during error concealment.
Patent JP-4970676-B2 (JP)
IPC: B23B31/00
Filed: 2001-09-20
Granted: 2012-07-11
Abstract: The method involves circulating the lubricating fluid through a cavity (20), enclosing the chuck moving components (5,6) in sealed state, during the opening and closing movement of the power chuck. An Independent claim is also included for the power chuck.
Patent JP-4256088-B2 (JP)
IPC: H01L21/677
Filed: 2001-09-28
Granted: 2009-04-22
Abstract: PROBLEM TO BE SOLVED: To realize a semiconductor substrate accommodation apparatus which can effectively control growth of an oxide film on a metal film. SOLUTION: A drying agent 18 is provided within a cabinet 2 in order to maintain the relative humidity in the cabinet 2 to under 5%.
Patent JP-4883860-B2 (JP)
IPC: A61F2/44
Filed: 1999-08-27
Granted: 2012-02-22
Abstract: An intervertebral implant is shaped in the form of a hollow cylinder and has a cover face, a base face, a hollow cylinder wall with an outer lateral area and an inner lateral area, as well as a hollow cylinder central axis. The implant is formed at least 95 percent by volume of a radiolucent material which has a modulus of elasticity of between 1 and 20 GPa. Postsurgical observation is permitted by means of X-rays, and at the same time the implant has a high degree of biocompatibility.
Patent JP-4772243-B2 (JP)
IPC: A61K35/36
Filed: 2000-08-01
Granted: 2011-09-14
Abstract: Testosterone levels in men are increased by the oral administration of powdered maca and antler.
Patent JP-4677161-B2 (JP)
IPC: H04B1/707
Filed: 2000-12-08
Granted: 2011-04-27
Abstract: A method for operation of a receiver of a spread spectrum system. The method includes generating in the receiver an expected signal, the expected signal being a function of time and frequency correlating the received time and frequency of the received signal with time and frequency shifted parameters of the expected signal deriving a computational expression indicative of the value of the correlation at a point displaced in time by the time offset plus the time shift and displaced in frequency by the frequency offset plus the frequency shift, and comparing the correlation measure with the computational expression to determine the time offset and the frequency offset.
Patent JP-3682962-B2 (JP)
IPC: B65D43/26
Filed: 2002-05-27
Granted: 2005-08-17
Abstract: A cover (20) assembly includes a ring (10) mounted on a garbage bin (1), a cover (20) mounted on the ring (10) and a slot pivot device for slowly pivoting the cover (20) relative to the ring (10). The slow pivot device includes a slow pivot element (30) installed between the ring (10) and the cover (20). The slow pivot element (30) includes an internal tube (31), an external tube (32) enclosing the internal tube (31) and a spring (33) connected between the internal tube (31) and the external tube (32). Thus, rotation of the internal tube (31) relative to the external tube (32) exerts a torque on the spring (33). The spring (33) is received in the internal tube (31) so that an end thereof is connected with the internal tube (31). The internal tube (31) is received in the external tube (32) so that the other end of the spring (33) is connected with the external tube (32). The internal tube (31) includes a clip (312) formed on an internal side (31) thereof for clipping an end of the spring (31). The external tube (32) includes a clip (322) formed on an internal side thereof for clipping an opposite end of the spring (33). Damping oil is provided between the internal tube (31) and the external tube (32) so as to damp pivot of the internal tube (31) relative to the external tube (32). <IMAGE>
Patent JP-3782378-B2 (JP)
IPC: A47C7/14
Filed: 2002-08-12
Granted: 2006-06-07
Abstract: A human body support structure (26) for a chair (10) or recliner which provides a crossed series of cords (28, 32, 34, 36) mounted within an enclosed space formed by a rigid frame (20). Mounted on each of the cords are pins (30) with a longitudinal axis of each of the pins being oriented perpendicular to the cords. Located between directly adjacent pins is a spacer (48) with each spacer being mounted on a cord. The cords are slightly stretchable assuming a taut relationship when mounted relative to the frame. A human body is to be placed against and supported on the upper surface of the pins. <IMAGE>
Patent JP-4137593-B2 (JP)
IPC: B22D29/00
Filed: 2002-10-24
Granted: 2008-08-20
Abstract: Concepts for fabricating improved cores for investment casting are described. The cores are composite and include refractory metal elements (200,202,204,206,208,210,212,214,216) and ceramic elements (120). The refractory metal elements are provided to enhance the mechanical properties of the core and/or to permit the fabrication of cores having shapes and geometries that could not otherwise be achieved. In one embodiment, the entire core may be made of refractory metal components. The cores may be used to investment cast gas turbine superalloy components.
Patent JP-5139618-B2 (JP)
IPC: A61K39/39
Filed: 2001-06-20
Granted: 2013-02-06
Abstract: The present invention relates to compositions and fusion proteins containing at least two  Mycobacterium  sp. antigens, and nucleic acids encoding such compositions and fusion proteins. The compositions of the invention increase serological sensitivity of sera from individuals infected with tuberculosis, and methods for their use in the diagnosis, treatment, and prevention of tuberculosis infection.