baber/WOPTO huggingface dataset:
Patent WO-2020033866-A1 (WO)
Title: Methods and systems for assessing proliferative potential and resistance to immune checkpoint blockade
Inventor: MORRISON CARL
IPC: C12Q1/6886
Filed: 2019-08-09
Abstract: A method for characterizing tumor response to immune checkpoint blockade therapy, comprising: (i) obtaining tissue from the tumor; (ii) measuring, using the tissue, expression of one or more cell proliferation gene markers; (iii) determining, based on the measured expression of the one or more cell proliferation gene markers, a proliferation profile of the tumor; (iv) predicting, based on the determined proliferation profile, response of the tumor to immune checkpoint blockade therapy; and (v) determining, by a physician using the predicted response of the tumor to immune checkpoint blockade therapy, a therapy for the tumor.
Patent WO-2020041508-A1 (WO)
Title: Conformal damage-free encapsulation of chalcogenide materials
Inventor: SIMS JAMES SAMUEL
IPC: H01L21/67
Filed: 2019-08-21
Abstract: Methods and apparatuses for forming an encapsulation bilayer over a chalcogenide material on a semiconductor substrate are provided. Methods involve forming a bilayer including a barrier layer directly on chalcogenide material deposited using pulsed plasma plasma-enhanced chemical vapor deposition (PP-PECVD) and an encapsulation layer over the barrier layer deposited using plasma-enhanced atomic layer deposition (PEALD). In various embodiments, the barrier layer is formed using a halogen-free silicon precursor and the encapsulation layer deposited by PEALD is formed using a halogen-containing silicon precursor and a hydrogen-free nitrogen-containing reactant.
Patent WO-2020106346-A1 (WO)
Inventor: KEELING NICHOLAS ATHOL
IPC: H02J7/02
Filed: 2019-08-26
Abstract: In certain aspects, methods and systems for moving a magnetic field hot spot of a wireless power transfer device are disclosed. An example power transfer device generally includes at least one coil configured to generate a charging field, and a controller configured to vary, over time, a current applied to the at least one coil such that magnetic field values of the charging field at a plurality of different positions relative to the at least one coil are configured to change with time.
Patent WO-2020055720-A1 (WO)
Title: Apparatus and method for generating electricity with pressurized water and air flow media
Inventor: HECTOR FRANCIS
IPC: F15B1/26
Filed: 2019-09-09
Abstract: A facility for generating electricity, including a water source and a plurality of penstocks adapted for selective flow communication with the water source for delivering water from the water source to a turbine electricity generator. An electricity distribution system is provided having a first component adapted to deliver electricity generated by the turbine electricity generator to an electric grid and an alternative second component adapted to use the electricity to power an air compressor. A compressed air storage reservoir is provided for storing air compressed by the air compressor, including an outlet for selectively delivering the compressed air to the plurality of penstocks according to a predetermined sequence for providing energy to the water contained in the penstock to propel the water from the penstock to the turbine.
Patent WO-2020055768-A1 (WO)
Title: Methods for treating pancreatitis
Inventor: ENGLE DANNIELLE D
IPC: C07K16/30
Filed: 2019-09-09
Abstract: Provided herein is a method for preventing, treating, ameliorating, or managing pancreatitis in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an antibody or functional fragment thereof that binds to CA19-9.
Patent WO-2020072306-A1 (WO)
Title: Methods for reducing aggregation of bispecific antibodies
Inventor: JAGANNATHAN BHARADWAJ
IPC: A61K9/19
Filed: 2019-09-27
Abstract: The invention disclosed herein relates to methods for reducing aggregation of bispecific antibodies, for example reducing aggregation of bispecific T cell engager (BiTE) antibody constructs, resulting from storage under frozen conditions by holding the antibodies at certain temperatures after thaw.
Patent WO-2020081347-A1 (WO)
Title: Conversion of infrastructure model geometry to a tile format
Inventor: CONNELLY PAUL
IPC: G06T17/00
Filed: 2019-10-10
Abstract: In example embodiments, techniques are provided for converting geometry of an infrastructure model represented as high-level geometric primitives having a given symbology to low-level primitives, and encoding these low-level primitives into tile contents suited for transmission, and ultimately display upon, on a client device. An architectural split between frontend applications and backend applications may allow conversion of the high level primitives to be performed remote from the client devices by backend applications. Backend applications may be executed on robust hardware devices that execute software in a multi-threaded environment on powerful CPUs. By performing CPU-intensive operations on backend applications, frontend applications on client devices may be required to do little more than submit low-level primitives for rendering on their GPU.
Patent WO-2020086825-A1 (WO)
Inventor: YANCEY PETER
IPC: C23C4/02
Filed: 2019-10-24
Abstract: A method for cleaning a surface of a substrate with an atmospheric pressure plasma process in which a plasma is generated at atmospheric pressure. The plasma has an energetic species reactive with one or more components of an undesirable material on the substrate. In this method, the plasma flows from a nozzle exit as a plasma plume exiting into an ambient environment, and the surface of the substrate is exposed to the energetic species in the plasma plume, thereby producing an activated surface capable of adhering on contact a coating material to the activated surface.
Patent WO-2020101891-A1 (WO)
Title: Depth based dynamic vision sensor
Inventor: ZAHNERT MARTIN GEORG
IPC: G02B5/18
Filed: 2019-10-30
Abstract: An image sensor suitable for use in an augmented reality system to provide low latency image analysis with low power consumption. The image sensor may have multiple pixel cells, each of the pixel cells comprising a photodetector to generate an electric signal based on an intensity of light incident upon the photodetector. The pixel cells may include multiple subsets of pixel cells, each subset of pixel cells including at least one angle-of- arrival to-intensity converter to modulate incident light reaching one or more of the pixel cells in the subset based on an angle of arrival of the incident light. Each pixel cell within the plurality of pixel cells may include differential readout circuitry configured to output a readout signal only when an amplitude of a current electric signal from the photodetector is different from an amplitude of a previous electric signal from the photodetector.
Patent WO-2020101907-A1 (WO)
Title: Diesel exhaust fluid tank venting system
Inventor: NIMRICHTER JAN
IPC: F01N3/36
Filed: 2019-10-31
Abstract: An exhaust after-treatment system associated with a diesel engine includes a diesel exhaust fluid storage unit. The storage unit includes a diesel exhaust fluid tank and a vent system coupled to the tank and configured to regulate flow of air into the tank and fluid vapor out of the tank.
Patent WO-2020093016-A1 (WO)
Inventor: HE HONG
IPC: H04L1/18
Filed: 2019-11-01
Abstract: A device, system, method, machine readable medium. The method includes: decoding a physical downlink control channel (PDCCH) from a Node B, the PDCCH scheduling a physical downlink shared channel (PDSCH); determining at least one of a control resource set (CORESET) index or a starting control channel element (CCE) index of the PDCCH; decoding the PDSCH; determining, based the at least one of the CORESET index or the CCE index, a physical uplink control channel (PUCCH) resource to carry hybrid automatic repeat request ( HARQ) acknowledgment (ACK) (HARQ-ACK) feedback corresponding to the PDSCH to the Node B; and causing transmission of the HARQ-ACK feedback based on the PUCCH resource.
Patent WO-2020097398-A1 (WO)
Inventor: HAO MINGFENG
IPC: C07D277/66
Filed: 2019-11-07
Abstract: La présente invention concerne des composés de Formule (I), et des sels, solvates, hydrates, polymorphes, co-cristaux, tautomères, stéréo-isomères, dérivés isotopiquement marqués pharmaceutiquement acceptables, et leurs promédicaments. Les composés selon l'invention peuvent être des inhibiteurs de kinase ( par exemple , Janus kinase (JAK),  par exemple , Janus kinase (2) (JAK2)). L'invention concerne également des compositions pharmaceutiques et des kits comprenant les composés décrits. L'invention concerne en outre des procédés d'utilisation des composés fournis, des compositions pharmaceutiques, et des kits ( par exemple , pour traiter une maladie ( par exemple , maladie proliférative) chez un sujet en ayant besoin).
Patent WO-2020118124-A1 (WO)
Title: Transport apparatus for a person and method
Inventor: SPANTON JOHN MICHAEL
IPC: A61G7/10
Filed: 2019-12-05
Abstract: Disclosed is an apparatus and method for transporting a person from a position on the ground onto the apparatus generally in a horizontal orientation. The apparatus comprises a board assembly upon which the person is positioned lengthwise in a horizontal orientation. The board assembly includes a belt housing for at least one endless belt, and a battery powered drive system for rotating the belt. A hand-held, portable, external, detachable controller has a motor coupling that enables the battery powered drive system to be detachably connected to a battery within the controller. A coupling connector manually connected and disconnected to the drive system enables the coupling connector to engage and operate the drive system.
Patent WO-2020124034-A1 (WO)
Inventor: Gomez Alexander
IPC: C11C3/06
Filed: 2019-12-13
Abstract: L'invention concerne des compositions améliorées de carburant et des kits améliorés d'additif pour carburant qui servent à prolonger la stabilité dans diverses conditions ambiantes et à augmenter l'efficacité en carburant et l'économie de carburant tout en réduisant également de manière significative le niveau de multiples constituants d'émissions générés lors de la combustion des carburants comprenant du CO2, du NOx, du SOx, des matières particulaires PM2.5, PM10 et du noir de carbone. Les carburants peuvent comprendre les essences de carburants hydrocarbonés, les carburants diesel, les carburants biodiesel, les carburants diesel de biomasse, les carburants renouvelables, les carburants synthétiques, les carburants à base d'algues, les carburants kérosène ou les fiouls lourds ou peuvent en variante être des hydrosols, et comprendre un kit d'additif présentant un oléate de sorbitane, un alcool de polyoxyéthylène, un alkylèneglycol et une amine. Les carburants sont mélangés avec un additif et sont émulsifiés avec de l'eau douce, propre présentant une qualité d'eau de 1 micron ou moins.
Patent WO-2021133418-A1 (WO)
Title: Facilitation de la présentation de contenu interactif dans un environnement informatique en ligne
Inventor: BROWN DERRICK
IPC: G06F9/44
Filed: 2020-01-15
Abstract: Dans certains modes de réalisation, un système de placement de contenu sélectionne et attribue des objets de contenu pour une région d'affichage dans une interface d'utilisateur sur la base de priorités de contenu des objets de contenu et de priorités d'emplacement d'emplacements virtuels dans la région d'affichage. Le système de placement de contenu reçoit une demande d'objets de contenu à présenter dans la région d'affichage. Le système de placement de contenu détermine un agencement pour diviser la région d'affichage en multiples emplacements virtuels. Chacun des emplacements virtuels contient des points configurés chacun pour afficher un objet de contenu. Le système de placement de contenu détermine des objets de contenu et l'attribution des objets de contenu pour chacun des emplacements virtuels sur la base de priorités de contenu associées aux objets de contenu et de priorités d'emplacement des emplacements virtuels. Le système de placement de contenu transmet les objets de contenu conformément à l'attribution à une plateforme en ligne pour un affichage dans l'interface d'utilisateur.
Patent WO-2020150480-A1 (WO)
Inventor: HEYMACH JOHN
IPC: C12Q1/6886
Filed: 2020-01-16
Abstract: L'invention concerne des procédés et des compositions pour le traitement de cancers. Dans certains modes de réalisation, les cancers du NSCLC qui présentent une déplétion ou une mutation non fonctionnelle dans STK11 /LKB1 et/ou KEAP1/NRF2, éventuellement en combinaison avec une déplétion d'une mutation non fonctionnelle dans l'ATM, peuvent être particulièrement sensibles au traitement avec un inhibiteur d'ATM (ATMi) et/ou un inhibiteur d'ATR (ATRi) tel que, par exemple, l'AZD0156 ou l'AZD6738, éventuellement en combinaison avec un inhibiteur de PARP.
Patent WO-2020154228-A1 (WO)
Title: Signaling for round trip time (rtt) based positioning using stronger path tracking
Inventor: MANOLAKOS ALEXANDROS
IPC: H04W64/00
Filed: 2020-01-20
Abstract: The disclosed methods and apparatuses for round trip time (RTT) based positioning include generating or receiving a measurement report. The measurement report includes, for at least one transmission-reception point (TRP), a user equipment (UE) time difference and an offset of the at least one TRP. The UE time difference is a difference of a UE transmission time of an uplink reference signals (UL RS) to the at least one TRP and an earliest reception time representing a time of arrival (TOA) at the UE of an earliest path of a downlink reference signal (DL RS) from the at least one transmission-reception point (TRP). The offset is a difference of a stronger reception time representing a TOA at the UE of a stronger path of the DL RS from the at least one TRP and the earliest reception time.
Patent WO-2020154410-A1 (WO)
Title: Procédés de production de protéines multimères dans des cellules hôtes eucaryotes
Inventor: SIMMONS LAURA C
IPC: C07K16/00
Filed: 2020-01-22
Abstract: La présente invention concerne la production de polypeptides multimères ( par exemple , comprenant deux sous-unités ou plus, chaque sous-unité comprenant deux chaînes polypeptidiques ou plus, telles qu'un anticorps multispécifique ou bispécifique) dans des cellules hôtes eucaryotes. Selon certains modes de réalisation, la présente invention concerne des procédés de production d'un polypeptide multimère dans une cellule hôte eucaryote à l'aide d'une cellule hôte qui comprend un polynucléotide comprenant une séquence d'initiation de traduction liée de manière fonctionnelle à une trame de lecture ouverte codant pour chaque polypeptide du polypeptide multimère. De manière avantageuse, la présente invention démontre que l'accord de l'intensité des séquences d'initiation de traduction liées à chaque trame de lecture ouverte permet une production plus élevée du polypeptide multimère avec moins de produits secondaires assemblés de manière incorrecte. La présente invention concerne en outre des cellules, des procédés de criblage et des kits associés.
Patent WO-2020163203-A1 (WO)
Title: Frein magnétorhéologique à couple élevé et à réponse rapide
Inventor: Wellborn Patrick
IPC: F16F9/53
Filed: 2020-02-03
Abstract: La présente invention concerne un frein magnétorhéologique (MR). Le frein MR comprend un rotor construit au moins partiellement en un matériau ferromagnétique, et un boîtier qui supporte le rotor de telle sorte que le rotor et le boîtier peuvent tourner l'un par rapport à l'autre autour d'un axe, le boîtier et le rotor étant configurés de telle sorte qu'un espace de fluide soit défini entre le boîtier et le rotor, et des parties du boîtier adjacentes au rotor sont construites au moins partiellement d un matériau ferromagnétique. Un fluide MR est disposé dans l'espace de fluide. Une bobine de transport de courantest excitée pour générer un champ magnétique à l'intérieur des parties ferromagnétiques du rotor et du boîtier et agit sur le fluide MR. Au moins un élément constitué d'un matériau ayant une faible perméabilité magnétique est configuré pour acheminer les lignes de flux magnétique à travers un matériau de perméabilité supérieure avoisinant les côtés opposés de l'espace de fluide.
Patent WO-2020163766-A1 (WO)
Inventor: PARK DONGSU
IPC: C12N5/00
Filed: 2020-02-07
Abstract: Embodiments of the disclosure encompass methods and compositions for bone repair and bone injury healing. In some embodiments, the bone repair and bone injury healing utilizes the enhancement of migration of certain types of bone cells upon stimulation by a particular cytokine. In specific embodiments, migration of periosteal skeletal stem cells upon delivery of CCL5 and/or TNFα is enhanced and fosters bone repair and healing.
Patent WO-2020167624-A1 (WO)
Title: Pyrrolo[2,3-d]pyrimidine compounds for treating familial dysautonomia
Inventor: WANG JIASHI
IPC: A61P25/00
Filed: 2020-02-10
Abstract: The present description relates to compounds of formula (I) useful for improving pre-mRNA splicing in a cell. In particular, another aspect described herein relates to substituted pyrrolo[2,3-d]pyrimidine compounds, forms, and pharmaceutical compositions thereof and methods of use for treating or ameliorating familial dysautonomia.
Patent WO-2020168120-A1 (WO)
Inventor: WEI LILI
IPC: H04W36/30
Filed: 2020-02-13
Abstract: La présente invention concerne, selon certains modes de réalisation, des appareils et des procédés pour déterminer une périodicité de bloc de signal de synchronisation (SSB) pour une resélection de cellule. Dans certains modes de réalisation, un équipement utilisateur (UE) peut établir une première connexion avec un premier nœud d'accès et de liaison terrestre intégrés (IAB) en utilisant une première périodicité de SSB. L'UE peut effectuer un processus de resélection de cellule et déterminer si un certain nombre de nœuds d'IAB candidats comprennent ou non un nœud IAB candidat avec une périodicité de SSB candidate stockée précédemment qui correspond au nœud d'IAB candidat. Si l'UE identifie une périodicité de SSB candidate, l'UE peut établir une seconde connexion avec le nœud d'IAB candidat en utilisant la périodicité de SSB candidat. Si l'UE n'identifie pas une périodicité de SSB candidate stockée précédemment, l'UE peut établir une seconde connexion avec un second nœud d'IAB en utilisant une seconde périodicité de SSB qui est inférieure à la première périodicité de SSB.
Patent WO-2020181098-A1 (WO)
Inventor: FUCHS THOMAS J
IPC: G06T7/00
Filed: 2020-03-05
Abstract: Presented herein are systems and methods of clustering images using encoder-decoder models. A computing system may identify tiles derived from an image. Each tile may have a first dimension. The computing system may apply an image reconstruction model to the tiles. The image reconstruction model may include an encoder block having a first set of weights to generate embedding representations corresponding to the tiles. Each embedding representation may have a second dimension lower than the first dimension. The image reconstruction model may include a decoder block having a second set of weights to generate reconstructed tiles corresponding to the embedding representations. The computing system may apply a clustering model comprising a feature space to the embedding representations to classify each tile to one of a plurality of conditions.
Patent WO-2020185519-A1 (WO)
Title: Microfluidic device for hydrodynamic sorting and rheometry measurements of particles
Inventor: MOSSIGE ENDRE
IPC: C12M1/34
Filed: 2020-03-05
Abstract: Particle sorting/characterization is provided that has no solid obstacles and is therefore inherently clog-free. Instead of using obstacles/filters, one or more "virtual fluidic obstacles", which can be created by combinations of inlets and outlet flows (sources and sinks) are used to sort/characterize particles. Since particles and cells cannot cross the boundary of these virtual obstacles, they can be used for sorting. However, since there is no physical boundary (only a virtual or hydrodynamic one), the particles have no surface to adhere to and therefore clogging is avoided.
Patent WO-2020197842-A1 (WO)
Inventor: KARUPPAIAH CHOCKKALINGAM
IPC: H01M8/0668
Filed: 2020-03-17
Abstract: A fuel cell system includes a fuel cell stack, a fuel inlet conduit configured to provide a fuel to a fuel inlet of the fuel cell stack, an electrochemical pump separator containing an electrolyte, a cathode, and a carbon monoxide tolerant anode, a fuel exhaust conduit that operatively connects a fuel exhaust outlet of the fuel cell stack to an anode inlet of the electrochemical pump separator, and a product conduit which operatively connects a cathode outlet of the electrochemical pump separator to the fuel inlet conduit.
Patent WO-2020205270-A1 (WO)
Title: Pumping unit having zero-imbalanced beam, lagging counterweights, and setback crank point
Inventor: YAKIMCHUK DARIUS
IPC: F04B47/14
Filed: 2020-03-19
Abstract: A surface unit can operate as a longer stroke unit to reciprocate a rod string for a downhole pump in a well. The unit has an end weight that gives the walking beam and head a zero-imbalance about the unit's fulcrum point. The unit can also operate as a phased unit in which the counterweights of the crank arms lag behind the pivot connection and/or the crank point is disposed rearward of the equalizer bearing of the walking beam.
Patent WO-2020219247-A1 (WO)
Inventor: SARAF BINDIA
IPC: G06Q30/00
Filed: 2020-04-01
Abstract: Disclosed are systems, methods, and computer-readable media for a geographic recommendation platform. The geographic recommendation platform receives data identifying a geographic region specified by a user and gathers data relating to the geographic region. The geographic recommendation platform determines, based on the data relating to the geographic region, an anticipated demand for an item within geographic region. The anticipated demand indicates how likely the item is to be purchased by a user that is located within the geographic region. The geographic recommendation platform generates a recommendation for the item based on the anticipated demand. The recommendation indicates the anticipated demand for the item within the geographic region. The geographic recommendation platform transmits the recommendation to the user.
Patent WO-2021173166-A1 (WO)
Inventor: DAMAJ BASSAM
IPC: A61K36/12
Filed: 2020-04-07
Abstract: Disclosed herein include methods, compositions, and kits suitable for use in treating or reducing a symptom of a urinary condition, such as, for example, overactive bladder and urinary incontinence. The method can comprise administration of a composition comprising herbal extract preparations.
Patent WO-2021230882-A1 (WO)
Title: System amd method of wound assessment and treatment
Inventor: HENEGHAN DANIEL
IPC: A61B5/00
Filed: 2020-05-15
Abstract: The presently disclosed subject matter is generally directed to an improved system for assessing and treating a wound. Specifically, a wound is identified in a patient by uploading or entering information about the wound and/or patient (e.g., type of wound, wound location, patient history). The wound image is captured, such as through an imaging device (e.g., phone, tablet, computer) and uploaded to the system. The image is then reviewed by a professional, such as a medical professional that specializes in treating a variety of wounds. The disclosed system uses an algorithmic approach to develop a systematic method to integrate selected data about the patient and deliver clinical care suggestions immediately to the patient or caregiver.