baber/WOPTO huggingface dataset:
Patent CA-3143080-A1 (CA)
Inventor: BERNAD PABLO LUIS
IPC: F03D80/00
Filed: 2020-06-26
Abstract: La présente invention concerne des compositions de revêtement pour pales d'éolienne. Ces compositions sont particulièrement utiles en tant que couches de revêtement de surface pour pales d'éolienne et pour la protection des bords d'attaque. L'invention concerne également une pale d'éolienne revêtue d'une composition de revêtement selon l'invention et un procédé d'application de la composition de revêtement et un procédé de réparation et/ou de remplacement de la couche de revêtement existante sur une pale d'éolienne par application d'une composition de revêtement selon l'invention. L'invention concerne également un ensemble de composants comprenant la composition de base et l'agent de durcissement utilisés dans la composition de revêtement. La composition de revêtement utilisée pour le revêtement d'une pale d'éolienne comprend une composition de base contenant un ester polyétheraspartique de formule (I) ci-dessous, dans laquelle chaque R représente un résidu alkyle linéaire ou ramifié en C1-C10, tel qu'un résidu alkyle linéaire ou ramifié en C1-C6, tel que, par exemple, un résidu méthyle, éthyle, propyle ou butyle ; et dans laquelle X est un polyéther. La composition de revêtement comprend en outre un agent de durcissement.
Patent CA-3144809-A1 (CA)
Title: Clipping levels for non-linear adaptive loop filter
Inventor: STEPIN VICTOR ALEXEEVICH
IPC: H04N19/186
Filed: 2020-06-24
Abstract: A method for in-loop filtering by performing adaptive loop filtering on a reconstructed frame of a video stream, implemented by an encoding device or a decoding device, comprising forming differences between a pixel of the reconstructed frame and neighboring pixels in a connected area of the pixel, clipping the differences according to respective clipping levels, forming a weighted sum of the clipped differences, and adding the weighted sum to the pixel to determine a filtered pixel, wherein the respective clipping levels are chosen from a same set of clipping levels for the luma and chroma components.
Patent CA-3148630-A1 (CA)
Title: Fluid delivery systems, methods and apparatus to dispense fluid on an animal
Inventor: NICOLL JEFFREY D
IPC: A01K15/02
Filed: 2020-08-19
Abstract: Fluid delivery systems, methods and apparatus to dispense a dose of fluid on an animal, which may be particularly used for behavior modification of the animal, are disclosed. A system may particularly comprise an apparatus wearable by the animal. The apparatus is suitable for storing a fluid contained therein, and dispensing a dose of fluid on the animal, particularly to spur or otherwise induce behavior modification of the animal, particularly in response to training stimuli during a training scenario.
Patent CA-3149670-A1 (CA)
Inventor: MANIBUSAN ANTHONY
IPC: A61K41/00
Filed: 2020-08-06
Abstract: L'invention concerne des conjugués du colorant de phtalocyanine IR700 et d'un anticorps liant EGFR, tel qu'un anticorps cétuximab, et des compositions pharmaceutiques de ceux-ci. Selon certains aspects, les compositions contiennent un anticorps liant EGFR, tel qu'un anticorps cétuximab, qui est modifié par conjugaison au colorant IR700 à des positions spécifiques à l'intérieur de la chaîne lourde et/ou de la chaîne légère de l'anticorps cétuximab. Selon certains aspects, de tels conjugués sont capables de tuer des cellules ciblées suite à l'irradiation du conjugué. L'invention concerne également des procédés de fabrication associés et des procédés d'utilisation et des utilisations, y compris dans des traitements de tumeurs et des indications spécifiques anti-cancéreuses.
Patent CA-3150004-A1 (CA)
Inventor: KHARE VIVEK
IPC: A63F13/00
Filed: 2020-09-08
Abstract: L'invention concerne un procédé de production et de distribution de données d'animaux simulés, le procédé comprenant une étape de réception d'un ensemble de données d'animaux réels, obtenues, au moins partiellement, à partir d'un ou plusieurs capteurs destinés à recevoir, à stocker ou à envoyer des informations relatives à un ou plusieurs individus ciblés. Des données d'animaux simulés sont produites à partir d'au moins une partie des données d'animaux réels ou d'un ou plusieurs dérivés desdites données. Finalement, les données d'animaux simulés sont fournies à un dispositif informatique. Typiquement, un ou plusieurs paramètres ou variables du ou des individus ciblés peuvent être modifiés.
Patent CA-3152377-A1 (CA)
Title: Antimicrobial device using ultraviolet light
Inventor: JOHNSON SCOTT
IPC: H01J9/04
Filed: 2020-09-02
Abstract: An antimicrobial device, such as a flashlight, lantern, or lamp, is discussed herein. The antimicrobial device produces light in the ultraviolet (UV) spectrum (i.e., 150-250 nm), including 200-230 nm. The antimicrobial device includes an electron source, an extractor, and a target material. The electron source provides the electrons of sufficient energy to cause a photon to be released, whether by a target or by the electron itself. The extractor extracts the electrons from the electron source. The target material is a component at which the electron is directed. The target material can release a photon having a desired wavelength or within a desired wavelength range or cause the electron to release a photon having a desired wavelength or within a desired wavelength range.
Patent CA-3153421-A1 (CA)
Inventor: PEDEMONTE STEFANO
IPC: A61B6/00
Filed: 2020-10-02
Abstract: The present disclosure provides methods and systems directed to management and visualization of radiological data. A method for processing at least one medical image of a location of a body of a subject may comprise (a) retrieving, from a remote server via a network connection, the medical image; (b) identifying one or more regions of interest (ROIs) in the medical image, wherein the ROIs correspond to an anatomical structure of the location of the body of the subject; (c) annotating the ROIs with label information corresponding to the anatomical structure, thereby producing an annotated medical image; (d) generating educational information based at least in part on the annotated medical image; and (e) generating a visualization of the anatomical structure, based at least in part on the educational information.
Patent CA-3154387-A1 (CA)
Title: Anti-cd371 antibodies and uses thereof
Inventor: DANIYAN ANTHONY
IPC: C07K16/28
Filed: 2020-09-11
Abstract: The presently disclosed subject matter provides antibodies or antigen-binding fragments thereof that bind to CD371 and methods of using such antibodies or antigen-binding fragments thereof same. In certain embodiments, the anti-CD371 antibody or an antigen-binding fragment thereof comprises a heavy chain variable region comprising an amino acid sequence that is at least about 80%, at least about 85%, at least about 90%, at least about 95%, at least about 96%, at least about 97%, at least about 98%, at least about 99%, at least about 100% homologous or identical to the amino acid sequence set forth in SEQ ID NO: 1, SEQ ID NO: 3, SEQ ID NO: 5, SEQ ID NO: SEQ ID NO: 9, or SEQ ID NO: 11.
Patent CA-3156803-A1 (CA)
Title: Compositions et methodes comprenant des anticorps anti-nrp2
Inventor: BURMAN LUKE
IPC: A61K45/06
Filed: 2020-10-02
Abstract: L'invention concerne des anticorps humanisés et à maturation d'affinité et leurs fragments de liaison à l'antigène qui se lient spécifiquement à des polypeptides de neuropiline-2 (NRP2) humaine, y compris ceux qui modulent des interactions de liaison entre la NRP2 humaine et au moins un ligand de NRP2 et qui modulent ainsi des événements de signalisation en aval médiés par la NRP2 suivants, notamment des compositions thérapeutiques associées et des méthodes de modulation de l'activité de la NRP2 et de traitement de maladies telles que des maladies associées à la NRP2.
Patent CA-3158468-A1 (CA)
Title: Pharmaceutical composition for the treatment of pulmonary vascular disease and/or cardiac dysfunction in fontan-palliated patients
Inventor: CSONKA DENES
IPC: A61K31/5578
Filed: 2020-11-25
Abstract: The present invention relates to high doses of macitentan (INN), i.e. propylsulfamic acid [5-(4-bromo-phenyl)-6-[2-(5-bromo-pyrimidin-2-yloxy)-ethoxy]-pyrimidin-4-yl]-amide or pharmaceutically acceptable salts, solvates, hydrates or morphological forms thereof for use in the treatment of pulmonary vascular disease and/or cardiac dysfunction in functional single ventricular heart disease patients, especially in Fontan-palliated patients. Moreover, the present invention relates to the use of high doses of macitentan for the manufacture of a medicament as well as to a method for the treatment of said diseases. Further, the present invention relates to a dosage regimen as well as to a combination of macitentan with one or more phosphodiesterase type 5 (PDE5) inhibitors, prostacyclin analogues, prostacyclin receptor agonists or soluble guanylate cyclase stimulators. Besides, the present invention relates to a pharmaceutical composition for the treatment of pulmonary vascular disease and/or cardiac dysfunction in functional single ventricular heart disease patients, especially in Fontan-palliated patients comprising a high dose of macitentan. Moreover, the present invention relates to the use of high doses aprocitentan for the same purpose.
Patent CA-3159124-A1 (CA)
Title: Snubber apparatus for earth-working bucket
Inventor: GUILLEMETTE JESSY
IPC: E02F3/407
Filed: 2022-05-17
Abstract: An apparatus may have a casing defining an inner cavity delimited at least by a circumferential surface portion between a pair of lateral surface portions. A shaft passes through the inner cavity of the casing. A wiper arm rotates with the shaft, the wiper arm having a free end in close proximity to the surface portions of the inner cavity of the casing, the free end of the wiper arm having a contour complementarily corresponding to a profile of the circumferential surface portion of the inner cavity. A dam divides the inner cavity in chambers adapted to accommodate a fluid, with movements of the wiper arm changing the volume of the chambers, whereby the apparatus is configured to allow the fluid to flow between the chambers to oppose the force to the given motions. A cover plate(s) is connected to a lateral side of the casing and defining at least one outer chamber around the at least one end of the shaft and exteriorly of the inner cavity.
Patent CA-3160988-A1 (CA)
Inventor: GRAY NATHANAEL S
IPC: C07D253/00
Filed: 2020-11-11
Abstract: The disclosure relates to compounds that act as allosteric inhibitors of epidermal growth factor receptor (EGFR); pharmaceutical compositions comprising the compounds; and methods of treating or preventing kinase-mediated disorders, including cancer and other proliferation diseases.
Patent CA-3161502-A1 (CA)
Title: Isolated oleosome composition and process for preparing it
Inventor: CABAS-RODRIGUEZ LUCIA
IPC: A23D7/005
Filed: 2020-11-09
Abstract: The invention relates to a process for preparing an isolated oleosome composition with improved taste and the process is comprising the steps of subjecting an oleosome source to a roasting step and obtaining a roasted oleosome source, and subsequently isolating oleosomes from the roasted oleosome source, and obtaining the isolated oleosome composition. The invention also relates to an isolated oleosome composition obtainable by the process. The invention further relates to food and feed products, pharmaceutical products, personal care products, nutritional compositions and industrial products comprising the isolated oleosome composition. Finally, the invention relates to the use of a roasted oleosome source to improve taste and/or flavor of an isolated oleosome composition.
Patent CA-3162965-A1 (CA)
Title: Invasive temperature sensor system
Inventor: VAN DEN BOSSCHE JOHAN
IPC: A61B5/01
Filed: 2020-12-07
Abstract: A device (1) for measuring a temperature at one or more locations in an organ or tissue inside the human or animal body, a related kit and a related method are disclosed. The device comprises a catheter tube (2) having a distal end for inserting into the body and a proximal end for remaining outside the body in use of the device. The device comprises at least one resistive temperature sensor (3) in the tube, and a plurality of electrical wires (4) in the tube that are connected to the at least one resistive temperature sensor (3). The plurality of electrical wires comprise at least some electrical wires running from the proximal end of the tube through the tube (2). The device comprises a connector (21) at the proximal end of the tube (2) for electrically connecting the plurality of electrical wires (4) to an external device. The resistive temperature sensor (3) comprises a thermal resistor (11) and a first terminal (12) and a second terminal (13) between which a temperature dependent resistance of the thermal resistor can be measured, in which each of the two terminals (12,13) of the resistive temperature sensor (3) is directly connected to at least one of the plurality of electrical wires (4).
Patent CA-3163283-A1 (CA)
Inventor: SUBRAMANIAN ROMESH R
IPC: C07K16/28
Filed: 2021-01-08
Abstract: Des aspects de l'invention concernent des charges utiles moléculaires qui modulent l'expression ou l'activité de gènes impliqués dans la croissance et l'entretien musculaires (par exemple MSTN, INHBA, et/ou ACVR1B), et des complexes comprenant un agent de ciblage musculaire lié de manière covalente à de telles charges utiles moléculaires. Dans certains modes de réalisation, l'agent de ciblage musculaire se lie de manière spécifique à un récepteur de surface cellulaire d'internalisation sur une cellule musculaire (par exemple, une cellule du muscle cardiaque). Dans certains modes de réalisation, la charge utile moléculaire est un oligonucléotide, tel qu'un oligonucléotide antisens ou un oligonucléotide d'ARNi.
Patent CA-3171938-A1 (CA)
Title: A balanced insole structure with massage function
Inventor: Yin Jiqi
IPC: A43B13/18
Filed: 2022-09-13
Abstract: The invention discloses a balanced insole structure with a massage function and relates to the technical field of insoles. The balanced insole structure with a massage function includes an insole main body and a connecting portion; the arch portion of the insole main body is provided with a convex portion matched with the curvature of the sole of the foot; the connecting portion is connected to two ends on the lower side of the convex portion, thus forming a stabilization cavity through their connection; and the insole main body is also provided with a massage protrusion on its upper surface. In the invention, the provision of the insole main body with the massage protrusion on its upper surface can realize the massage function of the insole. In addition, the provision of the arch portion of the insole main body with the convex portion matched with the curvature of the sole of the foot, can well fit the curvature of the sole of the foot and improve the adaptability and comfort in use of the insole structure. Due to the connection of the connecting portion to the two ends on the lower side of the convex portion, the connecting portion will exert a pull effect on the two ends on the lower side of the convex portion, thereby preventing the deformation and failure of the insole resulting from the excessive expansion of the two ends on the lower side of the convex portion, which greatly improves the overall stability of the insole structure, prolongs the service life, and is convenient for widespread promotion.
Patent CA-3174447-A1 (CA)
Inventor: HATAYAMA TADATOMO
IPC: B23B51/08
Filed: 2021-03-04
Abstract: Selon la présente invention, dans une partie de support d'outil (40a) d'un outil d'usinage (10), une cartouche (48) est disposée de sorte à être mobile vers l'avant et vers l'arrière. Une came (50) logée à l'intérieur d'une partie de réception de came (40b) tourne pendant que la came (50) est en butée contre la cartouche (48) pour déplacer, de ce fait, la cartouche (48) vers l'avant et vers l'arrière. Une tige (54) qui se déplace vers l'avant et vers l'arrière à l'intérieur d'un corps d'outil (40) le long d'un axe (a), est pourvue d'une partie de butée (54a). La partie de butée (54a) vient en butée contre une position de butée (51) de la came (50) en fonction du mouvement vers l'avant et vers l'arrière de la tige pour faire tourner, de ce fait, la came (50). Un mécanisme de restriction (56) est capable de régler la phase de la came (50) lorsque la partie de butée (54a) est séparée de la position de butée (51) de telle sorte qu'une position de référence soit atteinte où la position de butée (51) fait face à la partie de butée (54a).
Patent CA-3174857-A1 (CA)
Title: Nut connection mechanism
Inventor: GOLDSTEIN EDWARD
IPC: F16B39/284
Filed: 2021-04-06
Abstract: Connection mechanisms utilizing nut restrainers and methods of use are presented, particularly as they apply to high-strength bolted connections for steel structures. Nut restrainers may include a base plate and a cap that accepts insertion of a nut, and may include deformable or removable protrusions that allow the nut and/or a cap to move laterally to accept a bolt that is inserted non-concentrically with the nut. A method of positioning a nut restrainer concentric with a bolt hole accurate to within the radial tolerance of the bolt hole is further disclosed.
Patent CA-3175485-A1 (CA)
Title: Methods and organisms for the growth-coupled production of 1,4-butanediol
Inventor: BURGARD ANTHONY P
IPC: G16B35/20
Filed: 2008-08-06
Abstract: The invention provides a non-naturally occurring microorganism comprising one or more gene disruptions, the one or more gene disruptions occurring in genes encoding an enzyme obligatory to coupling 1,4-butanediol production to growth of the microorganism when the gene disruption reduces an activity of the enzyme, whereby the one or more gene disruptions confers stable growth-coupled production of 1,4-butanediol onto the non-naturally occurring microorganism. The microorganism can further comprise a gene encoding an enzyme in a 1,4-butanediol (BDO) biosynthetic pathway. The invention additionally relates to methods of using microorganisms to produce BDO.
Patent CA-3176487-A1 (CA)
Title: Floor drain/cleanout protector
Inventor: NOONAN MICHAEL JOHN EDWARD
IPC: E03F5/04
Filed: 2022-09-22
Abstract: Certain embodiments provide a method of installing a floor drain/cleanout. The method generally includes positioning a drain/cleanout body comprising a first opening for receiving a finish drain/cleanout, disposing, on the drain/cleanout body, a cover base of a drain/cleanout cover assembly comprising a second opening for receiving the finish drain/cleanout, threading the finish drain/cleanout through the first opening and the second opening to retain the cover base on the drain/cleanout body, engaging an upper portion of the drain/cleanout cover assembly with the cover base of the drain/cleanout cover assembly, wherein engaging the upper portion with the cover base defines an enclosed void space above the finish drain/cleanout, installing a flooring material around at least the upper portion; removing the upper portion of the drain/cleanout cover assembly from the cover base of the drain/cleanout cover assembly to expose the void space, and positioning the finish drain/cleanout at a desired height.
Patent CA-3178969-A1 (CA)
Inventor: FORTHOFFER DANIEL WILLIAM
IPC: B60W40/12
Filed: 2022-10-12
Abstract: A tandem position sensing system includes a range sensor configured to emit a signal toward a sliding tandem and to measure a distance between the range sensor and the sliding tandem, a sensor housing configured to house the range sensor, the sensor housing having a first opening through which the range sensor is configured to emit the signal, and a coupling member attached to the sensor housing and configured to couple the range sensor housing to a body of a trailer or a chassis.
Patent CA-3179530-A1 (CA)
Title: Pressure-regulating fluid transfer systems and methods
Inventor: CHHIKARA BHUPINDER
IPC: A61M5/32
Filed: 2014-07-15
Abstract: A syringe assembly configured to regulate pressure in a container, the syringe assembly comprising: a housing comprising a distal portion; a plunger slidably received in the housing, the plunger comprising a distal plunger seal, a proximal plunger seal, and an inner channel; a first reservoir located in a distal portion of the inner channel of the plunger and between the distal plunger seal and the proximal plunger seal; a second reservoir located in the distal portion of the housing; the distal plunger seal sealingly engaged with an inner surface of the housing;  and the proximal plunger seal configured to slide within the inner channel of the plunger and relative to the distal plunger seal, whereby the sliding of the proximal plunger seal varies a volume of the first reservoir inside of the plunger.
Patent CA-3179958-A1 (CA)
Inventor: LE BIHAN THIERRY
IPC: C07K16/00
Filed: 2021-06-10
Abstract: Methods and reagents to obtaining a sample enriched in peptides comprising the third complementarity-determining region of the heavy chain (CDRH3) of immunoglobulins, such as IgGs, are described. These methods are based on the use of targeted protease digestion of immunoglobulins and affinity purification of CDRH3 peptides using specific antibodies. Such methods and reagents are useful for analyzing the immunoglobulin repertoire.
Patent CA-3183092-A1 (CA)
Inventor: ARMITAGE GRAHAM MARK
IPC: A45F3/04
Filed: 2022-12-02
Abstract: A backpack includes right and left shoulder straps that each respectively follows a path starting with a fixed connection at a bottom corner of a back panel. A padded portion extends upwards and then proceeds through an upper ring on the same side of the backpack. The strap then extends back down while crossing over to another fixed connection to a bottom comer on the other side of the back panel. At the top ring, the strap is merely guided back down and is not fixed relative to the ring. Curved frame stays on the left, right and bottom of the back panel have concave shape toward the user. A hipbelt attaches to the backpack with pin connections to allow rotational motion therebetween while preventing lateral motion. Outside straps reduce strain on the backpack fabric and side pockets are passthrough for insertion of objects therebetween while still allowing pocket usage.
Patent CA-3183162-A1 (CA)
Inventor: SGANGA JAKE ANTHONY
IPC: A61B34/10
Filed: 2021-06-17
Abstract: System for guiding an instrument within a vascular network of a patient are disclosed. In some embodiments, the system receives a medical image from a medical imaging device and identifies a distal tip and a direction the instrument in the image. The system may then determine a waypoint for the distal tip of the instrument based at least in part on the position and direction of the distal tip of the instrument. The system may then generate a trajectory command for moving the instrument through the vascular network from the current position to the waypoint. The system may operate in a closed loop. The system may provide the trajectory command to a robotic medical system configured to move the instrument according to the command.
Patent CA-3184305-A1 (CA)
Title: Mixed fleet capable lubricating compositions
Inventor: GILES NICHOLAS
IPC: C10M159/20
Filed: 2022-12-15
Abstract: This disclosure describes lubricating additives and lubricants including such additives suitable for and/or configured for mixed fleet use and, for instance, additives and lubricants that satisfy performance standards for typical spark ignition passenger car lubricants as well as performance standards for lubricants suitable for typical compression ignition heavy duty engine applications.
Patent CA-3185503-A1 (CA)
Title: Activateur de nrf2 destine a etre utilise dans le traitement de cardiomyopathies dilatees
Inventor: RICHARD ISABELLE
IPC: A61K48/00
Filed: 2021-06-09
Abstract: La présente invention concerne le traitement de cardiomyopathies dilatées, en particulier l'utilisation d'un activateur de NRF2.