baber/WOPTO huggingface dataset:
Patent CA-2649577-A1 (CA)
Title: Benzamide glucokinase activators
Inventor: MURRAY ANTHONY
IPC: A61K31/427
Filed: 2007-04-27
Abstract: The present invention relates to N-heteroaryl-benzamides of the formula (I), pharmaceutical compositions comprising the same, and methods of using the same. The N-heteroaryl-benzamides are useful as glucokinase activators.
Patent CA-2651692-A1 (CA)
Title: Safety coatings
Inventor: WHITELEY REGINALD KEITH
IPC: C09D133/10
Filed: 2007-05-02
Abstract: The invention relates to coating compositions, in particular anti-slip floor coating compositions that contain a crystalline polymeric material in solution that crystallises as the coating cures leading to the formation of hard polymeric crystals within the cured coating composition. The invention also relates to methods of making these compositions and uses thereof.
Patent CA-2652648-A1 (CA)
Title: Dihydrodiazepines useful as inhibitors of protein kinases
Inventor: CHARRIER JEAN-DAMIEN
IPC: A61K31/4545
Filed: 2007-02-13
Abstract: The present invention relates to compounds useful as inhibitors of protei n kinase. The invention also provides pharmaceutically acceptable compositio ns comprising said compounds and methods of using the compositions in the tr eatment of various disease, conditions, or disorders. The invention also pro vides processes for preparing compounds of the inventions.
Patent CA-2654103-A1 (CA)
Inventor: IBANEZ SAPINA MIGUEL
IPC: F16K43/00
Filed: 2009-02-13
Abstract: This liquid distributor valve comprises a compartmented base body (1) being provided with a cover (3) and with several outlets (2) and one inlet (4), a rotatable obturator bell (5) being innerly arranged and having a shaft (7) projecting through said cover (3) and being governed by an externally arranged electronic control (6) being made up by an independent assembly being adapted to be fitted onto the base body (1). This valve is characterised in that the actuation on the shaft (7) of the obturator bell from the gearmotor (8) of the externally arranged electronic control (6) is carried out through a pinion (9) being driven by the shaft of the gearmotor (8) and enmeshed with a gear wheel (10) being linked to the shaft (7) of the obturator bell (5). The linking between the gear wheel (10) and the shaft (7) of the obturator bell (5) is accomplished by means of a tubular body (11) having an external thread (12) matching the thread (13) being provided in the inside of the neck (14) forming an extension of the gear wheel (10).
Patent CA-2656604-A1 (CA)
Inventor: MACHIDA HARUHIKO
IPC: A61K47/26
Filed: 2007-06-28
Abstract: Disclosed is a pharmaceutical composition for injection purposes, which comprises WAP-8294A2 (a depsipeptide-type antibiotic) as an active ingredient, which is stable, and which contains WAP-8294A2 in a high concentration. Specifically, disclosed is a pharmaceutical composition for injection purposes, which comprises WAP-8294A2 having the structure represented by the formula (1) as an active ingredient and 2-hydroxypropyl-.beta.-cyclodextrin or .beta.-cyclodextrin as a stabilizing agent or a solubilizer, and whose pH value is not adjusted. Also disclosed is a solution for injection comprising WAP-8294A2,which can be prepared by mixing the pharmaceutical composition with a pH-adjusting agent comprising a solution containing disodium hydrogen phosphate, monosodium dihydrogen phosphate and sodium hydroxide and an infusion or a diluent such as dextrose just before use. (1)
Patent CA-2657114-A1 (CA)
Inventor: OHTA KAZUHIDE
IPC: A61K31/4709
Filed: 2007-07-18
Abstract: The present invention provides an NF- .kappa.B inhibitor. The NF- .kappa.B inhibitor of the present invention contains a carbostyril compound represented by General Formula (1) or a salt thereof, wherein A is a direct bond, a lower alkylene group, or a lower alkylidene group; X is an oxygen atom or a sulfur atom; R4 and R5 each represent a hydrogen atom; the bond between the 3 and 4 positions of the carbostyril skeleton is a single bond or a double bond; R1 is a hydrogen atom, etc; R2 is a hydrogen atom, etc; and R3 is a hydrogen atom, etc.
Patent CA-2659724-A1 (CA)
Inventor: MARSCHKE CARL R
IPC: B31D3/00
Filed: 2007-06-28
Abstract: A continuous, fully automated and highly productive system for the produc tion of open core elements utilizes various formations of fluted input webs which are cut into strips, glued, cross-transferred, and serially upended fo r placement against preceding strips to build up an open core element. The o pen core elements are useful in the manufacture of structural members such a s doors, floor panels and to all panels. Also disclosed is a fluting apparat us effective for providing large pitch flutes for the input webs used in for ming the core elements. A glue machine that utilizes a glue roll as the only moving part operates in conjunction with the ganged positive displacement a dhesive pump to supply liquid adhesive for application to the flute tips to any of the various glue application stations in the system.
Patent CA-2660516-A1 (CA)
Title: Treating or preventing cancers over-expressing reg4 or kiaa0101
Inventor: NAKAGAWA HIDEWAKI
IPC: A61P35/00
Filed: 2007-08-08
Abstract: The invention features a method for inhibiting growth of a cancer cell by contacting the cell with a composition of an siRNA that inhibits expression of REG4 or KIAA0101. Methods of treating cancer are also within the invention. The invention also features products, including nucleic acid sequences and vectors as well as to compositions comprising them, useful in the provided methods. The invention also provides a method for inhibiting of tumor cell, for example pancreatic cancer cell, prostatic cancer cell, breast cancer cell, and bladder cancer cell, particularly pancreatic ductal adenocarcinoma (PDAC) by inhibiting REG4 gene. The present invention also relates to methods of treating or preventing PDAC in a subject comprising the step of administering to said subject a pharmaceutically effective amount of an antibody or fragment thereof that binds to a protein encoded by REG4. The present invention also relates to methods of diagnosing chemo-radiation therapeutic resistance of a cancer. The present invention also provides therapeutic agents or methods for treating cancer using the polypeptides. The polypeptides of the present invention are composed of an amino acid sequence which comprises polypeptide which comprises QKGIGEFF/SEQ ID NO: 21. The polypeptides of the present invention can be introduced into cancer cells by modifying the polypeptides with transfection agents such as poly-arginine.
Patent CA-2664268-A1 (CA)
Title: Diaryl oxadiazol derivatives
Inventor: LEWIS IAN
IPC: A61K31/4245
Filed: 2007-09-27
Abstract: Disclosed are polycyclic compounds of the following formula (I) and their use as anti-inflammatory and immunosuppressive agents.
Patent CA-2664665-A1 (CA)
Title: Environmentally improved rearview mirror assemblies
Inventor: STRAY JOEL A
IPC: G02B5/08
Filed: 2007-09-24
Abstract: Environmentally improved rearview mirror assemblies are provided which incorporate a reflective element with variable reflectance. In one embodiment, the environmentally improved rearview mirror assembly is substantially free of cadmium (Cd). In another embodiment, the environmentally improved rearview mirror assembly is substantially free of lead (Pb). In yet another embodiment, the environmentally improved rearview mirror assembly is substantially free of mercury (Hg). In a further embodiment, the environmentally improved rearview mirror assembly is substantially free of poly-vinyl-chloride (PVC). In yet a further embodiment, the environmentally improved rearview mirror assembly is substantially free of halogen producing chemicals such as bromine (Br).
Patent CA-2666421-A1 (CA)
Title: Cooling fan gordon switch
Inventor: GORDON MICHAEL HUGH
IPC: B60K37/06
Filed: 2009-05-14
Abstract: This invention relates to the automatic turn on and automatic turn off, of the motor, that spins the two cooling, fans or the one cooling fan under the hood of an automobile or under the hood of another type of motor vehicle.   Things in a vehicle or things on a vehicle that become almost as hot as fire or as hot as fire, should be under a certain amount of consistant and constant central.  This invention will help eliminate the overheating of parts because of a lack of proper hot air circulation under the hood, and it will probably in some instances help the driver recognize changes in the cooling patterns.
Patent CA-2667374-A1 (CA)
Inventor: ELLIOTT BRIAN
IPC: C12Q1/68
Filed: 2007-10-23
Abstract: The invention provides a method for evaluating the accuracy of an oligonucleotide sample, specifically a sample containing a variety of oligonucleotides of potentially varying size and sequence. The method provides a fingerprint that can be used to evaluate the accuracy of a multi-oligonucleotide sample whether or not the sample contains differing oligonucleotides that have the same or about the same molecular weight.
Patent CA-2670056-A1 (CA)
Title: Wireless local area network hotspot registration
Inventor: REIF ALEXANDER J
IPC: H04L12/28
Filed: 2007-11-20
Abstract: A wireless local area network "WLAN" client device that has just connected to a WLAN detects that the WLAN is offered by a hotspot, where access to a public network is provided by the WLAN via a gateway. A browser application of the WLAN client device is launched, either automatically or in response to receiving an indication via a user input element of the WLAN client device to register at the hotspot. The browser application is launched with an Internet Protocol address that ought to trigger an Internet Protocol filtering rule of the gateway.
Patent CA-2670071-A1 (CA)
Inventor: NAKAHATA SEIJI
IPC: H01L21/20
Filed: 2002-10-01
Abstract: A low dislocation density GaN single crystal substrate is made by forming a seed mask having parallel stripes regularly and periodically aligning on an undersubstrate, growing a GaN crystal on a facet-growth condition, forming repetitions of parallel facet hills and facet valleys rooted upon the mask stripes, maintaining the facet hills and facet valleys, producing voluminous defect accumulating regions (H) accompanying the valleys, yielding low dislocation single crystal regions (Z) following the facets, making C-plane growth regions (Y) following flat tops between the facets, gathering dislocations on the facets into the valleys by the action of the growing facets, reducing dislocations in the low dislocation single crystal regions (Z) and the C-plane growth regions (Y), and accumulating the dislocations in cores (S) or interfaces (K) of the voluminous defect accumulating regions (H).
Patent CA-2673787-A1 (CA)
Title: Device for storing luggage for a public transport vehicle
Inventor: ALBERTI JEROME
IPC: B60N2/90
Filed: 2007-12-27
Abstract: The invention relates to a device (1) for storing luggage for a public transport vehicle, that comprises a base defining a reference surface, a first bearing surface (3'), a second bearing surface (4'), each of the bearing surfaces (3', 4') being essentially planar and inclined relative to said reference surface, and both bearing surfaces (3', 4') converging towards said reference surface and defining a storage volume (5) capable of receiving a piece of luggage.
Patent CA-2675553-A1 (CA)
Inventor: FROHBERG CLAUS
IPC: A23L29/20
Filed: 2008-01-23
Abstract: The present invention relates to genetically modified monocotyledonous plant cells and plants whose starch has an apparent amylose content of less than 5% by weight and an increased activity of a protein with the activity of a starch synthase Il and an increased activity of a protein with the activity of a glucan, water dikinase. Such plants synthesize starch with an increased hot-water swelling power. Methods and processes for the generation/preparation of these plant cells, plants, starches and flours are likewise subject matter of the present invention.
Patent CA-2675762-A1 (CA)
Title: Administration d'agents bloquant et/ou favorisant l'ethylene
Inventor: NEWSHAM MARK D
IPC: A23L5/49
Filed: 2008-01-14
Abstract: La présente invention concerne une composition comprenant un complexe agent bloquant l'éthylène formé à partir du produit d'un agent bloquant l'éthylène et d'un hôte, et d'au moins un polymère soluble dans l'eau, le complexe agent bloquant l'éthylène et l'au moins un polymère soluble dans l'eau étant mélangés.
Patent CA-2676586-A1 (CA)
Title: Montage de machine electrique en tandem
Inventor: BRAND JOSEPH
IPC: H02K1/12
Filed: 2009-08-25
Abstract: Montage de machine électrique en tandem comprenant un rotor externe ayant deux ensembles d'aimants permanents circonférentiels et espacés l'un de l'autre de manière axiale. Le montage comprend aussi un stator interne ayant au moins deux enroulements électriquement autonomes. Les enroulements sont espacés de manière axiale les uns par rapport aux autres et sont placés par rapport aux ensembles d'aimants de manière à être couplés magnétiquement à un ensemble respectif d'aimants permanents pendant la rotation du rotor. Un rotor et le stator sont fournis en deux pièces distinctes, chaque pièce étant soutenue sur les côtés axiaux opposés de la machine électrique l'un par rapport à l'autre. L'autre rotor et le stator sont soutenus essentiellement au centre des deux pièces.
Patent CA-2678165-A1 (CA)
Title: Crystalline forms of (6r)-l-erythro-tetrahydrobiopterin dihydrochloride
Inventor: GROEHN VIOLA
IPC: A61P25/00
Filed: 2004-11-17
Abstract: Crystal forms of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride, hydrates and solvates and processes for their preparation are provided. These crystal forms are suitable for solid formulations.
Patent CA-2678188-A1 (CA)
Inventor: SCHMITT RANDALL PAUL
IPC: E03C1/06
Filed: 2008-02-19
Abstract: A fluid delivery apparatus (12) including an energy harvesting device (48) to generate energy for communicating with a fluid control device (18, 20).
Patent CA-2679078-A1 (CA)
Inventor: LAW BARNABY
IPC: B29C70/34
Filed: 2008-03-26
Abstract: This invention provides a method for producing a structural component, particularly in the aerospace sector. An unhardened prepreg fabric (6) is formed from a composite fibre material, hardenable at a first hardening temperature, into a predetermined shape. The unhardened prepreg fabric (6) is then connected to at least one hardening part (12, 13) of a composite fibre material partially hardened at a second hardening temperature for holding the unhardened prepreg fabric (6) in the predetermined shape, wherein the second hardening temperature is lower than the first hardening temperature. In a further method step the unhardened prepreg fabric (6) connected to the at least one holding part (12, 13) is hardened at the first hardening temperature to form the structural component. The idea on which this invention is based consists in replacing expensive tools of special steel previously used for holding dimensionally unstable prepreg fabrics with at least one holding part (12, 13) of composite fibre materials, wherein the at least one holding part (12, 13) has a lower hardening temperature than the prepreg fabric (6), and can therefore be produced with a lower cost tool.
Patent CA-2681896-A1 (CA)
Inventor: CHENG PO WEN
IPC: F03D11/00
Filed: 2009-10-08
Abstract: A wireless information system for wind turbine components of a wind turbine (100) is disclosed. The wireless information system includes a radio-frequency identification (RFID) tag (200) attached to a wind turbine component. The RFID tag (200) contains component information such as identification, commissioning date, and maintenance information. The system allows the components to be identified and/or verified by a technician. The technician may use a handheld device, which permits the RFID  tag to be read at various locations.
Patent CA-2684611-A1 (CA)
Title: Metal aminoboranes
Inventor: SEMELSBERGER TROY ALLEN
IPC: C01B6/10
Filed: 2008-05-07
Abstract: Metal aminoboranes of the formula M(NH2BH3)n have been synthesized. Metal aminoboranes are hydrogen storage materials. Metal aminoboranes are also precursors for synthesizing other metal aminoboranes. Metal aminoboranes can be dehydrogenated to form hydrogen and a reaction product. The reaction product can react with hydrogen to form a hydrogen storage material. Metal aminoboranes can be included in a kit.
Patent CA-2686756-A1 (CA)
Inventor: SANDHU HARPREET K
IPC: A61K9/14
Filed: 2008-04-30
Abstract: The invention relates to solid dispersions of poorly soluble compounds formed by co-precipitation and hot melt extrusion, resulting in improved stability and bioavailability. The invention also relates to hot melt extrusion processes used to prepare such solid dispersions.
Patent CA-2688512-A1 (CA)
Title: An apparatus for forming spaced intervals in a stuffed casing and method thereof
Inventor: MALENKE MARK ERVIN
IPC: A22C11/10
Filed: 2009-12-16
Abstract: A flexible, composite unitary belt for forming spaced intervals in a stuffed casing, and method therefore, the belt cooperating*with another belt to pinch the stuffed casing. The belt comprises a body forming a continuous loop and having at least one embedded flexible reinforcing member extending throughout. Additionally, the belt has at least one pinching member extending outwardly from the body and positioned to cooperate with a pinching member of another belt to pinch the stuffed casing when fed between the belts and pinched by the pinching members.
Patent CA-2688858-A1 (CA)
Inventor: CLEMENTE RUDY
IPC: A61Q19/04
Filed: 2009-12-18
Abstract: The present invention relates to a composition for darkening the skin.   The composition includes a self-tanning agent, and a plant extract selected from the group consisting of extract of pre-germinated soy seeds, walnut seed extract, mugwort extract, and combinations thereof. In another aspect, a method of darkening the skin includes topically applying the above composition to the skin.
Patent CA-2690056-A1 (CA)
Title: Rage fusion proteins
Inventor: BLECK GREGORY T
IPC: C07K14/00
Filed: 2008-06-13
Abstract: The present invention provides novel therapeutics and methods of treatment for diseases associated with activation of the advanced glycatio.pi. endproducts receptor (RAGE).
Patent CA-2691961-A1 (CA)
Inventor: JOERGENSEN MORTEN
IPC: A61P25/00
Filed: 2008-08-28
Abstract: The present invention relates to novel catecholamine derivatives of Formu la I, to processes for their preparation, pharmaceuticalcompositions contain ing them and to their use in therapy.
Patent CA-2694348-A1 (CA)
Inventor: BENZ GERHARD
IPC: B63B39/06
Filed: 2008-07-30
Abstract: It is an object of the invention to create a sailing yacht having a heeling hull body part and a non-heeling hull body part, which sailing yacht, with regard to the heeling hull body part, can be sailed in the conventional manner and, with regard to the non-heeling hull body part, ensures all the clear advantages of a substantially horizontally-remaining alignment when used preferably as a cabin, galley and/or cockpit, and which sailing yacht thereby offers the greatest possible comfort when sailing, in particular when residing below deck, and can be converted in a simple manner into a pure motorboat. Said object is achieved according to the invention in that both the mast (2) and also the keel (3) are in each case arranged so as to be rigidly connected to the first, heeling hull body part (1.1), and in that the first hull body part (1.1) which supports the mast-keel combination (2, 3) is articulatedly connected to the non-heeling, second hull body part (1.2), which does not support a mast-keel combination, by means of a revolute joint (4), which is preferably formed as a double-ring rolling bearing, so as to be pivotable by a rotational angle (a) about the bow-stern axis (L).
Patent CA-2694732-A1 (CA)
Inventor: DO ROBERT
IPC: E21B47/10
Filed: 2008-08-13
Abstract: A method of measuring a dry gas flow from hydrocarbon wells. The hydrocarbon wells produce a stream which contains liquids and natural gas. The method comprises providing a differential flow measurement device (orifice) located at a well site containing the hydrocarbon wells. The method further includes testing the stream for gas composition and physical characteristics. Additionally, the method comprises measuring a static temperature (T) of the stream, measuring a static pressure (Ps), and measuring a pressure differential (dP) in the differential flow measurement device (orifice). The method includes computing the liquid-gas ratio (LGR) of the stream, computing the wet gas flow rate (Qw) of the stream, computing a first dry gas flow rate (Qd1) and a second dry gas flow rate and utilizing a iterative process to correct and obtain the dry gas flow rate. The data may be transmitted to another location.
Patent CA-2694946-A1 (CA)
Inventor: WIENER EITAN T
IPC: A61B17/32
Filed: 2008-07-31
Abstract: A surgical instrument. The surgical instrument may comprise a transducer and an end effector. The transducer may be configured to provide vibrations along a longitudinal axis at a predetermined frequency and may comprise a piezoelectric stack positioned along the longitudinal axis. The transducer also may comprise a first metallic end mass positioned along the longitudinal axis adjacent a first end of the piezoelectric stack and a second metallic end mass positioned along the longitudinal axis adjacent a second end of the piezoelectric stack. The length of the transducer may be greater than or equal to 1/4 of one wavelength and less than 1/2 of one wavelength. The end effector may be coupled to the transducer and may extend along the longitudinal axis. The length of the transducer and the end effector may be a multiple of 1/2 of one wavelength.
Patent CA-2695648-A1 (CA)
Inventor: BEADLE EDWARD R
IPC: H04L1/00
Filed: 2008-08-26
Abstract: A system estimates noise power in a scalar, multi-signal communications channel. A data sampler collects N data samples from communications signals received from the communications channel.  A module forms a covariance matrix of the N  data samples based on a model order estimate. A module also computes the eigenvalue decomposition of the covariance matrix and ranks resultant eigenvalues from the minimum to the maximum for determining the noise power.
Patent CA-2697227-A1 (CA)
Inventor: STONE JEFFREY W
IPC: F41A5/18
Filed: 2008-08-28
Abstract: A piston assembly (200) is provided for a gas-operated firearm of the type having a chamber and a barrel. The pis-ton assembly includes a gas expansion housing (217) and a piston (232) mounted within the gas expansion housing. An annular recess (235) is formed in the outer wall of the piston to receive exhaust gases diverted from the barrel upon firing of the firearm.  At least one longitudinally extending groove (237) extends from the annular recess to the head of the piston and forms a pathway for diverting the exhaust gases to the head of the piston. During firing, pressurized gases are diverted into the annular recess and expand longitudinally from the annular recess to the piston head, whereupon the pressurized exhaust gas drives the gas piston rearwardly along the housing.
Patent CA-2697929-A1 (CA)
Inventor: LINZ WOLFGANG
IPC: C12N9/06
Filed: 2008-08-20
Abstract: The invention relates to the use of an urate oxidase, preferably recombinant urate oxidase, for example Rasburicase, for producing a medicament for the treatment or prophylaxis of disorders or indirect sequelae of the heart caused by ischemic or reperfusion events, for example during and after cardiac surgery like CABG (coronary artery bypass graft), PCI (percutaneous coronary intervention), transplantation, post myocardial infarction and for the treatment or prophylaxis of coronary artery disease or heart failure, for example congestive heart failure.