baber/WOPTO huggingface dataset:
Patent EC-SP11011534-A (EC)
Title: 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il]octano- o heptano-nitrilo como inhibidores de jak
Inventor: RODGERS JAMES D
IPC: A61K31/519
Filed: 2011-12-15
Abstract: La presente invención se relaciona con los inhibidores de la Janus quinasa (JAK) 3-[4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il]octanonitrilo ó 3-[4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il]heptanonitrilo, así como con sus composiciones y métodos de uso, los cuales son útiles en el tratamiento de enfermedades asociadas a la JAK incluyendo, por ejemplo, trastornos inflamatorios y autoinmunes, trastornos de la piel, cáncer y otras enfermedades.
Patent GB-189704416-A (GB)
Title: New or Improved Machine for Pressing Dry or Moist Substances.
Inventor: FICKELSCHEER CARL
Filed: 1897-02-18
Granted: 1897-04-17
Abstract: 4416. Fickelscheer, C., Rahmer, S., and Kr³ger, G. Feb. 18. Moulding cocoa, coffee, tea, &c.-The dry or moist powdered substance is fed through a hole in a press head i to moulds in an intermittently-rotating plate m by a hopper r. A vertical spindle in the hopper is rotated by an endless band s and bevelwheels s<1>, and carries radial arms for agitating the material. A helical spring on radial arms at the bottom of the hopper secures the complete filling of the moulds by springing, as it passes, into the hole in the press head i. A plate l<1> carries a series of studs q<1> gradually increasing in height, and these studs come in contact with the stems of pressing-stamps so that the pressures on the substances are increased step by step. The head i is attached to vertical rods k connected to links g of a toggle joint g, g<1> operated by an eccentric f. The link g<1> is connected to the plate l<1>, and the head and plate are brought together when the toggle links come into line. The mould plate is rotated on a central stud by a ratchet-wheel and pawl p and a bell-crank lever o operated by the upward movement of the head. The pressing-plunger, after ejecting the moulded cake from the mould, is forced downwards again by a pin, operated by a cam, adjustable rod t<1>, and lever t.
Patent GB-189705317-A (GB)
Title: Improved Welt Apparatus for Flat Power Knitting Frames.
Inventor: NIEMANN MAX ADOLF
Filed: 1897-02-27
Granted: 1897-05-29
Abstract: 5317. Niemann, M. A. Feb. 27. Straight-bar knitting-machines. - Welting. The cast-on row of loops is engaged with a set of latch needles c on a bar c' guided in ways i, i<1> and moved by a chain k<1> passing over pulleys to a shaft o rotated by a chain and weight. By sliding the part f<2> the length of welt can be adjusted. After a portion of the welt has been knitted, a bar m‹ is placed over the fabric and into the hooks g acted on by springs g<1>, g<2>. When the welt is long enough the bar c<1> enters the top guide i<1> and is shogged till the needles c become opposite the frame needles instead of between them, and the cam shaft is shogged by which the shaft o is rotated by a ratchet and pawl. The bar c<1> is thus drawn up the guide i<1>, Fig. 2, until it falls into the position of Fig. 3, the needles a entering recesses z in the needles c. The sinkers now come forward, and the needle bar a<1> and the rake c' are raised simultaneously, the loops passing on to the frame needles. Springs h press the rake c' into the knee of the guide i<1>, and the weight operating the shaft o lodges on a bracket and does not cause the rake c' to re-descend. The spring g<1> takes up the first part of the leg fabric until the bar m‹ is fixed to the proper takeup roller by india-rubber bands. After a time the bar m‹ is withdrawn and the parts of the welting- apparatus brought to the initial position. The whole welt is thus made without stopping the machine.
Patent GB-189707455-A (GB)
Title: Improvements in the Method of and Apparatus for the Effectual Comsumption of Smoke from Steam Boilers and other Furnaces.
Inventor: PEARSON JAMES
Filed: 1897-03-23
Granted: 1898-01-29
Abstract: 7455. Pearson, J. March 23. Smoke - consuming.-Air from the ashpit of a steamboiler or other furnace is passed to the flues by way of an aperture A in the firebridge. The amount is regulated by means of a door D operated from the front. The deflector F is also provided.
Patent GB-189711134-A (GB)
Title: Improvements in Machines for Grinding Glass Tubes.
Inventor: HOESEN THEODORE W VAN
Filed: 1897-05-04
Granted: 1897-12-04
Abstract: 11,134. Hoesen, T. W. van, and Wilson, W. W. May 4. Surfacing and polishing.-A machine for grinding the interior surface of glass tubes for levels is shown in sectional elevation in Fig. 2. Two upright frames A form guides for a block D, which carries the tube-holder H, the latter being capable of turning upon the pin g held in suitable brackets on the block D. A balance weight holds up the block D by the cord c. A curved grinding-bar K held in sockets k at the ends of arms L moves backwards and forwards through the glass tube, a reciprocating motion being given to the shaft l by the lever M and connecting-rod N, actuated by a revolving crank or disc O. The dotted lines show a second position of the mechanism. Fig. 15 shows an arrangement of the socket k for taking grinding-bars of different sizes, and two forms of tube holder are shown in Figs. 6 and 11. In the arrangement shown in Fig. 6, two split rings J, J having india rubber linings j, j, surround the tube T, and are gripped by the holder H, which is itself split and can be drawn tight by thumb-screws, not shown. In the arrangement shown in Fig. 11, the tube T is held in a V groove in the part 20 by a curved plate 23, which is pressed up by a screw 24 working in the piece 21, which partly embraces the part 20. The tube may be rotated in the holder by the fingers while the machine is working.
Patent GB-189711879-A (GB)
Title: Improvements in Metallic Packings for Piston Rods and the like.
Inventor: BARKER REUBEN LOWE
Filed: 1897-05-13
Granted: 1897-06-19
Abstract: 11,879. Barker, R. L. May 13. Stuffing-boxes.-Fig. 1 shows a section through the gland with the metallic packing C in elevation ; the packing in one of its forms is shown in crosssection in Fig. 2. The packing consists of two guide-blocks d with two slide-blocks e fitted between them, all shaped and finished to fit the piston-rod b. Each pair is furnished with springs f, j contained in flanged tubes or sleeves g, k and adjusted by screws h, l. In the form shown in Fig. 4 the packing is pressed against the rod by radial springs o on which rest thimbles n surrounded by a circumferential or belt spring p. Slight modifications in the number and arrangement of the springs may be made in each case.
Patent GB-189713199-A (GB)
Title: Improved Combination Bedroom Furniture.
Inventor: WALKER FREDERICK MOSELEY
Filed: 1897-05-28
Granted: 1898-04-02
Abstract: 13,199. Walker, F. M. May 28. Wardrobes; washstands; tables.-A combination bedroom suite is composed of a wardrobe A and a toilet table B adapted for attachment one to either side of the other. The table forms a washstand and may be furnished with drawers F, commode G, mirror C, and towel rail H.
Patent GB-189715845-A (GB)
Title: Improvements in Taps for Use in Forming Screw-threads in Articles or Objects being Operated upon in Lathes or Screwing Machines or other Machines.
Inventor: KILBURN RICHARD
Filed: 1897-07-03
Granted: 1898-07-02
Abstract: 15,845. Kilburn, R. July 3. Tapping.-Relates to taps for screw-threading articles held in lathes or in screwing or other machines. Figs. 1 and 15 show one form of tap. The dies a slide in dovetail grooves in the holder b. A spring d tends to bring the opposite cutting- edges a<1> closer together so that the tap may be withdrawn from the work without rotating it. The dies are forced outwards into their working position by the inclines e<6>, and rest upon the flats e<1> while working. The parts e<1>, e<6> are made on the forked end of a rod e, which may be slid to and fro in the holder b by a collar f rigidly connected to the rod e by the pin e<3>, which passes through slots in the holder b and socket c. The holder b slides a short distance in the socket c without turning, and the rod e also slides in the socket c against the action of a spring between the collars e', c'. By arranging a suitable fixed stop on the machine the traverse of the socket c, and thus the rod e, may be arrested, while the dies and holder b still go forward until the inner ends of the dies ride over the inclines e<6> and close together, at the same time pushing back the rod e. Figs. 25 and 27 show details of another form of tap in which the dies a are forced out by rotating, instead of sliding, the rod e, which carries cams el for engaging the dies. The rod e is rotated by a collar f, connected by a pin e<3> to the rod. Either one or two projections f may be formed on the collar to engage with a collar or collars g, h, fixed by set-screws to the socket c. This enables the dies to be forced out in steps for making several successive cuts. Fig. 53 shows another form similar to the last, in which four dies alpha are used. The dies are adjusted by turning the rod e by the collar f. The Provisional Specification states that the dies may be held extending outward in different degrees by wedges or the like.
Patent GB-189715899-A (GB)
Title: Improvements in or relating to the Driving Gear of Cycles.
Inventor: LUTHER OSCAR
Filed: 1897-07-03
Granted: 1897-10-30
Abstract: 15,899. Luther, O. July 3. Mounting and securing wheels &c. on shafts.-In the two-speed gearing for cycles shown in Fig. 1, the ball cups 34 and 35 are secured to the driving- wheel hub by right and left hand screw threads 36 and 37, the object being to give greater stability to the chain-wheels 1 and 2 by reducing their bore. The chain-wheels 1 and 2 are carried by flanges 39 and 40 which rest on flanges 38 and 41 formed on the ball cups and wheel hub respectively.
Patent GB-189716052-A (GB)
Title: Improvements in connection with Lamps for Cycles and other Vehicles.
Inventor: PREWETT WILLIAM
Filed: 1897-07-06
Granted: 1897-11-13
Abstract: 16,052. Prewett, W. July 6. Velocipede &c. lamps.-To facilitate the reading of direction-posts, the inspection of the cycle or vehicle, &c., a reflector h is hinged or fixed to the mount e of the side light d, the mount being flanged to permit of its being turned through a complete revolution without becoming detached. When hinged, the reflector is secured in either the open or closed position by means of the wire loop j and the button n. A reflector may be fitted to each side of the lamp.
Patent GB-189718363-A (GB)
Title: Improved Process and Apparatus for Obtaining Ice.
Inventor: BOULT ALFRED JULIUS
Filed: 1897-08-06
Granted: 1897-09-11
Abstract: 18,363. Boult, A. J., [Bechmann, H.]. Aug. 6. I c e - making.- Water is sprayed from pipes, roses, &c. g over bars or matting, such as b, arranged in one or more stories in a frame exposed to a suitable temperature.
Patent GB-189719960-A (GB)
Title: Improvements in Lathes for Making Screws and other Small Articles.
Inventor: WITHERELL GEORGE EVERETT
Filed: 1897-08-31
Granted: 1898-02-26
Abstract: 19,960. Witherill, G. E. Aug. 31. Lathes.-Relates to lathes for making screws and other articles which are provided with a turret or capstan 22, a headstock 6 with a spindle driven by oppositely-rotating loose e pulleys 7 connected to the spindle by a clutch controlled by a lever 8 and cam 9, feeding and chuck opening and closing mechanism 10, 11, 12, 13 operated by a cam 14, and a tool slide 15 reciprocated by levers 16 and cam 17. The turret 22 has a journal extending through the slide 23, and a ratchet-wheel is secured to the lower end of the journal. When the slide 23 is moved away from the work by the cam 25, the ratchet-wheel is engaged by a spring catch in the bed of the machine to rotate the turret one step. The turret is held in its various positions by a spring bolt 39 engaging notches in a ring 37. The bolt 39 is withdrawn as the slide 23 is moved back by an incline 77 on a pivoted spring arm 76 acting on a pin 44 on the bolt. Another bolt 56 having a pin 58 projecting into a slot 60 in the bolt 39 is actuated at the same time, and a pin 57 on this bolt moving in an inclined groove in an arm 46 rotates a ring 45 which clamps the turret on the slide 23. Inclines on the ring 45 are moved from under inclines on a flanged ring 50 secured to the slide 23 to release the turret, leaving it free to be rotated. After the pin 44 has passed the incline 77, the spring bolt 39 is pressed against the turret ready to engage the next notch in the ring 37. The cam 67 then acts on a lever 65 and rocks a spring plunger 70 which presses against the pin 44 to force the bolt 39 home in the notch of the ring 37. The bolt 56 is returned by an arm 66 and rotates the ring 45 to clamp the turret down on the slide, which is again fed forwards to the work. The lever 16 and cam 17 are enclosed in a casing 80 made of two parts connected together and attached to the machine frame. The work can be supported by a plug or centre rest which can rotate in a holder 90 secured in the turret. The holder 90 is provided with a tapering stud, which, to ensure alignment of the work and rest, enters a conical bush in a bracket 87 fixed on the arm 86. The cam shaft 5 is driven by worm gearing from a shaft 2 actuated at different speeds, either by a fast pulley direct, or by a loose pulley 3 and epicyclic gearing.
Patent GB-189722720-A (GB)
Title: An Improved Urn.
Inventor: BASS THOMAS
Filed: 1897-10-04
Granted: 1897-11-20
Abstract: 22,720. Bass, T., and Shenstone, W. H. Oct. 4. Urns.-Urns for refreshment bar s and other places are provided with a constant supply of water, and with means for maintaining the circulation, b y the followingconstruction. Within an ordinary urn casing are mounted upon rods i several receptacles a, a<1>, a<2>, the uppermost of which is connected with the water main by a pipe b and ball cock c, and is fitted with a waste pipe g. The lower receptacles are connected by circulating pipes e, f, and the two upper ones are connected by a water-supply pipe d and by a pipe h which conducts steam into the top receptacle.
Patent GB-189723693-A (GB)
Title: Pressure Reducing Device for Water Taps and other Fluid Discharge Apparatus.
Inventor: SCHERMULY LUDWIG
Filed: 1897-10-14
Granted: 1897-11-27
Abstract: 23,693. Schermuly, L. Oct. 14. Nozzles.-Fig. 2 shows a pressure-reducing attachment for the mouths of fluid-discharge pipes consisting of a sleeve a with a tapered outlet a sieve b mounted in the said sleeve, and a packing-ring c of india-rubber or similar material placed above the said sieves and adapted to slide over the mouth of the discharge pipe.
Patent GB-189730925-A (GB)
Title: Improvements in Optical Instruments.
Inventor: HUET HENRI LOUIS
Filed: 1897-12-31
Granted: 1898-12-17
Abstract: 30,925. Huet, H. L. Dec. 31. Optical instruments; telescopes; telemeters.- Relates to improvements in the prisms described in Specification No. 14,102, A.D. 1897, and in binoculars for receiving the same. The surfaces of the prism are so arranged that an odd number, five or more, of internal reflections takes place, all of them total, the entrance or exit surface itself being employed as a reflecting-face. In the examples shown, there are five reflections for erecting the image, while by using the form shown in Fig. 6, considerable stereoscopic effect is obtained. Reversal of the image may be produced, as described in the prior Specification, by the addition of a right-angled prism. The binocular, Fig. 8, is of a flattened shape, the prism being mounted in bars c, d, the latter fitted in grooves in the glass and acting as diaphragms. To adapt the width of the instrument to the user's eyes, one barrel can be moved laterally with respect to the other on telescopic slides g, h, i by means of a rack and pinion operated by the milled head j. A screw focussing-adjustment is worked by the milled head r. In a different form, not adapted for stereoscopic effect, there is a rapid draw-out movement of the eye-pieces. A double refraction prism may be fitted to the binocular in a known manner, to enable it to be used for stadiometric telemetry.
Patent GB-189800132-A (GB)
Title: Improvements in or connected with the Driving Mechanism of Cycles.
Inventor: PRICE JAMES
Filed: 1898-01-03
Granted: 1899-04-01
Abstract: 132. Price, J. Jan. 3. Driving-mechanism; clutches.-Relates to clutch arrangements to allow the rear wheel to run free so that the pedals serve as foot-rests, whilst backward as well as forward pedalling is permitted. The chain-wheel d is mounted loosely on shoulders i, i on the rear-wheel hub, and is formed with recesses d<1>, d<2> to receive the ends of pawls f, f<1> pivoted to a trough-shaped ring e encircling the hub. The pawls are arranged as shown. Forward pedalling causes the incline d<3> to act on the pawl f so to cause the band to grip the hub, and backward pedalling causes the incline d' to similarly act on the pawl f<1> and lock the band to the hub. A pin g<1>, carried by a spring g fixed to the chain-wheel, when depressed by the driving-chain causes the end of the spring to engage a projection h on the band so as to hold both pawls out of action. The recesses d<1>, d' may be replaced by cams on the chain-wheel, and a segmental ring may be used in place of the ring e.
Patent GB-189800431-A (GB)
Title: Improvements in Making Cop Tubes and in Machinery and Arrangements for the purpose.
Inventor: SWAILES JOSEPH BRIGGS
Filed: 1898-01-06
Granted: 1898-12-03
Abstract: 431. Swailes, J. B., Swailes, G., and Swalles, J. B. Jan. 6. Paper tubes.-Relates to the manufacture of cop tubes. The tubes are marked, during the process of manufacture, in such a manner that the marks can be seen either on the interior or exterior of the tube, or so that they are hidden by the coils of the tubes and can be seen only by cutting open or uncoiling the tubes. The marks may be made either on the inside or the outside of the paper strip, either before or during the coiling operation, and may be made by printing, embossing, punching, &c. Fig. 3 shows apparatus comprising two stamping-arrangements e<3>, one on each side of the web of paper. The sliding dies e<2>, provided with suitable inking-rollers e<4>, operate against the blocks e, over which the paper travels in the manner shown. The paper passes thence to the pasting- roller g, the continuously-rotating feed-rollers h, h<1>, and the intermittently-rotating feed-rollers h<2>, h<3> of the cop-tube making machine. Between the stamping-apparatus and the pasting-roller, the paper passes over a roller f carried by a camoperated or spring lever in order to allow of a slight dwell or stoppage of the paper strip during the stamping operation. In this case a spring presser may be fitted upon the slide e<2> to hold the paper against a block e during the stamping operation. Arrangements of rollers may be used instead of reciprocating dies. To equalize the tension between the continuously-rotating and the intermittently-rotating feed-rollers, the paper strip may be caused) to pass over a roller carried by spring levers in a similar manner to the roller f. When the marks are produced during the operation of coiling the strip of paper into a tube, the apparatus used comprises sectors having the device produced on the edges thereof, which are rotated intermittently by segmental gearing.
Patent GB-189803407-A (GB)
Title: Improvements in Scuppers especially applicable to Sponsons.
Inventor: PRESTON EDWIN JAMES
Filed: 1898-02-10
Granted: 1898-03-26
Abstract: 3407. Preston, E. J. Feb. 10. Water-escape ports.-An improved scupper is described of a form to keep out the inrush of the sea and specially suitable for sponsons and the like. The scupper is covered inside by a valved or grated lid D, and terminates outside in an annular opening A<5> bell-shaped in vertical section.
Patent GB-189806643-A (GB)
Title: A Novel Arrangement of Curtain Rods.
Inventor: CHOLET JULES HIPPOLYTE
Filed: 1898-03-18
Granted: 1898-06-25
Abstract: 6643. Cholet, J. H. Sept. 18, A.D. 1897, [date claimed under Sec. 103 of Patents &c. Act, A.D. 1883]. Curtains, drawing and suspending.-The curtain is suspended by rings on a rod b carried on brackets, Fig. 2. A right and left handed screw d carried in the brackets engages two nuts f, g secured to the curtains by screws passing through holes therein. The ends of the curtains are secured to the brackets by pins o engaging holes in the curtain, caps p being then screwed on. The operating-chain h passes round a pinion i on the screw d and round a pulley j in bearings k on a screwed rod m passing through a piece l fixed to the wall.
Patent GB-189808809-A (GB)
Title: An Improved Cycle Handle.
Inventor: ROWTHORN WILLIAM
Filed: 1898-04-15
Granted: 1899-02-18
Abstract: 8809. Rowthorn, W. April 15. Handles.-The handle consists of a casting a, preferably of aluminium, which is formed with a bell mouth a<2> and is perforated to allow air to pass through it. It is secured to the handle-bar by a square projection on its end engaging in a recess in a plug d in the end of the bar, the parts being fixed by a screw b. Ribs e support the inner end. The handle is covered with leather, felt, &c. k.
Patent GB-189819223-A (GB)
Title: Improvements in Flexible Handled Hand Stamps.
Inventor: SMITH RICHARD HALE
Filed: 1898-09-09
Granted: 1899-01-21
Abstract: 19,223. Smith, R. H. March 15, [date applied for under Sec. 103 of Patents &c. Act, A.D. 1883]. Hand-stamps.-A rubber hand-stamp, having a flexible connection between the handle and type-holder, comprises a ferrule or like tubular piece c secured to the typeholder b and formed with a flange f on either side of which is a cushion g, preferably made of spongy rubber. The handle d may be secured to the holder by a screw e. In a modification, the tubular piece is set into the holder, and, in another modification, the tubular piece is made in three parts. In a third modification, two thin plates, which take the place of the flange f, are secured to the holder and enter a circumferential groove in the cushion. In another form of hand-stamp, the holder is formed with a recess containing the cushion within which is a plate secured to the handle by means of a stem, and, in a modification of this form, the holder is solid and the cushion is held against its upper surface by a casing secured to the holder.
Patent GB-189821084-A (GB)
Title: Improved Receiver for Liquefied Gas or Gas under Pressure.
Inventor: THOFEHRN HERMANN GEORGES CHRIS
Filed: 1898-10-06
Granted: 1899-08-26
Abstract: 21,084. Thofehrn, H. G. C. Oct. 6. Storing under pressure.-One or both ends of the vessel have dished covers B welded into them which receive and protect the valves. The vessel may have a non-corrosive lining it is provided with a safety-valve and a pressure-reducing valve, both of which are similarly constructed, the reducing-valve being fitted with a stop valve in addition. In Fig. 5, the valve s is normally closed by springs i and an adjustable spring g, which are compressed by an excessive pressure acting on the top of a diaphragm and allow the valve to open and the gas to escape from the holes or a nozzle o. A diaphragm may be substituted for the springs i ; or differential pistons for springs only may be used.