baber/WOPTO huggingface dataset:
Patent CA-2516942-A1 (CA)
Title: Use of quinazoline derivatives or other compounds for inhibiting dihydrofolate reduxtase; screening assay for the identification of novel therapeutics and their cellular targets
Inventor: BROWN ERIC D
IPC: A61K31/517
Filed: 2004-02-04
Abstract: A novel screening assay for identifying therapeutic agents and their cellular targets is described. The assay is useful in developing new antibacterial, antifungal, antiparasitic and anti cancer therapeutics. New inhibitors of dihydrofolate reductase (DHFR) have been identified using the assay of the present invention. Methods of treating diseases that benefit from an inhibition of DHFR are also described.
Patent CA-2522021-A1 (CA)
Title: Vessel occluding material extractor
Inventor: WEBER JAN
IPC: A61F2/01
Filed: 2004-04-09
Abstract: Methods, devices, and systems for extracting vessel occluding material are provided. An embodiment of a vessel occluding material extractor includes a host structure, a plurality of expandable members, a slide mechanism, and a circumferential member. The host structure has an elongate axis. The expandable members are connected to the host structure arrayed radially around the elongate axis. The slide mechanism is connected to the expandable members and adjacent the host structure, and is slidable in the direction of the elongate axis. The circumferential member is connected to the expandable members between the connection of the slide mechanism and the host structure to the expandable members.
Patent CA-2522193-A1 (CA)
Inventor: BHATIA RAVIDEEP
IPC: H04L12/56
Filed: 2005-10-05
Abstract: A home agent preference control node gathers information regarding available home agents in a given network. This information includes both information regarding present availability and other information (for example, other information as may pertain the relative availability of one home agent with respect to another). The home agent preference control node utilizes such information to determine a respective preference value for at least some, and preferably all of the network's home agents. Following communication of a resultant list that comprises, at least in part, such preference values, the home agents are then able to respond to home agent discovery inquiries from a mobile node with this information. This, in turn, facilitates selection by the mobile node of a home agent that likely represents at least a relatively efficient distribution of system resources.
Patent CA-2523222-A1 (CA)
Title: Improved modular tower structure for eolic turbines and other applications
Inventor: FERNANDEZ GOMEZ MIGUEL ANGEL
IPC: F03D11/04
Filed: 2005-10-11
Abstract: Improved concrete, metallic and/or mixed, modular tower structure, for eolic turbines and other applications, made up of a plurality of prefabricated concrete, metallic and/or mixed elements with smooth, rough and stamped surface textures. Each tower (1) is divided into horizontal and vertical sections, where the elements (2) are formed by prefabricated concrete, metallic and/or mixed elements which are partial segments (3) of a revolution surface with a straight or curved generatrix. Those segments are linked by different means, by flanges (5, 6) made up by an internal rim (4) on the end edges, or by a set of metallic straps (7). The present invention facilitates the use of prefabricated concrete structures, metallic or mixed, for this specific purpose, and substantially simplifies the transport, installation and assembly, improving the technical capabilities available at the present State of the Art and with an important reduction in cost.
Patent CA-2524851-A1 (CA)
Inventor: PETERSON DONALD G
IPC: H01M8/00
Filed: 2004-04-02
Abstract: Fabricating roll-good fuel cell material involves laminating first and second bonding material webs having spaced apart windows to first and second surfaces of a fuel cell membrane web. First and second active regions of the membrane web are positioned within the respective bonding material windows. Third and fourth gasket material webs having spaced apart windows are respectively laminated to the bonding material on the first and second membrane web surfaces. The bonding material windows align with the respective gasket material windows so that at least some of the bonding material extends within the respective gasket material windows. Fluid transport layer (FTL) material portions cut from fifth and sixth FTL material webs are laminated to the respective first and second active regions. The FTL material portions are positioned within respective gasket material windows and contact the bonding material extending within the respective gasket material windows.
Patent CA-2525919-A1 (CA)
Inventor: COOK MATTHEW R
IPC: B65D5/36
Filed: 2004-05-13
Abstract: A portable food dispenser (10) includes one or more containers. A first container (11) is capable of being only partially opened to provide access t o food or a second container (14). The second container includes a cover that can be opened to provide access to food.
Patent CA-2525930-A1 (CA)
Inventor: ROACH JOHN
IPC: F17C5/00
Filed: 2004-06-08
Abstract: An installation comprises a vault (4) housing a liquefied storage tank (2), a chamber (14) within the vault (4) accessible to personnel, a liquefied gas inlet pipeline leading to the gas storage tank (2), a liquefied gas supply pipeline (22) extending from the storage tank (2) through a vaporiser (37) out of the vault (4) and at least one first cabinet (34, 36, 38) through which the liquefied gas supply pipeline (22) passes. The first cabinets (34, 36, 38) are located in the chamber and house items of equipment in the liquefied gas supply pipeline (22) which have an associated risk of leakage. There is also at least one first extractor fan communicating with the first cabinets (34, 36, 38) and means separate from the first extractor fan for changing the atmosphere in the chamber.
Patent CA-2526567-A1 (CA)
Title: Oil emulsion for postnatal hormone substitution
Inventor: POHLANDT FRANK
IPC: A61K9/107
Filed: 2004-06-15
Abstract: The invention relates to a method for the production of hormone-containing oil emulsions (lipid emulsions), an isotonic oil emulsion obtainable by said method and the use of said emulsion for the production of a medicament for intravenous administration, in particular, for postnatal hormone substitution in premature babies and for the treatment of neurological damage after cerebral infarction.
Patent CA-2527096-A1 (CA)
Title: Excess lead retaining and management devices and methods of using same
Inventor: SHELLOCK FRANK G
IPC: A61N1/00
Filed: 2004-05-28
Abstract: A device and method for retaining an excess portion of a lead (L) implanted within or on a surface of a brain of a patient is disclosed. The device comprises a burr hole ring (10) configured to be secured to a skull of the patient and a lead retainer (425) extending from the burr hole ring (10). The lead retainer (425) is configured to store at least a section of the excess portion of lead (L).
Patent CA-2528173-A1 (CA)
Title: Cci-779 isomer c
Inventor: MATTES JAMES F
IPC: C07D498/18
Filed: 2004-07-06
Abstract: Purified CCI-779 Isomer C is provided, as are pharmaceutical compositions and kits containing same.
Patent CA-2529935-A1 (CA)
Title: Optical microelectromechanical structure
Inventor: HENNINGSEN HENNING
IPC: B81B7/00
Filed: 2003-06-06
Abstract: The invention relates to an optical microelectromechanical structure (MEMS) comprising - an (at least one) optically transmissive layer (UTL) - an (at least one ) intermediate layer structure (IL) - a (at least one) device laye r (DL) said intermediate layer structure (IL) defining one or more optical pat hs (OP) between said substantially optically transmissive layer (UTL) and said device layer (DL), said intermediate structure layer (IL) defining the distance (d) between said optically transmissive layer (UTL) and said device layer (DL).
Patent CA-2530353-A1 (CA)
Inventor: TSUKIDA TATSUYA
IPC: C09J7/02
Filed: 2004-08-17
Abstract: An adhesive sheet for a tire having excellent adhesiveness also to tires and studless tires at low temperatures and a method of manufacturing the adhesive sheet. The adhesive sheet comprises a base material and an adhesive agent layer. The adhesive agent layer further comprises a hot-melt type adhesive agent composition, and is formed to fulfill the requirements of the adhesive strength characteristics (A) and (B) below. (A) A loop tack adhesive strength at 5~C is 14 N/25 mm or higher. (B) A loop tack adhesive strength at 40~C is 5 N/25 mm or higher.
Patent CA-2532388-A1 (CA)
Title: Coated medical devices and methods of making and using
Inventor: ZHANG ZONGTAO
IPC: A61L27/14
Filed: 2006-01-06
Abstract: A medical device generally includes a structural member having a surface wherein at least a portion of the surface is coated with a nanostructured material to a thickness of at least about 25 micrometers, and wherein the nanostructured material comprises a ceramic, ceramic composite, ceramic metal composite, or a combination comprising at least one of the foregoing.   The implants have increased service lifetimes owing in part to improved wear and abrasion resistance, and may be useful for partial or full replacement of articulating and flexible hinge joints.
Patent CA-2534078-A1 (CA)
Title: Implantable or insertable medical devices containing graft copolymer for controlled delivery of therapeutic agents
Inventor: STRICKLER FREDERICK H
IPC: A61F2/82
Filed: 2004-07-29
Abstract: Implantable or insertable medical devices are described. The medical devices comprise (a) a therapeutic agent and (b) a polymeric release region that controls the release of the therapeutic agent upon administration to a patient. The polymer release region comprises a graft copolymer, which further comprises a main chain and a plurality of side chains. One of (a) the main chain and (b) the side chains corresponds to a rubbery phase within the release region at ambient temperatures, while the other corresponds to a hard phase within the release layer at ambient temperatures. Typically, the graft copolymer will comprise one glass transition temperature below ambient temperature and another second glass transition temperature above ambient temperature. Also described are methods for forming the above graft copolymers, methods for administering a therapeutic agent to a patient using the above implantable or insertable medical devices, as well as methods for making the above devices.
Patent CA-2534222-A1 (CA)
Title: System for optimizing drilling in real time
Inventor: MORAN DAVID P
IPC: E21B44/00
Filed: 2006-01-26
Abstract: A method for optimizing drilling parameters includes obtaining previously acquired data, querying a remote data store for current well data, determining optimized drilling parameters for a next segment,and returning the optimized parameters for the next segment to the remote data store. Determining optimized drilling parameters may include correlating the current well data to the previously acquired data, predicting drilling conditions for the next segment, and optimizing drilling parameters for the next segment.
Patent CA-2536172-A1 (CA)
Title: Flame retardant thermoplastic films and methods of making the same
Inventor: GALLUCCI ROBERT R
IPC: H05K1/00
Filed: 2004-08-12
Abstract: A film can comprise greater than or equal to about 95 wt% thermoplastic resin and about 0.001 wt% to about 5.0 wt% sulfonate salt, based on a total weight of the film, and have a UL-94 rating of VTM-0, wherein the thermoplastic resin is selected from the group consisting of polyimide, polysulfone, and copolymers, reaction products, and combinations comprising at least one of the foregoing thermoplastic resins.
Patent CA-2538329-A1 (CA)
Title: Suture locking device and methods
Inventor: PARASCHAC JOSEPH F
IPC: A61B17/00
Filed: 2004-09-15
Abstract: The present invention relates to devices and methods for securing a pair of suture lengths together or for using a single strand of suture to secure tissue (s) together at an operative site in a patient without necessarily tying a knot. The suture lock device (10) according to the present invention includes a suturing securing device having an outer body member having a lumen extending therethrough, the lumen defining a suture path through the outer body, an inner wedge member (40) axially insertable into the outer body member (20) to secure a portion of a suture between the wedge and the interior surface of the lock member, an outer tube having a proximal end and a distal end, the outer tube carrying the outer body member at the distal end of the outer tube, the outer tube carrying the wedge proximal to the outer body member, and a pusher member slidable within the outer tube to push the wedge into the lock member.
Patent CA-2538485-A1 (CA)
Inventor: WILLIS ANDRE
IPC: H04L1/00
Filed: 2006-03-03
Abstract: Disclosed herein is a method and apparatus used to detect phase error information between edges of an input data signal and a clock signal for use at ultra-high frequencies and where linear phase error information is required.  This invention extends the usefulness of a given integrated circuit logic technology to twice the frequency range of application while maintaining the desired linear phase error measurement operation. Flip flops are used to sample the data input signal with the clocking signal and processing is done separately for rising and falling data edges. Analog recombination of phase error information from both edges is then done in a fashion that is not limited by the integrated circuit speed. This invention overcomes limitations of prior methods in that it operates in data applications, provides linear phase error information at very high phase-error bandwidth and can operate at the same maximum speed as the flip flop and logic process technology will allow by operating on bit cells that are a full 1-bit minimum rather than half-bit cells.
Patent CA-2539651-A1 (CA)
Title: Synthetic lethal screen using rna interference
Inventor: KIM ANNETTE S
IPC: C12N15/85
Filed: 2004-09-22
Abstract: The invention provides a method for identifying one or more genes in a cell of a cell type which interact with, e.g., modulate the effect of, an agent, e.g., a drug. For example, an identified gene may confer resistance or sensitivity to a drug, i.e., reduces or enhances the effect of the drug. The invention also provides STK6 and TPX2 as a gene that exhibits synthetic lethal interactions with KSP encoding a kinesin-like motor protein, and methods and compositions for treatment of diseases, e.g., cancers, by modulating the expression of STK6 or TPX2 gene and/or the activity of STK6 or TPX2 gene product. The invention also provides genes involved in cellular response to DNA damage, and their therapeutic uses.
Patent CA-2540880-A1 (CA)
Title: A method and device for controlling drilling fluid pressure
Inventor: STAVE ROGER
IPC: E21B21/00
Filed: 2004-11-24
Abstract: A method and device for controling drilling fluid pressure during subsea drilling, where drilling fluid is pumped down into a borehole (15) and then flows back to a drilling rig (1) via the lined and/or unlined sections of the borehole (15) and a liner (14), wherein the drilling fluid pressure is controlled by pumping drilling fluid out of the liner (14) at the seabed, and where the liner (14) annulus (30) above the drilling fluid is filled with a riser fluid having a density different from that of the drilling fluid.
Patent CA-2541735-A1 (CA)
Title: Conditioning optical fibers for improved ionizing radiation response
Inventor: SANDERS PAUL E
IPC: C03C25/62
Filed: 2006-04-04
Abstract: Embodiments of the present invention provide various methods to fabricate optical fibers with reduced radiation sensitivity. Optical fibers are treated to one or more secondary or post-processing "conditioning" steps to create and anneal residual defects in the glass for improved radiation insensitivity.
Patent CA-2543574-A1 (CA)
Inventor: LEE JAY
IPC: H04M1/00
Filed: 2006-04-18
Abstract: A digital telephone switch allows transparent switching from a conventi on telephone service to a cable digital telephone service. The switch is connected to the customer premises equipment and to the old and new telephone services. In it s initial state, the switch connects the customer premises equipment to the old telephone service, leaving the new telephone service disconnected. Once a ring is detected on the new telephone service, or another appropriate control signal is received , the switch disconnects the customer premises equipment from the old telephone service a nd connects the customer premises equipment to the new telephone service. One embodiment can switch back and forth between the old and new telephone services to accommodate intercoms and the like.
Patent CA-2544771-A1 (CA)
Title: Taurine-modified acrylic acid-based homopolymers for water treatment
Inventor: BRODT GREGOR
IPC: C02F5/12
Filed: 2004-11-05
Abstract: The invention relates to (meth)acrylic acid copolymers comprising methacrylic acid units. The polymer is functionalised with aminoalkyl sulphonic acids. The invention also relates to a method for the production thereof and to the use thereof for treating water, preventing scale during the extraction of oil, and for preventing corrosion in aqueous systems.
Patent CA-2546146-A1 (CA)
Title: Directing electromagnetic energy from an area or volume source
Inventor: ANDERSON JOHN ERNEST
IPC: G02B5/10
Filed: 2006-05-09
Abstract: An apparatus directs electromagnetic energy, particularly for use in defence as a directed energy weapon, means of illumination for an active sensor and/or guidance system, countermeasure, or to ignite a fusion weapon; power transmission by means of a beam; propulsion by means of a beam or inertial fusion; power generation from inertial fusion; or telecommunications, from a source 3 comprising an area or volume as opposed to a point. Existing apparatus for directing electromagnetic energy from such a source in which all the optical surfaces are reflective and axially symmetric, known as an "eye mirror" , if small, limits the length of the plasma arc, or arcs, within. Figure 1 shows an eye mirror 74 comprising first, second and third stage defining mirrors 30, 32 and 34 respectively and first, second and third stage defined mirrors 31, 33 and 35 respectively.  The first and second stage defined mirrors form a fixed defined unit 75. The source 3 extends outside the aperture described by the leading edge 147 of the first stage defining mirror 30. A pair of defining rays 5 and 6 respectively emanate from different points on or within said extended source 3 and meet at a point of intersection 7 on a further defined mirror 2. Each of said defining rays 5 and 6 is of a defining wavelength .lambda.. Said first defining ray is reflected from said further defined mirror 2 and intersects the fixed defined unit 75 at a respective further point 8 within the circular cone 91 defined by the angular input aperture at that point. Said second defining ray 6 is reflected from said further defined mirror 2 and intersects the fixed defined unit 75 at a respective further point 10 within the circular cone 92 defined by the angular input aperture at that point. There are two such defining rays for every point on the further defined mirror. The further defined mirror 2 lies outside the aperture described by the leading edge 147 of the first stage defining mirror 30 and is axially symmetric about the axis of symmetry 18.
Patent CA-2546683-A1 (CA)
Inventor: KRAFFT PHILIPPE
IPC: C07C31/36
Filed: 2004-11-18
Abstract: Use of glycerol obtained from renewable raw materials, as starting product for producing organic compounds. Process for producing dichloropropanol, according to which glycerol is subjected to a reaction with a chlorinating agent, with the exception of a batch reaction carried out in the presence of acetic acid or its derivatives.
Patent CA-2546848-A1 (CA)
Inventor: TAKEDA JUNJI
IPC: A01K67/027
Filed: 2004-11-19
Abstract: To comprehensively modify genome, it is intended to develop a transposition system of the copy and paste type which has an improved efficiency. This object has been achieved by the finding that an LTR retrotransposon is partly usable in a transposition system. Namely, a technique of efficiently transferring a foreign gene into a cell by using a transposon. More specifically speaking, a complete IPA element and a functional promoter sequence are found out. It is clarified that, without a combination of them, a retrotransposon cannot exert its function.
Patent CA-2547919-A1 (CA)
Title: Viscoelastic surfactant gels with reduced salt concentration
Inventor: TUSTIN GARY JOHN
IPC: C09K8/68
Filed: 2004-10-11
Abstract: A well bore treatment fluid of viscoelastic surfactants and methods for increasing the viscosity of the fluid at high temperature without increasing its salt concentration by adding a organic hydrophilic-lipophilic compound and reducing the salt concentration below 6 per cent.
Patent CA-2548568-A1 (CA)
Inventor: DEVRIES SCOTT
IPC: G06Q40/06
Filed: 2006-05-26
Abstract: The present invention relates to analyzing and reporting of data and information, and particularly to analyzing and reporting of financial and investment data and information. More specifically, the present invention provides a method for the reporting of financial data comprising the steps of receiving first data from a first data source which contains data relating to a least one investment, receiving second data from a second data source which contains data relating to at least one client transaction relating to the at least one investment, calculating at least one element of financial data utilizing first data and second data, and reporting the calculated financial data. In this manner, investors, and their advisers, can be provided with timely information and analysis in relation to the investor's overall investment position and portfolio statistics.
Patent CA-2552954-A1 (CA)
Title: Use of an extract of pueraria tuberosa for the treatment of diabetes type 2
Inventor: MANDAL SWAPAN KUMAR
IPC: A61K36/488
Filed: 2004-12-27
Abstract: The present invention relates to a method of preventing and/or treating diabetes type 2, also, it relates to a method of augmenting Glut4 phosphorylation and Glut4 translocation to a target cell membrane to enhance insulin signal in a signal transduction pathway; further, it relates to a simplified and inexpensive process of obtaining extract and thereafter selectively, its active n-butanol fraction and active molecule Lupinoside PA  (LPA4), useful in preventing and/or treating diabetes type 2; and lastly, a pharmaceutical composition thereof.
Patent CA-2554363-A1 (CA)
Inventor: LIN TINA
IPC: B25H3/02
Filed: 2006-07-27
Abstract: A device for receiving tools comprises a base and at least one bracket for receiving at least one tool, wherein the bracket is mounted on the base pivotally and can be pivotally rotated between a receiving position and an access position. Further, the bracket includes at Least one receiving recess which can receive the tool, and the base is formed with at least one taking recess, near the access position near the bracket. When the bracket is pivoted to the access position, the receiving recess and the taking recess are aligned approximately, and the tool received in the bracket is allowed to move longitudinally so as to be taken easily.