baber/WOPTO huggingface dataset:
Patent NZ-583790-A (NZ)
Title: Process for the preparation the raf kinase inhibitor sorafenib and intermediates for use in the process
Inventor: RAO DHARMARAJ RAMACHANDRA
IPC: C07C275/64
Filed: 2008-09-10
Abstract: A process for the preparation of the raf kinase inhibitor sorafenib using a compound of formula (A) wherein R' is selected from -C(O)OA, -C(O)CX3, C(O)NH2, -C(O)-NHON or (a). The process comprises the condensation reaction of the compounds of formula (A) with 4-(4-aminophenoxy)-N-methylpicolinamide, or when R' is (a) the reaction with 4-chloro-N-methyl-2-pyridine in the presence of a base.
Patent NZ-584533-A (NZ)
Title: Reflector for positioning over an array of leds or other light sources
Inventor: BOYER JOHN D
IPC: F21V7/10
Filed: 2008-10-21
Abstract: A sheet metal reflector device is disclosed for positioning in a spaced relation to a light source assembly with a plurality of light sources. The reflector device comprises a base (12) having a plurality of first openings (27) defined by an annular rim (25) and a plurality of reflector elements (20), each reflector element corresponding to one of the light sources. The reflector elements (20) extend from a corresponding annular rim (25) and include an annular sidewall (22) with an inner reflective surface (23). The inner reflective surface (23) extends from the corresponding annular rim (25) of the base to a corresponding distal annular rim (29) that defines a second opening (37) capable of accommodating an associated light source. The base (12) separates each first opening (27) from each other first opening (27). The plurality of reflector elements (20) are formed by depressing a planar sheet of material. A luminaire comprising such a reflector device and a method making such a device are also disclosed.
Patent NZ-586479-A (NZ)
Title: Tunnel dressing for treating a wound with suction including a permeable inner layer which resists compression
Inventor: RADL CHRISTOPHER L
IPC: A61F13/36
Filed: 2007-12-31
Abstract: Disclosed is a tunnel dressing (10) for use in treating a tunneling wound using negative pressure wound therapy. The tunnel dressing includes an elongate permeable member having a closed distal end (46) for entering the wound and an open proximal end (48) into which a removeable applicator is disposed for guiding the dressing into the wound. The tunnel dressing has a support structure (14) adapted to transport wound exudates away from the wound and to resist compression under suction. The tunnel dressing also has a wound contact surface (20) adapted to minimize tissue entanglement to facilitate removal. The support structure and wound contact surface may be formed from the same material or from two adjacent layers of different material.
Patent NZ-589486-A (NZ)
Title: A process for the preparation of enantiomerically pure 1-(R)-(2-propynylamino)indan
Inventor: GORE VINAYAK
IPC: C07C211/42
Filed: 2009-06-02
Abstract: A process for the preparation of enantiomerically pure (R)-1-aminoindan (2) is disclosed, which comprises the formation of a diastereomeric salt of 1-aminoindan with 2,3,4,6-di-O-isopropylidene-2-keto-L-gulonic acid, wherein the salt formation preferably takes place in an organic solvent or a mixture of an organic solvent and water, and wherein the organic solvent may be selected from the group comprising methanol, ethanol, n-propanol, isopropanol, n-butanol, isobutanol, tert-butanol and mixtures thereof. The disclosure also relates to the conversion of (R)-1-aminoindan (2) formed to rasagiline (1) or a pharmaceutically acceptable salt thereof, preferably rasagiline mesylate salt.
Patent NZ-590466-A (NZ)
Title: Treatment of inflammatory diseases with mammal beta defensins
Inventor: KJAER TANJA MARIA ROSENKILDE
IPC: A61K38/17
Filed: 2009-07-17
Abstract: Use of a human beta defensin having at least 80% identity to the amino acid sequences of SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3 or SEQ ID NO:4 in the manufacture of a medicament for the treatment of an inflammatory disease or disorder selected from the group consisting of osteoarthritis, multiple sclerosis, artherosclerosis, scleroderma (systemic sclerosis), lupus, systemic lupus erythematosus (SLE), (acute) glomerulonephritis, asthma, chronic obstructive pulmonary diseases (COPD), respiratory distress-syndrome (ARDS), vasculitis, uveitis, dermatitis, atopic dermatitis, alopecia, rhinitis (allergica), allergic conjunctivitis, myasthenia gravis, sclerodermitis, sarcoidosis, psoriatic arthritis, psoriasis, ankylosing spondylitis, juvenile idiopathic arthritis,Graves disease, Sjogren's syndrome, and Behçet disease.
Patent NZ-590988-A (NZ)
Title: Biomarkers for anti-tnf treatment in ulcerative colitis and related disorders
Inventor: LI KATHERINE
IPC: C12Q1/68
Filed: 2009-08-19
Abstract: Disclosed is a method for predicting the suitability of treatment with anti-TNF therapy for an inflammatory gastrointestinal disorder in a subject, comprising: a) preparing a sample of nucleic acids from a specimen obtained from the subject; and b) assaying said sample with a panel of labeled nucleic acid segments that hybridize to BCL6, Genbank Acc. No. A W264036; SEQ ID NO:118 and tx82a04.xl, Genbank Acc. No. AI689210; SEQ ID NO:123, wherein down regulation of said genes correlates with therapeutic efficacy for the treatment of an inflammatory gastrointestinal disorder. Further disclosed is an array-based testing method for predicting the suitability of treatment with an anti-TNF therapy for an inflammatory gastrointestinal disorder in a patient, comprising: c) preparing a mixture of nucleic acids from a specimen obtained from the patient for use in a micro array based assay; d) assaying said sample with a panel of labelled nucleic acid probes that hybridize to BCL6, Genbank Acc. No. AW264036; SEQ ID NO: 118 and tx82a04.x1, Genbank Acc. No. AI689210; SEQ ID NO:123, using a micro array-based assay, wherein said probes comprise SEQ ID NO: 37, and SEQ ID NO: 41, wherein down regulation of said genes correlates with therapeutic efficacy for the treatment of an inflammatory gastrointestinal disorder.
Patent NZ-595434-A (NZ)
Title: Antibacterial composition comprising 4 -isopropyl-3-methylphenol and zinc ions
Inventor: AXE ALISON
IPC: A61K8/27
Filed: 2010-04-01
Abstract: Abstract 595434 The disclosure relates to a composition such as an oral care composition such as a tothpaste or mouthwash comprising an antibacterial system comprising 4-isopropyl-3 -methyl phenol (IPMP), a source of zinc ions and an alkali metal C8-18alkyl sulphate or an alkali metal C8-18alkylaryl sulphonate, such as sodium lauryl sulphate and sodium dodecylbenzene sulphonate, or a mixture thereof and an orally acceptable carrier or excipient.
Patent NZ-597972-A (NZ)
Title: Natural and sustainable seaweed formula that replaces synthetic additives in fish feed containing ulva lactuca and ascophyllum nodosum
Inventor: KRAAN STEFAN
IPC: A23K1/18
Filed: 2010-07-16
Abstract: Patent No. 597972 Disclosed is an additive for use in feed for fish and other marine animals containing between about 40-75% by weight of Ulva lactuca ("Ulva") and between about 5-7.0% by weight of Ascophyllum nodosum ("Asco").
Patent NZ-599463-A (NZ)
Title: Process for making ethanol from acetic acid using acidic catalysts
Inventor: JEVTIC RADMILA
IPC: B01J21/04
Filed: 2010-10-26
Abstract: Disclosed herein is a process for selective formation of ethanol from acetic acid by hydrogenating acetic acid in the presence of a catalyst comprises a first metal on an acidic support. The acidic support may comprise an acidic support material or may comprise an support having an acidic support modifier. The catalyst may be used alone to produced ethanol via hydrogenation or in combination with another catalyst. In addition, the crude ethanol product is separated to obtain ethanol. In one embodiment the process comprises hydrogenating acetic acid in the presence of a first catalyst comprising one or more metals, a silicaceous support and at least one basic support modifier, to form ethanol and unreacted acetic acid; and hydrogenating the unreacted acetic acid in the presence of a second catalyst comprising a first metal on an acid support comprising iron oxide, alumina, silica/alumina, titania, zirconia, mixtures thereof, or a support material modified with an acidic modifier.
Patent NZ-616180-A (NZ)
Title: Otamixaban formulations with improved stability
Inventor: KAMM WALTER
IPC: A61P7/02
Filed: 2012-03-27
Abstract: Disclosed is a pharmaceutical composition comprising methyl (2R,3R)-2-{ 3-[amino(imino)methyl]benzyl} -3-{ [4-(1-oxidopyridin-4-yl)benzoyl]amino} butanoate of formula (I) (Otamixaban) or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable acidic reacting compound such as citric acid, tartaric acid, succinic acid, malic acid, or phosphoric acid. The pharmaceutical compositions have improved stability and long term storage. Also disclosed are methods of using such compositions to treat subjects suffering from conditions which can be ameliorated by the administration of an inhibitor of Factor Xa.
Patent NZ-618269-A (NZ)
Title: Application notifications
Inventor: DONAHUE TYLER J
IPC: G06F3/14
Filed: 2011-10-09
Abstract: Disclosed is a method implemented by one or more computing devices for displaying a notification of an application. The method comprises displays a representation of an application in a user interface (200) and receives one or more notifications that pertain to the application to be displayed as part of the representation of the application in the user interface (200). Then examines a manifest of the application without executing the application to find criteria specifying how and when the notifications are to be displayed as part of the representation of the application in the user interface (200). Finally, displays the representation of the application as including the one or more notifications in the user interface (200) according to the specified criteria.
Patent NZ-618372-A (NZ)
Title: Amide compound and pharmaceutical application therefor
Inventor: MAEBA TAKAKI
IPC: C07D413/06
Filed: 2012-04-27
Abstract: Disclosed herein is a compound of formula [I-W] and pharmaceutical compositions thereof which can inhibit retinoid-related orphan receptor gamma (RORγ), thereby the differentiation and activation of T helper L7 (Thl-7) cells can be inhibited, and the production of interleukin-17 (IL-l7) can be inhibited. This is useful for preventing or treating a disease related to Th17 cells, for example, an autoimmune disease. In one embodiment tert-butyl 4-(2-chloro-4-methylphenylcarbamoyl)-3-{ 4-cyclopropyl-5-[3-(Z-ethylbutyl)cyclobutyl]isoxazol-3-yl)butanoate.
Patent NZ-618944-A (NZ)
Title: Crystal of fused heterocyclic compound
Inventor: YAMAMOTO KATSUHIKO
IPC: C07D471/04
Filed: 2012-06-21
Abstract: Disclosed herein is a crystal of 1-ethyl-7-methyl-3-{ 4-[(3-methyl-3H-imidazo[4,5-b]pyridin-2-yl)oxy]phenyl} -1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one which is thermodynamically, chemically and physically stable. The crystal shows an X-ray powder diffraction pattern having characteristic peaks at interplaner spacings (d) of 13.59 ± 0.2, 6.76 ± 0.2, 9.22 ± 0.2, 7.88 ± 0.2, 6.21 ± 0.2, 6.13 ± 0.2, 5.73 ± 0.2, 4.64 ± 0.2, 3.79 ± 0.2 and 3.75 ± 0.2 Angstroms in powder X-ray diffraction. The crystal also shows an initial temperature of 222-224 °C of an endothermic behaviour caused by melting in DSC measurement (temperature increase rate 5 °C/min). The crystal is a phosphodiesterase 10A (PDE10A) inhibitor useful in the treatment of schizophrenia.
Patent NZ-619818-A (NZ)
Title: Method of producing an alcoholic beverage having a fruity flavor
Inventor: DORSEY AUDREY JOYCE
IPC: C12P11/00
Filed: 2012-07-31
Abstract: The disclosure relates to a method of producing an alcoholic beverage by fermentation having flavor and taste of passion fruit and grapefruit, characterized in that it comprises the following steps: providing a gas stream containing hydrogen sulfide, bubbling the gas stream containing hydrogen sulfide into a grape juice and/or grape juice derived fractions prior to yeast inoculation, and/or during fermentation. The alcoholic beverage obtainable by the method can be chosen from the group constituted by wines, beers and spirits. Most preferably, the alcoholic beverage is a Sauvignon Blanc wine.
Patent NZ-703943-A (NZ)
Title: Wind turbine rotary electric machine rotor and wind turbine comprising such a rotor
Inventor: CASAZZA MATTEO
IPC: H02K7/18
Filed: 2013-07-25
Abstract: A rotor (9) of a wind turbine rotary electric machine (4) has a tubular structure (12) extending and designed to rotate about an axis of rotation (A); a plurality of active segments (15) parallel to and arranged about the axis of rotation (A) and fitted to the tubular structure (12); and a plurality of cooling channels (22) formed in the tubular structure (12).
Patent NZ-721036-A (NZ)
Title: Lipid comprising long chain polyunsaturated fatty acids
Inventor: PETRIE JAMES ROBERTSON
IPC: A01H5/00
Filed: 2014-12-18
Abstract: The present invention relates to extracted Brassica napus plant lipid comprising docosahexaenoic acid (DHA) wherein the level of DHA in the total fatty acid content of the extracted lipid is between 20.1% and 30% or between 20.1% and 35% and wherein at least 70% of the DHA esterified in the form of TAG is in the sn-1 or sn-3 position of the TAG.
Patent NZ-723063-A (NZ)
Title: Real-time detection of periodic breathing
Inventor: RAMANAN DINESH
IPC: G16H40/63
Filed: 2015-02-13
Abstract: A method for a device detects periodic breathing in a patient. The method may include receiving a series of event intervals bounded by apnea or hypopnea events detected in respiration of the patient, and processing, upon closure of an event interval, the event interval to determine a character of the event interval, such as any of: probably a periodic breathing cycle; probably not a periodic breathing cycle; and uninformative. The method may further include determining whether to change a current periodic breathing state that indicates whether a periodic breathing episode is in progress, based on a history of event interval characters that is long compared to the typical length of a periodic breathing cycle.
Patent NZ-724002-A (NZ)
Title: Liquid formulation comprising propylene glycol and an ace inhibitor
Inventor: BOVA NICHOLAS
IPC: A61P9/10
Filed: 2013-05-17
Abstract: The invention relates to a liquid formulation comprising propylene glycol and an effective amount of an inodilator, an angiotensin converting enzyme inhibitor, or a combination of an inodilator and an angiotensin converting enzyme inhibitor and to use of the formulation for treating cardiac disease and/or hypertension.
Patent NZ-740686-A (NZ)
Title: Therapeutic cd47 antibodies
Inventor: MANNING PAMELA
IPC: A61K39/00
Filed: 2016-09-17
Abstract: Provided are anti-CD47 monoclonal antibodies (anti-CD47 mAbs) with distinct functional profiles as described herein, methods to generate anti-CD47 mAbs, and to methods of using these anti-CD47 mAbs as therapeutics for the prevention and treatment of solid and hematological cancers, ischemia-reperfusion injury, cardiovascular diseases, autoimmune diseases, inflammatory diseases or as diagnostics for determining the level of CD47 in tissue samples. In a particular embodiment, the anti-CD47 mAbs comprise the heavy chain CDRs GYTFTNYWIH (CDR1), YTDPRTDYTEYNQKFKD, YTDPRTDYTEYAQKFQG or YTDPRTDYTEYSPSFQG (CDR2), and GGRVGLGY (CDR3) and the light chain CDRs RSSQNIVQSNGNTYLE (CDR1), KVFHRFS (CDR2), and FQGSHVPYT (CDR3), wherein these particular embodiments bind to human CD47 on tumor cells, but not red blood cells.
Patent NZ-750319-A (NZ)
Title: Method for separating cell from biological tissue
Inventor: GOTO MASAFUMI
IPC: C12N1/00
Filed: 2014-01-31
Abstract: Provided is a cell separation method, whereby liver cells having a high biological activity can be efficiently and stably separated from a liver tissue, characterized by comprising using a degrading enzyme composition that is prepared by adding, to a definite amount of a neutral protease and/or a protease derived from Clostridium sp.,an amount of collagenase H and collagenase G capable of degrading a major protein in the biological tissue, the amount of said degrading enzyme being determined depending on the composition of collagen I and or collagen III in the biological tissue. According to this method, the kind and amount of a protein-degrading enzyme to be used for isolating liver cells from a liver tissue can be determined on the basis of the composition of collagen I and or collagen III in the liver tissue. Thus, the amount of collagenase H and collagenase G protein-degrading enzyme to be used can be controlled and liver cells having a high biological activity can be efficiently separated.
Patent NZ-756435-A (NZ)
Title: Chitosan and polyethylene glycol copolymers and methods and devices for using same for sealing a vascular puncture
Inventor: MYLONAKIS ANDREAS
IPC: A61L31/06
Filed: 2015-05-28
Abstract: A sealant is provided for sealing a puncture through tissue that comprises an elongate first section including a proximal end, a distal end, and a cross-section sized for delivery into a puncture through tissue, and a second section extending from the distal end of the first section. The first section may be formed from a freeze-dried hydrogel that expands when exposed to physiological fluid within a puncture. The first section comprises chitosan and at least one additional polymer. The second section may be formed from a solid mass of non-freeze-dried, non-cross-linked hydrogel precursors. The precursors are in an unreactive state until exposed to an aqueous physiological environment, whereupon the precursors undergo in-situ crosslinking with one another to provide an adhesive layer bonded to the first section. The second section may further comprise chitosan. Apparatus and methods for delivering the sealant into a puncture through tissue are also provided.
Patent NZ-757832-A (NZ)
Title: Satellite attitude control system using eigen vector, non-linear dynamic inversion, and feedforward control
Inventor: John Benton derrick II
IPC: B64G1/24
Filed: 2019-10-03
Abstract: Systems and methods are described for a satellite control system that exhibits improved stability and increased efficiency by implementing a non-linear dynamic inversion inner-loop control algorithm coupled with an eigen vector outer-loop control algorithm. Thus, the attitude determination and control system (ADACS) may operate using commands to rotate directly about an eigen vector. Additionally, the outer-loop control system includes a feed-forward control element to enhance pointing accuracy when tracking moving targets.
Patent NZ-770580-A (NZ)
Title: A method of controlling a self-retracting lifeline
Inventor: ALLINGTON CHRISTOPHER JAMES
IPC: F16D27/01
Filed: 2014-12-04
Abstract: Described herein is a method of controlling a Self Retracting Lifeline (SRL) apparatus. The method uses a self-retracting lifeline comprising a coupler configured to selectively couple a spool having a line thereon to a latch on an external member, and in doing so slow or halt relative motion between the spool and the external member. The method comprises applying a force to the line causing withdrawal of the line from the spool; and when the spool rotates, due to line withdrawal from the spool, below a velocity and acceleration threshold, the pawl oscillates radially outward and inward relative to an axis of rotation of the spool and the coupler does not couple the spool to the external member; and when the spool rotates, due to line withdrawal from the spool, above the velocity and acceleration threshold, the pawl moves radially outward to a deployed position such that the pawl or a part thereof engages the latch, thereby coupling the external member to the spool and in doing so halting relative motion between the external member and the spool. The problem to be solved is the the lack of movement control and the solution provided is an improved dynamic response.
Patent NZ-778846-A (NZ)
Title: Dome cover
Inventor: HARLOFF OLIVER
IPC: B65D90/10
Filed: 2019-08-08
Abstract: The present invention relates to a dome cover assembly for automatically opening and closing a through-opening. The problem addressed by the present invention is that of providing a dome cover assembly, the dome cover ensuring that opening of the dome cover is prevented when there is pressure in the tank, and the dome cover assembly in particular not requiring any extension into the tank. Said problem is solved by means of a dome cover assembly, which comprises, on at least one first element from among the cover and the flange, at least one reach-around element, the at least one reach-around element of the cover and/or the at least one reach-around element of the flange being designed in each case to at least partially enclose, in the first rotational position, the other element from among the cover and the flange, on which said at least one reach-around element is not arranged, on the side facing away from the first element. The other element from among the cover and the flange has a recess toward the first element on the side facing away from the first element, the at least one reach-around element and the recess being designed and arranged in such a way that, in the first rotational position, the reach-around element engages behind the recess in a first distanced position of the cover and the flange and in such a way that, in the first rotational position, the reach-around element does not engage behind the recess in a second closer position of the cover and the flange.
Patent PT-103411-A (PT)
Title: Processo de legendagem integrada para pessoas com surdez
Inventor: SANTOS JOSE NEVES JOSELIA MARIA
IPC: G10L21/00
Filed: 2005-12-30
Abstract: A PRESENTE INVENÇ&O DIZ RESPEITO A UM PROCESSO DE LEGENDAGEM PARA A APRESENTAÇÃO VISUAL E TÁCTIL DA COMPONENTE SONORA (DISCURSO - EFEITOS SONOROS - MÚSICA) DE PRODUTOS AUDIOVISUAIS (TELEVISÃO - VÍDEO/DVD - CINEMA - TEATRO - ÓPERA - CONFERÊNCIAS - MATERIAIS MULTIMÉDIA) PARA ALÉM DE APRESENTAR O DISCURSO EM LEGENDAS CONCEBIDAS COM CUIDADOS ESPECIAIS PARA A INCREMENTAÇÃO DA VELOCIDADE DE LEITURA, INTEGRA INFORMAÇÃO PARALINGUÍSTICA E NÃO- VERBAL ATRAVÉS DE ICONES E OUTRAS ESTRATÉGIAS DE VISUALIZAÇÃO CODIFICADAS, TAIS COMO O USO DE CORES, A DIVERSIFICAÇÃO DE FONTES, O POSICIONAMENTO NO ECRÁ E PROCESSOS DE VISUALIZAÇÃO E PERCEPÇÃO TÁCTIL DE EFEITOS SONOROS E MÚSICA. OS DIFERENTES COMPONENTES SÃO INTEGRÁVEIS DE FORMA SELECTIVA E/OU CUMULATIVA PERMITINDO QUE O MESMO PRODUTO AUDIOVISUAL SE ADAPTE ÀS NECESSIDADES ESPECÍFICAS DE DIFERENTES RECEPTORES.
Patent RU-94009802-A (RU)
Inventor: JAKHIN I A
IPC: C12P1/04
Filed: 1994-03-22
Abstract: FIELD: agriculture, in particular, presowing seed treatment and treatment of vegetative plants. SUBSTANCE: preparation is made as balanced system of physiologically active metabolic substances obtained from plants and made in the form of powder. Presowing crop seed treatment is effectuated by all-purpose seed dressing machines, with preparation consumption rate being 0.4 g per 1 ton of seeds in 8-12 l of water to obtain final concentration of solution of 0.003%. When used for treatment of vegetative plants, preparation dose is 9 g/ha in 300 l of water, with final concentration of solution being 0.003%. Plants are sprayed by aqueous solution of preparation at tillering-initial shooting stage. EFFECT: high stimulating and fungicidal effect and increased crop yield.
Patent RU-94016148-A (RU)
Inventor: NOVIKOVA N I
IPC: A61F6/14
Filed: 1994-05-04
Abstract: FIELD: medical appliances. SUBSTANCE: this solves problem of reducing harmful effect on internal walls of uterus when using endouterus contraceptives. Offered is endouterus contraceptive having rod with copper spiral and flexible horizontal branches in the form of shoulders and slipped over them are copper bushes. Shoulders have taper-shaped protrusions with their maximal diameter equal to diameter of bush. EFFECT: high efficiency. 1 dwg