baber/WOPTO huggingface dataset:
Patent WO-2021263173-A1 (WO)
Inventor: REN SHUNLIN
IPC: A61K31/575
Filed: 2021-06-25
Abstract: Aspects of the present disclosure include methods for treating at least one of depression, neurodegenerative disease, multiple sclerosis, Parkinson's disease, spinocerebellar degeneration, Friedreich ataxia, ataxia-telangiectasia, progressive supranuclear palsy, Huntington's disease, striatonigral degeneration, olivopontocerebellar atrophy, Shy-Drager syndrome, schizophrenia, schizoaffective disorder, manic-depression (bipolar) disorder, disturbed or abnormal circadian entrainment, childhood Alice in Wonderland syndrome, childhood acute cerebellar ataxia, and Alzheimer's disease. In some instances, methods include treating an addiction to a drug, such as alcohol addiction, cocaine addiction or amphetamine addiction. In practicing the subject methods, an effective amount of at least one compound selected from 25-hydroxycholesterol-3-sulfate (25HC3S), 25-hydroxycholesterol-disulfate (25HCDS), 27-hydroxycholesterol-3-sulfate (27HC3S), 27-hydroxycholesterol-disulfate (27HCDS), 24-hydroxycholesterol-3-sulfate (24HC3S), 24-hydroxycholesterol-disulfate (24HCDS), and 24,25-epoxycholesterol-3-sulfate, or salt thereof is administered to the subject.
Patent WO-2022011314-A1 (WO)
Inventor: GANDLA DEEPA
IPC: A61P25/28
Filed: 2021-07-09
Abstract: L'invention concerne des formes cristallines d'un agoniste GABA A  α5, des compositions pharmaceutiques et des combinaisons comprenant ces formes cristallines, leur utilisation dans des procédés de traitement d'une déficience cognitive associée aux troubles du système nerveux central (SNC), d'une déficience cognitive associée au cancer du cerveau, du cancer du cerveau lui-même ou de la psychose de la maladie de Parkinson, ainsi que des procédés de production des formes cristallines.
Patent WO-2022098402-A1 (WO)
Inventor: SIMON ANDREAS
IPC: B66F17/00
Filed: 2021-07-20
Abstract: L'invention concerne un procédé de fonctionnement d'un véhicule de manipulation de matériaux (10) comprenant : la surveillance, par un processeur (103), de l'accélération du véhicule dans une direction de déplacement du véhicule pendant une opération manuelle par un opérateur du véhicule lorsque le véhicule se déplace dans une première orientation de véhicule; la collecte et le stockage, par le processeur, de données relatives à l'accélération de véhicule surveillée; la réception, par le processeur, d'une demande de mise en œuvre d'une opération de conduite semi-automatisée; le calcul, par le processeur, d'une accélération maximale du véhicule sur la base de données d'accélération comprenant les données stockées, les données relatives à l'accélération de véhicule surveillée utilisées pour calculer l'accélération de véhicule maximale ne comprenant que les données d'accélération de véhicule dans la direction de déplacement du véhicule collectées lorsque le véhicule se déplace dans la première orientation de véhicule. Sur la base, au moins en partie, de l'accélération maximale du véhicule, le procédé comprend la commande, par le processeur, de la mise en œuvre de l'opération de conduite semi-automatisée.
Patent WO-2022035743-A1 (WO)
Inventor: J HENDERSON MARK
IPC: G01N33/58
Filed: 2021-08-09
Abstract: The disclosure provides methods for carrying out Real Time Cellular Thermal Shift Assays (RT-CETSA). Also provided are molecular constructs and protein constructs for use in such assays and devices suitable for carrying out such assays.
Patent WO-2022035977-A1 (WO)
Title: Dynamically altering an external geometry of body- wearable actuatable components
Inventor: MARCUS BETH A
IPC: A61H3/00
Filed: 2021-08-11
Abstract: Aspects described herein include a method comprising receiving one or more sensor signals from one or more sensors that are worn by a wearer, and determining, based on the one or more sensor signals, one or more poses of a leg of the wearer during motion. The method further comprises controlling, based on the one or more poses, a pressure of one or more actuatable components to adjust the leg toward a target pose during the motion. The one or more actuatable components are worn on one or both of the leg and a foot of the wearer.
Patent WO-2022046791-A1 (WO)
Inventor: LAULICHT BRYAN
IPC: H01M50/119
Filed: 2021-08-24
Abstract: La présente divulgation concerne des piles qui présentent un risque réduit ou un risque nul de lésion œsophagienne ou gastro-intestinale dans un environnement aqueux conducteur, par exemple lorsqu'elles sont accidentellement avalées. Selon certains modes de réalisation, les piles sont des éléments de type piles boutons ou piles à pièces nominalement de 9V, 3V ou 1,5V.
Patent WO-2022066343-A1 (WO)
Title: End effector assembly with thermal cutting element
Inventor: ALLEN IV JAMES D
IPC: A61B18/08
Filed: 2021-08-25
Abstract: An end effector assembly for an electrosurgical instrument includes a pair of opposing jaw members each having a jaw housing supporting an electrically conductive tissue engaging surface thereon. The tissue engaging surfaces are disposed in opposition relative to one another and one or both of the jaw members are movable relative to one another to grasp tissue therebetween. First, second and third thermal cutting elements are disposed on one or both of the tissue engaging surfaces. Each thermal cutting element is independently activatable (or activatable in pairs) relative to the tissue engaging surfaces and each thermal cutting element connects to an electrosurgical energy source. The first thermal cutting element is exposed along the length of the tissue engaging surface, the second thermal cutting element surrounds the distal tip of the jaw member and the third thermal cutting element is disposed on the back of the jaw housing.
Patent WO-2022051671-A1 (WO)
Inventor: KENNEDY JOHN WAYNE
IPC: C08G18/48
Filed: 2021-09-03
Abstract: The disclosure provides compositions and formulations for the treatment and mitigation disease as well as the restoration of cells to a state of metabolic homeostasis. The disclosure further provides exemplary methods of administering a therapeutically effective amount of a composition or formulation comprising a mineral cation complex and ionic salt to a subject for the treatment of disease or disorder. The disclosure further provides exemplary methods of administering a therapeutically effective amount of a composition or formulation comprising a mineral cation complex and ionic salt to a subject for the maintenance or restoration of cellular metabolic homeostasis.
Patent WO-2022076673-A1 (WO)
Inventor: LAKEY JONATHAN
IPC: C12N5/0735
Filed: 2021-10-07
Abstract: L'invention divulgue une microcapsule hybride comprenant : une enveloppe qui comporte au moins un matériau biocompatible, des exosomes contenus dans la microcapsule et au moins une cellule thérapeutique encapsulée à l'intérieur de la microcapsule, les cellules thérapeutiques étant capables de libérer un ou plusieurs agent(s) thérapeutique(s). L'invention divulgue également des procédés de fabrication de la microcapsule hybride et des méthodes de traitement d'un sujet consistant à administrer la microcapsule hybride au sujet, les cellules thérapeutiques contenues dans la microcapsule hybride libérant l'un ou plusieurs agent(s) thérapeutique(s) dans le sujet et la microcapsule hybride libérant les exosomes pour atténuer efficacement une réponse d'origine immunitaire à un corps étranger (FBR).
Patent WO-2022094027-A1 (WO)
Title: Connecteurs de fibres optiques femelles à culbuteur de verrouillage et leurs procédés de fabrication
Inventor: CAPPANNARI STEPHEN PAUL
IPC: G02B6/38
Filed: 2021-10-28
Abstract: La divulgation concerne des connecteurs de fibres optiques femelles ayant une ouverture de port de connexion permettant de recevoir une fiche de fibre optique et des ensembles de câbles comprenant le connecteur de fibre optique femelle conjointement avec leurs procédés de fabrication. Les connecteurs de fibres optiques femelles comprennent un actionneur tel qu'un culbuteur de verrouillage utilisé pour libérer ou fixer une fiche de fibre optique externe qui peut être reçue dans le port de connexion. Un corps principal du connecteur de fibre optique femelle comprend un port de connexion approprié pour recevoir un connecteur de fiche de fibre optique externe. Les connecteurs de fibres optiques femelles divulgués permettent avantageusement une connexion rapide et facile à un connecteur de fiche de fibre optique externe pour des applications renforcées ou d'autres applications souhaitées. Des procédés de terminaison des fibres optiques d'un câble au niveau du connecteur de fibre optique femelle pour former des ensembles de câbles sont également divulgués.
Patent WO-2022104119-A1 (WO)
Title: Code-shield label
Inventor: MILLER TOM
IPC: G09F3/02
Filed: 2021-11-12
Abstract: A label including a first strip including a first end and a second end opposite the first end. The first strip includes an opaque material. The first strip further includes a first area proximate the first end. The first area includes a first length along a longitudinal axis common to the first strip. The label also includes a second strip including a third end and a fourth end opposite the third end, wherein the second strip includes a transparent material. The second strip is laminated over the first strip such that the third end is disposed outside the first area. The fourth end extends beyond the second end a distance at least equal to the first length.
Patent WO-2022132404-A1 (WO)
Title: Automated on-screen windows arrangements
Inventor: PAPAMARCOS ERIC ALEXANDER
IPC: G06F3/14
Filed: 2021-11-23
Abstract: A system for generating windows arrangements for a display is disclosed, which includes a processor and a computer-readable medium storing instructions for controlling the system to perform receiving a first user input requesting to generate windows arrangements for a display; in response to receiving the first user input, identifying, based on contextual information with respect to applications, a group of the applications to be included in the windows arrangements for the display; generating, based on display information of the display and the contextual information with respect to the applications, the windows arrangements, each windows arrangement providing a different on-screen arrangement of a plurality of windows associated with two or more applications of the group and defining a size and position of each of the windows on the display; and displaying a selectable list of the windows arrangements for the display.
Patent WO-2022119992-A1 (WO)
Inventor: ANG KENNETH SHUN QIANG
IPC: G06Q30/06
Filed: 2021-12-02
Abstract: Virtually immersive and physical digital systems and methods are described for dispensing physical consumer products. In various aspects, such systems and methods comprise receiving, by one or more processors from an input controller of a pedestal, a first selection corresponding to a selected virtual product selected from one or more virtual rendered products as rendered on a virtually immersive GUI. Based on the first selection, first virtual immersive graphical content, comprising image frame(s) depicting the selected virtual product, is rendered on a display screen. A second selection corresponding to the selected virtual product is received from the input controller causing second virtual immersive graphical content to be rendered the display screen. The second virtual immersive graphical content comprises image frame(s) depicting the selected virtual product being virtually dispensed or provided. A physical dispenser dispenses a physical product corresponding to the selected virtual product in a location accessible to the user.
Patent WO-2022125882-A1 (WO)
Inventor: OGBURN MICHAEL
IPC: A61K31/352
Filed: 2021-12-10
Abstract: L'invention concerne des compositions pharmaceutiques ou de complément alimentaire, des kits comprenant les compositions pharmaceutiques ou de complément alimentaire, des méthodes de traitement et de prévention d'une maladie, et des procédés de préparation des compositions et de kits décrits dans la description. Les compositions pharmaceutiques ou de complément alimentaire décrites dans la description peuvent être administrées par voie orale. Les compositions pharmaceutiques ou de complément alimentaire peuvent être administrées au moyen d'une capsule décrite dans la description.
Patent WO-2022265671-A1 (WO)
Title: Determining and utilizing secondary language proficiency measure
Inventor: KOGAN DAVID
IPC: G06F40/00
Filed: 2021-12-15
Abstract: Implementations relate to determining a secondary language proficiency measure, for a user in a secondary language (i.e., a language other than a primary language specified for the user), where determining the secondary language proficiency measure is based on past interactions of the user that are related to the secondary language. Those implementations further relate to utilizing the determined secondary language proficiency measure to increase efficiency of user interaction(s), such as interaction(s) with a language learning application and/or an automated assistant. Some of those implementations utilize the secondary language proficiency measure in automatically setting value(s), biasing automatic speech recognition, and/or determining how to render natural language output.
Patent WO-2022140348-A1 (WO)
Title: Oxyanionic templates for surface replication
Inventor: BISHOP MATTHEW
IPC: C23C16/06
Filed: 2021-12-21
Abstract: A method of synthesizing a perimorphic framework by chemical vapor deposition of a perimorph around an oxyanionic template, followed by dissolution of the oxyanionic template in water or in an aqueous weak acid comprising an oxyanion.
Patent WO-2022140487-A1 (WO)
Inventor: HAN SHAOBO
IPC: G01H9/00
Filed: 2021-12-21
Abstract: Aspects of the present disclosure describe an unsupervised context encoder-based fiber sensing method that detects anomalous vibrations proximate to a sensor fiber that is part of a distributed fiber optic sensing system (DFOS) such that damage to the sensor fiber by activities producing and anomalous vibrations are preventable. Advantageously, our method requires only normal data streams and a machine learning based operation is utilized to analyze the sensing data and report abnormal events related to construction or other fiber-threatening activities in real-time. Our machine learning algorithm is based on waterfall image inpainting by context encoder and is self-trained in an end-to-end manner and extended every time the DFOS sensor fiber is optically connected to a new route. Accordingly, our inventive method and system it is much easier to deploy as compared to supervised methods of the prior art
Patent WO-2022094501-A1 (WO)
Title: Targeting of src-3 in immune cells as an immunomodulatory therapeutic for the treatment of cancer
Inventor: O'MALLEY BERT W
IPC: A61P37/02
Filed: 2021-08-27
Abstract: The present disclosure concerns methods and compositions related to cancer treatment comprising targeting of SRC-3 in immune cells, including T cells such as T regulatory cells. The targeting of SRC-3 in T regulatory cells in particular is effective to eradicate tumors in mammals. In specific cases, the T regulatory cells are subjected to CRISPR  ex vivo  to produce cells suitable for adoptive cell transfer. In some cases, one or more agents that target SRC-3 are also administered to the individual and/or are exposed to the cells prior to administration.
Patent WO-2022115823-A1 (WO)
Inventor: BOURQUE LANCE L
IPC: H03F1/08
Filed: 2021-11-02
Abstract: La présente invention concerne un appareil et des procédés pour la compensation de fréquence d'amplificateurs. Dans certains modes de réalisation, un amplificateur comprend un transistor d'entrée (qui peut faire partie d'une paire d'entrée différentielle) connecté électriquement à un premier nœud, un transistor cascode replié connecté électriquement entre le premier nœud et un deuxième nœud, une source de courant connectée électriquement à un troisième nœud, un transistor de source de courant connecté électriquement entre le troisième nœud et le premier nœud, un premier transistor de sortie ayant une entrée (par exemple, une grille) connecté électriquement au deuxième nœud et une sortie (par exemple, un drain) connectée électriquement à un quatrième nœud, et un condensateur de compensation de fréquence connecté électriquement entre le quatrième noeud et le troisième nœud.
Patent WO-2023121684-A1 (WO)
Inventor: WEN CHIEN-HUI
IPC: G09G3/20
Filed: 2021-12-22
Abstract: An example method includes measuring, from a device having a display panel, a plurality of luminance values for a plurality of pixels located along a cross-section of the display panel. The method includes selecting, based on the measured luminance values, a target luminance value. The method includes determining a luminance compensation profile for the input gray level at the given refresh rate. The luminance compensation profile comprises ratios of the measured plurality of luminance values to the target luminance value. The method includes storing, at the device, the luminance compensation profile. Subsequent to the storing, the device is configured to adjust input display data using the luminance compensation profile for an input gray level when the display panel is providing a display. The luminance compensation profile maintains a color uniformity of the display.
Patent WO-2022155092-A1 (WO)
Inventor: LEONCINI ANDREA
IPC: C07F11/00
Filed: 2022-01-10
Abstract: L'invention concerne des complexes de coordination de molybdène (0) comprenant au moins un ligand cycloheptatriène et éventuellement un ou plusieurs ligands neutres qui se coordonnent au centre métallique par carbone, azote ou phosphore. La présente invention concerne des procédés de dépôt de films contenant du molybdène sur un substrat. Le substrat est exposé à un précurseur de molybdène et à un réactif pour former le film contenant du molybdène (par exemple, du molybdène élémentaire, de l'oxyde de molybdène, du carbure de molybdène, du siliciure de molybdène, du nitrure de molybdène). Les expositions peuvent être séquentielles ou simultanées.
Patent WO-2022173762-A1 (WO)
Inventor: DAVIS ALAN WESLEY
IPC: G08B21/24
Filed: 2022-02-08
Abstract: La présente invention concerne un système PPE-N qui comprend des composants PPE, des étiquettes intelligentes, des lecteurs d'étiquettes intelligentes configurés pour réaliser une détection dans des plages de travail, déclencher des alarmes audiovisuelles et envoyer un avertissement à une personne prédéterminée, et un concentrateur qui compare les signaux provenant des étiquettes intelligentes pour aider à évaluer la santé du composant PPE-N. La présente invention comprend en outre des points de cheminement pour vérifier que le composant PPE soit conforme aux exigences du composant PPE et déterminer si le composant PPE est autorisé dans une zone prédéterminée.
Patent WO-2022178212-A1 (WO)
Title: Compositions et méthodes d'amélioration de réponses immunitaires
Inventor: LAYTON SHERRYLL
IPC: A61K39/00
Filed: 2022-02-18
Abstract: L'invention concerne un vecteur vaccinal comprenant un premier polynucléotide codant pour le polypeptide antigénique choisi dans le groupe constitué par SEQ ID No : 1, SEQ ID No : 2, SEQ ID No : 3, SEQ ID No : 4, SEQ ID No : 5, SEQ ID No : 6, SEQ ID No : 7, SEQ ID No : 8, SEQ ID No : 9, ou toute association de ceux-ci.
Patent WO-2022211931-A1 (WO)
Title: Measurement techniques for reporting beams
Inventor: TAHERZADEH BOROUJENI MAHMOUD
IPC: H04B7/08
Filed: 2022-02-23
Abstract: Methods, systems, and devices for wireless communications are described. In some examples, a user equipment (UE) may identify a configuration for reporting a set of directional beams and measurement information for the set of directional beams to a base station. The configuration may include a first metric for selecting the set of directional beams and a second metric for determining the measurement information. During a beam management procedure, the UE may select the set of directional beams according to the first metric and transmit a report indicating the selected set of directional beams along with the measurement information according to the second metric.
Patent WO-2022182905-A1 (WO)
Title: Stochastic noise layers
Inventor: ESMAEILZADEH HADI
IPC: G06N3/04
Filed: 2022-02-24
Abstract: Provided is a process including: obtaining, with a computer system, with a stochastic layer of a multi-layer neural network, inputs to the stochastic layer from, wherein the multi-layer neural network comprises both deterministic layers and the stochastic layer, and the stochastic layer comprises a plurality of parameters that vary stochastically according to respective probability distributions; determining values of the plurality of parameters by randomly sampling from the statistical distributions; determining an output of the stochastic layer based on both the determined values of the plurality of parameters and the inputs to the stochastic layer; and providing the output of the stochastic layer to a downstream layer of the multi-layer neural network or as an output of the multi-layer neural network.
Patent WO-2022197472-A1 (WO)
Inventor: TIPTON ROBERT
IPC: F03B11/00
Filed: 2022-03-06
Abstract: A Process for Generating Unlimited Sustainable Energy From the Oceans at Extremely Low Cost is disclosed. This process is able to extract useful energy in the form of electricity, compressed air and/or hydrogen gas at a Life Cycle Cost (LCC) 2% or less than the lowest cost technologies in use in 2021. It is a comprehensive, omnibus process consisting of several options which may used singly or in combination. The process is sustainable, scalable, allows staged incremental deployment, utilizes common off the shelf materials, poses little risk to sea life, is capable of being carbon dioxide negative and is able to provide active cooling of the earth by means of low cost electromagnetic pass band emitters.
Patent WO-2022197649-A1 (WO)
Title: Phloroglucinol acetaldehyde resins, methods of making, and uses in rubber compositions
Inventor: ITAHASHI TAMON
IPC: C09J109/08
Filed: 2022-03-15
Abstract: The phloroglucinolic acetaldehyde resin includes multiple phloroglucinolic units defined by formula (I) wherein the number of phloroglucinolic unit is an integer from 2 to 20, and at least one of R1, R2, and R3 combines with a second phloroglucinolic unit to form a methyl-substituted methylene bridge, where in the second and third ones of R1,R2 and R3 is a hydrogen atom or combines with another phloroglucinolic unit to form another methyl-substituted methylene bridge, with the proviso that, for any terminal unit of formula (I), any two of R1, R2 and R3 are a hydrogen atom.
Patent WO-2023287461-A1 (WO)
Inventor: TART JAMIE
IPC: A61J1/00
Filed: 2022-03-15
Abstract: The filtration enclosure for ventilation bags is a manually operated respirator. The filtration enclosure for ventilation bags is adapted for use with a patient. The filtration enclosure for ventilation bags is a breathing assistance device that maintains a positive pressure within the lungs of the patient. The filtration enclosure for ventilation bags incorporates a bag valve mask respirator and a containment structure. The containment structure forms a protection space that encloses the bag valve mask respirator such that the bag valve mask respirator can operate while within the containment space. The containment structure is formed as a gas permeable structure. The containment structure forms a filter that filters microorganisms from the gas that flows through the boundary surface formed by the containment structure.