baber/WOPTO huggingface dataset:
Patent CA-2985786-A1 (CA)
Title: Aav isolate and fusion protein comprising nerve growth factor signal peptide and parathyroid hormone
Inventor: CHIORINI JOHN A
IPC: C12N15/86
Filed: 2016-05-12
Abstract: The invention provides an adeno-associated viral (AAV) vector comprising a capsid comprising the amino acid sequence of SEQ ID NO: 4 or SEQ ID NO: 9, wherein the AAV vector further comprises a heterologous nucleic acid sequence, and wherein the heterologous nucleic acid sequence can encode the NGF-PTH fusion polypeptide or methylmalonyl CoA mutase enzyme. The invention also provides a polypeptide comprising nerve growth factor (NGF) signal peptide and parathyroid hormone (PTH), wherein the polypeptide can comprise, consist essentially of, or consist of the amino acid sequences of SEQ ID NO: 1 and SEQ ID NO: 2. The invention provides a nucleic acid encoding the polypeptide, a vector comprising the nucleic acid, and a composition comprising the polypeptide, nucleic acid, or vector, as well as treatment methods comprising the polypeptide, nucleic acid, vector, or composition. The invention further provides a method of treating methylmalonic acidaemia (MMA) in a mammal comprising administering an AAV vector comprising a heterologous nucleic acid sequence encoding methylmalonyl CoA mutase enzyme to the mammal.
Patent CA-2986726-A1 (CA)
Inventor: PERRY SHAWN F D
IPC: H02G9/00
Filed: 2017-11-27
Abstract: The following invention as described in the abstract, background, summary or throughout this documet and depicted in drawings may use singular which does not exclude plural (and vice versa) when the sense allows. The invention is a singular or modular support or system for use with and for the support of flexible, semi-flexible or ridged conduit, pipe, or similar; herein referred to as conduit which is comprised of one or more sections which complete the underlying framework for conduits and the means in which they are supported and guided. The invention when desired provides anti-static and anti-galvanic self-supporting means independent of physical attachment to building structures whether roof surface, floors, or any other building construction including direct placement on such surfaces. The invention also provides support when ground surface support is needed outside of a building structure. The system is component based providing support where needed as required my mechanical drawings, building codes and load bearing factors to support any conduit system without prejudice to size or the number of conduits that require support. The invention provides support at key areas for conduit, including electrical wiring. The invention will not only provide support for long conduit runs where determined by load bearing factors, codes, standards, building designers, trades persons etcetera but also provide support at where joining is required, at change of direction or attachment points within the conduit system. Such examples of this are 90 degree turns, tee fittings, couplings, valves, junction boxes or any place the conduit system needs support.
Patent CA-2990764-A1 (CA)
Inventor: EDER JORG
IPC: C07K16/36
Filed: 2016-06-24
Abstract: La présente invention concerne des anticorps monoclonaux et leurs fragments de liaison à l'antigène qui se lient au facteur XI humain et au facteur XI activé ("Facteur XIa"), ainsi que des compositions pharmaceutiques et des méthodes de traitement les comprenant.
Patent CA-2991996-A1 (CA)
Inventor: HEWITT RANDALL
IPC: E05B1/02
Filed: 2018-01-16
Abstract: Replacement handle systems and methods involving: a replacement handle having two distal ends, the replacement handle including at least one of: a polymer material, a metallic material, a ceramic material, and a composite material; and an adhesive component for coupling the replacement handle with an appliance door surface, the adhesive component including at least one of a foam pad and an adhesive material, the adhesive component providing a high-strength bond between the replacement handle and the appliance door surface, and the adhesive component having an adhesive strength in a minimum range of approximately 1.1 MPa to approximately 1.8 MPa, whereby decoupling of the replacement handle from the appliance door surface is minimized.
Patent CA-2994044-A1 (CA)
Title: Mammalian follicle-stimulating hormone composition with increased stability
Inventor: GOLETZ STEFFEN
IPC: A61K47/10
Filed: 2016-09-16
Abstract: The present invention pertains to the field of gonadotropins. In particular, an improved composition comprising recombinant human follicle-stimulating hormone and chlorocresol is provided. This improved composition has an increased stability at high temperatures and is useful in the treatment of infertility, in particular in human patients.
Patent CA-2994158-A1 (CA)
Inventor: MAGIN CHELSEA MARIE
IPC: A61L27/54
Filed: 2016-07-29
Abstract: Disclosed herein is an article including a substrate having at least one surface that has a texture and a first type of growing cells, wherein an average length of features that form the texture is operative to facilitate cell growth, cell orientation, cell morphology and cell differentiation. Disclosed herein too is a method including forming a first layer of a polymeric material on at least one surface of a substrate; texturing the first layer to form a textured first layer; and forming a first type of growing cells on the textured first layer, wherein an average length of features that form the textured first layer is operative to facilitate cell growth, cell orientation, cell morphology and cell differentiation.
Patent CA-2996040-A1 (CA)
Inventor: FAN YIJING
IPC: E21B47/12
Filed: 2015-09-23
Abstract: An electromagnetic telemetry system may include an electrically conductive member, a transmitter coupled to the electrically conductive member, the transmitter configured to induce an alternating current along the electrically conductive member, the alternating current representing encoded information, a first receiver coupled to the electrically conductive member, the first receiver configured to receive electromagnetic waves resulting from the alternating current, a second receiver positioned at a location apart from the first receiver, the second receiver configured to receive the electromagnetic waves resulting from the alternating current, and a receiver processing system communicatively coupled to the first receiver and the second receiver, the receiver processing system configured to process the electromagnetic waves received by the first receiver and the second receiver into a combined signal, and decode the combined signal.
Patent CA-2997907-A1 (CA)
Title: Structure de support pour contenant ou ustensiles
Inventor: KOUFOS GENA
IPC: B65D25/20
Filed: 2015-09-08
Abstract: La présente un appareil de support de contenant qui peut comprendre un corps de base qui comporte une première partie, une seconde partie, et une région limite entre les première et seconde parties. L'appareil peut comprendre un premier élément raccord latéral droit et un second élément raccord latéral droit, chacun formé au moins en partie à partir de la première partie du corps de base. L'appareil peut comprendre un élément de support inférieur disposé dans une position coplanaire conjointement avec la première partie du corps de base dans un état non déployé. Les premier et second éléments raccords latéraux peuvent subir une inclinaison angulaire descendante conjointement avec l'élément support inférieur qui subit une translation verticale et une rotation plane simultanées par rapport à la seconde partie du corps de base durant la transition de l'état non déployé à un état déployé, et l'élément de support inférieur peut maintenir une orientation parallèle par rapport à la seconde partie du corps de base durant cette transition.
Patent CA-2998197-A1 (CA)
Inventor: GARRISH ROBERT
IPC: A61F5/01
Filed: 2016-09-08
Abstract: A hinge for a brace comprises a tensioning element such as an inelastic cord for applying a restorative force to the hinge. A tensioning mechanism, preferably a hydraulic spring, tensions the cord as the hinge is moved from a rest position to a loaded condition. A tensioning member having a peripheral cam surface applies a tensioning force to the cord as the hinge is moved out of the rest position. The tensioning block and the anchoring block may be operatively geared together along an arc of motion so as to provide a generally symmetrical motion of the tensioning and anchoring portions relative to the gusset. When an external force is applied to move the hinge from the rest position the tension on the cord loads the spring, and when the external force is removed the spring applies a restorative force to move the hinge back to the rest position. Optionally the tensioning member may be configured to be disengaged and reengaged by an external actuator.
Patent CA-2999779-A1 (CA)
Inventor: CHENG ZHAN
IPC: C08L33/12
Filed: 2015-10-16
Abstract: Certain films comprising polyethylene and poly (methyl 2-methylpropenoate) have unique aesthetic or performance properties.
Patent CA-2999820-A1 (CA)
Title: Compositions comprenant des triterpenoides
Inventor: HAZAN ZADIK
IPC: A61K36/22
Filed: 2016-09-22
Abstract: L'invention concerne des compositions et des formulations comprenant au moins un acide triterpénoïque et au moins un triterpénoïde neutre et leurs utilisations pour traiter un accident vasculaire cérébral ou un traumatisme ainsi que les effets secondaires y étant liés.
Patent CA-3002745-A1 (CA)
Title: Methods for culturing cells and kits and apparatus for same
Inventor: GERMEROTH LOTHAR
IPC: G01N1/30
Filed: 2016-10-20
Abstract: Provided herein are methods that relate, in some aspects, to the incubation or culturing, such as to induce stimulation of expansion (proliferation), activation, costimulation and/or survival, of a composition of cells, such as a population of lymphocytes.   In some aspects, provided are methods and reagents for the stimulation, e.g., of expansion (proliferation), survival or persistence, activation, costimulation, or other effect, of cell populations that involve binding of agents to a molecule on the surface of the cells, thereby providing one or more signals to the cells. In some cases, the reagents are reagents containing a plurality of binding sites for agents, such as multimerization reagents, and thus the one or more agents are multimerized by reversibly binding to the reagent, e.g., thereby creating a stimulatory reagent (multimerized agent), having stimulatory agents multimerized thereon. In some aspects, the multimerized agent can provide for expansion or proliferation or other stimulation of a population of cells, and then such stimulatory agents can be removed by disruption of the reversible bond. Also provided are compositions, apparatus and methods of use thereof.
Patent CA-3004124-A1 (CA)
Title: Pigment de securite, resine polymere luminescente et procede de production
Inventor: KECHT JOHANN
IPC: D21H21/40
Filed: 2016-11-09
Abstract: La présente invention concerne une particule pigmentaire destinée à des applications de sécurité, comprenant une matrice duromère dans laquelle sont noyées une pluralité de particules-noyaux faites d'un polymère thermoplastique comprenant une matière caractéristique dissoute dans les particules-noyaux, la matière caractéristique étant une matière organique ou organo-métallique. L'invention concerne par ailleurs un procédé pour produire des pigments de sécurité, par ex. des pigments de pression luminescents, par introduction dans une matrice duromère de particules polymères thermoplastiques dans lesquelles est respectivement dissoute la matière luminescente.
Patent CA-3004317-A1 (CA)
Title: Tringlerie de barre stabilisatrice a bague
Inventor: HARVEY RICHARD W
IPC: B60G21/055
Filed: 2016-11-10
Abstract: La tringlerie de barre stabilisatrice selon l'invention relie une barre stabilisatrice à un bras de commande d'un système de suspension de véhicule. La tringlerie comprend un élément de fixation et une pluralité de bagues qui sont disposées entre l'élément de fixation et la barre stabilisatrice et entre l'élément de fixation et le bras de commande. Au moins l'une des bagues est construite en tant que pièce de matériau unique, présente une surface externe, un trou interne qui s'étend le long d'un axe pour recevoir l'élément de fixation et une pluralité de poches. Les poches sont espacées radialement entre le trou interne et la surface externe pour permettre à la bague de fléchir et d'absorber plus facilement l'énergie tout en transférant des forces entre la barre stabilisatrice, l'élément de fixation et le bras de commande.
Patent CA-3005780-A1 (CA)
Inventor: MURAKAMI KATSUYA
IPC: G03G15/06
Filed: 2010-03-30
Abstract: Il est décrit un conteneur de distribution de développeur comportant : une chambre de distribution de développeur ayant une ouverture de distribution pour permettre la distribution dun développeur; une chambre configurée pour accueillir le développeur, cette chambre étant rotative par rapport à la chambre de distribution; une partie dengrenage configurée et placée pour recevoir une force rotationnelle pour faire tourner la chambre accueillant le développeur; une partie de pompe configurée et positionnée pour agir au moins sur la chambre de distribution pour distribuer le développeur, la partie de pompe ayant un volume changeant on fonction du mouvement alternatif; et une partie de convertisseur dentraînement configurée et placée pour convertir la force rotationnelle reçue par la partie dengrenage en une force dactionnement de la partie de pompe.
Patent CA-3006745-A1 (CA)
Inventor: MASUMOTO SATORU
IPC: C07F7/10
Filed: 2011-11-02
Abstract: Based on a need for the development of a new type of drug that has a fungicidal activity on drug-sensitive fungi and drug-resistant fungi, the present invention provides a novel fungicide having an excellent fungicidal activity. The compound used as the fungicide of the present invention is an ethynylphenylamidine compound or a salt thereof represented by Formula (4): (see formula 4) wherein R4, R5, R6, and R7 are each hydrogen, halogen, etc.; and R8 is C1-20 alkyl, C3-8 cycloalkyl, C1-4 haloalkyl, a heterocyclic group, or -(CH2)n-Si(R) (R10) (R11) wherein R9, R10, and R11 are each C1-6 alkyl, and n is 1.
Patent CA-3006898-A1 (CA)
Inventor: JACQUEL NICOLAS
IPC: C08J5/18
Filed: 2016-12-02
Abstract: The invention relates to a thermoplastic polyester comprising: at least one 1,4 : 3,6-dianhydrohexitol unit (A); at least one alicyclic diol unit (B) other than 1,4 : 3,6-dianhydrohexitol units (A); at least one carboxylic diacid unit (C) selected from among furan-2,5-dicarboxylic acid, 2,6-naphthalic acid and isophthalic acid units, said polyester including at least 10% 1,4 : 3,6-dianhydrohexitol units (A) and being free from ethylene glycol and terephthalic acid units. The invention also relates to the production method and use of same.
Patent CA-3009545-A1 (CA)
Title: Use of a type ii photoinitiator system for crosslinking silicone compositions
Inventor: PIBRE GUILLAUME
IPC: C09D183/04
Filed: 2016-12-22
Abstract: The invention relates to a silicone composition C that can be crosslinked by exposing same to radiation at a wavelength of 200 to 450 nm, said composition comprising: - at least one radical photoinitiator A; and - at least one coinitiator B selected from among the compounds comprising at least one hydrogen atom linked to a silicon atom.
Patent CA-3014333-A1 (CA)
Inventor: CRONK PAUL ANDREW
IPC: F21V23/00
Filed: 2017-02-21
Abstract: A luminaire (61) is disclosed with a close coupled ballast (62) having a support arm (66) from which is suspended or hung a reflector, and preferably a variable focus reflector (41), having either a single ended lamp (3) or double ended lamp (23). The luminaire (61) is supported from a greenhouse rafter (9) by filaments (10, 11) which are connected one to the ballast (62) and the other to the free end of the support arm (66). In one embodiment the arm (66) is connected to a rigid side plate (64) which is mounted on the ballast (62). In another embodiment the arm (66) is connected to a side plate (164) which is hinged. The arrangement enables flimsy reflectors (41) to be close coupled with electronic ballasts in a way which minimises Radio Frequency Interference (RFI).
Patent CA-3015110-A1 (CA)
Inventor: JOHNSON MIKALA
IPC: H01Q3/24
Filed: 2017-03-01
Abstract: A method and apparatus is disclosed herein for acquiring and tracking a satellite signal with an antenna. In one embodiment, the method comprises a) perturbing one or more of roll, pitch and yaw angles of an antenna orientation to create variant orientations associated with a first search pattern; b) computing new scan and polarization angles, in response to perturbed roll, pitch and yaw angles, for each of the variant orientations; c) receiving a radio-frequency (RF) signal from a satellite for each of the variant orientations; d) generating one or more receiver metrics representing a received RF signal associated with each of the variant orientations; e) selecting, as a new orientation, one of the variant orientations based on the one or more receiver metrics; and f) repeating a)-e) with the new orientation with a second search pattern narrower than the first search pattern.
Patent CA-3015422-A1 (CA)
Inventor: PIECH GREGOR ANTON
IPC: B65D17/00
Filed: 2017-02-07
Abstract: The invention relates to a can lid of a conventional design, in particular intended for beverage cans, whose special feature comprises the fact that a substantially ring-shaped molded plastic part is fastened to the lower side of the lid surface surrounding the opening region to form an opening that is sealingly reclosable, in that a plastic stopper part is fixedly connected to the lower side of the tongue tab that is upwardly pivotable during the opening procedure and sealingly engages into the molded part, and in that the peripheral contour of the tongue tab is preferably disposed in the region of the molded part at a predefinable spacing from the stopper part.
Patent CA-3018697-A1 (CA)
Inventor: KOIKE TOMOYUKI
IPC: H01M2/10
Filed: 2017-03-13
Abstract: Provided is a power supply system which is provided with two secondary batteries having different charge and discharge characteristics, and which is able to be mounted on a vehicle. This power supply system is provided with, as the two secondary batteries, a lead acid storage battery that is connected to an electrical load and a lithium ion storage battery that is connected to the electrical load in parallel with the lead acid storage battery via two paths, namely a first path and a second path. In addition, the power supply system is provided with: a power generator which is capable of charging the lead acid storage battery and the lithium ion storage battery; a first switch that is provided on the first path; a second switch that is provided on the second path; an electrical resistor element that is provided on the second path and has a resistance higher than the harness resistance of the first path; and a control means that controls on/off of the first and second switches in accordance with a voltage increase request of the electrical load, while controlling on/off of the power generator.
Patent CA-3019589-A1 (CA)
Title: Accurate molecular barcoding
Inventor: SHUM ELEEN
IPC: C12Q1/68
Filed: 2017-04-28
Abstract: In accordance with some embodiments herein, compositions and methods for accurate barcoding of nucleic acids are described. The compositions and methods involve a plurality of unique oligonucleotide species comprising unique molecule barcodes. The molecular barcodes have a relatively low G (guanine) content, e.g. each of the barcodes contain less than 50% guanine or the overall set of barcodes contain in average less than 12.5% guanine. The set of barcodes is intended to exhibit reduced bias in amplification and analysis.
Patent CA-3026449-A1 (CA)
Inventor: LAM JIMMY
IPC: B62D33/067
Filed: 2017-06-02
Abstract: The longitudinal member (1 ) comprises a front end (6) provided with a hinge element (10) for attaching the longitudinal member in an articulated manner to a heavy goods vehicle body (2), and a rear end (8) comprising an attachment element (12) for attaching the longitudinal member in a non-permanent manner to the heavy goods vehicle body (2), the longitudinal member comprising a front part (14) extending from the front end (6) to an intermediate area (16) of the longitudinal member and a rear part (18) extending from the intermediate area (16) to the rear end (8) of the longitudinal member. The product (PF) of the wall thickness (tF) of the front part (14) by the yield strength (YsF) of the material of the front part (14) is greater than the product (PR) of the wall thickness (tR) of the rear part (18) by the yield strength (YsR) of the material of the rear part (18).
Patent CA-3026878-A1 (CA)
Inventor: MCCUTCHEN DAVID J
IPC: C02F11/127
Filed: 2017-06-05
Abstract: Cette invention concerne un appareil de filtration comprenant une charge de boue contenant un liquide, des solides et des gaz introduits dans un réservoir, le réservoir contenant au moins un filtre de séparation par centrifugation comprenant un ensemble de cônes de filtre ayant un tamis de filtre, et un cône de barrière, disposés grossièrement en parallèle, et définissant entre eux un espace de travail conique, l'espace de travail conique ayant une ouverture périphérique vers le réservoir et une ouverture centrale communiquant avec l'intérieur d'un ou de plusieurs arbres creux supportant le cône de barrière et le cône de filtre, l'arbre supérieur supportant le cône de barrière possédant un canal axial supérieur pour la sortie de gaz, l'arbre inférieur supportant le centre du cône de filtre possédant un canal axial inférieur pour la sortie de liquide ou d'huile, des moyens de moteur pour produire une rotation dans ledit au moins un filtre de séparation par centrifugation, et un réservoir de liquide de filtrat situé sous le cône de filtre pour capturer le filtrat passant à travers le tamis de filtre.
Patent CA-3027941-A1 (CA)
Title: Interprocess communication facilitating sellside marketmaking
Inventor: LUTNICK HOWARD W
IPC: G06Q30/02
Filed: 2017-06-14
Abstract: An electronic exchange platform configured to: receive respective list of approved Buyside participants for each of a plurality of marketmaking orders; receive a respective marketmaking order for a side of trades on the financial instrument from each of the plurality of Sellside participants; peg a price for the received marketmaking orders to a price relative to and multiple ticks behind a best price on the side in an order book; present market information to Buyside participants identifying marketmaking orders for which the Buyside participants are approved; receive a contra order from a Buyside participant that is approved to trade with a subset of the plurality of marketmaking orders, in which the contra order identifies preferred Sellside participants; distribute the contra order; and determine new best bid and offer in response to the distribution; and adjust remaining marketmaking offers to retain peg in response to determining new best bid or offer.
Patent CA-3028710-A1 (CA)
Inventor: JOUHIKAINEN HANNES MIKAEL
IPC: G06N20/00
Filed: 2017-06-22
Abstract: Un procédé de reconnaissance d'un objet dans un flux vidéo peut consister à recevoir un flux vidéo provenant d'une source vidéo, le flux vidéo comprenant une pluralité de trames vidéo. Le procédé peut consister à sélectionner au moins une trame vidéo parmi les images vidéo selon un taux de sélection de trame. Le procédé peut consister à diviser la trame vidéo sélectionnée en une première pluralité de blocs d'image. Le procédé peut également consister à reconnaître, parmi la première pluralité de blocs d'image, une seconde pluralité de blocs d'image qui comprennent une image d'un objet, la reconnaissance étant basée sur un paramètre de reconnaissance d'image déterminé par un algorithme d'apprentissage machine. Le procédé peut consister à déterminer qu'au moins l'un de la seconde pluralité de blocs d'image correspond à l'objet sur la base d'une métrique de probabilité, la métrique de probabilité étant déterminée par le processeur sur la base au moins du taux de sélection de trame.