baber/WOPTO huggingface dataset:
Patent IL-162214-A0 (IL)
Title: Pyridine derivatives and pharmaceutical compositions containing the same
IPC: A61K31/4436
Filed: 2002-12-06
Abstract: The present invention relates to compositions comprising 1,2-dihydropiridin-2-one compounds and an immunoregulatory or anti-inflammatory agent. The compositions are useful for the prevention or the treatment of neurodegenerative diseases, for example demyelinating disorders.
Patent IL-162601-A0 (IL)
Title: Raf/ras binding proteins, their preparation and use
IPC: C12N1/15
Filed: 2002-12-20
Abstract: The invention provides novel means to inhibit the Mitogen Activated Protein Kinases (MAPKs) pathway activated by Ras/Raf complex using GILZ protein related compounds as inhibitors of Raf/Ras-mediated signal transduction. Pharmaceutical compositions containing such compounds are also disclosed.
Patent IL-163873-A0 (IL)
Title: Il-2 independent feline derived T cell
IPC: A61K39/21
Filed: 1996-08-23
Abstract: The subject invention pertains to novel methods and compositions for protecting cats from infection by a broad range of FIV strains using a multi-subtype FIV vaccine. Multi-subtype FIV vaccines comprising either cell free whole virus or cell lines infected with viruses are described. Methods for vaccinating cats with the subject vaccine compositions are also described. Cats vaccinated according to the methods and compositions of the subject invention exhibit protective humoral and cellular immune responses to FIV when challenged with homologous or heterologous strains of FIV. The subject invention also pertains to novel feline cell lines that are susceptible to infection by FIV and their methods of use.
Patent IL-164941-A0 (IL)
Title: Indole derivatives and the use thereof as cb2 receptor ligands
IPC: A61P1/18
Filed: 2004-10-31
Abstract: 3-(Aryl-(hydroxyimino)-methyl)-1-(substituted alkyl)-1H-indole derivatives (I) are new.  Indole derivatives of formula (I) and their salts and/or solvates are new.  Ar  =  (a) phenyl substituted by 1-3 of halo, T, CF3, NH2, NO2, OH, OT, ST and SO2T or (b) naphthyl optionally substituted by 1 or 2 of halo, T and CF3;  T  =  1-4C alkyl;  A  =  2-6C alkylene;  Y  =  SR4, SOR4, SO2R4, SO2NR5R6, N(R7)SO2R4, OR4 or N(R7)SO2NR5R6;  R1, R3, R'3  =  H, halo, OH, T, CF3 or OT;  R2, R5 - R7  =  H or T;  R4  =  T or CF3;  R  =  H, T or 2-4C alkenyl.  An Independent claim is included for the preparation of (I).
Patent IL-178988-A0 (IL)
Title: Improvements in investment casting
IPC: B22C9/04
Filed: 2006-11-01
Abstract: In an investment casting procedure using microwave energy as the heat source virgin wax models are attached to a spree of wax-type pattern material incorporating a susceptor, the spree having a pour cup also of a wax-type pattern material, the pour cup material having a higher percentage of the susceptor than the material of the spree. In use the pour cup will melt first and the spree second, unblocking the path of the virgin wax so that its expansion will not crack ceramic with which it has been coated.
Patent IL-179542-A0 (IL)
Title: Infusion bag with integrated rinsing system
IPC: A61J1/00
Filed: 2006-11-23
Abstract: The perfusion pouch is made with at least two compartments one compartment (1) containing a medication in the form of a solution, and one or more others (2) containing a solute for rinsing both the medication compartment (1) and the perfusion line (10) once the compartment is emptied. The pouch has a system (6) for connecting/separating the compartments, allowing the rinsing solute to penetrate the medication compartment automatically by the effect of a depression created by the height of the column of water in the perfusion line when the medication compartment is empty. The connecting/separating system can be in the form of a valve, a grained surface or a thermoformed channel.
Patent IL-180309-A0 (IL)
Title: 3-(heteroaryl-oxy)-2-alkyl-1-aza-bicycloalkyl derivatives as alpha.7-nachr ligands for the treatment of cns diseases
IPC: C07D487/08
Filed: 2006-12-25
Abstract: The present invention relates to 1-aza-bicycloalkyl derivatives of formula (I)   
wherein the substituents are as defined in the specification, to processes for their production, their use as pharmaceuticals in the prevention and treatment of psychotic and neurodegenerative disorders. The claimed compounds act as nicotinic acelylcholine receptors (NACHR) ligands.
Patent IL-182893-A0 (IL)
Title: PYRAZOLO-[1,5-a] PYRIMIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
Filed: 2007-05-01
Abstract: The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing the compounds of the invention.
Patent IL-183071-A0 (IL)
Title: Brake force transducer for electric brakes
IPC: F16D65/18
Filed: 2007-05-08
Abstract: An electric brake actuator (10) for the brake system of an aircraft includes a piston (28) driven by a cylindrical nut and screw arrangement (16,18), driven by an appropriate motor of the actuator. Application of brake force results in a reaction force that deflects the top cover (12) of the actuator. The axial component of this deflection correlates directly with the brake force applied. A beam (38) is interposed between this cover (12) and a top cap (34), such that deflection of the beam correlates to applied brake force. Piezo-resistive devices are connected to the beam (38) and, through a Wheatstone bridge, provide an electrical output signal correlating to applied brake force.
Patent IL-188362-A0 (IL)
Title: Attenuated negative strand viruses with altered interferon antagonist activity for use as vaccines and pharmaceuticals
IPC: A61P35/00
Filed: 2007-12-24
Abstract: The present invention relates, in general, to attenuated negative-strand RNA viruses having an impaired ability to antagonize the cellular interferon (IFN) response, and the use of such attenuated viruses in vaccine and pharmaceutical formulations. The invention also relates to the development and use of IFN-deficient systems for selection of such attenuated viruses. In particular, the invention relates to attenuated influenza viruses having modifications to the NS1 gene that diminish or eliminate the ability of the NS1 gene product to antagonize the cellular IFN response. The mutant viruses replicate in vivo but demonstrate reduced pathogenicity, and therefore are well suited for live virus vaccines, and pharmaceutical formulations.
Patent IL-215624-A0 (IL)
Title: Fluid density measurement device
Filed: 2011-10-09
Abstract: A device for determining a density of a fluid is described. The devices comprises a mechanical resonator, a driver/receiver unit arranged to provide an actuation to the mechanical resonator, sense a response of the mechanical resonator to the actuation, and provide an output signal representing the response; and an evaluation unit. The evaluation unit of the device is arranged to 
i. determine an oscillation distribution from the output signal, 
ii. determine a resonance frequency estimate from the oscillation distribution, and 
iii. determine the density of the fluid based upon the resonance frequency estimate.  The device according to the invention enables a more accurate determination of the fluid density for fluids comprising immiscible components (thus forming a heterogeneous mixture), like a water-oil emulsion, or a fluid with occluded gas.
Patent RO-126799-A0 (RO)
Title: Integrated system for programming and management of complex production processes
Inventor: IONESCU MIRCEA DAN
IPC: G05B19/18
Filed: 2010-11-22
Abstract: The invention relates to an integrated system for programming and management of production processes for high-risk complex pieces and assemblies. According to the invention, the system consists of a module for programming the processes concerning the design of complex palletted surfaces, a module for production programming based on the selection of the manufacturing process and suitable programming methods using mathematic models and models for the optimization of high-speed lathing processes as compared with the kinematics and dynamics of the machine-tools, a module for production monitoring on the on-line updated flow sheet due to data acquisitions from readers mounted in the working points, some modules for viewing the programming graphs and monitoring the production, as well as some modules for issuing the documents certifying the execution conformity.
Patent AP-2000001817-A0 (AP)
Title: Process for the production of cereal granules for porridges.
Inventor: JEGEDE OYELAYO
IPC: A23L1/00
Filed: 2000-05-08
Abstract: The invention relates to a process for the production of cereal granules for porridges, which comprises feeding cereal flour onto bottom surface of a rotating, inclined pan, spraying water on said surface until granules are formed of a predetermined mean particle size of 1 to 4mm 0 and drying the granules formed in a fluidised bed drier, the cereal flour being selected from that of maize, millet, wheat, sorghum, rice and fonio.
Patent CU-21843-A1 (CU)
Title: Diodo conmutador metal aislador semiconductor con heteroestructura monocristalina
Inventor: MADER MICHAEL
IPC: H01L49/02
Filed: 1987-04-04
Abstract: El diodo conmutador metal aislador semiconductor con heteroestructura monocristalina es utilizado en la rama electrónica. El dispositivo objeto de invención, posibilita la alta integración debido a su estructura formada por capas totalmente monocristalinas cuya tecnología de fabricación es compatible con la técnica de epitaxia por haces moleculares. El diodo desarrollado comprende una capa aislante monocristalina sobre un substrato semiconductor monocristalino y los contactos metálicos también monocristalinos. Esta estructura con parámetros electrofísicos reproducibles en un ciclo tecnológico único se fabrica mediante la técnica de crecimiento por epitaxia con haces moleculares de los materiales apropiados tales como los fluoruros - alcalino terreo sobre Silicio y Arseniuro de Galie, así como los silicatos epitaxiales con conductividad metálica. Son factibles las aplicaciones de estos dispositivos en sistemas analógicos y digitales en específico sensores ópticos y memorias de alta capacidad.
Patent ZM-1788-A1 (ZM)
Title: Process for common separation of contaminating elements from electrolyte solutions of valuable metals
IPC: C22B3/00
Filed: 1988-04-05
Abstract: A process for the common or simultaneous separation of arsenic, antimony, bismuth and iron from electrolyte solutions of valuable metals by solvent extraction and subsequent recovery of the contaminating elements, which process is characterized in that aqueous mineral-acidic electrolyte solutions of valuable metals are admixed with a sparingly water soluble organic solvent containing at least one hydroxamic acid, the aqueous and organic phases are thoroughly mixed, the contaminating elements arsenic, antimony and bismuth are precipitated from the organic phase by direct sulfide precipitation, the sulfides are separated, and the extracted iron is subsequently reextracted with a water soluble iron-complexing agent into an aqueous phase and recovered.
Patent LU-82499-A1 (LU)
Inventor: MINEUR M
IPC: B60C17/00
Filed: 1980-06-02
Abstract: A pneumatic safety tire 10 capable of being used in the uninflated condition at a speed up to a maximum predetermined value for a maximum predetermined distance which can then be repaired and returned to normal service, comprises sidewalls 14, 16 which have a configuration such that the bending moment stresses experienced in the sidewall when the tire is operated in the uninflated state do not exceed a predetermined value. The portion 46,48 of the sidewall radially and axially inward of the carcass ply structure 30 is made of an elastomeric material having a dynamic modulus at least equal to or greater than 50 kg/cm<2> and has a ratio of hysteresis to dynamic modulus less than or equal to 24% kg/cm<2>. <IMAGE>
Patent MA-20732-A1 (MA)
IPC: A61Q5/02
Filed: 1986-07-10
Abstract: Shampoos are disclosed which comprise a synthetic anionic surfactant, a dispersed, insoluble, non-volatile silicone, a tri long chain alkyl quaternary ammonium salt or a tri long chain amine, a suspending agent and water.
Patent MA-24696-A1 (MA)
Title: Adaptateur de cosse sur couche mta
Inventor: PAZ SALGAD JUAN ANTONIO
IPC: H04L12/70
Filed: 1998-11-11
Abstract: UN ADAPTATEUR DE COSSE QUI SERT D'ÉLÉMENT FINAL DE LIGNE OPTIQUE DANS DES RÉSEAUX  à BANDE LARGE POUR OPTIMISER L'ACCèS D'UN USAGER OU D'UN RÉSEAU D'USAGER à UN RÉSEAU MTA PUBLIC, EN PERMETTANT à L'USAGER D'ÉTABLIR DES CONNEXIONS POINT - MULTIPOINT,  DE CONFORMER LA TRAFIC POUR L'ACCèS AU RÉSEAU PUBLIC ET LE MESURAGE DE PRESTATIONS DE LA TRASMISSION, SANS INTERROMPRE LE FLUX D'INFORMATION à L'AIDE DE LA CONNEXION D'UN ORDINATEUR PERSONNEL QUI RÉALISE LA GESTION LOCALE DU DISPOSITIF, QUI COMPREND UN MODULE DE COUCHE PHYSIQUE POUR RÉALISER LA CONV ERSION DE SIGNAL OPTIQUE EN UN SIGNAL ÉLECTRIQUE, UN MODULE DE COUCHE MTA Ou SONT ÉXÉCUTÉES LES FONCTIONS DE CONFORMAGE DE TRAFIC, D'OPÉRATION ET DE MAINTENANCE AINSI QUE DE MULTIPLEXAGE,  DE MeME QUE LA CONNEXION AU PORT SÉRIE DE L'ODINATEUR,  ET UN MODULE SYNCHRONISME QUI SÉLECTIONNE LA VITESSE DE TRANSMISSION, EN ENYOYANT LE SIGNALDE SYNCHRONISME CONVENANT AUX AUTRES COMPOSANTS DU DISPOSITIF.
Patent MA-24987-A1 (MA)
Title: Assemblage combine de bois,  marbre et zellidge pour la fabrication de mosaiques decoratives
Inventor: GINGARELLI ALBERTO
IPC: B44C1/28
Filed: 1999-09-24
Abstract: IL S'AGIT D'UN PROCÉDÉ DE FABRICATION DE MOSAiQUES à USAGE DE DÉCORATION (REVeTEMENT MURAL ET DE SOL) CONSTITUÉ DE DIVERS MATÉRIAUX RÉUNIS EMSEMBLE POUR LA PREMIèRE FOIS. LE BOIS, LE MARBRE ET LE ZELLIDGE SONT ASSEMBLÉS EN PLAQUES DE DIVERSES DIMENSIONS PAR LE MOYEN DE RÉSINE, LAINE DE VERRE ET CATALYSEUR SPÉCIFIQUE QUI PERMET à CES MATÉRIAUX D'OFFRIR LA MeME RÉSISRANCE ET LES MeMES CARACTÉRISTIQUES DE REVeTEMENT. POUR QUE LE BOIS ACQUIERT LES SPÉCIFICITÉS DE RÉSISTANCE OFFERTES PAR LE MARBRE ET LE ZELLIDGE, LE PROCÉDÉ UTILISÉ POUR FIXER LE BOIS ET LE MAINTENIR DANS SON ÉTAT INITIAL CONSISTE à LE VISSER PAR DES CORPS MÉTALLIQUES SCELLÉS à LA RÉSINE EN TANT QUE PRODUIT LIANT.
Patent MA-38082-A1 (MA)
Title: Transmission en liaison montante pour agrégation de porteuses par l'intermédiaire de multiples nœuds
Inventor: GAAL PETER
IPC: H04L5/00
Filed: 2013-11-12
Abstract: L'invention concerne une gestion de canal de commande de liaison montante selon laquelle un équipement utilisateur (ue) reçoit une configuration pour de multiples canaux de commande de liaison montante pour une transmission à de multiples nœuds en communication multi-flux avec l'ue. L'ue génère les canaux de commande de liaison montante sur la base de la configuration, chacun des canaux de commande de liaison montante étant généré pour un nœud correspondant parmi les nœuds. L'ue transmet ensuite chacun des canaux de commande de liaison montante au nœud correspondant. Pour des ue permettant des transmissions en liaison montante multiples, dans lesquelles l'ue communique avec au moins l'un des nœuds sur de multiples porteuses composantes (cc), la configuration peut désigner sur laquelle des multiples cc l'ue devrait transmettre le canal de commande de liaison montante pour ce nœud. Pour des ue permettant seulement des transmissions en liaison montante uniques, la configuration peut désigner la transmission des canaux de commande de liaison montante dans des techniques soit de multiplexage par répartition fréquentielle (fdm) soit de multiplexage par répartition temporelle (tdm).
Patent MA-38486-A1 (MA)
Title: Emballage pour traitement antimicrobien de plante
Inventor: KRITZMAN GIORA
IPC: A01P1/00
Filed: 2015-09-18
Abstract: The present invention provides a package (200) comprising at least one first component in the form a well (220), the first component comprising particulate matter comprising at least one natural oil; at least one second component, in the form of a plurality of second wells (230) comprising antagonist(s) of a microbial pathogen; wherein the at least one first component and the at least one second component are contained in separate compartments of said package. Also provided by the present invention is a method for providing an anti- bacterial agent, the method comprising mixing the first component comprising particulate matter carrying at least one natural oil; and at least one second component comprising at least one antagonist of a microbial pathogen, and allowing said mixture to form into an emulsion with anti-bacterial activity. Further provided by the present invention is a method of treating or preventing a pathogen infection in a plant, the method comprises applying to said plant an amount of an emulsion comprising particulate matter, at least one natural oil and at least one antagonist of a microbial pathogen that causes said pathogen infection. Yet further, there are provided some isolated antagonistic bacteria that may be used, inter alia, in the package and methods disclosed herein.
Patent MA-39307-A1 (MA)
Title: Macrocycles à groupes hétérocycliques p2' servant d'inhibiteurs du facteur xia
Inventor: ORWAT MICHAEL J
IPC: C07D487/08
Filed: 2015-01-30
Abstract: La présente invention concerne des composés de formule (i) ou des stéréo-isomères, des tautomères ou des sels de qualité pharmaceutique de ceux-ci. Dans ladite formule, toutes les variables ont la signification indiquée dans la description. Ces composés sont des inhibiteurs sélectifs du facteur xia ou des inhibiteurs doubles de fxia et de la kallicréine du plasma. Cette invention concerne également des compositions pharmaceutiques comportant ces composés et des méthodes pour traiter des troubles thrombo-emboliques et/ou inflammatoires à l'aide de celles-ci.
Patent MA-39560-A1 (MA)
Title: Commande de réseau électrique hiérarchique et répartie
Inventor: MATAN STEFAN
IPC: H02J3/38
Filed: 2015-07-06
Abstract: L'invention concerne un nœud de commande qui permet une commande de réseau électrique et répartie. Le nœud de commande surveille la génération de puissance et l'appel de puissance au niveau d'un point de couplage commun (pcc) entre un réseau de distribution d'énergie électrique et tous les dispositifs en aval du pcc. Le nœud de commande peut avoir un ou plusieurs nœuds consommateurs, qui peuvent être ou comprendre des locaux d'abonné, et une ou plusieurs sources d'énergie connectées en aval. Le nœud de commande surveille et commande l'interface par l'intermédiaire du pcc à partir du même côté du pcc que la génération de puissance et l'appel de puissance. La commande peut consister à ajuster l'interface entre le nœud de commande et la gestion du réseau électrique centrale par l'intermédiaire du pcc afin de maintenir la conformité aux réglementations du réseau électrique au niveau du pcc.
Patent MA-40372-A1 (MA)
Title: Formulation pharmaceutique de cineol et d'amoxicilline
Inventor: ADNANE REMMAL
IPC: A61P31/04
Filed: 2016-06-02
Abstract: La présente invention concerne une formulation pharmaceutique sous forme de poudrecomprenant de l' amoxicilline, du cinéol et une huile pharmaceutiquement acceptable. La5 présente formulation peut en outre comprendre de l'acide clavulanique. Elle est destinée à uneadministration par voie orale, de préférence après suspension dans un solvant aqueux.
Patent MA-44950-A1 (MA)
Title: Composition , notamment composition pharmaceutique préventive et curative , a base de peroxometallate
Inventor: WILMOTTE REMI
IPC: C11D3/48
Filed: 2017-03-29
Abstract: L'invention concerne un mélange ou une composition, de préférence thérapeutiquement actif par voie topique, comprenant : - au moins un sel de métal, le métal étant choisi parmi le molybdène (mo), le tungstène (w), le vanadium (v), l'or (au), un lanthanide, en particulier le lanthane; - au moins un agent chélatant; - au moins une source de radicaux peroxydant; - au moins un agent tampon; ainsi que des compositions pharmaceutiques constituées par ce mélange ou le comprenant, ses procédé de fabrications et ses applications, en particulier pour dans une méthode de traitement thérapeutique d'une infection virale, et en particulier impliquant un virus de la famille herpesviridae; ou anti-inflammatoire.
Patent UY-25604-A1 (UY)
Title: Metodo para la identificacion de inhibidores de la presenilinasa
Inventor: STEINER DR HARALD
IPC: A61P43/00
Filed: 1999-07-09
Abstract: La presente invención proporciona métodos para la identificación de inhibidores de la presenilinasa, sustancias identificables con dichos métodos, su uso en la elaboración de un medicamento para el tratamiento de enfermedades neurodegenerativas, preferentemente la enfermedad de Alzheimer, y composiciones farmacéuticas que los contienen. El método para identificar una sustancia capaz de reducir o eliminar la actividad de la presenilinasa se caracteriza por las siguientes etapas: a) se cultiva una célula o línea celular que expresa dicha actividad de presenilinasa y una proteína de fusión, comprendiendo dicha proteína de fusión la presenilina 1 o presenilina 2 de longitud completa y un reportero, b) dicha célula o línea celular se incuba con un compuesto de ensayo, c) empleando el reportero, se mide la cantidad de proteína de fusión de longitud completa, d) la cantidad de proteína de fusión de longitud completa medida se compara con la cantidad de proteína de fusión de longitud completa medida para un testigo. La etapa c) se caracteriza además por las etapas: a) se inmovilizan sobre una superficie sólida anticuerpos específicos para la porción C-terminal de la presenilina 1 o la presenilina 2, b) se extrae la proteína de dicha célula o línea celular después del cultivo, c) dichos extractos de proteína se incuban con dichos anticuerpos, d) se mide la cantidad de proteína de fusión de longitud completa unida por dichos anticuerpos, mediante la detección del reportero. Estos métodos reducen o eliminan: la segmentación autoproteolítica de la presenilina, la actividad de la gamma-secretasa. Método en el que la sustancia previene la segmentación de la presenilina 1 en fragmentos de segmentación endoproteolítica regulada que son el fragmento N-terminal (NTF) y el fragmento C-terminal (CTF).
Patent UY-25985-A1 (UY)
Title: Elementos de construcción que comprenden un material plástico
Inventor: WOLFOWITZ STEVEN ALAN
Filed: 2000-01-20
Abstract: La necesidad de proveer grandes volúmenes de viviendas de bajo costo, ha conducido a la innovación de una cantidad de elementos para construcción como bloques o ladrillos huecos que son apilables y que pueden llenarse y fijarse de diversas formas. Comprenden un material plástico y ocasionalmente no necesitan ni pintura. Algunos prefieren un acabado revocado y esto es difícil de lograr. Estos bloque son inherentemente deformables, deben ser reforzados para evitar la deformación al rellenarse. La invención consiste en proveer elementos para la construcción huecos y económicos, capaces de ser enyesados y no sufran deformación después de relleno.
Patent UY-26947-A1 (UY)
Title: Técnica de transfección intensificada
Inventor: CHO MYUNG-SAM
IPC: C12N15/85
Filed: 2001-09-26
Abstract: Un sistema vector de expresión génica en células de mamíferos que incluye una pluralidad de plásmidos y comprende: (a) un sistema de mantenimiento episomal; (b) un fuerte promotor/intensificador; (c) un complejo de transactivación de proteínas y (d) ADN que codifica para la proteína heteróloga. Los complejos de mantenimiento episomal y de transactivación de proteínas pueden incluir subelementos situados en el mismo o en diferentes plásmidos dentro del sistema de expresión celular.
Patent UY-27564-A1 (UY)
Title: Combinación farmacéutica.
Inventor: YEADON MICHAEL
IPC: A61K31/437
Filed: 2002-12-05
Abstract: La presente invención se refiere a una combinación de un inhibidor selectivo de PDE4 como se define en la presente memoria y un agonista del receptor B2-adrenérgico, para la administración simultánea, secuencial o por separado por vía inhalada en el tratamiento de una enfermedad obstructiva de la vías respiratorias u otra enfermedad inflamatoria.