baber/WOPTO huggingface dataset:
Patent SK-288919-B6 (SK)
Title: Process for preparing concentrates of aucubin and catalpol from leaves of Plantago species
Inventor: ŠTEFUCA VLADIMÍR
IPC: C07H1/08
Filed: 2018-10-09
Abstract: Concentrate of aucubin and catalpol from leaves of Plantago species is prepared by extracting the leaves in hot water, the extract is then separated by filtration, soluble carbohydrates in the extract are removed by culturing in the presence of microorganisms utilizing monosaccharides and disaccharides (preferably with yeast Saccharomyces cerevisiae), the cells of microorganisms are removed from the medium after culturing, and aucubin and catalpol are isolated from the separated solution by adsorption on activated carbon.
Patent BR-PI0110371-B8 (BR)
Inventor: AMY OLIVER
IPC: A61P17/00
Filed: 2001-04-24
Abstract: Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3K´) activity, and methods of treating diseases, such as disorders of immunity and inflammation, in which PI3K´ plays a role in leukocyte function are disclosed. Preferably, the methods employ active agents that selectively inhibit PI3K´, while not significantly inhibiting activity of other PI3K isoforms. Compounds are provided that inhibit PI3K´ activity, including compounds that selectively inhibit PI3K´ activity. Methods of using PI3K´ inhibitory compounds to inhibit cancer cell growth or proliferation are also provided. Accordingly, the invention provides methods of using PI3K´ inhibitory compounds to inhibit PI3K´-mediated processes in vitro and in vivo.
Patent EP-1370398-B8 (EP)
Inventor: WILSON JOHN E
IPC: B26D7/18
Filed: 2002-03-21
Granted: 2006-03-15
Abstract: A slitter for webs, such as sheet aluminum or other metals, has a simple and effective method and apparatus for controlling the movement of a strip of metallic trim into a scrap reclamation system. One or more air nozzles direct a stream of air between the knife roll and the trim strip in the area where the trim strip leaves the knife roll. This presses the trim strip away from the knife roll, and reduces the risk that trim will adhere to the knife roll and cause problems.
Patent EP-1801114-B8 (EP)
Inventor: HEINDL DIETER
IPC: C07H21/00
Filed: 2005-11-23
Granted: 2009-12-02
Abstract: A modified oligonucleotide, is new. A modified oligonucleotide of structure D-P(B)(A)=N-Acc (I), is new. A : 5' end of nucleotide or nucleotide chain or linker bound to solid phase; B : 3' end of nucleotide or nucleotide chain or a linker; D : OH or CH 3; Acc : electron acceptor or electron acceptor substituted with residue R; R : organic substituent; Acc : -CN, -SO 2-R', 6-membered N +> heterocycle (such as pyridinium, Pyrimidinium or chinolinium) with at least one alkylated N-atom in ortho- or para- position; and R' : amino-substituted alkyl(s), optionally substituted aryl or optionally substituted heterocycle. An independent claim is included for producing a modified oligonucleotide.
Patent EP-1722229-B8 (EP)
Inventor: HERMIDA SANTOS JOSE
IPC: G01N33/564
Filed: 2005-02-03
Granted: 2009-11-25
Abstract: The present invention relates to a method for detecting the presence of high levels of autoantibodies against protein C/activated protein C endothelial receptor (EPCR). The invention is  characterised in that  it comprises  in vitro  detection and quantification of anti-EPCR autoantibodies in a sample.
Patent EP-1814438-B8 (EP)
Inventor: BALDUS HERIBERT
IPC: G06K9/00
Filed: 2005-11-04
Granted: 2009-04-01
Abstract: A wireless sensor network for wirelessly monitoring a medical subject includes a plurality of sensor nodes (22, 24, 26, 122, 124, 126). Each sensor node includes a wireless transceiver (46) for sending and receiving wireless messages, a sensor (40, 42, 130, 132, 140, 142) monitoring a characteristic of the medical subject, and a processor (50). The processor is programmed to at least perform an authentication method including: (i) acquiring sensor data via the sensor for a predetermined time (76) responsive to receiving a wireless trigger message; (ii) storing an association code (60, 150, 152, 160, 162) computed from the acquired sensor data; and (iii) authenticating a subsequently received wireless message containing an association code tag by comparing the association code tag with the stored association code. The processor further attaches the stored association code as the association code tag in messages sent to other sensors.
Patent BR-PI0602271-B8 (BR)
Title: dispositivo de cateter venoso central de longa permanência parcialmente implantável
Inventor: MARCOS AUGUSTO SILVA PIRES E ALBUQUERQUE
IPC: A61M39/02
Filed: 2006-04-26
Abstract: dispositivo de cateter venoso central de longa permanência a presente invenção refere-se a um novo dispositivo para ser implementado no ser humano e que, uma vez conectado à extremidade distal de um tubo de cateter previ-amente posicionado no sistema endovenoso, permita a administração de medicamen-tos por um longo período de tempo sem uso de agulha.
Patent BR-PI0807685-B8 (BR)
Title: sistema de revezamento automático de bomba
Inventor: PIERRE REBOURS
IPC: A61M5/168
Filed: 2008-02-26
Abstract: sistema de revezamento automático de bomba. a presente invenção refere-se a um sistema de revezamento automático de bomba (20 ,42, 94) que inclui controladores (35, 52,54) acoplados a acionadores (22,23,48,50) para descarregar em sequência fluido de uma pluralidade de recipientes de medicação (24, 26) em um acoplador (35) que tem uma barreira de refluxo (32, 121, 122) a partir da qual fluido é administrado para um paciente. a pressão interna do fluido do acoplador (35) é determinada por um dispositivo de sensoriamento de pressão (38), ou dispositivos que fornecem sinais para os controladores (35, 52,54) que, com base no mínimo nos sinais dos sensores fazem com que os acionadores (22,23,48,50) operem em direções inversa e direta, de modo a diminuir rapidamente e aumentar a pressão de fluido dentro do acoplador (35) durante um revezamento de uma seringa vazia para uma seringa cheia, evitando com isto formação de bolus e uma interrupção na terapia de infusão. bombas de seringa (44, 46) operáveis de maneira independente são consideradas para serem conectadas em maneira de revezamento para formar um sistema modular.
Patent BR-PI0820175-B8 (BR)
Title: uso de oligossacarídeos contendo n-acetillactosamina para maturação de respostas imunes em neonatos.
Inventor: MARIE-CLAIRE FICHOT
IPC: A61P37/08
Filed: 2008-11-07
Abstract: USO DE OLIGOSSACARÍDEOS CONTENDO N-ACETILLACTOSAMINA PARA MATURAÇÃO DE RESPOSTAS IMUNES EM NEONATOS.  A presente invenção refere-se ao uso de um oligossacarídeo selecionado a partir do grupo que consiste em lacto-N-tetraose, lacto-N- neotetraose, lacto-N-hexaose, lacto-N-neoexaose, para-lacto-N-hexaose, para -lacto-N-neoexaose, lacto-N-octaose, lacto-N -neo-octaose, iso-lacto-N- octaose, para-lacto-N-octaose e lacto-N-decaoseína na fabricação de um medicamento para crianças ou uma composição nutricional terapêutica para crianças para modular respostas imunes em uma criança neonatal. A invenção estende-se ao uso de um tal oligossacarídeo para modular o sistema imune de uma criança neonatal para promover o desenvolvimento nas primeiras semanas da vida da criança de um microbiota intestinal benéfico comparável àquele encontrado em crianças alimentadas no peito e para reduzir o risco de desenvolvimento subsequente de alergia na criança.
Patent BR-PI0909267-B8 (BR)
Title: composição farmacêutica e processo para a preparação de uma composição farmacêutica
Inventor: KATHRYN JANE HILL
IPC: C07D235/06
Filed: 2009-03-26
Abstract: composição farmacêutica, processo para a preparação de uma composição farmacêutica, e, métodos para tratar um anilam de sangue quente que sofre de uma condição e para tratar o câncer em um animal de sangue quente a invenção diz respeito às composições farmacêuticas que contém um sal de hidrogeno sulfato de (2-hidróxi-etóxi)-amida do ácido 6-(4-bromo-2-cloro-fenilamino)-7-fluoro-3-metil-3h-benzoimidazol-5-carboxílico e solvatos, formas cristalinas e formas amorfas deste, para uso das ditas composições como um medicamento; e aos processos para a preparação das ditas composições.
Patent BR-PI0917621-B8 (BR)
Title: sistema de injeção de uma matéria termoplástica no estado fluido em uma cavidade de moldagem e seu processo de fabricação e dispositivo de comando de deslizamento
Inventor: ERIC DERICHE
IPC: B29C45/28
Filed: 2009-12-07
Abstract: sistema de injeção de uma matéria termoplástica no estado fluido em uma cavidade de moldagem e seu processo de fabricação e dispositivo de comando de deslizamento a presente invenção trata de um sistema de injeção de matéria termoplástica em uma cavidade de moldagem, e de um processo de fabricação desse sistema. o sistema de injeção de uma matéria termoplástica no estado fluido em uma cavidade de moldagem, compreende: um distribuidor (200) próprio para ser mantido a uma temperatura de injeção superior à temperatura limite além da qual a matéria se apresenta no estado fluido, e o distribuidor compreende um canal de distribuição e pelo menos uma saída de matéria termoplástica, um bico de injeção que define pelo menos uma porção de uma passagem de trânsito, cuja entrada está em ligação fluídica com a saída do canal de distribuição, e cuja saída desemboca sensivelmente na cavidade de moldagem, um obturador (7) montado no interior da passagem de trânsito para deslizar entre a posição de fechamento e uma posição de abertura dessa passagem, meios de comando para fazer deslizar alternadamente o obturador (7), que compreende um macaco (100) cuja haste é paralela à direção (x) de deslizamento do obturador (7) e uma alavanca disposta de modo a se inclinar em torno de um eixo (4) de modo a transmitir ao obturador (7) os movimentos da haste do macaco; em que o macaco é fixado de modo deslocado em relação ao distribuidor (200) por meio de uma viga achatada.
Patent AU-2001240636-B8 (AU)
Title: Use of IL-18 inhibitors
Inventor: KIM SOO-HYUN
IPC: A61K39/00
Filed: 2001-02-20
Granted: 2005-11-03
Abstract: The invention relates to the use of inhibitors of IL-18 in the preparation of a medicament for treatment and/or prevention of liver injury. The invention further relates to the use of IL-18 inhibitors in the preparation of a medicament for treatment and/or prevention of arthritis, in particular rheumatoid arthritis. In addition to this, the invention relates to the use of inhibitors of IL-18 in the preparation of a medicament for treatment and/or prevention of inflammatory bowel diseases, in particular of Crohn's disease and ulcerative colitis.
Patent AU-2003239287-B8 (AU)
Title: Process for the production of strongly adherent coatings
Inventor: BAUER MICHAEL
IPC: C08J7/04
Filed: 2003-01-27
Granted: 2003-09-02
Abstract: A process for the production of strongly adherent coatings on an inorganic or organic substrate is provided, wherein in a first step a) a low temperature plasma, a corona discharge or a flame is caused to act on the inorganic or organic substrate, in a second step b) one or more photoinitiators or mixtures of photoinitiators with monomers, containing at least one ethylenically unsaturated group, or solutions, suspensions or emulsions of the afore-mentioned substances, are applied at normal pressure to the inorganic or organic substrate, in a third step c) using suitable methods those afore-mentioned substances are dried and irradiated with electromagnetic waves and, optionally, in a fourth step d1) the substrate so pretreated is provided with a coating and the coating is cured or dried.
Patent BR-102014006335-B8 (BR)
Title: Método para produzir uma população isolada de células-tronco de polpa dentária imaturas (idpscs) e uso
Inventor: KERKIS IRINA
IPC: A61Q7/00
Filed: 2014-03-17
Abstract: células-tronco de polpa dentária imaturas multifuncionais e aplicações terapêuticas. a presente invenção é direcionada para as células-tronco de polpa dentária imaturas multifuncionais terapêuticas (idpscs) e composições de linhagem múltipla de idpscs. a invenção é adicionalmente direcionada para o uso das idpscs e composições para reduzir o risco de e/ou tratar doenças degenerativas ou para outros fins medicinais e estéticos.
Patent BR-112013010050-B8 (BR)
Title: dispositivo de iontoforese ocular para administrar qualquer solução medicamentosa ionizada
Inventor: EDOARDO STAGNI
IPC: A61N1/32
Filed: 2011-01-12
Abstract: dispositivo e método para liberação córnea de riboflavina por iontoforese para o tratamento de ceratocone, compreende um dispositivo de iontoforese ocular para liberação de qualquer solução de medicamento ionizado, como solução de riboflavina, para a córnea compreende, em combinação: um reservatório (8) contendo uma solução de riboflavina que é adequada para ser meramente posicionada no olho; um eletrodo ativo (2) disposto sobre ou no reservatório (8) ; e um eletrodo passivo adequado para ser posicionado na pele do individuo, ou em outro local do corpo, de preferência em locais próximos ao olho, como na testa, bochecha ou pescoço; meios (10) para irradiação da superfície da córnea com luz adequada, tal como luz uv, para obtenção de ligação cruzada da córnea após a liberação do medicamento ou de riboflavina; onde o referido reservatório (8) e o referido eletrodo ativo (2) são transparentes à luz uv e/ou luz ir; método para liberação de qualquer solução medicamentosa ionizada, tal como solução de riboflavina, para a córnea para tratamento de ceratocome ou qualquer outra doença ectásica da córnea, ou para reforço da estrutura do estroma da córnea por meio de um dispositivo de iontoforese ocular de acordo com as reivindicações precedentes, apresentando as seguintes etapas: - posicionamento do referido dispositivo iontoforético no olho a ser tratado, o dispositivo compreendendo um reservatório contendo a solução de riboflavina: - direcionamento do movimento da solução por uma corrente catódica aplicada durante 0,5 a 5 minutos, a uma intensidade menor que 2 ma; - irradiação, imediatamente após o fim da aplicação atual, da superfície da córnea com uma luz uv durante 5 a 30 minutos a uma potência de 3 a 30 mw/cm2, obtendo, portanto, a ligação cruzada da córnea da riboflavina.
Patent EA-029089-B9 (EA)
Title: Modulators of methyl modifying enzymes, compositions and uses thereof
Inventor: ALBRECHT BRIAN K
IPC: C07D471/04
Filed: 2014-02-11
Abstract: The present invention relates to agents for modulating a methyl modifying enzyme, having the structural Formula (II)and pharmaceutically acceptable salts thereof. Furthermore, the present invention provided a pharmaceutical composition for the use thereof and uses thereof for treating cancer.
Patent AU-2011100018-B9 (AU)
Title: Barrier
Inventor: JAMES MAWBY DANIEL
IPC: E04H17/14
Filed: 2011-01-05
Granted: 2011-11-03
Abstract: A barrier fence 218 for use in bounding horse racing tracks and in like applications is provided. The fence comprises an elongate rail 219 and uprights 220 secured thereto at positions along the rail, wherein: a said upright is secured at an upper end thereof to the rail and at a lower end thereof to a ground anchor 201 that is secured to a ground mass. A bottom fitting 205 at the upright's lower end is separable from the ground anchor in response to an impact load applied to the upright and having a component in either of two mutually opposed directions that are parallel to the rail. In horse racing applications for example, this facilitates provision of a barrier fence that can respond to impacts in essentially the same way irrespective of which of two possible directions along the barrier fence racing takes place.
Patent DE-102017012198-B9 (DE)
Title: Bogentransportvorrichtung und Verfahren zum Transportieren von Bogen von einem Bogenführungszylinder an ein Bogenfördersystem
Inventor: KESSLER VOLKER
IPC: B65H29/32
Filed: 2017-10-13
Granted: 2022-10-06
Abstract: Bogentransportvorrichtung für eine bogenverarbeitende Maschine mit einem Bogen von einem Bogenführungszylinder (2) übernehmenden Bogenfördersystem (3, 4),mit einer Greifeinrichtung (3) zum klemmenden Fixieren und Transportieren einer jeweiligen Bogenvorderkante undmit mindestens zwei den Bogen gleichzeitig an der Zylindermantelfläche des Bogenführungszylinders (2) haltenden umlaufenden Bogenstützsegmenten (6) und pneumatischen Fixiereinrichtungen (10) für die Bogenhinterkante,dadurch gekennzeichnet,dass die Fixiereinrichtungen (10) mit einem Drucklufterzeuger in pneumatischer Verbindung stehen, wobei der Drucklufterzeuger mit genau vier Fixiereinrichtungen (10) einer doppeltgroßen Kettenradwelle (4) in pneumatischer Strömungsverbindung steht.
Patent DE-3205452-C1 (DE)
Title: Device for in situ washing of a packing usable for biological waste water treatment
Inventor: GRABOWSKI GUNTHER
IPC: C02F3/04
Filed: 1982-02-16
Granted: 1983-10-27
Abstract: Trickle filters having a packing of rock chips serve for biological waste water treatment and, when they are designed and charged according to known guidelines, have a so-called self-cleaning capacity, which permits the continuous operation required in sewage treatment plants. However, owing to natural weathering of the stone chips, and also owing to the fine sands carried by the waste water, after a relatively long operating time, deposits occur in the packing which greatly reduce the permeability and thus lead to a reduction in the purification efficiency. As an effective, but also highly expensive method for recovering the permeability, the occasionally practised emptying of the packing, batchwise washing and refilling of the trickle filters can be considered. The invention proposes, by means of the stationary installation of perforated or slotted washing tubes, which are introduced vertically into the packing and are connected to a washing water supply, to wash the packing over the entire filling depth and within a defined region of action in such a manner that all the deposits present in the interstitial spaces between the chips packing are washed out.
Patent DE-3313254-C1 (DE)
IPC: H01H3/38
Filed: 1983-04-13
Granted: 1984-06-28
Abstract: 1. A drive system for electric two-position breakers in medium and high voltage switching installations with repeated deflections of the operating shaft by articulated connections, one of which is designed as a rotary pivot joint (10-16) characterised by the combination of the rotary pivot joint (10 to 16) allotted to the switch (3) with non-linear course for the moment of rotation and angular velocity depending on the angle of rotation, and at least one further angled joint (18 to 24) which is arranged between the first joint and the operating element (8) and is connected to the first joint by means of a coupling shaft (7), and which has a non-linear course for the moment of rotation in dependence on the angle of rotation, in such a mutual assignment of the two angle joints that, in that region of the angle of rotation in which the rotary pivot joint (10 to 16) reaches its minimum moment of rotation, the further angle joints (18 to 24) pass through the maximum value of their moment of rotation.
Patent DE-3408263-C1 (DE)
Title: Process for the production of high-energy-laser mirrors
Inventor: PROTZ RUDOLF DIPL-PHYS DR
IPC: H01S3/034
Filed: 1984-03-07
Granted: 1985-12-05
Abstract: The invention relates to a process for production of high-energy-laser mirrors having a cooling system in composite construction from monocrystalline silicon and glass, in which a finely structured system of cooling channels is etched into the underside of the mirror sheet by electrochemical etching and is fed through holes in the mirror base sheet, and the two sheets are firmly connected to one another by anodic bonding.
Patent DE-3423934-C1 (DE)
Title: Apparatus for preventing the overlaying of piglets in piglet breeding farms and its use as a display device for the start of the farrowing process in sows
Inventor: DE WIT PAULUS ALPHENSUS JOSEPH
IPC: A61D17/00
Filed: 1984-06-29
Granted: 1985-08-29
Abstract: The invention relates to an apparatus for preventing the overlaying of piglets in piglet breeding farms, with at least one microphone assigned to a farrowing pen accommodating the sow and the piglets, a sound detector connected to the microphone which triggers an electrical pulse as a function of the stored sound signal serving as a comparison signal, and a warning installation which can be actuated by the pulse triggered by the noise detector. This apparatus can be used as a display device for the start of the farrowing process in sows.
Patent DE-3609883-C1 (DE)
Title: Tack for sheet-metal roofs
Inventor: SCHOOP TRAUGOTT
IPC: E04D3/361
Filed: 1986-03-24
Granted: 1987-09-17
Abstract: Tack, in particular sliding tack, for retaining the metal sheets of double-fold sheet-metal roofs on substructures. The tack has a horizontal fastening leg (11) and a retaining leg (17) which projects away perpendicularly therefrom. In the region of the bend edge (15) between the two legs (11, 17), at least one fastening hole (23) is arranged beneath the retaining leg (17). As a result, wind forces (suction) are channelled perpendicularly into the substructure from the sheet-metal roof via the retaining leg (17) and via a fastening means arranged in the fastening hole (23). <IMAGE>
Patent DE-3610864-C1 (DE)
Inventor: SCHUER KARL-HEINZ
IPC: B65D55/02
Filed: 1986-04-01
Granted: 1987-04-09
Abstract: 1. Twist-off cover for container, comprising a screw cap (1) and a sealing device which fixes the screwed-down cover by means of a plastics ratchet ring (9) on the flange against being twisted off and which releases the cover only on account of a recognizable change thereat, wherein the cover (1) seated on the flange is wedged between the cover and the foot of the flange, characterised in that the ratchet ring (9) is joined by means of plastics film joints (17) to concentric retaining ring portions (15) which surround the cover (1) concentrically, wherein the cover (1) is provided with locking elements (7) that project outwardly and have cutting edges (31) which between the ratchet ring (9) and the retaining ring portions (15) are directed circumferentially towards the plastics film joint (17).
Patent DE-3714826-C1 (DE)
Title: Shuttleless weaving machine with a pneumatic weft-insertion device consisting of a main nozzle and of a downstream mixing tube
Inventor: WAHHOUD ADNAN DIPL-ING
IPC: D03D47/36
Filed: 1987-05-04
Granted: 1988-06-01
Abstract: The invention relates to a pneumatic weaving machine with a main nozzle and with relay nozzles distributed over the weaving width, the weft thread being drawn off from stock bobbins upstream of the respective weft insertion, being metered in a predetermined length and being stored intermediately in a thread store. A special drawing-off device serves for drawing off the thread from the thread store and feeds the thread to the main nozzle in a tension-free manner. The drawing-off device advantageously consists of a pair of conveying rollers which can be driven in a controlled manner and which are pressed together at a point on their circumference for the thread transport and positively transport the thread clamped between them. The main nozzle needs to bring the thread only up to the guide channel in the region of the first relay nozzle, whereupon the relay nozzles take over the further transport over the weaving width. The arrangement results in a considerable reduction in the air pressure and also in the air consumption. <IMAGE>