baber/WOPTO huggingface dataset:
Patent NZ-604125-A (NZ)
Title: Prediction of hcv viral kinetics in interferon-free treatment
Inventor: SHULMAN NANCY
IPC: A61K31/7052
Filed: 2011-08-03
Abstract: Disclosed is a method for predicting early viral load reduction of a human subject infected with HCV to interferon-free treatment that comprises at least one direct acting antiviral agent, comprising: providing a sample from said human subject and identifying the nucleotide present at single nucleotide polymorphism rs12979860, wherein the presence of two C alleles at rs12979860 in said subject indicates a higher likelihood of early viral load reduction from said interferon-free treatment relative to a subject without two C alleles present at rs12979860.
Patent NZ-610700-A (NZ)
Title: Derivatives of heteroarylsulfonamides, their preparation and their application in human therapy
Inventor: DUPONT-PASSELAIGUE ELISABETH
IPC: C07D417/12
Filed: 2011-11-23
Abstract: Provided are heteroarylsulfonamide derivative compounds, of the general formula I, where the variables are as defined in the specification. Two examples of the compounds are N-(2-(4-(6-fluorobenzo[d]oxazol-2-yl)piperazine-1-carbonyl)phenyl)-5-(trifluoromethyl)pyridine-2-sulfonamide and N-(2-(4-(6-(trifluoromethoxy)benzo[d]thiazol-2-yl)piperazine-1-carbonyl)-phenyl)quinoline-8-sulfonamide. Further provided are methods of preparing the compounds and pharmaceutical compositions comprising them. The compounds block Kv (voltage gated potassium) channels and may be useful in the treatment of cardiovascular disorders, particularly atrial fibrillation, chronic inflammation and cancer.
Patent NZ-610788-A (NZ)
Title: Process for isolating fucoidan and laminarin from live, harvested seaweed
Inventor: HJELLAND FINN
IPC: C12R1/89
Filed: 2011-11-18
Abstract: Disclosed is a process for obtaining at least one of fucoidan and laminarin from live, harvested seaweed, wherein said process comprises the steps of: , (i) harvesting seaweed comprising fucoidan and laminarin to obtain said live, harvested seaweed, wherein said live, harvested seaweed exudes to form an exudate solution; , (ii) collecting said exudate solution after two days of exudation, wherein said fucoidan and laminarin are dissolved in said exudate solution; and, (iii) separating said at least one of fucoidan or laminarin from said exudate solution.
Patent NZ-611110-A (NZ)
Title: Childcare device including inflatable safety elements
Inventor: RENAUDIN François
IPC: B60N2/28
Filed: 2011-12-20
Abstract: The disclosure relates to a childcare device capable of accommodating a child, including a harness (12) having two straps (121, 122) intended to extend from the shoulders along the torso of a child, each strap having an inflatable safety element (141, 142) capable of inflating in the event of an impact greater than a predetermined threshold. The device comprises means for reversibly attaching the inflatable safety elements together.
Patent NZ-619009-A (NZ)
Title: Medicaments and methods for treating cancer
Inventor: SHESHBARADARAN HOOSHMAND
IPC: C01G55/00
Filed: 2012-05-17
Abstract: Provided are compositions comprising sodium trans-[tetrachlorobis(1H-indazole)ruthenate (III)], and uses of these in the treatment of cancer. The compositions involve the delivery of 400-1562.5 mg or 320-625 mg/m2 of the compound based on the body surface area of the patient, and contain a reduced amount of indazolium hydrochloride. The dosage range is based on the minimum effective dose and maximal tolerated dose of the compound. Further provided is the use of the compound in the treatment of cancer by particular administration schedules, and with the administration of a drug to prevent infusional fever which can be a side effect of intravenous sodium trans-[tetrachlorobis(1H-indazole)ruthenate (III)] administration.
Patent NZ-621347-A (NZ)
Title: Embodiments of a probe and method for targeting nucleic acids
Inventor: HRDLICKA PATRICK J
IPC: C07H19/00
Filed: 2012-07-19
Abstract: The disclosure relates to a double stranded probe comprising a pair of monomers of the general formula as shown in the abstract figure and at least one nucleotide. The pair of monomers may be arranged in a manner that promotes thermoinstability of the probe complex, thus producing a probe capable of locating and/or detecting a target. The probe also may comprise one or more natural or non-natural nucleotides capable of Watson-Crick base pairing with an isosequential nucleic acid target. Particular disclosed embodiments concern a method of using the disclosed probe to target nucleic acids. In particular disclosed embodiments, the probe may be incubated with a target nucleic acid and then be detected.
Patent NZ-626379-A (NZ)
Title: Pharmaceutical preparation comprising brexpiprazole and substituted beta - cyclodextrin
Inventor: TOYOBUKU HIDEKAZU
IPC: A61K47/48
Filed: 2012-12-28
Abstract: Provided is an aqueous pharmaceutical preparation comprising 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one (brezpiprazole) or a salt thereof, which shows improved water solubility of compound (I) or a salt thereof achieved by addition of substituted β -cyclodextrin. The present disclosure provides a pharmaceutical preparation comprising compound (I) or a salt thereof, and substituted β-cyclodextrin. The pharmaceutical compositions are useful in the treatment of neurological diseases.
Patent NZ-628686-A (NZ)
Title: Compositions comprising sphingosine 1 phosphate (s1p) receptor modulators
Inventor: RUEGGER COLLEEN
IPC: A61K47/00
Filed: 2008-10-09
Abstract: Discloses herein is a stable binary blend of a pharmaceutical composition for oral administration, which comprises: (i) a compound selected from 2-amino-2-[2-(4-octylphenyl) ethyl]propane-1,3-diol (FTY720) in free form, a pharmaceutically acceptable salt thereof, FTY720-phosphate, 1-{ 4-[1-(4-cyclohexyl-3-trifluoromethyl-benzyloxyimino)-ethyl]-2-ethyl-benzyl} -azetidine-3-carboxylix acid, and (ii) one excipient selected from the group consisting of: Lactose, Hydroxypropyl methylcellulose (HPMC), Hydroxypropylcellulose (HPC), Crospovidone, Croscarmellose sodium, starch, and Colloidal silicone dioxide; the blend may optionally comprise further ingredients selected from: (b) Binders selected from HPMC, L-HPC, povidone, HPC, (c) Disintegrants selected from maize starch, crospovidone, croscarmellose sodium, sodium carboxymethylstarch, pregelatinized starch, calcium silicate, (d) Lubricants selected from hydrogenated castor oil, glycerol behenate, magnesium stearate, calcium stearate, zinc stearate, mineral oil, silicone fluid, sodium lauryl sulfate, L- leucine, sodium stearyl fumarate, (e) Flow regulators selected from colloidal silicone dioxide, talc, (f) Matrix formers selected from hydroxypropyl methyl cellulose, hydroxypropyl cellulose, methyl cellulose, ethyl cellulose, pullulan, starch, povidone, (g) Plastisizers selected from PEG 400, Dibutyl sebacate, sorbitol, (h) Flavoring agents selected from menthol, tutti fruit, and (i) Sweeteners selected from sucralose, sodium saccharine.
Patent NZ-703463-A (NZ)
Title: Satellite navigation signal, generating method, generating device, receiving method and receiving device
Inventor: YAO ZHENG
IPC: H04L27/26
Filed: 2013-06-06
Abstract: Provided are a satellite navigation signal and a generation method, generation device, receiving method and receiving device for a satellite navigation signal. The satellite navigation signal generation device comprises a baseband signal generator, a multiplexing signal generator and a modulator. The baseband signal generator generates a first baseband signal S1, a second baseband signal S2, a third baseband signal S3 and a fourth baseband signal S4. The multiplexing signal generator sets the amplitudes and phases of in-phase baseband components and quadrature baseband components of a multiplexing signal of the first baseband signal S1, the second baseband signal S2, the third baseband signal S3 and the fourth baseband signal S4, so as to generate a multiplexing signal having a constant envelope. The modulator modulates the multiplexing signal having the constant envelope to a radio frequency to generate a satellite navigation signal. The first baseband signal S1 and the second baseband signal S2 are modulated at a first carrier frequency fand their carrier phases are orthogonal to each other, and the third baseband signal and the fourth baseband signal are modulated at a second carrier frequency and their carrier phases are orthogonal to each other.
Patent NZ-720148-A (NZ)
Title: Emulsions or microemulsions for use in endoscopic mucosal resectioning and/or endoscopic submucosal dissection.
Inventor: REPICI ALESSANDRO
IPC: A61L24/00
Filed: 2014-11-18
Abstract: The invention provides a pharmaceutical composition in form of emulsion or microemulsion for use in an endoscopic procedure, said endoscopic procedure preferably comprising the administration of said pharmaceutical composition to a human. The invention herein disclosed provides a method for performing an endoscopic procedure, said method preferably comprising the administration of a pharmaceutical composition in form of emulsion or microemulsion to a human.
Patent NZ-723142-A (NZ)
Title: Automated on demand baking system
Inventor: MARCO DORON
IPC: A23C3/00
Filed: 2015-02-17
Abstract: An automated, on-demand baking system including a computer controllable injector configured to be operative to programmably inject liquid baking ingredients through a wall of and into a mixing, baking and dispensing container, a computer controllable rotator configured to be operative to programmably rotate the mixing, baking and dispensing container containing baking ingredients, thereby mixing the baking ingredients into a dough, a heating generator operative to cause baking of the dough in the mixing, baking and dispensing container and a controller operative to govern the operation of the computer controllable injector, the computer controllable rotator and the heating generator.
Patent NZ-747853-A (NZ)
Title: Method for preparation of ammonium polyvanadate with high-concentration vanadium solution
Inventor: GUO JIKE
IPC: C01G31/02
Filed: 2017-07-12
Abstract: The invention relates to the field of chemical industry, and particularly to a method for preparation of ammonium polyvanadate with high-concentration vanadium solution. In view of the problems of the prior art, including that vanadium precipitation can be only conducted with low-concentration vanadium solution, the process is long and the production cost is high, the invention provides a method for vanadium precipitation with high-concentration vanadium solution of low cost and high efficiency. In the method, high-concentration vanadium solution is adjusted to proper temperature and pH value, ammonium salt is added, and the mixture is then slowly added into the solution with vanadium-containing powder for reaction. Ammonium polyvanadate can be obtained after the reaction. The technical scheme of the invention effectively solves the problem of vanadium precipitation with high-concentration vanadium solution and can improve the content of TV in vanadium solution for vanadium precipitation to 40–110g/L. The invention has simple processes, high vanadium precipitation rate and low content of impurities in product. Compared with the existing process of vanadium precipitation with acidic ammonium salt, the method can reduce the quantity of wastewater after vanadium precipitation by over 50% for each ton of V2O5 produced, thus significantly improving the operation efficiency and reducing the production cost.
Patent NZ-749330-A (NZ)
Title: Improvements in and relating to road safety rail systems and parts and fittings therefor
Inventor: ANDREW KARL DIEHL
IPC: E01F15/04
Filed: 2018-12-19
Abstract: A road safety rail system comprising at least one continuous rail, or a plurality of sequentially connected system rails, forming a main body of a barrier, which are supported above ground by one or more ground engaging posts, wherein the system also comprises a terminal end section (TES) having an upstream end and a downstream end, the TES including: a stationary component a moving energy absorbing component comprising an impact head including a base and upright projection, the base comprising an axial orifice extending from a downstream entry point to an upstream exit point, through which an upstream terminus of an FTE rail is passed before the FTE rail is directly or indirectly connected to a releasable connection point coupled to a ground anchor; wherein the impact head is connected via at least one beam to a post detacher element located downstream of said impact head a pre-determined distance therefrom. Wherein the road safety rail system addresses issues with terminal ends which can include: - Complicated construction requiring modification (e.g. removing material) from a large number of rails over a long distance, which is labour intensive, time consuming and expensive; - Potential instability of the constricting head; - Difficulties transitioning the rail from an above ground height down to ground level; - Requiring tensioned cables; - Complicated head designs to deform the rail in one or more dimensions; - Creating hazards for vehicles which detract from any energy absorbing capability of the terminal end including but not limited to creating a potential ramp for an impacting vehicle; - The potential for the rail to buckle and fail to adequately and/or safely absorb energy; or Wherein the road safety system of the present invention provides the public with a useful choice.
Patent NZ-751555-A (NZ)
Title: C1-inh compositions and methods for the prevention and treatment of disorders associated with c1 esterase inhibitor deficiency
Inventor: GALLAGHER CYNTHIA
IPC: A61K38/55
Filed: 2014-03-17
Abstract: Lyophilised compositions and methods for the treatment and/or prevention of disorders associated with C1 esterase inhibitor deficiency, such as hereditary angioedema (HAE), via subcutaneous administration, wherein the lyophilised compositions when reconstituted comprise a C1 esterase inhibitor between 400 to 600 U/mL, a sodium citrate buffer, a pH in the range of 6.5 to 8.
Patent NZ-759817-A (NZ)
Title: Cold brew coffee beverage and method of making the same
Inventor: GELOV TEODOR
IPC: B01D35/30
Filed: 2017-11-03
Abstract: Disclosed are processes for making cold brew beverage compositions including concentrates and apparatus for preparing cold brew beverage compositions. The disclosed processes and apparatus allow for efficient, rapid, industrial scale production of cold brew beverage compositions having improved total solid content, improved flavor stability, longer shelf-life, and adaptability to use in small volume containers.
Patent PT-115021-A (PT)
Title: Dispositivo para despiste da presença ou ausência do antigénio de superfície do vírus da hepatite b
Inventor: FERNANDO JOSÉ FIGUEIREDO AGOSTINHO D'ABREU MENDES
IPC: C12Q1/25
Filed: 2018-09-07
Abstract: A PRESENTE INVENÇÃO REFERE-SE A UM DISPOSITIVO QUE PERMITE, DE FORMA SIMPLES, RÁPIDA E ECONÓMICA, REALIZAR O DESPISTE DA PRESENÇA OU AUSÊNCIA DO ANTIGÉNIO DE SUPERFÍCIE DO VÍRUS DA HEPATITE B EM AMOSTRAS BIOLÓGICAS, NOMEADAMENTE ATRAVÉS DA SALIVA. O DISPOSITIVO DE DESPISTE CONSISTE NUM INVÓLUCRO (5) O QUAL CONTEM UM ELEMENTO RECETOR DE SALIVA (1) E UMA CÂMARA DE LEITURA (2), PARA LEITURA E INTERPRETAÇÃO DOS RESULTADOS, DIVIDIDA NUM CAMPO DE CONTROLO (3) E NUM CAMPO DE RESULTADO (4). A SALIVA É DEPOSITADA NO ELEMENTO RECETOR (1) SOBRE UMA TIRA QUÍMICA QUE NO CASO DE PRESENÇA DO ANTIGÉNIO DE SUPERFÍCIE DO VÍRUS DA HEPATITE B REAGE FORMANDO IMUNOCOMPLEXOS, SENDO POSSÍVEL A INTERPRETAÇÃO DOS RESULTADOS PELO SURGIMENTO DE UMA BANDA DE COR.
Patent RU-94019605-A (RU)
Inventor: AKSENOV N I
IPC: B66F11/04
Filed: 1994-05-25
Abstract: FIELD: hoisting facilities for operation at tall structures in fire fighting, people rescue work, etc. SUBSTANCE: device has additional cradle 23 capable of vertical displacement in space by means of ropes attached to it and reeving through pulleys mounted on one of section such as main section 11. Main working cradle 15 and additional one 23 are provided with coupling units for coupling and connection to each other in space at corresponding folding of intermediate sections 12, 13 and last section 14. EFFECT: improved efficiency. 7 dwg
Patent RU-94024287-A (RU)
Inventor: KAZANTSEV G F
IPC: C22B15/00
Filed: 1994-06-29
Abstract: FIELD: nonferrous metallurgy. SUBSTANCE: cadmium oxide in amount of 2-6 % is dissolved in melt and process is carried out at cathode current density equal to 0.2-1.5 A/cmand anode current density of 0.25-1.9 A/cm. Use is made of indifferent anode and liquid or indifferent solid cathode at interpole distance of 2-5 cm. EFFECT: increased capacity, cut down capital outlays, enhanced ecological situation at electrolysis of alkaline-carbonate melt.
Patent RU-94027091-A (RU)
Inventor: JURLIN L A
IPC: A61B5/00
Filed: 1994-07-29
Abstract: FIELD: medicine. SUBSTANCE: method involves evaluating sympathico- parasympathic balance index (SPBI) value from R-R interval distribution as ratio of two parameters: mode amplitude (MA) to number of positions (N) forming the distribution. Logarithmic scale is used. R-R interval estimate resolution capacity is defined to be equal to 0.01 s. Positive value and magnitude of the SPBI determine domination and domination measure of sympathic component of organism cardiovascular system, respectively. Negative value and magnitude of the SPBI determine domination and domination measure of parasympathic component of organism cardiovascular system, respectively. R-R interval distribution median frequency (F, Hz) is evaluated. A patient is identified with respect to his individually typological cardiovascular activity specific features by means of two-dimensional plane vector coordinates, where SPBI is the ordinate (conditional units, logarithmic scale), and apex is the R-R interval distribution median frequency (Hz) in (100x5) cardiocycles. Attention distribution level evaluation is carried out by means of modified version of known methods united under the common name of "correction tests". Cardiovascular activity types of an organism are set in correspondence to different time-and- space distributions of human attention in response to stimulation with six-to-eight alternatives. EFFECT: unbiased evaluation of human attention properties.
Patent RU-94027668-A (RU)
Inventor: KOLETVINOVA T V
IPC: H03K5/13
Filed: 1994-07-21
Abstract: FIELD: computer engineering, control devices for information processing. SUBSTANCE: device has OR gate 1, AND gate 2, control counter 3, OR gate 4, commutator 5, memory unit 6, delay line 7, AND gate 8, control flip-flops 9 and 10, OR gate 14, (N+3) AND gates 15, N output JK flip-flops. Introduced commutator 5, control flip-flop 9, OR gate 4 first and second AND gates 2 and 8 result in possibility of storage new data codes to memory unit 6 when device operates. Introduced control flip-flop 10, AND gate 11, shift register 12, AND gate 13 and OR gate 14 provide possibility of delay between edges of output signals. EFFECT: possibility of data change when device operates. 2 dwg
Patent RU-94028810-A (RU)
Inventor: KOZLOV D V
IPC: G01N33/48
Filed: 1994-08-01
Abstract: FIELD: medicine, oncology. SUBSTANCE: method is based on tumor parenchyma and stroma staining. Method involves immunohistochemical detection by point system using antibodies against α-macroglobulin and α-glycoprotein associated with gestation. Positive effect of radiation therapy is estimated as positive at decrease of macroglobulin detection in tumor tissue parenchyma to 2.75 ± 0.12 and less and at increase in stroma to 2.61 + 0.11 and above, and decrease of glycoprotein detection in parenchyma and stroma to 3.11 + 0.12 and 2.89 + 0.12 and less, respectively. Insufficient effect of radiation therapy is estimated at macroglobulin value detection in parenchyma 2.75 + 0.12 and above, and in stroma - 2.61 + 0.11 and less, and at glycoprotein detection in parenchyma and stroma 3.11 + 0.12 and 2.89 + 0.12 and above, respectively. EFFECT: improved method of radiation therapy estimation.
Patent RU-94028843-A (RU)
Title: Line for processing gold-containing ores
Inventor: PETUKHOVA S N
IPC: C22B3/02
Filed: 1994-08-02
Abstract: FIELD: hydrometallurgy of noble metals, namely, gold recovery from ores by cyaniding, for example, at processing ores with non-industrial content of gold. SUBSTANCE: line comprises mounted according to technological process and mutually connected by transportation means disintegrating module, module for dewatering of disintegrated products, module for sorption cyaniding of concentrated products, module for desorption of gold from saturated sorbent, module for regeneration of sorbent, module for demetallization of gold-containing solutions and tailings dump jointed with module for sorption cyaniding by means of transporting clarified liquid phase for percolation leaching and by means for transporting solutions of percolation leaching with the module for sorption cyaniding and/or the module for disintegration. EFFECT: enlarged functional possibilities of the line due to provision of processing lean ores by their percolation leaching in separate cycle by clarified solution of tailing pulp and processing of productive solution of percolation leaching in common cycle.
Patent RU-94034542-A (RU)
Inventor: KHASANOV I JU
IPC: F16L55/105
Filed: 1994-10-03
Abstract: FIELD: pipe line engineering. SUBSTANCE: device has assembled valving unit which consists of two assembly of sealed telescopic members arranged symmetrically inside the central member. When the telescopic members are extended they form a disk with seals over periphery. The disk is coupled with a drive. The rod of the drive is made up as a shaft-rack the top end of which is provided with actuators for lowering, lifting, and rotating the shaft-rack via clutches made up as gear wheels which wraps the rack around the periphery and conical gear transmission. The bottom end of the shaft-rack is connected with the reduction gear of the drive of movement of the telescopic members through a intermediate clutch. The reduction gear is mounted on the webs rigidly coupled with the central member. The drive is made up as extensible threaded concentric cylinders mounted inside the output shaft of the reduction gear. The outer end faces of the latter cylinders are rigidly coupled with the end telescopic members. The telescopic members are extended one with respect to the other along dovetail guides. At the center of the shaft-rack is the guide cylinder that allows the shutting off device to be locked at a given position with respect to the assembling branch pipe welded in the pipe line. EFFECT: enhanced reliability.
Patent RU-94037245-A (RU)
Inventor: DEHVID V TEHLBOT
IPC: A61F13/00
Filed: 1992-01-17
Abstract: FIELD: band for applying to tissue of human being or animal. SUBSTANCE: band has heat-retaining devices adhering to tissue for reflecting heat from human being's or animal's tissue and back to tissue. Heat-retaining devices are covered with isolating material, which is coated with textile material. Each heat-retaining device has multilayer structure made from first layer of thin film, such as polymeric material, adhering to tissue, second layer of aluminum foil applied to first polymeric layer and connected with it and layer of fiber glass fabric, which covers aluminum foil layer and is connected with it. Additional textile devices may be inserted between heat-retaining devices and human being's or animal's tissue. Heat-retaining and textile devices are joined by stitching or by adhesive material so as to produce pack of heat-retaining means. EFFECT: increased efficiency, wider operational capabilities and enhanced reliability in operation.