baber/WOPTO huggingface dataset:
Patent CA-2961029-A1 (CA)
Inventor: ANNIS DAVID ALLEN
IPC: A61K38/12
Filed: 2015-09-24
Abstract: Aqueous pharmaceutical formulations, for parenteral administration, comprising peptidomimetic macrocycle or a pharmaceutically acceptable salt thereof wherein the peptidomimetic macrocycle binds to MDM2 and/or MDMX proteins are disclosed. Also disclosed are methods of treating diseases and disorders using the aqueous pharmaceutical formulations disclosed herein.
Patent CA-2962444-A1 (CA)
Inventor: MARBAN EDUARDO
IPC: A61K35/34
Filed: 2015-10-02
Abstract: Described herein are compositions and techniques related to generation and therapeutic application of cardiosphere-derived cells (CDCs) and CDC-derived exosomes. These cells and their secreted vesicles contain a unique milieu of biological factors, including cytokines, growth factors, transcription factors, nucleic acids including non-coding nucleic acids such as microRNAs, that serve to initiate and promote many therapeutic effects. Exosomes and their "cargo" contents, such as microRNAs can favorably modulate apoptosis, inflammation and fibrosis in the injured heart. Thus, CDC-derived exosomes represent a novel "cell-free" therapeutic candidate for tissue repair.
Patent CA-2963831-A1 (CA)
Inventor: WEKSBERG ROSANNA
IPC: C12Q1/68
Filed: 2015-08-28
Abstract: The present disclosure provides epigenetic signatures, comprising genomic CpG dinucleotide sequences, genes, and/or genomic regions, which are differentially methylated in individuals with Sotos syndrome relative to non- Sotos syndrome controls, and their use in methods and kits for detecting and/or screening for Sotos syndrome, or the likelihood of Sotos syndrome. The present disclosure also provides epigenetic signatures, comprising genomic CpG dinucleotide sequences, genes, and/or genomic regions, which are differentially methylated in individuals with Weaver syndrome relative to non-Weaver syndrome controls, and their use in methods and kits for detecting and/or screening for Weaver syndrome, or the likelihood of Weaver syndrome.
Patent CA-2965414-A1 (CA)
Title: Variantes de l'interferon .alpha.2.beta.
Inventor: BEHRENS COLLETTE
IPC: A61P39/00
Filed: 2015-10-23
Abstract: La présente invention concerne un polypeptide de fusion comprenant un premier domaine et un second domaine, le premier domaine comprenant un polypeptide ligand qui se lie à un antigène associé à la surface des cellules et le second domaine comprenant l'interféron a 2b aglycosylé (IFNa2b) ayant une séquence de SEQ ID NO : 1 ou SEQ ID NO : 2. L'IFNa2b aglycosylé comprend en outre une ou plusieurs substitutions ou délétions d'acides aminés qui atténuent l'activité de l'IFNa2b aglycosylé.
Patent CA-2969192-A1 (CA)
Title: A process for producing crystals of a diazabicylooctane derivative and a stable lyophilized composition thereof
Inventor: OGAWA TAKAYA
IPC: C07D471/08
Filed: 2015-12-04
Abstract: The purpose of the present invention is to provide a method with which it is possible to easily produce crystals of compound (I) on an industrial scale, and to provide a stable lyophilized composition of said compound (I). It was discovered that a lyophilized composition having exceptional storage stability and in which compound (I) is in crystalline form can be obtained by lyophilizing an aqueous solution that contains said compound (I) and an inorganic salt such as sodium chloride, and that crystals of said compound (I) can be obtained from said aqueous solution even without lyophilization.
Patent CA-2969465-A1 (CA)
Title: Low ph automatic dishwashing detergent composition
Inventor: BROOKER ALAN THOMAS
IPC: C11D17/04
Filed: 2015-12-15
Abstract: Low-pH automatic dishwashing detergent composition having a pH as measured in 1% weight aqueous solution at 25°C of from about 5 to about 7.5 and comprising a protease selected from the group consisting of :(i)a metalloprotease; (ii) a cysteine protease, (iii) an aspartate protease, and mixtures thereof.
Patent CA-2978159-A1 (CA)
Inventor: FATTAH ABDEL RAHMAN ABDEL
IPC: G01N27/327
Filed: 2017-08-31
Abstract: A new magnetic carbon nanotube (mCNT) biosensor ink (mbio-ink) that utilizes immobilized capture agents to detect specific target analytes via a simple current response method is presented here, expanding the applications of magnetic carbon nanotubes as biomolecule-sensing nanomaterials. The employment of a magnetic field to print the mbio-ink into electrically conductive networks facilitates its integration with an external circuit via the use of a simple electrode system. When the sensor is connected to an external power source, the reduction in current, caused by an interaction between the capture agents and target analyte, is detected. The rapid detection technique and generic benchtop fabrication method allows for scale up, while the small volumes required and magnet independent electrical measurements renders the mbio-ink attractive for drug screening and disease detection applications.
Patent CA-2978383-A1 (CA)
Title: Traffic diversion signalling system and method
Inventor: AGARWAL YOGESH
IPC: G08G1/00
Filed: 2016-01-14
Abstract: The present invention provides a traffic diversion system at a traffic intersection which comprises a traffic signal arrangement including a straight-through signal, a stop signal, a custom signal. The traffic diversion system at a traffic intersection further provides for two opposite straight-through signals to open at a time and direct right turn in a left-hand traffic system and a direct left turn in a right-hand traffic system is prohibited. According to an embodiment, the vehicle which intends to take right turn in a left-hand traffic system will be directed using custom signal to take a left turn and a 'U' turn. Similarly, in a right-hand traffic system, the vehicle which intends to take left turn will be directed to take a right turn and a 'U' turn upon the custom signal being enabled
Patent CA-2980185-A1 (CA)
Inventor: ALLISON SYLVESTER
IPC: A63B21/055
Filed: 2017-09-26
Abstract: A combination massage table with one or more resistance bands (hereinafter, a combination table) is disclosed. In some embodiments, the combination table may comprise: a massage table; the one or more resistance bands; and a means for attaching the one or more resistance bands to the massage table; such that a client using the combination table receives at least one improved health benefit as compared against massage therapy without any resistance band use. Furthermore, methods for using the combination table are disclosed. Such methods may comprise: preparing the combination table for use; preparing the client so the client is laying on top of an upper surface of the combination table; and massaging the client while the client at least intermittently engages one or more resistance bands that are attached to the combination table, wherein in the at least intermittent engagement of the one or more resistance bands while the client is being massaged results in the at least one improved health benefit to the client.
Patent CA-2984059-A1 (CA)
Inventor: FONTAINE LOIC
IPC: H04L27/26
Filed: 2016-04-28
Abstract: L'invention concerne des procédés et des appareils pour traiter un signal qui est émis avec un rapport puissance crête sur puissance moyenne réduit. Le traitement consiste à appliquer (1650) une projection d'extension de constellation de symboles à au moins un symbole dans la constellation, la projection d'extension de constellation de symboles comportant une région angulaire extérieure à partir d'une position d'origine pour l'au moins un symbole dans la constellation, la région angulaire extérieure étant définie par une valeur pour un angle entre une première limite et une seconde limite de la région angulaire extérieure, la valeur de l'angle étant déterminée par une sélection de la constellation utilisée comme partie du signal transmis et un rendement de codage utilisé pour coder le flux de données.
Patent CA-2984586-A1 (CA)
Inventor: DING CHARLES Z
IPC: A61K31/5383
Filed: 2016-04-20
Abstract: Disclosed is a fused-ring or tricyclic aryl pyrimidine compound used as a mutation selectivity EGFR inhibitor. Specifically, disclosed is a compound represented by formula (I) and used as an EGFR inhibitor or a pharmaceutically acceptable salt thereof.
Patent CA-2988315-A1 (CA)
Inventor: DING YUCHANG (BOB)
IPC: F04B49/20
Filed: 2017-12-06
Abstract: A submersible, hydraulically actuated, multi-stage double-acting positive displacement pump system is provided. The system has a hydraulically actuated reciprocating linear double-acting motor centrally disposed between and connected to double-action fluid pumps on either side of the motor, with pistons of each of pump and the motor all in the annular space between an inner wall of the apparatus' cylindrical body and the outer wall of a cylindrical production fluid conduit concentrically disposed within the body, to pump wellbore fluid from outside the assembly through the pumps and into the central production fluid conduit. The rate and direction of hydraulic fluid flow through the actuator may be controlled by VFD motors and PLC controller on the ground, and through at least one electromechanical valve and two limit switches mounted to the downhole components.
Patent CA-2990501-A1 (CA)
Inventor: HEITER UWE
IPC: A61F5/34
Filed: 2016-06-20
Abstract: The invention relates to a device (2) for treating carpal tunnel syndrome of a person's hand, which has a palmar aspect, with thenar and hypothenar regions, and a dorsal aspect opposite the palmar aspect. The cuff (1) has a C-shaped profile in cross section, wherein two ends of the C-shaped profile of the cuff (1) form the cuff opening (1a). The cuff (1) is formed from two or more cuff parts (3), wherein these cuff parts (3) have a C-shaped profile in cross section and are connected to each other by means of a connection element (4) to form the cuff (1). The cuff parts (3) are preferably connected to each other, by means of the connection element, in a movable and/or pivotable and also releasable manner, such that the width of the cuff opening (1a) can be individually adapted for each patient. This results in simple, efficient and safe treatment and handling of the cuff (1) according to the invention or of the device (2).
Patent CA-2992548-A1 (CA)
Title: Guide-foret pour elements de fixation de cotyles prothetiques
Inventor: TERMANINI ZAFER
IPC: A61F2/46
Filed: 2016-07-15
Abstract: Lorsqu'un cotyle prothétique utilisé en chirurgie de remplacement de la hanche doit être fixé à l'acétabulum au moyen de vis, les instruments guide-foret de l'invention sont utilisés pour positionner un foret de sorte que les trous de vis forés dans l'acétabulum soient placés correctement pour une implantation optimale du cotyle prothétique. Ledit guide-foret est verrouillé dans le cotyle prothétique par des goupilles à ressort qui positionnent le guide sur les trous dans le cotyle qui logent les vis. Le guide est utilisé pour positionner les forets et permettre le forage. Ledit guide est retiré après le forage.
Patent CA-2994615-A1 (CA)
Inventor: CHOI JIN SOO
IPC: H04N19/51
Filed: 2012-09-14
Abstract: Il est décrit un procédé de génération dun vecteur de mouvement prédit, ainsi quun dispositif utilisant ce procédé. Un procédé de décodage dimage peut comprendre une étape consistant à déterminer linformation relative à une pluralité de vecteurs de mouvement prédits candidats spatiaux à partir de blocs prédits périphériques dun bloc cible prédit, ainsi quune étape consistant à déterminer linformation relative à des vecteurs de mouvement prédits candidats temporels sur la base de linformation relative à la pluralité de vecteurs de mouvement prédits candidats spatiaux. La présente invention permet ainsi de réduire la complexité et daméliorer lefficacité du codage lors de la génération du vecteur de mouvement prédit optimal.
Patent CA-2998810-A1 (CA)
Inventor: BENENATO KERRY E
IPC: C07D277/38
Filed: 2016-09-16
Abstract: The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions further including therapeutic and/or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.
Patent CA-3000517-A1 (CA)
Title: Solar channel letters
Inventor: GOOSEN-IANNI AMANDA A
IPC: H02S20/20
Filed: 2018-04-09
Abstract: An LED sign, either fascia or channel letters that is lit by a combination of thin-film solar panels attached to the tops and sides of the signage whit or without thin-film coloured solar glass application to the faces of the signage itself. Solar batteries either contained within the signage or a close proximity behind installation wall.
Patent CA-3002718-A1 (CA)
Title: Systeme passif de lutte anti-incendie et procede de fabrication
Inventor: LOEWEN ERIC PAUL
IPC: A62C3/06
Filed: 2016-10-13
Abstract: L'invention concerne un système passif de lutte anti-incendie (10) qui est conçu pour éteindre un feu métallique (44). Le système comprend un réservoir (14) contenant un liquide ionique (46), au moins un orifice de sortie (28) en communication avec le réservoir, une vanne (16) agencée entre le réservoir et l'orifice de sortie, un capteur (53, 54) conçu pour détecter une concentration d'hydrogène et/ou une température et/ou de la chaleur, et un contrôleur conçu pour ouvrir la vanne et libérer le liquide ionique si un signal de sortie du capteur indique que ladite concentration d'hydrogène et/ou température est supérieure ou égale à une concentration d'hydrogène seuil et/ou à une température seuil.
Patent CA-3002983-A1 (CA)
Title: Filler fluid for fluidic devices
Inventor: VON HATTEN XAVIER
IPC: B01L3/00
Filed: 2016-10-20
Abstract: Disclosed herein are compositions and fluidic devices that include a filler fluid having a siloxane block co-polymer solubilized in the filler fluid. Also disclosed herein are related kits and methods for using the fluidic devices for various uses, such as the polymerase chain reaction or preparations for sequencing reactions.
Patent CA-3003705-A1 (CA)
Title: Creation of digital representations of well schematics
Inventor: ORTIZ THOMAS MANUEL
IPC: G06F17/21
Filed: 2015-12-02
Abstract: An example method of providing a digital representation of a well schematic includes storing a set of text strings and a set of image regions into a coordinate map. The method includes associating one or more text strings with one or more image regions. A text string is associated with an image region based on a context of the text string in the coordinate map. The method further includes linking one or more image regions with a corresponding catalogued image stored in a component database. The catalogued image represents a well schematic component. The method also includes generating a well schematic topology in accordance with the coordinate map and the one or more catalogued images linked with the one or more image regions. The method further includes updating the well schematic topology in accordance with one or more business rules.
Patent CA-3004478-A1 (CA)
Inventor: SINHA UTTAM K
IPC: G01N33/48
Filed: 2016-11-04
Abstract: A method for the early detection of head and neck cancer is provided. The method includes obtaining a saliva sample from a subject, determining the expression level of Desmoglien 3 (DSG3) in the saliva sample, and detecting head and neck cancer by the expression level of DSG3.
Patent CA-3005169-A1 (CA)
Inventor: FURUTA SHOUJI
IPC: A61K47/10
Filed: 2016-12-01
Abstract: L'invention concerne une préparation solide stabilisée de 2-{4-[N-(5,6-diphénylpyrazin-2-yl)-N-isopropylamino]butyloxy}-N-(méthylsulfonyl)acétamide. L'invention concerne également une préparation solide contenant de la 2-{4-[N-(5,6-diphénylpyrazin-2-yl) -N-isopropylamino]butyloxy}-N-(méthylsulfonyl)acétamide et du D-mannitol ayant une surface spécifique de 1,0 m2/g ou moins.
Patent CA-3005200-A1 (CA)
Inventor: OLSON RUSSELL WAYNE
IPC: B60P1/44
Filed: 2018-05-17
Abstract: A loader to load cargo onto the bed of a truck includes a frame having a rear roller, and a winch mountable onto the bed of the truck, and a platform having forward and rear wheels depending downwardly from corresponding front and rear ends thereof. The roller may include a cable guide formed circumferentially around the roller. A winch cable is selectively extendable from the winch over the cable guide on the rear roller, and to attach to the front end of the platform when in it's lowered pre-hoisting position. The front end of the platform is hoistable from its pre-hoisting position onto the rear roller where-upon continued winching-in of the cable onto the winch draws the rest of the platform over the rear roller so as to rest on the top of the frame. The platform is then winched to the front of the frame.
Patent CA-3005650-A1 (CA)
Inventor: QUINN REED
IPC: C11D13/10
Filed: 2016-11-16
Abstract: Cette invention concerne un appareil permettant de fabriquer ses propres de produits d'hygiène corporelle. L'appareil comprend une chambre de réaction conçue pour recevoir un ou plusieurs ingrédients de produit d'hygiène personnelle. L'appareil comprend également une cartouche qui renferme au moins un ou plusieurs ingrédients du produit d'hygiène personnelle, ainsi qu'un orifice de sortie conçu pour permettre l'évacuation du produit d'hygiène personnelle de la chambre de réaction.
Patent CA-3009505-A1 (CA)
Title: A chair and components
Inventor: PARKER KENT WALLACE
IPC: A47C3/027
Filed: 2017-02-03
Abstract: A chair support shell (105) has an integral back portion (107), seat portion (109), and joining portion (108) between the back portion and the seat portion. At least a major portion of the support shell (105) comprises a compliant structure, the compliant structure having a plurality of cells interconnected by a plurality of resilient members. The compliant structure provides compliance in the seat portion, compliance in the back portion, and compliance in the joining portion. The compliant structure enables recline of the back portion (107) relative to the seat portion (109).
Patent CA-3010039-A1 (CA)
Title: Automated communication design construction system
Inventor: REIHL AARON P
IPC: G06F17/00
Filed: 2018-06-29
Abstract: An automated communication design analysis and construction system includes that includes one or more intelligent communication design servers, comprising: a normalization module that converts communication content files for different recipients to normalized intermediate format files; an objects identification and quantification module that identifies text objects and image objects in the normalized intermediate format files; a cross recipient group analysis module configured to identify static global objects that are invariant between recipients, data variables, and variable global objects that vary between recipients in the normalized intermediate format files; and an intelligent communication content learning and constructing engine that can construct standard communication design files based on the static global objects, the data variables, and the variable global objects. A  data storage stores the communication content files and the standard communication design files. A    communication resource allocation server sends the standard communication design files to one or more product fulfillment centers.
Patent CA-3010107-A1 (CA)
Inventor: LEMAY DONAT
IPC: G03B11/00
Filed: 2016-12-21
Abstract: La présente invention se rapporte à un kit pour un adaptateur de filtre d'appareil photo, qui comprend un appareil de retenue de filtre et un appareil de mise en prise d'objectif. L'appareil de retenue de filtre comporte une partie de retenue de filtre et une première partie d'interface en regard de ladite partie de retenue de filtre. Cette partie de retenue est conçue pour retenir un filtre d'appareil photo. L'appareil de mise en prise d'objectif possède une partie de couplage à un objectif, ainsi qu'une seconde partie d'interface. La partie de couplage à un objectif est prévue pour être couplée à un objectif d'appareil photo. La seconde partie d'interface est destinée à assurer l'interface avec la première partie d'interface de l'appareil de retenue de filtre afin de former une mise en prise avec elle. L'interface définit un diamètre d'interface supérieur à un diamètre de couplage à un objectif. La présente invention a trait également à un procédé d'utilisation du kit.
Patent CA-3011149-A1 (CA)
Inventor: BEWLAY BERNARD PATRICK
IPC: G01N25/72
Filed: 2018-07-12
Abstract: Thermal degradation monitoring systems and methods determine at least one operating parameter of equipment that defines prior usage of the equipment, determine at least one thermal characteristic of the equipment using one or more thermal imaging cameras, determine whether both the at least one operating parameter and the at least one thermal characteristic indicate thermal degradation of the equipment, and implement one or more remedial actions on the equipment to change a state of the equipment in response to determining that the at least one operating parameter and the at least one thermal characteristic indicate thermal degradation of the equipment.
Patent CA-3011940-A1 (CA)
Title: Systems and devices for remotely operated unmanned aerial vehicle report-suppressing launcher with portable rf transparent launch tube
Inventor: MIRALLES CARLOS THOMAS
IPC: B64C13/20
Filed: 2010-09-09
Abstract: An unmanned aerial vehicle (UAV) launch tube (100, 400, 600, 1010, 1310) that comprises at least one inner layer of prepreg substrate (370) disposed about a right parallelepiped aperture (305), at least one outer layer of prepreg substrate (380) disposed about an aperture (305), and one or more structural panels (341-344) disposed between the at least one inner layer of prepreg substrate (340) and the at least one outer layer of prepreg substrate (380). An unmanned aerial vehicle (UAV) launch tube (100, 400, 600, 1010, 1310) that comprises a tethered sabot (700,740) configured to engage a UAV within a launcher volume defined by an inner wall, the tethered sabot (700,740) dimensioned to provide a pressure seal at the inner wall and tethered to the inner wall, and wherein the tethered sabot (700,740) is hollow having an open end oriented toward a high pressure volume and a tether (740) attached within a hollow (910) of the sabot (700) and attached to the inner wall retaining the high pressure volume or attach to the inner base wall (1013). A system comprising a communication node (1500-1505) and a launcher (1520) comprising an unmanned aerial vehicle (UAV) in a pre-launch state configured to receive and respond to command inputs from the communication node (1500-1505).
Patent CA-3012333-A1 (CA)
Title: Combining electronic monitoring with inhaled pharmacological therapy to manage cardiac arrhythmias including atrial fibrillation
Inventor: NARASIMHAN RANGACHARI
IPC: A61M15/00
Filed: 2017-02-01
Abstract: Disclosed herein are methods of treating cardiac arrhythmia with electronic monitoring in a timely manner. Also disclosed herein are systems for electronic monitoring of cardiac arrhythmia.
Patent CA-3012780-A1 (CA)
Inventor: MALCHUK BRADLEY W
IPC: B32B27/08
Filed: 2018-07-30
Abstract: A method of manufacturing a resealable vented multilayer film for use in heat sealable tray sealing machines. The method involves a first step of laminating a polymeric bottom layer, a pressure sensitive adhesive layer and a polymeric top layer to form a multi-layer film having a peripheral edge. The method involves a second step of perforating the multi-layer film. The method involves a third step of scoring the bottom layer to create a frangible connection. The frangible connection is spaced inwardly from a peripheral edge of the bottom layer. The top layer and the bottom layer remain adhered in a central portion of the multi-layer film, while the top layer separates from the bottom layer along the peripheral edge leaving a portion of the bottom layer as a resealing flange defined by the positioning of the frangible connection.