baber/WOPTO huggingface dataset:
Patent WO-2021150598-A1 (WO)
Title: Affinity peptide conjugated with antioxidant for protection of proteins from oxidation
Inventor: RAFIKOV RUSLAN
IPC: A61K38/00
Filed: 2021-01-20
Abstract: The present invention is a targeted peptide conjugated with an antioxidant, NO, to inhibit Akt nitration. The nitroxide peptide (NP), comprises two parts, one being the peptide part with the affinity to Akt near Tyr 350 residue (Ser-Arg-IIe-Arg-Ser; SRIRS) - and the other, a conjugated antioxidant - nitroxide (3-Carboxy-2,2,5,5-tetramethyl-3-pyrroline-1-yloxy) covalently attached to the free N-terminal amine. It can be utilized for treating pulmonary arterial hypertension (PAH) with potential application in other abnormal proliferative disorders such as cancer. The present invention features targeted selectivity for Akt nitration and does not affect Akt phosphorylation nor other physiological processes controlled by Akt signaling pathways. The present invention may also apply to other proliferative disorders including cancer or other disorders that cause or are caused by Akt nitration or protein oxidation.
Patent WO-2021158385-A1 (WO)
Title: Air fryer basket accessory for air fryer
Inventor: ITZKOWITZ BINYUMEN
IPC: A47J37/12
Filed: 2021-01-25
Abstract: An air fryer comprises: an air fryer basket; and an air fryer basket accessory. The fryer basket accessory comprises: a first plate configured to be supported by the air fryer basket; and a second plate rotatably connected to the first plate, the second plate configured to be supported by the air fryer basket.
Patent WO-2021162879-A1 (WO)
Title: Methods and compositions for antimicrobial use of synthetic lysine analogs, derivatives, mimetics, and prodrugs
Inventor: STEWART W
IPC: A61K31/454
Filed: 2021-01-30
Abstract: In an embodiment, the present disclosure relates to a method to prevent or inhibit proliferation, growth and formation, or survival of protozoans, bacteria, or fungal cells. In some embodiments, the method includes administering a composition including a synthetic lysine analog, derivative, mimetic, or prodmg. In some embodiments, the synthetic lysine analog, derivative, mimetic, or prodrug interacts with the protozoans, bacteria, or fungal cells to prevent or inhibit proliferation, growth and formation, or survival of the protozoans, bacteria, or fungal cells. In an additional embodiment, the present disclosure relates to a composition to prevent or inhibit proliferation, growth and formation, or survival of protozoans, bacteria, or fungal cells. In some embodiments, the composition includes a synthetic lysine analog, derivative, mimetic, or prodrug.
Patent WO-2021178108-A1 (WO)
Inventor: CHEN ZHEHUAI
IPC: G10L13/00
Filed: 2021-02-08
Abstract: A method (600) for training a speech recognition model (200) includes receiving a set of training utterance pairs (302) each including a non-synthetic speech representation (304) and a synthetic speech representation (306) of a same corresponding utterance (106). The method also includes determining a consistent loss term (352) for the corresponding training utterance pair based on a first probability distribution (311) over possible non-synthetic speech recognition hypotheses generated for the corresponding non- synthetic speech representation and a second probability distribution (312) over possible synthetic speech recognition hypotheses generated for the corresponding synthetic speech representation. The first and second probability distributions are generated for output by the speech recognition model. The method also includes updating parameters of the speech recognition model based on the consistent loss term.
Patent WO-2021173973-A1 (WO)
Inventor: MCNAMARA MICHAEL
IPC: H02J3/14
Filed: 2021-02-26
Abstract: A set of parameters are associated with a first set of computing components and a second set of computing components. The first set of computing components is located in a first region and the second set of computing components is located in a second region. The first region is positioned proximate a generation station control system associated with a generation station and the second region is positioned remotely from the generation station control system. Each computing component of the first set of computing components is configured to maintain constant power consumption during operation, and each computing component of the second set of computing components is configured to adjust power consumption during operation. The method also include adjusting power consumption at one or more computing components of the second set of computing components based on the set of parameters.
Patent WO-2021174188-A1 (WO)
Inventor: MACARY JENNIFER SULLIVAN
IPC: A61K8/29
Filed: 2021-03-01
Abstract: Methods for making a personal care product and a personal care product are provided. In one example, the method includes forming a first layer by an additive process. The first layer has a first composition that includes at least one filler component selected from the group of starch, bulking agent salt, granular acid, clay mineral, sorbitol, silica, titanium dioxide, and zinc oxide. A binder is applied to the first layer. A second layer is formed by the additive process overlying the binder. The second layer has a second composition that includes at least one filler component selected from the group of starch, bulking agent slat, granular acid, clay mineral, sorbitol, silica, titanium dioxide, and zinc oxide. At least one of the first composition and the second composition further includes at least one surfactant.
Patent WO-2021178897-A1 (WO)
Inventor: LIANG BIN
IPC: E05B65/46
Filed: 2021-03-05
Abstract: A leak containment system (50) includes a mounting bracket (62), a tray (64), and a locking mechanism (66). The mounting bracket has a first rail (68), a second rail (70), and a panel (72) extending between the first rails and the second rail. The panel is vertically offset from feet (74, 78) formed on the first rail, and a channel (90) is defined by at least the first rail and an underside of the panel. The tray is removably received within the channel. The tray includes a bottom surface (92) surrounded by perimeter walls (94, 96, 98, 100) that together define a fluid container. The perimeter walls include a front perimeter wall (100) that extends upwardly above the other walls. The locking mechanism is coupled to the mounting bracket and is configured to selectively engage the front perimeter wall of the tray to restrict movement of the tray outward from the channel.
Patent WO-2021211245-A1 (WO)
Title: Determining a geological correlation with a wellbore position
Inventor: COMBS JEREMY JAMES
IPC: G01V3/18
Filed: 2021-03-16
Abstract: This disclosure presents a process to determine an alignment parameter for geosteering a wellbore undergoing drilling operations. The process can receive one or more azimuthal image log data sets, one or more geology logs, and other input parameters. The image log data sets can be transformed to better approximate the geology logs, such as transforming a 3D representation to a 2D representation and flattening out curves represented in the original image log data. The geology logs or transformed image log data can then be moved to create an approximate alignment between the other log data. The movement, which can be a sliding movement, a linear movement, a tilting movement, an angling movement, or a rotating movement, can be used to determine the determined alignment parameter or final alignment parameter. The alignment parameter can be used as input into a geosteering system for the wellbore.
Patent WO-2021206878-A1 (WO)
Title: Payload measurement system for machine with hauling body
Inventor: KRONE JOHN J
IPC: G01G19/12
Filed: 2021-03-17
Abstract: A payload measurement system (200) can be used to measure the payload added to a machine (100) supported on a plurality of walking beams (130). A plurality of load cell sensors (202) is mounted to the walking beams (130) in locations where, when the walking beam (130) bends, the sensors (202) are placed under load (248). The load cell sensors (202) include a symmetrical strain bar (220) having first and second mounting ends (230,232) connected by a connecting span (234), wherein the end thickness (264) is greater than the span thickness (269) of the connecting span (234). The connecting span (234) is disposed between and spaced apart from an upper plane (260) and a lower plane (262) with which the surfaces of the mounting ends (230) are aligned.
Patent WO-2021211504-A1 (WO)
Title: Nasal spray formulation with moisturizing benefits
Inventor: AKUNURI VENKATA VIJAY KUMAR
IPC: A61K9/00
Filed: 2021-04-13
Abstract: Aspects of the present invention are directed to a nasal spray formulation comprising: at least one active pharmaceutical ingredient, glycerin, polyethylene glycol, and dextrose. Formulations of the present invention provide moisturizing benefits and retain at least about 3% water when exposed to about 80% relative humidity at a temperature of about 23°C for about 750 minutes in a Dynamic Vapor Sorption (DVS) test.
Patent WO-2021221909-A1 (WO)
Inventor: FU QIANG
IPC: C03C10/00
Filed: 2021-04-14
Abstract: An optical diffuser can comprise an amorphous phase and a crystalline phase comprising lithium disilicate and one or more of ß-spodumene or ß-quartz comprising a median grain size ranging from about 500 nanometers to about 1,000 nanometers. The crystalline phase can be dispersed throughout a volume of the optical diffuser. The optical diffuser can comprise, on an oxide basis in mol %, SiO 2 : 60-75; Al 2 O 3 : 2-9; Li 2 O: 17-25; and Na 2 O + K 2 O: 0.5-6. Methods of making an optical diffuser can comprise forming a mixture by melting together, on an oxide basis in mol %, SiO 2 : 60-75; Al 2 O 3 : 2-9; Li 2 O: 17-25; and Na 2 O + K 2 O: 0.5-6. Methods can comprise forming a ribbon from the mixture. Methods can comprise heating the ribbon about 850°C to about 900°C for about 0.5 hours to about 6 hours.
Patent WO-2021226234-A1 (WO)
Title: Substituted tolyl fungicides and their mixtures
Inventor: BEREZNAK JAMES
IPC: A01N43/647
Filed: 2021-05-05
Abstract: Disclosed is a fungicidal composition comprising (a) at least one compound selected from the compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein A, Q, R 1 , R 2 , R 3 , R 4 , W and Y are as defined in the disclosure; and (b) at least one additional fungicidal compound. Also disclosed is a method for controlling plant diseases caused by fungal plant pathogens comprising applying to the plant or portion thereof, or to the plant seed, a fungicidally effective amount of a compound of Formula 1, an N-oxide, or salt thereof (e.g., as a component in the aforesaid composition). Also disclosed is a composition comprising: (a) at least one compound selected from the compounds of Formula 1 described above, N-oxides, and salts thereof; and at least one invertebrate pest control compound or agent.
Patent WO-2021231596-A1 (WO)
Title: Secured validation system
Inventor: MORENO BERNARDO
IPC: H04L29/06
Filed: 2021-05-12
Abstract: Methods for securely validating a test are provided. In one aspect, the method includes receiving an enrollment request from a user device associated with an individual. The method includes generating a profile associated with the individual and storing the profile on a blockchain network, wherein the profile comprises profile data. The method includes receiving a test result associated with a test of the individual and updating the profile with the test result. The method includes determining whether a facility associated with the test result is an approved certifying facility. The method includes creating, responsive to determining that the facility is one of the approved certifying facilities, a unique code associated with the individual, wherein the unique code comprises an indication of the test result. The method includes transmitting the unique code to the user device associated with the individual. Systems and machine-readable media are also provided.
Patent WO-2022072000-A1 (WO)
Inventor: FANELLO SEAN
IPC: G06T11/00
Filed: 2021-05-17
Abstract: Apparatus and methods related to applying lighting models to images of objects are provided. An example method includes applying a geometry model to an input image to determine a surface orientation map indicative of a distribution of lighting on an object based on a surface geometry. The method further includes applying an environmental light estimation model to the input image to determine a direction of synthetic lighting to be applied to the input image. The method also includes applying, based on the surface orientation map and the direction of synthetic lighting, a light energy model to determine a quotient image indicative of an amount of light energy to be applied to each pixel of the input image. The method additionally includes enhancing, based on the quotient image, a portion of the input image. One or more neural networks can be trained to perform one or more of the aforementioned aspects.
Patent WO-2022250650-A1 (WO)
Title: Système et procédé de vérification d'essais cliniques centrés sur des cliniciens
Inventor: IKEGUCHI EDWARD
IPC: H04L29/06
Filed: 2021-05-24
Abstract: La présente invention concerne un système et un procédé informatisés permettant à une personne du site médical, telle qu'au moins un professionnel médical (expert clinique) de répondre à des questions à partir d'un questionnaire d'essai clinique (tel qu'un formulaire de rapport de cas électronique (eCRF)) pertinentes pour un essai clinique d'un traitement médical par réalisation d'une capture de source et délimitation de zones spécifiques de l'image de capture de source qui contiennent une réponse. Le système permet un flux de travail, moyennant quoi une image d'une réponse, par exemple, un extrait de capture de capture d'écran, obtenu par l'intermédiaire de clics de souris, est utilisée au lieu de la transcription de valeurs alphanumériques.
Patent WO-2021262559-A1 (WO)
Inventor: ZAGHETTO ALEXANDRE
IPC: G06T9/40
Filed: 2021-06-20
Abstract: Trisoup node size per slice enables flexibility when encoding a point cloud. Instead of each block/node being the same size, a user or machine is able to indicate block/node sizes such that regions of interest are able to have smaller node sizes for more specificity in that region.
Patent WO-2022016017-A1 (WO)
Title: Intubation infection control tent
Inventor: KLAFTENEGGER CHRISTOPHER COLLIN
IPC: A61G10/04
Filed: 2021-07-15
Abstract: An intubation infection control tent system is described. In an example implementation, an infection control tent includes a cover that forms a space in which a patient can be positioned, the cover creating an infectious barrier between the patient and an external environment, one or more support channels integrated into the cover that provide a rigid structure to the cover, and a drape skirt that connects to an edge of the cover and drapes over a portion of the patient.
Patent WO-2022036122-A1 (WO)
Title: Pumped heat energy storage system with district heating integration
Inventor: BOLLINGER BENJAMIN R
IPC: F01K3/02
Filed: 2021-08-12
Abstract: The present disclosure provides pumped heat energy storage systems that can be used to store and/or extract electrical energy. A pumped heat energy storage system of the present disclosure can store energy by operating as a heat pump, whereby net work input can be used to transfer heat from the cold side to the hot side. A working fluid of the system is capable of efficient heat exchange with heat storage fluids on a hot side of the system and on a cold side of the system. Such pumped energy storage systems can be beneficially integrated with district heating systems to provide and/or supplement heat supplied to the district heating systems.
Patent WO-2023022730-A1 (WO)
Inventor: BRAZ PAULO ALVES
IPC: G01V1/40
Filed: 2021-08-20
Abstract: Un procédé consiste à acquérir des données de construction de puits historiques associées à un ensemble de puits historiques. Le procédé consiste également à élaborer un modèle de construction de puits à l'aide du corpus de données de construction de puits historiques. De plus, le procédé consiste à acquérir des données de construction de puits en temps réel pendant une opération de construction de puits et à appliquer le modèle de construction de puits aux données de construction de puits en temps réel pour identifier des changements d'un paramètre de construction de puits. En outre, le procédé consiste à émettre une commande pour mettre à jour l'opération de construction de puits à l'aide des changements du paramètre de construction de puits.
Patent WO-2023033783-A1 (WO)
Title: Determining location and sizing of a new power unit within a current system architecture of a power system or a grid
Inventor: WU XIAOFAN
IPC: G06F111/20
Filed: 2021-08-30
Abstract: A system determines a location and a size of a new power generation or power regulating unit within a current system architecture of a power system including a plurality of power generation units. The system comprises a controller including a processor and a memory, computer-readable logic code stored in the memory which, when executed by the processor, causes the controller to execute a hybrid algorithm as a combination of a data-driven algorithm and a model-based algorithm to determine an optimal location and size of the new power generation or power regulating unit. The data-driven algorithm encodes a location and a size information. The controller to enable the model-based algorithm to optimize performance of a selected location and size of the new power generation or power regulating unit, which is based on a linearized system or a nonlinear system to provide guidance for the data-driven algorithm to incorporate physical rules and verify a new system architecture.
Patent WO-2022056181-A1 (WO)
Inventor: LITMAN ERIC
IPC: A61H7/00
Filed: 2021-09-09
Abstract: L'invention concerne un système, un procédé et un appareil permettant de générer un plan de massage thérapeutique dynamique, autonome, à apprentissage automatique et modifiable. L'invention concerne un système, un procédé et un appareil permettant de déterminer et d'exécuter la planification de mouvements pour diriger un ou plusieurs bras robotiques en vue d'exécuter une séquence de mouvements tout en maintenant un contact entre leurs effecteurs terminaux et un sujet.
Patent WO-2023043446-A1 (WO)
Inventor: HSIEH HSING-HUNG
IPC: G06F3/01
Filed: 2021-09-16
Abstract: Dans certains exemples, un support lisible par ordinateur stocke un code exécutable qui, lorsqu'il est exécuté par un processeur d'un dispositif électronique, amène le processeur à stocker une relation entre un motif de regard de l'utilisateur et des premières conditions du dispositif électronique, à identifier des secondes conditions du dispositif électronique, à déterminer si les secondes conditions correspondent aux premières conditions, et en réponse à ce que les secondes conditions correspondent aux premières conditions, à faire fonctionner de façon sélective un panneau d'affichage du dispositif électronique avec différentes caractéristiques d'affichage sur la base du motif de regard de l'utilisateur.
Patent WO-2022093989-A1 (WO)
Inventor: MCHREF YEHIA
IPC: B01D15/16
Filed: 2021-10-27
Abstract: A method, system, and apparatus for chromatography comprises a chromatographic system can include a column packed with mesoporous graphitized carbon (MGC). The MGC serves as an ideal stationary phase and facilitates the efficient isomeric separation of compounds such as permethylated glycans with unprecedented 10mm long column. The column is anticipated to be an efficient and economical replacement for nanoflow PGC column which was phased out by the manufacturer due to poor performance and lack of reproducibility.
Patent WO-2022109425-A1 (WO)
Title: Dispositifs et méthodes d'échantillonnage de fluides gastro-intestinaux et d'évaluation de la fonction gastro-intestinale
Inventor: SHALON TIDHAR
IPC: A61B10/02
Filed: 2021-11-22
Abstract: Des modes de réalisation concernent des dispositifs et des méthodes d'échantillonnage de fluides gastro-intestinaux et d'évaluation de la fonction gastro-intestinale à l'aide d'un dispositif comprenant un tube d'échantillonnage.
Patent WO-2022132564-A1 (WO)
Title: Laser powder bed fusion additive manufacturing in-process monitoring and optimization using thermionic emission detection
Inventor: MARTIN AIDEN ALEXANDER
IPC: B33Y10/00
Filed: 2021-12-09
Abstract: The present disclosure relates to a system which may have an electronic controller, an optical light source controlled by the electronic controller which generates a beam having an output power level, and a current measuring subsystem (CMS) electrically coupled to a conductive substrate (e.g., metal substrate (MS)) while a powder bed layer (PBL) is deposited on the MS. The CMS may be in communication with the electronic controller and detects a current flow as at least one of the MS or the PBL is heated when the beam is scanned over the PBL. The CMS generates a current flow signal in accordance with the detected current flow. The current flow signal is used by the electronic controller to determine when the temperature of at least one of the substrate or the PBL is at least one of above or below a desired temperature.
Patent WO-2022133265-A1 (WO)
Inventor: ALDRICH JANE
IPC: A61K47/10
Filed: 2021-12-17
Abstract: L'invention concerne des composés de Formule (I), ainsi que des compositions, des procédés, des utilisations et des kits les comprenant. Les composés, compositions, procédés, utilisations et kits décrits ici sont utiles dans le traitement de maladies ou de troubles comprenant le cancer, le VIH et de troubles liés à l'angiogenèse.
Patent WO-2022133344-A1 (WO)
Inventor: HEYES JAMES
IPC: A61K48/00
Filed: 2021-12-20
Abstract: The invention provides a compound of compound of formula (I): or a salt thereof, wherein R1, n, L, and X have any of the values described herein, as well as compositions and lipid nanoparticles comprising a compound of formula I, and their use for delivering therapeutic agents such as siRNA and mRNA.
Patent WO-2022040647-A1 (WO)
Inventor: BRANDAO MELISSA
IPC: A61D7/00
Filed: 2021-01-29
Abstract: Apparatus (100) and method (500) for autonomously administering a pharmaceutical agent (180, 324), such as an insecticide, to an animal (112, 400). A tag assembly (102, 402, 406, 408, 410) is attached (502) to the animal at a suitable location such as an outer ear (114). The tag assembly includes a reservoir (172, 198, 322) to retain the pharmaceutical agent. An actuator (174, 326, 366) of the tag assembly is configured to open (510) the reservoir responsive to a control signal (174A) provided from a control circuit (142, 177, 200, 234, 254, 264, 272). An application mechanism (176, 186, 186A, 186B, 192, 328, 354) facilitates a transfer of the pharmaceutical agent to the animal (512) in response to the actuator. In some cases, the control signal may be transmitted to the tag assembly from an external source (106, 107, 108, 109, 110) via a wireless connection. In other cases, the control signal may be generated using a sensor (150, 152, 162, 164, 166, 270). The tag assembly may include multiple reservoirs (172A, 172B) so that applications of the agent can be carried out at different times and under different conditions as required.