baber/WOPTO huggingface dataset:
Patent CA-2100626-A1 (CA)
Title: 4-aminoquinazoline derivatives
Inventor: LEE SUNG J
IPC: C07D401/04
Filed: 1993-07-15
Abstract: ABSTRACT     The compounds of the formula:       (I) wherein R1 is H or alkyl; Y is bond or alkylene; A is (i) -CyA-(R2)1, (ii) -O-R0 or -S(O)p-R0 or (iii) -NR16R17; in which R0 is hydrogen, C1-4 alkyl, hydroxy-C1-4 alkyl or -CyA-(R2)1; R16 and R17 independently are hydrogen or C1-4 alkyl; p is 0-2; CyA is (1) 3-7 membered monocyclic carbocyclic ring, (2) 4-7 membered monocyclic hetero ring containing as hetero atoms, one N atom, one N and one O atoms, two N and one O atoms, or one N and two O atoms, (3) 4-7 membered monocyclic hetero ring containing as hetero atoms, 1 or 2 O or S atoms; R2 is (1) H, (2) alkyl, (3) alkoxy, (4) -COOR5, in which R5 is H or alkyl, (5) -NR6R7, in which R6 and R7 independently are H or alkyl, (6) -SO2NR6R7, in which R6 and R7 are as hereinbefore defined, (7) halogen, (8) CF3, (9) NO2 or (10) CF3O; Z is bond, methylene, ethylene, vinylene or ethynylene; CyB is (1) 4-7 membered monocyclic hetero ring containing as hetero atoms, one to three N atoms, (2) 4-7 membered monocyclic hetero ring containing as hetero atoms, one or two O or S atoms; R3 is H, alkyl, alkoxy, halogen or CF3; R4 is (1) H, (2) alkyl, (3) alkoxy, (4) -COOR8, in which R8 is H or alkyl, (5) -NR9R10, in which R9 is hydrogen, C1-4 alkyl or phenyl(C1-4 alkyl) and R10 is H or alkyl, (6) -NHCOR11, in which R11 is alkyl, (7) -NHSO2R11, in which R11 is as hereinbefore defined, (8) SO2NR9R10, in which R9and R10 are as hereinbefore defined, (9) -OCOR11, in which R11 is as hereinbefore defined, (10) halogen, (11) CF3, (12) OH, (13) NO2, (14) CN or (15) SO2N=CHNR12R13 in which R12 is H or alkyl and R13 is alkyl, (16) -CONR14R15 in which R14 is H or alkyl or phenylalkyl and R15 is alkyl or (17) C1-4 alkylthio, (18) C1-4 alkyl-SO- or (19) C1-4 alkyl-SO2-, (20) ethynyl, (21) HOCH2-, (22) tri(C1-4 alkyl)silyl or (23) acetyl; and 1, m and n independently are 1 or 2; with the proviso that (1) the group of the formula: -CyA-(R2)1 is not a cyclopentyl and trifluoromethylphenyl group when Y is a bond, that (2) a CyB ring should not bond to Z through a nitrogen atom in the CyB ring when Z is vinylene or ethynylene, that (3) a CyB ring should not pyridine or thiophene when CyA is a ring of CyA-(7) and that (4) Y is not a single bond, when A is (ii) -O-R0 -S(O)p-R0 or (iii) -NR16R17; and acid addifion salts thereof, salts thereof, and hydrates thereof; have inhibitory effect on cGMP-PDE, or additionally on TXA2 synthetase.
Patent CA-2102804-A1 (CA)
Title: 3'-end blocked oligonucleotides
Inventor: AGRAWAL SUDHIR
IPC: A61K48/00
Filed: 1992-05-08
Abstract: ABSTRACT OF THE DISCLOSURE           The invention provides oligonucleotides having 3'-ends  blocked  by  cap  structures  and  having  one  or  more artificial internucleoside linkage.  Such oligonucleotides are resistant to in vivo degradation and extension, and thus have superior half-life in vivo.
Patent CA-2103391-A1 (CA)
Title: Foldable bottle with fastening element
Inventor: BENIACAR GIACOMO
IPC: B65D1/02
Filed: 1993-11-18
Abstract: ABSTRACT A bottle (10, 110) made of flexible material which can be folded or rolled up into a deformed configuration of limited dimensions. The bottle comprises, between the pouring neck (14, 114) and side walls (15, 115), elements which engage with a fastening element (17, 117) which can be fitted onto the bottle to keep it in the deformed configuration.
Patent CA-2103569-A1 (CA)
Title: Flexible tube for the packaging of pasty products
Inventor: SIGEL ALWIN
IPC: B65D35/10
Filed: 1992-11-30
Abstract: Abstract The object of the invention is a container (1) especially for chemical substances consisting of a substance chamber (2) of tubular plastic film (10) and a funnel-shaped headpiece (3). The film consists of low-density and the headpiece of high-density plastic. The tubular plastic film (10) is secured in the headpiece (3) by pressing. The headpiece (3) may be divided into a plate-shaped (4) and a tubular (5) section. On the side towards the substance chamber, the plate-shaped section (4) has an annular groove. The plastic film (10) is pressed into place by a securing ring with a U-shaped cross-section which can be pressed into the annular groove. A snap mechanism holds the securing ring firmly in the groove. The tubular plastic film (10) is firmly pressed between the securing ring and the groove walls. The container (1) can be closed at the rear by a suitable closure device.
Patent CA-2104319-A1 (CA)
Title: Support structure with wiring
Inventor: FARHAM HOWDEN W
IPC: H05K7/18
Filed: 1993-08-18
Abstract: ABSTRACT OF THE DISCLOSURE     A support structure of the kind used in supermarkets and other self-service shops comprises a series of slotted upright members 12 and brackets 16 which are connected to the upright members by having teeth which enter into the slots. Conductor tracks 36 extend along passages 32 in the upright members, and electrical contact with conductors carried by the conductor tracks is established by means of electrical connectors 48 having tongues 50 which enter into the passages through slots which are unoccupied by teeth.
Patent CA-2105041-A1 (CA)
Inventor: MESZLENYI IVAN
IPC: H03K3/0231
Filed: 1993-08-27
Abstract: A current controlled oscillator comprises an optocoupler driven by a control current; a diode bridge means comprising four high speed diodes where the polarized input is connected to the transistor of said optocoupler; a resistor means connected between the transistor output of said optocoupler and the polarized input of said diode bridge; an inverting Schmitt trigger means having well defined low and high thresholds where the inverting polarized input and output are connected to the non-polarized input of said diode bridge; a timing resistor means connected between the input and output of said Schmitt trigger; a timing capacitor means connected between the negative input and ground of said Schmitt trigger; a pair of voltage references establishing the low and high thresholds of said inverting Schmitt trigger.
Patent CA-2106324-A1 (CA)
Title: Continuity tester
Inventor: PAGANO BIAGIO
IPC: G01R31/04
Filed: 1993-09-16
Abstract: ABSTRACT           The present invention provides a continuity tester suitable for testing different types of devices and circuits wherein first and second members are hingedly connected together, the first and second members each having an electrically conductive surface element associated therewith, the arrangement being such that the conductive surface element of the first member is connected to a negative side of a test circuit and the conductive surface element of the second member is connected to the positive of a test circuit and the first and second members can then assume different angles with respect to each other to enable many different devices to be tested through manipulation of the first and second members.
Patent CA-2108255-A1 (CA)
Title: Anti-cancer compounds
Inventor: PATTERSON LAURENCE H
IPC: A61P31/04
Filed: 1992-04-10
Abstract: Compounds of formula (I), in which R1 is A-N(O)R'R" and R2, R3 and R4 are each separately selected from hydrogen, X and NH-A-N(O)R'R" wherein X is hydroxy, halogeno, amino, C1-4 alkoxy or C2-8 alkanoyloxy, A is a C2-4 alkylene group with a chain length between N or NH and N(O)R'R" of at least 2 carbon atoms and R' and R" are each separately selected from C1-4 alkyl groups and C2-4 hydroxyalkyl and C3-4 dihydroxyalkyl groups in which the carbon atom attached to the nitrogen atom does not carry a hydroxy group and no carbon atom is substituted by two hydroxy groups, or R' and R" together are a C2-6 alkylene group which with the nitrogen atom to which R' and R" are attached forms a heterocyclic group having 3 to 7 atoms in the ring, and physiologically acceptable salts thereof are of value in the treatment of cancer.
Patent CA-2110022-A1 (CA)
Inventor: LAROCHELLE LOUIS-PHILIPPE
IPC: E05C17/36
Filed: 1993-11-25
Abstract: La chaîne hybride a pour fonction de pouvoir cadenasser un objet à partir d'un autre objet, par exemple une motocyclette après un poteau, comme le font d'ailleurs tous les systèmes de cadenassages traditionnels. Cependant, la chaîne hybride combine la souplesse d'un câble d'acier ou d'une chaîne ordinaire avec la quasi indestructibilité d'une barre d'acier. L'utilisateur jouit ainsi de deux avantages à la fois, avantages qui sont très rarement compatibles. Cette combinaison de caractéristiques se fait en enveloppant un câble d'acier d'un blindage souple, extrêmement difficile à couper ou à scier.
Patent CA-2110713-A1 (CA)
Title: Method and system for optimizing activity threshold in activity based rate adaptive pacemakers
Inventor: BENNETT TOM D
IPC: A61N1/365
Filed: 1993-01-14
Abstract: A pacemaker capable of automatically adjusting the activity threshold setting of its activity sensor signal processing circuitry to its optimal value is disclosed. In one embodiment, the pacemaker maintains a running average of zero activity time and a cumulative summation of zero activity time over a predetermined history period. Periodically, the pacemaker computes a time difference between the running average of zero activity time and the cumulative summation of zero activity time, and adjusts the activity threshold of the activity sensor signal processing circuitry according to this computation. By basing the adjustment of activity threshold on a long-term average of zero activity time, the effects of cycle-to-cycle variation in sensed zero activity time are minimized. In another embodiment, the pacemaker periodically computes a time difference between a preprogrammed margin value and the cumulative summation of zero activity time. If the time difference is less than the predetermined margin, the activity threshold is increased. If the time difference is greater than the predetermined margin, the activity threshold is decreased.
Patent CA-2110853-A1 (CA)
Title: Delayed, sustained release pharmaceutical preparation
Inventor: EICHEL HERMAN J
IPC: A61P11/14
Filed: 1993-12-07
Abstract: Abstract A delayed, sustained-release pharmaceutical preparation is provided in which a water-soluble drug core is surrounded by a hydratable diffusion barrier which delays drug release for about 2-10 hours.   The hydratable diffusion barrier comprises a film-forming polymer such as an acrylic resin or ethyl cellulose and an additive which controls the rate of hydration and permeability of the hydratable diffusion barrier selected from the group consisting of fully esterified acrylic resins containing quaternary amine side chains, lubricants, anionic surfactants, plasticizers, inert water-soluble materials, and mixtures thereof.  In the preferred sustained-release pharmaceutical preparation, the film-forming polymer is combined with the additive and coated onto core drug granules to produce a diffusion barrier surrounding the core drug and form microparticles which may then be admixed with an immediate release drug.
Patent CA-2115275-A1 (CA)
Title: Amino acid, ester and/or catechol contrast agents for mri
Inventor: WHITE DAVID L
IPC: A61K49/06
Filed: 1992-08-07
Abstract: The present invention relates to the preparation of amino acid containing compounds which also have multiple carboxylic acid functional groups. Paramagnetic metal (II) or (III) ion chelate complexes are formed using these compounds for use as intravenous contrast agents to produce enhanced contrast magnetic resonance images of the heart, liver, biliary tree or upper small intestine. The mono and di-amino acids (and their carboxylic esters carboxylic amides, and catechols) of EDTA, DTPA, and the like are prepared.  The paramagnetic metal (II) or (III) ion complexes are formed and produce T1-related contrast effects in MR images. The compounds and complexes also appear to have low toxicities and to be relatively rapidly and completely cleared from the tissue of a living mammal, e.g. a human being.
Patent CA-2115424-A1 (CA)
Title: Immunostimulation
Inventor: GECZY ANDREW F
IPC: A61P31/04
Filed: 1992-08-10
Abstract: The present invention provides novel compositions and methods for increasing immune responsiveness, in particular T-cell responsiveness in patients with an immunodeficiency, particularly in T-cell function. The present invention is particularly useful for increasing responsiveness of helper T-cells. The method of the present invention comprises administering to a patient a protein selected from the group consisting of TraT, OmpA, OmpF and parts thereof and a pharmaceutically acceptable carrier. Preferably, at least one other antigen is administered. The present invention should be particularly useful in the treatment of HIV positive patients.
Patent CA-2115658-A1 (CA)
Inventor: BRADFORD CHRISTOPHER J
IPC: C08G12/40
Filed: 1992-07-29
Abstract: Dans un procédé de réticulation d'un polymère, la fonctionnalité beta-dicarbonyle est présente sous forme d'un diluent réactif et/ou d'un solvant réactif, et/ou d'une entité de réticulation. Le composé beta-difonctionnel réagit avec le formaldéhyde qui est libéré pendant la réaction de réticulation (ou bien qui est présent) de sorte que la libération du formaldéhyde soit moindre qu'elle ne le serait autrement. Le formaldéhyde qui réagit avec le composé beta-dicarbonyl est soit incorporé dans le réseau polymère réticulé, soit libéré sous la forme d'un produit de réaction qui n'est pas dangereux pour l'environnement tel que le formaldéhyde n'ayant pas réagi. Le procédé permet de réduire la libération du formaldéhyde lors de la réticulation à des niveaux qu'on ne peut pas obtenir autrement. De plus, le procédé permet la réduction de la quantité de solvant organique utilisé.
Patent CA-2116001-A1 (CA)
Title: Pump or compressor unit
Inventor: MOHN FRANK
IPC: F04D3/00
Filed: 1992-08-19
Abstract: A contra-rotating pump or compressor unit is made axially compact by moving the fluid along concentric annular flow path portions between which the flow direction is reversed. The unit can comprise concentric contra-rotating sleeves (31, 32, 35) provided with impeller vanes or blades and defining the flow path portions between them, or axially adjacent contra-rotating impeller assemblies each comprising concentric rings with impeller vanes between them. The flow direction reversal can be effected either by fixed housing portions co-operating with the sleeves or rings or by annular walls (34, 62) connecting alternate sleeves (31, 32, 35) or rings.
Patent CA-2119797-A1 (CA)
Title: Method for preparing multilayer dielectric powder condensers
Inventor: TAKAHASHI YASUNORI
IPC: H01G4/30
Filed: 1994-03-24
Abstract: ABSTRACT       The object of the present invention is to provide a method for preparing small-size and large capacity multilayer dielectric powder condensers capable of employing as the inner electrode materials inexpensive copper alloys or nickel alloys.     The method for preparing multilayer dielectric powder condensers according to the present invention comprises steps of: providing a fine dielectric powder having a dielectric film on the surface of a metal powder or a semiconductor powder; preparing a pasty material by kneading the dielectric powder with an organic binder; forming a filmy sheet from the pasty material; applying a paste containing a metal powder for forming electrode on the surface of the filmy sheet and drying the applied sheet; piling a plurality of the sheets; placing the piled sheets between thin glass sheets made from a paste prepared by kneading a glass powder and an organic binder and pressing them together; and subjecting the piled and pressed sheets to a heat-treatment.
Patent CA-2121327-A1 (CA)
Title: Pesticide and Fungicide
Inventor: SHEEN RONALD JAMES
IPC: A01N59/20
Filed: 1992-10-14
Abstract: A method of producing a copper silicate product, said method comprising reading a copper salt with an alkali silicate in an acidic solvent to produce an aqueous solution of acidified copper silicate capable of being used as a fungicide or pesticide.
Patent CA-2125955-A1 (CA)
Title: Razor, in particular a disposable razor
Inventor: FRICK HANS-RUEDI
IPC: B65D83/40
Filed: 1993-10-18
Abstract: ABSTRACT OF THE DISCLOSURE      In a razor with a handle-like lather container and detachable cap that covers and can be moved relative to a lather discharge valve of the lather container, which valve is enclosed by a linking ring, at least two projecting catches are devised as guide pieces in the cap approximately radially opposite each other on either side of a central pin, and can each be sunk into a corresponding slot in the linking ring, each slot being separated from a guide surface of the linking ring by a bead.  Each slot can be flanked by two beads, which are adjoined by a wedge-shaped, upwardly inclined surface.
Patent CA-2126253-A1 (CA)
Inventor: GE DAVID W
IPC: H01L23/427
Filed: 1994-06-20
Abstract: Faster computer generates more heat. For fast machines with Pentium and some fast 486 CPUs, it is necessary to make extra effort to cool the CPUs. This inventive CPU cooler is a solid device without power to operate and need no maintenance.
Patent CA-2127972-A1 (CA)
Title: Enzymatic processes for the resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes
Inventor: PATEL RAMESH N
IPC: C12P17/16
Filed: 1994-07-13
Abstract: Abstract ENZYMATIC PROCESSES FOR THE RESOLUTION OF ENANTIOMERIC MIXTURES OF COMPOUNDS USEFUL AS INTERMEDIATES IN THE PREPARATION OF TAXANES        Methods for the enzymatic resolution of mixtures of enantiomers, such as .beta.-lactam compounds, which may be employed as intermediates in the preparation of taxanes bearing a C-13 sidechain containing a heterocyclic or cycloalkyl group, the latter useful in the pharmaceutical field.
Patent CA-2130896-A1 (CA)
Title: Microperforated film and packaging bag made therefrom
Inventor: PORCHIA JOSE
IPC: B65D85/50
Filed: 1993-04-05
Abstract: A flexible film (11) and flexible food storage bag (10) for packaging produce such as vegetables and fruits wherein the film or bag has plurality of microholes (12) specifically designed to allow the produce to breathe in a controlled rate such that localized condensation and weight loss is minimized; which in turn reduces microbial (bacteria and mold) growth and reduces produce mushiness (softness) respectively.
Patent CA-2131892-A1 (CA)
Title: Clearing apparatus and carriage for clearing apparatus
Inventor: FOSTER THOMAS E
IPC: A01D34/68
Filed: 1993-03-08
Abstract: A clearing apparatus (10.7) which includes a clearing device (12.7) for use in clearing operations, and a carriage (14.7) for supporting the clearing device (12.7) during use. The clearing device (12.7) is of conventional type and has an elongated support tube (16.7), a clearing head (18) mounted at one end of the support tube (16.7), and a motor (20) mounted at the other end of the support tube (16.7). The carriage (14.7) includes a frame (22.7), a single support wheel (24) which is rotatably mounted on the frame (22.7) to support the frame (22.7), and a guide handle (28.7) for use in guiding the apparatus, and the frame (22.7) has a mounting bracket (201) which mounts the support tube (16.9) on the frame (22.7) so that the clearing apparatus (10.7) will be supported proximate its center of gravity on the support wheel (24) during use.
Patent CA-2132411-A1 (CA)
Title: Enzymatic esterification of long-chain racemic acids and alcohols
Inventor: TRANI MICHAEL
IPC: C12P7/22
Filed: 1994-09-19
Abstract: The invention disclosed relates to a process for the enzymatic esterification and transesterification of racemic carboxylic  acids  and  alcohols  in  which  the  reaction products  predominantly  include  the  ester  of  the more reactive acid or alcohol enantiomer and the less reactive acid or alcohol enantiomer,  wherein the reactions are effected, preferably in a solventless medium, and the by-product water or short-chain alcohol is removed as it is formed.
Patent CA-2132779-A1 (CA)
Title: Adapter assembly for cannula hub syringe
Inventor: CHOUDHURY HRISHIKESH
IPC: A61M5/34
Filed: 1994-09-23
Abstract: ABSTRACT       A multiple configuration adapter assembly is provided for a prefilled emergency syringe and includes a cylindrical sheath, a removable sharp needle assembly and a luer extension assembly.
Patent CA-2132915-A1 (CA)
Title: Acoustics Energy Dissipator for Furnace
Inventor: BIGHAM DAVIS L
IPC: F23M20/00
Filed: 1994-09-26
Abstract: The present invention involves a combustion box of a gas furnace which experiences oscillating combustion. The combustion box employs an opening in the housing which is tautly covered with a diaphragm made of elastic material such as silicone rubber. The elastic diaphragm transmits noise and vibration generated by the oscillating combustion of the gas burners in the combustion chamber and thereby dissipates that vibration and noise.
Patent CA-2135058-A1 (CA)
Title: Seal making device
Inventor: KAMEDA TAKANOBU
IPC: G03F7/00
Filed: 1994-03-15
Abstract: ABSTRACT      An object of the present invention is to provide a seal making device, by which any other person other than a specialist can make a desired seal, door plate, name plate or the like easily and quickly.    The seal making device of the present invention employs a resin member 42b on which an imprint figure is formed, and in which a part thereof physically stimulated by  ultraviolet,  laser  beam,  heat  or  the  like  has characteristics different from those of another part and one of the parts can be removed by the action of a predetermined kind of fluid,     Further,  in the seal making device, as an imprint figure transfer controlling unit 20 controls an imprint figure writing unit as to whether or not a physical stimulation should be givin to each minute unit area on a surface of the resin member according to an imprint figure read by an information processing unit, the imprint figure writing unit applies on  the  surface  of  the  resin  member  the  physical stimulation  corresponding  to  the  imprint  figure  to thereby partially change characteristics of the resin member.   Thereafter, the part of the resin member having changed in characteristics thereof, or the remaining part of the resin member is removed by using water or the like.    Consequently,  a seal or a reliof or intaglio figure  plate  engraved  with  the  desired  figure  is obtained.
Patent CA-2135155-A1 (CA)
Inventor: LEE YONG W
IPC: G11B23/34
Filed: 1994-11-04
Abstract: A "Karaoke" entertainment system, which permits performers to sing along with a prerecorded musical accompaniment, comprises a tape player, an amplifier unit and a prompting device. The tape player plays tapes prerecorded with an audio accompaniment and a synchronous prompt signal, the latter for generating characters for display as a prompt. The amplifier unit demodulates the prompt signal to provide a character generation signal and supplies it to the promptingdevice. Also, it mixes the audio accompaniment with the voice signal from the performer's microphone, amplifies the combined signal and supplies it to a loudspeaker. The prompting device, which mounts upon the conventional stick microphone, comprises a controller, a port for receiving a character generation signal, a memory and a display unit. The controller buffers the character generation signal in memory and then transfer it to the display to display lines of text which scroll across the display in synchronism with the musical accompaniment signal. A "Karaoke" amplifier unit for use with the prompting device may have a demodulator for extracting a clock signal and strobe signal from the prerecorded prompt signal and supplying them, with the character generation signal, to the prompting device by way of a serial interface. The prompting device can be used independently, in which case the prompt signal may be loaded into the memory before a performance and transferred to the display during the performance, the scroll rate being controlled by the performer using pushbutton switches.