baber/WOPTO huggingface dataset:
Patent CA-2506625-A1 (CA)
Title: Autocrine growth factor receptor antibodies and methods
Inventor: SERRERO GINETTE
IPC: C07K16/28
Filed: 2003-11-18
Abstract: Antitumor compositions and methods of interfering with the biological activi ty of PC cell derived growth factor (PCDGF), anti-PCDGF receptor antibodies, fragments thereof, and methods of malung anti-PCDGF receptor antibodies. The methods involve inhibiting the proliferation of tumor cells expressing the PCDGF receptor by contacting the surface of the cell with anti-PCDGF recepto r antibodies. Anti-PCDGF receptor antibodies are capable of binding to the surface of a cell and interfering with the binding of PCDGF to its receptor. Also provided are compositions comprising anti-PCDGF receptor antibodies and cytotoxic molecules (e.g., toxins, oncotoxins, mitotoxins, immunotoxins, and antisense oligonucleotides). The invention also provides methods of diagnosi ng tumorigenicity by measuring the level of PCDGF receptor in a tumorigencic tissue specimen or biological fluid.
Patent CA-2510119-A1 (CA)
Inventor: OBEREGGER WERNER
IPC: A61K9/24
Filed: 2005-06-17
Abstract: The present invention relates to a modified release composition of at least one form of venlafaxine, which is a delayed controlled release composition. The composition comprises a core comprising at least one form of venlafaxine selected from the group consisting of venlafaxine, an active metabolite of venlafaxine, a pharmaceutically acceptable salt of venlafaxine, a pharmaceutically acceptable salt of an active metabolite of venlafaxine, and combinations Thereof, less than 10% of a gelling agent and a pharmaceutically acceptable excipient. The composition further comprises a modified release coating which substantially surrounds the core which provides a delayed controlled release of the at least one form of venlafaxine.
Patent CA-2511895-A1 (CA)
Inventor: DUBOIS PHILIPPE
IPC: B27K3/15
Filed: 2004-02-11
Abstract: A method of treatment of an element in wood, preferably vertical (defined as cut in the natural direction of growth, transversally to the direction of the fibers) comprising an impregnation stage and a crosslinking stage using a crosslinking agent to produce a water-insoluble reaction product within the wood in which both stages are carried out in a single impregnation bath : Independent claims are included for a wooden element obtained by the claimed method and for the impregnation bath used in the method.
Patent CA-2515117-A1 (CA)
Inventor: JENSEN ROBERT L JR
IPC: A41D13/01
Filed: 2004-01-23
Abstract: Protective garments (120) such as firefighters' coats and pants are described.  The garments (120) have an outer shell material made from substantially non-overlapping panels (122, 124) stitched together. Some panels (122) are specially designed and reserved for carrying an enhanced visibility material (126) on a majority of their exposed surface area. The enhanced visibility material (126) can be a retroreflective material such as an exposed lens beaded construction, a fluorescent material, or a phosphorescent material. The enhanced visibility panel (s) (122) are stitched to non-enhanced visibility panels (124) so that if damaged, the stitch (125a, 125b) can be removed and the enhanced visibility panel (122) replaced to repair the garment (120).
Patent CA-2515706-A1 (CA)
Title: 2-aminoethyl substituted pyrimidin-2-ones, cyclopropanes, pyrazolines, pyrimidines and benzothiazepines and their use as urotensin ii and somatostatin 5 receptor ligands
Inventor: OLSSON ROGER
IPC: C07D281/10
Filed: 2004-02-18
Abstract: The present invention provides a combinatorial approach to a library of novel compounds having four diversity points. The compounds provide for the mapping of urotensin II and somatostatin 5 receptors by differential binding of said receptors. Accordingly, the invention relates in a first aspect to novel compounds of the general formula I to V or salts thereof, The present invention further relates to a method of treating diseases for which modulation of the urotensin II receptor produces a physiologically beneficial response in said disease, such as those associated with CNS function and cardiovascular diseases. The present invention further relates to pharmaceutical compositions comprising these agents for the -treatment of these diseases adapted to modulate the urotensin II receptor.
Patent CA-2516751-A1 (CA)
Title: Pulse detonation system for a gas turbine engine having multiple spools
Inventor: BUTLER LAWRENCE
IPC: F02C5/02
Filed: 2005-08-18
Abstract: A gas turbine engine (10, 110) having a longitudinal centerline axis (12, 112) therethrough, including: a fan section (20, 120) at a forward end of the gas turbine engine (10, 110) including at least a first fan blade row (44, 144) connected to a first drive shaft (32, 132); a booster compressor (28, 128) positioned downstream of the fan section (20, 120), the booster compressor (28, 128) including a first compressor blade row (30) and a second compressor blade row (34) connected to a second drive shaft (33, 133) and interdigitated with the first compressor blade row (30);  and, a pulse detonation system (46, 146) for powering the first and second drive shafts (32, 33, 132, 133). The pulse detonation system (46, 146) powers only the second drive shaft (33, 133) during a first designated condition of the gas turbine engine (10, 110) and both the first drive shaft (32, 132) and the second drive shaft (33, 133) during a second designated condition of the gas turbine engine (10, 110). The first and second drive shafts (32, 33, 132, 133) are powered independently of each other by the pulse detonation system (46, 146).
Patent CA-2518977-A1 (CA)
Title: Delivery device for mineral water bottle counter charges
Inventor: CHENEL JOSEPH MICHEL DONALD
IPC: B65D71/46
Filed: 2005-09-09
Abstract: The invention relates to a delivery device designed to carry Mineral Water Bottle (MWB) counter charges, by remote means, to a target Improvised Explosive Device (IED) during render-safe procedures. The delivery device is die-cut as a blank and folded into the desired form. The device includes at least one elongated tubular holding element for receiving a MWB counter charge with a lifting strap attached thereto that can easily be grasped by any remote means. The device is designed in such a way so as to provide automatic positioning of the MWB counter charges at the appropriate stand-off distance in relation to the IED. As well, the delivery device is fully collapsible so as to facilitate the storage and transportation of the device, and provides a quick and user-friendly system that facilitates the deployment of MWB counter charges.
Patent CA-2519321-A1 (CA)
Title: A device for protecting medical apparatus
Inventor: NERI ROBERTO
IPC: B01D46/54
Filed: 2004-03-16
Abstract: A device for protecting medical apparatus from contamination by infectious agents comprises a containment body having an inlet (5) destined to be set in fluid communication with an extracorporeal circuit (3) of blood, and an outlet (6) destined to be connected to a fluid line operatively connected to a pressure gauge of a medical apparatus (4). The inlet (5) is in gas communication with the outlet (6) across an internal cavity (11) of the containment body. Two hydrophobic membranes (12, 13) are predisposed in the containment body between the inlet (5) and the outlet (6). The membranes (12, 13) each define an anticontamination barrier which is gas-permeable. The device transmits the pressure of the extracorporeal circuit to the pressure gauge, with no relevant loss of head, while at the same time protecting, with a high degree of security, the medical apparatus (4) from risks of contamination by pathogens originating in the extracorporeal circuit.
Patent CA-2520847-A1 (CA)
Inventor: DIEHL STEFAN
IPC: B66C23/90
Filed: 2004-03-26
Abstract: Method for erecting and disassembling an at least two- piece main boom for a lattice-boom crane. The erecting and disassembling procedure results in that the geometric kinematic properties of the main boom (1, 2) are used in such a manner that during the erecting and disassembling, the effective lever arm (1 ') of the main boom (1, 2) is reduced, to prevent tipping of the crane. The main boom (1, 2) is bent at the hinge point (A), at which at least two boom portions (1, 2) are connected to each other, and thus an angle position is produced between the two boom portions (1, 2). When the lever arm is within acceptable limits, the boomis raised, after which the boom sections are aligned and locked. Also disclosed are a boom and crane with such a boom.
Patent CA-2521316-A1 (CA)
Title: Mass spectrometer with axial ejection and with rod geometry for generating a two-dimensional quadrupole field with added octopole component and method of operating the same
Inventor: SUDAKOV MIKHAIL
IPC: G01N27/62
Filed: 2004-04-13
Abstract: A mass spectrometer (210) having an elongated rod set (238), and a method of operating same. The rod set has an entrance end, an exit end and a longitudinal axis. Ions are admitted into the entrance end of the rod set. At least some of the ions are trapped in the rod set by producing a barrier field at an exit member (242) adjacent to the exit end of the rod set and by producing an RF field between the rods of the rod set adjacent at least the exit end of the rod set. The RF and barrier fields interact in an extraction region adjacent to the exit end of the rod set to produce a fringing field.  Ions in the extraction region are energized to mass selectively eject at least some ions of a selected mass to charge ratio axially from the rod set past the barrier field. The RF field is a two-dimensional substantially quadrupole field having a quadrupole harmonic with amplitude A2, an octopole harmonic with amplitude A2, and a hexadecapole harmonic with amplitude A8. A8 is less than A4, and A4 is greater than 0.1% of A2.
Patent CA-2522941-A1 (CA)
Title: Improved methods and solutions for storing donor organs
Inventor: TOLEDO-PEREYRA LUIS
IPC: A01N1/00
Filed: 2004-04-22
Abstract: A method of preserving, storing and transplanting mammalian donor organs. The method includes the cooling of refrigeration preservation, loading pre-freezer preservation, cryopreservation and washing solutions at least containing polyvinylpyrrolidone, a calcium channel blocker, a nucleoside, potassium chloride, polyethylene glycol, at least one amino acid, and a steroid to a temperature of 2~ to 4~ C and/or of 0~ to 2~ C, harvesting a donor organ, perfusing it with one or more of the solution, immersing it in one or more of the solutions and storing it at a temperature above 0~ C or at a temperatures below 0~ C. The cryopreservation solution also contains cryopreservative agents. Preserved organs may be transplanted directly from refrigeration storage or from freezer storage by cooling the washing refrigeration preservation solutions to 2~ to 4~ C, perfusing the organ with washing solution and then preservation solution, and transplanting it.
Patent CA-2523704-A1 (CA)
Title: Process for converting a hydrocarbon to an oxygenate or a nitrile
Inventor: BROPHY JOHN H
IPC: C07C45/33
Filed: 2004-04-27
Abstract: This invention relates to a process for converting a hydrocarbon reactant to a product comprising an oxygenate or a nitrile, the process comprising: (A) flowing a reactant composition comprising the hydrocarbon reactant, and oxygen or a source of oxygen, and optionally ammonia, through a microchannel reactor in contact with a catalyst to convert the hydrocarbon reactant to the product, the hydrocarbon reactant undergoing an exothermic reaction in the microchannel reactor; (B) transferring heat from the microchannel reactor to a heat exchanger during step (A); and (C) quenching the product from step (A).
Patent CA-2524492-A1 (CA)
Inventor: LEE INMOK
IPC: C11C1/04
Filed: 2004-06-10
Abstract: This invention relates to a method of hydrolyzing glycerol fatty acid ester-containing composition, such as a fat and/or an oil, to produce fatty acids having a low proportion of trans-isomer fatty acids. Specifically, the present invention relates to a process for the hydrolyzing the glycerol fatty acid ester-containing compositions under conditions resulting in a low proportion of trans-isomer fatty acids.
Patent CA-2525478-A1 (CA)
Inventor: HUXFORD ROGER BRIAN
IPC: H04N9/31
Filed: 2004-04-21
Abstract: Image display apparatus comprising projector means, at least one primary modulator (4, 6, 8) for modulating light, an auxiliary modulator (36) for modulating the light modulated by the primary modulator, and optical means (32) for relaying the light modulated by the primary modulator to the auxiliary modulator (36), the optical means (32) comprising a concave mirror and at least one refractive element.
Patent CA-2526136-A1 (CA)
Title: Gaming system having selective synchronized multiple video streams for composite display at the gaming machine
Inventor: CRAM MARC
IPC: G06F17/00
Filed: 2004-05-21
Abstract: A slot machine (13) has a display area (31) with a background image (49) and simulated reels (37). The simulated reels (37) are color-coordinated with the background image (49) and some symbols on the reels (45, 47) illustrate a theme that coordinates with the background image (49).
Patent CA-2528145-A1 (CA)
Inventor: SCOTT HAROLD
IPC: B60L50/10
Filed: 2004-06-02
Abstract: The invention is a control system that, among other things, controls a permanent magnet alternator and provides relatively accurate voltage regulation. The control system may include one or more of the following: (1) a rectification system to rectify and regulate the output voltage of an alternator, (2) a rectifier/limiter used as an electrical power source to a boost type regulator, (3) a multimode rectifier/limiter, (4) a DC to AC  inverter bridge, and (5) power switches employed in the system to minimize the switching energy that would otherwise be dissipated in the power switches as heat.
Patent CA-2528273-A1 (CA)
Title: Hydrophilic adhesive compositions for delivery of herbal medicines
Inventor: LU LING
IPC: A61L15/44
Filed: 2004-05-21
Abstract: A hydrophilic, pressure-sensitive adhesive composition comprising a swellable adhesive polymer, a swelling agent, herbal medicines, and optionally a modifying polymer in an amount sufficient to form a cohesive, pressure-sensitive adhesive composition. The composition is useful as a delivery device for herbal medicine and other active ingredients to or through skin. A method of preparation of the composition is also disclosed.
Patent CA-2528476-A1 (CA)
Title: Exercise apparatus using weight and pneumatic resistances
Inventor: PETERSON WADE A
IPC: A63B21/00
Filed: 2004-06-28
Abstract: An exercise apparatus combines weight and pneumatic resisitance to provide a user with options to work against either or both type of the resistances. In one mode, the exercise apparatus includes a user interface, such as, for example, a weight-lifting bar, that a user can move either toward or away fr om stationary portion of the user~s body. A weight (e,g., a free weight plate) can be selectively coupled to the user interface. A pneumatic resistance device can also be selectively coupled to the user interface independent of whether the user interface is also coupled to the weight. The pneumatic resistance device includes at least one valve to regulate the amount of the resistance that the pnuematic resistance device applies to oppose movement o f the user interface in at least one direction. At least one actuator may be provided for controlling the at least one valve, the actuator being configur ed to be manipulated by the user while the user is in an exercise position. The apparatus can also include a trolley that moves relative to a track. The trolley can move with the user interface so as to permit various positions o f the user interface relative to the pneumatic resistance device. An adjustabl e bench adapted to support the user during exercise and capable of engaging an auxilliary rackassembly may also be provided. The bench includes a seat and a backrest that are interconnected and moveable relative to a frame. The bench is adjustble from a generally flat configuration to one or more inclined configurations. In the Flat configurations, the bench is particularly suitab le for pressing exercise such as the bench press. In the fully inclined positio n, the bench is suitable for upright exercise such as the military press and th e shoulder press. The shoulder of the human body remain generally at the same horizontal location along the bench as the backrest is inclined. The bench thus does not need to be repositioned relative to a bar as the inclination o f the bench is changed.
Patent CA-2529838-A1 (CA)
Inventor: THOMPSON JOHN E
IPC: C12N9/02
Filed: 2004-06-21
Abstract: The present invention relates to unique isoforms of eukaryotic initiation Factor 5A ("eIF-5A"): senescence-induced eIF-5A; wounding-induced eIF-5A; and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the expression of these factors. The present invention also relates to deoxyhypusine synthase ("DHS"), polynucleotides that encode DHS, and methods involving modulating the expression of DHS.
Patent CA-2530115-A1 (CA)
Inventor: RUTTER NICHOLAS ALEXANDER
IPC: G08B21/12
Filed: 2003-06-24
Abstract: An alarm for detecting radiation and/or pollutants such as smoke, carbon monoxide or the like has a housing (500), an alarm circuit (400) including a detector (DET1) for detecting said radiation and/or pollutants, first electrical connections (PL1, PL2) connectable to an external power supply for supplying power to the alarm circuit, and a control circuit (300) responsive to receipt of a preselected number of pulses over a preselected time period to apply a preset control signal to the alarm circuit (400). The alarm circuit (400) is responsive to the preset control signal to reset or test the alarm in dependence on the preset control signal.
Patent CA-2531707-A1 (CA)
Inventor: MERETEI ATTILA
IPC: A61M25/00
Filed: 2005-12-28
Abstract: Systems and methods for treating an occluding thrombus in a blood vessel of a patient. Ferrofluids having magnetic particles dispersed therein are introduced locally via a catheter, a micro-catheter, or intravenously, to the bloodstream of a patient. The ferrofluids are magnetically manipulated or moved throughout the blood vessels of the patient by an external magnetic field generator until the intended occluding thrombus is broken up and removed. The external magnetic field generator, which can be stationary or portable, creates a vortex, high velocity jets, or other motion, within the ferrofluids, by rotating or moving at least one magnet relative to the patient.      The at least one magnet is provided in the magnetic field generator. The vortex, high velocity jets, or other motion of the ferrofluids are used to break-up and remove the occluding thrombus. Drugs or abrasive particles, or both, may be incorporated with the ferrofluids and delivered to the bloodstream with the ferrofluids to help break-up and remove the occluding thrombus as well. Upon removal of the thrombus, magnetic components of the ferrofluids may remain in the patient or may be magnetically recaptured and removed from the bloodstream.
Patent CA-2532873-A1 (CA)
Inventor: LABROUSSE LAURENT
IPC: C03C17/245
Filed: 2004-07-21
Abstract: L~invention a trait à un procédé de préparation d~un matériau à propriétés photocatalytiques comprenant de l~oxyde de titane au moins partiellement cristallisé, notamment sous forme anatase, mettant en .oelig.uvre des températures excédant 600~ C. L~invention concerne également une feuille de verre dont une face au moins porte un revêtement d~un matériau comprenant de l~oxyde de titane, qui est apte à être ou a été soumise à un traitement thermique à plus de 600~ C tel que de trempe et/ou bombage, tout en préserva nt l~activité photocatalytique et la qualité optique requises pour un vitrage anti-salissure. L~invention a également pour objet un vitrage monolithique, feuilleté, simple ou multiple comprenant une telle feuille de verre, et l~application de ce vitrage pour le bâtiment, un véhicule de transport, comm e vitrage utilitaire, d~ameublement intérieur, de mobilier urbain, miroir, écr an de système d~affichage, vitrage photovoltaïque.
Patent CA-2533232-A1 (CA)
Title: Sediment control
Inventor: MCGINN JOHN H
IPC: E02B8/02
Filed: 2006-01-19
Abstract: Sediment collection devices (SCDs) which can be used to collect sediment from sediment-bearing liquid, for example runoff from construction sites, and which have improved durability, particularly when wheeled vehicles pass over them. The SCDs include a horizontal location member; and a generally vertical member comprising (1) a filter which has relatively small apertures therethrough, and (2) threshold and outflow members each of which have relatively large apertures therethrough and which together provide a sediment control chamber (SCC) between them. The height of the SCC  is at least 1.5 times its width; and/or the SCC is shaped so that a vehicle wheel approaching the SCD contacts the SCD at a defined height and angle; and/or one or both of the threshold member and the outflow member has a bending or stiffening line such that different parts of the SCD respond differently to bending forces. Precursors and methods for making such SCDs are described.
Patent CA-2533353-A1 (CA)
Title: Percutaneous heart valve
Inventor: ANANTHASURESH SURESH G K
IPC: A61F/
Filed: 2004-07-20
Abstract: A percutaneously inserted bistable heart valve prosthesis (10) is folded inside a catheter for transseptal delivery to the patient's heart for implantation. The heart valve (10) has an annular ring (12), a body member (14) having a plurality of legs (16), each leg (16) connecting at one end to the annular ring (12), claws (18) that are adjustable from a first position to a second position by application of external force so as to allow ingress of surrounding heart tissue into the claws (18) in the second position, and leaflet membranes connected to the annular ring (12), the body member (14) and/or the legs (16), the leaflet membranes having a first position for blocking blood flow therethrough and a second position for allowing blood flow therethrough. The heart valve (10) is designed such that upon removal of the external force the claws (18) elastically revert to the first position so as to grip the heart tissue positioned within the claws (18), thereby holding the heart valve (10) in place.. The heart valve (10) may be used as a prosthesis for the mitral valve, aortic valve, pulmonary valve, or tricuspid valve by adapting the annular ring to fit in a respective mitral, aortic, pulmonary, or tricuspid valve opening of the heart.
Patent CA-2534553-A1 (CA)
Title: Interlaminar vertebral prosthesis
Inventor: DENEUVILLIERS GUY
IPC: A61B17/88
Filed: 2004-03-24
Abstract: The prosthesis comprises an elastic body (1) inserted between two adjacent vertebrae (L2, L3) against the laminar arch (A2, A3) of each vertebra and means (3, 5) for securing the elastic body to said laminar arches.
Patent CA-2535645-A1 (CA)
Title: Therapeutic immunization of hiv-infected individuals
Inventor: SHIVER JOHN W
IPC: A61K39/00
Filed: 2004-09-14
Abstract: The present invention provides an improved method for eliciting a therapeutic immune response in an individual infected with human immunodeficiency virus (~HIV~). The method comprises administering an adenoviral vaccine composition expressing an HIV antigen to an individual with controlled viremia.  Immunization of infected individuals in this manner elicits a cellular-mediated immune response against the virus that is significant both in the level of the response and the breadth of the response. The therapeutic immune response that ensues is capable of effectively maintaining low titers of virus and, thus, offers the prospect of reducing individual dependency on antiviral therapy.