baber/WOPTO huggingface dataset:
Patent DK-174253-B1 (DK)
Title: Vaccinia virus modified with exogenous DNA in vaccinia genome - useful for vaccination of animals to form antibodies to coded antigens
Inventor: PAOLETTI ENZO
IPC: C12N15/00
Filed: 1997-09-24
Granted: 2002-10-21
Abstract: Vaccinia virus modified by the presence of exogenous DNA in the vaccinia genome is new. Biologically pure cultures of vaccinia virus VTK-79 (ATCC VR 2031) and VTK-79L are new. Immunisation of a host animal susceptible to vaccinia virus is effected by inoculation with a vaccinia virus having, within the vaccinia genome, DNA exogenous to the genome and coding for an antigen that will induce the animal to develop antibodies against it. Method for the in vivo recombination of a vaccinia virus and donor DNA comprises contact of a cell monolayer with a cell-compatible medium contg. the vaccinia virus and with a similar medium contg. the donor DNA. The donor DNA comprises DNA to be introduced into the vaccinia genome present in a DNA segment otherwise co-linear with DNA present in the genome of the virus in a non-essential region of the genome. Vaccines contg. the modified virus can be used to immunise mammals so that an approp. antibody response is elicited. Lukaryotic cells of biological prods. other than antigens can be produced. Human and animal individuals and populations may have missing genes or genetic material (for modification, replacement or repair of defective genes) introduced.
Patent DK-171049-B1 (DK)
Inventor: HANSEN SONJA MARIANNE JUEL
IPC: A61G9/00
Filed: 1991-06-27
Granted: 1996-05-06
Abstract: A plastic bag (2) or the like is temporarily fastened in an upwardly open container (1), such as a bed pan, by means of an adhesive coating (3) applied between the container (1) and the plastic bag (2). The coating (3) adheres strongly to the plastic bag (2) and faintly to the container (1). The device may be formed as a double-adhering foil with at least one grasping tab.
Patent DK-172753-B1 (DK)
Inventor: SHIH CHUAN
IPC: A61K31/505
Filed: 1989-05-02
Granted: 1999-06-28
Abstract: A compound selected from the group consisting of a glutamic acid derivative of the formula: <CHEM>  in which:  R<1> is -OH or -NH2;  R<2> is hydrogen or a carboxy protecting group; R<3> is a carbon-carbon bond, alkylene of 1 to 4 carbon atoms, cyclohexylene, or <CHEM>  R<4> is hydrogen or an amino protecting group;  Q is -S- or -O-;  R<5> is hydrogen, chloro or fluoro; and  the configuration about the carbon atom designated * is S; and the pharmaceutically acceptable salts thereof. Also disclosed is a method of combatting neoplastic growth in a mammal and a pharmaceutical composition for combatting neoplastic growth in a mammal making use of the above compound.
Patent DK-175130-B1 (DK)
Inventor: HEAFIELD JOANNE
IPC: A61K31/52
Filed: 1989-06-01
Granted: 2004-06-14
Abstract: A controlled release, solid, oral dosage form containing a 3-alkylxanthine, preferably theophylline, at least one hydrophilic or hydrophobic polymer, at least one wax having a melting point between 25 DEG  and 90 DEG C and between 3% and 10% (by weight) water. Preferably the dosage form is a tablet and the water content is between 4% and 9% (by weight). The amount of water present in the dosage form determines the rate of release of the 3-alkylxanthine.
Patent DK-173687-B1 (DK)
Inventor: ZIEGELMAIER ROBERT
IPC: G01N33/543
Filed: 1988-05-20
Granted: 2001-06-25
Abstract: The immunoassay entails a solid phase to which antibodies against the immunoglobulin class, or a fragment of an antibody of this type, are bound being contacted with an immunoglobulin-containing fluid, resulting in the immunoglobulin of this class being bound to this solid phase, and this solid phase being contacted with the antigen which optionally carries a label, and with a labelled antibody or a labelled fragment of an antibody against the antigen, if the antigen is unlabelled, and the amount of these antibodies which are specific for an antigen from one of the immunoglobulin classes being determined from the amount of label bound to the solid phase, and is characterised in that the solid phase is simultaneously in contact with the fluid containing the antibodies to be determined and with the optionally labelled antigen, and a substance which prevents immunoglobulin G binding to the solid phase, and, where appropriate, antigen binding to immunoglobulin G is added.
Patent DK-173185-B1 (DK)
Inventor: IRIKURA TSUTOMU
IPC: C07D215/56
Filed: 1985-11-12
Granted: 2000-03-06
Abstract: Quinolonecarboxylic acid derivatives of the following formula, <CHEM> wherein R, R<1> and R<2> are each independently hydrogen atom or lower alkyl group and Y is hydrogen atom or halogen atom; the hydrates and pharmaceutically acceptable salts thereof are useful as antibacterial agents.
Patent IE-55239-B1 (IE)
Title: Fixings including screws and clamp plates
IPC: F16B35/04
Filed: 1984-06-14
Abstract: A fixing for fixing a waterproof membrane 6 and an insulation material 4 to a steel sheet 2 consists of a clamp plate 8 and a screw 10. The screw 10 comprises a head 11, a shank, and a drilling tip 14. The head 11 has a clamping face 12 which tapers towards the shank, and which has external angles 30 in cross section. The shank has, in succession from the head 11 to the drilling tip 14, a first portion 16 which is unthreaded, a second portion 18 which is threaded, and a third portion 22 which is threaded. The diameter of the first portion 16 is approximately the root diameter of the second portion 18, and the crest diameter of the second portion 18 substantially exceeds the crest diameter of the third portion 22. The clamp plate 8 is formed from sheet metal and has a central hole 24. The periphery of the clamp plate 8 is of elongate symmertrical shape having a minor dimension which is several times the diameter of the hole 24 and a major dimension substantially greater than the minor dimension. The clamp plate is generally flat with a countersink 28 around the hole 24, and with two endless gutter-like deformations 34, 36, the first one 34 adjacent the periphery, and the second one 36 approximately midway between the hole 24 and the first one 34.
Patent IE-56756-B1 (IE)
Title: Flow control device for administration of intravenous fluids
IPC: F16K5/10
Filed: 1985-06-24
Abstract: A metering apparatus and system for controlling the administration of IV fluids having a valve housing (14, 60, 102, 202, 302, 505, 602) with a valving chamber therein. A rotatable valve body member (40, 80, 125, 220, 322, 502, 618) is positioned within the valve chamber and a valve passageway of variable cross-sectional area is provided at either the chamber (330) or on the valve member (64, 90, 140, 242, 509, 620). The effective area and length of the valve passageway interposed between the inlet and outlet to the valve is adjustable to regulate flow by moving the valve body relative to the valve member. Various accessories can be selectively attached to the basic valve configuration including a backplate (150, 510) which facilitates single-handed operation and an optional cover plate (550) which may be secured to the backplate (510) to provide security from patient tampering. In the preferred embodiment the valve housing and internal valve members are fabricated from dissimilar plastic materials of different hardness to improve the sealing therebetween.
Patent IE-53493-B1 (IE)
Title: New derivatives of pyridazine active on the central nervous system
IPC: C07D237/20
Filed: 1982-07-28
Abstract: The present invention relates to derivatives of pyridazine of formula: <IMAGE> (I) in which R1 is alkyl or a phenyl group and R2 is H or R1 and R2 form, with the carbon atoms to which they are attached, a benzene cycle, R3 is H or phenyl and R4 is <IMAGE> in which R5 is H or CH3 and R6 is H, OH, OR or OCOR; it also relates to a process for preparing the products of formula (I) and to the drugs containing at least one of said products.
[US4710499A]
Patent IE-50268-B1 (IE)
Title: 2-amino-3-benzoyl-phenylacetamides and cyclic homologues
Inventor: SHANKLIN J R
IPC: C07C323/32
Filed: 1980-09-17
Abstract: 2-Amino-3-benzoyl-phenylacetamides are provided having the formula:  wherein: R represent hydrogen or lower alkyl, R<1> and R<2> represent hydrogen, lower alkyl, cycloalkyl, phenyl and phenyl substituted by lower alkyl, lower alkoxy, halogen, nitro and trifluoromethyl, and R<1> and R<2> when taken together with the adjacent nitrogen may form a heterocyclic residue; X represents hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl; Y represents hydrogen, lower alkyl, lower alkoxy, halogen, trifluoromethyl, lower alkylthio, lower alkyloxythio or lower alkyldioxythio; Am is primary amino (-NH2), methylamino or dimethylamino, and n is 1 to 2 inclusive. The compounds exhibit anti- inflammatory, antipyretic, anti-blood platelet aggregation and analgetic pharmacological activities.
Patent IE-46215-B1 (IE)
Title: Production of specific immune nucleic acids cell dialysates and antibodies
IPC: C12N5/071
Filed: 1977-12-14
Abstract: Gamma-globulins and immune nucleic acids, both specific to a given antigen, are produced by culturing in vitro an inducible cell line in the presence of specific immune nucleic acids or specific immune dialysates obtained either from human or animal donor lymphoid cells sensitized to said specific antigen or from cells of a previously induced cell line sensitized to said specific antigen, or in the presence of the liquid phase of a culture of a previously induced cell line sensitized to said specific antigen; and extracting gamma-globulins from the liquid phase of the thus induced cell culture and/or extracting the immune nucleic acids from the cells so cultured. Specific immune dialysates may also be produced by a similar process.
Patent IE-54813-B1 (IE)
Title: Microorganism actinomadura yumaense sp.nov. and use thereof to prepare antibiotics ll-c23024 alpha, beta and iota
IPC: C12R1/03
Filed: 1982-10-21
Abstract: Antibiotic LL-C23024 alpha , or a pharmaceutically acceptable salt thereof, or a fermentation broth or harvest mash solid from which the antibiotic is obtained, is used to control nematodes in warm-blooded animals or in the soil.
[GB2147808A]
Patent IE-60785-B1 (IE)
Title: Controlled release dosage form
IPC: A61K9/54
Filed: 1988-10-26
Abstract: A controlled release dosage form which consists essentially of a core containing a medicament; an inner coating layer composed of ethylcellulose and a hydrophobic substance; and an outer coating layer containing a medicament are disclosed. Said dosage form shows rapid increase in blood concentration of the medicament and at the same time maintains the high level of the blood concentration over a prolonged period time.
Patent IE-67546-B1 (IE)
Title: Needle Assembly
Inventor: SWEENEY NIAL
IPC: A61M5/32
Filed: 1990-11-15
Abstract: A needle assembly (20) includes an elongate cannula (21) having a first end (34), an opposite end (35) and a sidewall (37) therebetween. The cannula includes a lumen therethrough defining a cannula longitudinal axis (39). A hub (22) having a proximal end (40), a distal end (41) and a passageway (43) therethrough defining a longitudinal axis (44) is provided. The passageway (43) includes an enlarged first portion (45) at the distal end, a second portion (46) adjacent to the first portion (45) and a third portion (47) adjacent to the proximal end. The cannula (21) is positioned in the hub (22) so that the opposite end (35) is within the second portion (46) and the first end (34) projects outwardly from the distal end (41) of the hub (22). The second portion (46) includes a proximally located ledge (49) for establishing the most proximal position of the cannula (21) in the passageway (43) and an inwardly projecting flange (51), located distally from the ledge (44), for contacting and holding a cannula (21) with sufficient force to prevent the cannula (21) from falling out of the hub (22). The annular flange (51) and the ledge (49) interact with the cannula (21) so that the angular relationship between the cannula (21) longitudinal axis and the hub (22) longitudinal axis can be varied and the cannula (21) movably held in a selected angular relationship. Adhesive (23) is provided in the volume described by the first portion for holding the cannula (21) fixedly in the selected angular relationship with respect to the hub (22). <IMAGE>
Patent IE-69861-B1 (IE)
Title: NADH and MADPH as energy substitutes
Inventor: BIRKMAYER JOERG
IPC: A23L1/30
Filed: 1992-01-23
Abstract: Use is described of nicotinamide adenine dinucleotide in its reduced form (NADH) and/or nicotinamide adenine dinucleotide phosphate in its reduced form (NADPH) and/or a physiologically tolerated salt of the same for energy substitution in humans or animals, as is a foodstuff or confectionary product for human consumption or a feedstuff for animal consumption having a content of the substances mentioned.
Patent LU-101483-B1 (LU)
Title: Coal liquefaction device and process
Inventor: ZHANG MINGXU
IPC: F16K17/196
Filed: 2019-11-18
Granted: 2021-02-04
Abstract: The present invention relates to the technical field of coal liquefaction, and in particular, discloses a coal liquefaction device and process. The coal liquefaction device includes a gas storage tank for storing an inert gas, where both ends of the gas storage tank are provided with pulverized coal storage tanks, a first connecting pipe for connecting the gas storage tank to the pulverized coal storage tank is disposed between the pulverized coal storage tank and the gas storage tank, and a pumping mechanism for conveying gases in the gas storage tank and the pulverized coal storage tank is disposed on the first connecting pipe; a gasification furnace is disposed below the gas storage tank, a second connecting pipe for connecting the pulverized coal storage tank to the gasification furnace is disposed between the pulverized coal storage tank and the gasification furnace, and the second connecting pipe is provided with a first valve. According to the present invention, the coal liquefaction device can continuously add pulverized coal to the gasification furnace, and also avoids the discharge of the inert gas into the air, thereby reducing production cost and avoiding environmental pollution.
Patent LU-102852-B1 (LU)
Title: Process for continuous extraction of lignocellulosic material
Inventor: CONRAD Marc
IPC: D21C3/20
Filed: 2021-08-02
Granted: 2023-02-02
Abstract: The invention provides a process for continuous extraction of lignocellulosic material, the process comprising at least one stage comprising the steps of a) conveying the lignocellulosic material into an extractor, b) forming, in the extractor, a suspension of the lignocellulosic material and a solvent, c) extracting the lignocellulosic material in the extractor with the solvent, d) withdrawing part of the suspension from the extractor and conveying it to a pressing device at a flow rate m4, e) separating the solvent from the lignocellulosic material by pressing off the solvent from the lignocellulosic material in the pressing device and conveying pressed-off solvent as a pressate to a pressate tank at a flow rate rh7, f) withdrawing pressed lignocellulosic material from the pressing device at a flow rate rh6, g) returning a first part of the pressate from the pressate tank at a flow rate rh8 into the extractor, h) withdrawing a second part of the pressate as an extract from the pressate tank at a flow rate rh9, i) Adding solvent to the lignocellulosic material in any one or more of steps a, b, c, d, e or g at a flow rate m2.
Patent LU-501348-B1 (LU)
Title: Method for constructing large-span thin-walled concrete sound barrier with pouring trolley
Inventor: FU QIANG
IPC: E01F8/00
Filed: 2021-06-24
Granted: 2022-08-09
Abstract: The present application relates to a trolley construction method for pouring long span thin wall concrete sound barrier, which includes the following steps: Step 1: constructing a base on two sides of the existing line, and mounting a steel rail on the base; Step 2: hoisting a pre-assembled walking system; Step 3: mounting a truss system, transporting a processed arch frame to a construction site, hoisting the arch frame, connecting a vertical column to the connecting beam, adjusting the lifting jack and a hydro-cylinder, adjusting the arch frame and a turn-over section to a design elevation, mounting the subsequent arch frames successively by repeating the above processes, and connecting a connecting rod between the adjacent arch frames after mounting and adjusting the arch frames; Step 4: mounting a base mold on an arch crown, assembling a reinforcement, mounting a side mold, conducting the pouring of the concrete, curing, lowering the arch frame by the lifting jack and the hydro-cylinder after the concrete reaching the design strength, detaching the base mold, then continuing to adjust the height by the lifting jack until the walking wheel contacts the steel rail, and moving a trolley. The present application is convenient for movement and construction, and has no influence on the passage of existing lines while meeting the construction requirements.
Patent LU-504013-B1 (LU)
Title: An automatic tested device for withstand voltage of insulating tool
Inventor: HU YUTING
IPC: G01R31/12
Filed: 2023-04-20
Granted: 2023-10-20
Abstract: The invention discloses an automatic test device for the withstand voltage of an insulation tool, which comprises a bracket assembly, a test assembly and an electrical connection assembly, wherein the electrical connection assembly is arranged in a circuit assembly and comprises a first electrical connector and a second electrical connector; According to the automatic test device for the withstand voltage of the insulating tool, a plurality of insulating boots or insulating gloves can be subjected to the withstand voltage test at the same time, the leakage current of each test object is measured at a high-voltage side, and when the leakage current of each test object exceeds a setting value, the automatic test device for the withstand voltage of the insulating tool can be automatically tripped, so that the normal test of other test objects is not influenced. Strictly implement the standard to make the test more standardized.
Patent LU-504341-B1 (LU)
Title: Ein physikalisch vernetztes hydrophiles gel mit selbsttragenden und selbstschmierenden eigenschaften sowie dessen herstellungsverfahren
Inventor: CHEN LU
IPC: C08J3/075
Filed: 2023-05-29
Granted: 2023-12-04
Abstract: Die vorliegende Erfindung offenbart ein physikalisch vernetztes Hydrogel mit selbststützenden und selbstschmierenden Eigenschaften sowie ein Herstellungsverfahren dafür. Sie gehört zum Bereich der Hydrogelmaterialien. Das Verfahren umfasst folgende Schritte: Eine homogene Mischungslösung wird hergestellt, indem Gelatine, Polysaccharid-Polymere und oberflächenaktive Stoffe als Rohstoffe verwendet werden. Salze, die eine Hofmeister-Fällungsreaktion mit der Gelatine und eine Komplexbildung mit den Polysaccharid-Polymeren eingehen können, werden einseitig in die Mischungslösung diffundiert, um ein heterogenes erstes und zweites Gelnetzwerk mit einer Gradientenverteilung der Vernetzungsdichte entlang der Diffusionsrichtung der Kationen und Anionen aufzubauen. Das Hydrogel wird eingeweicht, um freie Metallionen zu entfernen und eine stabile Größe zu erreichen. Dadurch entsteht ein physikalisch vernetztes Hydrogel mit selbststützenden und selbstschmierenden Eigenschaften. Durch die Einführung von oberflächenaktiven Stoffen und die Gradientenstruktur der Doppelnetworks weist das Hydrogel hervorragende mechanische Eigenschaften und tribologische Eigenschaften auf, und es überwindet das Problem der geringen Schmiereffizienz bei hochmoduligen Gelen.
Patent NO-303911-B1 (NO)
Inventor: ARKENS CHARLES THOMAS
IPC: D04H1/64
Filed: 1992-04-28
Abstract: A heat-resistant nonwoven is disclosed which comprises a polymer comprising carboxy or carboxylic anhydride groups and  beta -hydroxyalkyl amide or a polymer thereof. The nonwoven can be an asphaltic roofing substrate or a cushioned flooring product.
Patent NO-302663-B1 (NO)
Inventor: BRAUN RUDOLF
IPC: C08G77/12
Filed: 1993-11-30
Abstract: PCT No. PCT/EP92/01252 Sec. 371 Date Jul. 29, 1994 Sec. 102(e) Date Jul. 29, 1994 PCT Filed Jun. 4, 1992 PCT Pub. No. WO92/21724 PCT Pub. Date Dec. 10, 1992.The invention relates to organo(poly)siloxane compositions which have long shelf life in the absence of water, but can be crosslinked in the presence of water, even at room temperature, to give elastomers with elimination of alcohols, and to a process for the preparation of such compositions.
Patent NO-309541-B1 (NO)
Inventor: JANSSEN RUPERT
IPC: F16B19/14
Filed: 1995-09-14
Abstract: The fixing element has a nail (1) which is driven into a hard surface of a stationary component via a nail driver and a cooperating tensioning element (2) having a shaft section (2a) receiving the pointed end of the nail and a mounting flange (2b) abutting the component surface. The tensioning element is enclosed by a plastics element (3) with a bearing surface lying flush with the bearing surface of the tensioning element, which is received in a recess of the plastics element having an inner dia. corresponding to the outer dia. of the tensioning element.
Patent NO-308599-B1 (NO)
Inventor: D AMBRA THOMAS EDWARD
IPC: C07D211/20
Filed: 1995-12-12
Abstract: The invention relates to compounds of the formulae I, II and IX <CHEM>  wherein     R3 is -COOH or -COOR4;   R4 is an alkyl with 1 to 6 carbon atoms; A is the substituents of its ring, each of which may be different or the same, and are selected from the group consisting of hydrogen, halogens, alkyl, hydroxy or alkoxy.   X<+> is a Lewis acid   X is halogen.   The compounds are useful as intermediates and processes for their preparation are also disclosed.
Patent NO-311977-B1 (NO)
Inventor: MACKENZIE ALEXANDER RODERICK
IPC: A61K31/4523
Filed: 1997-02-07
Abstract: PCT No. PCT/EP95/03054 Sec. 371 Date Feb. 10, 1997 Sec. 102(e) Date Feb. 10, 1997 PCT Filed Jul. 29, 1995 PCT Pub. No. WO96/05193 PCT Pub. Date Feb. 22, 1996The present invention provides compounds of formula (I) and the pharmaceutically acceptable salts thereof, wherein R is C3-C7 cycloalkyl, aryl or C1-C6 alkyl, said C1-C6 alkyl, said C1-C6 alkyl being optionally substituted by fluoro, COOH, -COO(C1-C4 alkyl), C3-C7 cycloalkyl, adamantyl, aryl or het1, and said C3-C7 cycloalkyl being optionally substituted by 1 or 2 substituents each independently selected from C1-C4 alkyl, C3-C7 cycloalkyl, C1-C4 alkoxy, hydroxy, fluoro, fluoro (C1-C4) alkyl and fluoro (C1-C4) Alkoxy; R1 is phenyl, naphthyl, thienyl, benzothienyl or indolyl, each optionally substituted by 1 or 2 substituents each independently selected from C1-C4 alkyl, C1-C4 alkoxy, halo and trifluormethyl; R2 is -CO2H, -CONR3R4, -CONR5(C3-C7 cycloalkyl), -NR5(C2-C5 alkanoyl), -NR3R4, -NR5CONR5R6, (C3-C7 cycloalkyl-C1-C4 alkyl)R5N-, -NR5COCF3, -NR5SO2CF3, -NR5(SO2 C1-C4 alkyl), -NR5SO2NR5R6, -NR5(SO2 aryl), -N(aryl) (SO2C1-C4 alkyl), -OR5, -O(C3-C7 cycloalkyl), -SO2NR5R6, het3 or a group of formulas: (a), (b), (c), (d), (e), (f), (g) or (h); X is C1-C4 alkylene; X1 is a direct link or C1-C6 alkylene; X2 is a direct link, CO, SO2, or NR5CO; and m is 0, 1 or 2; together with intermediates used in the preparation of compositions containing and the use as tachykinin angatonists of such derivatives.