baber/WOPTO huggingface dataset:
Patent EA-016397-B1 (EA)
Title: Genetic variants in the tcf7l2 gene as diagnostic markers for risk of type 2 diabetes mellitus
Inventor: GRANT STRUAN F A
IPC: A61P3/10
Filed: 2006-06-16
Abstract: Polymorphisms in the gene TCF7L2 are shown by association analysis to be a susceptibility gene for type II diabetes. Methods of diagnosis of susceptibility to diabetes, of decreased susceptibility to diabetes and protection against diabetes, are described, as are methods of treatment for type II diabetes.
Patent EA-017582-B1 (EA)
Title: Treatment of metastatic stage prostate cancer with degarelix
Inventor: PERSSON BO-ERIC
IPC: A61K38/08
Filed: 2009-02-10
Abstract: A method is provide for the treatment of metastatic stage prostate cancer in a subject and also a method for delaying or preventing the progression of localized or locally advanced prostate cancer in a subject comprising administration degarelix by the dosage comprising administration at an initial dose of degarelix with subsequent administration at a maintenance dose.
Patent EA-015712-B1 (EA)
Title: Inhibitors of akt (protein kinase b)
Inventor: JOSEPH SAJAN
IPC: A61K31/435
Filed: 2007-06-12
Abstract: The present invention relates to 4-[5-(2-Amino-ethanesulfonyl)-isoquinolin-7-yl]-phenol or a pharmaceutically acceptable salt thereof or a hydrate of the compound or the salt thereof as Akt inhibitors that are antineoplastic and/or antiviral agents as well as compositions comprising these compounds and methods of using these compounds.
Patent EA-014256-B1 (EA)
Title: Fuselage and method for reducing flying drag
Inventor: KRESHCHISHIN GENNADY TROFIMOVICH
IPC: B64C1/26
Filed: 2008-09-12
Abstract: The invention relates to aircraft engineering and can be used for improving aerodynamic quality of helicopters, aeroplanes, including traditionally designed airbuses and amphibian airplanes, ground-effect crafts and air-cushion vehicles, possibly by redesigning them. The aim of the invention is to reduce flying drag, possibly by redesigning an aircraft, a helicopter, a ground-effect craft and an air-cushion vehicle. The technical result is achieved by reducing a contacting area between the external surface of the fuselage tail section and a high-speed air flow. For this purpose, the above-mentioned contacting area is reduced by the increased area of orifices in the fuselage tail section; in order to increase the lifting force without increasing pressure resistance, the bottom of the aerodynamic channel is designed convex upwards, for example curved upwards along the shape of the convex side of the airfoil section. The top orifice in the skin of the aerodynamic channel can be located under the middle part of the fin and length wisely divided by said fin to the right and to the left, for example in two. The inventive redesign makes it possible to reduce the total drag of the fuselage and respectively reduce the required engine thrust.
Patent EA-018332-B1 (EA)
Title: Dynamic platform
Inventor: FEDCHENKO OLEG ANATOLIEVICH
IPC: G09B9/02
Filed: 2010-10-20
Abstract: The invention relates to increasing displacement in three degrees of freedom: longitudinal and transverse planes, vertical axis; and also to increasing power efficiency and design simplification. A dynamic platform comprises a movable beam mounted at the end of a support beam and provided with hinges and a drive mechanism connected to the support beam arranged on a cardan unit, the support beam has a rotary support, an elastic element and a drive mechanism connected to the cardan unit, the movable beam, the support beam and the cardan unit are mounted on a fabricated framework provided with a lifting mechanism and a drive mechanism connected to the cardan unit. A hydraulic drive or an electric motor can be used as a drive mechanism, wherein the elastic element can be a spring. The movable beam can be designed as a booth or a seat.
Patent EA-017064-B1 (EA)
Title: Crystal of benzimidazole compound
Inventor: HASHIMOTO HIDEO
IPC: A61K31/4439
Filed: 2009-03-09
Abstract: Provided is a crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole showing an X-ray powder diffraction pattern having characteristic peaks at interplanar spacings (d) of 10,06+0,2; 8,70±0,2; 6,57±0,2; 5,59±0,2 and 4,00±0,2 Angstroms. The present invention provides a stable antiulcer drug superior in the absorbability.
Patent EA-019586-B1 (EA)
Title: Method for measuring borehole oil output and device therefor
Inventor: ALIEV TELMAN ABBAS OGLY
IPC: E21B47/10
Filed: 2011-05-24
Abstract: The invention relates to oil production industry, in particular, to measuring engineering and can be used for measuring two-phase three component borehole oil output. The essence of the invention is characterized in that a method for measuring borehole oil output comprises measurement of electrical motor active power, pressure at discharge borehole line and calculation of formation liquid output. Additionally measured temperature, pressure and liquid level in a casing string a temperature at a discharge line and at the mouth of a borehole downhole and formation liquid and gas output are calculated by the claimed algorithm. The essence of the invention further comprises a device for automatic measurement of oil borehole output. The device comprises an electrical motor power transducer of a pumping unit, a pressure sensor and a temperature sensor at the borehole discharge line, a pressure sensor and a temperature sensor at the borehole discharge line, a pressure sensor and a temperature sensor at the mouth of a casing string and a liquid level sensor in the casing string. All sensors are connected via appropriate convertors to the control and indication block. The claimed invention provides to measure not only a borehole output but also a gas factor, to enhance validity of the measurement that allows to control and manage boreholes in an operative manner.
Patent EA-022176-B1 (EA)
Title: Building slab and method of production thereof
Inventor: YAMAGUCHI TAKAHIRO
IPC: E04F13/02
Filed: 2011-09-09
Abstract: According to the invention disclosed are a building slab that exhibits high weather resistance and has a film coating applied by ink-jet printing, which doesn't depend on dryness of a basic coating film, and a method for coating a building slab. The building slab comprises a basic film coating, inkjet film coating and a clear film coating which are sequentially formed on the surface of an inorganic slab. The inkjet film coating is a cured product of a UV-curable ink, and the clear film coating contains 0.1 to 10.0 wt.% of a light stabilizer and/or UV absorbent. The method of producing a building slab includes such steps as application of base coating onto the surface of an inorganic slab, application of inkjet coating by means of UV-curable ink onto the surface of the base-coated inorganic slab and curing the UV-curable ink through irradiation of UV rays, and making of clear coating by application of clear coating material containing 0.1 to 10.0 wt.% of a light stabilizer and/or UV absorbent, on solid basis, onto the surface of the inkjet-coated inorganic slab.
Patent EA-020812-B1 (EA)
Title: Personal wash compositions comprising specific blends of saturated to unsaturated triglyceride oils
Inventor: LIU HONGJIE
IPC: A61Q19/10
Filed: 2010-02-11
Abstract: The present invention provides personal wash compositions comprising 1 to 40% by wt. of a surfactant system and 1 to 40% by wt. of a blend of saturated and of unsaturated triglyceride oils where the amount of saturated triglyceride is 15 to 35 wt% of the blend and unsaturated is 85 to 65 wt% of the blend. The blend has an enthalpy of phase transition from 30 to 60 Joule/gram and an iodine value above 80. This specific formulation provides functional benefits and perfect balance between, on the one hand, spreadability and deposition and, on the other hand, retention of excellent foaming (at least 70% of the value of the same composition where the unsaturated triglyceride is used instead of the blend).
Patent EA-026099-B1 (EA)
Title: Mechanical wave gear drive
Inventor: MENSHIKOV GENNADY PETROVICH
IPC: F16H1/00
Filed: 2013-12-10
Abstract: The invention is related to the field of mechanics, in particular, to mechanical gears, and can be used for precise turning by a preset arbitrary angle and for continuous rotation about a horizontal or a vertical axis, which can be used for viewing a terrain by means of optical or radar devices in holography, in aviation, in spacecraft and space stations, particularly in cases where movements with especially high precision, high gear ratio are required as well as small weight and small size of the mechanism. The invention can be used also in electromechanical gyroscopes, in antenna system drives, especially in drives of phased antenna arrays. The technical objective of the invention is higher precision of the gear drive due to elimination of static backlash and reduction of resilient backlash, lower internal friction losses in the wave gear drive, i.e., higher efficiency of the gear drive, and, primarily, a drastic decrease in inherent bending stresses in the flexible shell of the flexible half-clutch. Said objective is attained by means of the following solutions: a mechanical wave gear drive comprising a rigid gear, a flexible gear, a wave generator, a gear clutch for coupling the flexible gear to the body, characterized in that the flexible gear and the wave generator are made completely floating, the wave generator is made of two parts between which cylindrical springs are positioned that provide backlash-free mesh in the wave gear drive; each part of the generator carries one pressing ball-bearing and two support ball-bearings that create the required shape of the flexible gear; the gear clutch consists of a flexible half-clutch with outside teeth that is an extension of the flexible gear of the wave gear drive, and a flexible half-clutch with inside teeth connected with the body of the gear drive.
Patent EA-032772-B1 (EA)
Title: Method for the preparation of an immunogenic composition for the treatment and/or prophylaxis of mycoplasma infections in a subject
Inventor: JORDAN DIANNA M MURPHY
IPC: C12N5/071
Filed: 2013-12-20
Abstract: The application describes a method for the preparation of an immunogenic composition for the treatment and/or prophylaxis of mycoplasma infections in a subject comprising the cultivation of mycoplasma bacteria in an eukaryotic cell system comprising a MDCK cell line or a Mc Coy cell line and up to 10% of serum, obtaining an antigen of the mycoplasma bacteria and addition of a pharmaceutically acceptable carrier. Said mycoplasma bacteria are selected from M. hyopneumoniae, M. hyorhinis and M. hyosynoviae.
Patent EA-028192-B1 (EA)
Title: Method of producing norbornene-substituted cyclopropane fullerene derivatives and polymers based thereon
Inventor: BIGLOVA YULIA NIKOLAEVNA
IPC: C08F32/08
Filed: 2015-10-23
Abstract: The invention relates to organic synthesis and specifically to a method of producing norbornene-substituted cyclopropane fullerene derivatives and synthesis of high-molecular compounds based thereon. Provided is a method of producing norbornene-substituted cyclopropane fullerene derivatives of general formula (9)by reacting the fullerene Cwith an ester of Formula 8taken in the molar ratio of fullerene C:ester=1:1, in the presence of a solvent and a base at temperature 20-25°C for 0.5-1.0 hours. A method of producing polymers of general formula (11)by polymerising norbornene-substituted cyclopropane fullerene derivatives of general formula (9) in the presence of a I-generation Grubb's catalyst taken in the molar ratio of Fullerene derivative:Grubb's catalyst I=35:1, in atmosphere of argon and in organic solvent medium at temperature 20-25°C for 12 hours, adding to the reaction mixture of ethyl vinyl ether for removal of catalyst residues, precipitation of polymer in methanol. The method enables to obtain norbornene-substituted cyclopropane fullerene derivatives, capable for metathesis polymerisation with formation of Fullerene containing polymers, followed by formation of thin films therefrom, serving as acceptor components in photovoltaic devices.
Patent EA-031141-B1 (EA)
Title: Method for fractionating an alcohol-containing liquid, and device for implementing the same
Inventor: VOJTENKOV NIKOLAY GRIGORIEVICH
IPC: C12F3/00
Filed: 2016-03-03
Abstract: The invention is related to fractionating distillation of alcohol-containing liquids in a centrifugal field and can be used to separate the ester-aldehyde fraction (EAF) together with intermediate mixtures. The source alcohol-containing liquid is divided in the device into two flows, one of which is set in rotary motion, and the second one is heated additionally to the alcohol-containing liquid boiling point and ejected through a random packing and a mesh to convert the liquid to a steam-gas-liquid emulsion; the emulsion is passed through a mesh in a centrifugal field to increase the inter-phase surface and to form ultrasonic waves; then it is fed to the rotating first flow of the alcohol-containing liquid, from which ester-aldehyde fraction and transient fractions in the form of floating bubbles with vapours of those fractions and gases dissolved in the alcohol-containing liquid are released. The device comprises a base 1 having a bubbler 2 with a thermometer 16 secured to it; a rotor drive 3; a top part of a stator 6 supported by legs (not shown); a steam separator 8 with a thermometer 17; an alcohol heater 9. A bubbler 2 is connected to the heater 9 and the steam separator 8 by a pipeline. Fastened to the top part of the bubbler 2 is a vapour extraction pipeline 22 connected to a released vapour condenser 10 provided with a condensate sensor 20 to which a condensate outlet pipeline 7 is connected. Also connected to the bubbler 2 is a transparent pipeline 12, one end of which is positioned opposite to the rotor 3, and the other above the top part of the stator 6. The rotor 3 consists of 2 disks connected to each other by vanes 4; at least one mesh 5 is placed on the inner parts of the vanes over the entire inside periphery of the rotor 1. The upper disk of the rotor 2 has an opening for passing the alcohol-containing liquid through a symmetrically disposed opening in the top part of the stator 6, a pipeline 13 connected to the bottom part of the tank of the steam separator 8 being secured to said symmetrically disposed opening. The group of inventions provides reduction of energy consumption.
Patent EA-030706-B1 (EA)
Title: Decked borehole explosive charge
Inventor: NIFADJEV VLADIMIR IVANOVICH
IPC: F42D1/08
Filed: 2016-01-28
Abstract: The invention is related to mining, in particular, to designs of decked borehole charges used in performance of blasting operations, primarily in open-cut mining of mineral deposits. The invention can be used also for blasting operations in construction. The technical objective of the invention is provision of a more efficient design with lower specific consumption of explosives, lower labour input, and automation of the decked borehole charge formation process. Said technical objective is attained by provision of a decked borehole charge consisting of explosive charges spaced over the borehole height and contacting a detonating cord connected to an initiating impulse source, air chambers and stemming, wherein explosive charges are hollow, for instance, spherical, and contact each other, the wall thickness of explosive charges and the number of such charges over the borehole height being determined in accordance with physical and mechanical properties of rocks surrounding the borehole. The explosive charges are freely movable in the borehole. The initiating impulse source is located near the top explosive charge in the borehole mouth. The initiating impulse source is located on the borehole bottom near the bottom explosive charge. The detonating cord may be arranged along the borehole wall.
Patent EA-030883-B1 (EA)
Title: Process for the production of light olefins and aromatics from a hydrocarbon feedstock
Inventor: WARD ANDREW MARK
IPC: C10G69/06
Filed: 2014-06-30
Abstract: The present invention relates to a process for the production of light olefins and aromatics from a hydrocarbon feedstock, comprising the steps of: (a) feeding a hydrocarbon feedstock into a FCC unit; (b) separating reaction products, which are generated from the FCC reaction, into a bottom stream, a middle stream and a top stream; (c) feeding the middle stream from the step (b) to a gasoline hydrocracker (GHC) unit; (d) separating reaction products of said GHC of the step (c) into an overhead gas stream comprising hydrogen, methane and C2-C4 paraffins, and a bottom stream comprising aromatic hydrocarbon compounds; (e) feeding the overhead stream from the gasoline hydrocracker (GHC) unit into a steam cracker unit.
Patent EA-037526-B1 (EA)
Title: Use of a pcsk9 inhibitor to treat hyperlipidemia
Inventor: BACCARA-DINET MARIE
IPC: A61P3/06
Filed: 2014-10-10
Abstract: The invention relates to methods for treating hyperlipidemia in patients who are not on statin therapy. The methods of the invention comprise administering to a patient a pharmaceutical composition comprising a PCSK9 inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody such as the exemplary antibody referred to herein as mAb316P.
Patent EA-029060-B1 (EA)
Title: Process for the preparation of vortioxetine salts
Inventor: LING ISTVAN
IPC: C07D295/08
Filed: 2015-01-30
Abstract: The invention relates to an improved process for the preparation of pharmaceutically active ingredients and also to high purity salts and pharmaceutical compositions prepared by said process. More particularly the invention relates to an economical process for the preparation of the compound having the international non-proprietary name (INN) vortioxetine and the chemical nomenclature 1-[2-(2,4-dimethyl-phenylsulfanyl)phenyl]piperazine. Vortioxetine corresponds to the following Formula:Still more particularly the invention relates to the preparation of high purity vortioxetine L-(+)-mandelate salt of the Formula IX, the conversion of this salt into other highly pure salts and also to the formulation of said salts.
Patent EA-038148-B1 (EA)
Title: Gas separation membranes based on fluorinated and perfluorinated polymers
Inventor: MERKEL TIMOTHY C
IPC: B01D71/32
Filed: 2016-04-28
Abstract: The invention relates to gas separation processes using membranes. The invention discloses a process for separating components of a gas mixture using gas-separation copolymer membranes comprising a selective layer made from copolymers of amorphous perfluorinated dioxolane and fluorovinyl monomers, wherein said monomer has a glass transition temperature Tg(c) that is at least 5°C, preferably 10°C, higher or lower than the glass transition temperature of a homopolymer, Tg(h) of the dioxolane monomer. The resulting membranes have superior selectivity performance for gas pairs of interest while maintaining fast gas permeance compared to membranes prepared using conventional perfluoropolymers, such as Teflon AF, Hyflon AD and Cytop.
Patent EA-037379-B1 (EA)
Title: Integrated hydrometallurgical and pyrometallurgical method for processing ore
Inventor: BOJCEVSKI DAVID
IPC: C22B3/04
Filed: 2017-09-19
Abstract: A process for recovering copper, uranium and one or more precious metals from an ore material, including: a. forming a heap of the ore material; b. subjecting the heap of the ore material to an acidic heap leach using an iron containing acidic leach solution in the presence of an oxygen containing gas, and producing a pregnant leach solution and a ripios; c. subjecting the ripios to flotation to produce a copper containing ripios concentrate and tailings; and d. subjecting the ripios concentrate to a smelting process to produce a smelted copper product; e. recovering copper and uranium from the pregnant leach solution.
Patent EA-039463-B1 (EA)
Title: Method and apparatus for decoding a video signal to extract source color volume information of an input bitstream from an sei message
Inventor: CHEN TAO
Filed: 2017-10-03
Abstract: Provided are a method and an apparatus for decoding a video signal to communicate source color volume information in a coded bitstream using SEI messaging. Such data include at least the minimum, maximum and average luminance values in the source data plus optional data that may include the color volume x and y chromaticity coordinates for the input color primaries (e.g., red, green and blue) of the source data, and the color x and y chromaticity coordinates for the color primaries corresponding to the minimum, average, and maximum luminance values in the source data. Messaging data signaling an active region in each picture may also be included.
Patent EA-036573-B1 (EA)
Title: Device for inserting a tongue
Inventor: FRANSSON JONAS
IPC: B27M3/18
Filed: 2017-12-20
Abstract: A handheld device 80 is disclosed for inserting a tongue 30 into an insertion groove 20 in a panel. The device includes a first part 10 including a power unit 16 which is configured for driving a puncher 14. The handheld device includes a second part 12, which is connected to the first part 10. The second part includes the displaceable puncher 14 and a guiding device 13 which is configured to guide the displaceable puncher 14 and the tongue 30. An outer edge 60 of the second part 12 includes a first positioning element 54 and a second positioning element 55. The first positioning element 54 and the second positioning element 55 are configured to be positioned at least partly in the insertion groove 20 during an insertion of the tongue into the insertion groove. The displaceable puncher 14 is configured to displace the tongue 30 from the handheld device to an inserted position in the insertion groove 20.
Patent EA-039378-B1 (EA)
Title: E-ticket and e-coupon, game system and game method based on an e-ticket and an e-coupon
Inventor: SILAEV ALEXANDER IVANOVICH
IPC: G07C15/00
Filed: 2020-01-12
Abstract: The invention relates to the entertainment industry, and more particularly to systems and methods for playing games based on searching for winning indexes in a game ticket with a specified prize. The present problem of providing and checking the correctness of a game process in a communication network for a remote user is solved in a game system and game method based on an electronic ticket and an electronic coupon (e-ticket and e-coupon). An e-ticket is displayed before the start of a game on the screen of a terminal or on a paper medium and contains a plurality of game indexes, an open code containing encrypted information about a combination of winning indexes which are stored on a game server, and information about prizes for a successful search. The user identifies the game indexes in the e-ticket and sends said indexes from the terminal to the game server. The game server compares the game indexes and the winning indexes, determines the result of the game, i.e. prize or no prize, and sends to the terminal an e-coupon for display or printing, which contains the game indexes and the winning indexes, the result of the game and an encryption key. The e-coupon allows the user to obtain their prize and/or to check on a public resource that the result of encrypting the combination of winning indexes using the aforesaid key matches the open code, and that any alteration of the key and/or the combination of winning indexes corrupts the open code.