baber/WOPTO huggingface dataset:
Patent BR-112023003948-A2 (BR)
Title: Compostos de antagonista de quinolina cgas
Inventor: JIAN QIU
IPC: A61P25/28
Filed: 2021-09-03
Abstract: COMPOSTOS DE ANTAGONISTA DE QUINOLINA CGAS. A presente invenção refere-se a compostos que são antagonistas de CGAS, métodos de preparação dos compostos, composições farmacêuticas que compreendem os compostos e seu uso em terapia médica.A presente invenção refere-se a compostos que são antagonistas de CGAS, métodos de preparação dos compostos, composições farmacêuticas que compreendem os compostos e seu uso em terapia médica.
Patent BR-112023019122-A2 (BR)
Title: Método de produção de um painel decorativo com estruturação melhorada
Inventor: HÜLLENKREMER FELIX
IPC: B32B21/04
Filed: 2022-04-14
Abstract: a presente invenção refere-se a um método para a produção de um painel decorativo, compreendendo as etapas seguintes de método: a) aplicar uma camada decorativa sobre um suporte; b) opcionalmente aplicar uma camada intermediária sobre a camada decorativa; c) aplicar uma camada de cobertura sobre a camada decorativa ou a camada intermediária e d) estruturar pelo menos uma camada (28) a ser estruturada, a dita camada (28) a ser estruturada sendo selecionada da camada decorativa, da camada intermediária e da camada de cobertura, caracterizado em que a etapa d) do método compreende as etapas do método a seguir: d1) gerar um feixe de laser (12); d2) dividir o feixe de laser (12) em uma matriz (16) de uma pluralidade de subfeixes; d3) guiar a matriz (16) de subfeixes para um modulador (24) para desativação seletiva dos subfeixes individuais; d4) guiar a matriz (16) de subfeixes do modulador (24) para um digitalizador óptico (26), a matriz (16) de subfeixes a jusante do modulador (24) compreendendo todos os subfeixes guiados para o modulador (24) ou um número reduzido de subfeixes e d5) guiar a matriz (16) de subfeixes do digitalizador (26) sobre a camada (28) a ser estruturada; d6) a camada (28) a ser estruturada sendo estruturada negativamente sob a ação dos subfeixes a fim de gerar uma estrutura tridimensional (34).
Patent BR-112023019401-A2 (BR)
Title: Proteínas multivalentes e métodos de triagem
Inventor: ARNE HAGEN AUGUST SCHEU
IPC: A61K38/00
Filed: 2022-03-24
Abstract: proteínas multivalentes e métodos de triagem. são providos no presente documento arcabouços de proteínas multivalentes úteis como terapêuticos e úteis na identificação de novos compostos terapêuticos. a invenção também se refere a construtos polipeptídicos de múltiplos domínios com múltiplos domínios de ligação e um domínio estrutural. também são providos no presente documento métodos de uso dos arcabouços de proteínas multivalentes providos para identificar novas terapêuticas candidatas e novas terapêuticas deste modo identificadas.
Patent BR-122016016837-A2 (BR)
Title: moléculas de ligação a cd3; anticorpos de ligação a cd3; composições farmacêuticas; e usos da molécula de ligação a cd3
Inventor: Leslie s johnson
IPC: C07K16/00
Filed: 2012-05-16
Abstract: a presente invenção refere-se a moléculas de ligação a cd3 capazes de se ligarem a cd3 humano e não humano, e, em particular, a tais moléculas que possuem reatividade cruzada com cd3 de um mamífero não humano (por exemplo, um macaco cinomolgo). a invenção também refere-se a usos de tais anticorpos e fragmentos de ligação a antígeno no tratamento de câncer, doenças autoimunes e/ou inflamatórias e outras condições.
Patent CZ-2495-A3 (CZ)
Title: Smoke cartridge for camouflaging ground objects
Inventor: HALFAR VACLAV ING
IPC: F41H9/08
Filed: 1995-01-05
Abstract: This smoke pot for camouflaging ground objects contains a pyrotechnic cartridge  based on  a rotating paraboloid of plasticised red phosphorus (7), burning after initiation in the area of burning, for a minimum of 3 minutes. It consists of cylindrical metal sheet (1) with a bottom and a cap (2) equipped with a pit for the initiator (3) and the outlet holes (4) for the exhaust of burnt gases and a pyrotechnic body (5) of the pyrotechnic element. Between the cap (2) of the smoke pot and the pyrotechnic body (5) there is a homogenizing area (8) for homogenizing the burnt products of the pyrotechnic mixtures.<IMAGE>
Patent CZ-12899-A3 (CZ)
Title: LED signal lamp
Inventor: CEJNEK MILAN ING CSC
IPC: F21V13/04
Filed: 1999-01-15
Abstract: In the present invention, there is disclosed a LED signal lamp consisting of a LED light source, a reflector and a cover glass wherein refractive catadioptric prisms (2), reflective elements (4) and dispersive elements (6) are used for adjusting emission of light from the LED source (1) wherein said reflective elements (4) are located on a surface (3) of defined form and said dispersive elements (6) are disposed on the cover glass (5). Said system of the reflective elements (4) lies on the defined form surface (3) being restricted for example by mounting dimensions. The system of reflective surfaces of the individual reflective elements (4) is selected so that the impinging parallel light beam is adjusted after reflection on these reflective elements (4) of the system to be parallel with the lamp optical axis, or dispersed with parameters meeting required distribution of light of the given type of the signal lamp. The system of dispersive elements (6) located on the cover glass (5) as well as the dispersive elements located on the surfaces of the individual reflective elements (4) serve for dispersion of the light beam, wherein the cover glass (5) is free of optical elements or is provided with a decorative optics, only.
Patent CZ-27899-A3 (CZ)
Inventor: SIKL FRANTISEK ING
IPC: B60R25/06
Filed: 1999-01-27
Abstract: Mechanické zařízení tvoří základna (1) mechanismu s násuvným dílem (7) pro pedály (17). K základně (1) je připojen z jedné strany zámek (2) a z druhé strany vodič (4), v němž jsou uložena táhla (3), která jsou na spodních koncích spojena spojovacím dílem (6) a na horních koncích závorou (5). V uzamčené poloze jsou pedály (17) zajištěny v násuvném díle (7) závorou (5) a táhla (3) jsou rozepřena vůči podlaze (15) vozidla. Zámek (2) táhel je opatřen vybráními (16) pro odpružené aretovad kuličky (14), které vymezují polohu táhel (3). V horní části základny (1) mechanismus je na straně vodiče (4) vytvořena zábrana (8), opatřena vybráními, ve kterých jsou vedena táhla (3).
Patent CZ-31697-A3 (CZ)
Title: Biscyclopentadienyl-diene complexes, process of their preparation, compositions containing such complexes being suitable as olefin polymerization catalysts and olefin polymerization process
Inventor: TIMMERS FRANCIS J
IPC: C08F38/00
Filed: 1995-07-14
Abstract: Biscyclopentadienyl, Group 4 transition metal complexes are formed by contacting a biscyclopentadienyl Group 4 metal halide, hydrocarbyl, hydrocarbyloxy or amide complex with a conjugated diene. Uniquely, the ansa-rac diastereomer is selectively isolated and may be reconverted to the halide form if desired. When combined with standard activating cocatalysts or activated with an activating technique, the complexes form catalysts for polymerizing olefins, diolefins and/or acetylenically unsaturated monomers.
Patent SK-18794-A3 (SK)
Title: Yoke suspension of leaf spring for bogies of rail vehicles
Inventor: WENKE SIEGBERT
IPC: F16F1/26
Filed: 1994-02-16
Abstract: The invention relates to a chain-link suspension for the running gear of rail vehicles having high balance quality which is suitable for high travel speeds and high axial travel masses. The spring bolts (3) and/or chain links (1) have different diameters in their support areas. As far as possible the dimensions of the UIC replacement parts are adopted for the upper support area of the chain link (1), the upper chain-link block (4) and the upper spring bolt (3). The diameter of the lower support area including chain-link block (5) and/or the diameter of the lower spring bolt (3) are increased to such an extent that the transverse and longitudinal damping values required for high travel speed and large axial travel masses are achieved. The support area of the chain-link block (4, 5) is provided with a depression or the support area of the spring bolt (3) is provided with a flattened portion, the said depression or flattened portion contributing to increasing the longitudinal damping. In order to increase the transverse spring constant of the wheel set guidance, the chain links (1) can be arranged spread out apart from one another in the transverse direction of the wagon. The chain-link suspension according to the invention is provided for the running gear of rail vehicles and is particularly suitable for retrofitting in UIC standard wagons. <IMAGE>
Patent SK-38294-A3 (SK)
Title: Piperidine-triazine compounds acting as stabilizers of organic materials, mixtures containing them and their using for stabilization of organic materials
Inventor: BORZATTA VALERIO
IPC: C07D493/10
Filed: 1994-03-31
Abstract: Novel piperidine-triazine compounds of the formulae (Ia) and (Ib) suitable for use as light, heat and oxidation stabilisers for organic materials. The meanings of R1, R2, R3, G1, G2, L1, L2, m and n are defined in the text. <IMAGE>
Patent SK-44493-A3 (SK)
Title: Device for excavation of openings by flame with combined control
Inventor: SEKULA FELIX
IPC: E21B7/14
Filed: 1993-05-06
Abstract: A device for cutting of holes in the thick walls, with the use of the flame, is created based on the oval body which consists of the front wider part (1) wit he the head (7), of the middle streamlined part (4) and swivelling front calibrating part (3) with the tack (13) to the fuel medium supply (14). The head (7) of the wider part (1) is equipped with the fuel medium jet pairs (2.1, 2.2, 8.1, 8.2, 9.1, 9.2, 10.1, 10.2, 11.1, 11.2) placed in the shouldering (7.1, 7.2, 7.3, 7.4 and 7.5). In the hollow space (7) of the equipment, there is located the touch part (15) together with the information system, the executive system (16) of the control closed to the jet pairs (8.1, 8.2, 9.1, 9.2, 10.1, 10,2, 11.1, 11.2) for fuel medium and control system (2.3) of the front pair of jets (2.1, 2.2). The middle streamlined part (4) continues to the swivelling calibration part (3) having an upper and bottom positioned elastic tack (3.1.1, 3.1.2). The carrying part is the skeleton (19) enabling the equipment to be decomposed to two (three) parts independent of each other. The energy supply for this equipment is provided based on the fuel medium inlet (14).
Patent SK-88897-A3 (SK)
Title: Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
Inventor: ABERG A K GUNNAR
IPC: A61P27/02
Filed: 1995-12-11
Abstract: A composition comprising DCL, or a pharmaceutically acceptable salt thereof, for treating allergic rhinitis, allergic asthma, retinopathy or other small vessel diseases associated with diabetes mellitus, urticaria, or symptomatic dermographism in a human, while avoiding the concomitant liability of adverse side effects associated with the administration of non-sedating antihistamines, by administering to said human a therapeutically effective amount of DCL or pharmaceutically acceptable salt thereof.
Patent AT-513788-A3 (AT)
Title: Lichtschacht mit Dichtung
Inventor: STADLER JÖRG
IPC: E04F17/06
Filed: 2014-01-09
Abstract: Ein Lichtschacht, insbesondere Fertiglichtschacht, zur Montage an eine Gebäudeöffnung, weist eine zur Anlage an das Gebäude bestimmte offene Seite sowie eine nach oben hin geöffnete Seite auf. An den zur Anlage an das Gebäude bestimmten Seiten ist eine Dichtung (3) angeordnet. Die Dichtung (3) weist eine integrierte Seele (4) auf.
Patent CH-627330G-A3 (CH)
Title: Waterproof watchcase of non-circular shape
IPC: G04B37/08
Filed: 1976-01-30
Abstract: The watchcase includes a bezel (1) inside the aperture of which is fitted a heeled glass (2) which presses the seal (3) onto the top of the side walls of the case body (4). Around the perimeter of the bezel, the side walls situated towards 6 o'clock and 12 o'clock are removed so as to enable the ends of the clips (12) fitted into the longitudinal grooves (11) of the case body (4) to be made accessible. The ends of these clips are fitted into the grooves (10) formed at the ends of the remaining side walls of the bezel. <IMAGE>
Patent CH-618561G-A3 (CH)
Title: Method for transporting away textured yarns
IPC: D02G1/20
Filed: 1978-03-02
Abstract: Textured yarns are transported away at texturing speeds of more than 1500 m/min. from a texturing apparatus via a rotating screen drum or a perforated roller, through which air is sucked. The yarn roving obtained during texturing is drawn off via a drawing-off unit at a speed which is 3 to 40 times, preferably 6 to 30 times, the speed at which the yarn roving passes from the texturing apparatus on to the rotating screen drum or perforated roller. At the same time, breaking devices between the screen drum and the drawing-off unit, in conjunction with the breaking effect of the yarn drawn off in a grazing manner via the screen drum, compensate linear yarn-density fluctuations in a self-regulating way.
Patent CZ-289192-A3 (CZ)
Title: Process for preparing an article from emulsified fat
Inventor: BROCKHUS JEROEN JOHANNES J J
IPC: A23D7/00
Filed: 1992-09-21
Abstract: The invention relates to a cream, to a churned product made therefrom, and to a processes for producing such a cream and such a product. Experience has shown that it is difficult to prepare products which simultaneously exhibit a stability, texture and ease of manufacture similar to that of butter, without sacrificing the nutritional qualities of margarine by the incorporation of saturated fats, particularly butterfat. We have now determined that the use of interesterified fat avoids the difficulties of post hardening. The invention provides a process for the production of a spread which comprises the steps of:   a) preparing a vegetable fat cream comprising at least one interesterified fat having an solid fat index at 10 DEG C of greater than 30% and preferably less than 50%, b) dosing into the said vegetable fat cream 1-25% on total fat phase of vegetable oil, preferably around 15%, of an oil with a higher iodine value than the interesterified fat, c) churning the cream/fat mixture to obtain a water in oil emulsion spread having a solid fat index at 10 DEG C of greater than 20% and preferably less than 50%.   Preferably, the fat blend of the cream comprises 40-60 wt.% of a liquid oil and 60-40 wt.% of an interesterified blend of one or more fats rich in palmitic and/or lauric fatty acids together with one or more fats rich in eighteen carbon fatty acid residues. Preferably the surface-weighted mean diameter (D3,2) of the dispersed droplets in the cream should be prior to churning in the range 3-8  mu m, preferably 3-6  mu m, most preferably 4-5  mu m.
Patent CZ-317591-A3 (CZ)
Inventor: HUSTAK JAROMIR ING
IPC: H01J37/24
Filed: 1991-10-21
Abstract: Zapojení tvoří zatmívací clona (3) spojená přes pikoampérmetr
(4), vstupní zesilovač (5), diferenciální zesilovač
(6) s prvním vstupem výstupního zesilovače (8), jehož
druhý vstup je spojen přes předzesilovač (10) s detektorem
(11) a jeho výstup přes integrátor (9) s výstupní svorkou
(16) linearizační smyčky.
Patent CZ-341791-A3 (CZ)
Inventor: BRABEC EMIL ING
IPC: F16K15/04
Filed: 1991-11-12
Abstract: Sestává z vícedDného tělesa (21, 22), v němž jsou vytvořeny
centrický kanál pro průchod mazací tekutiny s dávkovacím
prostorem (D) sedlo (Z) zpětného veDtDu a uzavíracího
ventilu (U) a spodní doraz (K) a zároveň uloženy dávkovači
element (23) s radiální vůlí (M), uzavírací prvek (24), pružiny
(25, 26) a kolíček (27). Průchod tekutiny je ve směru
Šipky (P). Podstata spočívá v tom, že sedlo (Z) zpětného
ventilu i uzavíracího ventilu (U) jsou uspořádána tak, aby
mohla být uzavírána shodným uzavíracím prvkem (24).
Patent CZ-360992-A3 (CZ)
Title: Plasma pulsating nozzle
Inventor: KUBES PAVEL DOC RNDR CSC
IPC: H05H1/34
Filed: 1992-12-09
Abstract: The pulsating nozzle is formed by an anode (1), opposite which, in the direction of accelerating movement of the plasma, there is a cathode (2) in which there is a through-hole (3) oriented in the direction of accelerating movement of the plasma.<IMAGE>
Patent CS-381591-A3 (CS)
Title: Serotonin antagonists
Inventor: DIXON ARNOLD KEITH DR
IPC: A61P25/18
Filed: 1991-12-16
Abstract: 3,7-disubstituted indole derivatives of formula I <CHEM> wherein R1, R2, n, X, Y and Z are as defined in the description, are useful for the treatment of psychiatric disorders.
Patent CS-8706567-A3 (CS)
Title: Process for producing self-supporting ceramic bodies having required surface properties
Inventor: NEWKIRK MARC S
IPC: C04B41/88
Filed: 1987-09-10
Abstract: The invention comprises a method of making self-supporting composite ceramic structures by the oxidation reaction of a body of molten parent metal precursor with a vapor-phase oxidant to form an oxidation reaction product. This reaction or growth is continued to form a thick, self-supporting ceramic body. The composite is recovered and in a separate subsequent operation, the surface is coated with one or more materials in order to effect desired changes in the properties of the surface, e.g., hardness, corrosion resistance.
Patent CZ-100097-A3 (CZ)
Title: Process for preparing a mixture of aminomethyl cyclohexanes and diaminomethyl cyclohexanes
Inventor: DARSOW GERHARD DR
IPC: B01J23/889
Filed: 1997-04-02
Abstract: A process for the continuous production of a mixture of amino- and diamino-methylcyclohexanes of formula (I) and (II) respectively, comprises catalytic hydrogenation of diaminotoluenes (III) at 150-260 degrees C with hydrogen at 20-500 bar. The process uses an unsupported catalyst consisting of reduced tablets made by compressing a mixture of powdered oxides or hydroxides of cobalt, manganese, copper and alkaline earth metals which may also contain one or more oxides or hydroxides of Group V and/or VI transition metals.
Patent CZ-104097-A3 (CZ)
Title: Washing and cleaning agent
Inventor: KOTTWITZ BEATRIX
IPC: C11D3/08
Filed: 1995-09-27
Abstract: The object of the invention is to prepare washing or cleaning agents, especially washing agents with apparent densities of over 500 g/l, which contain water-soluble silicate builders superimposed on the crystalline layered disilicates in these compositions. This is achieved by agents containing anionic and non-ionic tenside, inorganic builders and possibly organic co-builders, in which the inorganic builder in these agents is a spray-dried and then compressed and ground silicate in quantities of over 10 wt.% and organic co-builders in quantities of 0 to under 20 wt.%.
Patent CZ-133098-A3 (CZ)
Title: Olefin polymer preparation, film or foil and process for producing thereof
Inventor: BECKER RONALD F
IPC: C08K5/5353
Filed: 1998-04-29
Abstract: A polymer composition and fiber, film or sheet prepared therefrom, which contains (i) an olefin polymer containing an acid neutralizing agent other than a metallic salt of a saturated or unsaturated fatty acid, and ii) a stabilizer system distributed throughout the polymer, the stabilizer system including (a) a phosphite selected from 2,2',2''-nitriloÄtriethyl-tris(3,3',5,5'-tetra-tert.butyl-1,1-biphenyl -2,2'-diyl)phosphiteÜ and tris(2,4-di-tert-butylphenyl) phosphite; and (b) a N,N-dialkylhydroxylamine. Also disclosed is a method for preparing a polyolefin fiber, film or sheet, which includes adding the above stabilizer to an olefin polymer containing an acid neutralizing agent other than a metallic salt of a saturated or unsaturated fatty acid, thereby producing a stabilized olefin polymer; and extruding the stabilized olefin polymer through a die.
Patent CZ-151696-A3 (CZ)
Title: Bmp receptor encoding dna sequence
Inventor: COOK JONATHAN SHAUN
IPC: A61K38/00
Filed: 1994-11-23
Abstract: The present invention relates to an isolated BMP receptor kinase protein or soluble fragment thereof, a DNA sequence coding for said BMP receptor kinase protein or said soluble fragment thereof, a recombinant expression vector comprising said DNA sequence, a host cell comprising said recombinant expression vector, a method of expressing said BMP receptor kinase protein or soluble fragment thereof, a method for identifying compounds capable of binding to said BMP receptor kinase protein or soluble fragment thereof, a method for determining the amount of such compounds in a sample, and antibodies to said BMP receptor kinase protein.
Patent CZ-161495-A3 (CZ)
Title: Contact and intraocular lenses with absorbers of ultraviolet radiation and process for producing thereof
Inventor: LABSKY JIRI ING CSC
IPC: G02B1/04
Filed: 1995-06-20
Abstract: The invention concerns contact and intraocular lenses formed by a polymer from 89 to 99.6 % of vinyl monomers, 0.2 to 6 wt.% of polymerizable absorbers of ultraviolet radiation, 0.1 to 3 wt.% of a crosslinker and 0.1 to 2 wt.% of a polymerization initiator. As vinyl monomers, the monomers are used selected from the group comprising alkyl acrylates and methacrylates, hydroxyalkyl acrylates and methacrylates, fluoroalkyl acrylates and methacrylates, (alkyloxy)alkyl acrylates and methacrylates, (acyloxy)alkyl acrylates and methacrylates, (acylamino)alkyl acrylates and methacrylates, (alkylsulfinyl)alkyl acrylates and methacrylates, (alkylsulfonyl)alkyl acrylates and methacrylates, tris(alkyloxy)silylalkyl acrylates and methacrylates, N-vinylpyrrolidone, N-vinylpiperidone and their combinations. As polymerizable absorbers of ultraviolet radiation, substances selected from the group of substances comprising substances of general formula (I) or (II) are used where R<1>, R<2> are hydrogen, acryloyloxy, methacryloyloxy, (acryloyloxy)alkyloxy, (methacryloyloxy)alkyloxy, 3-(methacryloyloxy)-2-hydroxypropyloxy, vinyl, allyloxy, (acryloylamino)methyl, (methacryloylamino)methyl groups, R<3>, R<4> are hydrogen, hydroxy, halogen, cyano, alkyloxy, alkyl, (alkyloxy)alkyl, hydroxyalkyl groups, the alkyls being alkyl groups with 1 to 4 carbon atoms or (III) or (IV), where R is acryloyl or methacryloyl group, or their mixture. As cross-linking agents, substances are used selected from the group comprising acrylic and methacrylic esters of dihydric alcolhols, amino alcohols, amines, allyl acrylates and methacrylates and diallyl esters of dicarboxylic acids and as polymerization initiators, common azo and peroxy initiators and initiators cleavable by UV radiation.
Patent CZ-171996-A3 (CZ)
Title: Method of joining an elastic material with a base and article produced in such a manner
Inventor: WIDLUND URBAN
IPC: A61F5/44
Filed: 1994-12-21
Abstract: Elastic tapes consisting of non-weldable elastic warp threads (7) and weldable thermoplastic weft threads (6), can be easily fixed to one side of a cover layer (3) of a disposable diaper, for example, by ultrasonic welding of the thermoplastic weft threads (6).
Patent CZ-176595-A3 (CZ)
Title: The application of anticonvulsive agents for the preparation of medicaments intended for treating parkinson's disease and parkinson's syndromes
Inventor: BOIREAU ALAIN
IPC: A61K31/428
Filed: 1994-01-03
Abstract: PCT No. PCT/FR94/00003 Sec. 371 Date Jun. 6, 1995 Sec. 102(e) Date Jun. 6, 1995 PCT Filed Jan. 3, 1994 PCT Pub. No. WO94/15601 PCT Pub. Date Jul. 21, 1994This invention relates to an application of riluzole or the pharmaceutically acceptable salts in the preparation of drugs for the treatment of Parkinson's disease and parkinsonian syndromes.