baber/WOPTO huggingface dataset:
Patent CA-2373433-C (CA)
Title: Spiroimidazolidine derivatives, their preparation, their use and pharmaceutical preparations comprising them
Inventor: WEHNER VOLKMAR
IPC: A61K31/4184
Filed: 2000-05-06
Granted: 2010-12-14
Abstract: The present invention relates to spiroimidazolidine derivatives of formula (I) in which E, V, W, X, R1 and R2 have the meanings indicated in the claims. The compounds of formula (I) are valuable pharmaceutical active compounds which are suitable, for example, for the therapy and prophylaxis of inflammatory disorders, for example of rheumatoid arthritis, or of allergic disorders. The compounds of formula (I) are inhibitors of the adhesion and migration of leukocytes and/or antagonists of the adhesion receptor VLA-4 belonging to the integrins group. They are generally suitable for the therapy and prophylaxis of illnesses which are caused by an undesired extent of leukocyte adhesion and/or leukocyte migration or are associated therewith or in which cell-cell or cell-matrix interactions which are based on interactions of VLA-4 receptors with their ligands play a part. The invention furthermore relates to processes for the preparation of the compounds of formula (I), their use and pharmaceutical preparations which contain compounds of formula (I).
Patent CA-2373591-C (CA)
Inventor: LOCH MICHAEL
IPC: C23C4/137
Filed: 2002-02-27
Granted: 2013-10-22
Abstract: The invention provides a process for applying a heat shield- ing coating system on a metallic substrate. The coating system comprises at least three individual layers selected from the group of barrier layer, hot gas corrosion protection layer, protection layer, heat barrier layer, and smoothing layer. The coating system is applied to the metallic substrate by low pressure plasma spray- ing in a single operation cycle. This process enables the layers to be applied in an arbitrary sequence. The process is preferably used in applying a coating system to a turbine blade, particularly a stator or a rotor blade of a stationary gas turbine or of an aircraft engine, or to another component in a stationary or air- craft turbine that is subjected to hot gas.
Patent CA-2376144-C (CA)
Inventor: JOHNSON DWIGHT N
IPC: E03D1/30
Filed: 1998-11-18
Granted: 2005-11-15
Abstract: A fill valve has a main valve with a valving surface contacted by a valve disk. A series of offset radial paths separated by a toroidal path permit free radial flow at full open and quiet tortuous flow as the valve closes. Removal of a cap permits access to the main valve for cleaning. Indicia in the valve body provide easy height adjustments. A riser base is made up of easily molded locking parts and provides a variable height adjustment structure that is shielded from view. A flexible cup performs multiple functions including serving as a pilot valve, a vacuum breaker valve and a seal. A float for operating the pilot valve is pivotally mounted without extra parts or fasteners.
Patent CA-2377606-C (CA)
Inventor: KEMPE RON
IPC: C23C26/00
Filed: 2000-06-22
Granted: 2009-09-08
Abstract: La présente invention concerne une roue d'avancement (24) destinée à une machine à travailler le bois, qui se trouve en contact d'entraînement avec une pièce de bois de façon qu'elle entraîne la pièce de bois précitée le long d'un élément de travail du bois.  De préférence, la roue d'avancement peut être entraînée dans une seule direction et elle peut tourner librement dans la direction opposée à la direction d'avancement. La roue d'avancement est de préférence composée d'une partie moyeu (40) et d'une partie jante (38) qui peut être séparée de la partie moyeu (40). La partie jante comprend des dents agencées de façon qu'elles s'étendent selon un angle d'hélice par rapport à l'axe de la roue, dents qui sont de préférence munies d'une couche de diamant résistante à l'usure afin de pouvoir coopérer avec la pièce de bois.
Patent CA-2378533-C (CA)
Inventor: HILGER BERND
IPC: A61K38/22
Filed: 2000-06-28
Granted: 2006-02-14
Abstract: L'invention concerne des conjugués d'érythropoïétine comprenant une érythropoïétine, laquelle comprend à son tour au moins un groupe aminé libre et possédant la propriété biologique <i>in vivo</i> de provoquer l'augmentation de la production des réticulocytes et des globules rouges par la moelle osseuse. L'érythropoïétine selon l'invention est choisie dans le groupe constitué de l'érythropoïétine humaine et de ses analogues qui ont la conformation primaire de l'érythropoïétine humaine modifiée par l'ajout de 1 à 6 sites de glycosylation ou par le réarrangement d'au moins un site de glycosylation. L'érythropoïétine selon l'invention est liée par covalence à un à trois groupes poly(éthylène glycol) alcoxy inférieur, chaque groupe poly(éthylène glycol) étant lié par covalence à ladite érythropoïétine via un lieur représenté par la formule -C(O)-X-S-Y-, le C(O) du lieur formant une liaison amide avec un desdits groupes aminés, où X et Y sont définis dans le descriptif et les revendications. La masse moléculaire moyenne de chaque fraction de poly(éthylène glycol) est comprise entre environ 20 kilodaltons et environ 40 kilodaltons tandis que la masse moléculaire du conjugué est comprise entre environ 51 kilodaltons et environ 175 kilodaltons.
Patent CA-2380994-C (CA)
Inventor: SOLIMAN SAMIR S
IPC: G01S1/00
Filed: 2000-08-30
Granted: 2010-03-09
Abstract: A method and apparatus for conducting a pilot signal search in a wireless communications network. The location of a mobile is determined within the network. This location is then used in determining search window sizes and other search parameter information that is used to search all pilot signals identified in a designated pilot signal set. Search window size is also determined based upon the location of the mobile and another component related to multipath effects for a transmitted pilot signal.
Patent CA-2381411-C (CA)
Inventor: PEARSON GREGORY
IPC: C01F7/02
Filed: 2000-08-11
Granted: 2008-12-30
Abstract: The present invention pertains to a micro-crystalline beohmite containing additive in a homogeneously dispersed state. Suitable additives are compounds containing elements selected from the group of alkaline earth metals, alkaline metals, rare earth metals, transition metals, actinides, silicon, gallium, boron, titanium, and phosphorus. Said MCBs according to the invention may be prepared in several ways. In general, a micro-crystalline boehmite precursor and an additive are converted to a micro-crystalline boehmite containing the additive in a homogeneously dispersed state. Also claimed are shaped particles and catalyst compositions comprising the as-prepared micro-crystalline boehmite.
Patent CA-2387588-C (CA)
Inventor: GLADIN ALAIN
IPC: A23G9/08
Filed: 2000-10-12
Granted: 2006-02-21
Abstract: The invention relates to a method for producing an iced food product (3), wherein two compositions (2,4) adapted to form said product are introduced into a mould (36), at least one of the compositions being an external composition which is adapted to form an outer surface (7) of said product. The two compositions (2,4) are introduced into the mould at the same time. The flow of the /each external composition (2), the temperature of the/each external composition (2) prior to introduction and the temperature of the mould (36) prior to introduction are such that each fraction of the/each external composition (2) freezes as soon as it is received by the mould.
Patent CA-2388391-C (CA)
Inventor: DALLAS L MURRAY
IPC: E21B33/068
Filed: 2002-05-31
Granted: 2004-11-23
Abstract: A reciprocating lubricator includes a lubricator base, a lubricator tube connected at the top to a lubricator head and inserted through a packing in the lubricator base to provide a sealable chamber adapted to accommodate a downhole tool to be inserted into a wellbore against well fluid pressure. The chamber in the lubricator tube is sealed using equipment mounted to the lubricator head. Injectors interconnecting the lubricator base and the lubricator head reciprocate the lubricator tube through the lubricator base. When a downhole tool is inserted into the wellbore, the lubricator head rests against the lubricator base to provide a low, safe and stable position for operation of the equipment mounted to the top of the lubricator head.
Patent CA-2388988-C (CA)
Title: Transmission a changement de vitesses continu
Inventor: MILLER DONALD C
IPC: F16H15/28
Filed: 2000-10-24
Granted: 2009-06-02
Abstract: L'invention concerne une transmission à changement de vitesses continu prévue pour être utilisée dans des machines et des véhicules à commande rotative ou linéaire. La transmission à un seul axe offre un procédé de changement de vitesses manuel simple pour l'utilisateur. L'invention traite également d'un autre mode de réalisation qui change automatiquement de vitesse en fonction de la vitesse de rotation de la roue. En outre, la commercialisation de transmissions à galets de traction nécessite d'améliorer la fiabilité, la facilité de changement de vitesses, la fonction et la simplicité de la transmission. La transmission selon l'invention peut être utilisée dans des véhicules, comme des automobiles, des motocyclettes et des bicyclettes. La transmission peut, par exemple, être entraînée par un mécanisme de transfert de puissance comme une roue dentée, un engrenage, une poulie ou un levier, entraînant éventuellement un embrayage unidirectionnel fixé à une extrémité de l'arbre principal.
Patent CA-2391863-C (CA)
Title: Eyeglass accessory frame, eyeglass device, and method of forming a magnetic eyeglass appliance
Inventor: SMITH GREG S
IPC: G02C9/00
Filed: 2001-08-09
Granted: 2007-04-10
Abstract: An eyeglass accessory frame includes an auxiliary frame (102). The auxiliary frame includes a heat-treated magnetic alloy. The heat-treated magnetic alloy of the auxiliary frame is configured to magnetically couple the auxiliary frame (102) to a primary frame (104) having magnetizable material. A method is also provided.
Patent CA-2392273-C (CA)
Inventor: KERR KENDALL WILLIAM
IPC: H01L23/12
Filed: 2000-11-22
Granted: 2007-05-01
Abstract: An active package for an integrated circuit may include an integrated circuit and an active component that is part of the circuit topology for the integrated circuit. The active component forms at least a portion of the housing for the integrated circuit. The integrated circuit may be housed in a shell formed by one or more discrete components. The active package may be formed in the same geometry and dimensions as a standard passive integrated circuit package, or may be formed in a shape to fit inside a standard or specially made battery package, or for another special application. A smart component may include a discrete component or a semiconductor-based resistor, capacitor or inductor, and a separate integrated circuit housed in the same housing as the discrete component or a semiconductor-based resistor, capacitor or inductor. The integrated circuit may control at least one electrical parameter of the discrete component or a semiconductor-based resistor, capacitor or inductor. In one embodiment, the integrated circuit may maintain the resistance, resistivity, capacitance, inductance, etc. of the component inside a narrow range in order to create a high-precision component regardless of changes in environmental changes such as temperature, pressure, humidity, etc.
Patent CA-2399538-C (CA)
Title: Ballistic vest
Inventor: BLAAUW MARC
IPC: F41H5/04
Filed: 2001-02-05
Granted: 2008-04-22
Abstract: The invention relates to a ballistic vest containing a stack of flexible fabrics and a stack of flexible unidirectional layers, in which the fabrics contain strong fibres of a first kind, the unidirectional layers contain strong fibres of a second kind, and in which the fibres in a unidirectional layer run essentially parallel and a re disposed at an angle to fibres in an adjacent layer which is greater than 0 degrees, where in that the flexible fabric is a loose fabric and is located on the strike side of the vest. The percentages by weight of the loose fabrics and the stack of UD layers preferably is between 15:85 and 30:70 %. In that case, a vest of area] density less than 6 kg/m2 can have such ballistic resistance as to stop an Action 3 bullet with a velocity of up to 437 m/s with a trauma to NIJ Standard of less than 44 mm.
Patent CA-2400315-C (CA)
Inventor: WILLIAMS PETER
IPC: A01D43/14
Filed: 2002-09-11
Granted: 2003-10-14
Abstract: -11- A chamber is formed in the upper end of a brush saw cutting head housing. The brush saw cutting element drive spindle's upper end projects into the chamber. The drive spindle's lower end projects beneath the housing and is drivingly couplable to the cutting element. A disc is mounted against the underside of the cutting element. A cavity is formed in the disc. At least one channel extends through the disc, between the cavity and the disc's external rim. An aperture extends through the drive spindle, between the chamber and the cavity. Herbi- cide supplied to the chamber flows from the chamber, through the drive spindle aperture, into the cavity. The drive spindle rotates the disc. Centrifugal force imposed on herbicide within the cavity forces the herbicide through the channel(s) onto the underside of the cutting element, for transfer onto the stumps of material cut by the element.
Patent CA-2406088-C (CA)
Title: Nouveaux derives de phenyle-propargylether
Inventor: ZELLER MARTIN
IPC: C07D333/00
Filed: 2001-05-15
Granted: 2009-06-30
Abstract: L'invention concerne des dérivés de phényle-propargyléther représentés par la formule générale (I), notamment les isomères optiques de ceux-ci ainsi que les mélanges de ces isomères. Selon cette formule (I), R1 représente hydrogène, alkyle, cycloalkyle ou aryle éventuellement substitué, R2 et R3 représentent chacun indépendamment hydrogène ou alkyle, R4 représente alkyle, alcényle ou alkynyle, R5 R6, R7, et R8 représentent chacun indépendamment hydrogène ou alkyle, R9 représente hydrogène, alkyle éventuellement substitué, alcényle éventuellement substitué ou alkynyle éventuellement substitué, R10 représente aryle éventuellement substitué ou hétéroaryle éventuellement substitué, et Z représente halogène, aryloxy éventuellement substitué, alkoxy éventuellement substitué, alcényloxy éventuellement substitué, alkynyloxy éventuellement substitué, arylthio éventuellement substitué, alkylthio éventuellement substitué, alcénylthio éventuellement substitué, alkynylthio éventuellement substitué, alkylsulfinyle éventuellement substitué, alcénylsulfinyle éventuellement substitué, alkynylsulfinyle éventuellement substitué, alkylsulfonyle éventuellement substitué, alcénylsuflonyle éventuellement substitué ou alkynylsulfonyle éventuellement substitué. Ces composés possèdent des propriétés de protection des plantes utiles et peuvent être utilisés avantageusement en agriculture pour combattre ou prévenir l'infestation de plantes par des micro-organismes phytopathogènes, plus spécialement des champignons.
Patent CA-2410506-C (CA)
Title: Method and apparatus for summing asynchronous signal samples
Inventor: GALLAGHER SEAN
IPC: H04N7/173
Filed: 2001-06-04
Granted: 2008-10-21
Abstract: A method and apparatus for digitizing multiple data streams having different clocks spreads an error due to clock drift is spread across many clock cycles in extremely small amounts. To combine two data streams, the method interpolates one or more samples between existing samples of one of the two data streams and then adjusts a number of samples of said one of the two data streams to maintain balance in a downstream synchronizing buffer. This occurs prior to combining the two data streams. The adjusting may be performed by adding or decimating samples from the interpolated samples. To combine two asynchronous data streams having clocks offset in frequency, first, a first data stream is clocked into and out of a first buffer using a first clock associated with the first data stream. Second, a second data stream is clocked into a second buffer using a second clock associated with the second data stream and clocking the second data stream out of the second buffer using the first clock. Third, samples are interpolated into and decimated from samples of the second data stream prior to clocking the second data stream into the second buffer based on an overflow or underflow of the second buffer. Finally, the outputs of the first and second buffers are combined.
Patent CA-2413083-C (CA)
Inventor: HAYDAY WILLIAM A
IPC: C11D3/20
Filed: 2001-06-06
Granted: 2013-09-10
Abstract: A method for dry-cleaning garments which comprises treating the garments with a mixture of dipropylene glycol tertiary-butyl ether (DPTB) and water for a period of time sufficient to effect dry-cleaning, wherein the weight ratio of DPTB to water is at least 9:1.
Patent CA-2419877-C (CA)
Title: Storage stable tretinoin and 4-hydroxy anisole containing topical composition
Inventor: PARAB PRAKASH V
IPC: A61K47/14
Filed: 2001-08-03
Granted: 2009-11-24
Abstract: A long-term storage stable tretinoin and 4-hydroxyanisole composition contains low molecular weight polyethylene glycol, antioxidant, a chelating agent, lower alkanol and water. The chelating agent provides at least two of the functions of oxygen scavaging, free radical chain terminating and reducing.  The composition has a pH of 2.5 to 5 and a water content of at least 12%.
Patent CA-2424905-C (CA)
Title: Street graphic cage
Inventor: FENTRESS DONALD
IPC: G09F23/00
Filed: 2003-04-04
Granted: 2010-06-22
Abstract: A street graphic cage for a post top light wherein the cage is installed around a globe positioned on said post. The street graphic cage has an upper frame element defining a plurality of panel apertures. The panel apertures receive translucent panels therein such that they may be backlit and illuminated. The panels are readily removable without entry into the globe or electrical system of the post top light and may contain user defined indicia thereon. The upper frame element may also have a plurality of logo block apertures which can receive either translucent logo blocks or decorative die-cast aluminum blocks. The cage may also have a lower circular frame element for affixing the cage to the post top light below the globe.
Patent CA-2432539-C (CA)
Title: Method for preparing latex
Inventor: MASSILLON HENRI
IPC: C08F2/38
Filed: 2001-12-20
Granted: 2010-05-25
Abstract: The invention concerns a method for preparing latex by batch free radical polymerisation of one or several monomers, which consists in polymerising: (a) one or several fine dispersions of one or several finely dispersed monomers and (b) one or several latex seeds or one or several seeding polymers.
Patent CA-2441983-C (CA)
Inventor: LINDEKENS LUC
IPC: B01L3/00
Filed: 2002-03-20
Granted: 2011-08-02
Abstract: There is disclosed process for preparing a substrate 1. Process for preparing a substrate having thereon sites reactive with the reactive groups of a molecular probe, the process comprising the steps of applying to the substrate surface a material comprising one or more reactive sites having an activated ethylenically unsaturated double bond of the formula I: Wherein, if n= 0, m=  1, X3 is carbon and X1 is nitrogen, the bond between them being triple, and X4 does not exist; if n= 1, m= 1, X3 is carbon and X1 is oxygen or sulphur, the bond between them being double, and X2 is oxygen or sulphur or nitrogen substituted by an organo substituent; if n= 1, m= 1 or 2, X3 is sulphur and X1 is oxygen, the bond between them being double, and X2 is nitrogen substituted by an organo substituent; R1, R2, each independently represent hydrogen, hydroxyl or organo group, R3 and R4 each independently represent hydrogen or organo group, eventually containing a silicon atom R1 and R2 being not linked to R4. and, in a further step, of covalently binding the reactive group of the molecular probe to the activated ethylenically unsaturated double bond of the reactive sites having formula I. Preferred activated unsaturated moiet(ies) comprises unsaturated ester moiet(ies) such as (meth)acrylate moiet(ies).  Preferred probes comprise amino groups thereon. Preferred strong links are covalent bonds. Preferred linking reactions are Michael addition reactions.  The substrate having probes deposed thereon may be used to interact with a target. Other aspects of the invention relate to substrates and multi-reactive systems (such as microarrays) so prepared; uses thereof; and products and information obtained therefrom.
Patent CA-2451230-C (CA)
Inventor: EDER CLAUDIA
IPC: C12P17/08
Filed: 2002-06-20
Granted: 2011-03-15
Abstract: The invention relates to novel compounds of general formula (I), wherein R(1), R(2), R(3), R(4) independently represent hydrogen or an alkyl radical. The compounds of formula (I) are inhibitors of KDR-kinase, having an anti-angiogenetic effect, and are suited for the prevention and/or treatment of malignant illnesses. The compounds of formula (I) can be obtained by fermenting the microorganism Eurotium echinalutum Delacroix (DSM 13872) or by means of chemical derivatization of the compounds obtained after fermenting said microorganism. The invention also relates to a method for producing compounds of Formula (I), the use of said compounds for producing a drug for treating malignant illnesses and illnesses which can be treated by inhibiting KDR-Kinase, and for pharmaceutical preparations containing at least one compound of formula (I).
Patent CA-2456507-C (CA)
Title: Hyperbranched amylopectin for use in methods for surgical or therapeutic treatment of mammals or in diagnostic methods, especially for use as a plasma volume expander
Inventor: SOMMERMEYER KLAUS
IPC: A61K31/718
Filed: 2002-08-06
Granted: 2011-05-03
Abstract: The invention relates to the use of hyperbranched amylopectin which has an average branch degree of between > 10 and 25 mol % and a molecular weight (Mw) ranging from 40.000 - 800.000 Dalton and the derivatives thereof in methods for surgical or therapeutic treatment of human or animal bodies or in a diagnostic method, preferably as a plasma volume expander. Plasma volume expanders based on hydroxy-ethylated amylopectin have, as a result of hydroxy ethylation, hitherto exhibited the disadvantage of incomplete metabolism and thus temporary tissue storage which is linked to side-effects. According to the invention, novel plasma expanders based on polysaccharides which do not exhibit the same disadvantages as the former are provided. Improved, completely metabolised plasma expanders based on hyperbranched amylopectin which can be obtained therefrom so that native plant-amylopectins are altered by transglycosylation in such a way the adjustable, high degree of branching enables control of the serum-.alpha.-amylase decomposition so that no or only a very insignificant degree of hydroxy ethylation is necessary.
Patent CA-2463987-C (CA)
Title: Compositions and methods for increasing compliance with therapies using aldehyde dehydrogenase inhibitors and treating alcoholism
Inventor: LEDERMAN SETH
IPC: A61K45/06
Filed: 2002-11-04
Granted: 2011-03-08
Abstract: Compositions and methods for treating, preventing, or reducing alcoholism, in particular methods for increasing patient compliance with therapies that require the intake of an ALDH inhibitor comprising the step of administering a monoamine oxidase B inhibitor.