baber/WOPTO huggingface dataset:
Patent EP-0534492-B1 (EP)
Inventor: WARSHAWSKY ALAN M
IPC: C07D498/04
Filed: 1992-09-28
Granted: 1996-12-18
Abstract: The present invention relates to compounds of the formula <CHEM>  wherein   B<5> and B<6>   are each independently hydrogen; hydroxy; -OR<6> wherein R<6> is a C<5>-C<8> alkyl or an Ar-Y group wherein Ar is aryl and Y is a hydrogen or C<5>-C<8> alkyl; or, where B<5> and B<6> are attached to adjacent carbon atoms, B<5> and B<6> can be taken together with said adjacent carbons to form a benzene ring or methylenedioxy; A   is a bond, methylene or oxygen, sulfur or NR<8> or NCOR psi wherein R<8> is hydrogen, a C<5>-C<8> alkyl or an Ar-Y- group and R psi  is -CF<7>, a C<5>-C<5><4> alkyl or an Ar-Y- group; R<7>   is hydrogen or -CH<6>OC(O)C(CH<7>)<7>; R<5>   is hydrogen, C<5>-C<8> alkyl or -CH<6>OC(O)-C(CH<7>)<7>; and n   is an integer 1 to 3, which are useful as inhibitors of enkephalinase and ACE.
Patent EP-0509576-B1 (EP)
Inventor: WATNEY JOHN P
IPC: H04N7/30
Filed: 1992-04-01
Granted: 1998-01-28
Abstract: The invention provides techniques for changing the quantization used in multiple generations of data quantization such that the errors incurred in subsequent generations are substantially the same as the error incurred in the first generations even though the complexity of the data has been changed. In a preferred embodiment, quantizing factors are selected from a preselected finite non-degenerative set of quantizing factors provided in the form of arrays of a periodic series of individual quantizer values, wherein a special numerical relationship is maintained between corresponding quantizer values in successive arrays. A different quantizing factor may be selected for each generation of compression/decompression as required by changing data complexity as when performing a layering process during the generations. In another embodiment, an over-quantizing factor is chosen large enough to compress the data to a greater extent than that required in the first generation, such that sufficient compression still is provided in subsequent generations even though the same quantizing factor is used while the complexity of the data is being changed. If for some reason the complexity of the data changes faster than expected, it is necessary to change the quantizing factor to fit the data into the allotted space. To moderate the associated increase in noise, the invention technique incudes a dither rounding process wherein a psuedo random number sequence in the range of 0...1.0 is selectively added as determined by a threshold. The invention also includes estimating a quantizing factor applied in a previous generation of image recording if this information is not available explicitly, by distinguishing the peaks and/or valleys of histogram. The amplitudes of the peaks and/or valleys represent the number of counts of the respective values of frequency coefficients to be quantized. <IMAGE>
Patent EP-0526950-B1 (EP)
Inventor: DE RIJK ROBERT
IPC: B65B7/28
Filed: 1992-08-06
Granted: 1994-11-02
Abstract: The invention relates to a method for closing a packing (4) consisting of two parts (2,3) by folding an edge (16) of the one packing part (3) in a continuous movement round a flange (15) of the other packing part (2) and pressing together the flange (15) and the edge (16). The invention further relates to an apparatus (1) for performing this method having a folding edge (14) divided into segments (9), wherein the segments (9) are movable in radial direction parallel to a pressure surface (8) of the closing apparatus (1) to a first closing position in which the flange (15) and the edge (16) are folded together and are movable therefrom transversely of the pressure surface (8) to a second closing position in which the flange (15) and the edge (16) are pressed together. <IMAGE>
Patent EP-0508687-B1 (EP)
Inventor: INGALL ANTHONY HOWARD
IPC: C07F9/38
Filed: 1992-04-02
Granted: 1995-09-13
Abstract: There are disclosed compounds of formula I, <CHEM>     wherein Q represents CR<1>R<2>,     R represents O or CR<3>R<4>,     W represents O or CH2, R<1>, R<2>, R<3> and R<4> independently represent hydrogen or halogen, X represents S(O)nR<5>, alkyl C1-6, alkoxy C1-6, acylamino C1-6, CONR<6>R<7>, NR<8>R<9>, halogen, a 5- or 6-membered S containing heterocycle, or phenyl optionally substituted by alkyl C1-6,     n represents 0, 1 or 2, R<5> represents aryl or alkyl C1-6 optionally substituted by one or more substituents selected from hydroxy, alkoxy C1-6, halogen and aryl; R<6>, R2<7>, R<8> and R<9> independently represent hydrogen or alkyl C1-6,     Y represents NH2 or alkoxy C1-6, and     Z represents an acidic moiety, in addition, when R represents CR<3>R<4>, then -Q-Z may also represent hydroxy or -OP(O)(OH)2, and pharmaceutically acceptable salts thereof, with certain provisos, for use as pharmaceuticals.
Patent EP-0533559-B1 (EP)
Inventor: CANO JOEL
IPC: E02F3/47
Filed: 1992-09-16
Granted: 1995-08-23
Abstract: The invention relates to a pincer grab excavator making it possible to dig trenches in the immediate vicinity of pre-existing obstacles, of the type in which the grab is provided at its upper part with a square rod which engages in a guiding component of corresponding shape suspended from the upper part of a lifting machine, while being able to pivot about a vertical axis, winders intended to receive the hydraulic hoses for controlling the grab being fitted to the guiding component. The winders (7) are offset laterally towards the lifting machine (1) and the upper part (6) of the guiding component (4) is supported by the lifting machine (1) at a point which is offset with respect to the vertical axis of the guiding component (4), so as to compensate for the tilting moment resulting from the offset of the winders and to keep the axis of the guiding component in a substantially vertical position. <IMAGE>
Patent EP-0556314-B1 (EP)
Title: Procede et appareil servant a fournir des instructions telechargees destinees a etre executees par un regisseur de peripherique
Inventor: RAASCH CHARLES F
IPC: G06F13/12
Filed: 1991-11-08
Granted: 1998-08-26
Abstract: Un procédé et un appareil servant à télécharger des instructions et d'autres informations vers un régisseur de périphérique (103) utilisé dans un ordinateur (102) compatible ISA (Industry Standard Architecture), utilisent un système permettant de télécharger des instructions à partir de l'ordinateur compatible ISA (102) vers une mémoire vive (109) accessible au régisseur de périphérique (103). Le régisseur de périphérique (103) exécute ensuite ces instructions afin d'émuler les fonctions de circuits intégrés des séries INTEL 8042 et 8742 classiques. Le régisseur de périphérique (103) présente aussi d'autres fonctions non comprises dans les 8042 ou 8742 classiques lorsqu'il exécute d'autres instructions téléchargées se trouvant dans la mémoire vive.
Patent EP-0580667-B1 (EP)
Inventor: EVANS CHRISTOPHER THOMAS
IPC: C07C69/013
Filed: 1992-04-21
Granted: 2000-09-20
Abstract: PCT No. PCT/GB92/00730 Sec. 371 Date Feb. 13, 1995 Sec. 102(e) Date Feb. 13, 1995 PCT Filed Apr. 21, 1992 PCT Pub. No. WO92/18444 PCT Pub. Date Oct. 29, 1992   <IMAGE>  (Ia)   <IMAGE>  (Ib)   <IMAGE>  (IIa)   <IMAGE>  (IIb)  The individual enantiomers of the compounds (Ia), (Ib), (IIa) or (IIb), optionally substituted by non-interfering substituent(s). The novel enantiomers can be obtained by biotransformation. The (Ia) or (IIa) compounds can be used for the synthesis of chiral carbocyclic nucleosides.
Patent EP-0667898-B1 (EP)
Inventor: INGRAM VERNON M
IPC: A61P25/28
Filed: 1992-07-10
Granted: 2001-10-10
Abstract: Novel TAU/neurofilament protein kinases, PK40 and PK36, are essentially purified and characterised. Novel immunoassays relating to the kinases and inhibitors for the kinases also are provided. Finally, DNA sequences encoding the kinases and cell lines relating to the kinases are provided. <IMAGE>
Patent EP-0596928-B1 (EP)
Inventor: ZACCA NADIM M
IPC: A61B17/00
Filed: 1992-07-15
Granted: 2000-04-05
Abstract: A device for treating obstructions in vessels or small openings in the body, comprising a rotatable ablator tip which is guided to the obstruction in a reduced diameter configuration, expanded and rotated to remove the obstruction, and contracted to remove the device from the body. The variably expandable abrasive tip coil in one embodiment is actuated by piston means within the coil. A pair of collars is attached to the ends of the coil, and the piston effects relative longitudinal axial movement of the collars and the respective ends of the coil tip. When the ends of the coil tip are so moved, expansion and contraction of the diameter of the coil tip results. In another embodiment, the expansion tip coil is actuated by an expandable and contractible bellows disposed within the coil. In another embodiment, the expansion and contraction of the coil tip are affected by longitudinal axial movement of an internal coil attached to one end of the coil tip, within an outer coil attached to its other end. In another embodiment, expansion and contraction of the coil tip are effected by an inflatable balloon disposed within the coil tip. The balloon expansion means enlarges preferably at the central portion of the coil to make a bulge. In alternative embodiments, there is provided a combined atherectomy and balloon angioplasty device employing either a fixed or variable diameter rotatable abrasive burr, and an angioplasty balloon disposed proximal to the burr.
Patent EP-0561125-B1 (EP)
Inventor: NAEGELE CORNEL
IPC: A47D13/08
Filed: 1993-01-28
Granted: 1996-10-09
Abstract: A device for securing and controlling a child, having a chest harness (1) or the like, and having a chord (4) or the like which is attached to both narrow sides of the chest harness and via which a person guiding the child can regulate the distance of the child and his direction of movement, a single chord (4) being provided which is continuous with the person guiding the child and is attached removably to the chest harness (1) by both its ends. <IMAGE>
Patent EP-0584497-B1 (EP)
Inventor: MAASS BURKHARD
IPC: B65H1/14
Filed: 1993-07-03
Granted: 1996-09-25
Abstract: Safety device in the feeder of a paper-sheet processing machine with a stack-lifting chain (3), controlled so as to be freely rotating, for raising and lowering the feed stack (2), with drive means for carrying along the stack-lifting chain (3) for raising the feed stack (2), with drive means for carrying along the stack-lifting chain (3) for lowering the feed stack (2) and with means for disconnecting the drive connection between the drive means and stack-lifting chain (3) for lowering the feed stack (2) in the event that the force acting on the stack-lifting chain from the feed stack (2) exceeds a limiting value. <IMAGE>
Patent EP-0583960-B1 (EP)
Inventor: TAO EDDIE VI-PING
IPC: C07D317/50
Filed: 1993-08-13
Granted: 1997-05-21
Abstract: This invention provides a novel process for the synthesis of bicyclic aromatic sulfonic acids employing reacting a bicyclic aromatic compound with sulfur trioxide-N,N-dimethylformamide complex in the presence of a water miscible, non-reactive solvent. The resulting sulfonic acid may be converted into the corresponding sulfonyl halide by the reaction with a thionyl halide. This invention further provides a novel process for the synthesis of bicyclic aromatic sulfonamides employing the reaction conditions described supra followed by an ammonolysis or amination. The resulting bicyclic aromatic sulfonamides can then be reacted with an appropriately substituted isocyanate to synthesize diaryl sulfonylureas.
Patent EP-0594291-B1 (EP)
Inventor: SHIBANO MITSUGI
IPC: A61P33/10
Filed: 1993-09-01
Granted: 2002-12-18
Abstract: An intermediate useful in the synthesis of milbemycin derivatives having an ether bond at the 13-position and which is represented by the general formula (IIId) : <CHEM> wherein R represents a methyl group, an ethyl group, an isopropyl group or a sec-butyl group, and R<5> and R<6'> each individually represents a hydrogen atom or a protecting group, and related precursors as well as to a process for producing these intermediates.
Patent EP-0588559-B1 (EP)
Inventor: VIRDI RANVIR SINGH
IPC: C08K5/36
Filed: 1993-09-09
Granted: 1999-05-06
Abstract: A metal dialkyldithiocarbamate or other such compound including a group of the formula R2NCS- or R2NS- is useful as a rubber accelerator/vulcanising agent, wherein each R is C5-18 branched alkyl.
Patent EP-0631493-B1 (EP)
Inventor: DALL DESMOND M
IPC: H04W88/02
Filed: 1993-03-19
Granted: 1998-02-04
Abstract: A cerclage fixation component (436) and a screw fixation component (440) are engageable together to form a composite bone fixation device. The cerclage component (436) may be a ladder plate with openings defined between bridges (442). The openings provide sockets for bosses (462) of the screw fixation component.
Patent EP-0598111-B1 (EP)
Inventor: SIMONELLI JAMES M
IPC: H02M7/48
Filed: 1993-06-09
Granted: 1997-03-12
Abstract: Un circuit onduleur configurable de manière à assurer tant une tension de sortie de courant alternatif à 120 volts qu'une tension de sortie de courant alternatif à 240 volts avec les mêmes composants et des connexions par cavaliers faciles à réaliser est configuré comme deux demi-ponts en parallèle pour une tension de courant alternatif à 120 volts à comme un seul pont entier pour le fonctionnement sous une tension de courant alternatif à 240 volts.
Patent EP-0653121-B1 (EP)
Inventor: TRAVIS CHRISTOPHER JULIAN
IPC: H03H17/00
Filed: 1993-07-29
Granted: 1997-01-22
Abstract: Un synchroniseur audio numérique comprend une mémoire tampon ou une paire de mémoires tampon (12, 16) en série avec un filtre d'interpolation numérique (14). Un circuit de commande (18) détecte s'il y a un 'glissement' entre l'entrée et la sortie, nécessitant la perte ou l'ajout d'un échantillon, et le filtre exécute un cycle de réglage du temps de propagation en fonction de cela. Le filtre (14) prend la forme d'un filtre passe-tout à réponse impulsionnelle infinie de forme récurrente en utilisant la rétroaction (Figures 4, 5, 6 ou 7) qui donne subjectivement un bon résultat même s'il introduit un temps de temporisation de groupe dépendant de la fréquence, est également facile à mettre en application, et a un faible temps de temporisation total.
Patent EP-0720754-B1 (EP)
Inventor: CRAMPTON STEPHEN JAMES
IPC: G02F1/025
Filed: 1993-09-21
Granted: 1997-11-19
Abstract: Le dispositif comprend une couche de silicium (3) séparée d'un substrat (1) par une couche de matière isolante (2). Une nervure (4) ayant une surface supérieure (4A) et deux surfaces latérales (4B, 4C) est formée dans la couche de silicium (3) afin d'obtenir un guide d'ondes pour la transmission de signaux optiques. Une jonction dopée latérale (7, 9, 8) est formée entre les surfaces latérales (4B, 4C) de la nervure (4) de sorte qu'il est possible d'appliquer un signal électrique sur la jonction (7, 9, 8) afin de réguler la densité des porteurs de charge sur une partie substantielle de la section transversale de la nervure (4) et modifier l'indice de réfraction effectif du guide d'ondes.
Patent EP-0624362-B1 (EP)
Inventor: TENNIGKEIT JUERGEN
IPC: D06P3/08
Filed: 1994-02-12
Granted: 1996-03-06
Abstract: A multistage method for the dyeing of human hair which, in particular, improves the covering power and is mild on the hair and, furthermore, permits the production of numerous shades of colour using a small number of dye compositions, consists of the following steps:   a) application of an alkaline oxidation dye mixture which contains at least one developer and at least one coupler substance as well as an oxidising agent, predominantly to the portion of the human hair which is adjacent to the scalp, the mixture being adjusted to the shade required for the complete dyeing;   b) rinsing and shampooing the hair after the dye has acted; c) application of an acidic oxidation dye mixture which contains at least one developer and at least one coupler substance as well as an oxidising agent to all the hair, and d) rinsing the hair after the dye has acted.
Patent EP-0619998-B1 (EP)
Inventor: BECKER MICHAEL
IPC: B29C65/04
Filed: 1994-03-03
Granted: 2002-08-28
Abstract: A container capable of containing components of a mixture in chambers separated by a peelable seal constructed from a multi-layer film. The multi-layer film has at least one layer of a RF-responsive material and an interior layer of non-RF responsive material. When the layers are subjected to RF energy, the RF-responsive layer heats the interior layers resulting in a bond in the form of a peelable seal between the interior layers. The peelable seal is capable of withstanding external pressures to the container, such as from dropping the container. The seal may be selectively opened to allow mixture of components contained therein. <IMAGE>
Patent EP-0624376-B1 (EP)
Inventor: ZLOTNICK GARY W
IPC: C12P21/00
Filed: 1994-05-02
Granted: 2000-03-15
Abstract: Described herein is a method for removing toxic lipooligosaccharide (LOS) from outer membranes of Gram-negative cocci, such as Neisseria meningitidis. LOS-depleted outer membranes and LOS-depleted soluble outer membrane proteins can be prepared, which are able to elicit bactericidal antibodies against homologous strains of bacteria. Vaccines and other uses of the preparations are further described.
Patent EP-0656334-B1 (EP)
Inventor: SCARLETT JOHN
IPC: B01J23/889
Filed: 1994-01-06
Granted: 1998-04-22
Abstract: The prodn. is of cyclohexanedimethanol (I) of trans:cis isomer ratio greater than about 1:1 by the hydrogenation of a dialkylcyclohexanedicarboxylate (II) (where alkyl is 1-4C) of trans:cis isomer ratio less than about 1:1. The process comprises: (a) providing a hydrogenation zone contg. a granular heterogenous ester hydrogenation catalyst (HC) which contains Cu or a Gp. VIII metal; (b) supplying to the zone a vaporous feed stream contg. H2 and a hydrogenatable material comprising (II) at an inlet temp. above the dew point of the mixt.; (c) maintaining the zone at 150-350[deg]C and 150-2000 psia (about 10.34-137.9 bar); (d) passing the feed stream through the zone; and (e) recovering from the zone the desired (I) with the specified trans:cis isomer ratio.
Patent EP-0642452-B1 (EP)
Inventor: MUELLER BRUCE M
IPC: B65D47/20
Filed: 1993-12-10
Granted: 1998-04-22
Abstract: A dispensing closure is provided with a body (24, 324, 524) having an outlet passage (40, 340, 540). A sleeve (80, 380, 580) is mounted on the body for rotation relative to the body. The sleeve has a transverse deck (102, 402, 602) defining a discharge passage (120, 420, 620) for communicating with the body outlet passage as the discharge passage moves in an arc relative to the body. In one embodiment, a seal (419, 437) is provided between the sleeve deck and the body around the outlet passage and discharge passage. In a preferred embodiment, an actuator (160, 460, 660) is mounted on the sleeve for rotation with the sleeve. Engaging structures (51, 52, 204, 208; 351, 352, 504, 508; 551, 552, 704, 708) are defined by the body and the actuator for tilting the actuator between a closed position and an open position while the actuator is rotated with the sleeve. The actuator includes engaging portions (204, 208; 504, 508; 704, 708) for engagement with drive members (51, 52; 351, 352; 551, 552) projecting upwardly from the body through openings (110, 112; 410, 412; 610, 612) in the sleeve. Engagement between the drive members and actuator is effected on opposite sides of the pivot axis of the actuator so as to effect tilting of the actuator between an open position and a closed position.
Patent EP-0685072-B1 (EP)
Inventor: CARR ANTHONY HUGH
IPC: G01N35/02
Filed: 1994-02-09
Granted: 1999-03-03
Abstract: Un appareil de surveillance comprend un dispositif de support (1008) conçu pour recevoir plusieurs éléments (602) à surveiller dans un réseau, chaque élément possédant une référence d'identification unique (616) lisible par machine associée avec lui, et la disposition étant telle que les éléments sont déplaçables dans différentes positions dans le réseau; un dispositif de détection (1024) est conçu pour surveiller de manière intermittente et répétée chaque élément dans le réseau pour surveiller les changements dans une variable associée avec chaque élément et pour lire la référence associée avec chaque élément; un dispositif pour fournir à un ordinateur (1004) des données sur la variable surveillée et sur la référence lisible par machine de chaque élément. Le dispositif d'ordinateur relie la variable surveillée à la référence de chaque élément, indépendamment de la position de l'élément dans le réseau.
Patent EP-0686113-B1 (EP)
Inventor: RICKELS STEPHEN TERENCE
IPC: B62M11/16
Filed: 1994-02-28
Granted: 1997-06-04
Abstract: Moyeu de bicyclette à engrenages épicycloïdaux comprenant des pignons planétaires primaires et secondaires (12 et 13) positionnés côte à côte sur l'axe du moyeu. Un sélecteur fendu (11) comprenant une première et une deuxième pièce (15 et 16) est monté sur une tige de support (17) et se déplace axialement par rapport au moyeu. Des butées (19 et 21) situées respectivement sur les pièces (15 et 16) peuvent être forcées sélectivement dans des cannelures (31 et 32) formées à l'intérieur des pignons (12 et 13) de façon à bloquer le pignon sélecté avec l'axe (14) en mode de transmission de l'entraînement. Le sélecteur (11) peut être déplacé axialement en butée contre un manchon afin de régler sa position axiale contre l'action d'un ressort de rappel autorisant ainsi les changements entre les grandes et petites vitesses et permettant ainsi de réaliser un montage compact.
Patent EP-0684785-B1 (EP)
Inventor: AKERSON STEVE HEART
IPC: G01F23/296
Filed: 1994-01-24
Granted: 2000-12-06
Abstract: A method and apparatus for monitoring and indicating whether a tracheal tube is located in the trachea or esophagus during an endotracheal intubation of a human or animal is disclosed. In a calibration mode, the resonant frequency of the tube is determined by generating a signal at a plurality of frequencies and finding the signal which propagates with the greatest amplitude. This :indicates the resonant frequency. When the tube is inserted into the patient, the resonant frequency of the system shifts, thus the amplitude of the signal changes. Based on known characteristics of the trachea and esophagus, the amount of change is dictated by whether the tube has been inserted into the trachea or esophagus. Alternatively, the device can continually determine the resonant frequency and use this to monitor the level of liquid in a tank.
Patent EP-0698213-B1 (EP)
Inventor: HAWKE DAVID HARRY
IPC: G01N33/53
Filed: 1994-05-20
Granted: 1997-10-08
Abstract: L'invention concerne un complexe immobilisé d'un ou plusieurs glucides marqués.
Patent EP-0713461-B1 (EP)
Inventor: VOLZ PETER
IPC: B60T8/36
Filed: 1994-08-05
Granted: 1998-11-11
Abstract: On décrit un régulateur de pression qui présente, en particulier dans la section de boîtier affaiblie par des trous voisins (1, 2), une sollicitation mécanique aussi faible que possible. C'est pourquoi, à une distance définie proche de la paroi (Y) par rapport à la plus faible épaisseur de boîtier (A1) entre les deux trous adjacents (1, 2), on prévoit au moins un évidement (3) dans la surface du boîtier (5).
Patent EP-0673937-B1 (EP)
Inventor: YOSHINO HIROSHI
IPC: C07D405/12
Filed: 1994-09-08
Granted: 2003-11-26
Abstract: Novel bicyclic heterocyclic sulfonamide and sulfonic ester derivatives represented by general formula (I) having an antitumor activity and a reduced toxicity, pharmacologically acceptable salts thereof, and a process for producing the same; wherein ring A represents an optionally substituted mono- or bicyclic aromatic group; ring B represents an optionally substituted 6-membered unsaturated hydrocarbon ring or 6-membered unsaturated heterocyclic group containing one nitrogen atom; ring C represents an optionally substituted 5-membered heterocyclic group containing one or two nitrogen atoms; W represents a single bond or -CH=CH-; X represents -NR<1>- or oxygen; Y represents carbon or nitrogen; Z represents -NR<2>- or nitrogen; and R<1> and R<2> represent each independently hydrogen or lower alkyl. <CHEM>