baber/WOPTO huggingface dataset:
Patent PT-1197507-E (PT)
Inventor: GERTZMANN ROLF DR
IPC: C08G18/38
Filed: 2001-09-27
Abstract: A composition comprises mono- and poly-asparaginic acid or their addition products. A Composition comprises mono- and poly-asparaginic acid esters of formula (I) or their addition products comprising a compound of formula (II) and a thiol compound of formula (III). X-(NH-CH(CH2COOR<2>)-COOR<1>)m (I) R<1>OOC-CH=CH-COOR<2> (II) (HS)nR<3> (III) X-(NH2)m (IV) X = group obtained by removal of the primary amino group(s) from (cyclo)aliphatic or (aryl)aliphatic, where the bound mono- or poly-amine containing the primary amino group has mol. wt. of 60-6000 and contains NCO reactive groups and/or functional groups inert at 100 degrees C; R<1> and R<2> = 1-18C (preferably 1-8C) alkyl; R<3> = group containing heteroatom with further NCO reactive or inert groups; n = 1-4; and m = at least 1. Independent claims are also included for: (1) The preparation of these esters by reacting mono- or poly-amines of formula (IV) with compounds of formula (II) and thiol compound(s) of formula (III); and (2) Two-component polyurethane systems containing this composition.
Patent PT-1296740-E (PT)
Title: Delivery of a substance into the dermis
Inventor: HARVEY NOEL G
IPC: A61K38/28
Filed: 2001-06-29
Abstract: The present invention provides improved methods for ID delivery of drugs and other substances to humans or animals. The methods employ small gange needles, especially microneedles, placed in the intradermal space to deliver the substance to the intrademial space as a bolus or by infusion. It has been discovered that the placement of the needle outlet within the skin and the exposed height of the needle outlet are critical for efficacious delivery of active substances via small gauge needles to prevent leakage of the substance out of the skin and to improve absorption within the intradermal space. The pharmacokinetics of hormone drugs delivered according to the methods of the invention have been found to be very similar to the pharmacokinetics of conventional SC delivery, indicating that ID administration according to the methods of the invention is likely to produce a similar clinical result (i.e., similar efficacy) with the advantage of reduction or elimination of pain for the patient. Delivery devices which place the needle outlet at an appropriate depth in the intradermal space and control the volume and rate of fluid delivery provide accurate delivery of the substance to the desired location without leakage.
Patent PT-1309248-E (PT)
Inventor: NSOFOR LESLIE M
IPC: A23L11/30
Filed: 2001-08-03
Abstract: A process for producing a stabilized soy beverage from dehulled-whole soybeans partially hydrolyzed with enzymes. The process generally includes: providing whole soybeans ( 100 ); activating endogenous enzymes of the whole soybeans ( 110 ), hydrolyzing proteins in the soybeans ( 120 ); and hydrolyzing carbohydrates in the soybeans ( 130 ) to form a hydrolyzed soy base ( 140 ) including proteins and carbohydrates that do not form an observable colloidal phase. A preferred process includes: providing whole soybeans; hydrating the soybeans to activate endogenous enzymes within the soybeans; dehulling the soybeans; hydrolyzing the proteins within the dehulled soybean cotyledons by incubating the cotyledons at elevated temperatures; gelatinizing the incubated cotyledons to induce coagulation of the soybean polysaccharides; milling the gelatinized cotyledons into a slurry; hydrolyzing the polysaccharides of the cotyledons with the aid of added cellulose and/or hemicellulase to form a hydrolyzed soy base; deodorizing the slurry; mixing sweeteners, flavoring, and solubilization aids with the hydrolyzed soy base; homogenizing the hydrolyzed soy base; and heat treating the hydrolyzed soy base to form a soy beverage.
Patent PT-1256437-E (PT)
Title: Method of manufacturing of infrared reflecting articles made from impact resistant plastic
Inventor: SCHARNKE WOLFGANG
IPC: B29C48/38
Filed: 2002-04-03
Abstract: A process for the production of a translucent, IR-reflective plastic element, consisting entirely or at least in part of an impact-resistant, thermoplastic plastic, containing IR-reflective particles made of a lamellar-shaped carrier pigments coated with a metal oxide and the plastic element made therefrom.
Patent PT-1412642-E (PT)
Title: System, clamping element and counter-element for the connection of profiled elements
Inventor: BASLER NORBERT
IPC: F16B5/06
Filed: 2002-08-02
Abstract: System for connecting profile elements includes a separate clamping element having a clamping plate and at least one protrusion and a separate locking element having a base plate and at least one protrusion. In an assembled state, the locking element butts against that side of the profile elements located opposite the clamping element, such that protrusions of the locking element and of the clamping element are directed toward one another. A device is utilizes to clamp the clamping element and the locking element together such that, in the assembled state, the profile elements are clamped in between the clamping element and the locking element. The device being guided centrally between the profile elements.
Patent PT-1465663-E (PT)
Title: Ready-to-use paracetamol injection solutions containing propylene glycol as the only cosolvent
Inventor: NGUYEN-XUAN THAO
IPC: A61K47/12
Filed: 2002-10-15
Abstract: The present invention refers to ready-to-use highly stable paracetamol injectable solutions, prepared by mixing paracetamol, water, propylene glycol, and a citrate buffer. (pH 4.5 to 6.5), and by heating said solution under preset conditions. The resulting solution may be stored for an extended period of time within a wide range of temperatures, with no paracetamol precipitation and/or its chemical modification.
Patent PT-1426989-E (PT)
Title: Electric motor driven hand-held tool
Inventor: STIRM MICHAEL
IPC: H01H9/06
Filed: 2003-11-11
Abstract: An electric motor driven hand-held tool, such as a drilling, hammering or screw driving tool having a tool housing within which is located an integrated switch unit (6). The switch unit (6) includes an electronic motor control unit (8), a first actuator which is actuated by a manually operable power member (4) and to which the control unit is responsive to power the motor and a second actuator (10) which is actuated by a manually operable forward/reverse member (14) and to which the control unit is responsive to drive the motor in a selected forward or reverse direction. The forward/reverse member (14) is located remotely from the switch unit (6) on a portion of the tool housing which can be seen by a user of the tool during normal operation of the tool. To facilitate this a linkage arrangement (16) is provided for actuating the second actuator (10) in response to a manual actuation of the forward/reverse member (14). The linkage (16) is pivotally mounted on a closed end of a jam pot motor casing (3). The linkage comprises a central annular portion (18) pivotally mounted on a boss (4) formed on the motor housing (3), a first upwardly extending arm (20) on which the forward/reverse lever (14) is formed and a second downwardly extending arm (22) which engages the second actuator (10). <IMAGE>
Patent PT-1485719-E (PT)
Title: Peptide epitopes common to antigens of the same multigene family
Inventor: KOSMATOPOULOS KOSTAS
IPC: G01N33/68
Filed: 2003-03-27
Abstract: The invention relates to the production of peptide epitopes common to a plurality of antigens of the same multigene family, said epitopes containing at least one common pentapeptide sequence preceded by three amino acids at the N-terminal end and optionally followed by one or two amino acids at the C-terminal end. The invention also relates to polynucleotides coding for said epitopes. Said peptides and polynucleotides can be especially used in anti-tumour immunotherapy.
Patent PT-1493441-E (PT)
Title: Therapeutic agent for food competence disorder in stomach
Inventor: UEKI SHIGERU
IPC: C07D307/68
Filed: 2003-04-08
Abstract: A therapeutic agent for impaired gastric accommodation which contains as an active ingredient a compound represented by the general formula (1):   
(wherein R 1  represents a hydrogen atom, a hydroxyl group or a halogen atom; A represents a furyl group, a thienyl group, a thiazolyl group or an oxazolyl group; R 2  and R 3  each represents an alkyl group with 1 to 5 carbon atoms; and n represents an integer of 2 to 4), or an acid addition salt thereof.
Patent PT-1663548-E (PT)
Title: Method to produce an element subject to wear, and element subject to wear thus obtained
Inventor: ANDREUSSI ALBERTO
IPC: C04B35/117
Filed: 2004-05-06
Abstract: Method to produce an element (10) subject to wear, such as a mechanical member, an abrasion or crushing tool or suchlike, comprising a metal matrix (14) and at least a core (12) of ceramic material. The method comprises a preliminary step wherein the core (12) is prepared by mixing at least a first component with a base of aluminum oxide in the form of a (a-Al2O3) with a second component comprising a eutectic compound with a base of a-Al2O3 and ZrO2, a second step wherein the core (12) is arranged in a mold, so as to define a free volume inside the mold, and a third step wherein a molten metal material is cast into the mold, to occupy the free volume so as to anchor to the core (12) and thus form a single body.
Patent PT-1931697-E (PT)
Title: Il-17a and il-17f antagonists and methods of using the same
Inventor: RIXON MARK W
IPC: A61K38/17
Filed: 2006-09-28
Abstract: The present invention relates antagonists of IL-17A and IL-17F. The antagonists of the invention are based on IL-17RC alone or on both IL-17RC and IL-17RA ("IL-17RC/IL-17RA"). Such antagonists serve to block, inhibit, reduce, antagonize or neutralize the activity of IL-17F, IL-17A, or both IL-17A and IL-17F. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. IL-17RA is a receptor for IL-17A and IL-17RC is a common receptor for both IL-17A and IL-17F. The present invention includes soluble IL-17A and IL-17F antagonists, as well as methods for using the same.
Patent PT-1977668-E (PT)
Title: A device for heating liquids by means of steam
Inventor: COCCIA ANDREA
IPC: A47J31/44
Filed: 2007-04-05
Abstract: A device for heating a liquid by means of steam comprises a body (1) having an internal convergence cavity (2) into which ducts (7, 13, 9) open for admitting a flow of liquid to be heated, for admitting a flow of steam, and for drawing off a flow of heated liquid, respectively. The direction of the heated liquid flow drawn off from the convergence cavity (2) is parallel to the direction of the flow of liquid to be heated admitted to that cavity (2) and the direction of the flow of steam is arranged transversely relative to the directions of the flows of liquid to be heated and of heated liquid.
Patent PT-2028278-E (PT)
Title: Rna sequence-specific mediators of rna interference
Inventor: TUSCHL THOMAS
IPC: C12N15/09
Filed: 2001-03-30
Abstract: Double-stranded RNA (dsRNA) induces sequence-specific post-transcriptional gene silencing in many organisms by a process known as RNA interference (RNAi). Using a Drosophila in vitro system, we demonstrate that 19-23 nt short RNA fragments are the sequence-specific mediators of RNAi. The short interfering RNAs (siRNAs) are generated by an RNase III-like processing reaction from long dsRNA. Chemically synthesized siRNA duplexes with overhanging 3' ends mediate efficient target RNA cleavage in the lysate, and the cleavage site is located near the center of the region spanned by the guiding siRNA. Furthermore, we provide evidence that the direction of dsRNA processing determines whether sense or antisense target RNA can be cleaved by the produced siRNP complex.
Patent PT-2111569-E (PT)
Title: Closed-loop control method and closed-loop control device with multi-channel feedback
Inventor: KRAH JENS ONNO
IPC: G05B11/28
Filed: 2008-07-09
Abstract: A method of closed-loop controlling determines a first feedback variable by sampling a control variable and a second feedback variable by averaging the control variable, compares the first and second feedback variables with a command variable, and sets the control variable on the basis of the comparing result so that the control variable follows a command variable.
Patent PT-2307938-E (PT)
Title: Flow control system
Inventor: ULENS JAN
IPC: E03B7/00
Filed: 2008-12-22
Abstract: The present invention relates to a flow control system for controlling a flow of a medium passing through a pipe part of a pipe system via which the medium is distributed from a common source to a plurality of consumer devices. The flow control system comprises a flow sensor for sensing an actual medium flow through the pipe part, a controller in communicative connection with the flow sensor and provided for evaluating the electrical signal indicative of the sensed actual medium flow with a value representing a set medium flow and an orifice adjusting system in communicative connection with the controller and provided for adjusting the adjustable orifice in response to the control signal received from the controller. The flow sensor is arranged outside the flow chamber and has a static measurement principle based on a wave propagating in the medium.
Patent PT-2261378-E (PT)
Title: Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins
Inventor: GARRY ROBERT F
IPC: C12N/
Filed: 2004-11-03
Abstract: The present invention relates to a method of preventing or inhibiting viral infection of a cell and/or fusion between the envelope of a virus and the membranes of a cell targeted by the virus (thereby preventing delivery of the viral genome into the cell cytoplasm, a step required for viral infection). The present invention particularly relates to the families of RNA viruses, including the arenaviruses, coronaviruses, filoviruses, orthomyxoviruses, paramyxoviruses, and retroviruses, having Class I membrane fusion proteins as the fusion proteins that mediate this fusion process. The present invention provides for a method of identifying a conserved motif or domain called the fusion initiation region (FIR) in these viruses. The present invention further provides for methods of preventing infection by such viruses, by interfering with their FIR. The present invention further provides for methods of treatment and prophylaxis of diseases induced by such viruses.
Patent PT-672136-E (PT)
Inventor: YAP SING-HIEM
IPC: C07K16/00
Filed: 1993-07-06
Abstract: The invention relates to a mammalian nonhuman transgenic animal liable to be infected by HBV and moreover liable to suffer from hepatocellular damage, caused by the constitutive or inducible expression of the human endonexin II gene or by the nucleotide sequence coding for its muteins or fragments, the said gene or the said nucleotide sequence being introduced into such a transgenic animal as a model for testing potential drugs.
Patent PT-682036-E (PT)
Inventor: RICHARD LISOWSKY DR
IPC: C07F17/00
Filed: 1995-04-26
Abstract: The prodn. of methyl-transition metal cpds. of formula (Q)m(CpRa)(Cp'R'a')M(CH3)nX2-n (1) comprises reacting corresp. halo-transition metal cpds. (2) with Me3Al in a hydrocarbon solvent, opt. at elevated temp., adding alkali and/or alkaline earth metal fluoride (3) and removing the Al fluoride complex which is formed. In (1) Cp = cyclopentadienyl, indenyl or fluorenyl; R, R' = alkyl, phosphine, amine, alkyl-ether or aryl-ether gps. with O ≤ a ≤ 5 and O ≤ a' ≤ 5; Cp' = as for Cp. or Cp' = N with R = alkyl or aryl with a' = 1; Q = single- or multi-membered bridge -(ZR<1>R<2>)b- between Cp and Cp' (with R<1>, R<2> = H, 1-10C alkyl or 6-10C aryl; Z = C, Si or Ge; b = 1, 2 or 3); M = Gp. 3-6 transition metal, esp. Ti, Zr or Hf; X = halogen, pref. Cl or Br; n = 1 or 2; and m = 0 or 1. Pref. the reaction is carried out at 20-120 degrees C in opt. substd. aliphatic or aromatic hydrocarbons with b.pts. of 50-150 degrees C, using NaF or KF as the metal fluoride (3). The mole ratio of (2):(Me3Al):(3) = 1:1:1 in the case of mono-methyl cpds. (1), or 1:2:2 in the case of di-methyl cpds. (1).
Patent PT-702915-E (PT)
Inventor: SCHRODER GERHARD
IPC: A47B88/00
Filed: 1995-07-24
Abstract: The front panel (4) of the drawer is attached to two rear mounting brackets (7) by threaded fasteners. Each bracket is clipped to an intermediate mounting element (8) which incorporates screw adjustment for vertical alignments. The mounting can swivel about a vertical axis. The intermediate mounting element is clamped to the support bracket (6) which supports the side of the drawer on the drawer rail.   The vertical adjusting screw (17) adjusts the relative setting of the intermediate mounting element on the drawer structure. The swivel adjuster (14) is set through the mounting element and swivels it to either side.
Patent PT-765394-E (PT)
Inventor: SCHNEIDER PALLE
IPC: C12N1/15
Filed: 1995-05-31
Abstract: The present invention relates to isolated nucleic acid constructs containing a sequence encoding a Myceliophthora laccase, and the laccase proteins encoded thereby.
Patent PT-832094-E (PT)
Inventor: ZASLOFF MICHAEL
IPC: A61P31/10
Filed: 1996-06-07
Abstract: Aminosterol compounds are described that are useful as inhibitors of the sodium/proton exchanger (NHE). Methods of using such aminosterols compounds are also enclosed, including those employing compounds that are inhibitors of a spectrum of NHEs as well as those using compounds that are inhibitors of only one specific NHE. Advantageous screening techniques and essays for evaluating a compound's therapeutic activity are also disclosed.
Patent PT-796858-E (PT)
Inventor: BELL ANDREW SIMON
IPC: A61P25/04
Filed: 1997-02-06
Abstract: An antifungal compound of formula (I): <CHEM> or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of either entity, wherein X is CH or N; R<1> is phenyl subsituted with 1 to 3 substituents each independently selected from halo and CF3; R<2> is (hydroxy)C1-C4 alkyl, CONH2, S(O)m(C1-C4 alkyl), Ar or Het; m is 1 or 2; Ar is phenyl optionally monosubstituted with halo or CF3; and Het is a C-linked 6-membered nitrogen-containing aromatic heterocyclic group containing 1 or 2 nitrogen atoms, or a C- or N-linked 5-membered nitrogen-containing aromatic heterocyclic group containing from 2 to 4 nitrogen atoms, wherein either of said heterocyclic groups is optionally substituted with C1-C4 alkyl or (C1-C4 alkoxy)methyl.
Patent PT-1001944-E (PT)
Inventor: MIGNANI SERGE
IPC: C07D213/81
Filed: 1998-07-15
Abstract: The invention concerns pyrazine derivatives of formula (1) in which a pharmaceutical composition comprising at least one compound of formula:in whichR represents a nitrogen atom, R1 and R3 each represent the same radical selected from the group consisting of -CO-NR5R6, -CO-N(CH(CH2OH)2)2, -CO-N(CH2OH)2, -CO-N(CH2-CH(CH2OH)2)2, -CO-N(CH2-(CHOH)n-CH2OH)2 in which n is equal to 0, 1, 2, 3 or 4, -CH2-O-R6, -NR5-CO-R6, -CH2-NR5R6, -CH2-N(CH2OH)2, -CH2-N(CH2-(CHOH)y-CH2OH)2 in which y is equal to 0, 1, 2, 3 or 4, -CH2-N(CH(CH2OH)2)2 and -CH2-N(CH2-CH(CH2OH)2)2 and R2 and R4 each represents a hydrogen atom,R5 represents a hydrogen atom or an alkyl radical,R6 represents a radical -CH2-(CHOH)m-CH2OH in which m is equal to 0, 1, 2, 3 or 4, -alk-O-alk-CH2OH, -alk-O-alk, -CH(CH2OH)2, -C(CH2OH)3, -C(CH3) (CH2OH)2, -CH2-CH(CH2OH)2 or -CH(CH2OH)-(CHOH)x-CH2OH in which x is equal to 1, 2, 3 or 4, alk represents an alkyl radical, the alkyl radicals containing, unless otherwise stated, 1 to 6 carbon atoms in a straight or branched chain, stereoisomers thereof and salts thereof with an inorganic or organic acid and their preparation.
Patent PT-976681-E (PT)
Inventor: OKADA AKIRA
IPC: C01F7/785
Filed: 1999-07-26
Abstract: Novel, fine particulate synthetic chalcoalumite, process for preparation thereof, and a heat insulating agent and agricultural film containing said fine, particulate synthetic chalcoalumite. The above objects are met by synthetic chalcoalumite represented by formula (1) below: (M1<2+>)a-x(M2<2+>)xAl<3+>4(OH)b(A<n->)c . mH2O     (in which M1<2+> stands for Zn<2+> or Cu<2+>, M2<2+> is at least one divalent metal ion selected from Ni <2+>, Co<2+>, Cu<2+>, Zn<2+> and Mg<2+>, a is 0.3 < a < 2.0 (with the proviso that M1 and M2 are not the same),   x is 0 </= x < 1.0,   b is 10 < b < 14, A<n-> is at least one selected from SO4<2->, HPO4<2->, CO3<2->, SO3<2->, HPO3<2->, NO3<->, H2PO4<->, Cl<->, OH<-> and silicic ion,   c is 0.4 < c < 2.0 and   m is 0-4), which has an average secondary particle diameter of not more than about 3  mu m and a BET specific surface area of not more than about 30 m<2>/g; resin compositions containing the same; and agricultural film composed of said resin compositions.
Patent PT-1095182-E (PT)
Inventor: SANDISON MALCOLM
IPC: D21B1/36
Filed: 1999-03-08
Abstract: The invention provides a process and apparatus for the treatment and recovery of fiberboard and particle board waste. Waste fiberboard and particle board is fed into a steam chamber and steam treated with steam under pressure from a steam generator. When the steam treatment is completed any effluent and excess steam are evacuated from the chamber and the steam treated waste is passed through a rotating trommel. Woodfibers and woodchips pass through the screens of the trommel and are collected for drying and further processing. Waste material, such as melamine coatings, passes through the trommel for collection and disposal. The collected woodfiber and woodchips can be processed for reuse in paper, cardboard or particle board manufacture or as mulch and other ground cover material.
Patent SG-85191-G (SG)
Title: Disinfectant polymeric coatings for hard surfaces
IPC: A01N25/24
Filed: 1991-10-11
Abstract: Liquid disinfectant compositions are disclosed which can be used to surface-coat suhstrates with polymeric films which are adherent, water-resistant and which can impart prolonged germicidal properties to the treated surfaces. In one embodiment, the composition comprises a solution of a minor amount of a film-forming, water-insoluble copolymer in a major amount of a volatile solvent, said copolymer comprising (a) monomer having a hydrophilic functional group, and (b) about 0.5-80 mol-% of said copolymer of an alpha, beta-unsaturated carboxylic acid ester selected from aromatic esters, cycloalkyl esters and mixtures thereof, and an amount of a germicidal agent effective to impart prolonged antimicrobial properties to the film.
Patent SG-98190-G (SG)
Title: Electrodes,electro-chemical cells containing said electrodes,and process for forming and utilizing such electrodes
IPC: C25C7/02
Filed: 1990-12-10
Abstract: The invention includes electrodes having a plurality of fibers wherein an essentially continuous metallic coating of high bond strength extends over at least a portion of each fiber, and wherein the fibers provide a large surface area. The electrodes of the invention have an efficient electrical connection at their terminals comprising fiber/metal matrices which provide the desired connections to the terminals without damage to the fibers. The fiber metal matrices also provide excellent electrical contact between all of the fibers, and inhibit wicking of the electrolyte or process stream into the electrical connections. Where the fibers are coated along a substantial portion of their length, they also have a high electrical conductivity. The invention further includes electro-chemical cells, and processes for forming and utilizing the electrodes and cells.
Patent IE-890128-L (IE)
Title: Method of producing 2-substituted oximino-3-oxobutyric¹acids.
IPC: C07C67/00
Filed: 1989-01-17
Abstract: An advantageous method of producing in large amounts on a commercial scale 2-substituted oxyimino-3-oxobutyric acids, which are useful as intermediates in the synthesis of e.g. aminothiazole cephalosporins, is characterized by reacting a tert-butyl 2-substituted oxyimino-3-oxobutyrate with a hydrogen halide in an anhydrous organic solvent.
[EP0325183A2]