baber/WOPTO huggingface dataset:
Patent AU-2020319652-A1 (AU)
Title: 6,7-dihydro-5H-pyrido[2,3-c]pyridazine derivatives and related compounds as Bcl-xL protein inhibitors and pro-apoptotic agents for treating cancer
Inventor: NOVAK TIBOR
IPC: A61P35/00
Filed: 2020-07-28
Abstract: The present invention discloses 6,7-dihydro-5H-pyrido[2,3- c]pyridazine, 1,2,3,4-tetrahydroquinoline, 1H-indole, 3,4- dihydro-2H-1,4-benzoxazine, 1H-pyrrolo[2,3-b]pyridin-1-yl, 7H- pyrrolo[2,3-c]pyridazine, 5H,6H,7H,8H,9H-pyridazino[3,4-b]azepine derivatives and related compounds of formula (I) as Bcl-xL protein inhibitors for use as pro-apoptotic agents for treating cancer, autoimmune diseases or immune system diseases. Formula (I). The description discloses the preparation of exemplary compounds (e.g. pages 113 to 354 examples 1 to 221) as well as pharmacological studies with relevant data (e.g. pages 355 to 367; examples A to E; tables 1 to 5). Exemplary compounds are e.g. 2-{6-[(1,3-benzothiazol-2-yl) amino]-1,2,3,4-tetrahydroquinolin-1-yl}-1,3-thiazole-4-carboxylic acid (example 1) or e.g. 3-{1-[(adamantan-1-yl)methyl]-5- methyl-1H-pyrazol-4-yl}-6-{3-[(1,3-benzothiazol-2-yl)amino]-4- methyl-5H,6H,7H,8H-pyrido[2,3-c]pyridazin-8-yl]pyridine-2-carboxylic acid (example 24).
Patent AU-2020326763-A1 (AU)
Title: Portable articulating ultrasonic inspection
Inventor: KOCUREK CHRISTOPHER GEORGE
IPC: G01N17/02
Filed: 2020-08-05
Abstract: Methods of assessing internal features of oilfield equipment including elbows, connections, valves, branches, olets, and other structures include the methods and apparatus for determining the physical geometric boundaries of oilfield structures using an automated articulating arm with an external laser scanner and an ultrasonic probe.
Patent AU-2020357834-A1 (AU)
Title: Wireless teeth whitening system
Inventor: LEVINE JONATHAN B
IPC: A61C19/06
Filed: 2020-09-30
Abstract: A wireless teeth whitening system includes a mouthpiece that is devoid of any electrical circuitry so that it may easily be cleaned and sterilized. A control module may be coupled to the mouthpiece. This module has an electrical circuit board with LEDs and heating elements mounted on it. When the control module is coupled to the mouthpiece, the system may be used to whiten teeth. The control module includes a battery that may be inductively charged, and may be wirelessly controlled via Bluetooth from a mobile application.
Patent AU-2020359872-A1 (AU)
Title: Engineered human immune cells, preparation method and application thereof
Inventor: LI PENG
IPC: A61P31/18
Filed: 2020-09-27
Abstract: Provided are engineered human immune cells, a preparation method, and an application thereof. The engineered human immune cells are immune killer lymphocytes induced by reprogramming of human T cells, from which the BCL11B gene is deleted. The engineered human immune cells retain markers and functions of the T cells from which they are derived and have markers and functions of NK cells. The reprogrammed engineered human immune cells can be used to prepare drugs for treating tumors and infectious diseases.
Patent AU-2020361079-A1 (AU)
Title: Treatment
Inventor: RINALDI CARLO
IPC: A61P21/00
Filed: 2020-10-02
Abstract: The present invention relates to treatment of AR-related disorders by modulating the levels of AR2, which is a naturally occurring AR variant and is capable of modulating AR transcriptional activity.
Patent AU-2020370140-A1 (AU)
Title: Material transfer vehicle with movable operator's platform
Inventor: NEISEN MATTHEW
IPC: B62D33/063
Filed: 2020-10-21
Abstract: A material transfer vehicle has a frame, a front end including an asphalt paving material receiving device, and rear end including a discharge conveyor which is adapted to convey asphalt paving material to the receiving hopper of an asphalt paving machine. An operator's station includes an operator's platform on which is mounted an operator's seat. The operator's platform is moveable between a travel position that is entirely within the outer periphery of the material transfer vehicle and an operating position that locates the operator's seat at least partially outside the outer periphery of the material transfer vehicle.
Patent AU-2020370606-A1 (AU)
Title: Whole virus quantum mechanical tunneling current and electronic sensors
Inventor: TABIB-AZAR MASSOOD
IPC: H01L29/78
Filed: 2020-10-26
Abstract: A field effect transistor (FET) biosensor (100) for virus detection of a selected virus (102) within a sample volume is disclosed. The FET comprises a semiconductor substrate (106), a source electrode (108) and drain electrode (110) on the substrate (106), the electrodes spaced to form a channel (114). A gate electrode (112) carried on the substrate (106) and located in the channel (114) between the source electrode (108) and drain electrode (110). An insulating layer (116) is coupled to a top surface of the gate electrode (112) and a bottom surface of the source electrode (108) and drain electrode (110), with the open channel (114) above the insulating layer (116). A channel material (118) is coupled to the insulating layer (116). Molecular recognition groups (120) are oriented within the open channel (114) to bind to the channel material (118) and with the selected virus (102) to enable a detection of the selected virus (102) by the FET biosensor (100) based on a change in drain-source current at a selected gate voltage.
Patent AU-2020371258-A1 (AU)
Title: Stove, control system, and method for controlling the same
Inventor: WELLS ALEXANDER
IPC: F23L3/00
Filed: 2020-10-09
Abstract: A stove (1) having a combustion chamber (2) supplied by one or more air supply paths (9, 14, 16). One or more valves (11, 15, 17) are provided for controlling airflow through the one or more air supply paths (9, 14, 16). A temperature sensor (4) is used to determine the air temperature associated with the combustion chamber (2), and a flame sensor (3) is used to determine the burn intensity of a fuel in the combustion chamber (2). A controller (5) controls the one or more valves (11, 15, 17) to adjust the airflow through the one or more air supply paths (9, 14, 16) based on inputs from the flame and temperature sensors (3, 4).
Patent AU-2020381646-A1 (AU)
Title: Method of detection of fibrin clots
Inventor: BAUTOVICH GEORGE
IPC: C12N15/10
Filed: 2020-11-12
Abstract: The use of aptamers for the detection of fibrin and/or blood clots and methods to produce such aptamers.
Patent AU-2020394317-A1 (AU)
Title: Augmented aerospike nozzle, engine including the augmented aerospike nozzle, and vehicle including the engine
Inventor: LAPSA ANDREW
IPC: F02C7/04
Filed: 2020-08-27
Abstract: An augmented aerospike nozzle includes a throat, a centerbody extending aft of the throat, an inner expansion surface defined by the centerbody, an outer expansion surface outboard of the inner expansion surface, and an expansion cavity defined between the inner expansion surface and the outer expansion surface. An engine includes a high pressure chamber and the augmented aerospike nozzle. A vehicle for supersonic flight includes the engine with the augmented aerospike nozzle.
Patent AU-2020412776-A1 (AU)
Title: Variable density spatial scanning and electro-mechanically controlled ultrasound scan density device
Inventor: SCHAFER MARK E
IPC: A61B8/00
Filed: 2020-12-23
Abstract: An ultrasound system includes a computing device, a transducer configured to angulate through a scan region in response to a mechanical drive system that converts rotational motion generated by a motor into angular motion that angulates the transducer through the scan region, and an encoder configured to detect a rotational position of a shaft of the motor. The computing device is configured to determine an angular position of the transducer within the scan region based on the rotational position of the shaft detected by the encoder, and control generation of scan lines from the transducer based on a pulse firing pattern of scan lines to produce a predefined sequence of scan line densities across the scan region and the determined angular position of the transducer.
Patent WO-2022109685-A1 (WO)
Title: Complex materials
Inventor: LI DONGYANG
IPC: C22C29/02
Filed: 2021-11-30
Abstract: A complex carbide for mining and mineral processing applications that are subject to severe additional metal, with the additional metal being a transition metal.
Patent AU-2021201161-A1 (AU)
Title: Robotic Fire Fighter
Inventor: SCHEMBRI JOSEPH PAUL
IPC: A62C99/00
Filed: 2021-02-23
Abstract: A device for fighting a fire by spreading material such as dirt onto the fire comprising 
including a rotating drum to collect material into a chamber and a rotating blade to move 
the material through the chamber and out through a directable chute. A fan assists the 
material through the chute. The rotating drum includes either mulching blades, hoeing 
blades or scoops to gather the material. The device is used in conjunction with a motive 
device such as a tractor or a remotely controlled drive unit.
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Figure 1
Patent AU-2021201790-A1 (AU)
Title: Non-hormonal steroid modulators of NF-kB for treatment of disease
Inventor: MCCALL JOHN M
IPC: A61P29/00
Filed: 2021-03-23
Abstract: The present invention relates to compounds and methods which may be useful as 
treatments of diseases.
Patent AU-2021214764-A1 (AU)
Title: Platform for native liquid chromatography-mass spectrometry
Inventor: WANG SHUNHAI
IPC: G01N30/84
Filed: 2021-01-29
Abstract: Disclosed are native liquid chromatography-mass spectrometry systems and methods of use. A native liquid chromatography-mass spectrometry system can include a liquid chromatography system capable of separating a sample; and an electrospray ionization mass spectrometry (ESI-MS) system in fluid communication with the liquid chromatography system, wherein the ESI-MS system comprises a multi-nozzle electrospray ionization emitter and a system for modifying a desolvation gas and a mass spectrometer, wherein the mass spectrometer is configured to receive ions and characterize mass to charge ratio of ions.
Patent AU-2021221889-A1 (AU)
Title: Method for producing allulose crystals
Inventor: IYER KRISHNAN VISWANATHAN
IPC: C07H1/06
Filed: 2021-08-26
Abstract: Allulose crystals are efficiently produced from an allulose syrup using seed crystals.
Patent AU-2021232740-A1 (AU)
Title: Anchor assembly for fastener
Inventor: MCDUFF PIERRE
IPC: F16B13/08
Filed: 2021-09-15
Abstract: An anchor assembly for walls comprises a toggle member and a strap member 
pivotally mounted together, and a locking member. In a first position thereof, the 
toggle member is aligned with the strap member for insertion through the wall, 
whereas in a second position thereof, the toggle member extends behind the wall 
at an angle relative to the strap member which extends from the toggle member 
through the hole in the wall. The locking member is adapted to be displaced along 
the strap member until it engages the wall and to be locked on the strap member 
to prevent the locking member from displacing away from the toggle member.  
Therefore, the locking member and the toggle member are connected by the 
strap member and imprison the wall by abutting respectively the visible and 
hidden sides thereof. A fastener introduced through the locking member and the 
wall threadably engages an opening defined in the toggle member.
Patent AU-2021236463-A1 (AU)
Title: Agricultural enterprise management method and system
Inventor: SCHMALTZ REMI
IPC: G06Q50/02
Filed: 2021-09-21
Abstract: AGRICULTURAL ENTERPRISE MANAGEMENT METHOD AND SYSTEM 
ABSTRACT 
A computer-implemented cloud-based agricultural enterprise management system 
and methods. The system comprises a plurality of modular components for receiving and 
processing data pertaining to agricultural production of commodities by an agricultural 
producer and for centralizing and storing the received and/or processed data in a single 
cloud-based database. The producer can provide to one or more third-party suppliers 
and/or service providers, authorized but restricted access to selected components of their 
agricultural enterprise management system and cloud-based database so that together, the 
producer, suppliers and service providers can effectively and cost-efficiently plan and 
manage the delivery of products and services during a crop production cycle, and the sale 
of harvested agricultural commodities. Separate modular components may be provided for 
inputs exemplified by agronomy data, crop production inputs data, crop growth and 
performance tracking, commodity market data, weather monitoring and forecasting, farm 
equipment maintenance, enterprise management overhead components.
Patent AU-2021248643-A1 (AU)
Title: Antibody molecule-drug conjugates and uses thereof
Inventor: PLANTE OBADIAH JOSEPH
IPC: A61P31/04
Filed: 2021-04-02
Abstract: Antibody molecule-drug conjugates (ADCs) that specifically bind to lipopolysaccharides (LPS) are disclosed. The antibody molecule-drug conjugates can be used to treat, prevent, and/or diagnose bacterial infections and related disorders.
Patent AU-2021258062-A1 (AU)
Title: Processing protein
Inventor: MEAD DAMIEN GEOFFREY
IPC: C07K14/79
Filed: 2021-10-14
Abstract: t-IlU IRUI I 
ABSTRACT 
A method comprising feeding MF feedstock to a cross-flow microfilter. The MF 
feedstock comprises at least 5% protein solids and has a conductivity of less than 
10 mS/cm.
Patent AU-2021262745-A1 (AU)
Title: Anti-CD40 antibody combination treatment for cancer
Inventor: SCHMITT MICHAEL
IPC: A61K39/395
Filed: 2021-04-27
Abstract: This disclosure relates to methods of treating cancer using a combination of an anti-CD40 antibody such as SEA-CD40, and an anti-PD-1 antibody such as pembrolizumab. The treatment can further include a chemotherapy.
Patent AU-2021286309-A1 (AU)
Title: Parameter encoding and decoding
Inventor: BOUTHÉON ALEXANDRE
IPC: G10L19/008
Filed: 2021-12-14
Abstract: Parameter Encoding and Decoding 
Abstract 
There are disclosed several examples of encoding and decoding technique. In particular, an audio 
synthesizer (300) for generating a synthesis signal (336, 340, yR) from a downmix signal (246, x), 
comprises: an input interface (312) for receiving the downmix signal (246, x), the downmix signal 
(246, x) having a number of downmix channels and side information (228), the side information 
(228) including channel level and correlation information (314, , x) of an original signal (212, y), 
the original signal (212, y) having a number of original channels; and a synthesis processor (404) 
for generating, according to at least one mixing rule, the synthesis signal (336, 340, yR) using: 
channel level and correlation information (220, 314, , x) of the original signal (212, y); and 
covariance information (Cx) associated with the downmix signal (324, 246, x).
Patent AU-2021298800-A1 (AU)
Title: Tetrazole derivatives as TRPA1 inhibitors
Inventor: BINDER FLORIAN PAUL CHRISTIAN
IPC: A61K31/506
Filed: 2021-06-25
Abstract: The present disclosure provides certain tetrazole derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds.
Patent AU-2021306236-A1 (AU)
Title: Nasal hygiene compositions, antimicrobial treatments, devices, and articles for delivery of same to the nose, trachea and main bronchi
Inventor: DEVLIN THOMAS E
IPC: A61Q19/10
Filed: 2021-07-02
Abstract: Salt-based non-therapeutic hygienic formulations or compositions or therapeutic formulations or compositions, for example those rich in calcium, are effective against airborne pathogens and toxins, suppressing shedding, for instance by increasing a surface viscoealasticity of airway lining fluid. Associated apparatus, methods and articles are used to deliver salt-based non-therapeutic hygienic formulations or compositions as hygienic treatments to the upper respiratory tract. Associated apparatus, methods and articles are used to deliver salt-based therapeutic antimicrobial formulations or compositions to the upper respiratory tract. For example, nasal delivery of calcium-rich salines with aerosol droplet size of around 10 μm (e.g., 7 μm -15 μm, or more preferably 9 μm - 10 μm) may advantageously limit distribution to the nose and upper airways of the respiratory tract, suppressing bioaerosol generation. A nebulizer may deliver the aerosol into free space, or into a partially enclosed volume, and the composition naturally inspired by one or more subjects.
Patent AU-2021311673-A1 (AU)
Title: PD-L1/LAG-3 bispecific antibody preparation, and preparation method therefor and use thereof
Inventor: Yao tianyi
IPC: A61K9/08
Filed: 2021-07-22
Abstract: Provided are a pharmaceutical preparation containing a PD-L1/LAG-3 double antibody, a buffer, a stabilizer, a surfactant and a chelating agent, and the corresponding therapeutic or preventive use thereof.
Patent AU-2021312899-A1 (AU)
Title: Condiment dispenser
Inventor: LEECH GREGG
IPC: F04B53/10
Filed: 2021-07-23
Abstract: A condiment dispensing pump system is provided that includes a valve chamber and a valve retainer having a first portion defining a valve cavity and a second portion for coupling to an inlet flow path. A one-way valve is removably insertable into the valve cavity. The one-way valve includes a tether portion coupled to the second portion of the valve retainer such that the one-way valve is removable from the valve cavity while still tethered to the valve retainer. The condiment dispensing pump system includes a spout having a first end fluidly coupled to the valve cavity and a second end opposite the first end. A dispensing nozzle is removably attached to the second end of the spout, the dispensing nozzle being tethered to the spout tube such that when the dispensing nozzle is detached from the second end of the spout the dispensing nozzle remains tethered to the spout tube.
Patent AU-2021369448-A1 (AU)
Title: Proteins for the detection of schistosoma infection
Inventor: LOUKAS ALEX
IPC: G01N33/569
Filed: 2021-10-27
Abstract: The invention pertains to the field of diagnostic tools for the detection of
Patent AU-2021372955-A1 (AU)
Title: Multistage continuous transportation system
Inventor: WANG HONG
IPC: E21C35/20
Filed: 2021-04-27
Abstract: The present disclosure relates to the technical field of coal mines, specifically to a 
multistage continuous transportation system. The multistage continuous transportation system 
includes an excavation device, an anchor conveyor, a first belt conveyor, a self-moving bridge 
5 loader and a second belt conveyor. A second end of the excavation device is lapped on the 
anchor conveyor, two ends of the first belt conveyor are respectively provided with a loading 
portion and an unloading portion, the loading portion is connected with a second end of the 
anchor conveyor, a first traveling wheel assembly is provided at a lower end of the unloading 
portion, and lapped on the self-moving bridge loader so that the first belt conveyor moves in a 
10 length direction of the self-moving bridge loader. A second traveling wheel assembly is 
provided at a second end of the self-moving bridge loader, and lapped on the second belt 
conveyor so that the self-moving bridge loader moves in a length direction of the second belt 
conveyor. The multistage continuous transportation system according to the embodiment of 
the present disclosure has the advantages of high strength, convenient assembly and 
15 disassembly, convenient transfer and the like.
Patent AU-2021373335-A1 (AU)
Title: Hica for use in prophylaxis and/or treatment of a disease or condition involving degradation of cartilage and/or disruption of cartilage homeostasis and/or integrity
Inventor: SORSA TIMO
IPC: A61P19/02
Filed: 2021-11-05
Abstract: 2-Hydroxy-isocaproic acid (HICA), or an ester or amide derivative, an enantiomer or a pharmaceutically acceptable salt thereof, for use in prevention and/or treatment of a disease or condition involving degradation of cartilage and/or disruption of cartilage homeostasis and/or integrity is disclosed.
Patent AU-2021377725-A1 (AU)
Title: A modular electricity generation system
Inventor: HOOKEY SCOTT
IPC: F03B17/06
Filed: 2021-11-10
Abstract: The present invention relates to a modular electricity generation system. The system includes a plurality of water turbine modules for generating electricity. The modules are suitable for serially arranging to form an expansive row or line across water. Advantageously, the system harnesses the "blue energy" of moving water to generate electricity.
Patent AU-2021379834-A1 (AU)
Title: Tetraazadodecane based chelating agents for separation of rare earth elements and method therefor
Inventor: POLASEK MILOSLAV
IPC: C01F17/271
Filed: 2021-11-12
Abstract: The present invention relates to the use of compounds of general formula (I) for separations of rare earth elements (lanthanides) by precipitation, wherein R
Patent AU-2021407414-A1 (AU)
Title: Detection and recovery of metals from ore
Inventor: ACKERMAN DEAN JOHN
IPC: C22B1/00
Filed: 2021-12-21
Abstract: Method and apparatus are provided to select target metal particles from aggregate ore. A feed stream of aggregate is directed along a path and a higher density portion is segregated therefrom. Detectors are arranged in-line and along the flow of the higher density portion. High resolution detection of a target particles within the feed stream triggers ejection of a select portion of the feed stream and target particle as a concentrate and the balance continues to a further phase of detection/ejection. The concentrate is processed in further stages or collected as product. Multiple parallel detector/ejectors across the path can isolate target particles and minimize the ejected gangue portion associated therewith. Dry or hydrodynamic transport of the feed stream is available determined by aggregate characteristics. A compact footprint of the apparatus is achieved with arcuate paths and multi-level conveyance whilst low energy requirements enables use in artisan installations.
Patent AU-2021415906-A1 (AU)
Title: Stable coronavirus proteins and vaccine compositions thereof
Inventor: ELLIS DANIEL
IPC: C07K14/165
Filed: 2021-06-15
Abstract: Provided herein are compositions and methods comprising mutated coronavirus "S" spike proteins or receptor binding domains thereof that have an increased expression level, yield and stability compared to its corresponding native or wild-type coronavirus spike protein under the same expression, culture or storage conditions. These mutated spike proteins can be used for generating a protein-based vaccine against one or more coronaviruses.
Patent WO-2023272343-A1 (WO)
Title: Improved feedback control of neuromodulation device
Inventor: SINGLE PETER SCOTT VALLACK
IPC: A61B5/11
Filed: 2022-06-28
Abstract: There is provided a method of controlling a neural stimulus. The neural stimulus is defined by at least one stimulus parameter. The method comprises generating a neural stimulus for application to a neural tissue of a patient in accordance with a stimulus parameter, at a first stimulus intensity level, and measuring a response of the neural tissue, the response being evoked by the neural stimulus. The method further comprises determining a second stimulus intensity level, based on an activation plot intercept point, the first stimulus intensity level, the measured response of the neural tissue and a target recruitment level, and adjusting the at least one stimulus parameter to the second stimulus intensity level.
Patent AU-2022200120-A1 (AU)
Title: A Security Screen Assembly
Inventor: BLAKEMORE BEAU
IPC: E06B5/11
Filed: 2022-01-10
Abstract: The present invention is a security screen assembly for a door or window. The assembly 
comprises a frame with a reinforced lip, a mesh, a plastic insulator to insulate the frame from the 
mesh and a retaining wedge to hold the mesh in the frame. The characterising feature of the 
invention is that the mesh has cut and punched indentations which abut against the reinforced lip 
within the plastic insulator to prevent the mesh being withdrawn from the frame once the 
retaining wedge is in place.