baber/WOPTO huggingface dataset:
Patent KR-20000034187-A (KR)
Title: Preparation method for molten pig iron heat insulator in furnace process work
Inventor: KIM GAB YEOL
IPC: C21B7/00
Filed: 1998-11-28
Abstract: PURPOSE: A preparation method for molten pig iron heat insulator in furnace process work which can be mass produce heat insulator, increase the heat insulation capability by causing exothermic reaction between heat insulator and molten material, and reduce environmental problem such as air pollution by incorporating its own moisture is provided, by mixing carbon-containing wet sludge and carburized cokes in a certain ratio. CONSTITUTION: A preparation method for molten pig iron heat insulator in furnace process work is characteristically using carbon-containing wet sludge spun out from water treatment process of wet-type dust remover in furnace process(100) and carburized cokes generated during smashing process in cokes production process(120). The method includes the following steps: transferring(130) carbon-containing wet sludge of which moisture is adjusted to 4% or less in an agitator(110) and carburized cokes generated from cokes process to molten pig iron heat insulator processing site(140); mixing(150) the carbon-containing wet sludge and carburized cokes in the ration of 30: 70 in volume; smashing(160) the mixtures to have 1-3mm of granular diameter in order to obtain heat insulating material; drying(170) the smashed heat insulating material to moisture content of 2-3%; and packaging(180) the powder type heat insulating material to use for furnace work.
Patent KR-20000038449-A (KR)
Title: Portable master controller of master control system
Inventor: SONG JAE BOK
IPC: B25J11/00
Filed: 1998-12-07
Abstract: PURPOSE: A portable master controller of a tele-robot system is provided to perform master control as well as to realize the information to the change of working environment with tele-presence. CONSTITUTION: An encoder motor is driven through the interlock of bevel gears as each rotary plate(120,220,320,420) rotates centering on support plates(110,210,310,410) respectively. The position of a worker and driving data is transferred to the spot to control a slave robot. On the contrary, the worker is able to realize the transferred data at the spot if the motor is driven depending on the data.
Patent KR-20000038493-A (KR)
Title: Method for bus cycle stabilization
Inventor: KIM HYEONG SUP
IPC: G06F13/40
Filed: 1998-12-07
Abstract: PURPOSE: A method for bus cycle stabilization is disclosed to stabilize the bus cycle of main board and several sub boards by securing device access time when main board's clock speed increases and to safely operate without being effected by the processor's clock speed. CONSTITUTION: A method for bus cycle stabilization is composed of external device access logic(100), external bus cycle response signal detector(200), anti-error movement external bus cycle response signal detector(300), bus cycle delayer(400), and selector(500). (200) comprises of an inverter(201), which generates clock input signal, and D Flip flop(202) that receives and latches external access signal. (300) comprises of second D Flip flop(301) that receives and latches external bus cycle response signal. (400) includes N number of D Flip flop(401¯403) that receives external access signal and delays the signal for N period. When (100) causes processor to access an address outside of main board's device address map, it activates external access signal, reverses external bus cycle's response signal, uses (202)'s clock as rising, and creates a second bus response signal, which becomes inactive at the address strobe's inactivation point.
Patent KR-19990071435-A (KR)
Title: 공기조화장치의 압축기 제어시스템
IPC: F04B49/10
Filed: 1998-12-11
Abstract: 정전시(停電時)에 있어서의 압축기의 역전현상을 확실하게 할 수 있도록 하는 것을 과제로 한다. 
     그 해결수단으로서, 압축기(16)의 운전을 제어하는 제어장치(13)과 압축기에로의 전원을 공급하는 전원변환장치(32)를 가지며, 제어장치가 리세트신호β의 입력에 의해 리세트하여 압축기를 정지시키는 공기조화장치(10)의 압축기 제어시스템(30 )에 있어서, 전원부의 전원상태를 감시하며 전원부의 전원차단시에 제어장치로 리세트신호를 출력하는 전원감시장치(33)을 구비한 것이다.
Patent KR-20000041993-A (KR)
Title: Polycarbonate-based thermoplastic resin composition having flame retardancy and excellent impact resistance
Inventor: YANG SAM JU
IPC: C08L5/00
Filed: 1998-12-24
Abstract: PURPOSE: A polycarbonate-based thermoplastic resin composition having flame retardancy and excellent impact resistance is provided which by using talc having apparent specific gravity of 0.4 - 0.6 g/c.c and particle size of 2.0 - 3.0micrometer, has excellent impact resistance and anti-drop property, and minimize the deterioration of impact strength. CONSTITUTION: A polycarbonate-based thermoplastic resin composition having flame retardancy and excellent impact resistance comprises with respect to 100 % by weight of a base resin consisting of (A) 45 - 95 % by weight of a thermoplastic polycarbonate resin containing no halogen, (B) 5 - 50 % by weight of a grafted copolymer resin having a rubber-modified styrene containing no halogen and (C) 0 - 30 % by weight of a copolymer resin having styrene containing no halogen, (D) 1 - 20 % by weight of talc having apparent specific gravity of 0.4 - 0.6 g/c.c and particle size of 2.0 - 3.0micrometer, (E) 2 - 20 % by weight of a phosphate ester compound, and (F) 0 - 2 % by weight of a fluorinated polyolefin-based resin.
Patent KR-19990063409-A (KR)
Title: 열처리장치
IPC: C23C16/40
Filed: 1998-12-24
Abstract: 반도체웨이퍼의 표면에, 예를들면 질화막과 산화막을 동일한 장치로서 연속 형성하여, 다층절연막구조를 형성할 수 있는 열처리장치이다. 배기로에 상류측으로부터 순서대로 디스크트랩(5), 밸브(MV) 및 수냉트랩(6)을 배치하고, 또 수냉트랩(6)보다 상류측의 배기관(41), 밸브(MV) 및 디스크트랩(5)을 가열하는 히터(44,51)를 설치하여, 수냉트랩(6)보다 상류측의 배기관(41), 밸브(MV) 및 디스크트랩(5)을 가열함과 동시에, 수냉트랩(6)을 냉각하여 부생성물인 NH 4 Cl을 수냉트랩(6)에서 포집하면서 Si 3 N 4 막을 형성한다. 한편 디스크트랩(5)보다 상류측의 배기관(41)을 가열하여 부생성물인 CxHy를 디스크트랩(5)에서 포집하면서 SiO 2 막을 형성한다. 웨이퍼반출시에는 밸브(MV)를 닫고, 수냉트랩(6)으로부터 NH 4 Cl이 역류하여 파티클로 되는 것을 막는다.
Patent KR-20000043359-A (KR)
Title: Preparation method of wood substitute material using mixed waste synthetic resin and apparatus thereof
Inventor: BEAK DAE HYUN
IPC: B29B17/00
Filed: 1998-12-24
Abstract: PURPOSE: Provided are a method and an apparatus for preparing a wood substitute material which is economic and has an improved durability by using a mixed waste synthetic resin. CONSTITUTION: A method comprises the steps of selecting, separating, pulverizing, washing, drying and heating a waste synthetic resin; keeping the waste synthetic resin in the accumulator at a constant temperature; and charging a mold with the waste synthetic resin; and cooling it and maintaining the shape of product under vacuum. The molding is carried out at the temperature of 210-250°C, and 1.0-1.2 wt.% of epoxy mold as a modifying agent and 0.5-0.8 wt.% of azodicarbonamide as an inorganic foaming agent are also added to the mixture to form fine pores in the center of the molded body, thereby to endow the wood substitute material with a lightness and an impact-resistance.
Patent KR-20000045002-A (KR)
Title: Phrase dictionary implementing device and its method, and phrase dictionary search method
Inventor: KIM JIN YOUNG
IPC: G06F17/30
Filed: 1998-12-30
Abstract: PURPOSE: A phrase dictionary implementing device is provided to present phrases by rows of code book index, and to make a user search phrases in the dictionary. CONSTITUTION: A phrase dictionary implementing device presents phrases by rows of code book index by vector quantizing of normalized phrases in Korea Text-to-Speech System. And to search the phrase dictionary, sentence structural and phonemic information are coded and are included in the dictionary. A user can search phrases by using the distance function of the phrase dictionary.
Patent KR-20000045737-A (KR)
Title: Synchromesh tool for manual transmission of vehicle
Inventor: KIM JONG SU
IPC: F16H3/12
Filed: 1998-12-30
Abstract: PURPOSE: A synchromesh tool for a manual transmission of a vehicle is provided to synchronize a gear butted by a clutch operation in a manual transmission of synchronous gearing type. CONSTITUTION: A shift fork gears a sleeve(6) toward a shifting gear combined a synchronizer cone(8) by operating a shifting lever and a protruded portion(6a) of the sleeve(6) compresses a ring-shaped spring(9) toward a synchronizer ring(7). A synchronous operation is started by pushing the ring-shaped spring(9) to the synchronizer ring(7) and pushing the synchronizer ring(7) toward a taper of the synchronizer cone(8). When the sleeve is returned toward a synchronizer hub(3) by withdrawing from the shifting gear, a force added to the synchronizer ring(7) is removed by returning the ring-shaped spring(9) with the elasticity. Thereby the synchronous operation is finished by withdrawing the synchronizer ring(7) from the synchronizer cone(8).
Patent KR-20000046048-A (KR)
Title: Method for announcing message reception and calling automatically in post-office box service of mobile communication system
Inventor: MIN HYONG SEOK
IPC: H04B7/26
Filed: 1998-12-31
Abstract: PURPOSE: A method for announcing message reception and calling automatically in the post-office box service of the mobile communication system is provide to call the telephone number of an originator automatically and to announce the originator whether a receiver confirms a storage message, when the receiver confirms his personal post-office box. CONSTITUTION: If a control unit inputs the calling message of a receiver outputted from a mobile switching center(310), the control unit outputs a post-office box information service message to the mobile switching center(315). The control unit inspects whether a control message by a keypad input of the receiver is a post-office box management service approach(320). If the control message is not the post-office box management service approach, the control unit carries out an associated function(325). If the control message is the post-office box management service approach, the control unit inspects whether the control message is the confirmation of a stored message(330). If the control message is not the confirmation of the stored message, the control unit carries out an associated function(335). If the control message is the confirmation of the stored message, the control unit, the control unit outputs a message stored in the personal post-office box of the receiver to the mobile switching center(340).
Patent KR-19990067163-A (KR)
Title: 레이저 이온화 질량 분석 장치 및 질량 분석 방법
IPC: H01J49/04
Filed: 1997-08-29
Abstract: 본 발명은 분자 제트를 형성하는 펄스 밸브를 구비한 시료 도입부(1)와, 펄스 레이저 빔 발진기(2)와, 해당 레이저 빔에 의해서 이온화된 분자의 질량을 분석하는 질량 분석계(4)를 가지며, 상기 펄스 레이저 발진기가 피크 출력 1MW 이상의 초단 펄스 레이저 빔을 발진할 수 있는 질량 분석 장치, 진공 이온화실(3)이 터보 분자 펌프에 의해 배기되는 질량 분석 장치, 상기 시료 도입부의 노즐(12)이 2 이상의 핀홀 노즐로 이루어지는 질량 분석 장치를 제공한다.  본 발명의 장치는 고감도이면서 동시에 고정밀도이며, 콤팩트하게 할 수 있기 때문에 연소 배기 가스 등의 신속한 분석에 위력을 발휘한다.
Patent KR-19990087711-A (KR)
Title: 방사선경화성조성물의중합에사용하기위한수성산소배리어조성물
IPC: C08L89/00
Filed: 1997-03-03
Abstract: 본 발명은 산-취약성 기판에 매립된 방사선 경화성 조성물에 사용될 때조차도 산-취약성 기판(예를 들어, 강철)의 질을 저하시키지 않는, 방사선 경화성 조성물의 중합에 사용하기 위한 수성 산소 배리어 조성물을 개시한다.  이 조성물은 (a) 수용성 산소 배리어 중합체, (b) 수용성 환원제, 및 (c) 계면활성제를 포함한다.
Patent KR-20000050510-A (KR)
Inventor: JEONG YANG HUN
IPC: H03H9/30
Filed: 1999-01-11
Abstract: PURPOSE: A synthetic filtering apparatus is provided to reduce the execution time and the space for hardware by incorporating the IMDCT calculation and the window filtering calculation into one. CONSTITUTION: An address generator(31) outputs a mode switch signal of controlling a synthetic filtering apparatus to be operated in an IMDCT mode and in a window mode and a control signal of controlling the parallel processing of data. An input data storage(32) stores inverse quantized data. A cosine table storage(33) stores a cosine table for the IMDCT calculation. A filter coefficient table storage(34) stores a filter coefficient table for the windowing calculation. A first multiplexer(38) multiplexes data of the input data storage(32) and the cosine table storage(33).
Patent KR-19990046255-A (KR)
Title: 경음기
IPC: B60Q5/00
Filed: 1999-01-15
Abstract: 본 발명은  밀폐력을  향상시켜   방수  능력을  향상시키는  경음기에 관한 것으로서,  코일이 감긴 코어에  단속적으로  전류를  공급하여  코어를 전자석으로  만들어  코어에   생성되는  자력으로  다이아프램과  일체로  형성되는  아마추어를  단속적으로  당김으로써  다이아프램을  진동시켜   경보음을 내고,  상기 코어를  수용하는  보디내에  상기 다이아프램의  진동에  따른 압력의   변화에  따라  공기가  출입할  수  있는  드레인을  형성하는  경음기에  있어서,  상기 드레인에  방수 필터를  부착하는  것을  특징으로  한다.    또한   코일이 감긴 코어에   단속적으로 전류를   공급하여   코어를 전자석으로  만들어  코어에 생성되는  자력으로  다이아프램과  일체로  형성되는  아마추어를  단속적으로  당김으로써  다이아프램을  진동시켜  경보음을 내며,  상기 코어의  하부에 나사를  형성하고  이 나사 부분을  상기 코어를  수용하는  보디내에 구멍을  형성하여  보디  외부로  돌출시켜  이를  회전시킴으로써  코어와  아마추어  사이의  간극을  조정하여  음색(音色)을  조절하는   경음기에 있어서,  상기 코어의   나사부분에   실록(seal loc)을  형성하는  것을  특징으로 한다.    또한  상기 다이아프램과 상기 보디의   결합은,  보디의   테두리에 여유를  두고  이를  말아  올려  다이아프램을  밀착,  고정시킴으로써  이루어지는  것을  특징으로  한다.
Patent KR-20000051245-A (KR)
Inventor: KIM JONG HAN
IPC: B25J13/04
Filed: 1999-01-20
Abstract: PURPOSE: An omni-directional mobile robot having the lower part of two wheels mobile robot mechanism is provided which uses only three driving gear for moving a robot to omni-direction. CONSTITUTION: An omni-directional mobile robot having the lower part of two wheels mobile robot mechanism comprises : the upper part(70) to include a case of upper part(90) forming a central treatment device, a memorial device, a switch, and a motor for connector for driving of circular type surface(50) for driving a robot ; a connector of circular type surface(60) connected with the upper part(70) by a connecting terminal(100) and revolved on a rotary axis(15) by a motor(50) ; the lower part(80) to include a case of lower part(25) forming a right and a left wheels(10, 20) equipped on the both side of the base(5), and driving motors(30, 40) driving a right and a left wheels(10, 20).
Patent KR-20000055885-A (KR)
Inventor: HA SEUNG WOON
IPC: F24F3/00
Filed: 1999-02-10
Abstract: PURPOSE: An insulation and ventilation system using underground heat is provided to carry out heat insulation function with a variable heat resistance according to the change of inside and outside temperatures by forming underground walls of a building in a dual structure having an air circulation channel and connecting or disconnecting room spaces with the underground structure. CONSTITUTION: In an underground space of a building of which underground structure(1) is installed with concrete underground continuous walls(2), an insulation and ventilation system using underground heat includes insulation walls(3) mounted with a predetermined gap with the concrete underground continuous walls, heat exchange channels(4) formed between the underground continuous walls and the insulation walls, opening holes provided with dampers(6,7) and formed at upper and lower end parts of the insulation walls for communicating the heat exchange channels with room spaces, and openings provided with a damper(8) and formed at an upper end part of the heat exchange channels for communicating to ambient air, wherein the heat resistance is variable according to the change of the temperatures of the room air and the ambient air, and ventilation of room spaces is carried out by the ambient air.
Patent KR-20000060789-A (KR)
Inventor: KIM YEON GYU
IPC: H04B7/26
Filed: 1999-03-19
Abstract: PURPOSE: An information on-demand service method for a mobile communication system is provided for providing a corresponding information in real time by an information provider based on an information on-demand request of a user in a mobile communication system. CONSTITUTION: An information on-demand service is implemented based on a continuous transaction of MT, SMS, MO, and SMS. Namely, when a certain information is requested by a user, the request is implemented using MO SMS defined in IS-637. In addition, an information response of the system is implemented based on MT SMS. The user performs a common voice call, a common MT SMS and MO SMS when an information on demand is performed. Namely, the user processes an information on demand service and common SMS during a common voice communication.
Patent KR-20000060854-A (KR)
Inventor: SO YONG CHOL
IPC: B60R11/02
Filed: 1999-03-19
Abstract: PURPOSE: A hands free device of a portable telephone for a vehicle is provided to free call without using the hands by providing a speaker and a microphone when a driver uses the portable telephone during driving. CONSTITUTION: A hands free device of a portable telephone for a vehicle includes a connector(210), a microphone(220) and a jack(230) having an amplifying and charging part(231) and a speaker(232). The connector is connected to a connector hole formed in the lower portion of the portable telephone(100). The microphone is mounted on the driver's body or at a prescribed position inside the vehicle and converts and outputs the other party's audio signal received through the portable telephone connected to the connector into electric signal. The amplifying and charging part amplifies the other party's audio signal applied through the portable telephone and charges a battery of the portable telephone using a battery power source of the vehicle. The speaker outputs the other party's audio signal amplified through the amplifying and charging part.
Patent KR-19990078104-A (KR)
Title: 고정층 수소첨가 처리단계, 비등층 전환 단계 및 접촉 분해 단계를 포함하여, 중유 분류물을 전환시키는 방법
IPC: C10G65/16
Filed: 1999-03-22
Abstract: 본 발명은 원유의 대기 증류로부터 유래한 탄화수소 분류물을 전환시키는 방법에 관한 것이다. 본 발명의 방법은, (a) 상기 공급 원료를 진공하에 증류하여 진공 증류물과 진공 잔류물을 얻는 단계, (b) 상기 진공 증류물의 적어도 일부분을 수소의 존재하에, 황 함량이 감소된 액상 유출물을 얻을 수 있는 조건하에서, 1종 이상의 고정층 수소 첨가 처리 촉매를 함유하는 하나 이상의 반응기에서 처리하는 단계, (c) 상기 진공 잔류물의 적어도 일부분을 수소의 존재하에 1종 이상의 비등층 수소 첨가 처리 촉매를 함유하는 3상 반응기에서 처리하는 단계, (d) 상기 단계 (b)로부터 얻은 생성물의 적어도 일부분을 대기 증류 영역으로 공급하여, 대기 증류 영역으로부터 경질 분류물과 중질 액상 분류물을 회수하는 단계, (e) 상기 단계 (c)에서 얻은 생성물의 적어도 일부분을 대기 증류 영역으로 공급하여, 대기 증류 영역으로부터 경질 분류물과 중질 액상 분류물을 회수하는 단계, 그리고 임의로 (f) 상기 단계 (d)와 (e)에서 얻은 중질 액상 분류물의 적어도 일부분을 적어도 부분적으로 연료 유형의 경질 분류물로 분해시키는 접촉 분해 단계를 포함한다.
Patent KR-20000061310-A (KR)
Inventor: HAN MAN HO
IPC: H04L12/28
Filed: 1999-03-25
Abstract: PURPOSE: A method for processing surplus dummy data of an IPC between a switch system and a network managing center is provided for decreasing surplus dummy data when processing control data and a character of an instruction for performing IPC communication using an EXIP between a switch system and a network management center. CONSTITUTION: When inputting a MMC instruction from a RCRT(30) by connecting a RCRT(30) of a network management center and a MMC(10) of a switch, the EXIP(20) transmits an instruction to the MMS(10) of the switch using one IPC signal in a string form until an instruction is completed in an application(AP) of a master board. An input completion of one instruction represents that an enter key is inputted from the RCRT.
Patent KR-20000061337-A (KR)
Inventor: SHIN HYEON DONG
IPC: H01L21/76
Filed: 1999-03-25
Abstract: PURPOSE: A method for manufacturing a shallow trench for isolating a semiconductor device is provided to reduce processes for the semiconductor device by simultaneously forming a liner oxide film and a pad oxide film in order to improve the productivity and the reliance. CONSTITUTION: A mask pattern for forming a trench is formed on an upper portion of a silicon wafer(11). Then, the silicon wafer(11) is etched so as to form a shallow trench. An oxide film(13) is formed on an inner wall of the trench and the surface of the silicon wafer(11). A nitride film(14) is formed on thereon. Then, the trench is filled by depositing an insulation film(15) on the nitride film(14). Then, an annealing process is carried out. The insulation film(15) is patterned such that the insulation film(15) is remained in the trench area. Then, the patterned insulation film(15) is flattened by a chemical and mechanical polishing. The nitride film(14) is then removed from the silicon wafer(11).
Patent KR-20000065660-A (KR)
Inventor: KIM KYUNG HWA
IPC: B30B9/32
Filed: 1999-04-07
Abstract: PURPOSE: A can compressor is provided to be easily used by compressing a can with a large compressive force, to prevent a damage by reinforcing a fixing pin, to easily send the can to a can input port and to keep a compact structure by installing a main body in a housing. CONSTITUTION: An empty metal can(40) is put in an input port and inserted in the input port along a can guide(32). The can is fixed between a fixing plate(36) and a compressing plate(32). Thereafter, a rotational drive force is generated by rotating a rear end of a compression lever(24) toward a front part around a shaft(34). A drive gear(30) rotates counterclockwise. A rack gear(31) moves downward and then moves the compressing plate. A drive force is removed by returning the rear end of the compression lever to an original position. The compression plate is moved upward by a return spring(33). The compressed can is discharged to a discharge hole(37) and entered in a collection case(42).
Patent KR-19990078555-A (KR)
Filed: 1999-04-19
Abstract: 1:쏘세지.어묵.가래떡.과자.모양 물품을 제조하는 식품가공 
     2: 기존 제품에 단순획일성을 개선 물품을 다물질로 합성 복합성형해 맞모양 요리방법다양성으로 식품산업발전에 기여, 
     3: 기존제조 방식, 모형성형성숙 통로를 연장하여, 연장부분에 이중으로 물질 성형관로를 장착하여 동시에,2개물질이 합성 성형되며 통로맨 끝부분에 금형조각모양(넛드식)을 장착,탈착하여,용도필요에 따라,문형을 바꾸며.제품성숙과정.냉각수조 통과때 2중물질 투입구에 0℃ ~ -3℃ 냉각수 주입시 제품 중심부가 연속천공되 제품제조 전후 양념을투입 기존제조기에,용접 간단히 장착함 
     4: 식품에 질적향상을 도모하여 맞모양 광범위한 식품문화에호응하여 식품산업발전에기여하며 조리양념절약의 효과.
Patent KR-20000073889-A (KR)
Title: Radial tire
Inventor: KIM GYUN OK
IPC: B60C3/00
Filed: 1999-05-15
Abstract: PURPOSE: A radial tire is provided to improve the durability and grounding shape of a tire belt by reducing whole end part transformed value and the difference of whole end part transformed values in case of pneumatic and loading. CONSTITUTION: In a radial tire, a radius of curvature by a carcass(1) and a belt layer(2) in a crown center region(O) is formed so that a radius of curvature of a tread part(3) is opposite to a center position of the radius of curvature of the tread part, the width of th belt layer is within 50 to 70 % range of SW(Section Width) of a tire, and the radius of curvature of the tread part is within 300 to 600 % range of the SW.
Patent KR-20010000998-A (KR)
Inventor: CHOI HYEON JONG
IPC: H04N5/445
Filed: 1999-06-01
Abstract: PURPOSE: A digital TV receiving device and a method for character/voice information of mobile phone are provided to display the character and voice information services transferred to the mobile phone on a TV screen and through a speaker. CONSTITUTION: A digital TV receiving device for character/voice information of mobile phone comprises a mobile phone mount(50), an interface(60) and a multiplexor(70). The mobile phone mount(50) comprises a battery charging electrode(50a) and a port socket(50b) and is mounted on a main body of a digital TV(100). The interface(60) enables the data communication between the digital TV(100) and the mobile phone(30) by connecting a port(30b) of the mobile phone to the port socket(50b). The multiplexor(70) selectively outputs digital signals demodulated in a VSB decoder(6) and the data of the mobile phone transferred through the interface(60) to a TP part(7) by the control of a system controller(18).
Patent KR-20010001236-A (KR)
Inventor: HA HYE YEONG
IPC: A01K67/027
Filed: 1999-06-02
Abstract: PURPOSE: A breast cancer-representing transformed mouse is provided, which shows formal change of tissue of mammary gland and breast cancer after a pregnancy or a birth by overexpression of membrane-type matrix metalloproteinase(MT1-MMP) in the mammary gland, which also induces metastasis of cancer to the other tissue, propagate itself well, and inwhich gene character is delivered well to descendants, so which can be used to develop medicine for cancer. CONSTITUTION: A process for the preparation of breast cancer-representing transformed mouse comprises: inserting PCR-synthesized mouse MT1-MMP cDMA to Sal I and Xho I of multiple cloning site of pMAMneo having MMTV promotor/enhancer to get a plasmid pmMT1; refining mMT1 DNA containing MMTV promotor/MT1-MMP cDMA after cutting the plasmid pmMT1 with a restriction enzyme Hind III; microinjecting the refined mMT1 DNA into fertilized eggs of mice, and transferring to a mouse duct to get 12 mice; cutting tails to extract genomic DNA, and amplifying mMT1 DNA with PCR method; processing electrophoresis to confirm presence of MT1-MMP from the DNA product.