baber/WOPTO huggingface dataset:
Patent NZ-334101-A (NZ)
Title: Neuraminic acid derivatives and use in treating viral infections
Inventor: HONDA TAKESHI
IPC: A61P31/16
Filed: 1997-08-12
Abstract: A neuraminic acid compound of formula (1) has in vivo sialidase inhibitory activity and may be used as a therapeutic agent or a preventive agent for viral infections. In formula (1): R1 represents a methyl group that may be substituted with one or more halogen atoms; R2, R3 and R4 may be the same or different and each represents a hydrogen atom or a C3-C25 aliphatic acyl group; and W represents a hydrogen atom or an ester residue, provided that the case where R1 is a methyl group and each of R2, R3, R4 and W is a hydrogen atom is excluded.
Patent NZ-334896-A (NZ)
Title: Benzo[de]isoquinoline-1,3-diones for inhibiting bacterial DNA gyrase and DNA topoisomerase
Inventor: AMEGADZIE ALBERT KUDZOI
IPC: A61K31/473
Filed: 1997-10-31
Abstract: A compound of Formula I or a pharmaceutically acceptable salt thereof wherein; R is hydrogen, R1-R5 are independently chosen from H, Cl, Br, F, a heterocycle or bridged heterocycle of 4-9 atoms containing 1-3 heteroatoms, NO2, OCH3, CH3 and any two of R1-R5 may form a substituted or unsubstituted ring of 5-7 total atoms having 0-2 heteroatoms; with the proviso that at least one of R1-R5 are taken together with the atoms to which they are attached to form a fused heterocycle, n is 0-5, m is 0-3, R6 and R7 are independently hydrogen, a straight or branched alkyl of 1-6 carbons, a cycloalkyl of 3-6 carbons, a heterocycle of 5-6 atoms with 1-3 heteroatoms, or Ph, all of which may be optionally substituted, R8 is a cycloalkyl of 3-7 carbons or a heterocycle of 4-9 atoms with 1-4 heteroatoms, R' is R6, F, Br, Cl, OR6, N(R6)2, and any two R's may form a ring of 3-6 total atoms with 0-2 heteroatoms, wherein the alkyls, cycloalkyls, heterocycles and Ph may be optionally substituted. The abovementioned compounds are useful in treating bacterial infections and also in selectively inhibiting bacterial DNA gyrase and DNA topoisomerase.
Patent NZ-505554-A (NZ)
Title: 8-substituted alpha or beta L guanosine analogs and derivatives useful for modulating Th1 and Th2 activities in a patient
Inventor: TAM ROBERT
IPC: C07H19/16
Filed: 1997-10-15
Abstract: A purine L-nucleoside derivative has the formula I wherein: R1 R2, R3, R4, R5, R2' and R3' are independently H, F, Cl, Br, I, N3, -CN, -OR', -NR'2, -SR', -NHNH2, -NHOH, CHO, COOR', CONR'2 or optionally substituted alkyl, alkenyl, alkynyl, aryl, or aralkyl; W = O, S, CH2 or Se; Z1, Z2 are independently N, C or CH; Z3, Z4, Z5 are independently -NR-, -O-, -S-, -Se-, C=O, -C=S, -S=O, -CR=CR-, -CR=N- or -N=N-; R is H, F, Cl, Br, I, N3, -CN, -OR', -NR'2, -SR', -NHNH2, -NHOH, -NO2, CHO, COOR', CONH2, -C(O)-NH2, -C(S)-NH2, -C(NH)-NH2, -C(NOH)-NH2 or substituted alkyl, alkenyl, alkynyl, aryl or aralkyl, the chemical bond between Z3 and Z4 or Z4 and Z5 is C-C, C=C, C-N, C=N, N-N, N=N, C-S or N-S; X and Y are independently H, F, Cl, Br, I, N3, -S-NH2, -S(O)-NH2, -S(O)2-NH2, -CN, -COOR', -CONR'2, -OR', -NR'2, -SR', NHNH2, -NHOH or optionally substituted alkyl, alkenyl, alkynyl, aryl, or aralkyl provided that i) when W is O, R1 and R4 are H, R2, R3 and R5 is OH then Z1, Z2 and Z5 is not N, Z2 is not S, Z4 is not CO, Y is not NH2 and X is not OH; ii) when R2 and R3 are OH then X is not NH2; iii) when X is halo, NH2, H, OH or SH and /or Y is halo, NH2, H, OH or SH, then R2 and/or R3 are not H; iv) when Y is NH2 then Z3 is not O or S and v) when W is S at least one of R2, R2', R3 and R3' must be OH. A pharmaceutical composition thereof is useful for treating infections, infestations, neoplasm, or autoimmune diseases or for modulating Th1 and Th2 activities in a patient.
Patent NZ-508403-A (NZ)
Title: Process for producing simvastatin and intermediates produced via this process.
Inventor: MURTHY K S KESHAVA
IPC: C07F5/02
Filed: 1997-09-05
Abstract: A method for the preparation of simvastatin from lovastatin.  Various reaction intermediates are also described.
Patent NZ-510926-A (NZ)
Title: Tissue web softening compositions including an electrolyte and a bilayer disrupter to reduce it's viscosity
Inventor: VINSON KENNETH DOUGLAS
IPC: C11D1/74
Filed: 1999-10-08
Abstract: Disclosed is a composition for softening an absorbent tissue and tissue structures softened using the composition.  The composition includes an effective amount of a softening active ingredient; a vehicle in which the softening active ingredient is dispersed; an electrolyte dissolved in the vehicle; and a bilayer disrupter.  The electrolyte and the bilayer disrupter cooperate to cause the viscosity of the composition to be less than the viscosity of a dispersion of the softening active ingredient in the vehicle alone.  Preferably, the softening active ingredient is a quaternary ammonium compound with the general formula: (R1)4-m - N4 - [(CH2)n - Y - R3]m X-; the vehicle is water, the electrolyte is calcium chloride, and the bilayer disrupter is a nonionic surfactant.
Patent NZ-517598-A (NZ)
Title: Improved pumping apparatus and methods
Inventor: ZAHER MOUAFAK ARIF
IPC: F04D29/66
Filed: 1998-03-13
Abstract: Fluid is bled from a pump outlet pipe (at 2) back to the pump inlet via lines 1 (only one shown).  Bleed flows are injected at higher velocity heads (at 3) compared to bleed outlets (at 2).  The injecting means comprises a circular cross sectional passage for fluid with (a) an inlet for bleed flow to be received from the bleed means and (b) an outlet connected for bleed flow delivery to the inlet conduit, wherein the ratio of the diameter of its inlet to the diameter of its outlet is 2:1.
Patent NZ-518759-A (NZ)
Title: Hybrid matrices and hybrid matrix mixtures
Inventor: MINEAU-HANSCHKE ROCHELLE
IPC: A61P17/02
Filed: 2000-10-04
Abstract: A composition comprising a body of matrix material comprising insoluble collagen fibrils, there being embedded within the body of matrix mater; (a) a first population of cultured vertebrate cells genetically engineered to express a polypeptide; (b) a plurality of microcarriers; and (c) an agent selected from the group consisting of a factor which promotes vascularization, a cytokine, a growth factor and ascorbic acid, wherein the agent is bound to a solid substrate embedded in the body of the matrix material; a method of making the composition; and the use of the composition in therapy.
Patent NZ-519430-A (NZ)
Title: Dense refractory material for use at high temperatures
Inventor: NGUYEN THINH T
IPC: C04B41/50
Filed: 2000-12-06
Abstract: A component which is made of or coated with a refractory material for use at high temperature, the refractory material comprising particles of a refractory metal compound in an oxide matrix, the refractory metal compound being selected from metal borides, silicides, nitrides, carbides and phosphides, the oxide matrix comprising a bonding mixed oxide made of a single mixed oxide or a plurality of miscible mixed oxides, the refractory material being obtainable from a heat treated slurry that comprises: a) a colloidal and/or polymeric carrier that comprises colloidal and/or polymeric oxide of at least one metal; b) suspended particles of the refractory metal compound that are covered with a film of oxide of the metal of the refractory metal compound, the oxide film being reactable upon heat treatment with said colloidal and/or polymeric oxide to form a mixed oxide comprised in said bonding mixed oxide; and c) suspended metal oxide particles which are reactable upon heat treatment with said colloidal and/or polymeric oxide to form a mixed oxide comprised in said bonding mixed oxide, wherein the bonding mixed oxide consists of: -a single mixed oxide when the metal of the suspended metal oxide particles is the same as the metal of the suspended refractory metal compound particles and the reactable oxide of said colloidal and/or polymeric oxide is an oxide of one metal only; or -a plurality of miscible mixed oxides when at least one metal of the suspended metal oxide particles is different to the metal of the suspended refractory metal compound particles and/or when said colloidal and/or polymeric oxide comprises reactable oxides of different metals.
Patent NZ-526085-A (NZ)
Title: Substituted imidazopyridines
Inventor: LINDSTROM KYLE JON
IPC: A61P43/00
Filed: 2001-12-06
Abstract: Disclosed are compounds of formula (I), wherein: X is alkylene or alkenylene, Y is -CO-, -CS-, or -SO2-, Z is a bond, -O-, -S-, or -NR5-, R1 is optionally substituted aryl, heteroaryl, heterocyclyl, alkyl or alkenyl, R2 is H, alkyl, alkenyl, -alkyl-O-alkyl, -alkyl-S-alkyl, -alkyl-O-aryl, -alkyl-S-aryl, -alkyl-O-alkenyl, -alkyl-S-alkenyl, or optionally substituted alkyl or alkenyl, R3 and R4 are independently alkyl, alkenyl, halogen, alkoxy, amino, alkylamino, dialklyamino or alkylthio, each R5 is H or alkyl. The compounds are used in the manufacture of medicaments for inducing cytokine biosynthesis in animals, the treatment of viral diseases or neoplastic diseases.
Patent NZ-527208-A (NZ)
Title: Concatemers of differentially expressed multiple genes
Inventor: GOLDSMITH NEIL
IPC: C12N1/15
Filed: 2002-01-25
Abstract: Concatemers of concatenated expression cassettes and vectors that enable the synthesis of such concatemers are disclosed. The main purpose of these concatemers is the controllable and co-ordinated expression of large numbers of heterologous genes in a single host. Furthermore, described are concatemers of cassettes of nucleotide sequences and a method for preparing the concatemers. In a further aspect, transgenic host cells comprising at least one concatemer are described, as well as to a method for preparing the transgenic host cells. Finally, a vector is described comprising a cassette of nucleotides, a method for preparing the vector, a nucleotide library comprising at least two primary vectors each comprising a cassette of nucleotides, and a method for preparing the library.
Patent NZ-528526-A (NZ)
Title: Manifold with swivel input port for monobloc lead-acid battery single point watering system
IPC: H01M50/627
Filed: 2003-09-29
Abstract: A single point watering system for refilling individual cells of a multi cell monobloc lead-acid battery wherein each battery cell is fitted with a refill connector fitting. The manifold has a plurality of outlet bosses positioned at a predetermined spacing to permit the manifold to be assembled to the battery with each outlet boss in sealed fluid communication with one of the refill control valves, at fitting, and a longitudinally extending passageway for fluid swivel connector fitting has an outlet boss. The swivel connector fitting has an outlet boss which is mounted within the manifold inlet port in sealed fluid communication and is rotatable within the inlet port through 360 degree . The swivel connector fitting also includes ports to communicate with other components of the single point watering system.
Patent NZ-532184-A (NZ)
Title: Intraorally disintegrating valdecoxib compositions in which the excipient - a saccharide - is present in intimate association in an amount between 50% and 90%
Inventor: REO JOSEPH P
IPC: A61P25/28
Filed: 2002-10-10
Abstract: Orally disintegrating valdecoxib fast-melt tablets and processes for preparing such dosage forms are provided. The compositions are useful in treatment or prophylaxis of cyclooxygenase-2 mediated conditions and disorders.
Patent NZ-537401-A (NZ)
Title: Proteases from Aspergillus niger
Inventor: EDENS LUPPO
IPC: A23L33/00
Filed: 2002-02-22
Abstract: A tripeptidyl peptidase (EC.3.4.14.9) is encoded by a polynucleotide being at least 60% homologous to the sequence of SEQ ID NO:10 or 67, preferably the peptidase has the amino acid sequence of SEQ ID NO:124. Polypeptides, vector, methods of manufacturing, antibodies and recombinant host cells are described. The nucleotides or antibodies can be used in diagnosing whether an organism is infected with Aspergillus.
Patent NZ-541176-A (NZ)
Title: Shipping container sealing assembly apparatus and method using security wire and RFID tag
Inventor: WALKER STEVE
Filed: 2005-07-08
Abstract: A container sealing assembly (100) for impeding tampering of a shipping container (200) is disclosed. The shipping container (200) has a first door (202), lockable in a closed position by a first locking bar (208B), and a second door (204), lockable in a closed position by a second locking bar (208C). The container sealing assembly comprises: (a) a housing; (b) an RFID tag assembly at least partially disposed within the housing; (c) an electrically conductive element (114) adapted to be locked to the housing, where the electrically conductive element (114) is dimensioned to encircle simultaneously the first and second locking bars (208B, 208C); and (d) wherein the RFID tag assembly is adapted to detect conductivity of the electrically conductive element (114) and transmit a code remotely of the container sealing assembly indicating tampering if a break in conductivity is detected.
Patent NZ-541683-A (NZ)
Title: Vehicle parking monitoring apparatus, system and method
Inventor: COLLINS PAUL MAXWELL
Filed: 2005-11-05
Abstract: A vehicle metering device (2) for detecting and metering a vehicle parked on a parking space or bay is disclosed. The device (2) has components including a control means (4), vehicle sensing means (3), a power supply means (9) to power the components of the device, and a telecommunication means (5) configured and arranged together in a durable casing. The vehicle sensing means (3), in use, is mounted in or about a parking space to detect when a vehicle parks and when it leaves the parking space. It also feeds status signals to the control means (4), where the control means (4) includes a timer means for counting out a preset time period representing an allowable time period for which a vehicle can be legally parked. The control means (4) is programmed, in use, to generate and send an output coded signal via the telecommunication means (5) to a remote receiver means to confirm the time period that a vehicle in the parking space has been parked, along with identification of the parking space.
Patent NZ-543889-A (NZ)
Title: Multi-ingredient stock cube for preparation of liquid foods or food component
Inventor: LENOBLE HENRI-PIERRE
Filed: 2002-02-08
Abstract: A stock article for the preparation of liquid foods or food ingredients is disclosed. The stock article has a shaped, dimensionally stable body of at least two sections (1'', 2'') comprising solid stock mixes or loose stock mixtures. The stock mixes or mixtures in different sections have different food colourings. The shaped body is enclosed by paper-like or film-like packaging material (3). (62) (62) Divided out of 527982
Patent NZ-545457-A (NZ)
Title: Electric security fence system
Inventor: PARKER STUART ROY
Filed: 2006-02-20
Abstract: An electric fence system is disclosed. The electric fence system includes at least two fencing assemblies (2) for fitting to the top of a supporting fence (1), where each of the fencing assemblies (2) include at least two electrically conductive palings (3) configured to form part of an electric fence system and at least one conductive rail (4) configured to connect at least two conductive palings (3). The electric fence system also includes an insulative connector configured to attach to a support post of the supporting fence and locate a conductive engaging member to electrically connect at least two fencing assemblies (2), such that the fencing assemblies are electrically isolated from the supporting fence (1).
Patent NZ-548042-A (NZ)
Title: Fluorometers
Inventor: AASMUL SOREN
IPC: G01N21/64
Filed: 2004-12-20
Abstract: In apparatus for the production and detection of fluorescence at a sample surface, the height of the apparatus above the sample surface is reduced, and loss of the emitted fluorescence due to reflection loss and light scattering is minimized. The apparatus comprises a three-dimensionally curved light reflecting surface (40) that directs light from a light source (32) transversely to its original path and focuses the light on to an illumination zone (30) at or below the sample surface. The reflecting surface (40) also collects, directs and at least partially collimates emitted fluorescence transversely to its original path and towards a detector (46).
Patent NZ-548685-A (NZ)
Title: Reduction of spontaneous mutation rates in cells
Inventor: STROBEL HEIKE
IPC: C12N15/09
Filed: 2005-02-26
Abstract: Provided is a process for making a cell having a reduced spontaneous mutation frequency comprising; a) introducing an antimutator allele of a gene encoding DNA polymerase IV and an antimutator allele of a gene encoding a sub-unit of DNA polymerase III; or b) introducing an antimutator allele of a gene encoding DNA polymerase IV or an antimutator allele of a gene encoding a sub-unit of DNA polymerase III, and overexpressing Mutl or MutS; or c) introducing an antimutator allele of a gene encoding DNA polymerase IV and an antimutator allele of a gene encoding a sub-unit of DNA polymerase III, and overexpressing Mutl or MutS; or d) introducing an antimutator allele of a gene encoding DNA polymerase IV and an antimutator allele of a gene encoding a sub-unit of DNA polymerase III, 15 and over-expressing Mutl and MutS. Further provided are cells obtained by the said process and use of such cells for the production of proteins and fermentation products.
Patent NZ-549681-A (NZ)
Title: Paper machine belt conditioning system, apparatus and method
Inventor: RIVARD JAMES P
IPC: D21F1/00
Filed: 2005-01-31
Abstract: A belt cleaning apparatus 10 for a continuous belt 50 with a water impermeable surface, comprises a face side roll 58 that contacts the water impermeable surface of the belt 50 and a chemical spray 70 placed next to the face side roll 58, where the chemical spray 70 can be operated to spray a conditioning chemical on the water impermeable surface of the continuous belt 50 or on the face side roll 58. This arrangement helps the machine of which the belt is part, operate faster.
Patent NZ-551441-A (NZ)
Title: Refuse processing method using quick lime
Inventor: MARTIN ERIC
IPC: B03B9/06
Filed: 2005-03-09
Abstract: Disclosed is a method of processing refuse including organic and non-organic materials, wherein the method comprises the steps of: A) admixing quicklime and a highly slaked substance with said refuse, B) allowing said organic materials to react to give a product that includes a calcium organic complex and said non-organic materials, and C) separating said non-organic materials from said calcium organic complex.
Patent NZ-552034-A (NZ)
Title: Microfluidic device and leucocyte antigen mediated microfluidic assay
Inventor: RODRIGUEZ R
IPC: G01N33/53
Filed: 2005-05-13
Abstract: Provided is a leucocyte antigen mediated microfluidic assay for testing a leucocyte containing fluid from a subject for prior exposure to a predetermined antigen which would have caused the leucocyte to become presensitized to the antigen comprising: performing a first test comprising the steps of: a) placing a microvolume first sample of the subjects leucocyte containing fluid in a first sample microchamber; b) transporting the first sample to a first reaction microchamber containing the predetermined antigen and an antigen accelerator and allowing them to react together for a predetermined time; c) transporting the reacted first sample to a first observation microchamber; d) mixing one or more leucocyte observation colorants with the reacted first sample during transportation to the observation microchamber or in the observation microchamber; e) optically performing an optical scan of the reacted sample in the first observation microchamber under conditions which allow the measurement of at least 1 measurement factor of the leucocytes in the reacted first sample; performing a second test comprising the steps of: a) placing a microvolume second sample of the subjects leucocyte containing fluid in a second sample microchamber; b) transporting the second sample to an antigen free second reaction microchamber containing the same antigen accelerator as the first test and allowing them to react for the predetermined time; c) transporting the second sample to a second observation microchamber; d) mixing the same leucocyte observation colorants as the first test with the reacted second sample during transport to the second observation microchamber or in the second observation microchamber; e) optically performing an optical scan of the reacted second sample in the second observation microchamber under conditions that allow the measurement of the same leucocyte measurement factors measured in the first test; comparing the results of the first test scan to the second test scan to determine if any differences between the two scans are due to a leucocyte-antigen mediated response wherein the optical scan is accomplished by multi-wavelength fluorescence image analysis. Also provided is a corresponding device for the assay.
Patent NZ-552602-A (NZ)
Title: Hydrophilic polymers and their use as membranes in electrochemical cells
Inventor: HIGHGATE DONALD JAMES
IPC: C25B9/23
Filed: 2002-09-09
Abstract: Disclosed is a hydrophilic polymer obtainable by copolymerisation of hydrophobic and hydrophilic monomers that give a hydrophilic polymer on polymerisation wherein the copolymerisation is conducted in the presence of water and a monomer including a strongly ionic group. The hydrophilic polymer may be cross-linked; the monomers may include a separate cross-linking agent; and the polymerisation comprises gamma-irradiation or thermal initiation. These polymers are electrically conducting and are suitable for membranes in an assembly that can be used in electrolysers and electrochemical cells, e. g. fuel cells.
Patent NZ-556602-A (NZ)
Title: A panel antenna and method of forming a panel antenna
Inventor: EHLEN MATHIAS MARTIN ERNEST
IPC: H01Q1/36
Filed: 2007-07-18
Abstract: A panel antenna comprises a panel formed of dielectric material; a plurality of radiating elements formed on a surface of the dielectric material by forming grooves in a first conductive sheet secured to the dielectric material; and a feed network for the radiating elements formed by forming grooves in the first conductive sheet. A method of forming the antenna is also disclosed.
Patent NZ-564581-A (NZ)
Title: Device for the withdrawal, collection and transport of biological specimens with cap of pierceable but impermeable material
Inventor: TRIVA DANIELE
IPC: C12M1/30
Filed: 2006-05-02
Abstract: The disclosure relates to a device for the withdrawal, collection and transport of biological specimens, comprising a test tube equipped with a cap comprising a membrane constructed of a soft material impermeable to liquids and pierceable by a suitable specimen withdrawal means.
Patent NZ-566362-A (NZ)
Title: Intercalated layered silicate
Inventor: GRAH MICHAEL D
IPC: C01B33/44
Filed: 2006-08-15
Abstract: Disclosed is an intercalated layered silicate comprising: a layered silicate comprising a plurality of silicate layers; and an intercalating agent sorbed between the silicate layers in an amount effective to provide an average interlayer spacing between the silicate layers of at least about 20Å, wherein the intercalating agent is selected from one or more of ethoxylated fatty esters of sorbitan and fatty acid esters of polyglycerol. Also disclosed is a method of exfoliating a layered silicate comprising: mixing from about 0.1 to about 100 weight parts of the intercalated layered silicate of anyone of the preceding claims with 100 weight parts of a matrix medium to form a mixture; and adding sufficient energy to the mixture to form a dispersed-particle composition comprising at least about 0.1 weight parts exfoliated particles per 100 weight parts matrix medium. Also disclosed is the use of the layered silicate for packaging food.