baber/WOPTO huggingface dataset:
Patent CA-2453406-A1 (CA)
Title: Methods for reducing immunogenicity of polypeptides
Inventor: CARR FRANCIS J
IPC: A61K38/02
Filed: 2002-07-12
Abstract: This invention relates to the fields of immunology and protein therapeutics.  The therapeutic proteins are polypeptides to be administered especially to humans. The polypeptides are modified whereby the modification results in a reduced propensity for the polypeptide to elicit an immune response upon administration to the human subject. The invention therefor provides methods for the development of therapeutic polypeptides that are less immunogenic than any non-modified counterpart when used in vivo. The modifications used according to this invention relate, for example, to the introduction of protease cleavage sites, attachment of different molecules or insertion of non-natural amino acids.
Patent CA-2455062-A1 (CA)
Inventor: BERNASCONI SERGIO
IPC: A44B19/30
Filed: 2004-01-09
Abstract: A description is given of a slider (1) with two pull tabs (2, 3) arranged symmetrically with respect to each other and each provided with a ring (2a, 3a), the slider comprising a hollow body (4) containing an escapement (5), the pawl (6) of which is designed to be inserted between the teeth of the zip in order to prevent movements between the zip and the slider (1), the escapement (5) being provided with elastic means (7) which keep its pawl (6) inserted between the teeth until it is disengaged by one or other of the pull tabs (2, 3). In the slider in question one (2) of the pull tabs (2, 3) is in contact with the escapement (5) via its ring (2a) in such a way that, when operated, it produces the said disengagement, and the other pull tab (3) is positioned with its ring (3a) in contact with an inclined plane (8) of a rigid member (9) which is positioned in such a way that operating the abovementioned pull tab (3) causes a rotation of the rigid member (9) sufficient to press it against one end (20i) of a movable pin (10) and to move it axially in such a way that the other end (20s) pushes the escapement (5), overcoming the resistance of the said elastic means (7) and disengaging the pawl (6) thereof.
Patent CA-2455433-A1 (CA)
Title: Hydrophilic surface modifying macromolecules (h-phil smm) and h-phil smm blended membranes
Inventor: RANA DIPAK
IPC: C08G18/10
Filed: 2004-01-20
Abstract: The present invention provides hydrophilic surface modifying macromolecules (H-phil SMM) and H-phil SMM and blended membranes produced incorporating the hydrophilic surface modifying macromolecules.      The membranes include a hydrophilic base polymer, and the hydrophilic surface modifying macromolecules (H-phil SMM) which impart surface hydrophilic properties to the membrane. The membranes produced with the surface modifying macromolecules give polymer membranes useful in the separation of water from a solution containing volatile organic compounds and water.
Patent CA-2456128-A1 (CA)
Inventor: HEDRICK JOSEPH R
IPC: G07F17/32
Filed: 2002-07-25
Abstract: A disclosed a player tracking unit provides a display, one or more illumination devices adjacent to the display and a logic device designed to control illumination of the illumination devices in a manner that visually conveys gaming information to an individual viewing the devices. A speaker may be also provided on the player tracking unit to aurally convey gaming information such as voice messages designed to inform or instruct the player in some manner. The player tracking unit may include a wireless interface device designed or configured to allow player tracking information to be automatically downloaded from a portable wireless device carried by the player or player status information to be communicated to a casino service representative carrying a portable wireless device.
Patent CA-2456323-A1 (CA)
Inventor: JUNG MICHAEL
IPC: C07K7/64
Filed: 2002-08-06
Abstract: La présente invention concerne des composés stéréo-isomères de daptomycine, des méthodes et des intermédiaires permettant la préparation de daptomycine et de composés stéréo-isomères de daptomycine, ainsi que des compositions pharmaceutiques desdits composés et des méthodes d'utilisation desdites compositions en tant qu'agents antibactériens.
Patent CA-2457123-A1 (CA)
Title: Processes for manufacturing water filters
Inventor: ZAVERI PIYUSH NARENDRA
IPC: B01D39/20
Filed: 2002-08-23
Abstract: A process for producing a water filter material is provided. The process includes the steps of providing a plurality of carbon particles having a point of zero charge of less than about 7, wherein the sum of the mesopore and macropore volumes of the plurality of filter particles is greater than about 0.12 mL/g. The plurality of carbon particles are exposed to a converting agent and heated in a furnace after the step of exposing.
Patent CA-2457436-A1 (CA)
Inventor: BAJUSZ SANDOR
IPC: A61P31/04
Filed: 2002-08-21
Abstract: L'invention se rapporte à la coagulation intravasculaire disséminée. Plus précisément, elle a trait à une intervention médicale pour traiter la coagulation intravasculaire disséminée. Cette invention porte sur de nouveaux peptides arginaux, sur de nouveaux et meilleurs composés, et sur des méthodes de traitement de la coagulation intravasculaire disséminée (CIVD). Ces composés et ces méthodes selon l'invention possèdent une action inhibitrice sur la thrombine liée au caillot et sur le facteur Xa ; ils présentent également une action inhibitrice contre la plasmine et les activateurs du plasminogène.
Patent CA-2458674-A1 (CA)
Title: Zirconium/metal oxide fibres
Inventor: WOODHEAD JAMES L
IPC: B01J23/00
Filed: 2002-09-12
Abstract: A zirconium metal oxide fibre comprises zirconium oxide and a metal oxide. The fibre is made by adding a metal oxide in a suitable form to a colloidal dispersion of an amorphous zirconium polymer. The mixed colloidal dispersion is subsequently made into a fibre. The fibre may be used as a substitute for glass fibre in the manufacture of paper and paper-like materials. The fibre's thickness is substantially uniform and has a length usually in excess of one micron.
Patent CA-2459090-A1 (CA)
Inventor: MAIDEN JANICE R
IPC: G02B6/08
Filed: 2002-08-28
Abstract: A flexible carrier (10, 30, 40) for supporting and protecting elongated item s (16) such as optical fibers is disclosed. The carrier (10, 30, 40) is formed from a substrate (12, 24, 42) of interlaced filamentary members which may be woven, knitted or braided together. The elongated items (16) are interlaced with or otherwise captured by the substrate (12, 24, 42) during its manufacture. Various configurations of the substrate such a flat, pleated an d tubular are feasible. Capture of the elongated members may be effected by integrally woven tubes formed within the substrate, by interweaving the item s as warp yarns in a woven substrate or by laying in of the items in a knitted substrate.
Patent CA-2463276-A1 (CA)
Title: Real-time on-line sensing and control of mineral scale deposition from formation fluids
Inventor: YUAN MINGDONG
IPC: E21B47/00
Filed: 2002-02-21
Abstract: The present invention provides a method and system for controlling mineral scale deposition from a formation fluid. The rate at which scaling is occuring is measured in real time using an attenuated total reflectance probe and a photometer. The results are then used to determine whether to increase, decrease or leave unchanged addition of anti-scaling additives.
Patent CA-2463583-A1 (CA)
Title: Highly compressible ethylcellulose for tableting
Inventor: DURIG THOMAS
IPC: A61P31/04
Filed: 2002-10-08
Abstract: A pharmaceutical dosage form composition is composed of an ehtylcellulose that has an ethoxyl range lower limit of 49.6%, an a viscosity of less than 53 cps and at least one active pharmaceutical ingredient. This dosage form is highly compressible and compactible forming harder tables or pellets with better release retardation than comparable prior art tablets.
Patent CA-2463617-A1 (CA)
Inventor: ROFALL KLAUS
IPC: F04C25/02
Filed: 2002-10-30
Abstract: The invention relates to a screw-type vacuum pump (1) comprising a pump housing (2, 6) with rotors (3, 4) arranged therein, a liquid cooling system for the rotors and a drive motor (9). In order to improve the cooling of sai d pump, an external air-flow impelled cooling system is also provided for the pump housing (2,6).
Patent CA-2464609-A1 (CA)
Title: Use of egf to inhibit pathogenic infections of the urogenital tract
Inventor: GALL D GRANT
IPC: A61P31/04
Filed: 2002-10-25
Abstract: This invention relates to treating or preventing pathogenic infections with an epidermal growth factor (EGF). EGF is capable of inhibiting pathogenic colonization of pathogens in a variety of tissue or cell types. Since pathogenic colonization is essential for pathogenic infection, EGF can be us ed as an effective preventive and therapeutic agent for pathogenic infections, particularly in the urogenital tract.
Patent CA-2466661-A1 (CA)
Title: Posterior vertebral joint prosthesis
Inventor: LOUIS RENE
IPC: A61B17/58
Filed: 2002-11-15
Abstract: The invention concerns a posterior vertebral joint prosthesis. The inventive posterior left or right joint prosthesis (1, 2) has a smooth support surface (11, 11a, 11b, 17, 17a, 17b) and said surface includes an antero-posterior curvature.
Patent CA-2468254-A1 (CA)
Inventor: JAYARAMAN SWAMINATHAN
IPC: A61L29/00
Filed: 2002-11-22
Abstract: The invention relates to a coating for an intravascular implant that prevents hyperproliferative vascular disease after a mechanical injury, such as angioplasty. The coating includes first and second agents, with the first agent acting on a calcium independent cellular pathway and the second agent acting on a calcium dependent cellular pathway. In an exemplary embodiment, the first agent is rapamycin and the second agent is cyclosporine A. The agents can be incorporated in a polymeric agent and can be applied either directly to the implant or on top of a primer layer placed on the implant. A  top coat can be applied to the therapeutic coating, if desired.
Patent CA-2468521-A1 (CA)
Title: System and method utilizing dynamic beam forming for wireless communication signals
Inventor: CHITRAPU PRABHAKAR R
IPC: H04W36/00
Filed: 2002-11-26
Abstract: The present invention relates to a method and system using dynamic beam forming for wireless communication signals in a wireless network. Base stations and/or Ues are provided with antenna systems having a range of beam forming selections. Relativebase station and UE locations are one type of criteria used to make beam forming decisions.
Patent CA-2470834-A1 (CA)
Inventor: SAILER PETER
IPC: F01L1/255
Filed: 2003-01-15
Abstract: L'invention concerne un élément de commutation (1) pour un mécanisme de commande de soupapes d'un moteur à combustion interne, de préférence pour la coupure de soupapes. Selon cette invention, le jeu d'accouplement de moyens d'accouplement (8), situés dans un évidement (6), s'effectue facilement par l'intermédiaire de deux bagues de serrage (19, 20), dont une est variable en épaisseur.
Patent CA-2474259-A1 (CA)
Title: Anticorps luttant contre de nouveaux derives d'amphetamine et compositions contenant de nouveaux derives d'amphetamine
Inventor: KUSMIEREK JACQUES
IPC: A61K39/385
Filed: 2003-01-22
Abstract: La présente invention concerne des conjugués porteurs d'haptène, permettant d'obtenir des anticorps anti-haptène luttant in vivo contre des amphétamines. La présente invention concerne également des procédés pour préparer ces conjugués porteurs d'haptène et des compositions thérapeutiques. Une composition thérapeutique contenant le conjugué porteur d'haptène est utilisée pour traiter une toxicomanie aux amphétamines. Cette invention a également trait à une immunisation passive obtenue par utilisation d'anticorps luttant contre des conjugués selon la présente invention. La composition thérapeutique selon cette invention est adaptée à une co-thérapie avec d'autres médicaments classiques pour traiter un abus d'amphétamines.
Patent CA-2477015-A1 (CA)
Inventor: PENDELL BARRY JACK
IPC: A01N43/80
Filed: 2004-08-09
Abstract: The present invention relates to a process for producing emulsion of one or more water insoluble active ingredients directly before introducing them into aqueous systems. One or more water insoluble active ingredients including biocides are intimately mixed together by feeding an aqueous dispersion through a static micro-mixing device. The active ingredients are introduced into the aqueous systems as emulsions free of surfactants and having reduced to no amounts of organic solvents.
Patent CA-2483066-A1 (CA)
Inventor: HAYATA YOSHIMI
IPC: B23K11/14
Filed: 2004-09-29
Abstract: This invention is, in a vibration type parts feeding method and its device that welding nuts are put on a parts transportation track (3) arranged in an inner wall of a vibration bowl (2) of a parts feeder to be arranged in turn and normal positioned welding nuts are sorted and transported from a parts discharging outlet at a top end portion of the track to a desired place, that a sort unit (7) for passing only the normal positioned welding nuts is installed detachably to adjacent to the parts discharging outlet of the vibration bowl (2), and thus, that it becomes possible to correspond to sorting upward and downward of the welding nuts with various kinds of shapes and dimensions.
Patent CA-2484498-A1 (CA)
Inventor: ZHOU TIAN
IPC: B66B13/12
Filed: 2004-10-12
Abstract: The clutch (10) is designed for coupling a car door of an elevator car with a landing door of an elevator system, wherein the car door is movable with respect to the elevator car by means of a first actuator. The clutch (10) comprises at least one coupling element (20) and a second actuator. The coupling element is movable with respect to the car door between a first position and a second position by means of the second actuator such that the coupling element (20) engages with the landing door when the elevator car is within a landing zone and the coupling element is moved towards the second position, thereby establishing the coupling of the car door with the landing door. The second actuator is a linear motor (40).
Patent CA-2485884-A1 (CA)
Title: Method and apparatus to determine a target location in body coordinates
Inventor: JORDAN LAVELL
IPC: G01S13/935
Filed: 2003-05-13
Abstract: A method for determining a position of a doppler radar target in aircraft body coordinates is described. The method includes calculating values for doppler circle equations (620), in doppler coordinates, based upon a range to the target, a vehicle velocity, and a center frequency and bandwidth of a doppler swath filter. Further, an interferometric circle (622) in body coordinates is calculated based upon a range to the target, and an interferometric angle. The doppler circle equations are transformed into bady coordinates (624) utilizing received pitch, roll and yaw information. Finally, an intersection (626) of the interferometric circle equations with the transformed doppler circle equations is calculated, the intersection being the position of the target in body coordinates.
Patent CA-2487564-A1 (CA)
Title: Folic acid-chitosan-dna nanoparticles
Inventor: YAN CUIE
IPC: A61K31/519
Filed: 2004-11-12
Abstract: The present invention relates to a non-viral novel drug delivery system.  Nanoparticles comprising folic acid and chitosan are used to deliver a therapeutic agent of interest to the cell for various therapeutic applications.
Patent CA-2487745-A1 (CA)
Title: Multipurpose system for the automatic washing and drying of industrial containers and appliances in controlled environmental conditions
Inventor: STROPPOLO FEDERICO
IPC: B08B9/00
Filed: 2004-11-18
Abstract: The present invention relates to a multipurpose system for the automatic washing and drying of industrial containers and appliances, in controlled environmental conditions.
Patent CA-2488557-A1 (CA)
Title: Apparatus for cutting food product
Inventor: BUCKS BRENT
IPC: B26D3/28
Filed: 2003-06-04
Abstract: An apparatus (10) for cutting food product so that the product isproperly oriented and stabilized before and throughout the cutting operation to produce a sliced product of uniform thickness, even if the delivered food product varies in shape and size, such as when both round and elongate potatoes are used to produce potato chips. The apparatus (10) includes a cutting device (12) and housing thereabove that defines a passage (50, 32, 132) with an opening (44) in proximity to the cutting device (12), such that food product is delivered to the cutting device (12) in a substantially vertical direction.  To improve the stability of round product during the cutting operation, the housing has an upper portion (40, 140) and a flared lower portion (42, 142) immediately below the upper portion (40, 140) so that at least a portion of the opening (44) of the passage is defined by the flared region (56, 156) and has a larger radius of curvature than the upper portion (40, 140).
Patent CA-2488743-A1 (CA)
Title: Multi ball self-adjusting self-centering tool holder (mbssth) and multi ball self-adjusting self-centering clamping system (mbsscs)
Inventor: VEINBERG LEONID S
IPC: B23Q3/12
Filed: 2004-12-08
Abstract: The invention is a high precision tool holder and clamping system, where base centering and holding of tools is realized by using a special Multi Ball Self-adjusting Self-centering Insert (MBSSI). This insert consists of high precision balls assembled in a specific order (in staggered rows) and held together as one unit by using an elastic substance or a special separator. The balls are arranged in a position of stable equilibrium and have permanent contact with each other. Due to that, the system is statically determinate and has a very high precision. Multi Ball Self-adjusting Self-centering Insert (MBSSI) provides uniform distribution of base points on a tool surface (a-spot) with full force closure. Due to that, the Multi Ball Self-adjusting Self-centering Tool Holder (MBSSTH) and Mufti Ball Self-adjusting Self-centering Clamping System (MBSSCS) achieve very high rigidity.
Patent CA-2488955-A1 (CA)
Title: Pharmacy dispensing system and method
Inventor: SCHULTZ DAVID A
IPC: G06F17/00
Filed: 2004-12-03
Abstract: A system for filling a prescription order for a patient includes a plurality of trays each having any RFID tag for storing a unique identifier corresponding to the prescription order, and a plurality of workstations operatively linked to one another, each workstation having an antenna for detecting the unique identifier in one of the plurality of trays, where the detecting is operative to trigger displaying a profile of at least one prescription item for the corresponding prescription order.
Patent CA-2490645-A1 (CA)
Inventor: BAEK OCK KEE
IPC: G06F15/82
Filed: 2004-12-16
Abstract: A distributed computing system provides a data management system in communication with a software management system and enables the software applications to move to the data to be processed in a distributed computing environment. The software management system stores a plurality of computer-executable software applications thereon and is in communication with a user system for receiving a selection of one of the plurality of software applications. The software management system also generates an identifier for the selected software application which is provided to the data management system. The data management system obtains the selected software application from the software management system based on the identifier. The obtained software application is then executed with data from a data storage system using resources from a resource system. The resource system comprises a plurality of resources and a manage mechanism for managing assignment of the plurality of resources to support execution of the software application.
Patent CA-2491558-A1 (CA)
Title: Acoustic transducers for tubulars
Inventor: MASSON JEAN-PIERRE
IPC: E21B47/01
Filed: 2005-01-05
Abstract: Acoustic transducers configured with transducer elements disposed on an arch ar arcuate shaped member adapted to fit in juxtaposition around a tubular. The arcuate shaped member is adapted with conductors to provide a voltage to the transducer elements.  One embodiment uses a metallic arcuate shaped member. Embodiments implemented as sources are used to excite borehole acoustic modes. Some embodiments provide phased array acoustic energy excitation/signal reception. The transducers are covered with a sealer in a liquid-free configuration and shields are used to protect the transducers.
Patent CA-2492093-A1 (CA)
Title: Topical treatment of skin diseases
Inventor: HOPPMANN JOACHIM
IPC: C07D401/12
Filed: 2003-07-10
Abstract: The present invention relates to a method for the treatment of an inflammatory and/or allergic skin disease comprising topically administering a substituted hydroxy indol.
Patent CA-2492977-A1 (CA)
Title: Expression receptors with 7 transmembrane domains in baculovirus-insect cell system
Inventor: RONIN CATHERINE
IPC: C07K14/705
Filed: 2003-07-22
Abstract: The invention concerns the expression in a baculovirus-insect cell system of receptors with seven transmembrane domains, in particular receptors coupled to proteins G, in particular olfactory receptors, under the transcriptional control of a promoter derived from the polyhedrin promoter by deletion of all or part of the region of said promoter extending from -1 to -12 positions relative to the initiation site of the polyhedrin translation.
Patent CA-2494116-A1 (CA)
Title: Adenoviral va1 pol iii expression system for rna expression
Inventor: LEE NAN-SOOK
IPC: C12N15/861
Filed: 2003-07-30
Abstract: An adenoviral VA1 Pol III expression system for RNAi expression is provided.
Patent CA-2496885-A1 (CA)
Inventor: NAKAMURA YUSUKE
IPC: C12Q1/68
Filed: 2003-08-19
Abstract: L'invention concerne des procédés permettant de détecter et de diagnostiquer des carcinomes colorectaux et gastriques. Dans une forme de réalisation, le procédé de diagnostic comporte l'étape consistant à déterminer le niveau d'expression d'un gène associé au cancer du côlon ou de l'estomac, qui permet de distinguer une cellule normale d'une cellule cancéreuse. L'invention concerne de plus des procédés de criblage d'agents thérapeutiques utiles dans le traitement du cancer du côlon et un procédé de vaccination d'un sujet contre le cancer du côlon ou de l'estomac.
Patent CA-2499819-A1 (CA)
Title: Novel raloxifene acid addition salts and/or solvates thereof, improved method for purification of said raloxifene acid addition salts and/or solvates thereof and pharmaceutical compositions comprising these
Inventor: PEDERSEN SOREN BOLS
IPC: C07D333/56
Filed: 2003-09-30
Abstract: Raloxifene acid addition salts or solvates thereof, having improved dissolution properties in media comprising hydrochloric acid are described, The disclosed acid addition salts or solvates thereof show an improved bioavailability in media comprising hydrochloric acid, such as the gastric juice. The acid addition salts or solvates thereof are addition salts or solvates of raloxifene and a pharmaceutical acceptable acid selected among succinic acid, lactic acid, malonic acid or sulphuric acid. Further, crystalline forms of the raloxifene salts and solvates thereof are disclosed . The raloxifene acid addition salts and/or solvates thereof are useful for th e preparation of pharmaceutical composition for oral administration capable of fast and reliable release of the active ingredients in the stomach of the patient, in particular for the treatment of cancer or osteoporosis, or for inhibiting cartilage degradation. A new method for preparation of raloxifene lactate is also disclosed.
Patent CA-2500154-A1 (CA)
Inventor: VIGNUTELLI ALBERTO
IPC: A23L1/30
Filed: 2003-09-26
Abstract: The invention relates to a method to improve the cognitive skills of a perso n by the administration of a composition-comprising (i) a synergistically effective amount of an extract of the plant Panax ginseng; and(ii) a synergistically effective amount of an extract of the plant Paullinia cupana