Patent SG-11201810299S-A (SG)
Title: Multivalent vaccines against major swine viral diseases
Inventor: PRABAKARAN MOOKKAN
IPC: C12N7/01
Filed: 2017-05-11
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1#111011110111010101111101011111001111111111111111111111111111111111111111111 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\" WO 2017/200484 Al 23 November 2017 (23.11.2017) WIPO I PCT (51) International Patent Classification: (74) Agent: MATTEUCCI, Gianfranco; Marks & Clerk Sin- C12N 7/01 (2006.01) A61K 39/187 (2006.01) gapore LLP, Tanjong Pagar, P 0 Box 636, Singapore C12N 15/869 (2006.01) A61K 39/245 (2006.01) 910816 (SG). A61K 35/763 (2015.01) A61K 39/295 (2006.01) (81) Designated States (unless otherwise indicated, for every (21) International Application Number: kind of national protection available): AE, AG, AL, AM, PCT/SG2017/050246 AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, (22) International Filing Date: CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, 11 May 2017 (11.05.2017) DZ, EC, EE, EG, ES, FL GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, (25) Filing Language: English KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, (26) Publication Language: English MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, (30) Priority Data: SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, 62/338,939 19 May 2016 (19.05.2016) US TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (71) Applicant: TEMASEK LIFE SCIENCES LABORATO- (84) Designated States (unless otherwise indicated, for every RY LIMITED [SG/SG]; 1 Research Link, National Uni- kind of regional protection available): ARIPO (BW, GH, versity of Singapore, Singapore 117604 (SG). GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (72) Inventors: PRABAKARN, Mookan; c/o TEMASEK UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, LIFE SCIENCES LABORATORY LIMITED, 1 Research — EE, ES, FL FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, Link, National University of Singapore, Singapore 117604 — MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, = (SG). RUI, Tan Yun; c/o TEMASEK LIFE SCIENCES TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, LABORATORY LIMITED, 1 Research Link, National KM, ML, MR, NE, SN, TD, TG). University of Singapore, Singapore 117604 (SG). (54) Title: MULTIVALENT VACCINES AGAINST MAJOR SWINE VIRAL DISEASES = = = Recombinant live IR TR = attenuated PRV Bertha = = = = = = genome — BG14 polyA eGH polyA SV40 polyA ---- = Tetravalent PRV - (PRV-PRRSV- .„„„„... = PCV2-CSF) = Trivalent PRV r , 1-1 (PRV-PCV2-CSF) :. iik 71' GC 71' 0 0 ei IN .---- (57) : The present invention relates to ,-1 vaccine against major swine viral diseases. In 0 containing antigens derived from porcine circovirus, ei syndrome virus. ', ..,,,, ! „......... \"\" t . r: \"q ' .. NgG 11 g G gD CNIV ie EFla CMV ie BGH polyA SV40 polyA 111111,:.,. , • N, N-gG I C-gG gD CMV ie EFla FIGURE 1 the field of vaccines. More specifically, the present invention relates to a multivalent one embodiment, the multivalent vaccine is a recombinant pseudorabies viral vector classical swine fever virus and, optionally, porcine reproductive and respiratory [Continued on next page] WO 2017/200484 Al MIDEDIM011010101110101110010101010HEMOH1110VOIMIE Declarations under Rule 4.17: — of inventorship (Rule 4.17(iv)) Published: — with international search report (Art. 21(3)) — with sequence listing part of description (Rule 5.2(a))