baber/WOPTO huggingface dataset:
Patent CO-6251256-A2 (CO)
Title: Sales del inhibidor de janus cinasa (r)-3-(4-(7h-pirrolo[2,3-d]pirimidin-4il)1h-pirazol-1-il)-3-ciclopentilpropanitrilo
Inventor: LI HUI-YIN
IPC: C07D487/04
Filed: 2009-12-16
Abstract: 1.- Una sal caracterizada porque se selecciona de:Sal de ácido maleico de (R)-3-(4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il)-3-ciclopropanitrilo; ySal de ácido sulfúrico de (R)-3-(4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il)-3-ciclopropanitrilo; ySal de ácido fosfórico de (R)-3-(4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il)-3-ciclopropanitrilo.2.- La sal de conformidad con la reivindicación 1caracterizada porque es sal de ácido maleico de (R)-3-(4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il) -3-ciclopentilpropanitrilo.3.- La sal de conformidad con la reivindicación 1caracterizada porque es sal de ácido sulfúrico de (R)-3-(4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il)-3-ciclopentilpropanitrilo.4.- La sal de conformidad con la reivindicación 1caracterizada porque es sal de ácido fosfórico de (R)-3-(4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il)-3-ciclopentilpropanitrilo.5.- La sal de conformidad con la reivindicación 1caracterizada porque está sustancialmente aislada.6.- Un método para preparar una sal de conformidadcon cualquiera de las reivindicaciones 1 a 5 caracterizadoporque comprende combinar (R)-3-(4-(7H-pirrolo[2,3-d]pirimidin-4-il)-1H-pirazol-1-il) -3-ciclopentilpropanitrilo conácido maleico, ácido sulfúrico o ácido fosfórico.7.- Una composición caracterizada porque comprendeal menos una sal de conformidad con cualquiera de lasreivindicaciones 1 a 5 y al menos un portadorfarmacéuticamente aceptable.8.- La composición de conformidad con lareivindicación 7 caracterizada porque es adecuada paraadministración oral o tópica.9.- La composición de conformidad con lareivindicación 7 caracterizada porque es adecuada para laadministración tópica.10.- Un método para modular una actividad de JAKcaracterizado porque comprende poner en contacto JAKcon una sal de conformidad con cualquiera de lasreivindicaciones 1 a 5.11.- El método de conformidad con la reivindicación10 caracterizado porque la modulación es la inhibición.12.- Un método para tratar una enfermedad en unpaciente caracterizado porque la enfermedad estáasociada con la actividad de JAK, que comprendeadministrar al paciente una cantidad terapéuticamenteefectiva de una sal de conformidad con cualquiera de lasreivindicaciones 1 a 5.
Patent CO-6650336-A2 (CO)
Title: Nuevos antagonistas del receptor ccr2 y usos de los mismos
Inventor: EBEL HEINER
IPC: A61K31/506
Filed: 2012-06-15
Abstract: La presente invención proporciona compuestos de formula (I):Así como composiciones que los contienen, para el tratamiento de enfermedades inflamatorias, neurológicas, cardiovasculares o del sistema inmune mediadas por el receptor CCR2 (receptor 2 de quimiocina CC) tales como asma, EPOC, enfermedad aterosclerótica periférica, diabetes mellitus, fibrosis quística, enfermedad inflamatoria y de dolor neuropático.
Patent CO-6620017-A2 (CO)
Title: Método y producto para el control del olor bucal
Inventor: CONOVER DONALD
IPC: A61K8/00
Filed: 2012-12-28
Abstract: Un producto y método para el control de olores bucales y mal aliento usando un producto de cuidado oral que contiene un neutralizador de olores. El producto para uso en cuidado oral o en la boca para controlar olores bucales incluye un compuesto neutralizador de olores. En el método preferido de producción, el compuesto oral O.M. Complex es mezclado con un material de sabor concentrado. El material de sabor concentrado es adicionado en porcentajes bajos al producto durante su producción para que así el producto resultante incluya el compuesto neutralizador de olores. El producto puede ser usado de forma ordinaria por el usuario y durante el uso del compuesto oral O.M. Complex sirve para capturar y neutralizar compuestos que causan olores.
Patent CO-7121327-A2 (CO)
Title: Phch a partir de almidón
Inventor: SENTI-WENK ARMELLE
IPC: C09C1/02
Filed: 2014-10-29
Abstract: El invento se refiere a un proceso para preparar suspensiones de partículas de pigmento autoadhesivo, a una suspensión de partículas de pigmento autoadhesivo, como también a un producto de papel que comprende partículas de pigmento autoadhesivo y al uso de la suspensión de partículas de pigmento autoadhesivo en aplicaciones de papel, tales como el estucado de papel o como material de relleno.
Patent CO-7350636-A2 (CO)
Title: Vehículo que incluye un chasis de vehículo reclinable y dos ruedas delanteras
Inventor: TAKANO KAZUHISA
IPC: B62K21/00
Filed: 2015-04-23
Abstract: La presente invención proporciona un vehículo que puede mejorar la comodidad de conducción y evitar un aumento en el tamaño del vehículo completoen una dirección delantera y posterior. Un tamaño de un ángulo agudo 9L que seforma al intersectar perpendicularmente a un plano virtual con un eje superior y uneje inferior de un travesaño y una dirección arriba y abajo de un chasis de vehículoes más pequeña que los tamaños de un ángulo agudo 9TR y un ángulo agudo 0TLque se forman por una dirección de expansión y contracción de elementostelescópicos y la dirección arriba y abajo del chasis de vehículo, y un ánguloagudo 9SR y un ángulo agudo 9SL que se forman por ejes de barras laterales y ladirección arriba y abajo del chasis de vehículo. Los tamaños del ángulo agudo9TR y el ángulo agudo 9TL que se forman por la dirección de expansión ycontracción de los elementos telescópicos y la dirección arriba y abajo del chasisde vehículo son mayores que el tamaño del ángulo agudo 9L que se forma alintersectar de forma perpendicular el plano virtual con el eje superior y el ejeinferior del travesaño y la dirección arriba y abajo del chasis de vehículo, y sonequivalentes a o más pequeñas que los tamaños del ángulo agudo 9SR y elángulo agudo 9SL que se forman por los ejes de las barras laterales y la direcciónarriba y abajo del chasis de vehículo.
Patent DD-140490-A2 (DD)
Title: Hinterlueftete fassadenverkleidung
Inventor: AUSCHNER WERNER
IPC: E04B2/88
Filed: 1978-11-20
Abstract: Hinterlüftete Fassadenverkleidung aus Betonwerkstein- und
Gasbetonleisten für den Wohnungs- und Gesellschaftsbau und
Baureparaturen, Ziel der Erfindung ist es, eine Fassadenverkleidung zu
schaffen, die kosten- und zeitgünstig montiert werden kann, ohne von
der Witterung abhängig zu sein, Aufgabe ist es, ein vorgehängtes
Fassadensystem aus Betonwerkstein- und Gasbeton- oder glasierten
Keramikleisten an einer Unterkonstruktion anzubringen. Die
FassadenVerkleidung besteht aus im Strangpreß- oder Gießverfahren
hergestellten Elementen, deren Oberfläche mit Glasur oder anderen
mineralischen Beschichtungen versehen ist. Der Zwischenraum zwischen
der Verkleidung und der Fassade ist wahlweise mit einem Dämmstoff
ausgefüllt. Mit der erfindungsgemäßen Fassadenverkleidung ist eine
wetterfeste, dauerhafte und feuerwiderstandsfä
Patent EP-1023844-A2 (EP)
Inventor: EISENEGGER EDWIN
IPC: A23N17/00
Filed: 2000-01-24
Abstract: In a process to prepare animal feed in pellet form, the ingredients are first heated and conditioned before a first-stage reduction with cooling air. They are then immediately pressed into diced pellets and then coated with suitable additives, further cooled by air, prior to its release to atmosphere, passing through the waiting cold mixture of first-stage powder ingredients.  In a process to prepare animal feed in pellet form from a first-stage mixed powder or granular ingredients together with suitable additives. The ingredients are first heated and conditioned before a first-stage reduction in temperature of preferably 35 degrees C with cooling air. The ingredients are then immediately pressed into diced pellets and are then coated with suitable additives at a temperature of preferably 45 degrees C. The coated pellets are then further cooled by air which, prior to its release to atmosphere, passes through the waiting cold mixture of first-stage powder ingredients.  An Independent claim is also included for a mixer assembly (1) with a conditioner (3), a pellet form (6), an additive applicator (8), a chilling unit (7).
Patent EP-1028022-A2 (EP)
Inventor: YOSHINO TAKAHIRO
IPC: F02D29/02
Filed: 2000-02-08
Abstract: An automatic engine-stop control apparatus for
a vehicle includes a vehicle speed sensor and a
brake pedal depression sensor which are coupled to a
control unit. The control unit is programmed to
decide that the vehicle speed detected by the
vehicle speed sensor is smaller than or equal to a
predetermined stop expected speed (S6) when the brake
pedal depression sensor detects that the brake pedal
is depressed, and to decide that the vehicle is
stopped when a predetermined time period elapses
from a moment that the vehicle speed becomes smaller
than or equal to the predetermined stop expected
speed and when the depression of the brake pedal is
continued (S8-S10).
Patent EP-1027992-A2 (EP)
Inventor: TATSUMI JUNJI
IPC: B41J2/16
Filed: 2000-02-09
Abstract: A method for manufacturing a liquid discharge head
comprises the steps of providing a head main body (46)
having liquid flow paths, and an aperture surface
having flow path openings communicated with the flow
paths; providing a discharge port plate (40) having
extrusions (45) each on the circumference of an inside
opening communicated with each of the discharge ports,
being on the inner face on the side opposite to the
discharge port surface provided with discharge ports
for discharging liquid, and a base having a
substantially flat surface. For this method, the
discharge port plate is arranged in a state of these
surfaces formed integrally to be in contact; bonding
the aperture surface and the inner face to fit the
extrusions into the flow path openings by pressing the
head main body and the base in the direction of the
head main body and the base approaching each other with
the discharge port plate between them; and separating
the base from other members. With the method of
manufacture thus structure, the liquid discharge head
presents an excellent discharge efficiency by the
provision of the extrusions that enter the flow paths
from the orifice plate. It also becomes possible to
manufacture a highly reliable liquid discharge head by
a simpler manufacturing apparatus in a shorter period
of time at lower costs.
Patent EP-1072623-A2 (EP)
Inventor: LEE SUNG WOO
IPC: B41M5/155
Filed: 2000-03-14
Abstract: The present invention relates to a process for preparing polyvalent metal salts of
salicylic acid resin, comprising reacting salicylic acid or its derivative and
styrene or its derivative in the presence of zinc salt of organic carboxylic acid
and/or polyvalent metal compound at 50 to 200 °C to prepare the reaction
product, and reacting the reaction product with polyvalent metal compound; an
aqueous dispersion where the polyvalent metal salt of resin is dispersed in water;
and to a color development sheet prepared from the polyvalent metal salts of
salicylic acid resin.
Patent EP-1052449-A2 (EP)
Inventor: KALZE FRANZ-JOSEF
IPC: F21S8/12
Filed: 2000-05-08
Abstract: The headlamp has a shell-shaped reflector (1), a light source (2) associated with the reflector, a lens (3) arranged in the light path of the reflector to collect light reflected from the reflector with a convex side (4) remote from the reflector and a stop enclosing the lens. The stop is in the form of a fill-in reflector (5) for collecting the light (7) from the light source that f encloses the lens and has a focal region associated with the lens.
Patent EP-1081074-A2 (EP)
Inventor: OKADA SHINYA
IPC: B65H7/14
Filed: 2000-08-30
Abstract: A light emitting sensor (15a) emits light toward sheets
(4) carried along a carriage path (16) and the quantity of
light transmitted through each to the sheets is detected by
a light receiving sensor (15b). A predetermined sampling
number of electric signals indicative of light quantity
detected by the light receiving sensor (15b) is stored in a
memory (31). A histogram of the light quantities stored in
the memory (31) is created. A light quantity corresponding
to a maximum frequency for an underlying portion of the sheets
is detected based on the created histogram. A multiple feed
of the sheets is detected based on a variation in the light
quantity of the maximum frequency for the underlying portion.
Patent EP-1094316-A2 (EP)
Inventor: HAMMERS HANS-JOERG
IPC: G01N33/50
Filed: 2000-10-23
Abstract: Described is a method for identifying DNA replicating cells, which method comprises
the steps of adding during the cultivation of cells a halogenated pyrimidine to the
medium, preferably BrUrd, treating the harvested cells by UV irradiation,
resuspending the cells in a solution with reduced ionic strength and identifying cells
with the incorporated halogenated pyrimidine, e.g. by using labelled antibodies. This
method can be combined with the simultaneous detection of cellular markers, e.g.
surface antigens, thus, is useful for the diagnosis or prognosis of malignancies as well
as the analysis of apoptosis, proliferation and cell-cycle kinetics.
Patent EP-1108387-A2 (EP)
Inventor: YOKOYAMA HIROAKI
IPC: F24C3/08
Filed: 2000-12-15
Abstract: A burner case (14) has at least one burner (11) therein and has an upper
surface (12) formed with at least one opening (13). A flame produced by the
burner (11) is introduced externally through the opening (13) for heating an object
put on the upper surface (12) of the burner case (14). The upper surface (12) of
the burner case (14) is formed along the opening (13) with an upwardly projecting
louver (15). The louver (15) acts as a windshield for the flame. For instance,
the opening (13) is an annular opening, and the louver (15) is formed in
inclination along the annular opening at an outer edge of the annular opening.
Patent EP-1114741-A2 (EP)
Inventor: WEIGELT HORST DR
IPC: B60G17/015
Filed: 2000-12-16
Abstract: Each individual wheel (7) is connected to the machine frame by a vertically swivelling wheel support with the interposition of an adjustment device formed as a worm gearing (9). The fixed gear housing (12) of the worm gear is connected directly or indirectly to the machine frame (8) and the rotatable worm wheel (15) of the worm gear (9) is connected directly or indirectly to the wheel support (10) so that the rotary axis of the worm wheel runs coaxial to the input shaft of the wheel support. The worms of the worm gear can be driven by hydraulic or electric reversible drive motors.
Patent EP-1109112-A2 (EP)
Title: Portable radio communication terminal and expression style processing method therefor
Inventor: ONO HIROSHI
IPC: G06F3/0484
Filed: 2000-12-15
Abstract: In an expression style processing method, a
plurality of objects are stored. An expression style
format for expressing the stored objects is generated.
The generated expression style format is stored. A
portable radio communication terminal is also disclosed.
Patent EP-1031434-A2 (EP)
Inventor: SMITH KEVIN
IPC: B42B5/10
Filed: 2000-01-28
Abstract: A binding machine for binding together a number of
punched sheets of paper, the machine including
   means for temporarily retaining a wire binding
element of the kind set forth so as to allow punched
sheets to be hung thereon;   means for closing the retained wire binding element
so that the closed points come into the vicinity of the
open roots,  
wherein the means for retaining the curve binding element
includes a flap and finger plate (18) comprising a number of
projections or fingers, the flap being mounted (18a) for
pivoted movement such that the plate is pivoted away from
its equilibrium position by insertion of the binding
element (52) but returns to its equilibrium position
thereafter, thus retaining the wire binding element in a
generally horizontal orientation between the flaps and
the fingers.
Patent EP-1052722-A2 (EP)
Title: Antenna
Inventor: JOHNSON ALAN
IPC: H01Q5/10
Filed: 2000-05-11
Abstract: An antenna comprising an electrical reference plane; a planar conductive
element, the electrical reference plane and planar conductive element being
electrically coupled via a first coupling means to define a first antenna
resonant frequency; and a second coupling means arranged to provide a high
impedance path between the electrical reference plane and the planar
conductive element at the first resonant frequency and a lower impedance
path between the electrical reference plane and planar conductive element at
a second frequency to define a second antenna resonant frequency.
Patent EP-1086740-A2 (EP)
Inventor: IMANISHI YUICHIRO
IPC: B01D53/32
Filed: 2000-09-27
Abstract: An apparatus for treating harmful substances contained in a waste gas
discharged from waste burning plant includes an insulating honeycomb structural
body (11) made of ceramics containing a material having photocatalysis. Parallel
through holes (12) are formed in the honeycomb structural body, and first and
second mesh electrodes (13, 14) are arranged on respective end surfaces of the
honeycomb structural body. A pulse supply source (15) is connected across the
mesh electrodes. The waste gas is passed through the through holes in the
honeycomb structural body, while pulse corona discharge plasma is uniformly
generated along the through holes. Harmful substances contained in the waste gas
are decomposed by high energy electrons and radicals generated by the discharge
plasma, and the material having photocatalysis is excited by ultraviolet emitted from
the discharge plasma to produce active oxygen which decomposes and/or oxides the
harmful substances.
Patent EP-1094679-A2 (EP)
Inventor: USUDA MASAFUMI
IPC: H04W4/00
Filed: 2000-10-19
Abstract: A pilot channel transmission method is provided of
transmitting a pilot channel through a downlink from a base
station in a CDMA mobile communication system including
base stations. Each base station is installed in one of
a plurality of cells, uses a same frequency, and divides
its channels using orthogonal codes uniquely assigned to
the channels. Each of the cells is identified by
multiplying a spreading code assigned to each base station
by the channels spread by the orthogonal codes. In the
pilot channel transmission method, when a plurality of
orthogonal code sets, each of which includes a plurality
of spreading codes assigned thereto, using by each base
station, a pilot channel is assigned to each orthogonal
code set, and at least one of the pilot channels is
transmitted. The pilot channel can be provided with a
symbol rate higher than the minimum symbol rate defined
in the system.
Patent EP-1107504-A2 (EP)
Inventor: BENAYOUN ALAIN
IPC: H04L9/08
Filed: 2000-09-28
Abstract: The invention discloses a method of updating, in nodes on
both ends of a secure link, the encryption key they share to
encrypt and decrypt data. When having to transmit data from
one of the nodes (14) towards its peer remote node (16), a
data base (22) in the forwarding node, is first updated from
the data to be transmitted. Then, encryption is performed and
data transmitted to the peer remote node while a next-to-use
encryption key is derived from the new contents of the data
base. When received, data are decrypted with the current
value of the encryption key and the peer remote node data
base is updated identically from the received decrypted data
after which a next-to-use encryption key is derived, thereby
obtaining in the peer remote node, a next-to-use identical
key. The data base is preferably the dictionary (46) of a
data compression/decompression system used simultaneously
with encryption/decryption to transmit data over the secure
link. While keys are frequently updated, for improved
security, the invention does not require that key updates
need to be actually distributed.
Patent EP-1194543-A2 (EP)
Inventor: KATO SEISHI
IPC: A61P29/00
Filed: 2000-06-16
Abstract: La présente invention concerne des protéines humaines à domaines hydrophobes, des ADN codant ces protéines, des vecteurs d'expression pour ces ADN, des cellules eucaryotes transformées exprimant ces ADN, et des anticorps dirigés contre ces protéines.
Patent EP-1218018-A2 (EP)
Inventor: STANTON G JOHN
IPC: A61K38/08
Filed: 2000-08-17
Abstract: La présente invention concerne des procédés utilisant des compositions qui renferment la colostrinine, un peptide constitutif de celle-ci, un analogue actif de celle-ci, ainsi que des associations de ceux-ci, comme régulateurs du stress oxydatif.
Patent EP-1203088-A2 (EP)
Title: Conditionally controlled, attenuated hiv vaccine
Inventor: SMITH STEPHEN
IPC: A61K39/00
Filed: 2000-07-25
Abstract: A live attenuated human immunodeficiency virus type 1 (HIV-1) whose replication is not constitutive but is instead conditionally regulated (such that rounds of reverse transcription with accompanying potential for error are strictly limited) might yield a paradigm that minimizes evolution to virulence and facilitate vaccine development. We have broached the concept of conditional control of HIV-1 through gain-of-function. Here, we describe the design of constitutively inactive HIV-1 genomes (HIV-DoxT and HIV-DoxSp) which can be conditionally resuscitated to an active state by tetracycline or related analogues. The HIV-DoxT construct comprises an inactivating mutation engineered into TAR, thereby rendering the virus non-responsive to Tat, a 302-bp DNA fragment (TetopT) which contains the tet-operator ligated into a position upstream of the HIV TATAA box, in both the 5' and 3' LTRs, and a reverse tetracycline-controlled activator (RTTA) coding sequence in place of the nef coding region. The HIV-DoxSp construct contains three additional Sp1 sites in the TetopT promoter upstream of the TATAA box thereby generating the promoter TetopSp. Genotypically, HIVDoxT is tat(+)tar(-)nef(-)Sp1(-) and HIVDoxSp is tat(+)tar(-)nef(-)Sp1(+). Since both genomes are genetically tar(-), they would ordinarily be expected to be wholly defective in producing viral proteins and/or particles. However, following transfection into an appropriate cell target, both proviruses, in a doxycycline-dependent fashion, capably released Gag and RT from cells. In the absence of doxycycline, no replication competent virus could be recovered. These findings suggest that the heterologous RTTA+Dox mechanism substituted effectively for Tat/TAR. These constructs should prove useful in the development of HIV-specific immunological and diagnostic reagents.
Patent EP-1366353-A2 (EP)
Inventor: KINTZIOS SPIRIDON
IPC: G01N33/48
Filed: 2000-11-16
Abstract: La présente invention concerne un procédé permettant d'indiquer la présence dans un liquide d'une matière à déceler, lequel procédé consiste: à mettre le liquide contenant la matière à déceler en contact avec une région de détection contenant une matière cellulaire; à surveiller une propriété électrique dans la région de détection; et à détecter la présence de la matière en détectant au moins une modification prédéterminée de la propriété électrique dans la région de détection. L'invention se rapporte également à un appareil permettant d'indiquer la présence dans un liquide d'une matière à déceler, qui comprend: un conteneur capable de contenir une matière cellulaire placée à l'intérieur d'une région prédéterminée dudit conteneur, ledit conteneur étant apte à mettre le liquide en contact avec une matière cellulaire contenue dans le conteneur; et un détecteur capable de détecter au moins une modification prédéterminée d'une propriété électrique dans la région prédéterminée.
Patent EP-1235613-A2 (EP)
Title: Procedes et systemes de prelevement de fluide utilisant des panneaux d'ecoulement de fluide extracorporel orientes dans une cartouche
Inventor: BURBANK JEFFREY H
IPC: A61M1/36
Filed: 2000-11-29
Abstract: On définit un premier chemin d'écoulement dans un premier panneau qui forme une partie d'un circuit de fluide extracorporel. On définit un second chemin d'écoulement dans un second panneau qui constitue également une partie du circuit de fluide extracorporel. Les premier et second panneaux sont orientés dans une cartouche de prélèvement de fluide pour être montés sous forme d'unité intégrée sur une machine de prélèvement de fluide et pour être retirés de ladite machine de prélèvement de fluide.