baber/WOPTO huggingface dataset:
Patent SG-11201806121P-A (SG)
Title: Ror2 antibody compositions and related methods
Inventor: RADER CHRISTOPH
IPC: C07K16/28
Filed: 2017-01-20
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization 1111111101111011101010111110101111101110111010111011101101011111101111011111 International Bureau .. .... ..Yejd (10) International Publication Number ..... ...1 (43) International Publication Date WO 2017/127702 Al 27 July 2017 (27.07.2017) WIPO I PCT (51) International Patent Classification: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, C07K 16/28 (2006.01) C07K 14/725 (2006.01) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FL GB, GD, GE, GH, GM, GT, (21) International Application Number: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, PCT/US2017/014370 KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, (22) International Filing Date: MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, 20 January 2017 (20.01.2017) NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, (25) Filing Language: English TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (26) Publication Language: English ZA, ZM, ZW. (30) Priority Data: (84) Designated States (unless otherwise indicated, for every 62/280,834 20 January 2016 (20.01.2016) US kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, (71) Applicant: THE SCRIPPS RESEARCH INSTITUTE TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, [US/US]; 10550 North Torrey Pines Road, La Jolla, CA TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, 92037 (US). DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, (72) Inventors: RADER, Christoph; 144 Victorian Lane, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CL CM, GA, GN, GQ, Jupiter, FL 33458 (US). PENG, Haiyong; 1200 Town Cener, #312, Jupiter, FL 33458 (US). LI, Xiuling; 853 GW, KM, ML, MR, NE, SN, TD, TG). University Blvd., #202, Jupiter, FL 33458 (US). Published: Agents: FITTING, Thomas et al.; The Scripps Research — with international search report (Art. 21(3)) (74) Institute, 10550 North Torrey Pine Road, TPC-8, La Jolla, with sequence listing part of description (Rule 5.2(a)) CA 92037 (US). Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, (81) = Title: ROR2 ANTIBODY COMPOSITIONS AND RELATED METHODS (54) ROR2 mAbs V R 19t1 C^3R1 FR2 CDa 193 CUE43 PII4 GM TOT, 4 % V„ Il ei © IN IN ei ,-1 FIG. 1 IN 1-1 (57) : The disclosure provides antibodies, antibody fragments or antigen- binding fragments, as well as related antibody N drug conjugates (ADCs) and chimeric antigen receptors (CARs), that specifically recognize human ROR2, Also provided in the dis - closure are methods of using such antibodies in various diagnostic and therapeutic applications, 0
Patent SG-11201807893Q-A (SG)
Title: Compositions and methods for treatment of type vii collagen deficiencies
Inventor: DAILEY VERNON
IPC: A61K38/39
Filed: 2017-03-16
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization MD 1111101110101011111 010111110111011110110111011111101101n III International Bureau .. .... ..Yejd ..... .....1 (10) International Publication Number (43) International Publication Date WO 2017/161180 Al 21 September 2017 (21.09.2017) WIP0 I PCT (51) (21) (22) (25) (26) (30) (71) (72) (74) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 38/00 (2006.01) A61K 38/39 (2006.01) kind of national protection available): AE, AG, AL, AM, A61K 38/17 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, International Application Number: DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, PCT/US2017/022800 HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, International Filing Date: KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, 16 March 2017 (16.03.2017) MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, Filing Language: English RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, Publication Language: English TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. Priority Data: 62/310,623 18 March 2016 (18.03.2016) US (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, Applicant: INTREXON CORPORATION [US/US]; GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, 1750 Kraft Drive, Suite 1400, Blacksburg, VA 24060 TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, (US). TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, Inventors: DAILEY, Vernon; 200 Zodiac Court, Walk- LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, ersville, MD 21793 (US). CHAKIATH, Marion; 14500 Brookmead Dr., Darnestown, MD 20874 (US). ZHANG, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, Shyuan; 18614 Thundercloud Rd., Boyds, MD 20841 GW, KM, ML, MR, NE, SN, TD, TG). (US). MASLOWSKI, John; 405 Eagleview Blvd., Exton, Published: PA 19341 (US). MALYALA, Anna; 405 Eagleview — with international search report (Art. 21(3)) Blvd., Exton, PA 19341 (US). — with sequence listing part of description (Rule 5.2(a)) Agent: HAAG, Thomas A.; Seyfarth Shaw, LLP, 975 F Street, NM., Washington, DC 20004 (US). Title: COMPOSITIONS AND METHODS FOR TREATMENT OF TYPE VII COLLAGEN DEFICIENCIES 5'— Cap —1 : The present invention thereof and its use in a method for the treatment of Type VII collagen deficiency, such as dominant dystrophic epidermolysis. (54) \" recessive INXN-2002 Viral RNA Genome Structure 1— polyA gene or a functional vari- dystrophic epidermolysis and 1-1 .4 0 GC Il Il 1-1 IN 1-1 (57) 0 ant R U5 cPPT CMV COL7A1 AU3 R FIG. 14 relates to self-inactivating lentiviral vectors comprising the COL7A1
Patent SG-11201900714V-A (SG)
Title: Information transmission method and information transmission apparatus
Inventor: TANG HAI
IPC: H04W72/04
Filed: 2016-07-26
Abstract: ABSTRACT T he embodiments of the invention provide an information transmission method and apparatus. The method comprises: determining, from a plurality of numerologies, a target numerology, and transmitting or receiving, according to the target numerology, a synchronization signal. 41 FIG. 1
Patent SG-11201906829S-A (SG)
Title: Acrylic rubber, acrylic rubber composition, and crosslinked acrylic rubber
Inventor: FURUKO AYAKO
IPC: C08L33/08
Filed: 2018-01-26
Abstract: An acrylic rubber includes a (meth)acrylate ester monomeric unit; and a crosslinkable monomeric unit, wherein a complex 5 viscosity at 60 °C denoted as η*(60 °C) and a complex viscosity at 100 °C denoted as η*(100 °C) satisfy the following formula (1) and the following formula (2). η*(100 °C)/η*(60 °C)<0.8 (1) 10 η *(100 °C)<3500Pa• s (2)
Patent AT-387981-B (AT)
IPC: C13K13/00
Filed: 1985-01-17
Granted: 1989-04-10
Abstract: A process for the hydrothermal and enzymatic hydrolysis of straw and other plant materials is described and entails an initial hydrothermal pretreatment in which water is passed in liquid phase under pressure at temperatures between 170 and 200degreeC through the comminuted material, and subsequently the elution solution and the solid residue are enzymatically saccharified.
Patent AT-396338-B (AT)
Title: Slalom stake
IPC: A63C19/06
Filed: 1991-03-07
Granted: 1993-08-25
Abstract: The invention relates to a slalom stake having a hood 4 attached to its upper end. The danger of injury to the athlete is avoided by the fact that the hood 4 consists of a funnel-shaped component which is open towards the top and this opening can be closed by means of an inflatable elastomeric bladder 5. <IMAGE>
Patent AT-389777-B (AT)
Inventor: WALLERSTORFER KURT
IPC: G06K19/12
Filed: 1986-03-12
Granted: 1990-01-25
Abstract: Currency cards, tickets, identity cards or the like 1, which are fastened, for example, to an article of clothing of the card owners by means of fastening clips 4, can be drawn completely into the mouthpiece 6 of a checker or the like with the aid of a transport mechanism. For this purpose, the mouthpiece 6 has a means 8 for releasing the fastening clip 4 from the ticket 1. This purpose is served preferably by a magnetically actuable tappet 16 which acts upon a resiliently prestressed catch 17 engaging into a recess 18 of the ticket 1. <IMAGE>
Patent AT-397837-B (AT)
Title: Two-stroke internal combustion engine with crankcase purging
IPC: F02B33/24
Filed: 1988-03-21
Granted: 1994-07-25
Abstract: A two-stroke internal combustion engine with crankcase purging has a crank web 6 which is designed as the rotor of a centrifugal compressor with a spiral housing, which is connected by a channel to the cylinder area. In this case, main excess-flow channels 14 are directed into the cylinder area, for the purpose of reverse purging, from the precompression area 13 which is formed by the cylinder area under the piston 2 and is open towards the crankcase. In order to reduce the purging losses to a minimum, the spiral housing 9 is sealed from the crankcase 8. An additional excess-flow channel 11 leads from the spiral housing 9 into the cylinder area, to be precise on the side diametrically opposite the outlet 12. Furthermore, a fuel injection nozzle 15 is provided in the region of the spiral housing 9 and the crankcase 8 has a fresh-air insert. <IMAGE>
Patent HU-197075-B (HU)
Title: Nail storing string
Inventor: STEFFEN MARKUS
IPC: F16B15/08
Filed: 1987-03-02
Abstract: 1. A nail strip (1) having nails which are held together in parallel arrangement mutually by way of severable connecting means (8), in which respect the nails are held in guide bushes (4) having guidance regions which are circular in axial projection of the nails and the guide bushes (4) are connected together by way of the connecting means (8) projecting radially beyond the guidance regions in their axial direction, characterised in that the guidance regions are formed by annular surfaces (5) which are provided in both axial end zones of the guide bushes (4) and the diameter of which exceeds the diameter of the portion, lying between the annular surfaces, of the guide bushes (4) as well as of the head (3) of the nails.
Patent HU-191254-B (HU)
Title: Process for production of derivatives of di- and triasol-alkyl-carbonile and containing thereof medical preparatives with antimycotical effect
Inventor: ELBE HANS-LUDWIG
IPC: C07C49/00
Filed: 1984-03-02
Abstract: 1. Substituted di- or triazolylalkyl-carbinols of the general formula   see diagramm : EP0120276,P20,F1   in which A represents a nitrogen atom or the CH group ; B represents a nitrogen atom or the CH group ; X represents hydrogen and straight-chain or branched alkyl with 1 to 6 carbon atoms ; Y represents straight-chain or branched alkyl with 1 to 6 carbon atoms ; and, if X represents hydrogen, also straight-chain or branched alkenyl and alkinyl with in each case 3 to 6 carbon atoms and benzyl which is optionally mono- to trisubstituted in the phenyl part by identical or different substituents, substituents which may mentioned being : halogen, alkyl with 1 to 4 carbon atoms, alkoxy and alkylthio with in each case 1 to 4 carbon atoms, halogenoalkyl, halogenoalkoxy and halogenoalkylthio with in each case 1 to 2 carbon and 1 to 5 identical or different halogen atoms, such as preferably fluorine and chlorine atoms, nitro and cyano ; R represents phenyl which is optionally mono- to tri-substituted by identical or different substituents, preferred substituents which may be mentioned being : halogen, alkyl with 1 to 4 carbon atoms, alkoxy and alkylthio with in each case 1 to 4 carbon atoms, halogenoalkyl, halogenoalkoxy and halogenoalkylthio with in each case 1 to 2 carbon and 1 to 5 identical or different halogen atoms, such as preferably fluorine and chlorine atoms, nitro, cyano, hydroxyl, hydroxycarbonyl with 1 to 4 carbon atoms in the alkyl part, hydroximinoalkyl with 1 to 4 carbon atoms, alkoximinoalkyl with 1 to 4 carbon atoms in each alkyl part, and phenyl, phenoxy, benzyl and benzyloxy, each of which is optionally substituted by halogen and/or alkyl with 1 to 2 carbon atoms ; R furthermore preferably represents the grouping   see diagramm : EP0120276,P20,F2   wherein Alk**1 represents straight-chain or branched alkyl with 1 to 4 carbon atoms ; Alk**2 represents straight-chain or branched alkyl with 1 to 4 carbon atoms ; Alk**1 and Alk**2, together with the carbon atom to which they are bonded, represent a 3- to 7-centered cycloaliphatic ring ; and R**1 represents, straight-chain or branched alkyl with 1 to 6 carbon atoms, alkenyl with 2 to 4 carbon atoms and phenyl, phenylalkyl with 1 to 4 carbon atoms in the alkyl part, phenoxy, phenylthio, phenoxyalkyl with 1 to 4 carbon atoms in the alkyl part, phenylthioalkyl with 1 to 4 carbon atoms in the alkyl part, benzyloxy and benzylthio, each of which is optionally mono- to trisubstituted in the phenyl part by identical or different substituents, preferred possible substituents being the phenyl substituents alreadly mentioned for R.
Patent LT-4091-B (LT)
Title: A cutting tool
Inventor: ROSDAHL HANS
IPC: A01D34/73
Filed: 1996-05-30
Abstract: A cutting tool for use with a brush cutter, trimmer or like device (1) for cutting thicket, grass and like vegetation, wherein the device includes a rotary shaft (3) for receiving a cutting tool which includes a rotatable center disc (6) which can be fitted to the tool and which includes cutting blades (9) having a cutting edge (10) along the front side of the blade as seen in the direction of rotation, wherein each individual cutting blade (9) is bent down through a first angle (v) such that the rear edge of the cutting blade (9) will be located closer to the ground than the edge-provided front side (10) of the blade when the center disc is held parallel with the ground, so that as the centre disc (6) rotates air will be pressed down towards the ground and therewith causes the tool to hover or lift slightly above the ground surface.
Patent LT-4348-B (LT)
Title: Number plate for vehicle and method for making the same
Inventor: SKRICKAS VAIDOTAS JONAS
IPC: B60R13/10
Filed: 1997-09-17
Abstract: Invention relates to car recognition means and production of the same. The proposed number plate is distinguished by good reading facility, contrast and simple construction. The plate's surface is activated by light reflecting coating or film and elements bulging out are no higher than 3 mm. For ease of determination of the plate's authenticity on the reflecting coating there are introduced different colours with various coefficients of brightness. Light reflecting film to the plate is being glued by cold lamination method, by cold punching method at a pressure of 90-120 bars bulging letter and number indexes are being pressed. Indexes are painted by putting the plate through painting shafts at a speed of 6-8 m/s and dried in a temperature of 120-130 degree by Celsius or a colour film is glued using hot lamination method.
Patent RS-49617-B (RS)
Title: Tetrahydropyrido compounds
Inventor: SIMON WOLFGANG-ALEXANDER
IPC: A61K31/437
Filed: 1999-03-19
Abstract: Tetrahydropyrido compounds of formula (I)in which the substituents have the meanings mentioned in the description, are suitable for the prevention or treatment of gastrointestinal diseases.
Patent ZA-81140-B (ZA)
Title: Pyrimidine-2-sulphides and their s-oxides for use in medicine and methods of use therefor,pharmaceutical compositions containing them,processes for their preparation and such compounds when novel per se
Inventor: GACEK MIKKEL J
IPC: A61P35/00
Filed: 1981-01-09
Abstract: Compounds of the formula   <IMAGE> I  (wherein X represents a halogen atom; n is 0, 1 or 2; R1 and R2, which may be the same or different, each represents a hydrogen atom or a carboxyl, esterified carboxyl, amido or mono- or di-C1-4 alkylamido group or a C1-4 alkyl group which may if desired carry a carboxyl or esterified carboxyl group; and R3 represents a C1-32 saturated or unsaturated, straight or branched, cyclic or acyclic aliphatic group or an araliphatic or heterocyclic substituted aliphatic group, a heterocyclic group or an aryl group which groups may if desired carry one or more substituents selected from halogen atoms and oxo, nitro, hydroxy, etherified hydroxy, esterified hydroxy, primary, secondary or tertiary amino, acylamino etherified mercapto or S=O or -SO2 derivatives thereof and esterified phosphonic acid groups) and, where an acidic or basic group is present, physiologically compatible salts thereof have been found to be of use in combating abnormal cell proliferation. The compounds are prepared inter alia by oxidation of the corresponding sulfide, displacement of a leaving atom or group from the 2-position of the pyrimidine by reaction with a sulfinic acid or by ring closure of the pyrimidine ring.
Patent ZA-88258-B (ZA)
Title: Thermotropic polymer compositions
IPC: C08K7/16
Filed: 1988-01-14
Abstract: A thermoplastic polymer composition comprising a thermotropic polymer and 0.025 to 5% by weight of the composition of a finely dispersed particulate inorganic additive wherein the additive is a material having at least 95% by weight of particles with at least one dimension less than 1 micron and preferably less than 0.1 micron and is an organophilic or organophobic material which has a settling volume of at least 10 when measured in a liquid in which the particulate material is compatible. The presence of the inorganic additive in the thermotropic polymer gives rise to an improved processing behaviour.
Patent ZA-89546-B (ZA)
Title: Anastomotic device
Inventor: SKEIE EINAR
IPC: A61B17/11
Filed: 1989-01-24
Abstract: A prosthesis for use in joining hollow, e.g. tubular, organ parts or systems, said prosthesis comprising a fragmentable body defining outer organ-supporting surface parts thereon adapted to be arranged in abutting relationship with inner surface parts of the organs to be joined, said body having a compressive strength sufficiently low to allow fragmentation of the body by application of a pressure to the outer surface of the tubular organs subsequently to the joining of the same, said pressure being below a pressure causing any substantial lesion of the tissue of the tubular organ parts. The material of the prosthesis is preferably one or more degradable and/or erodable and/or water-soluble, essentially non-toxic materials which are solid at a temperature of 40 DEG C or higher, in particular 60 DEG C or higher, the material preferably being a polyether, more preferably a polyglycol, in particular polyethylene glycol such as polyethylene glycol with an average molecular weight of from 10,000 to 35,000, especially about 20,000. As shown in Fig. 3, the prosthesis (1) may have tapered outer ends (3) as well as an intermediary portion (4) between the organ-supporting parts and having a smaller diameter. In another embodiment as shown in Fig. 9 or Fig. 13, the end portions may consist of longitudinally and inwardly radially extending fins (11) to give the prosthesis tapering end portions. In a further embodiment, the prosthesis may be a section of tubing with ends cut at an oblique or right angle.
Patent ZA-90778-B (ZA)
Title: Extended release gemfibrozil composition
Inventor: GHEBRE-SELLASSIE ISAAC
IPC: A61K9/00
Filed: 1990-02-01
Abstract: A disintegratable gemfibrozil tablet providing both immediate and enteric release is compressed from a mixture of a first granulation of gemfibrozil with at least one acid-disintegratable binder and a second granulation formed from the first granulation but regranulated or coated with an alkali-disintegratable formulation of at least one substantially alkali-soluble and substantially acid-insoluble polymer.
Patent AT-389852-B (AT)
Title: Bicycle with auxiliary motor
IPC: B60L7/12
Filed: 1986-04-30
Granted: 1990-02-12
Abstract: In a bicycle with tread crank, chain drive and mechanical brake and with an auxiliary drive which is composed of a battery and an electric motor which is connected by means of a gear-shift device and has a free-wheeling diode, a high level of utility braking in conjunction with a sensitive, ergonomic control of the braking effect is to be achieved. For this purpose, connected in parallel with the brake circuit which contains the motor and the battery and has a current controller and adjustment device there is a further short-circuit brake circuit with current controller and connection to the same adjustment device. <IMAGE>
Patent AT-406908-B (AT)
Title: Slip-on (slip-over) gills (lamellas) for small convectors which can be subsequently modified
IPC: F28F1/30
Filed: 1996-12-11
Granted: 2000-10-25
Abstract: Easy-to-install gills for (small) convectors, especially for heating strips and temperature-control shells, which can be fitted by means of suitably shaped cutouts, with or without flange, and in bundles (also individually) onto their preassembled carrier elements (heating tubes, heating bars or the like) in a fashion transverse to their longitudinal axis (and can be removed again) and retained on these by means of force-closed and self- closed connections (Figure 13). <IMAGE>
Patent AT-404793-B (AT)
Title: Connecting element for adjacent board elements
Filed: 1993-10-29
Granted: 1999-02-25
Abstract: A connecting element for board elements 4, 5, which are arranged in two mounting planes 2, 3 intersecting at a mounting axis 1, adjacent to the mounting axis 1, has a fixing profile 7 which extends along the mutually adjacent edges of the board elements 4, 5 and has two fixing sections arranged at an angle to each other for the board elements 4, 5 and at least one clamping profile 10, 11 which is connected to the fixing profile 7 by at least one tensioning device 8, 9 in order to clamp the board elements 4, 5 firmly to the fixing profile 7. Provided for each board element 4, 5 is a dedicated clamping profile 10, 11, which is supported on the respective fixing section and presses the respective board element 4, 5, by means of its own tensioning device 8, 9, against a clamping face 16, arranged at a distance from the mounting axis 1, of the fixing section, the said clamping profile being supported on the respective fixing section on a supporting surface 12, 13 arranged between this clamping face 16 and the mounting axis 1, and engaging over the edge of the respective board element 4, 5 from the outside. <IMAGE>
Patent AT-378492-B (AT)
IPC: B23K37/04
Filed: 1981-02-26
Granted: 1985-08-12
Abstract: A water table and submersible conveyor system for use with an in-line material handling system, particularly a system in which the work is processed by burning, is disclosed. The water table includes opposing end walls whose top portions each define a substantially rectangular opening to accommodate a conveyor carrying a workpiece and end doors for sealing the openings having vertical slots with resilient seals mounted therein for engaging and effecting a watertight closure about sealable links of the conveyor. The water level in the water table can be raised to submerge and protect the conveyor beneath the workpiece during the burning operation.
Patent DK-159114-B (DK)
Inventor: HEGE HANS-GUENTHER
IPC: C07D491/048
Filed: 1986-05-30
Abstract: Pyridine derivatives of the formula    <IMAGE>  I  CH2CH2NHR4,  where R1 to R4 have the meanings stated in the description, and their preparation. The substances are useful for treating disorders.
Patent DK-160042-B (DK)
Inventor: BIANCHETTI ALBERTO
IPC: A61K31/435
Filed: 1984-06-20
Abstract: Methyllevallorphanium salts having peripheral antagonistic activity of formula   <IMAGE>   wherein Yn(-) represents the anion a pharmaceutically acceptable acid other than halogen and n represents the number of negative charges of said anion; a process for their preparation by exchange of the halogen ion with the Yn(-) anion; and pharmaceutical compositions containing them as active ingredients.