baber/WOPTO huggingface dataset:
Patent WO-2007001384-A9 (WO)
Inventor: LYON RICHARD E
IPC: G01N25/00
Filed: 2005-09-27
Abstract: L'invention concerne un testeur de flammabilité pour des échantillons de l'ordre du milligramme. Un tube (40) comprenant une région de pyrolyse inférieure ou pyrolyseur (42) contient un échantillon (10) qui est chauffé de façon à se dégrader thermiquement en l'absence d'oxygène ou pyrolysé pour produire des gaz combustibles. Un gaz inerte transporte les gaz combustibles jusqu'à une région de combustion supérieure ou combusteur (46) où l'oxygène est mesuré dans l'écoulement gazeux. La combustion se produit à une température à laquelle le temps de réaction des gaz combustibles est ≤ 10 secondes. Dans ces conditions, pour obtenir une combustion complète, il est nécessaire que le volume du combusteur soit petit, ce qui permet l'oxydation des gaz combustibles au moment où ils sont libérés et se sortent du pyrolyseur pour pénétrer dans le combusteur dans lequel est maintenu un écoulement essentiellement séquentiel. La combustion complète réalisée dans ce petit volume entraîne une importante réduction de la teneur en oxygène des gaz sortant du combusteur, ce qui permet d'utiliser un analyseur d'oxygène (72) simple et peu coûteux pour mesurer la teneur en oxygène des gaz sortant du combusteur.
Patent WO-2007022076-A9 (WO)
Title: Prevention de la neurodegenerescence par antibiotiques macrolides
Inventor: SHACKA JOHN J
IPC: A61K31/70
Filed: 2006-08-14
Abstract: La présente invention concerne l'utilisation d'antibiotiques macrolides pour prévenir la neurodégénérescence et pour traiter ou prévenir des affections et des états impliquant la neurodégénérescence. Sans être limité à un mécanisme spécifique d'action, dans un mode de réalisation, les antibiotiques macrolides inhibent la neurodégénérescence imputable aux dysfonctionnement lysosomal et/ou mitochondrial. L'invention concerne également l'utilisation de n'importe quel antibiotique macrolide et de ses dérivés pharmaceutiquement admis. Dans un mode de réalisation spécifique, les antibiotiques macrolides sont la bafilomycine A1, la bafilomycine B1 et la concanamycine.
Patent WO-2008067341-A9 (WO)
Inventor: SCADDEN JARROD
IPC: G02B6/38
Filed: 2007-11-28
Abstract: A hybrid fiber/copper connector assembly which permits repair of damaged fibers or copper conductors carried by a hybrid fiber/copper cable without requiring replacement of the entire connector assembly or the cable is disclosed. The hybrid fiber/copper connector assembly disclosed also allows individual hybrid fiber/copper connectors of the assembly to be converted from one gender to a different gender. The hybrid fiber/copper connector assembly disclosed also allows the individual hybrid fiber/copper connectors of the assembly to be converted from being hybrid fiber/copper connectors to being only fiber connectors or only copper connectors.
Patent WO-2008067459-A9 (WO)
Title: Polymorphismes nucléotidiques associés avec la sclérose latérale amyotrophique
Inventor: STEPHAN DIETRICH A
IPC: C12Q1/68
Filed: 2007-11-29
Abstract: Procédés permettant de déterminer la prédisposition génétique chez l'homme à développer une sclérose latérale amyotrophique (SLA). Lesdits procédés comprennent des procédés permettant de déterminer la prédisposition génétique à l'une quelconque des formes de SLA, ainsi que des procédés spécifiques permettant de déterminer la prédisposition génétique à une SLA à début précoce, à début tardif, avec atteinte bulbaire et avec atteinte des membres. Le procédé est capable de déceler la sclérose latérale amyotrophique chez l'homme ou une forme spécifique de SLA chez le sujet (à début précoce, à début tardif, avec atteinte bulbaire ou avec atteinte des membres). Le procédé est également capable de détecter chez l'homme le risque de développer une SLA. Les procédés utilisent la détection d'un ou de plusieurs blocs haplotypes comprenant des polymorphismes nucléotidiques (SNP) marqués. Dans plusieurs modes de réalisation, les procédés comprennent la détection de la présence d'un ou de plusieurs SNP marqués.
Patent WO-2013049856-A9 (WO)
Title: Renal stem cells isolated from kidney
Inventor: HARE JOSHUE M
IPC: C12N5/074
Filed: 2012-10-01
Abstract: A novel renal precursor cell is identified from kidney tissue. The cell is multipotent capable of forming renal epithelial and endothelial tissues. The cell can be amplified in culture and maintains sternness over multiple passages. This cell fulfills a major unmet need as a cell- based source for kidney regeneration or repair. Treatment of kidney diseases and disorders (e.g., g lomerularpathies and acute tubular necrosis) may be improved thereby.
Patent WO-2013096946-A9 (WO)
Title: Electromechanical flywheel cooling system
Inventor: KALEV CLAUDE MICHAEL
IPC: H02K9/19
Filed: 2012-12-23
Abstract: An electromechanical flywheel machine includes a flywheel mass and a motor-generator having a rotor rotatable about a stator wherein the stator is supported by a fluid cooled stator support. The electromechanical flywheel has the rotor encircling a stationery stator and stator windings including a field winding encircling an axis of stator rotation and an armature winding that does not encircle the axis of stator rotation.
Patent WO-2019017875-A9 (WO)
Title: Séparateurs par diélectrophorèse à dispositifs d'éjection de cellules
Inventor: SHKOLNIKOV VIKTOR
IPC: G01N35/10
Filed: 2017-07-17
Abstract: La présente invention concerne un dispositif microfluidique pouvant comprendre, dans un exemple, au moins un canal microfluidique, un séparateur par diélectrophorèse pour séparer une pluralité de cellules passant à l'intérieur du ou des canaux microfluidiques, et une résistance thermique pour éjecter au moins une cellule du dispositif microfluidique. Une cassette peut comprendre, dans un exemple, une puce couplée à un substrat de la cassette, la puce comprenant au moins un canal microfluidique, un séparateur par diélectrophorèse le long du canal microfluidique pour séparer une pluralité de cellules passant à l'intérieur du canal microfluidique, et un dispositif d'éjection pour éjecter au moins l'une des cellules dans un puits d'essai.
Patent WO-2021092116-A9 (WO)
Title: Systems and methods for registering an instrument to an image using change in instrument position data
Inventor: BARBAGLI FEDERICO
IPC: A61B34/20
Filed: 2020-11-05
Abstract: A system may comprise a processor and a memory having computer readable instructions stored thereon. The computer readable instructions, when executed by the processor, cause the system to record position data for an instrument during an image capture period and determine an instrument position change from the recorded position data. The computer readable instructions, when executed by the processor, may also cause the system to compare the instrument position change to a position change threshold and based on the comparison, determine whether to use image data captured by an imaging system during the image capture period in a registration procedure.
Patent WO-2022159477-A9 (WO)
Title: Check valve testing systems and leak detection methods using the same
Inventor: BERTRAND VINCENT
IPC: G01M13/003
Filed: 2022-01-19
Abstract: Check valve testing systems and leak detection methods using the same are disclosed. In embodiments the check valve testing system includes a check valve assembly and a pressure sensor. The check valve assembly includes a first pressure zone upstream of the check valve and a second pressure zone downstream of the check valve. An inlet valve and a drain valve may be fluidly coupled to the first pressure zone, an outlet valve may be fluidly coupled to the second pressure zone. The pressure sensor is configured to detect a fluid pressure in the second pressure zone. The controller is configured to communicatively couple to the pressure sensor, and is configured to determine whether there is a leak through the check valve, a leak downstream of then outlet valve, or a leak through the outlet valve when the inlet valve, drain valve, and outlet valve are in various conditions.
Patent DE-102012024421-A9 (DE)
Title: Vorrichtung für gemeinsamen Transport von Gasflaschen
Inventor: NOPPEN JAN
IPC: B60P3/055
Filed: 2012-12-14
Abstract: Die vorliegende Erfindung betrifft als ersten Aspekt, eine verbesserte Vorrichtung zur gemeinsamen sicheren und formstabilen Transport einer Anzahl von Gasflaschen. Die Gasflaschen bestehen im Wesentlichen aus einem zylindrischen Körper, mit einem Kopfende und einem Fußende, von denen wenigstens ein Ende einen Durchmesser hat, der wesentlich kleiner als der Durchmesser des zylindrischen Körpers ist, wobei die Vorrichtung folgendes umfasst: einem Boden, der mit einer Anzahl von miteinander gekoppelten Bodenprofile vorgesehen ist, ein Dach, dass mit einer Anzahl von miteinander gekoppelten Dachprofilen und Seitenwandteilen, die am Boden und dem Dach angebracht sind, vorgesehen ist, wobei der Boden, dass Dach und die Seitenwandteilen zusammen ein rechteckiges Volumen bilden, dass dadurch gekennzeichnet ist, dass die Dach-Profile mit Öffnungen vorgesehen sind, mit eine Form und Abmessungen zur zumindest teilweisen Aufnahme des Kopfende. Als zweiten Aspekt, betrifft die vorliegende Erfindung ein Verfahren für die gemeinsame sichere und formstabile Transportierung von Gasflaschen.
Patent CS-264691-B1 (CS)
Inventor: KOBLAS KAREL ING
IPC: A61K31/38
Filed: 1988-01-04
Abstract: Řešení se týká zvýšení analgetického
účinku kombinací analgetika s antidepresivy.
Analgetický přípravek s antidepresivem obsahující
dosulepin a ibuprofen nebo paracetamol.
Kombinace bude vhodná pro chronické algické
syndromy bez ohledu na jejich etiologii a patogenesu.
Usnadní existenci lidem s bolestmi při
nádorových onemocněních.
Patent IE-57127-B1 (IE)
Title: Reaming tool for threading machines
IPC: A62C35/10
Filed: 1986-01-10
Abstract: ® A reaming tool (40) is mountable on the tooling carriage (47) of a power driven threading machine for continuous motion displacement along two rails (48, 50) and between use and storage positions in which a reaming blade (44) of the tool (40) is respectively coaxial with a tubular workpiece to be reamed and supported laterally outwardly adjacent the tooling carriage (47). The reaming tool (40) is comprised of an elongate arm (42) carrying the reaming blade (44), and one end of the arm (42) is mounted on the tooling carriage (47) for pivotal movement of the arm (42) about a first axis (82) laterally offset and parallel to the workpiece axis (A), and a second axis (90) perpendicular to the first axis (82).
Patent CS-250758-B1 (CS)
Inventor: KVASNA DRAHOS
IPC: B41F31/16
Filed: 1985-01-23
Abstract: Farebníkový aparát umožňuje rovnoměrně
nanášať farbu na tlačovú formu.
Uvedeného účelu sa dosiahne pomoeou
dózovacích, farbových hlavic (5), ktoré sú
vytvořené ponornými valcami (6j, ovládaných
automatickým napínacím zariadením
(11) a kontaktnými valčekmi (7), ktoré sú
uložené v kalibrovacích vložkách (9). Kontaktně
valčeky (7) sú ovládané automatickým
přítlačným zariadením (10). Ponorné
válce (6), spolu s kontaktnými valčekmi
(7) sú obopnuté tenkými, pružnoelastickými
tpásmi (8). Za pomoci týchto pásov dochádza
aj k samotnej regulácii vyvádzaného
faribového sloja, ktorý sa nanáša na tlačovú
formu.
Patent IE-34918-B1 (IE)
Title: Aerosol dispensing valve assembly
IPC: B65D83/14
Filed: 1971-01-28
Abstract: 1334923 Pressurized dispensing container valves E H GREEN 19 April 1971 [10 Aug 1970] 20222/71 Heading F1R In a pressurized dispensing container valve, Fig. 2, which comprises a sprayhead 28 whose stem 34 seats in a spring biased plunger 48 reciprocably movable in a housing 36, there are provided on either the exterior surface of the plunger 48 or on the interior surface of the housing 36, more than two circumferentially spaced axially aligned teeth which during assembly are guided to mesh with a plurality of circumferentially spaced axially aligned ribs on the surface not provided with teeth so that the plunger 48 cannot rotate within the housing 36, there being, as shown, less ribs than teeth so that when assembled there are unoccupied spaces between pairs of teeth through which product may pass. The teeth 72 are on the plunger 48 and have chisel points 76 which during assembly are guided by slanting portions 86 on the housing ribs 82, 84. On its interior the plunger 48 has steps 66 which when the stem 34 is depressed communicates with an axial slot 66' in the stem to allow product which passes from a dip tube 58 held by a split ring 60 through the unoccupied spaces between pairs of teeth 72 to enter the bore of the stem for discharge. The plunger 48 has a split 80 to assist passage of the product. The stem 34 is rotatable within limits governed by a notch 68 in the lower end of the stem and by a stop 70, to vary the dispensing rate.
[GB1334923A]
Patent IE-46373-B1 (IE)
Title: Aqueous compositions for coating glass fibres
IPC: C03C25/40
Filed: 1978-01-18
Abstract: Aqueous compositions for the coating of glass fibers used particularly for textiles, a method of applying these compositions to the fibers, and the fibers themselves are disclosed. The aqueous compositions comprise at least one starch, a non-ionic lubricant, a cationic lubricant, emulsifier and at least one organo-silane from the group made up of the organo-silanes comprising an organic chain of the polyazamide type and of the organo-silanes whose organic chain contains at least one phenyl radical and at least one secondary or tertiary amine group.
Patent IE-36063-B1 (IE)
Title: Improvements in or relating to metal oxide films
IPC: C03C17/06
Filed: 1972-02-04
Abstract: 1365492 Sputtering metal oxide films TRIPLEX SAFETY GLASS CO Ltd R D KING and R HISCUTT 20 Jan 1972 [5 Feb 1971] 4234/71 Heading C7F A metal oxide film is sputtered on to a substrate 31, of e.g. glass, porcelain, silica or mica, which is kept at a temperature of 240 to 400 C, using a cathode, of e.g. Sn-In Cd-In, Sn-Sb, Sb-Te, In-Ge or In-P or In-te alloy, which is arranged in strips 271 to allow a mixture of oxygen, carbon monoxide or dioxide, and e.g. helium, neon, argon, krypton, xenon or hydrogen and nitrogen to penetrate between the cathode and substrate in a uniform concentration. The cathode and substrate are relatively moved. The gap between the strip may vary. Each strip may be hollow and water cooled, and have an earthed electrostatic shield 28. The temperature of the substrate may be controlled by a thermocouple 58. When the substrate is curved the support rails 53 may be curved Fig. 7 (not shown).
[GB1365492A]
Patent IE-34003-B1 (IE)
Title: Alkanolamine derivatives
IPC: C07C255/37
Filed: 1970-02-10
Abstract: 1-(Substd.-phenoxy)-3-isopropylamino-2-propanols as beta-adrenergic blocking agents Cpds. of gen. formula (I): (where R1 is alkyl or hydroxyalkyl; R2 is an electronegative residue esp. MeCO, EtCO, CN, MeOCO, EtOCO, NH2CO, MeNHCO, isoPr-NHCO, BuNHCO, AllylNHCO or carbazoyl; A is alkylene or alkenylene; n is 1 or 2; and R3 is H, Hal, alkyl, cycloalkyl, alkenyl, NO2, OH, alkylthio, alkoxy, alkenyloxy, aryl, aryloxy, aralkyl, aralkoxy, hydroxyalkyl, alkoxyalkyl, haloalkyl, acyl, alkoxycarbonyl, or CN and when n = 2 R3 groups may be the same or different) and the esters, condensation products with aldehydes and salts of (I).
[FR2034561A1]
Patent IE-58931-B1 (IE)
Title: 1-Ethyl-3-hydroxy-3-phenylpiperidines, process for their preparation and their use in therapy
IPC: A61K31/451
Filed: 1986-01-28
Abstract: The present invention relates to 1-alkyl-3-hydroxy-3-phenylpiperidine derivatives of the formula <IMAGE> (I) wherein R is a C2-C4 alkyl group, and their addition salts. These derivatives are useful as pharmaceuticals, especially as CNS-antidepressants. They can be prepared in accordance with the following reaction (wherein X is a halogen atom and R is defined as indicated above): <IMAGE>
[US4680302A]
Patent IE-35380-B1 (IE)
Title: Dried foodstuffs
IPC: A23L11/10
Filed: 1971-03-08
Abstract: Dried foods of vegetable origin contain at least 0.005 mole of a water soluble phytate per kg. of solids in the food. Addition of phytate enables the dried vegetables, such as peas, potatoes, and vegetable soups, to be rehydrated and cooked more rapidly and uniformly.
[FR2084385A5]
Patent IE-68676-B1 (IE)
Title: Peptide analogues with renin-inhibiting activity
Inventor: JURASZYK HORST
IPC: C07K5/08
Filed: 1991-02-15
Abstract: Peptide analogues of formula (I) and their salts are new. R1-Z-NR2-CHR3-CR4-(CH2)o-(CR5)t- (CH2)v-CE-CwH2w-R6 (I) R1 = H, -CO-CmH2m-O-R7, -CO-O-CmH2m-R7, -CO-CmH2m-R7, -SO2-R7, -CO-CmH2m-NR8R9, -CO-CmH2m-NH-C(=NH)-NH-R10, -CO-CmH2m-COOR8, -CO-CmH2m-SO3R8 or -CO-CrH2r-L(R7-CpH2p)-CnH2n-(V)y- (T)s-CmH2m-R11. Z = 0-4 gps. selected from Abu, Ada, Ala, betaAla, Arg, Asn, Asp, Bia, Cal, Dab, Gln, Glu, Gly, His, N(im)-A-His, HpH, Ile, Isoser, Leu, tert-Leu, Lys, Mal, Met, alphaNal, betaNal, Nbg, Nle, Nva, Orn, Phe, Pia, Pro, Pya, Ser, Thr, Tia, Tic, Trp, Tyr or Val. R2, R8, R9 = H or A, where A = 1-8C alkyl. R3, R7, R11 = H, A, Ar, Ar-alkyl, Het opt. substd. Het-alkyl, 4-11C cycloalkyl-alkyl, 7-14C bi- or tricycloalkyl, or 8-18C bi- or tricycloalkylalkyl. R11 also = -OR8, -NR8R9, -COOR8 or A3N+An-. R4 = (H,R12) or = O. R2 and R12 may together form -CR8R13-O-. R5 = (H,H), (H,OH), (HOAc), (H,OSiR14R15R16), (H,tetrahydro-2-pyranyloxy), or =O. R6 = H, A, CN, CH=Y, COOR7, COR7, CONR8R9, NR8R9, NH-COOR7, NH-COR7, NH-CONR8R9, NH-SO2NR8R9, OH, OR14, OAc, OSO2R14, OSiR14R15R16, tetrahydro-2-pyranyloxy, Cl, Br, I, SR7, SOR7 or SO2RSO2R7. E = -S(O)b-CH2-(CR17)c-CH2-S(O)b-, where b = 0-2. c,s,t,v,y = 0 or 1; m,n,o,p,r,w = 0-10. Two cpds. are specifically claimed, i.e. 2-((2S,3S)-3-(BOC-Phe-His-amino)-4- cyclohexyl-2-hydroxybutyl)-1,3-dithian and the corresp. -1,2,3,3-tetroxide.
Patent IE-46868-B1 (IE)
Title: Tetradeca-peptide derivatives
IPC: C07K14/575
Filed: 1978-04-19
Abstract: The tetradecapeptide  +tr  is described along with corresponding non-toxic pharmaceutically-acceptable acid addition salts as well as intermediates useful in the synthesis of the tetradecapeptide. This tetradecapeptide as well as its pharmaceutically-acceptable acid addition salts exhibit various activities including inhibition of the release of gastric acid and reduction of gut motility.
Patent IE-39364-B1 (IE)
Title: Preparation of 2,5-disbustituted benzamides
IPC: C07C315/04
Filed: 1974-04-11
Abstract: 1455595 Process for 2,5-disubstituted-benzamides SOC D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILLE - DEFRANCE 9 April 1974 [12 April 1973] 15592/74 Heading C2C A process for making compounds (I) in which A is a C 1-5 monoalkylamino or di-(C 1-5 alkyl)amino radical, or a nitrogen-attached heterocyclic saturated ring optionally containing oxygen, sulphur or additional nitrogen atom, or a heterocyclic radical of Formula (IIa) in which R is a C 1-5 alkyl or C 2-5 alkenyl radical and m is an integer of less than 4; B is a C 1-5 alkyl or C 2-5 alkenyl radical; n is 1 or 2, and X is an amino, monoalkylamino, dialkylamino, alkyl or alkenyl radical, their addition salts with pharmaceutically acceptable inorganic or organic acids, and their quaternary ammonium salts, that comprises treating a corresponding 2,5- disubstituted benzoic acid with H 2 N(CH 2 ) n A in the presence of tetraethyl pyrophosphite.
[GB1455595A]
Patent IE-46871-B1 (IE)
Title: New zootechnic and veterinary compositions
IPC: A23K1/16
Filed: 1978-04-27
Abstract: Novel zootechnical compositions and a method of upgrading domestic animals such as cattle by administering under the skin of said animals a mixture of zeranol and an anabolisant steroid of the formula  I wherein R is alkyl of 1 to 3 carbon atoms and X is selected from the group consisting of hydrogen, lower alkyl of 1 to 6 carbon atoms, lower alkenyl and lower alkynyl of 2 to 6 carbon atoms in which one of the carbon atoms may be replaced with an oxygen atom and acyl of an organic carboxylic acid of 1 to 18 carbon atoms.
Patent IE-45143-B1 (IE)
Title: Improvements in or relating to pesticides
IPC: A01N41/02
Filed: 1977-05-04
Abstract: A pesticide which is composed of a mixture of a dioxathiepin derivative of the formula  with at least one formamidine derivative of the formula  in which R1 is hydrogen or methyl, R2 is alkyl of 1 to 4 carbon atoms and X is hydrogen or methyl, or salts thereof. The mixture has a substantially higher activity against plant and animal parasites than the activity sum of the individual components. The invention embraces also a pesticide composition in which a compound as set out is at least one of the active ingredients and which in addition includes a liquid or solid carrier material.
Patent IE-46840-B1 (IE)
Title: 6-(substituted amino)-penam derivatives
IPC: A61P31/04
Filed: 1978-05-16
Abstract: 6-Amino-penam compounds, having an antimicrobial action, of the formula  (I) in which R1 is an azaoligocycloalkyl radical which is bonded via the ring nitrogen atom and contains at least one endo-bridge atom and a total of 7 to 12 ring atoms and can contain a double bond and/or, if desired, as a further ring hetero-atom, an oxygen atom, or a nitrogen atom which can link the radical X1, where X1 is hydrogen or lower alkyl, and/or, if desired, free, esterified or etherified hydroxyl which is bonded to a ring carbon atom, and in which R2 is free carboxyl or carboxyl esterified by a physiologically detachable group, and salts of such compounds, processes for their preparation, pharmaceutical preparations which contain these compounds, including mixtures of these compounds with other antimicrobial, especially antibacterial and/or antiviral, active ingredients and/or additional substances or substance mixtures which alleviate the symptoms in the case of infections, the use of the novel compounds of the formula I and their salts, and of the novel substance mixtures, for combating micro-organisms and the preparation of corresponding medicaments by non-chemical means.
Patent MA-29318-B1 (MA)
Title: Estimation de bruit a une frequence par echantillonage du bruit a d'autres frequences
Inventor: WILLEN DENNIS E
Filed: 2007-09-06
Abstract: L'INVENTION CONCERNE UN PROCÉDÉ, UN APPAREIL ET UN PROGRAMME INFORMATIQUE PERMETTANT D'AMÉLIORER LE RAPPORT SIGNAL-BRUIT D'UN SIGNAL S(T), S(T) REPRÉSENTANT LE SIGNAL ET LE BRUIT. UNE MESURE DE S(T) À UNE FRÉQUENCE D'INTÉRÊT EST OBTENUE. LES MESURES DE BRUIT DE S(T) À UNE OU PLUSIEURS FRÉQUENCES DE BRUIT AUXQUELLES LA PARTIE SIGNAL DE S(T) PRÉVUE EST RÉDUITE SONT OBTENUES. LE BRUIT À LA FRÉQUENCE D'INTÉRÊT EST ESTIMÉ À L'AIDE DES MESURES DE BRUIT AUXDITES FRÉQUENCES DE BRUIT. LE BRUIT ESTIMÉ EST SOUSTRAIT DE LA MESURE DE S(T) À LA FRÉQUENCE D'INTÉRÊT.
Patent MA-29442-B1 (MA)
Title: Papier infalsifiable ou papier special portant des elements internes de reconnaissance tactile
Inventor: OLMOS RUIZ ANTONIO
Filed: 2007-11-05
Abstract: L'INVENTION SE RAPPORTE À UN PAPIER INFALSIFIABLE OU À UN PAPIER SPÉCIAL POUVANT ÊTRE UTILISÉ COMME MONNAIE LÉGALE OU POUR TOUT AUTRE TYPE DE DOCUMENT NÉCESSITANT DES MOYENS DE RECONNAISSANCE TACTILE OU DE PRÉVENTION CONTRE LA FALSIFICATION. LEDIT PAPIER SE COMPOSE D'UNE FEUILLE DE PAPIER (1) CONTENANT DES AGENTS D'EXPANSION INCRUSTÉS (2) ET QUI PEUVENT ÊTRE CENTRÉS EN HAUTEUR OU POSITIONNÉS À PROXIMITÉ DU CÔTÉ SUPÉRIEUR ET/OU DU CÔTÉ INFÉRIEUR DE LA FEUILLE DE PAPIER (1) DE MANIÈRE À FORMER UNE FIGURE OU UNE LÉGENDE. LORSQUE DE LA PRESSION ET DE LA CHALEUR SONT APPLIQUÉES À LA FIGURE OU À LA LÉGENDE, AU COURS DE LA PHASE DE FABRICATION DU PAPIER OU AU COURS DE PROCESSUS ULTÉRIEURS, LA FEUILLE DE PAPIER SE DÉTEND (1) ET FORME UN RELIEF (3) RECOURBÉ ET CONTINU SUR LA SURFACE DU DOCUMENT.
Patent MA-31684-B1 (MA)
Title: Composition pharmaceutique contenant un antagoniste des canaux calciques de type dihydropyridine et son procédé de préparation
Inventor: KARAVAS EVANGELOS
IPC: A61K31/4422
Filed: 2010-02-17
Abstract: La présente invention porte sur la formulation de formes posologiques solides comprenant une quantité thérapeutiquement efficace d'un antagoniste des canaux calciques de type dihydropyridine, tels que la lercanidipine ou un sel de celle-ci, en combinaison avec du dioxyde de silicium colloïdal tel que l'aerosil' pour augmenter la biodisponibilité et améliorer la solubilité. L'invention porte également sur un procédé pour la préparation de ces formes posologiques par granulation par voie humide.