baber/WOPTO huggingface dataset:
Patent CA-3076094-A1 (CA)
Title: Mutated glycoprotein of vesicular stomatitis virus
Inventor: ALBERTINI AURELIE
IPC: C12N7/00
Filed: 2018-09-24
Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO : 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
Patent CA-3076354-A1 (CA)
Title: Wall system
Inventor: FRIEDLOS CHRISTOPH
IPC: E04H1/12
Filed: 2020-03-19
Abstract: A wall system includes at least one of a stud assembly, a top connector assembly, and a leveler assembly. The stud assembly is defined by a first and second upright that are attached by at least one web bracket. The web bracket includes a main body with extension arms on opposing sides.  A notch is located at or near a free end of each extension arm. The notches are to be removably inserted over an edge of a respective aperture located on each of the first and second uprights.  The top connector assembly includes a holder member to effectively raise and lower a top portion of the stud assembly. The leveler assembly includes a threaded rod to effectively raise and lower the first and second uprights relative to a base.
Patent CA-3076955-A1 (CA)
Title: Pharmaceutical forms of diazabicyclooctane derivatives and process for producing the same
Inventor: YANG KEWEI
IPC: A61K47/26
Filed: 2018-09-25
Abstract: The present invention relates to a pharmaceutical composition and a lyophilisate of a diazabicyclooctane derivative represented by Compound I, a process for producing the same and methods for using the same. (I)
Patent CA-3080267-A1 (CA)
Inventor: VIALE LUCA
IPC: B65D51/24
Filed: 2018-10-24
Abstract: The present invention relates to a recognition system for recognizing containers to be filled with a given type of product, wherein the containers (6) are equipped with a device for closing and opening the mouth (5) through which the product to be introduced into the container is designed to pass. The closing and opening device is equipped with NFC electronic identification means (21). A corresponding reading and writing device (10) for reading and writing said NFC electronic identification means (21) is provided in the station (8) for filling of the container (6) and, in view of accommodating the container and the device for closing and opening its mouth, such station is conformed with at least the area configured to receive the device for closing and opening the mouth (5) having a three-dimensional shape that mates the three- dimensional shape that the closing and opening device assumes when it is open to allow the container to be filled and/or emptied through the mouth (5).
Patent CA-3083172-A1 (CA)
Inventor: NARASIMHAN MANDAYAM
IPC: H04N21/434
Filed: 2015-05-21
Abstract: A method is provided to determine buffer parameter settings for a plurality of layers in a transport stream. Each layer includes a respective transport stream buffer parameter setting. Then, the method provides respective transport stream buffer parameter settings to individual transport stream buffers for respective layers in the plurality of layers. Then, the method buffers the respective layers in the individual transport stream buffers according to the respective transport stream buffer parameter settings. After buffering, the method combines the respective layers to form a combined bit stream.
Patent CA-3085529-A1 (CA)
Title: Control unit and method for controlling a local distribution system's outtake of heat or cold from a thermal energy distribution grid
Inventor: ROSEN PER
IPC: F24F11/30
Filed: 2018-12-20
Abstract: The disclosure relates to a method for controlling a local distribution system's outtake of heat or cold from a thermal energy distribution grid, and a control unit. The method comprises determining a base steering temperature for the local distribution system's outtake of heat from the thermal energy distribution grid, receiving, at the local distribution system, a control signal indicative of reducing the steering temperature for the local distribution system's outtake of heat from the thermal energy distribution grid, and determining a reduced steering temperature for the local distribution system's outtake of heat from the thermal energy distribution grid based on the control signal and the base steering temperature. The method further comprises determining a return temperature of a heat transfer fluid in the return, and upon the determined reduced steering temperature being lower than the return temperature, determining a temporary steering temperature being higher than the return temperature and lower than the base steering temperature, and controlling the local distribution system's outtake of heat from the distribution grid based on the temporary steering temperature
Patent CA-3085794-A1 (CA)
Title: Procede et dispositif de localisation d'une cible sur un corps humain a l'aide de caracteristiques veineuses superficielles
Inventor: ZHENG YANG
IPC: A61H39/02
Filed: 2018-12-14
Abstract: L'invention concerne un procédé et un dispositif de localisation d'une cible sur un corps humain à l'aide de caractéristiques veineuses superficielles. Sur la base du fait qu'une veine superficielle (4) et une cible de corps humain (32) ont des positions fixes l'une par rapport à l'autre et que la veine superficielle (4) est facilement observée par un dispositif d'affichage de veine (2), un modèle de localisation de position affichant à la fois la veine superficielle (4) et la cible de corps humain (32) est construit, réalisant une localisation précise de la position de la cible de corps humain (32). Le dispositif a une structure simple, est facile à utiliser et exploiter, a une précision élevée, peut être utilisé à n'importe quel angle, a une large plage d'applications et peu d'interférences à partir de l'environnement ambiant, peut effectuer une localisation de position à n'importe quel angle et n'importe quelle position, est facile à installer et à retirer et un mode approprié de moule ou de projection peut être sélectionné en fonction de différentes cibles de corps humain. La présente invention, lorsqu'elle est en utilisation clinique, fournit une localisation précise de position, réduisant le temps et l'effort requis pour obtenir une localisation de position par rapport à la réalisation de recherches répétées par des médecins reposant sur leur expérience.
Patent CA-3086161-A1 (CA)
Inventor: KOYA VIJAY
IPC: A61B18/14
Filed: 2019-02-19
Abstract: Devices, systems, and methods for regulating glucose levels, including treating diabetes, in accordance with the present disclosure may include a catheter having an expandable or inflatable portion, one or more electrodes disposed on the expandable or inflatable portion of the catheter, wherein the electrodes are configured to deliver energy to a patient's gastrointestinal tract, and a drug delivery mechanism for delivering a drug therapy subsequent to energy delivery by the electrodes. A method for regulating glucose levels according to the present disclosure may include inserting a catheter into a patient's gastrointestinal tract, positioning the catheter in a duodenum of the patient's gastrointestinal tract, expanding or inflating a portion of the catheter in the duodenum, the expandable or inflatable portion of the catheter including electrodes, applying energy to the duodenum via the electrodes to ablate tissue of the duodenum, and delivering a drug therapy to the ablated tissue of the duodenum.
Patent CA-3086383-A1 (CA)
Inventor: WEINGARTEN OREN P
IPC: A61B34/20
Filed: 2020-07-10
Abstract: A system and method for registration of a pre-procedural image data set (e.g.  CT data) or a 3D model derived therefrom with a patient's luminal structure (e.g., airways in the lungs) using intraprocedural fluoroscopic imaging techniques.
Patent CA-3088549-A1 (CA)
Inventor: PARKS RICHARD LYNN
IPC: A47J31/44
Filed: 2019-02-04
Abstract: Improvements in an agitator are disclosed. The agitator has a central body with sides that have blades that flex or bend inward upon insertion and then expand once the pass through the neck of the bottle. The sides are elongated and allow the mixer to have an orientation within the bottle. The orientation allows for a buoyancy of the mixer to break-up powder or fruit that typically floats on the surface of the liquid. The side elements can cut into fruit and pulverize power to blend the ingredient(s). A carrier or case for the mixer provides a container for the mixer to dry and further collects and water from the mixer. A removal hook allows a user to snag one of the ends or a side element. The side flexing elements of the mixer will bend inward to pass the mixer out the neck of the bottle.
Patent CA-3091189-A1 (CA)
Title: Filtre
Inventor: SPIES OLIVER
IPC: B01D29/27
Filed: 2019-02-01
Abstract: La présente invention concerne un filtre (1) pour filtrer des eaux usées, avec une ouverture d'entrée (2) destinée aux eaux usées, disposée sur le côté supérieur lors de l'utilisation conforme du filtre (1), et un élément filtrant (8) à travers lequel est filtrée l'eau traversant le filtre (1). L'invention est caractérisée en ce que l'élément filtrant (8) est réalisé avec des diamètres ou des longueurs de 200 ym pour retenir des particules ou des fibres de microplastique, et en ce que le filtre (1) comporte une structure de retenue (4) à l'aide de laquelle le filtre (1) peut être fixé au bord supérieur (5) d'un seau (6) correspondant à ce dernier par sa taille, de manière à ce que le filtre (1), en étant suspendu hors du seau (6), puisse servir de filtre de déversement pour filtrer les eaux usées s'écoulant hors du seau (6) lors du basculement du seau (6).
Patent CA-3095897-A1 (CA)
Title: Connexin 43 antibodies and use thereof
Inventor: ZHANG YANFENG
IPC: C07K16/18
Filed: 2019-04-02
Abstract: The present disclosure generally relates to compositions and methods for treating a disease or condition associated with insufficient opening of Cx43 hemichannels in osteocytes, preferably for treating cancer, cancer metastasis, osteosarcoma, osteoporosis, or osteopenia.
Patent CA-3095964-A1 (CA)
Title: Oral/enteral nutritional compositions and process of manufacturing the same
Inventor: PHAM TIEN DUAT
IPC: A23L33/00
Filed: 2019-02-20
Abstract: Oral and enteral foods and processes for manufacturing the same from either fresh ingredients or powder ingredients are disclosed comprising: a high- protein meat group having a first predetermined percentage (%) weight; a high- protein vegetable group having a second predetermined percentage (%) weight; a carbohydrate having a third predetermined percentage (%) weight; a fiber having a fourth predetermined percentage (%) weight; water having a fifth predetermined percentage (%) weight, enzyme having a sixth percentage (%) weight; and a supplement of vitamins and minerals having a seventh percentage (%) weight, all enzymatically hydrolyzed to achieve a calorie density of 1 kcal/ml; a viscosity less than 100 cP; a peptide less than l0kDa; a plurality of amino acids and vitamins.
Patent CA-3098128-A1 (CA)
Inventor: STAUSS HANS
IPC: A61K35/17
Filed: 2019-04-17
Abstract: The present invention relates to an engineered regulatory T cell (Treg) comprising a T cell receptor (TCR) which is capable of specifically binding to a myelin basic protein (MBP) peptide or variant or fragment thereof when the peptide is presented by a major histocompatibility complex (MHC) molecule. The present invention further relates to methods for providing an engineered Treg and to methods and uses of said engineered Treg and vectors and kits of vectors encoding said Treg.
Patent CA-3099630-A1 (CA)
Title: Separation des matieres soufrees
Inventor: ALLAM RODNEY JOHN
IPC: B01D53/14
Filed: 2019-05-06
Abstract: La présente invention concerne des systèmes et des procédés de séparation de matières soufrées à partir d'un flux d'alimentation à composants multiples. Les systèmes et les procédés peuvent comprendre la mise en contact du flux d'alimentation à composants multiples avec un solvant dans une colonne de mise en contact de telle sorte qu'au moins une partie de la matière soufrée est transférée du flux d'alimentation à composants multiples au solvant. Un flux d'un gaz sensiblement purifié peut ainsi être acheminé conjointement avec un flux de liquide comprenant au moins en majeure partie de la matière soufrée. Notamment, le solvant peut comprendre du dioxyde de carbone liquide, qui peut être particulièrement utile pour éliminer des matières soufrées de flux d'alimentation à composants multiples.
Patent CA-3100519-A1 (CA)
Inventor: HERZALLAH MOHAMMAD
IPC: G16B5/30
Filed: 2019-05-17
Abstract: A system for diagnosing a mental health condition. The system comprises a smart device and a device including a memory and a processor. The smart device allows a participant to perform a cognitive task and the device receives data collected from the smart device in connection with the cognitive task performed by the participant. The device determines whether the participant has the mental health condition based on the data collected and via a classification algorithm or an artificial intelligence approach. If the participant has the mental health condition, the device determines whether the participant will respond to medication for treating the mental health condition via the classification algorithm or the artificial intelligence approach.
Patent CA-3101356-A1 (CA)
Title: Hazard detector socket
Inventor: VANNEBO PER JOHAN
IPC: G08B17/00
Filed: 2018-05-29
Abstract: Disclosed is a socket for removably connecting a hazard detector to a networked alarm system, the system having a first controller which is a system controller, the socket having: a housing having a base, an electrical interface for removably receiving the detector, and a second controller which is a socket controller mounted to the base, the socket controller maintaining wireless and/or wired network communications with the system controller when the detector is connected and disconnected.
Patent CA-3102385-A1 (CA)
Title: Shippers with a constant depth
Inventor: SIMPKINS KEVIN M
IPC: B65D5/54
Filed: 2020-12-11
Abstract: ABSTRACT OF THE DISCLOSURE  A container includes a blank haying a plurality of panels foldably connected to one another and erected about an interior space, and a plurality of top flaps foldably connected to the plurality of panels to enclose a top end of the interior space, and a plurality of bottom flaps wherein each of the bottom flaps is foldably connected to a corresponding panel of plurality of panels to enclose a bottom end of the interior space. The blank includes a line of weakness pattern configured to allow a user to break the top flaps from a closed configuration enclosing the interior space to an open configuration allowing access to the interior space. Date Recue/Date Received 2020-12-11
Patent CA-3103288-A1 (CA)
Title: Method and assembly for intervention in a radioactive zone
Inventor: PONS GUILLAUME
IPC: G06F3/01
Filed: 2019-06-20
Abstract: The invention relates to a method and assembly for intervention in a radioactive zone. Said method comprises the following steps: production of a digital model representing the three-dimensional topography of the radioactive zone (1); and intervention of the at least one operator in the radioactive zone (1), the intervention step comprising at least the following substeps: repeated measurement of the radioactive radiation intensity by a portable detector (3), and determination of the spatial coordinates of the portable detector (3) at the time of the measurement; recording of a plurality of said measurements and the corresponding spatial coordinates in the digital model; and materialisation of the recorded measurements in an augmented reality device (5) worn by the at least one operator, by a plurality of discrete holographic symbols (7).
Patent CA-3104628-A1 (CA)
Title: Differential correction map for gnss
Inventor: KROEGER BRIAN
IPC: G01S19/00
Filed: 2018-11-08
Abstract: A method comprises generating for a Global Navigation Satellite System (GNSS) a differential correction map (DCM) representing a non-planar surface of differential corrections that varies across a geographical area represented by the DCM, the differential corrections being based on a reference station constellation of GNSS reference stations having respective locations spanning the geographical area, the GNSS reference stations including physical or virtual reference stations.
Patent CA-3105437-A1 (CA)
Title: Multi-layered glass
Inventor: YUKI TAKESHI
IPC: C03C27/06
Filed: 2018-07-05
Abstract: A multi-layered glass 11 in which a glass sheet 12 and a glass sheet 13 are disposed so as to form a space 15 via a spacer 16 disposed in a peripheral edge part of the glass sheet 12 and the glass sheet 13, wherein at least one low-radiation film 14 in which a Fabry-Perot interference filter is formed is disposed on one or both surfaces of a plastic film in the space 15, whereby the space 15 is divided, the low-radiation film 14 and the spacer are each sealed by a primary seal material 19 therebetween, between the glass sheets 12, 13 and the spacer 16, the glass sheets 12, 13 are sealed by a secondary seal material 20 therebetween, on the outside of the primary seal material 19 and the spacer 16, and a reinforcing material 21 is disposed inside the secondary seal material 20. This multi-layered glass has a good appearance and excellent heat insulating properties.
Patent CA-3105542-A1 (CA)
Title: Formes cristallines d'un inhibiteur de lta4h
Inventor: KORDIKOWSKI ANDREAS
IPC: C07D401/12
Filed: 2019-07-29
Abstract: La présente invention concerne diverses formes cristallines de l'acide (S)-3-amino-4-(5-(4-((5-chloro-3-fluoropyridin-2-yl)oxy)phényl)-2H-tétrazol-2-yl)butanoïque sous sa forme libre, ainsi que des compositions, un procédé de production et des procédés d'utilisation associés. Dans certains modes de réalisation, les formes cristallines contiennent également de l'eau ("hydrates"). Ces matériaux sont utiles dans le traitement de maladies et de troubles qui sont typiquement améliorés par l'inhibition de LTA4H. De telles maladies et troubles peuvent comprendre des troubles inflammatoires et auto-immuns et une inflammation des voies pulmonaires et respiratoires.
Patent CA-3107983-A1 (CA)
Title: Methods and systems for adjusting tumor mutational burden by tumor fraction and coverage
Inventor: QUINN KATIE JULIA
IPC: C12Q1/6886
Filed: 2019-07-22
Abstract: Provided herein are methods for detecting tumor mutational burden (TMB) in subjects. In one aspect, the methods include determining observed mutational counts from sequence information obtained from nucleic acids in samples from the subjects and determining a tumor fraction and/or a coverage of the nucleic acids to generate sequencing parameters. The methods also include determining an expected mutational fraction and/or an expected distribution of the expected mutational fraction given the sequencing parameters to generate an expected result, and adjusting the observed mutational count given the expected result to generate an adjusted result, thereby detecting the TMB in the subject. Other aspects are directed to methods of selecting customized therapies for treating cancer in subjects, and methods of treating cancer in subjects. Yet other aspects include related systems and computer readable media used to detect TMB in subjects.
Patent CA-3108920-A1 (CA)
Title: Improved process of preparing mrna-loaded lipid nanoparticles
Inventor: KARVE SHRIRANG
IPC: A61K31/7105
Filed: 2019-08-28
Abstract: The present invention provides an improved process for lipid nanoparticle formulation and mRNA encapsulation. In some embodiments, the present invention provides a process of encapsulating messenger RNA (mRNA) in lipid nanoparticles comprising a step of mixing a solution of pre-formed lipid nanoparticles and mRNA at a low concentration.
Patent CA-3114057-A1 (CA)
Inventor: HSU JUI-PAO
IPC: A61P3/10
Filed: 2017-05-17
Abstract: ABSTRACT OF THE DISCLOSURE Disclosed herein are methods for treating conditions and/or disorders related to hyperglycemia.      Such conditions and/or disorders related to hyperglycemia include, but are not limited to, type I, 11 diabetes mellitus, gestational diabetes, other forms diabetes, and disorders related thereto. In particular, the present invention relates to methods of using (R)-(+)-verapamil or a pharmaceutically acceptable salt thereof in the treatment of conditions and/or disorders related to hyperglycemia.    Date Recue/Date Received 2021-04-01
Patent CA-3114544-A1 (CA)
Inventor: BAY PAUL
IPC: G06F8/34
Filed: 2014-12-05
Abstract: Specifications of dataflow graphs are generated and/or combined. A sub-graph interface of a dataflow graph includes one or more flow junctions. A  flow junction representing a connection between a flow of data outside the sub-graph interface, and a flow of data inside the sub-graph interface. In some embodiments, information is processed to generate a combined dataflow graph specification, including: identifying an association between the sub-graph interface and the first dataflow graph specification, for at least a first flow junction, determining a direction associated with transferring a value of a descriptor, and transferring a value of a descriptor according to the determined direction. In some embodiments, a link is rendered between the first flow junction and a second flow junction based on user input indicating a relationship between a first descriptor and a second descriptor.
Patent CA-3115057-A1 (CA)
Title: Echafaudage pour dispositifs medicaux implantables et procedes d'utilisation de celui-ci
Inventor: SEIDNER H ARIEL
IPC: A61F2/00
Filed: 2019-10-03
Abstract: L'invention concerne des constructions d'échafaudage, des dispositifs médicaux comprenant des constructions d'échafaudage, et des procédés de fabrication et de traitement associés. La construction d'échafaudage peut comprendre un matériau biocompatible, tel qu'un polymère, un copolymère ou un hydrogel. La construction d'échafaudage peut être poreuse et au moins partiellement biorésorbable. En outre, par exemple, la construction d'échafaudage peut définir une cavité pour fixer un implant médical à l'intérieur de celle-ci.
Patent CA-3117872-A1 (CA)
Title: Clustering techniques for machine learning models
Inventor: BONDUGULA RAJKUMAR
IPC: G06N3/04
Filed: 2021-05-10
Abstract: In some aspects, systems and methods for efficiently clustering a large-scale dataset for improving the construction and training of machine-learning models, such as neural network models, are provided. A dataset used for training a neural network model configured can be clustered into a first set of clusters and a second set of clusters.  The neural network model can be constructed with a number of nodes in a hidden layer that is based on the number of clusters in the first set of clusters. The neural network can be trained based on training samples selected from the second set of clusters. In some aspects, the trained neural network model can be utilized to satisfy risk assessment queries to compute output risk indicators for target entities. The output risk indicator can be used to control access to one or more interactive computing environments by the target entities.