baber/WOPTO huggingface dataset:
Patent CR-20210677-A (CR)
Inventor: STAUFT CHARLES
IPC: C12N7/00
Filed: 2020-06-23
Abstract: La presente invención proporciona un Flavivirus modificado, como ser un virus del dengue modificado de tipo 1, 2, 3, 4, una combinación de estos o una combinación tetravalente de estos. La modificación conforme a varios aspectos de la invención resulta en una expresión reducida de proteína viral comparada con un virus parental o de origen, en donde la reducción en la expresión es el resultado de la recodificación de una o más regiones del virus. Por ejemplo, la región prM o región de envoltura (E) puede ser recodificada. En diversas realizaciones, una o más regiones son recodificadas al reducir el sesgo de par de codones o el sesgo de la utilización de codones de la secuencia que codifica la proteína. Estos flavivirus modificados son utilizados como composiciones de vacunas para proporcionar una respuesta inmunitaria protectora.
Patent CR-20220595-A (CR)
Title: Microparticles from thermomechanically degraded ptfe
Inventor: TOURVILLE DOUGLAS LEE
IPC: B29C43/24
Filed: 2021-05-25
Abstract: The present disclosure provides poly(tetrafluoroethylene) (PTFE) microparticles with a Dv50 of about 20 µm to about 30 µm and a specific surface area (SSA) of at least about 3.0 m²/g when measured by a multipoint BET method of ISO 9277. Such PTFE microparticles can be obtained via a method including thermomechanically degrading scrap PTFE in the presence of air and/or oxygen and reducing the particle size of the resultant degraded PTFE.
Patent EC-SP003725-A (EC)
Title: Metodo para tratar el mal de parkinson a travez de la administracion de (-) -5- ceto-2-n, n-d1-n-propilamino-tetrahidrotetralina
Inventor: WUSTROW DAVID JUERGEN
IPC: C09K19/32
Filed: 2000-10-19
Abstract: El mal de Parkinson se trata con un compuesto de la fórmula (gráfico), o una sal farmacéuticamente aceptables del mismo.
Patent EC-SP910791-A (EC)
Title: Caja corrugada para embalaje
Inventor: ZORNES LARRY
IPC: B65B1/00
Filed: 1991-11-07
Abstract: Una caja para embalaje formada de una cara de un material laminar que se puede doblar, tal como cartón corrugado, que incluye un panel de fondo, paneles extremos unidos mediante doblado en los costados opuestos a dicho panel de fondo, y paneles laterales unidos mediante doblado en los costados opuestos de dicho panel de fondo, estando dichos paneles laterales y extremos en posición vertical con respecto a dicho panel de fondo, y caracterizado por un miembro en forma de columna unido mediante doblado a cada lado de al menos un panel extremo, dicho miembro en forma de columna comprendiendo una primera sección que se extienda desde el mencionado panel extremo a lo largo de una parte del mencionado panel lateral y asegurado al mismo, una segunda sección conectada a la primera sección y que incluye una variedad de paneles relativamente estrechos unidos mediante doblado para formar una columna tubular que se proyecta interiormente de dicho panel lateral y espaciado de dicho panel extremo, y una tercera sección conectada a dicha segunda sección y que recubre y se asegura a la mencionada primera sección.
Patent FI-20011109-A (FI)
Inventor: HEATH JR WILLIAM FRANCIS
IPC: A61K31/55
Filed: 2001-05-28
Abstract: This invention provides novel bis-indolemaleimide macrocycle derivatives of the formula: <CHEM> The invention further provides the preparation, pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.
Patent GB-1037152-A (GB)
Abstract: 1,037,152. Trimmer capacitors. ERIE TECHNOLOGICAL PRODUCTS Inc. Feb. 11, 1965 [March 9, 1964], No. 5929/65. Heading H1M. [Also in Division F2] In a trimmer capacitor in which the movable electrode is a metal plunger 2 actuated by a screw 12, the head 22 of the screw bottoms against the frusto-conical surface 23 of the substantially tubular section 14 of bushing 4. The internal threading at the end of member 14, which is rendered resilient by having a slot 20, is held against the screw threading by a split ring 17. Further turning force applied to the screw at either limit of travel causes camming of the resilient end of member 14 to the extent permitted by the clearance 24 between the ring 17 and a collar 18.
Patent GB-1044567-A (GB)
IPC: B23Q7/10
Abstract: 1,044,567. Transferring gears. ZAHNSCHNEIDEMASCHINENFABRIK MODUL, VEB. Feb. 13, 1964, No. 6160/64. Heading B3B. [Also in Division B8] In a machine tool a device for feeding disclike workpieces to a holder 50 comprises an inclined shoot 1 and a reciprocating worktransfer slide 2 which can be swung so that the workpiece is at right angles to the shoot or to the holder. The leading workpiece gear in the shoot 1 rests in a guide having pairs of discs 33, Fig. 3 (not shown), which are rotated by a gear 32 alternately to retain and release a workpiece as the slide 2 is reciprocated. A succeeding workpiece may be engaged by spring- pressed brake-shoes 49. A freed workpiece drops into the jaws 18, 20 of the slide 2 and is retained by a plate 23. The slide 2 is then traversed by a piston-and-cylinder device 11. As the slide moves, an arm 22 travels in a slot 10 causing the slide to move angularly and lower the plate 23 which is held from axial movement. When the workpiece is aligned with a mandrel 50, it is removed from the slide and held for machining.
Patent GB-1047235-A (GB)
IPC: C07J1/00
Abstract: 1,047,235. #<SP>5(10)</SP>-6-Oxygenated steroids. SYNTEX CORPORATION. Sept. 9, 1963, No. 35483/63. Heading C2U. Novel steroids of the formulµ (wherein R and R<SP>2</SP> are hydrogen or acyl; R<SP>3</SP> is hydrogen, C 1-8  alkyl, C 2-8  alkenyl or C 2-8  alkynyl; X is keto or α-(hydroxy or acyloxy); R<SP>4</SP> is hydrogen, hydroxy or acyloxy; and T is hydrogen, α- or #-methyl, α-hydroxy or α-acyloxy; or R and T together are a #<SP>16</SP>-double bond or a 16α,17α-methylenedioxy group which may be mono- or di-substituted by hydrocarbon radicals of less than 8 carbon atoms; the acyl groups being derived from hydrocarbon carboxylic acids of less than 12 carbon atoms which are optionally substituted) and the novel 19- nor - #<SP>5</SP>(10) - androsten - 3# - ol - 6,17 - dione, are prepared by oxidizing a 5α-bromo-6#,19- oxido-steroid to give the 6,19-lactone of the 5α- bromo - 6# - hydroxy - 19 - oic acid, treating this with a strong base to give the required 19-nor-#<SP>5(10)</SP>-6α-hydroxy steroid and, if required, acylating this or oxidizing it to the 6-ketone. During the treatment with a strong base acyloxy groups, e.g. 3-acyloxy, 17-acyloxy, may be hydrolysed. 16,17-Ketonides may be converted to the corresponding diols by acid treatment, and the diols may be acylated to give the 16-acylates or re-condensed with aldehydes or Ketones. Acylation at the 3- and/or 17-positions may also be effected. 3# - Acetoxy - 5α - bromo - 6#,19 - oxido - steroids are prepared by acetylating 3#-hydroxy-#<SP>5</SP>- steioids to give the 3 acetates, treating these with N-bromoacetamide to give 3-acetoxy-5α-bromo- 6#-hydroxy-steroids, and treating these with lead tetra-acetate. Products containing a 17-keto group are converted to the corresponding 17#- hydroxy - 17α - (methyl and ethynyl) - steroids, and the ethynyl compound is reduced to the corresponding 17α-vinyl compound.
Patent GB-1050712-A (GB)
IPC: D06L4/27
Abstract: 1,050,712. Bleaching cellulosic fibres. OFFICE NATIONAL INDUSTRIEL DE L'AZOTE, Aug. 4, 1964 [July 30, 1963; June 19, 1964], No. 31158/64. Heading D1P. Unbleached natural cellulosic fibres, e.g. linen and cotton fabrics, are bleached by contacting them with an aqueous solution of pH not below 6.5 of trichlorocyanuric acid, dichlorocyanuric acid or one of its salts, or a mixture of the said acids or salts or both. If the fibres have not been desized they may be given a pre-treatment with an aqueous solution of pH below 6.5 of trichlorocyanuric acid, dichlorocyanuric acid or one of its salts, or a mixture of the said acids or salts or both, the pH there being raised to at least 6.5 by the addition of an alkali, e.g. an alkaline carbonate, bicarbonate or hydroside. If the bleaching is effected at a pH adjusted to 10 or above by the addition of an alkaline carbonate or hydroside undesized fibres may be both bleached and desized. Cyanuric acid may also be added to the bleaching bath. Bleaching may be effected at ambient temperature or at 95-100‹C.
Patent GB-1051573-A (GB)
IPC: F01B3/00
Abstract: 1,051,573. Reciprocating pump and motors. O. ECKERLE. Feb. 21, 1964 [Feb. 21, 1963], No. 7413/64. Heading F1A. In an axial cylinder pump or motor of the type in which the end face of a rotating cylinder block 3 engages the face 1 of a valve plate 2 which has a face 10 engaging the end face 9 on the casing, the end face of the block and the faces 1, 10, 9 are in a common plane and the casing and the plate 2 are located radially by a centering ring 11.
Patent GB-1228375-A (GB)
IPC: E03C1/322
Filed: 1967-06-03
Abstract: 1,228,375. Wall brackets; mounting sanitary vessels. ARMITAGE WARE Ltd. 30 Aug., 1968 [3 June, 1967], No. 25728/67. Headings A4B and A4N. An article of sanitary ware, e.g. washbasin, bidet or urinal, is secured to a wall by engagement of a wedge shaped formation 26 depending from the rear of the article in a corresponding recess defined between the wall and an inclined arm 14 of a wall mounted bracket 11, the article being anchored to the bracket by a threaded clamp 18 and the bracket and clamp being received within a pocket in the article. In one embodiment, Fig. 2, the clamp comprises two L-shaped bolts 18 each having a threaded limb engaged through a hole (16) in a bracket projection 15 and an unthreaded limb engaged in a grommeted hole 28 in the article. The bolts 18 may be splayed apart (Fig. 5). In another embodiment, Fig. 8, the clamp comprises a spindle 46 threadedly engaged in a tapped bore in a bracket projection 44. The spindle 46 has a frustro-conical boss 47 which clamps against the article when the spindle is turned by engagement of a screwdriver in its slotted lower end.
Patent GB-1228520-A (GB)
IPC: H01H9/38
Filed: 1969-11-12
Abstract: 1,228,520. Automatic circuit - breakers. SQUARE D CO. 12 Nov., 1969 [18 Nov., 1968], No. 55376/69. Heading H1N. A circuit-breaker 20, otherwise similar to that of U.K. Specification 1,145,588, is characterized by a movable contact structure 60a including one or more main contact arms 73 and an arcing contact arm 71 pivoting about parallel axes, with the first point of arm 71 located between the pivoted and free end portions of arm 73, a contact arm carrier 62a having adjusting screws 86 engaging the main contact arm or arms 73 to adjust the biasing force of spring means 78 biasing the arms 71, 73 about their respective pivot axes. Where the arcing contact arm 71 is between two main contact arms 73, two bowed leaf-springs 78 abut a bracket 80 connected to the centre tine 74b of a flexible connector 74 secured to a terminal plate 76, tine 74b carrying the arm 71, and an adjusting stud 84 passes through the carrier 62a to engage arm 71 for adjustment thereof relative to the carrier 62a and arms 73. A modified assembly using a slightly different carrier 62b comprises a single main pivoted contact arm 102, Fig. 5, and an arcing contact arm 101, pivoted thereon at 103, a U-shaped leaf-spring 109 engaging the arm 101 with one leg and the carrier 62b or 62a with the other leg, which may be secured to the carrier. Screws 86 in the carrier engage the arm 102 on either side of arm 101. In a further embodiment, Fig. 8 (not shown), the leaf-spring 109a provides the contact arm carrier and the contact pressure spring. Different pivots for the main contact arms are shown in Figs. 2, 5 and 9 (not shown). An adjustable spring 89, Fig. 2, provides lost motion for overtravel of the carriers 62a, 62b, with respect to the associated arcing contact arms. In a three-pole breaker, a cross-bar 64 is provided for conjoint operation, and the centrepole has a movable contact structure 60a and carrier 62a, whilst the outer poles have a contact structure 60b, Fig. 1 (not shown), and carrier 62b, see also Fig. 4 (not shown).
Patent GB-1228832-A (GB)
IPC: B65B15/04
Filed: 1968-05-10
Abstract: 1,228,832. Perforating strip material. STANDARD PRESSED STEEL CO. 10 May, 1968 [29 May, 1967], No. 22172/68: Heading B4B. [Also in Division B8] Holes are punched in a tape 10, e.g. of plastics material, so that material of the tape is pushed out of the plane of the tape and stretched to form short tubular sections bounding the holes, as shown. Reciprocating punches 30, 32, having stepped operative ends, work in assooiation with reciprocating blocks 31, 33, formed with bores 31a, 33a, to form the holes. The punches may also rotate. The holes are loaded with set-screws 42, 44 for subsequent setting in a workpiece.
Patent GB-1228925-A (GB)
IPC: E21B43/20
Filed: 1968-10-10
Abstract: 1,228,925. Oil wells. ELECTROTHERMIC CO. 10 Oct., 1968 [16 Oct., 1967; 30 Sept., 1968], No. 48133/68. Heading E1F. [Also in Division H5] An underground oil bearing formation is heated by the passage of electricity through water in the formation. Alternating current may be supplied through the casing and tubing of a well, with a fibre glass sleeve or spaced insulators being used to prevent contact being the casing and tubing. Connate water in the formation may be heated, while additional water containing conductive salts may be supplied from the surface through the tubing, through the annulus between the tubing or sleeve and the casing, or through a pipe between the tubing and casing. The rate of supply of water may be varied in dependence on the current flowing through the well or on whether the depth of water in the well is above or below an electric measuring instrument. Instead of the bottom of the casing and tubing acting as electrodes, a portion of the casing just above the formation may be replaced by a non-conductive sleeve or by concrete with the bottom of the tubing being connected by a centralizer to the portion of the casing within the formation so that the portions of the casing above and below the replaced portion act as electrodes. The casing may be replaced as a conductor by a tubing concentric with the other tubing and spaced therefrom by insulation. Current may be caused to flow between tubings of spaced wells. In this case if there is a conductive stratum above the formation the bottom of the casing is insulated therefrom by the casing either being coated with an epoxy resin or having a gap therein. A packer may be arranged below the gap and oil inserted above the packer and in the gap. In an example described the formation adjacent a central well is heated and oil withdrawn from the wells in an inner ring surrounding the central well. Current is then passed between the central well and the wells in the inner ring with oil being produced from wells in an outer ring. Water flood techniques may be used, or steam flood techniques used by heating the water in the formation under pressure and then releasing the pressure.
Patent GB-1229219-A (GB)
IPC: H01H21/10
Filed: 1967-12-29
Abstract: 1,229,219. Portable electric drills. COAL INDUSTRY (PATENTS) Ltd. 20 Dec., 1968 [29 Dec., 1967], No. 59095/67. Heading B3C. [Also in Division H1] A hand-held rotary drilling machine 1 of the kind wherein the grip on a handle 2 depresses a lever 3 to close a switch 6 has the switch mechanism arranged (see Division H1) such that increased pressure, due, for example, to instinctive tighter gripping when the bit becomes jammed, opens the switch, and the grip has to be fully released before the switch can again be closed. The switch 6 is in a pilot circuit which operates remote switchgear in the main power circuit.
Patent GB-1232195-A (GB)
IPC: D01D1/10
Filed: 1969-01-28
Abstract: 1,232,195. Degassing during melting, heat transfer. VICKERS-ZIMMER A.G. PLANUNG UND BAU VON INDUSTRIEANLAGEN. 28 Jan., 1969 [10 April, 1968], No. 4669/ 69. Headings B1M and B1X. A process for melting bulky scrap material formed of one or more synthetic linear high polymers comprises compressing the bulky material in a chamber to reduce its bulk volume by from 50 to 90%, heating the compressed material to melt it, and removing the molten material and gases escaping from the material from the chamber in such a manner that, within the chamber, the direction of movement of the molten material is substantially opposed to the direction of movement of the gases. In the Figure, the scrap material is delivered after drying into compression zone 1 by a conveyor 11 comprising a ribbed roller 12 and a ribbed roller 13 driven by rack 17 via free wheel 20, whereupon the scrap is compressed so that its bulk volume is reduced by from 50 to 90% by the downward movement of piston 3 and is melted as it passes between heating jackets 29 and 30. Space 40 is annular and wedge shaped. The melt passes through port 39 into chamber 41 and is drawn off through aperture 43 for further processing, e.g. by being added to a stream of fresh polymer, and then spun straight into filaments or ropes which are then made into chips. Gasses are drawn off through ventilation port 44. An overload safety device to reduce the stroke of piston 3 comprises insert 6, and pin 8 operatively connected by cup springs.
Patent GB-1232764-A (GB)
IPC: C07K1/00
Filed: 1970-02-18
Abstract: 1,232,764. #-Alanine. LONZA Ltd. 18 Feb., 1970 [19 Feb., 1969], No. 7860/70. Heading C2C. [Also in Division C3] #-Alanine is obtained by hydrolysis of poly- #-alanine with H 2 SO 4 , followed by neutralization with Ba(OH) 2 . The product is recrystallized once, yielding pure #-alanine. The poly- #-alanine is obtained by reaction of acrylonitrile with formic acid (see Division C3). Yield of pure #-alanine based on acrylonitrile is 82%.
Patent GB-1234288-A (GB)
IPC: G01G21/00
Filed: 1968-10-10
Abstract: 1,234,288. Weighing apparatus. H. CLESS. Oct. 10, 1968 [Oct. 25, 1967]. No. 48047/68. Heading G1W. A precision balance comprises a coarseweighing beam 4, for preliminary weighing, and a fine-weighing beam 2, for precision weighing, the two beams 2, 4 conjointly forming a single rigid balance beam unit when the balance is arranged for preliminary weighing. As shown, the coarseweighing beam 4 provided with a magnetic damping arrangement 12 at one end is pivotally supported by aligned knife edges 5 on notched seats 11 forming part of a vertically movable rod 1. When the rod 1 is moved to its uppermost position, for preliminary weighing, supports 3 mounted on the beam 4 lift the fine-weighing beam 2 to disengage its support knife edge 16 from a fixed plane seat 17 and bearings 7 on a linkage 8 carrying a weight support 9 and a load pan 10 are simultaneously lifted by end knife edges 6 on the beam 4. The beams 2, 4 which are then rigidly connected and which are acted upon by a spring 13 tilt by an amount roughly proportional to the weight of a load on the load pan 10, such amount being optically projected on to a screen from a scale 15. The rod 1 is then moved to its lowest position, for precision weighing, so that the fine-weighing beam 2 becomes disengaged from the beam 4 and is pivotally supported on the seat 17 while the beam 4 is held against a stop 23 by a rod 22. Lowering of the beam 4 causes the linkage 8 to disengage from the knife edges 6 and to become supported solely by a knife edge 19 on the beam 2. During precision weighing the beam 2 which is provided with an air damping device 21 and a counter weight acts independently of the beam 4 and by suitably removing weights 25 from the weight support 9 and using the scale 15 the exact weight of the load can be determined.
Patent GB-1239428-A (GB)
IPC: A61J7/00
Filed: 1968-06-28
Abstract: 1,239,428. Trays. CERBO A.B. 28 June, 1968 [30 June, 1967], No. 31006/68. Heading B8P. [Also in Divisions A4 and A5] A tray 1 for the administration of medicines in cups 6 has a peripheral flange 12 and further flanges 3 on at least one surface of the tray which define compartments 4 to receive removable stands 10 which have holes 5 for receipt of the cups. The cups 6 may be freely suspended by the stands 10 or be supported by the surface of the tray. The stands 10 may be erected from a blank, Fig. 3 (not shown).
Patent GB-1250648-A (GB)
IPC: F04B1/20
Filed: 1968-12-16
Abstract: 1,250,648. Reciprocating pumps and motors; rotary pumps. VON ROLL A. G. Dec. 16, 1968 [Dec. 15, 1967], No. 59765/68. Headings F1A and F1F. A swash-plate pump, motor or hydrostatic transmission comprises pump or motor units 1, 2 in a common housing 5 with their rotary cylinder blocks carrying inter-meshing gears 17, 18 forming a gear-pump, e.g. for supplying liquid to the units. Gear-pump body 19 is secured in the housing by a rod on which it is slidable axially for alignment with the gears, Fig. 1 (not shown). In Fig. 3 (not shown) the rod securing body 19 is hollow and is connected to working space 24 to form a supply or delivery duct. An intermediate gear may be located between gears 17 and 18 to form two gear-pumps. For operation as a transmission, the gear of the motor unit is rotatable relative to its cylinder block to permit variation in speed between the cylinder blocks.
Patent GB-1257224-A (GB)
IPC: E05C19/00
Filed: 1969-03-26
Abstract: 1,257,224. Clamps. R. L. KUSS & CO., Inc. 26 March, 1969 [13 Nov., 1968], No. 15871/69. Heading E2B. A clamp for use with an upwardly movable flexible door 13 which is windable upon a roller 12 at its lower end, comprises a baseplate 16, a two-armed lever 25 having one arm 29 shaped to extend in use in clamping position over and partly around the roller, with one end of the arm free, the lever being pivoted on the base-plate about a fixed axis passing through the lever substantially at the junction of its arms, a handle 45, and link mechanism 32, 44 between the handle and the other arm 30 of the lever for moving the lever in use to a release position in which it lies to one side of the roller and to the clamping position in which the link mechanism prevents movement of said one arm 29 from the clamping position, the arrangement being such that the centre of gravity of the lever lies on that side of the axis which is nearer the free end of the said one arm 29 when the lever is in the clamping position and on that side of the axis which is nearer the end of the said other arm 30 when the lever is in the release position. In the construction shown the link mechanism comprises a lift link 32 and an operating member 44, the lift link 32 being pivotally connected by one end portion to the lever 25 and by its other end portion to the operating member 44; the operating member is slidably disposed on the base plate and in use extends underneath the roller to the opposite side of the door to the side upon which the lever 25 is disposed and it is provided with the handle 45 to enable the lever to be pivoted between its clamping and releasing positions. The lever can also be pivoted from the side of the door upon which it is disposed since it is provided with a grip handle 33. The lift link comprises two end portions connected together by a bolt 41 having oppositely threaded end portions so that by turning the bolt the length of the lift link can be adjusted. In the securing position the lower end of the lift link abuts against a flange 47 of the base plate and is at a slight angle to the vertical so that it resists upward movement of the arm 29 of the lever 25. The lever carries a pair of rollers 37 at its free end portion which engage the roller 12 and the pivot pin 24 by which the lever is connected to bosses 23 extending from the base plate also carries rollers 27 which engage the roller 13. The base plate is releasably attached to the floor in use adjacent the door by means of jaws 19 and 20, 21 (not shown) in such a way that it can be slidably removed by sliding the base plate parallel to the axis of the roller.