baber/WOPTO huggingface dataset:
Patent WO-2021046254-A1 (WO)
Title: Liposomal spherical nucleic acid (sna) constructs for splice modulation
Inventor: SARETT SAMANTHA
IPC: A61K31/7125
Filed: 2020-09-03
Abstract: Compositions related to spherical nucleic acids (SNAs) with antisense oligonucleotides and methods of treatment of diseases and disorders are disclosed therein. In particular, the antisense oligonucleotides are targeted to a region in a pre-mRNA of interest to regulate pre-mRNA splicing.
Patent WO-2021046394-A1 (WO)
Title: Fluid reactor and fluid reactor component manufacturing
Inventor: STROBL KARLHEINZ
IPC: A61M1/16
Filed: 2020-09-04
Abstract: A fluid reactor unit includes a fluid reactor housing and a reactor core. A reactor core includes at least one reactor core assembly made from reactor core assembly parts. Reactor core assembly parts are either reactor core components or reactor core accessories. A reactor core component includes a reactor core frame and at least one reactor core element having multiple fluid channel perforations that are surrounded by an open-pore cellular network material having a bi-continuous tortuous phase. Reactor core accessories can include, but are not limited to, heat exchangers, electrically power heaters, and endplates.
Patent WO-2021067788-A1 (WO)
Title: Crispr systems with engineered dual guide nucleic acids
Inventor: GILL RYAN
IPC: C12N15/113
Filed: 2020-10-02
Abstract: The present invention relates to an engineered Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) system comprising engineered dual guide nucleic acids (e.g., RNAs) capable of activating a CRISPR- Associated (Cas) nuclease, such as a type V-A Cas nuclease. Also provided are methods of targeting, editing, and/or modifying a nucleic acid using the engineered CRISPR system, and compositions and cells comprising the engineered CRISPR system.
Patent WO-2021112953-A1 (WO)
Title: Method and apparatus for point cloud coding
Inventor: ZHANG XIANG
IPC: G06T9/00
Filed: 2020-10-07
Abstract: An apparatus for point cloud decoding includes processing circuitry. The processing circuitry receives, from a coded bitstream for a point cloud, encoded occupancy codes for nodes in an octree structure for the point cloud. The nodes in the octree structure correspond to three dimensional (3D) partitions of a space of the point cloud. Sizes of the nodes are associated with sizes of the corresponding 3D partitions. Further, the processing circuitry decodes, from the encoded occupancy codes, occupancy codes for the nodes. At least a first occupancy code for a child node of a first node is decoded without waiting for a decoding of a second occupancy code for a second node having a same node size as the first node. Then, the processing circuitry reconstructs the octree structure based on the decoded occupancy codes for the nodes, and reconstructs the point cloud based on the octree structure.
Patent WO-2021077006-A1 (WO)
Title: Membrane-perovskite films, devices, and methods of preparation
Inventor: HUANG JINSONG
IPC: G01T1/24
Filed: 2020-10-16
Abstract: The present disclosure is directed to a composite film, comprising one or more layers, each layer comprising: i. a porous membrane comprising interconnected channels; and ii. a radiation sensitive material comprising a plurality of crystals, wherein the plurality of crystals are embedded in interconnected channels of said porous membrane. In certain embodiments, the radiation sensitive material is perovskite. Methods for producing the composite films and integrating the films onto read out circuitry for digital X-ray imaging are additionally described.
Patent WO-2021087066-A1 (WO)
Inventor: POLASEK MICHAEL
IPC: C10G7/00
Filed: 2020-10-29
Abstract: Processes and systems for making recycle content hydrocarbons, including olefins, from recycled waste material. Recycle waste material may be pyrolyzed to form recycle content pyrolysis oil composition (r-pyoil), at least a portion of which may then be cracked to form a recycle content olefin composition (r-olefin). The r- olefin may then be further separated into product streams in a separation zone downstream of the cracker furnace. In some cases, presence of recycle content hydrocarbons may facilitate more efficient operation of one or more distillation columns in the separation zone, including the demethanizer.
Patent WO-2021101691-A1 (WO)
Inventor: LI QINGHUA
IPC: C04B28/14
Filed: 2020-10-30
Abstract: Disclosed are a composite gypsum board and a method of preparing composite gypsum board. The board contains at least one set gypsum layer sandwiched between two cover sheets. The set gypsum layer is formed from at least stucco and water. The stucco material generally includes a high salt impurity content, for example, when the stucco is calcined from certain sources of low-quality synthetic gypsum. For example, in some embodiments, the salts are chloride salts, e.g., sodium chloride (NaCl), potassium chloride (KCl), magnesium chloride (MgCl2), and/or calcium chloride (CaCl2). At least one of the cover sheets is composed of high absorption paper, which enhances the bond between the set gypsum layer and the cover sheet.
Patent WO-2021216118-A1 (WO)
Inventor: FERRER GUSTAVO
IPC: A61K31/4402
Filed: 2020-11-16
Abstract: Compositions for treatment or prevention of viral infections, such as influenza A and B, coronaviruses, including but not limited to COVID-19, and rhinoviruses, along with related treatment methods. Certain compositions according to preferred embodiments of the invention may comprise chlorpheniramine, xylitol, and other inactive ingredients, such as aloe vera and / or grapefruit seed extract.
Patent WO-2021102403-A1 (WO)
Inventor: KAGEY MICHAEL
IPC: C07K16/18
Filed: 2020-11-23
Abstract: A method of treating a subject suffering from a cancer, comprising the steps of obtaining a sample of a cancer cell from the subject; determining a sequence of a phosphatidylinositol 3-kinase catalytic subunit (PIK3CA) protein in the sample; and administering a first amount of a DKK1 inhibitor to the subject determined to have the sequence of PIK3CA protein that includes an activating mutation. The cancer is an epithelial endometrial cancer or an epithelial ovarian cancer.
Patent WO-2021126500-A1 (WO)
Title: Processing multi-horizon forecasts for time series data
Inventor: LIM SI JIE
IPC: G06N3/04
Filed: 2020-11-25
Abstract: Methods, systems, and apparatus, including computer storage media, for performing multi-horizon forecasting on time-series data. A method includes determining short-term temporal characteristics for respective forecasting horizons of one or more time-steps. The determining can include generating, using RNN encoders, encoder vectors based on static covariates, and time-varying input data; and predicting using one or more RNN decoders, a short-term pattern for a respective future time period. The method can also include capturing long-term temporal characteristics for the respective forecasting horizons based on the static covariates, the time-varying input data captured during the respective past time-periods, and the time-varying known future input data.
Patent WO-2021113136-A1 (WO)
Inventor: MORRIS MARY S
IPC: A61K38/28
Filed: 2020-11-25
Abstract: The disclosure provides methods of preventing or treating Type 1 diabetes in a mammalian subject, reducing risk factors associated with Type 1 diabetes, and/or reducing the likelihood or severity of Type 1 diabetes. A method of attenuating an antigenic response in a mammal to at least one Type 1 diabetes related-antigen is also provided. The methods include sublingually administering an effective amount of an insulin-related peptide to a subject.
Patent WO-2021118979-A1 (WO)
Inventor: SMITH ROBERT
IPC: A47L13/20
Filed: 2020-12-08
Abstract: A Mop Pad, A Flat Headed Mop, And A Surface Cleaning System Is Provided. The Mop Pad Comprising A Cleaning Layer Configured To Remove Contaminants From A Surface Being Cleaned. A Backing Layer Is Coupled To The Cleaning Layer, The Backing Layer Having A Fastener Configured To Couple The Backing Layer To A Mop Head. At Least One Insert Member Coupled Between At Least One Of The Backing Layer And The Cleaning Layer, The At Least One Insert Being Arranged Adjacent An End Of The Mop Pad.
Patent WO-2021126929-A1 (WO)
Title: Modified interferon-alpha-2 having reduced immunogenicity
Inventor: MUFARREGE EDUARDO FEDERICO
IPC: C07K14/56
Filed: 2020-12-16
Abstract: The present disclosure is directed to compositions comprising modified interferon-α2 polypeptides having interferon-α2 activity and reduced immunogenicity. In aspects, said modified interferon-α2 polypeptides are hyperglycosylated, such as by addition of a GM-CSF-derived peptide sequence with multiple O-glycosylation sites. Furthermore, the present disclosure provides compositions comprising a nucleic acid molecule encoding said modified interferon-α2. The present disclosure also provides compositions comprising a recombinant protein expression cell line comprising said nucleic acid molecule encoding said modified interferon-α2; wherein said recombinant protein expression cell comprises a plasmid or vector containing said nucleic acid molecule. Also disclosed are pharmaceutical compositions comprising a modified interferon-α2 having interferon-α2 activity with reduced immunogenicity, as well as methods of use of said pharmaceutical formulations for treatment of medical conditions in a subject.
Patent WO-2021133687-A1 (WO)
Title: Techniques de fonctionnement non déterministe d'un système de mémoire empilé
Inventor: PAWLOWSKI JOSEPH T
IPC: G06F3/06
Filed: 2020-12-18
Abstract: Des techniques de fonctionnement non déterministe d'un système de mémoire empilée sont concernées. Dans un exemple, un procédé de fonctionnement d'un boîtier de mémoire peut comprendre les étapes suivantes : la réception d'une pluralité de demandes d'accès à la mémoire pour un canal au niveau d'une puce logique, le renvoi de premières données à un hôte en réponse à une première demande d'accès à la mémoire de la pluralité de demandes d'accès à la mémoire, le renvoi d'une indication de données non prêtes à l'hôte en réponse à une seconde demande d'accès à la mémoire de la pluralité de demandes d'accès à la mémoire pour des secondes données, le renvoi d'un premier indice à l'hôte avec l'indication de données qui ne sont pas prêtes, le renvoi d'une indication de données prêtes avec des troisièmes données en réponse à une troisième demande d'accès à la mémoire de la pluralité de demandes d'accès à la mémoire, et le renvoi du premier indice avec l'indication de données prêtes.
Patent WO-2022150033-A1 (WO)
Title: Dispositif de stimulation nerveuse électrique transcutanée combinée et de décompression myofasciale
Inventor: STEWART DANIEL
IPC: A61H39/00
Filed: 2021-01-06
Abstract: Un dispositif de thérapie est configuré pour fournir simultanément une décompression myofasciale et une stimulation nerveuse électrique transcutanée. Le dispositif comprend une structure de coupelle capable de maintenir une pression négative à l'intérieur d'une chambre intérieure. Une pluralité de contacts conducteurs sont couplés à la structure de coupelle. Les contacts conducteurs sont disposés de manière à être au moins partiellement exposés sur une surface inférieure de la structure de coupelle.
Patent WO-2021146664-A1 (WO)
Title: Mask and removable cidal metal or cidal metal alloy insert
Inventor: KUHN PHYLLIS J
IPC: A62B23/02
Filed: 2021-01-17
Abstract: A face mask and a removable insert, the insert being constructed primarily of cidal metal or cidal metal alloy wherein the tidal metal or tidal metal alloy is the major structural component of the insert. The insert is positioned on the face mask to cover at least a portion of the wearer's mouth and nose when the mask is worn on the wearer's face. The insert has a filtering portion comprising cidal metal mesh or cidal metal alloy mesh to provide cidal action, air purification, and self-disinfection.
Patent WO-2021158530-A1 (WO)
Title: Method and device for manufacturing a monotube shock absorber
Inventor: SIODMOK TOMASZ
IPC: B23P11/00
Filed: 2021-02-02
Abstract: A method for assembling a damper with a device includes inserting a floating piston into a cartridge, filling a region of the cartridge with oil, inserting a piston-rod assembly into the cartridge, inserting a rod guide into the cartridge, coupling a damper tube to the cartridge, supplying a gas into the damper tube via a first end of the damper tube, transferring the floating piston, the piston-rod assembly, the rod guide, and the oil from the cartridge to the damper tube through the first end of the damper tube, and securing the rod guide to the damper tube.
Patent WO-2021173636-A1 (WO)
Inventor: SINGER ALON
IPC: B01L3/00
Filed: 2021-02-24
Abstract: Fluidic systems and reagent carriers suitable for storing reagents in a desirable manner are generally provided. In some embodiments, a reagent carrier stores a liquid film comprising a solid reagent and/or stores different reagents in different locations. In some embodiments, a fluidic system comprises a reagent carrier constrained such that it comprises an elongated axis positioned within 30° of a vertical axis of the fluidic reservoir.
Patent WO-2021202641-A1 (WO)
Title: A headgear shield
Inventor: ROOT THOMAS
IPC: A41D13/11
Filed: 2021-03-31
Abstract: A headgear shield (100) is disclosed, which includes a clip (102) for removable and replaceable coupling to a headgear, and a face shield (104) configured for coupling to said clip for at least partially providing a barrier between a face of an individual wearing the headgear and an ambient environment.
Patent WO-2022055553-A1 (WO)
Title: Control of execution of nfc handover operation for wi-fi direct connection
Inventor: PARK SUNG JOON
IPC: H04W4/80
Filed: 2021-04-13
Abstract: An example control method of an electronic apparatus includes, activating a near field communication (NFC) function, based on a terminal apparatus approaching within a threshold distance from an electronic apparatus and handover data being transmitted, performing an NFC handover operation, monitoring a Wi-Fi direct connection state between the terminal apparatus and the electronic apparatus, based on the Wi-Fi direct connection state being identified as a failure, inactivating the NFC function, and after a set time in a state wherein the electronic apparatus maintains the threshold distance with the terminal apparatus, reactivating the inactivated NFC function and reperforming the NFC handover operation based on the handover data.
Patent WO-2022220850-A1 (WO)
Title: Anti-slip fastener remover tool
Inventor: Kukucka Paul
IPC: B25B23/00
Filed: 2021-04-28
Abstract: An anti-slip fastener remover tool includes a torque-tool body, a plurality of paired engagement features, and an intersection point. The plurality of paired engagement features that grips the lateral surface of the stripped fastener head is radially positioned around a rotation axis of the torque-tool body. The plurality of paired engagement features, wherein each paired engagement feature is offset by 30 degrees, comprises a first engagement feature and a second engagement feature. The first engagement feature and the second engagement feature each comprises a bracing section, a cavity section, and a connector section that are adjacently connected to each other. The cavity section of the first engagement feature is adjacently connected to the cavity section of the second engagement feature. The bracing sections of the first engagement feature and the second engagement feature are oppositely positioned of each other about the cavity sections of the first and second engagement features.
Patent WO-2021242491-A1 (WO)
Title: Noise reduction of a high voltage supply voltage
Inventor: METS DENY
IPC: G05F1/46
Filed: 2021-05-05
Abstract: A method, and a high voltage (HV) system that may include a noise reduction unit (MNRU) and a bias setting unit (BSU). The HV system may receive a HV supply signal, over a high voltage supply line from a HV supply unit. The HV supply unit, the MNRU, the BSU and a HV charged particle system may share a ground. At least the MNRU may detect noise in the HV supply signal and send, though the ground, a noise compensation signal. The BSU may receive an indication about a requested value of a bias voltage, and apply the bias voltage to a noise compensated HV signal to provide a biased and noise compensated HV signal to the HV charged particle system.
Patent WO-2022055568-A1 (WO)
Inventor: DAWSON JAMES
IPC: H01R11/28
Filed: 2021-05-20
Abstract: The present disclosure relates to a connector system that provides a sealed and grounded electrical connection for a component of a power management system, like those found in a battery-powered motor vehicle. The connector system includes a male connector assembly and an adaptor assembly. The adaptor assembly includes: (i) a capacitor assembly, (ii) a female terminal assembly, and (iii) a busbar assembly. An internal electrical connection state is defined when: (a) the female terminal assembly is electrically coupled to the capacitor assembly, (b) the capacitor assembly is electrically coupled to the busbar assembly, and (c) the busbar assembly is electrically coupled to an extent of the component of the power management system. In the internal electrical connection state, the electrical couplings are sealed from the external environment which increases the operating life, durability and reliability of the adaptor assembly, the connector system and the power management system component.
Patent WO-2021262383-A1 (WO)
Inventor: WEISS AARON
IPC: G01K1/08
Filed: 2021-05-27
Abstract: A device, system, and methods are provided for remotely monitoring pump equipment. A sensor device is provided as a one-piece unit that is mechanically mounted to a pump by a single threaded connection. The sensor device includes a vibration sensor and temperature sensor. The sensor device connects to a user device via a wireless personal area network (WPAN) connection to upload a current snapshot of vibration data and temperature data for the pump equipment. An application on the user device may add location data for the time of the data collection and connects to a provider network to upload the vibration data and temperature data.
Patent WO-2022256006-A1 (WO)
Inventor: CLOTET MARTI MARC
IPC: B33Y50/00
Filed: 2021-06-02
Abstract: Selon un exemple, un procédé pour certifier des objets 3D consiste à recevoir une requête pour certifier un objet 3D imprimé par une imprimante 3D, à obtenir des données d'état d'imprimante relatives à un état enregistré de l'imprimante 3D et des données d'état prévues relatives à un état prévu de l'imprimante 3D à un moment où l'objet 3D a été imprimé, à déterminer si l'état enregistré de l'imprimante 3D est conforme à l'état prévu de l'imprimante 3D, et à approuver la requête pour certifier l'objet 3D si l'état enregistré est déterminé comme étant conforme à l'état souhaité.
Patent WO-2022191864-A1 (WO)
Title: Split-gate flash memory cell with improved control gate capacitive coupling, and method of making same
Inventor: Xing leo
IPC: H01L21/28
Filed: 2021-06-15
Abstract: A method of forming a memory device that includes forming a first insulation layer, a first conductive layer, and a second insulation layer on a semiconductor substrate, forming a trench in the second insulation layer to expose the upper surface of the first conductive layer, performing an oxidation process and a sloped etch process to reshape the upper surface to a concave shape, forming a third insulation layer on the reshaped upper surface, forming a conductive spacer on the third insulation layer, removing portions of the first conductive layer leaving a floating gate under the conductive spacer with the reshaped upper surface terminating at a side surface at a sharp edge, and forming a word line gate laterally adjacent to and insulated from the floating gate. The conductive spacer includes a lower surface that faces and matches the shape of the reshaped upper surface.
Patent WO-2021262543-A1 (WO)
Inventor: ROY SUSMIT SINGHA
IPC: C23C16/448
Filed: 2021-06-18
Abstract: Methods for selectively forming a transition metal dichalcogenide (TMDC) film comprise exposing a substrate comprising a silicon oxide-based surface and a tungsten (W) segment to a sulfur source to selectively form the transition metal dichalcogenide film with the tungsten segment relative to the silicon oxide-based surface. Chemical vapor deposition (CVD) at a temperature in a range of 350°C to 600°C is used to form the TMDC film. CVD may be conducted by low pressure CVD (LPCVD) or atmospheric pressure CVD (APCVD). Methods of making devices incorporating the TMDC films are also provided.
Patent WO-2022006043-A1 (WO)
Title: Closed loop power regulation for a transcutaneous energy system
Inventor: ROBERTS JONATHAN
IPC: A61M60/178
Filed: 2021-06-29
Abstract: A controller (28) implantable within the body of a patient as part of a left ventricular assist device (LVAD) system and a method therefore are provided. According to one aspect, the controller includes processing circuitry (36, 70, 72) configured to determine a voltage difference by determining a difference between a first voltage (64) obtained from an internal coil (18) of the controller and a target voltage (68), and is further configured to encode the voltage difference to produce an encoded voltage difference message. The internal coil is configured to transmit the encoded voltage difference message to a power transmitter (22) to enable closed loop control of power transfer from the power transmitter to the controller to drive the voltage difference toward zero.
Patent WO-2022006180-A1 (WO)
Title: Adaptive neural networks for analyzing medical images
Inventor: SHAFIEE HADI
IPC: G06T7/00
Filed: 2021-06-29
Abstract: Systems and methods are provided for medical image classification of images from varying sources. A set of microscopic medical images are acquired, and a first neural network module configured to reduce each of the set of microscopic medical images to a feature representation is generated. The first neural network module, a second neural network module, and a third neural network module are trained on at least a subset of the set of microscopic medical images. The second neural network module is trained to receive a feature representation associated with an image of the microscopic images and classify the image into one of a first plurality of output classes. The third neural network module is trained to receive the feature representation, classify the image into one of a second plurality of output classes based on the feature representation, and provide feedback to the first neural network module.
Patent WO-2022010699-A1 (WO)
Title: Device-like overlay metrology targets displaying moiré effects
Inventor: VOLKOVICH ROIE
IPC: G06T7/00
Filed: 2021-06-30
Abstract: A metrology system and metrology methods are disclosed. The metrology system comprises a set of device features on a first layer of a sample, a first set of target features on a second layer of the sample and overlapping the set of device features, and a second set of target features on the second layer of the sample and overlapping the set of device features. Relative positions of a first set of Moire fringes and a second set of Moire fringes indicate overlay error between the first layer of the sample and the second layer of the sample.