baber/WOPTO huggingface dataset:
Patent WO-2019020556-A1 (WO)
Title: Methods and systems for evaluation of immune cell infiltrate in tumor samples
Inventor: BARNES MICHAEL
IPC: C12Q1/6886
Filed: 2018-07-23
Abstract: Immune context scores are calculated for tumor tissue samples using continuous scoring functions. Feature metrics for at least one immune cell marker are calculated for a region or regions of interest, the feature metrics including at least a quantitative measure of human CD3 or total lymphocyte counts. A continuous scoring function is then applied to a feature vector including the feature metric and at least one additional metric related to an immunological biomarker, the output of which is an immune context score. The immune context score may then be plotted as a function of a diagnostic or treatment metric, such as a prognostic metric (e.g. overall survival, disease-specific survival, progression-free survival) or a predictive metric (e.g. likelihood of response to a particular treatment course). The immune context score may then be incorporated into diagnostic and/or treatment decisions.
Patent WO-2019030236-A1 (WO)
Title: Redundancy versions in a hybrid automatic repeat request, harq, process
Inventor: CHENG JUNG-FU
IPC: H04L1/18
Filed: 2018-08-07
Abstract: Apparatus and methods for performing a hybrid automatic repeat request, HARQ, process are disclosed. In one embodiment, a method in a wireless device for transmission of redundancy versions in a HARQ process includes determining, by the wireless device, a redundancy version, RV, for transmission by the wireless device, the RV being based at least on a coding rate and performing a transmission according to the determined RV. In one embodiment, a method in a network node is provided including receiving, from a wireless device, a transmission corresponding to a redundancy version, RV, the RV being based at least on a coding rate.
Patent WO-2019038282-A1 (WO)
Title: Heat exchanger plate and heat exchanger
Inventor: SANCHEZ DAVID
IPC: F28F3/04
Filed: 2018-08-21
Abstract: Plate (110) for a heat exchanger (100) between a first medium and a second medium, the plate comprising a first heat transfer surface (114) on a first side (113) of the plate, arranged to be in contact with the first medium; a second heat transfer surface (116) on a second side (115) of the plate, arranged to be in contact with the second medium; a plurality of indentations (120, 130, 140) in the plate (110; 210; 310), bulging out locally in a plate height direction (H), which plate is arranged to be stacked together with similar plates to form a heat exchanger heat plate stack. The invention is characterised in that the plate comprises a ridge-shaped indentation, arranged to form, together with a corresponding ridge-shaped indentation of an adjacent plate in said stack, a closed flow channel (105', 105'') for the first medium with a general flow direction, in that the said closed channel comprises a floor (105a) and a ceiling (105b), as viewed in the height direction, and comprises a step (105c) in the height direction along said general flow direction by the said floor and said ceiling both being offset in same height direction.
Patent WO-2019048464-A1 (WO)
Title: System for delivery of medical components to the lungs
Inventor: MØRCH YRR
IPC: A61K35/00
Filed: 2018-09-05
Abstract: The present invention relates generally to pharmaceutical formulations. Particularly, the present invention relates to a new delivery system for delivery of medical components to the lungs, and its utility in the fields of pharmaceutical formulation, drug delivery, medicine and diagnosis.
Patent WO-2019076558-A1 (WO)
Title: Balloon catheter
Inventor: RISCH FABIAN
IPC: A61B17/22
Filed: 2018-09-17
Abstract: The invention relates to a balloon catheter with a catheter shaft (3a) and an expandable balloon portion (3c) and with working means (5) for working on vascular deposits, wherein the working means comprise at least one proximally open and distally closed attachment tube (5) laid on the periphery of the balloon portion (3c).
Patent WO-2019063760-A1 (WO)
Title: Deep learning based scatter correction
Inventor: XU SHIYU
IPC: G06T11/00
Filed: 2018-09-28
Abstract: An imaging system includes a computed tomography (CT) imaging device (10) (optionally a spectral CT), an electronic processor (16, 50), and a non-transitory storage medium (18, 52) storing a neural network (40) trained on simulated imaging data (74) generated by Monte Carlo simulation (60) including simulation of at least one scattering mechanism (66) to convert CT imaging data to a scatter estimate in projection space or to convert an uncorrected reconstructed CT image to a scatter estimate in image space. The storage medium further stores instructions readable and executable by the electronic processor to reconstruct CT imaging data (12, 14) acquired by the CT imaging device to generate a scatter-corrected reconstructed CT image (42). This includes generating a scatter estimate (92, 112, 132, 162, 182) by applying the neural network to the acquired CT imaging data or to an uncorrected CT image (178) reconstructed from the acquired CT imaging data.
Patent WO-2019086639-A1 (WO)
Title: Laser à guide d'ondes creux
Inventor: LAMB ROBERT
IPC: H01S3/02
Filed: 2018-11-02
Abstract: L'invention concerne un laser comportant un boîtier constitué d'un bloc vitrocéramique. Le bloc est usiné (ou formé d'une autre manière) pour définir un ou plusieurs canaux qui agissent en tant que guide d'ondes dans deux dimensions pour la lumière à l'intérieur du résonateur laser. Les canaux s'étendent entre des cavités également formées à l'intérieur du bloc qui retiennent des composants optiques du laser, par exemple un ou plusieurs du milieu de gain, des miroirs à cavité, des réflecteurs intermédiaires, etc. Le positionnement, la forme et la taille de chaque cavité sont sur mesure pour le composant optique qu'ille contient afin que chaque composant optique soit retenu en alignement optique de manière rigide contre les côtés de la cavité.
Patent WO-2019096727-A1 (WO)
Title: Production biotechnologique améliorée de l-tryptophane
Inventor: ZENG AN-PING
IPC: C12P13/22
Filed: 2018-11-12
Abstract: L'invention porte sur la production biotechnologique de tryptophane et de ses dérivés. L'invention concerne des moyens pour une synthèse améliorée de L-tryptophane microbienne. Selon un aspect, l'invention concerne une cellule bactérienne génétiquement modifiée pour exprimer l'anindole-3-glycérol phosphate synthase, IGP, les IGP étant moins sensibles à l'inhibition ou même étant activées par anthranilate par rapport aux IGP de type sauvage de la cellule bactérienne.
Patent WO-2019105742-A1 (WO)
Title: Composant de turbomachine à refroidissement interne
Inventor: AJKUNIC ALMIR
IPC: F01D5/00
Filed: 2018-11-15
Abstract: L'invention concerne un composant de turbomachine à refroidissement interne. Ledit composant comprend un corps principal (200) comportant une première paroi d'extrémité (210), une seconde paroi d'extrémité (212) espacée de la première paroi d'extrémité (210), et une paroi latérale (220) qui s'étend entre la première paroi d'extrémité (210) et la seconde paroi d'extrémité (212) de telle sorte que la première paroi d'extrémité (210), la seconde paroi d'extrémité (212) et la paroi latérale (220) définissent un passage de refroidissement (230) s'étendant entre une entrée de fluide (202) et une sortie de fluide (204). Un banc de socles (240) comprenant une pluralité de socles (241) qui couvrent le passage de refroidissement (230) entre la première paroi d'extrémité (210) et la seconde paroi d'extrémité (212), le banc de socles (240) étant espacé de la paroi latérale (220) pour définir un canal d'écoulement (250) entre celles-ci; et un turbulateur pour faible hauteur (260) situé dans le canal d'écoulement (250), le turbulateur pour faible hauteur (260) s'étendant à mi-chemin entre la première paroi d'extrémité (210) et la seconde paroi d'extrémité (212).
Patent WO-2019129424-A1 (WO)
Title: Télévision
Inventor: IPEK IBRAHIM
IPC: H01Q1/22
Filed: 2018-11-19
Abstract: La présente invention concerne une télévision capable de communication sans fil, dans laquelle l'efficacité de transmission de signaux de communication sans fil est améliorée. La télévision de l'invention est caractérisée par au moins une antenne disposée entre un moyen de fixation et un réflecteur.
Patent WO-2019101935-A1 (WO)
Inventor: SALO ANTTI
IPC: G01R19/25
Filed: 2018-11-23
Abstract: L'invention concerne un appareil, comprenant : un premier capteur de courant de déplacement comprenant une première électrode de détection et une première électrode de garde, le premier capteur de courant de déplacement étant configuré pour mesurer un premier signal détecté en fonction de l'activité électrique du coeur d'un sujet ; un second capteur de courant de déplacement comprenant une seconde électrode de détection et une seconde électrode de garde, le second capteur de courant de déplacement étant configuré pour mesurer un second signal détecté en fonction de l'activité électrique du coeur d'un sujet ; et un circuit configuré pour traiter au moins le premier signal détecté afin de compenser des artefacts dus au mouvement du sujet.
Patent WO-2019115217-A1 (WO)
Title: Dispositif pour la fixation extravasculaire ou extraneuronale d'un implant
Inventor: KIMMIG FABIAN
IPC: A61N1/05
Filed: 2018-11-27
Abstract: L'invention concerne un dispositif pour la fixation extravasculaire ou extraneuronale d'un implant, qui peut être assemblé localement le long d'un vaisseau intracorporel ou d'un faisceau de fibres nerveuses dans le cadre d'une liaison par complémentarité de forme et/ou à force et qui est relié via au moins une alimentation et dérivation électriques à un appareil de commande pouvant être implanté, conçu séparément de l'implant et/ou à une source d'énergie pouvant être implantée. L'invention est caractérisée en ce que l'implant est relié via au moins un moyen de liaison transférant des forces de traction à un moyen de fixation séparé de l'implant, qui est conçu sous forme d'une manchette ou d'une structure hélicoïdale et auquel peut être attribuée une surface enveloppante cylindrique comprenant un espace creux cylindrique, via laquelle le moyen de fixation peut être assemblé au moins en partie localement à une zone de paroi externe du vaisseau ou du faisceau de fibres nerveuses tout en formant une liaison par complémentarité de forme et/ou à force et en ce que l'alimentation et la dérivation électriques allant à l'appareil de commande et/ou à la source d'énergie sont appliquées directement ou indirectement sur le moyen de fixation pour reprendre les forces de traction.
Patent WO-2019174774-A1 (WO)
Inventor: BÖNSCH MATTHIAS
IPC: H01R13/426
Filed: 2018-12-13
Abstract: The invention relates to a connection apparatus, use and a method for connecting a conductor end, in particular using an automatic assembly machine or robot. The connection apparatus has at least one connection means for connecting the conductor end, and also has a device directly or indirectly movable or formable by a tool of an assembly robot, which device assists in introducing the conductor on the connection means into a contact position or assists in producing such a contact position.
Patent WO-2019121798-A1 (WO)
Title: Optical security component visible in reflection, manufacture of such a component, and secure document provided with such a component
Inventor: PETITON VALÉRY
IPC: G03H1/00
Filed: 2018-12-18
Abstract: The present description concerns an optical security component (101) intended to be observed in reflection, by the naked eye, along at least one first observation face (100), comprising: a first layer (113) made from dielectric material, that is at least partially transparent in the visible range, having a first refractive index (n 1 ), said first layer comprising at least one first region (R 1 ) that is microstructured in a uniform manner in order to form a first microstructure (S 1 ); at least one first metal reflective layer (114), deposited on said at least one first microstructured region and forming one or more opaque reflective elements (O i ), each opaque reflective element forming a line with a width strictly smaller than 1 mm; at least one first transparent reflective layer (115), made from dielectric material, having a second refractive index (n 2 ), deposited on said at least one first microstructured region and forming one or more transparent reflective elements (T i ), a minimum dimension of each transparent reflective element being greater than 2 mm; a closing layer (116), made from dielectric material, that is at least partially transparent in the visible range, having a third refractive index (n 3 ) close to the first refractive index (n 1 ), covering said first layer (113) and said at least one first metal reflective layer (114) and at least one first transparent reflective layer (115), such that said closing layer is in direct contact with said first layer in the areas of said first layer free of opaque or transparent reflective elements.
Patent WO-2019206490-A1 (WO)
Title: An automated storage and retrieval system with a charging station for charging of a replaceable power supply of a container handling vehicle
Inventor: AUSTRHEIM TROND
IPC: B60S5/06
Filed: 2019-02-15
Abstract: The present invention an automated storage and retrieval system (1) comprising: a track system (108) comprising a first set of parallel tracks (110) arranged in a horizontal plane (P) and extending in a first direction (X), and a second set of parallel tracks (111) arranged in the horizontal plane (P) and extending in a second direction (Y) which is orthogonal to the first direction (X), said first and second sets of tracks (110, 110) forming a grid pattern in the horizontal plane (P) comprising a plurality of adjacent grid cells (122), each grid cell comprising a grid opening (115) defined by a pair of adjacent tracks (110a, 110b) of the first set of tracks (110) and a pair of adjacent tracks (111a, 111b) of the second set of tracks (111); a plurality of storage columns (105) located beneath the track system (108), wherein each storage column (105) is located vertically below a grid opening (115) and arranged to store a stack (107) of storage containers (106); a container handling vehicle (3-5) for lifting at least one storage container (106) stacked in the stacks (107), the container handling vehicle (3-5) being configured to move laterally on the track system (108) above the storage columns (105) to access the storage containers (106) via the grid openings (115), wherein the container handling vehicle (3-5) comprises a lower part (17a) comprising at least one storage compartment (24) for storing a storage container (106), an upper part (17b) arranged vertically above the lower part (17a), a wheel assembly (18) for guiding the container handling vehicle (3-5) along the track system (108) and a power supply compartment (27a) for accommodating a replaceable power supply (28); a replaceable power supply (28) for accommodation in the power supply compartment, having a power supply charging connection (46); and a charging station (40) for charging of the replaceable power supply (28), the charging station (40) comprising a charging connection (45) configured to create an electrical connection with the power supply charging connection (46) and a power supply support (43) for releasably supporting the power supply (28) during charging; wherein the power supply compartment (27a) is arranged in the upper part (17b) of the container handling vehicle (3-5) and is configured to receive the replaceable power supply (28) via an opening facing towards the first direction (X) or the second direction (Y).
Patent WO-2019174942-A1 (WO)
Title: Breast shield arrangement for a breast pump
Inventor: KOSTER AAFJE GIJSBERTHA
IPC: A61M1/06
Filed: 2019-03-04
Abstract: A breast shield arrangement (300) for a breast pump comprises a first sealing portion (310), a port (320) and an intermediate portion (330) coupled between the first sealing portion (310) and the port (320). The intermediate portion (330) comprises a circumferentially extending wall defining a first volume (V1) which is adapted to receive a part of a breast, a first end (331), a curved portion (332) and a second end (333). The curved portion (332) comprises a second sealing portion (332c) which is adapted to at least partially seal the curved portion (332) against the nipple (310), the areola (320) or the breast (200) when a vacuum is applied at the port (320) creating a second volume (V2) between the first sealing portion (310, 332c) of the breast (200). The curved portion (332) at the second volume is curved outwardly as seen from the first sealing portion (310).
Patent WO-2019180077-A1 (WO)
Inventor: ANDERSEN HANNE
IPC: H01M10/0525
Filed: 2019-03-20
Abstract: The present application relates to a composition for electrochemical cells, wherein the composition comprises modified lignin and carboxymethyl cellulose. Preferably, said composition is a binder composition.The present application also relates to a negative electrode for an electrochemical cell, comprising said compositionaswell as a method for producing said negative electrode. The present invention also relates to the use of said composition as binder in a negative electrode, respectively, asdispersant used during the manufacturing thereof.
Patent WO-2019206590-A1 (WO)
Title: A clamp
Inventor: SILLITOE CHRIS
IPC: F16L23/04
Filed: 2019-04-03
Abstract: A clamp (2) comprising: a first arcuate portion (4a); a second arcuate portion (4b) connected to the first arcuate portion via a hinge; and a ratchet mechanism for locking the first and second arcuate portions in a closed position; wherein the first and second arcuate portions each comprise a circumferential groove (16a, 16b) which tapers in a radial direction from an opening of the groove to a base of the groove; wherein the groove of one of the first and second arcuate portions (4a, 4b) has an angular extent which exceeds 180 degrees and has an opening with a width w1, w2, w3 which is narrower at opposing ends of the groove than at a position partway between the ends.
Patent WO-2019202018-A1 (WO)
Inventor: NIERHOFF DANIEL
IPC: B62D35/02
Filed: 2019-04-17
Abstract: L'invention concerne un dispositif anti-encastrement (2) conçu pour un ensemble batterie de véhicule (1), caractérisé en ce que ce dispositif anti-encastrement (2) comprend au moins une première pièce de dispositif anti-encastrement (10) et une deuxième pièce de dispositif anti-encastrement (20), la première pièce de dispositif anti-encastrement (10) présentant une première zone plane (11) et une zone de support (12), ladite première zone plane (11) comportant un plan longitudinal principal (100) et la zone de support (12) s'étendant dans la direction d'une normale à la surface (200) du plan longitudinal principal (100), la première et la deuxième pièce de dispositif anti-encastrement (10, 20) étant au moins partiellement adjacentes et/ou présentant une zone de chevauchement (30).
Patent WO-2019228899-A1 (WO)
Inventor: SIMMENDINGER ROLAND
IPC: D04B15/14
Filed: 2019-05-23
Abstract: The invention relates to a braking element (100) for braking a knitting element movement in a guide channel, the braking element (100) having at least one connecting portion (102, 104) and at least one braking portion, wherein the at least one connecting portion (102, 104) is displaceable between an assembly/disassembly position and a holding position, the braking element (100) has at least one spring portion (108), and the at least one spring portion (108) subjects the at least one connecting portion (102, 104) to a spring force in the direction of the holding position, and relates to a knitting element, a knitting element carrier, a knitting device, and a modular system for a knitting device having at least one such braking element (100).
Patent WO-2019234085-A1 (WO)
Title: Electroless copper or copper alloy plating bath and method for plating
Inventor: KULKO ROMAN-DAVID
IPC: C23C18/48
Filed: 2019-06-05
Abstract: An electroless copper plating bath for depositing a copper or copper alloy layer on a surface of a substrate, comprising a) copper ions; b) at least one reducing agent suitable for reducing copper ions to metallic copper; c) at least one complexing agent for copper ions; characterized in that the electroless copper plating bath further comprises d) at least one compound according to formula (1) wherein Z1 and Z2 are independently selected from the group consisting of hydrogen; carboxylic acid group; carboxylate group; sulfonic acid group; sulfonate group; carboxamide group; nitrile group; nitro group; substituted or non-substituted trialkylammonium group; substituted or non-substituted 2-carboxyvinyl group; substituted or non-substituted 2-vinylcarboxylate group; substituted or non-substituted 2-(trialkylammonium)vinyl group; substituted or non-substituted hydroxamic acid group; and substituted or non-substituted oxime group; with the proviso that at least one of Z 1  and Z 2  is not hydrogen; and wherein R 1 , R 2 , R 3  and R 4  are defined as follows: i. R 1 , R 2 , R 3  and R 4  are hydrogen; or ii. R 1  with R 2  are forming together a substituted or non-substituted aromatic ring moiety, R 3  and R 4  are hydrogen; or iii. R 3  with R 4  are forming together a substituted or non-substituted aromatic ring moiety, R 1  and R 2  are hydrogen; or 25 iv. R1 with R2 as well as R 3  with R 4  are forming together a substituted or non- substituted aromatic ring moiety, respectively. The invention further concerns a method for depositing at least a copper or copper alloy layer on a surface of a substrate, a layer system and a kit-of-parts for providing the inventive electroless copper plating bath.
Patent WO-2019238828-A1 (WO)
Title: Selection system for evolving proteases and protease-cleavage sites
Inventor: VERA RODRIGUEZ ARTURO
IPC: C12N9/12
Filed: 2019-06-13
Abstract: The present invention relates to a fusion protein, comprising the structure N- PCS Y  - degSig N  - M - PCS X  - degSig C  -C; wherein N represents the N-terminus; PCS Y  and PCS X  each represent a protease cleavage site (PCS), which differ from each other in at least one amino acid residue; degSig N  represents a degradation signal which promotes degradation of the fusion protein in a host cell if PCS Y  is cleaved by a protease such that the first amino acid of degSig N  becomes the new N-terminus of the remaining fusion; M represents a cytoplasmic selection marker; and degSig C  represents a second degradation signal which promotes degradation of the fusion protein in a host cell if PCS X  is not cleaved by a protease; and C represents the C-terminus. Further provided is a nucleic acid construct, comprising a nucleic acid sequence coding for said fusion protein, a nucleic acid expression construct library, comprising a plurality of such nucleic acid expression constructs in diversified form, and methods using the fusion protein and nucleic acid constructs coding therefor. Finally, the present invention provides variants of bdSUMO and bdSENP1 which have been identified by the methods of the present disclosure, and which exhibit improved properties over existing orthogonal protease/protease cleavage site-pairs which are currently used with wild-type bdSUMO and wildtype bdSENP1.
Patent WO-2020025456-A1 (WO)
Title: Brennstoffzellenstack und verfahren zum herstellen eines brennstoffzellenstacks
Inventor: WALD FELIX
IPC: H01M8/248
Filed: 2019-07-25
Abstract: Die vorliegende Erfindung betrifft einen Brennstoffzellenstack (10) und ein Verfahren zum Herstellen eines solchen Brennstoffzellenstacks (10). Der Brennstoffzellenstack (10) umfasst dabei wenigstens zwei Brennstoffzellenmodule (58) mit jeweils wenigstens zwei Einzelzellen (5), wobei jedes Brennstoffzellenmodul (58) Modulendplatten (70) an beiden Zellenstapelaußenseiten (66) aufweist,Stapelendplatten (78), welche an beiden Modulstapelaußenseiten (77) der aufeinandergestapelten Brennstoffzellenmodule (58) angeordnet sind, und Brennstoffzellenstackkompressionsmittel (82) über welche die aufeinandergestapelten Brennstoffzellenmodule (58) zu einem Brennstoffzellenstack (10) verspannt sind.