baber/WOPTO huggingface dataset:
Patent WO-2020198627-A1 (WO)
Inventor: YAN YUSHAN
IPC: B01D71/80
Filed: 2020-03-27
Abstract: Poly(aryl alkylene) polymers or poly(aryl-crown ether-alkylene) polymers with pendant cationic groups are provided which have an alkaline-stable cation, such as imidazolium, introduced into a rigid aromatic polymer backbone free of ether bonds. Hydroxide exchange membranes or hydroxide exchange ionomers formed from these polymers exhibit superior chemical stability, hydroxide conductivity, decreased water uptake, good solubility in selected solvents, and improved mechanical properties in an ambient dry state as compared to conventional hydroxide exchange membranes or ionomers. Hydroxide exchange membrane fuel cells and hydroxide exchange membrane electrolyzers comprising the poly(aryl aikylene) polymers or poly(aryl-crown ether-alkylene) polymers with pendant cationic groups exhibit enhanced performance and durability at relatively high temperatures.
Patent WO-2020219782-A1 (WO)
Inventor: NAM GINA WOO
IPC: A44C5/20
Filed: 2020-04-24
Abstract: The jewelry system of the present invention is used for easily layering jewelry by connecting strands of similar types of jewelry, such as necklace strands, into a layered jewelry piece (multi-strand necklace), and which prevents tangling and provides a distinctive presentation of each layer. The present invention allows for variety in the combining and re-arranging of individual strands in any desired order, by the use of end couplers on the ends of each strand and one or more connector pairs disposed on one or more of strands This allows for the creation of customized layered jewelry pieces that can be adjusted to suit a variety of styles. The design of the present invention allows for the use of singular strands to form into a layered jewelry piece that is distinctively presented in a symmetrical, cascading arrangement, which moves uniformly as one piece with the weight of gravity, virtually eliminating the risk of tangling. An additional purpose of this system is to have more versatility for the user' s jewelry and increase the convenience of wearing fully constructed, customizable, layered jewelry pieces which can be put on and removed as one piece.
Patent WO-2020227463-A1 (WO)
Inventor: MCALINDON TIMOTHY
IPC: A61B5/00
Filed: 2020-05-07
Abstract: Determining a composite score includes deriving, based on an image set that includes at least one three-dimensional image of the synovial joint, first and second information. The first information indicates cumulative damage to the synovial joint. The second information indicates either one or both joint pain and loss of function of the synovial joint. The resulting composite score provides an objective measure of joint damage or an extent of joint disease.
Patent WO-2020227503-A1 (WO)
Inventor: CHUMAKOV PETER M
IPC: A61K35/761
Filed: 2020-05-07
Abstract: Un système de support polyvalent pour l'administration systémique de virus oncolytiques comprend des cellules dendritiques ayant au moins un virus oncolytique chargé à l'intérieur de celles-ci. Selon la croyance, les cellules dendritiques protègent le ou les virus oncolytiques des anticorps neutralisants, peuvent transporter le ou les virus oncolytiques vers des emplacements de tumeur ciblés, puis délivrer des virions aux emplacements de tumeur.
Patent WO-2020251872-A1 (WO)
Title: Hydroxypyrrolidine-substituted arylsulfonamide compounds with selective activity in voltage-gated sodium channels
Inventor: ROECKER ANTHONY
IPC: C07D487/04
Filed: 2020-06-08
Abstract: Disclosed are compounds of Formula A, or a salt thereof: Wherein "A 1" , R 1 , R 2 , R 3 , R 6 , and R 7  are as defined herein, which compounds have properties for blocking Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula A or their salts, and methods of treating cough, itch and neuropathic pain disorders using the same.
Patent WO-2021126311-A1 (WO)
Title: Reinforcement learning system and method for generating a decision policy including failsafe
Inventor: MOORE KENNETH L
IPC: G06N7/00
Filed: 2020-06-30
Abstract: A reinforcement learning system produces a decision policy equipped with a Failsafe decision that is invoked when machine cognition, i.e., a computed environmental awareness known as belief, is untrustworthy. The system and policy are executed on a computer system. The policy can be used for autonomous decision making or as an aid to human decision making. Also presented is a method of tuning Failsafe to a desired level of acceptable trustworthiness.
Patent WO-2021003223-A1 (WO)
Inventor: JACKSON WESLEY M
IPC: A61K9/06
Filed: 2020-07-01
Abstract: The present disclosure is directed to peptide-polymer conjugates utilizing hydrophilic linkers, and their use in treating diseases or disorders. In one embodiment, the present invention provides a conjugate of Formula I: (X-Y)n-Z Formula (I) wherein each X is independently a peptide having a molecular weight of from about 5 kDa to about 200 kDa; each Y is independently a hydrophilic linker; Z is a biocompatible polymer having a molecular weight of from about 0.1 MDa to about 3 MDa; and subscript n is an integer from 10 to 1000.
Patent WO-2021007564-A1 (WO)
Inventor: BECKER MATTHEW
IPC: G02B6/44
Filed: 2020-07-10
Abstract: A unitube breakout kit includes a bottom portion extending from a neck end to an outlet end. A top portion is selectively attached to the bottom portion. The bottom portion and the top portion together define a central cavity configured to contain at least one of fiber optic fibers or ribbon fibers. The bottom portion defines a first pair of slots configured to cooperate with a fastener to attach at least one of fiber optic core tube or unitube ribbon cable to the bottom portion.
Patent WO-2021016430-A1 (WO)
Title: Stable compositions of mrna-loaded lipid nanoparticles and processes of making
Inventor: KARVE SHRIRANG
IPC: A61K48/00
Filed: 2020-07-23
Abstract: The present invention provides an improved compositions and processes for preparing mRNA-loaded lipid nanoparticles (mRNA-LNPs). In some embodiments, the present invention provides mRNA-LNPs with exceptional stability and is particularly useful in cases where LNPs comprising low or no PEG-modified lipids are desired.
Patent WO-2021035180-A1 (WO)
Title: Cleavage of single stranded dna having a modified nucleotide
Inventor: GARDNER ANDREW
IPC: C12Q1/6806
Filed: 2020-08-21
Abstract: Methods are provided that, for example, include (a) combining ssDNA containing a modified nucleotide (e.g., a ssDNA with a modified nucleotide proximate to its 5'end) with a DNA cleavage enzyme capable of cleaving the ssDNA at the modified nucleotide (e.g., to generate a first ssDNA fragment having a 3'OΗ and a second ssDNA fragment having the modified nucleotide); wherein the ratio of enzyme to DNA substrate is less than 1:1 molar ratio (m/m); and (b) cleaving at least 95% of the ssDNA at the modified nucleotide. In some embodiments, a method may comprise (a) combining (i) a ssDNA comprising a modified nucleotide (e.g., proximate to its 5'end) with (ii) a DNA cleavage enzyme capable of cleaving the ssDNA at the modified nucleotide (e.g., to generate (after cleavage) a first ssDNA fragment having a 3'OΗ and a second ssDNA fragment comprising the modified nucleotide) wherein the ratio of enzyme to DNA substrate is less than 1:1 molar ratio and cleaving at least 95% of the ssDNA at the modified nucleotide. In some embodiments, methods provided herein may include (a) combining (i) a ssDNA (1) immobilized on a substrate and (2) comprising a modified nucleotide with (ii) a ssDNA cleaving enzyme capable of cleaving the ssDNA at the modified nucleotide (e.g., to generate (after cleavage) a first ssDNA fragment having a 3'OΗ and a second ssDNA fragment comprising the modified nucleotide); and (b) cleaving the immobilized ssDNA to release the second single stranded DNA fragment from the substrate. At least 95% (m/m) of an ssDNA comprising a modified nucleotide may be cleaved in less than 60 minutes.
Patent WO-2021055150-A1 (WO)
Title: Rocker assembly with a hydraulic lash adjuster
Inventor: HATTIANGADI ASHWIN A
IPC: F01L1/24
Filed: 2020-08-27
Abstract: A rocker assembly including a rocker shaft having an outer surface, main oil passage, a first radial passage and a second radial and a rocker arm having a first end and an inner cylindrical surface defining a bore, wherein the rocker shaft is received in the bore to pivotably mount the rocker arm onto the rocker shaft. The rocker arm includes a hydraulic lash adjuster mounted within the first end and a first oil passage having an inlet at the inner cylindrical surface and an outlet in fluid communication with the hydraulic lash adjuster. The inner cylindrical surface is spaced apart from the outer surface of the rocker shaft by a radial clearance, and wherein an inlet to the first oil passage and a first outlet of the first radial passage are in a loaded region of the radial clearance.
Patent WO-2022046102-A1 (WO)
Title: Method of bounding spatial data
Inventor: FIT ANDREW
IPC: G06T17/00
Filed: 2020-08-31
Abstract: A computer implemented method of bounding spatial data associated with the geometric bounds of an item mapped into one or more 3-D axis-aligned bounding boxes is disclosed. The geometric bounds bound each permutation of all possible positions of the item geometrically. The method comprises firstly partitioning a set of bounding boxes using a first group of intervals along the  x  axis direction and allocating a partition identification  xpa r. Secondly partitioning the set of bounding boxes using a second group of intervals along the  y axis  direction and allocating a partition identification  ypar  is carried out. Thirdly, partitioning the set of bounding boxes using a third group of intervals along the  z  axis direction and allocating a partition identification  zpar  is carried out. The set of bounding boxes is then partitioned by partition identification tuples ( xpar, ypar, zpar ). Preferably bounding boxes with the same partition identification tuple are then merged.
Patent WO-2021042043-A1 (WO)
Title: Hydrogels utilisés comme formes galéniques à administrer par voie orale, leurs procédés de préparation et leurs méthodes d'utilisation
Inventor: GODFRIN PAUL DOUGLAS
IPC: C08F220/14
Filed: 2020-08-31
Abstract: L'invention concerne un procédé de fabrication, et l'utilisation d'hydrogels polymères réticulés en tant que formes galéniques finales pour l'administration par voie orale de composés ayant une valeur nutritionnelle et/ou thérapeutique, y compris, mais de façon non limitative, des suppléments, des thérapies à base de cellules et des principes pharmaceutiques actifs.
Patent WO-2021055480-A1 (WO)
Title: System and method for social networking among users of a reusable item
Inventor: PARK JANE
IPC: G06Q10/00
Filed: 2020-09-16
Abstract: A system and method are provided for social networking among users of reusable items, such as a reusable gift wrap assembly. The system can include an application that runs on a mobile device that enables users to create and share digital messages for the recipient of the gift. The gift wrap assembly can include a reusable wrap and a reusable band for binding the wrap about the gift. The gift wrap assembly includes a unique identifier that is recognizable by the system. In this manner, the system can track the gift wrap as it travels among users, thereby creating a social network connection between users that have interacted with the gift wrap assembly.
Patent WO-2021071725-A1 (WO)
Title: Default quasi-colocation for single downlink control information-based multiple transmission reception points
Inventor: KHOSHNEVISAN MOSTAFA
IPC: H04L5/00
Filed: 2020-09-30
Abstract: Methods, systems, and devices for wireless communications are described. A communication device, which may be otherwise known as user equipment (UE) may receive a downlink control information (DCI) on a physical downlink control channel (PDCCH). The DCI may include one or more of an indication of a set of transmission configuration indicator (TCI) states related to a physical downlink shared channel (PDSCH), one or more receive beams associated with the set of TCI states, or a physical downlink shared channel (PDSCH) scheme. The UE may decode the DCI and may determine a temporal period associated with the indication of the set of TCI states. The UE may receive, based on the temporal period, the PDSCH according to one or more of the set of TCI states, the one or more receive beams associated with the set of TCI states, the PDSCH scheme, or one or more default receive beams.
Patent WO-2021086541-A1 (WO)
Inventor: GUO YINZHONG
IPC: C08G18/65
Filed: 2020-10-01
Abstract: A polyolefin-based laminating adhesive composition for use in producing a mechanical recyclable material, the adhesive composition including a mixture of: (a) at least one saturated polyolefin polyol; and (b) at least one aliphatic multi-functional isocyanate compound; a process for producing the above adhesive composition; a mechanically recyclable multi-layer laminate including: (A) at least one first film substrate layer; (B) at least one second film substrate layer; and (C) at least one layer of the above polyolefin-based laminating adhesive composition; wherein the at least one first film substrate layer is bonded to the at least one second film substrate layer via the adhesive composition layer; a process for producing the above mechanically recyclable multi-layer laminate; and a packaging article made from the above mechanically recyclable multi-layer laminate.
Patent WO-2021101632-A1 (WO)
Inventor: BEKIYANTS SERGEY
IPC: G06F3/02
Filed: 2020-10-02
Abstract: A system for decentralized private blockchains network is provided. In some implementations, the system performs operations comprising receiving, at a client system, data having a sensitivity level, the operations further comprise splitting, at the client system, the data based on the sensitivity level, the splitting comprising splitting the data into data portions. The operations further comprise storing, at a decentralized storage system, the decentralized storage system comprising a plurality of private blockchains, each of the data portions in a separate private blockchain of the plurality of private blockchains. The operations further comprise storing, at a multi-decentralized private blockchains network (MDDV), pointers to locations of the data portions within the decentralized storage system. Related systems, methods, and articles of manufacture are also described.
Patent WO-2021076850-A1 (WO)
Title: Desalination using pressure vessels
Inventor: RAMAMURTHY SHANKAR
IPC: C02F1/44
Filed: 2020-10-16
Abstract: Disclosed techniques include desalination using pressure vessels. Access to a set of at least three pressure vessels is obtained. The pressure vessels are interconnected using piping and computer-controlled switching valves. A first pressure vessel of the set is filled with a prepurified liquid. A second pressure vessel of the set is filled with a pressurized gas. The pressurized gas is sharp interface immiscible with the prepurified liquid. The switching valves are controlled to enable the pressurized gas in the second pressure vessel to force the prepurified liquid from the first pressure vessel into a reverse osmosis chamber. The switching valves are controlled to enable a third pressure vessel of the set to fill with additional prepurified liquid. The switching valves are controlled to enable the pressurized gas that entered the first pressure vessel to force the additional prepurified liquid from the third pressure vessel into the reverse osmosis chamber.
Patent WO-2021080996-A1 (WO)
Title: Auto-indexing lance positioner apparatus and system
Inventor: SCHNEIDER JOSEPH A
IPC: B08B9/032
Filed: 2020-10-20
Abstract: A system and an apparatus for positioning a plurality of flexible cleaning lances through tubes penetrating a tube sheet of a heat exchanger tube sheet, includes a smart lance tractor drive, a controller, and a tumble box connected to the controller operable to generate and/or distribute electrical power to the AC induction sensor from an air pressure source, supply electrical power to the controller and distribute pneumatic power to pneumatic motors for positioning the tractor drive on the positioner frame. The smart tractor drive includes sensors for detection of mismatch between expected and actual lance positions, sense lance insertion distance and lance removal and provide automated drive reversal operation to remove blockages within tubes being cleaned.
Patent WO-2021118740-A1 (WO)
Inventor: UDAGAVE SHITAL SAWANTA
IPC: H01P1/18
Filed: 2020-11-11
Abstract: A first mechanical linkage is connected between a RET actuator and a first phase shifter. A second mechanical linkage is connected between the RET actuator and a second phase shifter. The RET actuator includes a rotary drive element operably coupled to at least one drive gear for moving the at least one drive gear in a first rotary direction and a second rotary direction. A first drive system is connected to the first mechanical linkage and a second drive system is connected to the second mechanical linkage. The first drive system has a first driven gear and the second drive system has a second driven gear where the first driven gear and the second driven gear are coaxially located relative to one another. An index system selectively couples the at least a one drive gear to one of the first driven gear and the second driven gear.
Patent WO-2021113073-A1 (WO)
Inventor: HANKINS JOHN
IPC: A42B1/04
Filed: 2020-11-17
Abstract: A system for communicating pitch selections wirelessly from a wireless transmitter has a coded signal generator that generates coded signals in accordance with selected pitch types. A receiver decodes the received coded signals, selects an audio file based on the received coded signal and generates an audio signal announcing the selected pitch type based on the transmitted selected pitch type in accordance with the received coded signal. The audio signal is transduced by a bone conductor transducer so that the player can hear the announced selected pitch type through bone conduction.
Patent WO-2021108779-A1 (WO)
Title: Détecteur de gaz pour masque facial
Inventor: KACHIKIAN KEVIN
IPC: A62B18/08
Filed: 2020-11-27
Abstract: L'invention concerne un système de masque facial permettant de détecter des gaz et des composés organiques volatils (COV). Le système de masque facial comprend un masque de protection, au moins un dispositif de communication, un dispositif de détection de gaz et un capteur externe. Le dispositif de détection de gaz comprend une unité d'alimentation en énergie, une boucle de bobine inductive, un microdispositif de commande interne, une puce de communication sans fil et un capteur interne. Le capteur interne est configuré pour détecter et mesurer une pluralité de lectures de COV à l'intérieur du masque. Le capteur externe est configuré pour détecter et mesurer une pluralité de lectures de COV à l'extérieur du masque. Le capteur externe compare une valeur de COV interne moyenne avec une valeur de COV externe moyenne pour fournir des informations uniques et précises de l'environnement à l'intérieur du masque de protection, en protégeant ainsi l'utilisateur contre des situations dangereuses.
Patent WO-2021113667-A1 (WO)
Inventor: DENU JOHN
IPC: C07D209/48
Filed: 2020-12-04
Abstract: The present disclosure provides compounds according to Formula I and pharmaceutically acceptable salts thereof, as well as compositions including such compounds and a pharmaceutically acceptable carrier or excipient. Further provided are methods of inactivating SIRT6 with compounds of Formula I as well as compounds of Formula III, W 2 -R 2 -Y-R 3 , as described herein. In addition, the present technology provides methods of treatment using such compounds to lower LDL levels, lower triglyceride levels, and/or increase glucose tolerance in a subject, and/or to inhibit proliferation of ovarian, colorectal, hepatocellular, non-small cell lung, glioblastoma, osteosarcoma, pancreatic, and skin cancer cells, and/or inhibit liver and/or kidney fibrosis, and/or promote corneal epithelial wound healing.
Patent WO-2021118946-A1 (WO)
Inventor: JANCOVICH BENJAMIN ALEXANDER
IPC: H03G9/00
Filed: 2020-12-08
Abstract: Some noise compensation methods involve receiving microphone signals corresponding to ambient noise from a noise source location in or near an audio environment, determining or estimating a listener position in the audio environment and estimating at least one critical distance, which is a distance from the noise source location at which directly propagated sound pressure is equal to diffuse field sound pressure. Some examples involve estimating whether the listener position is within the at least one critical distance and implementing a noise compensation method for the ambient noise based, at least in part, on an estimate of whether the listener position is within the critical distance.
Patent WO-2021126936-A1 (WO)
Title: Process for treating polyester methanolysis depolymerization product streams
Inventor: KETCHIE WILLIAM
IPC: C08J11/24
Filed: 2020-12-16
Abstract: Disclosed is a method for treating the product stream from a polyester methanolysis depolymerization process wherein the product stream includes dimethyl terephthalate and one or more side species selected from the group consisting of dimethyl phthalate, dimethyl isophthalate, bisphenol-A, an adipic acid diester and colorants. The method includes a) hydrogenating said dimethyl terephthalate to form one or more of dimethyl 1,4- cyclohexanedicarboxylate and 1,4-cyclohexanedimethanol; and (b) hydrogenating one or more of said one or more side species of said product stream. A method for depolymerization of polyester is also described.
Patent WO-2021138620-A1 (WO)
Title: Media platform for exercise systems and methods
Inventor: DEGOOYER PAUL
IPC: G06F16/735
Filed: 2020-12-31
Abstract: Systems and methods for delivering exercise content to a user of an exercise apparatus include a database storing exercise content, data associated with a content provider and data associated with an application provider, and a platform server operable to facilitate delivery of the exercise content to the exercise apparatus. The platform server delivers for display on the exercise apparatus archived exercise classes for selection by the user, receives from the exercise apparatus a selection, transmits data representing content of the selected archived exercise class, receives performance data from the exercise apparatus based on activity by the user, and generates archived performance data representing archived user performance parameters for a plurality of other users over at least the portion of the selected archived exercise class. Data is synchronized and updated for display by the exercise apparatus to simulate the user competing with at least some of the other users.
Patent WO-2021026546-A1 (WO)
Inventor: CHIAO JERRY
IPC: B25H3/06
Filed: 2020-05-28
Abstract: A workbench has a frame disposed on a set of wheels with a plurality of storage solutions, such as drawers, disposed within the frame. The workbench can include a work surface on a top surface of the frame and one or more handles permitting movement of the workbench as desired. The workbench can include a pegboard surface that is pivotable between a deployed configuration, where the pegboard extends upward from a back surface of the workbench, and a stowed configuration, where the pegboard is stored adjacent the back surface of the workbench. Typically, in the stowed configuration, the pegboard surface does not extend beyond either a plane defined by the work surface or a plane defined by a bottom surface, opposite the work surface, of the workbench frame. The workbench may be packaged and shipped in the stowed configuration, allowing the user to easily fully assembly the workbench assembly.