baber/WOPTO huggingface dataset:
Patent NZ-602206-A (NZ)
Title: Adjustable carriage
Inventor: JABER HANI
IPC: E05D13/00
Filed: 2011-02-17
Abstract: 602206 An adjustable carriage (1) suitable for use with sliding doors and windows is disclosed. Sliding doors are generally provided with an assembly with rolling wheels (17) at the bottom of a door. The rolling wheels which are generally located within an aluminium extrusion provided at the bottom of the door may be arranged to roll along a trackway provided on the floor so that the door may be slid sideways. However, as the walls and floors of buildings are not as a general rule perfectly aligned, and dimensional sizing is sometimes inaccurate, there needs to be some capacity in the rolling wheel assembly to overcome the difficulties such imperfections in buildings provide. The adjustable carriage has an elongate housing having a cavity in which first (5) and second (5) slidable members reside. A displacement means (31) is adapted to exert pressure against at least one of the slidable members to cause them to change their height within the cavity with respect to the bottom edge. The slidable members also slide vertically independently of each other so that variations in the trackway are accommodated for.
Patent NZ-604079-A (NZ)
Title: Safety device for a pre-filled syringe and injection device
Inventor: ROBERTS GARETH
IPC: A61M5/32
Filed: 2011-06-21
Abstract: 604079 A safety device (1) for a pre-filled syringe (2) comprises a hollow support body (1.2) having a releasable mounting means (1.2.6) adapted to mount a pre-filled syringe within the support body, a hollow outer body (1.3) sildably arranged with respect to the support body and adapted to receive the support body and a release collar (1.4) non-rotatably arranged within the support body. The release collar is movable relative to the support body and adapted to release the mounting means. A guide track (1.2.4) is formed into at least one substantially planar side wall (1.2.1 ) of the support body. The release collar comprises at least one flexible arm (1.4.5) with a guide pin (1.4.6) that extends from the flexible arm and protrudes through the guide track. The guide pin is movable within and along the guide track in a plane defined by the substantially planar side wall. A guide rail (1.3.5) is formed into at least one substantially planar inner surface of the outer body. The guide rail is adapted to abut against the guide pin to guide the movement of the guide pin along the guide track when the outer body is slid relative to the support body.
Patent NZ-604877-A (NZ)
Title: Improved recombinant human follicle-stimulating hormone
Inventor: GOLETZ STEFFEN
IPC: A61K38/24
Filed: 2011-08-04
Abstract: 604877 Disclosed is a recombinant FSH preparation, wherein the recombinant FSH in the preparation has a glycosylation pattern comprising the following characteristics: (i) a relative amount of glycans carrying bisecting N-acetylglucosamine (bisGlcNAc) of at least 20 % of the total amount of glycans attached to FSH in the preparation; and (ii) a relative amount of 2,6-coupled sialic acid of at least 40% of the total amount of sialic acids. Further disclosed is a recombinant FSH preparation obtained by production in the human cell line GT-5s or a cell line derived therefrom or a cell line homologous thereto.
Patent NZ-610143-A (NZ)
Title: Hybrid molecules containing pharmacophores of fluconazole as antifungal agents and their preparation
Inventor: BORATE HANUMANT BAPURAO
IPC: C07D409/12
Filed: 2012-04-04
Abstract: Disclosed herein are antifungal compounds of general Formula 1, wherein the substituents are as defined in the specification, which contain fluconazole pharmacophore moieties coupled with other moieties including aryl enones and chalcones. Also disclosed are methods for preparing compounds of Formula 1 and pharmaceutical preparations containing compounds of Formula 1 for prevention and treatment of fungal infections. Examples of a compound of Formula 1 are: (E)-1-(4-(2-(2,4-Difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propoxy)phenyl)-3-phenylprop-2-en-1-one (E)-1-(4-(2-(2,4-Difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propoxy)pheny 1)-3-(4-methoxyphenyl)prop-2-en-1-one S-(+)-(E)-3-(4-chlorophenyl)-1-(4-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propoxy)phenyl)prop-2-en-1-one
Patent NZ-611365-A (NZ)
Title: Fused aminodihydrothiazine derivatives useful as bace inhibitors
Inventor: HALL ADRIAN
IPC: C07D513/04
Filed: 2012-01-20
Abstract: Disclosed are fused aminodihydrothiazine derivatives of formula (I): wherein X is hydrogen or fluorine; A is CH or N; Y is methyl, ethyl, monofluoromethyl, difluoromethyl, trifluoromethyl, difluoroethyl, methoxy, ethoxy, methoxymethyl or cyano; and pharmaceutically acceptable salts thereof; which compound has an Aβ production inhibitory effect or a BACE1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Aβ and typified by Alzheimer-type dementia. Examples of compounds of formula (I) are: N-(3-((4aS,5S,7aS)-2-amino-5-(trifluoromethyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl)-5-cyanopicolinamide; N-(3-((4aS,5S,7aS)-2-amino-5-(trifluoromethyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d] [1,3]thiazin-7a-yl)-4-fluorophenyl)-5-(difluoromethyl)pyrazine-2-carboxamide and N-(3-((4aS,5S,7aS)-2-amino-5-(trifluoromethyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide.
Patent NZ-622581-A (NZ)
Title: Straightening apparatus
Inventor: MEYER CHARLES RUDOLPH
IPC: C25C7/02
Filed: 2012-08-20
Abstract: An anode straightening apparatus (see 10, figure 1), for the straightening of an anode (100) typically used in an electrowinning process is disclosed. The apparatus includes at least one clamp (21.1, 21.2) for clamping the anode to the apparatus during the course of the straightening process. At least one sensor (see 29.1, 29.2 & 29.3, figure 5) monitors the curvature of the blade (102) of the anode (100) when the anode is secured to the apparatus by the clamps. A movable head (24) houses straightening means, such as rollers (see 25.1 & 25.2, figure 5), for bending the anode in a desired direction in response to feedback received from the sensor. The head is movable in two planes of movement which are transverse to one another. The apparatus further has actuators (27.1, 27.2, 28.1, 28.2) for urging the straightening means along its axes of movement in the vertical (26.1) and horizontal (26.2) planes respectively so that the anode may be straightened by urging the straightening means in the second plane of movement while moving it in the first plane of movement. A method of straightening an anode (100) is also disclosed.
Patent NZ-625745-A (NZ)
Title: Fgfr antibody drug conjugates (adcs) and the use thereof
Inventor: LERCHEN HANS-GEORG
IPC: C07K4/00
Filed: 2012-12-12
Abstract: Disclosed are antibody-linked auristatin conjugates of the general formula (Ia) which comprise a novel linker, wherein AK is a binder which is an antibody or an antigen-binding antibody fragment that binds to FGFR2, and wherein the linker comprises the group L2 which is a linear C2-C10alkylene-##4 group, or a polyethylene linking group of the formula ##3-CH2-CH2-[O-CH2-CH2-]p-##4; p is a number from 2 to 6; ##3 marks the linkage site on the side with AK; ##4 marks the bond to the nitrogen atom of the auristatin derivative, and wherein the C2-C10alkylene group is optionally substituted by 1 to 4 substituents selected independently of one another from the group consisting of methyl, hydroxyl, and benzyl, or wherein two carbon atoms of the C2-C10alkylene group in 1,2-, 1,3- or 1,4-relation to one another, with inclusion of any carbon atoms situated between them, are optionally bridged to form a cycloalkyl ring or a phenyl ring; for the treatment and/or prophylaxis of hyperproliferative and/or angiogenic diseases. In a preferred embodiment L2 is an unsubstituted pentylene chain linked to AK through a carbonyl group.
Patent NZ-627450-A (NZ)
Title: Stimulation of ovarian follicle development and oocyte maturation
Inventor: CHENG YUAN
IPC: C12N5/00
Filed: 2012-12-14
Abstract: Methods are disclosed for promoting development of a mature oocyte, comprising transiently contacting ovarian tissue with a C-type natriuretic peptide and/or an R-spondin, or fusion proteins thereof, in a dose effective to promote development of a mature oocyte
Patent NZ-701906-A (NZ)
Title: Method for separating portions of a food mass
Inventor: ZEUSCHNER ROLAND
IPC: B65B61/18
Filed: 2013-06-05
Abstract: The present invention relates to a method and device for or separating portions of a food mass (3) from a film tube (1), which is continuously advanced along a tube-conveying path (9) on a conveyor belt having a continuous belt-running speed. The invention addresses the problem of creating greater flexibility in the transverse displacement of a food mass to produce variable packaging sizes of a food mass using the same displacement tool. The invention proposes that displacement rollers are driven by means of a drive, which is controllable in terms of the running thereof in a manner decoupled from the belt-running speed of a continuously running conveyor belt.
Patent NZ-703444-A (NZ)
Title: An airless tyre for vehicles
Inventor: LABUSCHAGNE PIETER JOHANNES
IPC: B60C7/10
Filed: 2012-05-24
Abstract: A non-inflatable vehicle tyre (1) comprising a rubber carcass (3) moulded to fit and be secured to a wheel rim (2) with a series of equally spaced passages (9) extending transversely through the carcass (3) to provide resilient supporting ribs ( SO) between the passages (9) and having a road engaging tread (5A) moulded to the carcass (3) over a band of flexible steel cord (4A) reinforcing in which the band comprises a plurality of superimposed plies of coated hard steel cord (4A) and in which minor passages (9 A) arc provided through the ribs (10).
Patent NZ-705358-A (NZ)
Title: A method for selection of agents influencing intestinal motility disorders and pain
Inventor: CONNOLLY EAMONN
IPC: A23L33/135
Filed: 2013-09-03
Abstract: A method is provided for evaluating agents for the treatment of different intestinal motility disorders, using distinct methodological parts related to musculature and nerves of the GI tract which communicate with the brain. In particular, the present invention provides a method for the selection of an agent effective for the treatment of an intestinal motility disorder, wherein said method comprises: a) a step of spatiotemporal (ST) mapping carried out on a gastrointestinal segment to analyse the effect of said agent on gastrointestinal motility; and b) a step of ex vivo nerve bundle recording carried out on a gastrointestinal segment to analyse the effect of said agent on mesenteric afferent nerve firing. Bacterial strains selected by the methods of the invention and the use of said bacterial strains in the treatment of intestinal motility disorders are also provided.
Patent NZ-708037-A (NZ)
Title: Subsea processor for underwater drilling operations
Inventor: PEREIRA LUIS
IPC: H02J50/10
Filed: 2013-10-16
Abstract: Conventional blow-out preventers (BOP) are generally limited in operational capability and operate based on hydraulics. A BOP may be improved by having a subsea processing unit located underwater with the blow-out preventer. A system comprises one or more processor units, each comprising: a housing; a processor disposed within the housing; and an inductive power receiving device coupled to the processor and disposed within the housing, the inductive power receiving device configured to receive power for the processor through the housing; an underwater drilling component comprising: one or more receptacles, each: configured to removably receive a respective one of the one or more processor units; including an inductive power transmitting device configured to transfer power to the inductive power receiving device of the respective processor unit; and positioned on the underwater drilling component to permit coupling of the respective processor unit to the receptacle from an exterior of the underwater drilling component; and at least one sensor; and a wireless communications system configured to enable communication between the at least one sensor and at least one of the one or more processor units; wherein at least one of the one or more processor unites is configured to control the underwater drilling component based, at least in part, on data generated by the at least one sensor.
Patent NZ-712718-A (NZ)
Title: Channel inductor
Inventor: SETARGEW NEGA
IPC: H05B6/00
Filed: 2014-03-06
Abstract: A channel inductor of a channel induction furnace, the channel inductor comprising (a) a channel liner and (b) a back-up liner that supports the channel liner such that the integrity of the channel liner is not compromised during heat-up, dry-out, or operation of the channel induction furnace.
Patent NZ-713487-A (NZ)
Title: Pharmaceutical composites of poorly water soluble drugs and polymers
Inventor: GATTI PAOLO
IPC: A61K31/44
Filed: 2011-12-22
Abstract: Disclosed herein is a process for the preparation of a composite comprising at least one poorly soluble drug of Class II according to Biopharmaceutics Classification System (BCS) having low solubility and high gastrointestinal permeability, at least one polymeric carrier selected from the group consisting of cross-linked polyvinylpyrrolidone, crosslinked sodium carboxymethylcellulose, cross-linked cyclodextrins, cross-linked dextran, cross-linked starch, cross-linked methylcellulose and at least one not chemically cross-linked polymer, which is both soluble in water and organic solvent selected from the group consisting of hydroxypropylcellulose, hydroxyethylcellulose, hydroxypropylmethylcellulose, hydroxypropylmethycellulose acetate succinate, cellulose acetate trimellitate, acrylic and methacrylic polymers and their copolymers, methacrylic acid-methylmethacrylate copolymer, polyaminoalkyl methacrylate-methacrylic esters copolymer, dimethylaminoethyl methacrylate-butylmethacrylate-methylmethacrylate copolymer, vinylpyrrolidone-vinyl acetate copolymer, methylvinylether-maleic acid copolymer, polyethyleneglycol- caprolactame- vinylpyrrolidone copolymer, comprising the following steps: (1) Dissolving at least one poorly water soluble drug in a process solvent or process solvent mixture, wherein the solvent may is selected from methanol, ethanol, higher alcohols, acetone, chlorinated solvents, formamide, dimethylformamide, fluorinated hydrocarbons or mixture thereof; (2) Dissolving at least one not cross-linked polymer, which is both water and organic solvent soluble, into the drug solution of step (1); (3) Swelling at least one polymeric carrier with the solution prepared in step (2), thus obtaining a swollen composite; (4) Removing the process solvent from the swollen composite of step (3), wherein step (4) is carried out for a period of time which is equal or shorter than about 410 minutes and at a temperature from 35 to 60°C and wherein the process solvent is able to swell the polymeric carrier or to be absorbed by the polymeric carrier and to dissolve the poorly soluble drug and the water and organic solvent soluble not chemically cross-linked polymer.
Patent NZ-717641-A (NZ)
Title: Combination of an oxidant and a photoactivator for the healing of wounds
Inventor: BELLINI FRANCESCO
IPC: A61P17/02
Filed: 2009-11-06
Abstract: Disclosed herein is a method for wound healing which comprises the steps of: (a) topically applying on a non-human animal’s skin a composition comprising at least one oxidant, wherein the at least one oxidant is chosen from hydrogen peroxide, carbamide peroxide and benzoyl peroxide, and at least one photoactivator capable of activating the oxidant, wherein the at least one photoactivator is eosin; and (b) exposing said skin of step (a) to actinic light for a time sufficient for said photoactivator to cause activation of said oxidant. Said composition may further comprise a hydrophilic gelling agent selected from glucose, modified starch, methyl cellulose, carboxymethyl cellulose, propyl cellulose, hydroxypropyl cellulose, carbopol polymers, alginic acid, sodium alginate, potassium alginate, ammonium alginate, calcium alginate, agar, carrageenan, locust bean gum, pectin, and gelatin.
Patent NZ-721520-A (NZ)
Title: Novel 6-fused heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
Inventor: GUO LEI
IPC: C07D513/04
Filed: 2015-03-04
Abstract: The invention provides novel compounds having the general formula (I): wherein R1, R2, R3, R4, R5, R6, X, Y, W and n are as described herein, compositions including the compounds and methods of using the compounds. These compounds useful for therapy and/or prophylaxis in a human, and in particular to Hepatitis B virus (HBV) inhibitors by targeting on HBV capsid for the treatment of HBV infection.
Patent NZ-727154-A (NZ)
Title: Machine for sorting a mixture of waste, and associated sorting method
Inventor: CHARREYRE FABIEN
IPC: B07B1/22
Filed: 2015-05-22
Abstract: The invention relates to a rotary machine (1) for sorting a mixture of waste (2), said sorting machine (1) being characterized in that it comprises at least: a first trommel section (3) provided with a first separating wall (5), extending along a first length (L1), for separating the mixture of waste (2) into a first fraction of waste (13) that passes said first separating wall (5) and into a second, residual fraction of waste (14), and a second trommel section (4) provided with a second separating wall (6), extending along a second length (L2) less than the first length (L1), for separating the second, residual fraction of waste (14) into a sub-fraction of small waste (15) that passes said second separating wall (6), and into a sub-fraction of residual large waste (16). The machine allows for the sorting of dissimilar waste
Patent NZ-727701-A (NZ)
Title: Platinum compounds, compositions, and uses thereof
Inventor: SINGH SUKHJEET
IPC: C07F15/00
Filed: 2015-06-23
Abstract: The present teachings relate to compounds of Formula IIb and pharmaceutical compositions comprising the compound of Formula IIb for treatment of cancers. In some embodiments, the compound reacts with a functional group on a protein, engineered protein, antibody, antibody fragment, peptide, agonist, antagonist, aptamer or ligand which may be capable of recognizing a selected target cell population, and/or derivatives/analogs/mimics thereof.
Patent NZ-730359-A (NZ)
Title: Methods of treating and preventing staphylococcus aureus infections and associated conditions
Inventor: TORRES VICTOR
IPC: A61K39/395
Filed: 2012-06-19
Abstract: Discloses a composition comprising an isolated Leukocidin E (LukE) polypeptide fragment of SEQ ID NO: 11, wherein said LukE polypeptide fragment is 100-300 amino acids in length, and a pharmaceutically acceptable carrier.
Patent NZ-739570-A (NZ)
Title: Rubber teat element with flexible head geometry
Inventor: GRÜTER THOMAS
IPC: A01J5/08
Filed: 2016-07-12
Abstract: The invention relates to a rubber teat element (1) having a head part (2) and a shank part (3), which is connected to the head part (2). The head part (2) has a lateral surface (5) and an introduction opening (6) for an animal’s teat, wherein the introduction opening (6) is delimited by an inwardly oriented lip (4). The lateral surface (5) has at least one expansion region (7), which extends over at least part of a lateral-surface circumference (8) and at least part of a head-part length (9), wherein the lateral surface (5) is of undulating form, as seen in cross section, in the expansion region (7). The invention also relates to a teat cup and a milking cluster having a corresponding rubber teat element. The present invention provides a rubber teat element which, in particular in the case of small, thin and short animal teats, can be adapted to different teat geometries on account of the radial expansion capability of the head part.
Patent NZ-746013-A (NZ)
Title: Transparent modulatable kayak with shading system
Inventor: MAIONE ROBERTO
IPC: B63B17/02
Filed: 2017-03-08
Abstract: Transparent modulatable kayak with shading system characterized in that it is provided with two pairs of fitting devices (4), adapted to reversibly connect multiple kayaks; the tubular body (2.1) of the paddle (2) being reversibly divisible at the center; the inner volume of the hull (1) provided with a container (3.2) adapted to house a cloth (3) adapted to shade the user placed on the seat (1.3); said cloth (3) preferably having rectangular form and provided with at least four coupling devices (3.1) at the corners; the upper surface of the hull (1) being provided with a plurality of recesses (1.5), of which at least one pair is positioned at the bow (1.1) and at least one pair is positioned at the stern (1.2), each adapted to house a portion of the tubular body (2.1) of the paddle (2); said tubular body (2.1) being provided, at each end, with at least one coupling device (2.4) adapted to reversibly connect at least one of the corresponding coupling devices (3.1) of the cloth (3); said hull (1) being characterized in that it is made of any natural or synthetic polymer adapted to ensure the floating of the kayak and its total transparency.
Patent NZ-753087-A (NZ)
Title: 2-amino-n-(arylsulfinyl)-acetamide compounds as inhibitors of bacterial aminoacyl-trna synthetase
Inventor: FINN PAUL WILLIAM
IPC: A61P31/04
Filed: 2017-10-06
Abstract: The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain 2-amino-N-(arylsulfinyl)- acetamide compounds that, inter alia, inhibit (e.g., selectively inhibit) bacterial aminoacyl- tRNA synthetase (aaRS) (e.g., bacterial leucyl-t RNA synthetase, LeuRS). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitroand in vivo, to inhibit (e.g., selectively inhibit) bacterial aminoacyl-tRNA synthetase; to treat disorders that are ameliorated by the inhibition (e.g., selective inhibition) of bacterial aminoacyl-tRNA synthetase; to treat bacterial infections; etc.
Patent NZ-763864-A (NZ)
Title: Chemically-strengthened thin glass substrates new paradigms for modified curvature and methods of manufacture
Inventor: ALDER RICHARD ASHLEY
IPC: C03C21/00
Filed: 2018-10-17
Abstract: Chemically-strengthened thin glass having modified curvature and a method for making the same. The method includes providing a thin glass substrate which has host alkali ions situated in its surface regions, and possesses a treatment-advantaged surface region and a treatment-disadvantaged surface region located opposing each other; conducting a step of ion-exchange with invasive alkali ions having an average ionic radius larger than the average ionic radius of the host alkali ions, thereby producing a chemically-strengthened substrate which is characterized by an undesired curvature (warpage), and then conducting a step of reverse ion-exchange with reversing alkali ions having an average ionic radius equal to, or smaller than, the average ionic radius of the host alkali ions before ion-exchange, so as to produce a chemically-strengthened substrate having either less curvature or having a predetermined profile of curvature, which is not present in the chemically-strengthened glass substrate prior to reverse ion-exchange.
Patent PT-100222-A (PT)
Title: Anti-hypertensive agents based on glutaramides derived from cyclopentane
Inventor: JAMES KEITH
IPC: A61K/
Filed: 1992-03-11
Abstract: The present invention relates to compounds of the formula: <IMAGE> in which R1 and R2 each independently represent H or a biolabile ester forming group, and one or both of OR1 and R2 can be optionally substituted by NH2; R3 represents, for example: <IMAGE> in which R5 represents H or methyl, R6 represents H or halo, and n represents 0 or 1; and R4 represents H or hydroxy; and pharmaceutically acceptable salts thereof; and to the process for the preparation thereof. These compounds are diuretic and natriuretic agents, of use in the treatment of hypertension, heart failure, renal insufficiency and other diseases.