baber/WOPTO huggingface dataset:
Patent CR-20130601-A (CR)
Title: Derivados de pirazol útiles como inhibidores de aldosterona sintasa
Inventor: BELL MICHAEL GREGORY
IPC: A61K31/416
Filed: 2013-11-18
Abstract: La presente invención se refiere a inhibidores de aldosterona sintasa de la fórmula:
Patent CR-20180579-A (CR)
Title: Compuestos de 1-tetrahidropiranilcarbonil-2,3-dihidro-1h-indol para el tratamiento de cáncer
Inventor: BASTIAN JOLIE ANNE
IPC: C07D405/06
Filed: 2017-05-31
Abstract: La presente invención se refiere a ciertos nuevos compuestos de 2,3-dihidro-1H-indol, composiciones farmacéuticas que comprenden los compuestos y métodos de uso de los compuestos para tratar cáncer, más particularmente para el tratamiento de cáncer seleccionado del grupo que consiste de melanoma, leucemia mieloide aguda, leucemia linfocítica crónica, cáncer colorrectal, cáncer de mama, cáncer de pulmón, cáncer de ovario, carcinoma de trompa de Falopio, carcinoma peritoneal primario, cáncer cervical, cáncer gástrico, cáncer de hígado, cáncer pancreático, cáncer de tiroides, glioblastoma, linfoma no Hodgkin y linfoma de Hodgkin.
Patent CR-20230224-A (CR)
Title: System for treating thrombus in body lumens
Inventor: NGUYEN HOA
IPC: A61B17/22
Filed: 2021-10-20
Abstract: The present disclosure relates generally to thrombectomy devices. An exemplary catheter comprises: a central tube; an emitter assembly mounted over the central tube, wherein the emitter assembly comprises: a conductive sheath; a first insulated wire having a first curved distal portion; and a second insulated wire having a second curved distal portion, wherein the first curved distal portion and the second curved distal portion are positioned within the conductive sheath, and wherein the emitter assembly is configured to generate a plurality of cavitation bubbles or shockwaves when a pulsed voltage is applied to the emitter assembly; and an outer tube housing the emitter assembly, wherein the outer tube is configured to receive a conductive fluid, wherein the outer tube comprises a distal opening for releasing the plurality of cavitation bubbles or shockwaves and the conductive fluid in a forward direction to treat thrombus at a treatment site.
Patent EC-SP055573-A (EC)
Title: COMPOSICIÓN QUE COMPRENDE UN INHIBIDOR DE LA ABSORCIÓN DEL COLESTEROL, UN INHIBIDOR DE HMG-CoA REDUCTASA Y UN AGENTE ESTABILIZANTE
Inventor: MOORE WILLIAM D
IPC: A61K45/06
Filed: 2005-01-25
Abstract: La presente invención proporciona una composición farmacéutica que comprende un inhibidor de la absorción de colesterol y un inhibidor de una HMG-CoA reductasa, uno o más antioxidantes, celulosa microcristalina, hidroxipropil metilcelulosa, estearato de magnesio y lactosa. La composición no necesita contener ácido ascórbico en orden de obtener la estabilidad deseable.
Patent EC-SP066399-A (EC)
Title: Metanosulfonato del éster etílico del ácido 3-[(2-{[4-(hexiloxicarbonilamino-imino-metil)-fenilamino]-metil}-1-metil-1h-bencimidazol-5-carbonil)-piridin-2-il-amino]-propiónico y su utilización como medicamento
Inventor: SIEGER PETER
IPC: A61K31/4439
Filed: 2006-03-01
Abstract: Objeto del presente invento es el compuesto metanosulfonato del éster etílico del ácido 3-[(2-{[4-(hexiloxi-carbonilamino- -imino-metil)-fenilamino]-metil}-1-metil-1H-bencimidazol-5- -carbonil)-piridin-2-il-amino]-propiónico en las modificaciones cristalinas I y II, así como semihidrato, y su utilización como medicamento.
Patent EC-SP099490-A (EC)
Title: Métodos de fabricación y uso de compuestos y composiciones
Inventor: HARRISON BOYD LYNN
IPC: A61K31/4155
Filed: 2009-07-03
Abstract: La presente invención provee compuestos y composiciones, métodos para su fabricación y métodos para su uso a fin de modular los receptores nicotínicos de acetilcolina ?7 y/o para el tratamiento de cualquiera de los diversos trastornos, enfermedad y factores. Los compuestos provistos pueden afectar, entre otras cosas, al sistema neurológico, psiquiátrico y/o inflamatorio.
Patent EC-SP951381-A (EC)
Title: Envases huecos con superficie interna inerte o impermeable por reaccion superficial asistida por plasma o por polimerizacion sobre superficie
Inventor: PLESTER GEORGE
IPC: B29D24/00
Filed: 1995-02-09
Abstract: El presente invento se proporciona polimerización asistida con plasma y deposición de un revestimiento de superficie interna muy delgado en un envase plástico o metálico sin un aumento deseable en la temperatura superficial del envase para modificar las propiedades superficiales de la superficie plástica interna de un envase por reacción de la superficie con un gas reactivo que ha sido energizado para producir un plasma o la superficie es activada por un plasma de gas reactivo de manera que se haga receptora a otra reacción superficial. El método comprende ubicar el envase en un recinto cerrado, insertar elementos para alimentar un gas reactante dentro del envase, controlar selectivamente la presión dentro del recinto cerrado y dentro del envase, limpiar una superficie del envase a ser revestida in situ, pre-tratar la superficie a ser revestida para permitir que un revestimiento polimérico subsiguientemente depositado sobre la misma asegure la correcta adhesión entre el material de revestimiento y el material de envase, alimentar un gas reactante de constitución predeterminada y que tenga propiedades de barrera dentro del envase, generar un plasma con dicho gas reactante y depositar un revestimiento polimérico relativamente delgado sobre la superficie a ser revestida, y efectuar un tratamiento de post-polimerización sobre dicho revestimiento polimérico para eliminar monómeros residuales y otros extractables poliméricos in situ después de la deposición de dicho revestimiento polimérico.
Patent EC-SP951500-A (EC)
Title: Derivados de bencimidazol
Inventor: FARACI WILLIAM S
IPC: C07D235/04
Filed: 1995-08-04
Abstract: Se refiere a nuevos derivados de bencimidazol farmacéuticamente activos de fórmula: en la que la línea punteada, X y R1 a R7, R11 y R15 a R17 se definen como en la descripción. Estos compuestos muestran actividad dopaminérgica central y son útiles en el tratamiento de trastornos del SNC.
Patent EC-SP992837-A (EC)
Title: Derivados de 1,3,4 oxadiazolona
Inventor: DING MIN
IPC: A61K9/00
Filed: 1999-01-22
Abstract: La presente invención proporciona derivados de oxadiazolona novedosos que tienen la fórmula general (gráfico), en donde A, B, D y R son como se definio aquí, o una sal farmacéuticamente aceptable no tóxica o solvato del mismo y es útil en el tratamiento de trastornos que son en respuesta a la apertura de los canales de potasio activados con calcio, de alta conductividad (BK).
Patent FI-20002531-A (FI)
Inventor: AALTONEN JANNE U
IPC: H04W88/18
Filed: 2000-11-17
Abstract: A method of transmitting messages in a telecommunication system includes a first network offering circuit-switched services, a second network offering packet-switched services, and at least one mobile station supporting the first and the second network. When the need arises to transmit at least one message, a check is made to see if the mobile station is attached to the second network. The message is transmitted to the second network if the mobile station is attached to the second network. The message is transmitted to the first network in case of a failure to transmit the message via the second network.
Patent FI-20040117-A (FI)
Inventor: COOLEY DAVID M
IPC: H04W4/18
Filed: 2004-01-28
Abstract: The present invention provides a method of minimizing synchronization delay in a radiotelephone system between a modular subscriber cluster communicating with a common base station, the modular subscriber cluster receiving repetitive time slots from the base station and having a plurality of frequency-agile modems, the method comprising the steps of: 
synchronizing a selected one of the modems to a selected time slot of the received time slots; 
generating a frame sync signal from said selected modem; and distributing said frame sync signal to remaining ones of the plurality of modems.
Patent FI-20105154-A (FI)
Inventor: AHVENAINEN ARTO
IPC: F23G5/027
Filed: 2010-02-17
Abstract: The invention relates to a fluidized bed gasification system and a method of gasifying fuel in a fluidized bed gasification system, said gasification system comprising a fluidized bed gasification reactor and a fluidized bed combustion reactor, and in which a first fluidized bed reactor of said fluidized bed gasification reactor and fluidized bed combustion reactor is a circulating fluidized bed reactor, a first portion of there circulating means of which is arranged gas- tight inside the reaction chamber of a second fluidized bed reactor for gasifying fuel to be gasified by transferring heat from the particles of the fluidized bed combustion reactor through the outer wall of the first portion to the particles of the fluidized bed gasification reactor.
Patent GB-1050109-A (GB)
IPC: B65D88/12
Abstract: 1,050,109. Cargo platforms. E. BAKER. Sept. 18, 1964 [Sept. 18, 1963], No. 36719/63. Heading B8H. A unit for transporting goods comprises two or more cargo flats disposed one above the other or others. Each, cargo flat has a base 1 with a lip 2. Pegs 4 on head and tail boards 5 fit into sockets 3 and a second flat is tiered on the first by grooves 10 engaging tongues 9, supports 6 pivoted at 7 constituting struts attached at their free ends 8 to the upper flat. Each flat has four lifting lugs 11 of S-form free to pivot about pins 12. Corresponding lugs 11 are interconnected by a cable or rope tensioned by a bottle screw 13. More than two flats may be tiered, and the tiered flats may be lifted as a unit by the lugs 11 on the top flat.
Patent GB-1051540-A (GB)
IPC: B23H7/28
Abstract: 1,051,540. Electro-erosion. EXPERIMENTALNY NAUCHNO-ISSLEDOVATELSKY INSTITUTE METALLOREZHUSHTCHIKH STANKOV. July 4, 1963, No. 26505/63. Heading B3. [Also in Division H3] In a high-frequency electro-erosion process wherein the electrode forms the anode and the workpiece forms the cathode unipole impulses of 100-600 volts are applied to the gap and the resultant discharges have a ratio of the energy of a separate impulse to the average energy over a cycle in the range 1 to 5. The pulses are generated by valves 1L, 2L, Fig. 1, with frequency selector switches S 1 -S 4 , and are passed through control potentiometer 11R, voltage amplifier 3L, parallel connected current amplifiers 4L, 5L and transformer IT to output valves 6L, 7L and 8L, 9L working in push-pull. These valves are fed with anode current from high-voltage transformer 2T, rectifiers 1V-6V and filter 1D, 12C. The output pulses are delivered through output transformer 3T, diode 7V and variable resistors 27R, 28R to the erosion gaps E 1 , E 2 . Switches S 5  and S 6  enable one or both gaps to be used. Transformer 3T has an air gap and steel laminations giving a high magnetic permeability; the windings are filled with an epoxy resin. Diode 8V and a non- linear resistor, such as an incandescent lamp L, are connected in parallel with the erosion gaps. Resistors 27R, 28R control the current in the gaps. The electrode 19, Fig. 2 (not shown), may be gyrated without rotation in a plane perpendicular to its feed direction by means of radially mounted electromagnets 8, Fig. 3 (not shown), energized in sequence. The amount of gyration is controlled by a conical projection 37 carried by the gyrating part engaging an apertured former 26 whose vertical position is adjustable by knob 32 for varying the gyration. Alternatively or additionally the workpiece 40 may also be gyrated by similar mechanism. The electrode or the workpiece may also be oscillated in the feed direction. Dielectric fluid is pumped through connection 41 and ducts 42 to the erosion gap which is immersed in a fluid bath 43. Alternatively the fluid may be sucked from the gap.
Patent GB-1052097-A (GB)
IPC: E04G19/00
Abstract: 1,052,097. Shuttering for casting floors &c. SOC. ANON. RHODIUS-DEVILLE. May 29, 1964 [May 31, 1963], No. 22442/64. Heading E1S. Shuttering 8 for casting floors &c. rests on a frame 6 supported on girders 5 carried by hydraulic jacks 3 on a wheeled carriage 1 and also on extensible props 9 which support the shuttering when the carriage 1 is removed to place other shuttering in position.
Patent GB-1052922-A (GB)
IPC: B43K24/16
Abstract: 1,052,922. Multiple retractable ball-point pens. W. A. BOSSERT. Aug. 21, 1963 [Aug. 22, 1962], No. 33039/63. Heading B6P. In a multiple retractable ball-point pen having a telescopic cap portion 2, a drop lever 15 is supported within the cap 2 from a member 14 of polygonal cross-section. Tilting the pen in a particular direction selects the particular writing member holder 3 to be projected. The member 14 slides within a complementary sleeve 16 fixed to the barrel portion 1 of the pen and prevents any relative rotation between the cap 2 and the barrel 1. Guide lugs 17 projecting within the sleeve 16 guide the lever into cooperation with the particular holder 3 to be selected. The retaining mechanism of the projecting mechanism comprises two cylindrical members 4 and 7, Fig. 3, mounted within the barrel 1. A guide lug or ear 5 on each holder 3 co-operates with a slot 6 in member 4 and cam surface 8 on member 7. A selected holder 3 is retained in the projected position by the cam 8 until another holder 3 is projected which partly rotates member 7 within member 4, thus releasing the holder 3 which is retracted by a tension spring 12. Cut-away portions (not illustrated) at the top of the cap 2 allow different coloured sections of portion 22 to be seen, thus illustrating the various colours and positions of the writing members within the barrel. The writing members may be ball-point pen cartridges or pencil leads.
Patent GB-1053520-A (GB)
IPC: A44B17/00
Abstract: 1,053,520. Stud and socket fastenings. SCOVILL MANUFACTURING CO. Oct. 20, 1964 [Oct. 31, 1963], No. 42785/64. Heading E2B. A snap fastener resilient stud consists of a plastics material e.g. nylon which is substantially rigid in thicker sections and flexible and resilient in thinner sections the stud having a base 18 adapted to bear against a piece of supporting material, an upstanding inwardly yieldable circular flange 19 projecting from the base and an upstanding solid projection 23 integral with the base and surrounded by the flange the upward extent of the projection from the base being at least as much as that of the circular flange. In the construction shown the flange has a bead 20 and it is divided by slots 22 to increase the resiliency. The flange is engageable with a socket which has a base 7 and a circular flange 8 shaped so as to provide a constricted entrance opening 9 with a lead-in surface 10, the opening receiving the flange 19 of the stud. To prevent interference between the projection 23 and the inner surface of the socket the socket is provided with a recess 17. Both the stud and the socket are provided with a post 13 which by the application of heat and pressure forms a rivet head which bears against a shoulder 15 of a plastic eyelet 11 to secure the stud or socket to the supporting material.
Patent GB-1053921-A (GB)
IPC: G06F7/02
Abstract: 1,053,921. Recording apparatus. CALIFORNIA COMPUTER PRODUCTS Inc. May 21, 1963 [May 21, 1962], No. 20254/63. Heading G1J. A graphical plotter for digital data recorded on magnetic or like tape in the form of positive and negative increments to variables x and y is provided with control circuits sensing the increment signals from a group including various control signals identifying blocks of data, &c., and commanding the appropriate x and y relative movements of pen and paper. Movement of the pen into and out of contact with the paper may also be commanded; this is referred to as +z, -z respectively. The x signals control rotation of a drum holding the paper, and y signals the movement to left or right of a pen-carrying carriage. Other aspects of the system are the subject of Specifications 1, 053, 922, 1, 053, 923 and 1, 053, 924.
Patent GB-1226029-A (GB)
IPC: C07C45/73
Filed: 1968-11-07
Abstract: 1,226,029. Methyl isobutyl ketone. BP CHEMICALS Ltd. 15 Oct., 1969 [7 Nov., 1968], No. 52811/68. Heading C2C. Methyl isobutyl ketone is prepared by passing hydrogen and a mixture of acetone and a sulphonic or carboxylic acid in the liquid phase over a platinum group metal catalyst supported on a carrier at elevated temperature and pressure. The acid preferably has an ionization constant greater than 1.0 x 10<SP>-3</SP> and is suitably a halogen - substituted aliphatic or aromatic carboxylic acid or an aliphatic, benzene or toluene sulphonic acid. Isopropanol, mesityl oxide, di-isobutyl ketone and various hydrocarbons are produced as by-products.
Patent GB-1227343-A (GB)
IPC: F23D14/12
Filed: 1967-04-11
Abstract: 1,227,343. Burners. AIROIL BURNER CO. (GB) Ltd. 9 April, 1968 [11 April, 1967], No. 16645/67. Heading F4T. A burner for liquid or gaseous fuel or a combination of both includes a main housing 4 with an air inlet 6 and damper 7 and a burner head which comprises a funnel-shaped shroud 8 fixed to a support tube 9 extending into the housing, the shroud 8 being attached to a gas inlet tube 10 which with a tube 14 forms an annular passage 16 for gaseous fuel and liquid fuel being supplied via an injector 15 and tube 17 to a nozzle 28. Circumferentially arranged air passages 20, 21 located in the widest part of shroud 8 are directed forwardly and obliquely to the burner axis and air passing through passages 22 in the narrow part of the shroud keeps the burner nozzle free from liquid fuel.
Patent GB-1230580-A (GB)
IPC: A63B55/00
Filed: 1968-03-05
Abstract: 1,230,580. Hood for golf club bags. I. R. PLATT. 4 June, 1969, No. 40483/67. Heading A6D. A hood for golf club bags is formed of a flexible waterproof material and the open end of the hood can be drawn over the open end of the bag so as to cover the heads of the clubs inserted therein. The hood has an opening or window extending across one side thereof through which the clubs can be withdrawn and is provided with a flexible waterproof flap or flaps bonded or otherwise secured in a waterproof manner to the hood above the opening or window and normally covering the opening or window. Eeither the hood or the flap may be transparent. The hood may be provided with an opening through which the shaft or spline of a caddie car can be inserted, the opening having means by which a water-tight seal is formed between the rim or edge of the opening and the shaft or spine. As shown in Figs. 1, 3 and 4. The hood 10 is formed of transparent or opaque P.V.C. or polyethylene and is of such dimensions that it can be slipped over the open end of the golf club bag 11 and will cover the heads 12 of the clubs 13 inserted in the bag. The open end 14 of the hood is reinforced to prevent its tearing and provided with a draw cord 15 or an elastic band by which the hood can be securely anchored to the bag. Somewhat below the top of the hood one face of the hood has a cut out window or opening 16 which extends across the heads 12 of the rows of the clubs 13. To the hood, just above the opening 16 is bonded at 19 a flexible waterproof flap 20 which more than covers the opening. The hood is further provided with an opening 21 through which extends the shaft or spine 22 of a caddie car. The opening 21 is provided with a neck 23 and a draw cord 24 or a resilient sealing member inserted in the neck 23.
Patent GB-1238766-A (GB)
IPC: A44B19/40
Filed: 1969-05-13
Abstract: 1,238,766. Sewing. OPTI-HOLDING A.G. 13 May, 1969 [15 May, 1968], No. 24309/69. Heading D1G. A sliding clasp fastener has tapes, (1), (2) Fig. 1 (not shown) in which gaps to enable easy attachment by sewing to an article, &c. are made by displacing the warp threads 6 transversely to the length of the fastner. A process by which gaps in sliding clasp fastner tapes of the type described above may be produced involves using a machine similar to a sewing machine in which assymetrically shaped needles 8, 9, 10 are mounted. The warp threads 6 are progressively displaced by the oblique edges 12 of the needles.
Patent GB-1251652-A (GB)
IPC: B43K17/02
Filed: 1968-07-01
Abstract: 1,251,652. Reservoir brushes. E. PETERSEN AND H. S. PETERSEN. Sept. 29, 1969 [July 1, 1968], No.31399/68. Heading A4K. [Also in in Division B6] A plurality of marking elements, including, if desired, a spiked element are housed in a single socket lined with a V-shaped sheet of plastics material and a pad of resilient material. Windows 10 allow the element 5 to be easily removed, and the spiked element enables concentric circles to be drawn. (For figure see next page)
Patent GB-1252488-A (GB)
IPC: H03F3/19
Filed: 1969-05-19
Abstract: 1,252,488. Transistor amplifying circuits. RCA CORPORATION. 19 May, 1969 [20 May, 1968], No. 25377/69. Heading H3T. In a video amplifier a delay line 20 is coupled between the emitter of an emitter-follower 15 and the emitter of a common-base stage 23. Resistors 18, 22 provide the correct terminating impedance at either end of the delay line, a toppeaking coil 21 also being provided. The arrangement is direct-coupled to a common emitter stage 35 in which the emitter-circuit decoupling capacitor 38 only comes into operation at the higher frequencies, so as to give further top-peaking; this is followed by an emitter-follower 40 driving the output stage 50. Overall negative feedback is provided by the network 25, 26, 45, 46, 47, 48, the shunt arm 47, 48 being arranged to reduce the feedback at higher frequencies, to produce top-peaking. Brightness is controlled by the variable resistor 26 in the emitter circuit of transistor 23. The arrangement comprises the luminance channel of a colour television receiver, and the emitter circuit of transistor 15 also feeds A.G.C., sync. and chrominance channels of the receiver.
Patent GB-1252559-A (GB)
IPC: F02P3/04
Filed: 1970-06-15
Abstract: 1,252,559. Ignition systems. LUMENITION Ltd. June 15, 1970, No. 28855/70. Addition to 1,219,833. Heading F1B. In a transistorized ignition system as claimed in claim 1 of Parent Specification means L are provided for controlling the switching speed of the switching means 28. The radiation sensitive element 50, 51 may be a photo darlington pair or triplet. A Zener diode Z may be connected in parallel with the radiation source 10 and the radiation sensitive element so as to stabilize the operating voltage.