baber/WOPTO huggingface dataset:
Patent EC-SP034905-A (EC)
Title: Sistema de inhalación de polvo seco para administración transpulmonar
Inventor: YAMASHITA CHIKAMASA
IPC: A61K9/19
Filed: 2003-12-15
Abstract: La presente invención proporciona un nuevo sistema de inhalación de polvo seco adecuado para la administración transpulmonar. El sistema de inhalación de polvo seco de la invención caracterizado porque usa una combinación de: un recipiente que contiene una composición secada por congelamiento que contiene una única dosis de un ingrediente activo, y tiene:1)	una forma tipo pastilla en forma distinta de polvo,2)	un índice de desintegración de 0,015 o más, y3)	una propiedad para convertir las partículas finas que tienen un diámetro de partícula medio de 10 micrones o menos o una fracción de partículas finas de 10% o más luego de recibir un impacto de aire que tiene una velocidad de aire de al menos 1 m/seg y una velocidad de flujo de aire de al menos 17 ml/seg; yun dispositivo que comprende medios capaces de aplicar dicho impacto de aire a la composición secada por congelamiento en dicho recipiente, y medios para descargar la composición secada por congelamiento en polvo que ha sido dividida en partículas finas.
Patent EC-SP045203-A (EC)
Title: Cicloalcanindoles con sustitución con flúor y su uso como antagonistas del receptor prostaglandina d2
Inventor: BERTHELETTE CARL
IPC: A61P11/06
Filed: 2004-07-22
Abstract: Los derivados cicloalcanindólicos con sustitución con flúor son antagonistas de las prostaglandinas y, como tal, son útiles para el tratamiento de las enfermedades mediadas por las prostaglandinas.
Patent EC-SP066520-A (EC)
Title: Derivados de dihidrobenzofuranilo alcanamina y métodos para su uso
Inventor: STACK GARY PAUL
IPC: A61K31/343
Filed: 2006-04-24
Abstract: Se proporcionan compuestos de fórmula 1 o sales farmacéuticamente aceptables de los mismos: Fórmula 1que son agonistas o agonistas parciales de los receptores del subtipo 2c de la serotonina cerebral. Los compuestos, y composiciones que contienen los compuestos, se pueden utilizar para tratar una variedad de trastornos del sistema nervioso central tales como esquizofrenia.
Patent EC-SP088862-A (EC)
Title: Formulaciones de dosificación sólida
Inventor: DIORIO CHRISTOPHER RICHARD
IPC: A61K9/28
Filed: 2008-11-05
Abstract: Las Formulaciones de dosificación sólida se proporcionan para un compuesto que tiene la fórmula (I); R2 = Cl, F, Br, CH3, CF3, SCH3, NHCH3, NO2, CN, OH, Oalquilo C1-C6, o Oalquilo C1-C6 sustituido, o un profármaco o su sal farmacéuticamente aceptable. Se describen las formulaciones para comprimidos y multiparticulados que contiene un compuesto de acuerdo con la fórmula anterior, un componente que controla la velocidad, y un aglutinante, que incluyen formulaciones que contienen un recubrimiento de sello, recubrimiento que controla velocidad de liberación, y/o recubrimiento entérico. También se describen usos y kits farmacéuticos de éstos.
Patent EC-SP099321-A (EC)
Title: Combinaciones de herbicidas con sulfonilureas especiales
Inventor: BICKERS UDO
IPC: A01N43/40
Filed: 2009-05-12
Abstract: Las combinaciones de herbicidas con un cierto contenido de componentes (A) y (B) tienen efectos herbicidas mejorados: (A) uno o varios herbicidas tomados del conjunto formado por los compuestos de la fórmula (I) y sus sales, (I) y (B) uno o varios herbicidas tomados del conjunto formado por los compuestos de la fórmula (II) y sus sales y ésteres, en la que R1 = es fluoro o cloro, R2 = es H o cloro, R3 = es H o NH2, y R4 = es COOH, OCH2COOH, OCH2COOCH(CH3)CH2O(CH2)3CH3 o OCH2COOCH(CH3)(CH2)5CH3, siendo diferente de H por lo menos uno de los radicales R2 y R3
Patent EC-SP972002-A (EC)
Title: Tienil -y furanil-oxazolidinonas piridocondensadas
Inventor: ENDERMANN RAINER
IPC: C07D413/04
Filed: 1997-01-16
Abstract: La presente invención se refiere a nuevas tienil - y furanil - oxazolidinonas, piridocondensadas, procedimiento para su producción y su uso como medicamento, especialmente como medicamento antibacteriano.
Patent EC-SP982403-A (EC)
Title: Metodo de uso de compuestos neurotropicos de sulfonamidas
Inventor: HAMILTON GREGORY S
IPC: C07C311/00
Filed: 1998-02-11
Abstract: Esta invención esta relacionada con un método de uso de compuestos neurotrópicos de sulfonamidas de bajo peso molecualr y de molécula pequeña, que tienen afinidad con las inmunifilinas tipo FKBP, y su uso como inhibidores de la actividad enzimática asociada con las proteínas de inmunifilina, particularmente la actividad enzimática de la peptidil-prolil isomerasa, o rotamasa.
Patent EC-SP982414-A (EC)
Title: Aminoacidos aromaticos biciclicos
Inventor: RADDATZ PETER
IPC: A61K31/335
Filed: 1998-02-13
Abstract: Los compuestos de fórmula I (gráfico), en donde X, Y, Z, R1, R2, R3, R4, R5, R7, R8, R11, m y n tienen los significados indicados en la reinvindicación 1, y sus sales aceptables desde el punto de vista fisiológico pueden ser empleados en calidad de inhibidores de la integrina, en particular para la profilaxis y el tratamiento de las enfermedades del sistema circulatorio, de trombosis, infarto de miocardio, enfermedades coronarias, arteriosclerosis, osteoporosis, procesos patológicos que se mantienen o se propagan por angiogénesis y en la terapia de los tumores.
Patent EC-SP993063-A (EC)
Title: Nuevo metodo para reducir o prevenir la apoptosis de celulas diferenciadas
Inventor: BUCKINGHAM ROBIN EDWIN
IPC: A61K45/06
Filed: 1999-07-20
Abstract: Un método para reducir o prevenir la apoptósis de células diferenciadas seleccionadas entre la lista que consta de miocitos cardiacos, células beta pancreáticas, endoteliales y células neuronales en un mamífero humano o no humano, cuyo método comprende la administración, inclusive la administración en un régimen agudo, de una cantidad no tóxica y eficaz de un intensificador de la absorción de glucosa a un mamífero humano o no humano que necesita de ello.
Patent EC-SP993277-A (EC)
Title: 4,5- azolo- oxindoles
Inventor: LUK KIN CHUN
IPC: C07D403/14
Filed: 1999-12-17
Abstract: 4,5-azolo-oxindoles nuevos con la fórmula (gráfico), donde R1, R2, Y, Z ya tienen el significado indicado en la especificación, inhiben las quinasas dependientes de ciclina (CDKs), en partcular CDK2, y son útiles en el tratamiento o control de los desórdenes proliferativos celulares, en particular el cáncer.
Patent EE-9900539-A (EE)
Inventor: DAVID CHESHIRE
IPC: C07D239/00
Filed: 1998-05-18
Abstract: The invention provides pharmaceutically useful thieno[2,3-d]pyrimidinediones, processes for their production, pharmaceutical compositions containing them and methods of treatment involving their use.
Patent FR-1604683-A (FR)
Title: Piezoelectric ceramics - for ultrasonic transducers contg silver-bismuth-lead-titanate-zirconates
IPC: C04B35/50
Filed: 1968-12-30
Granted: 1972-01-03
Abstract: Piezoelectric ceramics consisting of solid solns. from the quat. system (Ag1/2Bi)TiO3-(Ag1/2Bi1/2)ZrO3-PbTiO3-PbZrO3 in which is not >25% of Pb may be replaced by Ca, Sr or Ba. In particular compsns. within the area ABCDEFG defined by the parameters alpha, beta so that for A alpha = 0.01, beta = 0.55; B alpha = 0.01, beta = 0.10; C alpha = 0.05, beta = 0.05; D alpha = 0.10, beta = 0.05; E alpha = 0.20, beta = 0.30; F alpha = 0.20, beta = 0.70; G alpha = 0.10, beta = 0.70; H alpha = 0.05, beta = 0.70 where alpha = t/((t+v) = u/(u+w) and beta = t/(t+tu) = v/(v+w) from the general formula (Ag1/2Bi1/2)TiO3 t (Ag1/2Bi1/2)TiO3 u PbTiO3 v PbZrO3 w. The materials have high electrochemical coupling factors and are used for ultrasonic transducers.
Patent GB-1050813-A (GB)
IPC: C01B25/22
Abstract: 1,050,813. Concentrating phosphoric acid. ALBRIGHT & WILSON Ltd. June 24, 1964 [June 28, 1963; Feb. 26, 1964], Nos. 25805/63 and 8060/64. Heading C1A. [Also in Division B1] In the concentration of wet process phosphoric acid by submerged flame evaporation, the product acid, containing at least 50% by weight P 2 O 5 , is recovered from the distillate instead of from the residue as in the prior art. As shown, crude acid is fed continuously to vessel 2 via pipe 7, and is heated by combustion gases emerging from holes 4 in burner 1. The flame temperature is at least as hot as that obtained by burning a hydrocarbon in the stoichiometric quantity of air, i.e. about 1600 C., and in the high turbulent region by the burner mouth a gas-liquid mixture comprising water vapour, distilled P 2 O 5  acids, volatile impurities and impure aqueous acid is formed. The mixture travels via annular passage 6 to region 8 of higher cross-sectional area where the liquid phase separates from the gaseous phase and returns to the region of the burner mouth via passage 10. Residual crude acid leaves the pot through pipe 11, controlled by adjustable weir 13 and pressure seal 14. Distilled P 2 O 5  acids condense on the gaseous phase as an aerosol which leaves the vessel via pipe 9 and the aerosol particles, after separation from entrained crude acid in a cyclone, are coalesced in a scrubber while the temperature is maintained above that at which volatile impurities will condense, i.e. above 150 C. The scrubber may be a Venturi into the throat of which some of the product acid is injected. An alternative distillation vessel is a U-tube with the burner projecting horizontally into one horizontal limb.
Patent GB-1051662-A (GB)
IPC: G11C19/08
Abstract: 1,051,662. Magnetic storage devices. INTERNATIONAL COMPUTERS & TABULATORS Ltd. Jan. 20, 1964 [Feb. 12, 1963], No. 5656/63. Heading H3B. [Also in Divisions G4 and H1] A magnetic thin film shift register in which a bit entered at one end of a strip of film is moved along the strip by phased setting and resetting currents in a set of transverse conductors, employs a larger resetting current than that used for setting, thus ensuring that small pockets of set magnetic film are not left behind as the set zone advances. The film 1 is normally magnetized as at 22 along its easy axis, and the setting current (line W) in conductors I (three sets of series-connected conductors are employed here) is just sufficient to switch the film at a boundary with an already set area 23, but not elsewhere. At the same time a larger resetting current is flowing in conductors 11. As this pattern advances (lines X-Z) the set zone 23 advances with it. A number of thin film registers may be parallely disposed beneath the conductors shown to form a plurality of synchronous but independent registers, and it is stated that four or more sets of transverse conductors may be used instead of three.
Patent GB-1095381-A (GB)
IPC: F16L41/06
Abstract: 1,095,381. Drilling; welding by fusion. WALLACE SUPPLIES MANUFACTURING CO. Aug. 23, 1965 [Jan. 18, 1965], No. 36012/65. Headings B3B, B3C and B3R. [Also in Division B5] A machine for cutting a circular hole in a tube 37 &c., comprises a work-holder 36 and a tool arbor 22 on a carriage 16 reciprocable by power means to and from the workholder. The carriage moves on rods 14. The circular saw 30 has a base-plate 31 screwed to a flywheel 25 attached by a setscrew 27 to an arbor 22 rotated by variable-speed gearing 21 and a motor 18. The saw is supported, during cutting, by a bush 38. The carriage 16 is advanced by pneumatic means 50 against fluid resistance adjusted by a valve 57. The pneumatic system includes an air accumulator tank 58, a gauge, a filter and a lubricator. The work is held by chain clamps 81, on a bracket 71 adjustable by a screw 76 on a base 67 which is adjustable about a pivot 66. Two pipes may be cut simultaneously as shown in Fig. 9. Welding.-A piece of pipe 91, Fig. 10, may be cut as described in Specification 883,362, tackwelded to a pipe 91 and used as a guide for drilling a hole in a pipe 90, the bush 38 having been removed. The pipe 91 is then knocked off and the branch pipe welded in place, the weld metal 88 entering a V-groove in the branch pipe.
Patent GB-1143822-A (GB)
IPC: H01H36/00
Abstract: 1,143,822. Piezo-electric switches; mercury switches. SIEMENS A.G. 18 Aug., 1966 [20 Aug., 1965], No. 37010/66. Heading H1N. On bending of a piezo-electric crystal 1 on excitation, said crystal 1 forming a dividing wall between two pressure chambers 2 containing non-conductive liquid, the equalization of liquid volume occurs through a bore 3 containing a mercury drop 4 and causes this drop 4 to break contacts 5a<SP>1</SP>, 56<SP>1</SP> and make contacts 5a, 5b. Drop 4 is held in bore 3 by a mesh 6 at each end. The ends of the bore 3 may be narrowed. In a modification, the bore 3 includes spherical enlarged ends (3a, 3b, Fig. 3), and the bore ends are closed by snap-acting discs (7a, 7b) impervious to the liquid. Equalization of volumes occurs through the snapping-over of the discs which consequently moves the drop 4. A capillary tube (8) through the crystal 1 provides for equalization of pressures. In a further modification (Fig. 4), the contacts are embedded in a ceramic moulding separate from the crystal and two crystals may provide opposite sides of a pressure chamber.
Patent GB-1225391-A (GB)
IPC: B65D90/34
Filed: 1968-08-20
Abstract: 1,225,391. Valves. WHESSOE Ltd. 11 July, 1969 [20 Aug., 1968], No. 39703/68. Heading F2V. A vent valve for a vessel, such as a rail tanker wagon, has a pallet 7 co-operating with a valve seat 5 and secured to a piston 4, a spring 9 biasing the piston and thereby the pallet on to the valve seat, and means 1 attached to the piston to enable the valve to be opened against the spring and any pressure loading from the vessel contents. The means 1 may be a Bowden cable connected to an operating lever for a discharge valve at the base of the vessel. When the vessel forms part of a rail tanker wagon, the operating lever is connected to hand levers at opposite sides of the wagon.
Patent GB-1226179-A (GB)
IPC: C07D243/10
Filed: 1968-07-30
Abstract: 1,226,179. Aza- and diaza - azulenes. STUDIENGESELLSCHAFT KOHLE m.b.H. 30 July, 1968 [31 July, 1967], No. 36280/68. Heading C2C. Novel compounds of Formulµ I and II in which the radicals R which may be the same or different represent H, alkyl, aryl or aralkyl are prepared by condensing a compound of Formula III with a compound of Formula IV, V, VI or VII wherein X is OH, alkoxy, NH 2 , dialkylamino, diarylamino, or aralkylamino; Y is = O, = NR or = N<SP>+</SP>(R) 2 A<SP>-</SP>; A is a chloride, bromide, iodide, perchlorate or fluoroborate ion and R<SP>1</SP> and R<SP>11</SP> are as defined for R above. The compounds are characterized by means of their picrate salts.
Patent GB-1227639-A (GB)
IPC: H01H13/74
Filed: 1969-10-03
Abstract: 1,227,639. Latching switches. PHILIPS ELECTRONIC & ASSOCIATED INDUSTRIES Ltd. 3 Oct., 1969 [4 Oct., 1968], No. 48667/69. Heading H1N. In a push-button array for actuating a plurality of sliding switches including at least two button rods 7, 9 journalled in the upright walls of a channel section member (1) so as to be slidable at right-angles thereto against springs 11, 13 and having a strip shaped locking bolt 23 extending parallel to the bottom of the channel and adapted to slide in a longitudinal direction against the force of a resetting spring 37, the bolt closes the open side of the channel and is secured therein by the resetting spring which is located at right-angles to the channel surface and is located at least partly directly above the strip and stressed in the direction of resetting, the spring being secured in a direction transverse of the longitudinal direction of the channel by one end of the spring being hooked into one of the upright walls of the channel, or into the bolt. The resetting spring is formed by a substantially hairpin shape length of wire having unequal limbs, a long limb bridging the distance between the upright walls of the channel and which hooks near each of its ends into a profile (35, 37) provided in each of the channel walls, and a short limb having a hook-like end gripping into a profile (41) provided in the bolt. The button rods 7, 9 have portions 15, 17 in the form of switching slides having contacts (not shown) fixed to them. Rods 7, 9 and portions 15, 17 may be separate parts interconnected either directly or by means of a coupling rod, or alternatively may be formed by a single piece of a synthetic resin. Extensions 29, 31 of the button rods 7, 9 move in profiled openings 25, 27 formed in bolt 23.
Patent GB-1227792-A (GB)
IPC: H01R39/38
Filed: 1968-03-18
Abstract: 1,227,792. Electric motors; two-part couplings. ROBERT BOSCH G.m.b.H. 18 March, 1968 [18 March, 1967], No. 49884/70. Divided out of 1,227,791. Headings H2A and H2E. A commutator motor, particularly a D.C. motor with a permanent magnet stator, has a moulded plastics carrier plate 17 arranged normal to the rotor shaft and carrying the brushes and flat plug contacts 33 anchored in slots in the plate, the brushes being connected to the contacts which also receive connectors on the supply cables. As shown, the motor casing comprises a pair of U-shaped plates 12, 13 which carry the rotor bearings and are secured to a central yoke 11. The carrier plate 17 is secured to the plate 12 by deformed shoulders (44). Brush-holders 21 are formed integrally with the carrier plate and are closed by spring covers after insertion of the brushes and their springs. The plug contacts are inserted in slots (31) open to the edge and one side of the plate 17, lugs 37 on the contacts passing through apertures in locally thickened portions 32 on the plate and being twisted to retain the contacts in position.
Patent GB-1231768-A (GB)
IPC: F16H3/66
Filed: 1970-03-05
Abstract: 1,231,768. Change-speed gear. GENERAL MOTORS CORP. 5 March, 1970 [11 April, 1969], No. 10616/70. Heading F2D. A torque-converter-driven automatic threespeed and reverse planet gear, for a motorvehicle, comprises equal planets 121, 121<SP>1</SP>, independently rotatable on a single or separate spindles 124 on a common carrier integral with an output shaft 14, and meshing front and rear suns 117, 137, the former through planetary idlers 119, the latter directly. An input shaft 13 is selectively clutchable to the front sun 117 through a one-way clutch 111 for one-way automatic low, or through a bridging disc clutch 91 for two way manual low, whilst the rear sun 137 is held by a double-wrap band-brake 148. For second speed the input shaft 13 is alternatively clutched to the ring gear 144 by a disc clutch 70. For third speed, direct-drive, the brake 148 is released and both clutches 70, 91 engaged together. Reverse is provided by engaging a disc brake 46 to hold the ring gear 144 and engaging the clutch 91 to drive the front sun 117. The disc clutches 91, 70 and brake 46 are engaged by spring-rotated pistons 103, 76, 39 respectively, supplied with fluid pressure by an input-driven pump 31. Fig. 4, not shown, uses the same train as Fig. 1, but modifies the clutch and brake arrangement as follows. The first speed lock-up clutch 91 is replaced by a rear clutch between the rear sun 137 and output shaft 14, which provides lock-up third speed, during which the second-gear clutch remains engaged but transmits a reduced torque in comparison with the Fig. 1 arrangement. The front brake is a doublewrap band identical with the rear and the two clutch-brake assemblies at the front and rear of the transmission are mirror images of each other.
Patent GB-1232379-A (GB)
IPC: E06B3/28
Filed: 1969-10-10
Abstract: 1,232,379. Window frames, glazing. ALUMINIUM-WALZWERKE SINGEL G.m.b.H. 10 Oct., 1969 [15 Oct., 1968], No. 49849/69. Headings E1J and EIR. A metal frame of U-shaped cross-section has a lower part 2 mounted on and secured by resilient latches to a rail 5, the rail being of U-shaped cross-section and fixed to masonry 6. Part 2 is formed with recesses 10 receiving the ends of resilient plastics latch members 7 which engage over flanges 8, 9 on the rail 5. A further latch 20 secures weather strip 15. Panes 1 are mounted on an elastic strip 21 having a central depression 22 and slots 45 allowing passage of water to drainage holes 23, whence it flows onto strip 15. Elastic glazing strips 24 and putty also support the panes 1. The frame is made up of sections with overlapping expansion plates 27, and the panes 1 are of U-shaped cross-section.
Patent GB-1233062-A (GB)
IPC: B23K15/00
Filed: 1968-07-18
Abstract: 1,233,062. Welding by fusion. KERNFORSCHUNG m.b.H. GES. FUER. 18 July, 1968 [18 July, 1967], No. 34298/68. Heading B3R. In electron beam welding workpieces of different metals which combine to form at least one brittle intermetallic compound, the beam is allowed to impinge on one only of the workpieces at a position spaced from the butt joint so that the compound exists only in a very narrow portion of the weld, the greater part of which has a composition widely spaced from that of the compound. A pulsed or continuous beam is formed. The composition of the greater part of the weld may be determined by directing the beam along a line parallel to the seam so that the weld consists of metal derived more from one workpiece than the other. Various combinations of the following metals may be so welded: titanium, zirconium, niobium, vanadium, aluminium copper, nickel, tantalum, stainless steel (18% Cr, 8% Ni), heat resistant steel, iron and alloys including these metals.
Patent GB-1250368-A (GB)
IPC: G04C3/08
Filed: 1969-10-08
Abstract: 1,250,368. Electrostatic motors. ETAB. PROCOR. 8 Oct., 1969 [8 Oct., 1968], No. 49428/69. Heading H2A. [Also in Division G3] A vibrator for driving a timing mechanism includes two electrodes 2, 5 forming the plates of condenser, the electrode 2 being mounted on a resilient blade 1 so that when a potential is applied to the electrodes, it is electrostatically attracted towards electrode 5 until the capacitor formed by the electrodes is discharged whereupon the blade 1 returns the electrode and the process is repeated. Both electrodes may be mounted on resilient blades, Fig. 2 (not shown) and in a further arrangement, Fig. 3, two electrodes 10, 11 mounted on a single resilient blade 12 and connected respectively to the terminals 15, 16 of a D.C. supply are located on opposite sides of fixed electrode 17. To start the vibrator one of the electrodes 10, 11 is moved towards the electrode 17 whereupon the latter is charged in the same sense so that it repels the electrode 10 and attracts electrode 11. As soon as electrode 11 approaches or contacts electrode 17 a charge reversal occurs on the latter and the cycle is repeated. The outer electrodes may be stationary and the central electrode resiliently mounted, Fig. 4 (not shown). The drive from the vibrator may comprise a pawl and ratchet mechanism or a transformer may convert the current surges produced by the condenser discharge into an alternating current.
Patent GB-1252415-A (GB)
IPC: B60R25/021
Filed: 1967-11-10
Abstract: 1,252,415. Locks. LOWE & FLETCHER Ltd. 3 Feb., 1969 [10 Nov., 1967], No. 51261/ 67. Heading E2A.  A motor vehicle anti theft device comprises a barrel lock in which one set of spring urged tumblers, When in their locking position, have locking portions 11a-11e projecting in a row from the barrel 10 at one side thereof, and another set of tumblers, when in their locking positions have locking portions 11f-11j projecting in a row from the opposite side of the barrel 10, each tumbler being operatively engageable with one or the other of two edge face portions at opposite edges on the proper key of the lock, so that the key can be inserted into the lock in either of two possible angular positions to displace the tumblers to their releasing positions, but the latter cannot be moved to their releasing positions by a key having a like profile along one edge face only corresponding to those presented by both edge faces of the proper key. As shown, each tumbler is an apertured plate the locking portion of which is engageable with one of a pair of grooves 9 at diametrically opposite sides of a housing 8 for the barrel. In another arrangement, the tumblers may be of the twopart pin type. The lock forms part of a body portion 20 of the device which is adapted to be secured to a steering column by means of a clamp 22 and includes a bolt 23 for cooperation with a slot or keyway in the rotatable shaft of the column, and also a switch unit 24, also operable by the lock, for controlling the ignition circuit of the vehicle. Specification 54951/ 68 is referred to.