baber/WOPTO huggingface dataset:
Patent IL-109691-A (IL)
Title: Rifamycin derivatives substituted in position 36 their preparation and pharmaceutical compositions containing them
Inventor: EMILIO OCCELLI
IPC: A61K31/395
Filed: 1994-05-19
Abstract: PCT No. PCT/EP94/01428 Sec. 371 Date Jan. 22, 1996 Sec. 102(e) Date Jan. 22, 1996 PCT Filed May 5, 1994 PCT Pub. No. WO94/28002 PCT Pub. Date Dec. 8, 1994   <IMAGE>  (1)   <IMAGE>  (I)   <IMAGE>  (Ia)  Rifamycin antibiotic derivatives of formulae (I) and (Ia) bearing at the position 36 a substituent selected from (C1-C8)alkyl, halo, hydroxy, (C1-C4)acyloxy, (C1-C4)alkoxy, (C1-C4)alkylthio, (C1-C4)alkylamino, di(C1-C4)alkylamino and substituted 4-oxo-3-pyridinyl carbonyloxy of formula (1) obtained by reacting rifamycin with suitably substituted malonic acid. The compounds of the invention are antimicrobial agents mainly active against gram positive bacteria and fastidious gram negative bacteria showing the considerable antimicrobial activity against the rifamypicin resistant microbial strains.
Patent IL-110059-A (IL)
Title: Fluid collection system
IPC: A61M39/10
Filed: 1994-06-20
Abstract: A patient fluid collection system is disclosed which includes a fluid collection reservoir, a cover for the reservoir and a liner within the reservoir comprising an enlargeable or expandable wall portion such that the wall portion may expand if the liner fills with fluid. An anti-reflux system is also disclosed as well as a new tandem tube and a new connector.
Patent IL-117047-A (IL)
Title: Method for purifying diacetylrhein for obtaining a diacetylrhein free of aloe-emodin
IPC: A61K31/22
Filed: 1996-02-06
Abstract: PCT No. PCT/IB96/00093 Sec. 371 Date Mar. 18, 1997 Sec. 102(e) Date Mar. 18, 1997 PCT Filed Feb. 7, 1996 PCT Pub. No. WO96/24572 PCT Pub. Date Aug. 15, 1996The present invention discloses a method for preparing purified diacetylrhein to be used in the preparation of drugs which includes the steps of: (a) suspending a diacetylrhein containing various impurities and, in particular, relatively high amounts of aloe-emodin derivatives, in a mixture of organic solvent/water; (b) adding a tertiary amine; (c) adding to the solution obtained a salt of an acid and of an alkali metal or of an alkaline-earth metal; (d) carrying out a hydrolysis in a weakly acidic medium; (e) collecting the purified diacetylrhein, by filtration.\!
Patent IL-133395-A (IL)
Title: Water-soluble chlorhexidine formulations
IPC: A61K47/26
Filed: 1999-12-09
Abstract: A chlorhexidine formulation in the form of a powdered, water-soluble mixture consisting of chlorhexidine base, one or more sugar acids or lactones thereof from the set gluconic acid or gluconolactone, lactobionic acid, D-galactono-g-lactone (II), L-mannono-g-lactone, D-(-)-gulono-g- lactone, D-(+)-galacturonic acid and a-D- heptaglucono-g-lactone, wherein the molar ratio of chlorhexidine base to sugar acid or lactone thereof is from 1 to greater than or equal to 2, and 0 to 10 wt.% of auxiliary substances.
Patent IL-148127-A (IL)
Title: Use of ramipril or pharmaceutical salt thereof for the preparation of a medicament for the prevention or reduction of a cardiovascular event in high risk patients with no evidence of left ventricular dysfunction
IPC: A61K/
Filed: 2002-02-12
Abstract: Use of an inhibitor of the renin-angiotensin system or a pharmaceutically acceptable derivative thereof, optionally together with an other antihypertensive, a cholesterol lowering agent, a diuretic or aspirin, in the manufacture of a medicament for the prevention of cardiovascular events; a method of preventing cardiovascular events comprising administering to a patient in need of such prevention an effective amount of an inhibitor of the renin angiotensin system or a pharmaceutically acceptable derivative thereof, optionally together with an other antihypertensive, a cholesterol lowering agent, a diuretic or aspirin; and a combination product containing an an inhibitor of the renin-angiotensin system or a pharmaceutically acceptable derivative thereof and a cholesterol lowering agent.
Patent IL-154529-A (IL)
Title: Antisense insulin-like growth factor binding protein (igfbp)-2-oligodeoxynucleotides for prostate and other endocrine tumor therapy
IPC: C07K14/47
Filed: 2003-02-18
Abstract: Compositions and a method are provided for the treatment of prostate and other endocrine tumors in mammals, including humans, by administration of an antisense oligodeoxynucleotide (ODN) which is complementary to a portion of the gene encoding IGFBP-2. Using the Shionogi tumor model in vitro and in vivo, the administration of such an ODN was shown to reduce proliferation of tumor cells, and also to delay the progression to androgen independence. Thus, treatment of prostate and other hormone-regulated cancer in mammals, including humans, and delay of the progression of prostate tumors to androgen independence is accomplished by administering to the mammal a therapeutically effective amount of an antisense oligodeoxynucleotide which is complementary to a portion of the nucleic acid sequence encoding IGFBP-2 and which reduces the amount of IGFBP-2 in the treated cells.
Patent IL-179532-A (IL)
Title: Quinazoline derivatives, pharmaceutical compositions comprising them and use thereof for the manufacture of medicaments for the treatment of pain or a gastrointestinal disorder
IPC: A61K31/505
Filed: 2006-11-23
Abstract: The present specification relates to the use of a quinazolinone compound of the formula (I) wherein R1, R2, R3, R4, R5 and m are as defined in the specification and in the claims, in free form or in salt form, and, where possible, in acid addition salt form.
Patent IL-192166-A (IL)
Title: Quantitative and qulitative analysis apparatus for measuring a body fluid
Inventor: KYOUNG-HUN KIM
IPC: A61B/
Filed: 2008-06-15
Abstract: A quantitative and qualitative analysis apparatus of a body fluid serves as a replacement of a Foley catheter and a urine bag connected The analysis apparatus is capable of automatically measuring the volume of a body fluid (urine volume) and specific constituents in a body fluid (urine and blood) in a real time mode and is capable of outputting the measurement results with ease, thereby promoting the efficiency of human resource management so that medical staff may be able to make a quick diagnosis on the current state of the patient based on the provided data and thus, take all necessary measured to improve the patient's condition at proper time.
Patent IL-196920-A (IL)
Title: Combination of anti-cs1 antibody and dexamethason for the treatment of multiple myeloma
IPC: A61K33/243
Filed: 2009-02-05
Abstract: Compositions and methods for treating MM are provided herein.
Patent JP-H10290143-A (JP)
Title: Low power consumption type storage circuit
Inventor: OKABE TOSHIHIRO
IPC: H03K3/037
Filed: 1997-04-17
Abstract: PROBLEM TO BE SOLVED: To provide the storage circuit for a flip-flop or the like in a semiconductor integrated circuit where the operation of a clock generating gate in the flip-flop is suppressed when a storage content and data to be entered newly are identical so as to reduce dynamic power consumption. SOLUTION: The circuit is provided with an EOR gate 4 that compares an output of a flip-flop circuit 1 with new data input and with an AND gate 5 that controls whether or not a clock signal is given to the flip-flop circuit 1 based on an output of the EOR gate 4, and only when the content already stored and data to be entered newly are identical, the clock input is invalidated and only when both the data are dissident, the clock input is validated.
Patent JP-S62256505-A (JP)
Title: Voltage/current converting circuit
Inventor: ARIMURA KENICHI
IPC: H03F3/34
Filed: 1986-04-30
Abstract: PURPOSE:To decrease generation of defective electronic circuits in manufacturing them by controlling the conversion ratio of an output current to an input voltage through the change in the current ratio of the 1st current by a shunt means thereby simplifying the resistance adjustment of an emitter resistor. CONSTITUTION:A single emitter resistor 5 is connected to an emitter of a conversion transistor (TR) 1 and its collector current IC flows through a TR 60 of a current mirror circuit 6 comprising TRs 60-62. The 1st current 11 from the TRs 61, 62 and the 2nd current 12 are proportional to the collector current IC and the 1st current 11 is injected to the emitter resistor 5 via a diode 7. A TR 8 branches all the 1st injected current to the emitter resistor 5 when the TR 8 is turned on by a switching signal SS. Since the collector current ratio of the two TRs 60, 61, that is, the ratio of the surrounding length of the collector region decides the switching width of the voltage/current converting ratio or its ratio, the control is attained very accurately.
Patent JP-S61257854-A (JP)
Title: Paper passing device
Inventor: KAJIURA TAKEO
IPC: B65B41/16
Filed: 1985-05-10
Abstract: PURPOSE:To considerably simplify labor for passing paper by mounting a retaining means for transporting paper at one end of a roller chain, and engaging a chain pulley with the chain. CONSTITUTION:A bush portion 18 of a roller chain 17 is slidably retained by guide rails 10 or 11 A chain pulley 15 is engaged with the roller chain at a certain place. By rotating an electric motor 16 where the chain pulley 15 is fitted, the roller chain 17 is slid and moved along guide rails 10, 11, 12, 13. Accordingly, in case of passing paper, a web transport bar 14 is moved from a standby position 14b to a position 14a to pass the paper from the position 14a to the position 14b. At the completion of passing paper, the web transport bar is returned to the standby position 14b.
Patent JP-H02279397-A (JP)
Title: Method for initializing writing brush drawing apparatus
Inventor: SHIMIZU HIROAKI
IPC: B43L13/00
Filed: 1989-04-21
Abstract: PURPOSE:To drive the drive device of a writing brush drawing apparatus running into a non-drivable state caused by the meshing of a lead screw with a vibration pin by vibrating the drive part and movable part of the writing brush drawing apparatus in initialization. CONSTITUTION:In a case performing initialization, when a drive device (c) begins to drive by an initialization control means (f) and the output of a detection means (d) becomes active, initialization is regarded to be completed. In such a case that the output of the detection means (d) is inactive as it is, operation is not completed at this time, and a drive part and a movable part are vibrated on the basis of the instruction of the initialization control means (f) by an exciting means (g) and, thereafter, the initialization is again performed. By this method, even a mechanism wherein the drive device (c) becomes impossible to drive because of high load at the first time and initialization is not completed becomes easy to initialize.
Patent JP-S5326520-A (JP)
Title: Image pickup equipment
Inventor: TERAOKA SANEMITSU
IPC: H04N5/235
Filed: 1976-08-24
Abstract: PURPOSE: By obtaining the primary and secondary electric images via the pricmary and secondary optical filters, the pickup equipment is obtained which can reproduce both the high-brightness part and dark part excellently against a subject having a large contrast rate, thereby utilizing it in an ironworks, etc. 
     COPYRIGHT: (C)1978,JPO&Japio
Patent JP-2000290785-A (JP)
Title: Al-containing film-coated member and its production
Inventor: HARADA YOSHIO
IPC: C23C28/02
Filed: 1999-04-07
Abstract: PROBLEM TO BE SOLVED: To modify an Al-contg. sprayed coating excellent in corrosion resis tance and to improve its wear resistance by laminating an Ni base undercoat and an Al topcoat on the surface of a base material by a thermal spraying, executing a heating treatment and dispersedly precipitating an Ni-Al intermetallic compd. into the composite film. SOLUTION: On the surface of a base material made of metal or inorganic nonmetal, an undercoat of Ni or the alloy thereof and a topcoat of Al or the alloy thereof are laminated by a thermal spraying method, and, if required, this is laminated by >= two layers as well to form a composite film. This film may be formed by a CVD method, a PVD method, a plating method, a cementation method, a mechanical alloying method or the like. Next, the composite film is heated to a temp. equal to or above the m.p. of the metal for the topcoat. In this way, Ni and Al in the composite film are brought into alloying reaction, and hard Ni-Al intermetallic compds. such as Ni3Al, NiAl, Ni2Al3, NiAl3 and Ni2Al3 are finely precipitated to modify the structure of the soft Al-contg. film.
Patent JP-H06305571-A (JP)
Title: Long scaled object sorter
Inventor: EKAGO NORIAKI
IPC: B65G59/02
Filed: 1993-04-27
Abstract: PURPOSE:To provide a means capable of solving at a stroke various problems in the past such that a long scaled object can not be sorted according to its kind and deformed condition with great labor required in bad efficiency, in a sorter for sorting from a large number of the long scaled objects to a small number thereof loaded on a loading base. CONSTITUTION:A device has a lift means R formed by liftably constituting a holding part 5 of removably holding one end part of a small number of long scaled objects L and a receiving stop tool 8 for receiving an intermediate part of small number of the long scaled objects L, in a condition that the one end part is lifted by this lift means R, supported from below. Further the device has a moving means 9 for moving this receiving stop means 8 in the lengthwise direction of the long scaled object and a thrust up means 10 for intermittently pushing up the other end side part of a large number of the long scaled objects L loaded on a loading base 1.
Patent JP-2000289993-A (JP)
Title: Screw jack for vehicle
Inventor: SEKIGUCHI TOSHIO
IPC: B66F3/10
Filed: 1999-04-07
Abstract: PROBLEM TO BE SOLVED: To attain a mass production and a lower cost by forming a tooth hole part and a cylindrical boss part on a large gear by press cutting and molding of a steel plate, cutting a connecting female thread in the cylindrical boss part, screwing it to the connecting male thread of a main shaft screw bar, and integrating the upper end of the cylindrical boss part to the circumference of the main shaft screw bar by spot welding. SOLUTION: A large gear 8 is formed by circular press cutting a steel plate are forming a gear hole thereon. A cylindrical boss part 8c protruding upward and an upper half connecting surface for a thrust ball bearing 6 are press molded in the center of the circular plate part. A connecting female screw part 8c1 is cut in the cylindrical boss part 8c. On the other hand, a connecting male thread 10a is cut on the lower end thread part circumference of a main shaft screw bar 10. The connecting male thread 10a of the main shaft screw bar 10 is screwed to the connecting female thread 8c1 of the cylindrical boss part 8c of the large gear 8, and the upper end of the cylindrical boss part 8c is spot welded to the circumferential surface of the main shaft screw bar 10 to integrally fix the large gear 8 to the main shaft screw bar 10.
Patent JP-H04332519-A (JP)
Title: Dust collection quantity display device of cleaner
Inventor: YOSHIKAWA TATSUO
IPC: A47L9/19
Filed: 1991-05-02
Abstract: PURPOSE:To appropriately grasp the dust collection quantity by a compact and inexpensive structure by providing a heating element, an air cooling part for cooling this element, and a display part of a temperature of the heating element, and constituting the device so that an air flow rate of the air cooling part depends on suction force of the cleaner main body. CONSTITUTION:By a suction operation, a driving motor 8 of a rotary brush 7 is self-heated, but cooled by cooling air which goes in from a ventilating hole 15, and its temperature rise is suppressed to <=alpha deg.C prescribed value. However, when the accumulation quantity of a dust collecting chamber increases and becomes full, air resistance becomes large and a suction flow rate falls. Therefore, a flow rate of cooling air also falls and a temperature of the driving motor 8 rises and becomes a high temperature beta deg.C. In this case, a discoloration critical temperature gamma deg.C of a liquid crystal 17 is set in advance so as to become alpha deg.C<gamma deg.C<=beta deg.C by an experiment, etc. In such a way, with respect to a temperature variation of the driving motor 8 caused by an increase of the dust collection quantity, the liquid crystal 17 displays it by its color variation and informs the dust collection quantity.
Patent JP-H0680621-A (JP)
Title: New benzylenol ether derivative and plant protectant/ bactericide
Inventor: HORUSUTO BUINGERUTO
IPC: C07C69/738
Filed: 1993-04-27
Abstract: Benzyl enol ether derivatives of the formula I <IMAGE>  in which   A denotes CH2, CHCl, CH-alkyl, CH-O-alkyl, CH-S-alkyl, N-O-alkyl and     B denotes OH, alkoxy, alkylthio and alkylamino, U, V and W are identical or different and denote hydrogen, halogen, alkyl and alkoxy, R<1>, R<2> and R<3> are identical or different and denote hydrogen, cyano, halogen, amino, ester, amide, acyl, S(O)nR<4>, PO(OR<4>)2, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, cycloalkyl-alkyl, alkoxy-alkyl, alkylthio-alkyl, arylthio-alkyl, alkenyl, haloalkenyl, cycloalkenyl, halocycloalkenyl, alkynyl, alkoxy, haloalkoxy, alkylthio, benzylthio, alkylcarbonyl, optionally substituted phenylcarbonyl, optionally substituted benzylcarbonyl, alkoxycarbonyl, optionally substituted phenoxycarbonyl, optionally substituted benzyloxycarbonyl, optionally substituted aryl, optionally substituted aryloxy, optionally substituted arylthio, optionally substituted arylalkyl, optionally substituted arylalkenyl, optionally substituted aryloxyalkyl, optionally substituted arylthioalkyl, optionally substituted hetaryl, optionally substituted hetaryloxy, optionally substituted hetarylthio, optionally substituted heteroarylalkyl, optionally substituted hetarylalkenyl, optionally substituted hetaryloxyalkyl, optionally substituted heterocyclyl and optionally substituted heterocyclyloxy, and   the radical R<4> denotes hydrogen and C1-C4-alkyl, and R<1> and R<3> together and also R<2> and R<3> together can in each case form a carbocyclic or heterocyclic ring which, in turn, can be benzo-fused and substituted, and fungicides containing these compounds.
Patent JP-H03296659-A (JP)
Title: Analysis of carbon monoxide in gas
Inventor: NAKAYASU TOSHIHIRO
IPC: G01N33/00
Filed: 1990-04-17
Abstract: PURPOSE:To enhance the detection sensitivity of CO by converting carbon monoxide CO in gas to be analyzed to carbon dioxide CO2 using metal oxide and analyzing CO2 by mass spectrometry (MS). CONSTITUTION:A definite amount of purified nitrogen N2 gas 6 is introduced into an atmospheric ionizing mass analyser 9 through a reaction furnace 1 and, next, a definite amount of CO standard gas is introduced into the analyser 9. At this time, granular copper oxide having particle size of about 14 - 28 mesh is previously heated at 350 deg.C for about 240 hr in nitrogen gas as metal oxide 1c before use. The ratio of the N2 gas 6 and the CO standard gas 8 is changed to prepare a calibration curve of CO. Next, a definite amount of sample gas 7 is introduced into the analyser 9 without being passed through the reaction furnace 1 to measure relative ion strength (a) and the content of CO2 is measured by this operation. Subsequently, the gas 7 is passed through the reaction furnace 1 to be introduced into the analyser 9 to measure the relative ion strength (b) of CO2 and the ion strength value (a) is subtracted from the value (b) and the obtained value is substituted for the previously calculated calibration curve to detect the concn. of CO in the gas 7.
Patent JP-H09285294-A (JP)
Title: Production of l-glutamic acid by fermentation
Inventor: ONO EIJI
IPC: C12P13/14
Filed: 1996-04-23
Abstract: PROBLEM TO BE SOLVED: To efficiently obtain L-glutamic acid useful in foods, medicines, etc., by culturing a bacterium belonging to the genus Escherichia, having resistance to aspartic acid metabolism antagonist, capable of producing L-glutamic acid in a medium and collecting the product in the culture solution. SOLUTION: A new bacterium [e.g. Escherichia coli AJ 13,199 (FERM P-15,573), etc.] belonging to the genus Escherichia, having resistance to a aspartic acid metabolism antagonist such as aspartic acid β-hydroxamate, capable of producing L-glutamic acid is cultured in a liquid medium. L-Glutamic acid is formed and accumulated in the culture solution and collected to give the objective L-glutamic acid important in foods, medicines, etc., by fermentation in improved productivity inexpensively and efficiently.
Patent JP-H0228114-A (JP)
Title: Remedy for nephritis
Inventor: NISHII YASUHO
IPC: A61P15/00
Filed: 1989-04-20
Abstract: PURPOSE:To obtain a remedy for glomerulonephritis, containing 22- oxa-1alpha,25-(OH)2D3 as an active ingredient, having inhibitory effects on urinary protein secretion and effective against especially chronic glomerulonephritis with hardly any side effects. CONSTITUTION:The objective substance obtained by containing 1alpha,3beta-hydroxy20alpha-(3-hydroxy-3-methylbutyloxy)-9,10-seco-5,7 ,10(19)-pregnatriene [hereinafter abbreviated to 22-oxa-1alpha,25-(OH)2D3] as an active ingredient and formulating a pharmaceutical according to a conventional method. The substance can be prepared in the form of tablet, capsule, granule, injection, etc., and the dose thereof is 0.01-10mug per day for an adult. The 22-oxa-1alpha,25-(OH)2D3 is synthesized from 1alpha,3beta-dihydroxy-5,7-pregnadien-20alpha-ol as a starting material by a well- known method.
Patent JP-S62258113-A (JP)
Title: Exhaust device for vehicle
Inventor: MORITA TOSHIMASA
IPC: B62K5/00
Filed: 1986-05-02
Abstract: PURPOSE:To ensure an exhaust expansion pipe of a sufficiently large volume in a vehicle equiped with a saddle type driver's seat by providing the exhaust expansion pipe which makes at least one turn along a vertical plane in the longitudinal direction of a vehicle body. CONSTITUTION:A four wheel vehicle for running on ungraded roads has an engine, for example, a two cycle two cylinder engine 60 mounted on near the center of a vehicle body wherein each exhaust port of cylinders is opened directing obliquely forward down out of a right and a left down-tube 34 in front of the cylinders. A pair of a right and a left exhaust expansion pipe 68 is connected with the engine 60 at its each exhaust port of the cylinders wherein each expansion pipe 68 is formed in such a way that it extends obliquely forward down out of the right and left down-tubes 34, enters between a right and a left front wheel 42, rises upward between the engine 60 and a travelling shaft 44, and then makes a spiral turn toward the side of the vehicle body while making one turn in the longitudinal direction of the vehicle body along a vertical plane. This constitution makes it possible to enlarge the volume of the exhaust expansion pipe thereby attempting a reduction in back pressure.
Patent JP-H05296248-A (JP)
Title: Slider member
Inventor: KATAYAMA TETSUYA
IPC: F16C33/24
Filed: 1992-04-21
Abstract: PURPOSE:To provide a slider member of excellent abrasion resistance and low friction having a sliding surface comprising a thin film so formed to cover the surface of a ceramics-containing member by setting below a specific value the maximum difference in height among the irregularities of the surface of the member. CONSTITUTION:The maximum difference Rmax in height among the irregularities of the surface of a slider member is not more than 0.8mum. The overall surface of the member can then be covered without exposing the member even with small film thickness. Because the surface of the member is not exposed, it is not directly exerted with loads by disturbance and so does not easily peel off. For example, the combined bearing body 50 of a rotating polygon mirror comprises a stator 22 and a rotor 21, both of which are rotatable via a predetermined clearance therebetween. The stator 22 is made by using Si3N4 ceramics as its base material and forming a DLC(diamond-like carbon) film on the surface of the base material. The maximum value Rmax of the surface roughness of the DLC film is not more than 0.8mum.