baber/WOPTO huggingface dataset:
Patent CA-2539314-A1 (CA)
Title: Thiazolopyridine derivatives as adenosine receptor ligands
Inventor: NORCROSS ROGER DAVID
IPC: A61K31/4353
Filed: 2004-09-11
Abstract: The present invention relates to compounds of the general formula (I) wherein R1 is morpholin-4-yl, phenyl or tetrahydropyran-4-yl; R2 is -(CH2)n-aryl, unsubstituted or substituted by one or more substituents, selected from the group consisting of halogen, lower alkoxy, lower alkyl, -(CH2)n NR~R", -0 (CH2)n-O -lower alkyl, or -(CH2)n-heterocyclyl, or is heteroaryl, unsubstituted or substituted by one or more substituents, selected from the group consisting of lower alkyl, lower alkoxy, -(CH2)n NR'R", -(CH2)n-heterocyclyl, which is optionally substituted by hydroxy or lower alkoxy, or is -(CH2)n-heterocyclyl, optionally substituted by one or more substituents selected from the group consisting of -(CH2)n,-OH, -(CH2)n-O-lower alkyl or lower alkyl, or is -(CH2)n-cycloalkyl, or is - (CH2)n,-O -lower alkyl, or is NR'R~~, or is benzo[1,3]dioxole, 2-methyl-l-oxo-2,8-diaza-spiro[4,5] decane, 2-oxa-5-aza~bicyclo [2.2.1]heptane or I-oxa-8-aza-spiro[4.5]decane; R',R" are independently from each other lower alkyl, - (CH2)n ,-O -lower alkyl or cycloalkyl, optionally substituted by hydroxy; n is 0, 1 or 2; and to pharmaceutically acceptable acid addition salts thereof. These compounds may be used in the control or prevention of illnesses based on the modulation of the adenosine system, such as Alzheimer's disease, Parkinson's disease, Huntington's disease, neuroprotection, schizophrenia, anxiety, pain, respiration deficits, depression, drug addiction, such as amphetamine, cocaine, opioids, ethanol, nicotine, cannabinoids, or against asthma, allergic responses, hypoxia, ischaernia, seizure and substance abuse. Furthermore, compounds of the present invention may be useful as sedatives, muscle relaxants, antipsychotics, antiepileptics, anticonvulsants and cardiaprotective agents for disorders such as coronary artery disease and heart failure. The most preferred indications in accordance with the present invention are those which include disorders of the central nervous system, for example the treatment or prevention of Alzheimer's disease, certain depressive disorders, drug addiction, neuroprotection and Parkinson's disease as well as ADHD.
Patent CA-2540560-A1 (CA)
Title: Solid-liquid separation of oil-based muds
Inventor: MASIAS HENRY
IPC: C09K23/52
Filed: 2004-07-16
Abstract: This invention relates to a method of achieving a solid-liquid separation of an oil-~based mud comprising the step of contacting said oil-based mud with a water-in-oil emulsion comprising a polymer derived from at least one water-soluble monomer, where the polymer is not dissolved prior to contact with the oil-based mud, mixing the water-in-oil emulsion and the oil-based mud and separating the solid phase from the liquid phase in the oil-based mud. In addition, this invention also relates to a composition comprising an oil-based mud with a water-in-oil emulsion comprising a polymer derived from at least one water-soluble monomer, wherein the polymer is not dissolved prior to contact with the oil-based mud.
Patent CA-2542570-A1 (CA)
Title: Chop saw
Inventor: MEREDITH DARYL S
IPC: B27B5/29
Filed: 2006-04-11
Abstract: A chop saw having a base assembly, a saw assembly pivotally attached to the base assembly for movement between an upper position and a lower position, the saw assembly including a motor, a blade driven by the motor, an upper blade guard covering an upper part of the blade, and a laser assembly disposed on the saw assembly.  The laser assembly may include a housing attached to the saw assembly, a rail supported by the housing, a body slidingly disposed on the rail, a holder pivotally attached to the body, a laser diode pivotally disposed on the body for emitting a laser beam along a first path, and a line lens disposed in the first path for converting the laser beam into a laser plane projected towards the base assembly.
Patent CA-2545043-A1 (CA)
Inventor: DE BRAUD FLIPPO
IPC: A61K31/704
Filed: 2004-11-12
Abstract: Methods of treating a human body for cancer are provided. In one aspect, a therapeutic amount of doxorubicin is administered in combination with ET-743 in a dose range between 0.5 and 1 mg/m2. In a related aspect, an effective therapeutic amount of ET-743 is administered in combination with doxorubicin in a dose range between 40 and 80 mg/m2.
Patent CA-2550843-A1 (CA)
Inventor: TANABE ITSUYA
IPC: A61P37/08
Filed: 2004-12-22
Abstract: A specific phenylalanine derivative or its analog showing an activity of inhibiting .alpha.4 inntegrin is used as a remedy for various diseases in which .alpha.4 inntegrin participates.
Patent CA-2552863-A1 (CA)
Title: Multilumen catheters and methods for their use
Inventor: CONSTANTZ BRENT R
IPC: A61F2/958
Filed: 2005-01-07
Abstract: Multilumen aspiration and delivery catheters, as well as methods for their use, are provided. The subject multilumen catheters include a proximal end and a distal end separated by a non-coaxial multilumen tube. Also provided are systems for use in flushing a vascular site with fluid, usually at least two different fluids, where the subject systems are made up of a delivery catheter inside of an aspiration catheter. In addition, kits comprising various components of the subject systems, e.g., at least two different multilumen catheters, are provided. The subject multilumen aspiration and delivery catheters, systems and kits find use in a variety of different applications in which it is desired to flush a vascular site with at least one and preferably two different fluids, where particular applications of interest include the treatment of vascular lesions.
Patent CA-2552918-A1 (CA)
Title: Gossypol derivatives, production method thereof and uses of same
Inventor: MICHELOT ROBERT
IPC: A61K31/10
Filed: 2005-01-06
Abstract: Gossypol derivatives (I) are new. Gossypol derivatives of formula (I) are new. R 1, R 2= OH, CH 2OR 3, CH 2SR 3or CH 2NR 3R 4; R 3-R 6= H or 1-10C optionally unsaturated groups optionally substituted with heteroatomic groups. Independent claims are also included for two processes for preparing (I). [Image] ACTIVITY : Cytostatic; Protozoacide; Virucide; Immunosuppressive. 2,2'-bis(6,7,8-trihydroxy-5-isopropyl-3-methyl-1,4-naphthoquinone) had IC 50of 1 mu M against KB tumor cells. MECHANISM OF ACTION : Protein kinase inhibitor. 2,2'-bis(6,7,8-trihydroxy-5-isopropyl-3-methyl-1,4-naphthoquinone) gave 96% inhibition of SGk protein kinase at a concentration of 10 mu M.
Patent CA-2553679-A1 (CA)
Title: Hmgb1 protein inhibitors for the regulation of smooth muscle cells and endothelial cells profileration
Inventor: BIANCHI MARCO E
IPC: C07K16/18
Filed: 2005-01-26
Abstract: The use of molecules that modulate the action of HMGB1 protein (or molecules having sequence homology) for the preparation of therapeutic agents for the treatment of diseases to related to endothelial and smooth muscle cells proliferation; said proliferation can be due to endothelium damage, caused by surgical operation and manipulation made on or through blood vessels, including coronary and/or carotid angioplasty, angiographic surgery, and surgery using catheters.
Patent CA-2555325-A1 (CA)
Inventor: MUNTERMANN AXEL
IPC: A61N2/02
Filed: 2005-02-04
Abstract: The invention concerns a device for therapeutically treating a patient using magnetic fields, particularly with nuclear magnetic resonances. The aim of the invention is to provide a device for treating a patient using magnetic fields, with which, in particular, a localized treatment, e.g. in the head area of the patient is made possible, which burdens the patient as little as possible, and which can be used in a space-saving manner. The device should also be able to be versatilely adapted to the anatomy of the patient and/or to the clinical picture. According to the invention, the device has a backrest and at least one first extension member (4B), which projects from the plane defined by the backrest (1C), and a device (30B) for generating the first magnetic treatment field is mounted on the first extension member (4B). In a particularly preferred embodiment, the device is provided in the form of a treatment seat or chair.
Patent CA-2556668-A1 (CA)
Title: Method and apparatus for controlling a battery
Inventor: JACOBS JAMES K
IPC: H02J7/00
Filed: 2004-06-22
Abstract: A battery controller for charging and discharging a plurality of batteries is disclosed. The battery controller has a plurality of direct current to direct current (DC to DC) converters connected to each other in series. Each battery of a plurality of batteries is electrically connectable to a respective DC to DC converter. A co-ordinator connected to each of the plurality of DC to DC  converters controls charging and discharging of the battery electrically connected to the respective converter. The co-ordinator can also control charging and discharging of any one of the batteries to ensure that the battery retains sufficient electrical capacity, and, to increase the longevity of the respective batteries. Because each battery is electrically connected to a respective DC to DC converter, the energy from one battery can be used to charge another battery in order to monitor battery characteristics including energy capacity of each battery. Each of the DC to DC converters is selected to operate preferably below 30 volts while the total voltage of the entire battery system can be much more than 30 volts depending on the number of DC to DC converters placed in series.
Patent CA-2557547-A1 (CA)
Inventor: WILLIAMS WILLIAM
IPC: C07D221/18
Filed: 2005-02-25
Abstract: The present invention relates to Isoquinoline Derivatives, compositions comprising an effective amount of a Isoquinoline Derivative and methods for treating or preventing an inflammatory disease, a reperfusion injury, an ischemic condition, renal failure, diabetes, a diabetic complication, a vascular disease other than a cardiovascular disease, cardiovascular disease, reoxygenation injury resulting from organ transplantation, Parkinson's disease, or cancer, comprising administering to an animal in need thereof an effective amount of a Isoquinoline Derivative.
Patent CA-2559039-A1 (CA)
Title: Apparatus and method for boosting sound in a denta-mandibular sound-transmitting entertainment toothbrush
Inventor: CAPPER DAVID G
IPC: A61H7/00
Filed: 2005-11-30
Abstract: A device and method for transmitting sound waves between a signal source and a user's ears, wherein the sound waves bypass the air. The sound waves are conducted by the user's teeth and bones to the user's ears, where they are perceived as sound. Sound~transmitting toothbrushes and the like are described to transmit and/ or conduct sound to the user's ear, while the user is brushing his or her teeth. The toothbrush head and a signal source are configured to produce sound waves for transmission through the toothbrush head to the user's mouth, and a tension controller is configured to control the volume of the sound waves based on the pressure applied by the toothbrush head. The signal source may produce sound waves directly or with the assistance of a transducer. The signal source may be replaceable, connect to a replaceable cartridge, or connect to an adaptor capable of downloading data to allow the signal source data to be replaceable. The tension controller may include gap spacing between the transducer coil and transducer plate. The tension controller may also include a boost switch configured as a bypass switch, activation signal, or force sensor.
Patent CA-2559121-A1 (CA)
Title: Bulk solidified quenched material and process for producing the same
Inventor: FURUYA YASUBUMI
IPC: H01L41/47
Filed: 2004-10-08
Abstract: [PROBLEMS] To obtain a material in bulk form suitable for use as a material of actuator or sensor element from a Ti-Ni base shape memory alloy or Fe-Ga base magnetostrictive alloy taking advantage of crystal miniaturization and anisotropy as well as reduction of precipitates (= equilibrium phase in state diagram) and nonequilibrium phases peculiar to liquid quenched solidified materials, and to attain performance enhancement by a production process superior in cost to the melt process. [MEANS FOR SOLVING PROBLEMS] Given quenched solidified structure of a Ti-Ni base shape memory alloy or Fe-Ga magnetostrictive alloy, or quenched material with properties according thereto is sliced into thin pieces and piled in multilayer form in a die, or alternatively powder or chops thereof are charged in a die, followed by high-density bonding according to an electric discharge sintering method to thereby obtain an alloy in bulk form. Optionally, the sintering is further followed by annealing of the alloy in bulk form. Thus, the performance of the alloy is enhanced.
Patent CA-2560281-A1 (CA)
Title: Model based distortion reduction for power amplifiers
Inventor: BATRUNI ROY G
IPC: H03F1/26
Filed: 2005-03-24
Abstract: A method of processing a signal is disclosed. The method comprises generating a digital signal, converting the digital signal to an analog signal, and generating an amplified analog signal having distortions. The method further comprises converting the amplified analog signal to a feedback digital signal at a sample rate and' updating a model of the distortions based on the feedback digital signal.
Patent CA-2562040-A1 (CA)
Title: Procede et dispositif d'injection automatique par jet dans des oeufs d'oiseux
Inventor: KARACA KEMAL
IPC: A01K45/00
Filed: 2005-04-01
Abstract: L'invention concerne un dispositif de jet par injection in ovo et des procédés connexes de traitement des oeufs d'oiseaux. Le dispositif comprend un ou plusieurs appareils d'injection permettant de fournir une ou plusieurs substances de traitement dans des parties préétablies des oeufs, sous flux haute pression. On peut ainsi délivrer plusieurs substances en séparation spatiale et/ou temporelle, et assurer l'utilisation efficace de ces substances, y compris les substances efficaces en utilisation séparée mais nocives en utilisation mélangée. L'injection dans des oeufs embryonnés réduit les risques de blessure mécanique sur les poussins naissants, contrairement à une injection par seringue. On peut enfin réduire de la sorte les risques d'infections.
Patent CA-2562742-A1 (CA)
Inventor: PALANTI ROBERT C
IPC: B61L15/00
Filed: 2005-04-26
Abstract: A distributed power train (10) communications system for sending and receiving signals between a lead locomotive (14) and remote locomotives (12A/12B/12C) in the train (10). A lead (14) initiated message is received by at least the remote locomotive (12A/12B) nearest to the lead unit (14). The receiving remote unit (12A/12B) retransmits the message for receiving by the next remote unit (12C) in the train. Thus the message leapfrogs down the train from the lead unit (14) to the remote units (12A/12B/12C). When the last remote unit (the nth remote unit) (12C) receives the message, the last remote (12C) transmits a status or other response message to the lead unit's message. The status message is received at the (n-1)th remote unit (12A/12B), which appends its status message and transmits the combined status messages toward the lead unit (14). Each successive remote unit receives the status messages of the other remote units and appends its status message, until the concatenated status message reaches the lead unit (14).
Patent CA-2563063-A1 (CA)
Title: Purification of progesterone receptor modulators
Inventor: WILK BOGDAN KAZIMIERZ
IPC: A61K31/538
Filed: 2005-04-25
Abstract: Methods for purifying a compound of formula I are provided, wherein A, B, X, Q, and R1 are defined herein. The methods include mixing the compound of formula I and a. solvent; adding a base to the solvent; and precipitating purified compound of formula, I.
Patent CA-2563786-A1 (CA)
Title: Tools for stacking uncoordinated software projects
Inventor: COPE ROD
IPC: G06Q10/00
Filed: 2005-04-28
Abstract: A tool is provided for addressing a number of issues related to assembling software stacks (504C) including multiple uncoordinated components such s open source projects. The tool identifies individual projects (504A) for stacking, manages dependency relationships and provides an intuitive graphical interface (508) to assist a user. A project filter is also provided for controlling access to or installation of projects in accordance with filter criteria. In this manner, compliance with internal policies regarding the use of open source or other software is facilitated.
Patent CA-2565566-A1 (CA)
Inventor: MCCLANAHAN TERRILL K
IPC: C12Q1/68
Filed: 2005-05-02
Abstract: Provided are methods for diagnosing the propensity of a subject to develop skin inflammation, in particular, psoriasis. Also provided are methods of treatment with antagonists of IL-17 and/or IL-23.
Patent CA-2565739-A1 (CA)
Inventor: NICOLA ANTONIO PIETRO
IPC: B01J31/28
Filed: 2006-10-26
Abstract: Alkadienes may be telomerized in the presence of a heterogeneous catalyst comprising an alumina or titania support which is modified with one or more ionic complexes of Pd or Pt and activated at a temperature from 450°C to 850°C for a time not less than two hours. The resulting telomere may be useful in a number of applications.
Patent CA-2567409-A1 (CA)
Inventor: OCHI YASUSHI
IPC: A63D1/00
Filed: 2005-05-19
Abstract: A bowling game apparatus allowing even children whose ball throwing directions are not fixed to obtain high score by strikes and spares. The bowling game apparatus (1) comprises two guide members (10) installed in the longitudinal direction of a lane (3), two first holding bodies (15) disposed on the outside of the approach (2) side end part of the lane (3) and holding one ends of the guide members (10), two second holding bodies (20) installed, parallel with each other, above the lane between the first holding bodies (15) and a pin (5) group, holding the other ends of the guide members (10), and having other end holding parts movable between the guide positions and retrieval positions apart from the guide positions, and a second holding body drive means moving the other end holding parts of the second holding bodies (20) between the retrieval positions and the guide positions. The guide members (10) are so disposed that, when the other holding parts of the second holding bodies (20) are at the guide positions, they are crossed diagonally with the longitudinal direction of the lane (3) and brought into contact with a ball rolling on the lane (3) at the vertical center of the ball.
Patent CA-2567684-A1 (CA)
Title: Composition in the form of a spray comprising a combination of clobetasol propionate and calcitriol, an alcohol phase and an oily phase
Inventor: WILLCOX NATHALIE
IPC: A61K47/44
Filed: 2005-06-15
Abstract: The invention relates to an anhydrous composition in the form of a spray comprising a combination of clobetasol propionate and calcitriol as pharmaceutical active ingredient, an alcohol phase and an oily phase in a physiologically acceptable medium, to the process for its preparation and to its use in cosmetics and dermatology.
Patent CA-2569945-A1 (CA)
Title: System and method for managing network traffic load upon outage of a network node
Inventor: HOSSAIN ASIF
IPC: H04L69/40
Filed: 2006-12-01
Abstract: In one embodiment, a scheme is disclosed for managing network traffic load upon outage of a network node (304A) disposed in a wireless packet data network (300), wherein the network node (304A) is adapted to serve a substantially large number of mobile nodes (102) using respective data connections. Upon encountering an outage-causing condition (404), the network node (304A) releases the data connections and determines to suppress generation of session termination messages (406) that would have otherwise been generated for transmission to the mobile nodes (102).
Patent CA-2570120-A1 (CA)
Title: Passenger seat belt indicator
Inventor: PHILLIPS SUZANNE
IPC: B60Q9/00
Filed: 2006-02-03
Abstract: Everyday Children sustain serious injuries and die in crashes. Many of these injuries and deaths can be avoided with the correct use of child safety seat, and boosters and most of all the scat belt which is the main restraint for keeping these effective. Many Safety experts believe between 80% to 90% of child safety seats and belts, are installed and / or used incorrectly. Our children are at risk. In Passenger vehicles many drivers or parents are unaware that the safety car seat, booster or child is no longer buckled in, there by placing their child at great risk.  Although the back seat is considered the safest place for our infant seats and our children to be buckled in, this is still considered a blind spot to the drive or parent especially while driving, most parents or drivers are usually not aware until it becomes too late.
Patent CA-2570677-A1 (CA)
Title: Method and apparatus for scaling selected areas of a graphics display
Inventor: WANG YEQING
IPC: G06T3/40
Filed: 2006-12-11
Abstract: A method (30) and apparatus (10) for scaling selected areas of a graphics display. The method (30) includes removing distortion-sensitive information from the graphics display, scaling or converting the format of the distortion-nonsensitive information, such as from one aspect ratio to another, and then compositing the removed distortion-sensitive information with the scaled distortion-sensitive information. Alternatively, the removed distortion-sensitive is scaled, distortion-free, before combining it with the scaled distortion-nonsensitive information. The apparatus (10) uses a recognition comparator (16) to identify distortion-sensitive information, a graphics remover (18) to remove the distortion-sensitive information, a first scaler (22) to scale the distortion-nonsensitive information, a second scaler to provide distortion-free scaling of the distortion-sensitive information, and a compositer (26) to combine the distortion-sensitive information with the scaled distortion-nonsensitive information. A graphics display can be converted using a conversion process that introduces distortion, yet distortion-sensitive information, such as logos, are not subject to such distortion.
Patent CA-2573292-A1 (CA)
Inventor: MOUSSOURIS JOHN
IPC: G06F17/50
Filed: 2004-07-12
Abstract: A programmable processor and method for improving the performance of processors by expanding at least two source operands, or a source and a result operand, to a width greater than the width of either the general purpose register or the data path width. The present invention provides operands which are substantially larger than the data path width of the processor by using the contents of a general purpose register to specify a memory address at which a plurality of data path widths of data can be read or written, as well as the size and shape of the operand. In addition, several instructions and apparatus for implementing these instructions are described which obtain performance advantages if the operands are not limited to the width and accessible number of general purpose registers.
Patent CA-2574540-A1 (CA)
Inventor: THOMAS NICHOLAS
IPC: C07K14/47
Filed: 2005-07-22
Abstract: The present invention relates to polypeptide and nucleic acids constructs which are useful for determining the cell cycle status of a mammalian cell. Host cells transfected with these nucleic acid constructs can be used to determine the effects that test agents have upon the mammalian cell cycle.