baber/WOPTO huggingface dataset:
Patent NZ-509375-A (NZ)
Title: Treating ophthalmic infections in mammals with topical application of an oxazolidinone
Inventor: COCHRAN ROBERT
IPC: A61P31/04
Filed: 1999-07-07
Abstract: Described is a method of treating an ophthalmic infection in a useful warm-blooded non-human mammal in need of such treatment. The treatment comprises topical administration of an ophthalmologicallly effective amount of an oxazolidinone such as (S) -N- [ [3- [3-fluoro-4- (4- morpholinyl) phenyl] -2-oxo-5oxazolidinyl] methyl] acetamide. Ophthalmic infections in this invention refer to inflammation of the conjunctiva (conjunctivitis) by staphylococci, streptococci and enterococci, and inflammation of the cornea (keratitis) caused by the same organisms and corneal ulcers. Bacterial conjunctivitis is the most common form of infectious conjunctivitis and bacterial keratitis accounts for 65-90% of all bacterial corneal infections. It is preferred that the ophthalmic infection be bacterial keratitis and bacterial conjunctivitis. The gram-positive microorganisms that cause the ophthalmic infections treated by oxazolidinones include Staphylococci, Streptococci, Enterococci, Bacillus, Corynebacterium, Chlamydia and Neisseria. The important species of these genera are Staphylococcus aureus, Streptococcus viridans, Staphylococcus epidermidis and Streptococcus pneumoniae. The oxazolidinones also treat gram positive and gram-negative infections caused by anaerobes such as Bacteroides fragilis.
Patent NZ-510584-A (NZ)
Title: Methods and compositions for inhibiting neoplastic cell growth
Inventor: ASHKENAZI AVI
IPC: A61P35/00
Filed: 1999-10-05
Abstract: A composition for use in the inhibition of neoplastic cell growth or as an anti-tumour agent, where the composition comprises an effective amount of a PRO172 polypeptide in admixture with a pharmaceutical carrier.
Patent NZ-515966-A (NZ)
Title: Factor VIIa inhibitors
Inventor: KLINGLER OTMAR
IPC: C07D213/71
Filed: 2000-05-27
Abstract: Compound  of  formula (I) are described,  wherein  the substituents are defined herein. The compounds are  used  in the   manufacture  of  medicaments  for  the  treatment   of diseases mediated by the inhibition of factor VIIa.
Patent NZ-518481-A (NZ)
Title: Methane sulphonic salt of morphine for treating pain
Inventor: ILLUM LISBETH
IPC: A61K47/36
Filed: 2000-10-19
Abstract: A composition adapted for nasal delivery comprising the methane salt of morphine with chitosan or a salt derivative thereof is disclosed. The composition may be in a powder, gel, microsphere or gelling solution and can be used for the relief of pain in a non-human animal.
Patent NZ-521492-A (NZ)
Title: A low-moisture pet food product with a firm, chewy texture resulting in an extended chewing time to assist with dental health
Inventor: CUPP CAROLYN JEAN
IPC: A23K1/16
Filed: 2001-03-22
Abstract: There is provided a pet food product comprising an edible protein-rich body having reduced moisture content and a structure providing textural firmness capable of inducing thorough chewing behaviour in a pet to which it is fed. Through such behaviour development of periodontal disorders in the pet animal will be inhibited. The food body preferably has a browned outer surface, achieved by exposure of the body to a source of dry heat. A method of producing the food body includes steps of providing a coherent, edible, protein-rich body, causing moisture content of the body to be in the range from about 20% to 50% by weight and causing the body to have a structure capable of inducing thorough chewing by a pet. The method preferably includes reducing the moisture content of the body after it has been formed.
Patent NZ-526929-A (NZ)
Title: System and method for editing computer-generated documents independently of the creator software application
Inventor: HOOLAHAN RONALD FRANCIS
IPC: G06F17/24
Filed: 2002-01-21
Abstract: A computer system for editing a document to be rendered comprises a memory for storing data and instructions to be performed by a processing unit and a processing unit coupled to the memory. The processing unit is programmed to: generating a first representative computer file comprising instructions in a page description language for describing at least a portion of said document; generating one or more secondary representative computer files wherein at least one of the secondary computer files comprise one or more data fields which correspond to one or more data fields in the first representative computer file and obtaining editing changes made to one or more data fields of at least one of secondary representative computer files in accordance with predetermined rules wherein the editing changes are made independent of one or more computer software application programs used to create the original document.
Patent NZ-536591-A (NZ)
Title: Sulfur-containing proanthocyanidin oligomer composition and production method thereof
Inventor: NONAKA GEN-ICHIRO
IPC: A23L1/30
Filed: 2004-05-25
Abstract: Disclosed is a composition comprising a sulfur-containing proanthocyanidin oligomer as a main component, wherein the oligomer is obtained by concentrating and drying a reaction solution prepared by reacting a plant containing proanthocyanidins or extract thereof with at least one SH group-containing compound selected from a group consisting of cysteine, cystine, glutathione, SH group-containing peptides, and salts thereof. Also disclosed is the above composition for treating and/or preventing hyperlipemia (hyperlipidemia), hypercholesterolemia, hypertension, diabetes, cancers, organ related dysfunctions and/ or brain related dysfunctions.
Patent NZ-536942-A (NZ)
Title: Prodrugs of phosphonate nucleotide analogues and methods for selecting and making same
Inventor: BECKER MARK W
IPC: C07H19/10
Filed: 2001-07-20
Abstract: Disclosed is a method for use of magnesium alkoxide comprising reacting 9-(2-hydroxypropyl)adenine (HPA) or 9-(2-hydroxyethyl)adenine (HEA), magnesium alkoxide, and protected p-toluenesulfonyloxymethylphosphonate to form respectively compounds of the formulae (I) or (II).
Patent NZ-537759-A (NZ)
Title: Combination of chemotherapeutic drugs for increasing antitumor activity
Inventor: BUCALO LOUIS R
IPC: A61K33/243
Filed: 2003-07-11
Abstract: Disclosed herein is a use of: (a) an oxyalkylene containing HDAC inhibitor; and (b) a class of chemotherapeutic agents selected from the group consisting of tubulin interactors, DNA-interactive agents, DNA alkylating agents, and platinum complexes, for preparing a medicament for the treatment of cancer, wherein the medicament is formulated for sequential administration of (a) and (b), whereby administration of (a) for an induction period prior to administration of (b) results in an increase in the anti-tumor activity of (a) and/or (b).
Patent NZ-538070-A (NZ)
Title: Process for preparing the calcium salt of rosuvastatin
Inventor: HORBURY JOHN
IPC: C07D239/42
Filed: 2003-08-07
Abstract: Disclosed is a process for the manufacture of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid calcium salt, comprising addition of a solution of calcium chloride to a solution of a water-soulble salt of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid, at a temperature of 30-45°C, filtering, optionally washing and drying of the resultant product.
Patent NZ-539204-A (NZ)
Title: Degradation of epothilones and ethynyl substituted epothilones
Inventor: HOEFLE GERHARD
IPC: C07C51/353
Filed: 2002-02-27
Abstract: A process for the preparation of 2-methyl-1,3-thiazol-4-yl)-ethynyl substituted epothilones of formula (9) and intermediates thereof is disclosed. Further, a process for a degradation of an epothilone C or an epothilone D, wherein an epothilone C or epothilone D is subjected to an olefin metathesis in the presence of ethylene and subsequently an optional ester hydrolysis is also described. (62) Divided out of 527557
Patent NZ-542375-A (NZ)
Title: Flow regulating valve
Inventor: HIGHAM ANTHONY JOHN
IPC: B05B9/01
Filed: 2004-03-18
Abstract: A flow regulating valve includes a fluid passage for containing a flow of a fluid and a flow rate regulating assembly. The flow regulating assembly includes a sealed pressure chamber, defining a variable volume which is adapted to change in volume in response to a change in a temperature within a sealed pressure chamber. A substance disposed in the sealed pressure chamber so as to be in heat exchange communication with the fluid when the fluid is flowing through the fluid passage. A flow restricting member is disposed in communication with the sealed pressure chamber such that an increase in the variable volume of the sealed pressure chamber results in the flow restricting member moving to selectively increase a flow rate of the fluid through the fluid passage.
Patent NZ-542476-A (NZ)
Title: 2-(Butyl-1-sulfonylamino)-N-[1(R)-(6-methoxy-pyridin-3-yl)-propyl]-benzamide, the use thereof in the form of drug and pharmaceutical preparations containing said compound
Inventor: BRENDEL JOACHIM
IPC: C07D213/64
Filed: 2004-03-05
Abstract: Disclosed is 2-(butyl-1-sulfonylamino)-N-[1(R)-(6-methoxypyridin-3-yl)propyl]benzamide of the formula (I) and its physiologically tolerable salts. The compounds are useful for the treatment or prophylaxis of cardiac arrhythmias, supraventricular arrhythmias, atrial fibrillation and atrial flutters. Also disclosed is 1(R)-(6-methoxypyridin-3-yl)propylamine, a useful intermediate for the preparation of compounds of formula (I).
Patent NZ-544336-A (NZ)
Title: Clamp for attachment to door sill of crashed motor vehicle to provide footing for powered ram
Inventor: DONOVAN KEVIN MICHAEL
Filed: 2005-12-21
Abstract: A clamp 1 for attachment to the crushed lower door sill of a crashed motor vehicle in order to provide a footing for a powered ram for assisting extraction of a trapped occupant is disclosed. The clamp has a pair of pivotally connected opposing jaws 2, 3, each jaw consisting of two spaced apart parallel plates having an arc shaped set of inwardly facing teeth. A threaded rod is arranged so that rotation of the rod by a handle 6 causes the jaws to open or close. One of the jaws includes means 7 for retaining the base of a powered ram. In order to extract the trapped occupant of a crashed motor vehicle the lower sill of the vehicle door is crushed with a suitable separate device. The jaws are then attached to the crashed sill and the rod turned to securely fasten the jaws in place. One end of a powered ram is placed in the ram retaining means 7 while the opposite end is placed against part of the vehicle so that when the ram is extended the part of the vehicle trapping the occupant is pushed away.
Patent NZ-546845-A (NZ)
Title: Flywheel assisted payload launching system
Inventor: DEMOLE FREDERIC JEAN-PIERRE
IPC: F41B15/00
Filed: 2004-10-31
Abstract: A payload launching system comprising a cable, an end portion of which is adapted for releasably coupling with a rocket 16, a rotary member 11 adapted for rotation on an axis and drive means for disengageably engaging with the rotary member 11 so as to rotate the rotary member 11 on the axis, and the rotary member 11 is provided with a surface for receiving a portion of the cable 14 remote from a rocket 16, and the surface has a curved profile, the radial dimension of which increases progressively from the axis in an arcuate direction of the axis, and means for engaging a portion of the cable 14 remote from a rocket 16 with the rotary member 11, while the rotary member 11 is rotating, so that the portion of the cable 14 remote from a rocket 16 locates on the surface, while an end portion of the cable 14 remote from a rocket 16 is restrained at a location on the rotary member 11 adjacent to a centre of the rotary member 11, characterised in that there is provided a rocket 16 and there is provided transferring means, between the cable 14 and a rocket 16, the transferring means being adapted to transfer the pulling force of the cable 14 to the rocket 16, and the pulling force of the cable 14 is applied to the rocket 16 at multiple points, and the transferring means transfer the pulling force to the rocket 16 at points located on the rocket 16 away from that particular point that is located on the rocket 16 the most at the front of the front part 15 of the rocket 16, and the transferring means transfers the pulling force to the rocket 16 at a point located on the rocket 16 away from the base of the rocket 16.
Patent NZ-562816-A (NZ)
Title: Multilumen catheters and methods for their use
Inventor: CONSTANTZ BRENT R
IPC: A61F2/958
Filed: 2003-03-18
Abstract: A multilumen catheter is provided. The catheter (10) include a proximal end (14) and a distal end (12) separated by a non-coaxial multilumen tube, and includes a three port manifold (18) at its proximal ends, comprises at least two offset ports (11a, 11c) with luer valves and a central port (11b) comprising a Touhy-Borst valve. The proximal and distal ends are separated by a non-coaxial two lumen tube. Also provided are systems for use in flushing a vascular site with fluid, usually at least two different fluids, where the subject systems are made up of two multilumen catheters according to the subject invention, where one of the catheters is inserted inside of the other. In addition, kits comprising various components of the subject systems, e.g., at least two different multilumen catheters, are provided. The subject multilumen catheters, systems and kits find use in a variety of different applications in which it is desired to flush a vascular site with at least one and preferably two different fluids, where particular applications of interest include the treatment of vascular lesions.
Patent NZ-565590-A (NZ)
Title: Use of a protein free composition comprising cholinic acid and a phosphosphlipid for the treatment or prevention of conditions caused by gram-positive bacteria
Inventor: LEVINE DANIEL
IPC: A61K31/661
Filed: 2006-08-25
Abstract: Disclosed is a use of a protein free, peptide free, composition comprising cholanoic acid or cholanoic acid salt and a phospholipid in the manufacture of a medicament for treating or preventing a condition caused by Gram-positive bacteria, selected from the group consisting of: sepsis, septic shock, systemic inflammatory response syndrome (SIRS), SIRS with organ dysfunction or failure, organ failure, and organ dysfunction, in a subject in need thereof, wherein the medicament is formulated for intravenous administration. Additionally the composition may further comprise a neutral lipid.
Patent NZ-567339-A (NZ)
Title: Cable connector device for a battery
Inventor: DOWMAN KEVIN PATRICK
IPC: H01R4/38
Filed: 2006-10-20
Abstract: A cable connector device for use on a battery terminal post. The cable connector includes a conductive mounting cap having an internal mounting wall with a surface area corresponding with the surface area of a said battery mounting post to enable, in use, the cap to be mountable over the said battery mounting post. The mounting cap includes a cable mounting post integral with or attachable to the mounting cap, the cable mounting post being adapted with a cable fastening means, in use, to receive and fasten an electrical cable thereto. The inner wall of the mounting cap is provided with a female thread that is configured and arranged, in use, to cut an opposing thread on at least a portion of the terminal post and firmly attach the mounting cap to the terminal post, the post being sufficiently malleable to allow the opposing thread to be formed.
Patent NZ-585650-A (NZ)
Title: Shredder assembly adapted to perform both cutting and sizing at the same site
Inventor: GROSS THOMAS R
IPC: B02C18/14
Filed: 2008-11-10
Abstract: Disclosed is a self-contained shredder assembly for reducing and sizing material without the need for an auger or a conveyor to move material between cut and sizing operations. The shredder assembly comprises a support; a tapered cutting drum that is impervious to reduced material passing to the interior of the cutting drum, the tapered cutting drum rotatably mounted about the support and having at least one cutting implement; the cutting drum including at least one channel or pocket adjacent to the cutting implement to receive reduced material therefrom, the at least one channel or pocket being open at the surface of the drum and having a basin that is impervious to reduced material passing to the interior of the cutting drum; a drive connected to the tapered cutting drum; a sizing chamber disposed adjacent to the tapered cutting drum and in material flow communication with the at least one channel or pocket; at least one impeller joined with the tapered cutting drum; at least one sizing screen disposed down stream from and adjacent to the at least one impeller, the at least one impeller and the at least one sizing screen each residing at least partially within the sizing chamber. Also disclosed is a shredder having a support; a reducing chamber, a tapered cutting drum rotatably mounted about the support and disposed in the reducing chamber, the tapered cutting drum having at least one channel for receiving reduced material, the at least one channel having a basin; at least one cutting implement disposed about an outer surface of the cutting drum for reducing material; and a sizing chamber in communication with and disposed to the side of the cutting drum, the sizing chamber including: at least one impeller connected to the tapered cutting drum, a screen downstream from the impeller, the at least one impeller positioned to force reduced material through the screen during operation, wherein the basin of the channel is impervious to reduced material to prevent such material from passing to the drum interior and to maintain momentum of moving the material until the material enters the sizing chamber.
Patent NZ-588876-A (NZ)
Title: A clamp apparatus to prevent fluid flow in tubes with a detent holding the clamp in either an open or a closed position
Inventor: CLARKE CHRISTOPHER J
IPC: F16K7/06
Filed: 2005-06-24
Abstract: A clamp apparatus is for selectively occluding a resilient tube to prevent free flow of fluid in the tube. The device comprises a base member to which the resilient IV tube is attached or through which it passes, and a slide clamp that slides relative to the base member and relative to the tube. The aperture in the slide clamp has a relatively open hole at one end, through which the tube passes when the slide clamp is an open position, allowing fluid to flow through the tube. The aperture also has a relatively constricted slot at the other end, through which the tube passes when the slide clamp is in the occluding position, preventing fluid flow through the tube. A deflectable cantilevered locking arm on the base interlocks with a detent on a top surface of the slide clamp to lock the slide clamp at the occluding position to avoid inadvertent free flow. A release tab that is used to release the locking arm from the slide clamp is located off centre to avoid inadvertent activation. The slide clamp has a pushing flange capable of receiving a digit of an operator.
Patent NZ-591504-A (NZ)
Title: 3,5-bis(3,4dihydroxyphenyl)pyrazole, compositions and methods for the treatment of beta-amyloid diseases and synucleinopathies
Inventor: ESPOSITO LUKE A
IPC: C07C37/16
Filed: 2009-06-26
Abstract: Disclosed herein is 3,5-bis(3,4 dihydroxyphenyl) 1,2,4 triazole or pharmaceutically acceptable salts thereof, processes for their preparation, compositions comprising said compound and uses thereof. Said compounds are useful for inhibiting the formation, deposition, accumulation or persistence of beta amyloid or alpha-synuclein aggregates and therefore are useful in the treatment of Alzheimer's disease, Down's syndrome, hereditary cerebral haemorrhage with amyloidosis of the Dutch type and cerebral beta-amyloid angiopathy.
Patent NZ-599389-A (NZ)
Title: Mobile television antenna with integral signal meter display
Inventor: KING LAEL
IPC: H01Q1/32
Filed: 2012-01-14
Abstract: Disclosed is an over-the-air (terrestrial) television antenna system (100). The system (100) includes an antenna (102) configured to receive television signals in the VHF and UHF frequency bands from terrestrial transmitters; an adjustment device (108) comprising an adjustment knob (not shown); and a display (not shown). The display is located adjacent to the adjustment knob and configured to indicate the relative strength of the television signals received by the antenna (102). A shaft (110) mechanically coupling the adjustment device (108) to the antenna (102) may be provided such that rotation of the knob rotates the antenna (102). The antenna system (100) may further include a base (106) and a riser (104) disposed on the base (106); with the antenna (102) disposed on the riser (104). The antenna system (100) may be mounted on the roof of a vehicle.
Patent NZ-601713-A (NZ)
Title: Solid pharmaceutical composition for buccal administration of agomelatine
Inventor: PEAN JEAN-MANUEL
IPC: A61K9/20
Filed: 2012-08-08
Abstract: ABSTRACT - 601713 The disclosure relates to a solid buccal pharmaceutical composition intended for systemic action, which is a tablet to be sucked, a pastille to be sucked, a lozenge to be sucked, or a solid obtained by hot-melt extrusion or injection-moulding, comprising agomelatine or one of its hydrates, complexes, co-crystals, crystalline forms, addition salts with a pharmaceutically acceptable acid or base, and one or more excipients selected from diluents, binders, flow agents, lubricants, coating agents, plasticisers, flavourings, counter-irritants and sweeteners, characterised in that it makes it possible to obtain a release time of the active ingredient comprised between 3 and 30 minutes and an absolute bioavailability greater than 25%. These compositions have a slow erosion release of agomelatine and are suitable for the treatment of major depression, seasonal affective disorder, generalized anxiety disorder, obsessional compulsive disorder, bipolar disorders, sleep disorders, cardiovascular pathologies, pathologies of the digestive system, insomnia and fatigue due to jet-lag, appetite disorders and obesity, and any pathology associated with deregulation of circadian rhythms.
Patent NZ-618126-A (NZ)
Title: Thermo-mechanical processing of nickel-base alloys
Inventor: FORBES JONES ROBIN M
IPC: C22F1/10
Filed: 2012-05-07
Abstract: Disclosed is a thermo-mechanical treatment process for nickel-base alloys. The process comprising a first heating step comprising heating a nickel-base alloy workpiece to a temperature in the range of 1093°C (2000°F) to 1163°C (2125°F); a first forging step comprising rotary forging the heated nickel-base alloy workpiece to a reduction in area of 30% to 70%, wherein the nickel-base alloy workpiece is at a temperature in the range of 1093°C (2000°F) to 1163°C (2125°F) when the first forging step begins; a second heating step comprising heating the rotary-forged nickel-base alloy workpiece to a temperature in the range of 954°C (1750°F) to 1052°C (1925°F), wherein the rotary-forged nickel-base alloy workpiece is maintained at a temperature of at least 926°C (1700°F) between completion of the first forging step and beginning of the second heating step; and a second forging step comprising rotary forging the heated nickel-base alloy workpiece to a reduction in area of 20% to 70%, wherein the nickel-base alloy workpiece is at a temperature in the range of 954°C (1750°F) to 1052°C (1925°F) when the second forging step begins; wherein the nickel-base alloy workpiece comprises, by weight, up to 0.05% carbon, 27.0% to 31.0% chromium, up to 0.5% copper, 7.0% to 11.0% iron, up to 0.5% manganese, up to 0.015% sulfur, up to 0.5% silicon, at least 58% nickel, and incidental impurities. Also disclosed is a similar method wherein the temperatures of the process are defined in relation to the M23C6 carbide solvus temperature of the nickel-base alloy having by weight, up to 0.05% carbon, 27.0% to 31.0% chromium, up to 0.5% copper, 7.0% to 11.0% iron, up to 0.5% manganese, up to 0.015% sulfur, up to 0.5% silicon, at least 58% nickel, and incidental impurities.