baber/WOPTO huggingface dataset:
Patent AU-2012212264-A1 (AU)
Title: Nucleic acid molecules encoding novel herpes antigens, vaccine comprising the same, and methods of use thereof
Inventor: WEINER DAVID B
IPC: A61K48/00
Filed: 2012-01-31
Abstract: Provided herein are nucleic acid sequences that encode novel consensus amino acid sequences of herpes virus antigens, as well as genetic constructs/vectors and vaccines expressing the sequences. Also provided herein are methods for generating an immune response against herpes virus using the vaccines that are provided.
Patent AU-2012214259-A1 (AU)
Title: Surrogates of post-translationally modified proteins and uses thereof
Inventor: CHOREV MICHAEL
IPC: G01N33/574
Filed: 2012-02-10
Abstract: The present invention provides compounds that are surrogates of post-translationally modified proteins and uses thereof. Numerous diseases are associated with post- translationally modified proteins that are difficult to obtain in homogenous form and in quantities needed for immunization and use as convenient standards, calibrators, and/or reference compounds that facilitate the detection and analysis of endogenous post- translationally modified proteins. The surrogate compounds of the invention typically comprise antigenic epitopes (one of which carries a post-translational modification) that are tethered by a flexible and hydrophilic linker. The resulting compound behaves like a surrogate of the post-translationally modified protein because it preserves the character of the included antigens and allows recognition by specific antibodies targeting the individual antigens. The surrogate compounds may be prepared by covalently joining two or more polypeptide epitopes using one or more linkers, wherein at least one of the epitopes comprises a post-translational modification. In one aspect, the surrogate compounds of the invention comprise a C-terminal epitope and a glycated epitope of human CD59. The inventive methods allow quantification of the levels of glycated CD59 in the serum in human subjects, particularly those with diabetes or pre-diabetes. This technological platform of post-translationally modified protein surrogates can be applied to other diseases associated with post-translationally modified proteins (e.g., autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and systemic lupus erythematosus). In another aspect, the invention provides antibodies that bind specifically to the compounds of the invention and methods for producing such antibodies.
Patent AU-2012261534-A1 (AU)
Title: Portable electronic device with interface reconfiguration mode
Inventor: ANZURES FREDDY A
IPC: G06F3/048
Filed: 2012-11-30
Abstract: Abstract A portable electronic device and a method for a portable electronic device. A first plurality of application icons are displayed in a first region on the touch-sensitive display. A tapping gesture on a respective application icon at a first location on the touch-sensitive display activates a corresponding application. A first predefined user action comprising a finger contact on the respective application icon at the first location held for more than a predefined time period initiates a predefined user interface reconfiguration mode that allows a user to reposition one or more displayed application icons.
Patent AU-2012262883-A1 (AU)
Title: Optical coherence tomography and pressure based systems and methods
Inventor: PETROFF CHRISTOPHER
IPC: A61B5/0215
Filed: 2012-05-14
Abstract: In part, the invention relates to methods, apparatus, and systems suitable for determining a fractional flow reserve (FFR) and variations of modifications thereof One embodiment relates to a method and apparatus for obtaining a corrected FFR in a vessel having a stenosis. In one aspect, the invention relates to an apparatus for measuring corrected FFR of a vessel having a stenosis. In one embodiment, the apparatus includes a probe comprising an optical coherence tomography assembly and a pressure assembly; and a processor in communication with the optical coherence tomography assembly and the pressure assembly. In one embodiment, the pressure assembly measures values of pressure in predetermined locations the vessel and communicates them to the processor. In one embodiment, a dual guidewire is used to reduce the interference in the pressure measurement.
Patent AU-2012265293-A1 (AU)
Title: Scaffolding component having at least one connection head and method for fastening a scaffolding component having at least one connection head to a vertical scaffolding element
Inventor: KRELLER HELMUT
IPC: E04G7/32
Filed: 2012-05-31
Abstract: The invention relates to a scaffolding component (45) with at least one connection head (61) for forming a releaseable connection with a vertical scaffolding element (41) extending in the direction of a longitudinal axis (47). On this scaffolding element is fastened a projection (44) which extends transversely to the longitudinal axis (47) thereof and which has an aperture (55) for plugging through a wedge (62). The connection head has an upper head part (74) with an upper wedge opening (80) and a lower head part (75) with a lower wedge opening (81), for the wedge (62) which can be plugged through the wedge openings (80, 81). Between the upper head part (74) and the lower head part (75) is arranged a slot (67) which is open towards the front and which is intended for plugging the connection head (61) onto the projection (44). The slot is bounded upwardly and downwardly by slot surfaces which extend on both sides of a horizontal centre plane. The connection head (61) has a wedge support body (85) with wedge support surfaces which is arranged above the slot (67) so as to engage over the slot (67) towards the front, for vertically supporting the wedge (62) in the region of its lower wedge end against an unintended movement of the wedge (62) vertically downwardly into a blocking position in which the connection head (61) would be blocked from being plugged onto the projection (44) by way of its slot (67) in a substantially horizontal plugging-on direction (105). The wedge, when it is supported on the wedge support surfaces of the wedge support body (85) and protrudes upwardly with a wedge part (190) from the upper head part (74), can be pivoted relative to the connection head (61) into a pivoting stop position in a vertical plane extending perpendicularly to the horizontal centre plane of the slot (67), in which position the wedge (62) projects forwardly in front of the upper head part (74) of the connection head (61). The connection head (61) has, above the wedge support surfaces of the wedge support body (85), a wedge pivoting abutment (86) against which the wedge (62), when it is supported on the wedge support surfaces of the wedge support body (85), can be made to bear or bears in the region of its lower wedge end and about which the wedge (67), when it bears against the wedge pivoting abutment (86), can be pivoted rearwardly by its wedge part (190) and at the same time forwardly by its lower wedge end in order to release the wedge (62), with the result that the wedge (62) can pass, under the force of gravity and/or with spring force assistance, automatically vertically downward while crossing the slot (67) into or through the lower wedge opening (81). The invention also relates to a method for fastening such a scaffolding component (45) to a vertical scaffolding element (41).
Patent AU-2012275355-A1 (AU)
Title: Compositions and methods for inhibiting gene expression of Hepatitis B virus
Inventor: CHIN DANIEL
IPC: C12N15/113
Filed: 2012-06-28
Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a Hepatitis B Virus gene. The invention also relates to a pharmaceutical composition comprising the dsRNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by Hepatitis B Virus infection using said pharmaceutical composition: and methods for inhibiting the expression of a Hepatitis B Virus gene in a cell.
Patent AU-2012275562-A1 (AU)
Title: Compositions, uses, and preparation of platelet lysates
Inventor: COPLAND IAN B
IPC: A61K35/19
Filed: 2012-06-26
Abstract: In certain embodiments, this disclosure describes compositions comprising platelet lysates depleted of fibrinogen. In a further embodiment, the composition further comprises a cell culture medium component. This disclosure also provides a method for preparing the composition, comprising the steps of (a) lysing platelets providing a lysate; (b) removing cell debris; and (c) depleting fibrinogen by forming a removable mass by adding a metal salt such as calcium chloride. Furthermore, the disclosure also describes the product produced using said method.
Patent AU-2012284205-A1 (AU)
Title: Methods of increasing yield and stress tolerance in a plant
Inventor: BASU SHIB
IPC: C12N9/16
Filed: 2012-07-16
Abstract: The present invention relates generally to the field of molecular biology and regards various polynucleotides, polypeptides and methods that may be employed to enhance yield in transgenic plants. Specifically the transgenic plants may exhibit any one of the traits consisting of increased yield, increased tolerance to abiotic stress, increased cell growth and increased nutrient use efficiency.
Patent AU-2012290734-A1 (AU)
Title: 3-hydroxyanthranilic acid (3-HAA) therapy for prevention and treatment of hyperlipidemia and its cardiovascular complications
Inventor: HANSSON GORAN K
IPC: A61P3/06
Filed: 2012-07-13
Abstract: The present invention relates to the use of a tryptophan metabolite, 3- hydroxyanthranilic acid (3-HAA)or a functional analogue thereof, for prophylactic and/or therapeutic treatment of mammals, in special humans, against hyperlipidemia and its cardiovascular complications, i.e atheroma formation, myocardial infarction and heart failure, ischemic stroke and transient ischemic attacks, renal impairment, aortic aneurysms and critical limb ischemia caused by atherosclerosis.
Patent AU-2012299720-A1 (AU)
Title: Knit with barbs on both faces
Inventor: MENEGHIN ALFREDO
IPC: D04B21/12
Filed: 2012-08-03
Abstract: The present invention relates to a knit with outwardly protruding barbs on each of its faces, said knit being obtained by: i) knitting yarns on at least four guide bars, one bar forming a chain leaving one needle free in two; two bars threaded with monofilament yarn generating loops protruding outwards from the faces of said knit; the fourth bar producing the connection between the yarns of the three other bars, ii) thermosetting the knit obtained at i), iii) forming the barbs by melting the loops. The invention also relates to a prosthesis comprising such a knit.
Patent AU-2012300221-A1 (AU)
Title: Isolating and therapeutic use of perivascular medicinal cells
Inventor: CAPLAN ARNOLD I
IPC: A61K35/12
Filed: 2012-08-27
Abstract: Disclosed are perivascular medicinal cells (PVMCs), methods of isolating PVMCs, and a composition comprising PVMCs having medicinal capabilities. Specifically, the disclosure provides a method of isolating PVMCs from an umbilical cord blood vessel or from bone. The disclosure further provides a method of making an enhanced, autologous bone graft, a method of stimulating bone regeneration comprising administering a therapeutically effective amount of bone-derived PVMCs, a method of reconstructing bone tissue, and methods of treating a disease that affects cellular function. PVMCs capable of secreting a site-dependent trophic factor are also described.
Patent AU-2012321759-A1 (AU)
Title: Vegetation bed, and method for cultivating plants
Inventor: KAJIYAMA HIROSHI
IPC: A01G1/00
Filed: 2012-10-11
Abstract: The present invention provides a vegetation bed comprising knit multifilament fibers made from aliphatic polyester, the vegetation bed having excellent transportability and excellent properties with respect to ultraviolet degradation. The present invention pertains to a vegetation bed composed of cylinders of knit fabric composed of a multifilament fiber comprising aliphatic polyester, and filled with a culture, the fabric being placed contiguously side by side, or to a vegetation bed characterized in being composed of two cylinders of knit fabric that are placed contiguously side by side, having a concave portion occurring at their top in which a culture is placed.
Patent AU-2012328561-A1 (AU)
Title: Benzoxazolinone compounds with selective activity in voltage-gated sodium channels
Inventor: LAYTON MARK E
IPC: C07D263/54
Filed: 2012-10-26
Abstract: Disclosed are compounds of Formula (A) or a salt thereof, wherein "Het", R
Patent AU-2012329301-A1 (AU)
Title: Molded article extractor and method
Inventor: GRIDLEY JASON
IPC: B29C35/02
Filed: 2012-09-21
Abstract: A tire tread extractor used in the manufacture of treads includes a frame, a first nip roller rotatably associated with the frame, and a second nip roller rotatably associated with the frame. The first and second nip rollers are adapted to engage a tire tread at least partially resident in a mold. A driving mechanism associated with the first and/or second nip rollers operates to impart rotational motion thereto. The frame is configured for longitudinal movement along a substantial portion of a longitudinal length of the mold while maintaining the first and second nip rollers in a spaced relation to the mold.
Patent AU-2012332131-A1 (AU)
Title: Wireless energy transfer modeling tool
Inventor: VERGHESE SIMON
IPC: H02J17/00
Filed: 2012-11-05
Abstract: A method includes defining and storing one or more attributes of a source resonator and a device resonator forming a system, defining and storing the interaction between the source resonator and the device resonator, modeling the electromagnetic performance of the system to derive one or more modeled values and utilizing the derived one or more modeled values to design an impedance matching network.
Patent AU-2012333459-A1 (AU)
Title: Arthropod pest control composition
Inventor: NATSUHARA KATSUYA
IPC: A01N43/76
Filed: 2012-11-02
Abstract: Disclosed is an arthropod pest control composition comprising 2-(2,6-difluorophenyl) -4-[4- (1,1-dimethylethyl) -2-ethoxyphenyl] -4,5-dihydrooxazole and an inert carrier, wherein the volume median diameter of 2- (2,6-difluorophenyl) -4- [4- (1,1-dimethylethyl) -2-ethoxyphenyl] -4,5-dihydrooxazole is from 1.5 to 5.9 μm.
Patent AU-2013201229-A1 (AU)
Title: A sprung walking beam suspension
Inventor: MCFARLANE SCOTT
IPC: B60G5/00
Filed: 2013-03-04
Abstract: -9 A pedestal assembly for use in a suspension assembly for suspending a tandem wheel axle assembly from a vehicle chassis. The pedestal assembly includes a longitudinally 5 extending body including a lower portion with means of connection to a walking beam connecting two longitudinally spaced wheel axles of said tandem axle assembly, and a forwardly projecting portion and a rearwardly extending portion. It further includes a hanger configured to be rigidly connected to an underside of said chassis, the hanger including a front portion with a means of hingedly suspending the forwardly projecting 0 portion of the pedestal body, and a rear portion which is springedly associated with the rearwardly extending portion of the pedestal body
Patent AU-2013201459-A1 (AU)
Title: Method and apparatus for production of a flexible duct
Inventor: WILSON STEPHEN ROBERT
IPC: B29C53/58
Filed: 2013-03-13
Abstract: Abstract A method of and apparatus for forming a flexible duct including helically winding a tube containing insulating material, wherein the tube is delivered into its initial winding at a rate of delivery so that at the outer periphery of the winding the tube remains 5 substantially unstretched and uncompressed circumferentially while at the inner periphery the tube is allowed to pucker circunferentially. Also a method of forming a flexible duct, including the steps of drawing a strip of flexible material relatively laterally of and into a forming head that delivers the strip forwardly from the forming head as a tubular casing in the direction of the axis of the casing, and delivering fibrous insulating 0 material into said casing at the forming head as a gas-entrained stream of the material, wherein the tube is delivered into its initial winding at a rate so that at the outer periphery of the winding the tube remains substantially unstretched and uncompressed circurnferentialy, while at the inner periphery the tube is allowed to pucker circumferentialy.
Patent AU-2013205530-A1 (AU)
Title: Compositions and methods for the treatment of infections and tumors
Inventor: FREEMAN GORDON
IPC: A61K39/395
Filed: 2013-04-12
Abstract: PD-I antagonists are disclosed that can be used to reduce the expression or activity of PD-I in a subject. An immune response specific to an infectious agent or to tumor cells can be enhanced using these PD- 1 antagonists in conjunction with an antigen from the infectious agent or tumor. Thus, subjects with infections, such as persistent infections can be treated using PD-I antagonists. In addition, subjects with tumors can be treated using the PD-I antagonists. In several examples, subjects can be treated by transplanting a therapeutically effective amount of activated T cells that recognize an antigen of interest and by administering a therapeutically effective amount of a PD-I antagonist.
Patent AU-2013215251-A1 (AU)
Title: Combination of a RTK inhibitor with an anti - estrogen and use thereof for the treatment of cancer
Inventor: YOVINE ALEJANDRO
IPC: A61K31/496
Filed: 2013-01-30
Abstract: A pharmaceutical combination comprising (a) a RTK inhibitor selected from the group consisting of compounds of Formula I or a tautomer thereof, compounds of Formula II or a tautomer thereof, compounds of Formula III or a tautomer thereof, a pharmaceutically acceptable salt of the compound, a pharmaceutically acceptable salt of the tautomer, or a mixture thereof; and (b) one or more anti-estrogen compounds, or a pharmaceutically acceptable salt thereof; such as tamoxifen, toremifene, fulvestrant, raloxifene or raloxifene hydrochloride; the uses of such combination in the treatment or prevention of proliferative diseases; and methods of treating a subject suffering from a proliferative disease; and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.
Patent AU-2013237718-A1 (AU)
Title: Method, apparatus and system for selecting a frame
Inventor: LEUNG KA MING
IPC: G06T17/05
Filed: 2013-10-04
Abstract: -33 Abstract METHOD, APPARATUS AND SYSTEM FOR SELECTING A FRAME A method of selecting a frame from a plurality of video frames captured by a camera 5 (120). The method determines features to which map points in a three dimensional space are projected. A histogram of the determined features for a plurality of regions in the frame is created. One of the regions may be determined as being an unmapped region based on the created histogram. The frame is selected based on the size of the unmapped region. "7QQA-}QAu,1 fDfnQ:flrf Cnci Ae Cilnel1
Patent AU-2013250020-A1 (AU)
Title: Oil recovery from oil sludge with nanoemulsion surfactant
Inventor: SEE CHUN HWA
IPC: C09K8/58
Filed: 2013-04-22
Abstract: A method of treating a first batch of oil sludge containing entrapped oil residue comprises the steps comprises the steps of bringing into contact the first batch of oil sludge to a liquid composition of an emulsion with or without a carrier, wherein the emulsion comprises an alkylpolyglucoside surfactant in 2 to 40% by weight of total composition; a co-surfactant in 1 to 30% by weight of total composition selected from the group consisting of C3 to C18 alcohols, C3 to C18 alkyl lactates, lecithins, C3 to C18 fatty acids and any mixtures thereof; an oil phase in 15 to 90% by weight of total composition; and an aqueous phase in 0.5 to 20% by weight of total composition; homogenizing the liquid composition with the first batch of oil sludge; and fluidizing the oil sludge that the oil residues are substantially dissociated from the solid object forming a liquid phase including the liquid composition and the separated oil.
Patent AU-2013251054-A1 (AU)
Title: Method for manufacturing a cementitious composition
Inventor: ONG FRANK SHAODE
IPC: C04B38/08
Filed: 2013-04-19
Abstract: A method of expanding expandable polymeric microspheres including contacting an aqueous slurry including unexpanded, expandable polymeric microspheres with steam in-situ during manufacture of acementitious composition or article, wherein the aqueous slurry optionally further includes an admixture therefor. A method of manufacturing a cementitious composition or article includes: (i) contacting an aqueous slurry of unexpanded, expandable polymeric microspheres with steam proximate to and/or during said manufacturing of the cementitious composition to create expanded polymeric microspheres; (ii) pre-wetting the expanded polymeric microspheres; and (iii) mixing the pre-wetted, expanded polymeric microspheres with cement and water to form the cementitious composition, wherein the aqueous slurry optionally further comprises an admixture therefor.
Patent AU-2013251207-A1 (AU)
Title: Subsea umbilical
Inventor: KARLSEN STIAN
IPC: H01B9/00
Filed: 2013-10-30
Abstract: Abstract The present invention provides an umbilical 1 for subsea application comprising at least one power phase 9, each power phase comprises at least one conductor 2, wherein the at least one conductor is a massive conductor made in aluminium, or any suitable alloy thereof, and wherein the at least one conductor has sufficient tensile strength to ensure that the umbilical supports operating loads without requiring any additional load bearing elements. Fig. 3 Fig. 4
Patent AU-2013277130-A1 (AU)
Title: Accessory drive decoupler
Inventor: MCCRARY PAUL T
IPC: F16D41/20
Filed: 2013-06-20
Abstract: Assemblies for selectively coupling torque between rotating components and belt drive systems including the same are disclosed. The assembly includes a rotatable input member and a rotatable output member operatively connected to one another by a one-way clutch for rotation together in a predominant direction. A spring is included in the assembly with a first end thereof engaged to the one-way clutch and a second end thereof engaged to the rotatable input member. The spring has no preload in an unengaged position of the one-way clutch and rotates with the rotatable input member during a positive torque condition to rotate a component of the one-way clutch to activate the one-way clutch into an engaged position. Then, when the one-way clutch is in the engaged position, the spring radially expands and thereby provides isolation between the rotatable input member and the rotatable output member.
Patent AU-2013295647-A1 (AU)
Title: Multimeric fusion protein vaccine and immunotherapeutic
Inventor: MOND JAMES J
IPC: A61K39/21
Filed: 2013-07-26
Abstract: The present disclosure provides fusion proteins that incorporate unique mechanisms for multimerizmg antigens to enhance their immunogenicity. The fusion proteins comprise at least two antigens, or other vaccine related proteins, separated by a linker sequence and an oligomerization domain. When expressed, the fusion protein forms a muKimeric protein complex, This approach can be used to muHimeri?.e a single antigen/protein or to create multimers comprising two or more different antigens/proteins. Also provided are nucleic acids encoding the fusion proteins, Yet another aspect is directed to methods of inducing or suppressing an immune response in a subject by administering to the subject a vaccine composition comprising a fusion protein or nucleic acid encoding the fusion protein, optionally without using an adjuvant.
Patent AU-2013330222-A1 (AU)
Title: Novel flavonoid compounds and uses thereof
Inventor: MCLACHLAN GRANT ANDREW
IPC: A61P9/00
Filed: 2013-10-11
Abstract: The present disclosure provides a compound of the following formula, racemates, enantiomers, prodrugs and salts thereof: Formula (I). Also provided is the use of these compounds for the treatment of ischemia and reperfusion injuries. Further applications include the treatment of diseases caused by cell apoptosis and / or cell necrosis.