baber/WOPTO huggingface dataset:
Patent CA-2865506-C (CA)
Title: Composition and method for diversification of target sequences
Inventor: CUMMINGS W JASON
IPC: C12N15/79
Filed: 2013-03-13
Granted: 2021-07-06
Abstract: The disclosure relates generally to the targeting of genes to, and their integration into, an innnnunoglobulin (antibody) heavy chain locus. In particular, the methods described herein contemplate replacing the single rearranged heavy chain V, D, and J genes of a B cell lymphoma such as DT40 with independently rearranged VH-D-JH genes of chicken, in a system for generating immunoglobulin diversity. Also contemplated is replacement of the chicken VH-D-JH with rearranged VH-D-JH genes of other vertebrates including human in a system for generating immunoglobulin diversity, with the exception of any substitution disclosed and claimed in PCT application WO 2009/029315 A2. Regions upstream of the rearranged VH gene, and downstream of the rearranged JH genes, are identified and incorporated into the immunoglobulin heavy chain gene-targeting vectors for efficient gene replacement. Also described is construction of a diverse chicken immunoglobulin heavy chain VDJ library in DT40 by homologous gene replacement of the single endogenous rearranged VDJ gene with a chicken VDJ repertoire using the described targeting vectors. The methods are useful for generating a diverse library of immunoglobulins that can be screened for binding to desired target antigens. Compositions include the unique targeting vectors, the diverse chicken heavy chain VDJ library in the targeting vectors, and the diverse chicken VDJ DT40 library that is created by homologous gene replacement of the single endogenous rearranged VDJ gene with a chicken VDJ repertoire, using the targeting vectors.
Patent CA-2872013-C (CA)
Inventor: REMMER MICHAEL
IPC: A22C21/02
Filed: 2012-03-28
Granted: 2016-10-11
Abstract: L'invention concerne un procédé de fonctionnement d'un appareil de plumaison de volaille, un mécanisme d'entraînement étant utilisé pour faire tourner une pluralité de têtes de ramassage d'un banc de ramassage, et un tel banc de ramassage. Chaque tête de ramassage est montée sur un côté extérieur d'un élément couvercle sur un axe faisant saillie à travers une ouverture dans l'élément couvercle et supportée par un palier. Le mécanisme d'entraînement est agencé sur un côté intérieur de l'élément couvercle à l'opposé des têtes de ramassage. Afin de protéger le mécanisme d'entraînement d'une détérioration, un gaz ou de l'air est amené à s'écouler le long d'un trajet d'entrée sur le côté intérieur de l'élément couvercle et vers le mécanisme d'entraînement. Le gaz ou l'air a une humidité relative inférieure à l'air entourant les têtes de ramassage, lorsque l'appareil est en fonctionnement, ce qui aère ainsi toute humidité entrant dans le banc de ramassage. Afin de réduire davantage l'entrée d'eau, il est préférable que l'écoulement de gaz ou d'air amène une surpression sur le côté intérieur de l'élément couvercle, qui est, de préférence à tout moment, supérieure à la pression sur le côté extérieur.
Patent CA-2873616-C (CA)
Inventor: CHOWDHURY DEWAN FAZLUL HOQUE
IPC: A61B5/145
Filed: 2013-05-21
Granted: 2020-06-30
Abstract: A method of monitoring the level of an analyte such as glucose in a subject comprises repeated steps of extracting a quantity of the analyte from the subject into a sample, for example using reverse iontophoresis, then measuring the concentration of the analyte with a method that depletes the analyte. Whereas known methods aim to deplete the analyte fully between extraction steps, the present method allows the concentration to build up with each cycle and measures successive changes in concentration. The higher concentrations present permit more reliable measurements to be made. The sample may be primed with an initial quantity of the analyte.
Patent CA-2876789-C (CA)
Inventor: CRAVO DANIEL
IPC: A61K31/4365
Filed: 2013-06-28
Granted: 2017-01-31
Abstract: Activators of AMPK and therapeutic uses thereof The invention relates to compounds that are direct activators of AMPK (AMP-activated protein kinase) and their use in the treatment of disorders regulated by activation of AMPK. For instance, compounds according to the invention are useful for the treatment of diabetes, metabolic syndrome, obesity, liver disease, hepatic steatosis, non alcoholic fatty liver disease (NAFLD), non alcoholic steato- hepatitis (NASH), liver fibrosis, dyslipidemia, hypertriglyceridemia, hypercholesterolemia, inflammation, cancer, cardiovascular diseases, atherosclerosis, high blood pressure, retinopathies or neuropathies.
Patent CA-2880203-C (CA)
Inventor: VIJAY MOHAN M
IPC: B24C5/00
Filed: 2009-07-16
Granted: 2017-02-21
Abstract: A method of prepping a surface using a high-frequency forced pulsed waterjet entails generating a high-frequency signal having a frequency f using a high-frequency signal generator, applying the high-frequency signal to a transducer having a microtip to cause the microtip of the transducer to vibrate to thereby generate a forced pulsed waterjet through an exit orifice of a nozzle having an exit orifice diameter d and a length L. The forced pulsed waterjet prepares the surface to within a predetermined range of surface roughness. The surface roughness is determined by selecting operating parameters comprising a standoff distance (SD), a traverse velocity V TR of the nozzle, a water pressure P, a water flow rate Q, a length-to-diameter (L/d) ratio, a microtip-to-orifice distance (a), the frequency f, and an amplitude A of the high-frequency signal.
Patent CA-2881233-C (CA)
Inventor: GAO JINSEN
IPC: C10C3/02
Filed: 2015-02-06
Granted: 2017-07-11
Abstract: The present invention provides a method for the conversion of asphaltenes to light fractions, including: a process of reacting a hydrogen donor solvent with an asphaltene-containing feedstock, and fractionating reaction products, where a weight ratio of the hydrogen donor solvent to the asphaltene-containing feedstock is 0.1-5:1, a weight hourly space velocity of the reaction is 0.2-5 h-1, reaction pressure is 0.5-25 MPa, reaction temperature is 360-500°C, and the hydrogen donor solvent is a solvent containing polycyclic aromatic compound having a-hydrogen. The method according to the present invention can effectively achieve light fraction conversion of the asphaltenes to light fractions, and the process operation is simple.
Patent CA-2882283-C (CA)
Inventor: PARK GWANG HOON
IPC: H04N19/30
Filed: 2014-07-10
Granted: 2019-03-05
Abstract: The present invention relates to an integrated video encoder/decoder supporting different types of multi-layer images. The integrated video encoder according to the present invention comprises: a basic encoder including an encoding algorithm module for encoding a basic layer image in a multi-layer image; and a partial encoder including an additional encoding algorithm module for encoding an enhanced layer image according to the video coding type of the multi-layer image.
Patent CA-2890902-C (CA)
Inventor: SCHULTZ MICHAEL A
IPC: C12P7/54
Filed: 2013-11-11
Granted: 2017-01-03
Abstract: The invention provides methods and systems for the production of at least one product from the microbial fermentation of a gaseous susbtrate, wherein the gaseous substrate is derived from a biomass liquefaction process. The invention provides a method for improving efficiency of the fermentation by passing biomass accumulated in the fermentation process to the biomass liquefaction process for conversion to a gaseous substrate. In a particular aspect of the invention, the biomass liquefaction process is selected from pyrolysis or torrefaction.
Patent CA-2894132-C (CA)
Title: Cellular layout for semiconductor devices
Inventor: BOLOTNIKOV ALEXANDER VIKTOROVICH
IPC: H01L29/16
Filed: 2015-06-11
Granted: 2023-02-21
Abstract: A method of fabricating a semiconductor device cell at a surface of a silicon carbide (SiC) semiconductor layer includes forming a segmented source and body contact (SSBC) of the semiconductor device cell over the surface of the SiC semiconductor layer. The SSBC includes a body contact portion disposed over the surface of the semiconductor layer and proximate to a body contact region of the semiconductor device cell, wherein the body contact portion is not disposed over the center of the semiconductor device cell. The SSBC also includes a source contact portion disposed over the surface of the semiconductor layer and proximate to a source contact region of the semiconductor device cell, wherein the at least one source contact portion only partially surrounds the body contact portion of the SSBC.
Patent CA-2897516-C (CA)
Title: Method for fractionating soluble fractions of peas, fractions thus obtained and upgrade thereof
Inventor: BARATA MANUEL
IPC: A23J1/14
Filed: 2014-01-31
Granted: 2021-08-31
Abstract: The invention relates to a method for fractionating soluble fractions of peas, including, in sequence, a step of microfiltering or centrifuging, followed by a step of ultrafiltering, and optionally a reverse-osmosis step. A reduction of the leakage of proteins toward the soluble fractions, an improvement of the yield of the single concentration step by evaporating the soluble fractions, and the selective isolation of proteins of interest are thus achieved. The method is easy to implement, the devices used at each single step are conventional and well known to the person skilled in the art. Also, the method of the invention does not use any organic solvent other than water.
Patent CA-2902182-C (CA)
Title: Conducteurs aeriens revetus et procedes
Inventor: RANGANATHAN SATHISH KUMAR
IPC: H01B5/00
Filed: 2014-02-21
Granted: 2019-11-05
Abstract: L'invention concerne un conducteur aérien revêtu présentant un ensemble comportant un ou plusieurs fils conducteurs, de sorte que l'ensemble comprend une surface extérieure revêtue d'un revêtement de dépôt électrochimique formant une couche extérieure, le revêtement de dépôt électrochimique comprenant un premier oxyde métallique, de sorte que le premier oxyde métallique n'est pas de l'oxyde d'aluminium. L'invention concerne également des procédés de fabrication du conducteur aérien.
Patent CA-2905096-C (CA)
Inventor: IANNOTTI JOSEPH P
IPC: A61F2/40
Filed: 2014-03-12
Granted: 2017-12-05
Abstract: An apparatus (100) for facilitating the mounting of a prosthetic articulation surface (548) to a patient tissue includes an anchoring base (102) including a central fastener aperture (106) extending longitudinally therethrough. A first base end (108) is laterally spaced from the central fastener aperture. A second base end (110) is laterally spaced from the first base end with the central fastener aperture laterally interposed therebetween. Both of the first and second base ends include a plate engagement feature (114). An anchor plate (122) includes a central coupler aperture (124) extending longitudinally therethrough. An outer perimeter (126) is spaced laterally apart from the central coupler aperture. A plate rim (128) extends laterally inward from the outer perimeter to substantially laterally surround the central coupler aperture. At least one plate fastener aperture (130) extends longitudinally through the plate rim. At least one base engagement feature (432) is located on the plate rim and is selectively engageable with the plate engagement feature of the anchoring base.
Patent CA-2905134-C (CA)
Title: Gestion et synchronisation de contenu d'une plateforme de partage de document et d'une plateforme sociale d'entreprise
Inventor: RUDKOWSKI MARC
IPC: G06F40/00
Filed: 2015-09-22
Granted: 2016-09-20
Abstract: Linvention concerne des méthodes, des systèmes et des produits de programme informatique conçus pour gérer et synchroniser du contenu entre une plate-forme de partage de documents et une plate-forme sociale dentreprise. Un module de connexion dun dispositif informatique sur serveur reçoit une demande visant la transmission dun ou de plusieurs fichiers entre la plate-forme de partage de documents et la plate-forme sociale dentreprise. Le module de connexion synchronise les fichiers entre la plate-forme de partage de documents et la plate-forme sociale dentreprise. Le module de connexion valide les fichiers pour ce qui est de leur conformité avec un ou plusieurs des éléments suivants : une politique de rétention des documents et une politique de prévention de la perte numérique.
Patent CA-2906015-C (CA)
Inventor: NESNIDAL MICHAEL PAUL
IPC: B64D15/12
Filed: 2015-09-24
Granted: 2022-06-21
Abstract: Un appareil de dégivrage à fil de sonde multifonction est décrit. Lappareil de dégivrage à fil de sonde multifonction peut comprendre un fil de sonde multifonction, un filament chauffant principal contigu avec le fil de sonde multifonction, et un fil sacrificiel adjacent au filament chauffant principal. Le fil sacrificiel est conçu pour céder avant que le filament chauffant principal cède.
Patent CA-2911347-C (CA)
Title: Dessus articule
Inventor: STOUT KENNETH L
IPC: B63B17/02
Filed: 2015-11-05
Granted: 2017-08-01
Abstract: Un cadre pour un dessus dun bateau selon la présente invention peut être déplacé dans une position déployée avec laide dun élément de sollicitation de sorte que leffort manuel requis est minimisé. Lorsque le cadre se trouve dans la position déployée, un élément de verrouillage peut être mis en prise pour tenir le cadre et le dessus dans la position déployée. Lorsque lélément de verrouillage est désaccouplé, le cadre peut être replié manuellement en une position arrimée dune manière contrôlée et sécuritaire.
Patent CA-2913927-C (CA)
Inventor: LIAO HONGWEI
IPC: E21C41/00
Filed: 2015-12-03
Granted: 2019-02-19
Abstract: A system and method for guiding and coordinating vehicular traffic determine tasks to be completed by vehicles in a transportation network in order to complete an objective, allocate the tasks among the vehicles, and determine sets of allowable actions for the vehicles based on the allocation of the tasks. The sets of allowable actions dictate plural different allowable actions that the vehicles are allowed to perform in order to complete the tasks allocated to the vehicles. The allowable actions are determined such that the vehicles are scheduled to complete the tasks and complete the objective without the vehicles colliding or blocking movement of each other. The allowable actions are communicated to the vehicles such that the vehicles are permitted to select one or more of the allowable actions and prohibited from performing one or more other actions during performance of the tasks allocated to the vehicles.
Patent CA-2914274-C (CA)
Inventor: QIN ZHONGBIN
IPC: H04W36/00
Filed: 2014-06-16
Granted: 2022-05-31
Abstract: L'invention concerne un dispositif électronique comprenant un montage de circuits de traitement configuré pour établir un premier canal de communication sans fil avec un équipement d'utilisateur (UE). Le dispositif détermine également si un second canal de communication d'au moins une qualité prédéterminée existe entre l'UE et une station de base non dans la même bande de base (BS) tandis que le premier canal de communication entre l'UE et le dispositif électronique est maintenu. Le premier canal de communication et le second canal de communication utilisent des ressources de porteuse différentes.
Patent CA-2915516-C (CA)
Title: Blasting systems & methods
Inventor: PARK ALLEN
IPC: F42D1/28
Filed: 2014-06-16
Granted: 2021-02-16
Abstract: In one preferred form of the present invention there is provided a method of stemming a blast hole with a super absorbent polymer. The method includes providing a super absorbent polymer substance as a gelled length in the blast hole. The gelled length provides a pressure wave reflecting stem, to increase the efficiency of an explosive during blasting, with the explosive being located in the blast hole.
Patent CA-2917402-C (CA)
Title: Novel dual-targeting protein binding specifically to dll4 and vegf and use thereof
Inventor: LEE DONG HEON
IPC: G01N33/574
Filed: 2014-07-08
Granted: 2019-10-22
Abstract: The present invention relates to a dual-targeted protein comprising: a novel protein specifically binding to delta like ligand 4 (DLL4); and an antibody specifically binding to a vascular endothelial cell growth factor (VEGF).
Patent CA-2917545-C (CA)
Inventor: PURI ANU
IPC: A61P35/00
Filed: 2014-07-09
Granted: 2022-01-11
Abstract: La présente invention concerne des modes de réalisation de nanoparticules à base de lipides photo-activables, ainsi que des procédés de fabrication et d'utilisation des nanoparticules. La présente invention concerne en outre des compositions pharmaceutiques comprenant les nanoparticules. Les nanoparticules à base de lipides comprennent une paroi de vésicule entourant une cavité, la paroi de vésicule comprenant (i) une bicouche de lipides comprenant de la 1,2-bis(tricosa-10,12-diynoyl)-sn-glycéro-3-phosphocholine (DC8,9PC), de la dipalmitoylphosphatidylcholine (DPPC), et (ii) du 2-[1-hexyloxyéthyl]-2-dévinyl-pyrophéophorbide-a (HPPH) dans la bicouche de lipides. Les nanoparticules peuvent comprendre en outre un agent dans la cavité.
Patent CA-2918802-C (CA)
Title: Stylo d'injection
Inventor: CRONENBERG RICHARD
IPC: A61M5/24
Filed: 2014-07-30
Granted: 2022-03-01
Abstract: La présente invention concerne un stylo d'injection (1) qui comprend un logement (2), une vis-mère (75), un élément de définition de dose (6), un élément de recul (17) et un dispositif d'entraînement rotatif (60). La vis-mère (75) est axialement amovible dans le logement (2). L'élément de définition de dose (6) est raccordé au logement (2) pour définir la dose et corriger la dose. L'élément de recul (17) est fonctionnellement raccordé à l'élément de définition de dose (6). Le dispositif d'entraînement rotatif (60) est raccordé à l'élément de recul (17) et à la vis-mère. Le dispositif d'entraînement (60) est empêché de pivoter durant la définition de dose et la correction de dose, et le dispositif d'entraînement (60) pivote durant une injection pour déplacer axialement la vis-mère (75).
Patent CA-2920274-C (CA)
Title: A cargo shipment route determination apparatus and method
Inventor: SCHREIBER ZVI
IPC: G06Q10/08
Filed: 2014-03-10
Granted: 2022-08-09
Abstract: A method comprising: providing data regarding a plurality of shipment services, each datum comprising a service origin and destination pair and price information; providing data regarding a plurality of shipment service providers, each shipment service associated with a shipment service provider; providing a shipment origin and destination of the cargo; responsive to the shipment origin, the shipment destination and a predetermined route viability criterion, identifying a viability set of the shipment services; responsive to a predetermined business relationship criterion, identifying a set of the shipment service providers; responsive to the identified shipment service viability set and the identified provider set, determining, in real- time, a shipment route for the cargo from the provided shipment origin to the provided shipment destination; responsive to the shipment service price information, determining, in real-time, price information associated with the determined shipment route; and outputting the determined shipment route and the determined associated price information.
Patent CA-2921367-C (CA)
Inventor: ARBESMAN RAY
IPC: A61F5/02
Filed: 2016-02-19
Granted: 2022-07-26
Abstract: A method for supporting a body part comprises a) removing a first release liner portion from an adhesive side of an anchor portion of a precut piece of kinesiology tape; b) adhering the adhesive side of the anchor portion to a generally flat surface of the body part; c) removing a second release liner portion from an adhesive side of a finger portion of the precut piece of kinesiology tape, while retaining a finger reinforcement layer on a non-adhesive side of the finger portion; d) after step c), adhering the adhesive side of the finger portion to the generally flat surface, so that the precut piece of kinesiology tape lies generally flat on the generally flat surface; and e) after step d), removing the finger reinforcement layer from the non-adhesive side of the finger portion.
Patent CA-2926141-C (CA)
Title: Conceptions de format de fichier video multicouche
Inventor: WANG YE-KUI
IPC: H04N19/30
Filed: 2014-10-23
Granted: 2019-09-24
Abstract: Selon l'invention, un dispositif informatique génère un fichier qui comprend une case de pistes qui contient des métadonnées pour une piste dans le fichier. Des données multimédias pour la piste comprennent une séquence d'échantillons. Chacun des échantillons est une unité d'accès vidéo de données vidéo multicouche. En tant que partie de la génération du fichier, le dispositif informatique génère, dans le fichier, une case supplémentaire qui récolte des données sur l'ensemble des échantillons contenant au moins une image de point d'accès aléatoire intra (IRAP).
Patent CA-2928513-C (CA)
Inventor: CHI XIAOHENG
IPC: G01B3/1056
Filed: 2013-10-23
Granted: 2021-01-19
Abstract: The present invention discloses a blocking member for the tape end, which comprises a connecting part that extends horizontally and connects with the tape end and a lower blocking member which extends downward from the connecting part, wherein the blocking member further comprises a hook extending upward from the connecting part in order to perform length measurement conveniently for pipelines, wire cables and objects in vertical. The blocking member of the present invention is more stable than a plane hook, when in use, especially measuring a relatively long object, it is more difficult to be taken off, and it is of low cost and does not affect the tapeline assembling. The present invention also provides a tapeline with the aforementioned blocking member.
Patent CA-2928586-C (CA)
Title: Goal post retention device
Inventor: CORBETT ROBERT
IPC: A63B63/00
Filed: 2016-05-02
Granted: 2018-07-10
Abstract: A goal post retention device, comprising a body having a first member and a second member, wherein the first and second members are integral with one another, the first member comprising a first semi-open cylinder having a top planar annular surface, the cylinder having a first outer diameter, the second member arranged beneath and concentric with the first member, the second member comprising a semi-open cylinder having a second outer diameter which is larger than the first outer diameter, the semi-open cylinder having a bottom rim and a frustoconical inner surface extending upwardly from the bottom rim, the semi-open cylinder having a top annular surface. In one embodiment, a spike extends downwardly within the second member, extending slightly below the bottom rim.
Patent CA-2931040-C (CA)
Inventor: GRIES REGINE M
IPC: A01P19/00
Filed: 2014-12-16
Granted: 2023-02-28
Abstract: Disclosed is a six-component composition of volatile and less-volatile pheromone components that can be used alone or in combination with other compounds to attract and/or arrest bed bugs of both sexes and all developmental stages. This blend can be used to bait traps that are effective in capturing bed bugs in infested premises or can be combined with a pesticide that is lethal to bed bugs.
Patent CA-2936762-C (CA)
Title: Passageway to board and deplane an airplane
Inventor: LARSON JAMES
IPC: B64F1/30
Filed: 2016-07-01
Granted: 2023-09-26
Abstract: Passageway including a section that is extendable and retractable, the section including a frame, slide track assemblies, and scissor bar assembly. The frame has upright members. The slide track assemblies are disposed proximately to respective upright members. Each of the slide track assemblies includes a slide track and slide block. The slide track has a cavity and channel. The slide block is configured to ascend, descend, and rotate within the cavity. The slide block includes a guide block that extends from the slide block at least partially through the channel. The scissor bar assembly is secured to the upright members and slide track assemblies such that the upright members are enabled to extend and retract with respect to each other along at least one arcuate path, wherein the guide block limits rotation of the slide block within the slide track to rotation of the guide block within the channel.