baber/WOPTO huggingface dataset:
Patent EA-006785-B1 (EA)
Title: A reactive distillation process for the alkylation of aromatic hydrocarbons
Inventor: WINDER J BARRY
IPC: C07C2/64
Filed: 2003-01-16
Abstract: A unified process for reactive distillation under pressure for the alkylation of light aromatic hydrocarbons such as benzene and cumene with straight chain C- Colefins using a solid acid alkylation catalyst supported in the reflux zone of the distillation column (column 2). The process is continuous, using a reactive distillation configuration such that at least a portion of the olefin (7) is injected below the benzene rectification zone at the top of the column. The aromatic hydrocarbon (17) is injected continuously at a low rate above the rectification zone (H) at the base of the column and above the reboiler (40). The alkylation reaction takes place primarily in the liquid phase on the solid acid catalyst and is characterized in that the molar ratio is adjustable up to about 100/1, through adjustment of the internal column operating pressure, the benzene reflux rate, the amount of benzene removed from the reflux condenser to storage or from the reboiler with the distillation column operated at or near total aromatic hydrocarbon reflux. The unexpectedly high liquid phase aromatic hydrocarbon to olefin molar ratios achieved in the reactive distillation column increases the selectivity to mono-alkylated aromatics and helps stabilize catalyst lifetime.
Patent EA-010417-B1 (EA)
Title: Derivatives of glycinergic r(+)-2-amino-3-hydroxypropanoic acid
Inventor: CLARENCE-SMITH KATHLEEN
IPC: C07C237/12
Filed: 2003-08-01
Abstract: Derivatives of R(+)-2-amino-3-hydroxypropanoic acid nitrogen substituted by a phenyl(C-C) alkenyl, gem-diphenyl(C-C)alkyl other than benzhydryl, gem-diphenyl(C-C)alkenyl, a phenyl(C-C)alkylidene or gem-diphenyl(C-C)alkylidene group, and the pharmaceutically-acceptable salts thereof for the preparation of medicaments that are intended for the treatment of diseases of the CNS due to reduced glycinergic transmission, such as for the treatment of autism, schizophrenia and Alzheimer's disease.
Patent EA-011697-B1 (EA)
Title: Method for air distributing in room
Inventor: OSIPOV SERGEY NIKOLAEVICH
IPC: F24F7/06
Filed: 2006-10-18
Abstract: The invention elates to ventilating and air conditioning and discloses a method for air distributing in room providing a required microclimate parameters in production facilities and recreation areas in air-conditioned building premises and substantial safe of cooled air. The method is characterized in that there created stationary or temporary local air-conditioned volume in production or recreation areas for several people by putting partitions, treated conditioned air is supplied to said volume and used air is exhausted from said local volume or premises, additional partitions are made air low-permeable providing their tight joining to floor and each other by corresponding edges, the height of said partitions or al least one of them does not exceed the upper zone of recreating or working by a human.
Patent EA-012377-B1 (EA)
Title: Solid oral pharmaceutical compositions for once daily dosing containing pregabalin, a matrix forming agent and a swelling agent
Inventor: BOCKBRADER HOWARD NORMAN
IPC: A61K9/20
Filed: 2006-10-23
Abstract: A solid pharmaceutical composition containing pregabalin is described. The composition includes a matrix forming agent and a swelling agent and is suitable for once daily oral administration. Exemplary matrix forming agents include mixtures of polyvinyl acetate and polyvinylpyrrolidone, and exemplary swelling agents include cross-linked polymers of polyvinylpyrrolidone.
Patent EA-014507-B1 (EA)
Title: Training device for sportsmen and children
Inventor: STEPIN PAVEL NIKOLAEVICH
IPC: A63B69/26
Filed: 2007-07-18
Abstract: The invention relates to physical development of human beings, in particular to training devices for boxers or to toys for developing physical abilities of children. With a view to extend functionalities and improve operation conditions of the inventive training device for boxers, said device comprises an impact receiving unit which is connected, by means of a flexible rod, to a mechanism fixable to a sportsman's body. Said impact receiving unit is embodied, for example, in the form of a ball, pear or a pumpkin made from leather which is duplicated with dublerin and is provided with contrast painted inserts sewed therein, a cut and holes for lacing up the unit cavity filled with a shock-absorbing filler. A sealed chamber containing liquid and weight is also arranged in said cavity. The sealed chamber is rigidly connected to the flexible rod, which is embodied in the form of a twisted rubber rope, by means of a synthetic rope passing through an additional leather stripe fixed to the body of the impact receiving unit. The top end of the rubber rope is connected to the mechanism fixable to a sportsman's body, which is embodied in the form of a leather belt provided with a fixing unit, in such a way that it makes it possible to adjust the length thereof.
Patent EA-014995-B1 (EA)
Title: Method for washing laundry in a program-controlled domestic appliance, and corresponding domestic appliance
Inventor: CZYZEWSKI GUNDULA
IPC: D06F39/02
Filed: 2007-12-19
Abstract: The invention relates to a method for washing laundry in a program-controlled domestic appliance for doing laundry. According to said method, the washing liquid present in the tub is heated and a washing temperature is adjusted, parameter values that are specific of the laundry and/or of the appliance being determined and the heating of the washing liquid to adjust a specific washing temperature being carried out according to the parameter values.
Patent EA-018827-B1 (EA)
Title: Sensor grouping for dual sensor marine seismic streamer and method for seismic surveying
Inventor: TENGHAMN STIG RUNE LENNART
IPC: G01V1/38
Filed: 2010-08-24
Abstract: A method for marine seismic surveying includes towing a streamer in a body of water. The streamer includes a plurality of spaced apart sensor groups, each including a plurality of longitudinally spaced apart pressure sensors and particle motion responsive sensors. Signals are detected at each of the sensors in response to actuation of a seismic energy source. Components of the sampled motion signals in each group above a selected frequency are combined to generate respective group motion signals. Components of the motion responsive signals below the selected frequency are velocity filtered. The velocity filtered signals are combined with the group motion signals to generate full bandwidth motion responsive signals corresponding to each sensor group.
Patent EA-018485-B1 (EA)
Title: Sulphur cement pre-composition and process for preparing such sulphur cement pre-composition
Inventor: LANKSHEAR MICHAEL DAVID
IPC: C04B28/36
Filed: 2009-06-10
Abstract: The present invention provides a sulphur cement pre- composition, comprising sulphur and at least an organotitanate, which organotitanate is of the general molecular formula (1) or (2)wherein OR, ORand ORare independently chosen from acyloxy, phosphato, pyrophosphate, sulfonato and glycoxy; and XO and X'O are independently chosen from alkoxy or neoalkoxy group or XO and X'O together form a glycoxy group. The invention further provides a process for preparing such sulphur cement pre-composition, processes for the preparation of a sulphur cement product, a sulphur cement product and the use of such sulphur cement pre-composition. The invention even further relates to the use of an organotitanate stabilizing agent.
Patent EA-034783-B1 (EA)
Title: Alpha-4-beta-7 heterodimer specific antagonist antibody
Inventor: HSU HAILING
IPC: C07K16/28
Filed: 2010-03-16
Abstract: There are disclosed isolated alpha4beta7 heterodimer-specific antigen binding proteins; an isolated nucleic acid encoding said antigen binding proteins; a vector comprising said nucleic acid; an isolated host cell transformed or transfected with said vector. Also disclosed are methods for the production of said antigen binding protein; a pharmaceutical composition for inhibiting at least one activity of alpha4beta7 comprising said antigen binding protein; a method of inhibiting at least one activity of alpha4beta7 and a method of inhibiting adhesion of cells expressing alpha4beta7 to tissues comprising cells expressing MAdCAM-1, comprising contacting a cell expressing alpha4beta7 to said alpha4beta7 heterodimer-specific antigen binding protein; and a method of treating an individual afflicted with a condition characterized by inappropriate trafficking of cells expressing alpha4beta7 to tissues comprising cells expressing MAdCAM-1, said method comprising administering to the individual said pharmaceutical composition.
Patent EA-020266-B1 (EA)
Title: Treatment tank with candle filter tray
Inventor: CACHERO VENTOSA DAVID
IPC: B01D3/32
Filed: 2010-02-10
Abstract: A treatment tank in particular for cleaning liquids and/or gases includes a horizontal tray (3) connected with the tank wall (4), a vertical central beam (1) to which the tray (3) is centrally fixed, and one or more prestressed tension bars (2), which extend from the central beam (1) upward-outside at an angle in the direction of the tank wall (4) and are fixed thereto.
Patent EA-020168-B1 (EA)
Title: Solid dosage form having a choleretic effect (variants)
Inventor: CHELYAEVA ANASTASIYA GENNADIEVNA
IPC: A61K33/06
Filed: 2012-10-04
Abstract: The invention relates to the pharmaceutical industry and medicine and can be used in the creation and administration of solid dosage forms having a choleretic effect. The present invention is aimed at creating an effective solid dosage form having a choleretic effect. In the description, two variants of the invention are claimed which solve the problem of interest in that the solid dosage form contains dried bile, mineral substances and a pharmaceutically acceptable carbon-containing additional substance with carbonC isotopes. The invention achieves the technical results of a greater and more rapid therapeutic effect in the treatment of liver and gall bladder diseases without decreasing the duration of said therapeutic effect or increasing the concentration of bile.
Patent EA-027286-B1 (EA)
Title: Device and method for detecting blood or blood constituents in the liquid system of a device for extracorporeal blood treatment
Inventor: BADO ITKA
IPC: A61M1/16
Filed: 2010-07-31
Abstract: The invention relates to a device and a method for detecting blood or blood constituents in the liquid system of a device for extracorporeal blood treatment, comprising a dialysis device (1) or filter divided by a semipermeable membrane (2) into a first chamber (3) and a second chamber (4), wherein the first chamber (3) is part of the extracorporeal blood circulation system (I) and the second chamber (4) part of the liquid system (II) of the extracorporeal blood treatment device. The device according to the invention for detecting blood or blood constituents in the liquid system of an extracorporeal blood treatment device is designed as a unit for differentiating between the entry of blood into the liquid system due to a defect of the dialysis device or filter, for example a rupture of the semipermeable membrane of the dialysis device or filter, or the entry of hemoglobin into the liquid system due to hemolysis, wherein a differentiation is made between a defect of the dialysis device or filter or hemolysis based on the change in intensity of at least the blue fraction of the light exiting from the liquid.
Patent EA-023291-B1 (EA)
Title: Method for making a catalyst comprising a phosphorus modified zeolite to be used in a mto process
Inventor: NESTERENKO NIKOLAI
IPC: C07C1/24
Filed: 2011-01-25
Abstract: The present invention is a method for making a catalyst in a MTO process to convert an alcohol or an ether into light olefins wherein said catalyst comprises a phosphorus modified zeolite and wherein the method comprises the following steps: a) the essential portion of the phosphorus is introduced into a zeolite comprising at least one ten members ring in the structure, before introducing any other components, b) the phosphorus modified zeolite of step a) is mixed with at least a component selected among one or more binders, salts of alkali-earth metals, salts of rare-earth metals, clays and shaping additives, b)* making a catalyst body from mixture b), c) a drying step or a drying step followed by a washing step, d) a calcination step, d*) a washing step followed by a drying step.
Patent EA-025570-B1 (EA)
Title: Method and device to reduce slosh energy absorption effects by reducing blood flow from the cranium
Inventor: SMITH DAVID
IPC: B64D10/00
Filed: 2011-10-11
Abstract: Venous compression in the neck reduces the extent of axonal injury in a standardized mild TBI model in rodents. The mechanism restricts brain venous drainage and increases the central nervous system blood volume and pressure, thus shifting intracranial physiology to the steep part of the volume-compliance curve. The lack of compliance inside the confines of the skull and spinal canal prevents slosh energy absorption and the resultant axonal injury by causing them to approach a more elastic collision when the skull is struck during the weight drop method. A first embodiment can be a device comprising a means to reduce slosh energy absorption in a fluid containing organism by reducing the flow of one or more outflow vessels of the cranium by compressing said vessels.
Patent EA-027765-B1 (EA)
Title: Growth substrate products and their use
Inventor: HEMPENIUS EELKE GJALT
IPC: A01G31/00
Filed: 2012-05-16
Abstract: The invention provides a multiple density growth substrate product (1) formed of a coherent matrix of man-made vitreous fibres (MMVF) bonded with binder, having an upper surface (2) provided with a recess (3) adapted to receive a seed or seedling and an opposite lower surface (4) on which the product rests when in use, the product being formed of at least two layers including an upper layer (5) positioned at the upper surface and having a first density and a lower layer (6) positioned at the opposite lower surface and having a second density, wherein the first density is less than the second density by at least 5 kg/mand wherein the loss on ignition (LOI) in the upper layer is at least 3.5 wt.%. The invention also provides the use in methods for growing plants, especially pepper plants, of a mono density growth substrate product formed of a coherent matrix of man-made vitreous fibres (MMVF) bonded with binder, having an upper surface provided with a recess adapted to receive a seed or seedling wherein the density of the product is not more than 70 kg/mand the loss on ignition (LOI) is at least 3.5 wt.%.
Patent EA-031771-B1 (EA)
Title: Biological microchip for the quantitative determination of immunoglobulins of e and g levels in biological fluids and method of assay using the same
Inventor: FOOKE-ACHTERRATH MARGRIT
IPC: G01N33/68
Filed: 2011-07-13
Abstract: The invention relates to biochemistry and medicine, more specifically to analytical biochemistry and immunochemical assay, and concerns a hydrogel-based biological microchip for the simultaneous quantitative determination of allergen-specific and total immunoglobulins E and/or immunoglobulins G in biological fluids. The biological microchip comprises elements with various allergens immobilized therein which are capable of causing allergic reactions in humans involving immunoglobulins E and G, and elements with immobilized human immunoglobulins E in different concentrations and elements with immobilized human immunoglobulins G in different concentrations for the construction of internal calibration curves. The invention also relates to a method for carrying out simultaneous quantitative assay of allergen-specific immunoglobulins E and G on the biological microchip using the internal calibration curves. The invention may appear useful in diagnosing and monitoring the treatment of various types of allergies that involve immunoglobulins E and G.
Patent EA-026153-B1 (EA)
Title: Treatment of hematologic malignancies with an anti-cxcr4 antibody
Inventor: KUHNE MICHELLE R
IPC: C07K16/28
Filed: 2012-11-09
Abstract: The present invention provides human monoclonal antibodies that bind specifically to CXCR4 with high affinity. The present invention also provides a method for treating a subject afflicted with a CXCR4-expressing cancer, in particular a hematological malignancy such as multiple myeloma, acute myeloid leukemia, or non-Hodgkin's lymphoma, comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an anti-CXCR4 antibody of the invention. The invention further provides a kit for treating a cancer in a subject comprising a dose of an anti-CXCR4 antibody and instructions for using the anti-CXCR4 antibody in the therapeutic methods of the invention.
Patent EA-026412-B1 (EA)
Title: NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-b]PYRIDINE AND 3,5-DISUBSTITUED-3H-[1,2,3]TRIAZOLO[4,5-b]PYRIDINE COMPOUNDS AS MODULATORS OF C-met PROTEIN KINASES
Inventor: VAKKALANKA SWAROOP KUMAR VENKATA SATYA
IPC: C07D471/04
Filed: 2013-02-27
Abstract: The present invention provides compounds useful as C-met protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of C-met kinase mediated diseases or disorders with them.
Patent EA-029323-B1 (EA)
Title: Process for removing light components from an ethylene stream
Inventor: VERMEIREN WALTER
IPC: C07C7/04
Filed: 2013-12-13
Abstract: The claimed invention is a process for removing light components from an ethylene stream comprising: a) providing a dried ethylene stream (A) comprising ethylene, ethane, CO, CO, H, CH, Chydrocarbons and optionally oxygenates, b) sending said stream (A) to a stripper, also referred to as a demethanizer, to produce an overhead stream comprising ethylene, CO, Hand CH; a bottom stream comprising ethylene, ethane, CO, Chydrocarbons and optionally oxygenates, wherein, the gaseous phase on top of the stripper is condensed in a heat exchanger cooled by a refrigerant stream to get a first gaseous phase and a first liquid phase, the first gaseous phase is condensed in a heat exchanger cooled by liquid ethane or liquid ethylene to get a second gaseous phase referred to as the overhead stream comprising ethylene, CO, Hand CHand a second liquid phase, wherein the first and second liquid phases are the reflux of the stripper.
Patent EA-033792-B1 (EA)
Title: Method for treating cancer using a biocompatible gel comprising nanoparticles and/or nanoparticles aggregates
Inventor: POUL LAURENCE
IPC: A61K49/04
Filed: 2014-06-19
Abstract: The present invention relates to a method for treating cancer in subject comprising the step of treating a target biological tissue of a patient with a biocompatible gel comprising nanoparticles and/or nanoparticles aggregates, wherein i) the density of each nanoparticle and nanoparticles aggregate is of at least 7 g/cm, the nanoparticle or nanoparticles aggregate comprises one metal element or a mixture of metal elements, each metal element has an atomic number Z of at least 40, each of said nanoparticles and of said nanoparticles aggregate is covered with a biocompatible coating; ii) the nanoparticles and/or nanoparticles aggregates concentration is of at least about 1% (w/w); and iii) the apparent viscosity at 2sof the gel comprising nanoparticles and/or nanoparticles aggregates, is between 5 and 750 Pa∙s when measured between 20 and 37°C, wherein the nanoparticles and/or nanoparticles aggregates of said gel define the delineation of the target biological tissue, and the step of irradiating the delineated target biological tissue; also disclosed are a kit for use in the method and the use of said kit for preparing a biocompatible gel.
Patent EA-037559-B1 (EA)
Title: Hexahydropyrazinotriazinone derivatives as kinase inhibitors
Inventor: HORSLEY HELEN TRACEY
IPC: C07D487/04
Filed: 2016-12-08
Abstract: Described herein is a series of 1,2,6,7,9,9a-hexahydropyrazino[1,2-d][1,2,4]triazin-4-one derivatives of formula (I)substituted in the 8-position by an optionally substituted fused bicyclic heteroaromatic group, and in the 3-position by a range of functional groups, being selective inhibitors of phosphatidylinositol-4-kinase III (PI4KIII) activity, beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases and malaria; and organ and cell transplant rejection.
Patent EA-038609-B1 (EA)
Title: Powdered antimicrobial agent for preparing solution for topical and external use, method for production and use thereof
Inventor: LAZAREVA YULIA YURIEVNA
IPC: A61P31/02
Filed: 2018-10-31
Abstract: The invention relates to the field of medicine and disinfection, in particular, to powdered antibacterial (antimicrobial) agent used to prepare a solution for topical and external use, containing Furacilin (nitrofural, 2-[(5-nitro-2-furanyl)methylene]hydrazine carboxamide as an active substance, sodium salts as an excipient; and to the method of its production and application for solution preparation. Provided is a powdered agent used to prepare a solution for topical and external use, comprising furacilin (nitrofural) as an active ingredient, and sodium salt as an excipient, at the following ratio of the said components to obtain an isotonic solution, wt.%: nitrofural (furacilin) - 1.5-2.5; sodium salt - 97.5-98.5. The claimed agent is characterized by improved solubility, efficiency, stability and ease of use of the solution obtained.
Patent EA-037766-B1 (EA)
Title: Sulphated hyaluronic acids functionalised with dopamine
Inventor: GUARISE CRISTIAN
IPC: C08B37/08
Filed: 2017-11-13
Abstract: Disclosed is grade 2 sulphated hyaluronic acid having 2 to 60 mol %, preferably 15 to 35%, and even more preferably between 20 and 25%, of the carboxyl groups functionalized with dopamine conjugated directly via an amide bond or by means of a spacer having an amino group for the formation of an amide bond with the carboxyl groups of hyaluronic acid and of a carboxyl group for the formation of an amide bond with the amino group of dopamine.
Patent ES-2194568-B1 (ES)
Title: Artefacto de golpeo ajustable a la palma de la mano.
Inventor: COLODRON SESEMANN LOIC
IPC: A63B71/14
Filed: 2001-01-08
Granted: 2005-02-16
Abstract: Artefacto de golpeo ajustable a la palma de la mano. Consiste en un artefacto de golpeo ajustable a la palma de la mano según Fig.1 compuesto por una semi-manopla que envuelve a la mano y se ajusta a ella y a la muñeca, llevando sujetas dos superficies de golpeo en dorso e interior de la mano, convirtiendola en instrumento de golpeo y facilitando la práctica de variantes de deportes de raqueta y/o palas, como frontón, paddle-tenis y otros, dependiendo de la pelota adecuada para pista y artefacto, e incluso manteniendo las mismas reglas. Existen diversas formas de lograr el ajuste a muñeca y mano, así como variadas opciones para configurar las superficies de golpeo.
Patent ES-2241404-B1 (ES)
Inventor: GRACIA BOBED ISMAEL
IPC: D06F37/20
Filed: 2002-11-06
Granted: 2006-07-01
Abstract: The attachment system has at least one attachment element (3') on the container (6') for at least one attachment arrangement (2') for the motor and a forward balance weight (9') in the container. The motor has at least one attachment arrangement (12) corresponding to at least one attachment element (13) on the forward balance weight. The balance weight protrudes down below the lower part of the container to form an attachment element for the motor.