baber/WOPTO huggingface dataset:
Patent NZ-500447-A (NZ)
Title: Substituted imidazoles that inhibit cytokine production and are useful in the treatment of inflammatory disease
Inventor: MALLOY ELIZABETH A
IPC: A61P29/00
Filed: 1998-04-17
Abstract: Compounds of formula I wherein,  R1 is phenyl, substituted phenyl (where the substituents are C1-5alkyl, halogen, nitro, trifluoromethyl, and nitrile), or heteroaryl where the heteroaryl contains 5 to 6 ring atoms;  R2 is phenyl, substituted phenyl (where the substituents are C1-5alkyl, halogen, nitro, trifluoromethyl, and nitrile), heteroaryl where the heteroarylcontains 5 to 6 ring atoms and is optionally C1-4alkyl substituted; R3 is hydrogen, SEM, C1-5alkoxycarbonyl, aryloxycarbonyl, arylC1-5alkyloxycarbonyl, arylC1-5aIkyl, substituted arylC1-5alkyl (where the aryl substituents are independently selected from one or more of C1-5alkyl, C1-5alkoxy, halogen, amino, C1-5alkylamino, and diC1-5alkylamino), phthalimidoC1-5alkyl, aminoC1-5alkyl, diaminoC1-5alkyl, succinimidoC1-5alkyl, C1-5alkylcarbonyl, arylcarbonyl, C1-5alkylcarbonylC1-5alkyl, aryloxycarbonylC1-5alkyl, heteroarylC1-5alkyl where the heteroaryl contains 5 to 6 ring atoms; R4 is (A)-(CH2)q-X where: A is vinylene, ethynylene or formula II where, R5 is selected from the group consisting of hydrogen, C1-5alkyl, phenyl and phenylC1-5alkyl; and q is 0-9, and X is as listed in the specification. The pharmaceuticals compositions containing compounds of formula I inhibit the production of a number of inflammatory cytokines (TNF-a and IL-1b), and are useful in treating disease with overproduction of inflammatory cytokines.
Patent NZ-500789-A (NZ)
Title: Analogs of duocarmycin and CC-1065
Inventor: BOGER DALE L
IPC: A61P43/00
Filed: 1998-05-22
Abstract: The compounds shown are analogues of duocarmycin and CC-1065, and are useful for alkylating DNA and for treating tumours.
Patent NZ-503777-A (NZ)
Title: Production of cellular concrete (foamcrete) units for use in arresting bed systems designed to decelerate large moving objects, e.g. aircraft
Inventor: CIESIELSKI MICHAEL S
IPC: B64F1/02
Filed: 1998-02-06
Abstract: Vehicle arresting blocks of cellular concrete are usable to safely slow travel of an object and are used to construct an aircraft arresting bed at the end of an airport runway. For such purposes, cellular concrete blocks are fabricated to exhibit compressive gradient strengths of predetermined values to provide sufficient, but not excessive, deceleration forces on an object. Material uniformity characteristics must be met to avoid unacceptable drag force variations, so that arresting blocks exhibit a predetermined compressive gradient strength (e.g., a 60/80 CGS) over a depth of penetration of 10 to 66 percent of block thickness. A 60/80 CGS will typically represent an average compressive strength of 70 pounds per square inch over such depth of penetration. Methods described include parameter, ingredient and process controls and ranges effective to enable fabrication of arresting blocks having dry densities and compressive gradient strengths which can be specified in order to provide limited deceleration of aircraft and other large objects. Limited deceleration can avoid destructive effects inherent in excess rates of deceleration. One method for forming a section of a deceleration block to provide limited deceleration of a moving object comprises steps of: 1. forming a slurry of cement and water; 2. preparing a foam from water and a foaming agent; 3. admixing the slurry and foam to provide a cellular concrete; 4. placing a portion of the cellular concrete in a form to provide the deceleration block in a shape and size suitable for use in decelerating a moving object and; 5. including within the lower portion of the cellular concrete form a layer of material of higher strength than the cellular concrete after curing and the layer positioned so as not to interfere with the compressive failure of the block to a depth of penetration of 80 percent of the block thickness.
Patent NZ-505914-A (NZ)
Title: Three-dimensional structures and models of fc receptors and uses thereof
Inventor: HOGARTH MARK P
IPC: G06T19/00
Filed: 1999-02-04
Abstract: A computer-assisted method of structure based drug design of bioactive compounds comprises: providing a model of an Fc receptor (FcR) protein, wherein the model represents a three dimensional structure that conforms to the atomic coordinates selected from the group consisting of atomic coordinates represented by Table 1-5, designing a chemical compound using the model and then chemically synthesizing the compound. Also described are therapeutic composition for enhancing IgG-mediated responses comprising the three-dimensional structure of an FcR protein with reference to the atomic coordinates represented in any one of Tables 1 to 5, and a computer for producing a three- dimensional model of a molecule or molecular structure comprising a computer-readable medium, a working memory, a processor and a display.
Patent NZ-506895-A (NZ)
Title: Corticotropin releasing factor receptor 1-deficient mice
Inventor: LEE KUO-FEN
IPC: C12N15/09
Filed: 1999-03-30
Abstract: A transgenic mouse whose somatic and germ cells have  a substantial deficiency in the corticotropin releasing factor receptor-1, wherein one or both alleles of the corticotropin releasing  factor receptor-1 are disrupted  resulting  in  a mouse with decreased anxiety, reduced endocrine response  to stress and altered locomoter activity rhythms as compared to a  control  mouse.  Also covered are methods of  using  said mouse   for   identifying  agonists   and   antagonists   of corticotropin releasing factor, urocortin or related ligands that   act   through  receptors  other  than   corticotropin releasing  factor  receptor-1, offspring  from  said  mouse, using offspring from said mouse to screen compounds that are analogs  of corticosterone or corticotropin and a method  of producing said transgenic mouse.
Patent NZ-514617-A (NZ)
Title: Betting means where the winnings are distributed equally amongst bettors in the betting pool
Inventor: TURNER MAPUNA
IPC: G07F17/32
Filed: 2001-10-04
Abstract: A computer program means is arranged to enable a method of processing bets. There is a processing means that includes a record of the number of gambling events, where each event is divided into a number of event pools. The processing means also receives details of competitors competing in each event. A collective of bettors is also received, where each collective comprises a plurality of bettors. The details of the pools that the collective chooses to bet in is then inputted into the processing means. When a respective gambling event concludes, the computer program means calculates the winnings for each collective and distributes the winnings equally within the collective. Alternatively, the winnings are distributed in proportion to the amount of betting money by each bettor in the collective.
Patent NZ-514910-A (NZ)
Title: Regeneration and genetic transformation of acacia mangium
Inventor: XIE DEYU
IPC: A01H5/00
Filed: 2000-01-19
Abstract: The present invention is directed to a method of Acacia mangium regeneration through organogenesis and a method of genetic transformation of Acacia mangium . The method of regeneration comprises inducing callus from different parts of seedlings and vegetatively micropropagated plantlets as explants; culturing on TDZ for adventitious bud induction followed by pinnate leaf and bud elongation and eventually, elongated shoots were induced to root. Based on the regeneration system, a marker gene GUS under cauliflower mosaic virus promoter was introduced to Acacia mangium via Agrobacterium infection. GUS staining in the regenerated plants and Southern blot hybridization prove the incorporation of the foreign gene into the host genome and expression of the foreign gene.
Patent NZ-518830-A (NZ)
Title: Novel compounds to treat diabetes and associated conditions
Inventor: NEOGI PARTHA
IPC: A61K31/216
Filed: 2000-11-08
Abstract: Compounds of formula (I) are provided that lower blood glucose concentrations, lower serum triglyceride concentrations, lower systolic blood pressure, and increase glucose uptake by adipose tissue, but do not affect the expression of PPAR- gamma by adipose tissue.
Patent NZ-520150-A (NZ)
Title: Suction head, core bit and extension piece for dry drilling
Inventor: VANAUDENAERDE FRANK
IPC: B23B51/04
Filed: 2002-07-12
Abstract: A suction head, core bit and extension piece designed to be fitted together with co-operating nut featuring a movement resisting means.
Patent NZ-521168-A (NZ)
Title: Regulation of gaming systems using a smart card that limits the value stored in the card based on actual time
Inventor: SZEWACH ELIK
IPC: G06F17/00
Filed: 2001-02-22
Abstract: A system for regulating gambling and a smart card for use in the system which includes (a) identifying a person; (b) issuing a person with a smart card having clock means or clock reader means with the capability of determining a time period and having a purse associated with the clock or clock reader being able to limit an electronic value input and/or output from the purse on the smart card for a predefined period; (c) setting a maximum input and/or output limit for a predefined period; (d) providing one or more gaming venues having card readers able to interact with the smart cards; and (e) providing linkage to financial sources for electronically transferring verifiable funds to the smart card which are able to be selectively transferred to a gaming venue when the user wishes to undertake a gambling activity; whereby the person can use the smart card to undertake gambling at regulated gambling establishments and have the total amount of accessible funds limited throughout all the regulated gambling establishments for a set period.
Patent NZ-522423-A (NZ)
Title: Wind power plant with a particle sensor
Inventor: WOBBEN ALOYS
IPC: F03D80/00
Filed: 2001-03-02
Abstract: The invention relates to a wind power plant, comprising at least one sensor for detecting the number and/or speed and/or momentum of particles which strike the sensor (1), and a data processing and control device for processing the measuring data detected by the sensor. The speed of the rotor of the wind power plant is reduced and/or the wind power plant is stopped when a particle measurement taken by the sensor is exceeded.
Patent NZ-523035-A (NZ)
Title: Drink dispensing device and container for drink provided with positioning means
Inventor: MAGERMANS MARCEL PETER
IPC: B67D1/00
Filed: 2001-06-11
Abstract: An assembly of a container (1) for drink and a drink dispensing device (11), each of which is provided with positioning means (13, 13'; 16, 16') for orientation of an air connector (20, 48) and a dispensing opening (4) of the container (1) with an air channel (22) and a dispensing line (5) in the lid (25) of the dispensing device (11).
Patent NZ-525340-A (NZ)
Title: Herd control using intra vaginal devices having transmitter and receiver therein
Inventor: BUNT CRAIG ROBERT
IPC: A01K29/00
Filed: 2001-10-25
Abstract: A powered intra-vaginal device fitted to a herd animal, such as a cow, with the ability to carry out the following: - a) Sense an important characteristic of the animal (such as oestrus), b) Dispense an active agent, c) Report on the release of the active agent, d) Communicate with at least one other intra-vaginal device in mutual proximity, and e) Communicate either directly or indirectly with a control unit external to the herd. The intra-vaginal device by itself or via communication with another intra-vaginal device and/or the control unit can be used to administer an agent. Using an example characteristic such as oestrus the device may administer an agent to suppress or encourage oestrus within the animal so that oestrus can be synchronized throughout the entire herd.
Patent NZ-525701-A (NZ)
Title: Molded objects
Inventor: HARTNETT JAMES J
IPC: C08K3/00
Filed: 2001-12-03
Abstract: Disclosed herein is a composition prepared by forming a mixture comprising, on the basis of parts by weight per hundred of elastomer or rubber, phr: (a) 100 phr of a mixture comprising vulcanizable elastomers, styrene-butadiene copolymers and butadiene-acrylonitrile copolymers and at least one thermoplastic polymer or thermoplastic elastomer comprising polyvinyl chloride; (b) from about 150 phr to about 500 phr of at least one mineral filler; (c) from about 0.1 phr to about 10 phr of at least one pigment or colorant; (d) at least one vulcanizing agent in sufficient quantity to substantially fully vulcanize the vulcanizable elastomer; and (e) from about 0.01 to about up to about 10 phr of at least one odor masking agent; wherein upon vulcanization the composition has the look and feel of natural clay. The mineral filler includes a significant amount of clay, the colorant includes red iron oxide and the odor masking agent, when used, is an extract of vanilla. The composition can be molded and, after the addition of other suitable ingredients, can be vulcanized, thereby producing an object having the look and feel of natural clay, but having improved low temperature and mechanical stability. Molded objects made from the composition such as plant pots and saucers, wine bottle coolers, trivets, and other objects that typically are made from natural terra cotta or clay, have aesthetically pleasing characteristics as well as improved properties.
Patent NZ-529968-A (NZ)
Title: Sustained-release composition comprising lactic acid-glycolic acid copolymer and process for producing the same
Inventor: YAMAMOTO KAZUMICHI
IPC: A61K38/08
Filed: 2002-06-28
Abstract: Disclosed herein is a sustained-release composition which contains a physiologically active substance of a LH-RH derivative in a high content, and a lactic acid-glycolic acid polymer which even when gelatin is not included, suppresses its initial excessive release and, thus can achieve a stable release rate over about one month. The polymer having a ratio of weight average molecular weight to number average molecular weight of about 1.40 to 1.90, a weight average molecular weight of about 8,000 to 15,000 and a molar ratio of lactic acid to glycolic acid of from up to but not including 100:0 to about 40:60. The polymer is prepared by adding water to an organic solvent containing a lactic acid-glycolic acid polymer having a weight average molecular weight of about 5,000 to 15,000 at a ratio of about 10 to about 45 (ratio by volume) relative to 100 of the organic solvent. The composition is useful for preventing or treating prostate cancer, prostatomegaly, endometriosis, hysteromyoma, metrofibroma, precocious puberty, dysmenorrheal and breast cancer.
Patent NZ-533023-A (NZ)
Title: Production of ammonium salts of aromatic carboxylic acids
Inventor: KLOPP INGO
IPC: C07C63/08
Filed: 2002-12-03
Abstract: A process for preparing ammonium salts of aromatic carboxylic acids by reacting an aromatic carboxylic acid with ammonia in an aprotic solvent, which comprises carrying out the reaction in a closed vessel by continuously introducing a solution of the aromatic carboxylic acid in the aprotic solvent and passing in gaseous ammonia so that an ammonia partial pressure in the range from 0.1 to 3 bar is maintained in the gas space of the vessel, and discharging a suspension of the ammonium salt in the aprotic solvent.
Patent NZ-534819-A (NZ)
Title: Spat retention, apparatus therefor and related methods
Inventor: BLACKBURN ANDREA JANE
Filed: 2003-04-30
Abstract: Apparatus suitable for spat retention. The apparatus comprises a support (2), a structure (1) rotatably mounted from the support so as to be at least partly immersed in salt water, and a drive (7, 8, 9) to rotate the structure, the structure being adapted to retain spat yet be flushed by salt water. (62) Divided Out of 518786
Patent NZ-536509-A (NZ)
Title: Cable safety system for roadway vehicle impact with cables maintained with support posts for longer periods of time during impact
Inventor: BERGENDAHL PETER
IPC: E01F15/06
Filed: 2003-05-23
Abstract: A safety system including cables and support posts is provided. The safety system may be used to prevent vehicles from impacting with an associated roadside hazard. The safety system will typically maintain engagement between associated cables and support posts for a longer period of time as the posts are bent during a vehicle impact.
Patent NZ-537912-A (NZ)
Title: Use of preptin for the treatment and/or prophylaxis of bone conditions
Inventor: REID IAN REGINALD
IPC: A61K38/18
Filed: 2003-07-31
Abstract: Preptin can be used to treat bone conditions associated with breakdown of bone tissue or bone loss, and to increase or maintain bone density.
Patent NZ-544869-A (NZ)
Title: Closure for collapsible container
Inventor: BROWN SCOTT LINDSAY
IPC: B65D1/02
Filed: 2004-06-25
Abstract: A closure (1) for a collapsible fluid container (2, 3) is disclosed. The closure includes an outer cap (4) having at least one vent opening, an inner float seal (5), an edge seal (6) and a shoulder seal. In use, the closure is attached to the container, and if the container is forcibly collapsed, air is driven between the top edge (7) of the neck (8) of the container and the underside of the edge seal, then between the edge seal and top surface (9) of the outer cap to escape through the vent opening(s) (14) to outside the closure; further depression of the container forces material within the container to urge a bowl (10) of the inner float seal upwards, forcing the edge seal against the outer cap, preventing the material from escaping; releasing the container creates a vacuum effect which draws the inner float seal toward the container and the shoulder seal to seal against the top edge of the neck of the container, so then the outer cap can be tightened on the container, holding the shoulder seal against the top edge of the neck and the edge seal against the outer cap, forming a double seal.
Patent NZ-546760-A (NZ)
Title: Alcoholic beverage dispensing appliance with gas connection
Inventor: GRIMWADE STEPHEN J
IPC: B67D1/04
Filed: 2004-10-22
Abstract: Disclosed is an alcohol beverage dispensing appliance. The appliance has an alcoholic beverage container housed within, and a tap adapter (38) mounted to the container for dispensing beverage from the container. The tap adapter has a first gas connector (88) and a gas line (56) adapted for connection with the container for charging the container with pressurized gas to facilitate beverage dispensing. The tap adapter has at least one gas connecting locating member (90). The appliance has a gas supply line (58) housed in the container that has a second gas connector (86) adapted for sealing engagement with the first gas connector. The appliance has a guideway (64) for locating the second gas connector that is adapted for receiving the gas connecting locating member of the tap adapter in sliding and guiding relation to permit movement of the first gas connector into sealing relation with the second gas connector. The appliance has a locking member (96) moveable in the guideway between an unlocked position permitting movement of the locating member along the guideway and a locked position engaging the locating member to prevent reversing movement of the gas connecting locating member out of the guideway.
Patent NZ-547276-A (NZ)
Title: Method for producing tiotropium salts, tiotropium salts and pharmaceutical formulations, containing the same
Inventor: BANHOLZER ROLF
IPC: C07D451/10
Filed: 2004-10-29
Abstract: The disclosure provides a method for producing tiotropium salts of formula (I), wherein X¯ represents an anion, crystalline form of tiotropium salts as such, pharmaceutical formulations, containing the salts and the use thereof for producing a medicament for the treatment of respiratory tract diseases, in particular, for the treatment of chronic obstructive pulmonary disease (COPD) and asthma.
Patent NZ-550107-A (NZ)
Title: Aqueous composition which comprises an antidiabetic drug and minerals obtained from the igneous rocks kakuhanseki and / or taichoseki
Inventor: NAITO HARUSUKE
IPC: A61K33/24
Filed: 2005-03-01
Abstract: Disclosed is a water-based product comprising: enhanced water wherein the enhanced water has been prepared by exposing water to enhancing media that comprises at least one source of silica selected from sand or quartz sand, a material that generates a magnetic field, a far infrared emitting material, and an igneous rock selected from kakuhanseki or taichoseki and wherein the water based product further comprises at least one agent used to treat diabetes. The enhanced water itself having any one or combination of the following properties: increased wetness; greater solubility of solids, liquids, and gases in the enhanced water; presence of trace minerals selected from the group consisting of silica, magnesium, yttrium, vanadium, and titanium; or the presence of stabilised negative ions. Also disclosed is the use of enhanced water as prepared above for the formulation of a medicament for reducing the insulin requirement of a diabetic patient, wherein the patient is administered at least four eight ounce glasses of the enhanced water daily.
Patent NZ-553684-A (NZ)
Title: A heater
Inventor: BRIGHTON KEVIN
Filed: 2007-03-08
Abstract: A heater 10 including a housing 12, the housing 12 defining a heating chamber 24 and a heating element 26 mounted within the heating chamber 24. The heating element 26 includes a heating core 28 longitudinally extending through heating chamber 24 and a fin 32 extending outwardly from the core 28 at an angle to vertical when the heater 10 is in its in-use orientation.
Patent NZ-554577-A (NZ)
Title: Sink with tracks for sliding accessories
Inventor: YU JAMES
Filed: 2007-04-18
Abstract: A sink 2 including at least one pair of parallel tracks 30 capable of receiving a first sliding accessory 52 which can slide along the tracks. A second pair of parallel tracks 32 running below tracks 30 permits a second sliding accessory that can run beside or underneath the accessory above it if required.
Patent NZ-554696-A (NZ)
Title: Method and apparatus for optimizing variable liquid temperatures
Inventor: HU RUGUO
IPC: A47J31/00
Filed: 2005-11-04
Abstract: An apparatus for optimizing variable liquid temperatures within a beverage machine is disclosed. The apparatus comprises a heating unit (160) for heating a liquid flowing therethrough; a power supply (170) for activating the heating unit; an electronic controller (140) for variably controlling an input power supplied to the heating unit by the power supply; feedback means for providing sensed data to the electronic controller, and the input power is varied by the electronic controller in response to the sensed data in accordance with a profile that represents a predetermined heating level. The profile is selectable from a group of differing profiles with each the differing profile relates to a beverage type and the sensed data includes time of day and fluctuations in supply voltage of the power supply.
Patent NZ-555137-A (NZ)
Title: Therapeutic agent for glaucoma comprising (S)-(-)-1-(4-fluoro-5-isoquinolinesulfonyl)-2-methylhomopiperazine
Inventor: SUGIMOTO SHIN
IPC: A61K31/551
Filed: 2005-12-22
Abstract: Provided is a preventive or therapeutic agent for glaucoma, or preventive or therapeutic agent for ocular hypertension, or relevant eye-drops, comprising (S)-(-)-1-(4-fluoro-5-isoquinolinesulfonyl)-2-methylhomopiperazine or its salt and phosphoric acid or its salt.
Patent NZ-555641-A (NZ)
Title: Stabilisation of glucocorticoid esters with acids
Inventor: MERTIN DIRK
IPC: A61K31/573
Filed: 2005-12-03
Abstract: A nonaqueous fluid pharmaceutical comprising a glucocorticoid ester and an acid wherein the preparation does not contain any protic solvents or dispersents. Preferably the glucocorticoid ester is dexamethasone acetate or betamethasone valearte and the acid is sorbic acid, stearic acid or propionic acid. The pharmaceutical composition demonstrates increased stability of the glucocorticoid ester and is used as a topical application for veterinary medicine.