baber/WOPTO huggingface dataset:
Patent AU-2013201895-A1 (AU)
Title: Hypophosphorous acid derivatives and their therapeutical applications
Inventor: SELVAM CHELLIAH
IPC: A61K31/662
Filed: 2013-03-25
Abstract: HYPOPHOSPHOROUS ACID DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS Abstract Hypophosphorous acid derivatives having Formula (I) wherein M is a [C(R3,R4)]nl - C(E,COOR1, N(H, Z)) group, or an optionally substituted o Ar-CH(COOR1, N(H, Z)) group, or an a, B, or a 3, g-cyclic aminoacid; . R1 is H or R, IR- R being an hydroxy or a carboxy protecting group; . Z is H or an amino protecting group 2 - P-M R', benzyl oxycarbonyl, benzyl or benzyl substituted; . E is H or a C1-C3 alkyl, aryl, an hydrophobic group;. R2 is selected in the group comprising: D-CH(R)- C-(R7 , Rs), OH (Rt,R12)CH- C(R9, Rio), D - CH(OH), D- [C(R13, R14)] 3 -, C[(R15, R16, R17)]. 4, D-CHz, (Ri8)CH = C(R19), D-(Mi), 6 -CO, Formula (II), PO(OH)2-CH2 or (PO(OH) 2-CH2), (COOH-CH2 )-CH 2 , with - D = H, OH, OR, (CH 2 ),2OH, (CHL2 ). 1 OR, COOH, COOR, (CH2).ZCOOH, (CHI2) 1COOR, SR, S(OR), SO2R, NO2 , heteroaryl, C1-C3 alkyl, cy cloalkyl, heterocycloalkyl, (CH2), 2-alkyl, (COOH, NH2)-(CH 2)ui-cyclopropyl-(CH2)1 -, CO-NH-alkyl, Ar, (CH2). 2-Ar, CO-NI-Ar; - R3 to Rig being H, OH, OR, (CH2),2OH, 0 (CH2 ).1OR, COOH, COOR, (CHz),COOH, (CH2) 1COOR, CI-C 3 alkyl, cycloalkyl, (CH2)nl-alkyl, aryl, (CHz)nt-aryl, halogen, CF3, S03H, (CH2)x PO3 H2, with x = 0, 1 or 2, B(OH) 2 , Formula (III), NO2 , SO 2NH 2 , SO2NHR; SR, S(O)R, SO 2R, benzyl; - M1 is an alkylene or arylene group; - nl= 1, 2 or 3, n2= 1, 2 or 3, n3= 0, 1, 2 or 3 and n4- 1, 2 or 3, n5= 1,2 or 3, n6= 0 or 1, u1 and u2, identical or different = 0,1 or 2, with the proviso that Formula (I) does not represent the racemic (3R, S) and the enantiomeric form (3R) of 3 amino,3-carboxy-propyl-2'-carboxy-ethylphosphinic acid; 3 N-N amino,3-carboxy-propyl- 4'carboxy,2'carboxy-butanoylphosphinic acid; 3 amino,3-car boxy-propyl- 2'carboxy-butanoylphosphinic acid; 3 amino,3-carboxy-propyl- amino, 3'carboxy-propylylphosphinic acid; and 3 anino,3-carboxypropyl -7'amino-2', 7-dicarboxyheptylphosphinic acid, said hypophosphorous acid derivatives being diasteroisomers or enantiomers. Application as drugs.
Patent AU-2013202589-A1 (AU)
Title: MicroRNA molecules
Inventor: LAGOS-QUINTANA MARIANA
IPC: A61K38/00
Filed: 2013-04-05
Abstract: F:1IDPERffMPMe.PickCmSchalo407SnIV ,aadw 11700 In Caenorhabditis elegans, lin-4 and let-7 encode 22- and 21 -nucleotide RNAs, respectively, that function as key regulators of developmental timing. Because the appearance of these short RNAs is regulated during development, they are also referred to as "small temporal RNAs" (stRNAs). We show that many more 21- and 22-nt expressed RNAs, termed microRNAs, (miRNAs), exist in invertebrates and vertebrates, and that some of these novel RNAs, similar to let-7 stRNA, are also highly conserved. This suggests that sequence-specific post-transcriptional regulatory mechanisms mediated by small RNAs are more general than previously appreciated.
Patent AU-2013205321-A1 (AU)
Title: Surgical saw having a blade bar and an elongate rod allowing for attachment/removal of the blade bar
Inventor: COSGROVE LIAM C
IPC: A61B17/14
Filed: 2013-04-11
Abstract: Abstract The present disclosure relates to a surgical saw for use with a blade assembly having a blade bar, at least one drive rod moveably disposed within the blade bar and a blade head that is oscillated by the at least one drive rod. The saw comprises a housing including a head, the head having an exposed planar surface for receiving the blade bar; a motor disposed in the housing; an oscillating drive assembly mounted to said housing head that includes at least one drive member that is moveably mounted to said head that extends above the planar surface, said oscillating drive member shaped to receive the at least one drive rod, wherein said oscillating drive assembly is connected to said motor and configured to, upon actuation of the motor, oscillate the at least one drive member so that the oscillation of the at least one drive member results in the reciprocation of the at least one drive rod; and a coupling member separate from the oscillating drive assembly, the coupling member being moveably mounted to the housing head so as to extend above the planar surface, said coupling member being shaped to extend at least partially over the blade assembly blade bar and having a locked state in which said coupling member presses against the blade bar to hold the blade bar to the planar surface and a load state in which the coupling member allows the insertion/removal of the blade bar from the planar surface; and a manually actuated control member moveably attached to the housing head and connected to said coupling member for moving the coupling member between the locked and load states. CD' -4
Patent AU-2013215534-A1 (AU)
Title: Surgical instrument with distal bearing assembly
Inventor: O'BRIEN II TODD SHAY
IPC: A61B17/32
Filed: 2013-01-23
Abstract: A surgical cutting instrument comprises an outer tubular member having a proximal section, an intermediate section and a central lumen. An inner tubular member is rotatably received within the central lumen and includes a distal end forming a cutting member extending distally beyond, and exposed relative to, the distal section of the outer tubular member. A bearing assembly is coupled to the outer tubular member and the inner tubular member.
Patent AU-2013217093-A1 (AU)
Title: Direction active projection
Inventor: CHAPMAN STEVEN R
IPC: E01F9/615
Filed: 2013-02-06
Abstract: A directionally active projection device is described that includes a planar display providing a pattern of information. The planar display includes regions of light transparency and regions for blocking light transmittance. The directionally active projection device also includes a lens arranged adjacent to the planar display, and a collection of light sources arranged as an array in a focal plane of the lens. Also described are methods of controlling directionally active projection devices.
Patent AU-2013220339-A1 (AU)
Title: Platinum/palladium zeolite catalyst
Inventor: TISSLER ARNO
IPC: B01J29/068
Filed: 2013-02-18
Abstract: The invention relates to a method for producing a bimetallic catalyst containing palladium and platinum on a zeolitic carrier material, to a bimetallic catalyst that can be obtained by means of the method, and to the use of the catalyst in oxidation catalysis.
Patent AU-2013237424-A1 (AU)
Title: Vaccine against RSV
Inventor: RADOSEVIC KATARINA
IPC: A61P31/14
Filed: 2013-03-21
Abstract: The invention provides a vaccine against respiratory syncytial virus (RSV), comprising a recombinant human adenovirus of serotype (26) that comprises nucleic acid encoding a RSV F protein or immunologically active part thereof.
Patent AU-2013237711-A1 (AU)
Title: Gasification system for carbon containing fuel
Inventor: ISHIGA TAKUYA
IPC: C10K1/02
Filed: 2013-10-04
Abstract: {Abstract of the disclosure} A gasification system for carbon-containing fuel comprising: a gasifier for gasifying carbon-containing solid fuel and generating syngas, and a fuel feed 5 system for transferring the carbon-containing solid fuel from a coal hopper into the gasifier by gas, wherein: the gasifier is structured so as to take out the syngas generated by gasifying the carbon-containing fuel from above the gasifier, convert inorganic 10 material included in the carbon-containing fuel to fused slag, and take it out below the gasifier, and the gasification system further comprising: a dust removing part installed on a downstream side of the gasifier for removing dust from the syngas taken out from above the 15 gasifier, a char hopper for collecting char from which dust removed by the dust removing part and is accompanied with the syngas, a char feed system for transferring the char collected by the char hopper from the char hopper to the gasifier by gas, a water washing 20 tower installed on a downstream side of the dust removing part for washing the syngas flowing down through the dust removing part, a slag-cooling water pool installed on a bottom of the gasifier for cooling the fused slag with cooling water fed from outside, and 25 a water feed system for feeding high-temperature water raised in temperature by the fused slag in the slag cooling water pool from the slag-cooling water pool to the downstream side of the gasifier or an upstream side of the dust removing part and cooling the syngas taken 5 out from the gasifier. -- - -- ---- -- - 39 c ~ ~271 11 N2 23 Ai 8 30---- b4 9 N O0 Air 18
Patent AU-2013239981-A1 (AU)
Title: Methods and kits for assessing central nervous system integrity
Inventor: SAMADANI UZMA
IPC: A61B5/0484
Filed: 2013-03-25
Abstract: The invention provides methods and kits for detecting, screening, quantifying orlocalizing the etiology for reduced or impaired cranial nerve function or conduction or associat cranial nucleus or supranuclear input, useful for detecting, diagnosing or screening for increas intracranial pressure, or useful for detecting, diagnosing, monitoring progression of or screenin for a disease or condition featuring increased intracranial pressure by tracking eye movement o the subject. The methods may be performed by a) analyzing eye movement of the subject; b) comparing eye movement of the subject to eye movement of a control or the subject's own baseline eye movement; and c) identifying the subject as having eye movement significantly different from the control or the subject's own baseline eye movement.
Patent AU-2013254945-A1 (AU)
Title: Use of combination preparations, comprising antimycotics
Inventor: NOE MARION
IPC: A61K31/4174
Filed: 2013-11-08
Abstract: Abstract: The invention relates to the use of an antimycotic agent and an epithelial cell or endothelial cell adhesion inhibitor for producing a combination drug for the topical treatment of Can dida mycoses selected from vulvovaginal candidiasis, oropharyn geal candidiasis (oral thrush), diaper dermatitis (diaper thrush) and intertriginous (Candida) eczema.
Patent AU-2013255860-A1 (AU)
Title: Compositions
Inventor: MANDLER MARKUS
IPC: A61K39/00
Filed: 2013-04-30
Abstract: The present invention relates to a composition comprising at least one mimotope of an epitope of alpha-synuclein for use in a method for preventing and/or treating synucleinopathies, wherein said at least one mimotope is coupled or fused to a pharmaceutically acceptable carrier protein selected from the group consisting of a non-toxic diphtheria toxin mutant, keyhole limpet hemocyanin (KLH), diphtheria toxin (DT), tetanus toxid (TT) and Haemophilus influenzae protein D (protein D).
Patent AU-2013262473-A1 (AU)
Title: Methods for improving liver function
Inventor: SEN CHANDAN
IPC: A01N43/16
Filed: 2013-05-20
Abstract: The present invention provides methods to improve liver function utilizing tocotrienols. In particular, various liver pathologies may be treated using the present methods, including cirrhosis, hepatitis, and sclerosing cholangtitis. The present invention also provides methods to increase tissue concentrations of tocotrienols.
Patent AU-2013273343-A1 (AU)
Title: Container sizing method and system
Inventor: BENTERMAN DANIEL
IPC: B31B50/00
Filed: 2013-06-04
Abstract: A carton sizing system (1 ) that has a frame (2), a controller (4), one or more cutters (51 ) movably mounted to the frame (2) and operatively connected to the controller (4), one or more markers (61 ) movably mounted to the frame (2) and operatively connected to the controller (4). The carton sizing system (1 ) also has a measuring means (7) that is operatively connected to the controller (4) and configured to determine, in use, the footprint of an open top carton and to determine the height of one or more objects contained within the carton. The controller (4) is configured to position the one or more cutters (51 ) based on the determined footprint and to cut vertical edges of the carton based on the determined height and also to position the one or more markers (61 ) based on the determined footprint and height and to score or crease vertical walls of the carton between the vertical edges to at least partially define foldable panels.
Patent AU-2013276134-A1 (AU)
Title: Selectively controlling instruction execution in transactional processing
Inventor: GREINER DAN
IPC: G06F9/46
Filed: 2013-06-12
Abstract: Execution of instructions in a transactional environment is selectively controlled. A TRANSACTION BEGIN instruction initiates a transaction and includes controls that selectively indicate whether certain types of instructions are permitted to execute within the transaction. The controls include one or more of an allow access register modification control and an allow floating point operation control.
Patent AU-2013289938-A1 (AU)
Title: Compounds for treatment of spinal muscular atrophy
Inventor: ANDROPHY ELLIOT J
IPC: C07D413/12
Filed: 2013-07-12
Abstract: Disclosed herein are compositions and methods for treatment of spinal muscular atrophy (SMA). In certain embodiments, compounds are provided that increase full-length survival of motor neuron (SMN) protein production by an
Patent AU-2013290132-A1 (AU)
Title: Method for producing C2 oxygenates by fermentation using high oxidation state sulfur
Inventor: TOBEY RICHARD E
IPC: C12P7/06
Filed: 2013-07-11
Abstract: The invention relates to improvements in the production of ethanol and acetate by microbial fermentation, particularly to production of alcohols by microbial fermentation of a substrate comprising CO and the addition of an inorganic sulfur additive. It more particularly relates to the provision of an inorganic organic sulfur source to a fermentation system such that one or more microorganisms convert a substrate comprising CO to ethanol. In one aspect the invention uses a sulfur additive comprising inorganic sulfur compounds having a +2 to a +4 sulfur oxidation state that produces sulfur oxoanions and hydrosulfur oxoanions in an aqueous fermentation medium.
Patent AU-2013305684-A1 (AU)
Title: Oral Dosage Forms of Methyl Hydrogen Fumarate and Prodrugs Thereof
Inventor: WUSTROW DAVID J
IPC: A61K9/16
Filed: 2013-08-22
Abstract: Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also disclosed.
Patent AU-2013322638-A1 (AU)
Title: Prefilled syringe
Inventor: HEINZ JOCHEN
IPC: B65D41/34
Filed: 2013-09-26
Abstract: A prefilled syringe consists of a syringe cylinder (2) which is open at one axial side and is closed by a plunger and which has a Luer lock connection (4) on the other axial side, said lock being molded on an end wall (3) which closes the syringe cylinder (2). The syringe comprises a flowable medium (8) which is filled into the syringe cylinder (2), a soft-elastic stopper (9) which closes at least the Luer (5), and a tamper-evident closure (15) which surrounds the outside of the stopper (9) and which has a predetermined breaking point. The syringe cylinder (2), the end wall (3), and the Luer lock connection (4) are formed as a single piece in the form of a transparent injection-molded plastic part. The tamper-evident closure (15) consists of the same or a similar plastic as the syringe cylinder (2) and is welded to the end wall (3) of the syringe cylinder (2). The welding connection forms the predetermined breaking point, and the stopper (9) is integrated into the tamper-evident closure (15).
Patent AU-2013322868-A1 (AU)
Title: Pulse meter for new-borns
Inventor: EILEVSTJONN JOAR
IPC: A61B5/00
Filed: 2013-09-18
Abstract: Pulse meter comprising a first electrode (4) and second electrode (5), which are adapted to be arranged in contact with a patient body part (9). The first and the second electrode (4, 5) are arranged on a first arm (1) and a second arm (2), respectively. The first and second arm (1, 2) extend out from a central portion (3), and the respective first ends (4a, 5a) of the first and second arm (1, 2) are arranged to be bent away from each other when the pulse meter (10) is being arranged into the applied position on the patient body part (9).
Patent AU-2013340434-A1 (AU)
Title: Ergonomic system for drainage and disposal of bodily fluids
Inventor: CESA JOSEPH A
IPC: A61F5/44
Filed: 2013-10-10
Abstract: There is provided an ergonomic container for draining fluid from the pleural space or peritoneal cavity of a patient. The container is desirably easy to open, easy to pour, easy to hold, easy to control and keep from falling on the floor, and that has graphics that communicate the use and disposal of the container in a relatively simple and easy to understand manner.
Patent AU-2013351909-A1 (AU)
Title: Pipeline system for fluids
Inventor: AUGHTON DAVID JOHN
IPC: G05D7/00
Filed: 2013-11-26
Abstract: The invention provides method and system of controlling flow rate in a pipeline network for fluids. The system includes a demand management system to monitor fluid flow rate in the pipeline network (10) and a pump (34) to increase the fluid flow rate when the demand management system determines an increase in fluid flow rate is required.
Patent AU-2013362909-A1 (AU)
Title: Compositions and methods that utilize a peptide tag that binds to hyaluronan
Inventor: GHOSH JOY
IPC: C12N15/62
Filed: 2013-12-17
Abstract: The invention relates, in part, to compositions and methods that utilize a peptide tag that binds to hyaluronan (HA). The HA tag can be linked to a molecule such as a protein or nucleic acid which, when administered to the eye, results in an increase in ocular half-life and/ or mean residence time, and or a decrease in ocular clearance of the protein or nucleic acid. The invention also encompasses methods for treating ocular disease, including retinal vascular disease, by administering a protein or nucleic acid linked to an HA peptide tag.
Patent AU-2013366544-A1 (AU)
Title: Sealant compositions
Inventor: RODRIGUEZ FERNANDEZ-ALBA JUAN RAMON
IPC: A61L24/10
Filed: 2013-12-20
Abstract: The invention provides a combination comprising thrombin, fibrinogen, and lipidated tissue factor, as well as sealant compositions comprising thereof, and their use as a sealant agent as well as in the treatment of hemorrhages. The combination and compositions of the invention shows improved hemostatic properties and, at the same time, the quality of the clot formed is so consistent that the sealant efficiency is improved over those sealant compositions of the prior art.
Patent WO-2014169344-A1 (WO)
Title: Methods and compositions for the treatment and/or prophylaxis of clostridium difficile associated disease
Inventor: LYRAS DENA
IPC: A61P1/12
Filed: 2014-04-17
Abstract: The present invention relates to methods and compositions for the treatment and/or prophylaxis of Clostridium difficile associated disease (CD AD). In particular, the invention relates to antibodies that bind to C. difficile antigens and are capable of inhibiting C.  difficile  infection, at least one symptom of C.  difficile  associated disease, shedding of C. difficile, and C.  difficile  associated mortality. The compositions of the present application comprise: mammalian or avian antibodies which bind to a C.  difficile  Toxin B; and mammalian or avian antibodies that bind to a C.  difficile  vegetative cell antigen and/or a C.  difficile  endospore antigen.
Patent AU-2014200257-A1 (AU)
Title: An HVAC system configured to obtain demand specific data from a remote unit thereof
Inventor: HREJSA PETE
IPC: F24F11/00
Filed: 2014-01-16
Abstract: An HVAC system (100) that obtains demand specific data from an outdoor unit (144) thereof is provided. An indoor unit controller (150), an outdoor unit controller 5 (148, 200) and an outdoor unit (144) of the HVAC system (100) are also disclosed. In one embodiment, the outdoor unit controller (148, 200) includes: (1) an interface (210) configured to receive a request for a second portion of demand data from an indoor controller (150) of 10 the HVAC system (100), wherein the request includes a first portion of the demand data that corresponds to the second portion and (2) a processor (220) configured to respond to the request by determining the second portion based on the first portion and sending the second portion 15 of the demand data to the indoor controller (150) of the HVAC system (100). HVAC SYSTEM r----------- 1110 CIRCULATION COMFORT 160 FAN(S) SENSOR(S) 12 0 FURNACE(S) IOOROLNIT 150 I ___ __ CONTROLLER I EVAPORATOR I DISPLAY(S) 1 130-fl COIL(S) 148 146 180 1142 CONDENSER DAMPER (ZONE COIL(S) CONTROLLER) 115 140 COMPRESSOR(S) OUTDOOR UNIT 148 CONTROLLER L------------J CONTROL SIGNALS FOR OPERATING OUTDOOR UNIT REQUESTS FOR REPLY WITH NEEDED DEMAND DATA DEMAND DATA 210A INTERFACE 220 PROCESSOR
Patent AU-2014201747-A1 (AU)
Title: A method of treating skin lesions
Inventor: SKOV TORSTEN
IPC: A61P35/00
Filed: 2014-03-24
Abstract: The invention relates to a method of treating skin lesions using ingenol-3-mebutate.
Patent AU-2014202068-A1 (AU)
Title: Vehicle seat, in particular a passenger seat for a bus
Inventor: SCHERELLO MICHAEL
IPC: B60N2/90
Filed: 2014-04-14
Abstract: VEHICLE SEAT, IN PARTICULAR A PASSENGER SEAT FOR A BUS The invention relates to a vehicle seat, in particular a passenger seat for a bus, having a seat member (10) comprising a seat upholstery carrier (11) and seat upholstery (12), which is rigidly arranged on the seat upholstery carrier (11); a backrest (20) comprising a back upholstery carrier (21) and back upholstery (22), which is rigidly arranged on the back upholstery carrier (21); and a support structure for receiving forces which act on the vehicle seat. The support structure is constructed as a rigid carrier frame (30) which is arranged at the peripheral side outside the seat member (10) and the backrest (20) and which is connected to the seat upholstery carrier (11) and the back upholstery carrier (21), and which has carrier rails (31, 32) which are arranged in pairs and which extend along opposing lateral edges (13, 23) of the seat member (10) and the backrest (20). Fig. 1 - 20
Patent AU-2014202228-A1 (AU)
Title: Method and system for dental planning
Inventor: NILSSON URBAN
IPC: G06F19/00
Filed: 2014-04-23
Abstract: A method for computer-based planning of a dental restorative procedure of a patient having a craniooral space and for computer-based planning of a bridge framework for 5 said dental restorative procedure, said method including: determining a first spatial position of a first boundary surface, in said craniooral space, of a veneering of a dental restoration by identifying at least one anatomically fixed reference point that is anatomically 10 stable in a craniooral data set acquired from said patient and then determining from said at least one anatomically fixed referenced point a position in space of at least one of a virtual tooth or an occlusion line, said first boundary surface to be arranged coronally at said occlusion line of 15 said patient; determining a second spatial position of a second boundary surface, in said craniooral space remote said first boundary surface, of a dental implant of said dental restoration, wherein a top surface of said dental implant is 20 said secondary boundary surface; and determining via a computer a third spatial position of at least a portion of said bridge framework relative to at least one of said first and second spatial positions.