baber/WOPTO huggingface dataset:
Patent JP-4326022-B2 (JP)
IPC: A61P43/00
Filed: 1996-06-03
Granted: 2009-09-02
Abstract: A metalloprotease that converts TNF- alpha  from the 26kD cell form to the cell form to the 17 kD form has been isolated and purified and the cDNA sequence known. In particular, the protease has a molecular weight of approximately 80 kD. The isolated and purified protease is useful for designing an inhibitor thereof, and may find use as a therapeutic agent. Assays for detecting the protease-inhibiting activity of a molecule are also an aspect of the invention.
Patent JP-3078329-B2 (JP)
IPC: H04B17/00
Filed: 1995-07-13
Granted: 2000-08-21
Abstract: A method and apparatus for simulating signal interference in one communication channel within a communication system, such as cellular or wireless subscriber telephone and/or data systems. The communication system may be of a cellular type in which users from a plurality of cells communicate information signals between one another using at least one base station and code division multiple access (CDMA) spread spectrum type communication signals. The base station is included in a first of the cells and has a transmitter from which information is transmitted to subscriber units over at least one communication channel. The disclosed method includes the step of determining a first composite signal energy associated with signal transmission from the base station transmitter over a first set of simulated communication channels. The simulation method further contemplates estimating a first average data rate for the first composite signal energy. Signal power transmitted over the one communication channel is adjusted in accordance with a first interference signal which is based on the first composite signal energy and first average data rate. In a preferred implementation, a determination is also made of a second composite signal energy associated with signal transmissions from base station transmitters in other cells over a second set of simulated communication channels. An estimate is also made of a second average data rate for the second composite signal energy to enable generation of a second interference signal.
Patent JP-3118253-B2 (JP)
IPC: A61K41/00
Filed: 1990-03-29
Granted: 2000-12-18
Abstract: Compounds of fomula (1) or formula (2):   <IMAGE> (1)  <IMAGE> (2) wherein M is a non-paramagnetic metal selected from Mg+2, and Zn+2, or represents 2 H+ each H+ bonded to one of the N atoms connected by the solid lines; R1 is a saturated or unsaturated hydrocarbyl residue of 8-25C; each R2 is independently selected from the group consisting of vinyl, ethyl, acetyl and 1-hydroxyethyl, and X is COOR3, wherein R3 is alkyl (1-4C); are useful in photodynamic therapy and diagnosis. These compounds photosensitize target biological substrates to irradiation, and treating said substrates with these sensitizers followed by irradiation leads to the impairment or destruction of the biological substrate. When administered systemically, these compounds accumulate in the undesired target biological substrate. The compounds can also be utilized in vitro, for example to destroy infectious cells or viruses in blood intended for transfusion.
Patent JP-3518547-B2 (JP)
IPC: C07K14/46
Filed: 1991-04-04
Granted: 2004-04-12
Abstract: Cyclosporin A, or another compound having cyclosporin A-like activity, and cobra venom factor, or another complement inhibitor, can be used in conjunction with each other to promote allograft and concordant xenograft survival and to rescue such grafts from rejection.
Patent JP-3778926-B2 (JP)
IPC: C07D295/125
Filed: 1994-08-12
Granted: 2006-05-24
Abstract: A remedy for nervous diseases caused by peripheral or central nervous disorder containing a 2-acylaminopropanol derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof as the active ingredient, wherein R<1> represents alkyl, or phenyl or cyclohexyl both of which may be substituted by one to three same or different substituents selected from the group consisting of alkyl, alkoxy, hydroxy and nitro. It can be used for treating various central and peripheral nervous diseases by inducing biosynthesis of endogenous glycosphingolipids, especially a ganglioside, to thereby accelerate axon extension and synapse formation. <CHEM>
Patent JP-2828775-B2 (JP)
IPC: C07C19/12
Filed: 1991-06-04
Granted: 1998-11-25
Abstract: PCT No. PCT/BE91/00034 Sec. 371 Date Dec. 8, 1992 Sec. 102(e) Date Dec. 8, 1992 PCT Filed Jun. 4, 1991 PCT Pub. No. WO91/18852 PCT Pub. Date Dec. 12, 1991.The invention relates to a thermal process the production of 1,1-dichloro-1-fluoroethane by hydrofluorination of vinylidene chloride carried out in the absence of any catalyst.
Patent JP-3102887-B2 (JP)
IPC: C11D1/29
Filed: 1994-10-28
Granted: 2000-10-23
Abstract: The present invention encompasses a personal cleansing bar comprising from 10 parts to 70 parts by bar weight of sodium cocoyl isethionate (SCI), 4.5 parts to 50 parts magnesium soap and 4 parts to 15 parts liquid polyol, wherein said polyol has at least two alcohol groups attached to separate carbon atoms in the chain, and must be water soluble and liquid at room temperature. The bars of this invention are mild, lather better, and are easier to make than corresponding bars without liquid polyol.
Patent JP-3455853-B2 (JP)
IPC: F16K31/363
Filed: 1994-11-10
Granted: 2003-10-14
Abstract: PCT No. PCT/FR94/01318 Sec. 371 Date Jul. 17, 1996 Sec. 102(e) Date Jul. 17, 1996 PCT Filed Nov. 10, 1994 PCT Pub. No. WO95/13973 PCT Pub. Date May 26, 1995A dispensing device (1) for supplying a gaseous fluid (3) to a space (2) and abruptly emptying said space (2) to deliver its contents to an apparatus (4) once the supply has been cut off. The device (1) is characterized in that to reduce the fluid pressure in a supply chamber of the device and cause a sealing member to open abruptly once the supply of pressurized fluid (3) to the device (1) has been cut off, rather than discharging the pressurized fluid (3) in the supply chamber (5) to the atmosphere and that part of the supply circuit between said chamber (5) and the cut-off assembly, the pressurized fluid (3) which previously held the sealing member against a seal seat (10) is released into a discharge duct in the device.
Patent JP-4190579-B2 (JP)
IPC: C12N15/09
Filed: 1996-09-26
Granted: 2008-12-03
Abstract: A recombinant retrovirus capable of infecting a non-dividing cell and a method of producing such a virus is provided. The recombinant retrovirus is preferably of lentivirus origin and is useful for the treatment of a variety of disorders including neurological disorders and disorders of other non-dividing cells.
Patent JP-3141205-B2 (JP)
IPC: G01T1/20
Filed: 1991-08-21
Granted: 2001-03-05
Abstract: PCT No. PCT/FR91/00680 Sec. 371 Date Apr. 16, 1993 Sec. 102(e) Date Apr. 16, 1993 PCT Filed Aug. 21, 1991 PCT Pub. No. WO92/03836 PCT Pub. Date Mar. 5, 1992.The present invention relates to a low level, high resolution imager of the type comprising a light-amplifier tube (300) including a photocathode (310), at least one microchannel slab (330) serving as an electron amplifier, and a light-emitting phosphor screen (340) provided with a metal layer (342), an electron camera (400) comprising a photosensitive matrix array (410) suitable for transforming a received photon into an electron, and control means (700) for the electron camera, characterized by the fact that the control means (700) comprise an amplifier (710) responsive to the electrons collected on the metal layer (342) of the light-emitting phosphor screen (340) to control integration cycles of the photosensitive matrix array (410) in repetitive one-shot mode synchronized on the appearance of photons at the input of the light-amplifying tube (300).
Patent JP-3739098-B2 (JP)
IPC: A61K47/12
Filed: 1997-09-10
Granted: 2006-01-25
Abstract: There are disclosed compositions for theraputic use comprising a mixture of from 1:1 (w:w) to 10:1 (w:w) of a nonionic surfactant and an active ingredient in a pharmaceutically acceptable diluent or carrier, wherein the nonionic surfactant is a deoxycholate and wherein the active ingredient is selected from the group consisting of stearyl alcohol, erucyl alcohol, brassidyl alcohol, n-docosanol, arachidyl alcohol, n-docosane, n-docosanoic acid erucamide, stearic acid, or mixtures thereof. <IMAGE>
Patent JP-3192147-B2 (JP)
IPC: A61B19/08
Filed: 1993-04-05
Granted: 2001-07-23
Abstract: A suture passer is provided comprising an elongate tubular probe guide (125) extending in a distal direction from a handle (110). An elongate pointed probe (115) is disposed to be axially movable within the tubular probe guide (125). A recess (160) is provided on the probe (115) and an opening (130) is provided on the tubular probe guide (125) for receiving a suture. The probe (115) may be moved axially with respect to the probe guide (125) such that the recess (160) aligns with the opening (130) for receiving the suture. In a second position, the recess (160) is moved out of alignment with the opening (130) to trap the suture within the recess.
Patent JP-3547454-B2 (JP)
IPC: C12Q1/68
Filed: 1997-10-20
Granted: 2004-07-28
Abstract: An optical assay device for the detection of an analyte of interest in a sample comprising a support containing channels, an optically functional layer positioned on the support such that the optically functional layer and the support allow for laminar flow of the sample through layers of the device, an attachment layer positioned on the optically functional layer, and an analyte specific receptive layer positioned on the attachment layer.
Patent JP-2735387-B2 (JP)
IPC: G01L17/00
Filed: 1994-03-29
Granted: 1998-04-02
Abstract: PCT No. PCT/JP94/00501 Sec. 371 Date Nov. 16, 1994 Sec. 102(e) Date Nov. 16, 1994 PCT Filed Mar. 29, 1994 PCT Pub. No. WO94/22681 PCT Pub. Date Oct. 13, 1994A method and device for detecting a deflated tire on a vehicle by comparing the rolling radii of the tires by means of comparing angular velocity speed signals from wheel speed sensors, one at each wheel, characterized by calculating an error value DEL', where   <IMAGE>   wherein C1, C2, C3 and C4 are angular velocity values for left-hand front, right=hand front, left-hand rear and right-hand rear wheels of the vehicle respectively, determining a correction factor LAT, calculating a corrected error value DEL where DEL=DEL'-DELCOR wherein DELCOR=(LATxA)+(BxLAT2) wherein A and B are vehicle related constants, and operating a tire warning indicator provided in the vehicle to indicate that at least one tire is deflated when it is sensed that the magnitude of the corrected error value DEL is in the range 0.05 to 0.5.
Patent JP-3564609-B2 (JP)
IPC: H04H60/31
Filed: 1994-04-14
Granted: 2004-09-15
Abstract: PCT No. PCT/EP94/01161 PCT Filed Apr. 14, 1994 PCT Pub. No. WO94/24785 PCT Pub. Date Oct. 27, 1994A device for storing picture information displayed on a television screen consists of a storage medium made of a photosensitive material which may be secured to the surface of the screen by an active adhesive layer on the screen.
Patent JP-3138278-B2 (JP)
IPC: G01N15/02
Filed: 1995-04-21
Granted: 2001-02-26
Abstract: PCT No. PCT/EP95/01521 Sec. 371 Date Jan. 13, 1997 Sec. 102(e) Date Jan. 13, 1997 PCT Filed Apr. 21, 1995 PCT Pub. No. WO95/29393 PCT Pub. Date Nov. 2, 1995A device is disclosed for measuring light scatter by particles (3) suspended in a carrier medium with a view to ascertaining the density, size or size distribution of the particles. The device comprises: at least one light source (8) which directs light onto a light-scattering center (2) in the carrier medium with the suspended particles (3); a receiver (4) to pick up a portion of the scattered light from the light-scattering center; and an evaluating device connected downstream of the receiver (4). The invention provides for an elongated detection chamber bounded radially around its central axis by the wall of a housing (1) which also acts as a duct for the through-flowing carrier medium with the suspended particles (3). Each light source (8) is mounted on the wall of the housing (1) and points toward the central axis of the detection chamber. The receiver is coaxial with the detection chamber and includes a sensor and a diaphragm system (6, 7) which is designed in such a way that the wall of the housing (1) surrounding the light scattering center (2) is excluded from the field of view of the sensor.
Patent JP-3570726-B2 (JP)
IPC: A61M60/857
Filed: 1997-04-02
Granted: 2004-09-29
Abstract: A blood pump having a motor housing and a pump housing which are rigidly connected to one another in an axially spaced relationship. Both housings are of substantially the same diameter and are sized to enable the pump to be introduced via catheter through the body's blood-vessel system. The impeller is mounted in the pump housing on a longitudinally and radially acting bearing designed as a point-support bearing. To avoid oscillation of the impeller, it is fitted with an alignment device which may have a hydrodynamic or mechanical action. Rotation of the motor is transferred to the impeller via a magnetic coupling.
Patent JP-4420472-B2 (JP)
IPC: A61K47/48
Filed: 1997-04-15
Granted: 2010-02-24
Abstract: Disclosed is a drug complex of a drug having a hydroxyl group, which is capable of controlling the rate of the release of the drug therefrom in blood, the drug complex being represented by the following formula (1): <CHEM> wherein A represents at least one carrier selected from the group consisting of saccharides each having a carboxyl group, polyethylene glycols each having a carboxyl group, aliphatic carboxylic acids each having a carboxyl group, and derivatives thereof each having a carboxyl group; B represents at least one spacer comprised of a compound having a amino group and a carboxyl group; C represents at least one drug having a hydroxyl group, wherein the carrier A is bonded to the spacer B through an amide bond formed between the carboxyl group of the carrier A and the amino group of the spacer B; and the spacer B is bonded to the drug C through an ester bond formed between the carboxyl group of the spacer B and the hydroxyl group of the drug C. The drug complex of the present invention is capable of not only surely controlling the rate of release of the drug therefrom, but also enhancing the transferability of the drug to target tissues and the pharmacological effect of the drug.
Patent JP-4164128-B2 (JP)
IPC: C12Q1/68
Filed: 1998-01-07
Granted: 2008-10-08
Abstract: The present invention provides a method of screening individuals at risk for developing diseases caused by trinucleotide repeat sequence instability. Specifically, the present invention is drawn to screening individuals at risk for developing autosomal dominant spinocerebellar ataxia type 6 by determining the length of a CAG trinucleotide repeat in the alpha<SUB>1A </SUB>calcium channel gene of the individual. In addition, there is provided a method of identifying genes which are disease-causing due to trinucleotide repeat sequence instability by large scale genotyping.
Patent JP-4766723-B2 (JP)
IPC: B29C67/00
Filed: 1998-04-28
Granted: 2011-09-07
Abstract: Solid objects are formed in an imagewise layering process in which components of a dispersion are homogenized to form an alloy. Imagewise exposure of the layers to radiation to form an alloy permits separation of the exposed, homogenized regions from non-exposed, non-homogenized regions. As each layer is formed and imagewise homogenized, contiguous layer regions are bonded together to form a homogenized, three-dimensional object which may be separated from surrounding dispersion.
Patent JP-4172727-B2 (JP)
IPC: H04B1/59
Filed: 1998-05-14
Granted: 2008-10-29
Abstract: A method and an identification system for communicating between a reader (10) and a plurality of transponders (1,2,3) are disclosed. The reader (10) has a transmitter (11) for transmitting a signal and each transponder (1,2,3) includes a receiver for receiving the reader signal and a transmitter for generating a transponder signal. When the reader (10) recognises a transponder signal from one of the transponders (1) it immediately issues a mute instruction, muting all other active transponders (2,3) and passing control to the said transponder (1), without the need for a specifically timed acknowledgement to the said controlling transponder (1). The reader (10) may issue a single disable/wakeup instruction which disables the controlling transponder (1) returning control to the reader (10) and reactivated all muted (but not disabled) transponders.(2,3).
Patent MD-3613-B2 (MD)
Title: Method and reactor for non-thermal decomposition and pasteurization of organic materials by electroporation
Inventor: SCHULTHEISS CHRISTOPH
IPC: A23L13/70
Filed: 2002-08-21
Abstract: In a reaction chamber, which constitutes a component of a process installation for obtaining foodstuffs or foodstuff components, biological products in harvested form that are whole or in pieces are subjected to pulsed electric fields as they pass through said reaction chamber, said electric fields forming pores in the cell walls so as to irreversibly open the latter, thus making the content of the cells more easily accessible. This is achieved by electrode groups, which can be energized to a high voltage and are located in the wall of a longitudinal passage of the reactor through which the process material is moved past grounded electrodes located in an opposing longitudinal wall area. Each electrode group is connected to an electric energy accumulator such as for example, a Marx generator, by means of a switch, in order to rapidly establish electric fields of multiple directions between the charged and the grounded electrodes.
Patent ES-2327023-B2 (ES)
Title: Metodo para la deteccion y cuantificacion selectiva de acido domoico mediante sus efectos toxicos sobre celulas excitables.
Inventor: PEREZ GOMEZ ANABEL
IPC: C12N5/07
Filed: 2009-05-13
Granted: 2010-06-09
Abstract: Método para la detección y cuantificación
selectiva de ácido domoico mediante  sus efectos tóxicos sobre
células excitables. La presente invención se  refiere a un método
para la detección y cuantificación sistemática de la  presencia de
ácido domoico (DOM) en muestras problema, como extractos de 
alimentos marinos o muestras de aguas, mediante la utilización de
células  excitables en un medio extracelular con el ión sodio total
o parcialmente  sustituido. La exposición de los cultivos de células
excitables a DOM en  un medio como el mencionado, da lugar a una
disminución de la viabilidad  celular superior a la observada en
presencia de ión sodio, mientras que  el pretratamiento con un
inhibidor de los receptores activados por DOM  inhibidor dicho
efecto tóxico. Con este método, es posible determinar la  presencia
de concentraciones de DOM en la muestra problema que no serian 
detectables en presencia de ión sodio en el medio extracelular.
Patent ES-2350435-B2 (ES)
Inventor: GIL BRAVO ANTONIO
IPC: B01J20/08
Filed: 2010-06-23
Granted: 2011-06-13
Abstract: Modification of saline slags from the processes of second smelting of aluminium and the use thereof as adsorbents of the products obtained. The activation is described of saline slags from the processes of second smelting of aluminium through contact with acid, basic, or neutral aqueous solutions, separation of the aqueous solution and calcinations at high temperatures. The procedure of the invention permits the obtainment of materials having high specific surface area, even exceeding 200 m2, in particular when the slag is placed in contact with water under reflux conditions. The activated slags obtained may be utilized as adsorbents of heavy metals present in aqueous solutions. Having been utilized, they may be regenerated by means of treatment with acid solutions, washing and drying, and be reutilized.
Patent ES-2578997-B2 (ES)
Title: Grafeno covalentemente modificado
Inventor: CALLEJA MITJA FABIÁN
IPC: H01L31/028
Filed: 2015-02-02
Granted: 2017-01-27
Abstract: Grafeno covalentemente modificaco.#La presente invención está dirigida a un sistema en el que las propiedades electrónicas del grafeno pueden ser modificadas de forma controlada. En dicho sistema, el grafeno es químicamente funcionalizado con moléculas alquílicas que se unen covalentemente a los átomos de carbonos del grafeno. El grado de recubrimiento de la capa del grafeno de la presente invención permite regular la apertura de la banda de energía prohibida en el diagrama de bandas de energía del grafeno.
Patent AU-2001252149-B2 (AU)
Title: Bi-axially oriented and heat-set multilayer thermoplastic film for packaging
Inventor: CESARE GREGORIO DI
IPC: B29C47/06
Filed: 2001-02-27
Granted: 2005-07-14
Abstract: A multi-layer, thermoplastic film bi-axially oriented at a stretching ratio >= to about 3.0:1 in the machine direction and at a stretching ratio >= about 6.0:1 in the transverse direction, which film comprises a layer a) comprising at least 50 wt. % of a crystalline or partially crystalline co-polyamide characterized by a T<SUB>g</SUB><=100° C. and at least one outer heat-sealing layer b) comprising a polyolefin, said film being further characterized in that it has a % free shrink at 100° C.<=3 in each direction.
Patent AU-2001260362-B2 (AU)
Title: A drag reducing composition
Inventor: KARHU ESA
IPC: C08L91/00
Filed: 2001-05-14
Granted: 2005-07-14
Abstract: The invention relates to a concentrated, non-agglomerating, soluble and compatible drag reducing agent composition. It contains (a) from 1 to 60% of a polymer, e.g. non-crystalline and ultrahigh molecular weight poly-alpha-olefin, capable of reducing drag, and (b) from 40 to 99% of a natural fat or oil, e.g. linseed or rapeseed oil, based on the comined weight of (a) and (b). Preferably, it also contains (c) from 0.1 to 50% of a dispersion stabilising agent, e.g. a fatty acid soap, based on the combined weight of (a), (b) and (c).
Patent AU-2001285152-B2 (AU)
Title: Functionalized polymeric media for separation of analytes
Inventor: BOUIS PAUL A
IPC: C08F257/00
Filed: 2001-08-21
Granted: 2005-11-17
Abstract: Separation of a variety of analytes that are polar, nonpolar and ionic using functionalized polymeric media is disclosed. Preformed rigid particles of highly crosslinked homopolymer of polyvinylidene compounds are functionalize using the residual vinyl groups onto which monovinyl compounds are covalently bonded through polymerization. The functionalization imparts desirable surface properties for separation applications such as liquid chromatography and solid phase extraction.
Patent AU-2002231281-B2 (AU)
Title: Surface transfection and expression procedure
Inventor: UHLER MICHAEL D
IPC: C12M1/00
Filed: 2001-11-02
Granted: 2008-02-07
Abstract: The present invention relates to a method of transfecting cells comprising applying cells directly onto nucleic acids which are immobilized in transfection complexes on a surface and which transfect the cells. Preferably, the nucleic acids are immobilized in an array. In another aspect of the present invention, the method further includes expression of the nucleic acids in the transfected cells. In yet another aspect of the present invention, the method further comprises detecting the expression of the nucleic acids in the transfected cells.
Patent AU-2002255114-B2 (AU)
Title: An induction regulator for an internal combustion engine
Inventor: KENNEDY ROGER
IPC: F02M31/135
Filed: 2002-04-19
Granted: 2007-03-29
Abstract: The present invention concerns an induction regulator (101) for an internal combustion engine comprising at least one perforated element (103) for allowing the passage of fuel/air mixture therethrough, a propeller connected to a power supply for driving the propeller, and means for mounting the at least one perforated element (103) and the propeller beneath the perforated element (103) in the inlet manifold of an engine.