baber/WOPTO huggingface dataset:
Patent CA-2560822-A1 (CA)
Title: Geldanamycin and derivatives inhibit cancer invasion and identify novel targets
Inventor: VANDE WOUDE GEORGE F
IPC: C07D225/06
Filed: 2005-03-28
Abstract: Geldanamycin derivatives that block the uPA-plasmin network and inhibit growth and invasion by glioblastoma cells and other tumors at femtomolar concentrations are potentially highly active anti-cancer drugs. GA and various 17-amino-17-demethoxygelddanamycin derivatives are disclosed that block HGF/SF-mediated Met tyrosine kinase receptor-dependent uPA activation at fM levels.  Other ansamycins (macbecins I and II), GA derivatives, and radicicol required concentrations several logs higher (>=nM) to achieve such inhibition. The inhibitory activity of tested compounds was discordant with the known ability of drugs of this class to bind to hsp90, indicating the existence of a novel target(s) for HGF/SF -mediated events in tumor development. Methods of using such compounds to inhibit cancer cell activities and to treat tumors are disclosed. Such treatment with low doses of these highly active compounds provide an option for treating various Met-expressing tumors, in particular invasive brain cancers, either alone or in combination with conventional surgery, chemotherapy, or radiotherapy.
Patent CA-2561823-A1 (CA)
Inventor: FANSLOW WILLIAM C III
IPC: C07K16/30
Filed: 2005-04-22
Abstract: Anti-CD148 antibodies and antigen-binding regions thereof, as well as pharmaceutical compositions comprising such antibodies and antigen-binding regions, are described. Also described are methods of using such antibodies and antigen-binding regions to bind CD148 epitopes and activate CD148 function, such as inhibition of angiogenesis. Epitopes that can be used to activate CD148 function and anti-angiogenesis activity are also described, as well as methods of identifying compounds that can bind them.
Patent CA-2563482-A1 (CA)
Inventor: ORLANDO ROBERT JOSEPH
IPC: F02C3/067
Filed: 2006-10-12
Abstract: A method for assembling a gas turbine engine (10) includes providing a core gas turbine engine (12) including a high-pressure compressor (26), a combustor (28), and a turbine (30), and coupling a counter-rotating fan assembly (16) to the core gas turbine engine such that air discharged from the counter-rotating fan assembly is channeled directly into an inlet (104) of the gas turbine engine compressor.
Patent CA-2565677-A1 (CA)
Title: Method and apparatus for mass selective axial ejection
Inventor: LONDRY FRANCK
IPC: H01J49/00
Filed: 2005-05-05
Abstract: A mass spectrometer system and a method of operating a mass spectrometer having an elongated rod set, the rod set having an entrance end, an exit end, a plurality of rods and a longitudinal axis, involving (a) admitting ions into the entrance end of the rod set; (b) producing an RF field between the plurality of rods to radially confine the ions in the rod set; (c) providing a static axial electric field within the rod set; and (d) separating the ions into a first group of ions and a second group of ions by providing an oscillating axial electric field within the rod set to counteract the static axial electric field, wherein the oscillating axial electric field varies along the longitudinal axis of the rod set.
Patent CA-2569023-A1 (CA)
Title: Thin printable flexible electrochemical cell and method of making the same
Inventor: TUCHOLSKI GARY R
IPC: H01M10/04
Filed: 2005-04-21
Abstract: A thin printed flexible electrochemical cell with a high moisture and oxygen barrier polymer film sealed and folded package featuring a printed cathode deposited on a highly conductive carbon printed cathode collector with a zinc foil anode or printed anode placed adjacent to the cathode. After the cell components are added to the special laminated polymer substrate, the web is processed automatically on a modified high-speed commercial horizontal pouch filling machine to complete the cell assembly process. In this process a starch coated paper separator layer may be inserted over the anode and the cathode, and then the aqueous electrolyte solution is added to the cell. To complete the process, all four edges of the cell are heat sealed to confine the cell components within the cell cavity and each cell is trimmed off the continuous web.
Patent CA-2569592-A1 (CA)
Title: Heterocyclic carboxamides with microbiocidal activity
Inventor: CORSI CAMILLA
IPC: C07D231/40
Filed: 2005-06-21
Abstract: Compounds of the formula (I), in which the substituents are as defined in claim 1 are suitable for use as microbiocides.
Patent CA-2569640-A1 (CA)
Inventor: WANG NUI
IPC: F16D65/18
Filed: 2005-06-15
Abstract: An actuating mechanism, particularly for a disc brake caliper, including a screw actuator having a screw (40) and a nut (18) threadably coupled together, an electric drive for driving one of the screw (40) and the nut (18) axially relative to the other and including a stator (20) and a rotor (22), a sleeve assembly including a generally cylindrical sleeve (25) interposed between the rotor (22) and the nut (18) and supporting the rotor (22) for rotation relative to the sleeve (25). The rotor (22) is connected to one of the screw (40) or the nut (18) for rotating the screw (40) or the nut (18). The screw actuator being at least partly mounted within the sleeve (25) and being arranged to bear against a portion of the sleeve assembly to transmit axial thrust to the sleeve assembly, and the sleeve assembly cooperating with an abutment to transmit the axial thrust to the abutment.
Patent CA-2570101-A1 (CA)
Inventor: VOGT M FRANZ
IPC: C25B11/12
Filed: 2005-05-23
Abstract: La présente invention concerne un procédé pour fabriquer une électrode de carbone destinée à s'utiliser en tant qu'anode dans une cellule de réduction d'aluminium; il consiste à mélanger un agrégat qui comprend un mélange de coke particulaire non compacté et un matériau particulaire carboné autre que le coke non compacté, avec du brai de houille ou de pétrole ou d'une combinaison de ces brais à une température élevée pour former une pâte, ledit agrégat comprenant une combinaison de particules grossières, moyennes et fines, ledit coke particulaire non compacté pouvant comprendre une majorité desdites particules fines. La pâte comprend entre environ 80 et environ 90 %, en poids, dudit agrégat, et entre environ 10 et environ 20 %, en poids, dudit brai. Selon le procédé, on forme ladite pâte en un corps solide, et l'on cuit ce corps solide à une température élevée pour former ladite électrode de carbone.
Patent CA-2573946-A1 (CA)
Title: Aqueous liquid bleach compositions
Inventor: JONES MARTIN VINCENT
IPC: C11D3/395
Filed: 2005-06-23
Abstract: The invention provides a method for providing lasting antimicrobial activity on a hard surface as well as an aqueous liquid bleaching composition suitable for use in that method. The method comprises treating a hard surface with a composition comprises a hypochlorite salt and an N-chloro compound chosen from N-chloro-arylsulphonamides and N-chloro-imidodisulphate salt, the composition having pH above 7.
Patent CA-2575974-A1 (CA)
Inventor: KATES LAWRENCE
IPC: F25B49/02
Filed: 2005-06-27
Abstract: A real-time monitoring system that monitors various aspects of the operation of a refrigerant-cycle system is described. In one embodiment, the system includes a processor that measures power provided to the refrigerant-cycle system and that gathers data from one or more sensors and uses the sensor data to calculate a figure of merit related to the efficiency of the system. In one embodiment, the sensors include one or more of the following sensors: a suction line temperature sensor, a suction line pressure sensor, a suction line flow sensor, a hot gas line temperature sensor, a hot gas line pressure sensor, a hot gas line flow sensor, a liquid line temperature sensor, a liquid line pressure sensor, a liquid line flow sensor. In one embodiment, the sensors include one or more of an evaporator air temperature input sensor, an evaporator air temperature output sensor, an evaporator airflow sensor, an evaporator air humidity sensor, and a differential pressure sensor. In one embodiment, the sensors include one or more of a condenser air temperature input sensor, a condenser air temperature output sensor, and a condenser air flow sensor, an evaporator air humidity sensor. In one embodiment, the sensors include one or more of an ambient air sensor and an ambient humidity sensor.
Patent CA-2577186-A1 (CA)
Title: Detection a base de diamant synthetique
Inventor: TROMSON DOMINIQUE
IPC: G01T1/26
Filed: 2005-09-01
Abstract: L'invention concerne un détecteur comportant une plaque (2) détectrice formée d'une plaque mince de diamant synthétique, caractérisé en ce qu'il comporte des moyens (11, 4) de chauffage de la plaque détectrice, lesdits moyens de chauffage comportant une plaque (4) mince de chauffage dont le matériau est constitué essentiellement d'atomes de carbone. L'invention concerne également un dispositif comportant un tel détecteur et un procédé de mesure utilisant un tel détecteur et un procédé de fabrication d'un tel détecteur.
Patent CA-2577581-A1 (CA)
Title: Methods and apparatus for measuring flow velocity in a wellbore using nmr and applications using same
Inventor: SPEIER PETER
IPC: E21B47/06
Filed: 2002-09-09
Abstract: The present invention provides methods and apparatus for determining flow velocity within a formation utilizing nuclear magnetic resonance (NMR) techniques in which the shape of the resonance region is restricted so that sensitivity to radial flow or vertical flow is obtained (or both when more than one NMR tool is used). Flow velocity using these NMR tools is determined using decay amplitude, frequency displacement or stimulated echoes (where the spins are stored along the magnetic field instead of the transverse plane to exploit echo decays and frequency displacements) based on the application of adiabatic pulses. Based on the described NMR measurement of flow velocity, additional wellbore parameters may be obtained such as a direct measurement of permeability, an assessment of drilling damage to the wellbore, formation pressure, invasion rate of the mud filtrate or the migration of fine mud particles during sampling operations.
Patent CA-2577963-A1 (CA)
Inventor: GARDINER PAUL T
IPC: A61K9/68
Filed: 2005-08-24
Abstract: A method for activating the protein synthesis machinery and deactivating catabolic processes within skeletal muscle by regulating molecular signals to control anabolic and anti-catabolic activity in skeletal muscle via nutrients including but not limited to amino acids and growth factors. Also provided is a supplemental dietary composition that may include L-Leucine, including salts or derivatives thereof, L-phenylalanine, including salts or derivatives thereof, and/or creatine, including salts or derivatives thereof, and may also include sources of dietary protein and/or carbohydrates.
Patent CA-2578408-A1 (CA)
Inventor: JACQUET-FRANCILLON PIERRE
IPC: F02C9/48
Filed: 2005-09-12
Abstract: The invention concerns a device for protection against icing for aircraft engines comprising at least one sensor (1), sensitive to an amount of accumulated ice, arranged in the air intake of an aircraft engine (2), a system for measuring (3) said amount and comparing (4) said amount to a predetermined threshold (S) and a triggering system (5) for launching a response to the detection of the crossing of the predetermined threshold, the response may be an alarm, an increase in the engine power delayed by the engine control system (7) or the return of hot air upstream of the engine.
Patent CA-2578828-A1 (CA)
Title: Torque transmitting coupling
Inventor: PISONI ATTILIO C
IPC: E21B7/04
Filed: 2002-04-26
Abstract: The invention refers to a rotary steerable drilling tool having a tool collar and a bit shaft. The bit shaft is supported within the tool collar for pivotal movement about a fixed position along the bit shaft. Moreover, the rotary steerable drilling tool includes a variable bit shaft angulating mechanism, located within the interior of the tool collar. The variable bit shaft angulating mechanism includes a motor, an offset mandrel, and a variable offset coupling. The motor is attached to the upper end of the offset mandrel and adapted to rotate the offset mandrel.  The upper end of the variable offset coupling is uncoupleably attached to an offset location of the lower end of the offset mandrel, and the upper end of the bit shaft is rotatably coupled to the variable offset coupling. The rotary steerable drilling tool also includes a torque transmitting coupling adapted to transmit torque from the tool collar to the bit shaft at the fixed position along the bit shaft.  Finally, a seal system is adapted to seal between the lower end of the tool collar and the bit shaft.
Patent CA-2578976-A1 (CA)
Inventor: SHIBASAKI FUMIO
IPC: H04L12/66
Filed: 2007-02-19
Abstract: According to one embodiment, a gateway apparatus includes a pool which retains the plurality of media gateway channel resources in each of a plurality of resource groups constituted by dividing the plurality of media gateway channel resources in accordance with necessity levels thereof, a memory which stores a group table indicating the correspondence/relation between the plurality of resource groups and the communication terminals belonging to these resource groups, and a controller which refers to the group table when an arbitrary communication terminal among the plurality of communication terminals requests to use the media gateway channel resource and which reads from the pool an idle media gateway channel resource in the corresponding resource group for the arbitrary communication terminal based on the result of the reference to allocate the idle media gateway channel resource to the arbitrary communication terminal.
Patent CA-2579131-A1 (CA)
Inventor: STANLEY ANNE
IPC: C07K14/59
Filed: 2005-11-08
Abstract: The invention relates to a method for purifying recombinant human FSH or an FSH variant starting from crude FSH, comprising the following steps: 1) dye-affinity chromatography; 2) hydrophobic interaction chromatography; and 3) reverse phase chromatography.
Patent CA-2579247-A1 (CA)
Inventor: KRAEMER KLAUS
IPC: B67C7/00
Filed: 2007-02-21
Abstract: A beverage bottling plant for filling bottles with a liquid beverage filling material having an information adding station.
Patent CA-2581846-A1 (CA)
Title: High yielding soybean plants with low linolenic acid
Inventor: REITER ROBERT
IPC: A23L11/00
Filed: 2005-09-29
Abstract: The invention overcomes the deficiencies of the prior art by providing methods for marker assisted selection to create plants of a soybean variety that exhibit a mid/low linolenic acid content with a commercially significant yield and an agronomically elite phenotype. The invention also provides derivatives and plant parts of these plants. Further provided by the invention are methods for the use of these plants. The invention is significant in that oil with decreased linolenic acid exhibits numerous beneficial characteristics yet prior art varieties with decreased linolenic acid also exhibited decreased yield and poor agronomic quality.
Patent CA-2582830-A1 (CA)
Title: High efficiency balanced detection interferometer
Inventor: HACKER MARTIN
IPC: G01B9/02
Filed: 2005-11-10
Abstract: An interferometer configured for use in optical coherence domain (OCT) reflectometry systems is disclosed. In the preferred embodiments, efficient routing of light and a balanced detection arrangement provide a high signal to noise ratio. In a first set of embodiments, a 3x3 coupler is used to split light along separate sample and reference paths and also for combining light returning from those paths and supplying the interfered collected light to the detection system. In an alternate set of embodiments, a pair of cascaded 2x2 couplers provides a similar function. The interferometer can be used with various OCT modalities including time-domain and frequency domain approaches.
Patent CA-2585651-A1 (CA)
Title: Lock box
Inventor: HANDEL MARK VAN
IPC: B65D55/14
Filed: 2005-11-01
Abstract: A lock box that includes a body for storing keys, a lid, and a latching mechanism. The lid is arranged for selectively covering the opening. The body and the lid include securing apertures that are cooperatively positioned when the lid covers the opening. The body and lid also include cutouts that are aligned when the lid covers the opening. The latching mechanism is slideably coupled to the lid and includes a cantilever spring and a tab. The tab passes through the cutouts in the body and lid when the lid covers the opening and the latching mechanism is in a latched position. The cantilever spring is partially located in an aperture in the lid. The position of the cantilever spring is determined by whether the latching mechanism is latched or unlatched. The lock box when secured can require the cooperation of multiple users to open.
Patent CA-2588737-A1 (CA)
Title: Injection molding machine apparatus and method with moving platen injection and ejection actuation
Inventor: KEIR WILLIAM STEVEN
IPC: B29C45/40
Filed: 2005-11-03
Abstract: Injection molding machine apparatus and method with moving platen injection and ejection actuation is provided for an injection molding machine clamp assembly configured to clamp a relatively movable platen to a relatively stationary platen. Injector structure is coupled to the relatively movable platen and is configured to actuate a molten material injection structure when the relatively movable platen and the relatively, stationary platen are closed. Ejector structure is coupled to the relatively movable platen and is configured to actuate a molded article ejection structure when the relatively movable platen and the relatively stationary platen are open.
Patent CA-2594432-A1 (CA)
Inventor: TREMBLAY BENOIT
IPC: H04W92/02
Filed: 2006-02-14
Abstract: The present invention relates to a method and nodes for performing bridging of data traffic over an access domain. For doing so, for data traffic received at an access node from a first user domain and destined to a second user domain, the access node identifies a service binding corresponding to the received data. Then, the access node tunnels the data traffic in a Unicast message addressed to an access edge node in accordance with the identified service binding. The tunnelled data traffic is then forwarded to the access edge node.  The access edge node receives the tunnelled data traffic, and identifies the service binding corresponding to the received tunnelled data traffic. The access edge node then proceeds with redirecting the tunnelled data traffic to a second access node in accordance with the identified service binding therein. The redirected tunnelled data traffic is received at a second access node, where it is detunnelled and forwarded to the second user domain. The method also provides an access node and an access edge node for performing the invention.
Patent CA-2595740-A1 (CA)
Title: Methodes et applications de soutien a la selection de systeme d'acces radio par des stations mobiles multimode
Inventor: XUE HAO
IPC: H04W74/04
Filed: 2007-08-01
Abstract: Des méthodes sont fournies pour une station mobile multimode aux fins de l'exécution une sélection de systèmes multimodes au moyen d'un algorithme de sélection de systèmes multimodes en tant que fonction des données de recouvrement multimodes. Les données de recouvrement multimodes comprennent une pluralité d'associations, dont chacune est située entre un jeu respectif de systèmes qui servent au moins une région géographique commune, et au moins certaines des associations entre les systèmes utilisant une technologie d'accès radio différente. Des méthodes sont également fournies pour un système aux fins de la préparation de données de recouvrement multimode qui comprennent une pluralité d'associations et envoient les données de recouvrement multimodes à la station mobile.
Patent CA-2597268-A1 (CA)
Inventor: DENIS DAVID
IPC: F01D5/30
Filed: 2007-08-15
Abstract: A compressor vane having a root, a tip and an airfoil portion extending between the root and the tip is disclosed. A grommet is used in conjunction with the vane and has a lip sealingly surrounding a portion of the vane root and a circumferential portion protruding around a perimeter of the lip in engagement with a surface of a platform of the vane root.  The circumferential portion has a profile similar to that of the airfoil portion.
Patent CA-2598240-A1 (CA)
Inventor: LIOU DAVID
IPC: F03B3/12
Filed: 2007-08-21
Abstract: A controllable transmission system and a method thereof are provided.  The controllable transmission system includes a first rotation device, a coupling device and a control device. The first rotation device includes a transmission shaft, a rotation body and a plurality of blade units connected with the rotation body, wherein each of the blade units includes an adjustable blade having a first and a second contact elements and having an opening corresponding to the adjustable blade. The coupling device is mounted beside the rotation device and includes a coupling unit having a first and a second contact surfaces. The control device is connected with the coupling device for controlling a movement of the coupling device to cause one of the contact surfaces positioned corresponding to a respective one of the first contact element and the second contact element.
Patent CA-2598285-A1 (CA)
Inventor: SHOULDERS STEPHEN L
IPC: F01N1/02
Filed: 2005-03-07
Abstract: A compressor apparatus having a check valve (70) having a first condition permitting downstream flow along the flowpath and a second condition blocking a reverse flow. The valve element includes a resonator (112).
Patent CA-2598417-A1 (CA)
Title: Expandable laser catheter
Inventor: WINSTON THOMAS R
IPC: A61F2/958
Filed: 1999-07-29
Abstract: Expandable laser catheters (10) for utilizing laser energy to remove obstructions (36) from body passages (34) are described. In one embodiment, the laser catheter includes a shaftway (12) having a distal end (18) including a flexible portion (20) configured in a series of radial folds. Multiple optical fibers (30), configured to transmit laser energy, extend along the shaftway and are attached to the flexible portion. An inflatable, ring-shaped balloon (22) is attached to the catheter (10) within the flexible portion (20). In use, the catheter (10) is inserted into a body passage (34) such as an artery, and advanced until the distal end (18) is adjacent to an obstruction. The balloon (22) is inflated to expand the flexible portion (20) and to bring the optical fibers (30) nearer the inner wall of the body passage. Laser energy is directed by the optical fibers (30) toward targeted regions of the obstruction (36). As the catheter is advanced and the process repeated, a core (50) is formed from the obstruction (36) and contained within the flexible portion (20). The flexible portion (20) is then contracted to hold the core (50), and the core (50) is removed from the body passage (34) by withdrawing the catheter (10).
Patent CA-2599313-A1 (CA)
Title: An absorbent article comprising a liquid transfer layer
Inventor: HELMFRIDSSON BROR-INGE
IPC: A61F13/512
Filed: 2006-03-01
Abstract: absorbent article comprising a liquid transfer layer (5) positioned between a liquid pervious bodyside liner (6) and an absorbent core (2). The liner (6) comprises a plurality of perforations (7). The liner and the transfer layer are bonded together in a plurality of bonding sites (11) covering an area of between 0.5% and 11 % of the area of the liner (6) that is circumscribed by the bonding sites and wherein each bonding site has an area of no more than 13 mm2. The combined perforated liner (6) and transfer layer (5) provides a quick inlet of liquid and a low rewet against the wearer. The liner (6) has a three-dimensional structure of alternating raised and depressed regions and the perforations (7) are present in the bottoms of the depressions (8) of said liner as seen from the body facing side of the liner.