Patent SG-11201901782T-A (SG)
Title: Container for separating microcarriers from cell culture fluids
Inventor: MORRISSEY MARTIN
IPC: B01D35/28
Filed: 2017-10-23
Abstract: WO 18/085 07 0 Al 10 10' 1 0\" FIG. 2 A (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 11 May 2018 (11.05.2018) WIPO I PCT IiiimmoimiolollmonoloommuloonmoilomovoimIE (10) International Publication Number WO 2018/085070 Al (51) International Patent Classification: BOLD 35/28 (2006.01) (21) International Application Number: PCT/US2017/057856 (22) International Filing Date: 23 October 2017 (23.10.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/416,309 02 November 2016 (02.11.2016) US (71) Applicant: EMD MILLIPORE CORPORATION [US/US]; 400 Summit Drive, Burlington Massachusetts 01803 (US). (72) Inventor: MORRISSEY, Martin; c/o EMD Millipore Corporation, 400 Summit Drive, Burlington, Massachusetts 01803 (US). (74) Agent: LEMACK, Kevin S. et al.; 176 E. Main Street, Suite 5, Westboro, Massachusetts 01581 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) (54) Title: CONTAINER FOR SEPARATING MICROCARRIERS FROM CELL CULTURE FLUIDS (57) : Containers for separating microcarriers from a cell culture fluid that offer a greater efficiency of filtration of cell cul- ture fluids containing microcarriers relative to systems described in the art. The container may include a first compartment that may include a sterile collapsible bag, an inlet port providing a fluid path into the first compartment and an outlet port providing a fluid path exiting the first compartment; and a second compartment fluid- ly connected with the inlet port of the first compartment and in- cluding a plurality of independent or discrete microcarrier receiv- ing regions defined by boundary walls which are partially or fully porous and having a porosity sufficient to retain the microcarrier s inside the second compartment, while allowing the cell culture fluid to pass through the second compartment into the outlet port of the first compartment, where the cell culture fluid can be col- lected.