baber/WOPTO huggingface dataset:
Patent DK-1820022-T3 (DK)
Inventor: KAUFMANN HITTO
IPC: G01N33/569
Filed: 2005-11-07
Granted: 2009-09-14
Abstract: Production of biopharmaceuticals from CHO cells requires generation of master-, working- and post-production cell banks of high quality, partly under GMP conditions. An optimal cryopreservation strategy is needed for each new production cell line, particularly with regard to the desire to establish production processes that are completely devoid of serum or even any animal components and to ensure robust thaw performance for reliable production. Here we describe a novel strategy employing flow cytometric (FC) analysis of Annexin V-stained cells for high-throughput characterization of CHO cell banks. Our data show that this method enables evaluation of a cryopreservation procedure just 6 h after thaw.
Patent DK-1805366-T3 (DK)
Inventor: BACK WALTER
IPC: E01D2/04
Filed: 2005-10-27
Granted: 2008-07-21
Abstract: The invention relates to a multipurpose route consisting of vertical supporting pillars and horizontal route sections which are adjacently arranged on the supporting pillars, a plurality of route sections forming at least one superimposed track or bearing surfaces for lines, and comprising a continuous cavity inside over the entire length of the multipurpose route. The supporting pillars and/or the route sections consist of laminated wood, and the longitudinal surfaces of the individual route sections are trapezoidal. The route sections are alternately arranged in relation to each other such that the oblique front sides thereof lie against each other respectively with the essential part of the surface thereof in a non-positive or positive manner.
Patent DK-1762622-T3 (DK)
Inventor: DE KREIJ ARNO
IPC: A23L29/00
Filed: 2004-01-15
Granted: 2012-01-16
Abstract: A method for the  in situ  production of an emulsifier in a foodstuff, wherein a lipid acyltransferase is added to the foodstuff. Preferably the emulsifier is produced without an increase or without a substantial increase in the free fatty acid content of the foodstuff. Preferably, the lipid acyltransferase is one which is capable of transferring an acyl group from a lipid to one or more of the following acyl acceptors: a sterol, a stanol, a carbohydrate, a protein or a sub-unit thereof, glycerol. Preferably, in addition to an emulsifier one or more of a stanol ester or a stanol ester or a protein ester or a carbohydrate ester or a diglyceride or a monoglyceride may be produced. One or more of these may function as an additional emulsifier.
Patent DK-1762537-T3 (DK)
Inventor: KUBUSCH DIETMAR
IPC: B60K15/07
Filed: 2006-09-05
Granted: 2012-04-10
Abstract: The machine has a pressurized tank (3) for carrying a gaseous fuel e.g. hydrogen, with standard conditions. A mold (10) is provided in the machine and adapts to parts of outer contour of the tank. The mold is formed from a material of large density such as steel or cast iron. The mold includes a recess (11) with a circular arc-shaped cross section for accommodation of the tank. An elastic, supporting unit is arranged in the recess. The molds also adapts to the contour of the tank of surrounding components such as fuel cell unit (2), wall and base of vehicle body compartment.
Patent DK-1883565-T3 (DK)
Inventor: MAICZ DIETMAR
IPC: B61K9/12
Filed: 2006-05-24
Granted: 2011-06-14
Abstract: The invention relates to a method for detecting wheel shapes of rail wheels with the aid of a measuring strip which consists of a row of measuring elements which are applied to the rails and which absorb the dynamic effects and which guide the corresponding electric signals of an electronic evaluation device for representing the wheel shapes. The signals are derived from the measuring elements, which displace the rails in the vertical direction and, preferably, in the transversal direction, and then an information array is formed in the evaluation device from the signals, which corresponds at least to the periphery of the wheel. The periodic signal of the shapes of the wheel is evaluated with the aid of a Fourier development.
Patent DK-1893633-T3 (DK)
Inventor: STURROCK EDWARD
IPC: A61K38/00
Filed: 2006-05-29
Granted: 2010-12-20
Abstract: This invention relates to a process for the synthesis of ketomethylene derivatives of the tripeptide Phe-Gly-Pro (“keto-ACE”, compound 5a) and analogues thereof. The synthesis process proceeds via an α,β-unsaturated keto intermediate. A key feature of the process involves a Horner-Emmons olefination of the, -unsaturated keto-phosphonate with ethyl glyoxylate. Keto-ACE analogues produced by the process of the invention display C-domain selectivity.
Patent DK-1921968-T3 (DK)
Inventor: BERTRAM ANDRE
IPC: A47L9/10
Filed: 2006-08-23
Granted: 2011-09-26
Abstract: A method for treating dust including: separating, in a vacuum cleaner, the dust into at least two fractions which differ in at least one of a size and a mass of particles of the dust; and adding a dust-binding agent to at least a first of the fraction.
Patent DK-1825461-T3 (DK)
Inventor: GEISER BERND
IPC: G10L21/038
Filed: 2006-06-30
Granted: 2009-01-26
Abstract: The method involves providing a broadband input speech signals, and determining signals components of the signals from an increased band of the signals. The temporal and spectral envelopes of the components are determined. The information of the envelopes is coded by a coder (1), and the coded information is provided to execute the increment of the bandwidth of the signals. The coded information is decoded and the temporal and spectral envelopes are generated from the coded information to create a bandwidth increased output speech signals. An independent claim is also included for a device for artificially increasing bandwidth of a speech signal.
Patent DK-2071201-T3 (DK)
Inventor: STAUCH GERT DR-ING
IPC: F16B31/02
Filed: 2007-12-11
Granted: 2010-07-05
Abstract: The shear screw (S), to fasten an electrical cable in a tubular metal clamp, has a blind hole (6) at the level of the second nominal fracture point (5). The second fracture point is towards the bottom end side (3) of the screw, with a greater strength than the first nominal fracture point (4). An opening (7) in the screw is concentric to the blind hole, but axially shorter and with the same cross section. The blind hole opening is distorted so that a tool can only be inserted into the shorter opening.
Patent DK-2174075-T3 (DK)
Inventor: CASTELAIN GILLES JACQUES
IPC: F24J3/00
Filed: 2007-07-05
Granted: 2012-01-16
Abstract: The present invention provides a secondary heat production device (5) for fitting to a closed circuit thermodynamic system associating main heat production means (1) operating by compressing a fluid and a heat exchanger (2) that are interconnected by a fluid flow channel (3). The device (5) is mainly constituted by a plurality of individual channels (8, 9) interposed between an inlet chamber (11) and an outlet chamber (13), each of the chambers (11, 13) including a respective inlet or outlet pipe (10, 12) on a common axis and presenting respective identical main sections corresponding to the total section of the individual channels (8, 9).
Patent DK-2019579-T3 (DK)
Inventor: KRONEDER CHRISTIAN
IPC: H05K7/14
Filed: 2008-07-09
Granted: 2010-09-27
Abstract: The power semiconductor module has housing (10), an extension (20), a substrate carrier (40), a circuit configuration (50) and outgoing electrical connection elements (60). The substrate carrier has a continuous recess (42), which extends from the inner main surface (44) opposite the inside of power semiconductor module to its outer main surface (46). An independent claim is also included for method for a manufacturing a power semiconductor module.
Patent DK-2043066-T3 (DK)
Inventor: WAGNER ERNST-WERNER
IPC: G08B17/00
Filed: 2006-10-11
Granted: 2011-03-28
Abstract: The device has a suction pipe system for communicating with an electrical cabinet (100) to be monitored by a suction opening and a representative air sample extracted from the cabinet through the pipe system. An early fire detection module (10) has a detection unit (11) arranged as a modular unit for detecting a fire parameter in the air sample. A controller (12) transfers an early fire detection signal in response to the detected output from the detector unit, where the module is arranged as an insertion rack for inserting into the cabinet.
Patent DK-2328264-T3 (DK)
Inventor: WINKELNKEMPER MANFRED
IPC: H02M5/27
Filed: 2009-09-29
Granted: 2012-07-23
Abstract: The converter (1) has two-pole switching cells (2) for switching positive voltage and negative voltage between poles. A set of output phase connections (U2, V2, W2) are respectively connected in series with a set of input phase connections (U1, V1, W1) via a corresponding one of the switching cells. An inductance (3) is connected with each series connection of corresponding one of the n input phase connections and corresponding one of the p output phase connections. A short-circuiting element is connected in parallel with each switching cell. An independent claim is also included for an electrical alternating current (AC) voltage system comprising an output fault current limiting inductor that is connected to n output phase connection of a direct converter.
Patent DK-2519632-T3 (DK)
Inventor: COLLARD JOSEPH
IPC: C12N15/63
Filed: 2010-12-30
Granted: 2018-07-23
Abstract: The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Insulin Receptor Substrate 2 (IRS2) polynucleotides, in particular, by targeting natural antisense polynucleotides of Insulin Receptor Substrate 2 (IRS2) polyneucleotides and Transcription factor E3 (TFE3). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of IRS2.
Patent DK-2492355-T3 (DK)
Inventor: JACKSON DAVID B
IPC: G01N33/74
Filed: 2008-11-28
Granted: 2015-07-13
Abstract: There is disclosed a molecular composition(s) of a novel tissue protective erythropoietin (EPO) binding receptor protein complex, termed NEPOR. Presence of NEPOR components on a tumour allows EPO to impinge on the survival of associated cells thereby enhancing tumour progression and negatively effecting patient survival. There is disclosed that presence of NEPOR represents a prognostic biomarker for poorer patient outcome. Thus, the method disclosed is for stratifying patients having a tumour as suitable (i.e. NEPOR not present) or non-suitable (i.e., NEPOR present) for EPO treatment, comprising: (a) isolating a tissue sample from an individual who is receiving or is a candidate for receiving erythropoietin, (b) determining the level of expression of the NEPOR gene(s) (mRNA) and/or the presence of the NEPOR gene product (protein) from the isolated tissue, and (c) correlating the presence of an NEPOR gene expression product or the presence of NEPOR protein to a physiological response to the treatment with erythropoietin. Furthermore, by disclosing the molecular compositions of NEPOR species, there are disclosed methods for rationally identifying/designing NEPOR modulating therapeutics. Thus, the present disclosure provides methods for treating neurological insults such as stroke (via enhancement of NEPOR activity) and cancer (via down-regulation of cyto-protective signaling from NEPOR).
Patent DK-2748201-T3 (DK)
Inventor: AST OLIVER
IPC: C07K16/46
Filed: 2012-08-21
Granted: 2018-02-12
Abstract: The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.
Patent DK-0378175-T3 (DK)
Inventor: KALUZA BRIGITTE DR
IPC: G01N33/577
Filed: 1990-01-09
Granted: 1995-10-02
Abstract: Chimeric monoclonal antibodies or fragments thereof are used for diagnostic assays for the quantitative immunological determination of substances in blood or serum from patients. For the diagnostic detection of substances in serum or blood from patients by binding of two monoclonal antibodies R1 and R2 which are directed against the substance, one antibody R1 of which is able to bind or is already bound to a solid phase, and the second antibody R2 carries a label, where appropriate binding of the antibody R1 to the solid phase, removal of the complex composed of R1, substance and R2, which has been formed and is bound to the solid phase, and detection via the labelling of the antibody R2, a chimeric monoclonal antibody or a fragment thereof is used at least as one of the antibodies R1 or R2.
Patent DK-0386733-T3 (DK)
Inventor: GRUNDMANN ULRICH
IPC: G01N33/577
Filed: 1990-03-07
Granted: 1995-11-20
Abstract: It has been possible to isolate the gene for placental protein 9 (PP9) from an expression cDNA gene bank by antibodies against placental protein 5. This makes possible the preparation of PP9 by genetic manipulation.
Patent DK-0404229-T3 (DK)
Inventor: GIER GERTRUDIS MARIA GERARD DE
IPC: E02F3/96
Filed: 1990-06-14
Granted: 1993-02-22
Abstract: The invention relates to a device for breaking objects consisting of concrete or similar material, which device is provided with a pair of jaws having teeth which are pivotable relative to each other about a pivot pin. The device is designed to be coupled to the end of the arm of an excavator or the like by means of a hinge pin. A strut is provided between a first jaw and the arm of the excavator, whilst a setting cylinder coupled to the arm of the excavator with one end is coupled to the second jaw with its other end, in such a manner that the second jaw can be pivoted towards and away from the first jaw by means of said setting cylinder. The device is thereby provided with a coupling piece to be coupled to the end of the arm of the excavator by means of the hinge pin, whilst the first jaw is connected with the coupling piece in a point which, when seen in the longitudinal direction of the hinge pin, is located between the hinge pin and the point of attachment of the strut to the first jaw. The device is furthermore provided with a further strut to be provided between the coupling piece and a point near the point of attachment of the strut to the arm of the excavator.
Patent DK-0402152-T3 (DK)
Inventor: KIECZYKOWSKI GERALD R
IPC: A61P3/00
Filed: 1990-06-08
Granted: 1995-12-04
Abstract: A process for the preparation of 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof which comprises:   (a) reacting 4-aminobutyric acid with a mixture of phosphorous acid and PCl3 in the presence of methanesulfonic acid; and (b) recovering said 4-amino-1-hydroxybutylidene1,1-bisphosphonic acid or salts thereof. e
Patent DK-0477220-T3 (DK)
Inventor: DOLLINGER GAVIN D
IPC: C12Q1/68
Filed: 1990-05-16
Granted: 1996-10-21
Abstract: The present invention provides methods for tagging and tracing materials using nucleic acids as taggants. The process of tagging involves altering a substance in a manner that allows for the subsequent identification of the substance by detecting the alteration. The alteration disclosed herein involves nucleic acids.
Patent DK-0441138-T3 (DK)
Inventor: BUNZ GEORG
IPC: A44C25/00
Filed: 1991-01-17
Granted: 1994-09-05
Abstract: An ornamental chain consists of a core made of at least two parallel or twisted strings (11, 12, 13) and at least one metal wire (10) passing around said core, essentially punctiform contact surfaces (K) being formed between each string (11, 12, 13) and the metal wire (10). As a result, a very "free" fastening of the peripheral metal wire (10) is achieved by the core, and the bending behaviour of the peripheral metal wire (10) is very even due to the multi-point fastening by the continuous strings (11, 12, 13). The strings are preferably formed from metal or a metal alloy so that a high mechanical stability of the core can also be achieved.
Patent DK-0492089-T3 (DK)
Inventor: JERG HELMUT DIPL-ING FH
IPC: A47L15/44
Filed: 1991-10-31
Granted: 1995-01-02
Abstract: For household appliances, in particular washing machines and dishwashers, for a more space-saving arrangement of a device for the operation of at least one dispensing apparatus (20, 30) for additional agents in household appliances, which apparatus is connected by mechanical means to a control device (40) which is provided for the operation of said apparatus and consists of mechanical control means of a programme control unit, it is proposed that the dispensing apparatus (20, 30) and the control device (40) are arranged in modules of the household appliance which are spatially separate and are movable relative to one another. <IMAGE>
Patent DK-0455288-T3 (DK)
Inventor: MORRISON ANTHONY
IPC: A23L9/20
Filed: 1991-04-16
Granted: 1994-02-21
Abstract: The invention concerns with whippable non-dairy creams with low fat levels (15-25 wt%), that possess excellent properties, like a whipping time less than 6 min. Also a production-process is described, which includes a tempering step to make the NDC whippable within 4 min.
Patent DK-0591191-T3 (DK)
Inventor: MICHAEL J BERRY
IPC: A61F9/01
Filed: 1991-07-23
Granted: 2000-03-27
Abstract: A noninvasive method is described for performing accurate and controlled reshaping of the anterior surface of the cornea in order to correct ocular refractive errors such as myopia (nearsightedness), hyperopia (farsightedness), and astigmatism. The invention uses a light source emitting a wavelength or wavelengths with correct optical penetration depth(s) to induce changes in corneal stromal collagen without damaging the corneal endothelium, together with a light delivery and control means for producing the required irradiance, exposure time, and geometric pattern, in order to achieve the desired change in corneal shape. Corneal shape is monitored before, during, and after the procedure by a corneal topography system. Anterior corneal surface cooling by a transparent heat sink is used to prevent damage to the epithelium and to Bowman's layer.
Patent DK-0556433-T3 (DK)
Inventor: DE LONGHI GIUSEPPE
IPC: F28D9/00
Filed: 1992-05-08
Granted: 1995-03-06
Abstract: The oil radiator structure (1) particularly for heating rooms comprises a main body (2) which is defined by a plurality of mutually associated radiating elements (3), inside which a hot fluid circulates; each radiating element (3) comprises at least one shaped plate-like element which has heat propagation means suitable for reducing the heat on its outer surface and for simultaneously increasing the efficiency of the radiating element. <IMAGE>
Patent DK-0649560-T3 (DK)
Inventor: WILSON DAVID A
IPC: B01D11/02
Filed: 1992-03-26
Granted: 1997-10-27
Abstract: Magnesium is separated from magnesium slag containing radioactive thorium and its daughters by solubilizing magnesium from magnesium slurry using carbon dioxide and separating magnesium from magnesium slurry containing thorium and its daughters by filtering. The process concentrates the radioactive thorium and its radioactive daughters from the magnesium slag and reduces the volume of the radioactive waste that requires disposal.
Patent DK-0591295-T3 (DK)
Inventor: BURKART AXEL E
IPC: G06K19/077
Filed: 1992-06-16
Granted: 1996-01-15
Abstract: PCT No. PCT/EP92/01356 Sec. 371 Date Apr. 19, 1994 Sec. 102(e) Date Apr. 19, 1994 PCT Filed Jun. 16, 1992 PCT Pub. No. WO93/00658 PCT Pub. Date Jan. 7, 1993An element which can be plugged into an EDP device, having a card which is equipped with components, including a processor and data memory, a frame having an exterior form, which is designed to accommodate the card, a first interface for transferring data between the element and the EDP device, and a second interface formed by contacts on the card and on the frame, for transferring data to and from the card. The exterior form of the frame is that of a diskette so that it can be inserted into a diskette station of an EDP device. The first interface between the element and the EDP device is designed in a standard fashion, so that data can be transferred using a standard read/write device already present in the diskette station of the EDP device. The frame carries a battery for supplying current via the interface to the components located on the card, and carries an additional processor and data memory for providing the element with additional processor and storage capacity.
Patent DK-0641346-T3 (DK)
Inventor: CIABATTI ROMEO
IPC: A61P31/04
Filed: 1992-11-30
Granted: 1996-07-29
Abstract: PCT No. PCT/EP92/02764 Sec. 371 Date May 26, 1994 Sec. 102(e) Date May 26, 1994 PCT Filed Nov. 30, 1992 PCT Pub. No. WO93/12115 PCT Pub. Date Jun. 24, 1993.The present invention concerns novel naphthazarin antibiotic derivatives having general formula I    <IMAGE>  (I)  and the pharmaceutically acceptable addition salts thereof.
Patent DK-0614286-T3 (DK)
Inventor: CLAASSEN HENNING J
IPC: H01H9/02
Filed: 1993-08-25
Granted: 1999-09-27
Abstract: The invention relates to a device for the remote control of video/audio units, with a housing (14) with operating elements (18) to activate functions of the video/audio units, with electric or electronic circuits to emit operating signals for the units, with a pivotable cover (12) which is movably attached to the housing and which, in one final position, covers at least some essential operating elements and, in the other final position, exposes the covered operating elements (18), and with at least one arrangement formed on the cover (12) to accommodate an interchangeable information medium. <IMAGE>
Patent DK-0668851-T3 (DK)
Inventor: CARGANICO GERMANO
IPC: A61P25/04
Filed: 1993-11-09
Granted: 1997-12-22
Abstract: PCT No. PCT/EP93/03127 Sec. 371 Date May 23, 1995 Sec. 102(e) Date May 23, 1995 PCT Filed Nov. 9, 1993 PCT Pub. No. WO94/11332 PCT Pub. Date May 26, 1994A novel arylpropionic derivative, i.e. the (+)-(S)-2-(3-Benzoylphenyl)propionic acid tromethamine salt, the process for the preparation thereof and the use thereof as an analgesic and antiinflammatory agent.
Patent DK-0624694-T3 (DK)
Inventor: PHILIPPI GERD
IPC: E04B7/02
Filed: 1994-04-28
Granted: 1997-08-11
Abstract: The connecting parts (3) and a union part are interconnected using a basic part (6) cut from a massive bar profile with units outside a vertically running toothed profile (10) for each support (7). The supports are cut away with a width which is equal to the height of the hollow cross-section of the box profile (2). The connection parts (3) and/or the union part are cut away from the massive bar profile with such a height that in the area of the toothed profile (10) they have at the bottom and top with applied supports (7) approximately the same height. At the top the union part at least tin the area of the toothed profile (10) is inclined in the same angle as the supports (7).
Patent DK-0685474-T3 (DK)
Inventor: BROUNLICH GABRIELE DR
IPC: C07D409/12
Filed: 1995-05-18
Granted: 1999-06-14
Abstract: The inventive Oxalylamino-benzofuran- and benzothienyl-derivatives are prepared by reacting the appropriate amino substituted benzofuranes and benzothiophenes with oxalic acid derivatives. The inventive compounds are suitable for the prevention and treatment of acute and chronic inflammatory processes, particularly of the airways.
Patent DK-0726760-T3 (DK)
Inventor: BENITA SIMON
IPC: A61K9/107
Filed: 1994-10-25
Granted: 1999-12-13
Abstract: The self-emulsible oil formulation (SEOF) contains an oil component and a surfactant. The SEOF is characterized in that the oil component contains an oil vector and a cationic lipid and, optionally, a lipophilic oily fatty alcohol. The oil-in-water emulsion which is formed by the mixing of the SEOF has oily droplets which are positively charged.