baber/WOPTO huggingface dataset:
Patent CA-2202676-A1 (CA)
Title: Biodegradable polyanhydrides derived from dimers of bile acids, and use thereof as controlled drug release systems
Inventor: ZHU XIAO-XIA
IPC: C08G67/04
Filed: 1997-04-14
Abstract: New biodegradable polyanhydrides  are disclosed, which are prepared by homopolymerization of dimer of bile acid, especially lithocholic acid, or bycopolymerization with linear dicarboxylic acid,  especially sebacic acid.  These biodegradable polyanhydrides have degradation kinetics and a release rate that make them particularly useful for controlled drug release. More specifically, the degradation kinetics of such anhydrides and the release rate of molecules embedded therein make them useful as matrices for controlled drug release systems.  The rates of degradation and release can be adjusted by the copolymer composition.  The near zero-order kinetrics of release of the drug embedded in the matrices made of such anhydrides, make the same particularly useful since they can deliver an active ingredient at a constant rate for long period of time,  avoiding the inauspicious saw-tooth pattern of conventional systemic administration.
Patent CA-2205341-A1 (CA)
Inventor: GLOVER DONALD
IPC: F16K27/06
Filed: 1997-05-14
Abstract: A three-piece angle stop valve comprises a valve body (10), a resilient control sleeve (12) and a handle  (14),  with no separate  fastening or  sealing element required.  The control sleeve has a stem (28) that has annular outer splines (32) and inner grooves (36) and splines (37) surrounding axially center cavity (38).  The handle has a central post (40) that intrudes into cavity and has complementary splines  (42)  that interengage with grooves (36) and splines (37) of stem section.   The handle also has an annular mid section (44) with complementary inner splines (46) that inter-engage with splines  (32)  on the outer wall of stem section  (28)  to provide significant increased torque transfer capability to turn the control sleeve within the valve body.
Patent CA-2206821-A1 (CA)
Title: Assembly for controlling and dispensing gas for a container of pressurized gas
Inventor: VICTOR OLIVIER
IPC: G05D16/06
Filed: 1997-06-03
Abstract: The assembly includes a body in which there is formed a bore (3) for letting in gas under pressure, containing an isolation valve (4) exposed to the gas under pressure, at least one pressure reducer (5), means (9) for selecting and regulating the flow rate through at least one outlet (8) for gas at reduced pressure, and a tubular member (11) for controlling the isolation valve sitting on top of the body, the isolation valve being a spool (4) which can be moved back and forth in a transverse housing (26) in the body and the opposite ends of which interact directly with curved guide ramps (18, 19) formed by the tubular control member. The direct control of the isolation spool (4) by turning the tubular member (11) simplifies the architecture of the assembly and reduces the manufacturing and servicing costs thereof.      Application to transportable bottles of gas, especially of medical oxygen.
Patent CA-2206844-A1 (CA)
Inventor: KOBAYASHI KATSUMI
IPC: H04L12/28
Filed: 1997-03-12
Abstract: Base station generates a mobile station identifier which indicates a mobi le station that a data signal is addressed thereto, and a head slot having a da ta signal when there is a data signal that has a length to be able to transmitted using one  slot of a TDMA radio channel. When there is a data signal that has a length to be not able to transmitted using one slot, base station generates a head slot and continuou s slots which contain at least a part of data signal. Base station transmits the head slot  by using the starting slot which located at predetermined position every mobile station o n the TDMA radio channel, and transmits the continuous slots by using slots which follo w the starting slot. Mobile station receives the starting slot, and stops receptio n if the starting slot is not the head slot. If the starting slot is the head slot, t he mobile station judges the mobile station identifier. Furthermore, if the mobile station identifier indicates other mobile station, the mobile station stops reception, on the other hand, if the mobile station identifier indicates itself, the mobile station receives the continuous slot.
Patent CA-2207569-A1 (CA)
Title: Cradle assembly
Inventor: GILLE MATTHIAS
IPC: F16F1/38
Filed: 1995-12-12
Abstract: A cradle assembly (10) for a motor vehicule comprises a pair of spaced side framed members (12, 14), a front cross frame member (24) and a rear cross frame member (26). The front cross frame member is connected with front ends (16, 18) of the side frame members. The rear cross frame member extends between rear ends (20, 22) of the side frame members. The frame members are formed from tubular metal blanks by a hydroforming process in which each blank has fluid pressure provided internally thereto and thereby radially expanded so that the frame members have a peripheral configuration modified with respect to an original peripheral configuration of the associated blanks. The side frame members have the amount of metal per unit length varied during the hydroforming thereof so as to present at least one longitudinal area at which i) a transverse cross section defined by the modified peripheral configuration is increased by more than 5 % of an original cross section and ii) the amount of metal per unit length is greater thanat least some other areas of the side frame members. The side frame members each have a rigid suspension mount structure constructed and arranged to mount a vehicle suspension member to the associated side frame member thereof. The rigid suspension mount is rigidly secured to the associated side frame member at the at least one longitudinal area having the transverse cross section defined by the modified peripheral configuration increased by more than 5 % of the original cross section.
Patent CA-2208594-A1 (CA)
Title: User monitoring system
Inventor: HEWETT THOMAS T
IPC: G08B25/00
Filed: 1995-12-21
Abstract: A system (100) is provided for monitoring a user in a user living area. The system includes a system controller (110) and an activity detection subsystem (112, 116, 120, 124, 128). The activity detection subsystem (112, 116, 120, 124, 128) monitors a daily living activity of the user and provides information representative of the daily living activity to the system controller (110). The system controller (110) includes a control circuit which generates a control signal in response to the daily activity information obtained by the activity detection subsystem (112, 116, 120, 124, 128).  Control information from the system controller (110) is applied by way of a control information communication channel both to the activity detection subsystem (112, 116, 120, 124, 128) and to a remote monitoring site (148). The activity detection subsystem (112, 116, 120, 124, 128) may be a system for determining the movement of the user around the home, medication compliance by the user, problems with usage of stoves or other potentially dangerous appliances, and selected auxiliary appliances.
Patent CA-2211204-A1 (CA)
Title: Prostaglandin receptor dp
Inventor: SAWYER NICOLE
IPC: C12P21/04
Filed: 1996-01-23
Abstract: A novel prostaglandin receptor has been identified and DNA encoding the receptor has been isolated, purified, sequenced and expressed in host cells.  This DNA encoding the novel prostaglandin receptor and host cells expressing the receptor are used to identify modulators of the prostaglandin receptor.
Patent CA-2212581-A1 (CA)
Title: Calibration method for transmission control clutches
Inventor: EASTMAN BRITON TODD
IPC: B60W30/18
Filed: 1997-08-22
Abstract: The hydraulically operated clutch elements of a powershift transmission have hold pressures and fast-fill times which are calibrated as a function of the rotation speed of an internal component of the transmission. The engine speed remains substantially constant and no or substantially no torque is transmitted to the output shaft of the transmission.
Patent CA-2216516-A1 (CA)
Title: Monomeric insulin analog formulations
Inventor: FRANK BRUCE HILL
IPC: C07K14/62
Filed: 1996-03-28
Abstract: The present invention discloses various parenteral pharmaceutical formulations having a protracted effect, which comprise: a sterile aqueous suspension of about 20 U/mL to about 500 U/mL insulin analog, about 5 mg/mL to about 10 mg/mL sodium chloride, about 0.2 to about 2.0 mg/mL physiologically acceptable buffer, a zinc ion content of about 0.07 mg/mL to about 0.1 mg/mL, and a physiologically acceptable preservative at a pH of about 6.5 to about 7.8;  such that less than 5 % of the analog present in the suspension is in the dissolved state.
Patent CA-2219256-A1 (CA)
Inventor: KARPPANEN ARTO
IPC: H04L9/14
Filed: 1997-03-03
Abstract: Dans un service général de radio-communication par paquets (GPRS), les données sont codées dans des blocs (F) d'une longueur donnée qui comprennent une en-tête (1) et une section (2) de données. Un intrus peut interférer avec la communication GPRS en transmettant des copies non autorisées de messages transmis ou en envoyant de faux messages, et peut également interférer avec l'intégrité de la communication. On obtient une meilleure fiabilité de la communication GPRS en modifiant le bloc (F) utilisé sur une connexion GPRS de façon à ce que d'éventuelles copies supplémentaires des blocs puissent être découvertes. Ceci peut s'effectuer en ajoutant une zone supplémentaire d'information (3) à la section (2) de données d'un bloc (F) GPRS, le contenu de la zone étant modifié entre deux blocs (F). Le contenu de la zone d'informations supplémentaire (3) peut comprendre l'identité du bloc (F), l'identité temporaire de la liaison logique (TLLI) de la connexion, l'identité IMSI ou MSISDN de la station mobile ou une identité obtenue par un algorithme générant des nombres pseudo-aléatoires. Une seconde zone d'informations supplémentaire (4) peut être ajoutée à la section (2) de données du bloc (F), la zone étant de préférence obtenue par un algorithme différent de celui de la première zone d'informations supplémentaire (3).
Patent CA-2221487-A1 (CA)
Inventor: PAPIN JEAN-PAUL
IPC: F04C2/107
Filed: 1997-11-19
Abstract: Gear pump, or Moineau pump, comprising two helical gears one inside the other, the internal helical gear, which is rotary (the rotor) having one tooth fewer than the external helical gear, which is stationary (the stator), characterized in that the rotor and the stator are made of respective materials which have respective coefficients of thermal expansion which lead to respective expansions of the rotor and of the stator which are such that an approximately constant clearance is maintained between the rotor and the stator over a range of ambient temperatures spanning between about 15.degree.C and about 300.degree.C.
Patent CA-2222950-A1 (CA)
Title: Oral veterinary fluoroquinolone antibacterial composition for extended duration of therapy and method of treating
Inventor: NICHOLS ERIC
IPC: A61P31/04
Filed: 1996-05-22
Abstract: The present invention concerns a formulation for an oral veterinary composition containing a fluoroquinolone antimicrobial agent or a pharmaceutically acceptable salt thereof, and a method of treating a microbial infection in a ruminant. The present veterinary composition, when administered orally to a ruminating animal (e.g., a cow or a feedlot calf), allows the fluoroquinolone to be readily and extensively absorbed from the rumen into the circulating blood and provides an unexpectedly extended duration of therapeutic antimicrobial blood level.
Patent CA-2224286-A1 (CA)
Title: Ionizing radiation curing of epoxy resin systems incorporating cationic photoinitiators
Inventor: MOULTON RICHARD J
IPC: C08K3/00
Filed: 1996-07-26
Abstract: Mixtures of toughened epoxy resins with cationic initiators are curable under high energy ionizing radiation such as electron beam radiation, X-ray radiation, and gamma radiation. The composition of this process consists of an epoxy resin, a cationic initiator such as a diaryliodonium or triarylsulfonium salt of specific anions, and a toughening agent such as a thermoplastic, hydroxy-containing thermoplastic oligomer, epoxy-containing thermoplastic oligomer, reactive flexibilizer, rubber, elastomer, or mixture thereof. Cured compositions have high glass transition temperatures, good mechanical properties, and good toughness. These properties are comparable to those of similar thermally cured epoxies. A mixture of epoxy resins such as a semi-solid triglycidyl ether of tris (hydroxyphenyl) methane and a low viscosity bisphenol A glycidyl ether and a cationic photoinitiator such as a diaryliodonium salt is cured by irradiating with a dosage of electron beams from about 50 to about 150 kGy forming a cross-linked epoxy resin polymer.
Patent CA-2226740-A1 (CA)
Inventor: INOUE JUN
IPC: C07D303/48
Filed: 1996-07-04
Abstract: L'invention porte sur des composés de formule générale (I) dans laquelle R?1¿ représente carboxy ou carboxamide; R?2¿ représente hydrogène ou alkyle inférieur ou R?2¿ peut être lié à R?3¿ ou R?4¿ de manière à former un cycle; R?3¿ et R?4¿ représentent chacun hydrogène, alkyle inférieur ou sulfure, ou R?3¿ et R?4¿ peuvent être liés ensemble pour former un cycle; R?5¿ représente un phényle ou un sulfonyle substitué de formule générale (III), -SO¿2?-R?7¿, (dans laquelle R?7¿ représente aryle ou amino); et n vaut 0 ou 1; ainsi qu'à des sels desdits composés et à leur procédé de production. En raison de leur capacité d'inhibition de la cystéine protéase, ces composés peuvent servir d'agent préventif ou curatif de différentes maladies dans laquelle la cystéine protéase joue un rôle, et notamment: les troubles ischémiques, les inflammations, la dystrophie musculaire, les troubles immunologiques, l'hypertension essentielle, la maladie d'Alzheimer, les saignements sub-arachnoïdiens, l'ostéoporose, etc.
Patent CA-2228336-A1 (CA)
Title: Face mask for hockey helmet or the like
Inventor: PERNICKA MARTIN P
IPC: A42B3/20
Filed: 1998-01-30
Abstract: A mesh face mask for attachment to a hockey helmet is formed of a series of horizontal and vertical wires forming a frontwardly bulged grid. The horizontally spaced vertical wires are generally straight while some of the vertically spaced horizontal wires define a wave-like configuration to improve the lateral vision of the masked helmet wearer.
Patent CA-2228741-A1 (CA)
Inventor: HOISINGTON PAUL A
IPC: B41J29/00
Filed: 1997-04-21
Abstract: In the embodiments described in the specification, electrodes (31) are bonded to the surface of a ceramic piezoelectric layer (10) by supporting electrodes having a reduced dimension on a flexible dielectric film (30) and placing the dielectric film under tension to expand the film (30) and the electrodes (31) sufficiently to conform the electrodes (31) to the desired electrode pattern on the ceramic piezoelectric layer (10). The electrodes (31) are then bonded to the piezoelectric layer (10) with an adhesive bonding agent (22) under pressure applied hydraulically so as to be distributed uniformly throughout the surface of the piezoelectric layer. In one embodiment the dielectric film (30) also carries conductor arrays (35) for connecting the electrodes (31) to remote driver chips at locations spaced from the surface of the piezoelectric layer (10).
Patent CA-2229366-A1 (CA)
Title: Process for preparing continuously variable-composition copolymers
Inventor: GORE ROBERT HOWARD
IPC: C08F210/00
Filed: 1998-02-13
Abstract: A process for the preparation of continuously variable-composition copolymers by effecting gradual changes in monomer composition during the polymerization is disclosed. Poly(meth)acrylate copolymers made by the process of the present invention have improved lubricating oil additive properties, for example, as pour point depressants, when compared to related polymer additives made by conventional means.
Patent CA-2230557-A1 (CA)
Title: Interactive molecular conjugates
Inventor: HOFFMAN ALLAN S
IPC: A61K47/48
Filed: 1996-08-30
Abstract: The combination of the capabilities of stimuli-responsive components such as polymers and interactive molecules to form site-specific conjugates which are useful in a variety of assays, separations, processing, and other uses is disclosed. The polymer chain conformation and volume can be manipulated through alteration in pH, temperature, light, or other stimuli. The interactive molecules can be biomolecules like proteins or peptides, such as antibodies, receptors, or enzymes, polysaccharides or glycoproteins which specifically bind to ligands, or nucleic acids such as antisense, ribozymes, and aptamers, or ligands for organic or inorganic molecules in the environment or manufacturing processes. The stimuli-responsive polymers are coupled to the recognition biomolecules at a specific site so that the polymer can be manipulated by stimulation to alter ligand-biomolecule binding at an adjacent binding site, for example, the biotin binding site of streptavidin, the antigen-binding site of an antibody or the active, substrate-binding site of an enzyme. Binding may be completely blocked (i.e., the conjugate acts as an on-off switch) or partially blocked (i.e., the conjugate acts as a rheostat to partially block binding or to block binding only of larger ligands). Once a ligand is bound, it may also be ejected from the binding site by stimulating one (or more) conjugated polymers to cause ejection of the ligand and whatever is attached to it. Alternatively, selective partitioning, phase separation or precipitation of the polymer-conjugated biomolecule can be achieved through exposure of the stimulus-responsive component to an appropriate environmental stimulus.
Patent CA-2230571-A1 (CA)
Title: Automatic analyzer and display method for automatic analyzer
Inventor: SATO HIROMICHI
IPC: G01N35/04
Filed: 1996-09-03
Abstract: A small automatic analyzer in which a specimen disc 12 and a reagent disc 22 are disposed at different positions in a depth direction in a this-side area of an upper surface of an analyzer housing 40, a reaction disc 3 is disposed backward from the specimen disc 12 between the specimen disc 12 and the reagent disc 22, a specimen ex-tracting and injecting unit 14 is disposed between the re-action disc 3 and the specimen disc 12, a reagent extract-ing and injecting unit 24 is disposed between the reaction disc 3 and the reagent disc 22, the specimen and reagent extracting and injecting units 14 and 24 are arranged at different positions in an oblique direction, the reaction disc 3, specimen disc 12 and reaction disc 22 each have a separate cover therefor, and the specimen extracting and injecting unit 14 and the specimen extracting and inject-ing unit 24 have a common cover therefor.
Patent CA-2231505-A1 (CA)
Title: Preparation de derives d'acide muramique de glucosaminyle
Inventor: MA FANFENG
IPC: C07K9/00
Filed: 1996-09-26
Abstract: L'invention concerne un procédé de préparation de disaccharides, tels que des peptides et des dérivés d'acide muramique de glucosaminyle. Ce procédé consiste à condenser un ester protégé d'acide muramique avec un dérivé de 1-organothio- ou 1-fluoroglucosamine en présence d'un promoteur approprié, de manière à obtenir un ester protégé d'acide muramique de glucosaminyle. On peut utiliser cet ester protégé afin de préparer des peptides de disaccharides, tels que des dipeptides de N-acétylglucosaminyl-N-acétylmuramyle, qui se sont avérés présenter une activité immunologique. L'invention concerne également des esters protégés d'acide muramique et des composés de 1-organothio- ou 1-fluoroglucosamine que l'on peut utiliser en tant qu'intermédiaires dans le procédé.
Patent CA-2231914-A1 (CA)
Inventor: VIEN RICHARD
IPC: G06Q10/06
Filed: 1998-05-01
Abstract: La présente invention se rapporte à un outil multimédia de communication dans le cadre de démarche d'obtention d'emploi. Le moyen le plus couramment utilisé lors de démarches de l'obtention d'un emploi est le curriculum vitae papier. II synthétise la formation et l'expertise du candidat sur un document. Le contenu du curriculum vitae varie d'un individu à l'autre et ne donne pas une représentation des plus précises quant aux aptitudes et allures du candidat.
Patent CA-2232637-A1 (CA)
Title: Composition containing a compound which directly or indirectly modifies the activity of endogenous t1-m protein
Inventor: SCHMIDT JOERG
IPC: A61P43/00
Filed: 1998-03-19
Abstract: The present application regards compositions containing a compound which modulates the activity of T1-M protein, the use of compounds which modulate the activity of T1-M protein, and an in vitro method for influencing the proliferation and/or differentiation potential of bone cells. Bone differentiation is a complex process in which the proliferation of osteoblasts and the formation of bone matrix play an important role. The signals inducing transition from proliferating osteoblasts to resting bone cells have not been identified up to now. Knowledge of such signals could permit the treatment of osteopetrotic and osteoporotic diseases. According to the invention it has been found that the inhibition of T1-M protein has a proliferation-enhancing effect on osteoblasts whereas its activation stimulates differentiation. Therefore, there are provided compositions which contain compounds capable of modulating the activity of T1-M protein.
Patent CA-2233278-A1 (CA)
Inventor: FALO LOUIS D JR
IPC: A61P37/00
Filed: 1996-09-27
Abstract: The present invention relates to various methods of genetic immunization for the purpose of providing antigen-specific immunity in a mammalian host, including a human host. The invention is based on the ability to direct particulate polynucleotides which express an antigenic protein or protein fragment to the cytoplasm of host target cells, such as antigen presenting cells. A directed delivery of such particulate polynucleotides to the cytoplasm of antigen presenting cells will stimulate antigen-specific CTL production, thus promoting destruction of affected cells such as neoplastic cells and virally infected cells.
Patent CA-2237998-A1 (CA)
Inventor: COLEMAN ROGER
IPC: A61P43/00
Filed: 1996-11-15
Abstract: The present invention provides a polynucleotide (mcp-4) which identifies and encodes a novel monocyte chemotactic protein (MCP-4) which was expressed in cells of NIDDM pancreas. The present invention also provides for antisense molecules. The invention further provides genetically engineered expression vectors and host cells for the production of purified MCP-4; antibodies, antagonists and inhibitors which specifically bind MCP-4; and pharmaceutical compositions and methods of treatment based on the polypeptide, its antagonists and inhibitors. The invention specifically provides for use of the polypeptide as a positive control in diagnostic assays which also allow identification of altered mcp-4 expression. These assays utilize diagnostic compositions designed from mcp-4 encoding or complementary polynucleotide sequences, including oligomers, and anti-MCP-4 antibodies.
Patent CA-2238761-A1 (CA)
Inventor: NISHIDA SEIJI
IPC: C08F216/08
Filed: 1996-11-07
Abstract: The present invention relates to a binder for a building structure comprisi ng a main ingredient, a curing agent and an accelerator for the main ingredient ; the main ingredient being an epoxy acrylate resin diluted with a reactive monomer comprising a multifunctional ester of carboxylic acid and alcohol, at least one of which contains a reactive double bond; the curing agent being an organic peroxide; and the accelerator of the main ingredient being tertiary aromatic amines containing a hydroxyl group i n a nitrogen substituent.
Patent CA-2239159-A1 (CA)
Title: Acylated enol derivatives of .alpha.-ketoesters and .alpha.-ketoamides
Inventor: PEET NORTON P
IPC: A61P37/00
Filed: 1996-11-04
Abstract: This invention relates to acylated enol derivatives of .alpha.-ketoesters and .alpha.-ketoamides. The compounds of this invention are either prodrugs of known elastase inhibitors or are elastase inhibitors in their own right and are useful in the treatment of various inflammatory diseases, including cystic fibrosis and emphysema.