baber/WOPTO huggingface dataset:
Patent NZ-552166-A (NZ)
Title: Nutritional composition for stimulating and improving the intestinal barrier integrity
Inventor: VAN TOL ERIC ALEXANDER FRANCISCUS
IPC: A23L33/00
Filed: 2004-06-22
Abstract: Use of polyunsaturated fatty acids for the manufacture of a nutritional composition for use in a method for stimulating intestinal barrier integrity, said method comprising administering to a mammal a nutritional composition comprising: (a) eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and arachidonic acid (ARA), wherein the content of long chain polyunsaturated fatty acid with 20 and 22 carbon atoms does not exceed 15 wt.% of the total fat content; and (b) at least one oligosaccharide with a DP between 2 and 60 which comprises at least 66% galactose as a monose unit and at least one oligosaccharide with a DP between 2 and 60 which comprises at least 66% fructose as a monose unit.
Patent NZ-560597-A (NZ)
Title: Improved paper dyeing process
Inventor: CHOPRA SUNIL
IPC: D21C5/02
Filed: 2007-05-08
Abstract: Disclosed is a process for dyeing paper materials, comprising preparing pulp stock suitable for a paper making process, subjecting the pulp stock to a hot dispersion process, characterised by the steps of adding a sulphur dye to the pulp stock after the hot dispersion process of the pulp stock making process, and acidifying the dyed pulp stock to fix the dye. Also disclosed is dyed paper products produced by the process.
Patent NZ-563054-A (NZ)
Title: Antitumoral tetrahydro-pyrimidines
Inventor: MARTIN LOPEZ MA JESUS
IPC: A61K31/505
Filed: 2006-05-03
Abstract: Disclosed is a compound of formula I, or a pharmaceutically acceptable salt, tautomer, prodrug, or stereoisomer thereof, wherein the dotted line represents an optional additional bond, making R1, R5, or R2 absent as appropriate, X is selected from O, S, or NRa, and wherein the other substituents are as defined in the specification. Also disclosed is a process for obtaining the compound by extracting and isolating it from the coral Meandrina meandrites. Also disclosed is the use of the compound for treating cancer.
Patent NZ-564146-A (NZ)
Title: Stable and selective formation of Hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (TINA) and process for the preparation of TINA
Inventor: FILICHEV VYACHELSAV
IPC: C07H21/00
Filed: 2006-05-24
Abstract: Provided is a flexible basestacking monomer with the general structure X - L - I1 - C - I2 wherein X is a backbone monomer unit of an oligonucleotide or an oligonucleotide analogue, or PNA, or PNA analogues, and wherein X comprises alkylenediol, L is a linker comprising an alkyl chain, an oxaalkyl chain, an azaalkyl chain, a thiaalkyl chain, carboxamide group, a thiocarboxamide group, a sulphonamide group or combinations thereof and comprises between 0-60 atoms, I1 is a monocyclic or a polycyclic aromatic ringsystem selected from the group consisting of benzene, naphthalene, azulene and bicyclic heteroaromatic ring systems, C is a conjugator selected from the group of alkyl of 1 to 12 carbons, alkeny of 2 to 12 carbons, alkynyl of 2 to 25 carbons or diazo or combinations thereof with a length of no more than 25 carbons or/and nitrogen atoms, I2 is selected from the group of bicyclic aromatic ringsystems, tricyclic aromatic ringsystems, tetracyclic aromatic ringsystems, pentacyclic aromatic ringsystems and heteroaromatic analogues thereof and such compounds with substitutions thereof. The composition can be used as a medicament targeted to specific genes or RNAs depending on the sequence of the included oligonucleotide.
Patent NZ-567865-A (NZ)
Title: Aryl-sulphonyl -carbazole derivatives as functional 5-HT6 ligands
Inventor: RAMAKRISHNA VENKATA SATYA NIROGI
IPC: C07D209/88
Filed: 2006-06-09
Abstract: Disclosed is are aryl-sulfonyl carbazole derivatives as represented by the general formula (I), wherein: the dashed line represents an optional double bond; Ar represents any one group selected from phenyl, naphthyl, monocyclic or bicyclic heteroaryl, each of which may be further substituted by one or more independent substituents which are defined as R1; R1 represents one or multiple substitutions on the benzene ring, and may represent one or more substituents as part of the Ar group and represents one or more of hydrogen, halogen, cyano, alkyl, haloalkyl, alkoxy, haloalkoxy, cycloalkyl or cycloalkoxy; R represents either hydrogen or alkyl; n represents integer either 1 or 2; and includes its possible stereoisomers. Also disclosed is the use of a compound as defined above in the manufacture of a medicament for the treatment of a disorder of the central nervous system related to or affected by the 5-HT-6 receptor (disorders such as an anxiety disorder, a cognitive disorder, or a neurodegenerative disorder, Alzheimer's disease, Parkinson's disease, attention deficit disorder or obsessive compulsive disorder, stroke, head trauma, an eating disorder or obesity).
Patent NZ-570223-A (NZ)
Title: Catheter holding device with capture elements at an angle that directly contact the catheter fitting
Inventor: EISELE ROBERT F
IPC: A61M5/32
Filed: 2007-01-11
Abstract: Disclosed is a device (90) for securing a catheter on a patient. The device comprises of: a base (96) having locating elements (100) for positioning a catheter fitting (32); a cover (98) connected to the base by a hinge; and latching elements (52, 54). The cover has capture elements (100a, 104a) that extend across the cover at an angle of 1-45 degrees to a longitudinal axis. The capture elements directly contact and compress the catheter fitting on the base.
Patent NZ-570431-A (NZ)
Title: Variants in complement regulatory genes predict age-related macular degeneration
Inventor: ALLIKMETS RANDO L
IPC: C12Q1/68
Filed: 2007-02-13
Abstract: Disclosed is a method for assessing the risk of development of, or likely progression of, age-related macular degeneration in a human subject, the method comprising the steps of determining whether the subject carries one or more polymorphisms or one or more allelic variants selected from: a) A or G at rs641153 of the complement factor B (BF) gene, or R or Q at position 32 of the BF protein; b) A or Tat rs4151667 of the BF gene, or L or H at position 9 of the BF protein; c) G or Tat rs547154 of the C2 gene; and d) C or G at rs9332739 of the C2 gene, or E or D at position 318 of the C2 protein, wherein if the subject does not have at least one of the one or more polymorphisms or al1e1ic variants, the subject is at increased risk for developing age related macular degeneration, wherein the method is not performed on a living human body.
Patent NZ-577085-A (NZ)
Title: Human monoclonal antibodies to btla and methods of use
Inventor: KORMAN ALAN
IPC: A61K39/395
Filed: 2007-11-15
Abstract: Disclosed are isolated monoclonal antibodies, particularly human monoclonal antibodies that specifically bind to BTLA with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells and methods for expressing the antibodies of the disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the disclosure are also provided. The disclosure also provides methods for detecting BTLA, as well as methods for treating various diseases, including cancer and infectious diseases, using anti- BTLA antibodies.
Patent NZ-578570-A (NZ)
Title: Preamble based uplink power control for lte
Inventor: MALLADI DURGA PRASAD
IPC: H04B7/005
Filed: 2008-02-14
Abstract: A method that facilitates generating a power control preamble for utilization in a wireless communication environment and a wireless communications apparatus that enables utilizing power control preambles in a wireless communication environment are disclosed. The apparatus comprises means for obtaining an uplink grant, the uplink grant being a first uplink grant subsequent to uplink inactivity; means for transferring an uplink power control preamble at a power level selected as a function of an open loop power control estimate; means for obtaining a power control command that alters the power level prior to transmitting uplink data to the base station; and means for transmitting uplink data at the altered power level. Also disclosed are a method that facilitates evaluating power control preambles for employment with power control in a wireless communication environment and a wireless communications apparatus that enables yielding power control commands based upon power control preambles for utilization by access terminals in wireless communication environment. The apparatus comprises means for sending an uplink grant over a downlink; means for obtaining a power control preamble sent at a power level determined from an open loop estimate; means for sending a power control command that corrects the power level prior to obtaining an uplink data transmission; and means for obtaining the uplink data transmission at the corrected power level.
Patent NZ-585488-A (NZ)
Title: Pacifier with teat and mounting shield being co-moulded
Inventor: SCHOFIELD PAUL
IPC: A61J17/00
Filed: 2008-10-23
Abstract: A soother (130) comprising a relatively flexible teat portion (129) and a relatively rigid mount portion (132). The teat portion is co-moulded to at least part of the mount portion to form an attachment therebetween. The mount portion comprises a substantially central aperture (136) defined by an aperture wall (142) which extends between inner and outer surfaces (138, 140) of the mount portion. The teat portion includes a fortified ring structure (139) that corresponds to the aperture wall such that a bond is formed between a surface of the fortified ring structure and the aperture wall. The teat portion and the mount portion are secured to one another solely by being moulded together.
Patent NZ-585667-A (NZ)
Title: Method of recording streaming video output and application state information simultaneously
Inventor: PERLMAN STEPHEN G
IPC: H04N7/50
Filed: 2008-12-04
Abstract: Disclosed is a method for low-latency streaming of interactive video. The method includes running a twitch game or application on one or more servers (402) in a hosting service centre (210). The game or application is played or used by one or more users on one or more client devices (415) remote from the hosting service centre (210). The game or application is played or used by way of compressed streaming interactive video. The compressed streaming interactive video is compressed with a finite latency of about 80ms or less such that at least one user has a perception that the twitch video game or application is responding instantly. The method also includes recording game or application state information of the twitch game or application along with the compressed streaming interactive video as the twitch game or application is being played or used.
Patent NZ-587800-A (NZ)
Title: Profiled sail boom for a sail including a thin upright-shaped vertical spar for mechanical strength
Inventor: WALDHAUSER KURT
IPC: B63B15/00
Filed: 2009-02-03
Abstract: 587800 Disclosed is a profiled sail boom (1) for a boat. The profiled sail boom (1) comprises a batten mainsail, is flexible in the horizontal direction, and has a vertical spar (21) with cords laminated in at the uppermost and lowermost points in the centre of the cross-section. Transverse webs (22) separated by wedge-shaped spacer joints (52) extend from the spar (21) in the horizontal direction at the lowermost point. Guiding tubes (49) for cords (50) are provided on the outer edges of the transverse webs (22).
Patent NZ-591056-A (NZ)
Title: Human cytomegalovirus neutralizing antibodies and use thereof
Inventor: LANZAVECCHIA ANTONIO
IPC: C07K16/08
Filed: 2009-07-15
Abstract: Disclosed is an isolated antibody, or an antigen binding fragment thereof, that is specific for an hCMV protein gB. The disclosed antibody comprises heavy and light chain variable regions as defined in the specification. The antibody is used in the treatment of hCMV infection.
Patent NZ-592096-A (NZ)
Title: Antibodies that bind to il-12 and methods of purifying the same
Inventor: HICKMAN ROBERT K
IPC: C07K16/00
Filed: 2009-10-20
Abstract: Disclosed is a method for producing a host cell protein (HCP) reduced anti-interleukin-12 (IL-12) antibody, or antigen binding portion thereof, preparation from a sample mixture comprising an anti-IL-12 antibody, or antigen binding portion thereof, and at least one HCP, and wherein said sample mixture has not been exposed to Protein A, said method comprising: Subjecting said sample mixture to a reduction in pH thus forming a primary recovery sample, wherein said reduction in pH is to between 3 and 4; Adjusting said primary recovery sample to a pH of between about 4.5 and 6 followed by; Applying said primary recovery sample to an ion exchange resin and collecting an ion exchange sample; and Applying said ion exchange sample to a hydrophobic interactive chromatography (HIC) resin, washing said resin with a 25mM sodium phosphate, 0.85 M ammonium sulphate wash buffer at pH 7, and collecting a HIC sample, wherein said HIC sample comprises said HCP-reduced anti-IL-12 antibody, or antigen binding portion thereof, preparation.
Patent NZ-593016-A (NZ)
Title: Pharmaceutical dispenser and use thereof
Inventor: LEIFELD SABINE
IPC: A61J1/03
Filed: 2009-11-14
Abstract: 593016 A medicament dispenser (1) for solid medicament portions (T), containing receiving means for an exchangeable cartridge (900) containing the medicament portions, the receiving means for the cartridge being in the form of a receiving shaft which extends in a longitudinal axial direction of the medicament dispenser, at least one locking means (410, 420) for locking the cartridge in the medicament dispenser, the locking means being a rotatably movable locking lever with two arms and with locking lugs (412, 422) on the lower part of the locking lever, and at least one means for cancelling the locking of the cartridge in the medicament dispenser, the means for cancelling the locking comprising a thrust means (300) which is movable along the receiving shaft and transfers an elastic force to the medicament portions contained in the cartridge in a column-shaped arrangement. Upon insertion of the cartridge into the receiving means the thrust means press against one or more upper parts of the locking lever, the locking lugs engaging with one or more locking profiles on the dispenser to thereby lock the cartridge in the medicament dispenser. The thrust means codes the filling level of the cartridge with tablets, and releases the locking lugs of the locking lever when there are no medicament portions remaining in the cartridge.
Patent NZ-598070-A (NZ)
Title: New highly stable aqueous solution, electrode with nanocoating for preparing the solution and method for making this electrode
Inventor: CHEN YONGGE
IPC: C25B11/04
Filed: 2006-10-23
Abstract: 598070 Disclosed is a device for the electrolytic treatment of a fluid, comprising at least one chamber for the electrolytic treatment of said fluid and at least one pair of electrodes for each chamber, said electrodes being arranged within said at least one chamber, wherein at least one of the electrodes comprises a surface coating which comprises nanoparticles of one or more metals, wherein at least 80% by weight of the particles have a diameter of between 60 and 80 nm. Also disclosed is a method for preforming the electrolysis of a fluid using the device and electrolytic acid water obtained by the device.
Patent NZ-598822-A (NZ)
Title: Formulation and method for treating plants to control or suppress a plant pathogen
Inventor: BROWER WILLIAM
IPC: A01N63/32
Filed: 2012-03-15
Abstract: 598822 Disclosed is a formulation effective for preventing, suppressing, treating or controlling bacterial or fungal mediated disease or decay in plants, including their fruits and/or harvestable parts; said formulation comprising an antagonistic microorganism and a booster composition, wherein said booster composition comprises: a) about 3 parts Kaolin clay; b) about 1 part yeast extract; c) about 1 part Yucca plant extract; and d) about 1 part calcium-source material, wherein the formulation does not comprise a microbe mixture comprising a mixture of beneficial bacteria including the group consisting of Bacillus subtilis, Bacillus licheniformis, Bacillus azotoformans, Bacillus megaterium, Bacillus coagulans, Bacillus pumilis, Bacillus thuringiensis, Bacillus sterotermophilis, Paenbacillus polymyxa, Paenbacillus durum, Azotobactor chroococcum, Pseudomonas aureofaceans, and Pseudomonas fluorescens. Further disclosed is a method for improving the ability of an antagonistic microorganism to prevent, suppress, treat or control bacterial or fungal mediated disease or decay in plants, including their fruits and/ or harvestable parts, the method comprising contacting a plant with a formulation as described above.
Patent NZ-603236-A (NZ)
Title: Boronate ester compounds and pharmaceutical compositions thereof
Inventor: ELLIOTT ERIC L
IPC: A61K38/05
Filed: 2009-06-16
Abstract: 603236 Disclosed are dipeptide boron esters of formula (II) where P is C(O)-2,5-dichlorophenyl and the amino acids are glycine and luecine in a gly-leu arrangement. Also disclosed are crystalline forms of two examples of compounds of formual (II) which are: 2,2’-{ 2-[(1R)-1-({ [(2,5-dichlorobenzoyl)amino]acetyl} amino)-3-methylbutyl]-5-oxo-1,3,2-dioxaborolane-4,4-diyl} diacetic acid and 4-(R,S)-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid. The compounds are useful in treating cancer.
Patent NZ-621972-A (NZ)
Title: Nanoparticle comprising rapamycin and albumin as anticancer agent
Inventor: DESAI NEIL P
IPC: A61P35/00
Filed: 2008-03-07
Abstract: Disclosed is the use of a composition comprising nanoparticles that comprise rapamycin or a derivative thereof and a carrier protein in the manufacture of a medicament for treating cancer in an individual, wherein the composition is used in combination with another chemotherapeutic selected from the group consisting of an antimetabolite agent, a Platinum-based agent, an alkylating agent, a tyrosine kinase inhibitor, an anthracycline antibiotic, a vinca alkaloid, a proteasome inhibitor, a topoisomerase inhibitor, an AKT kinase inhibitor, a therapeutic antibody, a p110α-specific inhibitor, an agent affecting a signalling pathway involving TORC1, an agent affecting a signalling pathway involving TORC2, an inhibitor of the PI3K/Akt pathway, a colchicine or thiocolchicine dimer or derivative thereof, and an interferon.
Patent NZ-622129-A (NZ)
Title: Amino-substituted imidazopyridazines
Inventor: HITCHCOCK MARION
IPC: C07D487/04
Filed: 2012-09-05
Abstract: Provided are amino-substituted imidazopyridazines of the general formula (I), wherein A is a benzofuran and the other variables are as defined in the specification. Examples of the compounds include 4-{ [3-(4-Methoxy-1-benzofuran-2-yl)imidazo[1,2-b]pyridazin-6-yl]oxy} butan-1-amine and 2-{ [3-(1-benzofuran-2-yl)imidazo[1,2-b]pyridazin-6-yl]oxy} -1-(pyridin- 3-yl)ethanamine. The compounds are inhibitors of MKNK1 or MKNK2 kinase. The compounds are useful in the treatment of cancer.
Patent NZ-627476-A (NZ)
Title: 2,4-d saline soluble granule and preparation method therefor
Inventor: SUN GUOQING
IPC: A01P13/00
Filed: 2012-05-02
Abstract: Disclosed is a 2,4-Dichlorophenoxyacetic acid (2,4-D) water-soluble granule formulation , comprising components with the following weight percentage: 5-80% 2,4-D salt (calculated as 2,4-D acid); and a water-soluble inorganic salt (e.g. ammonium phosphate, ammonim nitrate, ammonium chloride, potassium phosphate, etc.) as the balance. The 2,4-D water-soluble granule is suitable as a herbicide for controlling annual or perennial gramineae weeds and certain broadleaved weeds in soybean fields and other Leguminosae fields, such as amaranth, knotweed, goosefoot, nightshade, Xanthium sibiricum, barnyard grass, green bristle grass, crabgrass, glutinous millet, etc. Also disclosed is a method for the preparation of the water-soluble granule formulation which does not require a surfactant or a binder.
Patent NZ-727919-A (NZ)
Title: Humanized anti-tau antibodies
Inventor: HOLGATE ROBERT
IPC: A61K39/00
Filed: 2015-06-26
Abstract: Provided herein is an isolated antibody or antigen-binding fragment that specifically binds tau, the antibody or fragment comprising a heavy chain variable (VH) region and a light chain variable (VL) region having amino acid sequences set forth herein. Also provided are methods of preventing or treating a tauopathy in a subject, comprising administering to a human in need of therapy for a tauopathy with one or more antibodies or fragments as described herein, wherein the antibodies or antigen-binding fragment are administered under conditions and in an amount effective to prevent or treat the tauopathy.
Patent NZ-733329-A (NZ)
Title: Microbiocidal control in the processing of poultry
Inventor: LIIMATTA ERIC
IPC: A22C21/00
Filed: 2016-01-13
Abstract: This invention provides processes comprising contacting at least one unopened defeathered poultry carcass with water containing a microbiocidal composition, optionally opening and eviscerating at least one unopened defeathered poultry carcass that was wetted; subjecting at least one eviscerated poultry carcass to inside-outside washing with water containing a microbiocidal composition; placing at least one eviscerated poultry carcass in a chill tank into contact with chill water containing a microbiocidal composition; contacting parts of poultry resulting from processing of poultry containing a microbiocidal composition. The water in these processes contains a microbiocidal composition comprising I) one or more surfactants and II) a microbiocidal amount of a biocide. The surfactants include amine oxides and/or betaines. The biocides include various chlorine-based and bromine-based biocides; chlorine dioxide; and peracetic acid. In particular, the microbiocidal composition comprises synergistic combinations of amine oxide and/or betaine surfactants and biocides such that the microbiocidal compositions provide an enhanced microbiocidal effect when applied to poultry.
Patent NZ-733578-A (NZ)
Title: Detachable threaded connection with asymmetric coating
Inventor: Schaffer Markus
IPC: E21B17/042
Filed: 2015-12-29
Abstract: Screw joints for screwing together steel pipes in the crude oil and natural gas production industry are prone to fretting, and may require greasing to prevent damage to the threads. A screw joint has a tubular element having an internal thread (7) and a tubular element having an external thread (6), both threads being provided with a phosphate layer (8, 9) as a first layer, wherein the internal thread comprises a ceramic material (11) having a friction-reducing effect as a second layer and the external thread comprises a varnish layer (10) with a binder of an organic polymer as a second layer, in which solid lubricant particles are distributed. The first layer consists of manganese phosphate with the addition of nickel salts, and the layer thickness of said ceramic layer is less than 1 μm. The tubular elements have second contact surfaces adjacent the threads, and the second contact surfaces comprise sealing surfaces that cooperate with each other to form a sealing seat and further comprise shoulder surfaces that cooperate with each other.