baber/WOPTO huggingface dataset:
Patent EP-1392360-A2 (EP)
Inventor: BANDER NEIL
IPC: A61K39/395
Filed: 2002-05-30
Abstract: Modified antibodies, or antigen-binding fragments thereof, to the extracellular domain of human prostate specific membrane antigen (PSMA) are provided. The modified anti-PSMA antibodies, or antigen-binding fragments thereof, have been rendered less immunogenic compared to their unmodified counterparts to a given species, e.g., a human. Pharmaceutical compositions including the aforesaid antibodies, nucleic acids, recombinant expression vectors and host cells for making such antibodies and fragments are also disclosed. Methods of using the antibodies of the invention to detect human PSMA, or to ablate or kill a PSMA-expressing cell, e.g., a PSMA-expressing cancer or prostatic cell, either in vitro or in vivo, are also provided.
Patent EP-1399576-A2 (EP)
Title: Testsystem zur bestimmung von gentoxizitäten
Inventor: WIESMUELLER LISA
IPC: C12Q1/6897
Filed: 2002-02-28
Abstract: Gegenstand der Erfindung ist ein Verfahren, welches den Nachweis von gentoxischem Stress in lebenden Säugerzellen durch Detektion aller bisher beschriebenen Typen der DNA-Rekombination und weiterhin von Mutationen als Antwort auf Noxen ermöglicht. Der Nachweis basiert auf der Detektion der Fluoreszenz intakter autofluoreszierender Proteine oder der Lumineszenz mittels intakter biolumineszierender oder Chemilumineszenz-Substrate umsetzender Enzyme, zeichnet sich durch eine kurze Reaktionszeit im Stundenbereich aus und erlaubt insbesondere durch die Verwendung eines retroviralen Vektorgerüstes die Übertragung des Testsystems auf unterschiedliche Säugerzellen und auf lebende Versuchstiere.
Patent EP-1423537-A2 (EP)
Inventor: KMIEC ERIC B
IPC: A61P25/28
Filed: 2002-08-07
Abstract: L'invention porte sur des compositions et procédés de prévention et traitement de maladies neurodégénératives, et spécialement de la maladie de Huntington à cette fin l'invention utilise des oligonucléotides monobrin modifiés en vue d'une altération ciblée de la séquence génétique du gène de la maladie de Huntington, et sur des procédés de traitement et prévention de ladite maladie les utilisant.
Patent EP-1419557-A2 (EP)
Inventor: CLARK GAVIN
IPC: H01R24/52
Filed: 2002-07-23
Abstract: A subminiature coaxial connector (SMA) includes a shell, dielectric and conductor element that includes a biasing element that engages an interface contact tip and biases the interface contact tip into electrical contact against an electrical circuit, such as a trace on the circuit board without soldering, and adjusts for relative movements created by thermal mismatch.
Patent EP-1428107-A2 (EP)
Inventor: AUSTIN JAMES LEONARD
IPC: G06F15/18
Filed: 2002-09-10
Abstract: Each of a cluster of computing balls (1) contains within its housing (3) a photosensitive device (51) for receiving light from a light source (5) and converting it into energy to power a processing chip (2). There is thus wireless transmission of power to the computing balls (1), which also carry out wireless communication of data with one another. The computing balls (1) may be poured at random into a container (6), and intercommunicate to form a computing device.
Patent EP-1454446-A2 (EP)
Inventor: DAOU FADI
IPC: H04B10/155
Filed: 2002-11-26
Abstract: This invention describes methods and optical signal devices that minimize the optical loss when combining the optical signals from a plurality of laser sources of typically differing wavelengths, said sources being tunable or non-tunable.
Patent EP-1415339-A2 (EP)
Title: Method for the parallel production of an mos transistor and a bipolar transistor
Inventor: BERTHOLD ADRIAN
IPC: H01L27/06
Filed: 2002-07-02
Abstract: The invention relates to a method for the parallel production of an MOS transistor in an MOS area of a substrate (1) and a bipolar transistor in a bipolar area of said substrate (1). The method comprises the creation of an MOS preconditioning structure in the MOS area, whereby the MOS preconditioning structure contains a region (13) provided for a channel, a gate dielectric (14), a gate electrode layer (15, 19) and a masking layer (21a, 21b, 22) on the gate electrode layer (15, 19). In addition, a bipolar preconditioning structure is created in the bipolar area, said structure comprising a conductive layer (20) and a masking layer (21a, 21b, 22) on the conductive layer (20). The masking layer (21a, 21b, 22) is reduced in the vicinity of the gate electrode. To establish a gate electrode and a base connection region, the gate electrode layer (15, 19) and the conductive layer (20) are jointly structured.
Patent EP-1414352-A2 (EP)
Title: Traitements pour un patient souffrant d'une insuffisance cardiaque congestive
Inventor: LATTOUF OMAR M
IPC: A61B17/068
Filed: 2002-12-06
Abstract: L'invention concerne deux procédures thérapeutiques présentant un caractère invasif minimal, destinées en particulier à des patients souffrant d'une insuffisance cardiaque congestive, ainsi que des dispositifs et des systèmes pour de telles procédures. Une procédure consiste à obtenir un passage présentant une valve à travers la paroi ventriculaire gauche du patient, au niveau de l'apex du coeur du patient, et à avancer des instruments à travers ce passage à valve pour relier les valvules de la valve du coeur du patient, par exemple la valve mitrale, dans une configuration de « noeud papillon » pour éviter ou pour minimiser une régurgitation à travers ladite valve. La seconde procédure consiste à faire avancer une électrode de stimulation et un dispositif d'implantation d'électrode de stimulation à travers un trocart dans la poitrine du patient, et à implanter l'électrode de stimulation dans une zone épicardique exposée de la paroi cardiaque du patient. Cette électrode de stimulation présente une électrode de pénétration qui est fixée à l'intérieur de la paroi cardiaque. L'une de ces procédures ou les deux procédures peuvent être effectuées sur un patient souffrant d'une insuffisance cardiaque congestive. Des dispositifs améliorés pour ces procédures comprennent un dispositif de préhension présentant un caractère invasif minimal, doté d'une lumière intérieure, permettant de faire avancer des éléments de connexion ou d'autres instruments à travers le dispositif jusqu'à la partie distale de celui-ci. D'autres dispositifs améliorés comprennent un instrument d'implantation d'électrode de stimulation fixé de manière amovible au niveau de son extrémité distale à la paroi cardiaque exposée pour faciliter la pénétration de l'électrode de stimulation dans la paroi cardiaque. D'autres instruments améliorés comprennent un connecteur de valvule doté d'un faisceau de cordages tendineux situés à une extrémité du connecteur de valvule.
Patent EP-1345381-A2 (EP)
Inventor: PARK IN-HO
IPC: G06Q10/00
Filed: 2003-03-10
Abstract: Disclosed is an apparatus (262) for providing device information via a
network (230) and method thereof. A message processing unit processes input and
output messages into database schema based on registration request messages from
domestic devices (290,292). The information producing unit dynamically produces
updated information based on the data stored in the database and provides it in
a web document format. In one embodiment, the information managing unit manages
characteristic information e.g., location information, identification and additional information of a device. The data
processing unit processes a transaction of the data stored in the database. The
characteristic information and the additional information of the device existing
in the home network (260) created in an XML format is converted into a
predetermined document structure and stored in the storing unit, a database. Accordingly,
the remote users can have different access authority from each other by
assuring independence between the domestic devices and the remote devices (220,250),
and easily use the home network service by providing the device information
in a web document format.
Patent EP-1359468-A2 (EP)
Inventor: SENTOKU KOICHI
IPC: G03F9/00
Filed: 2003-04-29
Abstract: A system which manages a plurality of semiconductor
exposure apparatuses holds TIS information representing
the characteristics of the respective semiconductor
exposure apparatuses. In a semiconductor exposure
apparatus, a parameter value is optimized on the basis of
AGA measurement results obtained using a set parameter
value and another parameter value and AGA measurement
estimation results obtained by virtually changing the
parameter value. Whether to reflect the optimized
parameter value in another industrial device is decided on
the basis of the TIS information. If it is decided to
reflect the optimized parameter value, the parameter value
of another semiconductor exposure apparatus is optimized
by the optimized parameter value. In this manner, the
optimization result of a parameter value by a given
industrial device can be properly reflected in another
industrial device, realizing efficient parameter value
setting.
Patent EP-1336802-A2 (EP)
Inventor: ANTOINE DOMINIQUE
IPC: F24C7/06
Filed: 2000-02-16
Abstract: The cooker has upper and lower walls (5), and a lateral wall (4). The tubular heating element can be rotated from the horizontal working position. The ends of the element (11) are connected (12) to an electric supply, passing through a hole (8) in the lateral wall (4). A spring (16) holds the element in the working position and pressed flats (20,30) on the element retain the end of the spring.
Patent EP-1385015-A2 (EP)
Inventor: SCHMALZ STEVEN CHRISTOPHER
IPC: H02H3/04
Filed: 2003-07-16
Abstract: A tester (21) for  in situ  testing of a plurality of circuit breakers (7 1 -7 n )
having a range of rated currents and multiple trip functions, includes a plurality of
power resistors (31 1 -31 12 ) of known impedance, an electronic switch (59 1 -59 12 )
associated with each power resistor connecting the resistor in series with the load
terminal (15) of the circuit breaker under test (7 n ), and a controller (33) that turns on a
number of the switches (59 1 -59 12 ) selected to collectively draw through the associated
power resistors (31 1 -31 12 ) a test current that is a function of the rated current and
sufficient to trip the circuit breaker (7 n ) within a selected time window. Turn on of
the electronic switches (59 1 -59 12 ) is also controlled to generate a current waveform
appropriate for the trip function being tested. In a self test mode, the value of each of
the power resistors (31 1 -31 12 ) is verified as being within limits.
Patent EP-1355007-A2 (EP)
Inventor: MATTEN NICHOLAS
IPC: E03C1/04
Filed: 2000-01-19
Abstract: The shower combination has a front panel (12) on which a shower functional unit (13) is arranged and that consists of mineral glass. The front panel is transparent at least in some areas, especially from its rear to its front. The front panel is at least partly in the form of a mirror, especially mirrored with a mirror coating on the rear of the glass panel.
Patent EP-1416217-A2 (EP)
Inventor: AIGNER KURT
IPC: F16M11/42
Filed: 2003-07-18
Abstract: The distance between at least one of the castor wheels (3, 4) and the central axis (2) for the support can be varied.  The workpiece is supported on a plate (10) whose height can be adjusted relative to the chassis (1), which can be moved on castor wheels.
Patent EP-1396736-A2 (EP)
Inventor: YAMAZAKI MASAO
IPC: G01N15/02
Filed: 1998-03-11
Abstract: A flow cell 2, a composite lens 15, and first to third detectors
16 to 18 are arranged in this sequence in the light pathway of light
emitted from a laser light source 1. The composite lens 15 is
configured by a convex lens 15a, and lens elements 15b and 15c.
These lenses have different focal lengths. When the posture of
the composite lens is correct, light impinging on the convex lens
forms an image on the first detector. Therefore, the positioning
of the composite lens is enabled. When particles in the flow cell
are irradiated with laser light, forward scatter is produced.
Forward small angle scatter having a small scattering angle
impinges on the first lens element 15b to be collected thereby,
and is then received by the second detector 17. Forward large angle
scatter having a large scattering angle impinges on the second lens
element 15c in the outermost periphery to be collected thereby,
and is then received by the third detector 18 which is remotest
from the composite lens.
Patent EP-1443210-A2 (EP)
Inventor: HUNDT GERD
IPC: F04C15/00
Filed: 2003-10-08
Abstract: The motor-pump unit has two internal gear pumps (e.g. 2), each with sprocket (2.1), eccentric hollow gear (2.2) and gear axle (2.3) in side disks (2.4), with pump axes coinciding. The sprockets of the two pumps are identical. At least one of the pumps has an electric motor (1) with a rotor (1.3) of U-shaped axial section fitting round its pump.
Patent EP-1420204-A2 (EP)
Inventor: KONDO TETSUYA
IPC: F21W107/17
Filed: 2003-10-10
Abstract: The shape of a reflector is to be made
conspicuous to improve the appearance of a headlamp
assembly. 
In the invention, a headlamp assembly 5 includes electric
bulbs 7 and 8, a reflector 10, a lens 13, and a case 32.
Between the reflector 10 and the case 32 are formed gaps
which result from a difference in shape between the
reflector and the case. Blindfold portion 105 and 106 for
filling up the gaps are formed integrally with the
reflector 10. The blindfold members 105 and 106 are
provided with reflecting surfaces which project a black
portion of the ground or of an inner surface of the case
32. With the reflecting surfaces of the blindfold members,
a contrast is created between the blindfold member and
reflecting surfaces of the reflector 10 to make the
reflecting surface shape of the reflector conspicuous.
Patent EP-1385166-A2 (EP)
Inventor: SAKO YOICHIRO
IPC: H04N7/173
Filed: 2000-08-25
Abstract: A data recording medium having recorded thereon in advance: first digital data
including at least work data; second digital data recorded by a different recording
method from the recording method of the first digital data; and identification
information for carrying out identification proper to the recording medium.
Patent EP-1438920-A2 (EP)
Inventor: JUNG CLEMENS
IPC: A47L15/46
Filed: 2003-11-12
Abstract: The invention relates to a method of operating a dishwasher with a central
control unit, by measuring the turbidity of the rinsing liquid and establishing
the course of the programme as a function of the turbidity of the rinsing liquid.
In a pre-rinse operation, measurement values determined by a sensor system
are derived from the soiling of the rinsing liquid and supplied to the control
unit, which calculates therefrom associated parameters for the further course
of the programme and establishes the latter correspondingly.
Patent EP-1382583-A2 (EP)
Inventor: MACQUART PHILIPPE
IPC: B32B17/10
Filed: 1995-12-22
Abstract: Transparent substrate is coated with a pile of thin layers, with reflective properties in the infrared and/or in the solar radiation domain. A transparent substrate (1), notably of glass, provided with a pile of thin layers incorporates at least one metal layer (4) with properties in the infrared, arranged between an underlying oxide anchoring layer (3) deposited on a first coating of dielectric based material (2) and an upper protective layer (5) surmounted by a second coating of dielectric based material (9). With a view to preventing the modification of the properties of the pile, in the case where the carrier substrate (1) is subjected to a heat treatment of the tempering or bending type, the second dielectric based coating includes at least one oxygen diffusion barrier layer (7) and the functional metal layer is deposited directly on the anchoring layer. Independent claims are also included for: (a) a low emission or antiglare multiple glazing incorporating such substrate; (b) a laminated glazing incorporating such substrate; (c) a method for the fabrication of the substrate; (d) utilization of the substrate in which the substrate is curved, annealed or tempered; (e) an assembly of glazing incorporating the tempered, curved or annealed substrate.
Patent EP-1398306-A2 (EP)
Inventor: GREEN CARTER B
IPC: A23L27/00
Filed: 2001-02-02
Abstract: The invention relates to a composition comprising a compound having the
general formula (I):
 
wherein n is an integer from 2 to 6; and a suitable carrier. The composition
has long-lasting cooling sensate effects.
Patent EP-1363136-A2 (EP)
Inventor: DIXON WILLIAM THOMAS
IPC: G01R33/561
Filed: 2003-05-15
Abstract: A method and system are provided for acquiring images using a magnetic
resonance imaging (MRI) system (100). The method comprises the step of
applying (101,102) a plurality of steady-state free precession (SSFP) radiofrequency
(RF) excitation pulses in a selected pattern of varying amplitudes
and phases such that signals corresponding to the pattern of pulses are
substantially immune to magnetic field inhomogeneity of the MRI system.
The pulses have substantially equal spacing between all neighboring pulses
and between successive groups of pulses. The method further comprises the
step of reading (101,105) a plurality of signals corresponding to the pulses.
Patent EP-1424697-A2 (EP)
Inventor: HSU SHENG TENG
IPC: G11C16/04
Filed: 2003-07-24
Abstract: A common bit/common source line high density 1T1R
(one transistor/one resistor) R-RAM array, and method for
operating said array are provided. The R-RAM array
comprises a first transistor with a drain connected to
a non-shared bit line with a first memory resistor. The
gates of the first, second, third, and fourth transistors
are sequentially connected to a common word line. The R-RAM
array comprises at least one common bit line. A second
memory resistor is interposed between the drain of the
second transistor and the common bit line. Likewise, a
third memory resistor is interposed between the drain of
the third transistor and the common bit line. A common
source line is connected to the sources of the third and
fourth transistors. The R-RAM array comprises m rows of
 n  sequential transistors.
Patent EP-1408543-A2 (EP)
Inventor: FUJIMORI JOJI
IPC: H01L21/56
Filed: 2003-07-30
Abstract: A method of forming a solder ball (161) includes
the steps of forming an electrode pad (71) on a substrate,
forming an insulating layer (81) having a first opening (B)
at a position of the electrode pad, filling the
first opening with solder paste (90) that include solder
and first resin, and applying a heating process to
the solder paste so as to form a solder ball (161) on the
electrode pad and to form a cured resin member (171) of
the first resin across a border between the
electrode pad and the substrate.
Patent EP-1536345-A2 (EP)
Title: Programmable configuration integrated circuit
Inventor: SUN ALBERT
IPC: G06F15/78
Filed: 2003-12-18
Abstract: A system-on-a-chip integrated circuit that includes a configurable logic array,
a processor core, and a memory adapted to store instructions for a mission function, and
instructions for a configuration load function used to load configuration data on to a non-volatile
configuration store on the integrated circuit via an input port on the integrated
circuit from an external source. The processor fetches and executes the instructions from
the memory. Instructions for a configuration function are stored in the memory, by
which configuration data is transferred from the configuration store to configuration
points in the configurable logic array.
Patent EP-1332753-A2 (EP)
Inventor: LENNON PAULA
IPC: A61Q1/14
Filed: 2003-01-21
Abstract: Solid composition comprises an emulsifier with a hydrophilic-lipophilic balance (HLB) of 1-8 and a semi crystalline solid polymer with a m.pt. below 70degreesC comprising a crystallizable organic side chain and/or a crystallizable organic sequence in the main chain, the polymer having a number-average molecular weight above 2000. An Independent claim is also included for a cosmetic method for make-up removal or for cleansing the skin, lips and visible organs, comprising applying a composition as above.
Patent EP-1355398-A2 (EP)
Inventor: MORISOT LOUIS
IPC: H01R4/24
Filed: 2003-04-16
Abstract: The electrical apparatus (100) has a constricted section (10) holding electrical conductors and having a forward and rear (120) section. The rear section holds metallic strip connections (126A,126B,126C) which extend vertically from the electrical conductor axis.
Patent EP-1474156-A2 (EP)
Title: Matieres issues des cellules stromales de la moelle osseuse destinees a la formation de vaisseaux sanguins et a la production de facteurs angiogeniques et trophiques
Inventor: CHOPP MICHAEL
IPC: A61K35/30
Filed: 2003-01-14
Abstract: L'invention concerne une substance thérapeutique permettant d'induire l'angiogenèse et la vasculogenèse. Cette substance thérapeutique contient des facteurs d'induction de l'angiogenèse et de la vasculogenèse isolés de cellules souches conjointement avec une thérapie cellulaire pharmaceutiquement acceptable. L'invention concerne également une méthode permettant d'amplifier la production des facteurs d'induction de l'angiogenèse et de la vasculogenèse sécrétés, cette méthode consistant à exposer des cellules souches à un composé et à co-cultiver ces cellules souches avec ce composé afin d'accroître la production de facteurs d'induction de l'angiogenèse et de la vasculogenèse. L'invention concerne en outre des facteurs d'induction de l'angiogenèse et de la vasculogenèse isolés et purifiés issus de cellules souches destinées à être utilisées dans une thérapie. L'invention concerne un procédé permettant d'obtenir les facteurs d'induction de l'angiogenèse et de la vasculogenèse tel qu'ils sont décrits ci-dessus, ce procédé consistant à isoler des cellules souches mésenchymateuses humaines du tissu et à les purifier avant leur différenciation, puis à les développer par culture ces cellules souches mésenchymateuses afin de produire un outil destiné à la thérapie neurologique et musculo-squelettique. L'invention concerne enfin des cellules souches mésenchymateuses isolées et développées par culture sous l'action d'un composé requis, lesquelles cellules permettent de différencier et de produire un phénotype cellulaire souhaité utile pour la réparation tissulaire.
Patent EP-1504258-A2 (EP)
Inventor: MATSON ROBERT S
IPC: C12M1/00
Filed: 2003-04-22
Abstract: L'invention concerne des dispositifs de détection servant à effectuer une détection multianalyte sur un substrat solide (11); des méthodes de préparation desdits dispositifs et leur utilisation dans des procédés d'analyse et de diagnostic. Les dispositifs de détection comprennent un substrat solide (11) fabriqué avec un réseau de points de détection présentant un détecteur d'analyte (15) lié au substrat (11) par un ligand de liaison universel (13). Le ligand de liaison universel (22) peut lier plusieurs détecteurs d'analyte (25A, 25B et 25C) pour former un réseau multifonctionnel. L'invention concerne en outre un procédé de production desdits dispositifs de détection, et des méthodes de dosage mettant en oeuvre une technologie de micro-impression.
Patent EP-1492965-A2 (EP)
Inventor: SIRVEN JACQUES
IPC: F16F9/512
Filed: 2003-03-28
Abstract: The invention concerns a damper, in particular for motor vehicle, comprising a cylinder containing a hydraulic fluid, a main piston (1) actuated by a rod (3) defining in the cylinder a first chamber (2a) and a second chamber (2), said second chamber containing the rod, a hydraulic fluid reservoir (6) and a valve (10) placed in the hydraulic fluid flow between the first chamber and the second chamber, said valve comprising a mobile check valve (28) co-operating with a seat (30) and means designed to press the check valve on its seat. The invention is characterized in that it further comprises filtering means mounted (16) in parallel with the valve (10), adapted to generate a filtering control pressure acting on the check valve, the control pressure depending on the pressure differential at the inlet and the outlet of the valve.