baber/WOPTO huggingface dataset:
Patent JP-2008525367-A (JP)
IPC: A61K9/20
Filed: 2005-12-14
Abstract: A multiparticulate, pharmaceutical dosage form containing at least one antibiotic which is sparingly wettable with aqueous media or sparingly soluble in aqueous media and a combination of carrageenan and tricalcium phosphate and optionally sucrose ester. Also, an administration system having this dosage form arranged in a drinking straw with at least one barrier device for single administration, optionally together with a conveying liquid.
Patent JP-2008525239-A (JP)
Title: 金型およびプラスチック製品成形方法
IPC: B29C45/33
Filed: 2005-12-23
Abstract: 底部および側壁が設けられたプラスチック製品を製造するための金型（２０）であって、少なくとも第１および第２の金型部（２１，２２）を備え、該第１および第２の金型部は両方で少なくとも１つの金型キャビティを少なくとも部分的に規定し、第１の方向に移動可能であり、少なくとも１つの金型キャビティ（１００）は、少なくとも１つの第１の部分（１０１）、特に底部形成部と、少なくとも１つの第２の部分（１０２）、特に側壁形成部とを含み、該第１の金型部には、少なくとも１つの固定壁部（２４）が設けられ、該固定壁部は第１の可動壁部（２６）を支持し、該第１の可動壁部は第１の方向と角度をなす少なくとも第２の方向に各固定壁部に対して移動可能であり、第１の可動壁部には金型キャビティに臨む側に第２の可動壁部（３５）が設けられ、該第２の可動壁部は第１の可動壁部に対して前進位置と待避位置との間を移動可能であることを特徴とする金型。
Patent JP-2008527086-A (JP)
Title: 電荷輸送材料
IPC: C08G73/06
Filed: 2005-12-23
Abstract: 電荷輸送材料、およびその製造方法を提供する。
Patent JP-2008526817-A (JP)
Title: 新規のピロロジヒドロイソキノリン
IPC: A61P35/00
Filed: 2006-01-11
Abstract: 本発明は、細胞性（過剰）増殖の効果的なインヒビター及び／又は癌細胞におけるアポトーシスのインデューサーである新規のピロロジヒドロイソキノリン誘導体に関する。
Patent JP-2008528334-A (JP)
IPC: B41J2/175
Filed: 2006-01-26
Abstract: A fluid ejection system includes a first fluid ejection head comprising a first nozzle plate that includes a first set of fluid ejection nozzles capable of ejecting first fluid drops and a second fluid ejection head comprising a second nozzle plate that includes a second set of fluid ejection nozzles capable of ejecting second fluid drops. The second nozzle plate is substantially opposing to the first nozzle plate. The first set of fluid ejection nozzles are offset from the second set of fluid ejection nozzles.
Patent JP-2008530106-A (JP)
Title: ９−置換テトラサイクリン
IPC: C07C237/26
Filed: 2006-02-09
Abstract: 本発明は、式（Ｉ）の化合物、あるいはそれらの互変異性体または薬学的に受容可能な塩を提供し、ここで、Ｒ １ は、以下の（ＩＩ）および（ＩＩＩ）から選択される部分であり；ｎは、１〜２の整数であり；Ｒ ２ は、水素、アミノ、−ＮＲ ６ Ｒ ７ 、必要に応じて置換した１個〜１２個の炭素原子のアルキル、必要に応じて置換した６個、１０個または１４個の炭素原子のアリール、必要に応じて置換した２個〜１２個の炭素原子のアルケニル、必要に応じて置換した２個〜１２個の炭素原子のアルキニル、ハロゲン、および必要に応じて置換した５員〜１０員ヘテロアリール環から選択され、該ヘテロアリール環は、１個〜４個のヘテロ原子を有し、該ヘテロ原子は、別個に、Ｎ、ＯおよびＳから選択され；Ｒ ３ 、Ｒ ４ 、Ｒ ５ 、Ｒ ６ およびＲ ７ 、Ｒ ８ は、本明細書で定義されるとおりである。
Patent JP-2008532322-A (JP)
Title: 固体照明に用いられる多層ポリマー発光ダイオード
IPC: H01L51/50
Filed: 2006-03-01
Abstract: 多層ポリマー発光ダイオード（ＰＬＥＤ）は、発光層である有機金属エミッタとブレンドした半導体ポリマーと、該発光層の適当な電子注入及びホール注入側の電子輸送層及びホール透明層の一方または双方とを用いて示される。輸送層は、ホール注入電極及び発光性ポリマーの間のエネルギーポテンシャルギャップと、電子注入電極及び発光性ポリマーの間のエネルギーポテンシャルギャップとを低下させる。これらのデバイスを調製するための溶媒処理に基づく手法も開示される。当該手法では、発光層を形成するための発光性ポリマーの非極性溶媒をベースとする溶液、及び、輸送層を形成するための極性溶媒をベースとする溶液を用いて、設置すべき多層として望ましくないエッチング及び他の相互作用を最小化する。「純粋な」白色光のそれに全てが近い、安定なＣｏｍｍｉｓｓｉｏｎ  Ｉｎｔｅｒｎａｔｉｏｎａｌｅ  ｄｅ  ｌ’Ｅｃｌａｉｒａｇｅ座標、安定な色温度、及び安定な色レンダリング指標を有する照明品質白色光を得ることができる。これらの多層白色発光ＰＬＥＤは、液晶ディスプレイ及び固体照明に適用するバックライトとして有用である。
Patent JP-2009162342-A (JP)
Title: Engine mount structure
Inventor: ANDO KEIICHI
IPC: F16F15/121
Filed: 2008-01-09
Abstract: <P>PROBLEM TO BE SOLVED: To solve the problem of a conventional engine mount that, when a muffler is remodeled for generating an acceleration sound for having a difference in engine sound quantity between an acceleration/deceleration time and a stationary travel time, an unnecessary sound is generated in deceleration, and that, when using an electronically controlled mount for the engine mount, the size, the weight, and the price of the device are increased.  <P>SOLUTION: An engine mount 1 comprising an elastic member having two cavities 3 and 4 on the rear side and the front side of a part where an engine E is placed is provided with the engine mount structure for an automobile in which a number of projections 5 are formed in the rear cavity 3 on the rear side around the part where the engine E is placed.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009162176-A (JP)
Title: Compressor
Inventor: IMAI TAKAYUKI
IPC: F04B39/06
Filed: 2008-01-09
Abstract: <P>PROBLEM TO BE SOLVED: To provide a compressor capable of forming a heat insulation structure for reducing heat transmission to a coolant gas in an intake chamber while preventing detachment of a heat insulation member, preventing mis-assembly, and reducing a number of parts.  <P>SOLUTION: In this compressor, a rear housing 14 is coupled with a cylinder block 11 via a valve-port organizer 13, an intake chamber 26 opened toward the valve-port organizer 13 is blocked in the rear housing 14, and an intake chamber heat-insulation member 40 covering an inner wall 14c of the rear housing 14 is provided in the intake chamber 26. The intake chamber heat-insulation member 40 is integrally provided with a detachment-prevention spring piece 53 for preventing the intake chamber heat-insulation member 40 from being detached from the intake chamber 26, and a pressure-contact spring piece 54 for pressing the intake chamber heat-insulation member 40 against the valve-port organizer 13. Also, the detachment-prevention spring piece 53 is exposed to the outside of the intake chamber 26 from between the rear housing 14 and the intake chamber heat-insulation member 40.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009161689-A (JP)
Title: Enclosure member for electronic equipment and method for producing molding comprising the enclosure member
Inventor: KANAZAWA SHINICHI
IPC: C08L67/04
Filed: 2008-01-09
Abstract: <P>PROBLEM TO BE SOLVED: To provide an enclosure member for electronic equipment which, in spite of containing a biodegradable material of vegetable origin, has improved heat resistance and is hard to damage.  <P>SOLUTION: The enclosure member for electronic equipment includes a powdery or fibrous vegetable filler (A) and a resin component which binds the vegetable filler (A), wherein the resin component includes a polylactic acid (B), a polycarbonate (C), and a polyester (D) having three or more contiguous methylene groups, has a salami structure in which the polycarbonate (C) is dispersed in the polyester (D), and the polyester (D) is dispersed in the polylactic acid (B), and the amounts of (A) to (D) is such that (A)>(B)≥(C)≥(D).  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009160889-A (JP)
Title: Ball-point pen tip
Inventor: ISHIKAWA ATSUSHI
IPC: B43K1/08
Filed: 2008-01-10
Abstract: <P>PROBLEM TO BE SOLVED: To provide a ball-point pen tip, the bottom wall of a ball holding chamber of which enables a tip structure with a larger ink collecting volume than ever to be easily manufactured.  <P>SOLUTION: In the ball-point pen tip, the bottom wall of the ball holding chamber of a tip main body of which has an ink circulating hole and at least three ink circulating grooves radially extending from the ink circulating hole at a center. By insertingly seating a ball in the bottom wall and caulking a tip part towards the inside, the ball-point pen tip is produced in which the ball is rotatably held under the condition that some part of the ball is projected above the tip edge. With a nearly polygonal cone-like sizing tool having at least the equivalent number of corners as the number of the ink circulating grooves. By press-working the corner parts of the sizing tool so as to locate between the ink circulating grooves, the nearly polygonal conical surface having at least the equivalent number of corners as the number of the ink circulating grooves is formed at the bottom wall.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009167846-A (JP)
Title: Screw compressor
Inventor: FUJIWARA HIDEKI
IPC: F04C18/52
Filed: 2008-01-11
Abstract: <P>PROBLEM TO BE SOLVED: To restrain discharge pulsation and a torque variation in a screw compressor.  <P>SOLUTION: This screw compressor 1 has a screw rotor 40 forming a plurality of spiral grooves 41, 41, etc. and a plurality of gate rotors 50A and 50B having gates 51, 51, etc. meshing with the spiral grooves 41, 41, etc. The screw compressor 1 compresses gas by a plurality of compression spaces 23, 23, etc. formed of the spiral grooves 41, 41, etc. and the gates 51, 51, etc., and discharges a refrigerant from a plurality of discharge ports 73 and 73 arranged at each gate rotor 50A and 50B. At this time, timings for discharging the refrigerant from the plurality of discharge ports 73 and 73 are displaced from each other.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009176862-A (JP)
Title: Substrate treatment apparatus
Inventor: KANAYAMA KOJI
IPC: H01L21/677
Filed: 2008-01-23
Abstract: <P>PROBLEM TO BE SOLVED: To provide a substrate treatment apparatus capable of preventing a decrease in degree of vacuum and contamination in an exposure apparatus.  <P>SOLUTION: An interface block 5 of the substrate treatment apparatus 500 is provided with a degassing unit DG. The degassing unit DG subjects a substrate to a degassing treatment after an edge exposure treatment by an edge exposure unit EEW and before an exposure treatment by an exposure apparatus 6. The degassing unit DG reduces the pressure in a chamber by a vacuum pump while being wherein the substrate is stored in the chamber. The pressure in the chamber is made sufficiently low and then reaction products produced during the edge exposure treatment is vaporized from a resist film on the substrate and a base film (for example, an antireflective film) therebelow and discharged to be securely removed.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009176059-A (JP)
Title: Operation recognition method for moving object
Inventor: ISHIKAWA SEIJI
IPC: G06T1/00
Filed: 2008-01-24
Abstract: <P>PROBLEM TO BE SOLVED: To provide an operation recognizing method for a moving object for automatically and quickly recognizing the operation of a target moving object regardless of an observation direction.  <P>SOLUTION: This operation recognizing method for a moving object comprises: an inherent space data preparation process for preparing inherent space data A in which the frame image data A of each basic operation of the moving object are displayed with dots, and for integrating the data into a database in advance; and a recognition process for comparing inherent space data B in which the frame image data B of the target moving object B are displayed with dots with the inherent space data A for each basic operation, and for selecting the inherent space data A whose distance from the inherent space data B is the shortest, and for recognizing the operation of the moving object B. The frame image data A for each basic operation are obtained from a compressed image prepared by making the moving object A perform a basic operation, and photographing the moving object A performing a basic operation from multi-directions by using a plurality of image input means, and overlapping a plurality of continuous frame images obtained for each image input means after weighting the frame images.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009172950-A (JP)
Title: Composite material sheet and composite component equipped therewith
Inventor: MORINAGA HIROTSUGU
IPC: B32B27/36
Filed: 2008-01-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a composite material sheet which is more excellent in impact resistance than a conventional sheet made of a fiber-reinforced plastic simple substance.  <P>SOLUTION: The composite material sheet 10 is arranged on a surface of a body to be protected 30 and comprises a non-fiber-reinforced plastic layer 14 which is arranged at a side of the body to be protected 30 and is formed of polycarbonate and a fiber-reinforced plastic layer 12 which is arranged outside the non-fiber-reinforced plastic layer and contains aramid fiber or carbon fiber and a resin.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2008169112-A (JP)
Title: Shelf board for manufacturing flat panel display substrate
Inventor: SUZUKI SHUNICHI
IPC: H01J11/20
Filed: 2008-01-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a shelf board for manufacturing a flat panel display substrate by which the flat panel display substrate having excellent surface properties is manufactured.  <P>SOLUTION: The shelf board on which the flat panel display substrate is placed to carry out heat treatment has ≥5° glossiness or ≥5% image clarity and preferably has ≤2.0×10<SP>-6</SP>/°C thermal expansion coefficient, ≥40 MPa bending strength and ≥30 GPa Young's modulus.  <P>COPYRIGHT: (C)2008,JPO&INPIT
Patent JP-2009180785-A (JP)
Title: Heating rotor and image heating device having heating rotor
Inventor: KAINO TOSHIYA
IPC: G03G15/20
Filed: 2008-01-29
Abstract: <P>PROBLEM TO BE SOLVED: To provide a heating rotor, preventing contamination due to separation offset and long-term endurance, and maintaining durability, and an image heating device having the heating rotor.  <P>SOLUTION: This heating rotor 10 is used for an image heating device 62 for heating a developed image T supported by a recording material P. The heating rotor includes at least a substrate 11, an elastic layer 12 and a mold release layer 13, wherein the material of the mold release layer coming into contact with the developed image is fluororesin, the surface of the mold release layer is provided with a number of pores 13h, and when the proportion of the total area of the pores in the whole surface area of the mold release layer is defined as a numerical aperture, the numerical aperture is ≥1% and ≤40%.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009181303-A (JP)
Title: Electronic card
Inventor: HIGASHICHI AKIHIRO
IPC: B42D15/10
Filed: 2008-01-30
Abstract: <P>PROBLEM TO BE SOLVED: To provide an electronic card enabling prevention of failure of an electronic circuit incorporated in the electronic card by effectively discharging static electricity to the electronic card.  <P>SOLUTION: This electronic card has: a connector having a plurality of contacts, and a housing holding the contacts; a substrate connected with the contacts and mounted with the electronic circuit; and a container case having a first shell formed of an electrically conductive material, and positioned on a side facing a face on one side of the substrate, and a second shell formed of the electrically conductive material, and positioned on a side facing a face on the other side of the substrate. The contacts are held in a state in which the contacts are exposed inside an opening formed in a first face formed on a front face in the insertion/removal direction of the connector in the housing. The container case is provided with an electrostatic shielding unit formed of an electrically conductive material, and positioned at least partially in an exposed state on a surface of the first face.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009180970-A (JP)
Title: Optical member, backlight unit, and display device
Inventor: NOGUCHI ASAKO
IPC: F21Y103/00
Filed: 2008-01-31
Abstract: <P>PROBLEM TO BE SOLVED: To provide an optical member, a backlight unit and a display device, capable of observing visually a defect observable visually through a liquid crystal panel when a backlight turned on, clearly by the optical member only, and capable of evading the defect from flowing into a following process, even when the defect affecting image quality is generated.  <P>SOLUTION: In the optical member, a light emission face of a light diffusion sheet 9 is joined with a light incident face of an optical sheet 10 via an adhesive layer 16. The adhesive layer 16 has performance capable of observing visually the defect of 0.05 mm<SP>2</SP>clearly on a light emission face of the optical sheet 10, when irradiating a light incident face of the light diffusion sheet 9 with light, has the maximum value of a loss factor tanδ, that is a ratio of a storage shear modulus to a loss shear modulus, within a value of 1.2 or more to 1.7 or less in a range of -20°C or more to -10°C or less, and has a loss factor of 0.2 or more and less than 1.7 at an ambient temperature.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2008156656-A (JP)
Title: Fluorescent substance and its manufacturing method, composition containing fluorescent substance, light emitting device, image displaying device and illuminating device
Inventor: YOSHINO MASAHIKO
IPC: C09K11/08
Filed: 2008-01-31
Abstract: <P>PROBLEM TO BE SOLVED: To provide a high performance fluorescent substance that is the one emitting green fluorescence and excelled in a conversion efficiency and color purity for blue light or near-ultraviolet light.  <P>SOLUTION: The fluorescent substance is one satisfying conditions of (i)-(v) described below: (i) an emission peak wavelength at the time of exciting with light with 400 nm or 455 nm of peak wavelength is at least 510 nm or not more than 542 nm; (ii) an emission peak half band width at the time of exciting with light with 400 nm or 455 nm of a peak wavelength is 75 nm or less; (iii) an external quantum efficiency at the time of exciting with 400 nm or 455 nm light of a peak wavelength is 0.42 or more, where the external quantum efficiency defined by (external quantum efficiency) = (internal quantum efficiency) × (absorption efficiency); (iv) at least one surface part of the fluorescent substance is made of a substance containing oxygen; (v) the fluorescent substance contains a metallic element (M<SP>II</SP>) able to have atomic valence of di- or tri-valence, at the same time, a ratio of the mole number of M<SP>II</SP>element to the total mole number of a divalent atom contained in the fluorescent substance is larger than 1% and less than 15%.  <P>COPYRIGHT: (C)2008,JPO&INPIT
Patent JP-2009180664-A (JP)
Title: Translucent member and timepiece
Inventor: SUZUKI KATSUMI
IPC: C03C17/42
Filed: 2008-01-31
Abstract: <P>PROBLEM TO BE SOLVED: To provide a translucent member having reflection prevention function and secured scratch resistance, and also to provide a timepiece equipped therewith.  <P>SOLUTION: A cover glass 1 as the translucent member is equipped with a translucent base material 10. The base material 10 has a reflection prevention layer 11, and a lubrication layer 12 provided along a surface layer of the reflection prevention layer 11 on at least a part of its body surface part 10A. The lubrication layer 12 is formed of a fluorine-based surfactant.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2008226826-A (JP)
Title: Electrical connector
Inventor: DI BORGO PHILIPE POZZO
IPC: H01R13/64
Filed: 2008-02-01
Abstract: <P>PROBLEM TO BE SOLVED: To provide an electric connector that can proactively detect misassembly of connector components when a rear cover is fitted.  <P>SOLUTION: The electric connector 1 has: a connector housing (3) inside which pins (2) are housed and which has at the front an insertion portion (3<SB>A</SB>) into which a counterpart connector (40) is inserted, and at the rear a coupling portion (3<SB>B</SB>); a sealing member (35); a rear holder (6) which has at the front a mating cavity (6<SB>C</SB>) that is fixed to the coupling portion, and at the rear a cover installation portion; and a rear cover (20) which is mounted to the cover installation portion via sliding motion. Latching portions (11, 11) are provided in locations adjacent to the cover installation portion, engaging portions (5) into which the latching portions (11, 11) engage are provided in the holder mounting portion of the connector housing (3), and the sliding motion of the rear cover (20) is blocked if the latching portions (11, 11) are in a state of non-engagement with the engaging portions (5) when the rear holder (6) is attached to the connector housing (3).  <P>COPYRIGHT: (C)2008,JPO&INPIT
Patent JP-2009183169-A (JP)
Title: Latching tool for hanging bush cutter
Inventor: ARAHATA KOJI
IPC: A01D34/68
Filed: 2008-02-04
Abstract: <P>PROBLEM TO BE SOLVED: To provide a latching tool for hanging a bush cutter, enabling the hanging position of the bush cutter by a shouldering band to be changed arbitrarily and easily.  <P>SOLUTION: The latching tool for hanging the bush cutter is equipped with a plate-shaped latching tool body 30 attached and fixed to an operation rod 7, and having a plurality of latching holes 31-35 formed at a prescribed interval along the longitudinal direction of the operation rod 7, and a ring-shaped hanging metal fitting 50 to be passed through the latching hole 31-35 of the latching tool body 30 and composed of a rod-shaped material. A through groove hole 40:41-44 having a groove width β smaller than the diameter ϕ or thickness of the rod-shaped material constituting the hanging metal fitting 50 is formed in the catching tool body 30 so as to connect the lower parts of the plurality of the catching holes 31-35 to each other, and the thickness α of one terminal part 52, 52 of the hanging metal fitting 50 in the upper and lower direction or right and left direction is thinned than the groove width β so as to pass the through groove hole 40:41-44.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009194077-A (JP)
Title: Electromagnetic wave shield material and method of manufacturing the same
Inventor: KATO KEI
IPC: B32B15/08
Filed: 2008-02-13
Abstract: <P>PROBLEM TO BE SOLVED: To provide an electromagnetic wave shield material where lines of a conductive material layer are formed straight and the appearance of the conductive material layer is appropriate, and to provide a method of manufacturing the electromagnetic wave shield material.  <P>SOLUTION: A number of dots 26 are formed on a transparent base material 21 by a material soluble to water or a solvent, allowing a thin-line gap 21a to remain. Then, a conductive material layer 22 consisting of a conductive material is formed on the dots 26 and in the gap 21a between the dots 26. Then, a number of dots 26 are dissolved by water or a solvent permeating the inside of the conductive material layer 22, and the dots 26 and the conductive material layer 22 on the dots 26 are removed while allowing only the conductive material layer 22 formed in the gap 21a between the dots 26 to remain. A thickness Y of the conductive material layer 22 and a thickness X of the dots 26 satisfy conditions of 0.5 μm≤X≤1 μm, 0.01 μm≤Y≤0.5 μm, and Y≤1/2X.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009195376-A (JP)
Title: Method and apparatus for measuring heart stroke of fishes
Inventor: YOSHIDA MASAYUKI
IPC: A61B5/1455
Filed: 2008-02-20
Abstract: <P>PROBLEM TO BE SOLVED: To provide a test inspection method which provides a result simply and speedily and which is excellent also in view of animal protection in order to solve the problems that a water examination using fishes and a toxicity test performed by dissolving a substance in water adopts many methods of putting a plurality of fishes into water to be inspected and investigating a death rate of the fishes and a method of measuring the cardiac potential of the fishes in place of the method of investigating the death of the fishes, but the kinds of fishes are limited and execution is difficult.  <P>SOLUTION: Hemoglobin contained in blood of a vertebrate has a property of absorbing near-infrared rays. In a heart strokes, fullness and pumping out of the blood to atriums of heart and ventricles are repeated. Thus, when variation of the blood amount (that is a Hemoglobin amount) of a heart portion can be measured, the heart strokes is observed indirectly. By applying the concept to the fishes, the heart strokes of the fishes are non-invasively measured under water and the variation of the heart strokes is monitored, thereby simplifying and accelerating the water examination and the toxicity test.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2008133303-A (JP)
Title: INHIBITOR FOR TUMOR NECROSIS FACTOR alpha
Inventor: MULLER GEORGE W
IPC: A61K31/40
Filed: 2008-02-25
Abstract: <P>PROBLEM TO BE SOLVED: To provide a pharmaceutical composition reducing a TNF α (tumor necrosis factor) level in mammals.  <P>SOLUTION: The pharmaceutical composition for inhibiting TNF α contains a compound expressed by formula in an amount effective for inhibiting TNF α. New nitriles are inhibitors of the tumor necrosis factor α and phosphodiesterases and can be used to conquer cachexia, endotoxic shock, retrovirus replication, asthma and inflammatory conditions. A typical embodiment is 3-phthalamido-3-(3',4'-dimethoxyphenyl)propionitrile.  <P>COPYRIGHT: (C)2008,JPO&INPIT