baber/WOPTO huggingface dataset:
Patent EP-3914599-A1 (EP)
Inventor: LIU JUN O
IPC: A61P25/28
Filed: 2020-01-23
Abstract: The present invention provides a new class of non-immunosupressive FK506 analogs which are FKBP-selective, small-molecule BMP agonists with modest potency therepeutics for tissue repair and regeneration. Also disclosed herein are methods for making and use of these compounds.
Patent EP-3884428-A1 (EP)
Inventor: GEORGESCU WALTER
IPC: G06V10/764
Filed: 2020-05-29
Abstract: A CNN is applied to a histological image to identify areas of interest. The CNN classifies pixels according to relevance classes including one or more classes indicating levels of interest and at least one class indicating lack of interest. The CNN is trained on a training data set including data which has recorded how pathologists have interacted with visualizations of histological images. In the trained CNN, the interest-based pixel classification is used to generate a segmentation mask that defines areas of interest. The mask can be used to indicate where in an image clinically relevant features may be located. Further, it can be used to guide variable data compression of the histological image. Moreover, it can be used to control loading of image data in either a client-server model or within a memory cache policy. Furthermore, a histological image of a tissue sample of a tissue type that has been treated with a test compound is image processed in order to detect areas where toxic reactions to the test compound may have occurred. An autoencoder is trained with a training data set comprising histological images of tissue samples which are of the given tissue type, but which have not been treated with the test compound. The trained autoencoder is applied to detect tissue areas by their deviation from the normal variation seen in that tissue type as learnt by the training process, and so build up a toxicity map of the image. The toxicity map can then be used to direct a toxicological pathologist to examine the areas identified by the autoencoder as lying outside the normal range of heterogeneity for the tissue type. This makes the pathologist's review quicker and more reliable. The toxicity map can also be overlayed with the segmentation mask indicating areas of interest. When an area of interest and an area identified as lying outside the normal range of heterogeneity for the tissue type, and increased confidence score is applied to the overlapping area.
Patent EP-3983376-A1 (EP)
Title: Making ethylenediaminetetraacetic acid
Inventor: CHAKRABORTY DEBOLEENA
IPC: C07C229/16
Filed: 2020-06-03
Abstract: Provided is a method of making ethylenediaminetetraacetic acid (EDTA) comprising the steps: (a) providing a reaction mixture (a) comprising ethylenediamine (EDA) and glycolonitrile (GN), wherein reaction mixture (a) comprises 0% to 0.1% by weight, based on the weight of reaction mixture (a), of any base having pKa of the conjugate acid (PKaH) of 13 or higher; (b) causing or allowing reaction mixture (a) to react to form a dinitrile (DN) compound; (c) bringing the DN into contact with aqueous solution of a base having pKaH of 11 or higher, and causing or allowing the resulting mixture to react to form a diacid compound (DA); (d) causing or allowing the DA to react, either sequentially or simultaneously, with additional GN to form products (Pd); (e) causing or allowing products (Pd) to react with a base having pKaH of 11 or higher, to form EDTA. Also provided is a composition comprising a diacid/dinitrile compound (DADN) wherein each -R has the structure:
Patent EP-3984201-A1 (EP)
Title: Systems and methods providing a multi-cloud microservices gateway using a sidecar proxy
Inventor: MESTERY KYLE ANDREW DONALD
IPC: G06F9/445
Filed: 2020-06-04
Abstract: A method includes, in a constellation of clients including a first client and a second client, receiving, at the first client, a connection request from the second client, retrieving endpoint reachability data associated with the second client and transmitting, to a server, a connection request based on the endpoint reachability data. The first client receives, from the server and based on the connection request, endpoint reachability information associated with the second client and starts a bidirectional connection with the second client. A direct or indirect tunnel is established between the first client and the second client. The tunnel is set up based on a table which maps a first connectivity option associated with the first client to a second connectivity option associated with the second client to determine whether to establish the direct tunnel or the indirect tunnel between the first client and the second client.
Patent EP-3983429-A1 (EP)
Inventor: KROL EWELINA
IPC: C07K14/005
Filed: 2020-06-04
Abstract: The invention relates to the amino acid sequences of individual recombinant Zika virus proteins or recombinant virus-like particles comprising at least two fragments of Zika virus proteins. In both types of sequence, the E structural protein or only the cytoplasmic domain of E protein and / or the prM structural protein were used. Moreover, in some sequences, the fragment of tick-borne encephalitis virus E protein was used. The invention in the form of amino acid sequences of recombinant proteins or recombinant virus-like particles has a potential therapeutic use to prevent Zika virus infection as an immunogenic component for the preparation of vaccines. The invention in the form of recombinant proteins or recombinant virus-like particles with amino acid sequences according to the invention can be used as an  in vitro  diagnostic antigen for the detection of flavivirus infections, in particular Zika virus, tick-borne encephalitis virus and Dengue virus as a component of diagnostic tests.
Patent EP-3991397-A1 (EP)
Inventor: TSAI CHIA-YANG
IPC: H04N1/60
Filed: 2020-06-11
Abstract: The disclosed method may include (1) receiving an input datum to be processed using a non-linear function to produce an output datum, (2) comparing the input datum to a plurality of indexes of a lookup table, where the indexes designate input endpoints of a plurality of piecewise-linear sections approximating the non-linear functions, and where the lookup table further includes, for each of the indexes (a) a slope of the piecewise-linear section corresponding to the index, and (b) an axis intercept of the piecewise-linear section corresponding to the index (2) selecting, based on comparing the input datum to the plurality of indexes, an index that designates the piecewise-linear section associated with the input datum, and (4) calculating, using the slope and the axis intercept corresponding to the selected index, the output data corresponding to the input datum. Video processing systems employing such a method are also disclosed.
Patent EP-4007728-A1 (EP)
Title: Tamper-evident closure
Inventor: DOMBROWSKI ALAN R
IPC: A61M5/00
Filed: 2020-07-31
Abstract: The disclosed tamper-evident closure (100) encloses a medical access device, such as a vascular access device (200), such that it will be visibly apparent if the medical access device contained in the tamper- evident closure becomes exposed. The tamper-evident closure cannot be reapplied over the medical access device in a way to look the same as it did prior to exposing the medical access device. The tamper-evident closures comprise a holding cavity (110), a securing mechanism (160), and an apparent release. The disclosed tamper- evident closures are well suited for securing a medical access device that has an access point for delivering fluid to a patient or removing fluid from a patient.
Patent EP-4182642-A1 (EP)
Inventor: SCHOLLENBERGER FREDERICK SCOTT
IPC: G01F1/84
Filed: 2020-07-14
Abstract: A meter electronics (20) for using a stiffness measurement to compensate a fluid property measurement is provided. The meter electronics (20) comprises an interface (601) configured to communicatively couple to a sensor assembly (10) and receive sensor signals from the sensor assembly (10), and a processing system (602) communicatively coupled to the interface (601). The processing system (602) is configured to determine a fluid property value based on the sensor signals and correct the fluid property value with a fluid property correction value, the fluid property correction value being correlated with a current stiffness value of the sensor assembly.
Patent EP-4017286-A1 (EP)
Inventor: BURBIDGE ADAM
IPC: A21D13/50
Filed: 2020-08-20
Abstract: La présente invention concerne des formulations comestibles croustillantes comprenant des fibres, des protéines et une teneur limitée en glucides et sensiblement exemptes de graisse et de sucre. L'invention concerne également des procédés de fabrication desdites formulations et leur utilisation dans des produits alimentaires.
Patent EP-4013885-A1 (EP)
Title: Biological indicator for determining the efficacy of a steam or heat sterilization process and its method of use
Inventor: LOMBARDÍA ESTEBAN
IPC: C12Q1/22
Filed: 2020-08-13
Abstract: A biological indicator for determining the efficacy of a steam or heat sterilization process. The biological indicator comprises a set of microbial spores, a sensor protein exogenous to the microbial spores, a fluorophore, and a culture medium. The method of use of this biological indicator for determining the efficacy of a steam or heat sterilization process.
Patent EP-3935260-A1 (EP)
Inventor: KLEINE ADRIAN
IPC: E21B43/00
Filed: 2020-03-06
Abstract: A method, comprising receiving input data representing a subterranean formation, defining a grid representing the input data, with the grid including cells. The method also includes identifying at least one of the cells in which kerogen is present based on the input data, simulating hydrocarbon movement within the kerogen using the grid, and generating a model of hydrocarbon expulsion to pore space based on the simulating.
Patent EP-3940373-A1 (EP)
Title: Inspection device and method
Inventor: NARUSE YOSUKE
IPC: G01N21/88
Filed: 2020-02-25
Abstract: This inspection device comprises: an image-capturing unit which obtains an evaluation workpiece image that is captured with a plurality of predetermined illumination light emission patterns in order to obtain an optimized illumination light emission pattern with which the influence of non-defective product variations of a workpiece can be suppressed while defects in a workpiece are emphasized; an image area setting unit which sets a plurality of image areas associated with a plurality of different labels; an optimization calculation unit which generates a first index of which the output value increases as a difference between an image area associated with a non-defective label and an image area associated with a defective label increases, and a second index of which the output value increases as a difference or contrast between the image areas associated with the non-defective label increases, and calculates an illumination light emission pattern for inspection such that the first index becomes larger and the second index becomes smaller; and a determination unit which performs image processing on an inspection workpiece image captured with the illumination light emission pattern for inspection, and determines a pass/fail label of a workpiece to be inspected.
Patent EP-4013520-A1 (EP)
Inventor: HEYMANS JOACHIM
IPC: A63B71/02
Filed: 2020-09-18
Abstract: Die Erfindung betrifft eine Vorrichtung (1) zum Befestigen einer Haltestange (4) an einem Trampolin (2), umfassend: ein Gehäuse (6), das eine Aufnahme (10) für die Haltestange (4) und eine Aufnahme (11) für einen Fuß (5) des Trampolins (2) umfasst, wobei die Aufnahmen (10, 11) so ausgelegt sind, dass eine starre Verbindung zwischen dem Trampolin-Fuß (2) und der Haltestange (4) herstellbar ist. Außerdem ist ein Anschlag (12) vorgesehen, der im montierten Zustand der Vorrichtung (1) an einer Innenseite des ringförmigen Rahmens (3) des Trampolins (2) anliegt und am Gehäuse (6) befestigt ist.
Patent EP-3955855-A1 (EP)
Inventor: ANDERSON EDWARD J
IPC: A61F2/24
Filed: 2020-04-16
Abstract: Disclosed herein are various embodiments of cardiac anchors configured to be inserted into a heart wall of a patient to anchor a suture as an artificial chordae under an appropriate tension for proper valve function. Such cardiac anchors are particularly suitable for use in intravascular, transcatheter procedures.
Patent EP-4051542-A1 (EP)
Title: Lining a roof structure of a driver's cab of a commercial vehicle
Inventor: SCHMITZ ANDREAS
IPC: B60R13/02
Filed: 2020-10-26
Abstract: The invention relates, inter alia, to a method for lining a roof structure (40) of a driver's cab of a commercial vehicle. The method involves suspending a lining part (10) in at least one sliding guide (46, 48) of the roof structure (40). The method involves moving the suspended lining part (10) along the at least one sliding guide (46, 48) to a target fitting position. The method involves attaching the lining part (10) to the roof structure (40) in the target fitting position. Thus the method can enable ergonomic fitting of the lining part (10) to the roof structure (40).
Patent EP-4042117-A1 (EP)
Inventor: FEUERSTEIN BERTRAM
IPC: G01J1/42
Filed: 2020-10-08
Abstract: L'invention concerne un dispositif. Le dispositif (110) comprend - au moins un photoconducteur (112) conçu pour présenter une résistance électrique dépendant d'un éclairage d'une région sensible à la lumière du photoconducteur (112) ; - au moins un circuit de lecture de photoconducteur (116), le circuit de lecture de photoconducteur (116) comprenant au moins un circuit diviseur de tension (118), le circuit diviseur de tension (118) comprenant au moins une résistance de référence Rref (120) agencée en série avec le photoconducteur (112), le circuit de lecture de photoconducteur (116) comprenant au moins un dispositif amplificateur (128), le circuit de lecture de photoconducteur (116) comprenant au moins un condensateur (126) agencé entre une entrée du dispositif amplificateur (128) et une sortie du circuit diviseur de tension (118).
Patent EP-4051587-A1 (EP)
Inventor: WILLS PAUL JOHN
IPC: B64D11/06
Filed: 2020-10-29
Abstract: The present invention provides an aircraft passenger accommodation unit (100) comprising a seat (110), a shell (120, 123) that allows a passenger egress between an aisle (11) and the seat through an opening (124), and a door assembly (140, 150, 160, 170, 180) comprising a door (141) slidable with respect to the shell between a retracted position (142) and an extended (143) position, a slide track (171) attached to the shell, a slide runner (151, 152) for sliding along the slide track, and a connection mechanism (181, 182) for selectively connecting the door to the slide runner, wherein the door has a first sliding mode in which the connection mechanism connects the door to the slide runner and wherein the slide runner slides along the slide track, and a second sliding mode in which the connection mechanism does not connect the door to the slide runner and wherein the door slides in relation to the slide track. The invention also provides a door arrangement and associated methods.
Patent EP-4052250-A1 (EP)
Inventor: CARUEL PIERRE
IPC: B32B3/12
Filed: 2020-10-28
Abstract: The present invention relates to an acoustic attenuation panel (1) comprising: - a cellular structure (10) comprising a plurality of acoustic cells (100) separated from one another by peripheral partitions (102), - a perforated acoustic structure (20), the perforated acoustic structure (20) and the cellular structure (10) being formed in one piece in a first material, and - a porous acoustic layer (30) formed of a second material and fastened to a surface of the perforated acoustic structure (20) by infixing at least one of the materials into a second material.
Patent EP-4062042-A1 (EP)
Inventor: ELLBRANT LARS
IPC: F01D9/02
Filed: 2020-11-19
Abstract: The present invention relates to a front centre body (FCB) structure for a geared turbofan engine. The FCB comprises a plurality of vanes extending across the inlet duct to the low pressure compressor and integrates a heat exchanging arrangement to control the temperature of the gearbox of the turbofan engine.
Patent EP-4073604-A1 (EP)
Title: Procédé de détermination d'au moins une valeur limite de marge de tolérance pour une variable technique à tester et dispositif de calcul correspondant
Inventor: KNICKER FLORIAN
IPC: G05B19/418
Filed: 2020-11-30
Abstract: L'invention concerne un procédé de détermination d'au moins une valeur limite de marge de tolérance (k, k p , k c ) pour une variable technique (x) à tester, consistant à : - obtenir (S10, S10p, S10c, S20) la ou les valeurs limites de marge de tolérance (k, k p , k c ) à partir de valeurs limites de marge de tolérance d'échantillon de différents échantillons, les échantillons comprenant des valeurs (z) de la variable technique (x) à tester de l'échantillon associé, l'obtention de la ou des valeurs limites de marge de tolérance (k, k p , k c ) comprenant l'utilisation d'une mesure de localisation (k moyen, k p  moyen, k c  moyen) d'une distribution selon laquelle sont distribuées les valeurs limites de marge de tolérance d'échantillon (k, k p , k c ), la variable technique (x) à tester étant distribuée selon une fonction de distribution de valeur extrême sous-jacente (F0, F9, F10), chacune des valeurs limites de marge de tolérance d'échantillon (k, k p , k c ) pouvant être ou étant calculée (S6, S6p, S6c) à l'aide d'une fonction de distribution de probabilité conditionnelle spécifique à un échantillon (F4, F11) qui est une fonction de valeurs d'échantillon (z) de l'échantillon, et la variable technique (x) se rapportant à une caractéristique physique d'un produit qui peut être produit dans le cadre d'un procédé industriel de production de masse.
Patent EP-3977112-A1 (EP)
Title: Mass spectrometry assay methods for detection of metabolites
Inventor: ROBINSON RICHARD J
IPC: G01N30/02
Filed: 2020-05-08
Abstract: A method for determining in a sample, by liquid chromatography/mass spectrometry, the presence, absence, or amount of one or more or a plurality of analytes selected. The method comprises subjecting the sample to an ionization source under conditions suitable to produce one or more ions detectable by mass spectrometry from each of the one or more of the analytes; measuring, by liquid chromatography/mass spectrometry, the amount of the one or more ions from each of the one or more analytes; and using the measured amount of the one or more ions to determine the presence, absence, or amount of each of the one or more or plurality of analytes in the sample.
Patent EP-3972221-A1 (EP)
Title: Ethernet data transmission method and communication device
Inventor: SUN DESHENG
IPC: H04L29/08
Filed: 2020-05-26
Abstract: This application provides an Ethernet data transmission method, including: sending, by a first device, a first bit stream to a second device, where the first bit stream is sent over N logical lanes of a physical layer of the first device; sending, by the first device, a first trigger marker group to the second device, where the first trigger marker group is used to indicate that the sending of the first bit stream ends; and sending, by the first device, a second bit stream to the second device in response to the sending of the first trigger marker group, where the second bit stream is sent over P logical lanes of the physical layer of the first device, and both N and P are positive integers.
Patent EP-3982917-A1 (EP)
Title: Compositions de soins bucco-dentaires sans rinçage
Inventor: STRAND ROSS
IPC: A61K8/44
Filed: 2020-06-11
Abstract: L'invention concerne une composition de soins bucco-dentaires sans rinçage pour favoriser la santé des gencives, ladite composition comprenant un acide hyaluronique et un polyol renforçant les gencives.
Patent EP-4065219-A1 (EP)
Inventor: MAURER JR CALVIN R
IPC: G06N3/08
Filed: 2020-11-18
Abstract: A method comprises identifying a treatment planning image of a target subject, the treatment planning image comprising information associated with an arrangement of structures within the target subject. The method further comprises generating, based on the information, a set of reference data associated with the target subject, the reference data indicating a plurality of positions of the target subject. The method further comprises generating target-subject-specific models based on the reference data and modifying one or more hyper-parameters of the target-subject-specific mode to generate second target-subject-specific models corresponding to a second position of the plurality of positions. The method further comprises controlling a radiation treatment delivery device based on the second target-subject-specific model to deliver a radiation treatment to the target subject.
Patent EP-3986767-A1 (EP)
Inventor: ZAMPINI DANIEL
IPC: B61L3/00
Filed: 2020-06-19
Abstract: The present disclosure includes a portable rail safety system configured to determine a position of a rail switch. The rail safety system may include a rail switch detector, one or more rail switch beacons, a work block marker, a personal alert device, a collision avoidance system or combination thereof. In some aspects rail switch detector includes a first detector configured to be positioned between switch rails of a rail track and having a body, a first sensor coupled to the body and configured to detect a first switch rail tip of the switch rails, and a controller configured to calculate a first distance between the first sensor and the first switch rail tip and based on the first distance, determine a position of the switch rails between a first position and a second position.
Patent EP-4085360-A1 (EP)
Inventor: RULE JEFFREY
IPC: G06F21/34
Filed: 2020-11-24
Abstract: Systems, methods, articles of manufacture, and computer-readable media for tapping a contactless card to a computing device to provision a virtual number. At least one parameter for authorizing a virtual account number for a subaccount associated with a primary account may be received. An application executing on a processor circuit may receive authentication credentials for the primary account. A card reader may receive encrypted data from a communications interface of a contactless card. The application may transmit the encrypted data to an authentication server. The application may receive verification of the encrypted data from the authentication server. The application may provide the at least one parameter for authorizing the virtual account number and receive a virtual account number for the subaccount generated by a virtual card number server, the virtual account number restricted to a spending limit based on the amount parameter associated with the virtual account number.
Patent EP-3987340-A1 (EP)
Inventor: DANZIGER YOCHAY
IPC: G02B26/06
Filed: 2020-06-23
Abstract: A display system (500) for displaying an image to an eye of a user includes a light- guide optical element (FOE) (506) and an image projector (512) projecting image illumination of a collimated image into the FOE. The image projector includes an electrically-controllable variable lens (10, 13, 71, 77, 58A, 58B, 59, 58C, 58D, 58E, 58F1, 58F2, 58G1, 58G2, 58H, 1223). A controller (18) determines a current region of interest of the image, either from tracking of the user's eye or by analysis of the image content, and controls the variable lens so as to reduce aberrations in the current region of interest at the expense of increased aberration in at least one area of the image outside the current region of interest.