baber/WOPTO huggingface dataset:
Patent NZ-241384-A (NZ)
Title: A mixture of 1s-cis-s, 1r-cis-s, 1s-trans-s and 1r-trans-s isomers of cypermethrin and insecticidal compositions
Inventor: BAUM JONATHAN SHEFFIELD
IPC: C07C255/39
Filed: 1992-01-23
Abstract: The four isomer compound derived from racemic cis/trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid and (S)(cyano)(3-phenoxyphenyl) methanol is twice as effective as cypermethrin against certain insect species, but quite unexpectedly is significantly less toxic to mammals and certain species of fish at rates giving commercial control of target crop insects.
Patent NZ-244892-A (NZ)
Title: 6-(1h-imidazol-1-ylmethyl)-2-phenylquinoline derivatives and pharmaceutical compositions
Inventor: CREMER GERARD
IPC: C07D215/12
Filed: 1992-10-27
Abstract: Compounds corresponding to the formula (I) <IMAGE>  in which,     R1 represents either a 1H-tetrazol-5-yl group or a CO2H group,   R2 represents either a (C1-7)alkyl group or a (C2-6)alkenyl group, R3 and R4 represent, each independently of the other, either a hydrogen atom, or a halogen atom, or a cyano group, or a (C1-7)alkyl group, or a (C3-7)cycloalkyl(C1-4)alkyl group, or an aryl group, or an aryl(C1-4)alkyl group, or an aryl(C2-4)alkenyl group, or a group -(CH2)mCOR5 in which m = 0 to 4 and R5 represents a hydrogen atom, an OH group, a (C1-6)alkoxy group or a group NR7R8, R7 and R8 representing, each independently of the other, a hydrogen atom or a (C1-4)alkyl group, or R3 and R4 represents, each independently of the other, a group -(CH2)n-R6 in which n = 1 to 4 and R6 represents an OH group, a (C1-6)alkoxy group, a (C1-4)alkoxy(C1-4)alkoxy group or a (C3-7)cycloalkyl(C1-4)alkoxy group,  and their pharmaceutically acceptable organic or inorganic salts. Application in therapeutics.
Patent NZ-245202-A (NZ)
Title: Particulate detergent containing ethoxylated c(8-18)primary alcohol, c(8-18)alkyl sulphate and zeolite; preparation
Inventor: AKKERMANS JOHANNES HENDRIKUS M
IPC: C11D3/12
Filed: 1992-11-20
Abstract: A particulate high-density detergent composition having excellent flow properties comprises 15 to 50 wt% of a high-performance surfactant system - selected ethoxylated alcohol nonionic surfactant plus optionally a minor amount of primary alkyl sulphate - and from 20 to 60 wt% of zeolite. The ethoxylated nonionic surfactant preferably has a peaked ethoxylation distribution, and the zeolite may advantageously be maximum aluminium zeolite P. The composition is preferably prepared by an agglomeration process utilising a high-speed mixer/granulator.
Patent NZ-245630-A (NZ)
Title: Use of rapamycin for manufacturing a medicament for treating or preventing hyperproliferative vascular disease
Inventor: MORRIS RANDALL ELLIS
IPC: C07D307/87
Filed: 1993-01-07
Abstract: This invention provides a method of preventing or treating hyperpoliferative vascular disease in a mammal by administering an antiproliferative effective amount of rapamycin alone or in combination with mycophenolic acid.
Patent NZ-255594-A (NZ)
Title: Hinged connector for panels comprises upper and lower profile parts with nested curved sections which interact with each other at a distance from pivot formations thereon
Inventor: OLSEN BJORN WILLY
IPC: E05D7/10
Filed: 1993-08-31
Abstract: PCT No. PCT/NO93/00131 Sec. 371 Date Apr. 6, 1995 Sec. 102(e) Date Apr. 6, 1995 PCT Filed Aug. 31, 1993 PCT Pub. No. WO94/05887 PCT Pub. Date Mar. 17, 1994An interconnecting element for connecting panels (2,23) consisting of upper (1) and lower (18) profile parts, the profile parts (1,18) having curved sections (5,20) which interact with each other at a distance from a pivotal joint (3). One side edge of the curved section (5) is intended to interact with the panel (2), and the other, opposite side edge is designed with a flange (4) which is at an angle to the pivotal joint (3) , which constitutes a rotation point for the curved section (5). Moreover the lower profile part (18) has a socket (19) for interaction with the pivotal joint (3), the curved section (20) being provided at a distance from the socket (19 ) for interaction with the upper profile part's curved section (5). The curved sections (5,20) are provided on the inside of the panels (2,23) on the end edges as an extension of the panels' (2,23) end profiles (10,30).
Patent NZ-260125-A (NZ)
Title: Compositions containing proliferation agent and transforming factor and methods for the repair of defects or lesions in cartilage
Inventor: HUNZIKER ERNST B
IPC: A61K45/08
Filed: 1992-01-28
Abstract: Methods and compositions are provided for the treatment and repair of defects or lesions in the cartilage of humans and other animals. The defect or lesion in the cartilage may be first treated with an enzyme to remove proteoglycans from the defect area. To induce cartilage formation, the defect is filled or otherwise dressed with a biodegradable matrix having pores sufficiently large to allow repair cells to populate the matrix. The matrix filling the defect contains a proliferation agent at a concentration sufficient to stimulate proliferation of repair cells and a transforming factor in an appropriate delivery system to release the transforming factor at a concentration sufficient to transform repair cells in the matrix and defect area into cartilage-producing chondrocytes. The matrix may also contain a chemotactic agent to attract repair cells. The entire treatment may be carried out in a single arthroscopic or open surgical procedure.
Patent NZ-260748-A (NZ)
Title: Water-dispersible tablet containing lamotrigine (3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine) and comprising water-swellable clay(s)
Inventor: FIELDEN KRYSTYNA ELZBIETA
IPC: A61K31/53
Filed: 1992-01-29
Abstract: A water-dispersible tablet is provided comprising 2% w/w to 90% w/w lamotrigine and 0.25 to 40% w/w of a pharmaceutically acceptable swellable clay which is present within the granules of the tablet. The tablet is capable of dispersing in water within a period of 3 minutes to provide a dispersion which is capable of passing through a sieve screen with a mesh aperture of 710 mu m in accordance with the test for dispersible tablet as defined in the British Pharmacopoeia 1988, volume II, page 895.
Patent NZ-261299-A (NZ)
Title: 9h-indeno[1,2-b]pyrazin-(di)ones and medicaments
Inventor: FAARUP PETER
IPC: A61P25/26
Filed: 1994-02-01
Abstract: The present invention relates to 9H-indeno[1,2-b]pyrazin-3(4H)-ones and 9H-indeno[1,2-b]pyrazine-2,3(1H,4H)-diones or tautomeric forms thereof which are useful in treating neurological and psychiatric diseases based on the antagonism of the glycine binding site on the NMDA receptor complex.
Patent NZ-264526-A (NZ)
Title: Solvent comprising a condensation product of an alkylene oxide having a low carboxylate anion content and use in stabilising anti cancer preparations containing teniposide, paclitaxel and camptothecin
Inventor: AGHARKAR SHREERHAM NARAHARI
IPC: A61K47/44
Filed: 1994-09-23
Abstract: A stabilized pharmaceutical composition containing paclitaxel, teniposide, camptothecin or other antineoplastic agent susceptible to degradation during storage is produced using a solvent system containing a low carboxylate anion content. The solvent system is a mixture of ethanol and a polyoxyethylated castor oil. The polyoxyethylated castor oil is treated with an acid or contacted with alumina to reduce the carboxylate anion content of the solvent. The low carboxylate anion content of the solvent provides extended shelf life and lower amounts of degradation by-products.
Patent NZ-274524-A (NZ)
Title: Peptides therapeutically active in the blood coagulation cascade
Inventor: FAUCHERE JEAN-LUC
IPC: A61P7/02
Filed: 1994-10-06
Abstract: PCT No. PCT/FR94/01166 Sec. 371 Date Apr. 2, 1996 Sec. 102(e) Date Apr. 2, 1996 PCT Filed Oct. 6, 1994 PCT Pub. No. WO95/09869 PCT Pub. Date Apr. 13, 1995The invention relates to the compounds of formula (I) (SEQ ID NO: I:H-phe-A1-Arg-Pro-(Gly)4-Asn-Gly-Asp-Phe-Glu-Abo-Ile-Pro-Glu-Glu-A2-Leu-glu-OH(I)in which A1 and A2 are as defined in the description. Medicinal products containing the same are useful as anticoagulants.
Patent NZ-305083-A (NZ)
Title: Use of cd40 binding proteins (a cd40 ligand or monoclonal antibody that specifically binds to cd40) for stimulating a immune response
Inventor: ALDERSON MARK
IPC: A61P31/04
Filed: 1996-02-29
Abstract: There is disclosed a method of stimulating an immune response comprising administering an effective amount of a CD40 binding protein. The method is useful in treating individuals infected with pathogenic or opportunistic organisms, and individuals having a depressed cellular immune response. CD40 binding proteins include CD40 ligand, monoclonal antibodies that specifically bind CD40, and combinations thereof.
Patent NZ-306782-A (NZ)
Title: A process for purifying correctly folded monomeric insulin-like growth factor-1 (igf-1)
Inventor: BRIERLEY RUSSELL A
IPC: C12P21/00
Filed: 1996-04-12
Abstract: Disclosed is an improved process for obtaining purified, monomeric, intact, correctly-folded insulin-like growth factor-I (also known as somatomedin-C). The improvements, consisting primarily of the addition of an IGF-I unfolding/refolding step and the substitution of a reverse phase chromatography step for a gel filtration chromatography step result in a three-fold increase in final yield. The process includes the following steps, in order: first cation exchange, unfolding/refolding, hydrophobic interaction chromatography, second cation exchange, and reverse phase chromatography.
Patent NZ-321646-A (NZ)
Title: Methods of capture and assay procedures
Inventor: PARTON ADRIAN
IPC: G01N33/543
Filed: 1996-11-08
Abstract: Methods of capturing and labelling a species, comprise attracting magnetically attractable particles to a solid support by magnetic forces, which particles have an affinity for said species, contacting said particles on said support with a sample containing said species to capture said species onto said particles on said support, and binding said species captured on said particles directly or indirectly to a detectable label before and/or whilst said species is captured on said particles on said support. The label may be bound to said captured species via an immunological binding partner which binds selectively to said species and may be a fluorescent label, luminescent label, enzyme label, dye label, phosphorescent label, metal-chelating label, radio label, spin label, heavy metal label, nucleic acid or nucleic acid analogue hybridisation label, avidin or avidin-like label suitably bound to or incorporated in particles which also bear a binding agent such as an antibody causing said particles to bind to the said captured species.
Patent NZ-321863-A (NZ)
Title: Personal cleansing composition comprising, surfactants, a hydrophobic active component, a hydrogen containing component and a cationic polymer
Inventor: CHOPRA SUMAN K
IPC: A61Q5/00
Filed: 1996-10-31
Abstract: A personal cleansing composition which comprisesa. a skin cleansing effective amount of a surfactant or mixture of surfactants,b. a hydrophobic active component in quantities which brings about a perceived effect on the skin, said effect selected from the group consisting of skin conditioning, skin protection from irritants and antibacterial agents,c. a hydrocarbon containing component, andd. a cationic polymerthe quantities of c and d selected so that the effect on the skin by component b is enhanced over the additive effects of c and d alone.
Patent NZ-329264-A (NZ)
Title: N-sulphonylbenzopyran-2-carboxamides and use in the treatment of diabetes
Inventor: MULLER TIMOTHEE
IPC: C07D311/72
Filed: 1997-11-26
Abstract: Benzopyran derivatives of formula (I) and their isomers and addition salts are new: R1 = 1-9C alkyl; R2, R4, R5 = H or 1-9C alkyl; R3 = H, 1-9C alkyl, 1-9C acyl, carboxy-1-9C alkyl, 2-10C alkoxycarbonyl or quinolinyl-2-methyl (optionally substituted in position 7 by halo); X = CO or CH2; Y = H, 1-9C alkyl or optionally substituted aryl; A = a bond; and R6 = 1-9C alkyl (optionally substituted by optionally substituted aryl) or optionally substituted aryl; or A = 1-9C alkylphenyl (optionally ring substituted), the alkyl group being attached to NY; and R6 = isocyanate, amino (optionally substituted by 1-2 1-9C alkyl or 2-10C alkoxycarbonyl) or NHCONHR7; R7 = optionally substituted Ph, 5-8C cycloalkyl (optionally substituted by 1-9C alkyl) or a 3-azabicyclo(3.3.0)octyl; optionally substituted aryl = Ph or naphthyl (optionally substituted by 1-3 1-9C alkyl, 1-9C alkoxy, 2-10C alkoxycarbonyl, COOH, 2-10C carboxyalkyl, 1-9C acyl, 2-10C alkylcarbonylamino, 1-9C aminoalkyl, amino (optionally substituted by 1-2 1-9C alkyl), 1-9C alkenyl, NO2, halo, trihalomethyl, phthalimido-1-9C alkyl or a group of formula (a); n = 1-6.
Patent NZ-330385-A (NZ)
Title: Pavers with horizontal ribs on edge faces
Inventor: JOUBERT FRANS JACOBUS
IPC: E01C5/00
Filed: 1998-05-07
Abstract: A paving block 10 has two nibs 2, 3 on opposite edge faces adjacent one end of the face.  A third nib 4 is provided centrally on another end edge face 6.  The nibs have their longitudinal axes parallel to the top surface of the block.  This facilitates the moulding of the blocks on-end.  The nibs ensure that a space is left between the blocks when laid to allow sand to pass between them.
Patent NZ-336188-A (NZ)
Title: Stable liquid mineral ascorbate compositions and methods of manufacture and use
Inventor: HEGENAUER JOHN C
IPC: A23L33/15
Filed: 1999-02-05
Abstract: Liquid vitamin C concentrate compositions comprise a mineral ascorbate and a pharmacologically acceptable liquid organic polyol solvent for the mineral ascorbate, the concentrate having a pH between about 5 and 7. The concentrate may also contain an aldonic compound and/or a pharmacologically acceptable zinc compound. The concentrate compositions are prepared by heating the solvent at 50-90oC and mixing the ascorbate and/or aldonic compound and/or zinc compound into the heated solvent, preferably in the absence of oxygen. The concentrate compositions are also characterized as a composition which comprises the reaction product of a mineral ascorbate and a pharmacologically acceptable liquid organic polyol solvent and, optionally, an aldonic compound and/or a soluble non-toxic zinc compound, which reaction product includes 4-hydroxy-5-methyl-3(2H)-furanone and/or 3-hydroxy kojic acid. Finished vitamin C products, characterized by excellent long term vitamin C stability, are conveniently prepared by incorporating the concentrates into finished cosmetic, medical and food products.
Patent NZ-503018-A (NZ)
Title: Chimaeric adenoviruses with reduced antigenicity
Inventor: VOGELS RONALD
IPC: C12N1/21
Filed: 1999-07-08
Abstract: A chimeric adenovirus comprising at least part of a fibre protein of an adenovirus serotype of subgroup B providing the chimeric virus with a desired host range and at least part of a penton or hexon protein or both, from another adenovirus serotype, selected for its immunogenic properties.
Patent NZ-507019-A (NZ)
Title: A leg rest assembly
Inventor: LAPOINTE LARRY P
IPC: A47C1/0355
Filed: 1997-08-06
Abstract: A leg rest assembly (28) for use with an article of furniture having a seat assembly supported from a frame assembly and an actuation mechanism (16) for enabling leg rest assembly (28) to move between a stowed position and an extended position, comprises a drive link (80) operably coupled to actuation mechanism (16) for rotation and a swing link bracket (84) operably coupled to the frame assembly for rotation.  A swing link arm (86) is releasably secured to swing link bracket (84) and defines a two-piece swing link assembly.  A pantograph linkage (30) is inter-disposed between a leg rest panel (34) and actuation mechanism (16) and is supported by the swing link assembly for coordinated articulated movement between the stowed position and the extended position.  Pantograph linkage (30) includes a support link (26) releasably secured to drive link (80) whereby pantograph linkage (30) is readily removable from the frame
Patent NZ-508544-A (NZ)
Title: Angiotensin converting enzyme inhibitors, such as quinapril, enalapril and indolapril, stabilised with 1-90 wt% magnesium oxide
Inventor: DANIEL JANE ELLEN
IPC: A61K47/02
Filed: 1999-05-10
Abstract: Describes a method directed to ACE inhibitor-containing compositions stabilized by the presence of magnesium oxide. Preferably, the ACE inhibitor, quinapril, is protected from certain forms of degradation when prepared in a pharmaceutical composition consisting essentially of magnesium oxide as the stabilizing agent. The presence of magnesium oxide also lends itself to favorable processing conditions during the manufacture of ACE inhibitor-containing compositions, especially processing by wet granulation.
Patent NZ-520619-A (NZ)
Title: Endolumenal device for delivering and deploying an endolumenal expandable prosthesis
Inventor: LOALDI ALESSANDRO
IPC: A61F2/958
Filed: 2000-12-19
Abstract: An endolumenal device (1) for delivering and deploying an endolumenal expandable prosthesis (6) at a bifurcation provided with a main conduit and at least a secondary conduit, comprises an elongated body (2) having a proximal end portion (4) and a distal end portion (3); the distal end portion (3) comprising expansion means (5) having a longitudinally extended active portion removably engageable with the prosthesis (6). The active portion of the expansion means is longitudinally associated to the body in order to expand the prosthesis eccentrically from one side with respect to the body, in order to leave free from the expanded active portion the other side of the body. The device further is provided with guidewire tracking means (11).
Patent NZ-522222-A (NZ)
Title: Valve assembly with closure element rotatable about axis coplanar and normal to axis of passage to provide smooth passage inner surface during opening
Inventor: GOSIS ANATOLY
IPC: F16K5/04
Filed: 2002-10-24
Abstract: A valve assembly (20) including a valve body (22) having an elongated passage (36) through which product flows and a valve element (24) which rotates about an axis (48) extending generally normal to an axis (38) defined by the passage (36) in the valve body (22) is disclosed. The valve element (24) is mounted in the valve body passage (36) to control product flow through the passage (36) as a function of the position of the valve element (24). The diameter of a valve body bore (47) within which the valve element (24) rotates is equal to or greater than the passage (36) it seals. A seal structure (60) cooperates with the valve element (24) to selectively seal the passage (36).
Patent NZ-524836-A (NZ)
Title: Shark meat extract capable of inhibiting angiogenesis and process for obtaining the extract
Inventor: DAVIS PAUL FRANK
IPC: A61K35/56
Filed: 2001-12-18
Abstract: An extract obtained from shark meat which his capable of inhibiting angiogenesis in an animal is described. A process for obtaining an angiogenesis inhibiting extract from shark meat comprises contacting meat from one or more sharks with a solvent, separating the meat from the solution and then removing the solvent from the solution to give and extract which is an inhibitor of angiogenesis. The extract can be used in the manufacture of a medicament for the treatment or prevention of diseases or disorders particularly cancer, retinopathy, inflammation and arthritis.
Patent NZ-526978-A (NZ)
Title: Inhibitors of papilloma virus
Inventor: YOAKIM CHRISTIANE
IPC: C07D407/10
Filed: 2001-12-14
Abstract: A compound of formula (I) or its enantiomers or diastereoisomers thereof: wherein: A is a 5- or 6-membered homocyclic ring, or a 5- or 6-membered heterocyclic ring containing 1 or more heteroatoms; X is H and W is OH; or X and W together form a carbonyl group or an epoxide; R1 is H; or one or two substituents; Y is phenyl optionally mono- or di-substituted, said phenyl ring being optionally fused with a saturated or unsaturated 4 to 6-membered ring optionally containing a heteroatom; or Y is a heterocycle (Het) containing one or more heteroatoms, said Het optionally mono- or di-substituted, said Het being optionally fused with a saturated or unsaturated 4 to 6-membered ring optionally containing a heteroatom; or Y is ethylene-phenyl, said ethylene moiety being optionally mono-substituted, wherein said phenyl ring is optionally mono- or di-substituted, said phenyl ring being optionally fused with a saturated or unsaturated 4 to 6-membered ring optionally containing a heteroatom; or Y is ethylene-Het, said ethylene moiety being optionally mono-substituted, wherein Het is optionally mono- or di-substituted; said Het being optionally fused with a saturated or unsaturated 4 to 6-membered ring optionally containing a heteroatom; R3 is selected from the group consisting of: lower alkyl, lower cycloalkyl, lower alkylene, aryl or lower aralkyl, all of which optionally mono- or di-substituted, said lower cycloalkyl, aryl, lower aralkyl or Het being optionally fused with a saturated or unsaturated 4 to 6-membered ring optionally containing a heteroatom; and R4 is a carboxylic acid, a salt or an ester thereof. The compounds may be used as inhibitors of the papilloma virus E1-E2-DNA complex.
Patent NZ-531002-A (NZ)
Title: An electrical connection device to groups of strands of a multi-bunch core of a machine, reeling or trailing cable
Inventor: WELLS MARK
IPC: H01R9/03
Filed: 2002-08-08
Abstract: An electrical connection device comprising a pin, socket or lug which is electrically connected to groups of strands of an individual multi-bunch core of a coaxial machine, reeling or trailing cable. The connection system consists of a series of concentric grooves or bores, the centre groove being a round hole to receive the central single bunch of wires, and each other groove being arranged annularly concentric with the central hole and longitudinally displaced from the previous groove, corresponding to one coaxial group of bunches of wires, and arranged to receive that group of bunches of wires. Retention of the wires and electrical conduction between the wires and the device are achieved preferably by crimping the outer part of each groove to crush the wires, or alternatively by soldering or welding.
Patent NZ-532858-A (NZ)
Title: Support device
Inventor: O'CONNOR RAYMOND EDWARD
IPC: A01J7/00
Filed: 2004-05-11
Abstract: A support device for use in a milking shed comprises a rail which supports downwardly depending arms and provides for longitudinal movement of the arms along the rail. The arms include locating means to position one or more conduits such that movement of an arm along the rail will move conduits supported on that arm.
Patent NZ-540140-A (NZ)
Title: A platform
Inventor: OETLLI PHILLIP GORDON
Filed: 2005-05-19
Abstract: A milking shed comprising a first stage formed of sufficient dimensions to enable a plurality of cows to stand thereon in formation, a second stage formed of sufficient dimensions to enable a plurality of cows to stand thereon in formation, a pit between the two stages, and a platform which can move between a stowed position and an operational position, the platform in an operation position providing a bridge over at least part of the floor of the pit between the two stages to enable an operator to stand thereon and readily access cows which are standing on at least one of the stages. The platform has a first part arranged for pivotal movement at or adjacent one side of the pit between the stowed and operational positions, and a second part arranged at or adjacent an opposite side of the pit for pivotal movement between the stowed and operational positions.