baber/WOPTO huggingface dataset:
Patent AU-710782-B2 (AU)
Title: Passive internal references for the detection of nucleic acid amplification products
Inventor: LIVAK KENNETH J
IPC: C12Q1/68
Filed: 1997-06-03
Granted: 1999-09-30
Abstract: The invention relates to passive internal references for use in quantitating the formation of amplification products in a nucleic amplification reaction. The internal amplification reference molecules of the invention comprise a first and second fluorophore joined together through a backbone connector. The first and second fluorophores are joined on the backbone in a configuration that permits the energy transfer from the first fluorophore to the second fluorophore. The backbone connector is selected so as not to bind to the target nucleic acid sequence under nucleic acid amplification conditions. Preferably, the backbone connector is a polynucleotide. Another aspect of the invention is to provide passive internal reference molecule containing reagent compositions for use in nucleic acid amplification reactions. The compositions comprise the internal amplification reference molecule of the invention and a nucleic acid amplification reaction buffer. The reagent compositions, optionally, include additional components required for nucleic acid amplification reactions. The invention also provides improved methods of measuring the amount of amplification product in nucleic acid amplification reactions employing fluorescer-quencher probe assays, including methods for the real-time measurement of amplification product formation. The methods comprise the step of adding the internal reference molecule of the invention to the amplification reaction mixture. Fluorescence of the second fluorophore on the internal reference may then be measured and used to calculate changes in fluorescence of the fluorophore on a fluorescer-quencher probe.
Patent AU-614627-B2 (AU)
Title: Electrically conductive microemulsions of the water in oil type based on perfluorinated compounds and used as a catholyte in electrochemical processes
Inventor: CHITTOFRATI ALBA
IPC: C08L71/00
Filed: 1989-06-14
Granted: 1991-09-05
Abstract: An electrochemical process is described wherein a gaseous substance is reduced at the cathode and in which microemulsions of the water-in-oil (w/o) type are utilized as catholytes, said microemulsions showing electric ion transfer and interphase matter transfer capacity. The oil phase of said microemulsion consists of perfluoropolyethers having perfluoroalkyl end groups or hydrophilic functional end groups or of perfluorocarbons and said microemulsions are obtained by using perfluorinated surfactants, in particular those having a perfluoroalkylpolyether structure and/or by using an alcohol as cosurfactant.
Patent AU-555548-B2 (AU)
Title: Low-trans fats and oil and water emulsion spreads containing such fats
Inventor: SCHMIDT WERNER JOHANNES
IPC: C11C3/10
Filed: 1985-01-29
Granted: 1986-10-02
Abstract: A fat blend having a relatively low level of trans fatty adds, which is preferably lower than 10% is obtained by random interesterification of lauric fats, saturated fats and a minor proportion of partially hydrogenated fats. A good melting behaviour in the mouth is achieved without recourse to fractionation.
Patent AU-762883-B2 (AU)
Title: Connecting apparatus using shape-memory technology
Inventor: JUSTIS JEFF R
IPC: A61B17/70
Filed: 2000-03-22
Granted: 2003-07-10
Abstract: An apparatus for connecting two members uses shape-memory technology. The connecting apparatus includes a first module having a connector portion adapted for connection to a first member, and a second module having a connector portion adapted for connection to a second member. Each module has a pair of flanges extending therefrom which are disposed about and overlap a portion of the connector portion of the other module. In one embodiment, a compression member at least partially formed of a shape-memory material is disposed adjacent to the flanges and has a first configuration at one temperature which allows relative movement between the modules, and a second configuration at a different temperature which limits relative movement between the modules. In another embodiment, each pair of flanges is at least partially formed of a shape-memory material and has a first configuration at one temperature which allows relative movement between the modules, and a second configuration at a different temperature which limits relative movement between the modules.
Patent AU-661160-B2 (AU)
Title: A beverage package and a method of packaging a beverage
Inventor: LYNCH FRANCIS JOSEPH
IPC: B65D79/00
Filed: 1993-06-24
Granted: 1995-07-13
Abstract: A beverage package and a method of packaging a beverage such as beer containing gas in solution has a container can 1 having a primary chamber 1A charged with beer 14 to form a small headspace 15. The can 1 is sealed and includes a submerged insert 8 forming a relief chamber 6 which is sealed by a closure 11. The insert 8 is responsive to heat applied during pasteurisation which causes the closure 11 to open the relief chamber so that the latter can accommodate beer derived from the primary chamber 1A to provide an enlarged headspace 15A. The small headspace 15 initially provided facilitates removal of air therefrom prior to sealing of the container while the enlarged headspace 15A is adequate to accommodate froth or foam developed by the intentional liberation of gas from solution in the beer. An insert part 7 forming a secondary chamber 5 may be provided for injecting gas or liquid into the beer to liberate gas therefrom for froth or foam development in the enlarged headspace. The relief chamber 6 may contain gas under pressure so that when opened to the primary chamber the release of such gas pressurises the enlarged headspace 15A. The insert part 7 may be located within the relief chamber 6. <IMAGE>
Patent AU-753897-B2 (AU)
Title: Furopyridine derivatives and their therapeutical use
Inventor: DYKE HAZEL JOAN
IPC: A61P27/02
Filed: 1999-06-07
Granted: 2002-10-31
Abstract: The compound, according to formula (i)wherein X and Y are independently CH, N or N-oxide, provided that X and Y do not both represent CH;Z is CO or CS;R1 is alkyl, optionally substituted with one or more halogens; andR2, R3, R4 and R5 are each various organic groups.Such compounds have therapeutic utility, via inhibition of phosphodiesterase IV.
Patent AU-614474-B2 (AU)
Title: Process for preparing 5-substituted-3-furaldehydes
Inventor: LEE GARY C M
IPC: C07F7/22
Filed: 1989-10-17
Granted: 1991-08-29
Abstract: The invention provides a process for preparing 5-substituted-3-furaldehydes which comprises reacting 3-furaldehyde with lithium morpholide, followed by sec-butyl lithium, followed by an electrophile.
Patent AU-707259-B2 (AU)
Title: Use of the hepatocyte growth factor to induce proliferation and differentiation of hemopoietic cells
Inventor: COMOGLIO PAOLO M
IPC: C12N5/0789
Filed: 1995-11-22
Granted: 1999-07-08
Abstract: PCT No. PCT/EP95/04589 Sec. 371 Date May 22, 1997 Sec. 102(e) Date May 22, 1997 PCT Filed Nov. 22, 1995 PCT Pub. No. WO96/15802 PCT Pub. Date May 30, 1996Hepatocyte growth factor stimulates proliferation and differentiation of hematopoietic cells, most preferably burst-forming unit-erythroid cells. The hepatocyte growth factor may be obtained from cells transformed with human gene sequences coding therefor. Pharmaceutical compositions useful to induce the proliferation and differentiation of hematopoietic cells may contain hepatocyte growth factor as an active principle in admixture with a suitable carrier. The pharmaceutical compositions may additionally contain stem cell factor as an active principle.
Patent AU-630131-B2 (AU)
Title: A power switching circuit, in particular for a frequency converter
Inventor: GOUSSET ALAIN
IPC: H03K17/08
Filed: 1989-11-22
Granted: 1992-10-22
Abstract: The present invention relates to a power interrupting device (T115, T5) comprising at least one power stage with bipolar transistor (T5) and one circuit for controlling this stage, the control circuit comprising first biasing means to apply a forward bias to the said stage during first time intervals (t3), and second polarising means to apply a reverse bias to the said stage, for second time intervals (t2, t4), and which is intended to prevent charges from accumulating in the transistor while it is exposed to a reverse voltage. 
<??>According to the invention, the first polarising means comprise a first capacitor (C108) and a first switching circuit (D120, T113) to selectively charge the first capacitor with the aid of a dc voltage source (Vp) outside the first time intervals and discharge the first capacitor into a control input (T115-G) of the said stage, and the second polarising means comprise a second capacitor (C107) and a second switching circuit (D119, D123, T113, T114) to selectively charge the second capacitor with the aid of the voltage source outside the second time intervals and discharge the second capacitor into the control input. 
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Patent AU-702557-B2 (AU)
Title: Novel protein and methods for producing the proteins
Inventor: GOTO MASAAKI
IPC: C12N1/21
Filed: 1996-02-20
Granted: 1999-02-25
Abstract: A protein which inhibits osteoclast differentiation and/or maturation and a method of production of the protein. The protein is produced by human embryonic lung fibroblasts and has molecular weight of about 60 kD and about 120 kD under non-reducing conditions and about 60 kD under reducing conditions on SDS-polyacrylamide gel electrophoresis, respectively.The protein can be isolated and purified from culture medium of the said fibroblasts. Furthermore, the protein can be produced by gene engineering.The present invention includes cDNA for producing the protein by gene engineering, antibodies having specific affinity to the protein or a method for determination of the protein concentration using the antibodies.
Patent AU-576650-B2 (AU)
Title: Transdermal drug patch containing water-swellable polymer
Inventor: CORDES GUNTER
IPC: A61L15/44
Filed: 1985-12-19
Granted: 1988-09-01
Abstract: The invention relates to transdermal drug patches for the controlled release of drugs to the human skin, comprising (a) an impermeable backing or covering layer, (b) a reservoir layer adjacent to, and in close contact with said backing or covering layer, said reservoir layer comprising a polymer matrix composed of a rubber and an adhesive resin material wherein said therapeutically active agent or agents are wholly or partially soluble and which is permeable to said agent or agents, (c) an adhesive layer adjacent to, and in close contact with, said reservoir layer and permeable to said therapeutically active agent or agents, and (d) a protective layer covering and adhearing to said adhesive layer and removeable therefrom for the use of said transdermal drug patch, the improvement wherein said drug or drugs in the rubber and adhesive resin material of the reservoir layer are present together with a polymer capable of swelling in water and insoluble in the rubber and adhesive resin material of the reservoir layer, the quantity of said polymer being between 3 and 30% by weight of the rubber and adhesive resin mixture. By the incorporation of this particular water-swellable polymer material in the rubber/adhesive resin mixture together with the drug which polymer material is insoluble in the matrix, in a particular proportion calculated to the weight of the rubber and adhesive resin material in particular the drug release from the patch to the skin is increased to twice or even more is achieved.
Patent AU-673558-B2 (AU)
Title: Shoe with central buckle
Inventor: HIEBLNGER RUDOLF
IPC: A43B5/00
Filed: 1993-11-02
Granted: 1996-11-14
Abstract: A shoe of the type having a sole and an upper formed of nonrigid materials attached to the sole, and with a central closure mechanism that is coupled with at least one elongated flexible tightening element by which a vamp of the upper can be tightened and loosened via increasing and decreasing an effective length of the at least one tightening element as measured from the central closure mechanism as it runs between guide elements on the upper and on an instep shield. In accordance with preferred embodiments, the shoe upper has a closed vamp, at least the instep area of which is formed of a volume-elastic compressible material and the instep cover is formed of an elastically bendable material at least approximately matched to the surface contour at least a portion of the instep. Additionally, the central closure is provided on the outside of the back of the upper above the heel, and the tightening element runs from the central closure along both sides of the shoe, via a guide element provided curving around the heel from near the height of the insole, without crossing the instep, to a higher guide element provided on the instep cover and then to a forward guide element lying at the level of the insole on the outside of the shoe upper near the small toe at the medial side of the shoe and in the area between the metatarsophalangeal joint of the big toe and approximately the center of the arch on the lateral side of the shoe.
Patent AU-759776-B2 (AU)
Title: An over-expressing homologous antigen vaccine and a method of making the same
Inventor: BOYLE STEPHEN M
IPC: C07K14/23
Filed: 1997-12-05
Granted: 2003-05-01
Abstract: This invention relates to an over-expressing homologous antigen vaccine, a method of producing the same, and use of the vaccine for prophylaxis or treatment of vertebrates at risk of or suffering from disease caused by a pathogenic micro-organism. The vaccine is an attenuated or avirulent pathogenic micro-organism that over-expresses at least one homologous antigen encoded by at least one gene derived from the pathogenic micro-organism, and may also express a heterologous antigen.
Patent AU-582647-B2 (AU)
Title: Fluid fuel combustion process and turbulent-flow burner for implementing same
Inventor: FLAMENT GERARD
IPC: F23C7/00
Filed: 1986-05-01
Granted: 1989-04-06
Abstract: In this combustion process a fluid fuel such as pulverized coal mixed with primary air is injected along an axis and secondary air is injected along a helical path around the axis. Tertiary air is injected around the combustible fluid and the secondary air in substantially the same direction as the combustible fluid, in a substantial circumferentially continuous coaxial ring which is laterally confined downstream of the injection point.
Patent AU-681109-B2 (AU)
Title: Energy-supplementing saccharide source and its uses
Inventor: SHIBUYA TAKASHI
IPC: A23L1/09
Filed: 1994-03-16
Granted: 1997-08-21
Abstract: Trehalose, prepared by the method containing a step of allowing a non-reducing saccharide-forming enzyme to act on a partial starch hydrolysate exhibiting a reducing power, is advantageously used as an energy-supplementing saccharide source and used in energy-supplementing compositions as an effective ingredient. The saccharide source and compositions can be suitably used as pharmaceutical compositions for supplementing energy for living bodies without a fear of causing side effects.
Patent AU-766195-B2 (AU)
Title: N-chlorosulfamate compositions having enhanced antimicrobial efficacy
Inventor: REES WAYNE M
IPC: A01N25/02
Filed: 2000-06-28
Granted: 2003-10-09
Abstract: The antimicrobial efficacy of N-chlorosulfamate solutions, namely buffered aqueous combinations of HClNSO3-(mono-N-chlorosulfamate) and Cl2NSO3 (di-N-chlorosulfamate), herein referred to as "stabilized hypochlorite", can be markedly enhanced by the addition of certain organic dopants. The dopants themselves are select hypochlorite stabilizing agents, which are known to readily form stable organochloramides when reacted with "free" hypochlorite (HOCl or NaOCl). Highly effective antimicrobial enhancing dopants include 5,5-dialkyl hydantoins, arylsulfonamides, and succinimides. Examples of these include 5,5-dimethylhydantoin, benzenesulfonamide, and succinimide. Other, less effective dopants include glycolurils. Generally, the dopant is present in a minor mole fraction, relative to the molar amount of stabilized hypochlorite present in the enhanced antimicrobial solution.
Patent AU-721079-B2 (AU)
Title: Peptidyl heterocycles useful in the treatment of thrombin related disorders
Inventor: COSTANZO MICHAEL J
IPC: C07K5/06
Filed: 1996-06-03
Granted: 2000-06-22
Abstract: Compounds of the Formula I:    <IMAGE>  I  useful in the treatment of thrombin and trypsin related disorders.
Patent AU-597596-B2 (AU)
Title: Washing machine drain
Inventor: ZINKANN PETER
IPC: D06F39/08
Filed: 1986-10-02
Granted: 1990-06-07
Abstract: PCT No. PCT/DE86/00400 Sec. 371 Date Jun. 3, 1987 Sec. 102(e) Date Jun. 3, 1987 PCT Filed Oct. 2, 1986 PCT Pub. No. WO87/02078 PCT Pub. Date Apr. 9, 1987.A washing machine which includes a wash tub for receiving water and articles to be washed, a drain connected to the wash tub, a float disposed within the drain, a drain water reservoir for receiving and storing water removed from the wash tub through the drain and for providing back pressure on the float, and a pump for pumping water from the wash tub, through the drain, and into the drain water reservoir.
Patent AU-681879-B2 (AU)
Title: Oesteoblast growth stimulating compostion containing PDGF and vitamin D
Inventor: MOORE EMMA E
IPC: A61K38/22
Filed: 1994-03-29
Granted: 1997-09-11
Abstract: Methods and compositions for stimulating the growth of osteoblasts are disclosed. A composition comprising platelet derived growth factor and vitamin D is applied to osteoblasts in an amount sufficient to stimulate their growth. The methods may be used to promote the growth of osteoblasts in vitro or to promote the healing of bone defects in vivo.
Patent AU-649925-B2 (AU)
Title: Extrusion die assembly
Inventor: FARNSWORTH JOHN T
IPC: B29C48/335
Filed: 1990-11-27
Granted: 1994-06-02
Abstract: A free-standing die assembly 10, for use in the production of extruded products, which is mounted as a separate unit apart from the extruder in which product ingredients are processed. The die assembly includes a center plate (17) having a die unit (23) secured to one or more planar faces of the plate, with each of the die units having at least one die orifice (35) in the outer surface thereof. Hot flowable dough processed in an extruder is carried via suitable tubing to the center plate from where it is distributed to the planar faces of the plate and into the die units, from which it is extruded through the die orifices in the die units. The die assembly may be modified to permit the production of coextruded product from the die orifices in the die units of the assembly. One or more of the die assemblies may be associated with a single extruder. In accordance with a preferred embodiment, die units are secured to opposing side faces of the center plate to provide a free standing, dual-faced die assembly. <IMAGE>
Patent AU-634620-B2 (AU)
Title: Polyvinyl acetate encapsulation of codried sucralose for use in chewing gum
IPC: A23L1/09
Filed: 1990-11-21
Granted: 1993-02-25
Abstract: A sucrose-containing chewing gum ingredient is prepared by mixing about 50 to about 95 parts by weight polyvinyl acetate with about 5 to about 50 parts by weight of a solution comprising sucralose dissolved in a solvent. The mixture is then dried to drive off the solvent. A chewing gum is prepared by mixing the sucralose-containing ingredient, gum base, a bulking agent and flavor to make a chewing gum composition.
Patent AU-703477-B2 (AU)
Title: Line marking shoe
Inventor: MCGUFFIE IAIN PETER
IPC: E01C23/20
Filed: 1996-09-20
Granted: 1999-03-25
Abstract: PCT No. PCT/GB96/02323 Sec. 371 Date Jun. 10, 1998 Sec. 102(e) Date Jun. 10, 1998 PCT Filed Sep. 20, 1996 PCT Pub. No. WO97/21871 PCT Pub. Date Jun. 19, 1997A line marking shoe (1) adapted in use to be advanced relative to a ground surface in a line marking direction to mark a line onto the ground surface in the line marking direction (A) includes a sole part (3) having a discharge opening region (13) formed in it for discharge of line marking material onto the ground surface The discharge opening region includes a number of discharge opening areas and the discharge opening areas are so dimensioned and arranged that discharge of line marking material onto the ground surface through different discharge opening areas produces lines of different widths on the ground surface.
Patent AU-675336-B2 (AU)
Title: Method and apparatus for controlling shift force in an automated mechanical transmission
Inventor: EDELEN STEPHEN ALTON
IPC: F16H61/32
Filed: 1994-08-09
Granted: 1997-01-30
Abstract: The shift quality of an automated mechanical transmission (10) is improved and transmission wear is reduced by controlling the armature current of the motor driving the transmission shifting mechanism (22). The current is monitored by a microcontroller (16) to determine if the shifting mechanism has encountered a snag or has stalled during a shift operation. The microcontroller (16) is programmed to control the duty cycle of a pulse width modulated (PWM) voltage signal, applied to the motor, in accordance with an algorithm which provides both proportional and derivative control of the error between the measured current and a target current. The rapid reduction in current spikes through PWM control reduces the force applied to the shifting mechanism (22) and thus the sliding clutch and transmission gearing. <IMAGE>
Patent AU-711453-B2 (AU)
Title: Cleaning and freshening unit intended for suspension from a rim of a toilet bowl
Inventor: LAMPE CAROLUS BENEDICTUS WILHE
IPC: E03D9/03
Filed: 1996-11-21
Granted: 1999-10-14
Abstract: A cleaning and freshening unit (1) provided with a holder (2) and a liquid reservoir (4) detachably connected to the holder (2), the unit being provided with means (5) for suspension from a rim of a toilet bowl, the unit (1) also being provided with a porous, liquid-absorbing mass (6) which always communicates with liquid (F) contained in the liquid reservoir (4), the holder (2) being provided with a connecting nipple (7) suitable for connection to a discharge opening (8) of the bottle (3), the discharge opening (8) of the bottle (3) when connected being partly closed by a closing wall (9) provided with at least one liquid passage opening (10) which opens into an inlet (11<a>) of a channel (11) abutting with an outlet (11<b>) having a limited surface against the porous mass (6), and provided with at least one air supply opening (12) communicating with the ambient pressure, the sizes of the liquid passage opening (10) and the air supply opening (12) being such that the liquid pressure on the porous mass (6) is always equal and independent of the liquid level in the liquid reservoir (4). <IMAGE>
Patent AU-540941-B2 (AU)
Title: Building block set
Inventor: LIN WEN-PING
IPC: A63H33/10
Filed: 1981-09-10
Granted: 1984-12-06
Abstract: A set of building blocks readily assembled to form a variety of houses comprises several flexible wall elements, flexible roof elements, roof forming elements, roof connecting elements, cubic elements, and base boards which can be connected side by side to construct a base as a ground member of the houses. The wall elements can be bent into different configurations so as to act as side walls at one's desire.