baber/WOPTO huggingface dataset:
Patent JP-2732546-B2 (JP)
IPC: A61P25/04
Filed: 1993-08-27
Granted: 1998-03-30
Abstract: Compositions and methods are provided for the treatment and diagnosis of diseases amenable to treatment through modulation of the synthesis or metabolism of intercellular adhesion molecules. In accordance with preferred embodiments, oligonucleotides are provided which are specifically hybridizable with nucleic acids encoding intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and endothelial leukocyte adhesion molecule-1. The oligonucleotide comprises nucleotide units sufficient in identity and number to effect said specific hybridization. In other preferred embodiments, the oligonucleotides are specifically hybridizable with a transcription initiation site, a translation initiation site, 5'-untranslated sequences, 3'-untranslated sequences, and intervening sequences. Methods of treating animals suffering from disease amenable to therapeutic intervention by modulating cell adhesion proteins with an oligonucleotide specifically hybridizable with RNA or DNA corresponding to one of the foregoing proteins are disclosed. Methods for treatment of diseases responding to modulation cell adhesion molecules are disclosed.
Patent JP-3048632-B2 (JP)
IPC: C07K16/00
Filed: 1990-05-30
Granted: 2000-06-05
Abstract: Monoclonal antibodies and method for ameliorating an immune response disorder. The monoclonal antibodies are specific for an epitope present on the leukocyte adhesion receptor beta-chain.
Patent JP-3473910-B2 (JP)
IPC: C08L101/16
Filed: 1993-10-06
Granted: 2003-12-08
Abstract: According to the present invention there is provided a composition as obtained from a melt comprising esterified starch, preferably having a degree of substitution of at least about 1.5, and preferably an amylose content of at least about 50% by weight with respect to that of the starch, and a linear polyester. The invention further provides the composition in the form of a melt or when shaped into articles.
Patent JP-3119870-B2 (JP)
IPC: H04Q7/22
Filed: 1991-07-01
Granted: 2000-12-25
Abstract: This invention relates to interfaces between facsimile machines and cellular telephone systems (including both cellular subscriber terminals and the fixed part of the system, such as the mobile switching center and the interworking function). The cellular radio telephone system could for example be GSM. To prevent two different facsimile machine timers (specified in the CCITT T.30 recommendation) from expiring during the communication between two such machines connected to the GSM environment, a timer reset command (e.g. a command repeat signal) is automatically sent by the interface (12 or 15) to the facsimile machine on receipt of the command from the facsimile machine, for causing the machine to repeat its command so as to allow time for receipt of a response from the other machine. Instead of sending this response only if a command is not recognized (as recommended in T.30), it is used as the default response whenever the GSM environment receives a command from a facsimile machine. If necessary this response can be used twice.
Patent JP-2917525-B2 (JP)
IPC: E01F9/619
Filed: 1996-12-18
Granted: 1999-07-12
Abstract: A COMPOSITE WITH A HYDROPHILIFIABLE SURFACE, COMPRISING, (A) A SUBSTRATE; AND (B) A LAYER PROVIDED ON THE SURFACE OF THE SUBSTRATE, THE LAYER CONTAINING A PHOTOCATALYTIC SEMICONDUCTOR MATERIAL, THE PHOTOCATALYTIC SEMICONDUCTOR MATERIAL OPERATING IN RESPONSE TO THE PHOTOEXCITATION THEREOF TO ENHANCE A HYDROGEN BOND COMPONENT (γSH) IN THE SURFACE ENERGY IN THE SOLID/GAS INTERFACE OF THE LAYER, THEREBY HYDROPHILIFYING THE SURFACE OF THE COMPOSITE. THE COMPOSIT DOES NOT UNDERGO ANY DEPISITION OF CONTAMINANTS ON THE SURFACE THEREOF AND IS READILY CLEANED BY RAINFALL OR WASHING WITH WATER.(FIG 7)
Patent JP-3143473-B2 (JP)
IPC: H01L21/321
Filed: 1991-11-18
Granted: 2001-03-07
Abstract: PCT No. PCT/GB91/02029 Sec. 371 Date May 11, 1993 Sec. 102(e) Date May 11, 1993 PCT Filed Nov. 18, 1991 PCT Pub. No. WO92/09104 PCT Pub. Date May 29, 1992.The invention provides a method of producing silicon-on-porous-silicon material comprising the steps of (i) manufacturing a porous silicon layer on a suitable silicon wafer, such that the silicon wafer has a porous silicon surface and a non-porous silicon surface, (ii) applying an implanted ion dose to at least a portion of the porous silicon surface such that the dose is sufficient to cause amorphization of porous silicon. The material produced by the method of the invention can then be used for production of silicon-on-insulator material by oxidation of remaining porous silicon and recrystallization of amorphised silicon. Typically such material can be used for manufacture of e.g. SOI C-MOS devices and bipolar transistors. Alternatively, the method of the invention can be used for the manufacture of e.g. pyroelectric devices.
Patent JP-3974168-B2 (JP)
IPC: C07K16/00
Filed: 1993-03-03
Granted: 2007-09-12
Abstract: Processing of  beta -amyloid precursor protein ( beta APP) is monitored by detecting the secretion of a soluble  beta APP fragment resulting from cleavage of  beta APP at the amino-terminus of  beta -amyloid peptide. In vivo monitoring of secretion of the  beta APP fragment may be monitored for diagnosis and prognosis of Alzheimer's disease and other  beta -amyloid-related diseases, while in vitro monitoring of such secretion from cultured cells may be monitored to identify inhibitors of  beta -amyloid production. The  beta APP fragment may be detected using antibodies and other specific binding substances which recognize a carboxy-terminal residue on the fragment.
Patent JP-3701978-B2 (JP)
IPC: A61B17/16
Filed: 1997-10-15
Granted: 2005-10-05
Abstract: An instrument and method for surgical stimulation of connective tissue are disclosed. The instrument has a plurality of protuberances located on a head connected to a shaft and a handle for manipulation by a surgeon to selectively perforate diseased connective tissue to stimulate a variety of desirable biological responses resulting from bleeding from the intrinsic vasculature of the connective tissue, investing tissue, and adjoining bone.
Patent ES-2364308-B2 (ES)
Title: Sistema de dimming pwm en serie a alta frefuencia para aplicación en convertidores de din�?mica lenta para l�?mparas de estado sólido.
Inventor: GACIO VAQUERO DAVID
IPC: H05B44/00
Filed: 2010-02-19
Granted: 2012-03-13
Abstract: Sistema de dimming PWM en serie a alta frecuencia para aplicación en convertidores de dinámica lenta para lámparas de estado sólido. sistema de dimming (o atenuación o regulación del flujo luminoso) PWM en serie a alta frecuencia, para aplicación en convertidores de dinámica lenta, incluso de una sola etapa con corrección de factor de potencia o convertidores CC/CC de dinámica lenta, para lámparas de estado sólido como por ejemplo LEDs OLEDs o PLEDs en el que el dimming en serie se realiza a una frecuencia comparable a la frecuencia de conmutación del convertidor. Se trata de un sistema electrónico para su aplicación en el sector de iluminación artificial.
Patent ES-2350675-B2 (ES)
Title: Estructuras dendriticas en base a tetraarilmetano.
Inventor: REGUEIRA MARIA
IPC: C07C15/54
Filed: 2010-09-10
Granted: 2011-09-08
Abstract: Estructuras dendríticas en base a
tetraarilmetano. La presente invención se refiere a dendrímeros de
fórmula I  constituidas por unidades tetraédricas con rigidez
radial de tetrafenilmetano de tipo AB_{3} enlazadas entre sí
mediante conectores lineales rígidos. 
     También se refiere a los dendrones de fórmula II
intermedios y a un procedimiento muy versátil para la preparación de
los dendrímeros de fórmula I.
Patent ES-2440391-B2 (ES)
Title: Método para operar una central eléctrica con múltiples fuentes térmicas y dispositivo empleado
Inventor: KRIEGER ZVI
IPC: F22B1/00
Filed: 2009-06-29
Granted: 2015-05-11
Abstract: Método para operar una central eléctrica con múltiples fuentes térmicas y dispositivo empleado, en donde se utiliza un fluido de una fuente térmica de baja-media temperatura, y en donde la central eléctrica con múltiples fuentes térmicas incluye una turbina o equipo de expansión que trabaja con un fluido motor orgánico, que comprende el precalentamiento del fluido motor orgánico usando el fluido de la fuente térmica de baja-media temperatura y además provee más calor desde una fuente térmica adicional para vaporizar el fluido motor que se suministra a la turbina o equipo de expansión. El dispositivo empleado comprende un intercambiador de calor adecuado para el precalentamiento de un fluido motor orgánico con un fluido geotérmico de baja-media temperatura, y medios de captación de energía solar adecuados para proporcionar calor directa o indirectamente al fluido motor orgánico precalentado para calentar o vaporizar el fluido motor.
Patent ES-2535556-B2 (ES)
Title: Procedimiento selectivo de extracción de metales de un mineral bruto, dispositivo y sistema para su realización
Inventor: LOPEZ BUENDIA ANGEL MIGUEL
IPC: H05B6/00
Filed: 2015-02-09
Granted: 2015-11-12
Abstract: La presente invención se refiere a un procedimiento selectivo de extracción de metales de un mineral bruto, que comprende el tratamiento de dicho mineral bruto con un campo magnético dominante de las microondas, o campo H, en aplicador monomodo abierto, y la separación de los productos obtenidos. El procedimiento permite operar en continuo. Para la realización del procedimiento la invención define un dispositivo de procesado de mineral bruto que comprende una cámara (1) para confinar microondas y seleccionar un modo de campo H, de campo E o de campo alternante E-H, de acuerdo con las propiedades de permitividad dieléctrica y permeabilidad magnética complejas del mineral bruto, medios de transporte (7, 8, 9) para transportar removiendo las partículas del mineral bruto a través de la cámara, medios de aplicación para generar un campo electromagnético de microondas en el interior de la cámara, y medios de sintonización (4) para sintonizar y adaptar la frecuencia del modo electromagnético.
Patent AU-2002244584-B2 (AU)
Title: Methods to culture circovirus
Inventor: WILLSON PHILIP
IPC: C12N5/02
Filed: 2002-03-27
Granted: 2006-12-14
Abstract: The present invention relates to methods for culturing circovirus and in particular, porcine circovirus. The present invention provides compositions and methods for culturing porcine circovirus in mammalian cells expressing mammalian adenovirus E1 function.
Patent AU-2003203534-B2 (AU)
Title: Dismountable casting mold side wall system
Inventor: VAPPULA KARI
IPC: B28B7/00
Filed: 2003-04-02
Granted: 2007-09-13
Abstract: Dismountable casting mold side wall system including a side wall (1) attachable dismountably to the casting mold and a magnet(2) adapted to clamp onto a casting bed so as attach said side wall (1) thereto, in which system the release/clamp operations of the magnet (2) are adapted to take place in the interior space remaining between the exterior sides of said side wall (1). <IMAGE>
Patent AU-2003238740-B2 (AU)
Title: Immunomodulatory constructs and their uses
Inventor: FRASER JOHN DAVID
IPC: A61K39/00
Filed: 2003-06-04
Granted: 2009-04-09
Abstract: The invention relates to immunomodulators. In particular the invention relates to specific immunomodulators based on the superantigen SMEZ-2 and more particularly based on mutants of the superantigen SMEZ-2, which are adapted to target antigen-presenting-cells for the purpose of enhancing or suppressing a host immune response.
Patent AU-2003249558-B2 (AU)
Title: A portable beverage preparation device and system
Inventor: LEVIN SHALOM
IPC: B65D51/28
Filed: 2003-08-07
Granted: 2010-03-11
Abstract: A portable beverage preparation device and system for making brews, mixes, and potions on demand by selectively introducing and mixing predetermined quantities of at least one stored, edible, beverage preparation confined in at least one sealed chamber into a portable beverage container containing a predetermined volume of a potable base liquid and having a dispenser means for introducing the at least one beverage preparation into the potable base liquid; wherein the drink container and the at least one sealed chamber are in close physical proximity to each other and separated by at least one thin membrane which, when inwardly perforated by the dispenser means, introduces the at least one beverage preparation into the base liquid. The system of the invention further provides a brewing element and a portable heating unit, the heater element of which fits into the beverage container for heating the liquid.
Patent AU-2003302882-B2 (AU)
Title: System for determining endothelial dependent vasoactivity
Inventor: AMITZUR GIORA
IPC: A61B5/366
Filed: 2003-12-03
Granted: 2008-06-19
Abstract: A method of determining endothelial dependent vasoactivity of a subject, the method is effected by recording pressure-related signals of a plurality of locations adjacent to at least one blood vessel; extracting at least one parameter from the pressure-related signals; and using the at least one parameter to determine a change of at least one characteristic of the at least one blood vessel, the change being representative of endothelial functioning; thereby determining the endothelial dependent vasoactivity of the subject.
Patent AU-2004220477-B2 (AU)
Title: 2-Substituted vitamin D analogues and their therapeutic uses
Inventor: CLERCQ PIERRE DE
IPC: A61P19/08
Filed: 2004-03-10
Granted: 2010-05-06
Abstract: The present invention relates to analogues of vitamin D namely 14-epi-2-alkyl-19-nor vitamin D derivatives. Also a general method for the synthesis and the biological activities are described. The general formula is: (I) where R (alpha or beta oriented) represents an alkyl substituent and X part of a typical side chain of vitamin D or of one of its established analogues.
Patent AU-2004220539-B2 (AU)
Title: Apparatus and process for dose-guided radiotherapy
Inventor: JUSTUS BRIAN L
IPC: A61N5/10
Filed: 2004-03-04
Granted: 2010-09-02
Abstract: A method and an apparatus for dose-guided radiotherapy for a patient (P) having an identified radiotherapy target utilizes a radiation detecting array (R) of radiation-sensitive dosimeters for the real-time remote measurement of radiotherapy at the radiation detecting array (R). The radiation detecting array is positioned within the patient's (P) body along the treatment path before or after the identified radiotherapy target or the device may be positioned beyond the patient (P) to measure transit dose. A radiation source (A) for emitting radiation for radiotherapy along a treatment path through the patient (P) to the identified radiotherapy target is utilized. The method includes generating a predicted dose pattern of radiation at the placed radiation detecting array (R). The predicted dose pattern assumes an on-target radiation source (A) emitting the radiotherapy beam along the treatment path through the patient (P) to the identified radiotherapy target. Gating of the radiation source (A) can occur responsive to the comparing of the predicted dose pattern of radiation to the real-time dose pattern at the radiation detecting array (R). Radiation intensity can vary between low levels to a treatment level responsive to coincidence of the predicted dose pattern of radiation to the real-time dose pattern at the radiation detecting array (R).
Patent AU-2004270699-B2 (AU)
Title: Heterocyclic inhibitors of MEK and methods of use thereof
Inventor: WOON YANG HOON
IPC: A61K31/42
Filed: 2004-09-01
Granted: 2011-11-10
Abstract: Disclosed are compounds of the Formula (I) and pharmaceutically acceptable salts and prodrugs thereof, wherein R, R, R, R, R and R, W and Y are defined in the specification. Such compounds are MEK inhibitors and useful in the treament of hyperproliferative diseases, such as cancer and inflammation, in mammals. Also disclosed are methods of using such compounds in the treatment of hyperproliferative disease in mammals and pharmaceutical compositons conataining such compounds.
Patent AU-2004282492-B2 (AU)
Title: Prevention of incorporation of non-standard amino acids into protein
Inventor: BOGOSIAN GREGG
IPC: C12P21/02
Filed: 2004-09-23
Granted: 2011-02-10
Abstract: The instant invention is drawn to the methods and compositions necessary to provide recombinant proteins with a substantially reduced or eliminated content of norleucine or other non-standard amino acids. Various embodiments of the invention provide for the substantial elimination of the incorporation of non-standard amino acids into recombinant proteins by the co-expression or enhanced expression of a protein (or the enzymatically active portion thereof) capable of degrading norleucine or other non-standard amino acids, including norvaline, betamethylnorleucine, and homoisoleucine. In certain particular embodiments of the invention, the norleucine is degraded by a glutamate dehydrogenase, a leucine dehydrogenase, a valine dehydrogenase, a phenylalanine dehydrogenase, a glutamate/leucine/phenylalanine/valine dehydrogenase, or an opine dehydrogenase. Also provided are the cells and DNA constructs for carrying out these methods.
Patent AU-2005200038-B2 (AU)
Title: Thermally insulated pipeline
Inventor: MICHALSKI PIERRE
IPC: F17D1/02
Filed: 2005-01-06
Granted: 2009-05-28
Abstract: The line has a heat insulation layer (2) surrounding a leak proof pipe (1) at the level of external surface of the pipe. A leak proof pipe (3) is disposed around the insulation layer coaxial to the pipe (1). A heat insulation layer (4) constituted of internal and external layers surrounds the pipe (3). The pipes are constituted of material which has high expansion coefficient, such as stainless steel. Independent claims are also included for the following: (A) a utilization of a line for the transportation of low temperature fluid (B) a maritime terminal for the transportation of liquefied gas.
Patent AU-2005203406-B2 (AU)
Title: Flow mixing machine and method according to a determined ratio of a biological fluid and a solution
Inventor: BEHAGUE MAURICE
IPC: A61M1/36
Filed: 2005-08-02
Granted: 2011-03-17
Abstract: The mixing machine has a device (7) such as a balance for measuring the volume of the biological fluid, especially blood, which is taken by a natural flow, a pump for an anticoagulant and/or preserving solution such as citrate phosphate dextrose, and a pump control unit (8). The control unit contains one device for determining the volume of the pumped solution and another for regulating the speed of the pump. According to the required biological fluid/solution ratio it calculates the theoretical volume of the solution to be mixed with the fluid drawn, compares the theoretical volume with the pumped volume of the solution, and adjusts the speed of the pump to give the required ratio.
Patent AU-2005242181-B2 (AU)
Title: Usage of air pulse techniques within pipelines as applied to securing assets against unauthorised access
Inventor: IAN JACKSON
IPC: G08B13/16
Filed: 2005-12-09
Granted: 2011-09-22
Abstract: Abstract That monitoring for an interruption or disturbance of regularly generated 0.1Hz. to 5 Hz air impulses traveling in a 3mm to 25mm diameter pipeline, placed around or near equipment or property boundaries, can be used as a method to secure said property or equipment against unauthorized access.
Patent AU-2005279293-B2 (AU)
Title: Gas flow control in a ventilator
Inventor: CEWERS GORAN
IPC: A61M16/12
Filed: 2005-09-01
Granted: 2012-02-16
Abstract: A ventilator or fluid delivery system that provides a flow of gas to an airway of a user. The ventilator includes a source of gas (30, 32), a conduit (63, 65, 42) that carries the flow of gas to the airway of a patient, a first valve (38, 40) that controls a pressure, flow, or volume, of the flow of gas, a pressure sensor (46) operatively coupled to the conduit between the valve and the patient and adapted to monitor a pressure of the gas in the conduit, and a controller (50) adapted to control the valve based on an output of the pressure sensor. The ventilator further includes a restrictor (62) provided in the conduit between the pressure sensor and the patient. The restrictor, in essence, divides the fluid delivery system such that a first volume is defined in the conduit between the valve and the restrictor and a second volume is defined in the conduit between the patient and the restrictor, wherein the first volume is less than the second volume. The control system controls the pressure, flow, or volume relative to the first volume so that an accurate, fast, and stable control of the pressure, flow, or volume is achieved.
Patent AU-2005291359-B2 (AU)
Title: Bioactive compositions, natural methods of producing them and computational methods for designing natural production processes
Inventor: PETER BLADEREN VAN
IPC: C12P21/06
Filed: 2005-10-07
Granted: 2011-10-13
Abstract: The present invention is directed to procedures for the controlled natural bioprocessing of naturally occurring biological molecules by processing activities present in select organisms, extracts of such organisms or other natural processing agents. The invention also covers the methods for developing these procedures and compositions prepared by the procedures.
Patent AU-2006203785-B2 (AU)
Title: A lock for a sliding door or window
Inventor: ALCHIN MICHAEL BRIAN
IPC: E05B65/08
Filed: 2006-08-30
Granted: 2012-05-03
Abstract: A LOCK FOR A SLIDING DOOR OR WINDOW Abstract A lock (10) for a sliding door or window. The lock (10) is intended to be operated by a key (104) operating a cylinder (49). The lock has a pin (55) that is moved to engage an eyelet (58) of a keeper (57). Fi v.9
Patent AU-2006207330-B2 (AU)
Title: Sunscreen compositions comprising carotenoids
Inventor: LYSAA PER AGE
IPC: A61Q5/06
Filed: 2006-01-23
Granted: 2013-05-23
Abstract: The invention concerns methods of treating or preventing the effects of irradiation in a human or non-human animal using carotenoid compounds, preferably diadinoxanthin, diatoxanthin and/or fucoxanthin as well as photoprotective compositions and their use to prepare photoprotective or photoprotected products.
Patent AU-2006251445-B2 (AU)
Title: Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen
Inventor: WOLF PHILIPP
IPC: A61K47/48
Filed: 2006-03-02
Granted: 2010-11-18
Abstract: Isolated monoclonal antibodies or an antigen binding portion thereof which bind to prostate specific membrane antigen in its native form occurring on the surface of tumor cells characterized in that it is linked to a label or a cytotoxic agent or constructed as a part of a bispecific antibody or a recombinant diabody.
Patent AU-2006289290-B2 (AU)
Title: Tumor-associated peptides binding promiscuously to human leukocyte antigen (HLA) class II molecules
Inventor: DENGJEL JORN
IPC: C07K14/47
Filed: 2006-09-05
Granted: 2010-11-25
Abstract: The present invention relates to immunotherapeutic methods, and molecules and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumour-associated T-helper cell peptide epitopes, alone or in combination with other tumour-associated peptides, that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumour immune responses. In particular, the present invention relates to 49 novel peptide sequences derived from HLA class II molecules of human tumour cell lines which can be used in vaccine compositions for eliciting anti-tumour immune responses.