baber/WOPTO huggingface dataset:
Patent CA-2742597-A1 (CA)
Inventor: PUTTA MALLIKARJUNA
IPC: A61K31/7088
Filed: 2009-11-04
Abstract: Antisense oligonucleotide compounds, compositions and methods are provided for down regulating the expression of TLR4. The compositions comprise antisense oligonucleotides targeted to nucleic acids encoding TLR4. The compositions may also comprise antisense oligonucleotides targeted to nucleic acids encoding TLR4 in combination with other therapeutic and/or prophylactic compounds and/or compositions. Methods of using these compounds and compositions for down-regulating TLR4 expression and for prevention or treatment of diseases wherein modulation of TLR4 expression would be beneficial are provided.
Patent CA-2742916-A1 (CA)
Inventor: TAUBER WOLFGANG
IPC: G01R29/08
Filed: 2010-02-04
Abstract: A method for detecting electromagnetic threats to an aircraft, wherein electromagnetic fields are measured, and in the case of an arising threat to the aircraft being detected, countermeasures are taken, characterised by the following steps:  -measuring the frequency and the amplitude of at least one electromagnetic field in the frequency range from 9 KHz to 40 GHz;  --analysing the measured results and determining the field intensity in relation to each measured frequency; - comparing the field intensity in relation to each measured frequency with stored limiting values or qualification values, wherein the aircraft is qualified for field intensities that are lower than the limiting values; and - providing the result in the form of a warning signal in the case of approaching or exceeding a limiting value.
Patent CA-2745456-A1 (CA)
Inventor: KANIKANTI VENKATA-RANGARAO
IPC: A23L27/30
Filed: 2009-11-24
Abstract: The invention relates to extrudates containing at least one pharmaceutically active substance in the form of needles, wherein the ratio of the particle size of the needle-shaped pharmaceutically active substance to the strand diameter is at least 1:15, and the use of these extrudates for the production of medicaments.
Patent CA-2745933-A1 (CA)
Title: Method for thiosulfate leaching of precious metal-containing materials
Inventor: JI JINXING
IPC: C22B1/00
Filed: 2001-05-18
Abstract: Processes are provided for recovering precious metals from refractory materials using thiosulfate lixiviants. The processes can employ lixiviants that include at most only small amounts of copper and/or ammonia and operate at a relatively low pH, reduction of polythionates, inert atmospheres to control polythionate production, and electrolytic solutions which provide relatively high rates of precious metal recovery.
Patent CA-2746561-A1 (CA)
Title: Dihydropyridone amides as p2x7 modulators
Inventor: LOPEZ-TAPIA FRANCISCO JAVIER
IPC: A61K31/4412
Filed: 2009-12-17
Abstract: Compounds of the formula (I) or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.
Patent CA-2747818-A1 (CA)
Inventor: BLACKFORD WOODY
IPC: A44B19/26
Filed: 2009-12-22
Abstract: Embodiments provide a weather resistant slide fastener with a modified slider body including a top control rib and tightly controlled inner dimensions. In embodiments, a water-resistant coating and/or an adhesive may be applied to the zipper tape, resulting in a highly water-resistant zipper and finished garment. Embodiments further provide a slider body that may accommodate longitudinal edge portions of the outer layer of fabric, allowing the edges of the fabric to be brought into close proximity/contact, substantially covering the zipper teeth and minimizing ingress of water and/or wind through the zipper tape. Additional embodiments provide methods of manufacturing and installing weather resistant slide fasteners.
Patent CA-2748397-A1 (CA)
Inventor: GIULIO MATASSA VICTOR
IPC: A61P25/00
Filed: 2009-12-15
Abstract: New derivatives of general formula (I), or pharmaceutically acceptable salts or N- oxides thereof wherein,either (i) A is selected from the group consisting of -N-, -O- and -S-; B and C are independently selected from the group consisting of -N- and -O-, with the proviso that two of A, B and C are nitrogen atoms, or (ii) two of A, B and C are -N- and one of A, B and C is -NH-; Gl is se-lected from the group consisting of -CH2-, -NH- and -O-;  G2 is selected from the group consisting of -NR4- and -O-;  R1 represents: > a 8 to 10 membered bicyclic N-containing heteroaryl group optionally substituted with a C1-4 car-boxyalkyl group or a C1-4 aminoalkyl group, > a pyridyl group optionally substituted with one or more substituents selected from hydroxy groups, C1-4 alkyl groups, C1-4 car-boxyalkyl groups, C1-4 haloalkyl groups, C1-4 alkoxy groups, amino groups, C1-4 aminoalkyl groups and C1-4 aminoalkoxy groups, > a pyridone group substituted with one or more C1-4 alkyl groups; C1-4 haloalkyl groups or C1-4 aminoalkyl groups, or > a group of formula:
Patent CA-2748919-A1 (CA)
Inventor: LAFFERTY TERRENCE P
IPC: A23L5/10
Filed: 2010-01-11
Abstract: A microwave heating construct includes a platform having a plurality of peripheral edges, a plu-rality of elevating panels for main-taining the platform in a raised posi-tion, and a layer of microwave ener-gy interactive material overlying at least a portion of the platform. The platform includes a movable portion defined at least partially by a line of disruption extending substantially between a pair of adjacent edges of the platform. The movable portion of the platform is adapted to pivot along the line of disruption.
Patent CA-2750622-A1 (CA)
Inventor: MORGAN PHILLIP D
IPC: A44B18/00
Filed: 2009-12-21
Abstract: A web buckle 30 with a pivot pawl 40 to receive non-inter-locking tongues insertable into the buckle. Push button 41 is biased upwardly by spring 39 within housing 44. Button 41 may be moved downward forcing pawl 40 to disengage the tongues. Pawl 40 is rockable to disengage the tongues one at a time.
Patent CA-2751769-A1 (CA)
Inventor: OKONIEWSKI GREGORY
IPC: A61B17/34
Filed: 2011-09-02
Abstract: A surgical apparatus, for positioning within a tissue tract to access an underlying body cavity, is provided. The surgical apparatus includes a first and second member. The first member has a proximal ramp section, an accordion section, and a retaining portion. The first member defines a first longitudinal axis, a first proximal end, and a first distal end. The second member has a tubular proximal section, a portal portion, and a distal flange.  The second member defines a second longitudinal axis, a second proximal end, and a second distal end. The second member includes a retaining structure to couple the first member to the second member. The first member is located at least partially in the tubular section of the second member.
Patent CA-2753029-A1 (CA)
Inventor: SHIMADA OSAMU
IPC: A61H39/06
Filed: 2010-02-12
Abstract: La présente invention concerne un dispositif de moxibustion électrique ayant une grande fonctionnalité et très sûr, et capable d'entraîner de manière efficace et fiable la pénétration d'un extrait de feuille de Loquat dans et sous la peau d'une partie affectée. Un dispositif de moxibustion électrique (1) est doté : d'un boîtier tubulaire (2) ayant une ouverture d'extrémité avant ; d'une unité de chauffage (4) prévue à l'intérieur du boîtier (2) à une position proche de l'ouverture d'extrémité avant ; et d'un capuchon (5) constitué par un caoutchouc thermorésistant et monté de manière amovible sur l'ouverture d'extrémité avant du boîtier (2). L'unité de chauffage (4) comprend une plaque métallique de transfert thermique (7) et un élément de génération de chaleur (6) qui est fixé à la surface arrière de la plaque métallique de transfert thermique (7) et qui génère de la chaleur par l'électricité alimentée d'une source d'énergie électrique externe (3) ou d'une batterie. Le capuchon (5) a une ouverture de décharge (14), fournie au centre de sa surface d'extrémité avant et destinée à décharger de la chaleur de l'élément générant la chaleur (6). Un élément (10) destiné à absorber et à retenir un liquide chimique, tel qu'un extrait de feuille de Loquat, est fourni à l'intérieur du boîtier (2) à une position entre la plaque métallique de transfert thermique (7) et l'ouverture de décharge (14) du capuchon (5).
Patent CA-2754228-A1 (CA)
Inventor: MARTIN PETER
IPC: A61M25/01
Filed: 2011-09-29
Abstract: A tunneler device is provided. The tunneler device includes a handle formed on a proximal end thereof configured for operable engagement by a user, a shaft extending distally from the handle, a collet supported on the distal end of the shaft, the collet including a plurality of distally extending fingers defining a longitudinal opening, the opening being configured to receive an end of a catheter tube and a connector configured for operable engagement with the collet, wherein the connector is configured to bias the fingers of the collet radially inward upon engagement of the connector with the collet.
Patent CA-2756047-A1 (CA)
Inventor: LENN JON
IPC: A61K31/23
Filed: 2010-03-19
Abstract: The present invention relates to a method of treating a fungal condition caused by T. rubrum, by administering a composition comprising a fatty acid monoester of glycerol. According to an embodiment, the fatty acid monoester of glycerol is 1-monocaprin. According to another embodiment, the fungal condition is onychomycosis
Patent CA-2758554-A1 (CA)
Inventor: STEWART JULIANNE
IPC: C08L91/06
Filed: 2011-11-17
Abstract: A wax remover for removing solidified wax within a wax container of a scent-warmer device includes a base having a size and shape configured to fit within a wax container of a scent-warmer device, and at least one tab attached to and extending from the base for removing the base from a wax container of a scented warmer device. Such wax removers are used to remove wax from a wax container of a scent-warmer device. A scent-warmer assembly includes a scent-warmer device that comprises a base housing a heat source, and a wax container configured to be heated by the heat source during operation of the scent-warmer device. The assembly further includes a wax remover disposed within the wax container, and a wax disposed at least partially over the wax remover within the wax container.
Patent CA-2760991-A1 (CA)
Inventor: LYNDERUP HENRIK FOMSGAARD
IPC: B63B35/44
Filed: 2011-12-06
Abstract: An arrangement for transporting a rotor of a wind turbine at sea is provided. The arrangement includes a vessel having a deck. Moreover, the arrangement includes at least one rotor including a hub and at least one blade affixed to the hub. The hub is positioned on the deck in such a way that the at least one blade is at least partially located above the sea surface and that the center axis of the hub is tilted in relation to the deck so as to increase the distance between the at least one blade and the sea surface. Furthermore, a method for transporting a wind turbine rotor at sea on a vessel having a deck is also provided.
Patent CA-2761752-A1 (CA)
Title: Polycationic amphiphilic cyclooligosaccharides and the use thereof as molecular transporters
Inventor: ORTIZ MELLET CARMEN
IPC: C12N15/88
Filed: 2010-04-14
Abstract: The present invention relates to a group of polycationic amphiphilic cyclooligosaccharides which, due to their molecular structure, may be used as molecular transporters to the interior of cells. Furthermore, the present invention also relates to the use of said compounds in the preparation of a medicament, to the use of this medicament for gene therapy and to a pharmaceutical composition that comprises one of said compounds.
Patent CA-2765399-A1 (CA)
Title: Sheet-fed duplex and sheet-fed duplex multi-color printers
Inventor: IZAWA HIDEO
IPC: G03G15/01
Filed: 2012-01-25
Abstract: To allow shortening the horizontal length for sheet-fed duplex printing while preventing a printing face of the sheet of paper printed on upstream in its conveyance direction from becoming soiled by toner transferred from a printing face of sheet of paper printed on downstream in its conveyance direction, a sheet-fed duplex printer comprises a pair of impression cylinders 6a, 6b each provided on a peripheral surface thereof with a paper gripper for gripping a sheet of paper, one of the impression cylinders in rotational contact with the other impression cylinder disposed downstream in a direction of rotation of and obliquely below the one impression cylinder. The two impression cylinders are synchronously rotated so that the regions of rotational contact thereof both move downwards. The sheet of paper reversing its printing face when the sheet of paper conveyed following a peripheral surface of the one impression cylinder is conveyed to follow that of the other impression cylinder. A first electrophotographic printing unit 7a is disposed opposite to a peripheral surface area of the one impression cylinder which area is upstream in the direction of rotation of the one impression cylinder from the region of rotational contact between the one and the other impression cylinder for printing on one face of the sheet of paper being conveyed following the peripheral surface of the one impression cylinder. A second electrophotographic printing unit 7b is disposed opposite to a peripheral surface area of the other impression cylinder which area is downstream in the direction of rotation of the other impression cylinder from the region of rotational contact between the one and the other impression cylinder for printing on the other face of the sheet of paper being conveyed following the peripheral surface of the other impression cylinder. And, a cleaning unit 23 for impression cylinder is disposed opposite to, and adapted to clean, a peripheral surface area of the other impression cylinder, the peripheral surface area of the other impression cylinder being downstream in the direction of its rotation from a position thereon at which the sheet of paper conveyed following the surface of the other impression cylinder is transferred therefrom downstream in the direction of conveyance of the sheet of paper.
Patent CA-2765946-A1 (CA)
Title: Multiple mode, portable patient monitoring system
Inventor: WALTERS PATRICIA RUTH
IPC: A61B5/08
Filed: 2010-04-27
Abstract: The specification discloses a number of embodiments directed to patient monitoring systems. The system determines a physiological parameter of a patient and includes an input device for receiving a plurality of physical inputs from a user, such as finger taps, and communicating to a memory interval data indicative of the frequency at which the plurality of physical inputs are received from the user within a time period and a processor in data communication with said memory wherein said processor determines at least one physiological parameter of a patient based upon said interval data.
Patent CA-2766210-A1 (CA)
Inventor: WEIDHAAS JOANNE B
IPC: C12Q1/68
Filed: 2010-06-25
Abstract: The invention provides methods for identifying mutations, such as single nucleotide polymorphisms (SNPs), within breast and ovarian cancer associated genes that modify the binding efficacy of micro RNAs (miRNAs). In a preferred embodiment, methods of the invention identify a SNP that decreases expression of the BRCA1 gene by increasing or decreasing the binding efficacy of at least one miRNA. Alteration of miRNA binding to BRCA1 by the introduction of SNPs within miRNA binding sites modulates or decreases BRCA1 expression, ultimately leading to the unregulated cell proliferation of a breast or ovarian cancer cells.
Patent CA-2767337-A1 (CA)
Title: Retractable bidet
Inventor: ALLARD JULES
IPC: A61H35/00
Filed: 2009-07-17
Abstract: A bidet usable with a water source and mountable to a toilet. The toilet includes a toilet bowl, the toilet bowl defining a bowl inner surface and a waterline defined on the bowl inner surface at an operational level of water in the toilet bowl, the toilet bowl also defining a bowl aperture extending therethrough below the waterline. The bidet includes a piston defining a piston passageway extending therethrough, the piston passageway being couplable to the water source for receiving water therefrom, the piston defining a nozzle for releasing water from the piston passageway. The bidet is operatively mountable to the toilet with the piston extending through the bowl aperture and protruding in the toilet bowl. With the bidet operatively mounted to the toilet bowl, the piston is movable through the bowl aperture between a retracted position and an extended position, the nozzle being substantially adjacent to the bowl inner surface and below the waterline when the piston is in the retracted position and the nozzle being spaced apart from the bowl inner surface and above the waterline when the piston is in the extended position.
Patent CA-2768348-A1 (CA)
Inventor: OLSEN WILLIAM W
IPC: G06Q40/00
Filed: 2010-07-15
Abstract: An apparatus (42) and methods (148, 192, 204) providing individuals and small businesses a simple and inexpensive way to collect information regarding their specific situation, identify and maximize available tax benefits, record various financial and non-financial information necessary to support the tax benefits, and systematically work toward growing the business.
Patent CA-2770229-A1 (CA)
Title: Fishing rod assembly
Inventor: TRILLER WOLFGANG
IPC: A01K87/06
Filed: 2010-07-23
Abstract: A fishing rod assembly comprises a fishing rod (2, 12) and a fishing reel (3, 13) having a foot (4, 14) which serves to fasten the fishing reel to the fishing rod and is characterized in that both the foot (4, 14) of the fishing reel (3, 13) and the fishing rod (2, 12) have respective recesses (18, 23) for jointly receiving at least one detachable fastening means (6, 25) for immobilizing the fishing reel on the fishing rod.
Patent CA-2772663-A1 (CA)
Inventor: KOVATCHEV BORIS P
IPC: G16Z99/00
Filed: 2010-09-02
Abstract: A method, system and related computer program product for tracking the probability of hypoglycemia from routine self-monitoring of blood glucose (SMBG) data in patients with diabetes. A specific bivariate probability distribution of low BG events based jointly on the Low BG Index (LBGI) and the Average Daily Risk Range (ADRR) is used to predict hypoglycemia probability of occurrence from inputted SMBG data. The SMBG data is retrieved from a series of SMBG data of a patient available from the patient's glucose meter and allows tracking of the probability for future hypoglycemia over a predetermined duration, e.g. a 24 or 48 hour period. The tracking includes presentation of visual and/or numerical output, as well as construction of hypoglycemia risk trajectories that would enable warning messages for crossing of predefined thresholds, such as 50% likelihood for upcoming hypoglycemia below 50mg/dl.
Patent CA-2774153-A1 (CA)
Title: Forme galenique capable d'adsorber de maniere specifique les molecules indesirables presentes dans le tube disgestif
Inventor: FATTAL ELIAS
IPC: A61K31/722
Filed: 2010-09-22
Abstract: La présente invention se rapporte à une forme galénique comprenant des particules capables d'adsorber, de manière spécifique, les molécules indésirables présentes dans le tube digestif, son procédé de préparation et son utilisation notamment pour la fabrication d'un médicament destiné à la prévention ou au traitement des effets indésirables liés à un déséquilibre de la flore intestinale et/ou colique pouvant résulter par exemple d'une antibiothérapie.
Patent CA-2774223-A1 (CA)
Title: Methods and compositions for diagnosis and prognosis of renal injury and renal failure
Inventor: ANDERBERG JOSEPH
IPC: G01N33/68
Filed: 2010-09-21
Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a plurality of assays, one or more of which is configured to detect a kidney injury marker selected from the group consisting of metalloproteinase inhibitor 2, soluble oxidized low- density lipoprotein receptor 1, interleukin-2, von Willebrand factor, granulocyte- macrophage colony- stimulating factor, tumor necrosis factor receptor superfamily member HB, neutrophil elastase, interleukin- 1 beta, heart- type fatty acid-binding protein, beta-2-glycoprotein 1, soluble CD40 ligand, coagulation factor VII, C-C motif chemokine 2, IgM, CA 19-9, IL-IO, TNF-a, and myoglobin as diagnostic and prognostic biomarkers in renal injuries.
Patent CA-2776520-A1 (CA)
Title: A multimode multicarrier modem system and method of communication over the same
Inventor: HELLER PETER N
IPC: H04L45/60
Filed: 2001-05-23
Abstract: An alternative approach to coping with the ever increasing demand for faster communications hardware is to design modems that are capable of operating its speeds at a higher data rate than a speed required for a single port of the standard communication rate for that modem. Basically, by utilizing a resource manager, that directs the data in and out of the various portions of the modem in an orderly manner, keeping track of which of the ports is being operated at any given point in time, a standard single port modem can be reconfigured, for example, at an over clocked rate, to manipulate the data input and output of a modem.
Patent CA-2776646-A1 (CA)
Title: Connecteur pour systeme de chirurgie laparoscopique
Inventor: JOSHI SHARAD H
IPC: A61B17/94
Filed: 2012-05-10
Abstract: Un raccord permettant de raccorder la pointe d'un instrument à l'extrémité d'un tube laparoscopique, le raccord comprenant une base formant le corps de ce dernier, la base comportant une lumière configurée afin d'y accueillir un dispositif d'actionnement de pointe d'instrument, et un joint d'étanchéité lié en permanence à la surface interne de l'extrémité proximale de la base et configuré pour se déformer au moment du raccordement du raccord avec l'extrémité du tube.
Patent CA-2779471-A1 (CA)
Title: Golf shot tracking system
Inventor: MEADOWS JAMES W
IPC: A63B69/36
Filed: 2010-11-08
Abstract: A golf tracking system including a tag coupled to a golf club. The tag includes a plurality of sensors, each which output a signal based on a detected movement of the golf club, a microcontroller that compares each of the plurality of sensor outputs to stored reference sensor output values, and a transceiver that transmits data corresponding to the sensor outputs to a device remote from the tag based on the comparison performed by the microcontroller. The location-aware device then processes the information received from the tag to determine whether a shot should be registered.
Patent CA-2781901-A1 (CA)
Inventor: MALCUIT ISABELLE
IPC: A01H5/00
Filed: 2009-11-25
Abstract: La présente invention concerne un procédé pour la production d'espèce d'ARN et de protéine hétérologue dans des mitochondries de cellule de plante comprenant l'introduction dans des cellules de plante de composants d'acide nucléique qui codent pour des protéines/ARN hétérologues sous le contrôle de promoteurs fonctionnels dans des mitochondries, des vecteurs, des cellules hôtes, des plantes et des utilisations de ceux-ci.
Patent CA-2783978-A1 (CA)
Inventor: SHOWMAN RALPH E
IPC: C04B14/00
Filed: 2010-10-27
Abstract: Disclosed is a foundry mix containing a carbonate salt and its use to make foundry shapes by the warm-box, hot-box, no-bake, and cold-box process, the use of these foundry shapes to make metal castings, and the metal castings prepared by the process.