baber/WOPTO huggingface dataset:
Patent CA-3073738-A1 (CA)
Title: Hollow fiber membrane filtration systems and methods for manufacturing biologically-produced products
Inventor: LOVE J CHRISTOPHER
IPC: B01D63/02
Filed: 2018-08-31
Abstract: Aspects of the present disclosure relate to filtration systems and methods for production of biologically-produced products, which may include pharmaceutical and/or protein products. Certain biomanufacturing systems described herein comprise a bioreactor (e.g., a perfusion bioreactor, a chemostat) and a filter probe comprising a filter bundle comprising a plurality of hollow fibers (e.g., longitudinally aligned hollow fibers). According to some embodiments, a center-to-center distance between any two hollow fibers within the fiber bundle at one or more points along a length of the fiber bundle is relatively large (e.g., greater than or equal to an average outer diameter of the hollow fibers of the fiber bundle, greater than or equal to 1.1 times a minimum diameter of the two hollow fibers). In some embodiments, the hollow fibers within the fiber bundle are arranged in an array (e.g., a hexagonal, linear, annular, or square array).
Patent CA-3075650-A1 (CA)
Title: Agent anticancereux
Inventor: DILLON CAROLYN THERESE
IPC: A61K47/64
Filed: 2018-10-17
Abstract: La présente invention concerne un agent anticancéreux comprenant un peptide de tropisme de tumeur ayant, ou ayant été modifié pour présenter, deux résidus cystéines, avec un atome d'arsenic entre eux, de sorte que le peptide de tropisme de tumeur effectue une cyclisation pour donner un agent anticancéreux contenant de l'arsenic. Ceci permet la sélection d'un peptide de tropisme de tumeur approprié pour le traitement d'un cancer donné moyennant quoi l'agent ultérieur fournit une administration plus ciblée de l'arsenic au microenvironnement tumoral.
Patent CA-3077342-A1 (CA)
Title: Gastroretentive sustained release formulations of bergenia ciliata
Inventor: BHARATE SONALI SANDIP
IPC: A61K9/48
Filed: 2018-09-11
Abstract: The present invention is related to a novel gastroretentive swellable oral dosage form for sustained or delayed release of bergenin, a active constituent of Bergenia ciliata extract/fraction and a process for preparing the same wherein the extract is wet-granulated using excipients i.e. biodegradable polymers and/ or non-biodegradable polymers alone or in combination, and the said granules are either filled into a capsule or compressed into a tablet. The said formulation comprising a granulated extract of bergenin-rich Bergenia ciliata with polymers has resulted in a sustained release of extract in the stomach over a period of 16-24hrs. The said formulations are useful for the treatment of inflammatory diseases.
Patent CA-3079644-A1 (CA)
Title: Filtre pour article a fumer ou pour produit de generation d'aerosol
Inventor: MIAH REZAUL
IPC: A24D3/17
Filed: 2018-10-23
Abstract: L'invention concerne un filtre pour un article à fumer ou pour un produit de génération d'aérosol, comprenant une première section de filtre et une seconde section de filtre, la seconde section de filtre étant située en aval de la première section de filtre ; la première section de filtre comprend un matériau de filtre et au moins deux capsules comprenant un additif, les capsules étant disposées dans une région axiale proximale par rapport à un axe longitudinal du filtre et espacées séquentiellement le long de l'axe ; la seconde section de filtre comprend au moins un canal situé dans une région axiale de la seconde section de filtre proximale par rapport à un axe longitudinal du filtre, afin de permettre, lors de l'utilisation, le prélèvement d'un aérosol à travers la région axiale de la première section de filtre dans laquelle les capsules sont disposées.
Patent CA-3080666-A1 (CA)
Title: Horizontal portion of a frame in a stud wall and installation tool therefor
Inventor: BELANGER GHISLAIN
IPC: E06B1/04
Filed: 2020-05-13
Abstract: A horizontal portion of a frame, as a door header, of a predetermined length for installation between two adjacent studs of a stud wall spaced from one another.  An installation tool, releasably mounted on a respective stud via a magnetic attachment, supports a respective end of the horizontal portion adjacent the metallic stud during attachment of the horizontal portion to the stud. A kit formed of at least one horizontal portion and at least one installation tool is also provided.
Patent CA-3081622-A1 (CA)
Title: Intelligent self-powered camera
Inventor: BEACH ALLISON
IPC: G06V10/764
Filed: 2018-10-30
Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for monitoring wildlife using a self-powered camera. The methods, systems, and apparatus include actions of detecting an object near a camera, in response to detecting the object near the camera, classifying the object as a particular type of animal based on an appearance of the object in an image captured by the camera, determining whether to provide a notification regarding the image based on the particular type of animal that the object is classified as, and in response to determining to provide a notification regarding the image based on the particular type of animal that the object is classified as, providing the notification regarding the image.
Patent CA-3082117-A1 (CA)
Title: Methodes et compositions pour le traitement du cancer par la modification de multiples bras du systeme immunitaire
Inventor: NANDABALAN KRISHNAN
IPC: A61K31/69
Filed: 2018-11-13
Abstract: La présente invention concerne des polythérapies et des compositions pour des thérapies anti-cancéreuses. Les associations modifient de multiples bras du système immunitaire, comprenant un modificateur d'immunité innée, un inhibiteur de point de contrôle immunitaire et un stimulateur de lymphocytes T, pour traiter le cancer.
Patent CA-3082394-A1 (CA)
Title: Wheat based binding agent
Inventor: CARSON BROOK
IPC: A21D13/062
Filed: 2018-11-13
Abstract: Provided herein are compositions that are useful as binding agents for clusters, bars, and other food applications where various components need to be adhered to each other. The binding agents comprise a wheat protein isolate in combination with flour and water.
Patent CA-3082518-A1 (CA)
Title: Sutures et appareils medicaux connexes
Inventor: GEMETTA TIFFANY
IPC: A61B17/06
Filed: 2018-12-20
Abstract: Divers aspects de la présente invention concernent des appareils, des systèmes et des procédés qui comprennent un cordon qui est flexible et allongé et définissant une longueur. Le cordon peut comprendre un noyau ayant une surface poreuse et un élément de réduction de porosité sur au moins une partie du noyau.
Patent CA-3083615-A1 (CA)
Inventor: MACINNIS BRENT
IPC: B82Y20/00
Filed: 2017-12-21
Abstract: Conventional eyewear devices such as spectacles typically include one or more refractive lenses. Such lenses may be thick or bulky. According to an aspect of the disclosure, a metalens-based eyewear devices is provided. The eyewear device includes one or more lenses. Each lens comprises a substantially transparent lens body. Each lens further comprises at least one metalens integrated with the body. Each metalens comprises a respective substantially transparent substrate, and a respective plurality of subwavelength structures arranged on the substrate in a pattern to interact with visible light. The lens body may be planar. The lenses of such eyewear (including at least one metalens) may be thinner and/or lighter than conventional refractive lenses.
Patent CA-3083973-A1 (CA)
Title: Method for forming three-dimensional texture on plastic floor
Inventor: DAI HUIBIN
IPC: E01C23/08
Filed: 2019-11-20
Abstract: A method for forming a three-dimensional texture on a plastic floor, the method comprising the following steps: printing colour pigment on an outer surface of a substrate (40) according to a preset texture pattern using a digital printing unit (10) to form a pattern layer (42), wherein the outer surface of the substrate (40) is blank or plain; forming a transparent molten plastic raw material onto the pattern layer (42) by using a first forming unit (20) so as to form a protective layer (43); and forming an uneven three-dimensional texture (44) on the protective layer (43) by using a second forming unit (30) so as to form a plastic floor having the three-dimensional texture (44). The pattern of the plastic floor can be designed by oneself, and the three-dimensional aesthetics are strong.
Patent CA-3085066-A1 (CA)
Title: Formulations providing high nicotine concentrations
Inventor: NIELSEN BRUNO PROVSTGAARD
IPC: A61K47/02
Filed: 2018-12-07
Abstract: The invention relates to an oral nicotine formulation for use in the alleviation of nicotine craving, the formulation comprising a content of nicotine and a content of a pH regulating agent, wherein the formulation is designed for the content of nicotine to dissolve in the oral saliva within a period of less than 90 seconds upon oral administration, and wherein at least 40% by weight of the nicotine is absorbed through the oral mucosa.
Patent CA-3085219-A1 (CA)
Inventor: HUBINETTE FREDRIK
IPC: A61K47/26
Filed: 2018-12-20
Abstract: A method of preparing a mucoadhesive film containing vardenafil or a pharmaceutically acceptable salt of vardenafil, by admixing, in an aqueous liquid carrier, vardenafil or a pharmaceutically acceptable salt of vardenafil, a C3-C12 polyol, and a pH regulating agent, to obtain a liquid composition having a pH of at least 4.2; admixing the liquid composition with analginate salt of monovalent cation or a mixture of such salts, distributing the obtained composition onto a solid surface; and permitting the composition to dry. A mucoadhesive film containing vardenafil or a pharmaceutically acceptable salt of vardenafil, its use for treating sexual dysfunction.
Patent CA-3085220-A1 (CA)
Inventor: RAINS GERALD E
IPC: A01B69/00
Filed: 2020-06-29
Abstract: An agricultural planter is configured to be moved over a supporting surface by a vehicle.  The agricultural planter includes a frame and a planter assembly coupled to the frame. A first propulsion assembly is coupled to the frame at a first position with the first propulsion assembly having a first traction member configured to engage the supporting surface. A  second propulsion assembly is coupled to the frame at a second position with the second propulsion assembly having a second traction member configured to engage the supporting surface. A drive assembly is operably coupled to at least one of the first or second propulsion assemblies and configured to drive at least one of the first or second traction members during operation of the planter assembly.  The first traction member is configured to be driven independently of the second traction member.
Patent CA-3086389-A1 (CA)
Inventor: CANETE MARTINEZ ANTONIO
IPC: H04L12/24
Filed: 2018-01-10
Abstract: Il est décrit un procédé et un noeud de gestion permettant de gérer un échange d'informations associées à des descripteurs de flux de paquets entre un serveur d'application et un noeud d'exposition de réseau. Le noeud de gestion reçoit un message comprenant un descripteur de flux de paquets avec un identifiant de descripteur de flux de paquets, un identifiant d'application externe associé au descripteur de flux de paquets, un identifiant de serveur du serveur d'application, un identifiant de transaction et un identifiant d'exposition de réseau identifiant un réseau d'opérateur. Le noeud de gestion mémorise des informations reçues. Le noeud de gestion sélectionne, sur la base de l'identifiant d'exposition de réseau, un noeud d'exposition de réseau. Lorsqu'un identifiant de sélection de descripteur de flux de paquets est compris dans le message, le noeud de gestion sélectionne, sur la base de l'identifiant de sélection de descripteur de flux de paquets, un autre descripteur de flux de paquets parmi l'ensemble de descripteurs de flux de paquets mémorisés. Le noeud de gestion détermine également une action concernant l'autre descripteur de flux de paquets. Autrement, le noeud de gestion transmet, vers le noeud d'exposition de réseau, le descripteur de flux de paquets et une indication de l'action.
Patent CA-3088832-A1 (CA)
Title: Regulatory t cell expressing a chimeric antigen receptor
Inventor: NOWAK ANNA
IPC: A61K35/17
Filed: 2019-01-17
Abstract: The present invention provides a regulatory T (Treg) cell expressing an antigen chimeric receptor (CAR) comprising a) at least one antigen binding domain, b) a transmembrane domain, and c) a cytoplasmic signaling domain comprising at least one primary cytoplasmic signaling domain and at least the co-stimulatory signaling domain of CD137, wherein said antigen binding domain specifically binds an antigen that is expressed on the surface of a target cell or a tag of a tagged polypeptide that binds to an antigen expressed on the surface of a target cell or a soluble antigen. Compositions comprising said Treg cells, and methods of enrichment and analysis of activated Tregs that express said CAR are also disclosed.
Patent CA-3089098-A1 (CA)
Title: Structure stratifiee, construction et leurs procedes d'utilisation
Inventor: GILPATRICK WILLIAM
IPC: B32B37/12
Filed: 2018-06-13
Abstract: La présente invention concerne une structure stratifiée comprenant une couche de base, un adhésif thermiquement stable disposé sur au moins une partie de la couche de base, et un suscepteur recouvrant la couche de base et l'adhésif thermiquement stable. L'adhésif thermiquement stable maintient sensiblement le profil thermique du suscepteur à une température supérieure ou égale à environ 250 °F (121 °C).
Patent CA-3090604-A1 (CA)
Title: Modular electrical distribution system for an illuminable decoration, and illuminable decoration with modular electrical distribution system
Inventor: TSAI CHANG FU
IPC: H01R24/38
Filed: 2020-08-20
Abstract: An illuminable decoration comprises at least two trunk sections, each trunk section includes a hollow tube and a cable assembly coupled to each trunk section. Each cable assembly comprises a first modular electrical connector end that has an inner socket and an outer plug that circumscribes the inner socket. Further, each cable assembly comprises a second modular electrical connector end that has an inner plug and an outer socket that circumscribes the inner plug. A first electrical wire electrically couples between the inner socket of the first modular electrical connector and the inner plug of the second modular electrical connector. Also, a second electrical wire electrically couples between the outer plug of the first modular electrical connector and the outer socket of the second modular electrical connector. When two trunk sections are assembled together end-to-end, the trunk sections are mechanically and electrically coupled to form a modular electrical distribution system.
Patent CA-3092107-A1 (CA)
Inventor: ASOKAN ARAVIND
IPC: C12N15/861
Filed: 2019-02-28
Abstract: The present disclosure provides AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the modified AAV capsid protein. The disclosure also provides methods of administering the virus vectors and virus capsids of the disclosure to a cell or to a subject in vivo. This disclosure also relates to recombinant adeno associated virus (rAAV) capsid proteins comprising one or more amino acid substitutions in the 5-fold region of the rAAV capsid that result in decreased reactivity to neutralizing antibodies, and their use as gene delivery vehicles.
Patent CA-3092140-A1 (CA)
Title: Procede de reduction des dommages causes aux cultures
Inventor: BICKERS UDO
IPC: A01N43/40
Filed: 2019-02-26
Abstract: La présente invention concerne un procédé de réduction des dommages causés aux cultures par traitement de la semence des cultures avec le phytoprotecteur avant le semis. Ceci peut être réalisé en plus de l'utilisation de combinaisons/compositions de protection des cultures, en particulier des combinaisons herbicide/phytoprotecteur et des compositions les comprenant, qui sont hautement appropriées pour la protection des cultures contre des dommages causés par des herbicides dans des traitements avant la levée et après la levée.
Patent CA-3093554-A1 (CA)
Inventor: REARDEN JIM
IPC: B01D63/02
Filed: 2019-03-13
Abstract: The present invention provides modular devices and systems for infusing gas into a liquid and methods of manufacture and use thereof. In accordance with an embodiment, a modular device for infusing gas into a liquid is provided. The modular device comprises a plurality of microporous hollow fibers, and a cap covering open ends of the microporous hollow fibers. The cap is configured to receive a gas into an opening and to deliver the gas into the open ends of the microporous hollow fibers. The cap is further configured to removably mount the modular device to a fixture. A system for infusing gas into a liquid may include one or more of the modular gas infusion devices configured to be removably mounted to a fixture such that the microporous hollow fibers are within a hollow cavity.
Patent CA-3094912-A1 (CA)
Title: Retrofit rear curbside door for vehicle
Inventor: HAMRICK LEONARD M
IPC: B60J5/04
Filed: 2020-09-30
Abstract: A rear curbside door assembly includes a door frame, a door, and a support member. The door frame includes first and second side frame members, an upper frame member and at least one stair. The second side frame member is spaced from the first side frame member and is configured for releasable attachment to a D-pillar of a body of a vehicle. The upper frame member extends between the first and second side frame members. The at least one stair extends between the first and second side frame members and is spaced from the upper frame member. The door is pivotally coupled with the door frame. The support member is configured for releasable attachment to a body of a vehicle. The support member is releasably attached to the first side frame member. A  vehicle including a rear curbside door assembly and methods thereof are also provided.
Patent CA-3102021-A1 (CA)
Title: Methods of forming ceramic matrix composites using sacrificial fibers and non-wetting coating
Inventor: DUNN DANIEL GENE
IPC: C04B41/91
Filed: 2020-12-09
Abstract: 328251-2 AB STRACT Methods for preparing ceramic matrix composites using melt infiltration are provided as well as the resulting ceramic matrix composites. The methods and products include the incorporation of a non-wetting coating to one or more sacrificial fibers. The one or more sacrificial fibers are removed, such as decomposed during pyrolysis, resulting in the formation of a plurality of functional features, in the form of regular and elongate channels along the ceramic matrix composite. During the removing of the one or more sacrificial fibers, the non-wetting coating remains on an interior surface of the plurality of functional features to block infiltration of an infiltrant to the plurality of functional features and deposition thereon. Alternatively, the sacrificial fibers may be removed subsequent to melt infiltration. Date Recue/Date Received 2020-12-09
Patent CA-3102474-A1 (CA)
Inventor: FOGAL STEFANO
IPC: C12P13/04
Filed: 2019-06-07
Abstract: The present invention relates to a process for the preparation of Droxidopa by means of an improved enzymatic reduction of a compound of formula (II): (II), wherein R1, R2 is independent hydrogen, acetyl, R3 is hydrogen, a C1-C4 linear or branched alkyl group and R4 is hydrogen or an amine protecting group.
Patent CA-3102730-A1 (CA)
Title: Acupuncture needle and method of forming acupuncture needle
Inventor: NAKANO RYOICHI
IPC: B21G1/00
Filed: 2020-12-16
Abstract: A method of forming an acupuncture needle includes forming an acupuncture needle 1 having a needle body 2 having a needle tip portion 2a at a leading end thereof, and a needle grip 3 attached to a base end portion of the needle body 2. A cross-sectional shape crossing a longitudinal direction of the needle grip 3 of the acupuncture needle 1 at a middle of the needle grip 3 of the acupuncture needle 1 in the longitudinal direction is an ellipse. A groove portion 4 is provided along an outer circumference of the needle grip 3. When using as an acupuncture needle 1 with a long needle grip, the needle grip 3 is maintained without being separated at the groove portion 4. When using as an acupuncture needle 1 with a short needle grip, the needle grip 3 is bent with a bending load direction in a minor axis direction of the cross-sectional shape being the ellipse to separate the needle grip 3 at the groove portion 4 and form the acupuncture needle 1 having the needle grip 3 shorter in length in the longitudinal direction than the needle grip 3 before being separated.
Patent CA-3104694-A1 (CA)
Title: Procede de traitement de reflux de fracturation et d'eau produite comprenant une matiere radioactive naturelle
Inventor: BANERJEE KASHI
IPC: C02F9/00
Filed: 2019-07-08
Abstract: L'invention concerne un procédé de traitement de reflux de fracturation renfermant du baryum, des matières radioactives naturelles (NORM) et une dureté pour minimiser la quantité de boues produites contenant des niveaux dangereux de NORM par l'utilisation d'un procédé de précipitation à deux étapes. Dans la première étape, une source de sulfate est mélangée avec le reflux de fracturation, le sulfate de baryum et le NORM sont précipités et le reflux de fracturation est soumis à un processus de séparation solide-liquide pour produire un premier effluent et une première boue. Dans la seconde étape, la dureté est précipitée à partir du premier effluent par ajout d'un réactif alcalin, ledit premier effluent étant également soumis à une séparation solide-liquide produisant un second effluent et une seconde boue. La première boue est recyclée et mélangée avec le reflux de fracturation et la source de sulfate dans une quantité suffisante pour maintenir la concentration de NORM dans la seconde boue au niveau ou au-dessous d'un niveau de seuil.
Patent CA-3104712-A1 (CA)
Inventor: LANGGUTH TORSTEN
IPC: H04L45/52
Filed: 2020-12-31
Abstract: The invention relate to a system for transmitting time-critical analog signals and/or digital signals between a first device (12) and a second device (14).  The system (10) comprises at least a first protocol converter (18) connected to the first device (12) and at least a second protocol converter (20) connected to the second device (14). A data transmission network (26) for transmission of data packets is provided between the protocol converters (18, 20). The data transmission network (26) is established by an internet protocol network. The system (10) comprises a port redirector (28, 29) associated with at least one of the protocol converters (18, 20). The port redirector (28, 29) is configured to convert a protocol for serial data transfer into the transmission control protocol, thereby generating the data packets, or to convert the transmission control protocol associated with the data packets into a protocol for serial data transfer. The system (10) is configured to process asynchronous data and synchronous data. Further, a method of transmitting time-critical analog signals and/or digital signals is provided.
Patent CA-3106008-A1 (CA)
Title: Vesicules contenant une bicouche lipidique binaire comprenant des agents cytotoxiques noyes et leurs procedes de fabrication et d'utilisation
Inventor: PURI ANU
IPC: A61K31/4745
Filed: 2019-07-11
Abstract: Conformément à des modes de réalisation, la présente invention concerne des vésicules comprenant des agents cytotoxiques noyés, ainsi que des procédés de fabrication et d'utilisation des vésicules. La présente invention concerne également des compositions pharmaceutiques comprenant les vésicules. Les vésicules comprennent une bicouche lipidique binaire entourant une cavité, la bicouche lipidique binaire vésiculaire comprenant (i) un lipide non de formation de bicouche (ou une combinaison de lipides non de formation de bicouche) et un lipide pégylé; et (i) un agent cytotoxique noyé à l'intérieur de la paroi vésiculaire.