baber/WOPTO huggingface dataset:
Patent CA-2561746-A1 (CA)
Inventor: YAO ZEMIN
IPC: A61K45/00
Filed: 2004-12-13
Abstract: The invention provides uses of autophagocytosis inducing compounds for reducing serum levels of triglycerides and VLDL and the preparation of medicaments. The invention also provides the use of autophagocytosis inducing compounds for treating hypertriglyceridemia, hyperlipidemia, hypercholesterolemia, hyperlipoproteinemia, atherosclerosis, arteriosclerosis, peripheral artery disease, coronary artery disease, congestive heart failure, myocardial ischemia, myocardial infarction, ischemic stroke, hemorrhagic stroke, or diabetes, insulin resistance, hemodialysis, glycogen storage disease type I, polycystic ovary syndrome, combination thereof. The invention further provides methods of identifying compounds which modulate autophagocytosis.
Patent CA-2564067-A1 (CA)
Inventor: VAN DIJK JOHANNES HENRICUS
IPC: C12G3/06
Filed: 2005-04-22
Abstract: The present invention relates to a stable alcoholic milk and/or soy protein-based drink with a pH in the range from 5.2-6.5, preferably 5.2-C.2, comprising at least one or more milk and/or soy proteins, alcohol and one or more stabilizers. Furthermore, the invention relayes to a method for preparing a staff e alcoholic milk and/or soy protein-based drink with a pH in the range from 5.2-6.5, comprising as constituents at least one or more milk and/or soy proteins, alcohol and one or more stabilizers, which method comprises the following steps: a) mixing at least a portion of the milk and/or soy proteins and at least a portion of the stabilizers in an aqueous medium to obtain a mixture; b) setting the pH of the mixture to 3.5-4.4; c) homogenizing the mixture obtained in step b) to obtain a homogenate; d) setting the pH of the homogenate to 5.2-6.5; and e) mixing in the alcohol and optionally a residual portion of the milk and/pr soy proteins and of the stabilizers during or after one or more of steps a)-d).
Patent CA-2565193-A1 (CA)
Title: Method for preparing a suspension containing phosphate
Inventor: YLINEN PAULA
IPC: C05G3/50
Filed: 2005-05-19
Abstract: The invention relates to a method for preparing a suspension containing phosphate stepwise directly from raw materials, from phosphoric acid of fertilizer quality, a base and organic additives. In accordance with the method, the phosphoric acid is preneutralised with the base, the organic additives are added, nucleation is controlled and phosphate salts are cooling crystallised in order to form a suspension. The phosphate suspension prepared with the method of the invention is applicable to seed coating.
Patent CA-2566445-A1 (CA)
Inventor: PENG GIIA-SHUEN
IPC: A61K38/08
Filed: 2005-05-12
Abstract: L'invention comprend des procédés de neuroprotection, induisant la libération de facteurs neurotrophiques, inhibant la sur-activation de cellules immunes innées, atténuant la mort et/ou l'endommagement de tissus induit par des toxines, réduisant l'inflammation, traitant une affection liée à une inflammation et inhibant la NADPH oxydase, lesquels comprennent de mettre en contact avec ou d'administrer une quantité efficace d'au moins un composé de l'invention qui comprend : de l'acide valproïque, du butyrate de sodium et des sels de ceux-ci ; des peptides d'opioïdes ; un peptide comprenant le tripeptide GGF ; et des morphinanes tels que le naxolone, le naltrexone, le 3-hydroxy-morphinane et le dextrométhorphane.
Patent CA-2568350-A1 (CA)
Title: Water treatment system and process
Inventor: WILKINS FREDERICK
IPC: C02F1/28
Filed: 2005-05-27
Abstract: A system and process for treating water are described. Water may be purified by passing feed water through a carbon filter (10), a particulate filter (20), and an electrochemical deionization device (30). The water may be suitable for cooking, washing, and beverage production.
Patent CA-2572341-A1 (CA)
Title: Dispenser with material-recognition apparatus and material-recognition method
Inventor: RODRIAN JAMES A
IPC: B65H43/00
Filed: 2004-06-30
Abstract: Dispenser apparatus (1, 3) for dispensing flexible sheet material (1001) including material- recognition apparatus permitting the dispenser to recognize sheet material from an authorized source and to be enabled for operation with such material. The material-recognition apparatus may include a sensor (138) mounted in the dispenser in position to scan a code (10 19), preferably located on the core (1005) on which the sheet material is wound.  The sensor generates a code signal corresponding to the code. A control circuit (49) receives and validates the code signal. Sheet material dispensing is allowed if the code is valid or is not allowed if the code is invalid.
Patent CA-2572442-A1 (CA)
Inventor: SANCHEZ MURIEL
IPC: C07D215/56
Filed: 2005-07-26
Abstract: L'invention concerne un composé hybride aminoquinoléine-antibiotique défini par la formule générale (I) : Q - (Y1)p - (U)p' - (Y2)p'' - A ; dans laquelle Q représente une aminoquinoléine, (Y1)p - (U)p' - (Y2)p'' - est un bras espaceur éventuel et A est un résidu antibiotique. L'invention permet d'améliorer de manière inattendue l'activité du résidu antibiotique.
Patent CA-2575645-A1 (CA)
Title: Soluble amide & ester pyrazinoylguanidine sodium channel blockers
Inventor: JOHNSON MICHAEL R
IPC: A61K31/4965
Filed: 2005-05-20
Abstract: The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.
Patent CA-2575702-A1 (CA)
Title: Oxindole oxazolidinones as antibacterial agents
Inventor: GORDEEV MIKHAIL FEDOROVICH
IPC: A61P31/04
Filed: 2005-07-19
Abstract: The present invention relates to novel oxazolidinones derivatives of oxindoles of formula I or a pharmaceutically acceptable salt thereof wherein: Y1 is CH  or CF; R1 is -C1-4alkyl, optionally substituted with a fluoro atom, or R1 is -C3-5cycloalkyl; and R2 is -C1-2alkyl. These compounds are useful as antibacterial agents.
Patent CA-2575930-A1 (CA)
Inventor: GRIER WAYNE C
IPC: H02G3/14
Filed: 2007-01-17
Abstract: A cover plate for an electrical box includes a plate having a front face and a back face.  At least one male member extends perpendicularly from the back face of the plate. Each male member is adapted for press fit frictional engagement with a screw receiving aperture.
Patent CA-2576471-A1 (CA)
Title: Self-calibrating shooter estimation
Inventor: BRINN MARSHALL SETH
IPC: F41J5/06
Filed: 2005-08-11
Abstract: Shockwave-only solutions that estimate shooter position and shot trajectory are extremely sensitive to the quality and precision of the shock time-of-arrival (TOA) measurements as well as the accuracy to which relative sensor positions in space are known. Over the life of a long-deployed system, the sensor positions can shift and the performance of some sensors may degrade for various reasons. Such changes can degrade the performance of deployed shooter estimation systems. Disclosed are systems and methods that can be used to calibrate sensor positions based on shock and muzzle measurements processed from a series of shots fired from a known location and in a known direction, as well as an approach for dynamically adapting shock-only shooter estimation algorithms to compensate for sensor degradation and/or loss.
Patent CA-2576928-A1 (CA)
Title: Sofc stack concept
Inventor: DEKKER NICOLAAS JACOBUS JOSEPH
IPC: H01M8/02
Filed: 2005-08-18
Abstract: Fuel cell consisting of simple components. This fuel cell is preferably constructed as anode-supported solid oxide fuel cell, but can also be used with electrolyte- and metal- supported solid oxide fuel cells. The anode and electrolyte are larger than the cathode and the portion of the anode/electrolyte protruding beyond the cathode is provided with a peripheral seal. The anode/electrolyte/cathode combination is provided with a flow/gas distribution grid on both the anode and the cathode side. The anode/cathode combination including the flow/gas distribution grids is enclosed between two separator plates, an auxiliary plate and a spacer. There is a peripheral seal.  The auxiliary plate is designed for external feeding and discharge of a cathode gas, whilst the separator plate and the auxiliary plate are prodded with openings for internal feeding/discharge of anode gas. The join of the auxiliary plate and spacer to the separator plate is effected by means of a solder join. The other two seals are effected with a metallic seal, such as a silver wire. In this way a cell stack consisting of at least twenty-five fuel cells produced in this way can be built up using simple components obtained, for example, from sheet by punching. The invention is preferably carried out with the use of internal distribution of the anode gas and external distribution of the cathode gas, as a result of which a compact, safe cell stack is obtained.
Patent CA-2580287-A1 (CA)
Inventor: PANG MARCUS
IPC: H04W4/08
Filed: 2006-01-11
Abstract: A method for organizing and maintaining an ad-hoc network for communication between a plurality of moving devices is disclosed. The method comprises the steps of grouping the plurality of moving devices into at least one local peer group (LPG) , ordering the plurality of devices within each LPG based upon a relative position of each of the plurality of devices within each LPG and assigning a unique identifier for each of the plurality of moving devices, where the unique identifier is based, in part on the LPG that the corresponding moving device is located.
Patent CA-2580665-A1 (CA)
Inventor: ZHANG SHULIN LARRY
IPC: C11D1/66
Filed: 2005-09-14
Abstract: A composition comprises polyol-based fabric care materials, particularly esterified saccharides. The composition further comprises deposition agents, dispersing medium, and optional adjunct ingredients. The compositions of the present invention are used to treat fabrics to provide one or more of the following benefits: fabric softness, wrinkle reduction after drying, ease of ironing, in-wear shape retention, fabric elasticity, fabric tensile strength, fabric tear strength, and color protection. Various products containing the composition and methods for using the composition are also disclosed.
Patent CA-2581910-A1 (CA)
Inventor: HAMILTON EMILY
IPC: A61B5/344
Filed: 2007-03-09
Abstract: A system and apparatus for implementing a user interface for displaying uterine contraction information is provided. The graphical user interface displays first information conveying a rate of uterine contractions, the first information being derived at least in part on the basis of at least a portion of a contraction signal. The graphical user interface also displays, concurrently with the first information, second information conveying a threshold rate of uterine contractions. In specific examples of implementation, the graphical user interface is adapted for selectively causing an alarm event based at least in part on a rate of uterine contractions conveyed by the first information and the threshold rate of uterine contractions.
Patent CA-2583322-A1 (CA)
Title: Processes for preparing optically active (s or r)-b-amino acid and optically active (r or s)-b-amino acid ester, and b-amino acid 2-alkoxyethyl ester and optically active (s or r)-b-amino acid 2-alkoxyethyl ester
Inventor: MIYATA HIROYUKI
IPC: C07C227/18
Filed: 2005-10-11
Abstract: The present invention relates to a process for preparing an optically active (S or R)-²-amino acid represented by the formula (II):   
wherein R represents an alkyl group, alkenyl group, alkynyl group, cycloalkyl group, aralkyl group, aryl group or heteroaryl group each of which may have a substituent(s), and * represents an asymmetric carbon atom, 
and an optically active (R or S)-²-amino acid ester represented by the formula (III):   
wherein R has the same meaning as defined above, R 1  represents an alkyl group which may have a substituent(s), and * represents an asymmetric carbon atom, provided that it has a reverse absolute configuration to that of the compound of the formula (II), 
which comprises selectively hydrolyzingwater and one of enantiomers of a ²-amino acid ester represented by the formula (I):   
wherein R and R 1  have the same meanings as defined above, 
which is a racemic mixture, in the presence of a hydrolase in an organic solvent.
Patent CA-2584138-A1 (CA)
Title: Methods and compositions for treatment of free radical injury
Inventor: LEE RAPHAEL C
IPC: A61K31/195
Filed: 2005-10-18
Abstract: Therapeutic methods and compositions useful for the prevention and/or treatment of cellular membrane damage leading to or resulting from peroxidation of the cellular membrane and a breakdown of the barrier function of the cellular membrane. A therapeutic composition includes a combination of a membrane sealing sealing surfactant and a cofactor treatment consisting of an antioxidant and a cellular energy store. To affect this goal, the permeability of damaged cellular membranes is reestablished by the membrane sealing surfactant, effectively ~sealing~ the injured membranes. To facilitate rapid tissue recovery, cellular energy levels can be reestablished through addition of a cellular energy source such as, for example, MgCl2-ATP which, serves a further dual benefit of improving the cellular ion balance. Addition of an antioxidant eliminates the generation of Reactive Oxygen intermediates and enhances the metabolism of free radicals.
Patent CA-2585423-A1 (CA)
Inventor: ZELDIS JEROME B
IPC: A61K31/4035
Filed: 2005-10-26
Abstract: Methods of treating, preventing and/or managing a central nervous system injury/damage and related syndromes are disclosed. Specific methods encompass the administration of a PDE4 modulator alone or in combination with a second active agent. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.
Patent CA-2587420-A1 (CA)
Title: Method for reducing the amount of sulfur pick-up by hydrocarbon streams transported through a pipeline
Inventor: FEIMER JOSEPH L
IPC: C10G75/02
Filed: 2005-11-30
Abstract: A process for reducing the level of elemental sulfur and organic sulfur pick~up by refined hydrocarbon streams such as gasoline, diesel, jet fuel, kerosene or fuel additives such as ethers or iso-octane that are transported through a pipeline used to transport various sulfur-containing petroleum streams. The oxygen level in the hydrocarbon stream of interest to be pipelined as well as in at least the first hydrocarbon stream sequenced immediately ahead of the hydrocarbon stream of interest is reduced.
Patent CA-2588388-A1 (CA)
Title: Systems, devices and methods of treatment of intervertebral disorders
Inventor: LOTZ JEFFREY C
IPC: A61F2/44
Filed: 2005-12-01
Abstract: A bioactive/biodegradable nucleus implant for repairing degenerated intervertebral discs that is inflated inside the nucleus space after the degenerated nucleus has been removed to re-pressurize the nuclear space within the intervertebral disc. The implant is inflated with a high molecular weight fluid, gel or combination of fluid and elastomer, preferably an under-hydrated HA hydrogel/growth factor mixture with or without host cells. The implant includes an internal, integral, self-sealing valve that allows one-way filling of the implant after it is placed within the disc, and is made from a material that allows fibrous in growth thereby stabilizing the implant. A variety of substances can be incorporated into the implant to promote healing, prevent infection, or arrest pain.
Patent CA-2589044-A1 (CA)
Inventor: TAYLOR REBECCA ANN
IPC: A61Q19/08
Filed: 2006-02-03
Abstract: A rinsable personal care composition includes (a) 0 to 75 weight percent of a composition surfactant; (b) 0.01 to 99 weight percent of a skin benefit agent or emollient; (c) 0.01 to 20 weight percent of a hydrophobically modified non-platelet particle; and (d) 0 to 99 % water.
Patent CA-2590957-A1 (CA)
Title: 4-aminopiperidine derivatives
Inventor: KUHN BERND
IPC: C07D211/58
Filed: 2005-12-12
Abstract: The present invention relates to compounds of the formula (I), wherein R1 and R2 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/ or prophylaxis of diseases which are associated with DPP-IV, such as diabetes, non-insulin dependent diabetes mellitus and/or impaired glucose tolerance, obesity, and/or metabolic syndrome or ~-cell protection.
Patent CA-2591328-A1 (CA)
Inventor: KIM NAM-PYONG
IPC: H01T13/32
Filed: 2005-11-23
Abstract: A spark plug comprises: a spark plug housing; an axial core electrode disposed in a longitudinal direction in the spark plug housing; and a ground electrode having a terminal part spaced apart along the longitudinal direction from a distal end of the axial core electrode and disposed in a perpendicular relation with the axial core electrode, the terminal part having a circular through hole formed along an axis coaxial with the axial core electrode, the circular through hole having a tapered inner surface and including a plurality of spiral protrusions disposed on the tapered inner surface to induce a turbulent air flow in the combustion inflow.
Patent CA-2592670-A1 (CA)
Title: Backwash strainer having a cyclonic flow mechanism
Inventor: AMAROSA VINCENT A
IPC: B01D29/68
Filed: 2007-06-29
Abstract: A backwash strainer, comprising a generally cylindrical filter element that defines an interior chamber having an inlet through which liquid to be filtered can flow; a backwash arm rotatably mounted within said interior chamber of said filter element; and means positioned proximal said inlet for imparting cyclonic flow to liquid flowing therethrough.
Patent CA-2593111-A1 (CA)
Title: Formulations for coated microprojections having controlled solubility
Inventor: AMERI MAHMOUD
IPC: A61K9/28
Filed: 2006-01-11
Abstract: The invention provides for a formulation for coating one or more microprojections using a non- volatile counterion to improve solubility of a biologically active agent. The invention also includes formulations having a volatile counterion to reduce the solubility of a portion of the biologically active agent.
Patent CA-2596025-A1 (CA)
Inventor: HOJJAT NASRIN
IPC: H01Q19/30
Filed: 2007-08-02
Abstract: A double-sided PCB monopole Yagi-Uda antenna is disclosed, preferably as part of a directional beam antenna comprising a plurality of such antennas vertically mounted in spoke-like fashion around a metallic antenna PCB substrate. The monopoles are printed on a monopole dielectric substrate. Each antenna comprises a driver, a reflector and a pair of directors, each forming a strip etched at corresponding positions on either side of the PCB and electrically connected at a distal end of the strip by a via passing through the PCB. The driver is connected to the central conductor of a connector, while the reflector and directors are grounded. Because the monopoles are printed on a double-sided PCB, there is no bias in the azimuth pattern of antenna when vertically mounted as contemplated above. The use of a monopole dielectric substrate provides generally more consistent and improved performance over discrete wire monopole Yagi-Uda antennas.
Patent CA-2596561-A1 (CA)
Title: Methode et dispositifs d'execution d'une decision sur une carte
Inventor: WAMSLEY ROBERT
IPC: H04L9/32
Filed: 2007-08-08
Abstract: On propose une méthode et des dispositifs dexécution dune décision daccès dans un réseau à accès sécurisé. Les décisions daccès sont effectuées par un authentifiant portatif qui utilise des données et des algorithmes stockés dans lauthentifiant. Des décisions daccès SIM sont effectuées par deux hôtes non en réseau dauthentifiants portatifs ou des cartes locales peuvent être utilisées qui nont pas nécessairement besoin dêtre connectées à un contrôleur ou une base de données daccès central, réduisant ainsi le coût de construire et de maintenir un réseau Amass protégé.
Patent CA-2596853-A1 (CA)
Inventor: CHUP GREGORY
IPC: G11B33/04
Filed: 2006-01-13
Abstract: A container for recording media, such as disk(s), comprising first and second essentially identical trays, each tray being adapted to releasably receive a disk for protective storage. The trays are oriented in overlying and registered relationship to one another and affixed to one surface of a sheet, such as paperboard, in side- by-side relationship, the trays being spaced apart from one another on the sheet to define a spline area of the sheet between the adjacent sides of the trays. Each tray includes unique respective male and female latch means for releasably securing the trays in a closed attitude.
Patent CA-2599263-A1 (CA)
Inventor: KUCHAR GEORGE J
IPC: A01F12/44
Filed: 2007-08-13
Abstract: A concave which has axially extending members and circumferentially extending members. Each of these members has a flat interior surface presented toward the rotor. The flat surfaces of the axially extending members are in the same circular surface as the circumferentially extending members. This presents a smooth grid surface which faces the rotor. The axially extending members have a progressively larger spacing for the first portion of their section. Beginning with the greatest spacing toward the direction material enters the concave and an increasingly smaller spacing away from the opening until they reach a uniform spacing for the remainder of the concave unit.
Patent CA-2599437-A1 (CA)
Title: Volatile liquid dissemination apparatus
Inventor: NAISH GUY EDWARD
IPC: A01M1/20
Filed: 2006-04-25
Abstract: An apparatus adapted to disseminate volatile liquid, such as an insecticide or a fragrance, into an atmosphere, the apparatus comprising a reservoir containing volatile liquid and a liquid transfer member adapted to have contact with both liquid and atmosphere, the transfer member being slideable within a liquid-impermeable sleeve and having a liquid-impermeable lower end, the liquid-impermeable lower end and liquid-impermeable sleeve combining, when the transfer member is in a raised position, to deny access of the liquid to the transfer member, the transfer member being held in the raised position by suitable releasable locking means that, when released, allows the transfer member to be moved with respect to the sleeve to a lowered position in liquid transfer contact with the liquid. The apparatus is convenient to use and leakproof, and it permits liquid dissemination to be stopped and started at will.
Patent CA-2601714-A1 (CA)
Inventor: DAY JONATHAN
IPC: A61B19/04
Filed: 2006-02-21
Abstract: A glove comprises a hand portion 1 and a wrist portion 2 extending from the hand portion 1 and terminates in a hand insertion opening 3. The wrist portion 2 includes anti-roll down means in the form of a band of adhesive material 4 provided on a surface which, in use, will form the inside of the glove, whereby, in use, the adhesive portion 4 may be pressed against the cuff of a garment worn by the user so as to adhere the wrist portion of the glove thereto, thereby preventing roll-down of the glove.
Patent CA-2602035-A1 (CA)
Title: Framework-shuffling of antibodies
Inventor: WU HERREN
IPC: C07H21/04
Filed: 2006-03-17
Abstract: The present invention relates to methods of reengineering or reshaping antibodies to reduce the immunogenicity of the antibodies, while maintaining the immunospecificity of the antibodies for an antigen. In particular, the present invention provides methods of producing antibodies immunospecific for an antigen by synthesizing a combinatorial library comprising complementarity determining regions (CDRs) from a donor antibody fused in frame to framework regions from a sub-bank of framework regions. The invention also provides method of producing improved humanized antibodies. The present invention also provides antibodies produced by the methods of the invention.