baber/WOPTO huggingface dataset:
Patent CO-5611111-A2 (CO)
Title: Inhibidores de la histona desacetilasa
Inventor: STOKES ELAINE SOPHIE ELIZABETH
IPC: C07D417/12
Filed: 2004-10-26
Abstract: 1.- Un compuesto de la fórmula (I) en donde: Anillo A es un heterociclilo, en donde si dicho heterociclilo contiene una fracción -NH-, ese nitrógeno puede sustituirse de manera opcional por un grupo seleccionado de G; R1 es un sustituyente en carbono y se selecciona de halo, nitro, ciano, hidroxi, oxo, trifluorometilo, trifluorometoxi, amino, carboxi, carbamoilo, mercapto, sulfamoilo, C1-6alquilo, C2-6alquenilo, C2-6alquinilo, C1-6alcoxi, C1-6aIcanoilo, C1-6aIcanoiloxi, N-(C1-6alquil)amino, N,N-(C1-6alquil)2amino, C1-6alcanoilamino, N-(C1-6alquil)carbamoilo, N,N-(C1-6alquil)2carbamoilo, C1-6alquiIS(O)a en donde a es 0 a 2, C1-6aIcoxicarbonilo, N-(C1-6alquil)sulfamoilo, N,N-(C1-6alquil)2sulfamoilo, arilo, ariloxi, ariIC1-6alquilo, grupo heterocíclico, (grupo heterocíclico)C1-6alquilo un grupo (D-E-); en donde RAND#39, incluido el grupo (D-E-), puede sustituirse en forma opcional por uno o más V; y en donde, si dicho grupo heterocíclico contiene una fracción -NH-, ese nitrógeno puede sustituirse de manera opcional por un grupo seleccionado de J; V es halo, nitro, ciano, hidroxi, oxo, trifluorometilo, trifluorometoxi, amino, carboxi, carbamoilo, mercapto, sulfamoilo, C1-6alquilo, C2-6alquenilo, C2-6alquinilo, C1-6aIcoxi, C1-6alcanoilo, C1-6alcanoiloxi, N-C1-6alquil)amino, N,N-(C1-6alquil)2amino, C1-6aIcanoilamino, N-(C1-6alquil)carbamoilo, N,N-(C1-6alquil)2carbamoilo, C1-6alquiIS(O)a en donde a es 0 a 2, C1-6aIcoxicarbonilo, N-(C1-6alquil)sulfamoilo, N,N-(C1-6alquil)2sulfamoilo o un grupo (DAND#39-EAND#39-); en donde V, incluido el grupo (DAND#39EAND#39-), puede sustituirse en forma opcional por uno o más W;W y Z se seleccionan independientemente de halo, nitro, ciano, hidroxi, oxo, trifluorometilo, trifluorometoxi, amino, carboxi, carbamoilo, mercapto, sulfamoilo, C1-6alquilo, C2-6alquenilo, C2-6alquinilo, C1-6aIcoxi, C1-6aIcanoilo, C1-6alcanoiloxi, N-(C1-6alquil)amino, N,N-(C1-6alquil)2amino, C1-6aIcanoilamino, N-(C1-6alquil)carbamoilo, N,N-(C1-6alquil)2carbamoilo, C1-6alquiIS(O)a en donde a es 0 a 2, C1-6aIcoxicarbonilo, N-(C1-6alquil)sulfamoilo o N,N-(C1-6alquil)2sulfamoilo; ...
Patent CO-6170350-A2 (CO)
Title: Papel de seguridad o papel especial que incorpora elementos sinteticos de alta resistencia y procedimiento para obtencion de dichos papeles
Inventor: GARCIA JUEZ VICENTE
IPC: B44F1/12
Filed: 2008-12-02
Abstract: 1.- Papel de seguridad o papel especial que incorpora elementos sintéticos de alta resistencia dotados de características visibles a simple vista o bajo particulares condiciones y/o con detectores "ad hoc", caracterizado porque los pigmentos se incluyen en la masa del propio elemento sintético durante su fabricación, confiriéndole las propiedades del pigmento a los elementos sintéticos y siendo el elemento sintético el protector de los pigmentos al ataque de agentes físicos y químicos y al efecto perjudicial de la presentando una larga permanencia a lo largo del tiempo.2.- Procedimiento de fabricación de papel de seguridad o papel especial que incorpora elementos sintéticos de alta resistencia dotados de características visibles a simple vista o bajo particulares condiciones, tal y como se define en la reivindicación 1, caracterizado porque los elementos sintéticos se preparan previamente a su introducción en el procedimiento de fabricación de papel mediante una dispersión acuosa de los mismos en presencia de agentes dispersantes y/o penetrantes y/o antiespumantes. 3.- Procedimiento de fabricación de papel de seguridad o papel especial según la reivindicación 2 caracterizado porque la dispersión de elementos de seguridad se incorpora homogéneamente en la masa del papel durante el proceso de formación del mismo. 4.- Procedimiento de fabricación de papel de seguridad o papel especial según la reivindicación 2 caracterizado porque la dispersión de elementos de seguridad se incorpora de forma controlada en la masa de papel, formando bandas o zonas donde se acumulan tales elementos sintéticos.
Patent CO-6251248-A2 (CO)
Title: Compuestos de tiazolopiridina como moduladores de sirtuina
Inventor: BEMIS JEAN
IPC: A61K31/437
Filed: 2010-01-08
Abstract: 1.- Se reivindica compuesto representado por la fórmula estructura (II):o una sal de éste, en donde: dos de X1 a X4 se seleccionan de -CR*- y -N-; los otros dos de X1 a X4 son -CR*-;R* es independientemente seleccionado en cada presencia de -H, alquilo inferior o halógeno; R1 es un grupo de solubilización; y R2 se selecciona de fenilo opcionalmente sustituido con uno o más sustituyentes independientemente seleccionados de -CN, -F, -CI y -CF3, y cuando cada uno de X1 a X4 es CR*-, R2 se selecciona adicionalmente de un heterociclo de 5 a 6 miembros que contiene un heteroátomo N y, opcionalmente, un segundo heteroátomo seleccionado de N, O o S, en donde dicho heterociclo está opcionalmente sustituido con metilo. 2.- El compuesto de la Reivindicación 1 en donde: X1 a X4 es CR*-; y R2 se selecciona de fenilo, fluorofenilo, difluorofenilo, clorofenilo, metiltiazolilo, pirimidinilo, piridilo y pirazolilo. 3.- El compuesto de la Reivindicación 2, en donde R2 se selecciona de fenilo, fluorofenilo, difluorofenilo, clorofenilo, 2-metiltiazol-4-ilo, piridilo y pirazol-1-ilo. 4.- El compuesto de la Reivindicación 3, donde R2, es fenilo o piridilo. 5.- El compuesto de la Reivindicación 1, en donde uno de X1 a X4 son -N-. 6.- El compuesto de la Reivindicación 1, en donde uno de X1 a X4 son -N-. 7.- El compuesto de la Reivindicación 5, en donde X1 es N. 8.- El compuesto de la Reivindicación 6, en donde X1 a X2 son -N-. 9.- El compuesto de la Reivindicación 6, en donde X1 y X4 son -N-. 10.- El compuesto de cualquiera de las Reivindicaciones 1 a 9, en donde: R1 es -CH2-R3; y R3 es un heterociclo que contiene nitrógeno opcionalmente sustituido con uno o más sustituyentes seleccionados de alquilo C1-C4, amino, halógeno, metoxi y metoxi-alquilo C1-C4.
Patent CO-6361915-A2 (CO)
Title: Composición farmacéutica sólida que comprende amlodipina y losartan
Inventor: WOO JONG SOO
IPC: A61K31/44
Filed: 2011-08-19
Abstract: La presente invención se relaciona con una composición farmacéutica sólida para la prevención o tratamiento de desórdenes cardiovasculares que comprenden amlodipina y losartan como ingredientes activos, y un desintegrante el cual es una mezcla de por lo menos dos componentes seleccionados del grupo consistente de glicolato de almidón de sodio, sodio de crucecarmelosa, y crucepovidona, las cuales exhiben un nivel alto y estable de tasas de disolución de amlodipina y el losartan.
Patent CO-6501173-A2 (CO)
Title: Aparato transportador y método de transporte continuo de red permeable al aire
Inventor: YAMAMOTO HIROKI
IPC: A61F13/15
Filed: 2011-09-30
Abstract: En un aparato transportador (100), una cinta (110) está provista con una pluralidad de porciones de succión (111) que penetran en la cinta (110). La cinta (110) incluye porciones elevadoras (113) cada una de las cuales está provista entre las porciones de succión (111) adyacentes en una dirección cruzada (CD) y se elevan de las porciones de borde (112) que forman las porciones de succión (111). La pluralidad de porciones de succión (111) adyacentes entre sí a través de las porciones elevadoras (113) se comunican entre sí, cuando una red (7) es succionada y retenida sobre la cinta (110). Las porciones de succión (111) ubicadas en porciones más terminales (110A) en la dirección cruzada (CD) de la cinta (110) se comunican con el exterior, cuando la red (7) es succionada y retenida sobre la cinta (110).
Patent CO-6470846-A2 (CO)
Title: Derivados aminobut´ricos sustituidos como inhibidores de neprilisina
Inventor: COPPOLA GARY MARK
IPC: C07C233/45
Filed: 2011-11-30
Abstract: La presente invención proporciona un compuesto de la fórmula (I'):o una sal farmacéuticamente aceptable del mismo, en donde R1, R2, R3, X y n se definen en la presente. La invención también se refiere a un método para la elaboración de los compuestos de la invención, y a sus usos terapéuticos. La presente invención proporciona además una combinación de agentes farmacológicamente activos y una composición farmacéutica.
Patent CO-6561768-A2 (CO)
Title: Proteinas de dominio de armazon basadas en fibronectina que se unen a la proteina convertasa subtilisina kexina tipo q (pcsk9)
Inventor: CAMPHAUSEN RAY
IPC: A61K38/39
Filed: 2012-10-29
Abstract: La presente invención se refiere a proteínas de dominio de armazón basadas en fibronectina que se unen a PCSK9. La invención también se refiere al uso de las proteínas innovadoras en aplicaciones terapéuticas para tratar aterosclerosis, hipercolesterolemia y otras enfermedades relacionadas con el colesterol. La invención se refiere además a células que comprenden tales proteínas, polinucleótidos que codifican tales proteínas o fragmentos de las mismas y a vectores que comprenden los polinucleótidos que codifican la proteína innovadora.
Patent CO-6660512-A2 (CO)
Title: Proceso para fabricar composiciones hemostáticas secas y estables
Inventor: GOESSL ANDREAS
IPC: A61K9/14
Filed: 2012-12-28
Abstract: Se describe un proceso para fabricar una composición hemostásica seca y estable, comprendiendo el citado proceso a) proporcionar una preparación granular seca de un polímero biocompatible, apropiado para uso en hemostasia, b) recubrir los gránulos en la citada preparación granular seca con una preparación de un agente que induce coagulación, obteniendo en esa forma gránulos de polímero recubiertos con un agente que induce coagulación, c) cargar los citados gránulos de polímero recubiertos con un agente, que induce coagulación, en un recipiente final, d) terminar el recipiente final en un dispositivo farmacéutico almacenable que contiene los citados gránulos de polímero recubiertos con un agente, que induce coagulación, como una composición hemostásica seca y estable.
Patent CO-6781506-A2 (CO)
Title: Uso del agonista de receptor tipo toll para el tratamiento del cáncer
Inventor: GLEIBERMAN ANATOLI
IPC: A61K39/00
Filed: 2013-07-29
Abstract: La presente invención se refiere a métodos y agentes utilizados para tratar el cáncer en tejidos que expresan el receptor Tipo Toll 5, mediante la proporción de un agonista del receptor Tipo Toll tal como flagelina. La presente invención se refiere también a la protección del hígado de una toxicidad hepática utilizando un agonista del receptor Tipo Toll.
Patent EP-1022136-A2 (EP)
Inventor: MOTZKE MICHAEL
IPC: B41F23/02
Filed: 2000-01-07
Abstract: The system is designed so that the cooling off zones (5) of the drier (1) contains a moistening unit (8), serving for remoistening and cooling of the paper web (2). The spray nozzles (10) of which is suppliable with an amount of liquid exceeding the remoistening liquid amount.
Patent EP-1025765-A2 (EP)
Inventor: SCHNEIDER OTMAR
IPC: A41D31/00
Filed: 2000-01-28
Abstract: The outside of the material (1) has a knitted outer layer (7). The layer (7) consists of a first fiber yarn made of flameproof materials with the properties of meta-aramid, and of a second fiber yarn made of flame-resistant materials with the properties of para-aramid
Patent EP-1046562-A2 (EP)
Inventor: ROCQUET STEPHANE
IPC: F16D25/08
Filed: 2000-04-08
Abstract: A fluid pressure operated actuating cylinder (10) for mounting in an aperture (13) in a wall
(14) of vehicle. The cylinder a body having first abutments (17, 18) with first locating
surfaces (17a, 21a) facing in a first direction and second deflectable abutments (19) which act
as first snap connectors and are axially spaced from the first abutments and have second
locating surfaces (19a) facing in a second direction generally opposed to said first direction.
The first and second locating surfaces are arranged to contact respective first and second
oppositely directed surfaces (14a, 14b) of the wall (14) after insertion of the cylinder (10)
through the aperture (13) and deflection of the second abutment (19) to locate the cylinder in
the aperture. The abutment means may be formed integrally with the cylinder or on a separate
sleeve (12) which encircles the cylinder and is snap connected thereto.
Patent EP-1053690-A2 (EP)
Inventor: DECKWART SIEGFRIED
IPC: A23L13/60
Filed: 2000-05-17
Abstract: A food product, comprising a shaped meat, sausage, cheese, fish or vegetable core with a spherical biscuit covering, is new. A food product comprises a shaped meat, sausage, cheese, fish or vegetable core encased by a biscuit covering to form a spherical product. The core may have a cube (4-20 mm side length), round (4-20 mm diameter) or oval (8-50 mm length and 4-20 mm diameter) shape. The covering is 1-5 mm thick and is coated with a seasoning, aromatic and/or colored garnishing or both the core and the covering may contain functional food ingredients, e.g. omega-3-fatty acids, prebiotic fillers, multi-vitamin additives and trace bulk element additives, as well as aromatic components.
Patent EP-1088779-A2 (EP)
Inventor: CRAMER DIRK DIPL-ING
IPC: B65H18/20
Filed: 2000-08-31
Abstract: The method involves pressing the reel (6') into the winding bed (11) with a load roller (7) and supporting it in the winding bed on a cushion of compressed air with a minimum load of 0.5 kN/m during the entire spooling process. The compressed air cushion is controlled depending on the load on the load roller and the load roller is used to determine the diameter of the reel.
Patent EP-1126648-A2 (EP)
Title: Equipment, transponder and methods for optical fiber transmission
Inventor: KIKUCHI NOBUHIKO
IPC: H04L25/14
Filed: 2000-09-15
Abstract: The technical problem disclosed concerns increase of
transmission distance between inter-site transmission
parts when a circuit speed is increased, and
simplification of an intra-site circuit. 
     The means to resolve the problem is as follows.
An intra-site circuit (142-1) connecting an intra-site
information communications device (140-1) and a
wavelength division multiplexing optical transmission
device (147) is demultiplexed into plural low speed
wavelength division multiplexing signals by a transponder
(100) according to this invention, and transmitted to an
inter-site optical fiber circuit (144). The signals are
again multiplexed into a high speed optical signal by a
transponder (110) in a wavelength division multiplexing
optical transmission device (148) on the receiving side,
and transmitted to an intra-site optical fiber circuit
(143-1).
Patent EP-1094340-A2 (EP)
Inventor: NAKAMURA KAZUHIRO
IPC: G02B1/11
Filed: 2000-09-28
Abstract: There is disclosed an anti-glare and anti-reflection
film, which has a transparent support, and at least one
low-refractive-index layer that comprises a fluorine-containing
resin and has a refractive index in the range
from 1.38 to 1.49, wherein the film comprises an anti-glare
layer that is disposed between the support and the
low-refractive-index layer and that contains a binder
having a refractive index in the range from 1.57 to 2.00.
The anti-glare and anti-reflection film, which has
sufficient anti-reflection property, resistance to damage,
and stain-proofing property, and free from uneven color,
can be produced simply and inexpensive manner. There is
also disclosed a polarizing plate and an image display
device, each utilizing the anti-glare and anti-reflection
film.
Patent EP-1093256-A2 (EP)
Title: Method and apparatus for generic frame relay services support in a communication network
Inventor: SYED SHARFUDDIN
IPC: H04Q11/04
Filed: 2000-10-12
Abstract: A method and apparatus for generic support of frame relay services in a
communications network is presented. This is accomplished by defining a bit field that
indicates whether or not particular functions or services (including frame relay services)
are supported by a particular node or other network component. The bit field for each
component within the communications network is communicated to the network
manager, which stores the bit fields for each component within a database. The database
is then utilized to perform network management functions, as it informs the network
manager whether a particular service/feature is available on the network component to
which the bit field corresponds.
Patent EP-1099873-A2 (EP)
Inventor: FISCHER JOERG
IPC: B60T13/74
Filed: 2000-11-04
Abstract: The cylinder (1) has an electromechanically actuated brake actuator (2) with which a brake lining can be pressed onto a brake body that is to be braked. The spring storage brake cylinder (9) and the electrically actuated brake actuator have mutually coaxial brake rods (7,8) with which the brake lining can be pressed against the brake body. Independent claims are also included for the following: a braking device for a commercial vehicle with two mutually independent working brake circuits.
Patent EP-1099843-A2 (EP)
Inventor: ISOBE TAKASHI
IPC: F02D43/00
Filed: 2000-11-08
Abstract: A control system is disclosed that accelerates the rise in
temperature of a catalyst provided in an exhaust system of an internal
combustion engine. The system increases the intake air amount after
the engine starts and retards the ignition timing according to a
rotational speed of the engine. In this control system, a failure of the
catalyst temperature rise acceleration control is diagnosed according to
the engine rotational speed and/or a retard amount of the ignition timing
during the execution of the catalyst temperature rise acceleration control.
The above failure may also be diagnosed according to at least one of the
ignition timing and the engine rotational speed when decreasing the
intake air amount during the execution of the catalyst temperature rise
acceleration control. The above failure may also be diagnosed according
to a detected catalyst temperature and an estimated catalyst
temperature.
Patent EP-1107457-A2 (EP)
Inventor: HARADA HIROTAKA
IPC: H03L7/093
Filed: 2000-11-29
Abstract: There is provided a method of synchronizing a phase-locked
loop (PLL) which is capable of reducing an area occupied by the
PLL in a chip of the semiconductor device and shortening a lock-up
time even when a band of an oscillation frequency is wide and a
changeable range of a multiplying factor is wide. 
     The method for synchronizing the PLL includes a step of
smoothing, by using a low pass filter (14), a control current (I C )
flowing in or out from a charge pump (13, 31, 51, 61) in accordance
with an up-clock/UCK or a down-clock DCK to be fed from a phase
frequency comparator (11) to output it as a control voltage, a
step of oscillating an internal clock (CK I ), by using a voltage
controlled oscillator (15), having number of oscillation
frequencies corresponding to a control voltage in an oscillation
frequency band decided in accordance with oscillation frequency
band setting data (DT F ), a step of dividing, using a frequency
divider (16), a frequency of the internal clock (CK I ) at a rate
of frequency division decided in accordance with multiplying
factor setting data (DT D ) to output it as a frequency-divided clock
and a step of changing a value of the control current (I C ) in
accordance with oscillation frequency band setting data (DT F ) and
with multiplying factor setting data (DT D ).
Patent EP-1022522-A2 (EP)
Inventor: GARCIA ALEJANDRO R
IPC: F25B15/00
Filed: 2000-01-05
Abstract: An absorption air conditioning machine that includes a main machine section
containing an evaporator unit (13), an absorber unit (14), at least one generator unit (22,25), a
condenser unit (30), and at least one solution heat exchanger (20,24). The heat exchanger tubes
of the units and the solution heat exchanger are all supported within a pair of spaced
apart tube sheets (50,51) to provide a highly compact machine assembly.
Patent EP-1020110-A2 (EP)
Inventor: KONIJN JAN LEENDERT
IPC: A01G23/04
Filed: 2000-01-13
Abstract: Device for packing rootballs (24) of small trees (23), bushes and
similar rootballs into packing wire gauze (25), said device being
provided with a packing wire gauze supply, or being intended
for use in combination with a packing wire gauze (25) feeding
device, and in which the device is further provided with a
gripping member (15) for grasping the small trees (23), an arc-shaped
first guide (2) for moving the gripping member to and fro in a
curve, a second guide (4) or second guides being approximately
perpendicular to the first guide, for moving said gripping
member (15) up and down.
Patent EP-1101940-A2 (EP)
Inventor: MAASS MARTIN
IPC: F04B49/24
Filed: 2000-11-15
Abstract: A high pressure piston pump (16,40) includes a housing having a low pressure
fuel inlet (44) and a high pressure fuel outlet; at least two pistons (48) disposed in the
housing; a driveshaft (50) for supplying power to drive the at least two pistons; and a
bypass valve (52) fluidly connected to at least one of the at least two pistons to
deactivate the at least one piston. A method of varying the flow output of a high
pressure piston pump having at least two pistons includes deactivating at least
one of the two pistons by directing fluid displaced by the at least one piston to a
bypass valve.
Patent EP-1030503-A2 (EP)
Inventor: BRUSILOVSKY ALEC
IPC: H04M11/00
Filed: 2000-02-09
Abstract: PSTN Internet Notification (PIN) services that can be provided as part of
interconnecting IP and Public Switched Telephone Network (PSTN) systems with the
intent of converging existing and creating new hybrid PSTN and IP services. PSTN
Events Notification, based on well-defined PIN protocols, will promote
interoperability of both the networks and systems built by different vendors.
Patent EP-1043908-A2 (EP)
Inventor: CHEN TSAO-TSEN
IPC: H04W72/08
Filed: 2000-03-28
Abstract: The invention provides a novel methodology for increasing the performance of
CDMA systems with packet data services by accommodating a variety of users with
different rates. The invention operates to increase the spectrum efficiency of a wireless
system by using an optimal transmission set of base transceiver stations and assigning
proper data rates to efficiently utilize the radio resources. In particular, the invention
operates to decrease interference so that the quality of data transmission in CDMA
systems is advantageously maintained. Moreover, the invention operates to increase the
allocation of bandwidth, particularly for high-speed data services. The invention
provides a methodology to evaluate the data rates of different combinations of BTSs that
may be in connection with a particular mobile station (MS), allocate an appropriate data
rate for the MS and make allocation of system resources more efficient in a multi-user
environment.
Patent EP-1081247-A2 (EP)
Inventor: OKAZAKI NAOTO
IPC: H01L21/203
Filed: 2000-08-18
Abstract: An arc type ion plating apparatus has a holder for holding
substrates. The holder is provided in a vacuum vessel. One
end portion of a bent transport tube is connected to this vacuum
vessel so as to face the substrates on the holder. The transport
tube has a rectangular or elliptical sectional shape. A
plurality of arc evaporation sources are arranged in a
longitudinal direction Y on the other end portion of the
transport tube. The respective arc evaporation sources melt
cathodes by vacuum arc discharge so as to generate plasma
containing cathode material. Magnetic coils for forming a
magnetic field bent along the transport tube are provided on
the outer circumferential portion of the transport tube. The
plasma generated by the arc evaporation sources is introduced
by the magnetic field into the vicinities of the substrates in
the vacuum vessel.
Patent EP-1145018-A2 (EP)
Inventor: HOLT ALYN R
IPC: G01R31/26
Filed: 2000-01-12
Abstract: A system is useful for positioning a load, such as a test head (802). The system includes an arm which supports the load and which moves along a first vertical axis. The system also includes a rotation unit for rotating the first vertical axis (734) spaced apart from the first vertical axis.