baber/WOPTO huggingface dataset:
Patent NZ-589732-A (NZ)
Title: A process for the preparation of the apoptosis promoter abt-263
Inventor: FRANCZYK THADDEUS S
IPC: C07D295/155
Filed: 2009-06-18
Abstract: Disclosed A process for making ABT-263 (7) an apoptosis promoter having the proper chemical name: N-(4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohex-1-en-1-yl)methyl)piperazin-1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-((phenylsulfanyl)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide, comprising: (a) reacting 4,4-dimethylcyclohexanone, an alkyl formate and a first base to provide (2E)-2-(hydroxymethylene)-4,4-dimethylcyclohexanone and isolating or not isolating the (2E)-2-(hydroxymethylene)-4,4-dimethylcyclohexanone; (b) reacting the (2E)-2-(hydroxymethylene)-4,4-dimethylcyclohexanone, a second base and a first silyl ether protecting group reagent to provide a first protected (2E)-2-(hydroxymethylene)-4,4-dimethylcyclohexanone and isolating or not isolating the first protected (2E)-2-(hydroxymethylene)-4,4-dimethylcyclohexanone; (c) reacting the first protected (2E)-2-(hydroxymethylene)-4,4-dimethylcyclohexanone and 4-chlorophenyl magnesium bromide to provide the first protected (2E)-1-(4-chlorophenyl)-2-(hydroxymethylene)-4,4-dimethylcyclohexanol; and isolating or not isolating the first protected (2E)-1-(4-chlorophenyl)-2-(hydroxymethylene)4,4-dimethylcyclohexanol; and (d) reacting the first protected (2E)-1-(4-chlorophenyl)-2-(hydroxymethylene)-4,4-dimethylcyclohexanol and a first acid to provide 2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-ene-1-carbaldehyde and isolating or not isolating the 2-(4-chlorophenyl)5,5-dimethylcyclohex-1-ene-1-carbaldehyde; (e) reacting 2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-ene-1-carbaldehyde, ethyl 4-piperazin-1-ylbenzoate and a first reducing agent and isolating or not isolating the ethyl 4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)benzoate; (f) reacting ethyl 4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)benzoate and an aqueous third base, and isolating or not isolating the 4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)benzoic acid; and (g) reacting 4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)benzoic acid, 4-(((1R)-3-morpholin-4-yl-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide, a first coupling reagent, and, optionally; a first auxiliary coupling reagent and isolating or not isolating the N-(4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohex-1-en-1-yl)methyl)piperazin-1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-1- ((phenylsulfanyl)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide.
Patent NZ-592193-A (NZ)
Title: A intraocular lens with two surfaces zone having different surface topologies to prevent sticking
Inventor: DOWNER DAVID A
IPC: A61F2/16
Filed: 2009-10-14
Abstract: Disclosed is an intraocular lens with feature to reduce the adherence of the haptic zone to the optic zone. The lens comprises an optic zone, configured to replace a natural lens or to correct a malady in the natural lens of an eye, having a first surface topology, and a haptic zone, configured to hold the intraocular lens in the eye, having a second surface topology. The second surface topology reduces the ability for the haptic to adhere to the optic zone, by the second surface topology comprises one or more continuous geometry features over the second surface topology. The first surface topology comprises a first surface roughness and the second surface topology comprises a second surface roughness at least two times greater than the first surface roughness. The haptic is configured to hold the intraocular lens in a desired position and orientation, and configured to be folded inside the optic zone as the intraocular lens is compressed for insertion into the eye and wherein the second surface topology of the haptic forms a space between the haptic and the optic zone during insertion of the lens into the eye. The optic zone is configured to unfold in the eye.
Patent NZ-595265-A (NZ)
Title: Amide derivatives as neuropeptide y5 receptor ligands
Inventor: CHEN BIN
IPC: C07D413/12
Filed: 2010-03-19
Abstract: Disclosed herein are compounds of formula I, wherein the substituents are as defined in the specification, processes for their preparation, compositions comprising said compounds and uses thereof. Said compounds are useful as they act as ligands at the neuropeteide Y Y5 receptor and are therefore useful in the treatement of disorders realted to mood, stress, cognition, dementia, schizophrenia, ADHD. Examples of preferred compounds include: trans-4-(2-oxo-pyrrolidin-l-yl)-cyclohexanecarboxylic acid [5-(3, 5-difluoro-phenyl)pyridin-2-yl]-amide; cis-4-(2-oxo-pyrrolidin-l-yl)-cyclohexanecarboxylic acid [5-(3,5-difluoro-phenyl)-pyridin-2-yl]-amide; cis-4-(2-oxo-pyrrolidin-l-yl)cyclohexanecarboxylic acid [5-(3 ,5-dichloro-phenyl )-pyridin-2-yl]-amide; cis-4-(2-oxopyrrolidin-l-yl)-cyclohexanecarboxylic acid [5-(3,5-difluoro-phenyl)-pyrazin-2-yl]-amide; 4-(2-oxo-azetidin-l-yl)-cyclohexanecarboxylic acid [5-(3,5-difluoro-phenyl)-pyridin-2-yl]-amide; cis-4-(2-oxo-piperidin-l-yl)-cyclohexanecarboxylic acid [5-(3,5-difluoro-phenyl)-pyridin-2-yl]-amide; cis-4-(2-oxo-pyrrolidin-l-yl)-cyclohexanecarboxylic acid [5-(3-fluoro-5-methyl-phenyl)-pyridin-2-yl]-amide; CIS- 4-(2-oxo-oxazolidin-3-yl)cyclohexanecarboxylic acid [1-(3,5-difluoro-phenyl)-1H-pyrazol-3-yl]-amide;
Patent NZ-596657-A (NZ)
Title: Self micro-emulsifying oral pharmaceutical composition of hydrophilic drug and preparation method thereof
Inventor: WANG JONG-JING
IPC: A61K9/107
Filed: 2010-04-27
Abstract: 596657 Disclosed herein is an oral self micro-emulsifying pharmaceutical composition which comprises: A therapeutically effective amount of a hydrophilic drug, preferably bendamustine or gemcitabine, or its pharmaceutically acceptable salt; one or more solvents capable of dissolving the hydrophilic drug or its pharmaceutically acceptable salt to form a drug-solvent solution, such as water, glycerol and propylene glycol; a surfactant system comprising one or more surfactants such as polysorbate and oleoyl polyoxyglycerides, said surfactant system exhibiting a hydrophilic-lipophilic balance (HLB) value ranging from about 8 to about 17; and one or more hydrophilic carriers, such as polyethylene glycol, which are compatible with said drug-solvent solution and said surfactant system.
Patent NZ-598020-A (NZ)
Title: Fused thiazolo and oxazolo pyrimidinones
Inventor: CHHIPA LAXMIKANT
IPC: A61K31/519
Filed: 2010-08-31
Abstract: Disclosed is a Compound of formula (I) e.g. [(2-Hydroxy-4-oxo-5,6,7,8-tetrahydro-4H-9-thia-1,4a-diaza-fluorene-3-carbonyl)-amino]acetic acid;their pharmaceutically acceptable salts and their Isomers, stereoisomers, conformers, tautomers, polymorphs, hydrates, and solvates wherein the variables are defined in the specification for treating anemia.
Patent NZ-602658-A (NZ)
Title: Membrane filtration wherein permeate fraction is cooled to lower temperature than retentate fraction
Inventor: HOFFMANN TOM
IPC: A23C9/142
Filed: 2011-03-03
Abstract: A method for processing dairy products by means of membrane filtration, including: subjecting the dairy product to membrane filtration (2) to form a permeate fraction and a retentate fraction; and cooling the permeate fraction (3) to a temperature that is lower than the temperature of the retentate fraction, resulting in a cooling of the membrane surfaces. A membrane filtration assembly for carrying out the method is also disclosed.
Patent NZ-607367-A (NZ)
Title: A method of gasifying carbonaceous material and a gasification system
Inventor: LI CHUN-ZHU
IPC: C10J3/64
Filed: 2011-07-26
Abstract: A method of gasifying carbonaceous material is disclosed, as well as the system (20) and vessel (30) in which the method is performed. The method comprises a first step of pyrolysing and partially gasifying the carbonaceous material to produce volatiles and char. The volatiles and the char are then separated and, subsequently, the char is gasified and the volatiles are reformed. The raw product gas is then finally cleaned with char or char-supported catalysts or other catalysts. The gasification system includes a vessel (21) comprising a reforming zone (25), a char gasification zone (23) and a pyrolysis zone (22). The vessel is arranged such that the reforming zone, the char gasification zone and the pyrolysis zone are substantially separate from another and that following pyrolysis of the carbonaceous material and separating the char and the volaties, the volatiles and the char are directed to the reforming zone and the char gasification zone, respectively .The gasification system further comprises a product gas cleaning zone (catalyst bed 26) that is directly coupled with the vessel and in fluid communication with the reforming zone in an arrangement whereby partially reformed volatiles and/or product gas are passed through the product gas cleaning zone.
Patent NZ-608572-A (NZ)
Title: Maize cytoplasmic male sterility (cms) c-type restorer rf4 gene, molecular markers and their use
Inventor: REN RUIHUA
IPC: C12Q1/68
Filed: 2011-09-26
Abstract: Discloses methods for identifying a plant comprising a functional restorer gene for maize C-type cytoplasmic male sterility or for introducing the maize Rf4-bHLH gene into a host organism where the methods involved identifying a nucleic acid sequence which is tightly linked (within 100kb) of the Rf4 gene.
Patent NZ-610153-A (NZ)
Title: Novel anti-dr5 antibody
Inventor: YOSHIDA HIROKO
IPC: C12P21/08
Filed: 2011-10-27
Abstract: Disclosed is an antibody characterized in that:, a heavy chain sequence contains a variable region having CDRH1, CDRH2, and CDRH3, and the CDRH1 comprises an amino acid sequence represented by SEQ ID NO: 82 (GYFMN), the CDRH2 comprises either one of the amino acid sequences represented by SEQ ID NOS: 83 and 89 (RFNPYNXDTFYNQKFKG), and the CDRH3 comprises an amino acid sequence represented by SEQ ID NO: 84 (SAYYFDSGGYFDY); and, a light chain sequence contains a variable region having CDRL1, CDRL2, and CDRL3, and the CDRL1 comprises anyone of the amino acid sequences represented by SEQ ID NOS: 79, 85, 86, 87, and 88 (RSSQSLVHSNXNTYLH), the CDRL2 comprises an amino acid sequence represented by SEQ ID NO: 80 (KVSNRFS), and the CDRL3 comprises an amino acid sequence represented by SEQ ID NO: 81 (SQSTHVPWT), or a functional fragment of the antibody., Further disclosed are antibodies which compete for binding with said antibodies or which bind the same epitope thereof.
Patent NZ-613637-A (NZ)
Title: Beverage extraction apparatus
Inventor: OKA KITARO
IPC: A47J31/44
Filed: 2011-08-24
Abstract: A beverage extraction apparatus 1 comprising a granule containing part 2 containing granules M for extraction of a beverage, first pouring device 2B for pouring an extraction solvent 4 into the granule containing part from a first direction, and collecting device for collecting an extract liquid extracted by means of the extraction solvent at the side of layers of the granules corresponding to the first direction. The granule containing part 2 is provided with a detachable restraining member 11 for placing the granules for extraction of a beverage in a substantially sealed state.
Patent NZ-614485-A (NZ)
Title: Dispenser
Inventor: SPORRE THORBURN ANNIE
IPC: B65D83/08
Filed: 2011-04-05
Abstract: A dispenser box (200), in particular for interfolded wipes and tissues, which aims to provide improved exposure of information printed on the package while not taking up a large space on a shop shelf or during storage and transport and while allowing efficient stacking. The box (200) has a modified rectangular shape with leaf-shaped end walls (236, 237) and partly curved main walls (250, 251) that may form symmetrically or non- symmetrically configured halves of the dispenser box (200). The first main wall (250) has a substantially flat surface extending from a first side edge (238) of the dispenser box (200) and changing into a curved surface when moving in a direction from the first side edge (238) towards a second side edge (239) of the dispenser box. The second main wall (251) has a corresponding substantially flat surface at the second side edge (239) which changes into a curved surface when moving in a direction towards the first side edge (238).
Patent NZ-622457-A (NZ)
Title: An anti misuse system
Inventor: SHARP GRAHAM
IPC: B65H75/18
Filed: 2011-05-27
Abstract: A roll of sheet material for a sheet dispenser incorporating an end portion (120) shaped for the operation of a complementary retracting portion incorporating an interacting mechanism, the retracting portion being movable between a deployed position in which the interacting mechanism affects the functionality of the sheet dispenser and a retracted position in which the interacting mechanism enables the sheet dispenser to be functional. The end portion comprises a first projection (153) and a second projection (152) radially separated from the first projection. The first projection is dimensioned so as to release the interacting portion upon insertion, and the second projection is arranged to retract the retracting portion upon insertion. The first projection and second projection are concentrically arranged.
Patent NZ-729830-A (NZ)
Title: Matching delayed infusion auto-programs with manually entered infusion programs
Inventor: KOHLBRECHER CHRISTOPHER
IPC: A61M5/00
Filed: 2015-09-15
Abstract: Infusion pumps serve as a useful tool for delivering medication to patients, and are particularly beneficial for their great accuracy in delivering medication at a specific rate and dose. Moreover, medical facilities have enabled hospital caregivers, such as nurses, to deliver medication to patients using auto-programming features available for the infusion pump. Although auto-programming features may reduce errors made manually by hospital caregivers, medical facilities still struggle with identifying and responding to errors made when using an infusion pump. Accordingly, one aspect of the invention relates to a system configured to identify an acceptable manual program, the system comprising: a first computer comprising a computer network interface; and an infusion pump configured to communicated with said first computer using said computer network interface; wherein said first computer is configured to: receive an infusion auto-program from a remote source, wherein said infusion auto-program comprises IV drug container information, infusion pump information, and infusion program settings, determine that said first computer is unable to transmit said infusion auto-program to said infusion pump, queue said infusion auto-program, wherein the queued infusion auto-program becomes a stale auto-program, and send said stale auto-program to said infusion pump when said infusion pump communicates with said first computer; and wherein said infusion pump is configured to: receive a manual infusion program, wherein said manual infusion program comprises one or more of a completed manual infusion program or a running manual infusion program, save and execute said manual infusion program, compare said stale auto-program to said manual infusion program, wherein said comparison is based on one or more factors comprising an approximate time of infusion administration or parameter matching logic comprising infusion parameters, identify potential matches between said stale auto-program and said manual infusion program using the infusion parameters, determine that said potential matches are within a predefined tolerance using one or more configurable rules, continue to execute said manual infusion program on said infusion pump, save differences between said manual infusion program and said stale auto-program, save a first event alert indicating the manual infusion program as an acceptable potential match of said potential matches, and save a second event alert indicating the auto-program as an un-executed program.
Patent NZ-755953-A (NZ)
Title: Folding machine for folding fiber products and stack of fiber products produced thereby
Inventor: WEN-CHENG LIU
IPC: B65B35/50
Filed: 2019-08-01
Abstract: A folding machine for folding fiber with two folding devices working together to increase the folding efficiency of fiber products. The folding device includes a first folding device comprising: a first cutting device for cutting a first fiber product, wherein each of the first fiber product comprises a front end and a back end; a first delivery wheel, the first delivery wheel receiving the cut first fiber product from the first cutting device; a first folding-line wheel adjacent to the first delivery wheel, wherein the first folding-line wheel and the first delivery wheel make a first folding line on the first fiber product at one third of the length of the first fiber product distant from the front end, and the first fiber product between the front end and the first folding line is adhered by the first folding-line wheel; a first platen wheel adjacent to the first delivery wheel and downstream of the first folding-line wheel, wherein the first platen wheel and the first delivery wheel fold the first fiber product along the first folding line; and a first folding wheel adjacent to the first delivery wheel, the first folding wheel receiving the first fiber product from the first delivery wheel ; and a second folding device comprising: a second cutting device for cutting a second fiber product, wherein each of the second fiber product comprises a front end and a back end; a second delivery wheel, the second delivery wheel receiving the cut second fiber product from the second cutting device; a second folding-line wheel adjacent to the second delivery wheel, wherein the second folding-line wheel and the second delivery wheel make a first folding line on the second fiber product at one third of the length of the second fiber product distant from the front end, and the second fiber product between the front end and the first folding line is adhered by the second folding-line wheel; a second platen wheel adjacent to the second delivery wheel and downstream of the second folding-line wheel, wherein the second platen wheel and the second delivery wheel fold the second fiber product along the first folding line; and a second folding wheel adjacent to the second delivery wheel, the second folding wheel receiving the second fiber product from the second delivery wheel, wherein the first folding wheel and the second folding wheel are adjacent and make a second folding line on the first fiber product and the second fiber product passing therethrough and fold the first fiber product and the second fiber product along the second folding line.
Patent NZ-771980-A (NZ)
Title: High spectral efficiency “zero bandwidth modulation process” without side bands
Inventor: AGGARWAL RAKESH
IPC: H04B1/02
Filed: 2019-06-17
Abstract: A method (1000) for transmission of signal, comprises the steps of receiving (1020) one or more modulating signals, generating (1040) one or more modulated sinusoidal carrier waves with zero side bands, including one or more wave cycles at carrier frequency that have a predetermined one or more properties, defined for complete cycle at the beginning of each sine cycle at one or more zero voltage crossing points in accordance with the one or more values of the one or more modulating signals. The one or more predetermined properties to change, is selected from group of amplitude, frequency, phase, time period and combinations thereof.
Patent PT-101961-A (PT)
Title: Support for washing vehicle wheels
IPC: B08B3/02
Filed: 1997-01-29
Abstract: Support that can not only be incorporated into a more complex machine for washing wheels but also be used directly by the operator, specifically in the case of manual washing using a pressurized water jet. Said support is characterized by one or more lanes 1, each one of which has a shaft 2 about which it can rotate on itself in the same plane as that which contains it, by a fixed support 3 and by groups of holes 12 for fastening of a removable support 4 capable of being mounted parallel to the fixed support and at a desired distance from the latter, and also by a manual-actuation or motorized device 5 that promotes rotation of said lane (lanes) 1. Preferably, the device 5 consists of a crank 51 coupled to a shaft 52 that actuates a command pinion that, by means of a chain 6, transmits the rotational movement of the crank to a controlled pinion wheel 21 integral with the first lane 1. In turn, a controlling pinion wheel 22 actuates the controlled pinion wheel of the following lane by means of a chain 7, and so on in succession. <IMAGE>
Patent PT-102661-A (PT)
IPC: A47K3/16
Filed: 2001-08-24
Abstract: This invention relates to an inspection door that provides an easy, fast and frequent access for regular inspection and eventual repair to the discharge valves and/or fittings installed upon de output piping from a bathtub namely a hydromassage bathtub. It is mounted as an integral part of the masonry wall, for example made of brick, used to protect the bathtub, and it comprises: a) right (1) and left (2) doorframes for the settlement of the inspection door upon an opening made in said masonry wall; b) inspection door tiltable in the front to rear direction around an axle between a closed position (Fig. 5) and an opened position (Fig. 6). <IMAGE>   <IMAGE>
Patent PT-104904-A (PT)
Title: Misturas à base de hidrogéis de goma gelana para regeneração de tecido adiposo
Inventor: OLIVEIRA JOAO MANUEL TEIXEIRA DE
IPC: A61L27/00
Filed: 2009-12-21
Abstract: A PRESENTE INVENÇÃO REFERE-SE AO PROCESSAMENTO DE IMPLANTES MOLDÁVEIS PARA APLICAÇÃO SUBCUTÂNEA OBTIDOS ATRAVÉS DA COMBINAÇÃO DE UM HIDROGEL À BASE DE GOMA GELANA E UMA OU MAIS FRACÇÕES DE TECIDO ADIPOSO DE ORIGEM HUMANA OU ANIMAL. A APLICAÇÃO DESTES IMPLANTES DESTINA-SE AO CAMPO DA MEDICINA REGENERATIVA E DA ENGENHARIA DE TECIDOS, NOMEADAMENTE SUBSTITUIÇÃO DE TECIDO ADIPOSO REMOVIDO POR EXEMPLO DURANTE PROCEDIMENTOS CIRÚRGICOS (EX: MASTECTOMIA TOTAL OU PARCIAL). NESTA INVENÇÃO SÃO FOCADOS ASPECTOS RELACIONADOS COM O TIPO DE BIOMATERIAL UTILIZADO, ESPECIFICAMENTE TIPOS DE GOMA GELANA E SEU PROCESSAMENTO, CARACTERÍSTICAS RESPEITANTES ÀS FRACÇÕES DO TECIDO ADIPOSO UTILIZADAS, E MÉTODOS DE FABRICO E APLICAÇÃO DOS IMPLANTES MOLDÁVEIS FABRICADOS. A PRESENTE INVENÇÃO TEM COMO OBJECTIVO O FABRICO DE IMPLANTES MOLDÁVEIS CAPAZES DE SUBSTITUIR TECIDO ADIPOSO EM FALTA DE CORRENTE DE PROCESSOS CIRÚRGICOS, TRAUMATOLÓGICOS, OU DEGENERATIVOS.
Patent PT-105743-A (PT)
Title: Alça traseira híbrida para motos
Inventor: SA RICARDO FIGUEIREDO DE
IPC: B62K19/00
Filed: 2011-06-06
Abstract: O PRESENTE INVENTO DIZ RESPEITO UMA ALÇA TRASEIRA HÍBRIDA PARA MOTOS QUE COMPREENDE UMA ESTRUTURA METÁLICA DE LIGAÇÃO ENTRE A TRASEIRA DA MOTO E A BASE DE FIXAÇÃO DA MALA EAO APOIO DO PASSAGEIRO, FIXO NA TRASEIRA DA MOTO, COMPLETAMENTE RECOBERTA COM UM POLÍMERO, CARACTERIZADA POR COMPREENDER TRÊS ELEMENTOS METÁLICOS: - UM ELEMENTO ANTERIOR (1) FORMADO POR UMA PLACA METÁLICA DE BASE CUJAS EXTREMIDADES SÃO RECURVADAS; - UM ELEMENTO POSTERIOR (2) OU APOIO TRASEIRO COM A CONFIGURAÇÃO DE UM 'U' E CUJAS EXTREMIDADES DAS ABAS SÃO REVIRADAS A 90º; - UM ELEMENTO DE REFORÇO (3) QUE LIGA AS ABAS DO 'U' DO SEGUNDO ELEMENTO; SENDO AS DIFERENTES PARTES UNIDAS PELO POLÍMERO AQUANDO DA SUA INJECÇÃO SOBRE AS PARTES METÁLICAS DEVIDAMENTE MONTADAS DE MODO A FORMAR UMA ESTRUTURA FECHADA.