baber/WOPTO huggingface dataset:
Patent CA-2386374-A1 (CA)
Inventor: AGUILAR-CORDOVA CARLOS ESTUARD
IPC: C12N15/861
Filed: 2000-10-07
Abstract: A method is disclosed for decreasing or retarding an increase in the size of a localized or metastatic tumor by using a combination of gene therapy and other therapies, including radiation therapy, chemotherapy, surgery, immunotherapy, and antihormone therapy.
Patent CA-2386626-A1 (CA)
Title: Targeted vectors
Inventor: MURPHY RICHARD
IPC: C12N15/86
Filed: 2000-10-13
Abstract: This invention provides therapeutic and diagnostic agent delivery vehicles, including viral vectors, that are complexed to a targeting moiety by coordinate covalent linkages mediated by a transition metal ion. The complex  is typically formed with a transition metal ion that is in a kinetically labile oxidation state; after the complex is formed, the oxidation state of the transition metal ion is changed to one that renders the complex kinetically stable. The use of a coordinate covalent linkage to attach the targeting moiety to the delivery vehicle provides advantages such as the ability to readily attach a different targeting moiety to a delivery vehicle  without modifying the delivery vehicle itself. This flexibility is achieved without sacrificing stability of the complex.
Patent CA-2389820-A1 (CA)
Inventor: FEDELI JEAN-MARC
IPC: H01H59/00
Filed: 2002-06-17
Abstract: Composant microélectromécanique (1) assurant des fonctions de filtrage, réalisé sur un substrat à base de matériau semi-conducteur, et comportant deux bornes d'entrée et deux bornes de sortie, caractérisé en ce qu'il comporte également : .cndot. un équipage mobile (4) relié au substrat par au moins une portion déformable, et incluant une région réalisée en un matériau ferromagnétique ; .cndot. un bobinage métallique (5) relié aux bornes d'entrée ou de sortie (30, 31), apte à interagir magnétiquement avec la région en matériau ferromagnétique de l'équipage mobile (4) ; .cndot. une surface formant une première électrode (6), reliée à une des bornes de sortie ou d'entrée, disposée en regard d'une surface complémentaire solidaire de l'équipage mobile (4), cette surface complémentaire formant une seconde électrode reliée à l'autre des bornes de sortie ou d'entrée, et étant apte à interagir électrostatiquement avec la première électrode (6).
Patent CA-2390689-A1 (CA)
Inventor: HILLMAN JENNIFER L
IPC: A61K48/00
Filed: 2000-12-13
Abstract: The invention provides human lyases and associated proteins (HLYAP) and polynucleotides which identify and encode HLYAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HLYAP.
Patent CA-2391466-A1 (CA)
Inventor: CITTERIO MAURO
IPC: A61M15/00
Filed: 2002-06-25
Abstract: An inhaler device comprises an inhaler body defining a recess for a capsule holding herein a substance to the inhaled, and a nosepiece communicating with the capsule, and a perforating element coupled to the inhaler body and provided for perforating the capsule for allowing an outside air flow to be mixed with the capsule contents and inhaled through the nosepiece.
Patent CA-2392630-A1 (CA)
Title: 2-amino-5,6-dihalo-3,4-dihydroquinazolines with blood platelet reducing properties
Inventor: LANG PHILIP CHARLES
IPC: A61K31/517
Filed: 2000-11-29
Abstract: Compounds of formula (E) (wherein X and Y, which may be the same or differen t, each represents Cl, Br or F) and tautomers thereof have been found to have enhanced platelet count reducing properties. Also provided are methods for synthetically making the compounds of formula (E) and pharmaceutically acceptable addition salts thereof and a method of reducing the platelet coun t in patient by administering to the patient a platelet reducing effective amount of a compound of formula (E) preferably together with a pharmaceutically acceptable carrier. A pharmaceutical composition is also provided which contains a compound of formula (E) as the active ingredient together with pharmaceutically acceptable excipients. Further provided is a compound of formula (E) for use in therapy and the use of a compound of formula (E) for preparing a medicament for reducing platelet count in a patient.
Patent CA-2393030-A1 (CA)
Inventor: EMORI YOSHIHIRO
IPC: H01S3/30
Filed: 2002-07-11
Abstract: In a Raman optical amplification system in which WDM optical signals comprising two or more signal bands are transmitted in a transmission line, and in which a plurality of pumping lightwaves are introduced into said transmission line so that WDM optical signals in the shortest signal band are Raman-amplified by said plurality of pumping lightwaves, the interval between the longest pumping wavelength and the next-longest pumping wavelength differs by 0.2 to 1.4 THz in frequency. This makes it possible to flatten the level of the WDM signals by means of canceling the Raman gain ripple on the longer wavelength region of the distributed amplification.
Patent CA-2394126-A1 (CA)
Inventor: SCHULEIN JURGEN
IPC: C12Q1/6825
Filed: 2000-12-13
Abstract: La présente invention concerne un procédé de détection et de quantification d'une première biomolécule (5, 8) qui est contenue dans une solution. Ce procédé consiste : a) à lier la première biomolécule (5, 8) à une seconde biomolécule (3, 7) qui présente au moins partiellement une affinité spécifique par rapport à la première biomolécule et b) à mesurer la conductivité électrique du complexe formé par la première biomolécule (5, 8) et la seconde biomolécule (3, 7), la seconde biomolécule (3, 7) formant un pont entre une première électrode (2a) et une seconde électrode (2b).
Patent CA-2396057-A1 (CA)
Inventor: CHANE-CHING JEAN-YVES
IPC: C09K23/00
Filed: 2000-12-29
Abstract: L'invention concerne une dispersion colloïdale aqueuse de type nanométrique colloïdale aqueuse au sein de laquelle le diamètre moyen des particules colloïdales est au plus de 6nm, ladite dispersion comprenant: (1) au moins u n composé d'un métal M, ledit métal M étant un métal majoritaire au sein de la  dispersion, choisi dans le groupe constitué de l'aluminium, du zirconium et des métaux de la classification périodique dont le numéro atomique est compr is entre 22 et 31; et (2) au moins un complexant présentant un pKs(M)(cologarithme de la constante de dissociation du complexe formé par le  complexant et le cation dudit métal M) supérieur à 2. L'invention concerne également le procédé de préparation de cette dispersion. La dispersion ainsi  obtenue peut notamment être utilisée dans la préparation de filtres anti-UV,  en catalyse, ou encore comme renfort de matrices polymères ou minérales.</SD OAB>
Patent CA-2399987-A1 (CA)
Title: Linear recliner with plastic housing
Inventor: FISHER ALFRED J JR
IPC: B60N2/22
Filed: 2001-02-02
Abstract: A seat recliner apparatus (10) according to the invention controllably adjusts the angular position of a seat back (16) relative to a seat base structure (18) and is responsive to remote actuation by an operator. The apparatus includes a driven mechanism (26) having a recliner rod (48) adapted to be connected to the seat back (16), a drive mechanism (24) having a motor (30) for rotating the transmission rod (32) in a first and second direction, and a housing adapted to be connected to the seat base structure. The housing (94) receives the recliner rod (48) and the transmission rod (32) for operative interconnection, whereby rotation of the transmission rod (32) in the first or second direction causes the recliner rod (48) to move relative to the housing in a corresponding first and second linear direction. The housing (94) is formed of a polymeric material.
Patent CA-2403132-A1 (CA)
Title: Method and apparatus for manufacturing a fuel cell electrode
Inventor: MURATE MASASHI
IPC: H01M8/10
Filed: 2002-09-11
Abstract: In the method and apparatus for manufacturing a fuel cell electrode, electrode material is electrostatically held on a photosensitive drum with a prescribed pattern. The electrode material of the prescribed pattern is then transferred from the photosensitive drum onto an electrolyte membrane or a membrane of a diffusion layer. The transferred electrode material of the prescribed pattern is then fixed to the membrane. The electrode material may be electrostatically applied to the membrane a plurality of times in order to vary the electrode structure in the thickness direction.
Patent CA-2404390-A1 (CA)
Title: Methods of therapy for non-hodgkin's lymphoma using a combination of an antibody to cd20 and interleukin-2
Inventor: WOLIN MAURICE J
IPC: A61P35/00
Filed: 2001-03-23
Abstract: Methods for treating a mammal with lymphoma using a combination of interleuk in- 2(IL-2) or variant thereof and at least one anti-CD20 antibody or fragment thereof are provided. These anti-tumor agents are administered as two separa te pharmaceutical compositions, one containing IL-2 (or variant thereof), the other containing at least one anti-CD20 antibody (or fragment thereof), according to a dosing regimen. Administering of these two agents together potentiates the effectiveness of either agent alone, resulting in a positive  therapeutic response that is improved with respect to that observed with either agent alone. The anti-tumor effects of these agents can be achieved using lower dosages of IL-2, thereby lessening the toxicity of prolonged IL- 2 administration and the potential for tumor escape.
Patent CA-2404815-A1 (CA)
Inventor: WINTHER HENRIK
IPC: A01C7/08
Filed: 2001-04-11
Abstract: An arrangement for spreading material, comprising at least one container (1)  for holding the material (6) and having a conveyor duct (2), which is connected to the container (1) and is designed to accommodate an air flow fo r conveying the material (6) from the container (1) to at least one dispensing  element (12). The conveyor duct (2) is provided with a venturi-like constriction (18) and the container (1) is connected to the conveyor duct (2 ) by the said constriction (18), so that the material (6) is fed from the container (1) to the conveyor duct (2) by means of the venturi effect.</SDOA B>
Patent CA-2406204-A1 (CA)
Title: Method of reducing particulates and enhancing burning rate within a combustion chamber
Inventor: LI GUOWEI
IPC: F02B3/06
Filed: 2002-10-02
Abstract: Disclosed is a method and apparatus to generate turbulence and impact on soot rich zone within a burning fuel jet within a combustion chamber of an internal combustion engine. A reservoir is disclosed for accumulating charge and projecting that charge into a combustion chamber and into and around the burning fuel directly injected into the combustion chamber. A ring or the fire deck define one or many reservoirs with a orifice for accumulating, directing and ejecting the charge is disclosed. Gaseous fuels can benefit from the disclosure.
Patent CA-2406232-A1 (CA)
Title: Plants containing a cytosolic acetyl coa-carboxylase nucleic acid
Inventor: DEBONTE LORIN R
IPC: A01H5/00
Filed: 2001-04-20
Abstract: Plants are disclosed that contain a recombinant nucleic acid construct comprising a nucleic acid encoding a cytosolic acetyl coA-carboxylase (ACCase) operably linked to a promoter. Seeds produced from such plants exhibit statistically significantly increased oil content as compared to seeds produced by a corresponding plant lacking the nucleic acid encoding the ACCase. Methods of producing seeds exhibiting statistically significantly increased oil content are also disclosed.
Patent CA-2406671-A1 (CA)
Inventor: LI WEN-QING
IPC: A63C17/06
Filed: 2002-10-04
Abstract: A replaceable skate assembly includes a boot, a base mounted on a bottom of the boot, and a locking device mounted in the base. The locking device includes a positioning rod, a locking pawl, and a spring. Thus, the base may be assembled on and detached from the bottom of the boot quickly, easily and conveniently, thereby facilitating the user using the replaceable skate assembly In addition, the bottom of the boot is integrally formed with the boot, without having to additionally provide an aluminum alloy structure on the bottom of the boot, thereby simplifying the procedure of fabrication, and thereby decreasing the cost of fabrication.
Patent CA-2408285-A1 (CA)
Title: Cooling method for controlled high speed chilling or freezing
Inventor: WOOD BRIAN
IPC: F25D31/00
Filed: 2001-05-16
Abstract: A cooling method for controlled high speed chilling or freezing is disclosed . Cooling fluid is circulated by a submersed circulator, such as a motor, at a  substantially constant velocity past a substance to be cooled. The velocity of fluid flow is maintained despite changes in the viscosity of the cooling fluid, by either increasing or decreasing the amount of torque supplied by t he motor. The cooling fluid is cooled to a desired temperature by circulating t he fluid past a multi-path heat exchanging coil connected to a refrigeration system. An optimal cooing fluid temperature for a variety of applications is  in the range of about -24 ~C to -26 ~C, resulting in significant efficiency gains over conventional cooling processes.
Patent CA-2411410-A1 (CA)
Title: System and method for providing protection of data communications in packet-based networks
Inventor: MARK BARRY DING KEN
IPC: H04L12/18
Filed: 2002-11-08
Abstract: A method and system for providing protection of data communications in packet-based networks is provided, using a combination of unicast to multicast conversion and providing formation of virtual output queues (VOQs) which are separate for each pair of the target port and protection ports on the target network device. As a result, the system requires less bandwidth resources and reduces or eliminates network performance problems associated with other existing solutions.
Patent CA-2413487-A1 (CA)
Inventor: MUNSON GARY A
IPC: H04Q3/00
Filed: 2002-12-03
Abstract: An enhanced intelligent network telephony system includes at least one service nodes (SN) imbued with special routing, message handling and billing capabilities. Using the Extension Parameter in an Analyze-Route message, a service control point (SCP) provides a set of service node parameters including service node identification and message content. The SN receives, processes and implements the services corresponding to the message content. Included among these may be announcement IDs corresponding to announcements, such as advertisements, that the SN can initiate at an intelligent peripheral for playing to calling and called parties, and routing numbers which the SN can use to route a particular destination under certain conditions as per the service needs. The SN is also able to request an originating switch to update an Automated Message Accounting (AMA) record created at the originating switch, using information created by the SN.
Patent CA-2414284-A1 (CA)
Title: Method and system for visual network searching
Inventor: EYAL AVIV
IPC: G06F17/30
Filed: 2002-04-25
Abstract: An embodiment provides for conducting searches on a network (Fig. 1). A search request (Fig. 1) is signaled over the network (Fig. 1) to a search engine (130). A search result (Fig. 1) is received that identifies a plurality of network addresses. Multiple pages are automatically rendered, each page being located by a corresponding network addresses in the search result (Fig. 1).
Patent CA-2422778-A1 (CA)
Title: Implant set and corresponding implants
Inventor: PELTIER GUY GABRIEL
IPC: B22C9/20
Filed: 2001-09-18
Abstract: In an arrangement for anchoring a threaded implant (1) in dentine (2) by means of a screwing instrument (6), use is made of an implant which, at its upper part, is provided with an anchoring hole (1c) for a screw (5) intended to secure an element or fixture holder (4) that can be attached to the implant. The centre axis of the anchoring hole is inclined in relation to the longitudinal axis (1b) of the implant. The element is provided with means (4d) for cooperation with the instrument (6). The element and its means of cooperation permit application of the instrument in a way which ensures that the axis of rotation (6d) of the instrument essentially coincides with a continuation of the longitudinaxis (1b) of the implant.
Patent CA-2423356-A1 (CA)
Title: Zwitterionic tachykinin receptor antagonists
Inventor: MEURER LAURA C
IPC: C07D401/04
Filed: 2001-09-21
Abstract: The present invention is directed to certain novel compounds represented by structural formula (I), or a pharmaceutically acceptable salt thereof, wherein R3, R5, R6, R7, R8, R11, R12, R13, Q, W, X, Y and Z are defined herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are tachykinin receptor antagonists and are useful in the treatment of psychiatric disorders including depression and anxiety.
Patent CA-2424772-A1 (CA)
Title: Method of performing a lasik procedure and tonometer system for use therewith
Inventor: BRUCE JOHN C
IPC: A61F9/013
Filed: 2001-10-19
Abstract: A method of performing a LASIK procedure. The method includes providing LASI K instrumentation, preferably including an automated microkeratome instrument and an excimer laser. The microkeratome device includes both a microkeratome  as well as a suction ring. A high-pressure range tonometer instrument is als o provided. The tonometer includes a probe for sensing a parameter of the eye indicative of intraocular pressure, and is capable of providing intraocular pressure measurements in excess of 80mm Hg; more preferably in excess of 100  mm Hg; most preferably up to or in excess of 120 mm Hg.
Patent CA-2425562-A1 (CA)
Title: Nasal epidermal lifting mechanism
Inventor: BEAUDRY WALLACE J
IPC: A61F13/00
Filed: 1997-01-17
Abstract: An epidermal lifting mechanism comprising at least one strip of flexible material, first and second end portions, a middle portion, adhesive material, a plurality of resilient spring structures extending through the at least one strip of flexible material, and a flap mechanism integral with the middle portion.
Patent CA-2425952-A1 (CA)
Title: Distribution layer having improved liquid transfer to a storage layer
Inventor: GRAEF PETER A
IPC: A61F13/511
Filed: 2001-12-07
Abstract: A fibrous layer that includes a refined blend of crosslinked cellulosic fibe rs and noncrosslinked cellulosic fibers. In one embodiment, the layer includes about 85 percent by weight crosslinked fibers and about 15 percent by weight  noncrosslinked fibers. An absorbent construct that includes the fibrous laye r and a liquid storage layer. Personal care absorbent products that include th e distribution layer.
Patent CA-2426534-A1 (CA)
Title: Use of disazo compounds
Inventor: LEHR FRIEDRICH
IPC: C09D11/02
Filed: 2001-12-03
Abstract: The invention relates to the use of disazo compounds according to formula (I ) wherein all substituents are as defined in claim 1salts thereof and mixtures  of these compounds for dyeing or printing organic sub-strates, to novel compounds, to the process for the production of these compounds and to substrates dyed or printed by these compounds.
Patent CA-2426691-A1 (CA)
Inventor: SAND PAUL M
IPC: B01F27/906
Filed: 2001-10-25
Abstract: L'invention se rapporte à un dispositif permettant de mélanger et de transférer une matière de remplissage des os. Ce dispositif comporte un récipient conçu pour contenir des composants dans un état non mélangé. Un élément de mélange qu'il est possible d'introduire dans ledit récipient permet de mélanger les composants et un actionneur comportant un élément d'entraînement et un élément entraîné est couplé de manière amovible à l'élément de mélange.
Patent CA-2432490-A1 (CA)
Title: Improved film cooling for microcircuits
Inventor: BLAIR MICHAEL F
IPC: B81B7/04
Filed: 2003-06-16
Abstract: An embedded microcircuit for producing an improved cooling film over a surface of a part, comprising an inlet through which a coolant gas may enter, a circuit channel extending from the inlet through which the coolant gas may flow, and a slot film hole formed at a terminus of the circuit channel through which the coolant gas may exit a part.
Patent CA-2434731-A1 (CA)
Inventor: FLAHERTY J CHRISTOPHER
IPC: A61P25/28
Filed: 2002-02-22
Abstract: L'invention concerne un dispositif permettant d'administrer un fluide. Ce dispositif comprend un ensemble jetable qui comporte un ensemble de sortie et un élément doseur du distributeur, permettant de réguler le débit du fluide vers l'ensemble de sortie, et un ensemble réutilisable comprenant un élément de commande du distributeur, qui permet de commander l'élément de dosage du dispositif distributeur lorsque l'ensemble réutilisable et l'ensemble jetable sont assemblés, un processeur local connecté avec le distributeur et programmé de manière à produire un écoulement de fluide à travers le distributeur en direction de l'ensemble de sortie, conformément aux instructions de débit, et un élément de communication local sans fil, connecté avec le processeur local, qui reçoit des instructions relatives au débit à partir d'un dispositif sans fil éloigné. Ces ensembles sont conçus pour pouvoir être montés de manière amovible et l'ensemble jetable contient une source d'alimentation qui permet de fournir de l'énergie à l'ensemble réutilisable après que l'ensemble réutilisable et l'ensemble jetable ont été assemblés.
Patent CA-2435475-A1 (CA)
Inventor: ROCKSTAD JORDAN GABRIEL
IPC: F24B1/20
Filed: 2003-07-17
Abstract: A convertible grill and fireplace having a single firebox and lid, both of which may be used in both a grill configuration and a fireplace configuration. A detachable and foldable screen assembly is used in the fireplace configuration. The screen assembly fits between the firebox and the lid, and includes a series of panels that may be folded together to form a compact unit. Successive panels of the screen assembly are shorter in length so that they may be folded into one another. This feature permits the screens to be folded into a compact configuration, even if the screen assembly and the convertible grill and fireplace have a circular cross-section. The convertible grill and fireplace also includes retractable legs so that the firebox may be lowered or raised as desired.
Patent CA-2437012-A1 (CA)
Inventor: RAPAILLE G CLOTAIRE
IPC: G06Q30/00
Filed: 2003-08-12
Abstract: An advertisement for leather clothing comprising at least one image, and including reference to a first state, reference to a second state, and indicating that transformation from said first state to said second state may be facilitated by wearing at least one leather garment.
Patent CA-2438003-A1 (CA)
Title: Drilling fluid additive system containing talc & carrier
Inventor: RAYBORN JERRY
IPC: C09K8/22
Filed: 2003-08-21
Abstract: A drilling fluid additive system is provided wherein the system is manufactured by a method comprised of admixing colloidal solids such as talc with a carrier such as oils, glycols, esters, cellulose or olefins to create a suspended mixture to thereby allow the colloidal solids to be pre-wet or coated with the carrier; and then admixing copolymer beads to the suspended mixture to allow the beads to be pre-wet or coated with the carrier; and then adding the suspended mixture with a mixture comprised of hydrophilic clay, a pH controller, a fluid loss controller, and a dispersant.
Patent CA-2439197-A1 (CA)
Title: Domaine de liaison du ligand du recepteur hormonal nucleaire
Inventor: PHELPS CHRISTOPHER BENJAMIN
IPC: C07K16/28
Filed: 2002-03-05
Abstract: Cette invention concerne de nouvelles protéines, appelées BAA91543.1, identifiées dans l'invention comme étant un Domaine de Liaison du Ligand du Récepteur Hormonal Nucléaire, ainsi que l'utilisation de cette protéine et de la séquence d'acide nucléique provenant du gène codant à des fins diagnostiques, thérapeutiques et de prévention.
Patent CA-2442483-A1 (CA)
Inventor: WHITLOCK GAVIN ALISTAIR
IPC: A61P43/00
Filed: 2002-03-18
Abstract: Compounds of formula (I): (I), and their salts, solvates, prodrugs, etc., wherein the substituents have the values mentioned herein, are Procollagen C-Proteinase (PCP) inhibitors and have utility in conditions mediated by PCP.