Patent SG-11201805142R-A (SG)
Title: Pharmaceutical compositions comprising phenylaminopyrimidine derivative
Inventor: PARVATANENI DURGA MAHESWARI
IPC: A61K9/14
Filed: 2016-01-30
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization 11M1111101110101011111 HO 11111011101011111 001111011111011111110111011# International Bureau 0.. .... .. (10) International Publication Number (43) International Publication Date ..... .....!;,' WO 2017/103941 Al 22 June 2017(22.06.2017) WIPO I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 9/14 (2006.01) A61K 9/08 (2006.01) kind AO, of national protection available): AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (21) International Application Number: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, PCT/IN2016/050035 DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (22) International Filing Date: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, 30 January 2016 (30.01.2016) KZ, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, (25) Filing Language: English PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, (26) Publication Language: English SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: 6951/CHE/2015 18 December 2015 (18.12.2015) IN (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (71) Applicant: NATCO PHARMA LTD [IN/IN]; Natco GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, House, Road No.2, Banjara Hills, Hyderabad 500034 (IN). TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, (72) Inventors: PARVATANENI, Durga Maheswari; Natco TJ, TM), House, Road No.2, Banjara Hills, Hyderabad 500034 (IN). DK, European (AL, AT, BE, BG, CH, CY, CZ, DE, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, MOHANTY, Mitrabhanu; Natco House, Road No.2, LV, SM, Banjara Hills, Hyderabad 500034 (IN). APPAD- GW, KM, ML, MR, NE, SN, TD, TG). WEDULA, Venkata Satyanarayana; Natco House, Road MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, — No.2, Banjara Hills, Hyderabad 500034 (IN). AD- Declarations under Rule 4.17: IBHATLA, Kali Satya Bhujanga Rao; Natco House, of inventorship (Rule 4.17(iv)) Road No.2, Banjara Hills, Hyderabad 500034 (IN). NAN- NAPANENI, Venkaiah Chowdary; Natco House, Road Published: No.2, Banjara Hills, Hyderabad 500034 (IN). — with international search report (Art. 21(3)) = = = = = = = = = = = Il Il 7r C:r M © Il IN 1-1 (54) Title: PHARMACEUTICAL COMPOSITIONS COMPRISING PHENYLAMINOPYRIMIDINE DERIVATIVE 0 N (57) : An oral pharmaceutical formulation containing an effective amount of NRC-AN-019 including its pharmaceutically en. ) acceptable salts and polymorphs thereof, by dispersing in a polymer system in a fmal state of subdivision to enhance oral bioavailab - ,71 . 9 ility. It also relates to processes for the preparation of such compositions and using those compositions for the treatment of Chronic Myeloid Leukemia and other tumors such as head and neck cancer, prostate cancer and the like.