baber/WOPTO huggingface dataset:
Patent NZ-579734-A (NZ)
Title: Platelet derived growth factor receptor-beta antibodies
Inventor: ZHU ZHENPING
IPC: A61P35/00
Filed: 2008-04-17
Abstract: Disclosed is an antibody or functional fragment thereof that binds human platelet derived growth factor receptor-beta antibodies (PDGFRbeta), comprising a CDRH1 having the sequence SYAIS (SEQ ID NO:20), a CDRH2 having the sequence RIIPILGIANYAQKFQG (SEQ ID NO:22), a CDRH3 having the sequence DMGSRNYYYFY (SEQ ID NO:24), a CDRL1 having the sequence RASQSVGRYLA (SEQ ID NO:28), a CDRL2 having the sequence GASNRAT (SEQ ID NO:30), and a CDRL3 having the sequence QQRSNWPLT (SEQ ID NO:32). The antibody is suitable for the treatment of cancer including ovarian, non-small-cell lung cancer (NSCLC), pancreatic, colon, and giloblastoma.
Patent NZ-581548-A (NZ)
Title: Container for storing and unloading bulk material, the container having an internal hopper
Inventor: KERNKAMP MICHIEL
IPC: G07F11/44
Filed: 2008-06-23
Abstract: The present invention relates to container (1) for storing and unloading bulk material comprising a vessel (2) presenting a closed end (3) and an openable end (4), a hopper (5) placed inside the vessel (2) and tapering to a discharge outlet in a direction of the vessel openable end (4) and a tearable membrane (7) closing the hopper (5) and the vessel (2) at the openable end.
Patent NZ-581595-A (NZ)
Title: Means for reducing acetoin buildup in alcoholic fermentation media
Inventor: DEQUIN SYLVIE
IPC: C12G1/02
Filed: 2008-05-06
Abstract: A method to reduce the amount of acetoin that accumulates in yeast. The method comprises producing a yeast strain in which the BDH1 gene encoding Bdh1p is overexpressed. The overexpression catalyses the reduction of acetoin to 2,3-butanediol according to a rate that is at least twice that of the initial strain. The yeast can be used in methods for fermenting fruit juice, in particular grape juice, and for producing 2,3-butandiol.
Patent NZ-582263-A (NZ)
Title: A waterproof and breathable shoe
Inventor: POLEGATO MORETTI MARIO
IPC: A43B7/08
Filed: 2004-12-27
Abstract: A breathable, waterproof shoe comprises an assembly 501 of a breathable upper 511, a waterproof membrane 521 and a sole 500, which surrounds the foot in a pouch like manner with at least the lower section of the upper 512 associated with the waterproof membrane 521. The sole 500 has two layers with the lower layer 514 having portions open to the upper layer and forming a support structure with the tread, and the upper layer 515 being microporous and permeable to water vapour. The upper 511 is coupled externally to the sole 500 by its lower edges 512a, and the upper 511 is coupled internally to the waterproof membrane 521. This arrangement does not compromise the shoe's waterproofness.
Patent NZ-583992-A (NZ)
Title: A gene expression system for controllable expression of ethylene response in a plant
Inventor: ROSICHAN JEFFREY L
IPC: C12N5/04
Filed: 2008-09-09
Abstract: Disclosed is a method for producing a transgenic plant comprising: (a) transforming at least one cell in the plant with a gene expression system comprising: i. an activation cassette comprising, under control of a suitable promoter and in operative association therewith, (a) a GAL 4 DNA-binding domain (DBD) that recognizes a selected response element comprising five copies of GAL4; (b) an ecdysone receptor ligand binding domain (EcRLBD); and (c) a VP 16 activation domain (AD) which is activated in the presence of an inducing composition; and a target cassette comprising (d) an inducible promoter comprising, in operative association, the response element to which the DBD of (a) binds and a minimal promoter responsive to the AD of (c), the inducible promoter controlling expression of (e) a nucleic acid sequence that encodes a selected protein that modifies sensitivity to ethylene in the plant, said protein selected from the group consisting of ethylene biosynthesis genes ACS and ACO, ACC deaminase, ethylene receptor genes, ETR1, ETR2, ERS1, ERS2 and EIN4, ethylene signaling pathway genes, RTE1, CTR1, EIN2, EIN3 and EIN3-like (EIL1-5), ethylene response factors, ERF1, EDF1, EDF2, EDF3 and EDF4, and EIN3 binding F-box proteins, EBF1 and EBF2, and mutants thereof; wherein interaction among the components of the activation cassette and the target cassette, when in a plant cell, with an inducing composition, modulates expression of the selected protein and selectively modulates ethylene sensitivity in the plant cell; (b) generating a plant from the transformed plant cell; and (c) selecting a plant comprising a transformed plant cell, which plant demonstrates selective modulation of ethylene insensitivity when the plant is contacted with the inducing composition, the modulation in protein expression controlled by the timing, the concentration, and the duration of the application of the inducing composition.
Patent NZ-584480-A (NZ)
Title: Novel aryl potassium channel blockers and uses thereof
Inventor: FLYNN BERNARD LUKE
IPC: C07D295/088
Filed: 2008-10-03
Abstract: A compound according to formula (I) where R1, R2, R4, R5, R6, R7, L, L', Y and Y' are defined as in claim 1. The compound can be used to modulate the activity of the potassium channel activity, in particular the activity of the Kv1.3 channels found in T cells. The compound can be used for the treatment or prevention of autoimmune and inflammatory diseases, including multiple sclerosis (MS) and diabetes.
Patent NZ-589520-A (NZ)
Title: Setting power control for a first message based on power used for successfully transmitted preamble
Inventor: CHEN WANSHI
IPC: H04W52/16
Filed: 2009-06-23
Abstract: A method and an apparatus for transmit power control of a first message on physical uplink shared channel during a random access channel procedure on physical random access channel are disclosed. The apparatus comprises a means for performing transmit power control on transmitting a random access channel preamble sufficient for successful receipt; a means for receiving a random access response including a transmit power control command for physical uplink shared channel; and a means for setting transmit power control for a first message transmitted on physical uplink shared channel based at least in part upon the transmit power control command. The means of the apparatus comprise a transmitter for transmitting a physical random access channel and physical uplink shared channel; a receiver; a medium access control layer for performing transmit power control on transmitting the random access channel preamble; and a physical layer for setting transmit power control for the first message transmitted on physical uplink shared channel based upon the random access channel preamble that was successfully received. A method and an apparatus for transmit power control of a first message on physical uplink shared channel during a random access channel procedure on physical random access channel are disclosed. The apparatus comprises means for receiving a random access channel preamble; means for acknowledging successful receipt of the random access channel preamble; means for receiving a random access channel message containing an indication of transmit power control used for the random access channel preamble that was successfully received; and means for transmitting a random access response including a transmit power control command for a first message transmitted on physical uplink shared channel based at least in part upon a transmit power control for the random access channel preamble that was successfully received. The means of the apparatus comprise a receiver for receiving the random access channel preamble on the physical random access channel; a transmitter for acknowledging successful receipt of the random access channel preamble; the receiver further for receiving the random access channel message containing the indication of transmit power control for the random access channel preamble that was successfully received; and a computing platform for transmitting via the transmitter the random access response including the transmit power control command for the first message transmitted on physical uplink shared channel based at least in part upon the transmit power control for the random access channel preamble that was successfully received.
Patent NZ-591596-A (NZ)
Title: Method of concentrating shear-sensitive biopolymers using hollow fibre membranes
Inventor: MITTERER ARTUR
IPC: A61M1/16
Filed: 2009-08-27
Abstract: Disclosed is a method for concentrating shear sensitive biopolymers such as von Willebrand factor, the method comprising flowing a mixture comprising a shear sensitive biopolymer into a hollow fiber (hollow fibre) dialysis module to form a retentate having a shear sensitive biopolymer concentration that is greater than that of the mixture.
Patent NZ-591655-A (NZ)
Title: Container holder with arrangement of fasteners for ease of attachment and detachment
Inventor: MESSNER WILLIAM
IPC: A45F3/14
Filed: 2009-08-10
Abstract: CONTAINER HOLDER WITH FASTENERS Disclosed is a holder for a container of predetermined circumference and length that retains the container within. The holder has a plurality of attachment points that communicate with a plurality of fasteners each at predetermined locations whereby the container is retained within the holder is a stationary horizontal position relative to the user. The holder can directly attach and/or detach from any host device, belt or harness system.
Patent NZ-595062-A (NZ)
Title: Process for making a milk-based protein hydrolysate
Inventor: OESTERGAARD PETER R
IPC: A23L1/305
Filed: 2010-03-31
Abstract: Disclosed is a process for the preparation of a milk-based protein hydrolysate comprising treatment of a solution of a milk-based proteinaceous material with (a) a trypsin-like endopeptidase produced from a microorganism, and (b) at least one other endopeptidase produced from a microorganism.
Patent NZ-595092-A (NZ)
Title: Application apparatus and method
Inventor: YAMAMOTO HIROKI
IPC: B05C1/12
Filed: 2010-03-02
Abstract: 595092 An application apparatus (100) suitable for applying an application material, such as an adhesive agent or pigment or other liquefied fluidic material, to a continuous web (200) being conveyed is disclosed. The apparatus comprises a handover roll (102), an application roll (103) and two press rolls (104, 105). The handover roll receives the application material from a storage unit (101). The application roll receives the application material from the handover roll and applies the received application material to the web. The two press rolls are located on the same side of the web, horizontally either side of the application roll, and press the web against the application roll. A further feed roll (106) is provided downstream of the press rolls which rotates faster than a conveyance speed of the web to stretch the web in the direction of conveyance, and thus convey the web under tension.
Patent NZ-599748-A (NZ)
Title: Improving memory in subjects with mini-mental state examination of 24-26
Inventor: BONGERS ANKE
IPC: A23L33/15
Filed: 2008-06-20
Abstract: 599748 Discloses the use of Uridine or uridine phosphate and Docosahexaenoic acid (DHA) and/or eicosapentaenoic acid (EPA) In the manufacture of a product for improving impaired delayed recall function, for the treatment and/or prevention of an impaired delayed recall function, or improving memory and/or treatment or prevention of impaired memory function in a subject with a mini-mental state examination of 24, 25 or 26, wherein said product is enterally administered to the subject.
Patent NZ-600071-A (NZ)
Title: Electrical Heater with Particular Application to Humidification and Fluid Warming
Inventor: ROW NATHAN JOHN
IPC: A61M16/16
Filed: 2008-06-03
Abstract: A humidifier (51) including:atub(50)configuredtocontainasupplyofwater;
Patent NZ-606079-A (NZ)
Title: An electronic system for marketing foodstuffs
Inventor: PETER ALLNUTT
IPC: G06Q30/06
Filed: 2013-01-22
Abstract: Disclosed is an electronic system (10) for marketing foodstuffs. The system (10) includes an information storage device (14) for electronically storing product information about foodstuffs for sale by foodstuff suppliers. The system further includes a module (16) for a prospective buyer to view the foodstuff product information stored in the information storage device (14) over a data network and a module (17) for registering a prospective buyer request for access to a source of a foodstuff recorded in the information storage device (14). The registering module (17) also sends the source request to the foodstuff supplier over the data network. The electronic system (10) also includes a bargaining module (18) enabling the prospective buyer and a foodstuff supplier to bargain, through communications sent through the data network, a purchase price for a quantity of the foodstuff following buyer sampling. A contracting module (19) is also provided for enabling the foodstuff supplier to contract with the buyer for purchase of a quantity of sampled foodstuff at an agreed purchase price, the bargaining and contracting steps being conducted over the data network.
Patent NZ-609959-A (NZ)
Title: Modified factor ix polypeptides and uses thereof
Inventor: MADISON EDWIN L
IPC: C12N9/64
Filed: 2011-11-03
Abstract: Discloses a modified FIX polypeptide comprising the modifications of R338E and T343R in a mature FIX polypeptide having the sequence of SEQ ID NO: 3, wherein the peptide is 95% identical to SEQ ID NOs: 2, 3, 20 and 394, the polypeptide does not contain modifications in F342I/T343R/Y345T and has increased procoagulant activity.
Patent NZ-618624-A (NZ)
Title: Wetting apparatus and method of use
Inventor: QUIN BERTRAM FRANCIS CHARLES
IPC: B65G31/00
Filed: 2012-12-05
Abstract: Disclosed are a vehicle (1) and method for spreading a particulate material (2) over a ground surface and a wetting apparatus (7) for wetting a particulate material (2). The disclosure notes that current vehicles and methods for spreading particulate material such as fertiliser are subject to inefficient spreading and lack in foliar uptake. The vehicle (1) comprises at least one store (3) of particulate material (2); spreading means (4); conveying means (6) and wetting apparatus (7). The spreading means (4) in the form of one or more spinning discs, a blower or an oscillating spout to spread the particulate material (2) over the ground surface. The conveying means (6) conveys the particulate material (2) from the at least one store (3) to the spreading means (4). The wetting apparatus (7) wets the particulate material (2) or during the act of spreading of the particulate material (2) over the ground surface by the spreading means (4).
Patent NZ-619776-A (NZ)
Title: Heteroaryl compounds as 5-ht4 receptor ligands
Inventor: NIROGI RAMAKRISHNA
IPC: C07D413/14
Filed: 2012-01-05
Abstract: Provided are substituted oxadiazole derivative compounds, of the general formula (I), wherein the variables are as defined in the specification. Examples of the compounds include 6-Chloro-8-{ 5-[1-(2-methoxy-ethyl)-piperidin-4-yl]-[1,3,4]oxadiazol-2-yl} -chroman-5-ylamine and 1-Isopropyl-3-[5-(2-piperidin-1-yl-ethyl)-[1,3,4]oxadiazol-2-yl]-1H-indazole oxalate salt. The compounds are 5-HT4 receptor ligands. The compounds may be useful in the treatment of neurological disorders such as attention deficit hyperactivity disorder, Alzheimer’s disease, cognitive disorders, dementia and schizophrenia.
Patent NZ-706073-A (NZ)
Title: Filtration
Inventor: MEDOFF MARSHALL
IPC: C12P19/02
Filed: 2014-03-07
Abstract: Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example, systems are described that can be useful for separating solids from liquids of saccharified biomass material slurries. Many potential lignocellulosic feedstocks are available today, including agricultural residues, woody biomass, municipal waste, oil seeds/cakes and seaweed, to name a few. At present, these materials are often under-utilized. Disclosed herein includes a method of separating solids from liquids of a slurry, the method comprising: saccharifying the biomass to form a saccharified biomass comprising glucose and xylose, selectively fermenting the glucose in the saccharified biomass to produce a fermentation sugar composition, applying the fermentation sugar composition to a surface of a vacuum belt filter, filtering filtrate through the belt by the action of vacuum applied under the belt and forming a filter cake on top of the belt, extracting sugars from the filter cake by applying an aqueous solution to the filter cake to wash out remaining soluble components in the filter cake, and re-using the aqueous solution for additional washing of filter cake until a concentration of sugars in the aqueous solution is at least 1 wt%.
Patent NZ-709249-A (NZ)
Title: Dispersing feedstocks and processing materials
Inventor: MEDOFF MARSHALL
IPC: C12P7/14
Filed: 2010-11-18
Abstract: A feedstock saccharification system comprising a tank configured to contain a cellulosic or lignocellulosic biomass feedstock having a bulk density of less than 0.75 g/cm3 and a liquid medium, and a dispersing system configured to disperse the biomass feedstock in the liquid medium. There is also a jet mixer configured to mix the contents of the tank, the jet mixer comprising an impeller disposed within a shroud
Patent NZ-712292-A (NZ)
Title: Pyrazole-amide compound and medicinal uses therefor
Inventor: MOTOMURA TAKAHISA
IPC: C07D231/12
Filed: 2014-03-14
Abstract: The present invention discloses a pyrazole-amide compound or a pharmaceutically acceptable salt thereof having a pyruvate dehydrogenase kinase (PDHK) inhibitory activity, a pharmaceutical composition containing the same, a prophylactic or therapeutic agent containing the same for diabetes (type 1 diabetes, type 2 diabetes etc.), insulin resistance syndrome, metabolic syndrome, hyperglycemia, hyperlactacidemia, diabetic complications (diabetic neuropathy, diabetic retinopathy, diabetic nephropathy, cataract etc.), cardiac failure (acute cardiac failure, chronic cardiac failure), cardiomyopathy, myocardial ischemia, myocardial infarction, angina pectoris, dyslipidemia, atherosclerosis, peripheral arterial disease, intermittent claudication, chronic obstructive pulmonary disease, brain ischemia, cerebral apoplexy, mitochondrial disease, mitochondrial encephalomyopathy, cancer, pulmonary hypertension, or Alzheimer disease, and the like.
Patent NZ-725205-A (NZ)
Title: Gemcitabine prodrugs
Inventor: GRIFFITH HUGH
IPC: C07H19/10
Filed: 2015-06-25
Abstract: Prodrug This invention relates to a prodrug of the monophosphate nucleotide of the well-known oncology drug gemcitabine. Specifically, it relates to gemcitabine-[phenyl-benzoxy-L- alaninyl)]-phosphate when present as a single phosphate diastereoisomer and, in particular, it relates to the (S)-phosphate diastereoisomerwhich offers a remarkable and unexpected increase in solubility relative to the (R)-diastereoisomer. The (S)-phosphate epimer is also preferentially taken up into cyclodextrin solutions over the (R)- diastereoisomer.
Patent NZ-726904-A (NZ)
Title: Parking apparatus
Inventor: FORSLUND MICHAEL
IPC: B63H25/48
Filed: 2015-06-03
Abstract: Control apparatus (900) to interact with a jet of water that applies a thrust to propel a marine vessel, comprising a control device (920, 940) shaped to controllably redirect at least a portion of the jet, and a parking apparatus. The parking apparatus comprises a linkage having a range of motion comprising a working range (932, 952) and an extended position (934, 954) beyond the working range. The parking apparatus further comprised an actuator (710, 810) coupled to the linkage, the actuator comprising a a working length (350) to position the linkage within the working range; and an additional distance (370) to position the linkage in the extended position. The invention provides for reducing damage or deterioration within the working range of components associated with steering or propulsion control apparatus for marine vessels, which may be exposed to degrading saline environments. This is achieved by limiting the damage or deterioration to an extended parking position of the components.
Patent NZ-727659-A (NZ)
Title: Residence structures and related methods
Inventor: LANGER ROBERT
IPC: A61K9/00
Filed: 2015-06-11
Abstract: In some embodiments, the structures and systems described herein comprise one or more materials configured for high levels of active substances (e.g., a therapeutic agent) loading, high active substance and/or structure stability in acidic environments, mechanical flexibility and strength in an internal orifice (e.g., gastric cavity), easy passage through the GI tract until delivery to at a desired internal orifice (e.g., gastric cavity), and/or rapid dissolution/degradation in a physiological environment (e.g., intestinal environment) and/or in response to a chemical stimulant (e.g., ingestion of a solution that induces rapid dissolution/degradation). The invention relates to a gastric residence structure comprising an active substance, the gastric residence structure comprising: one or more arms comprising a loadable polymeric component, wherein the loadable polymeric component comprises the active substance, and the active substance is a therapeutic agent or a diagnostic agent; an elastic polymeric component; and a separate linker component. The linker connects the one or more arms with the elastic polymeric component, the gastric residence structure is configured to be folded and physically constrained during administration and is configured to assume an open retention shape upon removal of a constraint. A change between the folded shape and the open retention shape is mediated by the elastic polymeric component that undergoes elastic deformation when the residence structure is in the folded shape and recoils when the gastric residence structure assumes the open retention shape. The linker degrades, dissolves, disassociates, or mechanically weakens in a gastric environment which results in loss of retention shape integrity and passage out of a gastric cavity.
Patent NZ-729244-A (NZ)
Title: Methods and systems for chemical vapour sensing
Inventor: PAVEY KARL DAVID
IPC: G08B17/10
Filed: 2014-08-27
Abstract: Active vapour detection devices are often prone to contamination that can result in significant instrument down time and may limit instrument functionality. The present invention relates to a replaceable sensing component for sensing chemical vapours, comprising a housing configured for use with a carrier device, the housing defining an airflow path; a light emitting component; a first substrate positioned so that vapours flowing along the airflow path can contact the first substrate, wherein at least one property of the first substrate changes when it comes into contact with a target vapour, the first substrate also positioned to receive and reflect light emitted by the light emitting component; a second substrate positioned so that vapours flowing along the airflow path can contact the second substrate, wherein at least one property of the second substrate changes when it comes into contact with a target vapour, the second substrate also positioned to receive and reflect light reflected by the first substrate; a sensing element positioned to receive light from the second substrate, the element being configured to detect a change of the at least one property of the first substrate and to produce a signal based on the detected change; and a signal coupling portion to allow output of output signals based on the produced signal to the carrier device.