baber/WOPTO huggingface dataset:
Patent CA-2459348-C (CA)
Title: Anticorps au recepteur p2x7 non fonctionnel, diagnostic et traitement de cancers et d'autres conditions
Inventor: GIDLEY-BAIRD ANGUS
IPC: C12N5/09
Filed: 2002-09-03
Granted: 2013-06-18
Abstract: La présente invention concerne une grande variété de maladies et de conditions, y compris les cancers. L'invention propose une sonde destinée à la détection d'une telle maladie ou condition. La sonde est capable de distinguer entre des récepteurs fonctionnels de P2X¿7? et de récepteurs non fonctionnels de P2X¿7?. La sonde peut établir cette distinction de diverse manières, dont une consiste en la détection d'une modification par rapport à la liaison de l'adénosine triphosphate (ATP) aux récepteurs. L'invention propose également un procédé permettant la détection de la maladie ou condition, utilisant la sonde. L'invention concerne en outre un traitement de la maladie ou condition, au moyen d'un anticorps, ou d'un épitope capable de générer l'anticorps, pouvant établir la distinction entre les récepteurs fonctionnels et non fonctionnels de P2X¿7?. Enfin, l'invention concerne des procédés de traitement, des compositions pharmaceutiques et l'utilisation de la sonde et de l'anticorps
Patent CA-2464525-C (CA)
Title: Array sensor electronics
Inventor: PEINE WILLIAM
IPC: G06F3/041
Filed: 2002-10-24
Granted: 2012-01-10
Abstract: Circuits and methods for detecting and amplifying sensor and sensor array (102, 104) output signals are presented. According to some aspects, a nonlinear feedback loop containing a sensor element provides a nonlinear transformation that compensates for a corresponding nonlinear response of the sensor element thereby providing a linearized final output signal. In other aspects, idle sensors are coupled to a reference on non-idle sensor elements.  Other aspects include sensor and amplification circuits which operate without traditional filtering or switching elements, such that a higher throughput is achieved and no settling time is required due to traditional transients, thus allowing for faster scanning of larger sensor arrays. Some embodiments of the present invention are directed to variable gap capacitive sensor arrays and the signal processing electronics.
Patent CA-2466222-C (CA)
Title: Streamlined body and combustion apparatus having such a streamlined body
Inventor: STAFFLER FRANZ JOSEF
IPC: F23D14/62
Filed: 2002-11-25
Granted: 2010-01-26
Abstract: The invention relates to a streamlined body (1) for influ-encing the flow dynamics of a fluid, wherein the stream-lined body at least partly corresponds to a symmetrically rotated airfoil. A streamlined body (1) of this kind can be used in a number of ways, for example as an impact member, as a flow regulator or as a heat exchanger. It also evens out and accelerates flows. It is used to particular advan-tage in a mixing and reaction chamber for burning fuels.
Patent CA-2469067-C (CA)
Title: Procede de correlation de diagraphies de forage
Inventor: JEFFRYES BENJAMIN PETER
IPC: G01V1/00
Filed: 2002-12-05
Granted: 2013-09-03
Abstract: Cette invention concerne un procédé qui permet de corréler deux ou plusieurs diagraphies de forage superposées produites par un dispositif de diagraphie des puits qui, pendant l'utilisation, est placé dans un puits et fixé à un élément allongé s'étendant le long du puits vers la surface, le mouvement de l'élément allongé à la surface commandant le mouvement du dispositif de diagraphie le long du puits. Le procédé consiste à: a) recevoir des ensembles de données de diagraphie pour deux ou plusieurs diagraphies spatialement superposées produites par le dispositif de diagraphie, chaque ensemble comprenant des mesures d'une caractéristique du puits à des positions espacées dans le sens de la longueur du puits; b) recevoir des données de mesure pour la (les) période(s) de production de diagraphies, ces données de mesure comprenant des mesures de la charge exercée sur l'élément allongé et des mesures de la position de l'élément allongé à la surface; et c) corréler les ensembles de données de diagraphie par détermination d'une conformité de l'élément allongé qui corrige le positions des caractéristiques du puits mesurées. Les corrections apportées à l'étape c) sont effectuées sur la base d'une fonction de correction qui rapporte la position du dispositif de diagraphie à au moins: i) la charge mesurée exercée sur l'élément allongé; ii) la position de l'élément allongé mesurée à la surface; et iii) la conformité de l'élément allongé.
Patent CA-2470246-C (CA)
Title: Process for manufacturing a cellulosic paper product exhibiting reduced malodor
Inventor: SUN TONG
IPC: D21H23/04
Filed: 2002-12-10
Granted: 2010-06-01
Abstract: A process for manufacturing a cellulosic paper product is provided. The process comprises forming an aqueous suspension of papermaking fibers;  introducing a borate compound, preferably boric acid, into the aqueoussuspension; depositing the aqueous suspension onto a sheet-forming fabric to form a wet web; and dewatering and drying the wet web. The process of the present invention provides cellulosic paper products exhibiting a reduced malodor upon re-wetting.
Patent CA-2470346-C (CA)
Inventor: JIANG JIANMIN
IPC: H03M7/30
Filed: 2002-12-24
Granted: 2012-05-01
Abstract: The invention provides a method and apparatus for extracting the luminance and chrominance values of pixels encoded according to MPEG or JPEG encoding using a forward discrete cosine transform (DCT). The invention applies theoretical work to mathematically analyse the forward DCT used in MPEG encoding to derive a set of equations which directly relate a pixel value in an encoded image to one or more of the DCT coefficients obtained via the forward DCT transform in the usual image encoding process. These predetermined equations are used in the invention to allow for extremely fast and computationally efficient extraction of pixel values directly from the DCT coefficients of an encoded pixel block, without having to undergo an inverse DCT transform. The invention is expected to be of use in any application where it is desirable to extract original images from MPEG and JPEG encoded versions in a fast and efficient manner.
Patent CA-2471331-C (CA)
Inventor: CROWLEY MICHAEL WILLIAM
IPC: A47J31/06
Filed: 2004-06-16
Granted: 2007-08-21
Abstract: A timer tea maker is constructed to include an infusion cup carrying a timer, and a link mechanism provided at one side face of the infusion cup and controlled by the timer to raise a stopper from a bottom through hole of the infusion cup for enabling prepared tea to discharge out of the through hole to a tea cup below the infusion cup when the set time has expired.
Patent CA-2475404-C (CA)
Title: Exchanger on turbine ventilation system
Inventor: PALMISANO LAURENT
IPC: F02C1/00
Filed: 2004-07-26
Granted: 2011-09-13
Abstract: The invention relates to a method of supplying cooling air to the hot portions of a turbojet that comprises, from upstream to downstream: a compressor (2); a diffuser (8); a combustion chamber (2); a distributor (13); and a turbine (5) driving said compressor (3), in which method a flow of air (F2) is bled from the flow of air (F1) delivered by the compressor (3), the bled-off flow is cooled in a heat exchanger (22) situated radially outside the combustion chamber (2), and is then directed radially inwards via the stationary blades (14) of the distributor (13) and used for cooling the moving wheel (16) of the turbine (5), the method wherein the flow of cooling air (F2) is bled from the zone (20) of the end of the combustion chamber that surrounds the diffuser (8), and wherein the stationary blades (14) of the distributor (13) are also cooled by a second flow of air (F3) bled from the diffuser.
Patent CA-2482030-C (CA)
Title: Direct dual filing device for sealing agents
Inventor: SPERO RICHARD
IPC: A61B17/00
Filed: 2003-04-18
Granted: 2011-06-21
Abstract: A direct dual filling device for sealing agents capable of transferring a material from a commercially available material container to a material applicator. The filling device of the present invention comprises a hood (12) defining at least one receiving aperture (24), an applicator interface in communication with the hood and having at least one filling port formed thereon, at least one transfer conduit (30A, 30B) in communication with the at least one filling port, at least one withdrawal cannula (32A, 32B) located within the receiving aperture (24) and in communication with the at least one transfer conduit (30A, 30B) and a container support device (14) capable of receiving and supporting at least one material container in an upright tilted position within the receiving aperture (24). The hood (12) may include at least one engaging surface (36) and at least one displacement recess (38). In addition, the container support device (14) may include at least one biasing member (70) capable of biasing the material container from an upright position to an upright tilted position, thereby enabling the withdrawal of substantially all the material from the material container.
Patent CA-2483622-C (CA)
Inventor: MEUTERMANS WIM
IPC: C07H17/04
Filed: 2003-04-24
Granted: 2012-01-03
Abstract: L'invention concerne des procédés de préparation de bibliothèques combinatoires de composés de disaccharide potentiellement actifs au plan biologique. Ces composés sont fonctionnalisés de diverses manières, en vue de varier la liposolubilité, la taille, la fonction et d'autres propriétés, dans le but particulier de découvrir des nouveaux composés médicamenteux ou de type médicamenteux, ou des composés présentant des propriétés utiles. L'invention porte également sur des intermédiaires, des procédés et des stratégies synthétiques pour la synthèse en solution ou en phase solide de disaccharides, fonctionnalisés de manière différentes autour du cycle sucre, comprenant l'addition de l'aromaticité et de la charge, ainsi que le placement de groupes utiles au plan pharmaceutique et d'isostères.
Patent CA-2483632-C (CA)
Title: Flag holder for reducing fraying of flag
Inventor: SPIEGEL H JAY
IPC: G09F17/00
Filed: 2003-05-12
Granted: 2010-09-28
Abstract: A flag holder designed to reduce the fraying of the trailing edge of a flag (10) supports a flag with an upper fitting (4, 6) and a lower fitting (20). The upper fitting may be fixed (4) with respect to the flagpole (1) or, if desired, may rotate (53) with respect to the flagpole (1). However, the upper fitting may not reciprocate with respect to the flagpole (1). The lower fitting (20) may freely reciprocate with respect to the flagpole (1) and, if desired, may be rotatable with respect to the flagpole (1). As soon as wind conditions exceed a desired threshold, the lower fitting (20) begins to rise up the flagpole (1), moved by flexing of the flag, until it arrives at the location of the upper fitting (4, 6, 53), causing the body of the flag to assume an elongated generally U-shaped configuration which drastically reduces the snapping effect that would otherwise cause fraying of the downstream edge (14) of the flag. As soon as wind conditions reduce, the lower fitting (20) automatically lowers, causing the flag (10) to be fully opened again.
Patent CA-2487485-C (CA)
Inventor: NISHIYAMA SHINYA
IPC: F16D1/09
Filed: 2004-11-15
Granted: 2009-11-03
Abstract: The present invention relates to a mounting structure for mounting firmly onto a rotating shaft a rotational force transmission member such as a chain sprocket, a gear, a belt pulley and the like. A drive sprocket as a rotational force transmission member is fitted into an end of the rotating shaft in a splined manner; a coned disc spring and a washer are stuck in sequence onto a face at the outer end of the rotational force transmission member; and the coned disc spring and the washer are supported and sandwiched by the screw fastening member to be screwed to an end of the rotating shaft and the rotational force transmission member.
Patent CA-2494197-C (CA)
Title: Streptococcus uberis protein, nucleic acid sequence encoding the same and its use in a mastitis vaccine
Inventor: HENSEN SELMA MARIANNE
IPC: C12Q1/68
Filed: 2003-08-06
Granted: 2012-10-09
Abstract: The present invention relates to nucleic acid sequences encoding a 22.5 kD Streptococcus uberis protein and to parts of such nucleic acid sequences that encode an immunogenic fragment of such proteins, and to DNA fragments, recombinant DNA molecules, live recombinant carriers and host cells comprising such nucleic acid sequences or such parts thereof. The invention also relates to a 22.5 kD Streptococcus uberis protein and immunogenic parts thereof encoded by such sequences. Furthermore, the present invention relates to vaccines comprising such nucleic acid sequences and parts thereof, DNA fragments, recombinant DNA molecules, live recombinant carriers and host cells comprising such nucleic acid sequences or such parts thereof, proteins or immunogenic parts thereof and antibodies against such proteins or immunogenic parts thereof. Also, the invention relates to the use of said proteins in vaccines and for the manufacture of vaccines. Moreover, the invention relates to the use of said nucleic acid sequences, proteins or antibodies for diagnostic or vaccination purposes. Finally the invention relates to diagnostic kits comprising such a nucleic acid, protein or antibodies against such protein.
Patent CA-2502431-C (CA)
Inventor: SCHATZ OCTAVIAN
IPC: C12P19/34
Filed: 2003-10-17
Granted: 2013-04-02
Abstract: A method is described for manufacture of a nucleic acid molecule comprising providing a first at least partially double-stranded oligonucleotide comprising a recognition site for a first IIS restriction enzyme, and a single-stranded overhang. A second at least partially double-stranded oligonucleotide is provided, comprising a recognition site for a second IIS restriction enzyme, and a single-stranded overhang. The first and the second oligonucleotides are ligated via their overhangs, generating a first ligation product that is immobilised to a surface. This product is cut with the first enzyme, releasing an elongated oligonucleotide. The elongated oligonucleotide is combined with a further double--stranded oligonucleotide having a recognition site for a further IIS restriction enzyme. The elongated oligonucleotide and the further double-stranded oligonucleotide are ligated, forming a further ligation product that is immobilized to a surface. The further ligation product is cut with the further IIS enzyme, releasing an elongated oligonucleotide having an overhang.
Patent CA-2504082-C (CA)
Inventor: KRISTIANSEN FREDDY
IPC: G06F9/44
Filed: 2005-04-13
Granted: 2012-02-07
Abstract: A method, computer readable medium and system are provided which generate a model driven form user interface to represent an application model. The method includes selecting which of multiple different logical form types to use to generate the form user interface to represent the application model. The method also includes providing a first map. A display target independent logical form is generated using the application model, the selected form type and the first map.
Patent CA-2515146-C (CA)
Inventor: BLONDINO FRANK E
IPC: A61K31/485
Filed: 2003-12-15
Granted: 2011-12-06
Abstract: A liquid aerosol formulation comprising at least one thermally stable active ingredient selected from the group consisting of buspirone, buprenorphine, triazolam, cyclobenzaprine, zolpidem, pharmaceutically acceptable salts and esters thereof and derivatives thereof. The liquid formulation can include an organic solvent such as propylene glycol and one or more optional excipients. The active ingredient can be present in an amount of 0.01 to 5 wt. % and the formulation can be heated to provide a vapor which forms an aerosol having a mass median acrodynamic diameter of less than 3 um.
Patent CA-2519249-C (CA)
Title: Method and system for determining insulin dosing schedules and carbohydrate-to-insulin ratios in diabetic patients
Inventor: HEBBLEWHITE HARRY
IPC: A61M15/00
Filed: 2004-03-19
Granted: 2012-11-27
Abstract: Method for digitally determining the daily insulin regimen for a diabetic patient. The invention divides the patient's day into adjustable time intervals containing basal insulin dosage rates and Carbohydrate-to-Insulin Ratio(s) (for determining meal insulin doses). The invention identifies the Corrective Insulin doses over a time interval as an "error" in the Prescription Insulin (Basal Insulin + Meal Insulin). Methods involve first estimating the change to one of these two components of Prescription Insulin, and then determining the change to the other by subtracting from the error. One method estimates Change in Meal Insulin distributed among intervals proportional to old Meal Insulin. Another method lumps After-Meal Corrective Insulin together with Meal Insulin. Another method splits the interval at the After-Meal Corrective Dose and determines Basal from Time-Boundary Corrective Dose. Data may be obtained from the previous day, and a small fraction of error applied, leading to asymptotic reduction of error. Data may be obtained from recent history, and a larger fraction of error applied by doctor or automatic method.
Patent CA-2526437-C (CA)
Title: Procede et systeme de transmission de donnees d'utilisateur au moyen d'une liaison etablie par composition dans un reseau de communication
Inventor: BRITSCH MATTHIAS
IPC: H04W84/08
Filed: 2004-05-19
Granted: 2013-04-23
Abstract: La présente invention se rapporte à un procédé permettant de transmettre des données d'utilisateurs au moyen d'une connexion établie en service à numérotation dans un réseau de communication radio, qui se caractérise en ce que les données d'utilisateurs sont transmises sous forme de paquets de données spécialisés lors de la libération commandée. L'invention concerne un domaine spécialisé de communication à l'alternat par bouton poussoir qui héberge des noeuds de réseau de service à boutons poussoir (PTT SNN) ainsi que des serveurs d'application (AS):
Patent CA-2527618-C (CA)
Inventor: CHAUMAT PIERRE
IPC: C12M1/26
Filed: 2005-11-21
Granted: 2013-02-12
Abstract: The invention concerns a device for collecting cores 1 intended for the construction of tissue arrays of the type including a collection punch 5 for core samples, a core punch 6 to hollow out one or several blocks called receivers and a means to eject 7 cores collected in one or several paraffin receiver blocks or in any medium, frozen or not. The core punch 6 is mounted essentially coaxially in the collection punch 5, the collection punch being in an external position, the two punches 5, 6 being mobile in translation and/or rotation in relation to one another and the means of ejection being arranged to eject the cores from each punch.
Patent CA-2536735-C (CA)
Inventor: HARDING FIONA A
IPC: C12N7/00
Filed: 2004-08-23
Granted: 2013-01-22
Abstract: The present invention provides means to identify functional CD8+ T-cell epitopes in any protein of interest. The present invention further provides CD8+ T-cell epitopes of various proteins. In additional embodiments, the present invention provides epitopes suitable for use in prophylactic and/or therapeutic vaccines. In particularly preferred embodiments, the present invention provides modified epitopes suitable for use in prophylactic and/or therapeutic vaccines. In some preferred embodiments, the present invention provides means for the development of HPV vaccines, in particular multivalent vaccines for the prevention of infection with high-risk HPV strains. In particular, the present invention provides means to identify CD8+ T-cell epitopes in HPV strains such as HPV 16 and HPV 18. In additional embodiments, the present invention provides means for the development of therapeutic vaccines against high-risk HPV types that prevent the development of benign and/or malignant tumors in infected individuals. The present invention further provides epitopes suitable for use in prophylactic and therapeutic vaccines.
Patent CA-2539097-C (CA)
Inventor: ARONSTAM PETER S
IPC: E21B10/60
Filed: 2004-09-13
Granted: 2010-03-23
Abstract: A drilling system includes a steerable bottOmhole assembly (BHA) having a steering unit and a control unit that provide dynamic control of drill bit orientation or tilt. Exemplary steering units can adjust bit orientation at a rate that approaches or exceeds the rotational speed of the drill string or drill bit, can include a dynamically adjustable articulated joint having a plurality of elements that deform in response to an excitation signal, can include adjustable independently rotatable rings for selectively tilting the bit, and/or can include a plurality of selectively extensible force pads. The force pads are actuated by a shape change material that deforms in response to an excitation signal. A method of directional drilling includes continuously cycling the position of the steering unit based upon the rotational speed of the drill string and/or drill bit and with reference to an external reference point.
Patent CA-2539277-C (CA)
Inventor: KUESTERS ERNST
IPC: A61K31/135
Filed: 2004-10-14
Granted: 2013-04-23
Abstract: Disclosed are compounds of formula (I):   (see formula I) wherein R1, R2, R5 and R6 are as defined in the claims; such compounds may be used in the prevention or treatment of organ or tissue transplant rejection, or an autoimmune disease or inflammatory condition.
Patent CA-2546390-C (CA)
Title: Two-stage pressure relief valve
Inventor: FENNY CARLOS A
IPC: F16K17/04
Filed: 2004-10-27
Granted: 2009-03-10
Abstract: A two-stage pressure relief valve for use with hydraulic systems is disclosed. The two-stage pressure relief valve has a first stage that relieves increases in hydraulic system pressure over the normal operating pressure and up to a selected threshold pressure level, and a second stage that brings the hydraulic system pressure down to a selected reduced operating pressure that is below the normal operating pressure in response to increases in the operating pressure over the threshold pressure level.
Patent CA-2547223-C (CA)
Inventor: DELGADO EMIL
IPC: C09K8/62
Filed: 2006-05-17
Granted: 2013-03-19
Abstract: Liquid hydrocarbons are gelled by the introduction of a phosphate ester and a crosslinking agent for use in oil recovery. Generally a proppant, delayed gel breaker and other modifiers are added to the gelled hydrocarbon to improve the oil recovery process. The phosphate ester used in this method and composition for oil recovery has low volatility and good stability during hydrocarbon distillation resulting in improved distillation efficiency in a refinery.
Patent CA-2548122-C (CA)
Inventor: OUWENDIJK-VRIJENHOEK MAARTJE
IPC: C11D3/50
Filed: 2004-11-25
Granted: 2013-01-15
Abstract: The present invention provides a liquid detergent composition comprising an effective amount of an enzyme, 0.001-3% wt of a perfume ingredient, and 0.005-2% wt of an anti-oxidant. It has been found that the storage stability of the enzyme -which is preferably a protease- can be drastically improved by the addition of the anti-oxidant.
Patent CA-2549626-C (CA)
Inventor: SEVERANCE WAYNE STANLEY JR
IPC: H05H1/34
Filed: 2006-06-06
Granted: 2013-01-15
Abstract: An electrode system for a plasma torch is provided, comprising a first electrode holder configured in a first cutting arrangement and adapted to cut a thinner workpiece. The first electrode holder is configured to receive a first electrode assembly comprising a holder element having an emissive insert element received therein. A second electrode holder is configured in a second cutting arrangement and is adapted to cut a thicker workpiece. The second electrode holder is interchangeable with the first electrode holder, with respect to the plasma torch. The second electrode holder is further configured to receive a second electrode assembly comprising a pencil element. The interchangeable first and second electrode holders thereby allow a single plasma torch to cut both the thinner and thicker workpieces. An associated electrode system and an electrode device are also provided.