baber/WOPTO huggingface dataset:
Patent CA-3080239-A1 (CA)
Inventor: CAMPBELL NOLAN ROBERT
IPC: C07K16/46
Filed: 2018-10-25
Abstract: Provided herein, in some embodiments, are methods for reducing the risk of developing progressive multifocal leukemia in patients undergoing natalizumab therapy by switching to an extended interval dosing (EID) schedule.
Patent CA-3081393-A1 (CA)
Title: Process for producing acetoxy-bearing siloxanes
Inventor: KNOTT WILFRIED
IPC: C08G77/46
Filed: 2020-05-26
Abstract: Described is a process for producing preferably trifluoromethanesulfonic acid-acidified, end-equilibrated, acetoxy-bearing siloxanes which comprises reacting cyclic siloxanes, in particular comprising D4 and/ or D5, and/or cyclic branched siloxanes of the D/T type with acetic anhydride using preferably trifluoromethanesulfonic acid as catalyst and with addition of acetic acid, wherein the cyclic branched siloxanes of the D/T type are mixtures of cyclic branched siloxanes of the D/T type which may contain not only siloxanes comprising D and T units but also siloxanes comprising Q units.
Patent CA-3085707-A1 (CA)
Title: System and method for dedicated storage, through a secure internet connection, in a remote location
Inventor: HOFFMAN JEFFREY ROBERT
IPC: H04L9/14
Filed: 2020-07-06
Abstract: A system and method for providing dedicated storage through a secure internet connection in a remote location are disclosed. The system and method form an "anti-cloud system" by storing an end user's data only in a location over which the end user has both logical and physical control.  Data within this system and method are stored on a primary block device and on a secondary block device that is mirrored at the start for redundancy and these drives are under both the logical and physical control of the end user. These specific block devices do not contain data from any other end user and therefore the specific end user is in possession of all copies.  Should the specific end user wish to destroy all of his/her data, the destruction of the two block devices will guarantee that no other copies of his/her data are extant.
Patent CA-3086329-A1 (CA)
Title: Climate control system for insect farming
Inventor: JANSEN JACO
IPC: A01K67/033
Filed: 2018-12-21
Abstract: The invention relates to a climate control device for controlling the temperature and humidity of air supplied to colonies of insects cultured in an industrial scale insect farm. In particular, the invention relates to a controllable air conditioning system comprising a network of pipes connecting at least one cluster comprising at least one insect farming cage, such that air is conditionable in the cages at the cluster level. More specifically, the invention relates to a system comprising a central main air conditioning facility providing temperature conditioned air and absolute air humidity conditioned air to each of a number of local air conditioning devices, each separate local air conditioning device providing temperature conditioned air and absolute air humidity conditioned air to each of a plethora of clusters of insect breeding cages separately, said cages housed in an temperature conditioned farming room. This way, insects in cages housed in farming rooms are farmed under improved conditions with regard to minimized cage-to-cage temperature differences and differences in relative air humidity, due to the use of the climate control device of the invention.
Patent CA-3086576-A1 (CA)
Inventor: ROSSI FILIPPO
IPC: A47G33/00
Filed: 2020-07-13
Abstract: A funerary containment structure for funerary objects, which comprises a base structure, which defines at least one niche, which is designed to contain at least one funerary object and has at least one access opening, which is closed by way of at least one slab which is fixed to the base structure; at least one auxiliary device which has a supporting body which is connected to the base structure and supports at least one supporting arm, which extends laterally from the supporting body; fixing elements for fixing at least one ornamental object to the free end of the supporting arm are furthermore provided.
Patent CA-3086907-A1 (CA)
Title: Systeme d'eclairage portable interactif
Inventor: LAY JORDAN
IPC: H05B44/00
Filed: 2019-01-07
Abstract: Un système d'éclairage interactif comprend un groupe d'une ou de plusieurs lampes portables conçues pour répondre à la manipulation spatiale de l'utilisateur d'une lampe pour commander le système. Les lampes peuvent être reliées de manière sans fil pour fonctionner à l'unisson, et chaque lampe peut également comprendre un capteur de lumière ambiante, ce qui aide le système à optimiser les caractéristiques et le profil d'éclairage.
Patent CA-3087115-A1 (CA)
Title: Uses of compounds in preparation of medicament for treating cerebral small vessel disease
Inventor: YAN GUANGMEI
IPC: A61P9/10
Filed: 2018-12-28
Abstract: Disclosed is the use of compounds of formula I: (see formula I) a deuterated compound or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for the treatment of cerebral small vessel disease in a patient, wherein R1 is H, an alkyl having 1 to 5 carbon atoms, or -CH(CH3)(CH2)3CH(CH3)2. The cerebral small vessel disease is preferably cerebral microbleed. The cerebral microbleed is spontaneous cerebral microbleed, drug-related cerebral microbleed, or traumatic cerebral microbleed. The present invention demonstrates that these compounds significantly enhance the clearance of extravascular hemoglobin, and thus can be used to treat cerebral small vessel disease.
Patent CA-3091468-A1 (CA)
Title: Use of anti-human sirpa v1 antibodies and method for producing anti-sirpa v1 antibodies
Inventor: POIRIER NICOLAS
IPC: A61K39/00
Filed: 2019-03-13
Abstract: The invention is in the field of immunotherapy. The present invention provides antibodies useful in therapeutic and diagnostic applications targeting human SIRPa, said antibodies enhancing the cross-presentation of antigens to T cells. The invention also provides antibodies against specific isoforms of SIRP a and able to disrupt the interaction between those isoforms of SIRP a and human CD47 for use in treating or preventing a disease, or diagnostic applications, and methods for producing and/or selecting anti-human SIRPa antibodies that bind with different affinities to various isoforms of human SIRP members.
Patent CA-3091613-A1 (CA)
Inventor: KOH GOU YOUNG
IPC: C07K16/22
Filed: 2019-02-19
Abstract: The present invention relates to mouse antibodies that bind to angiopoietin-2 (Ang2), humanized anti-Ang2 antibodies derived therefrom, and the use thereof. The anti-Ang2 antibodies have a dual function of activating the Tie2 receptor together with neutralizing Ang2. The anti-Ang2 antibodies show the property of normalizing abnormal and pathological blood vessels, and thus exhibits therapeutic efficacy against various diseases and disorders associated with abnormal blood vessels. The present invention provides an angiogenesis inhibitor and a composition for prevention and treatment of diseases associated with abnormal Ang2 expression and Tie2 dysregulation, which comprise the antibody as an active ingredient, and a composition for diagnosing diseases associated with Ang2 inhibition and Tie2 activation, which comprises the antibody.
Patent CA-3092502-A1 (CA)
Title: Vented ring and method of manufacturing the same
Inventor: GOODWIN PETER
IPC: A44C27/00
Filed: 2019-03-15
Abstract: Vented ring 10 includes an outer ring portion 11, an inner ring portion 12, and an anti-stretch element 50 positioned between the outer ring portion 11 and the inner ring portion 12. The inner ring portion 11 includes lateral grooves 15a connected to inner grooves 16 to form at least one fluid conduit from a first side 12a to a second side 11a of the vented ring 10. The method includes injecting a first material into a first mold to form an outer ring portion, injecting a second material into a second mold to form an inner ring portion 12, and positioning an anti-stretch element 50 between outer and inner ring portions 11, 12. The second mold includes at least one feature on a surface thereof corresponding to connected lateral grooves 15a and inner grooves 16 on an inner surface of the inner ring portion 12.
Patent CA-3093198-A1 (CA)
Inventor: TRIANA-BALTZER GALLEN
IPC: C07K16/18
Filed: 2019-03-04
Abstract: L'invention concerne des procédés de mesure de la quantité de protéine tau p217 + phosphorylée ou multiphosphorylée dans un échantillon. L'invention concerne également des procédés de détection ou de diagnostic de tauopathies, des procédés de détermination de l'efficacité d'un traitement d'une tauopathie, et des procédés permettant de déterminer si un sujet est approprié pour une thérapie par anticorps anti-p217+ tau. L'invention concerne également des anticorps destinés à être utilisés dans les procédés et des kits comprenant les anticorps.
Patent CA-3094173-A1 (CA)
Title: Intestinal alkaline phosphatase formulations
Inventor: BRISTOL ANDREW
IPC: A61K38/46
Filed: 2019-03-20
Abstract: The present invention provides for a formulation comprising an active alkaline phosphatase (AP)-based agent and an enteric agent, wherein the formulation is suitable for releasing a substantial amount of the active AP-based agent in the intestines.
Patent CA-3097880-A1 (CA)
Title: Assistance motorisee amovible pour fauteuil roulant manuel
Inventor: PESKIN EVAN
IPC: A61G5/04
Filed: 2019-04-26
Abstract: L'invention concerne un dispositif pour transformer un fauteuil roulant manuel en un fauteuil roulant électronique. Le dispositif comprend une manette de commande, une unité de communication, un moteur, un galet à friction rétractable, une unité de mise en prise et une source d'alimentation. La manette de commande est fonctionnellement connectée à une unité de communication. L'unité de communication est fonctionnellement connectée à un moteur. Le moteur comprend un arbre relié à un rotor. Le galet à friction rétractable est monté sur l'arbre. Le galet est placé en contact avec une roue d'un fauteuil roulant manuel. L'unité de mise en prise est fixée au fauteuil roulant manuel pour attacher de manière amovible le galet à friction et la roue. La source d'alimentation est fonctionnellement connectée au moteur et à la manette de commande.
Patent CA-3098663-A1 (CA)
Inventor: SHIMIZU HIDEO
IPC: C07F15/00
Filed: 2019-05-08
Abstract: La présente invention concerne : un procédé de conversion d'un groupe hydroxyle d'un alcool ; et un catalyseur rendant possible le procédé. Un procédé de conversion d'un groupe hydroxyle d'un alcool selon la présente invention est caractérisé par la production d'un composé représenté par CH(R1)(R2)Nu (dans laquelle R1, R2 et Nu sont tels que définis ci-dessous) par la mise en réaction d'un alcool représenté par CH(R1)(R2)OH (dans laquelle chacun de R1 et R2 représente un atome d'hydrogène, un groupe alkyle éventuellement substitué, ou similaire) et d'un composé ayant un proton actif, qui est représenté par H-Nu (Nu étant un groupe représenté par -CHX1-EWG1 ou -NR3R4 ; X1 représente un atome d'hydrogène ou similaire ; EWG1 représente un groupe attracteur d'électrons ; et chacun de R3 et R4 représente un atome d'hydrogène, un groupe alkyle éventuellement substitué, ou similaire), les uns avec les autres en présence d'un complexe d'un métal du groupe 7-11 du tableau périodique des éléments et d'au moins une base solide choisie dans le groupe constitué par des doubles hydroxydes en couches, des oxydes composites et d'hydroxyde de calcium.
Patent CA-3100766-A1 (CA)
Title: Anti-ox40 antibodies and methods of use
Inventor: LIU YE
IPC: A61P37/02
Filed: 2019-05-22
Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that bind to human OX40 (ACT35, CD134, or TNFRSF4), a pharmaceutical composition comprising said antibody, and use of the antibody or the composition for treating a disease, such as cancer. In particular, the anti-OX40 antibody of the present invention does not interfere with the binding of OX40-ligand to its receptor.
Patent CA-3101850-A1 (CA)
Title: Plaque de tete de vadrouille comprenant des ailettes pivotantes
Inventor: BRUGORA ALESSANDRO
IPC: A47L13/258
Filed: 2019-05-16
Abstract: L'invention concerne une plaque de nettoyage (1) comprenant un corps de base (2) auquel sont reliées de manière pivotante une première ailette de plaque de nettoyage (3), une seconde ailette de plaque de nettoyage (4) et une articulation (5), les ailettes de plaque de nettoyage (3), (4) pouvant pivoter entre une position de travail (6) et une position d'essorage (7), un dispositif (8) destiné à bloquer l'articulation (5) qui fixe l'articulation (5) le long de l'axe longitudinal (9) de l'articulation étant associé au corps de base (2), lorsque les ailettes de plaque de nettoyage (3, 4) se situent en dehors de la position de travail (6).
Patent CA-3103863-A1 (CA)
Inventor: MARS DENIS
IPC: H04W12/08
Filed: 2019-06-17
Abstract: A system includes a device having a short-range transceiver for capturing ephemeral ID signals within a geographic region proximate thereto, and for detecting an ephemeral ID signal output from a user device, wherein the ephemeral ID signal does not include personally identifiable information of the user, a wide-area network interface for transmitting a portion of the ephemeral ID signal and a first identifier associated with the device to a remote server associated with the ephemeral ID signals, and for receiving a first reply from the remote server in response to the portion of the ephemeral ID signal and the first identifier associated with the device, and an output unit for providing an electronic authorization signal to a first external unit coupled to the device in response to the first reply, wherein the first external unit is configured to perform a first physical action in response to the first reply.
Patent CA-3104549-A1 (CA)
Title: Ressentis virtuels multimodaux de contenu distribue
Inventor: HOWARD TODD
IPC: G06F3/01
Filed: 2018-06-22
Abstract: La présente invention concerne des systèmes et des techniques destinés à fournir à un spectateur, via une interface d'utilisateur sur un dispositif de ressenti d'utilisateur, un ressenti virtuel à facettes multiples et à dimension souple d'une ou plusieurs identités cibles placées dans un contexte de sujet. Un aspect de système comprend les actions de sélectionner, de trouver et d'interpréter un contenu numérique se rapportant à un contexte de sujet indiqué par le spectateur; de décomposer un contenu numérique en éléments de contenu discrets contenant des segments de contenu qui sont classifiés selon un schéma de facettes d'éléments, puis à construire un référentiel segmenté en facettes d'éléments de contenu discrets se rapportant à une identité cible; compléter un contenu numérique existant par des informations et du contenu complémentaires pour soutenir la présentation d'un contenu d'information, de dimensions, ou de capacités sensorielles étendues; et créer et présenter un conteneur de ressenti virtuel qui est adapté au spectateur et aux capacités du dispositif de ressenti d'utilisateur du spectateur.
Patent CA-3104606-A1 (CA)
Inventor: KAKISHIMA YUICHI
IPC: H04W16/28
Filed: 2018-06-28
Abstract: A user terminal (20) comprises: a receiving unit for receiving a first wireless signal transmitted by a first transmission point using a first wireless resource and a second wireless signal transmitted by a second transmission point using a second wireless resource; and a control unit for controlling reception processing of the first wireless signal transmitted by the first transmission point using the first wireless resource and the second wireless signal transmitted by the second transmission point using the second wireless resource assuming that the first wireless resource and the second wireless resource are allowed to be set to at least one of mutually different times and mutually different frequency bands.
Patent CA-3105779-A1 (CA)
Inventor: DACOSTA ALBERT
IPC: A61B17/17
Filed: 2019-07-11
Abstract: Bone fusion system, devices, guide, implant and methods for using the bone fusion system, devices, guide and implant are disclosed. The fusion system includes an alignment guide and an implant. The alignment guide couples to the implant. The alignment guide includes a body, a fixation member engaging a first end of the body, and a tissue protector engaging a second end of the body. The implant includes a body portion, an extension portion extending away from a first end of the body portion, a curved portion extending away from a second end of the body portion, and a foot member extending away from the curved portion perpendicular to the body portion. Finally, methods for using the bone fusion system, devices, guide and implant are disclosed.
Patent CA-3105981-A1 (CA)
Inventor: PEDRETTI ANDREA
IPC: B66C1/54
Filed: 2019-07-10
Abstract: A an energy storage system (100, 100a) includes a crane (101) and a plurality of blocks (150), where the crane is operable to move blocks from a lower elevation to a higher elevation (via stacking of the blocks) to store electrical energy as potential energy of the blocks, and then operable to move blocks from a higher elevation to a lower elevation (via unstacking of the blocks) to generate electricity based on the kinetic energy of the block when lowered (e.g., by gravity).
Patent CA-3106956-A1 (CA)
Title: Systems and methods for configurable ordered transformation of database content
Inventor: WATTS SEAN WILLIAM
IPC: G06F16/90
Filed: 2021-01-25
Abstract: A system includes processor hardware and memory hardware that stores instructions. The instructions include, in response to receiving a request, determining a request type of the request, retrieving a first set of collected information, and selecting a first set of instructions corresponding to the request type. The instructions include constructing a first result by executing each instruction of the first set of instructions to create the first entry as a nested entry within the first result including data of the first set of collected information identified in the first set of instructions as nested or retrieve first data of the first set of collected information identified by the first instruction and add the first data to the first entry of the first result. The instructions include transforming a display of the operator device to complete a set of fields displayed on the display with corresponding entries of the first result.
Patent CA-3107166-A1 (CA)
Title: Detachable wheel assembly
Inventor: THOMPSON GENE
IPC: B60B33/00
Filed: 2021-01-22
Abstract: ABSTRACT OF THF n1saosuRE A detachable wheel i=iernbly having a clamp, a first translation a.ssembly coupled to the clamp and a slide assembly coupled to the clamp. The wheel assembly further includes a second translation assembly coupled to the lide assembly, an axle coupled to the SP.Conii translation assornbly, and a wheel coupled to the axle. I he wheel assembly is attached to support of a structure and one or more ol the translation assemblies or the slide assemblies are manipulated to lift the str ucture off the Eround. Once the structure is off the ground, the structure can be moved via the wheel on the axle. 26 Date Recue/Date Received 2021-01-22
Patent CA-3107512-A1 (CA)
Title: Systemes et procedes de verification personnelle pour des livraisons par vehicule autonome
Inventor: FERGUSON DAVID
IPC: G06F3/01
Filed: 2019-07-29
Abstract: Selon certains aspects la présente invention concerne un véhicule autonome robotisé. Selon divers modes de réalisation, le véhicule autonome robotisé comprend un système de transport, un compartiment sécurisé configuré pour se verrouiller et se déverrouiller de manière autonome, le compartiment sécurisé contenant un article à distribuer à un individu particulier, un lecteur d'identification personnel, au moins un processeur et une mémoire stockant des instructions. Les instructions, lorsqu'elles sont exécutées par le(s) processeur(s), amènent le véhicule autonome robotisé à se déplacer de manière autonome vers un emplacement de destination de l'individu particulier, à capturer par le lecteur d'identification personnel à l'emplacement de destination un objet d'identification personnel, à déterminer que l'objet d'identification personnel capturé correspond à une identité de l'individu particulier, et à déverrouiller le compartiment sécurisé sur la base de la détermination.
Patent CA-3109774-A1 (CA)
Title: Methodes de reduction du besoin de revascularisation arterielle peripherique chez un sujet traite par des statines
Inventor: GRANOWITZ CRAIG
IPC: A61K31/232
Filed: 2019-08-15
Abstract: Dans divers modes de réalisation, la présente invention concerne des méthodes de diagnostic d'un besoin de revascularisation artérielle périphérique et/ou de réduction d'un besoin de revascularisation artérielle périphérique chez un sujet par l'administration au sujet d'une composition pharmaceutique comprenant d'environ 1 g à environ 4 g d'un ester éthylique de l'acide eicosapentaénoïque ou d'un dérivé de celui-ci.
Patent CA-3110527-A1 (CA)
Title: Venting system for a mixing apparatus
Inventor: FLETCHER THOMAS REID
IPC: B01F23/80
Filed: 2019-08-30
Abstract: A filter unit for a mixing apparatus includes a hydrophilic filter and a hydrophobic vent filter. The hydrophilic filter is configured to receive a fluid including a liquid and gas. The hydrophilic filter is further configured to sterilize the liquid. The hydrophobic vent filter is configured to receive the gas from the hydrophilic filter. The hydrophobic vent filter further includes a vent and a membrane configured to separate an interior of the filter unit from an exterior of the filter unit, the gas being vented from the filter unit by flowing across the membrane and out of the vent. In some embodiments, the filter unit further includes a defoaming device configured to receive gas, foam comprised the liquid containing trapped gas, and some of the liquid from the hydrophilic filter and is further configured to release at least some of the gas from the foam.
Patent CA-3112819-A1 (CA)
Inventor: BLASCO MARHUENDA MARIA ANTONIA
IPC: A61K45/06
Filed: 2018-09-13
Abstract: The invention provides TRF1 inhibitors and compositions comprising them for the treatment of a brain cancer, such as a glioblastoma, and particularly a glioblastoma multiforme (GBM). PI3K inhibitors can be among the TRF1 inhibitors used. The compositions can comprise more than one TRF1 inhibitor, being particularly advantageous that at least one of the inhibitors is a PI3K inhibitor and that at least a second possible TRF1 inhibitor present is selected from the group an RTK inhibitor, a MEK inhibitor, an ERK inhibitor, an HSP90 inhibitor, docetaxel and gemcitabine, because such compositions show a synergic effect. The invention also relates to a method for identifying compounds candidates to be used for treating glioblastoma or other cancers, which method is based on the identification of the compound as a TRF1 inhibitor.
Patent CA-3114887-A1 (CA)
Inventor: SORKIN FELIX
IPC: E04C5/12
Filed: 2021-04-13
Abstract: A closure assembly includes a section of duct, a duct coupler assembly, a closure load plug, and an end cap. The duct coupler assembly is fit against the section of duct. The closure load plug is mechanically connected to the duct coupler assembly. The end cap is mechanically connected to the closure load plug.
Patent CA-3120048-A1 (CA)
Inventor: LUISE MASSIMO
IPC: A47B53/02
Filed: 2019-11-28
Abstract: An archive (1000) comprising at least one prismatic box- shaped container (1) movable on guides extending in a given direction (D) to create a compactable archive (1000); the container (D comprising a plurality of substantially rectangular walls (4) which are connected end to end in a fluid-tight manner to delimit a volume (VL) accessible according to the direction (D) through at least one opening (A)(A'); peripheral frame members (20) being carried frontally by the walls (4) adapted to determine, in use, a fluid-tight closing condition of the volume (VL).