baber/WOPTO huggingface dataset:
Patent IL-142499-A0 (IL)
Title: Building units for synthesis of backbone cyclized peptide analogs
IPC: C07K14/655
Filed: 2001-04-06
Abstract: PCT No. PCT/IB95/00455 Sec. 371 Date Dec. 5, 1996 Sec. 102(e) Date Dec. 5, 1996 PCT Filed Jun. 8, 1995 PCT Pub. No. WO95/33765 PCT Pub. Date Dec. 14, 1995Novel backbone cyclized peptide analogs are formed by means of bridging groups attached via the alpha nitrogens of amino acid derivatives to provide novel non-peptidic linkages. Novel building units disclosed are N alpha ( omega -functionalized)amino acids constructed to include a spacer and a terminal functional group. One or more of these N alpha ( omega -functionalized) amino acids are incorporated into a peptide sequence, preferably during solid phase peptide synthesis. The reactive terminal functional groups are protected by specific protecting groups that can be selectively removed to effect either backbone-to-backbone or backbone-to-side chain cyclizations. The invention is exemplified by backbone cyclized bradykinin antagonists having biological activity. Further embodiments of the invention are somatostatin analogs having one or two ring structures involving backbone cyclization.
Patent IL-142973-A0 (IL)
Title: Process for preparing piperidines
IPC: C07D211/02
Filed: 2001-05-04
Abstract: Piperidine derivatives are produced from activated pyridine derivatives by catalytic hydrogenation in the presence of a palladium-on-carbon catalyst and an aromatic hydrocarbon solvent.
Patent IL-159157-A0 (IL)
Title: Rotary slot milling cutter and cutting insert therefor
IPC: B23C5/08
Filed: 2003-12-02
Abstract: A rotary slot milling cutter has a plurality of cutting portions, each cutting portion having an insert pocket and a cutting insert removably mounted therein. The cutting insert includes a top face and a bottom face which has two spaced-apart abutments, with a ceiling formed therebetween. The insert pocket has a generally axially disposed pocket base provided with two support surfaces and a radially extending rib disposed therebetween, the rib having a roof and two banks. When the cutting insert is mounted in the insert pocket, the abutment platforms abut the support surfaces, and a gap exists between the roof of the rib and the ceiling, and between each side-slope and adjacent banks.
Patent IL-160332-A0 (IL)
Title: Pressure regulator
IPC: A61M5/142
Filed: 2002-08-14
Abstract: A variable device for regulating the outlet pressure of a fluid from a valve body, includes a pressure-sensing chamber having a wall formed by a resilient self-restoring diaphragm which is responsive to pressure in the chamber. A valve element connected to the diaphragm controls flow into the chamber. Increased pressure in the chamber decreases the flow into the chamber and decreasing pressure increases flow whereby fluid flow out from the chamber is maintained at a desired pressure. The outlet pressure is adjusted by deflecting the diaphragm in a direction to open the valve while permitting a section of the diaphragm connected to the valve member to remain responsive to the pressure in the chamber. An adjustment cover is provided to adjustably deflect the diaphragm and includes a catch mechanism to allow adjustment of the fluid outlet pressures and also retain the device at a desired value. An indicator arrangement may be provided to visually indicate the fluid outlet pressure.
Patent RO-126937-A0 (RO)
Title: Telescopic mast type extension device
Inventor: BUCUR IULIAN
IPC: B66F3/10
Filed: 2011-05-04
Abstract: The invention relates to a telescopic mast-type extension device which is an electromechanical assembly able to lift and fasten in a precise and repetitive position a load with a weight of maximum 100 kg from a minimal height L=300 mm up to a maximal height L= () x L, the electromechanically driven device comprises a number of "n" sections which coaxially rise from one another and it is used for positioning and supporting optoelectrical distance measuring apparatus such as laser or optical telemeters, navigation systems such as goniometers or GPS devices, for positioning and supporting video apparatuses, antennas and other equipments for height interventions. The claimed device comprises several elements: a. the base plate () made up of steel which ensures a firm fastening of the entire device, b. the driving assembly () is provided with a handle for manual actuation and for electrical actuation it is provided with a DC motor () of 24 V which develops a power of 600 W and a maximal consumption of 20 A and a double-reduction belt gear assembly, c. the external guiding system () consists of 5 concentric cylinders which slide into one another and which are guided by means of some internal and external bushes (), respectively, d. the mechanical lifting system comprises a main screw () which by rotation rises and descends the internally threaded cylindrical sections () which make a multiple helical couple, the sections () being guided by internal and external guiding bushes () which ensure the concentricity of threads during the extension thereof, e. the last section is provided with a platform interface () which plays the role of fastening and positioning the equipment to be lifted and supported.
Patent RO-129935-A0 (RO)
Title: Multilayer boards made of basalt foam with closed and open porosity
Inventor: VASIU RĂZVAN ANDREI
IPC: C04B24/24
Filed: 2014-03-14
Abstract: The invention relates to a multi-layer cellular structure board, wherein a layer has cellular structure with open pores, and is followed by one or more layers with cellular structure with closed pores, depending on the board use and loading. According to the invention, the board consists of a layer with closed pores and comprising basalt powder mixed with a foaming agent, an organic or inorganic compound, as powder, placed into a mould and of a layer with open pores consisting of basalt powder mixed with a solvent, forming a slip, which is absorbed by a spongious polymeric mass, which also comprises a pore-forming agent, these layers being heated and cooled in a controlled manner, the porosity of the layer with open pores being of up to 80%, with a controlled arrangement. As claimed by the invention, the process consists in that the basalt, as powder, with the granulation smaller than 55 μm, is mixed with a foaming agent, an organic or inorganic compound, as powder, with a granulation of 25...55 μm, and it is placed in a mould, forming a layer with closed pores, and another quantity of basalt powder mixed with a solvent in a ratio of 15...30%, as slip, is absorbed in a spongious polymeric mass, placed into the mould, over the first layer and the pore-forming agent, and then heated in a slow mode, up to 450°C, at this temperature the mixture being kept for 15...30 min, then being heated at 900...1050°C, for foaming and sintering the basalt in order to block the gas in the basalt mass, there occurring the solidification, afterwards the material being cooled up to 550°C, at a rate of 50...100°C/min. From 550°C up to the environment temperature, the cooling is carried out slowly, in an annealling mode.
Patent RO-131733-A0 (RO)
Title: Composition and process for cleaning and consolidating architectural elements of heritage buildings
Inventor: ION RODICA MARIANA
IPC: E04G23/02
Filed: 2016-11-29
Abstract: The invention relates to a composition and to a process for cleaning and consolidating deteriorated decorative elements, such as stucco works and facade elements, while reconstructing the initial appearance of these elements. According to the invention, the composition comprises: a. a quantity of 1...4 g of titanium dioxide dissolved in 100 ml of water, 50...100 ml of hydroxyapatite as suspension type I, 1...4 g of phyllosilicate mineral clay as powder with the size ranging between 0.03...0.053 μm, stirred for 60 min, resulting in a consistent glossy white paste, b. a quantity of 1...4 g of TiO, 2.5 g of dried powder of hydroxyapatite ground in a mortar up to a granulation of 30...70 nm and admixed with 1...4 g of phyllosilicate clay as powders with a granulation of 0.03...0.053 μm, homogenized by stirring, after which it is added into 50...100 ml of distilled water while stirring at 300 rpm at the room temperature, until a paste is obtained. As claimed by the invention, the process consists in mechanically de-dusting the surface to be reconditioned, with a soft brush, under low ventilation, removing the wax deposits with the seaming tool, applying, with a brush or a putty knife, a layer of 0.2 mm, by two applications, followed by drying in air for 12 hours.
Patent RO-132917-A0 (RO)
Title: Dispersing systems
Inventor: CORABIAN CLAUDIU-PAUL
IPC: B67D1/08
Filed: 2018-07-04
Abstract: The invention relates to dispersing systems incorporating containers of the tank-in-tank type, in particular multi-chamber containers, to the manufacturing of a premoulds set for said containers and also to a process of manufacturing the same. The claimed dispersing systems comprise a container which is of composite/laminate-type, consisting of an outer unit (320) and at least one inner unit (340, 360), in which container in which at least two individual storage compartments (310) result from the moulding of a double-walled partitioning system (361), inside the container, where the double-walled partitioning system (361) separates vertically or substantially vertically said at least two individual storage compartments (310) and where the system (361) is formed by the exfoliation of the external structure of the container in at least one region (306, 305) with distinct functional role and by displacing, in a specific area, of at least one so-detached inner surface, this indicated surface belonging to one of at least one inner unit (360). The claimed process for manufacturing the container involves in a first stage the provision of a container of the tank-in-tank type, in the stage at which it is at the completion of the blow-molding process, the configuration of at least one incipient side compartment in the opening area in the region of an upper segment of the container, the introduction of at least one pressurized fluid into the said at least one incipient side compartment, action which determines the exfoliation of the external structure of the container in certain regions (306, 305) with distinct functional role, the displacement of the inner exfoliated surfaces, belonging to one of said at least one unit (360), in specific areas inside the container and, consequently, the creation, inside the container, of a storage system (361) and storage compartments (310).
Patent RO-137266-A0 (RO)
Title: Dentistry teaching model
Inventor: TOFAN CONSTANTIN CLAUDIU
IPC: G09B23/28
Filed: 2022-09-22
Abstract: The invention relates to a teaching model intended to be used by persons teaching or studying dentistry or dental technology. According to the invention, the model consists of two arches (1 and 2) of the upper and lower part of the oral cavity respectively, having printed on the external and internal surface the total length of the teeth, the length and width of the vestibular surfaces, the diameter of the teeth, the maximum convexities, the active cusps, the centric contacts, the inclination of the teeth, the onset of calcification, the completion of the crown, the number of roots and root canals, the palatal rugae and incisive papilla, the hard and soft palate and the order of cusps, the arches (1 and 2) being connected by a movable joint (3) consisting of two supports (4 and 5) fixed behind the arches (1 and 2) of the upper and lower part, respectively, the two arches (1 and 2) having two stoppers (6) fixed on the right side.
Patent IE-910619-A1 (IE)
Title: Compacting and selecting machine for solid and ferrous or¹non-ferrous metallic refuse such as containers, cans,¹bottles and similar
IPC: B03B9/06
Filed: 1991-02-25
Abstract: A compacting and selecting machine for solid refuse such as containers and similar, comprising a combination of a loading hopper (8) provided with a detector (13) and guide (11) of objects, a crushing press (2) at the end of the said hopper, a lateral conveyor belt (22) to which the object leaving the press is directed by a lateral ejector (18), the said conveyor belt being located over a magnetic plate (24) for the retention of ferrous or similar objects, and at least two collecting bins for the selected objects, one of these bins being for non-ferrous materials and one for ferrous materials selected by the said magnetic plate, the machine cycle being carried out with the aid of auxiliary programming means.
Patent LU-82145-A1 (LU)
Inventor: DEVREUX A
IPC: C12N1/16
Filed: 1980-02-07
Abstract: A process for adjusting the amount of yeast introduced into a fermentative liquid comprises periodically taking a sample from a mass of suspended yeast maintained in movement in a closed circuit, subjecting the sample to fermentation by adding a nutrient element, and adjusting the supply of yeast to the liquid in accordance with the fermentative power of the treated yeast sample. The implementing plant comprises a container having a conical bottom containing yeast suspended in a liquid, a pipe connecting the bottom of the container to a fermentation tank, and a regulating or adjusting pump for supplying yeast from the container into the tank. A pipe for recycling the suspended yeast in the container is provided, as well as means for ensuring, during a predetermined time interval, the recycling of the suspension of yeast from the bottom of the container to the upper part thereof. Sampling means periodically extract a predetermined volume of the recycling yeast suspension and deliver it to a small fermenting vessel whereat the nutrient agent is supplied. Means are then provided for determining the fermentative power of the yeast sample and for adjusting the yeast supply of the fermentation tank in accordance therewith.
Patent MA-22957-A1 (MA)
Inventor: ALLAN BURDON
IPC: C11D3/075
Filed: 1993-08-19
Abstract: A concentrated aqueous surfactant solution comprising alkyl ether sulphate and alkaline earth metal, preferably magnesium. The composition is a stable liquid which is suitable for making into cleaning products, especially dish washing liquids. The concentrated surfactant solution can be prepared by partial neutralisation of the acid precursor with the hydroxide or oxide of the alkaline earth metal, followed by a further neutralisation with the hydroxide of an alkali metal or ammonium.
Patent MA-24899-A1 (MA)
Title: Une composition detergente
Inventor: FRANK ANDREJ KVIETOK
IPC: C11D1/86
Filed: 1998-10-09
Abstract: LA PRÉSENTE INVENTION CONCERNE DES COMPOSITIONS DÉTERGENTES COMPRENANT DES COMPOSÉS TENSIOACTIFS ANIONIQUES RAMIFIÉS PAR DES CHAiNES MOYENNES ET DES TENSIOACTIFS ANIONIQUES SUPPLÉMENTAIRES DE TYPE SULFATE ET SULFONATE.  LES COMPOSITIONS SONT PARTICULIèREMENT UTILES EN TANT QUE COMPOSITIONS TÉTERGENTES SOLIDES POUR LE LAVAGE DU LINGE.
Patent MA-24716-A1 (MA)
Title: Lavabo mobile a robinet assiste par infrarouge
Inventor: HALOUM MOHAMED
IPC: A47K1/00
Filed: 1998-12-09
Abstract: LAVABOT MOBILE SUR ROULETTES QUI PEUT SERVIRE L'EAU TIèDE ET LE SAVON LIQUIDE SANS OUVRIRE LES ROBINETS, PAR UNE SIMPLE INTERUPTIONS DES FAISCEAUX INFRAROUGE R1 ET R2 ON PEUT NOUS SERVIRE SANS DÉPLACEMENT VERS LES TOILETTES ET SANS EFFORT.
Patent MA-27002-A1 (MA)
Title: Amides d'acide anthranilique, procede pour les preparer, leur utilisation comme antiarythmiques et preparations pharmaceutiques les contenant
Inventor: BRENDEL JOACHIM
IPC: C07D307/14
Filed: 2003-09-16
Abstract: Amides d'acide anthranilique, procédé pour les préparer, leur utilisation comme antiarythmiques et préparations pharmaceutiques les contenant L'invention concerne des amides d'acides anthraniliques, un procédé pour leur production, leur utilisation comme médicament, et des préparations pharmaceutiques contenant ces amides d'acide anthranilique. Les amides d'acide anthranilique consistent en composés de formule I oé R1 à R7 ont les significations citées dans les revendications, agissent sur le canal potassique Kv1.5 et inhibent un courant de potassium décrit comme étant un "ultra-rapidly activating delayed rectifier" dans l'oreillette cardiaque humaine. Les composés sont donc particulièrement appropriés comme nouvelles substances actives antiarythmiques, en particulier pour traiter et prévenir les arythmies auriculaires, par exemple la fibrillation auriculaire AF ou le battement auriculaire.
Patent MA-44179-A1 (MA)
Title: Compositions comprenant un virus adeno-associe exprimant des constructions a double anticorps et leurs utilisations
Inventor: WILSON JAMES
IPC: C12N15/861
Filed: 2015-05-13
Abstract: La présente invention concerne un virus adéno-associé recombiné (aav) comprenant un capside d'aav et un acide nucléique hétérologue inclus dans celui-ci qui exprime deux constructions d'anticorps fonctionnels dans une cellule. L'invention concerne également des anticorps comprenant une chaîne lourde et une chaîne légère d'un anticorps hétérologue. Dans un mode de réalisation, les anticorps sont co-exprimés à partir d'un vecteur contenant : une première cassette d'expression qui code pour au moins un premier cadre ouvert de lecture (orf) pour une première immunoglobuline sous le contrôle de séquences régulatrices de contrôle qui dirigent son expression ; et une seconde cassette d'expression qui comprend un deuxième orf, un lieur, et un troisième orf sous le contrôle de séquences régulatrices de contrôle qui dirigent son expression, le deuxième et le troisième orf codant pour une deuxième et une troisième construction d'immunoglobuline. Dans un mode de réalisation, le vecteur exprimant conjointement ces deux constructions d'anticorps est un aav, dans lequel les séquences répétées inversées terminales en 5' et 3' encadrent les cassettes d'expression et les séquences régulatrices
Patent MA-47004-A1 (MA)
Title: Procédé d'élimination des métaux lourds de l'acide phosphorique
Inventor: HANNACHE HASSAN
IPC: C01B25/238
Filed: 2019-09-18
Abstract: Procédé d’élimination des métaux lourds d’une solution ou de bouillies d’acide phosphorique en ajoutant des sulfures alcalins qui, en présence de la matière organique, conduisent à la formation de complexes organométalliques. Ces complexes précipitent aisément dans l’acide phosphorique et s’éliminent par simple filtration, décantation ou raclage mécanique.
Patent MA-47657-A1 (MA)
Title: Compositions et méthodes pour l'internalisation d'enzymes
Inventor: KYRATSOUS CHRISTOS
IPC: C12N9/34
Filed: 2018-06-06
Abstract: L'invention concerne des compositions et des méthodes de traitement de maladies caractérisées par une déficience enzymatique. Des protéines thérapeutiques multidomaines contenant un domaine de liaison à l'effecteur d'internalisation et une activité enzymatique lysosomale de remplacement sont décrits. Les complexes thérapeutiques multidomaines sont capables de pénétrer dans des cellules, de se séparer du lysosome, et de fournir l'activité enzymatique de remplacement au lysosome.
Patent MA-59997-A1 (MA)
Title: Procédé de préparation de solutions de sulfate métallique de qualité de batterie
Inventor: LANTTO CORNELIA
IPC: C01G51/10
Filed: 2021-09-07
Abstract: Des solutions de sulfate métallique de qualité de batterie peuvent être préparées directement à partir d'objets métalliques produits par électrolyse, tels que des plaques de cathode, lorsque ceux-ci sont soumis à une solution aqueuse de lixiviation comprenant au moins un agent de lixiviation acide et un agent oxydant liquide dans un procédé continu à température élevée et avec un mélange vigoureux. L'invention concerne également un agencement de lixiviation comprenant une colonne de lixiviation ou un récipient de réaction.
Patent UY-23614-A1 (UY)
Title: Perfeccionamiento de accion reciproca
IPC: H01F7/00
Filed: 1993-07-12
Abstract: Perfeccionamiento de acción reciproca caracterizado por generar movimientos lineales, rotatorios, etc. por interacción de cuerpos magnéticos cuyas masas mecánicas aumentan en alguna o algunas de sus magnitudes y campos magnéticos del mismo signo o fuerza enfrentados. Dicha interacción puede, a voluntad, actuar como motor o como freno sin rozamiento mecánico en las realizaciones prácticas. Actúa como motor en los casos que el electroimán se desactive en los momentos en que las zonas de mauor masa mecánica enfrentan los polos de los imanes; por inercia continúa el movimiento de los cuerpos magnéticos y de inmediato vuelven a activarse los electroimanes. Cuando los cuerpos magnéticos enfrentan sus zonas de mauor masa mecánica, los electroimanes activados frenan los movimientos de los cuerpos magnéticos. Con la adecuada y conveniente utilización de imanes permanentes es posible ahorrar importantes costos de energía.
Patent UY-24547-A1 (UY)
Title: Procedimiento para preparar derivados de quinolina
Inventor: DR CARLO FARINA
IPC: C07D221/02
Filed: 1997-05-07
Abstract: La presente invención se refiere a un procedimiento para la preparación de un compuesto de fórmula (I) (figura 1) o una sal del mismo, o un solvato del mismo, en la que R2 es un resto -O-(CH2)n-X en el que X es, entre otras posibilidades, un grupo heterocíclico de un solo anillo o de anillos condensados unidos a C, estando cualquiera de los anillos saturado o no saturado y consistiendo cada anillo de 5 a 6 átomos, comprendiendo dichos átomos del anillo 1 0 2 átomos de nitrógeno y, opcionalmente, 1 o 2 hetero-átomos seleccionados de O o N y en el cual uno o dos átomos del anillo estan opcionalmente sustituidos. Como ejemplo no limitante: (S)-N-(alfa-etilbencil)-3-hidroxi-2-fenilquinoleína-4-carboxamida. Se describe también un procedimiento para preparar el compueto.
Patent UY-26883-A1 (UY)
Title: Combinación terapéutica
Inventor: SHEAR CHARLES LESTER
IPC: A61P9/10
Filed: 2001-08-14
Abstract: La presente invención se refiere a combinaciones farmaceúticas de un inhididor de CETP y atorvastatina o sus metabolitos hidroxílicos o una de sus sales farmacéuticamente aceptables, métodos para utilizar tales combinaciones y kits que contienen tales combinaciones para el tratamiento de aterosclerosis, angina de pecho, niveles elevados de colesterol y niveles bajos de HDL y para el tratamiento del riesgo cardíaco.
Patent UY-27064-A1 (UY)
Title: Composiciones duras de repostería con sabor modificado que contienen ingredientes funcionales
Inventor: JEAN-MARIE JORDAN
Filed: 2001-12-07
Abstract: Composiciones de repostería mejoradas para golosina cocida dura y de goma dura que tienen una reducción sustancial de las sensaciones organolépticas desagradables en la cavidad oral relacionadas con la liberación de ingredientes funcionales de la confitura. La composición de golosina comprende una base de repostería, un ingrediente funcional que es botánico, o un mineral o una sal mineral que tienen una desagradable sensación bucal, y de un 0,5 % a un 5,0 % en peso de la composición de uno o más aceites vegetales parcialmente hidrogenados o grasas saturadas, eficaz para eliminar la sensación bucal desagradable del ingrediente funcional.
Patent UY-27566-A1 (UY)
Title: Combinación farmacéutica.
Inventor: YEADON MICHAEL
IPC: C07H19/16
Filed: 2002-12-05
Abstract: La presente invención se refiere a una combinación que comprende (a) un agonista del receptor de adenosina A2a como se define en la presente memoria y (b) un agonista del receptor B2-adrenérgico, para la administración simultánea, secuencial o por separado por vía inhalada en el tratamiento de una enfermedad obstructiva de las vías respiratorias u otra enfermedad inflamatoria.
Patent UY-29103-A1 (UY)
Title: (hetero)ciclilcarboxamidas para combatir hongos daninos
Inventor: GROTE DR THOMAS
IPC: A61K31/4155
Filed: 2005-09-06
Abstract: LA INVENCIÓN SE REFIERE AL USO DE (HETERO)CICLILCARBOXAMIDAS DE LA FORMULA i EN DONDE LAS VARIABLES, SUSTITUYENTES Y PARAMETROS SON TALES COMO SE DEFINIERON Y ESPECIFICARON EN LA MEMORIA DESCRIPTIVA; Y AL USO DE SALES DERIVADAS AGROCULTURALMENTE UTILES PARA CONTROLAR HONGOS FITOPATOGENOS. LA INVENCIÓN TAMBIÉN SE REFIERE A NUEVOS COMPUESTOS DE FORMULA i Y A COMPOSICIONES QUE LOS CONTIENEN.