baber/WOPTO huggingface dataset:
Patent PT-871439-E (PT)
Inventor: SALVINO JOSEPH M
IPC: A61P31/00
Filed: 1997-01-02
Abstract: This invention is directed to compounds of formula I: wherein the variables are as described herein. Compounds within the scope of the present invention possess useful properties, more particularly pharmaceutical properties. They are especially useful for inhibiting the production or physiological effects of TNF in the treatment of a patient suffering from a disease state associated with a physiologically detrimental excess of tumor necrosis factor (TNF). Compounds within the scope of the present invention also inhibit cyclic AMP phosphodiesterase, and are useful in treating a disease state associated with pathological conditions that are modulated by inhibiting cyclic AMP phosphodiesterase, such disease states including inflammatory and autoimmune diseases, in particular type IV cyclic AMP phosphodiesterase. Compounds within the scope of the present invention may also inhibit an MMP, and are useful in treating a disease state associated with pathological conditions that are modulated by inhibiting MMPs, such disease states involve tissue breakdown and those associated with a physiologically detrimental excess of TNF. The present invention is therefore also directed to the pharmaceutical use of the compounds, pharmaceutical compositions containing the compounds, intermediates leading thereto and methods for the preparation of the compounds and their intermediates.
Patent PT-883972-E (PT)
Inventor: KIRJAVAINEN KARI JOHANNES
IPC: H04R19/01
Filed: 1997-02-26
Abstract: The invention relates to an acoustic element and method for sound processing. The acoustic element (1) is made of a porous stator plate (2) which is either electrically conductive or plated on at least one of its surfaces to be conductive. A moving diaphragm (3, 3a, 3b) has been attached to the stator plate (2). To measure as well as produce sound pressure and particle velocity, the equipment comprises two pairs of aforementioned acoustic elements (1). Elements serving as sensors control elements serving as actuators to attenuate and absorb sound.
Patent PT-956033-E (PT)
Inventor: RINEMART KENNETH L
IPC: A61P37/06
Filed: 1997-10-24
Abstract: Disclosed is a synthetic method for the preparation of analogs of Didemnin A (1), particularly the Amino-Hip analog of Didemnin A, also known as "AipDidemnin A" (8). These compounds have the following structures:
Patent PT-948436-E (PT)
Inventor: CHADWICK BARRY W
IPC: B43K7/10
Filed: 1997-10-21
Abstract: A writing instrument is disclosed having a barrel defining an internal passage including an ink reservoir. A venting mechanism is positioned at least partially within the internal passage of the barrel adjacent an anterior end portion thereof. The venting mechanism includes an elongated body defining an axial bore therethrough in communication with the ink reservoir, and a plurality of spaced apart fins peripherally surrounding the elongated body and defining a plurality of annular channels between the fins. Each of the fins defines a groove thereon to interconnect the annular channels. The writing instrument further includes a point support member supporting a writing point and positioned adjacent an anterior end portion of the venting mechanism and defining an axial bore aligned with the axial bore of the venting mechanism. A first ink supply rod is disposed within the axial bore of the venting mechanism and has a posterior end portion in communication with the ink reservoir to convey ink from the ink reservoir to an anterior portion of the venting mechanism. A second supply rod conveys ink from a posterior end portion disposed within the bore in the venting mechanism and contacting the first supply rod to an anterior end portion disposed within the bore of the point support member, to the writing point. A circuitous air path is provided to vent the ink reservoir at the posterior end portion to the writing tip portion.
Patent PT-985042-E (PT)
Title: Protease enzymes for tough cleaning and/or spot and film reduction and compositions incorporating same
Inventor: NMN SAROJ RAI
IPC: C12N15/57
Filed: 1998-06-02
Abstract: The present relates to cleaning compositions comprising a protease enzyme which is a carbonyl variant having an amino acid sequence not found in nature, which is derived by replacement of a plurality of amino acid residues of a precursor carbonyl ydrolase with different amino acids.
Patent PT-1019022-E (PT)
Inventor: WEERS JEFFRY GREG
IPC: A61K9/22
Filed: 1998-09-29
Abstract: Stabilized dispersions are provided for the delivery of a bioactive agent to the respiratory tract of a patient. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that typically comprises a hydrofluoroalkane propellant. As density variations between the suspended particles and suspension medium are minimized and attractive forces between microstructures are attenuated, the disclosed dispersions are particularly resistant to degradation, such as, by settling or flocculation. In particularly preferred embodiments, the stabilized dispersions may be administered to the lung of a patient using a metered dose inhaler.
Patent PT-1047377-E (PT)
Inventor: LANG GERARD
IPC: C09B67/10
Filed: 1998-12-18
Abstract: The invention concerns a ready-to-use composition for dyeing human keratinous fibers and more particularly human hair, comprising in support suitable for dyeing keratinous fibers: (a) at least an enzyme such as laccase; (b) at least a cationic substantive or particular amphoteric polymer; (c) at least an oxidation coloring agent, as well as the dyeing methods using said composition.
Patent PT-947209-E (PT)
Inventor: BOHDAN PAVLU
IPC: A61M5/24
Filed: 1994-10-10
Abstract: An injection cartridge (1) of the dual-chamber type has a bypass connection (12) between its two chambers (9, 10) which is arranged such that the interior wall of the cartridge is modified in a predetermined area in such a way that the movable wall (11) between the two chambers does not seal completely against the interior wall in said area. According to the invention, the modification of said wall is arranged as a plurality of lands and grooves (12) which have a direction that is inclined in relation to the longitudinal axis of the cartridge barrel. <IMAGE>
Patent CA-2233265-F (CA)
Inventor: COOKE T DEREK V
IPC: A61F2/38
Filed: 1998-03-26
Granted: 1998-10-04
Abstract: A knee prosthesis, includes a femoral element, a tibial element and at least one bearing element between the femoral and tibial components. The femoral component has medial and lateral condylar elements that extend posteriorly about 160°.
Patent SG-173294-G (SG)
Title: Fibers capable of spontaneously transporting fluids
Inventor: PHILLIPS BOBBY MAL
IPC: A61F13/15
Filed: 1994-12-06
Abstract: Disclosed are fibers that are capable of spontaneously transporting certain fluids, for example aqueous fluids, such as water, on their surfaces. The fibers, especially in the form of tow, can be incorporated into absorbant articles, such as diapers, in order to transport fluids to more effectively utilize the absorbant portion of the article.
Patent IE-40566-L (IE)
Title: Ó-galactosidase
IPC: A23L11/30
Filed: 1975-01-17
Abstract: A process for the production of alpha -galactosidase by culturing the mold Penicillium duponti in an aqueous medium containing at least one sugar with at least one alpha D-galactopyranosyl bond and collecting the mycelium thus obtained.
[US3966555A]
Patent IE-860181-L (IE)
Title: Process for controlling the formation of sheet materials¹such as pipes
IPC: D21F1/00
Filed: 1986-01-21
Abstract: The invention relates to a process for controlling the formation of sheet material such as paper. An example of the operation of the invention involves a slurry of fibrous paper flowing through a slot (16) the size of which is governed by a slice lip (14) (thickness regulating member) itself controlled by actuator rods (51). The movements of the actuators to control the thickness of the paper formed are based upon physical characteristics of the slice lip (14) and of the actuators (51).
[EP0189311A1]
Patent IE-790292-L (IE)
Title: Dehydrocyclicimino acids.
IPC: A61K31/40
Filed: 1979-02-14
Abstract: New compounds which have the general formula <IMAGE> ARE USEFUL AS HYPOTENSIVE AGENTS.
[US4129566A]
Patent IE-35172-L (IE)
Title: Hydrostatic extrusion press.
IPC: B21C23/00
Filed: 1971-04-27
Abstract: A press for hydrostatic extrusion includes a press stand and a high pressure cylinder displaceable in the stand. A punch is mounted for movement into the high pressure cylinder to produce the extrusion pressure therein. The billet and die are positioned by a manipulating arrangement between the open end of the high pressure cylinder and a die support, and the cylinder is moved over the billet and die. Pressure fluid is then introduced through the die support and die into the pressure chamber, flow of the fluid out of the chamber being prevented by a valve arrangement or by seating of the billet against the die. The punch is then advanced into the pressure cylinder to produce extrusion.
[US3709014A]
Patent IE-800608-L (IE)
Title: Pyrazinoyl guanidines.
IPC: C07D241/32
Filed: 1980-03-25
Abstract: The case involves novel heterocyclic substituted pyrazinoylguanidines and a process for preparing same. The heterocyclic pyrazinoylguanidines are eukalemic agents possessing diuretic and natriuretic properties.
Patent IE-44286-L (IE)
Title: Conveyor assembly
IPC: B65G15/24
Filed: 1976-03-29
Abstract: A conveyor assembly comprises a main conveyor and a boom conveyor. A mounting is pivotally connected at the discharge end of said main conveyor for movement about a transverse axis relative to said main conveyor, said mounting having a rotatable support on which the boom conveyor is mounted for pivotal movement laterally. A linkage retains said mounting in a horizontal position extended outwardly beyond said discharge end with said rotatable support upright. The support has an attachment device at its upper end providing for pivotal connection about a transverse axis of said boom conveyor for movement thereof in a vertical plane, the boom conveyor being supported by a length-adjustable tie from said mounting. The linkage comprises a series of interconnected pivotal links between said mounting and said main conveyor to provide for synchronized adjustment of the mounting to maintain the support upright on alteration of the inclination of said main conveyor.
[US4058198A]
Patent IE-821023-L (IE)
Title: Specimen slide for occult blood testing
IPC: G01N33/52
Filed: 1982-04-30
Abstract: An improved specimen test slide having a front panel and a rear panel. The front panel has one or more openings. Sheet means carrying a test reagent underlie each of these openings for reception of a specimen. A hinged cover overlies the openings. The rear panel has flap means opposite said openings which is pivotable to expose the underside of the sheet to permit application of a developing solution. The underside of the sheet which faces the rear panel also has a control area positioned on a portion thereof at some distance from the portions of the sheet underlying the openings of the front panel. The control area contains positive and negative monitors.
Patent IE-811037-L (IE)
Title: Taurine derivatives
IPC: C07D209/48
Filed: 1981-05-11
Abstract: PCT No. PCT/FI81/00037 Sec. 371 Date Jan. 11, 1982 Sec. 102(e) Date Jan. 11, 1982 PCT Filed May 22, 1981 PCT Pub. No. WO81/03492 PCT Pub. Date Dec. 10, 1981.The invention relates to taurine derivatives with the chemical structure: <IMAGE> where R1=H R2=a lower alkyl group with up to 4 carbonatoms or an acetyl group or where <IMAGE> These compounds were found in pharmacological studies to have qualities which make them useful as drugs.
[US4556673A]
Patent IE-801289-L (IE)
Title: Cephalosporins.
IPC: C07D501/20
Filed: 1980-06-20
Abstract: Cephalosporins of the formula   <IMAGE>   wherein A is phenyl, 4-hydroxyphenyl, cyclohexyl, cyclohexene-1-yl, cyclohexa-1,4-diene-1-yl, 2-thienyl, 3-thienyl, 2-furyl, 3-furyl or 3,4-disubstituted phenyl, where the substituents, which may be identical to or different from each other, are each chlorine, hydroxyl or methoxy; Y is hydrogen or methoxy; D is hydrogen, hydroxyl, acetoxy, aminocarbonyloxy, pyridinium, aminocarbonyl-pyridinium or the group S-Het, where Het is 1-methyl-tetrazol-5-yl, tetrazol-5-yl, 3-methyl-1,2,4-thiadiazol-5-yl,1,2,4-thiadiazol-5-yl, 1,3,4-thiadiazol-5-yl, 2-methyl-1,3,4-thiadiazol-5-yl, 2-methylamino-1,3,4-thiadiazol-5-yl, 2-dimethylamino-1,3,4-thiadiazol-5-yl, 2-formylamino-1,3,4-thiadiazol-5-yl, 2-acetylamino-1,3,4-thiadiazol-5-yl, 2-methyl-1,3,4-oxadiazol-5-yl, 1,2,3-triazol-4-yl or 1,2,4-triazol-3-yl; R is hydrogen, methyl, cyclopropyl, hydroxyl, methoxy, ethoxy, mercapto, morpholino, thiomorpholino, thiomorpholino-S-oxide, thiomorpholino-S,S-dioxide, <IMAGE>  +TR  <IMAGE>  E is hydrogen or a protective group which is easily removable in vitro or in vivo; and non-toxic, pharmacologically acceptable salts thereof.
Patent IE-881373-L (IE)
Title: Expression of foreign genes in drosophila cells
IPC: C12N9/48
Filed: 1988-05-06
Abstract: The present invention relates to the development of a selection system to co-introduce and express foreign genes in Drosophila cells particularly tissue plasminogen activator (tPA).
Patent IE-36018-L (IE)
Title: Explosive compositions
IPC: C06B47/14
Filed: 1971-12-07
Abstract: 1314460 Explosive compositions ICI AUSTRALIA Ltd 3 Dec 1971 [16 Dec 1970] 56206/71 Heading C1D [Also in Division C3] A slurry or plastic explosive composition comprises an inorganic nitrate, chlorate, or perchlorate, water, a fuel, and, as a sensitizing agent, water-insoluble particles encapsulating gas in the interior of each particle and comprising additional fuel material which may be present in the hollow interior of the particles, incorporated with the material forming the particles, or on the exterior of the particles. Some oxygen-releasing salt may also be included in the sensitizing agent. Polymeric materials for the sensitizing agent, oxygenreleasing salts, fuel, and other ingredients may be as described in Specification 1,314,285. Examples describe the following sensitizing agents: vesiculated polystyrene granules containing Al or Si powder in the vesicles, in the polymer, and/or on the outer surface of the granules, vesiculated methacrylate polymer containing sugar in the vesicles, retiporous melamine-formaldehyde resin particles or hollow glass spheres with Al on the outer surface, vesiculated polyester-styrene copolymer containing Al and ammonium nitrate in the vesicles, ground porous polyurethane containing Al, vesiculated polyester-styrene or polyvinylidene microspheres coated with Al, and glass balloons coated with Al or Si. Specification 1,156,596 is referred to.
[GB1314460A]
Patent IE-881908-L (IE)
Title: Diamond tool for rock drilling
IPC: B24D3/10
Filed: 1988-06-23
Abstract: A polycrystalline diamond tool comprising a diamond layer (A) is bonded to a support body (B) having a complex, non-plane geometry by means of a thin more than 3 mu m continuous layer (C) of a refractory material applied by PVD or CVD technique.
[EP0297072A2]
Patent IE-801952-L (IE)
Title: Feedback circuit
IPC: H03D1/24
Filed: 1980-09-18
Abstract: A feedback circuit for controlling the phase of a local oscillator provided with frequency adjusting means and delivering a local carrier wave for demodulating a data signal transmitted by single side band amplitude modulation, the said feedback circuit comprising at least one sign multiplier (21) producing the product of the sign of the local demodulation carrier shifted by a phase difference of pi /4 multiplied by the sign of the data signal to be demodulated, followed by a sign coincidence auto-correlator (22) which controls the said frequency adjusting means and correlates two versions of the signal delivered by the sign multiplier (21), one of the two versions being delayed relative to the other by an odd multiple of one fourth of the period of the carrier used for the amplitude modulation on transmission.
[US4349785A]
Patent IE-881992-L (IE)
Title: Process for the coating of granules
IPC: A61K9/50
Filed: 1988-06-30
Abstract: Granules containing waxy substances are coated in an apparatus with a horizontally arranged disc, rotating fast in a vertically arranged vessel, with one or more waxy substances or a mixture of one or more waxy substances, which are sprinkled in pulverulent form onto the granules which have been heated up to the softening point of the waxy substance.
Patent IE-802044-L (IE)
Title: Stitch through fabric
IPC: D04B21/14
Filed: 1980-10-01
Abstract: A stitch-bonded fabric made on a stitch-through type machine involves the application of a textile pattern design element (e.g. a single yarn end) disposed along non-rectilinear pathways, with segments extending essentially perpendicular to the longitudinal direction of the fabric. A block pattern may be formed thereby. A single system of longitudinal knitting thread wales with loops on the rear surface of the fabric and laps on the front surface, binds and secures the design element into an integrated unitary textile structure. In addition the fabric may include a layer of non- woven fibrous batting and a layer of filling yarns. The textile element 107 is applied by a unitary mechanism 101 which moves transversely of the fabric wales and includes a feed tube 107 and rotary brushes 109a, 109b which place and hold down the element in the stitch-forming zone. <IMAGE>
[GB2059467A]
Patent IE-892250-L (IE)
Title: Herbicidal compounds and compositions containing them
IPC: C07D213/34
Filed: 1989-07-12
Abstract: Herbicides of formula: <IMAGE> I in which: n=0,1, 2 f=0,1 A is chosen from the groups <IMAGE> in which: Ar is chosen from the groups <IMAGE> Ar-1 <IMAGE> Ar-2 <IMAGE> Ar-3 <IMAGE> Ar-4 B is chosen from optionally substituted C1-C10 alkyl and C3-C10 cycloalkyl groups or from the groups <IMAGE> B1 <IMAGE> B2 <IMAGE> B3 <IMAGE> B4
[US5100460A]
Patent IE-802258-L (IE)
Title: Quinazolines
IPC: C07C205/59
Filed: 1980-10-31
Abstract: 2,4-Diaminoquinazolines of the formula <IMAGE> (I) wherein Y1 is hydrogen or chloro, Y2 is OR, Y3 is hydrogen or OR such that when Y1 is hydrogen, Y3 is OR and when Y1 is chloro, Y3 is hydrogen or OR, and the pharmaceutically acceptable salts thereof; R represents an alkyl group having from one to three carbon atoms; taken separately, R1 and R2 are each hydrogen, alkyl having from one to five carbon atoms, cycloalkyl having from three to eight carbon atoms, alkenyl or alkynyl each having from three to five carbon atoms or hydroxy substituted alkyl having from two to five carbon atoms, when taken together with the nitrogen atom to which they are attached R1 and R2 form a substituted or unsubstituted heterocyclic group optionally containing an atom of oxygen, sulfur or a second atom of nitrogen as a ring member; their use as antihypertensive agents, pharmaceutical compositions containing them and intermediates for their production.
[US4287341A]
Patent IE-832283-L (IE)
Title: Bandage for animals and humans
IPC: A41D31/00
Filed: 1983-09-28
Abstract: A layer (14) of closed-cell foam polymeric material, which is partially absorbent and thermally insulating, is bonded to a thinner layer (18) of water-absorbent fabric, such as terry cloth, which is placed next to the body. An optional layer (16) may comprise woven nylon or spandex having longitudinal stretch, and protects the bandage from ambient heat. At each end fastening means (20, 22) may be attached. <IMAGE>
[GB2127697A]
Patent IE-862875-L (IE)
Title: Thick film conductor composition
IPC: C03C3/062
Filed: 1986-10-31
Abstract: Thick film conductor compositions comprising an admixture of finely divided particles of A. noble metal, noble metal alloy or mixtures thereof, and B. inorganic binder comprising a glass corresponding to the formula Bi4Si3-xGexO12, having ZnO dissolved therein, and C. A glass bleed-out inhibitor selected from pyrochlore-related oxides, metal resinates and mixtures thereof, all of A through C being dispersed in D. organic medium.
[US4636332A]
Patent IE-853152-L (IE)
Title: Composites reinforced with high strength aramid fibres
IPC: C08L101/00
Filed: 1985-12-13
Abstract: A composite comprising a matrix resin reinforced with a sliver of high modulus p-aramid fibers of which at least 10% of the fiber ends are fibrillated into at least 2 fibrils along a terminal length which is at least 5 times as long as the diameter of the unfibrillated portion of the fiber.
Patent IE-893409-L (IE)
Title: Multipurpose hinge apparatus for foldable telephones
IPC: H04M1/02
Filed: 1989-10-23
Abstract: The hinge is for a foldable telephone having a body portion and a flip element portion, the hinge being capable of maintaining the flip element portion in at least two positions of rotation relative to the body portion. A first position is parallel to a front surface plane of the body portion and a second position at an obtuse angle to the front surface plane of the body portion, the hinge comprising a first cylindrical hinge shaft rotatably coupling the flip element portion to the body portion. - First and second recesses are disposed in the wall of the first cylindrical hinge shaft, the first and second recesses having planar bottom surfaces, the plane of the planar bottom surface of the first recess intersecting the plane of the planar bottom surface of the second recess an acute angle. A first cam is disposed within the flip element portion and having at least one flat surface which contacts the planar bottom surface of the first recess when the flip element portion is in the first position and which contacts the planar bottom surface of the second recess when the flip element portion is in the second position.
Patent NO-803547-L (NO)
Inventor: STAEHLE HELMUT
IPC: C07D233/50
Filed: 1980-11-25
Abstract: Compounds of the formula   <IMAGE>   wherein R1, R2 and R3, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, methyl, trifluoromethyl, hydroxyl or amino; R4 is straight or branched alkyl of 1 to 5 carbon atoms, allyl or benzyl; R5 is methyl, ethyl or 2-dimethylamino-ethyl; and n is 0 or 1; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as bradycardiacs.
Patent NO-823733-L (NO)
Inventor: AIGNESBERGER ALOIS
IPC: C04B24/30
Filed: 1982-11-09
Abstract: The present invention provides acid group-containing, thermostable, hydrophilic condensation products of aldehydes and ketones, wherein the ketones used are symmetrical or asymmetrical ketones with acyclic aliphatic, araliphatic and/or aromatic radicals, at least one radical being non-aromatic. The present invention also provides processes for the production of these condensation products, which can be used as thickening agents, retention agents, surface-active agents, dispersion agents and/or liquefying agents, especially in aqueous systems.
Patent NO-841614-L (NO)
Inventor: MURI WERNER
IPC: F28F21/08
Filed: 1984-04-24
Abstract: A condenser comprising a condenser shell, a plurality of titanium tubes and a titanium tube plate, wherein the condenser shell at the junction with the tube plate is explosion plated with titanium and a water-tight weld is provided between the titanium plating and the tube plate.