baber/WOPTO huggingface dataset:
Patent WO-2019118771-A1 (WO)
Title: Vaccins anticancer ciblant lemd1 et leurs utilisations
Inventor: YAN JIAN
IPC: C07K14/47
Filed: 2018-12-13
Abstract: L'invention concerne des molécules d'acide nucléique comprenant une ou plusieurs séquences d'acide nucléique qui codent pour un antigène LEMDl consensus muté. L'invention concerne également des vecteurs, des compositions et des vaccins comprenant une ou plusieurs séquences d'acide nucléique qui codent pour un antigène LEMDl consensus muté. L'invention concerne en outre des procédés de traitement d'un individu atteint d'une tumeur exprimant LEMDl et des procédés de prévention d'une tumeur exprimant LEMDl. L'invention concerne également un antigène LEMDl consensus muté.
Patent WO-2019143554-A1 (WO)
Title: User assisting robot for shopping applications
Inventor: PAEPCKE STEPHANIE
IPC: G06Q30/06
Filed: 2019-01-14
Abstract: A robot system includes a holding compartment configured to transport one or more items and an electronic control unit having a processor and a non-transitory computer readable memory including a machine-readable instruction set. The robot system further includes a camera for capturing image data of an environment of the holding compartment and a robotic arm each communicatively coupled to the electronic control unit. The machine-readable instruction set causes the processor to receive image data of the environment of the holding compartment from the camera, determine a set of handling instructions for an item collected by the robotic arm, determine a location within the holding compartment for placing the item collected by the robotic arm based on the image data of the environment of the holding compartment and the set of handling instructions, and manipulate the robotic arm to place the item within the holding compartment at the determined location.
Patent WO-2019156933-A1 (WO)
Inventor: YAO YUHONG
IPC: G02B13/00
Filed: 2019-02-04
Abstract: L'invention concerne une caméra à trajet optique replié qui comprend deux éléments de repli de lumière tels que des prismes, et un système de lentilles indépendant situé entre les deux prismes, qui comporte un diaphragme d'ouverture et un empilement de lentilles. Le système de lentilles peut être déplacé sur un ou plusieurs axes indépendamment des prismes afin d'obtenir une mise au point automatique et/ou une stabilisation d'image optique pour la caméra. Les formes, les matières et les agencements des éléments lentilles de réfraction dans la pile de lentilles peuvent être sélectionnés pour capturer des images à haute résolution et de grande qualité tout en assurant une longueur focale suffisante pour s'adapter au second prisme.
Patent WO-2019165120-A1 (WO)
Title: Secure supply chain transactional management system
Inventor: NGUYEN KELLY D X
IPC: H04L9/06
Filed: 2019-02-21
Abstract: A networked computer system that manages the collection recording, and reporting of supply chain transactions within and between independent supply chain participants, including consumers. The system includes a platform controller, responsive to transaction requests from supply chain participants, that directs, subject to participant access verification, the creation of a blockchain record by a secure distributed ledger server node, where the record includes a supply chain unit unique serial number, a timestamp, transaction event data, and, optionally, private supply chain participant data. An access manager operates to perform participant access verification by securely verifying the identity of the supply chain participant making the transaction request.
Patent WO-2019173328-A1 (WO)
Title: Railway truck assembly having force-detecting load cells
Inventor: WIKE PAUL STEVEN
IPC: B61F5/00
Filed: 2019-03-05
Abstract: A force analysis system and method include a truck assembly that is configured to travel along a track having rails. The truck assembly includes a first side frame, a second side frame, a bolster extending between the first side frame and the second side frame, a first wheel set coupled to the first side frame and the second side frame, a second wheel set coupled to the first side frame and the second side frame, and one or more load cells disposed within the first side frame and/or the second side frame. The load cell(s) are configured to detect forces exerted in relation to the first side frame, the second side frame, and/or the bolster.
Patent WO-2019183622-A1 (WO)
Title: Systèmes applicateurs de champ électromagnétique pulsé à haute puissance
Inventor: KIRK MARTIN
IPC: A61N2/04
Filed: 2019-03-25
Abstract: La présente invention concerne des systèmes applicateurs de champ électromagnétique pulsé à haute puissance (PEMF). Ces appareils sont configurés pour piloter de multiples applicateurs pour délivrer simultanément des signaux PEMF haute puissance à un tissu. Les appareils peuvent en outre être configurés pour communiquer sans fil avec un serveur distant pour assurer la surveillance d'un patient, une prescription et/ou un entretien de dispositif.
Patent WO-2019195637-A1 (WO)
Title: Systems and methods for passive cooling and radiator for same
Inventor: GAN QIAOQIANG
IPC: F25B39/00
Filed: 2019-04-04
Abstract: Disclosed herein are systems and methods for passively cooling water vapor to enable efficient condensation, and methods of making such systems. A passive cooler can include a thermally conductive substrate having a first side and a second side opposite the first side, a coating disposed on at least a portion of the first side of the substrate, and a housing having one or more insulative walls. The insulative walls may define a vapor flow channel from an inlet to an outlet of the housing such that the second side of the substrate is exposed to water vapor flowing through the vapor flow channel.
Patent WO-2019209591-A1 (WO)
Title: Mask pattern generation based on fast marching method
Inventor: HE YUAN
IPC: G03F1/76
Filed: 2019-04-17
Abstract: Methods, apparatuses, and systems for determining a binary mask pattern from a pixelated mask pattern include: determining, by a processor, based on a fast marching method (FMM), arrival values for pixels of a portion of the pixelated mask pattern; determining the binary mask pattern based on the arrival values; and updating at least one of the arrival values based on a comparison between a design pattern corresponding to the pixelated mask pattern and a substrate pattern simulated based on the binary mask pattern.
Patent WO-2019204656-A1 (WO)
Title: Modular fluid valve
Inventor: LE TUAN VAN
IPC: E03D1/30
Filed: 2019-04-18
Abstract: Embodiments include a fluid valve with a modular and/or replaceable fluid control assembly configured and arranged to require maintenance over a product life of the fluid valve. The modular and/or replaceable fluid control assembly includes at least one portion including a setting or presetting configured and arranged to control fluid flow behavior in the fluid valve. The setting or presetting is useable to control fluid flow in the modular and/or replaceable fluid control assembly after an upgrade or replacement of at least a portion of the modular and/or replaceable fluid control assembly. Further, the setting or presetting enables the modular and/or replaceable fluid control assembly to retain the fluid flow behavior following one or more upgrades or replacements of one or more portions of the modular and/or replaceable fluid control assembly.
Patent WO-2019209723-A1 (WO)
Title: Characterization and sorting for particle analyzers
Inventor: TROTTER JOSEPH
IPC: G01N15/14
Filed: 2019-04-22
Abstract: Some embodiments of the methods provided herein relate to sample analysis and particle characterization methods. Some such embodiments include receiving, from a particle analyzer, measurements for a first portion of particles associated with an experiment. Some embodiments also include generating a tree representing groups of related particles based at least in part on the measurements, wherein the tree includes at least three groups. Some embodiments also include generating a measure of relatedness between a first group and a second group of the tree based at least in part on the measurements. Some embodiments also include and configuring the particle analyzer to classify a subsequent particle associated with the experiment with the first group real-time, wherein the subsequent particle is not included in the first portion of particles. Some embodiments also include sorting the subsequent particle.
Patent WO-2019227088-A1 (WO)
Title: Guide extension catheters and methods for using guide extension catheters
Inventor: FULLER JEFFREY STEVEN
IPC: A61M25/01
Filed: 2019-05-24
Abstract: A guide extension catheter (314) may include a proximal shaft (316) and a tubular distal sheath (326) including an exchange channel (335) allowing for access (e.g. side access) into the lumen. Guide extension catheters may be used in conjunction with a guide catheter and a medical device having a distal region disposed within the guide catheter and a proximal region disposed outside of the guide catheter. A portion of the proximal region of the medical device can be passed through the exchange channel and into the lumen, and the guide extension catheter can be advanced into the guide catheter over the medical device without removing the medical device from the guide catheter. The exchange channel can extend in a straight line path along the sheath, or may extend in an indirect path along the sheath.
Patent WO-2019232186-A1 (WO)
Inventor: WALLEN THOMAS A
IPC: G09F5/00
Filed: 2019-05-30
Abstract: L'invention concerne un article pliable ayant une forme stratifiée fixée de manière amovible à un ou plusieurs panneaux de l'article pliable.
Une languette ayant une partie de retenue peut s'étendre à partir d'au moins l'un du ou des panneaux de l'article pliable.
La languette peut passer à travers une ouverture dans la forme stratifiée, et la partie de retenue peut être plus large que la largeur de l'ouverture. L'élément de retenue peut être manipulé pour passer à travers l'ouverture afin de fixer de manière amovible la forme stratifiée à l'article pliable, et/ou de détacher la forme stratifiée de ce dernier.
Patent WO-2019236474-A1 (WO)
Title: Methods of use of cd24 for the prevention and treatment of leukemia relapse
Inventor: LIU YANG
IPC: C07K16/28
Filed: 2019-06-03
Abstract: The present invention relates to the use of a CD24 protein for preventing or treating relapse of a cancer in a subject. The present invention also relates to the use of a CD24 protein for reducing cancer stem cell activity.
Patent WO-2019241467-A1 (WO)
Title: Positive allosteric modulators of the muscarinic acetylcholine receptor m1
Inventor: LINDSLEY CRAIG W
IPC: A61K31/13
Filed: 2019-06-13
Abstract: Described are positive allosteric modulators of muscarinic acetylcholine receptor M 1 (mAChR M 1 ), pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating neurological disorders, psychiatric disorders, or a combination thereof.
Patent WO-2020005786-A1 (WO)
Title: Systems and methods for validating human mobile users with wireless signals
Inventor: MARINOVIC SRDJAN
IPC: H04L29/06
Filed: 2019-06-24
Abstract: Disclosed herein are embodiments of systems, methods, and products comprising an analytic server, which builds a pipeline of five classifiers to validate whether an electronic device is operated by a human user. The server monitors wireless signals detected by different electronic devices by triggering a signal scanning function on the electronic devices. Based on the wireless signals reported by different electronic devices, the server generates a set of signal clusters. The server applies the pipeline of five classifiers on the wireless signals detected by an electronic device by exploiting the signal clusters included in the wireless signals. If any of the classifiers determines the electronic device is a legitimate human device, the server validates the electronic device; otherwise, the server applies the next classifier. If after a number of classifiers, none of the classifiers validates the device usage, the server determines that the device is not operated by a human.
Patent WO-2020023624-A1 (WO)
Title: Modular structural composites for automotive applications
Inventor: BRANDLEY MARK W
IPC: B62D29/00
Filed: 2019-07-24
Abstract: A modular composite structure containing multiple individual composite structures attached together. The individual composite structures form sections of a vehicle component. The composite structures are lightweight and made of materials that can function to absorb energy or attenuate vibration or noise. The composite structures contain a core material adhered to a fiber layer and a fiber reinforcement region for improving the strength and stiffness of the modular composite structure. The modular composite structure can include multiple floor pan segments that can be attached to a central composite structure that can be a utility tunnel or housing.
Patent WO-2020068345-A1 (WO)
Title: Machine vision as input to a cmp process control algorithm
Inventor: CHERIAN BENJAMIN
IPC: B24B37/005
Filed: 2019-08-28
Abstract: During chemical mechanical polishing of a substrate, a signal value that depends on a thickness of a layer in a measurement spot on a substrate undergoing polishing is determined by a first in-situ monitoring system. An image of at least the measurement spot of the substrate is generated by a second in-situ imaging system. Machine vision processing, e.g., a convolutional neural network, is used to determine a characterizing value for the measurement spot based on the image. Then a measurement value is calculated based on both the characterizing value and the signal value.
Patent WO-2020047380-A1 (WO)
Inventor: THOMSON JAMES
IPC: A61L27/38
Filed: 2019-08-30
Abstract: Provided herein are human arterial endothelial cell-seeded polymeric vascular grafts suitable for replacing or bypassing natural blood vessels and exhibiting increased long term patency rates and reduced leukocyte adhesion relative to grafts comprising venous endothelial cells. Methods for generating the human arterial endothelial cell-seeded vascular grafts and therapeutic uses of the same are also described.
Patent WO-2020055975-A1 (WO)
Title: Anti-trem-2 agonist antibodies
Inventor: HOLTZMAN DAVID
IPC: A61K39/00
Filed: 2019-09-11
Abstract: The present disclosure encompasses anti-TREM-2 antibodies that promote TREM-2 activation and methods of using the anti-TREM-2 agonist antibodies therapeutically.
Patent WO-2020056332-A1 (WO)
Title: Dark acoustic metamaterial cell for hyperabsorption
Inventor: SWETT DWIGHT
IPC: G01V1/40
Filed: 2019-09-13
Abstract: Systems and methods for vibration attenuation, and for investigating a subsurface volume of interest from a borehole. System embodiments may include a vibration attenuation system, comprising: at least one vibration attenuator configured to dynamically isolate a vibration source, the at least one vibration attenuator comprising metamaterial defining a plurality of cells; wherein at least one cell of the plurality of cells comprises a plurality of sub-cells azimuthally arrayed about an axis of alignment, and at least one sub-cell of the plurality is defined by a solid, the at least one sub-cell including a plurality of cell segments substantially oriented in alignment with a mapping geometry comprising an inversion of a canonical tangent circles mapping. The vibration source may comprise an acoustic source. The system may have an enclosure having the acoustic source and the at least one receiver disposed therein, with the at least one acoustic attenuator is positioned between.
Patent WO-2020069451-A1 (WO)
Title: Extracteur auto-étalonné de von neumann
Inventor: MATHEW SANU
IPC: G06F7/58
Filed: 2019-09-27
Abstract: L'invention concerne un appareil à boîtier semi-conducteur pouvant comprendre, selon un mode de réalisation, une technologie destinée à mettre en place un extracteur d'entropie comprenant une fonction physiquement impossible à cloner (PUF), un générateur de nombres aléatoires vrais (TRNG), une source d'entropie couplée à la fois à la PUF et au TRNG, et un circuit servant à auto-étalonner l'extracteur d'entropie. D'autres modes de réalisation sont décrits et revendiqués.
Patent WO-2020081919-A1 (WO)
Inventor: GOSS DONALD
IPC: H05K7/14
Filed: 2019-10-18
Abstract: Un panneau de guidage comprend une construction unifiée qui comprend une fente de guidage, une structure de mise en prise, une structure d'alignement de transmission de données de puissance et des composants de décharge électrostatique.
Patent WO-2020096857-A1 (WO)
Inventor: BENAYAD-CHERIF FAYCAL
IPC: G06T3/40
Filed: 2019-10-31
Abstract: A laser marking system includes a laser, an image capture device, a marking head including electromagnetic energy deflectors and a lens, beam paths of the laser of the image capture device both passing through the lens, and a computer system. The computer system is programmed to perform a method including generating an image calibration model at each of multiple areas across a marking field of the laser marking system, adjusting the electromagnetic energy deflectors to direct the beam path of the image capture device to multiple different locations within the marking field of the laser marking system, and capturing image tiles at each of the multiple different locations with the image capture device, wherein at each of the multiple different locations, if a location corresponds to an area at which an image calibration model was generated, correcting the image tile according to the image calibration model generated at the location.
Patent WO-2020097210-A1 (WO)
Title: Personalized treatment for cardiomyopathy and heart failure by measuring renin activity, pro-renin, pro-renin, receptor levels in blood
Inventor: REED GUY
IPC: G01N33/50
Filed: 2019-11-06
Abstract: The present invention relates to methods of using measured plasma renin activity assayed and defined as plasma renin activity (PRA), plasma renin activity concentration (PRAC), active renin concentration (ARC), plasma renin activity concentration (PRAC) and/or active plasma renin concentration (APRC), pro-renin activity, (pro)-renin receptor (PRR) levels for diagnosing, prognosing, treating and monitoring heart failure (HF) or HF-associated conditions or other conditions that cause or are caused by altered (e.g., elevated) renin activity, pro-renin levels,· PRR levels, PRC, APRC, and/or interaction of renin or pro-renin with PRR. These methods can be used for at-risk patients for personalized therapy of heart disease to reduce heart dysfunction progression, diminish HF, and prolong life. This technology stratifies patients with HF or those at risk for HF to determine the appropriate medication (agents that specifically interfere with plasma renin activity/pro-renin and/or PRR) or intervention and the appropriate dosage of medication to treat further HF progression.
Patent WO-2020102659-A1 (WO)
Title: G-to-t base editors and uses thereof
Inventor: LIU DAVID R
IPC: C12N9/22
Filed: 2019-11-15
Abstract: The present disclosure provides for base editors which satisfy a need in the art for installation of targeted transversions of guanine (G) to thymine (T), or correspondingly, transversions of adenine (A) to cytosine (C). The domains of the disclosed base editors include a nucleic acid programmable DNA binding protein and a guanine oxidase or a guanine methyltransferase. The base editors may be engineered through the use of continuous or non-continuous evolution systems. In particular, the present disclosure provides for guanine-to-thymine (or cytosine-to-adenine) base editors that can install single-base trans version mutations. In addition, methods for targeted nucleic acid editing are provided. Further provided are pharmaceutical compositions comprising, and vectors and kits useful for the generation of, guanine-to-thymine base editors. Cells containing such vectors and cells containing base editors and guide RNAs are also provided. Further provided are methods of treatment comprising administering the base editors to a subject in need thereof.
Patent WO-2020132269-A1 (WO)
Inventor: BRENNEMAN JEHROD BURNETT
IPC: C07D487/04
Filed: 2019-12-19
Abstract: La présente invention concerne des composés représentés par la formule (I) et des sels et des solvates pharmaceutiquement acceptables de ceux-ci, X 1 , X 2 , X 11 , X 12 , R 1 , R 3 , R 5 , R 5' , R 6 , et R 7  étant tels que définis dans le descriptif. La présente invention concerne également l'utilisation de composés représentés par la formule I pour inhiber une protéine USP1 et/ou traiter une maladie en réponse à l'inhibition de protéines USP1 et de l'activité USP1. Les composés selon la présente invention sont particulièrement utiles pour le traitement du cancer.
Patent WO-2020132679-A1 (WO)
Inventor: KHODAGHOLY DION
IPC: H01L51/10
Filed: 2019-12-23
Abstract: L'invention concerne un transistor électrochimique à grille d'ions interne. Dans certains modes de réalisation, le transistor électrochimique à grille d'ions interne comprend : une électrode de grille, une électrode de source et une électrode de drain ; un canal formé entre l'électrode de source et l'électrode de drain, le canal comprenant un polymère conducteur, le canal servant de réservoir d'ions mobiles chargés positivement ; et une membrane ionique entre le canal et l'électrode de grille. Dans un état désactivé, au moins un sous-ensemble des ions mobiles chargés positivement sont liés ioniquement à des ions chargés négativement du polymère conducteur et, dans un état activé, au moins un sous-ensemble des ions mobiles chargés positivement sont séparés des ions chargés négativement du polymère conducteur pour induire un courant à l'intérieur du canal, et l'état désactivé et/ou l'état activé sont actionnés par l'application d'une tension à l'électrode de grille.
Patent WO-2020167779-A1 (WO)
Inventor: LU YU
IPC: G02B6/38
Filed: 2020-02-11
Abstract: La présente invention concerne un système de fabrication ou d'assemblage de connecteurs de fibres optiques qui permet de rendre un câble à fibres optiques pré-terminé compatible avec n'importe quel nombre de styles ou types différents de connecteurs de fibres optiques ou d'adaptateurs de fibres optiques. La présente invention concerne également un connecteur de fibres optiques ayant des première et seconde pièces connectées à une interface à couplage par torsion et comprenant également un verrouillage rotatif. La présente invention concerne un connecteur de fibres optiques ayant une gaine qui se monte dans de multiples positions axiales différentes.
Patent WO-2020205207-A1 (WO)
Inventor: BELEN JORDAN CAMERON
IPC: F16L23/036
Filed: 2020-03-13
Abstract: A pipe coupling can comprise a first segment comprising a first end and a second end distal to the first end; a second segment comprising a first end and a second end distal to the first end; a first tightening element configured to draw the second end of the first segment towards the first end of the second segment; a second tightening element configured to draw the first end of the first segment towards the second end of the second segment; and a pivot clip between the second end of the first segment and the first end of the second segment, the pivot clip configured to maintain a separation distance between the second end of the first segment and the first end of the second segment.