baber/WOPTO huggingface dataset:
Patent DE-602004024536-D1 (DE)
Inventor: ZHANG YU-WEN
IPC: A61K35/00
Filed: 2004-07-07
Abstract: Hepatocyte growth factor/scatter factor (HGF/SF), acting through the Met receptor, plays an important role in most human solid tumors and inappropriate expression of this ligand-receptor pair is often associated with poor prognosis. The molecular basis for the malignant activity imparted by signaling of HGF/SF-Met in cancer cells has been attributed to its mitogenic and invasive properties. However, HGF/SF also induces angiogenesis, but the signaling mechanism has not been understood, nor has this activity been directly associated with HGF/SF-Met mediated tumorigenesis. HGF/SF induces expression in vitro of VEGF, a key agonist of tumor angiogenesis. By contrast, thrombospondin-1 (TSP-1) is a negative regulator of angiogenesis. This application discloses that, in the very same tumor cells, in addition to inducing VEGF expression, HGF/SF dramatically down regulates TSP-1 expression. TSP shut off plays an important, extrinsic role in HGF/SF-mediated tumor development, as ectopic expression of TSP-1 markedly inhibited tumor formation through the suppression of angiogenesis. While VEGF induced expression is sensitive to inhibitors of several pathways, including MAP kinase, PI3 kinase and Stat3, TSP-1 shut off by HGF/SF is prevented solely by inhibiting MAP kinase activation. Thus HGF/SF is a "switch" for turning on angiogenesis. TSP-1 is a useful antagonist to tumor angiogenesis, and therefore TSP-1 and agonist peptides and mimics, as well as inducers of TSP-1, have therapeutic value when used in conjunction with inhibitors of VEGF.
Patent DE-602004027875-D1 (DE)
Inventor: BOS GREORGIUS RUDOLPHIUS
IPC: B66C3/02
Filed: 2004-08-17
Abstract: A device for gripping and displacing material, such as roughage for animals for example, which device is provided with a gripper (2) for gripping and subsequently displacing the material, and with a collecting device (5) comprising a collecting element (6) for collecting material falling unintentionally from the gripper (2). The device is further provided with control means comprising an operating element (7) by means of which, after the material has been gripped by means of the gripper (2), the collecting element (6) is capable of being brought from an inactive position into a further position in which the collecting element (6) is able to collect material that is lost unintentionally by the gripper (2). <IMAGE>
Patent DE-602004030451-D1 (DE)
Inventor: IRIE REIKO
IPC: G01N33/68
Filed: 2004-07-15
Abstract: IgM car be obtained in the form of a pentamer by placing the genes encoding the H, L, and J chains on the same vector to transform appropriate host cells. The gene encoding the J chain may be introduced by co-transfection. When no J chain is expressed, the IgM is produced as a hexamer. The transformants obtained according to the present invention achieve a hish yield of IgM. The present invention also provides methods which enable separation and quantification of polymeric IgM.
Patent DE-602005003183-D1 (DE)
Inventor: HAZEBROUCK STEPHEN A
IPC: A61F2/46
Filed: 2005-09-21
Abstract: An orthopaedic system comprises a set of implant components (32,34,36) sized and shaped to replace a portion of a bone, a set of trial components (18) sized and shaped to replicate at least one feature of the implant components, and a set of instruments for use in preparing the bone to receive the implant components. At least one of the sets includes a first member (32) having a longitudinal axis, a second member (34) having a longitudinal axis, and a retainer (36). One of the members (34) has a male portion (70) and the other of the members (32) has surfaces which define a female portion (50). The female portion is capable of receiving the male portion to connect the first and second members together. The female portion and the male portion are sized and shaped so that the male portion can be moved into the female portion through relative movement in a direction other than longitudinal, and the retainer is movable between an unlocked position wherein relative movement between the male portion and female portion is possible and a locked position wherein relative movement between th
Patent DE-602005006097-D1 (DE)
Inventor: IJZERMAN WILLEM L
IPC: G02B30/25
Filed: 2005-01-06
Abstract: An optical path length adjuster enables electro-optical control of a physical path length between two optical elements, suitable for use in the adjustment of an optical path length within three dimensional display devices that generate a virtual image within a defined imaging volume. The adjuster varies an optical path length between an input optical path and an output optical path and includes: a first polarization switch for selecting a polarization state for an input beam on the input optical path; first and second beam splitters having at least two possible optical paths of different lengths therebetween, for passing the input beam along a selected one of said at least two possible optical paths according to the selected polarization state of the input beam and for providing an output beam of light, on said optical output path, that has traveled along the selected optical path.
Patent DE-602005007375-D1 (DE)
Inventor: KNEE MICHAEL JAMES
IPC: G06T5/00
Filed: 2005-11-25
Abstract: A method of image segmentation using graph-theory techniques, in which pixels of an image are represented by the vertices of a graph. A minimum spanning tree is generated and edges of the tree are successively removed according to a morphological property to leave a spanning forest, trees of which correspond to segments of the image. Selection of edges for removal may depend on an energy function of a tree and on the energy function of trees created by removal of that edge.
Patent DE-602005007632-D1 (DE)
Inventor: REDGRAVE CHRIS
IPC: F16D65/12
Filed: 2005-11-08
Abstract: A tone ring of a vehicle anti-lock braking system of the type that is integrated into a disc brake rotor. The tone ring has a protective layer which enables it to withstand the combination of extreme heat and harsh environmental conditions to which it is exposed during operation of the vehicle. The protective layer is applied by thermally spraying a selected one of a plurality of materials, such as a nickel-based alloy, a high-chrome stainless steel, or non-ferrous materials such as an aluminum, copper-based alloys or a ceramic, on teeth of the tone ring, and without causing the protective layer to be deposited on the rotor braking surfaces. The protective layer generally prevents the formation of oxidation and corrosion byproduct layers on the teeth, to thereby maintain sensitivity for detection of teeth movement by the anti-lock braking system sensor during operation of the system.
Patent DE-602005010317-D1 (DE)
Inventor: HARADA HIROSHI
IPC: H04B7/26
Filed: 2005-03-04
Abstract: When a base station generates an FCM, the base station detects the use rate of a transmission buffer and decides how slots of a frame of an uplink channel are structured. When the use rate of the transmission buffer is high, the base station designates the number of ACTSs to 0 so that the base station does not accept registration requests and so forth from mobile stations. When the use rate of the transmission buffer is low, the base station designates the number of ACTSs to 1. When the number of mobile stations is large as in a large convention hall, the base station generates TDMA frames each of which has only ACTSs. The base station can decide the number of ATCSs corresponding to the probability of which registration requests and so forth from mobile stations collide.
Patent DE-602005014588-D1 (DE)
Inventor: LETOMBE MATHIEU
IPC: G06V30/40
Filed: 2005-06-16
Abstract: The method involves forming a digital image of a surface of each postal item having information of address, and binarizing the digital image. Subsidiary components (CC) of the image are extracted from the digital image of the items to perform automatic recognition operation of the address by optical code recognition (OCR) and to distinguish a group of homogenous postal items. An independent claim is also included for a sorting machine of implementing a postal item processing method.
Patent DE-602005015076-D1 (DE)
Inventor: KERN THOMAS
IPC: G06F9/44
Filed: 2005-02-11
Abstract: A computer implemented method is represented for providing to a user a context menu (240) with entries representing relationships (241, 242). The relationships (241, 242) are applicable to relate objects (231, 237) selected from a set of objects. The method comprises following method steps: receiving a first identification of a first selected object (231) from the set of objects, receiving a second identification of a second selected object (237) from the set of objects, identifying object types of the selected objects in a plurality of object types, determining one or more relationship types of which one or more relationships are applicable to the selected objects by using the identified object types, and generating for the context menu an entry (241, 242) representing a relationship of the one or more relationship types, wherein the relationship is selectable by the user to be created between the selected objects (231, 237).
Patent DE-602005016392-D1 (DE)
Inventor: BARTELS STEPHEN P
IPC: A61K31/573
Filed: 2005-03-24
Abstract: Disclosed in embodiments herein is a method of treating chronic dry eye in a patient in need thereof, the method comprising topically administering to the patient Loteprednol etabonate in an ophthalmolically acceptable carrier.
Patent DE-602005019793-D1 (DE)
Inventor: CAVAREC PIERRE-EMMANUEL
IPC: E06B9/174
Filed: 2005-03-15
Abstract: A drive device for movable window covering and/or screen, awning, roller-door, roller shutter, comprising: a mechanical subset including at least one motor (44a) and an output shaft (64), wherein the subset is elastically coupled by at least a first main rotatable elastic coupling means (52a) to the output shaft and by a second main non-rotatable elastic coupling means (70) to a non-rotatable tube (58) enclosing the subset, the second main non-rotatable noise dampening coupling means surrounding the first main rotatable noise dampening coupling means.
Patent DE-602005022330-D1 (DE)
Inventor: KNOX MICHAEL
IPC: G06K19/077
Filed: 2005-09-14
Abstract: A system and method for controlling access to a wireless networking system using RFID tags is provided. The security system and method uses RFID tags to determine the location of mobile computing device. The security system and method selectively allows access to the wireless networking system based on the determined location of the mobile computing device. For example, the security system and method will permit access to the wireless networking system if the mobile computing device is determined to be in an area of permitted access. Conversely, the security system and method will deny access to the wireless networking system if the mobile computing device is determined to be not within an area of permitted access. Thus, the system and method is able to effectively control access to the wireless networking system by only permitting access to mobile devices within designated areas.
Patent DE-602005026376-D1 (DE)
Inventor: SHIBAOKA HIROSHI
IPC: D03D13/00
Filed: 2005-03-07
Abstract: The invention aims to provide a woven/knitted fabric containing a conductive fiber preferably usable especially for a diagram for a speaker, and a diaphragm for a speaker and a speaker using the woven/knitted fabric.  A woven/knitted fabric comprising a conductive fiber and a non-conductive fiber, wherein the woven/knitted fabric has a woven structure or a knitted structure of said non-conductive fiber and a continuous wiring forming a coil of the conductive fiber.
Patent DE-602006001758-D1 (DE)
Inventor: WIKAN EGIL
IPC: A01K11/00
Filed: 2006-02-03
Abstract: A method of provisionally joining livestock tag parts, where the tag parts (1a-c, 7a-c) are welded together by ultrasonic welding without added materials. The tag parts (1a-c, 7a-c) are provided with raised portions (4, 5) that ensure a predictable resistance to breaking. The tag parts (1a-c, 7a-c) are arranged to overlap and form a strip.
Patent DE-602006002027-D1 (DE)
Inventor: NORMAN BO
IPC: D21F9/00
Filed: 2006-02-27
Abstract: Dewatering arrangement adapted to use in a twin-wire dewatering section of a stock processing machine, comprising a single-ply head box (4) for supplying stock through a nozzle (8) with an inlet (11 ) fed by a tube bank (6) with tubes (7) of non-circular cross- section, a closed loop first wire (2) adapted to receive the stock from the head box (4) on its upper surface and with pressure pulse generating blades (5) mounted inside the loop, a closed loop second wire (3) adapted to be fed on top of the first wire (2), and with pressure pulse generating blades (13) mounted inside the loop, thereby pressing the stock between itself and the first wire (2). The inlet height of the headbox nozzle (8), defined as the total tube bank height minus the total upstream thickness of eventual nozzle vanes (14), is at least 150 mm. By using a larger height of the headbox nozzle it is possible to lessen the risk of formation damages and also to use a higher slice opening, without formation disturbances. This in turn also gives better potential for paper strength and formation. The arrangement is suitable to both paper and paper board machines.
Patent DE-602006002430-D1 (DE)
Inventor: PERUZZO STEFANO
IPC: B23Q7/00
Filed: 2006-06-15
Abstract: In a plant for handling metal bars (B), particularly bars for concrete reinforcement, including at least one magazine (1) for the bars, and a bar feeding unit which feeds the bars from the magazine (1) to an operating apparatus such as a bar measuring and cutting apparatus or a bar bending apparatus, a bundle of bars is deposited on a wall which is subjected to a vibratory movement, so that the bundle is disentangled and widened in order to subsequently provide for the bars to be automatically picked up and counted from the flattened bundle.
Patent DE-602006005228-D1 (DE)
Inventor: BUCK MARKUS DR
IPC: H04M9/08
Filed: 2006-04-18
Abstract: The invention is directed to a multi-channel echo compensation system, comprising two loudspeaker input channels, each loudspeaker input channel being connected to a loudspeaker for providing a loudspeaker input signal to be emanated by the loudspeaker, a microphone output channel being connected to at least one microphone for receiving a microphone output signal from the at least one microphone, wherein each microphone is configured to acquire a signal emanating from the loudspeakers, a compensation channel for each loudspeaker input channel, each compensation channel connecting a respective loudspeaker input channel and the microphone output channel, an adaptive compensation filter for each compensation channel, wherein each adaptive compensation filter is configured to filter a signal on the respective compensation channel such that a compensation output signal is provided to compensate a microphone output signal for a signal emanating from the loudspeakers, a pre-processing means for pre-processing loudspeaker input signals on the compensation channels, the pre-processing means being configured to determine a correlation value of the loudspeaker input signals for the two loudspeakers according to a pre-determined criterion and to de-activate one of the adaptive compensation filters if the determined correlation value passes a pre-determined threshold.
Patent DE-602006007207-D1 (DE)
Inventor: ANDRE JEROME
IPC: H01R13/62
Filed: 2006-12-13
Abstract: The system has a case (6) comprising lateral faces (9, 10) that connect lateral edges of an inner face (7) to lateral edges of an upper face (8). A set of connection terminals (14-16, 74) are formed at the level of the case, and a set of electric cables (20, 22, 24, 72) has ends electrically connected to the connection terminals. Two connection devices (30, 70) connecting the electrical cables to the case are integrated to the cables and are connected to the case according to a pivotal connection. An independent claim is also included for a set of electrical cables connected to an electronic system.
Patent DE-602006009043-D1 (DE)
Inventor: JOSEPH EDOUARD
IPC: B29C45/00
Filed: 2006-10-23
Abstract: A method for sealing an automotive lamp assembly comprising a first member having a tongue assembly and a second member having a groove adapted to receive the tongue assembly of the first member. The process comprises the following steps (i) in situ injection molding a silicone composition or thermoplastic composition onto the tongue assembly (20) and/or into the groove (9) 
(ii) curing the silicone composition or thermoplastic composition in place to form a gasket (21,2) which is chemically and/or physically bonded to said tongue assembly (20) and/or groove (9) and (iii) sealing the automotive assembly by mechanically engaging the first member and the second member, at least one of which has a cured in place gasket produced in accordance with steps (i) and (ii) above.
Patent DE-602006014186-D1 (DE)
Inventor: OH UHTAEK
IPC: C07K14/47
Filed: 2006-10-18
Abstract: The present invention relates to a method for producing a recombinant, spider toxin peptide and analgesic compositions containing said peptide. More specifically, the present invention relates to a method in which the gene for GsMTx4 is subcloned into a vector, so that it is linked to a secretion signal sequence of the alpha factor and under the control of methanol-inducible alcohol oxidase (AOX) promoter to construct a recombinant yeast expression plasmid. Yeast cells are transformed with this plasmid to produce the GsMTx4 peptide and analgesic compositions containing said peptide. The recombinant yeast expression system of the present invention affords a more stable method for producing GsMTx4 than its natural route. Thus the GsMTx4 peptide and its derivatives produced by the method of this invention can be used in the cure of related diseases such as heart failure as the peptide specifically inhibits mechanosensitive ion channels.
Patent DE-602006015968-D1 (DE)
Inventor: WAHREN JOHN
IPC: A61K9/52
Filed: 2006-06-02
Abstract: The present invention provides a pharmaceutical composition for the sustained release of C-peptide. The composition is in the form of a gel containing C-peptide. The gel formation is achieved by the adjustment of pH of the composition and/or by addition of divalent metal ions. The composition does not include any other gel-forming agents. Methods for producing the composition, medical uses of the composition and products containing two or more gel compositions as a combined preparation are also encompassed.
Patent DE-602006017192-D1 (DE)
Inventor: KOCH JOERN
IPC: C12Q1/68
Filed: 2006-04-10
Abstract: The present invention relates to production of oligonucleotides using rolling circle replication, wherein synthesised multimeric oligonucleotides are reduced to mononucleotides using a nicking cassette. Thus, the invention provides a method for the production of oligonucleotides, enabling efficient amplification of oligonucleotides at lengths up to at least 1000 nucleotides and in high amounts contained within a nicking cassette.
Patent DE-602006019850-D1 (DE)
Inventor: ISHIKAWA TOMOKAZU
IPC: C12N15/09
Filed: 2006-05-11
Abstract: The present invention discloses an oligonucleotide which comprises a part or the entire sequence of the nucleotide sequence depicted in SEQ ID NO: 1, 2, 3 or 4, or a part or the entire sequence of a nucleotide sequence complementary to the nucleotide sequence, wherein the oligonucleotide is capable of hybridizing with the nucleotide sequence of  Mycobacterium kansasii ; a primer and a probe for use in the detection of  Mycobacterium kansasii  comprising the oligonucleotide; and a method for detecting  Mycobacterium kansasii  using the primer and/or probe.  The method for detecting  Mycobacterium kansasii  enables the detection  of M. kansasii  more rapidly and with higher accuracy compared with a conventional bacterium identification method performed by culture examination on a bacterium. Further, the method can exclude any false positive result for the diagnosis and can also detect and diagnose  M. kansasii  with higher accuracy compared with a diagnosis method performed by PCR using a conventional primer and/or probe. Still further, the method can quantify a  M. kansasii  cell.
Patent DE-602006020270-D1 (DE)
Inventor: BAUKMANN KARL-HEINZ
IPC: D03D39/22
Filed: 2006-06-07
Abstract: In the case of a terry loom with a drive (26) for moving backrest (14) and breast beam (23) to and fro, provision is made for the drive (26) to comprise its own drive motor (31), which drives a shaft (33) which is connected to the holding elements (28, 30) of backrest (14) and breast beam (23) by means of transmission elements (37, 38).
Patent DE-602006020792-D1 (DE)
Inventor: CHIDA KAMEL
IPC: B65D83/00
Filed: 2006-11-22
Abstract: The present invention is a food packaging system that includes a lifting basket (10) positioned within the food holding portion of the container. The lifting basket (10) forms a protective cage about the food product that allows a user to remove the food product in a sanitary manner without damage. The lifting basket (10) generally includes a base (12) that allows for drainage, and a clam shell style cage (15) that allows for easy access to the food product. A foldable handle (14) is attached to the top of the cage. With the container lid in place, the foldable handle is positioned within the container.
Patent DE-602006020980-D1 (DE)
Inventor: PETERSEN ANDERS ERIK
IPC: H01M10/36
Filed: 2006-01-12
Abstract: A rechargeable battery is provided comprising a flexible elongate electron conductive core surrounded by a first electrochemically active layer, and a second electrochemically active layer, separated by a separation layer and where an electron conducting element contacts the outer surface of the second electrochemically active layer, whereby at least one of the two electrochemically active layers and the separation layer are comprised of thin-film layers. Further a hearing aid is provided wherein a battery comprising thin film layers is provided. Such a battery may be curled or wound to accommodate an irregular space inside the hearing aid.
Patent DE-602006021637-D1 (DE)
Inventor: NEERGAARD JESPER
IPC: A23G4/12
Filed: 2006-06-16
Abstract: A chewing gum comprising at least one biodegradable polymer, sweetener in an amount from about 0.5% to about 95% of said chewing gum, one or more flavoring agents, filler in an amount from about 0 to 50% by weight of said chewing gum, further chewing gum ingredients and at least one enzyme, wherein said at least one enzyme is comprised in a hydrophobic enzyme formulation. According to the invention, it has been established that an enzymatically activated degradation may by obtained when applying a hydrophobic enzyme formulation even though the hydrophobic enzyme formulation, e.g. when applying a dispersion of substantially hydrophilic enzymes in a hydrophobic medium such as oil, might be suspected to have a negative influence on the functionality of the enzymes at the active sites of the applied enzyme.
Patent DE-602007010360-D1 (DE)
Inventor: ALCARAZ ASENSIO ANTONIO
IPC: G01N33/574
Filed: 2007-06-05
Abstract: The present invention relates to an  in vitro  non-invasive bladder cancer diagnosis and/or prognosis method based on the detection and quantification in bladder fluids of the gene expression of certain genes and/or combinations thereof acting as genetic markers of said disease. A bladder cancer diagnosis and/or prognosis kit based on the use of a set of probes suitable for the detection and quantification of the expression pattern of said genes is also contemplated.
Patent DE-602007012463-D1 (DE)
Inventor: BUTLER MICHAEL FRANCIS
IPC: A61K33/10
Filed: 2007-12-04
Abstract: An Oral care product is provided which includes a mesoporous calcium silicate biomaterial (MCSB) dispersed in a polymeric material matrix. MCSB is an insoluble composite material of calcium oxide-silica.