baber/WOPTO huggingface dataset:
Patent AU-2012202807-C1 (AU)
Title: Compositions comprising solid particles entrapped in collapsed polymeric microspheres, and methods of making the same
Inventor: SOJKA MILAN F
IPC: A61K8/72
Filed: 2012-05-14
Granted: 2013-01-17
Abstract: The present invention relates to topical compositions containing solid particles that are stabilized via entrapment by microspheres. Each of the microspheres contains a collapsed 5 polymeric shell that has entrapped therein one or more solid particles. The solid particles are preferably formed of zinc oxide or titanium dioxide or both, which can readily be used either alone or in combination with other sunscreen agents to form sunscreen compositions of broader UV protection spectrum and enhanced photostability.
Patent AU-2016280717-C1 (AU)
Title: Heterocyclic inhibitors of ERK1 and ERK2 and their use in the treatment of cancer
Inventor: VENKATESAN ARANAPAKAM M
IPC: C07D405/14
Filed: 2016-06-15
Granted: 2021-05-13
Abstract: The present application provides novel heterocyclic compounds and pharmaceutically acceptable salts thereof. Also provided are methods for preparing these compounds. These compounds are useful for inhibiting ERKl/2. By administering to a patient in need a therapeutically effective amount of one or more of the compounds of formula (I), wherein X, Y, Z, J, M, and R1 to R8 are defined herein, these compounds are effective in treating conditions associated with dysregulation of the RAS/RAF/MEK/ERK pathway. A variety of conditions can be treated using these compounds and include diseases which are characterized by abnormal cellular proliferation. In one embodiment, the disease is cancer.
Patent AU-2016341520-C1 (AU)
Title: Benzolactam compounds as protein kinase inhibitors
Inventor: BERDINI VALERIO
IPC: C07D471/04
Filed: 2016-10-20
Granted: 2021-07-22
Abstract: The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof. The compounds are inhibitors of ERK 1/2 kinases and will be useful in the treatment of ERKl/2-mediated conditions. The compounds are therefore useful in therapy, in particular in the treatment of cancer.
Patent AU-2016356684-C1 (AU)
Title: Bacteria engineered to reduce hyperphenylalaninemia
Inventor: FALB DEAN
IPC: C12N9/88
Filed: 2016-11-16
Granted: 2022-11-10
Abstract: Genetically engineered bacteria, pharmaceutical compositions thereof, and methods of modulating and treating diseases associated with hyperphenylalaninemia are disclosed.
Patent AU-2017432809-C1 (AU)
Title: Pillars as stops for precise chip-to-chip separation
Inventor: LUCERO ERIK ANTHONY
IPC: G06N99/00
Filed: 2017-09-19
Granted: 2021-08-12
Abstract: A stacked device including a first substrate that includes a quantum information processing device, a second substrate bonded to the first substrate, and multiple bump bonds and at least one pillar between the first substrate and the second substrate. Each bump bond of the multiple bump bonds provides an electrical connection between the first substrate and the second substrate. At least one pillar defines a separation distance between a first surface of the first substrate and a first surface of the second substrate. A cross-sectional area of each pillar is greater than a cross-sectional area of each bump bond of the multiple bump bonds, where the cross-sectional area of each pillar and of each bump bond is defined along a plane parallel to the first surface of the first substrate or to the first surface of the second substrate.
Patent RU-2185519-C1 (RU)
Title: Engine emergency shutdown mechanism
Inventor: MOSKALEV V S
IPC: F02D17/04
Filed: 2000-11-24
Granted: 2002-07-20
Abstract: FIELD: mechanical engineering; internal combustion engines. SUBSTANCE: invention relates to control systems of internal combustion engines. Proposed emergency shutdown mechanism has housing, head coupled with lever of high-pressure fuel injection pump drive, lock, balls, spring and electromagnet. Fuel system includes additionally a device with housing and spring-loaded spool coupled hydraulically with oil and fuel systems and coupled mechanically with electromagnetic which is electrically coupled with tank electric circuit through switch. EFFECT: simplified design of device, improved reliability, increased service life and efficiency of engine. 2 dwg
Patent RU-2187738-C1 (RU)
Inventor: SOKOLOV O I
IPC: F16L33/08
Filed: 2000-12-06
Granted: 2002-08-20
Abstract: Изобретение относится к механике, более конкретно, к деталям машин и может быть использовано в конструкции червячных хомутов для зажима гибких шлангов. Возможно использование изобретения в конструкции червячных хомутов для повышения надежности герметизации соединения шланга с патрубком при его внешнем диаметре более 50 мм. В корпусе установлен червячный винт. Лента одним своим концом закреплена в корпусе, а другим концом взаимодействует с винтом. На внутренней поверхности ленты в районе корпуса установлена подкладка. Подкладка выполнена с наклонными выштамповками, выступающими своими внутренними кромками из нее по обеим сторонам корпуса на толщину нижней части корпуса. Выштамповки снабжены местами для крепления к нижнему концу ленты. В центральной части под корпусом подкладка по оси симметрии выполнена с продольным вырезом, а по обеим концом она снабжена лапками, толщина которых к концам сведена до минимально возможной толщины, при этом ширина подкладки выполнена равной ширине ленты. Предложена такая конструкция хомута, которая позволяла бы уменьшить усилие стягивания концов ленты, создать за счет этого запас по усилию, обеспечив повышение надежности его работы. Кроме того, хомут должен обеспечивать создание более одной зоны обжатия шланга на патрубке для повышения надежности герметизации соединения. 7 ил.
Patent RU-2190913-C1 (RU)
Inventor: GRIN A V
IPC: H02G15/08
Filed: 2001-02-07
Granted: 2002-10-10
Abstract: FIELD: electrical engineering. SUBSTANCE: junction box has current-carrying conductor connector, insulator, two contact rings, two ground contact springs, cable screen wire connection assembly made in the form of two compressible copper sleeves, transverse sealing tube, and thermosetting tube. Insulator is monoblock structure incorporating electric-field strength leveling assembly in the form of two cones and central high-voltage electrode which enables smoothing inrush electric field intensity in vicinity of cable joints. EFFECT: reduced labor consumption for box installation and wiring, enhanced electric strength, service life, and reliability. 14 cl, 1 dwg
Patent RU-2184041-C1 (RU)
Inventor: ZHUKOVIN S M
IPC: B60L5/08
Filed: 2001-02-12
Granted: 2002-06-27
Abstract: FIELD: transport engineering; electric vehicles. SUBSTANCE: invention relates to current collectors of such vehicles as street cars or electric locomotives. Proposed current collecting element has metal frame on which carbon containing plate with contact surface and base is installed. Base is made in form of dovetail and it contacts with metal frame. Arc-shaped contact surface of plate is made with radius of 2-5 m and is provided with entry part with angle of tilting relative to plate base being 30-60 degrees. Height of plate in middle is 0.05-0.020 of radius of contact surface. Base in longitudinal section has form of trapezium with angle of tilting relative to horizontal equal to 5-15 degrees. EFFECT: improved wear resistance of current collecting element, increased service life of current collecting element owing to decrease of dynamic loads in current collector moving along contact wire. 2 cl, 2 tbl, 2 dwg
Patent RU-2189568-C1 (RU)
Title: Method of measurement of power characteristics of high-power optical radiation
Inventor: FILIPPOV O K
IPC: G01J5/58
Filed: 2001-07-10
Granted: 2002-09-20
Abstract: FIELD: measurement technology; power photometry; development of superbright radiation source: high-power electric arcs and lasers. SUBSTANCE: method of measurement of power characteristics of high-power radiation includes absorption of optical radiation and recording thermal response of absorbing element; absorption of radiation is effected on material at X-region of spectrum for radiation power isotherms; recording of thermal response of absorbing element is effected at wave length in X-region of spectrum at time delay found from the following dependence: τ del  = τ em.im , τ del ≥h 2 /a where τ em.im  is emission impulse duration and "a" is coefficient of thermal diffusivity of material of absorbing element and "h" is thickness of absorbing element. EFFECT: enhanced accuracy of measurements and enhanced reliability of measurements. 1 dwg, 1 tbl
Patent RU-2194541-C1 (RU)
Title: Method for treating locally generalized stomach cancer by applying combined therapy
Inventor: AFANAS EV S G
IPC: A61B17/00
Filed: 2001-07-13
Granted: 2002-12-20
Abstract: FIELD: medicine. SUBSTANCE: method involves administering two systemic polychemotherapy courses with 3 weeks long pause between the courses. The following treatment schedule is suggested. Metotrexate is intravenously administered at a dose of 5mg/m 2  as bolus dose from the first to the fifth day. Carboplatin is administered at a dose of 50mg/m 2  as 45 min long intravenous infusion from the first to the fifth day. 5-fluorouracyl is administered at a dose of   as 3 h long intravenous infusion from the first to the fifth day. Surgical intervention is carried out 3 weeks later, after the polychemotherapy course being over. Cisplatin is administered at a dose of 15mg/m 2  during the operation. EFFECT: enhanced effectiveness in treating III stage stomach cancer cases.
Patent RU-2197073-C1 (RU)
Inventor: KOSTIN V D
IPC: A01B49/02
Filed: 2001-09-11
Granted: 2003-01-27
Abstract: FIELD: agricultural engineering. SUBSTANCE: combined tillage tool has frame carrying succession of working members made in the form of A-hoes or shearing hoes, V-shaped leveler, ring rollers or star-wheeled rollers, bars of square, round or hexagonal section, and adjustable height spring-tooth harrows. Leveler is hung to frame by means of flexible hangers. Replaceable sprockets are mounted on shaft of second row of rolls and on shaft of left-hand bar beam, with number of sprockets being selected on condition that during operation bar be rotated in direction opposed to progressive motion of tillage tool and that ratio of progressive motion of tillage tool to peripheral speed of bar be within the range of 0.88-0.92. Tillage tool of such construction is adapted for presowing treatment of soil and provides moisture accumulating and moisture retaining technology of cultivation of agricultural crops in insufficient moistening zones. EFFECT: increased efficiency in weedage control, increased crop yield and reduced expenses for unit of agricultural product. 2 cl, 1 dwg
Patent RU-2197842-C1 (RU)
Title: Method of preparing candied berries
Inventor: KVASENKOV O I
IPC: A23L21/10
Filed: 2001-10-08
Granted: 2003-02-10
Abstract: FIELD: food-concentrates industry. SUBSTANCE: prepared berry raw material is saturated with carbohydrates in concentrated clarified fruit or berry juice with content of dry substances of 50-75% by mass with addition of a preparation. The preparation is produced by successive extraction of biomass of Mortierella dichotoma micromycete with nonpolar extracting agent under above-critical condition, water, alkali, water, acid, alkali and water with the following combination of the first extract with solid residue. Saturation is conducted at temperature lower than that of concentrated juice boiling up to 50-55% content of dry substances in raw material, and candied berries are dried up to 20-25% of residual moisture content. Using of extract of biomass of Mortierella dichotoma micromycete allows to strengthen cell structure of raw material, and it provides maintaining form and volume of berries in prepared product. The method provides preparation of candied berries with lower stickiness, mild taste, highly expressed aroma without caramel tints, delicate consistency, and products do not expose to changing of color. EFFECT: reduced losses of native biologically active substances with simultaneous improvement of chemical composition and increased yield. 3 cl
Patent RU-2197010-C1 (RU)
Inventor: SIL NIKOV M V
IPC: G02B27/48
Filed: 2001-11-20
Granted: 2003-01-20
Abstract: FIELD: individual protecting- illuminating means meant for illumination of objects and protective luminous action in case of threat of attack. SUBSTANCE: portable laser protective device has case housing power supply unit, semiconductor laser diode and lens mounted for movement along optical axis. Device is fitted with lens element made of at least two cylindrical lenses, one of them being fixed in case and another one being mounted for turn through angle multiple of 90 degrees with reference to initial position, for which position in which main sections of first and second lenses having same profile are perpendicular one another and main section of second lens is aligned with plane perpendicular to smaller side of radiating butt of luminous body of laser radiator and passes through center of its output window is adopted. Front focus of lens is aligned with radiating butt of luminous body. EFFECT: enhanced efficiency of security measures and protection against attack thanks to more accurate and directional action. 2 cl, 3 dwg
Patent RU-2197551-C1 (RU)
Inventor: SVENTSITSKIJ A T
IPC: C22C33/04
Filed: 2001-12-18
Granted: 2003-01-27
Abstract: FIELD: ferrous metallurgy, particularly, production of ferromanganese alloys from high-phosphorus manganiferous ores, particularly, concretions. SUBSTANCE: method includes preparation of charge, loading of charge into electric furnace, melting, holding of melts and tapping of heat products. Charge is melted at temperature of 1500-1650 C with maintaining ratio of iron oxides and phosphorus oxides to carbon within 0.4-0.95 of shoichiometric value. Hydrocarbon-containing component in charge is used in the form of liquid hydrocarbons, for instance, oil. EFFECT: simplified production technology of conversion manganese slag, increased quality of slag, and reduced losses of manganese with associated alloy. 2 cl
Patent RU-2198787-C1 (RU)
Title: Granulating screw extruder
Inventor: RAVICHEV L V
IPC: B29B9/06
Filed: 2001-12-25
Granted: 2003-02-20
Abstract: FIELD: processing of high-concentrated polydisperse materials with a high viscosity by the method of straightway molding, applicable in various branches of industry, for example, chemical, food and others. SUBSTANCE: the extruder includes a body, feeding screw and a multi-channel molder tool. The forming channels with contracting entering parts are made on the inner surface of the molder tool facing the mass flow. The contracting entering parts of the peripheral forming channels located in the recess of the multi-channel molder tool in the transient part between the inner surface of the body and the multi-channel molder tool make up a complex geometric surface. The above surface is obtained by combination of successively alternating surfaces: cylindrical, taper-cylindrical and tapered ones. EFFECT: prevented dead zones located in the periphery between the extruder body and the multichannel molder tool. 1 cl, 5 dwg
Patent RU-2214081-C1 (RU)
Inventor: KVASENKOV O I
IPC: A01N63/30
Filed: 2002-05-15
Granted: 2003-10-20
Abstract: FIELD: agriculture. SUBSTANCE: the present innovation deals with presowing seeds treatment in agricultural varieties. After thermal treatment seeds should be treated with immunostimulant as preparation containing the mixture obtained due to successive extracting Mortierella jenkinii micromycete biomass with nonpolar extragent in supercritical state with water, alkali, water, acid, water, alkali and water followed by combining the first extract with solid residue. The suggested technology enables to increase the quantity of preparations used for seeds treatment. EFFECT: higher efficiency.
Patent RU-2207918-C1 (RU)
Title: Floatation machine
Inventor: ZIMIN A V
IPC: B03D1/14
Filed: 2002-06-06
Granted: 2003-07-10
Abstract: FIELD: concentration of minerals by floatation method. SUBSTANCE: floatation machine has chamber, aeration unit with impeller located around bladed stator and connected with hollow shaft for delivery of air; foam layer volume and area regulator mounted in upper portion of chamber for vertical motion is made in form of cone whose vertex is directed downward. Circular chute is mounted additionally in center of chamber around base of cone at circular clearance with area of no less than 20% of area of cross-section of chamber; walls of this chute are located at angle no less than 10 deg. from vertical axis. Outer wall of chute is higher than inner wall. Circular chute is connected with foam chute by means of radial chutes. EFFECT: enhanced efficiency of floatation. 3 cl, 3 dwg _
Patent RU-2223048-C1 (RU)
Inventor: GARAEV V N
IPC: A61B17/00
Filed: 2002-06-04
Granted: 2004-02-10
Abstract: Изобретение относится к медицине, а именно к брюшной хирургии. Накладывают на лапаротомную рану восьмиобразный шов с образованием перехлеста лигатуры над апоневрозом путем проведения двойной лигатуры через мышечно-апоневротические слои брюшной стенки с захватом брюшины. Лигатуру в месте вкола или выкола иглы разводят и выполняют вколы иглами с разведенными одинарными лигатурами с двух сторон относительно места разведения лигатуры. Далее проводят нити внутрикожно с выколами на противоположном краю раны. После этого выведенную двойную и разведенные одинарные лигатуры стягивают и завязывают в узел. Способ позволяет достичь хорошей адаптации краев раны. 1 з.п. ф-лы, 3 ил.
Patent RU-2205656-C1 (RU)
Inventor: PILAT T L
IPC: A61K31/718
Filed: 2002-06-27
Granted: 2003-06-10
Abstract: FIELD: medicine, gastroentrology. SUBSTANCE: invention relates to parapharmaceutical industry producing preparations of curative and prophylactic designation that can be used for prophylaxis and accessory treatment of gastritis, duodenitis and colitis of different etiology, ulcer disease. Invention proposes biologically active supplement for prophylaxis and supporting therapy in digestive tract diseases. Supplement is based on medicinal plants and comprises the following components: glabrous licorice roots dry extract, elecampane roots dry aqueous concentrate, dry concentrates of Saint- -John's-wort herb tincture, propolis and carrot juice, flower pollen, vitamin E, zinc sulfate, aluminium hydroxide, milled oat, starch, calcium stearate, talc and sugar taken in definite weight ratios. The use of this supplement results to improvement of indices of T-cellular immunity revealing due to increased level of T-helpers, clinic indices in patients with pathology of digestive organs being for short times. EFFECT: valuable medicinal properties of supplement. 2 cl, 5 tbl, 4 ex
Patent RU-2225571-C1 (RU)
Title: Method for thermic deaeration of water
Inventor: SHARAPOV V I
IPC: F22D1/50
Filed: 2002-07-26
Granted: 2004-03-10
Abstract: FIELD: thermic deaeration of water, possibly in boiler aggregates. SUBSTANCE: method comprises steps of deaerating water in vacuum deaerator due to feeding to deaerator initial water and heating agent; sustaining predetermined concentration of dissolved oxygen in deaerated water by successively controlling temperature and flowrate of heating agent; when concentration of oxygen exceeds predetermined value at first increasing temperature of heating agent and then, if necessary increasing its flowrate; when concentration of oxygen becomes lower than predetermined value at first decreasing flowrate of heating agent and then lowering temperature of heating agent. EFFECT: enhanced efficiency and reliability of boiler aggregate. 1 dwg
Patent RU-2230211-C1 (RU)
Inventor: MOLCHANOV V F
IPC: F02K9/08
Filed: 2002-10-14
Granted: 2004-06-10
Abstract: FIELD: emergency rescue of flying vehicle crew. SUBSTANCE: proposed ejection seat cartridge includes sleeve, percussion primer, petard, solid-propellant grains, wad, lattice and gaskets. Solid-propellant grains are restricted-burning over external surface. Petard is made from molded black rifle powder with riffled surface directed towards percussion primer. Cardboard gaskets are laid in between end faces of propellant grains contacting petard and lattice. Ejection seat cartridge is provided with additional booster charge made from solid-propellant grains or granulated all-side burning powder whose mass is equal to 0.1-0.3 of mass of main charge. EFFECT: enhanced reliability of ejection seat cartridge. 2 cl, 4 dwg
Patent RU-2248778-C1 (RU)
Title: Method for removing subluxated eye lens
Inventor: KOPAEVA V G
IPC: A61F9/007
Filed: 2003-06-18
Granted: 2005-03-27
Abstract: FIELD: medicine. 
     SUBSTANCE: method involves carrying out paracentesis at 9-10 o'clock position. Cystostome end piece is introduced through the paracentesis in to the anterior chamber and perforation is done through pupil in the center of the anterior lens capsule. The capsule is pulled towards Zinn's ligament. Triangular flap is formed. The flap is thrown up over the anterior eye lens capsule. Cystostome is applied on the flap. First, 1/3 of anterior continuous circular capsulorhexis is carried out towards Zinn's ligament rupture. Then, capsule forceps is introduced through surgical incision and opposite peripheral capsule edge is fixed. The remaining part of capsulorhexis is carried out with formed flap being removed. Eye lens nucleus hydrodissection is carried out. Capsule ring is implanted. Eye lens nucleus phacoemulsification or cataract laser extraction is carried out. 
     EFFECT: enhanced effectiveness of treatment; avoided Zinn's ligament and continuous circular capsulorhexis edge rupture. 
     1 dwg
Patent RU-2242841-C1 (RU)
Inventor: AVRAMENKO M F
IPC: H04B10/10
Filed: 2003-07-14
Granted: 2004-12-20
Abstract: FIELD: optical communication systems including atmospheric ones. 
     
     
       SUBSTANCE: proposed optical communication line is characterized in reduced dependence of its energy potential on variations in typical cross-sectional area of optical transmitter radiation beams passed through atmosphere layer which is attained by evaluating impact of atmosphere on cross-sectional area dimensions of radiation beams of optical transmitters and compensating for their impact by varying divergence of these beams. 
     
     
       EFFECT: enhanced reliability of communications over proposed optical line. 
     
     
       1 cl, 1 dwg
Patent RU-2248573-C1 (RU)
Title: Express-diagnosis method for determining if mechanical injuries have been received in life time
Inventor: EHDELEV N S
IPC: G01N33/48
Filed: 2003-07-21
Granted: 2005-03-20
Abstract: FIELD: medicine. 
     SUBSTANCE: method involves studying whole blood or blood serum of cadaver by means of erythrocyte diagnosticum. Myoglobin concentration is determined. The concentration being equal to 32000 ng/l and higher in blood serum, conclusion is drawn that injuries were received in life time. 
     EFFECT: high accuracy of express-diagnosis.
Patent RU-2250978-C1 (RU)
Title: Method for extraction of lifting pipes column from a well
Inventor: KUSTYSHEV A V
IPC: E21B19/00
Filed: 2003-10-15
Granted: 2005-04-27
Abstract: FIELD: oil and gas industry. 
     SUBSTANCE: method includes collapsing upper portion of fountain armature, mounting suspended branch pipe with sleeve for being held by elevator, mounting elevator below sleeve of upper lifting pipe, unloading lifting pipe column onto elevator, turning off lifting pipes. After collapsing upper portion of fountain armature pipe catcher is lowered inside lifting pipes column on drilling pipe and then is connected inside lifting pipes column. Pipe catcher with lifting pipes column on it is then raised for value, enough to screw off holder of lifting column. Holder of lifting pipes is detached and column is unloaded onto packer. Pipe catcher is detached and extracted from well on drilling pipe. Lifting pipes holder is extracted from crosspiece of fountain armature. Suspension branch pipe with sleeve for being held by elevator is lowered into well, and screwed on uppermost lifting pipe. Lifting pipes column is pulled upwards with concurrent rightward rotation and then lifting pipes column is disconnected from packer. After that lifting pipes column is raised from the well. 
     EFFECT: higher efficiency. 
     3 dwg