baber/WOPTO huggingface dataset:
Patent UA-116023-C2 (UA)
Title: Ethynyl derivatives as metabotropic glutamate receptor antagonists
Inventor: JAESCHKE GEORG
IPC: C07D403/04
Filed: 2014-04-07
Abstract: The present invention relates to ethynyl derivatives of formula (I) wherein Y is N or CH; R1 is hydrogen, fluоrо or chloro; and R2 is hydrogen or lower alkyl; or to a pharmaceutically acceptable acid addition salt thereof. It has now surprisingly been found that the compounds of general formula (I) are melabotropic glulamate receptor antagonists (negative allosteric modulators) for use in the treatment of anxiety and pain, depression, Fragile-X syndrome, autism spectrum disorders, Parkinson's disease, and gastroesophageal reflux disease (GERD). EMBED ISISServer (I)
Patent UA-114148-C2 (UA)
IPC: C07D497/20
Filed: 2016-02-08
Abstract: 1. Об'єкт винаходу: 6-спіроконденсовані похідні [1,2,4]триазино[2,3-с]хіназоліну. 2. Галузь застосування: Хіміко-фармацевтична галузь. 3. Суть винаходу: 6-спіроконденсовані похідні [1,2,4]триазино[2,3-с]хіназоліну формули І,5. Технічний результат: Нові 6-спіроконденсовані похідні [1,2,4]триазино[2,3-с]хіназоліну які можуть виявляти широкий спектр біологічної дії, або можуть бути використані як "будівельні блоки" для синтезу невідомих біологічно активних речовин з направленою фармакологічною дією; відтворені в умовах вітчизняних промислових хіміко-фармацевтичних підприємств з використанням стандартного обладнання; синтезовані з доступних вихідних реагентів та мають низьку токсичність вихідних речовин та кінцевих продуктів.
Patent UA-121482-C2 (UA)
Title: Drug combinations to treat multiple myeloma
Inventor: AFTAB DANA T
Filed: 2015-08-05
Abstract: This invention relates to the combination of a C-Met inhibitor and a proteasome inhibitor to treat cancer, particularly multiple myeloma.
Patent UA-122905-C2 (UA)
Title: Method, machine and installation for vacuum packaging of products
Inventor: IZQUIERDO EREÑO ENEKO
Filed: 2016-06-28
Abstract: Method, machine and installation for vacuum packaging of products (P), where a plurality of individual bags closed at one end and open at the opposite end with at least one product (P) therein are generated. For generating the bags (1), a transverse cut and a complete transverse seal on both sides of the transverse cut are made on the film tube (3), and a transverse cut without complete transverse seals on the sides thereof is made at a distance (L) substantially equal to the desired length of the bag (1) to be generated from the transverse cut and seal on both sides. Each bag (1) is oriented at 180° with respect to the bag (1) previously generated in the forward movement direction (X).
Patent UA-120734-C2 (UA)
Title: Extraction fitting for liquid containers
Inventor: PAUL ULRICH
Filed: 2016-12-06
Abstract: Extraction fitting (10) for liquid containers, in particular for connecting to the outlet stub or the outlet opening of a transport and storage container for liquids, comprising a fitting housing (11) in which there is arranged a valve body, which can be pivoted about a valve axis by means of a handle (12), for opening and closing a throughflow cross section of an outlet pipe (13), wherein the handle is provided with a handle stop and a housing dome of the fitting housing is provided with a housing stop, which stops can be arrested in their relative position by means of a securing device (16) to secure the shut-off position, wherein the securing device (16) comprises a stop bar (17) which can be moved translationally in the direction of the valve axis between a locking position and an unlocking position.
Patent UA-123476-C2 (UA)
Title: Спосіб одержання засобу з діуретичною дією з листя мучниці звичайної та валіну
Filed: 2019-08-15
Abstract: Винахід належить до галузі фармації та медицини, а саме до способів одержання біологічно активних речовин з природної сировини, і стосується способу одержання лікувально-профілактичних засобів діуретичної дії з листя мучниці звичайної з додаванням валіну, що впливають на діурез при лікуванні захворювань, пов'язаних з порушеннями роботи сечовивідної системи.
Patent UA-125426-C2 (UA)
Title: Композиція для лікування генералізованого парадонтиту у осіб з дефіцитом секреторного імуноглобуліну а
Filed: 2021-03-03
Abstract: Винахід належить до медицини, а саме до стоматології, і може бути використаний для лікування генералізованого пародонтиту у осіб з дефіцитом секреторного імуноглобуліну А та стосується композиції, що складається з препаратів: аскорбінової кислоти, рутину, мазі календули, білої глини, окису цинку та деринату, яка має виражену протимікробну, протизапальну, імуномодулюючу, антиоксидантну, репараційну дії.
Patent UA-76273-C2 (UA)
Title: Turner
Inventor: DUDKA ANATOLII IVANOVYCH
IPC: B22D41/06
Filed: 2004-07-12
Abstract: The invention relates to the metallurgy and concerns the mechanisms for turning of the cups of slag carriages. The mechanism consists of an electric motor, a reducer, gears fixed by upper and lower screws with the nuts, posts, a traverse. The nuts are fixed in the tubular guides from the side of the posts, opposite end of which enters into the grooves of the traverse, and tubular guides are closed with cylindrical jacket fixed on the post from the side of nuts. Technical result is an increase of the reliability and service life of the screw pair.
Patent UA-81756-C2 (UA)
Title: Normal;heading 1;heading 2;CONTROLLED RELEASE ORAL DOSAGE FORM
Inventor: MARTINI LUIGI
IPC: A61K9/20
Filed: 2003-12-02
Abstract: An oral dosage form comprising, (i) an erodable core, which core comprises a pharmaceutically active weak base or a pharmaceutically acceptable salt or solvate thereof; and (ii) an erodable coating surrounding said core, which coating comprises one or more openings extending substantially completely through said coating but not penetrating said core and communicating from the environment of use to said core; characterised in that release of the pharmaceutically active weak base or a pharmaceutically acceptable salt or solvate thereof from the dosage form occurs through the said opening(s) by the erosion of said erodable core and through erosion of said erodable coating under pre-determined pH conditions; a process for preparing such a dosage form and the use of such a dosage form in medicine.
Patent DE-19632154-C5 (DE)
Title: Haldenabdeckung und Verfahren zur Herstellung derselben
Inventor: DEMMICH JOERG
IPC: B65G3/02
Filed: 1996-08-09
Granted: 2004-07-08
Abstract: Haldenabdeckung, bestehend aus hydraulisch und puzzolanisch abgebundenen Gemischen mineralischer Reststoffe, insbesondere aus einem oder mehreren Kraftwerksreststoffen, Aschen aus der Verbrennung von Klärschlamm, Biomassen, Holz, Papierschlamm und/oder gipshaltigen Reststoffen, welche zur Haldeninnenseite hin verdichtet sind und zur Haldenaußenseite hin lockerer strukturiert sind.
Patent DE-19654188-C5 (DE)
Title: Filterelement und Verfahren für dessen Herstellung
Inventor: KOMETANI KAZUO
IPC: B01D46/24
Filed: 1996-12-23
Granted: 2010-09-23
Abstract: Filterelement mit einem Filterabschnitt (100F), der eine Mehrzahl von gefalteten Abschnitten hat und einem Flanschabschnitt (20), der einstückig mit einer äußeren Peripherie des Filterabschnitts (100F) ausgebildet ist, dadurch gekennzeichnet, daß der Flanschabschitt (20) folgende Elemente hat:  einen dicken Dichtungsabschnitt (33, 233, 321) und  einen Lippenabschnitt (23, 123, 220, 335, 336), der in eine Richtung entgegengesetzt zu dem Dichtungsabschnitt (33, 233, 321) vorsteht, einen V-förmigen oder einen rechtwinkligen Querschnitt hat und wesentlich höher als der Dichtungsabschnitt ist.
Patent DE-59106858-C5 (DE)
Title: Werkzeugmaschine mit einem Kopf zur Erzeugung eines Lasterstrahls zur Bearbeitung und zum Trennen von Rohren.
Inventor: ANDREATTA LIVIO
IPC: B23K26/08
Filed: 1991-10-16
Granted: 2008-04-03
Abstract: Nichtig
Patent DE-102006044626-C5 (DE)
Title: Aufkohlungsbehandlungsvorrichtung und -verfahren
Inventor: KATSUMATA KAZUHIKO
IPC: C23C8/20
Filed: 2006-09-19
Granted: 2011-04-28
Abstract: Aufkohlungsbehandlungsvorrichtung (S1), die eine Aufkohlungsbehandlung durch Erwärmung eines in einer Behandlungskammer (31) zu behandelnden Gegenstandes (W) durchführt, deren Innenseite unter verringertem Druck steht, sowie in einer Aufkohlungsgasatmosphäre, die Folgendes umfasst:  Eine Temperaturmesseinrichtung zum Messen von Temperaturen in einer Mehrzahl von Bereichen (R1, R2, R3) innerhalb der Behandlungskammer (31), und  eine Temperatureinstelleinrichtung zur individuellen Einstellung von Temperaturen in der Mehrzahl von Bereichen (R1, R2, R3) auf der Grundlage von Messergebnissen der Temperaturmesseinrichtung, so dass der zu behandelnde Gegenstand (W) mit einer einheitlichen Aufkohlungsbehandlung versehen wird, wobei die Temperatureinstelleinrichtung ein Heizelement (11–16), welches an jedem der Bereiche (R1, R2, R3) angeordnet ist, und eine Steuereinrichtung zur individuellen Steuerung des Heizelementes (11–16) auf der Grundlage der Messergebnisse der Temperaturmesseinrichtung aufweist, wobei es selbst dann, wenn die Temperaturen innerhalb der Isolationskammer (31) während der Aufkohlungsbehandlung verändert werden, möglich ist, dieselbe Temperatur in derselben Geschwindigkeit des zu behandelnden Gegenstandes (W) zu verändern, die...
Patent DE-102008061250-C5 (DE)
Title: Staubsaugerbeutel und Verfahren zur Herstellung eines Staubsaugerbeutels
Inventor: CZADO WOLFGANG DR
IPC: A47L9/14
Filed: 2008-12-10
Granted: 2018-12-20
Abstract: Staubsaugerbeutel (1) aus Vliesstoff, mit einem Innenraum (8), der von Lagen aus Filtermaterial umgeben ist, die miteinander verschweißt sind, wobei eine Einlassöffnung in dem Filtermaterial ausgebildet ist, dadurch gekennzeichnet, dass in dem Innenraum (8) mindestens eine Vorrichtung (10) zur Begrenzung des Abstandes zweier beabstandeter Stellen des Filtermaterials vorgesehen ist, die an gegenüberliegenden Seiten mit dem Filtermaterial verbunden ist, wobei die Vorrichtung (10) kürzer als der Materialabschnitt des Filtermaterials ausgebildet ist, der zwischen den zwei Stellen der Vorrichtung (10) an dem Filtermaterial angeordnet ist, wobei der Staubsaugerbeutel (1) als Klotzbodenbeutel ausgebildet ist und an gegenüberliegenden Seiten jeweils eine nach innen gerichtete Falte (6) vorgesehen ist und die als Streifen ausgebildete Vorrichtung (10) an den Falten (6) festgelegt ist.
Patent DE-102010027176-C5 (DE)
Title: Plakatpräsentationsvorrichtung und Werbevitrine
Inventor: ZILLESSEN HARALD
IPC: G09F15/00
Filed: 2010-07-14
Granted: 2013-11-21
Abstract: Die Erfindung betrifft eine Plakatpräsentationsvorrichtung mit einem Tragekörper und einem Plakat, welches zur Präsentation mit Hilfe einer Befestigungsvorrichtung an dem Tragekörper aufgehangen ist, derart, dass ein oberer Plakatrand in Horizontalrichtung verlaufend angeordnet ist, wobei die Befestigungsvorrichtung mit zwei Befestigungsstrukturen gebildet ist, bei denen jeweils ein Befestigungselement, welches an dem Tragkörper befestigt ist, und ein zugeordnetes Befestigungselement, welches an der Plakatrückseite befestigt ist, zusammenhaltend und entlang einer Verschiebebahn relativ zueinander verschiebbar gebildet sind, und wobei die Verschiebebahnen der zwei Befestigungsstrukturen zur Horizontalrichtung schräg und zu entgegengesetzten seitlichen Plakaträndern hin abfallend verlaufen. Des Weiteren betrifft die Erfindung eine Werbevitrine mit zumindest einer Plakatpräsentationsvorrichtung.
Patent DE-102013204504-C5 (DE)
Title: Flügelzellenpumpe mit verbesserter Leistung
Inventor: PETERS SVEN
IPC: F04C2/344
Filed: 2013-03-14
Granted: 2016-06-09
Abstract: Flügelzellenpumpe mit einem Pumpengehäuse, einem Stator, der durch das Pumpengehäuse zumindest teilweise gebildet oder in dem Pumpengehäuse angeordnet ist, einem Rotor, der in dem Stator exzentrisch angeordnet und relativ zu dem Stator um eine Rotorrotationsachse drehbar ist, wobei der Rotor eine Welle und wenigstens einen Rotorflügel umfasst und der Rotorflügel bei einer Drehung des Rotors in einer Öffnung der Welle in einer Richtung quer zur Rotorrationsachse beweglich gelagert ist, wobei die Öffnung in einem ersten Bereich, der sich von einem Außenrand der Welle in die Welle hinein erstreckt, eine Form aufweist, die im Wesentlich einer Außenform des Flügels entspricht und wobei die Öffnung in dem ersten Bereich eine im Wesentlichen dichtende Führung für den Flügel bildet, und wobei die Öffnung einen sich an den ersten Bereich anschließenden zweiten Bereich aufweist, indem wenigstens eine Tasche gebildet ist.
Patent RU-2550871-C9 (RU)
Title: Штамп для морфологической модификации полимеров, способ его получения и способ формирования супергидрофильных и супергидрофобных самоочищающихся покрытий с его использованием
Inventor: ELISEEV ANDREJ ANATOL EVICH
IPC: B32B5/20
Filed: 2010-08-16
Granted: 2016-05-10
Abstract: Изобретение относится к области нанотехнологий и касается штампа для морфологической модификации полимеров, способа его получения и способа формирования супергидрофильных и супергидрофобных самоочищающихся покрытий с его использованием. Штамп представляет собой пленку пористого анодного оксида алюминия со средним расстоянием между центрами пор от 30 до 700 нм и обладает иерархической шероховатостью в диапазоне от 10 нм до 10 мкм с характерным размером элементов макрорельефа в диапазоне 1-10 мкм и размером элементов микрорельефа в диапазоне 10-500 нм. Способ получения указанного штампа включает контролируемое создание элементов макрорельефа путем механического или химического воздействия, например штамповки, чеканки или литографически с последующим анодным окислением алюминия в диапазоне напряжений от 5 до 300 В для создания микрорельефа. Способ включает модификацию поверхности полимера путем репликации структуры указанного штампа и последующего его механического удаления. Изобретение обеспечивает варьирование угла смачивания поверхности полимерных пленок в широких пределах, создание супергидрофильных и супергидрофобных поверхностей, низкую материалозатратность производства, повышение точности и однородности отпечатка. 3 н. и 14 з.п. ф-лы, 2 табл., 2 пр., 10 ил.
Patent DK-75183-D0 (DK)
Inventor: LAUERMANN GEORG
IPC: A01N59/12
Filed: 1983-02-22
Abstract: This invention is directed to a preparation useful on dairy animals. More specifically, this invention is directed to a preparation for the disinfection of teats and the care of udders of dairy animals which comprises: (a) from about 84.4 to 91.6 percent by weight, based upon the weight of the total preparation, of deionized water; (b) from about 3 to 5 percent by weight, based upon the weight of the total preparation, of glycerin; (c) from about 3 to 5 percent by weight, based upon the weight of the total preparation, of paraffin oil; (d) from about 1 to 2.5 percent by weight, based upon the weight of the total preparation, of saturated C16-C18-fatty alcohols; (e) from about 0.4 to 0.6 percent by weight, based upon the weight of the total preparation, of an iodine complex with disinfecting action, wherein the content of active iodine is from about 800 to 1200 ppm and the viscosity is from about 25 to 35 sec. as measured at 20 DEG C. in a Ford beaker with a 4 mm nozzle.
Patent DK-277989-D0 (DK)
Inventor: LARSEN BOERGE
IPC: A01D34/66
Filed: 1989-06-07
Abstract: PCT No. PCT/DK90/00138 Sec. 371 Date Dec. 6, 1991 Sec. 102(e) Date Dec. 6, 1991 PCT Filed Jun. 6, 1990 PCT Pub. No. WO90/14754 PCT Pub. Date Dec. 13, 1990.A disc cutter bar including an upper part and a lower part which are welded together along an edge to form a housing for a row of gear wheels through which cutter discs are driven. The bar is provided with an elongation extending rearwardly in cross-section from the gear wheel row, which partly results in an increase of the stiffness and strength of the bar with a simultaneous low constructional height and partly makes it possible to increase the oil amount in the housing.
Patent DK-440789-D0 (DK)
Inventor: HAENGGI ROBERT ARNOLD
IPC: E01F9/04
Filed: 1989-09-06
Abstract: A skid-resistant pavement marking sheet including a top surface (20) and a plurality of skid-resistant ceramic spheroids (22) embedded in and protruding from the surface (20). The ceramic spheroids (22) are fired from a raw material mixture including 10-97 wt. % mineral particulates, 3-90 wt. % alumina, and at least 1 wt. % binder, at a temperature of about 1300 DEG C, have an outer surface rich in alumina concentration relative to the center of the spheroid, and are resistant to crushing and fracturing.
Patent DK-485287-D0 (DK)
Inventor: ROSENBERG ROBERT D
IPC: C12N15/09
Filed: 1987-09-16
Abstract: A megakaryocyte stimulatory factor (MSF), purified to homogeneity, is an acidic protein (pI = 5.1) with an Mr 15,000 which stimulates PF4-like protein synthesis in rat promegakaryoblast cells by as much as 7-fold, and exhibits half-maximal activity at a concentration of 0.8 pM. MSF exhibits no biologic activity corresponding to other known hemopoietic growth factors, and appears to be specific for the megakaryocyte lineage. In the given examples, MSF was purified to homogeneity (as judged by SDS-PAGE and isoelectric focusing in the presence of 9.2 M urea) from serum-free conditioned medium obtained from cultured human embryonic kidney (HEK) cells, and to near homogeneity from thrombocytopenic plasma. The MSF is isolated by precipitating the MSF with ammonium sulfate at 80% saturation, removing insoluble, non-MSF material and applying the soluble protein to a WGA-Sepharose column, eluting the MSF protein with chitin oligosaccharides, applying the concentrated eluant containing MSF activity to a Biogel P200 column, and chromatographing the eluted MSF fractions on a TSK-G3000 HPLC size exclusion column.
Patent DK-511289-D0 (DK)
Inventor: SVENSSON GUNNAR
IPC: F28F/
Filed: 1989-10-16
Abstract: The present invention relates to a rotary heat exchanger (10) for recovering heat or cold and/or moisture from gas flows. The heat exchanger comprises a casing (12) which incorporates gas-flow channels (16, 18). The heat exchange rotor (22) forms part of a withdrawable rotor unit (55), which also includes a frame (28) on which the rotor is journalled, a transverse wall (56) having an opening for accommodating the rotor, a rotor drive motor (40), and a cover plate (38) which is intended to cover an opening (36) in the casing (12) through which the rotor unit can be withdrawn. Arranged between the transverse wall (56) and the peripheral surface (62) of the rotor (22) is a radially directed peripheral seal (60), to which is connected within the area of the frame (28) an axial seal (82) and a diametrical seal (48) respectively.
Patent DK-602087-D0 (DK)
Inventor: MURPHY TIMOTHY F
IPC: C12N1/21
Filed: 1987-11-17
Abstract: A plasmid which contains a genetic code for an immunogenic portion which is conserved in many strains of nontypable Haemophilus influenzae and the bacterium containing this plasmid is disclosed. The immunogenic portion is preferably an epitope on an outer membrane protein of H. influenzae. A monoclonal antibody to the immunogenic portion and the hybridoma which will produce the monoclonal antibody is also included. The invention further includes a DNA probe constructed to correspond to the nucleic acids which code for the immunogenic portion. This probe may be labelled with a radioactive marker and may be used as a diagnostic tool to assay various clinical samples for the presence of H. influenzae.
Patent DK-663687-D0 (DK)
Inventor: LUNDGREN DAN
IPC: A61M1/00
Filed: 1987-12-16
Abstract: PCT No. PCT/SE87/00201 Sec. 371 Date Dec. 19, 1988 Sec. 102(e) Date Dec. 19, 1988 PCT Filed Apr. 21, 1987 PCT Pub. No. WO87/06122 PCT Pub. Date Oct. 22, 1987.Implant passageway for connection of body cavities or body vessels to a device, container or the like externally of the body. It comprises an element (11) which consists of a biocompatible material or has a biocompatible outside layer. This element forms a socket (13) with a through passage (14) and on the outside of the curved surface thereof inwardly of an end portion (15) having a smooth outside surface, forms radial flanges (16) mutually spaced axially and defining between radial surfaces thereof peripheral grooves for growth of surrounding tissue thereinto.
Patent HU-9301728-D0 (HU)
Title: Method for producing formyl-tetrahydro-pyranes
Inventor: BRENNER KARL
IPC: C07D309/06
Filed: 1991-12-03
Abstract: Disclosed is a method for the preparation of formyltetrahydropyrans (I) by dehydrogenating hydroxymethyltetrahydropyrans (II) in the presence of a copper, silver and/or gold catalyst. The formyltetrahydropyrans (I) thus obtained are useful intermediates in the preparation of pharmaceuticals and phytopathalogical products.
Patent HU-913214-D0 (HU)
Title: Improved process for cleaning acetaminophene
Inventor: FRUCHEY STANLEY O
IPC: C07C233/25
Filed: 1991-10-10
Abstract: A method is provided for purifying a crude N-acetyl-para-aminophenol (APAP) containing color bodies or their precursors, the method comprising: a) forming a hot aqueous solution of the crude APAP; and b) subsequently contacting the hot solution with an acid washed adsordent carbon, e.g., an activated carbon, which acid washed carbon, prior to such contact, has been pretreated by contacting it with an aqueous solution of a reducing sulfite.
Patent HU-905030-D0 (HU)
Title: Process for producing new 1,3-oxazines and pharmaceutical preparatives containing these compounds
Inventor: BALLHAUSE HELMUT
IPC: C07D265/06
Filed: 1990-08-15
Abstract: Novel compounds of the general formula   <IMAGE> I  which have antitussive activity, wherein R1-R4 are as defined herein.
Patent NO-863425-D0 (NO)
Inventor: TECINSKY JAROSLAV
IPC: H02K16/00
Filed: 1986-08-26
Abstract: PCT No. PCT/DE85/00552 Sec. 371 Date Sep. 11, 1986 Sec. 102(e) Date Sep. 11, 1986 PCT Filed Dec. 20, 1985 PCT Pub. No. WO86/04467 PCT Pub. Date Jul. 31, 1986.A numerically-controlled electromechanical precision drive system in which a plurality of low-current servomotor units are arranged in a circle around the driven shaft or push rod of an intermediate gear-wheel in such a way that pinion gears linked with its driven shaft engage with the intermediate gearwheel. The motor units are each driven in synchronism and are each independently linked with an emergency power supply and drive electronic system which receives the control pulses from a joint electronic control system, thus producing a multi-torque drive which provides the operating shaft with a rotational and/or translatory movement.
Patent NO-873319-D0 (NO)
Inventor: GLANG SIEGFRIED
IPC: E21D11/38
Filed: 1987-08-07
Abstract: There is provided a sealing profile formed of rubber or rubber-like material for tunnel segments having a recess therefor extending therearound, the profile having a base side facing the segment and a back side facing away from the segment, a plurality of longitudinally extending parallel flutes in the base side, lateral flanks extending angularly from the base side, a plurality of longitudinally extending parallel ducts, and at least one centrally disposed bridge through extending from the base side to the back side without impairment in its supporting effort by a longitudinal duct.