baber/WOPTO huggingface dataset:
Patent AU-2014346342-C1 (AU)
Title: Compositions and methods for producing genetically modified animals
Inventor: KOENTGEN FRANK
IPC: C12N5/10
Filed: 2014-11-07
Granted: 2020-08-13
Abstract: Methods, compositions and non-human animals and parts thereof are disclosed for improving germ line transmission of genetic modifications. More particular, the present invention discloses methods and compositions for producing non-human embryos with a disrupted or disruptable fertility gene, which can be used as hosts for the development of donor pluripotent cells, including genetically modified donor pluripotent cells, into germ cells and gametes. Also disclosed are methods and compositions for producing from such embryos chimeric non-human animals with a disrupted fertility gene and for breeding the chimeric non-human animals with cognate non-human animals that comprise a fertility gene that lacks a disruption to produce non-human animals having substantially all gametes and/or germ cells derived from the donor pluripotent cells. The present invention also discloses non-human gametes, germ cells, embryos and animals for use in the subject methods.
Patent AU-2015209452-C1 (AU)
Title: CRF1 receptor antagonists for the treatment of congenital adrenal hyperplasia
Inventor: GRIGORIADIS DIMITRI E
IPC: A61K31/519
Filed: 2015-01-21
Granted: 2020-11-05
Abstract: CRF
Patent AU-2016269447-C1 (AU)
Title: Modulation of nuclear-retained rna
Inventor: BENNETT C FRANK
IPC: A61K48/00
Filed: 2016-12-06
Granted: 2019-06-20
Abstract: Abstract Provided herein are methods, compounds and compositions for reducing expression of a nurclear-retained RNA'nrRNA' in an animal. Also provided herein are methods compounds and compositions for treating, ameliorating, delaying or reducing a symptom of a disease or disorder associated with a nrRNA in an animal.
Patent RU-2168161-C1 (RU)
Inventor: URETSKIJ JA S
IPC: G01M7/00
Filed: 2000-02-01
Granted: 2001-05-27
Abstract: FIELD: testing and vibration protecting equipment. SUBSTANCE: random vibration actions are formed in working range of frequencies in points of attachment of elastically damping members to platform of vibration bed in multichannel vibration protecting system composed of protected object and elastically damping members linked to it. Values of inherent and mutual spectral densities of accelerations as well as values of mutual spectral densities of reaction of system and vibration actions are measured. System is put on platform of vibration bed capable of inhomogeneous elastic damping properties. Values of inherent and mutual densities of accelerations in points of attachment are set in each frequency band of working range. Random narrow-band signals are formed. Values of inherent and mutual spectral densities of accelerations in points of attachment are measured in each narrow frequency band. Values of all products of complex transfer functions of vibration paths in points of attachment computed in pairs by functions complexly dependent on them are determined by measured values. Values of gain factors of former of random narrow- band signals are found by measured values of inherent and mutual spectral densities of accelerations and by values of all computed products. Values of mutual spectral densities of accelerations in points of joint of elastically damping members and protected object and of accelerations in points of attachment of elastically damping members to platform of vibration bed are measured in each frequency band of working range. Values of complex transfer functions of elastically damping members and values of complex transfer functions of members of structure of protected object located between points of their joint to elastically damping members are found by values of inherent and mutual spectral densities of accelerations set and measured in each frequency band of working range. EFFECT: increased informativity and quality of investigation. 1 dwg
Patent RU-2167051-C1 (RU)
Title: Cleaving sawing device
Inventor: KOPANEV V D
IPC: B27B33/14
Filed: 2000-03-31
Granted: 2001-05-20
Abstract: FIELD: wood-sawing equipment, in particular, chain saws. SUBSTANCE: device has a truck, whose wheels are installed on metal guides placed in parallel with the log to be sawn. The truck carries a carriage with a self-movement mechanism and a swinging system in the form of a rigid framework. The framework is provided with a gasoline engine, reduction gear, sawing apparatus in the form of a bar and saw chain, and components for transmission of motion to these units, the sawing apparatus bar thickness equals 3.5 mm, and the saw chain thickness - 4.5 m. EFFECT: reduced power consumption, reduced time for fulfillment of one and the same operation, reduced wear of equipment, and prevented useless conversion of part of the wood to sawdust. 4 cl, 5 dwg
Patent RU-2175302-C1 (RU)
Inventor: SOKOLOV A V
IPC: B65D5/52
Filed: 2000-04-18
Granted: 2001-10-27
Abstract: FIELD: packing. SUBSTANCE: invention can be used for storing, transporting and showing of articles, for instance, eggs packed in boxes. Cardboard container has removable cover and housing consisting of bottom and vertical side walls. Shaped weakened strength line is made on one of walls which limits panel separated from side wall to form inspection opening facilitating access to articles placed in container. Panel is provided with vertical slots made from upper edge of side wall to provide possibility of fitting the panel on upper part of one of side walls by means of these slots after opening of container. Advertisement inscriptions and/or pictures are applied to separable panel. Maximal size of separable panel in height is 0.50-0.95 of height of side wall from which panel is separated, and maximum size in width of panel is 0.50-0.90 of width of corresponding side wall. EFFECT: improved convenience in use, increased rigidity of open container, enlarged operating capabilities of container owing to opposability of using of separable panel as advertising panel installed on upper part of one of side walls after opening of container. 5 cl, 2 dwg
Patent RU-2167690-C1 (RU)
Inventor: RUBCHENKO V N
IPC: A63B23/02
Filed: 2000-04-28
Granted: 2001-05-27
Abstract: FIELD: sportive equipment. SUBSTANCE: exercising apparatus has frame with supports, bedding mounted on frame, and rotary mechanism. Bedding has transverse planks and flexible washers joined one to the other by flexible connection. Rotary mechanism is mounted under bedding. Rear part of frame is made in the form of guide. Shin attachment mechanism is mounted for movement along guide. Weight is secured to shin attachment mechanism by cord. Head and axillary region fasteners are positioned in front part of frame. Apparatus is used for preventive treatment of vertebral column by combined working of circular flexibility and straining. EFFECT: increased efficiency and simplified construction. 3 cl, 3 dwg
Patent RU-2179884-C1 (RU)
Title: Hydrocarbon stock pyrolysis catalyst
Inventor: ADEL SON S V
IPC: B01J23/22
Filed: 2000-06-29
Granted: 2002-02-27
Abstract: FIELD: petroleum processing and petrochemistry. SUBSTANCE: pyrolysis catalyst for production of unsaturated hydrocarbons suitable for production polymers and rubbers consists of active component and carrier: kaolin and chamotte powder, whereas active component is proposed to be vanadium oxide and potassium carbonate supplemented by sodium acetate as modifier. Catalyst is finally composed of, wt %: vanadium oxide 2.0- 6.0, potassium carbonate 1.0-6.0, sodium acetate 0.05-3.0, kaolin 12.0-35.0, chamotte powder - the rest. Yield of ethylene and propylene in presence of such catalyst is increased to 52-54% and yield of coke lowered to 0.5%. EFFECT: increased selectivity of catalyst. 1 tbl
Patent RU-2177325-C1 (RU)
Title: Method of preparing substance eliciting immunostimulating activity
Inventor: TSEPELEV V L
IPC: A61K35/12
Filed: 2000-09-19
Granted: 2001-12-27
Abstract: FIELD: medicine, medicinal industry. SUBSTANCE: invention relates to method of preparing substance from poultry bursa of Fabricius eliciting immunostimulating activity. Raw is subjected for three-fold freezing at minus 40 C alternating with thawing out followed by homogenization. Homogenate is poured with 0.1 N acetic acid solution and phenylmethylsulfonylfluoride is added in concentration 0.1 mM. Extraction is carried out for 30-60 min, extract is filtered off, centrifuged and cooled acetone is added to filtrate for precipitate formation. Precipitate is filtered off, washed out with pure acetone and dried. Obtained powder is dissolved in 0.1 N acetic acid, solution is centrifuged, supernatant is subjected for gel-filtration on Toyopearl HW-40 and fractions of molecular mass from 300 to 3000 Da are collected. Invention provides to enhance immunostimulating activity by 10 times. EFFECT: improved method of preparing, enhanced activity, decreased therapeutical dose and risk of adverse effects. 9 tbl
Patent RU-2167035-C1 (RU)
Inventor: KAPUSTIN O E
IPC: B23K5/22
Filed: 2000-09-27
Granted: 2001-05-20
Abstract: FIELD: gas-flame treatment of materials, possibly at explosion hazard condition as additional equipment for protection against fires and explosions. SUBSTANCE: flame is localized due to setting direction of flame from inwards to outer surface of flame-extinguishing sleeve. Said sleeve has relation of areas of its outer and inner surfaces respectively Fout/Fin more than 1.2. Outer surface of flame-extinguishing sleeve is finned. Bushing is mounted with possibility of separating inner cavity of flame extinguishing sleeve from non-return valve and closing inner cavity by means of outer side of its bottom. Plunger spring is arranged in bushing; there are openings in wall of bushing for connecting annular cavity with inlet opening through seat of valve. Inner side of bottom of bushing serves as stopper. Annular cavity and inner cavity of flame-extinguishing sleeve have volumes selected according to relation Van/Vin more than 2, where Van - volume of annular cavity, Vin-volume of inner cavity. Surface of outlet opening has roughness degree Rz selected according to relation Rz/dout=0.015-0.2, where dout - diameter of outlet opening. Such structure provides lowered by 2 times emergency hazard due to increased time period of flame passage and detonation speed lowered by 2 times. EFFECT: improved operation reliability. 4 cl, 1 dwg
Patent RU-2182943-C1 (RU)
Title: Road pavement
Inventor: SHALYGANOV EH F
IPC: E01C5/18
Filed: 2000-12-22
Granted: 2002-05-27
Abstract: FIELD: road building. SUBSTANCE: invention relates to building of roads and can be used at laying the roads in any earth bases, construction of railway crossings, sidewalks, play grounds, parking and airfields. Proposed pavement is made of plates and recycled tire members interconnected by metal braces passing inside plates. Novelty is that recycled tire members are made in form of metal-cloth or cloth carcasses of tires radially cut in thickness with radial notches on tire sides straightened into flat sheet. Sheets are arranged one over the other in plate which is additionally provided with lining and covering sheets of elastomer material and entire structure is cured into monolith. EFFECT: increased strength, improved service characteristics, provision of reliability of pavement. 4 dwg
Patent RU-2183553-C1 (RU)
Title: Edger attachment
Inventor: SHOSTAK M N
IPC: B27B5/04
Filed: 2001-01-30
Granted: 2002-06-20
Abstract: FIELD: forestry. SUBSTANCE: edger has sawing mechanism made in the form of left- hand and right-hand sawing units equipped with plates. Saw width adjustment mechanism is formed as centering bearing secured to its plate and provided with right-hand and left-hand screws located inside bearing. Sawing units and saw width adjustment mechanism are mounted on single shaft allowing sawing units and saw width adjustment mechanism to be jointly turned, and sawing units are also allowed to effect straight synchronous motion in opposite directions with respect to centering bearing of saw width adjustment mechanism. EFFECT: simplified construction and increased efficiency. 6 dwg
Patent RU-2174923-C1 (RU)
Title: System for providing monitoring, information services and protection of mobile objects from unauthorized actions
Inventor: EFIMTSEV A A
IPC: B60R25/00
Filed: 2001-02-13
Granted: 2001-10-20
Abstract: FIELD: communication systems. SUBSTANCE: system provides locking engines of transport vehicles using paging communication network and putting beacon type transmitters into operation. Transceivers of street and road service system receive signals from the transmitters and take bearings on them. Signal power is measured and the data are transmitted to the base stations. The stations are connected to traffic supervision center making primary processing of the received data. Transport vehicle coordinates and the number of its transmitter switching-on acts are determined in information centers giving services to the prescribed group of objects for making financial settlements. The information centers receive and process data from external information sources and submit messages into territorial distributed network of centers carrying out emergency response to facts of unauthorized actions exerted upon the objects under guard. Transport vehicle owners have transponder card with secret locking, beacon and settlement codes saved. Identification code is stored in digital memory. The latter is read in remote access mode from the card for unlocking the engine. EFFECT: enhanced effectiveness and reliability of protection; wide range of features for commercial use. 2 dwg
Patent RU-2181868-C1 (RU)
Title: Barrel-type antiaircraft mount
Inventor: SMIRNOV JU P
IPC: F41A23/00
Filed: 2001-03-13
Granted: 2002-04-27
Abstract: FIELD: military equipment, applicable in stationary ground and naval artillery mounts. SUBSTANCE: the barrel-type antiaircraft mount has a rocking part in the form of a cradle with the weapon, rotating part and a base with the main elevating and training drives, intermediate rocking part with an auxiliary elevating drive, additionally installed between the base and the rotating part are hinge-joined on one side and the auxiliary elevating drive on the other side are the intermediate rocking and intermediate rotating parts, the intermediate rocking part is also linked with the rotating part by a turning pair and the main training drive, and the intermediate rotating part is linked with the base by a turning pair and the auxiliary training drive. EFFECT: enhanced efficiency of fire at air targets due to increased duration of fire in the zone of the most proximity of the target to the mount. 1 dwg
Patent RU-2187261-C1 (RU)
Inventor: PAVLOV V V
IPC: A61B17/24
Filed: 2001-05-21
Granted: 2002-08-20
Abstract: FIELD: medicine, stomatology. SUBSTANCE: access to deformation is obtained by separating a cartilage in a sagittal plane from perpendicular plate of ethmoid bone at the rear up to anterior nasal spina bluntly along fractures lines, after repairing osseous fragments a cartilage strip is placed into an osseous "framework", where a cartilage was situated before a trauma. The method restores nasal breathing and keeps the support of external nose. EFFECT: higher efficiency of therapy. 2 dwg
Patent RU-2183540-C1 (RU)
Title: Set with rotary faceplate for diffusion welding in vacuum
Inventor: ADEN V G
IPC: B23K20/26
Filed: 2001-06-05
Granted: 2002-06-20
Abstract: FIELD: mechanical engineering; welding facilities. SUBSTANCE: invention relates to sets furnished with devices for loading group of blanks into working chamber and welding the blanks at one evacuation step in working chamber. Improved uniformity of blank heating and reduced weight of faceplate and its turning forces are provided by installing faceplate manual turning lever under chamber, lever being mechanically coupled with faceplate shaft. Heater is rigidly secured on side wall of vacuum chamber at height exceeding possible height of blanks to be welded installed on faceplate. Stop is mounted over heater on one axle with heater. Power rod is arranged under faceplate provided with holes for passing of power rod and arrangement of blanks. Axes of holes are alternately aligned with power rod axis at turning of faceplate through preset angle. Power rod drive can be mechanical or hydraulic. Stop is installed on piston of hydraulic cylinder provided with pressure gauge brought out of chamber. EFFECT: improved heating of blanks, reduced weight of faceplate and its turning forces. 9 cl, 2 dwg
Patent RU-2188159-C1 (RU)
Inventor: GRINBERG E E
IPC: C01D15/00
Filed: 2001-06-14
Granted: 2002-08-27
Abstract: FIELD: inorganic compounds technology. SUBSTANCE: lithium hydroxide and niobium oxide are ground to particle size less than 1 mcm. Mixture is dehydrated and heated in oxygen-containing gas flow (70-100 vol.% oxygen and 0.01-0.05 wt. % moisture) to 850- 900 C at heating rate 1-20 C/min, preferably 4-10 C/min. Product is suited to application in electronic engineering. EFFECT: reduced power consumption and increased yield of single-phase powdered product. 5 cl, 1 tbl
Patent RU-2197879-C1 (RU)
Inventor: PLOTKIN A L
IPC: A41B9/02
Filed: 2001-10-23
Granted: 2003-02-10
Abstract: FIELD: light industry. SUBSTANCE: man's underwear has belt retainer and outer parts extending from belt retainer. Each outer part is terminated with part retained on leg region. Length of each outer part is selected so that the latter is positioned below knee region in the vicinity of calf, in particular, above or near upper part of calf, when underwear is put on. EFFECT: reduced usage of material and wider consumer properties. 7 cl, 1 dwg
Patent RU-2205946-C1 (RU)
Title: Method of development of oil pool
Inventor: SHARIFULLIN F A
IPC: C09K8/90
Filed: 2001-10-31
Granted: 2003-06-10
Abstract: FIELD: oil producing industry; applicable in development of oil formations by waterflooding. SUBSTANCE: method includes displacement of oil by fringe formed by successive injection into formation through injection wells of aqueous suspension based on mixture of bentonite clay and polyacrylamide and reagent, pushing it over formation by displacing fluid. Reagent is used in form of aqueous suspension based on mixture of wood flour, condensed spent sulfite-alcohol liquor and potassium bichromate. Added to aqueous suspension based on mixture of bentonite clay and polyacrylamide may be chromium acetate or bichromate of potassium or sodium. Pushing may be effected after injection of each suspension. In a variety of cases, operations of injection and pushing are repeated. EFFECT: increased coverage by waterflooding for long period of time, involving into active development of slightly drained or nondrained oil reserves, and increased oil mobility due to reduction of its viscosity. 4 cl, 1 tbl
Patent RU-2216597-C1 (RU)
Title: Method for start blowing of blast furnace
Inventor: INOZEMTSEV N S
IPC: C21B3/00
Filed: 2002-04-19
Granted: 2003-11-20
Abstract: FIELD: ferrous metallurgy, particularly blast furnace processes. SUBSTANCE: method comprises steps of loading in blast furnace blow-in charge; controlling height of arranging in furnace first batches of charge; supplying hot blowing air in mode providing operation of blast furnace during starting up period; before supplying hot blowing air through air tuyeres blowing to furnace inert gas heated until temperature no more than 1300C in such a way that 20 - 30% of blown inert gas is discharged out of blast furnace through gas discharging tubes inserted into iron taphole or through ports in hearth lining for iron tapholes; going on such processes until temperature of gas in mouth of furnace achieves 250 - 300 C; then feeding into furnace hot blowing air with parameters of start blasting process. EFFECT: increased service life period of blast furnace. 1 tbl
Patent RU-2217920-C1 (RU)
Inventor: KVASENKOV O I
IPC: A23L11/00
Filed: 2002-06-06
Granted: 2003-12-10
Abstract: FIELD: canned food industry. SUBSTANCE: method involves using smooth pea grains in biological maturity stage; subjecting pea grains to swelling; providing liquid media comprising preparation produced from Mortierella nigrescens micromycet biomass by predetermined process. EFFECT: provision for year-round reprocessing of pea grains into canned food and increased yield of canned food. 3 cl
Patent RU-2227594-C1 (RU)
Inventor: KVASENKOV O I
IPC: A23L21/10
Filed: 2002-09-26
Granted: 2004-04-27
Abstract: FIELD: confectionery industry. SUBSTANCE: method involves preparing syrup with the use of sugar, pectin and aqueous extract of mixture of thyme, leaves of brandy mint and leaves of garden balm; adding citric acid, sodium lactate and specific preparation into resultant mass during dressing procedure, said preparation being produced from Mortierella globulifera micromycet biomass obtained by predetermined process; pouring mass, forming, drying and packaging ready products. EFFECT: wider range of vitamin activity and unique combination of organoleptical properties of jelly marmalade. 1 ex
Patent RU-2227758-C1 (RU)
Title: Gas scrubbing unit
Inventor: STREL NIKOV N V
IPC: B01D47/02
Filed: 2002-10-30
Granted: 2004-04-27
Abstract: FIELD: metallurgy; cleaning gases from dust discharged from electric steel melting and iron melting surfaces and shot blast units. SUBSTANCE: proposed gas scrubbing unit has reservoir with partitions; one partition is provided with slots and other partition is provided with guide baffle; gas scrubbing unit is also provided with inclined drip pan, inlet and outlet branch pipes; reservoir is provided with distributing pipes with longitudinal slots which are located on ends of upper partitions on opposite side of baffle and additional partitions are mounted in parallel relative to main partitions. Inclined drip pan is secured to baffle at one end and to side surface of reservoir at other end. Inlet branch pipe located in upper part of reservoir is made in form of nozzle. Distributing pipes are detachable. EFFECT: complete use of cleaning zones; possibility of scrubbing fine fractions; enhanced ecological safety; continuity of process. 2 cl, 3 dwg
Patent RU-2229895-C1 (RU)
Inventor: SHEVCHENKO A A
IPC: A61K39/125
Filed: 2002-11-18
Granted: 2004-06-10
Abstract: FIELD: veterinary medicine. SUBSTANCE: the suggested vaccine contains as an antigen a 10-15%-hepatic suspension of rabbits died after infection by virulent viral strain of viral hemorrhagic disease in rabbits isolated out of local epizootic focus upon physiological solution (pH 7.2), theotropin, alumopotash alum at the following ratio of components, weight%: rabbits' hepatic suspension 98.1-98.6, theotropin 0.3-0.4, alumopotash alum 1.0-1.5. The suggested vaccine is of high immunogenicity and safe. EFFECT: higher efficiency. 5 ex, 1 tbl
Patent RU-2231410-C1 (RU)
Inventor: TAMIMI M M
IPC: B21D5/10
Filed: 2003-01-21
Granted: 2004-06-27
Abstract: FIELD: plastic metal working, possibly manufacture of elongated tubular shells of sheet material. 
     SUBSTANCE: method comprises steps of bending of sheet blank and discharging ready shape; bending sheet blank successively according to marks applied onto sheet blank symmetrically relative to symmetry line of sheet blank; making last bending along symmetry line of sheet blank; lifting ready shape by means of punch over die and moving it along lengthwise axis of punch. Sheet blank may be in the form of developed lateral surface of truncated cone. 
     EFFECT: possibility for making elongated thick-wall shapes with predetermined diameter in the form of cylinder, truncated cone and truncated pyramid, enhanced strength, enlarged using range of products. 
     1 dwg