baber/WOPTO huggingface dataset:
Patent CA-2552087-C (CA)
Inventor: BROWN KEVIN
IPC: C07D257/04
Filed: 2005-01-31
Granted: 2011-01-25
Abstract: Methods, composition, and intermediates are disclosed that are useful for making 4-Tetrazolyl-4-phenylpiperidine Compounds according to Formula (I), where Ar1 is -C3-C8 cycloalkyl, phenyl, naphthyl, anthryl, phenanthryl or -(5-7-membered) heteroaryl, each being unsubstituted or substituted with one or more R2 groups; Ar2 is phenyl, naphthyl, anthryl, phenanthryl or -(5-7-membered) heteroaryl, each being unsubstituted or substituted with one or more R2 groups; Z1 and Z2 are each independently a -(C1-C4 alkyl) group; R1 is -(CH2)nC(O)N(R3)(R4) where R3 and R4 are each independently H or -(C1-C4 alkyl); R2 is halogen, -C1-C3 alkyl, -O-(C1-C3 alkyl), -NH(C1-C3 alkyl) or -N(C1-C3 alkyl)2; n is an integer ranging from 1 to 4; m is an integer ranging from 0 to 4; and, in certain embodiments, the phenyl moiety attached to the 4-position of the piperidine ring of a compound according to Formula (I) can be optionally substituted with one or mor R2 groups.
Patent CA-2559566-C (CA)
Title: Pan spray formulation and delivery system
Inventor: PAUL LEONARD
IPC: A23B4/00
Filed: 2005-03-22
Granted: 2012-12-18
Abstract: By combining lecithin and oil as the principal ingredients, a highly effective, uniform, widely dispersed, pan release spray product is achieved with the lecithin comprising a de-oiled powdered lecithin. The de-oiled , powdered lecithin is blended with the vegetable oil to form a stable emulsion that exhibits superior pan release properties. Furthermore, the oil and lecithin emulsion of the present invention is easily formulated with a variety of blending agents to make flavorful salad dressings, marinades, and pet flavor enhancing products, as a non-aerosol, finger pump based product or as an aerosol product.
Patent CA-2564539-C (CA)
Inventor: BEELE WOLFRAM
IPC: C10M169/04
Filed: 2006-10-18
Granted: 2014-05-06
Abstract: A method for the coating of a base body is proposed, in which a layer of a platinum modified aluminide of the kind PtMAl is produced on the base body wherein M designates the metals iron (Fe) or nickel (Ni) or cobalt (Co) or combinations of these metals, wherein the layer is produced by means of a physical deposition out of the gas phase (PVD), wherein at least the two components aluminium (Al) and metal M are physically deposited out of the vapour phase, with the deposition being carried out at a process pressure of at least 0.1 mbar, preferably of at least 0.4 mbar and especially between 0.4 mbar and 0.6 mbar. A workpiece is further proposed, in particular a turbine blade, with a base body on which a layer is applied which is produced using a method of this kind.
Patent CA-2568167-C (CA)
Title: Ultra-expansion four-stroke internal combustion engine
Inventor: YANG ZENGLI
IPC: F02B41/00
Filed: 2005-05-20
Granted: 2010-08-31
Abstract: The invention discloses an internal combustion engine with super expansion.  The engine includes a cylinder (1) and a piston (2). When the piston arrives at the end point of the compression stroke, the compression pressure of intake volume achieving the requested power is in the range of 1.8Mpa to 5Mpa, thereby the combustion temperature and the combustion pressure are improved.  The working volume of the cylinder is designed by the super expansion rate depending on the effective pressure for working, wherein the working volume is larger than the intake volume. Making use of the heat energy of combustion gas produced in constant volume expansion stroke, the gas continues to expand in adiabatic condition to form the condition of super expansion work. A part of cooling water jacket is provided on the upper portion of the cylinder. Heat preservation means, but no cooling water jackets are provided on the lower portion of the cylinder, in order to avoid heat loss during the super expansion process. The decrease of the diameter of intake valve, the increase of the diameter of exhaust valve, and the reduction of the lead angle of exhaust can further enhance the effect of super expansion work. The invention can improve the heat efficiency notably, reduce the fuel consumption and pollution.
Patent CA-2570397-C (CA)
Inventor: MCDANIEL BENJAMIN D
IPC: A61M25/02
Filed: 2005-06-14
Granted: 2013-05-28
Abstract: A catheter grip adapted to couple with an introducer or sheath holds a catheter in position while in use in a patient's body. The grip has a hub defining a channel through which the catheter extends. The hub has a pair of grip members that work with each other to hold the catheter body between them, a pair of separators to release the catheter body, and a pair of tabs for the doctor to actuate the separators. Each pair of the grip members and the separators is situated on a different diameter of a surface that extends across the channel. Each grip member and separator is diametrically opposed to its mate and movement between the grip members are separators are coordinated in that as the grip members move toward each, the separators move away from each other, and vice versa.
Patent CA-2572532-C (CA)
Inventor: MANGALORE GEETHA
IPC: H04L12/16
Filed: 2006-12-28
Granted: 2013-09-17
Abstract: A method and apparatus are provided for enabling a Universal Plug and Play (UPnP) device to be automatically provisioned to access services without the need for manual interaction. In accordance with the invention, when a UPnP device needs to be provisioned, it automatically obtains pre-provisioning information from a provisioning device on the home network, and uses the pre-provisioning information to interact with the provisioning device to cause the UPnP device to be provisioned. The provisioning enables the UPnP device to access services, including digital rights management (DRM) services, over a network.
Patent CA-2574043-C (CA)
Inventor: KITCHEN WILLIAM J
IPC: B64D23/00
Filed: 2005-08-01
Granted: 2015-09-22
Abstract: A vertical wind tunnel flight simulator comprises a flight chamber wherein a flier may experience a freefall simulation. Airflow to support the flier is induced by fans connected above the flight chamber through a duct. A staging area having openings to the flight chamber is adjacent to the flight chamber. One or two return air ducts are used to return air from the fans outlet to the fans inlet. Opposed louvers are included on at least one duct segment thereby regulating the temperature via forcing ambient air into the simulator. The use of many duct segments having diverging walls adds commercial value to the system by lowering the height. Mounting components on the roof and behind walls creates a spectacular pedestrian viewing scene of people in flight.
Patent CA-2574929-C (CA)
Title: Bone morphogenetic protein (bmp)-17 and bmp-18 and compositions
Inventor: CELESTE ANTHONY J
IPC: C12P21/02
Filed: 1998-11-17
Granted: 2011-08-23
Abstract: Purified BMP-17 and BMP-18 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-17 and BMP-18 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, epithelium, brain, spleen, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.
Patent CA-2576110-C (CA)
Title: Polypeptides of botryosphaeria rhodina
Inventor: SCHNORR KIRK MATTHEW
IPC: C12N9/00
Filed: 2005-08-06
Granted: 2012-01-10
Abstract: The invention relates to functional polypeptides secreted from Botryospaeria rhodina CBS 247.96.
Patent CA-2576727-C (CA)
Inventor: DUBOIS LAURENT
IPC: C07D209/42
Filed: 2005-08-02
Granted: 2013-11-26
Abstract: The invention concerns compounds of general formula (I), wherein: X1, X2, X3, X4, Z1, Z2, Z3, Z4 and Z5 represent, independently of one another, a hydrogen or halogen atom, or a C1-C6-alkyl, C3-C7-cycloalkyl, C1-C6-fluoroalkyl, C1-C6-alkoxy, C1-C6-fluoroalkoxy, cyano, C(O)NR1R2, nitro, NR1R2, C1-C6-thioalkyl, -S(O)-C1-C6-alkyl, -S(O)2-C1-C6-alkyl, SO2NR1R2, NR3COR4, NR3SO2R5, or aryl group; X5 represents a hydrogen or halogen atom or a C1-C6-alkyl, C1-C6-fluoroalkyl group; R represents a 4-, 5-, 6- or 7-indolyl group optionally substituted; Y represents a hydrogen atom or a C1-C6-alkyl group; n is equal to 0, 1, 2 or 3; R1 and R2, represent, independently of each other a hydrogen atom or a C1-C6-alkyl, C3-C7-cycloalkyl, C3-C7-cycloalkyl-C1-C3-alkyl, or aryl group; or R1 and R2 together with the nitrogen atom bearing them form a azetidine, pyrrolidine, piperidine, azepine, morpholine, thiomorpholine, piperazine, homopiperazine group, said group being optionally substituted by C1-C6-alkyl, C3-C7-cycloalkyl, C3-C7-cycloalkyl-C1-C3-alkyl or aryl group; R3 and R4 represent, independently of each other, a hydrogen atom or a C1-C6-alkyl or aryl group; R5 represents a C1-C6-alkyl or aryl group; in base or acid addition salt, hydrate or solvate form. The invention also concerns a method for preparing said compounds and their therapeutic use.
Patent CA-2576910-C (CA)
Inventor: MUA JOHN-PAUL
IPC: A24C5/18
Filed: 2005-08-04
Granted: 2010-07-06
Abstract: A smoking article having one or more reconstituted tobacco split inner wrap strips is described. One or more split inner wrap strips extend coaxially along the tobacco column between the inner surface of an outer wrap of cigarette paper and the tobacco column. The tobacco blend includes burley and a second tobacco, such as flue-cured, oriental, Maryland, or rare and exotic tobaccos, and combinations thereof. This blend improves burley smoke character without increasing Hoffman analyte levels, especially tobacco-specific nitrosamines (i.e.,TNSAs). A cigarette with an improved burley smoke character without increasing Hoffman analyte levels is also described.
Patent CA-2578489-C (CA)
Title: Outil de nettoyage
Inventor: TSUCHIYA AKEMI
IPC: A47L13/17
Filed: 2005-08-10
Granted: 2009-12-29
Abstract: La présente invention décrit un dispositif de nettoyage à sec pour intérieurs incluant un matériau de base fibreux, qui est imprégné d'une préparation visant à réduire d'éventuelles propriétés antigéniques, d'un agent huileux et d'un surfactant. La préparation visant à réduire d'éventuelles propriétés antigéniques contient un composé réduisant les propriétés antigéniques de substances allergisantes, ce composé étant l'acide tannique. Le dispositif de nettoyage décrit dans la présente invention est susceptible de diminuer les propriétés antigéniques d'une substance allergisante en contact avec lui.
Patent CA-2580935-C (CA)
Title: Architecture d'antenne de sous-reseaux chevauchants
Inventor: LEWIS GIB F
IPC: H01Q21/06
Filed: 2006-01-17
Granted: 2013-04-02
Abstract: La présente invention concerne un ensemble d~antennes de réseau balayées électroniquement et comportant un réseau (100) d~éléments radiatifs (6) d~une hauteur de réseau (H). La pluralité de sous-réseaux (1-6) d~éléments radiatifs séparés comprend une première ligne composée d~une première pluralité de sous-réseaux dans laquelle les sous-réseaux ne se chevauchent pas horizontalement les uns avec les autres et une seconde ligne comprenant une seconde pluralité de sous-réseaux dans laquelle les sous-réseaux ne se chevauchent pas horizontalement les uns avec les autres. Les sous-réseaux de la seconde ligne sont disposés de manière contiguë, à la verticale des sous-réseaux de la première ligne. Les éléments radiatifs des sous-réseaux séparés ne sont partagés avec aucun autre sous-réseau. Les sous-réseaux des éléments radiatifs ont une hauteur inférieure à celle du réseau. Dans un autre élément, le procédé de suppression de la formation de lobes de périodicité dans une antenne de sous-réseaux de direction comprend l~application à un premier sous-réseau d~une première fonction d~éclairage et l~application à un second sous-réseau d~une seconde fonction d~éclairage. Dans ce procédé, la première fonction d~éclairage diffère de la seconde.
Patent CA-2587368-C (CA)
Title: Tape measure
Inventor: NIELSON ROB
IPC: G02B27/32
Filed: 2007-05-04
Granted: 2011-01-04
Abstract: A tape measure comprises a housing having a tape outlet opening. A flexible measuring tape is movable between a retracted position in which the measuring tape is substantially disposed within the housing, and an extended position in which at least a portion of the measuring tape extends through the tape outlet opening and linearly outside the housing. The measuring tape has a free end and a pair of longitudinal edges, and the measuring tape has measuring indicia displayed thereon. A magnifying lens is connected to the housing. The magnifying lens overlays the portion of the measuring tape extending outside the housing when the measuring tape is in the extended position. The magnifying lens extends laterally beyond one of the longitudinal edges of the measuring tape. A cross-hair extends across the magnifying lens. The cross-hair is generally perpendicular to the longitudinal edges of the portion of the measuring tape extending outside the housing. The cross-hair is aligned against the measuring indicia.
Patent CA-2591329-C (CA)
Inventor: DOYLE MARK C
IPC: A61M39/26
Filed: 2005-12-01
Granted: 2013-09-24
Abstract: A male Luer connector (200) that attaches to a female Luer connector to open a medical fluid flow channel between said connectors. The male connector has two internal valves (206, 208) and a vacuum-generating structure (212, 210). The two valves and the vacuum-~ generating structure are configured to draw back into the male connector any fluid residing on the interface between the connectors during their disengagement and to then seal the distal tip of the male connector. Both valves are opened/closed by a movable actuator plug (224) by contact with the front surface of the female connector. A resilient member (210) biases the male valves to the closed position and includes a variable internal volume (212) that creates the vacuum upon disengagement of the connectors. The male valves are timed to a particular sequence with the closing of an internal female connector valve so that the vacuum generated by the male connector will have the most fluid drawback effect.
Patent CA-2593642-C (CA)
Inventor: DZIEZOK PETER
IPC: A61F13/15
Filed: 2006-01-10
Granted: 2013-03-19
Abstract: The present invention relates to absorbent articles, such as diapers and sanitary nap-kins, and cores useful for such articles. More specifically, the invention relates to an absorbent article (20) having a longitudinal axis and a transverse axis, the absorbent article (20) comprising an absorbent core (28), the core (28) comprising a wearer fac-ing side oriented towards a wearer when the article (20) is being worn and an opposed garment facing side, the core (28) further comprising a storage layer (60), the storage layer (60) also comprising a wearer facing side and an opposed garment facing side, the absorbent article (20) further comprising a liquid pervious topsheet (24) on the wearer facing side of the core (28) and a liquid pervious backsheet (26) on the gar-ment facing side of the core (28), the core (28) further comprising a first core wrap sheet (56) covering the wearer facing side of the storage layer (60) and a second core wrap sheet (58) covering the garment facing side of the storage layer (60) the first core wrap sheet (56) being joined to the second core wrap sheet (58) along at least one stripe of juncture wherein either the stripe of juncture extends in the transversal direc-tion and the stripe of juncture provides a bond strength of at least 1 N/cm between the first core wrap sheet (56) and a second core wrap sheet (58) as measured as tensile strength in the longitudinal direction and comprises a microfiber adhesive or wherein the stripe of juncture extends in the longitudinal direction and comprises a microfiber adhesive.
Patent CA-2598351-C (CA)
Title: Protective gas for metal production
Inventor: HIBINO YASUO
IPC: B22D21/04
Filed: 2006-04-26
Granted: 2012-05-22
Abstract: Disclosed is a protective gas composition for preventing rapid oxidation or combustion of a molten magnesium/magnesium alloy. This protective gas composition is composed of a fluorine-containing organic compound and a carrier gas. Also disclosed is a method for preventing rapid oxidation or combustion of a molten magnesium or a magnesium alloy during production of magnesium or a magnesium alloy. This method is characterized in that the above-described gas composition is used as a protective gas for preventing rapid oxidation or combustion of a molten magnesium or a magnesium alloy.
Patent CA-2598518-C (CA)
Inventor: PALLE VENKATA P
IPC: C07D209/48
Filed: 2006-02-21
Granted: 2015-04-21
Abstract: The present invention relates to C ompounds having the structure of Formula I:    wherein n is an integer from 1 to 5; R1 is optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, heteroaryl, aralkyl, alkoxy, aryloxy, alkenyloxy or alkynyloxy; R2 is alkenyl, allcynyl, aryl, heterocyclyl, heteroaryl, cycloalkyl, NR4R5, -NHC(=Y)R4, -NHC(=Y)NR5R.chi., -NHC(=O)OR4, -NHSO2R4, C(=Y)NR4R5, C(=O)OR6 [wherein Y is oxygen or sulphur], ORS, -O(C=O)NR4R5, O-acyl, S(O)m R4, -SO2N(R4)2, cyano, amidino or guanidino [wherein R4 is alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, heteroaryl, aralkyl, heteroarylalkyl, heterocyclylalkyl or cycloalkylalkyl and m is an integer 0-2; R5 is hydrogen or R4; Rx is R4 or -SO2N(R4)2 and R6 is hydrogen, alkyl, cycloalkyl, aralkyl, heteroarylalkyl, heterocyclylalkyl or cycloalkylalkyl]; R3 is hydrogen, fluorine, alkyl, cycloalkylalkyl or aralkyl; A is OH, OR4, -OC(=O)NR4R5, O-acyl, NH2, NR4R5, NEC(=Y)R4, -NHC(=Y)NR5Rx, -NHC(=O)OR4, -NHSO2R4, and to processes for the synthesis of the same. This invention also relates to pharmacological compositions containing the compounds of the present invention, and methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by over expression and over-activation of an matrix metalloproteinase, using the compounds.
Patent CA-2598917-C (CA)
Inventor: ENRIGHT JEFFERY M
IPC: G07D11/22
Filed: 2004-03-09
Granted: 2013-06-18
Abstract: An automated banking machine includes a mechanism for accepting deposited items. Deposited items may be provided to the machine in envelopes which are first passed to a user from an envelope storage area (132) in the machine through a transport (124) and which are presented to the user through an opening (244). An envelope storage and dispensing device (134) is operative to assure that only a single envelope is delivered to the user. A user may thereafter include deposit items in the dispensed envelope. The deposited items are passed through the opening (244) and are deposited in a deposit-holding container (128). The deposited items may be marked with indicia corresponding to the transaction or properties of the deposited item where the envelope originally dispensed to the user for holding the deposited item.
Patent CA-2598995-C (CA)
Inventor: CONDON STEPHEN M
IPC: A61K31/551
Filed: 2006-02-27
Granted: 2014-07-15
Abstract: Molecular mimics of Smac are capable of modulating apoptosis through their interaction with cellular IAPs (inhibitor of apoptosis proteins). The mimetics are based on a monomer or dimer of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABLO, Hid, Grim and Reaper, which interact with a specific surface groove of IAP. The mimetics include those based on formula (IVa) and (IVb): (see formula IVa) (see formula IVb) Also disclosed are methods of using these peptidomimetics for therapeutic purposes. In various embodiments of the invention the Smac mimetics of the invention are combined with chemotherapeutic agents, including, but not limited to topoisomerase inhibitors, kinase inbhibitors, NSAIDs, taxanes and platinum containing compounds use broader language.
Patent CA-2604238-C (CA)
Inventor: ARLEN MYRON
IPC: C07H21/00
Filed: 2006-04-14
Granted: 2015-07-07
Abstract: The present invention provides for purified or highly pure recombinant monoclonal antibodies that bind to human colorectal and pancreatic carcinoma-associated antigens (CPAA), along with nucleic acid sequences encoding the antibody chains, and the amino acid sequences corresponding to said nucleic acids and uses for said sequences.
Patent CA-2606197-C (CA)
Inventor: BARRON WES
IPC: C04B41/53
Filed: 2005-08-26
Granted: 2010-08-10
Abstract: A method and an apparatus for laser marking indicia in the volume of gemstones such as diamonds, the indicia being made up of a plurality of microscopic dot-shaped marks whose build-up can be initiated by exposing naturally-occurring internal defects or impurities in the volume of a gemstone to a tightly focused train of laser pulses. Authentication data is encoded in the gemstone from the relative spatial arrangement of the dot-shaped marks that form the indicium. Taking advantage of the presence of otherwise invisible defects in the gemstone allows for inscribing indicia with laser pulses carrying energies substantially lower than the threshold energy required for inscribing in the volume of a perfect gemstone material. The marking process is then much less susceptible to inflict damages to the surface of the gemstone, and the marking can be performed using a broad variety of femtosecond laser systems. The dot-shaped marks engraved at a depth below the surface of a gemstone can be made undetectable with the unaided eye or with a loupe by limiting their individual size to a few micrometres, while devising indicia made up of only a few marks. As a result, the marking does not detract from the appearance and value of the gemstone. The procedure for laser marking accounts for the random spatial distribution of the defects present in natural gemstones as well as for their strongly localized character. The presence of an indicium can be detected by using a dedicated optical reader that can be afforded by every jewellery store.
Patent CA-2614985-C (CA)
Title: Train de roulement pour vehicules sur rails
Inventor: SOMMERER RUDOLF
IPC: B61F5/38
Filed: 2006-07-10
Granted: 2013-12-31
Abstract: L'invention concerne un train de roulement (20) destiné à des véhicules sur rails (1) et comprenant au moins trois essieux (3, 3') montés dans un châssis de bogie ainsi qu'au moins un dispositif directeur (4) permettant un déplacement transversal d'un essieu d'extrémité. Selon l'invention, le châssis de bogie (2, 2') présente, en sens longitudinal, plusieurs sections (A, B) dont au moins la première (A) dans le sens de la marche, dans laquelle est placé l'essieu avant (3'), est reliée à une deuxième section rigide (B) de manière à pouvoir pivoter horizontalement.
Patent CA-2616642-C (CA)
Title: Pneumatically actuated infrared welding method and apparatus
Inventor: BEUTE SCOTT M
IPC: B29C65/16
Filed: 2007-12-24
Granted: 2013-12-17
Abstract: An infrared light source focuses infrared energy onto a work surface through the open end of a concentrator. The open end of the concentrator includes an elastomeric seal for sealably coupling the end of the concentrator directly to a work piece. Pneumatic pressure is applied through the concentrator and the seal to urge the work pieces together during the heating process to complete the weld. The method of infrared (IR) welding includes the steps of applying concentrated IR energy to at least one thermoplastic member while simultaneously applying pneumatic pressure to the work pieces for welding one member to another.