baber/WOPTO huggingface dataset:
Patent DE-69330131-D1 (DE)
Inventor: KRAPCHO PAUL
IPC: A61K31/437
Filed: 1993-09-08
Granted: 2001-05-17
Abstract: Compounds of formula (I) wherein R is hydrogen or hydroxy; one of X and Y is a carbon atom and the other is a nitrogen atom, with the proviso that when Y is nitrogen, R is hydrogen; A and B are the same or different and are selected from the group of C1-C10 alkyl or phenylalkyl; C2-C10 alkyl having one or two substituents selected from the group consisting of OR1 and NR2R3; C2-C10 alkyl interrupted by one or two oxygen atoms or by one -NR4- group, and being said C2-C10 alkyl optionally substituted by one or two hydroxy (OH) or NR2R3 groups; R1 is selected from the group consisting of hydrogen, C1-C6 alkyl, phenyl, phenylalkyl, -S(O2)R5, C2-C6 alkyl optionally substituted by NR2R3; R2 and R3 may be the same or different and are selected from the group consisting of hydrogen, C1-C10 alkyl, phenylalkyl, phenyl, C2-C10 alkyl substituted with one or two hydroxy (OH) groups, or R2 and R3 taken together with the nitrogen atom to which they are attached form an ethyleneimine ring or a 5- or 6-member aromatic or non-aromatic heterocyclic ring which optionally contains another heteroatom such as sulfur, oxygen or nitrogen; R4 is selected from the group consisting of hydrogen, C1-C10 alkyl, C2-C10 hydroxylalkyl, C2-C10 alkyl substituted by NR2R3, phenylalkyl, phenyl; R5 is selected from the group consisting of C1-C10 alkyl, phenylalkyl; as free bases and their salts with pharmaceutically acceptable acids. These compounds have been shown to have antitumor activity.
Patent DE-69333808-D1 (DE)
Inventor: OHNO TSUNEYA
IPC: C12Q1/68
Filed: 1993-10-25
Granted: 2005-06-16
Abstract: The invention provides a probe useful for rapidly detecting and identifying fungi causative of infectious diseases by digesting completely a DNA extracted from a fungus Candidat albicans with EcoRI, inserting the same into an appropriate cloning vector, and picking up a probe containing DNA fragments unique to each fungus. The invention also provides a standard sequence suitable for making reference to a genomic DNA contained in a clinical specimen by elucidating the base sequence of the probe thus picked up. <IMAGE>
Patent DE-69406670-D1 (DE)
Inventor: FRAU PAOLA
IPC: G07F9/02
Filed: 1994-08-01
Granted: 1997-12-11
Abstract: PCT No. PCT/EP94/02549 Sec. 371 Date Jan. 30, 1996 Sec. 102(e) Date Jan. 30, 1996 PCT Filed Aug. 1, 1994 PCT Pub. No. WO95/04333 PCT Pub. Date Feb. 9, 1995The invention is a distribution network system of automatic dispensers of products and information interconnected with one another and with at least a host computer, where homogeneous groups of dispensers are suitable for exchanging information, by means of said host computer, with each dispenser connected with it and with the network node that is connected with each host computer by means of telephone lines and is provided with a transceiver section suitable for getting through to each dispenser by radio, through an antenna or a communication satellite.
Patent DE-69408145-D1 (DE)
Inventor: POLLAK ALFRED
IPC: A61K51/08
Filed: 1994-07-18
Granted: 1998-02-26
Abstract: Radionuclide chelating compounds are provided for conjugation to targeting molecules such as proteins, peptides or antibodies. The resulting labeled targeting molecules may be used in diagnosis and therapy.
Patent DE-69421188-D1 (DE)
Inventor: TORGERSON PETER
IPC: A61K8/90
Filed: 1994-08-09
Granted: 1999-11-18
Abstract: The present invention relates to water or alcohol soluble or dispersible silicone grafted thermoplastic elastomeric copolymers and to cosmetic and pharmaceutical compositions containing these copolymers. This invention especially relates to copolymers useful for hair styling purposes, and to hair styling compositions containing these copolymers. This invention further relates to copolymers useful for providing cosmetic and pharmaceutical compositions for topical application to the skin. These topical skin care compositions are useful for delivering and/or transdermally transporting active ingredients to or thorugh the skin.
Patent DE-69428132-D1 (DE)
Inventor: KNAPP R
IPC: A61L27/50
Filed: 1994-11-04
Granted: 2001-10-04
Abstract: A filler material for a surgically implantable prosthesis comprised of a synthetic triglyceride having a viscosity substantially greater than that of naturally occurring triglycerides is provided. The triglyceride composition is formed of saturated alkyl chains to reduce or limit the potential for oxidation of the alkyl chains to form peroxide groups which adversely affect the biocompatibility of the filler material and the implant. Preferably, the filler material has a viscosity substantially the equivalent of a normal human breast. The synthetic triglyceride filler material may also have a lower viscosity which is a liquid at room temperature for use in inflatable devices. Prostheses containing filler material having the desired viscosity and antioxidation characteristics are also provided as well as a method for preparing the filler material.
Patent DE-69429510-D1 (DE)
Inventor: ERIKSSON LENNART
IPC: G07C1/00
Filed: 1994-03-30
Granted: 2002-01-31
Abstract: PCT No. PCT/SE94/00295 Sec. 371 Date Sep. 27, 1995 Sec. 102(e) Date Sep. 27, 1995 PCT Filed Mar. 30, 1994 PCT Pub. No. WO94/23410 PCT Pub. Date Oct. 13, 1994A sealing method by means of which breaking of a seal is detected at least subsequently. The method is mainly characterized by recording breaking of the seal in a readable manner with the aid of an updatable information carrier (2). The invention also relates to a sealing arrangement.
Patent DE-69433610-D1 (DE)
Inventor: BONVALLAT PIERRE
IPC: H04M1/02
Filed: 1994-06-15
Granted: 2004-04-22
Abstract: The interconnection terminal has distributor lines connected in a non accessible compartment, and subscriber connections in a second accessible compartment. The connections (29) between the first and second compartment does not use wires.
Patent DE-69434924-D1 (DE)
Inventor: WOLLOWITZ SUSAN
IPC: C07D493/04
Filed: 1994-06-24
Granted: 2007-03-29
Abstract: Psoralen compounds are synthesized which have substitutions on the 4, 4', 5' and 8 positions of the psoralen, which permit enhanced binding to nucleic acid of pathogens.  Higher psoralen binding levels and lower mutagenicity are described, resulting in safer, more efficient, and reliable inactivation of pathogens in blood products. The invention contemplates inactivation methods using the new psoralens which do not compromise the function of blood products for transfusion.
Patent DE-69512419-D1 (DE)
Inventor: ALOUP JEAN-CLAUDE
IPC: A61K31/495
Filed: 1995-07-17
Granted: 1999-10-28
Abstract: PCT No. PCT/FR95/00951 Sec. 371 Date Jan. 17, 1997 Sec. 102(e) Date Jan. 17, 1997 PCT Filed Jul. 17, 1995 PCT Pub. No. WO96/02544 PCT Pub. Date Feb. 1, 1996A compound of formula (I):    <IMAGE>  (I)  wherein R, R1, R2, and R3 are as defined in the application, salts thereof, preparation thereof and drugs containing same.
Patent DE-69514034-D1 (DE)
Inventor: GUITONEAU HANS
IPC: F16L55/124
Filed: 1995-04-12
Granted: 2000-01-27
Abstract: The shut-off consists of an inflatable balloon (4) which is equipped with an asymmetrical element (6) opposite its opening to deploy it inside the pipe. The element can be connected to the end of a flexible rod (10) which passes through the middle of the balloon. The balloon can be inserted through a branch (2) fixed to the pipe at right angles, designed to receive a movable tube (15) with a hollow bar (9) inside it for inflating the balloon. The tube has an outer diameter which is slightly smaller than the inner diameter of the branch, and there is a seal (14) between the tube and the hollow bar. During operation the asymmetrical element interacts with the inner surface of the pipe when inserted, and takes the balloon to one side of the insertion point, where it can be inflated. <IMAGE>
Patent DE-69520429-D1 (DE)
Inventor: LEW CHEL W
IPC: A01N57/12
Filed: 1995-07-27
Granted: 2001-04-26
Abstract: The present invention relates to encapsulation of agriculturally active ingredients (AIs). Suitable AIs for encapsulation are selected from carbamates, organophosphates, compounds which break down an insect's digestive tract tissue, nicotine, rotenone, neem oil or azadiractin, natural or synthetic pyrethrins, petroleum oils, halogenated hydrocarbons, Bacillus thuringiensis, and insecticidal viruses. The binder is an emulsifier for said agriculturally effective active ingredient, exhibits a stable solid form at 20 DEG C, and exhibits a melting point within the range of about 40 DEG to about 100 DEG  C.
Patent DE-69530533-D1 (DE)
Inventor: BARAVIAN JEAN
IPC: E04D5/02
Filed: 1995-02-08
Granted: 2003-06-05
Abstract: Prodn. of two layer textile reinforcement for bituminous roof sealing coating consists of taking a non-woven layer and consolidating it by mechanical binding or hydraulic binding e.g. by water jet; then thermostabilising at 180-240, pref. 200-220 degrees C for 5-60, pref. 8-20 secs.. That layer is then assembled with a second mineral fibre, esp. glass fibre, layer by bonding, sewing or knitting. The last two methods are only used when the second layer is a fabric or a mesh. The adhesive for bonding is a thermoplastic or hot-set polymer e.g. polyester, polyamide, polyurethane or EVA, with m.pt. of 160-220 pref. 190-200 degrees C.
Patent DE-69534671-D1 (DE)
Inventor: LEVY J
IPC: A61F2/24
Filed: 1995-10-20
Granted: 2006-01-12
Abstract: Naturally-derived bioprosthetic materials are treated with epoxide crosslinking agents. In some embodiments, the tissue is crosslinked with low molecular weight epoxides in aqueous solutions at high pH levels. In other embodiments, the tissue is crosslinked at physiologic pH levels with epoxide crosslinking agents catalyzed with tertiary or quaternary amines, such as Tris or imidazole. In an advantageous embodiment, bioprosthetic tissue is crosslinked and derivatized with an anticalcification agent, such as a polyphosphonate anticalcification agent, using a polyphosphonate:polyepoxide monoadduct.
Patent DE-69624006-D1 (DE)
Inventor: MORONI UGO
IPC: A47J31/30
Filed: 1996-12-09
Granted: 2002-10-31
Abstract: A coffee maker (10) provides a boiler (11), a coffee vessel (15) and a collecting vessel (12); the water heated in a boiler (11) passes through the coffee vessel (15) containing coffee powder and the coffee infusion obtained flows into the collecting vessel (12); the path between the boiler (11) and the collecting vessel (12) is closed off by valve means (22,23,23A) and is opened up once a predetermined overpressure with respect to atmospheric pressure is attained in the boiler (11); the water/air volumetric ratio in the boiler (11) does not exceed 1:2. The coffee produced may be similar to that prepared using espresso coffee machines.
Patent DE-69712888-D1 (DE)
Inventor: MIYAMOTO MASAOMI
IPC: A61K31/122
Filed: 1997-07-10
Granted: 2002-07-04
Abstract: A compound of the formula:wherein R1 represents a lower alkyl; R2 represents H, an optionally substituted alkyl or an optionally substituted alkenyl; R3 and R4 each represents an optionally substituted lower alkyl or a lower alkoxy, or R3 and R4 form, taken together, an optionally substituted butadienylene; and X1 and X2 each represents an optionally esterified or etherified hydroxy, or a salt thereof is useful for protecting cells from the cytotoxicity of beta-amyloid protein.
Patent DE-69717046-D1 (DE)
Inventor: MERLE JEAN-PIERRE
IPC: G01S3/784
Filed: 1997-09-09
Granted: 2002-12-19
Abstract: The photosensitive detector (3) detects incoming laser light pulses (2). The pulses are converted to electrical energy. The energy is processed by a differential amplifier processor (4), which is colocated with the photsensitive detector. The differential amplifier reinforces signals with a rapid rise time produced by the laser pulses, and attenuates the slowly varying noise intensity signals produced by the photsensitive diode.
Patent DE-69719211-D1 (DE)
Inventor: CUIF PIERRE
IPC: C01F7/00
Filed: 1997-10-09
Granted: 2003-03-27
Abstract: Mixed oxides of cerium and zirconium as well as solid solutions and cerium oxides are produced having improved thermal stability. The process involves the formation of cerium and zirconium oxides, mixed oxides and solid solutions by methods such as co-thermohydrolysis and co-precipitation, followed by washing or impregnating with an alkoxylated compound having greater than (2) carbon atoms. After the washing or impregnating step, the mixture is calcined to form oxides having very high surface area and oxygen storage capacity. The improved thermal stability of the oxides makes them advantageous for use in applications such as catalytic converters.
Patent DE-69724778-D1 (DE)
Inventor: HAMMOND PAUL STEPHEN
IPC: G01N29/34
Filed: 1997-04-21
Granted: 2003-10-16
Abstract: PCT No. PCT/GB97/01095 Sec. 371 Date Dec. 10, 1998 Sec. 102(e) Date Dec. 10, 1998 PCT Filed Apr. 21, 1997 PCT Pub. No. WO97/40375 PCT Pub. Date Oct. 30, 1997An energy meter for measuring parameters of fuel gas. The meter has a gas inlet and outlet and a central tube along which the gas flows from inlet to outlet. Ultra-sound transducers and a control form a system whereby the speed of ultra-sound signals traveling through the gas between the transducers is measured and used in the control to calculate the volume of gas which is passed through the meter. The ultra-sound signals pass through apertures in the walls of chambers containing the transducers. Another ultra-sound transducer in the chamber which is connected to the control acts as an emitter and receiver of ultra-sound signals reflected by reflectors. These signals travel through the fuel gas in the chamber and their attenuation is observed and measured by the control when they are received by the transducer. The measured attenuation is used to derive the calorific value and/or Wobbe index of the gas. The control uses the volume of gas and the calorific value and/or Wobbe index to derive the amount of energy in the gas.
Patent DE-69731943-D1 (DE)
Inventor: CAVICCHIOLI GIOVANNI
IPC: A61M1/16
Filed: 1997-10-17
Granted: 2005-01-20
Abstract: The method allows determination of the re-circulation of blood in a vascular access (11) of a patient whose blood is being subject to treatment (12) in an extra-corporal circuit. The process includes regulating the flow rate of blood in the extra-corporal circuit and a predetermined value (QB), and determining a first value (HGBA0) of the parameter representing the concentration of blood in the extra-corporal circuit. A variation in the amplitude (QUF) of the ultra-filtration flow rate in the treatment appts. (12) is effected. A second value (HGBA3) of the concentration parameter is then determined. The re-circulation (AR) of the blood in the extra-corporal circuit is determined on the basis of the blood flow rate (QB), the ultra-filtration flow rate amplitude (QUF) and the two parametric flow rate measurements.
Patent DE-69733618-D1 (DE)
Inventor: GRISSOM B
IPC: A61K48/00
Filed: 1997-08-22
Granted: 2005-07-28
Abstract: The present invention relates to bioconjugates and the delivery of bioactive agents which are preferably targeted for site-specific release in cells, tissues or organs. More particularly, this invention relates to bioconjugates which comprise a bioactive agent and an organocobalt complex. The bioactive agent is covalently bonded directly or indirectly to the cobalt atom of the organocobalt complex. The bioactive agent is released from the bioconjugate by the cleavage of the covalent bond between the bioactive agent and the cobalt atom in the organocobalt complex. The cleavage may occur as a result of normal displacement by cellular nucleophiles or enzymatic action, but is preferably caused to occur selectively as a predetermined release site by application of an external signal. The external signal may be light or photoexcitation, i.e. photolysis, or it may be ultrasound, i.e. sonolysis. Further, if the photolysis takes place in the presence of a magnetic field surrounding the release site, the release of the bioactive agent into surrounding healthy tissue is minimized.
Patent DE-69801446-D1 (DE)
Inventor: METHLOUTI MOUNJI
IPC: G06K19/00
Filed: 1998-04-03
Granted: 2001-09-27
Abstract: The integrated circuit card (1) proposed by the invention is intended to facilitate the calculation of bonus points by having the card reader send the card an identity (I1) during a transaction. This identity allows the card to recognize (12) the type of service supplier or vendor in each case, and to implement a set of rules unique (5, 11) to this supplier or vendor or, in the absence of such rules, to use standard rules set by the issuer of the card. These rules calculate the bonus points specific to the supplier in question. The bonus points are then cumulated in a counter also reserved exclusively for the same supplier.
Patent DE-69806598-D1 (DE)
Inventor: WILCZYNSKI PAWEL
IPC: G01F15/00
Filed: 1998-05-05
Granted: 2002-08-22
Abstract: A credit transfer system is provided for transferring credit, representing credited consumption of a metered service G issued to a consumer, to a consumer metering apparatus (1, 2) which is selectively operable to cut-off the supply of the service to the consumer. The system comprises payment means (2) for controlling supply of the metered service G by the consumer metering apparatus in dependence on received credit. The payment means (2) has a memory for storing received credit data indicative of the total of all credit ever received by the payment means. The system includes a portable data storage device (3), associated with the payment means (2), for storing issued credit data indicative of the total of all credit ever issued for the payment means (2). The system also includes means for verifying the association of the data storage device (3) and payment means (2). The payment means (2) is operative to read the issued credit data from the associated data storage device (3) and, if the association is verified, to determine from the issued credit data and said received credit data the amount of any newly issued credit, and to update said received credit data in accordance with the newly issued credit so determined.
Patent DE-69816815-D1 (DE)
Inventor: VAN GANSBERGHE FREDERIC
IPC: C07C51/44
Filed: 1998-06-05
Granted: 2003-09-04
Abstract: The invention concerns a method for recuperating and purifying a lactic acid solution obtained initially from a fermentation medium or any other source, consisting in a pre-treatment to eliminate the ion loads capable of catalysing the lactic acid condensation and based on the principle of ion exchange or any other related principle, followed by at least a step of concentration at low temperature and brief retention time and at least a step of distilling the lactic acid using a thin layer process.
Patent DE-69816842-D1 (DE)
Inventor: RIDDLE L
IPC: C01B21/20
Filed: 1998-05-21
Granted: 2003-09-04
Abstract: The invention provides a method for purification of hydroxylamine so as to have a substantial reduction of cations and anions. The method involves passing a solution of hydroxylamine through at least one strong acid ion exchange bed which has been pretreated with dilute hydrochloric acid and then through at least one strong base anion exchange resin bed.
Patent DE-69817284-D1 (DE)
Inventor: TERWIEL ANDREAS JOHANNES GERHA
IPC: F26B25/06
Filed: 1998-08-31
Granted: 2003-09-25
Abstract: The invention relates to a support (1) for supporting ceramic products, in particular roofing tiles. The support (1) is built up of a framework consisting of interconnected longitudinal wires (12-15) and cross wires (6,7,10,11), to which supporting elements (29,32,33) for locally supporting the ceramic products during the drying process are attached. The support is thereby provided on each of its sides with two wires which are disposed one above the other. <IMAGE>
Patent DE-69823945-D1 (DE)
Inventor: GITTOES EDWIN ARTHUR
IPC: F25B49/02
Filed: 1998-10-02
Granted: 2004-06-24
Abstract: A terminal box (2) for a refrigeration compressor (4) of refrigeration apparatus (6), comprising control means (10) for automatically controlling the operation of the refrigeration compressor (4), the control means (10) being a solid state control means which comprises first and second timers (16, 18). The first timer (16) is for providing an adjustable time delay for at least one oil pressure differential switch (20, 22) to control the period before the oil pressure differential switch (20, 22) is able to be re-set after operation whereby refrigerant which is mixed with oil is removed from the oil as refrigerant gas and the oil is then able to provide optimum lubrication for a motor (19) of the refrigeration compressor. The second timer (18) is for controlling the starting of the motor (19). The motor (19) has windings and an armature, and the second timer ensures that during start up of the motor (19), the windings receive only part of the maximum available current until the armature is rotating sufficiently fast for the windings to receive the maximum available current without damage being caused to the motor (19). <IMAGE>
Patent DE-69824004-D1 (DE)
Inventor: WILLEY C
IPC: G01N35/10
Filed: 1998-06-15
Granted: 2004-06-24
Abstract: A method and apparatus for quantitative measurement of gene expression through multiplex competitive reverse transcriptase polymerase chain reaction amplification are disclosed. The method and apparatus are especially useful for analysis of small specimens of cells and tissues.
Patent DE-69827652-D1 (DE)
Inventor: SWAMINATHAN JAYARAMAN
IPC: A61M29/02
Filed: 1998-09-18
Granted: 2004-12-23
Abstract: A balloon catheter for use with a guidewire is disclosed. The catheter has a body with a balloon located thereon, preferably at the distal end. A lumen within the catheter body communicates with the interior of the balloon which can be inflated by known methods with saline solution. A series of sleeve members of predetermined lengths and sizes are coupled to and positioned along the length of the catheter body. One or more of the sleeve members can span the length of the balloon. Each sleeve member has a passageway and both an exit and entry port so that the guidewire can pass therethrough. Instead of a balloon, the catheter can include a device member that forms a chamber which can store medicine until discharged at the desired site within the blood vessel. Apertures or pores on the catheter body allow for the perfusion of blood or the delivery of medicine to the site of the blood vessel. A method of operation is also disclosed.
Patent DE-69841751-D1 (DE)
Title: Chemokin alpha-5
Inventor: WEI YING-FEI
IPC: C12N15/09
Filed: 1998-11-18
Granted: 2010-08-12
Abstract: The present invention relates to a novel CKalpha-5 protein which is a member of the alpha chemokine family. In particular, isolated nucleic acid molecules are provided encoding the human CKalpha-5 protein. CKalpha-5 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. Antibodies and fragments thereof that specifically bind to CKalpha-5 polypeptides are also disclosed, as are compositions and methods for making such antibodies. The invention further relates to screening methods for identifying agonists and antagonists of CKalpha-5 activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders.