baber/WOPTO huggingface dataset:
Patent CA-2897629-A1 (CA)
Inventor: DEMIN ALEXANDRE VIKTOROVICH
IPC: A61P35/00
Filed: 2014-01-15
Abstract: The invention relates to the field of medicine, and more particularly to oncology and immunology. Proposed are novel compounds of general formula (1) or (2), which have an affinity for CD16a. Proposed are novel modified proteins, active toward the CD16a receptor, which are selected from an antibody or an autoantigen and are conjugated by a modified compound selected from a compound of general formula (1) or (2), and which enhance and direct antibody-dependent cell cytotoxicity. The novel modified proteins (conjugates) can be used to destroy a specific target group of cells in an organism, such as cancer cells or autoimmune lymphocytes. Also proposed are methods for producing conjugates, and a pharmaceutical composition and a drug containing modified proteins for the treatment of cancer and autoimmune diseases.
Patent CA-2898890-A1 (CA)
Inventor: SUNILKUMAR T K
IPC: C07C403/24
Filed: 2014-01-23
Abstract: The present invention provides beta-cryptoxanthin crystals from plant source and a process for its preparation. The present invention particularly relates to a process for the preparation of high purity beta-cryptoxanthin crystals comprising at least about 10% by weight total xanthophylls, of which at least about 75% by weight is trans-beta-cryptoxanthin and the remaining including beta-carotene, and trace amounts of trans-capsanthin and other carotenoids derived from the plant source, including capsicum fruits. The production of beta-cryptoxanthin crystals with high content of trans-beta-cryptoxanthin makes it ideal and suitable for use as a provitamin A source material and also has potential effects on improving bone health and inhibiting bone resorption.
Patent CA-2899225-A1 (CA)
Inventor: BOY MATTHIAS
IPC: A23K10/38
Filed: 2008-07-04
Abstract: The present invention relates to a method for the production of an aqueous glucose solution from corn and/or corn grain. The invention also relates to a glucose solution obtained by this method, and the use thereof for the production of organic compounds.  The method according to the invention comprises: a) the fractionating dry milling of corn grains, wherein the corn grains are separated into an endosperm fraction containing corn starch and an oil-rich germ fraction, and optionally a bran fraction; b) enzymatic liquification and saccharification of the corn starch in an aqueous suspension of the endosperm fraction, wherein an aqueous glucose solution containing corn gluten is obtained; and c) concentration of the corn gluten and optionally, bran, from the aqueous glucose solution.
Patent CA-2900663-A1 (CA)
Inventor: DUSTERHOFT RONALD GLEN
IPC: E21B43/22
Filed: 2014-02-14
Abstract: In some aspects, an injection treatment of a subterranean region is controlled based on a target net treating pressure. A measure of fluid pressure acting on a subterranean region during an injection treatment is received. The measure of fluid pressure is compared against a target net treating pressure for fluid acting on the subterranean region during the injection treatment. The target net treating pressure is associated with a target fracture growth orientation. The injection treatment is modified based on a result of the comparison.
Patent CA-2900751-A1 (CA)
Title: Flow controller for use in drilling operations
Inventor: CHURCH RUSTY
IPC: E21B12/00
Filed: 2014-03-13
Abstract: A system (10) for drilling a borehole (14) in a subterranean formation (16) containing a fluid (18), comprising: an outer tube (24) defining an outer tube distal end (26) configured for attaching a drill bit (12) thereto and a flow controller receiving section (27) spaced apart therefrom; a flow controller (28) including a flow controller body (30) defining body proximal and distal ends (32 and 34) and securable to the outer tube (24) in the flow controller receiving section (27); and a drilling accessory (36) insertable in the outer tube (24) and through the flow controller (28). The flow controller (28) is movable between open and closed configurations. In the open configuration, the flow controller (28) allows passage of the drilling accessory (36) therethrough. In the closed configuration, the flow controller (28) hinders flow of the fluid therethrough towards the borehole proximal end (20) when the flow controller (28) is located closer to the borehole proximal end (20) than the fluid (18).
Patent CA-2903512-A1 (CA)
Inventor: BOUDREAULT RICHARD
IPC: C01F17/224
Filed: 2013-03-11
Abstract: There are provided processes for treating fly ash. For example, the processes can comprise leaching fly ash with HCI so as to obtain a leachate comprising aluminum ions and a solid, and separating the solid from the leachate; reacting the leachate with HCI so as to obtain a liquid and a precipitate comprising the aluminum ions in the form of AlCl3, and separating the precipitate from the liquid; and heating the precipitate under conditions effective for converting AlC13 into Al203 and optionally recovering gaseous HCI so-produced.
Patent CA-2907615-A1 (CA)
Title: Method of increasing fracture network complexity and conductivity
Inventor: CREWS JAMES B
IPC: C09K8/80
Filed: 2014-03-26
Abstract: A complex fracture network within a hydrocarbon-bearing subterranean formation is created by first pumping a first fluid into the formation to create or enlarge a primary fracture and then pumping a second fluid into the formation wherein the second fluid contains a viscous material and the first fluid. By diverting the flow of the second flow, a secondary fracture is created having a directional orientation distinct from the directional orientation of the primary fracture.
Patent CA-2911149-A1 (CA)
Title: Glycolipid inhibition using iminosugars
Inventor: LAING PETER
IPC: A61K31/445
Filed: 2014-04-30
Abstract: The application provides iminosugars with a high activity and specificity for inhibiting ceramide glucosyltransferase.
Patent CA-2914206-A1 (CA)
Title: Recycled hot asphalt mixture production method
Inventor: MORIYASU HIROCHIKA
IPC: C08K3/00
Filed: 2014-05-30
Abstract: Provided is a production method of a recycled hot asphalt mixture obtained by mixing a recycled aggregate, a new aggregate, asphalt, and an additive for recycle, comprising:  heating the additive for recycle; adding moisture to the heated additive for recycle and mixing thereof so as to make the additive for recycle be formed; and adding the additive for recycle in a foamed state to the recycled aggregate, the new aggregate, and the asphalt and mixing thereof.
Patent CA-2914638-A1 (CA)
Title: Rna-guided transcriptional regulation
Inventor: CHURCH GEORGE M
IPC: A61K48/00
Filed: 2014-06-04
Abstract: Methods of modulating expression of a target nucleic acid in a cell are provided including introducing into the cell a first foreign nucleic acid encoding one or more RNAs complementary to DNA, wherein the DNA includes the target nucleic acid, introducing into the cell a second foreign nucleic acid encoding a nuclease-null Cas9 protein that binds to the DNA and is guided by the one or more RNAs, introducing into the cell a third foreign nucleic acid encoding a transcriptional regulator protein or domain, wherein the one or more RNAs, the nuclease-null Cas9 protein, and the transcriptional regulator protein or domain are expressed, wherein the one or more RNAs, the nuclease-null Cas9 protein and the transcriptional regulator protein or domain co-localize to the DNA and wherein the transcriptional regulator protein or domain regulates expression of the target nucleic acid.
Patent CA-2919406-A1 (CA)
Title: Seat for a vehicle
Inventor: GIROUARD BRUNO
IPC: B60N2/39
Filed: 2014-07-24
Abstract: A vehicle has a body. A pivotable seat has a front portion pivotally connected to the body about a front pivot point and extending rearwardly therefrom to a back portion. A rear left leg is pivotally connected to the body about a left lower pivot point and to the back portion to about a left upper pivot point. A rear right leg is pivotally connected to the body about a right lower pivot point and to the back portion about a right upper pivot point. A distance between the lower pivot points is greater than a distance between the upper pivot points. The seat is pivotable relative to the body about an instantaneous seat pivot axis passing through the front pivot point, a left axis extending through the left upper and lower pivot points, and a right axis extending through the right upper and lower pivot points.
Patent CA-2920315-A1 (CA)
Title: Diphenyloxyalkylamine derivatives and aryloxyalkylamine derivatives, pharmaceutical composition, use of said pharmaceutical composition for treating, preventing or inhibiting chronic pulmonary inflammatory diseases and method for treating or preventing such diseases
Inventor: MARTINS MARCO AURELIO
IPC: A61P29/00
Filed: 2014-08-06
Abstract: The present invention relates to diphenyloxyalkylamine derivatives and aryloxyalkylamine derivatives that are structurally analogous to mexiletine, said derivatives having important biological activity and not causing the undesired side effects observed with the prototype, as well as with other drugs from the same therapeutic class as the prototype. The derivatives of the present invention have formulas II and III and are used for treating, preventing or inhibiting pulmonary inflammatory diseases, for example, asthma and chronic obstructive pulmonary disease (COPD).
Patent CA-2920750-A1 (CA)
Inventor: SCHOEN JERRY WILLIAM
IPC: C21D1/76
Filed: 2014-08-26
Abstract: Increasing the chromium content of an electrical steel substrate to a level greater than or equal to about 0.45 weight percent (wt%) produced a much improved forsterite coating having superior and more uniform coloration, thickness and adhesion. Moreover, the so-formed forsterite coating provides greater tension potentially reducing the relative importance of any secondary coating.
Patent CA-2920973-A1 (CA)
Inventor: ZHU XIAOCHUN
IPC: A24F40/60
Filed: 2016-01-26
Abstract: Certain aspects of present invention relate to a ceramic vaporizer for e-cigarette and e-cigarettes having ceramic vaporizer with replaceable e-liquid storage medium. In certain embodiments, ceramic vaporizer may include cylindrical vaporizer body, vaporizer heater, and replaceable e-liquid storage medium. Cylindrical vaporizer body has an interior surface, and an exterior surface. Interior surface forms a central vapor passage and exterior surface forms an inside wall of an e-liquid storage device. The vaporizer heater is embedded inside the cylindrical vaporizer body. The vaporizer heater may include one or more heating elements configured to heat e-liquid stored in e-liquid storage device and e-liquid is in direct contact with exterior surface of the cylindrical vaporizer body. The one or more heating elements may include certain electrothermal alloys. In certain embodiments, the one or more heating elements may include one or more mesh heating elements, and one or more spiral heating elements.
Patent CA-2921876-A1 (CA)
Title: Procede de production de polymeres en emulsion
Inventor: KEHRLOSSER DANIEL
IPC: C09D151/06
Filed: 2014-08-18
Abstract: L'invention concerne un procédé de production de particules de polymère en émulsion à structure coeur-écorce, le rapport pondéral des écorces étant compris dans des limites particulières, ainsi que leur utilisation dans les peintures, les produits de couchage pour le papier, les mousses et les produits cosmétiques.
Patent CA-2922994-A1 (CA)
Title: Procede base sur un serveur pour la recherche d'un point d'interruption d'un flux de donnees, et serveur
Inventor: YU CHUANSHUAI
IPC: G06F17/40
Filed: 2014-02-27
Abstract: La présente invention concerne, dans un mode de réalisation, un procédé basé sur un serveur pour la recherche d'un point d'interruption d'un flux de données. Dans le mode de réalisation de la présente invention, des points d'interruption du flux de données sont recherchés en déterminant si au moins une partie des données contenues dans une fenêtre parmi M fenêtres satisfait une condition prédéterminée. Si au moins une partie des données contenues dans une fenêtre ne satisfait pas la condition prédéterminée, N*U longueurs sont sautées et un point d'interruption potentiel suivant est obtenu. Le rendement de la recherche de points d'interruption d'un flux de données est amélioré.
Patent CA-2926418-A1 (CA)
Title: Methods for treating fibrotic cancers
Inventor: BRUHN SUZANNE
IPC: A61P35/00
Filed: 2014-10-08
Abstract: In part, the disclosure relates to methods of treating fibrotic cancers by administering one or more Serum Amyloid Protein (SAP) agonists. In certain aspects, the method further comprises the conjoint administration of an anti-cancer therapeutic, e.g., a chemotherapeutic agent. In certain aspects, the disclosure relates to methods of treating myelofibrosis by administering an SAP agonist and optionally one or more anti-cancer therapeutic agents.
Patent CA-2927096-A1 (CA)
Title: Unmanned aerial vehicle delivery system
Inventor: KIMCHI GUR
IPC: G01C21/36
Filed: 2014-09-30
Abstract: This disclosure describes an unmanned aerial vehicle ("UAV") configured to autonomously deliver items of inventory to various destinations. The UAV may receive inventory information and a destination location and autonomously retrieve the inventory from a location within a materials handling facility, compute a route from the materials handling facility to a destination and travel to the destination to deliver the inventory.
Patent CA-2927949-A1 (CA)
Title: Production of recombinant lubricin
Inventor: SCHMIDT TANNIN
IPC: C07K14/47
Filed: 2014-10-22
Abstract: Disclosed are new recombinant isoforms of human-like lubricin or PRG4 glycoprotein having outstanding lubrication properties and a novel glycosylation pattern, and methods for their manufacture at high levels enabling commercial production.
Patent CA-2928410-A1 (CA)
Inventor: HOBLIT T DOUGLAS
IPC: G01K3/04
Filed: 2014-10-22
Abstract: A system and method for monitoring temperatures in retail environment. The method includes associating temperature monitoring electronic shelf labels with a product and monitoring the temperature at the temperature monitoring electronic shelf label. When the monitored temperature is outside a predetermined range for the associated product, a warning is generated and transmitted to system users. Temperatures are also stored for each monitored product and zone for subsequent review. The temperature monitoring electronic shelf label comprises a temperature sensor integrated with an electronic shelf label, is mounted in a retail environment with temperature-sensitive products, and is connected to a low voltage power supply and communicates with an area controller.
Patent CA-2931369-A1 (CA)
Inventor: VENOT MARC
IPC: A47G21/10
Filed: 2014-09-29
Abstract: A pair of tongs having two arms including a pivotal engagement therebetween with a pin. Each arm includes a jaw displaced from the pivotal engagement. A locking sleeve includes a channel therethrough with opposed tracks to receive the pin. Stops limit movement of the locking sleeve on the arms. A closure at the end of the channel includes a cup engageable with the locking sleeve. The stop at the distal end of the channel includes an opening therethrough conterminous with the channel. Each arm also includes an outer profile curved inwardly toward the pivotal engagement across which the locking sleeve slides. The pivotal engagement includes oblong holes in the arms with a resilient element biasing the arms apart.
Patent CA-2932906-A1 (CA)
Title: Multiple data source aggregation for efficient synchronous multi-device media consumption
Inventor: TRIVEDI MEHUL
IPC: G06F15/16
Filed: 2014-09-29
Abstract: Methods and systems for efficient synchronous playback among a group of devices using both locally and remotely stored data from one or more content providers are provided. A content identification and matching system can be used to identify local content on the group of devices and match the local content to content available from remotely available libraries. A control and content delivery system can be used to allow multiple devices to synchronously play content from local or remote sources as available.
Patent CA-2935541-A1 (CA)
Title: Vacuum adsorption apparatus
Inventor: KOO HONG SIK
IPC: F16B47/00
Filed: 2015-01-08
Abstract: A vacuum adsorption apparatus is disclosed. The vacuum adsorption apparatus according to an aspect of the present invention comprises: an adsorption member vacuum-adsorbed by a vacuum chamber formed therein onto a surface-to-be-adsorbed; and an adjustment member coupled to the adsorption member so as to form a vacuum chamber, wherein the adsorption member comprises a first hard part to which the adjustment member is coupled and of which the location may be raised by the adjustment member, a deformation part of which one end is coupled to an end of the first hard part and of which the shape can be changed, and a second hard part coupled to the other end of the deformation part to support the deformation part and located in the outside of the first hard part.
Patent CA-2937015-A1 (CA)
Title: Traitement d'une neoplasie
Inventor: CADE DAVID
IPC: A61K31/505
Filed: 2015-01-23
Abstract: L'invention concerne une méthode de traitement du cancer chez un patient qui consiste à administrer au patient un régime de produit chimiothérapeutique en combinaison avec une particule radioactivement dopée, caractérisée en ce que les deux thérapies lorsqu'elles sont administrées au patient ont un effet anticancéreux amélioré.
Patent CA-2937846-A1 (CA)
Inventor: MINNIKANTI VENKATACHALA
IPC: C08J5/24
Filed: 2015-01-22
Abstract: A composite system for the reinforcement of physical structures includes a plurality of unidirectional fibers arranged with respective longitudinal axes generally parallel to each other over a substantial portion of a length of each unidirectional fiber. The plurality of unidirectional fibers are non-mechanically connected. A resinous material adheres the plurality of unidirectional fibers to each other such that each one of the plurality of unidirectional fiber is adhered to at least one adjacent one of the plurality of unidirectional fibers along a substantial portion of the length of the adjacent one of the plurality unidirectional fibers.
Patent CA-2938213-A1 (CA)
Title: Procedes ameliores pour traiter des substats d'adn
Inventor: MAKAROV VLADIMIR
IPC: C12N15/11
Filed: 2015-01-30
Abstract: L'invention concerne un procédé de ligature d'adaptateur aux extrémités des molécules d'ADN fragmentées double brin . L'invention rend superflu l'ajout d'un groupe phosphate aux extrémités 5' de fragments d'ADN. A défaut, les bases à extrémité 5' terminale endommagées en tant que résultat de la fragmentation physique de l'ADN, sont éliminées. Grâce à l'élimination d'une base endommagée, une base compatible avec une ligature avec un 5' phosphate est exposée, et l'efficacité d'une ligature d'adaptateur est rétablie, ce qui produit une augmentation significative du rendement d'une bibliothèque et de la capacité de construire des bibliothèques à partir de volumes d'ADN d'entrée réduits .
Patent CA-2938598-A1 (CA)
Inventor: BINGEMAN RON
IPC: C10M119/18
Filed: 2015-02-09
Abstract: The invention provides lubricating composition comprising: (1) a reaction product selected from the group consisting of: (a) a polyalkanoic or polyalkenoic acid derived from hydroxyfatty acids and a block copolymer selected from the group consisting of polyoxyethylene-polyoxypropylene and a reverse block copolymer of polyoxypropylene-polyoxyethylene-polyoxypropylene; (b) the reaction product of (a) with a maleic acid or anhydride; and (c) the reaction product of (a) with maleated soybean oil; and (2) at least one base oil selected from the group consisting of alkyl benzene, normal paraffin, isoparaffin, mineral oil and a-olefin.
Patent CA-2938754-A1 (CA)
Inventor: CHOW ARTHUR CARROLL
IPC: G06F7/00
Filed: 2016-08-12
Abstract: An apparatus for use in electronic document control includes a storage device a processor coupled to the storage device. The storage device storing software instructions for controlling the processor that when executed by the processor configure the processor to: receive a signal representing data including an original document, append a unique identifier to the original document to generate a modified document, generate a hash value of the modified document, and transmit the hash value corresponding to the modified document to an electronic distributed ledger.
Patent CA-2939186-A1 (CA)
Inventor: MASJEDIZADEH MOHAMMAD REZA
IPC: A61P17/00
Filed: 2015-02-20
Abstract: L'invention concerne des procédés de préparation de 2-[(3R)-3-[4-amino-3-(2-fluoro-4-phénoxy-phényl)pyrazolo[3,4-d]pyrimidin-1-yl]pipéridine-1-carbonyl]-4-méthyl-4-[4-(oxétan-3-yl)pipérazin-1-yl]pent-2-ènenitrile sous forme base libre (composé (I)), de sels du composé (I), et d'une forme à l'état solide desdits sels. L'invention concerne aussi des compositions pharmaceutiques comprenant ces sels et leur forme à l'état solide, et des procédés de traitement de maladies cancéreuses, auto-immunes et inflammatoires, au moyen du composé (I) ou d'un sel pharmaceutiquement acceptable de ce dernier.
Patent CA-2943562-A1 (CA)
Inventor: MCDONALD IAN JAMES
IPC: G06Q30/00
Filed: 2016-09-29
Abstract: Systems and methods for real-time drafting for transactions using a digital asset. A first party initiates a transaction including a transfer of a digital asset, such as a distributed ledger-based or blockchain-based currency. A central authority receives a transaction request and compares a value of the digital assets to be transferred by a first party to a total asset value in one or more accounts associated with the first party. lf the central authority determines that the total asset value is equal to or greater than the value of the digital assets to be transferred, the central authority provides authorization to complete the transfer without waiting for a confirmation from a distributed ledger. This mechanism provides a sufficient degree of certainty to allow use of digital assets as a medium of exchange in situations involving near real-time delivery of goods or services upon tender of payment.
Patent CA-2945344-A1 (CA)
Title: Systems and methods for tissue removal
Inventor: WACHLI SERENE
IPC: A61B17/32
Filed: 2015-04-23
Abstract: Systems and methods for preventing the seeding of cancerous cells during morcellation of a tissue specimen inside a patient's body and removal of the tissue specimen from inside the patient through a minimally-invasive body opening to outside the patient are provided. One system includes a cut-resistant tissue guard removably insertable into a containment bag. The tissue specimen is isolated and contained within the containment bag and the guard is configured to protect the containment bag and surrounding tissue from incidental contact with sharp instrumentation used during morcellation and extraction of the tissue specimen. The guard is adjustable for easy insertion and removal and configured to securely anchor to the body opening. Protection-focused and containment-based systems for tissue removal are provided that enable minimally invasive procedures to be performed safely and efficiently.
Patent CA-2945478-A1 (CA)
Inventor: HJELT JOONAS
IPC: H04W88/02
Filed: 2014-11-24
Abstract: A method, an apparatus and a computer program for setting up wireless data transfer, comprising monitoring network traffic from an apparatus; determining a context and/or origin of the network traffic; determining and presenting control options for setting up a wireless data transfer; selecting a control option based on user input; and routing the network traffic.