baber/WOPTO huggingface dataset:
Patent CA-2595861-A1 (CA)
Title: Purification of protected non-ionic oligonucleotides
Inventor: LINK FRITZ
IPC: C07H21/00
Filed: 2006-01-30
Abstract: A method for purifying a protected oligonucleotide comprising the steps of: a) - providing a solution of the protected oligonucleotide in at least one solvent A having a boiling point below the boiling point of a solvent B, -heating the solution at a temperature of at least 30~C and below the boiling point of the at least solvent A, - adding solvent B until precipitation of a material is visible in the solution, said solvent B being an alcohol having 1 to 6 C-atoms or a diol having 2 to 6 C-atoms, - allowing the solution to cool down under stirring until formation of a supernatant and a residue, - removing the supernatant or b) - providing solvent B, said solvent B being an alcohol having 1 to 6 C- atoms or a diol having 2 to 6 C-atoms, - heating solvent B at a temperature above 30~C and below the boiling point of solvent B, - adding a solution of a protected oligonucleotide in at least one solvent A until precipitation of a material is visible in the solution, - allowing the solution to cool down under stirring until formation of a supernatant and a residue, - removing the supernatant.
Patent CA-2597264-A1 (CA)
Inventor: SIMON AVRAM B
IPC: A61B5/02
Filed: 2006-01-18
Abstract: A method of calculating blood flow in an organ of a subject using output radiofrequency signals transmitted to the organ and input radiofrequency signals received from the organ, the method comprises determining a phase shift of the input radiofrequency signals relative to the output radiofrequency signals and using the phase shift to calculate the blood flow in the organ.
Patent CA-2597382-A1 (CA)
Inventor: HART PETER
IPC: E01F5/00
Filed: 2006-02-09
Abstract: A water detention system comprises a sub-base of crushed rock or stone (21) overlying an impermeable layer (29) which may be naturally-occurring, as in an impermeable sub-grade, or may be formed by an impermeable membrane (26) laid over the sub-grade prior to the sub-base layer. Over the sub-base layer is an incompletely impermeable layer (22) the impermeability of which is compromised by openings in the form of slits (12) or by spacing between adjacent strips forming the layer. These openings allow water to percolate downwardly through the layer (22) into the sub-base, but substantially inhibit the escape of moisture by evaporation thereby serving to retain the collected water. Above the incompletely impermeable layer (22) may be a laying course (20) of finer particulate material such as pea gravel over which may be laid a wear surface (18) of slabs or blocks (19) to form an area for traffic, such as a roadway or parking area.
Patent CA-2603011-A1 (CA)
Inventor: MILLER ROBERT
IPC: C09B69/08
Filed: 2006-03-31
Abstract: Processes for dyeing fabric are provided. The process can include continuously moving the fabric in a machine direction; removing folds or creases from the fabric; spraying a first surface of the fabric with a dye; and exposing the fabric to atmospheric steam after spraying the dye on the first surface but prior to the dye drying on the first surface so that the dye migrates from the first surface to a second surface of the fabric and reacts with and affixes to a component of the fabric.
Patent CA-2604971-A1 (CA)
Title: Dispositif de controle de la course d'une pointerolle d'un systeme d'alimentation d'une cellule d'electrolyse de production d'aluminium
Inventor: COUVREUR SEBASTIEN
IPC: C25C3/14
Filed: 2005-09-09
Abstract: Dispositif pour l'équipement d'une cellule comprenant un bain (4) d' électrolyse recouvert d'une croûte (5) , avec une pointerolle (13) déplaçable verticalement entre une position haute dans laquelle elle est au-dessus de la croûte et une position basse destinée à perforer la croûte et à venir en contact avec le bain, le dispositif (11) comportant des moyens de détection du contact électrique entre la pointerolle et le bain, ces moyens comprenant un circuit électrique (19) apte à effectuer une mesure électrique entre la pointerolle et un point (20) de la cellule pris comme référence électrique, et à agir immédiatement sur l'actionneur pour provoquer un déplacement vertical de la pointerolle vers le haut, lorsqu'une valeur prédéterminée d'une mesure électrique est atteinte. Le circuit électrique est relié à la pointerolle, à  la tige (14) de la pointerolle ou à la tige (17) de l'actionneur par des moyens de liaison aptes à créer un contact (24) ponctuel en au moins un point entre le circuit et la pointerolle, la tige de la pointerolle ou la tige de l'actionneur, ces moyens de liaison (23) étant soumis à des moyens élastiques les poussant en direction de la pointerolle, de sa tige ou de la tige de l' actionneur .
Patent CA-2605420-A1 (CA)
Inventor: WOODWARD RONALD O
IPC: H01L33/58
Filed: 2006-04-21
Abstract: Headlamp systems are provided that form desired beam patterns from light supplied by semiconductor light sources. The systems (20) include a source array of semiconductor light sources (32) and a lens system (4S) to produce a first component, such as spread light, of desired beam patterns and a source array of semiconductor light sources (36) and a lens system (52) to produce a second component, such as the hot spot components, of the desired beam patterns. Light from the semiconductor light sources of each source array (32,36) is transferred to the respective lens system (48,52) by a transfer device comprising a series of light pipes (40,44) which capture light emitte d by the semiconductor light sources (32,36) and emit the captured light adjacent the respective lens systems (48,52). One or both source arrays (32,36) can include additional semiconductor light sources which are selectively illuminated or extinguished to provide steering hot spots in the beam pattern to illuminate areas adjacent the vehicle over which the vehicle will be turned.
Patent CA-2607276-A1 (CA)
Title: Sclerostin fragments and anti-sclerostin antibodies
Inventor: ROBINSON MARTYN KIM
IPC: C07K14/51
Filed: 2006-04-28
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
Patent CA-2608245-A1 (CA)
Title: Process for the preparation of losartan potassium
Inventor: ARNALOT AGUILAR CARMEN
IPC: A61P9/12
Filed: 2006-05-05
Abstract: The invention relates to the preparation of losartan and losartan potassium.  More particularly, the invention relates to the preparation of losartan and losartan potassium in a simplified process that provides higher purity losartan potassium and losartan potassium having larger crystal sizes. The invention further includes formulating into readily usable dosage units for the therapeutic treatment (including prophylactic treatment) of mammals, including humans.
Patent CA-2608388-A1 (CA)
Title: A process for the dynamic resolution of (substituted) (r) - or (s) -mandelic acid
Inventor: BOSSON BO LARS GUSTAF
IPC: C07C51/487
Filed: 2006-05-22
Abstract: The present invention relates to a process for the resolution of mandelic acid derivative enantiomers from (racemic) mixtures by salt formation (see, for example, formula IIa) with chiral base cyclic amides, and racemisation of the unresolved enantiomer in the same process, wherein an additional racemising base may optionally be used, employing an acid : total base (i.e. cyclic amide and optional additional base) molar ratio of at least 1 : 1; provided that the cyclic amide base is present in a molar ratio of at least 0.75; and to the use of the resolved mandelic acid derivatives as intermediates suitable for large-scale manufacturing of, for example, pharmaceutical compounds; wherein R is selected from CHF2, H, C1-6 Alkyl, CH2F, CHCl2 and CClF2; and wherein n is 0, 1 or 2; R1 is H or C1-6 Alkyl and X is H, halo or C1-6 Alkyl.
Patent CA-2608784-A1 (CA)
Inventor: CAMERON RYAN
IPC: B01D53/44
Filed: 2007-10-24
Abstract: A gas separation system that extracts carbon dioxide from atmospheric air.  Carbon dioxide (CO2) is monitored with sensors and collected by intake rings of zeolite molecular sieves within pneumatic controlled chambers, and transformed by compression into liquid.   A vortex thrust for extricating the greenhouse gas is provided by a wind fan, or, turbofan depending on the structural size of the respiring tower. The system is powered by energy from solar, wind and self-generated fuel sources.   The tower anatomy is similar to an airplane fuselage utilizing a monocoque fabrication method. At optimum conditions the structure processes 9,407 metric tons of CO2 daily, thus producing a minimum of 6,688,565 liquid liters per annum of CO2 from cohesive air, based on 0.0445%  concentrations (ppm).   One million towers at 50 meters will remove 3.4 trillion tonnes annually of CO2, situated on quadrants at every 40 square kilometers of land.
Patent CA-2609131-A1 (CA)
Inventor: SHORE LAWRENCE
IPC: H01M4/88
Filed: 2006-03-28
Abstract: The membrane electrode assembly (MEA) of a PEM fuel cell is recycled by contacting the MEA with a lower alkyl alcohol solvent which separates the membrane from the anode and cathode layers of the assembly.
Patent CA-2614800-A1 (CA)
Title: Bacteriophage specifically for lysing propionibacterium acnes and uses thereof
Inventor: BOJAR RICHARD
IPC: A61K35/76
Filed: 2006-07-07
Abstract: There is provided a bacteriophage capable of lysing a P. acnes bacterium and incapable of lysing a bacterium which is not P. acnes , and which is incapable of sustaining lysogeny in a bacterium. There is also provided a pharmaceutical composition comprising such a bacteriophage.
Patent CA-2616050-A1 (CA)
Inventor: PEDROTTI WOLFGANG
IPC: B62D25/08
Filed: 2006-07-12
Abstract: The invention relates to a front-end vehicle structure (2) for a commercial vehicle, comprising a forward crash zone (6) and a rear crash zone (8) relative to the longitudinal direction (4) of the vehicle. The forward crash zone (6) and the rear crash zone (8) are interconnected via an intermediate structure (10) which is mounted therebetween and extends substantially perpendicular to the longitudinal direction (4) of the vehicle such that a force that is applied to the forward crash zone (6) can be transmitted to the rear crash zone (8) via the intermediate structure (10).
Patent CA-2620566-A1 (CA)
Title: Glucopyranosyl-substituted benzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
Inventor: EICKELMANN PETER
IPC: C07D309/10
Filed: 2006-08-28
Abstract: Glucopyranosyl-substituted benzyl-benzene derivatives of the general formula (I) where the groups R1 to R6 as well as R7a, R7b, R7c are defined according to claim 1, including the tautomers, the stereoisomers thereof, the mixtures thereof and the salts thereof. The Compounds according to the invention are suitable for the treatment of metabolic disorders.
Patent CA-2622316-A1 (CA)
Title: Email server with proxy caching of message identifiers and related methods
Inventor: CLARKE DAVID J
IPC: H04L12/58
Filed: 2005-09-27
Abstract: An electronic (email server) includes a proxy that obtains mappings for UID's, a cache in which the mappings of new UID's and message ID's are cached, and a proxy operative for receiving at least one of a Get, Delete or Move request for a MsgID that has not been cached and mapping the MsgID.and "n" number of other MsgID's around the MsgID that had not been cached.
Patent CA-2624800-A1 (CA)
Inventor: EARL T KISER
IPC: B65D5/72
Filed: 2006-10-24
Abstract: A three part container system. The first part is an outer rigid container formed with a mouth defining an opening into the outer container, the outer container also being perforated therethrough. The second part is an inner container positioned within the outer container, the inner container formed with a mouth defining an opening into the inner container, the mouth of the inner container being positioned in and sealed to or adjacent to the mouth of the outer container, at least a portion of the inner container being collapsible so that the inner container can be filled with a liquid. The third part is a turret fitted directly or indirectly by way of the outer container to the mouth of the inner container. The turret contains a one way valve in liquid communication with the mouth of the inner container by way of a passageway in the turret, the turret defining a mouth in liquid communication with the one way valve by way of a passageway in the turret so that if the inner container contains a liquid and the collapsible portion of the inner container is held above the turret, air can flow through the perforation in the outer container into the space between the outer container and the inner container and the liquid in the inner container will flow through the one way valve and out of the mouth of the turret as the inner container collapses within the outer container, and so that if the turret is held above the inner container, flow of air back into the inner container is substantially prevented by the closure of the one way valve.
Patent CA-2629050-A1 (CA)
Title: Procede de fabrication de nanotubes de carbone a partir de matieres premieres renouvelables
Inventor: BORDERE SERGE
IPC: C10J1/213
Filed: 2008-04-04
Abstract: La présente invention a pour objet un procédé de fabrication de nanotubes de carbone, comprenant les étapes suivantes : a) la synthèse d'alcool(s) par fermentation d'au moins une matière végétale et éventuellement la purification du produit obtenu ; b) la déshydratation du ou des alcool(s) obtenu(s) en a) pour produire, dans un premier réacteur, un mélange d'alcène(s) et d'eau et éventuellement la purification du produit obtenu ; c) l'introduction, notamment la mise en lit fluidisé, dans un second réacteur, d'un catalyseur pulvérulent à une température allant de 450 à 850.degree.C, ce catalyseur comprenant au moins un métal catalytique supporté par un substrat solide inerte, les grains de catalyseur ayant un d50 inférieur à 300 .mu.m ; d) la mise en contact de l'alcène produit en b) avec le catalyseur pulvérulent, éventuellement en lit fluidisé, de l'étape c) pour former en surface dudit catalyseur des nanotubes de carbone et de l'hydrogène par décomposition catalytique dudit alcène ; e) la récupération des nanotubes de carbone produits en d). L'invention porte aussi sur les nanotubes susceptibles d'être obtenus suivant le procédé précité, qui peuvent être avantageusement utilisés dans tous les domaines d'application des nanotubes de carbone connus.
Patent CA-2629582-A1 (CA)
Inventor: CHAVES VALLEJO MARIA C
IPC: H01R33/76
Filed: 2008-04-23
Abstract: A meter center includes three feeder bus bars, three supply bus bars, each supply bus bar being electrically connected to a corresponding feeder bus bar, and a number of meter socket assemblies. Each meter socket assembly includes two bus jumpers, each bus jumper including a first end and a second end, the second end of a first bus jumper being selectively electrically connected to a first supply bus bar, the second end of a different second bus jumper being selectively electrically connected to a different second supply bus bar, two load bus bars, insulative support members coupled to a number of the supply bus bars, the insulative support members including a first end coupled to the bus jumpers and an opposite second end supporting the load bus bars, and a meter socket including terminals electrically connected to the first ends of the bus jumpers and to the load bus bars.
Patent CA-2630155-A1 (CA)
Inventor: STEGMAIER TRUMAN J
IPC: F16L3/12
Filed: 2008-05-01
Abstract: A pipe hanger system includes a pair of brackets and a pipe connection member selectively slidable along the brackets. The brackets each include a center section sized to be received between two building members on standard spacing and a pair of mounting tabs positioned on opposite ends of the center section. The center section includes a mounting portion having and a pair of ninety degree twists, each of the twists located between the mounting portion and a respective one of the mounting tabs such that the mounting portion lies in a plane substantially perpendicular to a plane defined by the mounting tabs. The center section also preferably includes a pair of lateral offsetting legs positioned between the mounting tabs and the respective ninety degree twists.
Patent CA-2631473-A1 (CA)
Title: Agricultural furrowing tool
Inventor: BERGEN HENRY J
IPC: A01C5/06
Filed: 2008-04-04
Abstract: A ground engaging furrowing tool for paired row seeding comprising a body having a forward leading point, a bottom and laterally outwardly extending wing members. Each wing member including a leading edge that flares rearward to a trailing edge to form a generally V-shaped profile bottom surface, the trailing edge of each wing member including a seed outlet only open in a rearward direction.
Patent CA-2632299-A1 (CA)
Title: System and method for control and adaptation of carrier infrastructure and process using formal carrier product definition
Inventor: PINTSOV LEON A
IPC: G06Q30/00
Filed: 2008-05-26
Abstract: An automated process that allows the posts to obtain a computer description of mailer's requirements for new carrier products and a description of available carrier operational constraints and capabilities in computer processable format;  translating the mailer's requirements for the new carrier products into a sequence of computer actionable instructions that may be exercisable by carrier operations; and comparing by the computer the sequence of computer actionable instructions and the carrier operational constraints and capabilities to determine feasibility of the mailers requirements.
Patent CA-2633684-A1 (CA)
Title: Rna interference mediated inhibition of hepatitis c virus (hcv) gene expression using short interfering nucleic acid (sina)
Inventor: JADHAV VASANT
IPC: A61K9/127
Filed: 2006-12-18
Abstract: The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity. The present invention is also directed to compounds, compositions, and methods relating to traits, diseases and conditions that respond to the modulation of ex-pression and/or activity of genes involved in gene expression pathways or other cellular processes that mediate the maintenance or development of such traits, diseases and conditions. Specifically, the invention relates to double stranded nucleic acid molecules in-cluding small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules capable of mediating RNA interference (RNAi) against gene expression, including cocktails of such small nucleic acid molecules and lipid nanoparticle (LNP) formulations of such small nucleic acid molecules. The present invention also relates to small nucleic acid molecules, such as siNA, siRNA, and others that can inhibit the function of endogenous RNA molecules, such as endogenous micro-RNA (miRNA) (e.g, miRNA inhibitors) or endogenous short interfering RNA (siRNA), (e.g., siRNA inhibitors) or that can inhibit the function of RISC (e.g., RISC inhibitors), to modulate gene expression by interfering with the regulatory function of such endogenous RNAs or proteins associated with such endogenous RNAs (e.g., RISC), including cocktails of such small nucleic acid molecules and lipid nanoparticle (LNP) formulations of such small nucleic acid molecules. Such small nucleic acid molecules and are useful, for example, in providing compositions to prevent, inhibit, or reduce diseases, traits and conditions that are associated with gene expression or activity in a subject or organism.
Patent CA-2634238-A1 (CA)
Inventor: JOHNSON PAUL E
IPC: G01N15/14
Filed: 2007-01-08
Abstract: An invention is described which allows measurement of the concentration of fluorescent particles (210) in a flowing (laminar) fluid by imaging the flow (214) with a video camera or the like. A beam of illumination is used to illuminate the target particles. Imaging optics (408, 412) are arranged to view the focal plane to form an image of the multiple fluorescent sample particles in the flow stream; a camera records the image formed by the imaging optics, and a counting algorithm (812) enumerates the particles. Operational parameters of the system are adjusted (824) according to an initial estimate of particle density (828), for example flow rate (824a), exposure time, and sampling interval (824b). In addition, the counting algorithm is selected according to the estimated particle density.
Patent CA-2634405-A1 (CA)
Title: Cargo container hinge structure
Inventor: KEATING JOHN R
IPC: B60R25/00
Filed: 2008-06-06
Abstract: A cargo container hinge structure having first and second hinge members. Each hinge member includes a mounting portion and a hinge portion. The mounting portion of the first hinge member is configured to facilitate attachment of the hinge member to a cargo container door. The mounting portion of the second hinge member is configured to facilitate attachment of the second hinge member to a rigid door frame on the cargo container. The hinge portions of the first and second hinge members operably combine with each other to accommodate a hinge pin used to secure the hinge members in a predetermined relation relative to each while allowing for pivotal movement of the cargo container door between a closed position and an open position and relative to the frame. A security apparatus, arranged in operable combination with the hinge members, detects and provides a visual indication whether the cargo container door connected to the hinge structure has been moved from the closed position.
Patent CA-2638668-A1 (CA)
Inventor: SUESS JEREMY
IPC: A61K31/4166
Filed: 2007-02-28
Abstract: Therapeutic and prophylactic treatments of aquatic species and aquatic diseases through the controlled introduction of a heterocyclic N-halamine into an aquatic habitat.
Patent CA-2641962-A1 (CA)
Inventor: CERTAIN BERNARD
IPC: B64C27/12
Filed: 2008-10-20
Abstract: L'invention concerne un giravion (10) comportant un rotor principal (11), un turbomoteur (13), et un mécanisme (BTP) de transmission couplé au rotor et au turbomoteur pour permettre l'entrainement du rotor par le turbomoteur. Le turbomoteur comporte une turbine libre (132) reliée au mécanisme de transmission (BTP) par un arbre (15, 15a, 15b, 16, 18). Le giravion comporte un compresseur externe (19) agencé pour être entrainé par la turbine libre (132) ou par un moteur électrique, ainsi qu'un conduit (21) de transport d'air reliant le compresseur externe (19) au turbomoteur pour délivrer en entrée (22) du turbomoteur de l'air comprimé par le compresseur externe.
Patent CA-2642218-A1 (CA)
Title: Track setter
Inventor: AUDET CARL
IPC: E01H5/00
Filed: 2008-10-29
Abstract: A track setter is described herein comprising a generally rectangular frame, a mounting assembly for pivotably mounting the frame to a tractor, a conventional track setter, a compactor/waver, a snow regenerator, a pivotable leveler, and two parallel keels.
Patent CA-2644092-A1 (CA)
Inventor: BLENCOE JAMES G
IPC: C22B1/02
Filed: 2007-02-28
Abstract: In a method of extracting lithium from a lithium bearing mineral, the mineral is reacted with a basic material of sufficient strength to dissolve the mineral, in order to produce a product mixture containing lithium. The lithium is then recovered from the product mixture. A method of extracting lithium from a lithium bearing mineral may consist of a two-step process. An industrial scale method of extracting lithium from a lithium bearing mineral can be conducted at a temperature not greater than about 500 °C and without the production of sulfur. A lithium metal can be produced by the method.