baber/WOPTO huggingface dataset:
Patent IL-93938-A0 (IL)
Title: Novel quinoline derivatives,preparation processes thereof,and antibacterial agents containing the same
IPC: C07D521/00
Filed: 1990-03-28
Abstract: Antibacterial quinolone derivatives represented by the following formula [I] and salts thereof are disclosed. <CHEM> wherein R<1> means a hydrogen atom or a carboxyl-protecting group; R<2> denotes a hydrogen or halogen atom or a hydroxyl, lower alkoxyl, amino, aralkylamino, or mono- or di-(lower alkyl)amino group; A represents an oxygen or sulfur atom or N-R<3> in which R<3> is a hydrogen atom or an amino-protecting group; X is a hydrogen or halogen atom; Y means a nitrogen atom or C-R<4> in which R<4> is a hydrogen or halogen atom or a lower alkyl or lower alkoxyl group; and Z denotes a halogen atom or a substituted or unsubstituted heterocyclic group having at least one nitrogen atom as a hetero atom.
Patent IL-96742-A0 (IL)
Title: Method for filling receptacles with products in accordance with a predetermined pattern
IPC: B65B5/10
Filed: 1990-12-20
Abstract: A method for filling receptacles with products in accordance with a predetermined pattern comprises the steps of: conveying the products in two or more separate files (4,6), transferring the products one by one to two supports (7,8), picking the individual products up by a suction effect (13) for transferring them to associated receptacles, positioning cros-barriers (22) in said receptacles in aid of the formation of rows of the products in each receptacle by transverse displacement of the latter, retaining the last completed row of the products as the receptacles are advanced, and repeating this cycle with transverse displacement in the opposite direction in successive cycles until completion of the layer or layers of the products. <IMAGE>
Patent FI-20031120-A0 (FI)
Inventor: ASHAMMAKHI NUREDDIN
IPC: A61L31/14
Filed: 2003-07-31
Abstract: Bone fixation or augmentation in a mammalian body to enhance the mechanical strength of a fracture is provided by reinforcement fixing bone ends together using the implant device. A resorbable device can be rendered anti-osteolytic by incorporating materials such as bisphosphonates. It can also be rendered osteoconductive by the incorporation of an osteoconductive material such as bioactive glass or TCP. The implant device has a matrix as one phase, where the matrix is made of a bioresorbable polymer. One phase of the implant is made from self-reinforcing elements and the matrix contains an antiosteolytic agent component. The implant contains further osteoconductive and/or osteoconductive material.
Patent FI-20070539-A0 (FI)
Inventor: TYNI TAPIO
IPC: G01G/
Filed: 2007-07-09
Abstract: The present invention discloses a solution for improving the accuracy of a load weighing signal in an elevator system. In the invention the load weighing signal expressing the sum of the forces exerted on the elevator car or on the drive machinery or on the elevator car and the car sling is received from the load weighing arrangement; the measuring signal about the vertical acceleration of the elevator car when the elevator car is moving or stationary is received from the measuring means of acceleration fixed in connection with the elevator car or with the car sling; and the load weighing signal is compensated with the acceleration signal measured by the measuring means of acceleration.
Patent IL-104179-A0 (IL)
Title: Novel solid pharmaceutical dispersions
IPC: A61J3/02
Filed: 1992-12-18
Abstract: A novel solid pharmaceutical dispersion that improves the bioavailability of poorly water soluble drugs is produced by combining the drug with a polymer carrier such as polyvinylpyrrolidone. The drug is combined with the carrier without the need for using organic solvents or melting temperatures (fusion) through the use of a transition compound such as polyethylene glycol which partially solubilizes the drug and/or plasticizes the polymer.
Patent IL-115195-A0 (IL)
Title: Amino acid-substituted benzoylguanidines a process for their preparation their use as a medicament or diagnostic agent and a medicament containing them
IPC: A61P3/10
Filed: 1995-09-06
Abstract: Benzoyl guanine derivs. of formula(I) and their salts are new. One of the substits. R1-R3 = Y-Ph-Ä(CH2)k-CHR7-CO-R8Ü; and the others = 1-8C alkyl, 2-8C alkenyl, (CH2)mR14, SO2NHC(=Y')NR18R19, H, halo, CN, Z(CH2)p-CqF2q+1, SOuR22, CONR23R24, COR25, SO2NR26R27, OR35 or NR35R36; Ph = phenylene (opt. mono- or di-substd. by Fl, Cl, CF3, Me, OH, OMe or NR37R38); R37, R38 = H or Me; Y = a bond, O, S or NR9; R9 = H or 1-4C alkyl; R7 = OR10 or NR10R11; R10 = H 1-8C alkyl, 1-8C alkanoyl, 1-8C alkoxycarbonyl, benzyl, or benzyloxycarbonyl; R11 = as R10 or trityl; R8 = OR12 or NR12R13; R12, R13 = H, 1-8C alkyl or benzyl; R14 = 3-8C cycloalkyl or phenyl (both opt. substd. by 1-3 F, Cl, CF3, Me, OMe, or NR15R16); R15, R16 = H or Me; Y' = O, S or NR20; R18, R19 = H, 1-8C alkyl, 3-6C alkenyl or (CH2)tR21; or R18+R19 = A; R21 = 5-7C cycloalkyl or phenyl, (both opt. mono- to tri-substd. by F, Cl, OMe or 1-4C alkyl); R20 = as R18 or amidine; Z = a bond, O, S or NR28; R22 = 1-8C alkyl, 3-6C alkenyl, (CH2)nR29 or CF3; R23, R25, R26 = as R22 or H; R24, R27 = H or 1-4C alkyl; or R23+R24, R26+R27 = A; A = (CH2)4 or (CH2)5 (both opt. having a CH2 replaced by O, S, NH, NMe or N-benzyl; R28 = H or 1-3C alkyl; R29 = 3-7C cycloalkyl or phenyl (both opt. substd. by 1-3 F, Cl, CF3, Me, OMe or NR30R31; R30, R31 = H or 1-4C alkyl; R35, R36 = H or 1-6C alkyl; or R35+R36 = (CH2)y (opt. having a CH2 gp. replaced by O, S, NH, NMe or N-benzyl); R4, R5 = H, 1-4C alkyl, F, Cl, OR32, NR33R34 or CrF2r+1; R32-R34 = H or 1-3C alkyl; k, n, t = 0-4; m, u, p = 0-2; q = 1-6; r = 1-4; and y = 4-7.
Patent IL-126257-A0 (IL)
Title: Immuno-magnetic cell separation used in identification of genes associated with site-preferenced cancer metastasis formation
IPC: C12N5/10
Filed: 1997-03-25
Abstract: Method for identifying genes with site specific or site preferred expression in target cells that are initially detected and isolated by repeated immuno-magnetic procedures. The purified target cells are then exposed to known cloning procedures. Preferred target cells are malignant cells, e.g. metastatic cells. Gene cloning methods may include the differential display or substractive hybridization approaches.
Patent IL-127644-A0 (IL)
Title: A process for producing a titanium-ceramic adhesive composite system
IPC: C23C14/48
Filed: 1997-06-19
Abstract: PCT No. PCT/DE97/01343 Sec. 371 Date Jan. 27, 1999 Sec. 102(e) Date Jan. 27, 1999 PCT Filed Jun. 19, 1997 PCT Pub. No. WO97/48835 PCT Pub. Date Dec. 24, 1997The invention relates to a process for producing a titanium and ceramic adhesive composite system, and a titanium and ceramic adhesive system produced therefrom. The system can be used to improve the adhesive of ceramics, intended for pure titanium or titanium alloys, to a structure consisting of pure titanium or a titanium alloy. The improvement is attained in that silicon ions (4) are inserted into the surface (1) of a structure consisting of pure titanium or a titanium alloy by ion implantation with ion beams (3) between the atoms (5) of the titanium or the atoms (5) of the titanium alloy. The silicon ions form a titanium and silicon layer (2) in the surface (1) of the structure in the penetration layer of the ion implantation, on which titanium and silicon layer crystalline, non -metallic inorganic materials are applied, and an adhesive composite is produced with said materials.
Patent IL-131008-A0 (IL)
Title: Lipid complexed and liposomes of highly insoluble platinum complexes
IPC: A61K47/48
Filed: 1998-01-28
Abstract: A pharmaceutical composition comprising a lipid complex or a liposome of a phospholipid and a water-insoluble platinum dicarboxylate and method for the preparation of such compositions are described.
Patent IL-134381-A0 (IL)
Title: Non-invasive method for disease diagnosis
IPC: A61B5/053
Filed: 2000-02-03
Abstract: Diagnostic method, which comprises selecting 24 biologically active points (BAPs), measuring the skin resistance at said points, plotting the average resistance for said points as an isoelectric line and defining a normal corridor. The method is characterized at (A) a stimulation is applied to each of the said points, (B) the skin resistance is measured once again at said points after applying the stimulation, (C) the results of the two sets of measurements are compared, and (D) diagnostic conclusions are reached from their comparison.
Patent IL-135185-A0 (IL)
Title: Thermal arched beam microelectromechanical devices and associated fabrication methods
IPC: H04Q1/16
Filed: 1998-08-28
Abstract: A MEMS actuator is provided that produces significant forces and displacements while consuming a reasonable amount of power. The MEMS actuator includes a microelectronic substrate, spaced apart supports on the substrate and a metallic arched beam extending between the spaced apart supports. The MEMS actuator also includes a heater for heating the arched beam to cause further arching of the beam. In order to effectively transfer heat from the heater to the metallic arched beam, the metallic arched beam extends over and is spaced, albeit slightly, from the heater. As such, the MEMS actuator effectively converts the heat generated by the heater into mechanical motion of the metallic arched beam. A family of other MEMS devices, such as relays, switching arrays and valves, are also provided that include one or more MEMS actuators in order to take advantage of its efficient operating characteristics. In addition, a method of fabricating a MEMS actuator is further provided.
Patent IL-147766-A0 (IL)
Title: Therapeutic compounds comprised of anti-fc receptor binding agents
IPC: A61P33/00
Filed: 2000-07-25
Abstract: Multispecific molecules which induce effector cell-mediated killing of target cells are disclosed. The molecules are "multispecific" because they bind to multiple (two or more), distinct targets, one of which is an Fc receptor on the surface of an immune cell. Multispecific molecules of the invention include molecules comprised of at least one portion which binds to an Fc receptor, such as an Fc gamma  receptor (e.g., Fc gamma RI) or an Fc alpha  receptor, and at least one other portion which binds to a different target, such as an antigen on a tumor cell or a pathogen. Multispecific molecules of the invention also include antigen "multimer complexes" comprised of multiple (i.e., two or more) portions which bind to a molecule on an antigen presenting cell (APC), such as an Fc receptor, linked to one or more antigens. These multimer complexes target antigens, such as self-antigens, to APCs to induce and/or enhance internalization (endocytosis), processing and/or presentation of the antigen by the APC. Therefore, these molecules can be used to induce or enhance an immune response either <i>in vivo</i> or <i>in vitro</i> against a normally non-immunogenic protein, such as a self-antigen. In a particular embodiment, at least one portion of the multispecific molecules comprises a humanized or human antibody or antibody fragment (e.g., ScFv or Fab') which binds to an Fc receptor or a receptor on a target cell (e.g., EGF-R or HER2).
Patent IL-151522-A0 (IL)
Title: System, device and method for rapid packet filtering and processing
IPC: H04L12/66
Filed: 2001-02-26
Abstract: A system, a device and a method for accelerating packet filtration by supplementing a firewall with a pre-filtering module. The pre-filtering module performs a limited set of actions with regard to the packets, according to whether the packets are received from a connection which has been previously permitted by the firewall. If the packets are received from such a permitted connection, then the pre-filtering module forwards the packets to their destination, optionally performing one or more actions on the packets. Otherwise, the packets are forwarded to the firewall for handling. Preferably, once the firewall has transferred responsibility for the connection to the pre-filtering module, or "off-loaded" the connection, the firewall does not receive further packets from this connection until a timeout occurs for the connection, or a packet is received with particular session-control field values, such that the connection is closed. Optionally and preferably, the pre-filtering module is implemented as hardware.
Patent IL-153495-A0 (IL)
Title: Production method of substituted benzenes
IPC: C07C69/63
Filed: 2002-12-17
Abstract: An ester compound of formula (1) <CHEM>  can be produced by making a compound given by formula (2): <CHEM> react with an alkali metal salt of acetic acid in the presence of an aromatic hydrocarbon, and the obtained ester compound of formula (1) react with an alkali metal hydroxide and water to give a 3-phenoxypropanol compound of formula (3): <CHEM>
Patent IL-156921-A0 (IL)
Title: Distal targeting of locking screws in intramedullary nails
IPC: A61B17/58
Filed: 2003-07-14
Abstract: In a distal targeting system a hand-held location pad is integral with a guide section for a drill or similar surgical instrument, and has a plurality of magnetic field generators. A sensor, such as a wireless sensor, having a plurality of field transponders, is disposed in an orthopedic appliance, such as an intramedullary nail. The sensor is capable of detecting and discriminating the strength and direction of the different fields generated by the field generators. Control circuitry, preferably located in the location pad is responsive to a signal of the sensor, and determines the displacement and relative directions of an axis of the guide section, and a bore in the orthopedic appliance. A screen display and optional speaker in the location pad provide an operator-perceptible indication that enables the operator to adjust the position of the guide section so as to align its position and direction with the bore. <IMAGE>
Patent IL-157087-A0 (IL)
Title: A method for identifying a function of a gene sequence
IPC: C12N15/10
Filed: 2002-01-25
Abstract: The present invention relates to methods and compositions for the efficient identification of one or more functionalities of a product encoded by a nucleic acid sequence of interest. The methods utilize the abilities to over and/or under express the product in a cell, as well as the combination of these results, to permit the identification of at least one of the product's cellular or in vivo functionality.
Patent IL-180294-A0 (IL)
Title: Device for enabling angular position of a projectile fin
Filed: 2006-12-25
Abstract: The measuring device for the angular position of a fin or rudder on a projectile that pivots relative to a fixed support (3) comprises a rotor (13) attached to the fin or rudder axle (4), and a wound stator (16) fixed to the support. The stator, which is set in a recess and fixed to the support by an overmoulded material (18) such as a polymerised resin, has at least two windings - induction and induced - and the rotor co-operates with the stator to form a rotary transformer.
Patent IL-181298-A0 (IL)
Title: Solid and crystalline ibandronate sodium and processes for preparation thereof
Filed: 2007-02-13
Abstract: The present invention relates to a crystalline form of ibandronate sodium characterised by x-ray reflections at about 6.2, 15.7, 26.3, 32.6 and 35.6 ± 0.2° 2¸ with further x-ray reflections at about 17.6, 19.4, 26.9, 31.7 and 38.7 ± 0.2° 2¸. The x-ray powder diffraction diagram is shown in the figure. Pharmaceutical compositions comprising said crystalline ibandronate sodium are also claimed.
Patent IL-185031-A0 (IL)
Title: Method for the preparation of pregabalin and salts thereof
Filed: 2007-08-02
Abstract: Processes for preparing and purifying Pregabalin and salts thereof are provided.
Patent RO-128726-A0 (RO)
Title: Chamber sliding mechanism
Inventor: DUMBRAVA MIHAI
IPC: B62D63/06
Filed: 2013-03-08
Abstract: The invention relates to a chamber sliding mechanism, built on the basis of a floating deformable parallelogram mechanism and a leveling caster, which function by two, coupled in a desmodromic manner, and are used for multiplying the useful area in quick mountable-dismountable containers, houses or caravans for any destination. According to the invention, the mechanism may be built as a cascade chambers sliding mechanism () or may be built as a symmetrical chamber sliding mechanism (), two cascade chamber sliding mechanisms () or two symmetrical sliding mechanisms (), the mechanisms being positioned in mirror symmetry, in vertical-parallel planes, coupled in a desmodromic manner by means of a driving mechanism assembly () and forming the cascade chamber sliding assembly () and the symmetrical chamber sliding assembly (), respectively, the sealing at the level of each sliding being made with a sealing assembly with truncated cone bellows ().
Patent RO-133735-A0 (RO)
Title: Planning process based on an algorithm of optimal division of work load
Inventor: IONICĂ ANDREEA CRISTINA
IPC: G06Q10/06
Filed: 2019-03-18
Abstract: The invention relates to a process for planning work load, based on an algorithm determining the order of performing work tasks for various project types, taking into account the mutual influence that work tasks have upon one another and the priorities set in accordance with the clients' requests. According to the invention, the process comprises: taking over (4) the clients' needs, determining (5) the clients' requests, determining (6) the work tasks corresponding to clients' requests, establishing (7) the interdependence between the work tasks and prioritizing the work tasks, using an algorithm (3, 8), based on an indicator quantifying the clients' requests meeting degree.
Patent AP-2000001791-A0 (AP)
Title: Cellulosic fiber composites.
Inventor: MEDOFF MARSHALL
IPC: C08L101/00
Filed: 2000-04-14
Abstract: Composites of a resin and texturized cellulosic or lignocellulosic fiber, and methods for forming the composites, are disclosed
Patent IE-910535-A1 (IE)
Title: Diterpenes having immunomodulatory action
Inventor: RADUNZ HANS-ECKART
IPC: A61K31/045
Filed: 1991-02-15
Abstract: The use of diterpenes of formula (I) as pharmaceutical agents is new. In (I), R1 = CH2-C(CH3) = CHR3 or CH2-CH(CH3)-CH2-R3. R3 = CH2OH, CHO, COOH or COOR4. R4 = 1-5C alkyl. A = CH-CH3 or C = CH2. R2 = H, pentose or hexose sugar, di-or oligosaccharide or an amino sugar. (I) are new as long as R1 is not -CH2-C(CH3) = CHCH2OH or -CH2-C(CH3) = CHCHO when A is C = CH2 and R2 is galactose. The use of a glycosylated derivative of (I) is specifically claimed.
Patent IE-910914-A1 (IE)
Title: Liquid composition for the relief of premenstrual and¹menstrual discomforts
Inventor: CALAM HENRY D
IPC: A61K45/00
Filed: 1991-03-19
Abstract: A liquid composition for the relief of premenstrual and menstrual discomfort comprising, as active pharmaceutical agents, an effective amount of an analgesic, an antihistamine, and a diuretic, said active agents being dissolved in a liquid vehicle, said composition containing 5-25 percent by volume alcohol and being flavored with active flavoring elements selected from the group consisting of citrus, vanilla, and mint, said active flavoring ingredients being present in an amount sufficient to mask the unpleasant taste of the pharmaceutically active agents.
Patent MA-27484-A1 (MA)
Title: Cigarette chauffee electriquement comprenant un arome a liberation controlee
Inventor: WOODSON BEVERLEY C
IPC: A24D3/17
Filed: 2005-04-29
Abstract: L'invention concerne des cigarettes chauffées électriquement qui sont utilisées dans un système électrique servant à fumer et qui comportent un additif libérateur d'arôme ainsi qu'un agent de sorption permettant d'éliminer efficacement un ou plusieurs constituents en phase gazeuse de la fumée de tabac du courant principal. L'additif libérateur d'arôme comprend au moins un arôme. Cet arôme est libéré dans la cigarette lorsque l'additif libérateur d'arôme atteint au moins une température minimale pendant que la cigarette est fumée. L'additif libérateur d'arôme peut se présenter sous plusieurs formes telles que des perles, des pellicules ou des composés d'inclusion. Cette invention se rapporte en outre aux systèmes électriques servant à fumer qui contiennent lesdites cigarettes chauffées électriquement, à des procédés de production de ces cigarettes, ainsi qu'à des procédés pour fumer lesdites cigarettes.
Patent MA-38741-A1 (MA)
Title: Amorces et sondes pour l'amplification, la détection et/ou la quantification du génome du virus de l'hépatite c
Inventor: AIT BENHASSOU HASSAN
IPC: C12Q1/68
Filed: 2015-12-29
Abstract: La présente invention concerne le domaine des maladies virales. Elle concerne en particulier l'amplification, la détection et/ou de la quantification, d'un ou de différents génotypes du virus de l'hépatite virale type c(vhc) présents dans un même ou différents échantillons biologiques, au moyen d'un ou de plusieurs nouveaux sets d'amorces et de sondes. Cette invention peut aussi s'appliquer lorsque les séquences d'acides nucléiques du vhc présentent une variabilité, et ce pour autant de séquences qu'elles possèdent et permettant l'hybridation avec les sets d'amorces et de sondes utilisées.
Patent MA-42863-A1 (MA)
Title: Composition de fibre de verre à haut module d'élasticité, et fibre de verre et matériau composite de celle-ci
Inventor: CAO GUORONG
IPC: C03C13/00
Filed: 2016-03-07
Abstract: L'invention concerne une composition de fibre de verre à haut module d'élasticité, et une fibre de verre et un matériau composite de celle-ci. La teneur, exprimée en pourcentage en poids, de chaque composant de la composition de fibre de verre est la suivante : 53 à 68 % de sio
Patent MA-43457-A1 (MA)
Title: Nouveaux peptides, combinaisons de peptides et supports pour utilisation dans le traitementimmunothérapeutique de divers cancers
Inventor: WEINSCHENK TONI
IPC: C07K14/47
Filed: 2016-08-26
Abstract: La présente invention concerne des peptides, des protéines, des acides nucléiques et des cellules pour utilisation dans des procédés immunothérapeutiques. La présente invention concerne, en particulier, l'immunothérapie du cancer. La présente invention concerne, en outre, des épitopes peptidiques des lymphocytes t associés à une tumeur, seuls ou en combinaison avec d'autres peptides associés à une tumeur, qui peuvent, par exemple, servir de principes pharmaceutiques actifs pour des compositions vaccinales qui stimulent les réponses immunitaires antitumorales, ou pour stimuler des lymphocytes t ex vivo et les transférer aux patients. Des peptides liés aux molécules du complexe majeur d'histocompatibilité (cmh), ou des peptides en tant que tels, peuvent également être des cibles d'anticorps, de récepteurs des lymphocytes t solubles et d'autres molécules de liaison.
Patent MA-49540-A1 (MA)
Title: Dispositif pour respiration artificielle
Inventor: LAGHZIOUI YASSINE
IPC: A61M16/00
Filed: 2020-04-20
Abstract: L’invention concerne un dispositif de ventilation contrôlée en volume à piston améliorée par le développement d’un labyrinthe à la place de la tuyauterie et l’amélioration des systèmes de capteurs. Ce dispositif permet trois modes de respiration : ventilation contrôlée (vc), ventilation assistée contrôlée (vac) et ventilation spontanée (vs) avec la possibilité de régler le nombre de cycles et du volume nécessaire à l’inspiration du patient. Le dispositif comporte deux cylindres avec un labyrinthe en quatre parties chacun pour garantir un maximum de sécurité, un fonctionnement continu du système et une facilité de montage et de démontage. Cette solution permet par ailleurs d’optimiser les coûts de production au vu de l’accessibilité de fabrication de l’ensemble des composants.