baber/WOPTO huggingface dataset:
Patent EA-003708-B1 (EA)
Title: Method for separating and/or isolating plasma proteins by annular chromatography
Inventor: BUCHACHER ANDREA
IPC: C07K14/755
Filed: 1999-05-27
Abstract: 1. A process for the separation and/or isolation of human plasma proteins, from a blood plasma or a mixture containing virus-inactivated plasma proteins using the method of annular chromatography, characterized in that, the separation is made in separation medium wherein having a layer of application medium which is spherical particles with hydrophobic surface. 2. The process according to claim 1, characterized in that said mixture contains at least two plasma proteins to be separated. 3. The process according to claim 1, wherein said separation medium having the annular design is used for ion-exchange, gel permeation, molecular size exclusion or affinity chromatography or chromatography based on hydrophobic interactions. 4. The process according to claims 1, wherein said plasma proteins are inter-alpha-trypsin inhibitor, alpha1-antitrypsin, anti-thrombin III, immune globulins, such as IgG, human serum albumin or glycoproteins, preferably from the clotting cascade, or vitamin K dependent blood clotting factors. 5. The process according to at least one of claims 1, characterized in that said plasma proteins are selected from blood clotting factors VIII, IX, and thrombin. 6. The process according to any of claims 1, characterized in that the functions of mixing, of separating the plasma proteins and of the fractioning are performed continuously. 7. The process according to any of claims 1, characterized in that the separation medium is continuously regenerated and equilibrated, simultaneously with the separation of the plasma proteins. 8. The process according to any of claims 1, characterized in that when a material for adsorption chromatography is used as the separation medium, at least two different eluents are simultaneously passed through said separation medium having the annular design. 9. The process according to any of claims 1, characterized in that at least two different separation media are employed in layers. 10. The process according to any of claims 1, characterized in that a polymeric block material is employed as said separation medium.
Patent EA-004343-B1 (EA)
Title: A method and device for regulating the flow rate of formation fluids produced by an oil well
Inventor: CORRE PIERRE-YVES
IPC: E21B43/14
Filed: 2001-04-27
Abstract: 1. A method of regulating the flow rate of formation fluids produced from a determined zone of an underground well whose cased wall is provided with orifices through which said formation fluids can pass, said method consisting in applying a tubular structure along the casing in said zone, which tubular structure prevents the fluids from flowing directly while also preserving a flow path along which the fluids can flow via the annular space outside the tubular structure so as to generate head loss. 2. A method according to claim 1, in which said path is helical. 3. A device for regulating the flow rate of formation fluids produced from a determined zone of an underground well whose wall is cased with casing provided with perforation orifices to allow said formation fluids to pass through it, said device being constituted by a radially-expandable tubular structure that can be applied against the inside wall of the casing, the structure being provided with means for preserving the flow of the fluids via a path running along the casing and along the structure, in order to generate head loss. 4. A device according to claim 3, characterized in that said flow means are constituted by removal grooves extending from the central portion of the outside face of the tubular structure to at least one of the ends of the tubular structure. 5. A device according to claim 4, characterized in that said removal grooves are disposed helically. 6. A device according to claim 4, characterized in that said removal grooves are disposed in the form of zigzag lines. 7. A device according to any one of claims 3 to 6, in which, in its central portion serving to cover the perforation zone, the tubular sleeve is provided with draining grooves for collecting the incoming flow. 8. A device according to any one of claims 3 to 7, in which the tubular sleeve is constituted by a braid of flexible strands embedded in a settable composite material, and, on its outside face, it has an elastomer skin in which the removal and drainage grooves are provided. 9. A method for putting the device according to claim 8 in place in a well equipped with casing and with production tubing, said method comprising: - inserting a laying tool via the casing, which tool comprises an inflatable die provided with heater elements and covered with the tubular sleeve, which die is suspended from a cable containing electricity feed means and pumping means; - inflating the die until the sleeve is applied against the inside wall of the casing; - heating the die to polymerize the settable composite material; - deflating the die while leaving the sleeve in place; and removing the laying tool from the well.
Patent EA-012080-B1 (EA)
Title: Caspase inhibitors containing isoxazoline ring
Inventor: CHANG HYE-KYUNG
IPC: C07D413/04
Filed: 2004-08-26
Abstract: The present invention relates to an isoxazoline derivative as an inhibitor against various caspases, a process for preparing the same, and a therapeutic composition for preventing inflammation and apoptosis comprising the same.
Patent EA-008954-B1 (EA)
Title: Gas-discharge reflector lamp
Inventor: TSAY VICTOR IVANOVICH
IPC: H01J61/02
Filed: 2006-05-26
Abstract: The proposed invention relates to the electro technical industry, in particular, to improve a design of gas discharge reflecting lamps for use in general and special-purpose illumination. The invention is aimed at reduction the cost price of gas discharge reflecting lamps, and increasing its quality due to the use traditionally round-symmetrical bulbs and obtaining uniform thickness of a glass, keeping high luminous flux of a lamp. The technical result is achieved by using the gas discharge reflecting lamp containing the arc-tube, mounted on wires in a bulb, not less than half of which internal surface is covered with reflecting layer so that the plane extending through its longitudinal edges, is parallel to a longitudinal axis of arc-tube, being at a distancefrom the bulb symmetry axis constituting 0.04-0.11 the maximal internal diameter of bulbwherein cross-section edges of a reflecting layer are located in places of transition of throat and dome of a bulb into elliptical part; the arc-tube is placed so, that in the cross-section section extending through the center of the bulb ellipsoid, the relation of distance from an axis of arc-tube up to the nearest surface of a reflecting layerto distance from an axis of arc-tube up to edge of the reflecting layerlocated on longitudinal section, lays within the limits of 0.56-0.68, and at least, one wire is placed between the arc-tube and the reflecting layer in a longitudinal plane of symmetry. The achieved result provides to reduce the cost price of a lamp, to keep high luminous efficiency, allowing to realize profit at a rate of 1 million 200 thousand rubles at the price of lamps 210 rubles / 1 piece and annual manufacture - 200 thousand pcs.
Patent EA-014000-B1 (EA)
Title: Polyolefin foam, process for making thereof and use
Inventor: STADLBAUER MANFRED
IPC: C08J3/20
Filed: 2006-08-16
Abstract: A polyolefin foam comprises 30 to 94 wt% of a foamable polyolefin and 6 to 70 wt% preferably at least 20 wt% of a particulate solid material, and wherein the foamable polyolefin has a weight average branching index g<[Lambda]> < 0.9, capable of absorbing high amounts of liquid comprising more than 5% (g/g). Besides, the present invention relates to a process for making said foam and use thereof
Patent EA-024851-B1 (EA)
Title: Food with cheese contained therein
Inventor: SCHMID MANUEL WILLIBALD
IPC: A23C19/09
Filed: 2009-05-22
Abstract: The present invention relates to a food with cheese contained therein, said food typically derived from food based on ground meat by replacing the ground meat with cheese particles, a method for the manufacture thereof, use thereof in the manufacture of convenience foods and convenience foods so obtained. The present invention further relates to intermediate products for the manufacture of the food according to the invention, a method for manufacturing a cheese material suitable as a starting material for the manufacture of the food according to the invention, and the cheese material so obtained.
Patent EA-019461-B1 (EA)
Title: Prefabricated building of light metal structures
Inventor: GLUKHOVTSEV VSEVOLOD EDUARDOVICH
IPC: E04B1/19
Filed: 2011-03-09
Abstract: The invention relates to construction, in particular, to prefabricated frame different-purpose buildings. The inventive result provides increasing bearing capacity of the building. The prefabricated building of light metal structures comprises transverse frames of the carcass from pillars, which are hingedly connected to the foundation, and crossbars made of welded double tees of alternating cross section, combined during assembly by means of flange joints, stands of framed structures and multilayer barrier wall and roof structures of the roof. The surface of the barrier structures that are inverted inside the building is formed by walls of cassettes fixed to the elements of the carcass and the stands of the framed structure and made of the metal sheet with Γ-shaped ribs bent at longer sides to form a cavity filled by heat insulation. The external surfaces of wall and roof structures are fixed to the ribs of the cassettes via an additional layer of heat insulation. The building is equipped with channel-like stiffening elements installed inside cassettes and connected with their walls to the walls of Γ-shaped stiffening ribs. In the roof structure the stiffening elements rest against the frame crossbars, and in the wall structure they are installed in cassettes adjacent to the framing of window and door openings and in the cassettes that form the pedimental part of the wall.
Patent EA-021365-B1 (EA)
Title: Wearable iontophoresis device and method of fabricating the same
Inventor: EISCHEN KATHLEEN A
IPC: A61N1/30
Filed: 2009-08-31
Abstract: A wearable iontophoresis device for the prolonged delivery of a positively charged pharmaceutical species from a salt formulation is disclosed that includes a readily oxidizable metal-based sacrificial anode in the form of a generally planar layer having a connecting area that has a width that is sufficient to insure complete consumption of the oxidizable metal wherein the anode is configured to have a minimum operating life of at least 6 hours under skin-safe conditions, and a drug delivery gel pad in electrical contact with said anode for accommodating a gel containing a positively charged pharmaceutical species in salt form formulated for transdermal delivery.
Patent EA-018244-B1 (EA)
Title: Key device with movable key combination element and lock assembly
Inventor: BEN-AHARON EFFI
IPC: E05B35/00
Filed: 2009-08-25
Abstract: A key device for use with more than one lock, the key device including a shaft portion, and at least one movable key combination element retained within the shaft portion and including first and second portions adjacent one another, the first portion of the at least one movable key combination element being located along on the shaft portion and the second portion of the at least one movable key combination element being located offset to the first portion.
Patent EA-022668-B1 (EA)
Title: Sulphur cement pre-composition and sulphur cement product
Inventor: DE BOER PAUL
IPC: C09D7/63
Filed: 2010-01-28
Abstract: A sulphur cement pre-composition, comprising sulphur, a first organosilane and a second organosilane, and a sulphur cement product comprising sulphur, a particulate inorganic material, a first organosilane and a second organosilane are disclosed. The first organosilane comprises one or more functional groups chosen from thiol, sulphide, amine or alkenyl groups. The second organosilane does not comprise any thiol, sulphide, amine or alkenyl groups. Processes for making the sulphur cement pre-composition and the sulphur cement product are also disclosed.
Patent EA-025443-B1 (EA)
Title: USE OF GRANATICIN B AS Cdc7 KINASE INHIBITOR
Inventor: FRATTINI MARK
IPC: A61K31/122
Filed: 2011-03-08
Abstract: The invention relates to the use of a compound of formulagranaticin B (II) or a pharmaceutically acceptable salt thereof, pharmaceutical composition thereof and kit for the treatment or prevention of different cancers in a human.
Patent EA-030460-B1 (EA)
Title: Plants with increased fruit size
Inventor: VRIEZEN HENDRIK WILLEM
IPC: C12N15/82
Filed: 2011-05-27
Abstract: The invention relates to the field of transgenic and non-transgenic plants with novel phenotypes. The present invention provides Solatium lycopersicum Auxin Response Factor 9 (SlARF9) proteins and nucleic acid sequences encoding these, which are useful in conferring novel phenotypes to plants, especially increased fruit size.
Patent EA-024445-B1 (EA)
Title: Method for processing rape seeds
Inventor: DEREVENKO VALENTIN VITALIEVICH
IPC: C11B1/06
Filed: 2013-03-29
Abstract: The invention relates to production of vegetable oils from oil seeds and can be used in oil-extracting branch to obtain oil from rape seeds and high-protein oilcake or meal. In the disclosed method rape seeds are crushed by single impact, with obtained core fraction before squeezing oil from it in press-extruder being conditioned at temperature 70-80°C, which makes it possible to reduce energy consumption for their processing with minimal oiling of fruit shell.
Patent EA-029503-B1 (EA)
Title: Method of producing recombinant adamts13 in cell culture
Inventor: GRILLBERGER LEOPOLD
IPC: C12N9/48
Filed: 2011-07-08
Abstract: Among other aspects, the present invention relates to cell culture conditions for producing high molecular weight vWF, in particular, highly multimeric WF with a high specific activity and ADAMTS13 with a high specific activity. The cell culture conditions of the present invention can include, for example, a cell culture medium with an increased copper concentration and/or cell culture supernatant with a low ammonium (NH) concentration. The present invention also provides methods for cultivating cells in the cell culture conditions to express high molecular weight vWF and rA13 having high specific activities.
Patent EA-030398-B1 (EA)
Title: Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
Inventor: SOLL MARK D
IPC: A61P33/00
Filed: 2013-01-31
Abstract: The invention relates to oral veterinary compositions for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting active compound of formula (I)wherein the variables B, B, B, R, R, R, R, n are defined in the claims; in combination with a pharmaceutically acceptable carrier. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in animals comprising administering the compositions of the invention to the animal in need thereof.
Patent EA-028021-B1 (EA)
Title: Led lamp
Inventor: KOGDANIN ARTEM IGOREVICH
IPC: F21V14/00
Filed: 2013-06-07
Abstract: The invention relates to illumination devices. The technical result consists in changing the light intensity curve without disassembling the lamp itself or the parts thereof. The LED lamp comprises a housing containing a printed circuit board with LEDs, a primary optical system and a secondary optical system. The LEDs form segments onto which the primary optical system is installed directly, the secondary optical system being positioned thereabove and containing a group of lenses and installed with the possibility of radial displacement relative to the axis of the lamp.
Patent EA-031093-B1 (EA)
Title: Recombinant carboxydotrophic acetogenic microorganism, method for the production thereof and method for the production of products using same
Inventor: KOEPKE MICHAEL
IPC: C12P7/40
Filed: 2013-01-31
Abstract: The invention relates to a recombinant carboxydotrophic acetogenic microorganism producing a reduced amount or no 2,3-butanediol upon fermentation of a substrate comprising carbon monoxide, the microorganism comprising at least one genetic modification which disrupts the expression or activity of enzyme capable of converting pyruvate to acetolactate, enzyme capable of converting acetolactate to acetoin and/or enzyme capable of converting acetoin to 2,3-butanediol, thus the 2,3-butanediol biosynthesis pathway is disrupted, the microorganism is produced from the parental microorganism selected from Clostridium autoethanogenum, Clostridium ljungdahlii, Clostridium ragsdalei and Clostridium coskatii. The invention also relates to a method for the production of such microorganism and a method for the production of products using the same.
Patent EA-029647-B1 (EA)
Title: Method of manufacturing a launder and launder
Inventor: VAARNO JUSSI
IPC: C22B3/22
Filed: 2013-06-12
Abstract: A method of manufacturing a launder (1) to be used in co-operation with a solvent extraction settler (2) comprises manufacturing at the site of manufacture, such as in an engineering workshop, a plurality of self-supporting launder element modules (3), each having exterior dimensions, strength and handling and securing means (4) conforming to shipping container standards, transporting the launder element modules (3) to the site of installation as normal freight by transport equipment, such as trucks, trailers and container ships, capable of handling and transporting shipping container standard compatible units, and assembling at the site of installation the launder element modules (3) into a module group (5) forming a complete launder. The launder (1) comprises a launder module group (5) consisting of self-supporting launder element modules (3), each having exterior dimensions, strength and handling and securing means (4) conforming to shipping container standards to enable shipping container standard compatible transportability.
Patent EA-028753-B1 (EA)
Title: Method and apparatus in the manufacture of a spirally wound and welded tube
Inventor: GLASBERG CHRISTIAN
IPC: F16L9/16
Filed: 2013-11-19
Abstract: The present invention relates to a method and apparatus in the manufacture of a spirally wound and welded tube. A thermoplastic profile (1) is slided along a path on sliding means (12, 13) arranged in an axial direction of said tube and defining a cylindrically shaped winding surface with a diameter corresponding to the inner diameter of the tube to be manufactured. The profile (1) is directed along a spiral path (S) towards a previous turn of said profile by means of radial rollers (10) spaced along said spiral path by adjusting the position (d) of the rollers. Opposite edges (1a, 1b) of said profile turns are welded together by providing an extruded welding mass (6) between said profile turns. The welded tube (4) is fed from the welding station by means the rollers (10) by sliding it onto a rotating support (2A).
Patent EA-029148-B1 (EA)
Title: Tall oil fatty acid for use in treatment and animal feed supplements and compositions
Inventor: VUORENMAA JUHANI
IPC: A23K10/32
Filed: 2014-05-09
Abstract: The present invention relates to a tall oil fatty acid for use in the prevention of growth of harmful bacteria in the animal digestive tract and/or in the prevention of intestinal disorders. The invention further relates to a feed supplement and a feed composition comprising a tall oil fatty acid.
Patent EA-030694-B1 (EA)
Title: Manipulation tool and method of using same, and an adapter for use together with the manipulation tool
Inventor: BYE ARNULF
IPC: E21B31/00
Filed: 2014-09-24
Abstract: A manipulation tool (1) for connection to and operation of a controllable well device (120) comprising an elongated housing (3) with a first end portion (5) and a second end portion (7); a gripping device (10) arranged in the first end portion (5) of the housing (3) and being configured to provide a releasable engagement with the well device (120) that is to be controlled by means of the manipulation tool (1), the gripping device (10) comprising means (12, 14) for resisting rotational and axial movement between the housing (3) and the well device; the manipulation tool (1) further comprising at least one manipulation device (20, 30) which is axially displaceable between a first position and a second position along a longitudinal axis of the housing (3) and rotatable around the longitudinal axis of the housing (3); a first driving device (40) so as to produce axial displacement of the at least one manipulation device (20, 30); a second driving device (70) so as to produce rotation of the at least one manipulation device (20, 30); the first driving device and the second driving device being connected to a control unit (80) which is arranged to control the energy supply to the driving devices.
Patent EA-036665-B1 (EA)
Title: Method for development of an isolated lithologically or tectonically screened heterogeneous oil-saturated reservoir
Inventor: DEMYANENKO NIKOLAY ALEXANDROVICH
IPC: E21B49/08
Filed: 2016-11-28
Abstract: This invention relates to the field of developing isolated lithologically or tectonically screened multi-zone oil-saturated reservoirs (lenses), with heterogenous geological and physical properties, which are tapped using a single well. It ensures the maximum oil recovery rate and cumulative oil production while reducing the development period. A method for development of an isolated lithologically or tectonically screened heterogeneous oil-saturated reservoir, tapped using a single vertical well located in the reservoir central or edge zone, comprises determination of the zone of wedging-out or tectonic screening of the reservoir, reservoir profile analysis, drilling of at least one side hole through the vertical well, with penetration to the oil-saturated reservoir at a distance of at least 50 m from the vertical hole to the area with the highest recoverable reserves, and completion of the top oil-filled reservoir sublayer, perforation of the vertical well in the oil-filled reservoir interval, installation of at least one packer above the perforation zone, injection of working fluid to the reservoir and formation fluid withdrawal. According to the invention, the side hole is made with a near-vertical end, which is used for penetration into oil-saturated sublayers, with the inclination angle of 5-20°, at least one system for reservoir coverage by production, oriented by a direction angle, including an expulsion system and a formation fluid collection system, is formed in each sublayer using the vertical well hole and near-vertical end of the side hole by their perforation and creation of deep-penetrating radial filtration channels at minimum one level.
Patent EA-032972-B1 (EA)
Title: Heterocyclic carboxylic acids as activators of soluble guanylate cyclase
Inventor: BRENNEMAN JEHROD BURNETT
IPC: C07D417/14
Filed: 2015-07-21
Abstract: The present invention relates to compounds of formula Iand pharmaceutically acceptable salts thereof, wherein R, R, R, R, R, R, R, R, B, V, W, X, Y, Z and m are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.