baber/WOPTO huggingface dataset:
Patent WO-2020167703-A1 (WO)
Title: Systèmes et méthodes de dosage continu
Inventor: MCCULLOUGH ADAM
IPC: A61M5/152
Filed: 2020-02-11
Abstract: L'invention concerne un système d'administration de médicament comprenant un récipient d'administration comprenant un corps de récipient conçu pour recevoir un médicament à l'intérieur de celui-ci, une conduite d'alimentation et un dispositif de surveillance du débit. Le récipient d'administration comprend en outre des orifices d'entrée et de sortie et est fabriqué à partir d'un matériau élastique qui exerce une force de pression sur le médicament pour l'expulser hors de l'orifice de sortie. La conduite d'alimentation est couplée de manière fonctionnelle à l'orifice de sortie pour l'administration du médicament à un utilisateur. Le dispositif de surveillance du débit est couplé de manière fonctionnelle au récipient d'administration et/ou à la conduite d'alimentation, et comprend un dispositif de commande numérique, une soupape de fluide couplée de manière fonctionnelle au dispositif de commande numérique, et une seringue à mouvement de translation en communication fluidique avec la soupape de fluide et couplée de manière fonctionnelle au dispositif de commande numérique. La soupape de fluide, le piston à mouvement de translation et le dispositif de commande numérique coopèrent pour réguler le débit du médicament.
Patent WO-2020172328-A1 (WO)
Inventor: LIU DONGFANG
IPC: C07K14/54
Filed: 2020-02-19
Abstract: Disclosed herein are methods and compositions for generating immunotherapeutic cells ( e.g. , NK and T cells) with enhanced cytotoxicity and capacity for expansion thereof. The methods and compositions disclosed herein can further be used for enhanced expansion of CAR-modified NK and T cells with increased cytotoxicity.
Patent WO-2020219209-A1 (WO)
Title: Anomaly detection framework
Inventor: RAMASWAMY SANJAY H
IPC: G06F16/20
Filed: 2020-03-28
Abstract: A method may include accessing a plurality of data items, each data item in the plurality of data items having a plurality of stored dimensions; selecting a subset of the data items based on a shared value of a first dimension of plurality of dimensions; identifying an outcome metric for the first group; determining a control group for comparison with the first group with respect to the outcome metric, wherein data items in the control group are determined based on dimensions that influence the first dimension and the outcome metric; determining that the outcome metric of the first group is anomalous with respect to the outcome metric of the control group; and presenting a notification to a computing device indicating the anomaly.
Patent WO-2020205919-A1 (WO)
Inventor: OLZMANN JAMES ARTHUR
IPC: G01N33/50
Filed: 2020-04-01
Abstract: Disclosed herein are methods and compositions for determining ferroptosis sensitivity, inhibiting or reducing ferroptosis resistance, and treating diseases and disorders related to ferroptosis.
Patent WO-2020223675-A1 (WO)
Inventor: CHAPUT JOHN
IPC: G01N21/17
Filed: 2020-05-01
Abstract: Systems and method for sorting droplets includes a microfluidic chip or substrate having a droplet sorting channel coupled at an upstream location to a droplet inlet channel, the droplet sorting channel coupled at a downstream location to a waste channel and a collection channel. The device includes an optical interrogation device configured to illuminate the droplets passing through the sorting channel with excitation light from an excitation light source and capturing emitted fluorescent light and generating an output signal correlated to the fluorescence of the droplets. An actuator (electrode) is disposed in the microfluidic chip or substrate and coupled to a signal driver (e.g., a high voltage amplifier). The device or system uses a programmable controller configured to receive the output signals from the optical interrogation device and trigger the signal driver to actuate the actuator to direct the droplets into the collection channel.
Patent WO-2020236436-A1 (WO)
Inventor: SIVARAMAN MUKUND
IPC: G06F115/02
Filed: 2020-05-07
Abstract: An example method of implementing an application for a system-on-chip (SOC) having a data processing engine (DPE) array includes determining a graph representation of the application, the graph representation including nodes representing kernels of the application and edges representing communication between the kernels, mapping, based on the graph, the kernels onto DPEs of the DPE array and data structures of the kernels onto memory in the DPE array, routing communication channels between DPEs and circuitry of the application configured in programmable logic of the SOC, and generating implementation data for programming the SOC to implement the application based on results of the mapping and the routing.
Patent WO-2021167635-A1 (WO)
Title: Sprayable cementitious composition
Inventor: LI VICTOR C
IPC: B28B1/32
Filed: 2020-05-14
Abstract: A sprayable ductile metal-like cementitious composition (SDMCC) comprising: a composite binder, fibres, and water; wherein the composite binder comprises a cement component and a pozzolan component. The SDMCC may exhibit expansion on curing and strain hardening behaviour. The SDMCC is useful for repairing and/or retrofitting building structures such as pipelines. Also described are methods for the preparing the SDMCC.
Patent WO-2021188130-A1 (WO)
Title: Method and system for generating an application programming interface based on declarative schemas for individual services
Inventor: THAKUR AVEER RATAN
IPC: G06F8/61
Filed: 2020-05-15
Abstract: Certain aspects of the present disclosure provide techniques for generating an application programming interface (API) for a plurality of associated services. The method generally includes retrieving a declarative schema for a service of a plurality of services in an application programming interface (API). A language object for the sendee is generated from a data object definition in the declarative schema associated with the service. Generally, the language object is configured to handle data events generated by the service. A service controller for the service is generated from a sen-ice definition in the declarative schema associated with the respective service. Generally, the service controller is fronted by a gateway for external sources to invoke one or more functions implemented by the sendee. An application programming interface (API) is exposed for the service independently of details of APIs for the associated services to one or more external services.
Patent WO-2020263853-A1 (WO)
Inventor: MEIJER JOHN
IPC: E21B4/00
Filed: 2020-06-23
Abstract: An improved swivel with increased sealing capability at fluid pressures up to 20 ksi and at fluid temperatures as high as 250°F and as low as 35°F. The swivel may be relatively compact, being less than 8 feet in overall length and can operate unpressurized with axial loads of at high as 1,400,000 lbs. The swivel may comprise a swivel mandrel rotationally coupled with a swivel housing. Rotational bearings units can be securely held using cartridge carriers. A pressure seal may be formed between the swivel mandrel and swivel housing via a redundant seal stack.
Patent WO-2020264249-A1 (WO)
Title: Multiphysics automated support generation for additively manufactured components
Inventor: Raghavan Sathyanarayanan
IPC: B33Y50/02
Filed: 2020-06-26
Abstract: A method, medium, and system to execute an additive manufacturing (AM) simulation on a model of a part; determine, based on the AM simulation, a prediction of a temperature and displacement distribution in the part at a particular time in the AM process; apply the predicted temperature and displacement distributions in the part as a boundary conditions on a support design space to determine a temperature distribution throughout the support design space; and execute a thermal-structural topology optimization based on the determined temperature and displacement distributions throughout the support design space   to determine a distribution of material in the design space for a thermal support structure to interface with the part that optimally reduces a thermal gradient in the part with a minimum of material and results in the generation of an optimized AM support structure.
Patent WO-2020264320-A1 (WO)
Inventor: ZHAO ZHANLUE
IPC: G06T7/20
Filed: 2020-06-26
Abstract: Methods, apparatus, and systems are provided for calibrating an optical flow (OF) sensor by using an inertial measurement unit (IMU) measurements in a planar robot system.
Patent WO-2021016563-A1 (WO)
Title: Systems and visualization interfaces for orbital paths and path parameters of space objects
Inventor: HENDRIX DOUGLAS
IPC: G06F3/048
Filed: 2020-07-24
Abstract: A display system can be configured to receive, via a user interface, a first identifier associated with a first space object and determine a first maneuver of the first space object. The first maneuver can include a perturbation of the path of the first space object. Based on the first identifier and the first maneuver, the display system can identify one or more path parameters associated with a path of the first space object and generate a display interface. The display interface can include a longitude-time graph having a longitude axis spanning from a lower-longitude limit to an upper-longitude limit and a time axis spanning from the lower-time limit to the upper-time limit and an indication of the one or more path parameters.
Patent WO-2021025892-A1 (WO)
Inventor: SHEALY JOHNNY
IPC: F16J15/34
Filed: 2020-07-28
Abstract: A shaft seal includes a shaft engaging portion configured to couple to a shaft extending through a wall. The shaft seal includes a flange configured to sealingly engage the wall. The shaft seal includes a body extending between the shaft engaging portion and the flange. The seal is configured to allow radial and axial movement of the shaft relative to the wall while maintaining a seal between the flange and the wall.
Patent WO-2021034583-A1 (WO)
Title: Socket for upper extremity prosthesis
Inventor: LACHAPPELLE EASTON
IPC: A61F2/78
Filed: 2020-08-13
Abstract: A socket (3100) may be for coupling a prosthetic upper extremity (200", 300") to a residual limb of a user. The socket may include a proximal socket portion (3110) and a distal socket portion (3150) coupled to the proximal socket portion by a polycentric joint (3180). The polycentric joint may include a plate (3181) having a first end (3182) coupled to the proximal socket portion via a first fastener, and a second end (3183) coupled to the distal socket portion via a second fastener. The proximal socket portion may be rotatable relative to the distal socket portion about a first axis passing through the first fastener and about a second axis passing through the second fastener.
Patent WO-2021045893-A1 (WO)
Title: Beam scanner with reflective polarizer
Inventor: WHEELWRIGHT BRIAN
IPC: G02B27/01
Filed: 2020-08-15
Abstract: A beam scanner of a projector-based near-eye display includes a prismatic element with a reflective polarizer and a quarter-wave waveplate. The beam-folding prismatic element receives a polarized light beam from a light source and couples the beam to a tiltable reflector, e.g. a 2D tiltable MEMS reflector, for angular scanning the beam. The light beam impinging onto the tiltable reflector is separated from the light beam reflected from the tiltable reflector by polarization. The polarization-based separation is achieved by causing the light beam to propagate through the QWP before and after impinging onto the tiltable reflector. Upon double propagation of the light beam through the QWP, the beam changes its polarization to an orthogonal polarization, which enables its separation from the impinging beam. The beam scanner may receive multiple light beams from multiple sources. A projector and a near-eye display based on such beam scanners are disclosed.
Patent WO-2021041736-A1 (WO)
Inventor: HAWKINS III
IPC: B62K3/02
Filed: 2020-08-27
Abstract: L'invention concerne un dispositif d'entraînement de vélo fixe, d'intérieur, qui offre des avantages par rapport aux conceptions classiques de vélos d'exercice. Le vélo fixe peut comprendre un mécanisme d'inclinaison/pivotement pour orienter le vélo d'intérieur pour simuler une descente ou une montée. Le vélo d'intérieur peut comprendre des éléments de cadre souples et élastiques pour supporter le dispositif d'entraînement d'intérieur de sorte qu'il se déplace d'un côté à l'autre dans certaines situations de conduite, simulant ainsi le mouvement d'oscillation d'un côté à l'autre d'un vélo d'extérieur dans les mêmes situations de conduite. Le vélo d'intérieur peut comprendre plusieurs combinaisons d'ajustements de cadre afin de fournir des dimensions configurables du vélo d'intérieur pour ajuster le cadre pour s'adapter correctement à l'utilisateur, qui peut être ajusté sur la base des dimensions correspondantes du vélo d'extérieur d'un utilisateur. Encore d'autres aspects du dispositif de vélo fixe peuvent aider à créer une sensation « d'extérieur » lors de l'utilisation du dispositif.
Patent WO-2021046483-A1 (WO)
Title: Multi-modal industrial securing devices
Inventor: DIMITROV MARTIN
IPC: F16B2/08
Filed: 2020-09-05
Abstract: The present disclosure provides a multi-modal fastener including a first end, a second end opposite the first end, a first face, and a second face opposite the first face, the multi-modal fastener comprising: a length of material extending substantially from the first end to the second end; a securing portion disposed proximal to the second end; and a mating portion disposed proximal to the first end and configured to reversibly mate with the securing portion, wherein the length of material is movable between a first stable resting configuration and a second stable resting configuration.
Patent WO-2021050780-A1 (WO)
Title: Drive system for a poultry and/or swine enclosure
Inventor: GREIVE RAYMOND
IPC: A01K31/18
Filed: 2020-09-10
Abstract: A drive system configured to move an elongated mobile poultry and/or swine enclosure. The drive system may comprise an axle at least 20 feet in length. The drive system may include multiple wheels coupled to the axle. The multiple wheels may have diameters between 6 and 36 inches. The drive system may include a motor coupled to the axle that causes the axle and/or the multiple wheels to rotate and move the elongated mobile poultry enclosure across a field. The elongated mobile poultry enclosure may be at least 40 feet in length and the drive system is coupled to the elongated mobile poultry enclosure.
Patent WO-2021076412-A1 (WO)
Title: Methods and systems of supplying therapeutic gas based on inhalation duration
Inventor: AYLSWORTH ALONZO C
IPC: A61M16/00
Filed: 2020-10-09
Abstract: Supplying therapeutic gas based on inhalation duration. At least some of the example embodiments are methods including: sensing a current inhalation of the patient; providing a flow of therapeutic gas to the patient based on the sensing; and ceasing the flow of therapeutic gas to the patient based on a value indicative of previous inhalation duration.
Patent WO-2021091697-A1 (WO)
Inventor: JEROMIN AARON CHANDLER
IPC: G03B21/62
Filed: 2020-10-22
Abstract: A system includes a projection device configured to project images onto a receiver surface of a viewing device. The viewing device includes a screen having the receiver surface and a viewing surface opposite the receiver surface. The screen is configured to permit transmission of the images through the screen, from the receiver surface, to the viewing surface such that the images are viewable on the viewing surface. The viewing device also includes a focusing lens configured to focus the images for a user when wearing the viewing device. Further, the system includes a tracking system configured to determine a location and orientation of the receiver surface of the viewing device. The projection device is configured to adjust image properties of the images based at least in part on the determined location and orientation of the receiver surface.
Patent WO-2021087371-A1 (WO)
Title: Polymeric fiber materials for thermal and mechanical protection and methods of making
Inventor: GONZALEZ GRANT
IPC: C08G69/32
Filed: 2020-10-30
Abstract: System, devices and methods for the fabrication of polymeric fibers, as well as resulting polymeric fibers, polymeric fiber materials and uses thereof are described. The polymeric fibers include poly (para- phenylene terephthalamide) (PPTA) fibers having an average fiber diameter in a range of 300 nm to 3 μm, and having an average Young's modulus in a range of 1 GPa to 100 GPa. Some materials including a plurality of the polymeric fibers have a thermal conductivity (k) in a range of 0.005 W/(m▪K) to 10 W/(m▪K) as measured perpendicular to a plane of the material.
Patent WO-2021108091-A1 (WO)
Inventor: STAUSS JOHN ROBERT
IPC: G01V3/00
Filed: 2020-11-03
Abstract: Aspects of the present invention include a system and method for differentiating one or more objects detected behind an opaque surface, comprising, a plurality of sensors, controlled by one or more processors, configured to collect in parallel, sensor data of the one or more objects behind an opaque surface, the one or more processors are configured to analyze the sensor data to identify estimated regions of the one or more objects behind the opaque surface, the one or more processors are further configured to differentiate the estimated regions of the one or more objects behind the opaque surface, and, the one or more processors are further configured to inform a user, via a user interface, of the one or more objects within the estimated regions behind the opaque surface.
Patent WO-2021108437-A1 (WO)
Inventor: FOELSCH BORIS
IPC: G16H40/63
Filed: 2020-11-24
Abstract: A device pairing system is configured to determine that an auxiliary device detects an ultrasonic beacon emitted by a beacon generator and identify, in response to the determination that the auxiliary device detects the ultrasonic beacon, a medical system associated with the ultrasonic beacon. The auxiliary device is further configured to communicatively pair, in response to the identification of the medical system, the auxiliary device with the identified medical system.
Patent WO-2021113215-A1 (WO)
Title: Implantable medical device including cable fastener
Inventor: SEIFERT KEVIN
IPC: H02J50/00
Filed: 2020-12-01
Abstract: Various embodiments of an implantable medical device and a method of implanting such device are disclosed. The device includes a housing having a first major surface, a second major surface, a sidewall that extends between the first major surface and the second major surface, and a port disposed in the sidewall. The sidewall defines a perimeter of the housing. The device further includes an electronic component disposed within the housing, and a cable electrically connected to the electronic component disposed within the housing, where the cable extends through the port. A portion of the cable is adapted to be removably connected to the housing adjacent an outer surface of the sidewall by a fastener such that the portion of the cable extends along at least a portion of the perimeter of the housing when the portion of the cable is removably connected to the housing.
Patent WO-2021126728-A1 (WO)
Title: Prmt5 inhibitors
Inventor: MACHACEK MICHELLE
IPC: A61P35/00
Filed: 2020-12-14
Abstract: The present invention provides a compound of Formula (I) and the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are PRMT5 inhibitors. Also provided are methods of making compounds of Formula I, pharmaceutical compositions comprising compounds of Formula I, and methods of using these compounds to treat cancer, sickle cell, and hereditary persistence of foetal hemoglobin (HPFH) mutations.
Patent WO-2021133696-A1 (WO)
Inventor: SRIDHARAN GOKUL
IPC: H04W92/18
Filed: 2020-12-19
Abstract: Certain aspects of the present disclosure provide techniques for coordinated power savings configurations for access link and sidelink(s). A wireless node may receive information from a user equipment (UE) over a sidelink. In some aspects, the wireless node forwards the information to a base station (BS) over an access link and receives, from the BS, a first power savings configuration for the access link and a second power savings configuration for the sidelink. In some aspects, the wireless node receives, from a BS, a first power savings configuration for an access link and determines a second power savings configuration for the sidelink based on the information and the first power savings configuration.
Patent WO-2021236175-A1 (WO)
Title: Learning illumination from diverse portraits
Inventor: Legendre Chloe
IPC: G06T15/50
Filed: 2020-09-21
Abstract: Techniques of estimating lighting from portraits includes generating a lighting estimate from a single image of a face based on a machine learning (ML) system using multiple bidirectional reflection distribution functions (BRDFs) as a loss function. In some implementations, the ML system is trained using images of faces formed with HDR illumination computed from LDR imagery. The technical solution includes training a lighting estimation model in a supervised manner using a dataset of portraits and their corresponding ground truth illumination.
Patent WO-2021146679-A1 (WO)
Title: Powered bone-graft harvester
Inventor: CONTI STEPHEN
IPC: A61B17/3205
Filed: 2021-01-18
Abstract: A bone graft harvester and method of use are described which produces bone grafts of superior quality to existing techniques. The bone graft harvester is driven in a reciprocating and impacting fashion when placed against bone to be fashioned at a rate of 500 to 20000 impacts per minute and with non-rotating longitudinal movements of 0.5 to 5 mm. Bone is collected in a hollow core of the hollow core coring tool of the bone graft harvester and can be retrieved therefrom for bone grafting procedures. Preferably the hollow core is tapered to allow expansion of the bone in the coring tool so as to better hold bone which is retrieved from the harvesting site.
Patent WO-2021151004-A1 (WO)
Title: Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins
Inventor: ARMOUR SEAN
IPC: A61K39/395
Filed: 2021-01-22
Abstract: Disclosed herein are methods for treating patients that may develop or already have pre-existing gene therapy neutralizing antibodies by administering an agent that blocks, inhibits or reduces the interaction between immunoglobulin G (IgG) and the neonatal Fc receptor (FcRn), such as an anti-FcRn antibody, to reduce IgG recycling and enhance IgG clearance  in vivo . Also disclosed are methods for utilizing agents that reduce interaction of IgG with FcRn for gene therapy treatment of a disease in a patient in need thereof.
Patent WO-2021163627-A1 (WO)
Inventor: COSFORD NICHOLAS D P
IPC: C07D239/70
Filed: 2021-02-12
Abstract: La présente invention concerne des composés, des compositions, des formulations et des méthodes d'utilisation de ceux-ci dans le traitement et la prévention de maladies dont la médiation est assurée par ULK, notamment le cancer.
Patent WO-2021168099-A1 (WO)
Title: Inductive damping brain sensor
Inventor: SHAHRESTANI SHANE S
IPC: G01D5/20
Filed: 2021-02-18
Abstract: Medical diagnostic devices and related methods of use are described in which one or multiple coils in a sensor, each coil connected with an RLC circuit and frequency counter, are held against a patient's head at predetermined cranial locations. Frequencies of the RLC circuit are measured and compared against those taken from known, control heads, to determine whether there is a medical problem and what type of problem. In some instances, too high of frequencies can reveal pooled blood in the head, a sign of hemorrhagic stroke, while too low of frequencies imply lack of blood supply, a sign of ischemic stroke. A head-mountable frame can assist a first responder in securing and guiding the coils and, along with fiducials, allow for automatic comparison of frequencies with the correct control data.