baber/WOPTO huggingface dataset:
Patent DE-69230141-D1 (DE)
Inventor: DICKINSON Roger
IPC: A61K31/4439
Filed: 1992-03-17
Granted: 1999-11-18
Abstract: PCT No. PCT/EP92/00591 Sec. 371 Date Apr. 20, 1994 Sec. 102(e) Date Apr. 20, 1994 PCT Filed Mar. 17, 1992 PCT Pub. No. WO92/17451 PCT Pub. Date Oct. 15, 1992.    <IMAGE>  (I)  Compounds of formula (I) or a biolabile ester thereof, or a pharmaceutically acceptable salt of either, wherein Rl, R2, R3 and R4 are each independently selected from H or C1-C4 alkyl; R5 is (CH2)mSO2R6, (CH2)mNHSO2R6 or (CH2)mNHCOR7; R6 and R7 are C1-C6 alkyl, C1-C3 perfluoroalkyl(CH2)n, C3-C6 cycloalkyl(CH2)n, aryl(CH2)n or heteroaryl(CH2)n; or R6 is NR8R9; R8 is H or C1-C4 alkyl; R9 is C1-C6 alkyl, C3-C6 cycloalkyl(CH2)n, aryl(CH2)n or heteroaryl(CH2)n; or R8 and R9 together with the nitrogen atom to which they are attached form a 5- to 7-membered heterocyclic ring which may optionally incorporate a carbon-carbon double bond or a further hetero atom linkage selected from O, S, NH, N(C1-C4 alkyl) and N(C1-C5 alkanoyl), and which may optionally be substituted with one to three substituents each independently selected from C1-C4 alkyl and C1-C4 alkoxy, and which may optionally be benzo-fused; X is CH2, CHCH3, C(OH)CH3, C=CH2 or O; m is 0 or 1; n is 0, 1, 2 or 3; and Het is 3- or 4-pyridyl or 1-imidazolyl; with the proviso that when Het is 1-imidazolyl then X is CH2 or CHCH3, are combined thromboxane A2 synthetase inhibitors and thromboxane A2/endoperoxide antagonists of utility in the treatment of disease conditions in which thromboxane A2 is a causative agent.
Patent DE-69231068-D1 (DE)
Inventor: MCKENDRY LENNON H
IPC: C07C209/44
Filed: 1992-01-23
Granted: 2000-06-21
Abstract: The present invention is directed to a process for preparing a 2,6-dichloro-4-bromoanilide which is characterized by reacting a 4-bromoanilide with from 1.8 to 2.5 equivalents of chlorine in a solvent consisting of from 3:1 to 100:1 parts of an alkanoic acid per part of water in the presence of from 0.5 to 2.0 equivalents of alkali metal bicarbonate at a temperature between 40 DEG C and the freezing point of the mixture.
Patent DE-69305093-D1 (DE)
Inventor: KEMPF DALE J
IPC: C07C215/18
Filed: 1993-12-16
Granted: 1996-10-31
Abstract: A retroviral protease inhibiting compound of formula (A) is disclosed for use in combination with other active pharmaceutical agents for treating a human infected by HIV. Intermediates and processes useful in the manufacture of compounds of formula (A) are also disclosed. <CHEM>
Patent DE-69313207-D1 (DE)
Inventor: ERICKSON GARY L
IPC: C22C19/05
Filed: 1993-06-23
Granted: 1997-09-25
Abstract: A nickel-based superalloy comprises the following elements in percent by weight: from about 5.0 to about 7.0 percent rhenium, from about 1.8 to about 4.0 percent chromium, from about 1.5 to about 9.0 percent cobalt, from about 7.0 to about 10.0 percent tantalum, from about 3.5 to about 7.5 percent tungsten, from about 5.0 to about 7.0 percent aluminium, from about 0.1 to about 1.2 percent titanium, from about 0 to about 0.5 percent columbium, from about 0.25 to about 2.0 percent molybdenum, from about 0 to about 0.15 percent hafnium, and the balance nickel + incidental impurities, the superalloy having a phasial stability number NV3B less than about 2.10. <IMAGE>
Patent DE-69324389-D1 (DE)
Inventor: MIYAMOTO KATSUHIRO
IPC: G09G3/36
Filed: 1993-01-28
Granted: 1999-05-20
Abstract: The present invention provides a display driving apparatus which can improve a picture quality by smoothly switching a partial writing mode and a refresh driving mode and also provides an information processing system having such a display driving apparatus. When a controller 7 discriminates the partial writing mode by a discrimination signal PH/RL, the controller generates a picture data request signal BUSY to a graphic controller 6, reads out data on a data line PIX DATA, and sets a scan address into a driver controller 12 in accordance with the value of the read data. When the discrimination signal PH/RL is switched from the partial writing mode to the refresh driving mode, in order to restart the refresh driving mode, the controller 7 directly reads a count value of an HSYNC counter 17 and calculates a scan address of the next refresh data in accordance with such a value and sets into the driver controller 12. <IMAGE>
Patent DE-69330852-D1 (DE)
Inventor: SUM PHAIK-ENG
IPC: C07C/
Filed: 1993-05-12
Granted: 2001-11-08
Abstract: The invention provides compounds of the formula: <CHEM> wherein R, R<3>, R<4>, X and W are defined in the specification. These compounds are useful as antibiotic agents.
Patent DE-69334266-D1 (DE)
Inventor: ARTAVANIS-TSAKONAS SPYRIDON DR
IPC: G01N33/574
Filed: 1993-09-30
Granted: 2009-04-23
Abstract: The present invention relates to pharmaceutical compositions comprising a fragment of Serrate protein or a derivative or analog of said fragment, or comprising a derivative or analog of a Serrate protein, or comprising a protein comprising such a fragment, derivative or analog, the fragments, derivatives, analogs and proteins being characterized by the ability  in vitro,  when expressed on the surface of a first cell, to bind to a Notch protein expressed on the surface of a second cell. The invention also relates to chimeric proteins comprising said Serrate fragments joined via a peptide bond to a protein sequence of a protein different from the Serrate protein, and to nucleic acids encoding said fragments of a Serrate protein, and encoding said chimeric proteins. According to the invention, said fragments, derivatives, analogs, and proteins, said chimeric proteins and said nucleic acids may be used as a medicament, for example, in treating or preventing malignancy in a subject.
Patent DE-69411199-D1 (DE)
Inventor: GYORY J
IPC: A61N1/30
Filed: 1994-12-05
Granted: 1998-07-23
Abstract: An apparatus for supplying power to deliver a beneficial agent or drug though a body surface of a patient is provided. In a first embodiment, the invention includes a power supply (eg, a battery 118, 119) and optionally other electrical components (126, 128), positioned in a pocket (114) formed in a supporting substrate (112). Electrically conducting traces (113, 116) positioned on the substrate (112, 113) form an electrical power network connecting the battery (118, 119) to the other electrical components (126, 128), for control and delivery of electrical power. The traces may be electrically conducting adhesive strips (206). In a second embodiment, a waterproof enclosure provides moisture isolation of electrical components in an electrical power network. The waterproof enclosure may be selectively formed around one or a group of electrical components (202, 204, 218) by sealing a sealant film (208, 210). External outputs (207,209) are provided to make electrical contact with closely adjacent electrodes (D, C) at least one of which holds a liquid containing a therapeutic agent.
Patent DE-69420452-D1 (DE)
Inventor: SHOHER ITZHAK
IPC: A61K6/04
Filed: 1994-05-03
Granted: 1999-10-14
Abstract: A moldable dental composition including high-fusing temperature metal particles and a binder comprising wax preferably in a concentration of above at least twenty percent (20%) of the composition. The high-fusing temperature metal particles should have an irregular non-spherical geometry and a thin cross-sectional average thickness. The moldable dental composition may also contain low fusing temperature metal particles for enhanced wetting of the high fusing metal particles during heat treatment at a heat treatment temperature which will substantially melt the low fusing metal particles. However it is not essential to the subject invention for the composition to contain low fusing metal particles.
Patent DE-69424924-D1 (DE)
Inventor: DOELMAN NICOLAAS JAN
IPC: G10K11/178
Filed: 1994-11-22
Granted: 2000-07-20
Abstract: System for the generation of a time variant signal (sec(t)) for suppression of a primary signal (d(t)), comprising: a control unit (1) having a forward filter (10) and/or a feedback filter (11) for providing a cancellation control signal (u(t)); cancellation-generating means (2) for generating a cancellation signal which is propagated along a secondary path with transfer function A/B and then providing the time variant signal (sec(t)),     sensor means (4) for measuring a residual signal ( epsilon (t)), update means (5) for providing an update signal (up(t)) for updating the filter coefficients in the control unit and a prediction filter (8) within the update unit (5), which is intended to generate a predicted value (ypred(t)) which is equal to the anticipated output value of the sensor means (4) at a specific point in time, if the coefficients of the filters (10; 11) had had the most recently obtained values during the entire reaction time of the secondary transfer path. <IMAGE>
Patent DE-69425962-D1 (DE)
Inventor: LUNDBLAD WAYNE
IPC: D03D11/00
Filed: 1994-03-11
Granted: 2000-10-26
Abstract: An article of manufacture that contains a plurality of yarns woven into an interlocking 3-dimensional structure whether or not uniform and symmetrical such that the interlocking impedes the penetration of projectiles such as bullets, fragments, flachettes and the like. The articles of the present invention are useful for providing a high degree of ballistic resistance and are therefore useful in armor applications.
Patent DE-69428370-D1 (DE)
Inventor: DINGSOYR O
IPC: C04B7/52
Filed: 1994-12-07
Granted: 2001-10-25
Abstract: The present invention relates to a cement-based injection grout containing microcement and water for consolidation and/or water proofing fine granular soils, finally fissured soils and cracks in rocks or concrete structures. In addition to microcement and water the grout contains amorphous silica particles in an amount of 5 - 70 % based on the weight of cement and 0 - 10 % water-reducing agents based on the weight of the cement, said grout having a weight ratio between water and cement + amorphous silica between 2 and 8.
Patent DE-69433691-D1 (DE)
Inventor: DAVIS GRAHAM
IPC: G01N33/483
Filed: 1994-09-30
Granted: 2004-05-13
Abstract: The present invention relates to an apparatus for conducting a variety of assays that are responsive to a change in the viscosity of a sample fluid and relates to methods of conducting such assays. In particular, the present invention is related to the use of a cartridge for conducting one or more coagulation assays or, conversely, fibrinolysis assays. The disclosed device enjoys simplicity and is adaptable to the point-of-care clinical diagnostic area, including use in accident sites, emergency rooms, surgery or intensive care units.
Patent DE-69500792-D1 (DE)
Inventor: PEDRINI MAURIZIO
IPC: G09F3/10
Filed: 1995-06-17
Granted: 1997-11-06
Abstract: A label (6) for re-closable packages (1) has an application side (8) on which a layer of self-adhesive glue (20) is spread for application to a surface (7) of a re-closable package (1) to achieve a predetermined adhesive strength. The application side (8) is siliconized in a manner such that the adhesive strength between the side (8) and the layer of self-adhesive glue (20) is less than the predetermined strength. After application, the layer of glue (20) is transferred to the application surface (7), eliminating the risk of tearing of the re-closable package (1). <MATH>
Patent DE-69514646-D1 (DE)
Inventor: UWA MARIAN
IPC: B07B1/22
Filed: 1995-05-05
Granted: 2000-02-24
Abstract: The machine consists of a horizontal or slightly inclined rotary drum (10) made up of a number of sections (10a - 10e) with apertures (26) increasing in size in the direction of the flow through the drum. Each drum section has a truncated conical wall which converges in the direction of the flow, with the apertures in the shape of slots of increasing size in the same direction. Each drum section is in the form of a separate module which can be detached from the adjacent sections, to which it is connected by bolted flanges (14, 16). The end flanges of the first and last drum sections are supported by roller bearings (18, 20). The inside of each drum section has guide vanes, and the slots are inclined relative to the direction of travel.
Patent DE-69515780-D1 (DE)
Inventor: PARENTI GIUSEPPE
IPC: E04H7/20
Filed: 1995-10-10
Granted: 2000-04-27
Abstract: Reinforced concrete panel for the manufacture of aboveground circular tanks, of the type comprising a wall (1) fitted with a number of horizontal stiffening ribs (3) which contain holes for the passage of pre-stressing cables, wherein the said wall is flat and the said holes are arc-shaped, and a method of manufacture of said panels comprising the following stages:   insertion of a flexible tubular element (11), of the same length as an arc which presents a radius equal to the radius of the tank and a chord equal to the width of the panel, into a mould with mobile sides (8,9), on a pair of pegs (10) fitted to the sides at the horizontal ribs (3) of the panel; approach of the mobile sides (8,9) until the mould closes, so that the said flexible tubular element (11) takes on the arc shape required; installation of reinforcement and laying of concrete; concrete shaving; curing and removal of finished product.   <IMAGE>
Patent DE-69529684-D1 (DE)
Title: Adjuvans für impfstoff
Inventor: HAENSLER JEAN
IPC: A61K9/00
Filed: 1995-11-14
Granted: 2003-03-27
Abstract: An amphipathic compound including a sterol-derived lipophilic grouping bound to a cationic grouping for use as an adjuvant in the delivery of a vaccine composition. In a particular embodiment, the lipophilic grouping is a cholesterol derivative and the cationic grouping is a quaternary ammonium or a protonatable amine. A vaccine composition including one or more antigens with at least one amphipathic compound having a sterol-derived lipophilic grouping bound to a cationic grouping, is also disclosed.
Patent DE-69531900-D1 (DE)
Inventor: WURSCH PIERRE
IPC: A23L7/10
Filed: 1995-04-04
Granted: 2003-11-13
Abstract: An extrusion cooked cereal product in ready-to-eat form. The cereal product contains a defatted oat bran concentrate which has a  beta -glucan content of at least 10 % by weight and in an amount so that the cereal product has a  beta -glucan content of at least 5 % by weight. The cereal product in solution providing a viscosity at least as great as the viscosity provided by the components of the cereal product prior to being extrusion cooked. The cereal product is useful in the treatment and prophylaxis of diabetes.
Patent DE-69532092-D1 (DE)
Inventor: ESTULIN WALTER
IPC: H04B1/40
Filed: 1995-07-17
Granted: 2003-12-11
Abstract: A subscriber unit of a time division multiple access (TDMA) radiotelephone system is, from a power consumption standpoint, reconfigured in each time slot of a TDMA frame to a power consumption tessellation in which subscriber unit circuit components not needed for communication signal processing in that time slot are powered down, and other components are powered up.Some circuit components are powered down by switching their power supply circuits. In order to minimize the extent of circuitry that must be provided to distribute power consumption control signals, other techniques (which utilize circuitry provided for other purposes), such as clock frequency control or power down commands, also are utilized to modify controlled circuit component power consumption without actually controlling power supply circuits. Loop connection length between the subscriber unit and the subscriber's telephone set, or other terminal equipment, is limited to a length which is much less than the length of a radio link on which the subscriber unit operates. Programmable ring frequency logic controls the frequency of a ringing signal generator, and a high frequency ring control signal is switched on and off in the cadence of ringing operation. Also an expansion header is provided to enable serving plural subscriber loop circuits with the same radio equipment for reducing per line power consumption.
Patent DE-69604817-D1 (DE)
Inventor: BRAMBACH JOHAN ARIE
IPC: B60P3/22
Filed: 1996-01-26
Granted: 1999-11-25
Abstract: A container (1) for fluids, in particular fluids containing gas, comprises an outer casing (2) of flexible, pressure resistant material, at least a gas and/or fluid tight inner casing (3) of flexible material lying inside the outer casing and being separated therefrom, and at least a filling connection (4) for filling the inner casing. As a result, the container (1) is collapsible so that filling the container may take place from the collapsed condition and filling is therefore possible without pressure difference while the fluid does not enter an empty space. The egress of gas from the fluid is substantially reduced thereby. When fluid is discharged from the container (1), the volume of the container can also decrease by collapsing so that also during use of the fluid gas is prevented from egressing. Consequently, the quality of the fluid is maintained, both during filling of the inner casing with fluid and during discharge of fluid from the inner casing. When the container (1) is completely empty, it is collapsible in a flat manner and occupies only little room, which is very favorable for transport and storage. <IMAGE>
Patent DE-69615985-D1 (DE)
Inventor: MAGYAR GEORGES
IPC: B60P3/22
Filed: 1996-11-15
Granted: 2001-11-22
Abstract: The tank for the thermally insulated transporter vehicle comprises a main cylindrical section (1) forming the base of the tank, and the greater part of the structure of the tank. The cylinder is closed at the end by end plates. The upper section of the tank includes a seating (3) arranged transversely, allowing the installation of indicator lights. The indicator lights may include a central light (4) connected to the vehicle brake lights, and two side lights (5,6) connected to the direction indicators and serving as repeaters. The tank may be covered in an insulation material such as fibreglass (RTM) foam, surrounding a tubular envelope of stainless steel.
Patent DE-69617438-D1 (DE)
Inventor: OSZAJCA HENRI
IPC: G01F1/08
Filed: 1996-08-01
Granted: 2002-01-10
Abstract: A single-jet liquid meter comprises a body in which a measurement chamber of substantially cylindrical shape is disposed. The chamber is fitted with a spinner having a longitudinal axis XX' and provided with blades, a liquid feed tube and a liquid discharge tube connected to the body and in alignment on an axis YY' that intersects axis XX' perpendicularly. A housing is disposed in the body around the periphery of the spinner and includes at least two slots respectively facing the feed tube and the discharge tube. The slots are designed to inject and eject the liquid flow in an inclined manner relative to the alignment axis of the tubes. At least one slot faces the feed tube and presents, to the flow of liquid coming from said tube, a shaped surface that progressively increases the speed of the flow.
Patent DE-69622120-D1 (DE)
Inventor: ALBANO MARGHERITA
IPC: C08F8/00
Filed: 1996-10-17
Granted: 2002-08-08
Abstract: Curing system for fluoroelastomers curable by peroxidic route which comprise iodine comprising as curing agent a bis-olefin having general formula <CHEM>  wherein:   R1, R2, R3, R4, R5, R6, equal to or different from each other, are H or alkyl C1-C5; Z is a linear or branched alkylenic or cycloalkylenic radical C1-C18, optionally containing oxygen atoms, preferably at least partially fluorinated, or a (per)fluoropolyoxyalkylenic radical.
Patent DE-69628150-D1 (DE)
Inventor: MENARD ROBERT
IPC: H04N21/488
Filed: 1996-03-04
Granted: 2003-06-18
Abstract: A system for monitoring standard broadcast signals, comprises a device for receiving the broadcast signals, a user-operable selection device for inputting criteria identifying program content of interest to the user, a database for storing data representing the criteria, and a recognition device for generating from the broadcast signals a program data stream representative of the program content. A comparator compares the program data with the stored data, and an output device carries out a predetermined action, such recording a segment of the program, when the program data matches the stored data. The system will, for example, activate a window on a multimedia PC when preselected program material is present in the broadcast signals.
Patent DE-69628207-D1 (DE)
Inventor: GALAMBOS GEZA
IPC: C07D307/935
Filed: 1996-12-18
Granted: 2003-06-18
Abstract: A process for the preparation of alpha,beta-unsaturated alcohols of general formula (I),whereinR means an alkyl group of 1-4 carbon atoms, or benzoyloxy group optionally substituted with a phenyl group;R1 means a hydrogen atom or an alkyl group of 1-4 carbon atoms,R2 means a hydrogen atom or an alkyl group of 1-4 carbon atoms;R3 means an alkyl group of 1-6 carbon atoms optionally substituted by phenyl group or cycloalkyl group of 5-7 carbon atoms; or a phenoxy group optionally substituted by a halogen atom, or a cycloalkyl group of 5-7 carbon atoms;R4 means a hydrogen atom or a halogen atomwhereby at alpha,beta-unsaturated ketones of general formula (II) wherein themeanings of R, R1, R2, R3, and R4 are as given above-is diastereoselectively reduced with a borohydride type compound in an aprotic solvent, in the presence of an inorganic substance dissolublein the reaction mixture and having particle size from 0.01 micrometer to 10000 micrometer and optionally from the resulting mixture of epimeric alpha,beta-unsaturated alcohols of general formula (I) and (III)meanings of R, R1, R2, R3, and R4 are as given above-the alpha,beta-unsaturated alcohol of general formula (I) is separated by methods known.
Patent DE-69629657-D1 (DE)
Inventor: DENIEGA C
IPC: B01D61/18
Filed: 1996-05-22
Granted: 2003-10-02
Abstract: The method comprises adding to the whole blood, prior to separation, an anticoagulant solution comprising citric acid, trisodium citrate and dextrose and no phosphate, and storing the separated red blood cells in a storage solution comprising dextrose, adenine, mannitol and sodium chloride.
Patent DE-69631525-D1 (DE)
Inventor: CARUSO S
IPC: A61P13/00
Filed: 1996-03-01
Granted: 2004-03-18
Abstract: Urinary incontinence is alleviated in a mammal by administering to the mammal a urinary incontinence alleviating amount of dextromethorphan, dextrorphan, their mixtures and/or pharmaceutically acceptable salts, alone or in combination with a pharmacologically active agent such as an anticholinergic, sympathomimetic, tricyclic antidepressant, antispasmodic, direct-acting smooth muscle relaxant, estrogen, compound having estrogen-like activity, or any combination of the foregoing.
Patent DE-69705319-D1 (DE)
Inventor: ROTH NATHAN
IPC: A61K9/00
Filed: 1997-10-14
Granted: 2001-07-26
Abstract: The present invention is directed to an oral active agent delivery system and method for delivering discrete units of an active agent to a patient. An elongate tubular member having first and second ends comprises first and second flow paths. Either or both of said flow paths contains an active agent. Liquid is drawn up into the first end of the member, and the liquid and active agent is drawn out of the second end of the member and into the patient's mouth.