baber/WOPTO huggingface dataset:
Patent EA-000458-B1 (EA)
Title: Exhaust manifold device
Inventor: VALISKO STEVEN
IPC: F01N3/34
Filed: 1997-01-10
Abstract: 1. An aspirator for allowing air automatically to selectively enter an engine exhaust manifold during operation of an internal combustion engine to inhibit exhaust gases being drawn back into the cylinders via exhaust valves, the aspirator comprising an adapter (10, 11) formed by a hollow body (10) that extends to a port (11) fitted in communication with the manifold (12), a first one way valve (18) fitted to the adapter that prevents gases leaving the manifold through the port (11) when the pressure inside the manifold is greater than the pressure at the first valve, and means for supplying air to a second one way valve (21) at different pressures, above atmospheric pressure, that increase with increases of speed of the engine, characterized in that the second one way valve (21) is connected by a passageway (20) to the first valve forming an intermediate expansion chamber (20'), the second one way valve being arranged to allow air to enter the passageway (20) whenever the pressure inside the passageway (20) is less than the pressure at the second valve (21). 2. An aspirator according to Claim 1, characterized in that the port (11) is formed in a tube that extends somewhat in the manifold (12) beyond its inner surface. 3. An aspirator according to Claim 1 or 2, characterized in that the one way valve (18, 21) each comprises a needle valve. 4. An aspirator according to any Claims 1 to 3, characterized in that the position of the second one way valve (21) is manually adjustable to vary the differential pressure at which the second valve (21) opens and closes. 5. An aspirator according to any Claims 1 to 4, characterized in that the air is supplied to the second one way valve (21) by an air ram having an inlet exposed forwardly in a vehicle in which the engine is mounted so as to provide air at a pressure corresponding to the forward speed of the vehicle. 6. An aspirator according to any Claims 1 to 5, characterized in that the air is supplied by an air pump. 7. An aspirator according to Claim 6, characterized in that the air pump forms part of a turbo charger for the engine. 8. An aspirator according to Claim 1, in which air is supplied to the second valve corresponding to all speeds of the engine.
Patent EA-001032-B1 (EA)
Title: Spherical hydroxyapatite particles and process for the production thereof
Inventor: SHIMP LAWRENCE A
IPC: A61K6/838
Filed: 1997-06-20
Abstract: 1. A process for producing spherical, non-porous hydroxyapatite particles having a size which does not exceed 250 microns, and having a density of at least 3.00 g/cc, comprising: agglomerating in the presence of water as the only additive a hydroxyapatite powder feedstock having a purity of at least 97% and having metallic impurities which do not exceed 500 ppm, to form hydroxyapatite particles having a size which does not exceed 350 microns; drying said hydroxyapatite particles; and sintering said hydroxyapatite particles at a temperature of from about 1,100 degree C to about 1,200 degree C to provide spherical, non-porous hydroxyapatite particles having a size which does not exceed 250 microns and having a density of at least 3.00 g/cc. 2. The process of claim 1 wherein said hydroxyapatite powder has a purity of at least about 98%. 3. The process of claim 1 wherein said hydroxyapatite powder has metallic impurities which do not exceed 350 ppm. 4. The process of claim 3 wherein said hydroxyapatite powder has metallic impurities which do not exceed 300 ppm. 5. The process of claim 1 wherein said spherical non-porous hydroxyapatite particles have a size of from about 75 microns to about 125 microns. 6. The process of claim 1 wherein said spherical hydroxyapatite particles are sintered at a temperature of about 1200 degree C. 7. The process of claim 1 wherein said hydroxyapatite powder feedstock, prior to agglomeration, has an average particle size under 25 microns. 8. The process of claim 1 wherein said spherical non-porous hydroxyapatite particles have a density of at least 3.02 g/cc. 9. Hydroxyapatite particles produced according to the process of claim 1. 10. A process for producing spherical, non-porous hydroxyapatite particles having a size which does not exceed 250 microns, and having a density of at least 3.00 g/cc, comprising: reacting calcium hydroxide having a purity of at least 95%, and having metallic impurities which do not exceed 500 ppm, with phosphoric acid, in the absence of dispersants or surfactants, to provide a hydroxyapatite powder feedstock having a purity of at least 97% and having metallic impurities which do not exceed 500 ppm; agglomerating said hydroxyapatite feedstock in the presence of water as the only additive to form hydroxyapatite particles having a size which does not exceed 350 microns; drying said hydroxyapatite particles; and sintering said hydroxyapatite at a temperature of from about 1,100 degree C to about 1,200 degree C to provide spherical, non-porous hydroxyapatite particles having a size which does not exceed 250 microns and having a density of at least 3.00 g/cc.
Patent EA-010078-B1 (EA)
Title: Medical plaster for application on the skin
Inventor: BRACHT STEFAN
IPC: A61F13/02
Filed: 2005-03-19
Abstract: The invention relates to a medical plaster for application on the skin, wherein the skin-contact surface comprises an adhesive inner area and an outer area which surrounds the inner area. The surface of the outer area lying on the skin is not adhesive. The invention makes it possible to surmount the disadvantages of conventional medical plasters, particularly with regard to the formation of dirt on the edges thereof.
Patent EA-009254-B1 (EA)
Title: Method of manufacturing cobalt catalyst
Inventor: LOK CORNELIS MARTINUS
IPC: B01J23/75
Filed: 2005-05-10
Abstract: A method of manufacturing a cobalt catalyst is described, which comprises the steps of forming an aqueous solution of a cobalt amine complex, oxidising said solution such that the concentration of Co (I11) in the oxidised solution is greater than the concentration of Co (III) in the un- oxidized solution, and then decomposing the cobalt amine complex by heating the solution to a temperature between 80 and 110°C for sufficient time to allow an insoluble cobalt compound to precipitate out of the solution. A catalyst intermediate is also described which comprises a cobalt compound, comprising a Co (II)/Co (III) hydrotalcite phase and a CoOcobalt spine) phase, wherein the ratio of cobalt hydrotalcite phase : cobalt spine phase is less than 0.6:1, said cobalt hydrotalcite phase and said cobalt spine phase being measured by X-ray diffractometry.
Patent EA-013403-B1 (EA)
Title: 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
Inventor: DEANGELIS ALAN
IPC: C07C59/68
Filed: 2005-09-14
Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
Patent EA-023376-B1 (EA)
Title: Solid dosage form and package containing the same for combined therapy
Inventor: ZHU TONG
IPC: A61K9/50
Filed: 2006-04-07
Abstract: A solid dosage form is described herein comprising at least one an active agent which is a salt of 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid with choline and at least one enteric coating. The invention further relates to a package containing said form for combined therapy.
Patent EA-010269-B1 (EA)
Title: Contact assembly on opposed contacts with capillary connecting element and method for manufacturing thereof
Inventor: TARAN ALEXANDER IVANOVICH
IPC: H05K3/46
Filed: 2008-02-14
Abstract: The invention relates to electronic technology, more particular to permanent solded links widely used in manufacturing of articles for use in micro-electronics and semi-conducting devices. A contact assembly is proposed on opposed contacts consisting of two flat contacts connected therebetween by a linking element designed as a crosspiece made from an electroconductive material, wherein each of said contacts is arranged on the surface of one of two coplanar carriers, the - contacts oriented to each other, and clearance between coplanar carriers of the opposed contacts and around the linking element is filled by dielectric material, according to the invention the linking element is made as a capillary with end flanges and filled with electroconducting binding material drawn in said capillary from opposed contacts under the action capillary forces arising at transition binding electroconductive material into liquid state forming mechanically-stable electroconductive connection between the opposed contacts, wherein said capillary is made as an orifice coated by wet electroconductive binding material in plane-parallel plate from dielectric material. There proposed a method of manufacturing contact assembly, in which the height of solder rise in the capillary linking element is determined by the formula:where ρ=8540 kg/m; α = 21×10°C;h – height of molten solder in capillary linking element;γ - coefficient of solder surface tention;θ - angle of solder wettability;α - linear expansion coefficient of solder;ρ– solder density at normal conditions;T– solder temperature in Kelvin degrees at normal conditions;T– temperature of molten solder in Kelvin degrees.
Patent EA-013396-B1 (EA)
Title: Method for preparing oxygen-containing cocktail
Inventor: KALINKIN ANDREY NIKOLAEVICH
IPC: A23L2/38
Filed: 2009-07-01
Abstract: The technical result of the method is aimed at improving cocktail quality and simplification of preparation process. The method for preparing oxygen-containing cocktail is characterized in that drinking water and/or oxygenated water is used for preparing cocktail, the water is poured in an open or closed cavity, an aromatic additive – decoction and/or herbal tincture, and/or syrup, and/or extract, and/or juice concentrate are added, and water mixture with the aromatic additive is prepared, a foaming agent may comprise dry chicken egg white and/or gelatin, and/or licorice root, and/or pectin, and/or treacle, and/or soap root, and/or extraction of marine algae and added in said mixture – or the aromatic additive with the foaming agent as a finished mixture are added simultaneously to the cavity, wherein for preparing 1 liter of cocktail the following ingredients are added to the cavity: the aromatic additive – 1-39 ml; the foaming agent – 0.1-10 ml; water – 97.9-51 ml; water is oxygenated prior to adding thereof to the cavity or at the moment of its adding to the cavity or after that, water is oxygenated within 1-62 ml of oxygen content per 1 liter, mixing the obtained mixture simultaneously with its bubbling or mixing a mixture by bubbling and add oxygen to the mixture, or mixing the mixture by oxygenated water, wherein the cocktail mixture is mixed until its volume is increased by 1.5-20 times exceeding its rated volume equal to the sum of all said cocktail ingredients before their mixing in the cavity.
Patent EA-022066-B1 (EA)
Title: Agomelatine hydrobromide hydrate and preparation thereof
Inventor: SHAN HANBIN
IPC: C07C233/18
Filed: 2011-03-17
Abstract: The present invention relates to an agomelatine hydrobromide hydrate of formula Iwherein X is Br, preparation and use thereof, and to a pharmaceutical composition containing it. The agomelatine hydrobromide hydrate obtained by the present method has significant increased solubility than agomelatine, and therefore is more suitable for manufacturing pharmaceutical formulations. In addition, the product has higher stability and purity. Using the present method, a product of high purity can be obtained through a simple process, free of any complicated steps.
Patent EA-021237-B1 (EA)
Title: Benzamide derivatives and their use as hsp90 inhibitors
Inventor: DONALD ALASTAIR DAVID GRAHAM
IPC: C07D211/58
Filed: 2011-06-10
Abstract: The invention provides a compound which is: (a) a phenylamide derivative of formula (I) or a tautomer thereof, or (b) a pharmaceutically acceptable salt, hydrate or solvate thereofwherein R, R, R, R, R, Rand Rare defined herein. The compounds are useful in the treatment of diseases mediated by HSP90.
Patent EA-023446-B1 (EA)
Title: METHOD FOR PREPARING AN ENRICHED IgG COMPOSITION FROM PLASMA
Inventor: BRUCKSCHWAIGER LEOPOLD
IPC: A61K35/16
Filed: 2010-05-27
Abstract: The invention relates to the sphere of manufacturing immunoglobulin products for intravenous administration. Disclosed is a method for preparing an enriched IgG composition from cryo-poor plasma, the method comprising the steps of precipitating a cryo-poor plasmid fraction, in a first precipitation step, with alcohol to obtain a first precipitate and a first supernatant comprising IgG; precipitating IgG from the first supernatant, in a second precipitation step, with alcohol to form a second precipitate comprising IgG; re-suspending the second precipitate in an extraction buffer to form a suspension; precipitating IgG from said suspension with alcohol to form a third precipitate comprising IgG; re-suspending the third precipitate in an aqueous solution to form a suspension having a soluble fraction comprising IgG and an unsoluble fraction; and separating the soluble fraction from said suspension, thereby forming an enriched IgG composition, wherein at least one of the first precipitation step, second precipitation step, or third precipitation step comprises spray addition of the alcohol. The invention may be used for improving the methods for manufacturing immunoglobulin products for intravenous administration.
Patent EA-024452-B1 (EA)
Title: Anticancer fusion protein
Inventor: PIECZYKOLAN JERZY SZCZEPAN
IPC: C12N15/62
Filed: 2011-12-05
Abstract: A fusion protein comprising domain (a) which is a functional fragment of hTRAIL protein sequence, which fragment begins with an amino acid at a position not lower than hTRAIL95, or a homolog of said functional fragment having at least 70% sequence identity; and domain (b) which is a sequence of an immunostimulating effector peptide, wherein the sequence of domain (b) is attached at the C-terminus or N-terminus of domain (a). The fusion protein can be used for the treatment of cancer diseases.
Patent EA-031301-B1 (EA)
Title: D-amino acid chemical compounds for treating liver diseases
Inventor: MAYES BENJAMIN ALEXANDER
IPC: C07H19/20
Filed: 2013-05-21
Abstract: Provided herein are chemical compounds, compositions and methods for the treatment of liver disease and conditions, including HCV infections, represented by formulaor a pharmaceutically acceptable salt, wherein the base isa tautomeric form thereof, wherein Rhydrogen, halogen or methyl; and Ris ethyl, propyl, isopropyl, n-propyl, butyl, n-butyl, tert-butyl, cyclopentyl or benzyl. In certain embodiments, chemical compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other antiviral agents.
Patent EA-027948-B1 (EA)
Title: Cosmetic formulation for preparing sun protection agents
Inventor: STAFFEL THOMAS
IPC: A61Q17/04
Filed: 2013-01-12
Abstract: The present invention concerns a cosmetic formulation for preparing sun protection agents comprising a linear potassium polyphosphate and/or sodium polyphosphate with a chain length of 8-15 and at least one paraben.
Patent EA-028283-B1 (EA)
Title: Method for tamping a railroad track by means of an asynchronously moved tamping unit
Inventor: SPRINGER HEINZ
IPC: E01B27/16
Filed: 2013-10-01
Abstract: For tamping two adjacent sleepers (9) of a track (3), the joint lowering of two adjoining tamping units (2) takes place with a time delay. As a result, the immersion in particular of immediately adjacent inner tamping tines (20) plunging into a common sleeper crib (18) is facilitated.
Patent EA-031689-B1 (EA)
Title: Method for producing cathode copper
Inventor: JAATINEN AKUSTI
IPC: C22B15/00
Filed: 2015-04-16
Abstract: The invention relates to a method for producing cathode copper. The method comprises a smelting step including feeding sulfidic copper bearing material (1; 1a, 1b) and oxygen-bearing reaction gas (2) into a suspension smelting furnace (5; 5a, 5b), to produce blister copper (7), a fire refining step including feeding blister copper (7) into an anode furnace (12) to produce molten anode copper (13), an anode casting step to produce cast anodes (15), a quality checking step (16) for dividing cast anodes (15) into accepted cast anodes (17) and rejected cast anodes (18), an electrolytic refining step including subjecting accepted cast anodes (17) to electrolytic refining in an electrolytic cell (19) to produce cathode copper (20) and as a by-product, spent cast anodes (21), and a recycling step for recycling anode copper of rejected cast anodes (21).
Patent EA-029775-B1 (EA)
Title: Use of a 1,3,5-triazin-2-yl phosphoramidate compound in the synthesis of sofosbuvir
Inventor: STEFKO MARTIN
IPC: C07F9/6558
Filed: 2015-04-15
Abstract: The present invention relates to a new type of 1,3,5-triazin-2-yl phosphoramidates of general formula I with the absolute configuration (S) at the phosphorus atom, an Sp diastereoisomer, wherein Rand Rcan independently be H, a C1-C6 (un)branched alkyl, a C1-C6 (un)branched alkoxy group, a C1-C6 (un)branched alkylsulfanyl group, C1-C6 (un)branched monoalkylamino or dialkylamino group, including cyclic amino groups, e.g. pyrrolidino, piperidino or morpholino group; and to their use for the production of biologically active phosphoramidate prodrugs, especially sofosbuvir of formula II. Sofosbuvir II is a nucleotide inhibitor of the RNA polymerase, used for the treatment of hepatitis C in the form of a prodrug, releasing the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate in the organism.
Patent EA-033360-B1 (EA)
Title: Bridge with lug supports
Inventor: ZINKOVA VIKTORIA ANATOLIEVNA
IPC: E01D19/02
Filed: 2017-11-02
Abstract: The proposed invention relates to the field of construction, namely to the construction of bridges, and can be utilized in the structures of bridges across mountain rivers to overarch wide spans. The goal of the invention is to create a reliable bridge structure with an increased crossing power and low material consumption due to its improved bearing capabilities. The task is solved by including a superstructure with consoles and lug supports in the structure of the bridge with lug supports. In the method proposed the consoles are set on traverses that rest on lug supports constructed on the bank, each such support shaped as a rectangular slanted triangular truss with pillars. The right angle of the truss is facing the transverses and its lower belt is directed from the bank to the middle of the river. Together with the central pillar, the trusses are rigidly fixed in the foundation plate and connected by a horizontal rod with the buried plate. At its upper part the central stand is connected with an inclined stand fixed in the buried plate.
Patent EA-035709-B1 (EA)
Title: Pharmaceutical composition for improving or preventing progression of chronic kidney disease
Inventor: SINGH ANKIT SHYAM
IPC: A61P13/12
Filed: 2018-08-31
Abstract: The present invention relates to a pharmaceutical composition/formulation for improving or preventing progression of chronic kidney disease (CKD) caused due to inflammation and/or klotho under expression. More particularly, the invention relates to a composition/formulation comprising a synergistic combination of palmitoylethanolamide (PEA), cholecalciferol and one or more natural ingredients. The invention also provides various formulations and methods of preparing the same.
Patent EA-035017-B1 (EA)
Title: Method to radiographically determine geometrical parameters and/or substance state of an object under study
Inventor: TELEKI PETER
IPC: G06T7/10
Filed: 2017-07-27
Abstract: The invention relates to a method to determine geometrical parameters of an object under study by radiography, the object can be described geometrically. Intercepts that go through the material of the object under study can be determined from a projection of the object - e.g. a tube - imaged by an X- or gamma-radiation source if exposition data of the radiographic image are available. These intercepts that go through the material of the object - i.e. the intercept curves - allow that the object under study - e.g. the tube - have a dimension that is larger than the dimension of the device (film/detector) used to take the radiographic image. During the course of said method, the source of radiation, the object under study and the device (film/detector) used to take the radiographic image are in fixed positions.
Patent EA-038579-B1 (EA)
Title: Improved process for preparing imetelstat
Inventor: MUSLEHIDDINOGLU JALE
Filed: 2018-07-09
Abstract: The invention relates to a process for preparing the telomerase inhibitor imetelstat using a 3 steps per cycle solid-phase support bound process comprising the steps of deprotection of the 3'-amino group of the support-bound oligonucleotide, coupling with a 5'-phosphoramidite, and sulfurization with an acyl disulfide, characterized by the absence of an additional capping step in each cycle that is used to prevent unreacted 3'-amino oligonucleotide groups from reacting during subsequent cycles. Imetelstat has formula below.
Patent EA-037968-B1 (EA)
Title: Pneumatic cushions for soft reception of harvested fruit on mechanized fruit harvesting device
Inventor: KOKANOVIC MOMCILO
IPC: A01D46/28
Filed: 2018-07-02
Abstract: The invention relates to pneumatic cushions for soft reception of harvested fruit on a mechanized fruit harvester, in order to cushion the fall of harvested fruit wherein the assembly (3) consists of a plastic reception tray (4) and a rubber membrane (5), and the whole assembly (3) has a polygonal shape. The rubber membrane (5), which is most favourably made of food-grade rubber, is stretched over the upper side of the reception tray (4) and the side edges of the tray (4), and attached to the side surfaces of the tray (4). The membrane (5) is glued around the entire side perimeter of the tray (4) and secured by means of a safety tape (6). On the part opposite to sides (c, d), on the bottom of the tray (4), are fitted blow-holes (7) for release of air from underneath the membrane (5). On the corner of the tray (4), formed by sides (a, e), is fitted a mechanism (10) for revolving connection of the tray (4) to the support (23) and to air supply pipes (20), wherein the mechanism (10) includes an axle (12) and a bushing (13) with a hole (14).
Patent EA-039145-B1 (EA)
Title: Trigger mechanism
Inventor: ROUSSEAU RANDY
IPC: A62C13/70
Filed: 2015-06-22
Abstract: Improvements to a portable fire extinguisher are disclosed. The improvements allow for frequent and simplified inspection and maintenance of a fire extinguisher with minimal training and without need for custom equipment. The improvements include an anti-bridging mechanism that can be articulated from the exterior of the chamber to fluff, mix or stir the powder within the chamber to keep it in a liquefied state. Additional improvements include a larger opening to more quickly fill the chamber with the powder and simplify inspection of the condition of the powder within the chamber. Another improvement includes the use of a CO2 cartridge located external to the chamber to allow easier servicing or replacement of the CO2 cartridge as well as the ability to maintain the chamber in an un-pressurized condition, that allows for non-HASMAT shipping. These features will extend the service intervals while maintaining the fire extinguisher in a ready condition.
Patent ES-2173784-B1 (ES)
Title: Empaquetadora de estuches de huevos.
Inventor: DE LA ENCINA JIMENEZ JOSE ANTO
IPC: B65B23/08
Filed: 2000-01-03
Granted: 2003-10-01
Abstract: Empaquetadora de estuches de huevos que consiste en una cinta transportadora (1) por la cual se desplazan superpuestos, disponiendo de unas guías (3) y un brazo articulado (4), que actúa sobre un recubrimiento laminar de cartón (5), disponiendo de ventosas (7) y contando con guías metálicas paralelas (8), así como de un mecanismo (9), realizándose la unión del elemento laminar (5) incorporando los estuches de huevos en su interior.