baber/WOPTO huggingface dataset:
Patent CA-2499896-A1 (CA)
Title: Hepatocyte growth factor variants
Inventor: PEEK MARK D
IPC: A61K38/18
Filed: 2003-10-03
Abstract: Serine proteases factor XIa and kallikrein cleave and activate HGF. Cleavage is at two sites: a typical cleavage site, Arg494-Val495, and a novel cleavag e site, Arg424-His425. Variant HGF fragments obtained by cleaving at one or bo th of these sites may be useful as agonists or antagonists of HGF. Variants or fragments obtained by modifying these cleavage sites so as to be resistant t o kallikrein and/or FXIa cleavage are also provided.
Patent CA-2502174-A1 (CA)
Inventor: ZHOU CHANGYOU
IPC: C07D498/04
Filed: 2003-10-24
Abstract: La présente invention concerne des composés représentés par la formule générale (I). Dans cette formule, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿, R?8¿, R?9¿, R?10¿, R?11¿, R?27¿, R?28¿, R?29¿, R?30¿, R?31¿, X, m, n et la ligne en pointillés sont tels que définis dans les spécifications. Ces composés conviennent particulièrement comme modulateurs de l'activité des récepteurs de la chimiokine et plus particulièrement du récepteur CCR-2.
Patent CA-2504624-A1 (CA)
Inventor: FINK YOEL
IPC: G02B6/02
Filed: 2003-12-10
Abstract: In general, in one aspect, the invention features an article including a high-power, low-loss fiber waveguide (100) that includes alternating layers of different dielectric materials (130, 140) surrounding a core (120) extending along a waveguide axis (199), the different dielectric materials including a polymer (130) and glass (140).
Patent CA-2505469-A1 (CA)
Inventor: CARTER ANDREW J
IPC: A61K31/436
Filed: 2005-04-27
Abstract: There is provided herein a drug delivery device comprising an intraluminal medical device, the intraluminal medical device including a stent having a fenestrated structure, the stent comprising a plurality of bands and links defining a substantially tubular device with openings. The device further comprises a polymeric coating affixed to the bands and links of the fenestrated structure, the polymeric coating having first and second layers; and a therapeutic dosage of rapamycin incorporated into the polymeric coating for treatment of intimil hyperplasia, constrictive vascular remodeling, and inflammation caused by injury. The rapamycin is incorporated into the first layer of the polymeric coating, the first layer comprising a solution of ethylene-co-vinylacetate and polybutylmethacrylate. The second layer, comprising polybutylmethacrylate, acts as a diffusion layer. The first layer has a thickness in the range from about eight microns to about twelve microns and the second layer has a thickness in the range from about one micron to about two microns, the rapamycin being configured for release over a period of about seven to thirty days and having a dosage in the range from about 35 to 430 micrograms per 15 to 18 mm length stents thereby producing a peak 50 to 55 percent reduction in neointimal hyperplasia of about 175 micrograms for a 3.5 mm by 18 mm stent.
Patent CA-2505771-A1 (CA)
Inventor: WANG PEI-RAN
IPC: A61K31/216
Filed: 2003-12-09
Abstract: The invention relates to a combination which comprises a DPP-IV inhibitor and at least one further PPAR.alpha. compound, preferably selected from the group consisting of fenofibrate, micronized fenofibrate, bezafibrate, gemfibrazil and ciprofibrate for simultaneous, separate or sequential use in the prevention, delay of progression or treatment of conditions mediated by DPP-IV  and PPAR.alpha., in particular diabetes, more especially type 2 diabetes mellitus, conditions of IGT, conditions of impaired fasting plasma glucose, metabolic acidosis, ketosis, arthritis, obesity, dyslipidemia and osteoporosis.
Patent CA-2507280-A1 (CA)
Inventor: MATHIEU ALFRED L
IPC: B64C15/14
Filed: 2005-05-24
Abstract: 1. A transport plane with 2 (or 4) primary jet engines-under-the-wing is supplemented by a smaller proficient "Auxiliary" jet engine installed on each side of the rear fuselage that has the mechanical and technological capability to rotate 180 degrees for Horizontal Short Take Off and Landing (H/STOL) capability. The exhaust thrust of the "Auxiliary" jet engines rotated to the front on landing serves as a direct and efficient braking mechanism for the jet plane to stop on a short runway and also to effectively "backup" the plane to its setting and there, expeditiously load or unload its cargo of either peace keeping military troops and equipment or humanitarian aid. The two "Auxiliary" jet engines are independent and have separate controls for rotatability, have their own fuel supply and electrical system with the pilot able to shift essential flight controls and thrust of the plane to the "Auxiliary" jet engines on "standard mode" either during high altitude flying to conserve fuel or in the event of an emergency, have sufficient power for the pilot to land the plane and its cargo safely.     The invention is applicable to private and commercial jet planes.
Patent CA-2508908-A1 (CA)
Title: Package wrapping machine with self-centering film support system
Inventor: WATSON JAN M
IPC: B65B41/16
Filed: 2005-05-31
Abstract: A wrapping or other packaging machine includes a support for rolled film or other media and roll edge guides with an associated adjustment system adapted to facilitate proper positioning of different widths of rolled media on the support.
Patent CA-2515050-A1 (CA)
Title: Mailer package
Inventor: OSNATO JEFFREY S
IPC: B65D5/42
Filed: 2004-02-04
Abstract: A mailer package (110) formed from a single sheet blank (112) of foldable stock material includes at least one panel (Kuchenbecker) having first and second sides (118', 120'). A closure flap (156) with a tearable pull tab (158) extends from a first edge (119') of the one panel. A compartment flap (122) extends from a second edge (121') and includes an attachment tab (126). The compartment flap forms a compartment (116) having four sequentially adjoining sides (132, 134, 136, Kuchenbecker), formed by folds (121, 127, 129, 131). The compartment has first and second open ends (128, 130), closed by tabs (140, 146, 148) and a cover (114) extending from a third edge (123') of the one panel.
Patent CA-2516300-A1 (CA)
Title: Hydrogen recycle for high temperature fuel cells
Inventor: BABICKI MATTHEW L
IPC: H01M8/12
Filed: 2004-02-26
Abstract: High temperature fuel cell electrical generation systems are provided that are adapted to enable selective generation of electrical power, and/or hydrogen fuel, and/or useable heat, allowing flexible operation of the generation system. In such embodiments, the high temperature fuel cell may be either a MCFC or a SOFC. The disclosed systems relate to high temperature fuel cells exploiting gas separation devices in which a first gas mixture is to be separated so that a first product of the separation is enriched in a first component, while a second component is mixed with a displacement purge stream to form a second gas mixture, with provision to prevent cross contamination of purge gas components into the first product stream. The invention may be applied to hydrogen (component A) enrichment from syngas mixtures such as fuel cell anode exhaust, where dilute carbon dioxide (component B) is to be rejected such as to the atmosphere or for recycle to the fuel cell cathode in the case of molten carbonate fuel cells, by purging with cathode exhaust oxygen-depleted air (as component C).
Patent CA-2518513-A1 (CA)
Title: N-alkyl-hydroxamic acid-isoindolyl compounds and their pharmaceutical uses
Inventor: MULLER GEORGE W
IPC: C07D209/46
Filed: 2004-03-12
Abstract: The invention encompasses novel N-alkyl-hydroxamic acid-isoindolyl compounds of formula (I) with the definition X1-X4, Z1, Z2, R1, R2, R7 and Y according to claim 1, pharmaceutical compositions of these compounds, and methods of using these compounds and compositions for treatment or prevention of various diseases and disorders mediated by PDE4 inhibition, associated with abnormal TNA-alpha levels, and/or mediated by MMP inhibition.
Patent CA-2520441-A1 (CA)
Inventor: BENATO PIERRE
IPC: G06K19/077
Filed: 2004-03-26
Abstract: Procédé de fabrication d'antenne de carte a puce hybride contact-sans contac t ou sans contact qui comprend un support 10, 11 sur lequel est réalisée l'antenne, deux corps de carte 32, 42, 34, 44 de chaque côté du support, chacun des corps de carte étant constitué d'au moins une couche de thermoplastique, et d'une puce 30 ou d'un module connecté à l'antenne. Ce procédé comporte les étapes suivantes - une étape de dépôt d'une couche d'un matériau composé majoritairement de résine sur une zone prédéterminée 12, 13 du support d'antenne, - une étape de fabrication de l'antenne consistant à sérigraphier des spires 14, 15 et deux plots 16, 18, 17, 19 de connexion d'encre polymère conductrice sur la zone réalisée préalablement sur le suppo rt et à faire subir un traitement thermique au support afin de cuire l'encre.</ SDOAB>
Patent CA-2520541-A1 (CA)
Title: Antisense oligonucleotides (odn) against smad7 and uses thereof in medical field
Inventor: MONTELEONE GIOVANNI
IPC: A61K38/00
Filed: 2004-03-08
Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn~s disease and ulcerative colitis.
Patent CA-2520548-A1 (CA)
Inventor: MASTROBATTISTA ENRICO
IPC: C40B50/08
Filed: 2004-03-31
Abstract: The invention describes a method for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, comprising the steps of: a) compartmentalising the compounds int o microcapsules together with the target, such that only a subset of the repertoire is represented in multiple copies in any one microcapsule; and b) identifying the compound which binds to or modulates the activity of the target. The invention enables the screening of large repertoires of molecule s which can serve as leads for drug development.
Patent CA-2520984-A1 (CA)
Title: Center-of-gravity tilt-in-space wheelchair
Inventor: KILLEBREW ALLEN B
IPC: A61G5/04
Filed: 2004-03-31
Abstract: A center-of-gravity tilt-in-space wheelchair (10) includes a base (12), a seat assembly (14) for supporting an occupant, and tracks (46) supporting the seat assembly (14) for selective seat movement relative to the base (12). Wheels (16, 18) are adapted to support the base (12) relative to a supporting surface. The tracks (46) serve as rolling or sliding surfaces that allow the seat assembly (14) to rotate with respect to the base (12). Each track (46) has a constant-radius arc (A) with a focal point (P) that is adapted to be coincident with the center of gravity (CG) of the wheelchair occupant. A low-friction support (50) supports the base (12) relative to the seat assembly (14). The low-friction support (50) may include low friction elements that mate with the tracks (46) to support for the tracks (46). The support (50) can be adjustable to permit the overall tilt angle range of the tracks (46) to be adjusted. The wheelchair seat assembly (14) can be adjusted to maintain the focal point (P) of the constant-radius arc (A) of the tracks (46) coincident with the center of gravity of the wheelchair occupant. The front and rear wheels (16, 18) can be adjusted fore and aft relative to the focal point (P).  A coupling (74) includes plates having upper ends operatively attached to one another with seat canes (62) therebetween and lower ends releasably attached relative to the side tubes (44). The lower ends can be movable in a longitudinal direction relative to the side tubes (44) while remaining operatively connected to the side tubes (44). A base frame can include side tubes (40) having an offset (182) at a front end and a caster housing (52) supported by the offset (182). The offset (182) is directed up to minimize the height of the side tubes (40) and down to maximize the height.
Patent CA-2522255-A1 (CA)
Inventor: BRIGGS SARAH ELIZABETH
IPC: G06F9/40
Filed: 2004-04-08
Abstract: This invention relates to a computer system, in particular to a computer system having a plurality of components which can be initialised. There is provided a computer system having a plurality of components that can be initialised, wherein each component is configured to produce status data from which the level of need for that component to be initialised can be inferred.  At least one component is configured to: receive status data from other components; make a comparison using the status data received from respective components; in dependence on the comparison, select one or more components for initialisation; and, issue initialisation instructions to the selected component(s). By making a comparison between the status data from different components, the relative need for different components to be initialised can be evaluated, allowing a component with a high need for initialisation to be selected over a component with a lower need.
Patent CA-2523596-A1 (CA)
Inventor: KOPRIAN ALEXANDER
IPC: H02H9/00
Filed: 2004-04-29
Abstract: The invention relates to a power supply unit (5) for a measuring apparatus (1) for determining and/or monitoring a physical or chemical process variable of a medium. According to the invention, at least one voltage limiting unit (10) and/or at least one current limiting unit (15) is provided in the power supply unit (5), wherein the voltage limiting unit (10) is configured in such a way that the voltages produced remain under a given value that leads to an explosion in an explosion-endangered area and wherein the current limiting unit (15) is configured in such a way that the currents produced and/or the heatings linked thereto remain under a given value that leads to an explosion in an explosion-endangered area.
Patent CA-2524752-A1 (CA)
Title: Expandable stent having a stabilized portion
Inventor: JONES DONALD K
IPC: A61F2/84
Filed: 2005-10-27
Abstract: An expandable stent having a covering which exhibits the characteristic of being normally dissolvable in blood, but upon being activated, becomes inert to blood. The stent may be placed across the neck of an aneurysm to seal the aneurysm and thereafter the portion of the covering of the stent across the neck of the aneurysm is activated to become inert to blood and the balance of the covering dissolves to permit blood to flow to adjacent vessels.
Patent CA-2526972-A1 (CA)
Inventor: HAMMOND ERNEST KENNETH
IPC: B29C44/12
Filed: 2003-05-30
Abstract: A method of making a moulded component (for example a door) comprises placin g a core (1) comprising at least one slab of foam material into one half of a mould (4,5)with LPSMC (2), closing the mould and applying pressure and heat to render the LPSMC fluid to at least partially envelop the core (1) and thereb y produce a LPSMC coated component, wherein the core has at least one cavity ( 6) which extends across the width thereof and which has at least a portion whic h is inboard of the intended outer edge (10) of the component, whereby causing the LPSMC to flow into said at least one cavity (6) to form a bridge between the sides of the so-formed component. The foam material may have a portion with a density in excess of 250 kgm<sp>-3</sp>. The core may com prise two slabs of material with a density in excess of 250 kgm <sp>-3</sp> ;either side of a lower-density core material.
Patent CA-2528019-A1 (CA)
Inventor: DESAI PRATIK
IPC: G10L15/00
Filed: 2004-06-09
Abstract: Speech input (404) is received and processed (406-414) for storage (416). The resulting models may be transmitted for use in communications devices (418) such as cellular telephones. The recognized speech may be used to generate some desired actions within the network (420).
Patent CA-2529606-A1 (CA)
Inventor: VORA AAKANKSHA HARSHAD
IPC: A61K9/20
Filed: 2004-07-09
Abstract: The present invention provides a pharmaceutical composition comprising a drug and polyethylene glycol, wherein the ratio of polyethylene glycol to drug by weight is from about 0.2:1 to about 10:1, and the polyethylene glycol has a melting point of at least 37oC. The pharmaceutical compositions of the invention exhibit rapid dissolution upon contact with physiological solvents, such as water, saliva or gastrointestinal fluids.
Patent CA-2535315-A1 (CA)
Inventor: MIJIRITSKII ANDREI
IPC: G11B7/24079
Filed: 2004-08-12
Abstract: A recordable optical record carrier is provided comprising a recording dye layer, whereby said recording dye layer (111) comprises at least two organic dye materials being absorptive at different wavelengths. Further, a method for writing on such a recordable optical record carrier is proposed. According to the method marks representing the data are written via a writing laser beam at a first predetermined wavelength according to a writing strategy providing a channel bit length and a mark width appropriate for read-out by a beam of electromagnetic radiation at a second predetermined wavelength being different from said first predetermined wavelength.
Patent CA-2538674-A1 (CA)
Title: Belt cleaner
Inventor: UCHIDA MASAHIRO
IPC: B65G45/16
Filed: 2006-03-07
Abstract: A belt cleaner device is provided in which assembling of a frame and a cleaner head may be performed easily and quickly. A belt cleaner device comprises a frame 3 and one or more cleaner heads 1. The frame 3 includes a support face (3a) on its upper surface, and a support hole (33) through the frame. The cleaner head (1) includes a contact face (14) on its undersurface, and an anchor (16) projecting downward from the contact face (14). The cleaner head (1) is supported so as not to be rotated about the running direction of the belt by contacting the contact face (14) and the support face (3a) with each other. The cleaner head (1) is fixed to the frame (3) by fixedly inserting the anchor (16) in the support hole (33). The cleaner head (1) further provides a concave (21) in at least one of the front and rear walls (13) (15) to form a strike seat (22) at the bottom of the concave (21). The strike seat (22) is struck with a hammer or the like so that the anchor (16) is pressed and inserted in the support hole (33).
Patent CA-2539145-A1 (CA)
Title: Method and apparatus for automatic calibration of a touch monitor
Inventor: STUDT PETER C
IPC: G06F3/041
Filed: 2006-03-09
Abstract: A method and apparatus for associating components within a touch monitor (150) comprising a monitor (154) and a touchscreen (158) which are interconnected with one another. A first data value is stored in a memory (168) interconnected with the monitor, and a second data value is stored in the memory (180) which is interconnected with the touchscreen. The first and second data values are used to identify a unique relationship between the monitor and the touchscreen. When the first and second data values are read and compared, it is determined whether the monitor and the touchscreen are associated with one another based on the first and second data values.
Patent CA-2541285-A1 (CA)
Inventor: KAINE MICHEL
IPC: H01R13/52
Filed: 2006-03-30
Abstract: A rocket for use with an electrical connector. The rocket is made of suitable resilient material and is used to seal a port through which a conductor passes to connect to the connector. The rocket has a tubular base section that snugly fits within the port, and a longer, tapered, tubular, sealing section extending from one end of the base section. The sealing section is cut through along a line transverse to its longitudinal axis at a location on the section to provide an opening through which a conductor of a specific size, relative to the opening, can pass while expanding a portion of the sealing section adjacent the opening so as to tightly seal it against the conductor.
Patent CA-2542869-A1 (CA)
Title: Ion mobility tof/maldi/ms using drift cell alternating high and low electrical field regions
Inventor: UGAROV MICHAEL V
IPC: G01N/
Filed: 2004-10-20
Abstract: Improved ion focusing for an ion mobility drift cell allows for improved throughput for subsequent detection such as mass detection. Improved focusing is realized by the use of alternating regions of high and low electric fields in the ion mobility drift cell.
Patent CA-2543111-A1 (CA)
Title: Aluminum conductor composite core reinforced cable and method of manufacture
Inventor: HIEL CLEMENT
IPC: D04H3/08
Filed: 2004-10-22
Abstract: This invention relates to an aluminum conductor composite core reinforced cable (ACCC) and method of manufacture. An ACCC cable (300) has a composite core surrounded by an outer film (305) and at least one layer of aluminum conductor (306). The composite core (303) comprises a plurality of fibers from at least one fiber type in one or more matrix materials. According to the invention, unique processing techniques such a B-Staging and / or film-coating techniques can be used to increase production rates from a few feet per minute to sixty or more feet per minute.
Patent CA-2544402-A1 (CA)
Inventor: LAPSLIE KAREN ANN
IPC: B30B9/28
Filed: 2006-04-26
Abstract: Hand-Mate Centre Align-ment is a mechanical machine ( device ), of component parts which co-ordinate together to-capture, utilize and harness power, energy and force from the center axis points of connection (a straight line joining the two points is bisected by the original point) and then distributes balance of that harnessed power, energy and force by pressure motion uniformly across horizontal and vertical planes to their axis points of each line, which in turn will control balance and weight with ease where the mechanical component parts, will operate together in a straight line that enhances a direct line under pressure, placing horizontal and vertical alignment with a center point beginning and, its recoil fully under control by the manual operational leverage with no vibration on connecting dies or in the recoil positions.
Patent CA-2546748-A1 (CA)
Inventor: GRAYBEAL MICHAEL
IPC: F16L15/04
Filed: 2006-05-12
Abstract: The present invention includes an adaptive slip joint coupling for connecting a fixture exit pipe to a wall pipe and also includes a system of couplings of varying dimensions, both providing for adaptable connections.
Patent CA-2546800-A1 (CA)
Inventor: SPITLER ALEXANDRA LYNNE MATTHE
IPC: H01R12/71
Filed: 2004-11-17
Abstract: A header assembly (200) includes an insulative housing (100) comprising a plurality of walls defining an interior cavity (108), and a plurality of contacts (150, 170) within said cavity and extending through one of the walls to an exterior of the housing for surface mounting to a circuit board. The insulating housing (100) comprises at least one alignment rib (136) extending on an exterior surface thereof. The contacts are formed to abut the alignment rib, thereby ensuring coplanarity of the contacts for surface mounting to a circuit board.
Patent CA-2547045-A1 (CA)
Inventor: SCHULAT JOCHEN
IPC: A61B5/15
Filed: 2006-05-16
Abstract: The invention relates to a portable analysis appliance (10) with an interior delimited by a housing (12, 14), and with a magazine (26, 78) for holding test elements (42). A delivery device (32, 34, 36) is provided for delivering the test elements (42) from a first position in the interior of the magazine (26, 78) to a second position lying at least partially outside the magazine (26, 78) and inside the housing (12, 14), the delivery of the test elements (42) taking place in two movements. From the magazine (26, 78) in which the test elements (42) are contained in a storage position (110, 114), said test elements (42) are moved, by means of a turning device (35, 36; 82), into a presentation position (72, 100, 116).