baber/WOPTO huggingface dataset:
Patent AU-2020256172-A1 (AU)
Title: System and method for detecting therapeutic agents to monitor adherence to a treatment regimen
Inventor: KARDOS KEITH
IPC: G01N33/50
Filed: 2020-03-31
Abstract: The disclosure provides methods, kits and systems for detecting a metabolite that is metabolized from a nucleotide reverse transcriptase inhibitor in a biological sample obtained from a subject, and uses thereof in monitoring adherence to pre-exposure prophylaxis and counseling subjects who are engaged in or prescribed pre-exposure prophylaxis. The present disclosure also provides methods of preventing HIV infection in patients at risk of contracting infection by monitoring adherence to a regimen and adjusting or modifying the dosing schedule of the regimen accordingly. The metabolite may be detected using proteomic methods, including but not limited to antibody based methods, such as a lateral flow immunoassay or lab based assays such as semi-quantitative LC-MS/MS.
Patent AU-2020260424-A1 (AU)
Title: Synthetic membrane-receiver complexes
Inventor: KAHVEJIAN AVAK
IPC: C12N15/07
Filed: 2020-10-28
Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating 
synthetic membrane-receiver complexes, and methods of treating or preventing diseases, 
disorders or conditions therewith.
Patent AU-2020291434-A1 (AU)
Title: Processed microbial extracellular vesicles
Inventor: BALLOK ALICIA
IPC: A61K35/74
Filed: 2020-06-11
Abstract: Provided herein are methods and pharmaceutical compositions related to processed microbial extracellular vesicles (pmEVs) that can be useful as therapeutic agents.
Patent AU-2020294779-A1 (AU)
Title: Systems and methods for fabricating a microchannel vascular network device and seeding a microchannel
Inventor: VACANTI JOSEPH P
IPC: C12M3/06
Filed: 2020-06-18
Abstract: A method of fabricating a microchannel device is provided. The method includes determining, based on a plurality of design criteria, a microchannel vascular network design. The microchannel vascular network design includes a first channel network, a second microchannel network based on the first channel network, and a structure for providing fluidic communication through between the first channel network and the second channel network. The method includes receiving, in electronic form, the microchannel vascular network design at a fabrication system. The fabrication system comprises a pre-polymer solution. The method includes forming, based on the microchannel vascular network design, a microchannel vascular network device of a polymer material at the fabrication system using the pre-polymer solution, thereby fabricating the microchannel vascular network device.
Patent AU-2020309829-A1 (AU)
Title: Naltrexone formulation
Inventor: PATEL ALKESHKUMAR NARAYANBHAI
IPC: A61P1/04
Filed: 2020-07-07
Abstract: The present invention related to lactose free, stable pharmaceutical composition comprising naltrexone or its pharmaceutically acceptable salt thereof. Further, the present invention provides process for the preparation of the said composition and its use for the treatment of Crohn's disease.
Patent AU-2020343810-A1 (AU)
Title: Anti-CXCR2 antibodies and uses thereof
Inventor: YANG GUANG
IPC: A61K39/395
Filed: 2020-09-03
Abstract: Provided are anti-CXCR2 antibodies and antigen-binding fragments thereof. The antibodies or fragments thereof specifically bind to N-terminal, extracellular domain of the CXCR2 protein. In various example, the antibodies or fragments thereof include a VH CDR1 of SEQ ID NO: 1, a VH CDR2 of SEQ ID NO: 2, a VH CDR3 of SEQ ID NO: 3, or any one of SQ ID NO: 7-14, a VL CDR1 of SEQ ID NO: 4, a VL CDR2 of SEQ ID NO: 5, and a VL CDR3 of SEQ ID NO: 6, or variants of each thereof. Methods of using the antibodies or fragments thereof for treating and diagnosing diseases such as cancer and inflammatory diseases are also provided.
Patent AU-2020354372-A1 (AU)
Title: Methods and compositions for DNA base editing
Inventor: XU JIANPING
IPC: C12N9/22
Filed: 2020-09-18
Abstract: The present invention relates to methods and compositions for modifying a target site in the genome of a cell. Fusion proteins including one or more DNA binding domains and one or more heterologous domains, such as DNA modifying domains, connected by improved linker sequences are provided. Codon optimized polynucleotides encoding fusion proteins including one or more DNA binding domains and one or more heterologous domains connected by improved linker sequences are provided.
Patent AU-2020357455-A1 (AU)
Title: Molecular guide system peptides and uses thereof
Inventor: BROWN KATHLYNN C
IPC: A61P35/00
Filed: 2020-07-31
Abstract: Disclosed are compositions comprising a nucleic acid sequence conjugated to one or more MGS peptides. Disclosed are methods of modifying gene expression of a gene of interest comprising administering to a cell a composition comprising a nucleic acid sequence conjugated to one or more MGS peptides, wherein the nucleic acid sequence binds to the RNA transcribed from the gene of interest, the gene of interest or a sequence upstream of the gene of interest. Disclosed are methods of targeting a gene of interest in an intracellular target comprising administering to a cell a composition comprising a nucleic acid sequence conjugated to one or more MGS peptides, wherein the MGS peptide targets the intracellular target, wherein the nucleic acid sequence binds to the RNA transcribed from the gene interest in an intracellular target.
Patent AU-2020402573-A1 (AU)
Title: Therapeutic device for cell therapy or cell stimulation
Inventor: ERDMANN RAIMUND
IPC: A61N1/06
Filed: 2020-12-11
Abstract: A therapeutic device for cell stimulation or cell therapy has a housing (12), which contains an electrode (1), a generator (3) for generating high-frequency pulses, a processor unit (6) comprising a control module, regulation module and computational module, a storage unit (9), a control element (5), and a controllable modulator (4) by means of which the generator (3) can be controlled. A sequence of voltage pulses including a plurality of voltage pulses can be generated by means of the modulator (4), the frequency of the sequence of voltage pulses being at least partly not constant.
Patent WO-2021142517-A1 (WO)
Inventor: RUSSO MARC
IPC: A61N1/06
Filed: 2021-01-18
Abstract: La présente invention concerne un système de stimulation de neurones, le système comprenant : un fil conducteur comprenant un corps de fil conducteur; au moins une électrode supportée par une portion distale du corps de fil conducteur, la au moins une électrode étant conçue pour être disposée près d'une corne dorsale dans la moelle épinière d'un sujet; et, au moins une paire de connexions s'étendant depuis les électrodes; un générateur de signal électriquement accouplé à la au moins une connexion et conçu pour générer des signaux électriques qui sont appliqués à la au moins une électrode, et les signaux électriques comprenant des formes d'onde pour stimuler les neurones à l'intérieur d'au moins l'une de la colonne dorsale et de la corne dorsale.
Patent WO-2021174316-A1 (WO)
Inventor: MOSS SCOTT
IPC: H02N2/18
Filed: 2021-03-05
Abstract: Some embodiments relate to an energy transduction device or apparatus. An example device or apparatus includes: a piezoelectric transducer; electrical conductors electrically coupled to the piezoelectric transducer; and an axially aligned magnet assembly arranged to apply static compressive force to the piezoelectric transducer, the magnet assembly being coupled to a base at one end and having a free opposite end. The magnet assembly is coaxial with the piezoelectric transducer and at least part of the magnet assembly is concentric with the piezoelectric transducer. The magnet assembly defines a gap between axially adjacent parts of the magnet assembly, wherein the gap is dimensioned to be sufficiently small that the magnet assembly applies a static compressive force to the piezoelectric transducer while being sufficiently large to allow for axial movement of the piezoelectric transducer without closing the gap.
Patent WO-2021248203-A1 (WO)
Inventor: MARTINO MIKAËL
IPC: A61K38/00
Filed: 2021-06-11
Abstract: The present invention provides a fusion protein comprising interleukin-1 receptor antagonist (IL-1Ra) and an extracellular matrix (ECM) binding peptide which specifically binds to one or more or all extracellular matrix proteins selected from the group consisting of fibrinogen, fibronectin, vitronectin, tenascin C and heparan sulfate and use of the fusion protein to treat conditions in which administration of IL-1Ra is beneficial or in which IL-1R1 signalling needs to be dampened, to enhance tissue regeneration, particularly bone regeneration and/or wound repair or for treating wounds, burns and muscle, cartilage, tendon and bone disorders, to enhance the regenerative activity of growth factor administration or to reduce inflammation or desensitisation of a cell to growth factor stimulation.
Patent AU-2021202107-A1 (AU)
Title: Harmonics filters using semi non-magnetic bobbins
Inventor: NEGRETE HERNANDEZ JOAQUIN ENRIQUE
IPC: H01F27/32
Filed: 2021-04-06
Abstract: WOU/4657 
Abstract of the Disclosure 
Disclosed are semi non-magnetic bobbins for use in core reactors, and core 
reactors that include the semi non-magnetic bobbins. The semi non-magnetic 
bobbins are made of a non-metallic material and provide core reactors that can 
withstand high temperatures and at the same time avoid eddy current effects. The 
disclosed semi non-metallically permeable bobbins also do not adversely affect 
electrical power quality and save power, and can be used to capture harmonics 
currents. When properly designed and arranged can be used to provide 
electromagnetic induction heaters using harmonics currents imported from an 
electrical power system as the working source of heat and provide a zero cost 
heating process.
Patent AU-2021202647-A1 (AU)
Title: Targeted Therapeutics
Inventor: CHIMMANAMADA DINESH U
IPC: C07K7/04
Filed: 2021-04-28
Abstract: The present invention provides pharmacological compounds including an 
effector moiety conjugated to a binding moiety that directs the effector moiety to a 
biological target of interest. Likewise, the present invention provides compositions, 
kits, and methods (e.g., therapeutic, diagnostic, and imaging) including the compounds.  
The compounds can be described as a protein interacting binding moiety-drug 
conjugate (SDC-TRAP) compounds, which include a protein interacting binding 
moiety and an effector moiety. For example, in certain embodiments directed to 
treating cancer, the SDC-TRAP can include an Hsp90 inhibitor conjugated to a 
cytotoxic agent as the effector moiety.
Patent AU-2021203203-A1 (AU)
Title: Solar Thermochemical Processing System and Method
Inventor: WEGENG ROBERT S
IPC: F22B1/00
Filed: 2021-05-19
Abstract: A solar thermochemical processing system is disclosed. The system includes a first unit 
operation for receiving concentrated solar energy. Heat from the solar energy is used to drive the 
first unit operation. The first unit operation also receives a first set of reactants and produces a 
first set of products. A second unit operation receives the first set of products from the first unit 
operation and produces a second set of products. A third unit operation receives heat from the 
second unit operation to produce a portion of the first set of reactants.
900 /go 
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Figure 9 
Sheet 9/14
Patent AU-2021203279-A1 (AU)
Title: Trusses for use in building construction and methods of installing same
Inventor: KENNELLY BERNARD JOSEPH
IPC: E04B1/38
Filed: 2021-05-21
Abstract: ll:\plw\Interwoven\NRPortbl\DCC\PLW\8781549 _.docx-21/05/2021 
ABSTRACT 
A truss assembly for use in building construction, comprising a first truss and one or more 
second trusses attached to the first truss to extend transversely to a face of the first truss upon 
erection of the truss assembly, wherein the or each second truss is hingedly connected to the 
first truss for swinging movement about a substantially vertical axis between a folded 
configuration in which the second truss lies adjacent the face of the first truss and an erected 
configuration in which the second truss extends transversely to said face.
Patent AU-2021203304-A1 (AU)
Title: Sprinkler with modular components and pop up deflector with lug(s) for rotational engagement
Inventor: CRAWFORD STEVEN E
IPC: B05B15/16
Filed: 2021-05-21
Abstract: OF THE DISCLOSURE 
A sprinkler includes a pop-up deflector plate that is engageable with a brake assembly in 
an extended position. A brake module is secured to a sprinkler body and includes a rotatable 
connector coupled with the brake assembly. The pop-up deflector plate is disposed adjacent the 
nozzle and engages the rotatable connector in the extended position.
Patent AU-2021218219-A1 (AU)
Title: Drilling head for a percussive displacement ground drilling device and use of a drilling head for a percussive displacement ground drilling device
Inventor: Püttmann Franz-Josef
IPC: E21B4/06
Filed: 2021-08-20
Abstract: The invention relates to a drilling head for a percussive displacement ground drilling 
device with a first and a second drilling head section, the first drilling head section 
having discharge ducts and the second drilling head section having a cross section that 
increases in the longitudinal direction, the second drilling head section having several 
step-shaped areas.
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Patent AU-2021222383-A1 (AU)
Title: A security sheet
Inventor: SUGDON MATTHEW
IPC: B42D25/378
Filed: 2021-02-04
Abstract: The present disclosure is directed towards a security sheet (10) for displaying personal data (11) comprising a plastic substrate (12) comprising first and second outer surfaces (13, 14). A first opaque region (21) extends partially across the plastic substrate (12) between the first and second outer surfaces (13, 14). A first window (50) is at least partially surrounded by the first opaque region (21). A security device (51) comprises a transparent first device region (52) and a second device region (53) formed from a second device insert (55). The first and second device regions (52, 53) have different optical detection characteristics. The security device (51) is arranged in the plastic substrate (12) such that, when viewed in reflected light incident upon the first outer surface (13), at least part of the first device region (52) is visible at least partially around the second device region (53) in the first window (50).
Patent AU-2021226026-A1 (AU)
Title: Targeted expression of microbial cholesterol catalysis genes reduces excess lipid
Inventor: TOPORS MOURAD
IPC: C12N9/04
Filed: 2021-02-26
Abstract: Disclosed herein are compositions, constructs, cassettes, vectors, cells, nucleic acids, peptides, proteins, protocols and methods for reducing cholesterol and lipid buildup in mammalian subjects, via gene and/or cell therapeutic treatments. In many embodiments, the disclosed compositions, cells, constructs, cassettes, vectors, nucleic acids, peptides, proteins, protocols and methods may help to reduce lipid levels in mammals. In one embodiment, the disclosed compositions, cells, constructs, cassettes, vectors, nucleic acids, peptides, proteins, protocols and methods are useful in reducing lipid build-up, especially cholesterol, in liver cells.
Patent AU-2021231203-A1 (AU)
Title: A grid framework structure for a storage system
Inventor: BATES MARTYN
IPC: B65G1/04
Filed: 2021-03-02
Abstract: A grid framework structure for supporting a load handling device operative to move one or more containers comprises a plurality of upright columns arranged to form a plurality of vertical storage locations for one or more containers to be stacked between the upright columns and be guided by the upright columns in a vertical direction, wherein the plurality of upright columns are interconnected at their top ends by a first set of grid members (118) extending in a first direction and a second set of grid members (120) extending in a second direction, the second set of grid members (120) running transversely to the first set of grid members (118) in a substantially horizontal plane to form a grid structure (50) comprising a plurality of grid cells (54). The first and the second set of grid members (118, 120) are sub-divided into a plurality of grid elements (119a-c, 121a-c) such that adjacent grid elements (119a-c, 121a-c) extending in the first direction or the second direction are offset with respect to each other in the horizontal plane by at least one grid cell.
Patent AU-2021232206-A1 (AU)
Title: Ocular implant and method of making same
Inventor: WHITE ANDREW
IPC: A61F9/007
Filed: 2021-03-02
Abstract: An ocular implant (10) for conveying intraocular fluid away from a site of excess intraocular fluid within a patient, the implant (10) including: a body (12) including one or more drainage channels (20) each having an outlet (24) fluidly communicable with a drainage site located away from the site of excess intraocular fluid; and an elongated tubular member (30) fluidly communicable with the body (12), the member (30) having a first end portion (32) providing an inlet (38), a second end portion (34) providing an end (40), and a lumen extending between the inlet (38) and the end (40), wherein the inlet (38) is fluidly communicable with the site of excess intraocular fluid so that the intraocular fluid is able to flow past the inlet (38) and through the lumen towards the end (40), and wherein the second end portion (34) includes one or more openings (42) each fluidly communicable with a respective one of the one or more drainage channels (20) to permit the intraocular fluid to flow from the second end portion (34) to each of the outlets (24).
Patent AU-2021232704-A1 (AU)
Title: Debriding dressing for use with negative pressure and fluid instillation
Inventor: LOCKE CHRISTOPHER BRIAN
IPC: A61M1/00
Filed: 2021-09-14
Abstract: Systems, methods, and apparatuses for debriding a tissue site are described. The system 
includes a manifold and a cover adapted to form a sealed space over the tissue site for 
providing negative pressure. The system also includes a debridement tool positioned between 
the manifold and the tissue site. The debridement tool having a tissue-facing surface and a 
plurality of holes separated from each other by walls. The walls have transverse surfaces 
extending between the tissue-facing surface and an opposite surface that form cutting edges.  
The holes have a perforation shape factor that allows the holes to collapse from a relaxed 
position to a contracted position in response to the application and removal of negative 
pressure from the sealed space. The cutting edges debride the tissue site in response to 
movement between the relaxed position and the contracted position.  
FIG. 1
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Patent AU-2021245122-A1 (AU)
Title: Smoke alarm
Inventor: ZAMPARELLI DANIEL
IPC: G08B29/18
Filed: 2021-10-06
Abstract: SMOKE ALARM 
Abstract 
Disclosed herein is a smoke detector that includes: mains power connectivity adapted 
to couple to a mains power supply; a long-life battery located in a sealed compartment; a 
microcontroller; a smoke detector coupled to said microcontroller so as to generate a trigger 
when said smoke detector detects smoke; a power source selector for selecting between 
mains power supply and said long-life battery to power said microcontroller, based on the 
presence of said mains power supply; and a buzzer for issuing an audible alert when said 
microcontroller is triggered by said smoke detector detecting the presence of smoke.
Patent AU-2021250537-A1 (AU)
Title: Method for the control of volume expansion of hydraulically setting compositions comprising steel making slag
Inventor: SOUDIER JEROME
IPC: C04B28/08
Filed: 2021-03-18
Abstract: The present invention belongs to the field of hydraulically setting compositions comprising steel making slag. Specifically, the present invention provides a method for controlling the volume expansion of a hydraulically setting composition comprising steel making slag, said method including a step of adding a silica source to said composition. Furthermore, the present invention also provides hydraulically setting compositions obtained by such methods and their uses.
Patent AU-2021269916-A1 (AU)
Title: Write sort management in data storage system
Inventor: HATFIELD BRIAN
IPC: G06F11/14
Filed: 2021-05-05
Abstract: In one method of write sort management, a write sort task related to write sorting a write list of data units to be destaged to storage, is assigned to a storage controller to improve the load balance among plural storage controllers. The available processing capacities of each of the storage controllers is determined by, for example, polling each of the storage controllers. A write sort task may then be assigned to a selected storage controller as a function of determined available processing capacities of each of the storage controllers to improve the load balance among the storage controllers.
Patent AU-2021273527-A1 (AU)
Title: Thermally insulated housing for a heat-producing, heat-radiating device
Inventor: FINNERTY CAINE
IPC: H01M8/04701
Filed: 2021-11-22
Abstract: A thermally insulated housing for enclosing a heat producing, heat radiating device, comprising: a first 
housing possessing conjoined side, top and bottompanels such panels havingopposed internaland exposed 
externalsides, the panelsbeing dimensioned and configured to completely enclose a heat-producing, heat
radiating device, the interior sides of the first housing panels having adherently attachedthereto at least one 
refractory thermal insulation assembly or combination of such assemblies, each such thermal insulation 
assembly or combination of thermal insulation assemblies defining at least one structure made up of 
superimposed layers of pre-dimensioned and pre-configured refractory thermal insulation sections with a 
major side of a thermalinsulation assembly or combination of such assemblies facing toward the heat
producing, heat-ra diating device, the dimensions, configuration and maximum service temperature of each 
thermalinsulation assembly or combination of such assemblies being such as to substantially completely 
and continuously linethe internalsurfaces of allpanels of the first housing thereby inhibiting thermallosses 
from the enclosed heat-producing,heat-radiating device to a predetermined extent, each thermalinsulation 
assembly, excludinga directpath forthe flowof IRradiation from the heat-producing,heat-radiating device 
while maintaining a maximum predetermined surface temperature on the external surface of each first 
housing panel.
Patent AU-2021302892-A1 (AU)
Title: Hypervisor protected key
Inventor: BUENDGEN REINHARD
IPC: G06F21/62
Filed: 2021-06-24
Abstract: A method, a computer system, and a computer program product may provide a cryptographic key object to a guest virtual server for use in cryptographic operations. The guest virtual server may register with a hypervisor. The hypervisor may generate a guest wrapping key associated with guest credentials from the registering. The hypervisor may also generate a satellite virtual server instance. The guest virtual server and the satellite virtual server instance share a master key that cannot be accessed by the hypervisor or by any guest virtual server. The trusted hypervisor may pass a copy of the guest wrapping key to the satellite virtual server instance. A random guest key may be generated and may be wrapped with a guest wrapping key thereby producing a wrapped guest key. The hypervisor may convert the wrapped guest key to be a protected key that serves as the cryptographic key object.
Patent AU-2021344103-A1 (AU)
Title: Transmission method and apparatus for mimo system
Inventor: KIM JONGHWAN
IPC: H04B7/06
Filed: 2021-03-10
Abstract: A communication technique for convergence between an IoT technology and a 5