baber/WOPTO huggingface dataset:
Patent CA-2492861-A1 (CA)
Inventor: FAN JUNYING
IPC: A61P29/00
Filed: 2003-07-21
Abstract: La présente invention concerne un procédé de préparation de certains composés de pyrrolotriazine correspondant à la formule (I), ainsi que des sels pharmaceutiquement acceptables de ces composés. Les composés de formule (I) inhibent l'activité de tyrosine kinase de récepteurs de facteurs de croissance tels que VEGFR-2 et FGFR-1, ce qui les rend utiles en tant qu'agents anticancéreux. Ces composés de formule (I) sont également utiles pour le traitement d'autres maladies associées aux voies de transduction de signal fonctionnant par l'intermédiaire des récepteurs de facteur de croissance.
Patent CA-2494326-A1 (CA)
Title: Antigels aqueux sans glycol contenant des sels d'acides dicarboxyliques
Inventor: FERNANDEZ-GONZALEZ MONICA
IPC: C23F11/14
Filed: 2003-08-01
Abstract: La présente invention concerne un antigel aqueux contenant 10 à 50 % en poids d'un ou de plusieurs acides dicarboxyliques, de préférence d'acides dicarboxyliques aliphatiques présentant 4 à 12 atomes de carbone sous forme de sel de métaux alcalins, d'ammonium ou de métaux alcalino-terreux. Ces sels sont de préférence utilisés en combinaison avec au moins une autre substance. On obtient ainsi des antigels assurant une bonne protection contre le gel, une haute protection contre la corrosion et présentant une bonne conductivité thermique.
Patent CA-2495789-A1 (CA)
Title: Fine-grained rare earth activated zinc sulfide phosphors for electroluminescent displays
Inventor: STILES JIM
IPC: H05B33/04
Filed: 2003-08-25
Abstract: An improved fine grained zinc sulfide phosphor is provided for use in ac electroluminescent displays. The fine-grained zinc sulfide phosphor film exhibits improved luminance and may be used in conjunction with a structure or substance to minimize or prevent reaction of the fine grained phosphor with oxygen. The invention is particularly applicable to zinc sulfide phosphors used in electroluminescent displays that employ thick dielectric layers subject to high processing temperatures to form and activate the phosphor films.
Patent CA-2497072-A1 (CA)
Inventor: HUTCHISON DAVID A
IPC: C10L1/224
Filed: 2005-02-16
Abstract: A multi-functional composition for use as an additive for fuels and lubricants. The composition includes an amination product of a hydrocarbyl substituted succinic acylating agent and a mixture containing an aliphatic polyamine and an aromatic polyamine. The molar ratio of aliphatic polyamine to aromatic polyamine in the mixture ranges from about 10:0.1 to about 0.1:10. The amination product contains at least about 0.1 molar equivalent of the polyamine mixture to 1 molar equivalent of the hydrocarbyl substituted succinic acylating agent.
Patent CA-2500865-A1 (CA)
Title: Procede de conception d'une poudre d'interference lumineuse dont les particules sont enrobees d'un film multicouche, methode de fabrication associee, et poudre d'interference lumineuse dont les particules sont enrobees d'un film multicouche
Inventor: ATARASHI TAKAFUMI
IPC: C09C1/00
Filed: 2002-10-01
Abstract: L'invention concerne une poudre d'interférence lumineuse dont les particules sont enrobées d'un film multicouche, laquelle poudre résistant aux intempéries, et une nouvelle couleur voulue, ainsi que le procédé de conception de fabrication de cette poudre. Des particules basiques présentant une fonction voulue sont sélectionnées et une couleur voulue est sélectionnée. La courbe spectrométrique de la couleur voulue et la valeur du système de couleurs du tableau CIELAB sont mesurées, et une matière d'enrobage utilisable ainsi que son indice de réfraction sont inclus en tant que facteurs pour résoudre une formule de récurrence d'interférence de film en couches minces, ce qui permet d'obtenir la matière de chaque film, l'épaisseur du film, et l'ordre de fabrication des films de la poudre d'interférence lumineuse dont les particules sont enrobées d'un film multicouche, laquelle poudre présentant le système de couleur de tableau CIELAB, dans lequel la différence de couleur est minimale et tonalité chromatique est proche de 1.
Patent CA-2501103-A1 (CA)
Inventor: EISENMANN SIEGFRIED A
IPC: F01C1/02
Filed: 2005-03-17
Abstract: The invention relates to a displacement pump with variable volume flow. The pump comprises a casing with a chamber formed therein which includes an inlet opening on a low pressure side and an outlet opening on a high pressure side for a fluid. The pump further comprises an internal rotor which is accommodated in the chamber and has a central ring axis which surrounds the internal rotor. In the case of rotary driving, at least one of the internal rotor and the ring forms, together with the internal rotor, at least one delivery cell in which the fluid is delivered from the low pressure side to the high pressure side. An adjusting device is arranged such that during an adjusting movement, it rolls off on the casing without slipping. In accordance with the invention, the internal rotor is fixed to the adjusting device such that it can be rotated about the rotational axis. As well, the position of the rotational axis relative to the ring axis of the ring is adjusted by the adjusting movement of the adjusting device.
Patent CA-2501241-A1 (CA)
Title: Microwave applicator
Inventor: CRONIN NIGEL
IPC: A61B18/18
Filed: 2003-09-15
Abstract: A microwave applicator comprising a coaxial electrical input (4) and a waveguide (1) filled with dielectric (2), an inner conductor (7) of the coaxial input extending longitudinally within one end of the waveguide to launch microwaves in the TM01 mode to travel to the distal end face (8) of t he waveguide so that microwaves are transmitted when the distal end face is contacted by the biological tissue to be treated.
Patent CA-2501795-A1 (CA)
Title: Seal positioning assembly
Inventor: MCFARLANE RICHARD H
IPC: A61M5/178
Filed: 2004-08-09
Abstract: An assembly structured to selectively orient a seal between an open position and a closed position. The assembly includes an expander structure disposable into a seal open or a seal close orientation by being rotated or otherwise movable into and out of forced engagement with predetermined portions of the seal structure. The seal open orientation disposes the seal structure out of engagement with an instrument passing there through and may also facilitate a rapid venting of insufflation gas from an inflated body cavity, such as when the seal positioning assembly is used with a trocar assembly involved in the performance of laprascopic or like surgery. A biasing assembly may be connected to the seal structure to bias it in a normally closed position in the absence of an instrument disposed within the seal structure.
Patent CA-2502804-A1 (CA)
Inventor: WALLACE MARK
IPC: H04J99/00
Filed: 2003-10-24
Abstract: La présente invention concerne une estimation de canal et un traitement spatial pour système TDD MIMO. L'invention permet d'effectuer un étalonnage afin de compenser les différences dans les réponses des chaînes de transmission et de réception au point d'accès et au terminal utilisateur. Au cours d'un fonctionnement normal, un pilote MIMO est transmis sur une première liaison et utilisé pour dériver une estimation de la réponse de canal de la première liaison, que l'on décompose afin d'obtenir une matrice diagonale de valeurs singulières et une première matrice unitaire contenant les vecteurs propres gauches de la première liaison et les vecteurs propres droits d'une seconde liaison. On transmet une référence commandée sur la seconde liaison à l'aide des vecteurs propres de la première matrice unitaire, que l'on traite afin d'obtenir la matrice diagonale et une seconde matrice unitaire contenant à la fois les vecteurs propres gauches de la seconde liaison et les vecteurs propres droits de la première liaison. On peut utiliser chaque matrice unitaire pour effectuer un traitement spatial de la transmission et de la réception des données via les deux liaisons.
Patent CA-2506279-A1 (CA)
Inventor: REYES JOSE D
IPC: C08K5/51
Filed: 2003-11-13
Abstract: Flame retardant plastic resin blends comprise an intumescent flame retardant and at least one plastic resin. Engineering resin blends comprise an intumescent flame retardant and at least one engineering resin. Thermoset resin blends comprise an intumescent flame retardant and at least one thermoset resin. The plastic resin blends and the engineering resin blends a re non-halogen. The thermoset resin blends are substantially non-halogen.</SDOA B>
Patent CA-2506749-A1 (CA)
Title: Method of drug loading in liposomes by gradient
Inventor: JENSEN GERARD M
IPC: A61K31/704
Filed: 2003-11-26
Abstract: A method for encapsulation of pharmaceutical agents (e.g., antineoplastic agents) in liposomes is provided, having preferably a high drug:lipid ratio.  Liposomes can be made by a process that loads the drug by an active mechanism using a transmembrane pH gradient. Using this technique, trapping efficiencies approach 100%. Drug:lipid ratios employed are higher than for older traditional liposome preparations, and the release rate of the drug from the liposomes is reduced. After loading, residual acid is quenched with a quenching agent that is base permeable at low temperatures. The residual aciditiy is thus reduced and chemical stability (e.g. against hydrolysis) is enhanced. The stability of both the liposome and the pharmaceutical agent is thus maintained, prior to administration. The pH gradient is, however, present when the liposome is administered in vivo because the quenching agent rapidly exits the liposome.
Patent CA-2508636-A1 (CA)
Title: Use of l-carnitine for the treatment of cardiovascular diseases
Inventor: KOVERECH ALEARDO
IPC: A61P9/10
Filed: 2004-03-03
Abstract: The use of L-carnitine or one of its pharmaceutically acceptable salts is described for the preparation of a medicine useful for reducing the number of deaths caused by acute myocardial infarction and for improving the short-and-long-term prognosis in the patients treated with it, in which L-carnitine is administered parenterally within the first few hours of onset of the symptoms of acute myocardial infarction at an initial dose of 9 grams a day for 5 days, after which the treatment is continued at a dose of 4 grams a day by the enteral route.
Patent CA-2509610-A1 (CA)
Inventor: STOECKEL DIETER
IPC: A61B17/064
Filed: 2005-06-09
Abstract: A medical fastener having first undeployed shape for loading into an applier, and a second deployed shape for connecting tissue together. The fastener includes a crown having two ends and first and second legs one attached to each end of the crown. The legs are separated from one another when the fastener is in the first shape.  The legs comprise first, second and third layers of material joined together. The first layer of material is a superelastic alloy having a relaxed configuration substantially in the second shape of the fastener. The second layer of material comprising a linear elastic material having a relaxed configuration substantially in the first shape of the fastener. The second layer of material has sufficient rigidity to keep the first layer in the first shape prior to the fastener being deployed. The third layer of material is disposed between the first and second layers and is a material which substantially prevents diffusion between the first and second layers of material.
Patent CA-2510646-A1 (CA)
Inventor: GLADKOV ALEXANDER A
IPC: H02P7/00
Filed: 2004-01-29
Abstract: A multiphase motor has a plurality of ferromagnetically isolated stator electromagnets distributed about an axis of rotation. Successive ranges of speed during which the motor can be expected to operate are defined. A  specific subset of the electromagnets is associated for each speed range, each specific subset comprising a different combination of electromagnets.  Respective voltage magnitudes to be applied to each phase winding for each defined speed range are predefined. The motor speed is sensed throughout motor operation. In each defined speed range, only the electromagnets of the associated subset are energized, each of the energized electromagnets having applied thereto a different predefined voltage magnitude.
Patent CA-2512802-A1 (CA)
Inventor: ZHANG WENWU
IPC: B23K26/12
Filed: 2005-07-21
Abstract: A laser forming apparatus (10) includes a motion system (14). A mounting fixture (22) is affixed to the motion system for supporting a workpiece (12). A plenum (24) is affixed to the fixture for surrounding the workpiece. A gas supply (36) is joined in flow communication with the plenum for channeling thereto an inert gas under pressure to fill the plenum. A laser (26) is aligned with the plenum (24) for projecting a laser beam (28) at the workpiece (12) inside the portable plenum (24).
Patent CA-2513691-A1 (CA)
Inventor: BALLARD LARRY
IPC: C25D5/34
Filed: 2004-01-14
Abstract: The invention relates to a method that involves (a) removing graphite from at least one surface of a metal graphite composite material; (b) chemically cleaning or plasma etching the surface of the metal graphite composite material; (c) applying a metal-containing material to the surface of the chemically cleaned or plasma etched metal graphite composite material, and thereby forming an intermediate layer; (d) applying a metal coating on the intermediate layer, and thereby forming a composite material. The invention also relates to a composite material comprising (a) a metal graphite composite substrate having at least one surface that is substantially free of graphite;  (b) a metal-containing intermediate layer located on a surface of the substrate; and (c) a metal coating on the intermediate layer.
Patent CA-2514856-A1 (CA)
Inventor: STOESZ DONALD
IPC: B60G11/10
Filed: 2005-07-29
Abstract: In an alternative assembly of multiple leaves in an assembled leaf spring; a forged fastener is used instead of a bolt and nut. To form the forged fastener, a cylindrical member with a preformed head on one end is inserted through the centre holes of each leaf of the leaf spring and the inserted end is forged in a press to match the head of the fastener on the other side. This is used to make a permanent connection, to make both sides of the fastener identical for use with an under-slung or over-slung axle arrangement, and to reduce process time by eliminating the need to cut and peen the conventional bolt.
Patent CA-2517931-A1 (CA)
Inventor: KEMP FRANK
IPC: G01B3/20
Filed: 2005-08-26
Abstract: A machined block used in conjunction with a standard vernier and or caliper so that comparative readings can be read for wear on wheel flanges.
Patent CA-2520951-A1 (CA)
Inventor: LEHMANN DIRK
IPC: B63H25/52
Filed: 2005-09-23
Abstract: The rudder post (40) for rudders for water vehicles has end sections (41, 42) made of a metallic material, in particular of wrought iron, and a mid post section (45) made of a nonmetallic material connected with the end sections so that the rudder post has a relatively low weight even for a very big length by maintaining a high flexural strength and torsion stiffness.
Patent CA-2521914-A1 (CA)
Inventor: AMINO HIDEO
IPC: B60K11/04
Filed: 2005-09-30
Abstract: An object of the invention is to improve the motorcycle radiator arranging construction with a view to improving the external appearance characteristic of a motorcycle. In a motorcycle having a water-cooled engine 12 installed thereon, a radiator 75 is arranged erect in a space 87 defined between the engine 12 and a rear wheel 16 in such a manner that a front surface 75a thereof is directed in a longitudinal direction of the vehicle and is supported on a body frame 11, whereby the radiator 75 is made difficult to see from the outside compared with a case where the radiator is arranged at the front of the body frame to thereby make conspicuous, for example, the design of the engine.
Patent CA-2523842-A1 (CA)
Title: Massaging device
Inventor: RINT MOSHE
IPC: A47C31/00
Filed: 2004-04-29
Abstract: The present invention presents a thorny mosaic-like, fluid pressurized, massaging article characterized by a planar mosaic matrix; said matrix comprising at least one multiple typical arrangement, whereat a massaging thistle is surrounded by a plurality of either a fluid or gas conduits, in the manner while the fluid pressure is decreased in at least one conduit, the pressure in at least one other adjacent conduit is increased so the central massaging thistle is forced to incline either towards said pressurized or depressurized conduit and vice versa. The present invention also presents a massager useful for massaging the body comprising a flexible flat liquid container; wherein said liquid are adapted to flow repetitively inside said container in a predetermined course; and a plurality of massaging member comprising a proximal finger-like end and a distal flag-like end, wherein said proximal end is located outside said container and further wherein said distal end is located inside said container so a direct liquid-communication is provided between said flag-like end and at least a portion of the liquid of said container.
Patent CA-2524303-A1 (CA)
Title: Method and system for providing sim-based roaming over existing wlan public access infrastructure
Inventor: CHINNASWAMY SUDHAGAR
IPC: G06F21/35
Filed: 2004-04-29
Abstract: A method and apparatus for performing SIM-based authentication and authorization in a WLAN Internet Service Provider (WISP) network supporting the universal access method (UAM) of authentication and authorization enabling roaming for customers of mobile service providers onto said networks. In addition, the invention provides a secure way of authenticating the customer's client device to the mobile service provider's network by employing temporary credentials for authentication that provide privacy of the user's identity and prevent replay attacks. Finally, if the WISP network supports the 'pass-through' facility, the authentication can be done more securely and quickly.
Patent CA-2527689-A1 (CA)
Title: Recombinant anti-cd30 antibodies and uses thereof
Inventor: DORONINA SVETLANA
IPC: A61K45/06
Filed: 2004-05-28
Abstract: The present invention relates to methods and compositions for the treatment of Hodgkin's Disease, comprising administering proteins characterized by their ability to bind to CD30, or compete with monoclonal antibodies AC10 or HeFi-1 for binding to CD30, and exert a cytostatic or cytotoxic effect on Hodgkin's disease cells in the absence of effector cells or complement. Such proteins include derivatives of monoclonal antibodies AC10 and HeFi-1. The proteins of the invention can be human, humanized, or chimeric antibodies; further, they can be conjugated to cytotoxic agents such as chemotherapeutic drugs. The invention further relates to nucleic acids encoding the proteins of the invention. The invention yet further relates to a method for identifying an anti-CD30 antibody useful for the treatment or prevention of Hodgkin's Disease.
Patent CA-2528075-A1 (CA)
Title: Low temperature liquid polythioether polymers
Inventor: LEON DAVID ROSENDO
IPC: C08G75/04
Filed: 2004-06-04
Abstract: Polythioether polymers, curable compositions of polythioether polymers, the process of making polythioether polymers, and the use of polythioether polymers in sealants, wherein the polythioether polymers and curable compositions are liquid at a temperature of 20~C or less, are disclosed.
Patent CA-2529754-A1 (CA)
Inventor: NIKOLAYCHIK VICTOR
IPC: A61F2/06
Filed: 2004-06-18
Abstract: Devices and methods for reducing, eliminating,preventing, suppressing, or treating tissue responses to hemostatic devices e.g., biological sealants or vascular procedures are disclosed. The invention employs a combination of resorbable, biocompatible matrix materials and a variety of therapeutic agents, such as antiproliferatives or antibiotics, applied to a vascular puncture or incision to achieve hemostasis following diagnostic or interventional vascular catheterizations and to treat neointimal hyperplasia and stenosis . A matrix of a material such as collagen provides a reservoir of a therapeutic agent such as rapamycin (sirolimus) and its derivatives and analogs for delivery at a tissue site at risk for vasculoproliferation, infection, inflammation, fibrosis or other tissue responses.
Patent CA-2531288-A1 (CA)
Inventor: VAN GEMEN BOB
IPC: C12Q1/68
Filed: 2004-07-01
Abstract: Statins are widely used for the treatment of high cholesterol levels. In the present invention the effect of statins on mitochondrial nucleic acid and the activation state of mitochondria is used in methods for determining whether a subject is at risk of developing side effects of statin treatment, methods for the treatment of a clinical symptom associated with reduced mitochondrial function. Further provided are kits and the like comprising a means for the detection of mitochondrial nucleic acid, or the activation of a mitochondrion for use in a method mentioned above.
Patent CA-2532815-A1 (CA)
Title: Thermal ablation of biological tissue
Inventor: DANIEL STEVEN A
IPC: A61B18/14
Filed: 2004-07-12
Abstract: An ablation device is described comprising an introducer and an electrode array. The electrode array couples to a distal end of the introducer. The electrode array includes a center member having a distal end configured to penetrate tissue and a plurality of electrodes. Proximal and distal ends of each electrode are relatively fixed. The electrodes are dynamically configurable from a retracted state to a deployed state in which the electrodes form a relatively spherical shape in a tissue volume.
Patent CA-2534894-A1 (CA)
Title: Fungus resistant plants and their uses
Inventor: ALLEFS JOSEPHUS JACOUBS HENRIC
IPC: C07K14/415
Filed: 2004-08-03
Abstract: The present invention relates to a novel method for increasing the resistance, of a plant, in particular of a Solanaceae, preferably of potato and tomato, to plant pathogens of the phylum Oomyceta comprising increasing the activity of the polypeptid of the present invention. The invention further relates to polynucleotides and vectors comprising these polynucleotides. The invention furthermore relates to corresponding vectors, cells, transgenic plants and transgenic propagation material derived from them, methods to produce them and to their use for the production of foodstuffs, feeding stuffs, seed, pharmaceuticals or fine chemicals.
Patent CA-2535289-A1 (CA)
Title: Wall mounted elevating mechanism
Inventor: HALLMAN GEORGE
IPC: A61B16/00
Filed: 2006-02-06
Abstract: A wall mounted elevating mechanism that includes a frame and a sliding member arranged therein. The elevating mechanism also includes a support arm extending from the sliding member with a table secured to the support arm. A lifting mechanism is arranged between the frame and the sliding member. A switch is electronically connected to the lifting mechanism.
Patent CA-2536921-A1 (CA)
Inventor: SIMON ULRICH
IPC: B29C67/04
Filed: 2006-02-17
Abstract: Disclosed is use of a polymer powder of block polyetheramide, produced by the polycondensation of oligoamide dicarboxylic acid and polyetheramine for preparing a three-dimensional molding by a layer-by-layer process where regions of the polymer powder layer are selectively melted via the introduction of electromagnetic energy, and after cooling, the regions are then solidified and can be removed in the form of a molding from the powder bed.