baber/WOPTO huggingface dataset:
Patent NZ-199319-A (NZ)
Title: Carbaprostacyclin derivatives and pharmaceutical compositions
Inventor: SKUBALLA W
IPC: C07C59/62
Filed: 1981-12-18
Abstract: Carbacyclin derivatives of Formula I    <IMAGE>  (I)  wherein R1 is OR2, wherein R2 is hydrogen, alkyl, cycloalkyl, aryl, a heterocyclic residue, or NHR3, wherein R3 is an acid residue or hydrogen; X is oxygen; A is -CH2-CH2-, trans-CH=CH-, or -C 3BOND C-; W is free or functionally modified hydroxymethylene or free or functionally modified   <IMAGE>  wherein the OH-group can be in the  alpha - or beta -position; D is a straight-chain or branched, saturated or unsaturated aliphatic group of 1-10 carbon atoms, which can optionally be substituted by fluorine atoms, 1,2-methylene, 1,1-trimethylene; E is -C 3BOND C- or -CR6=CH7- wherein R6 and R7 are hydrogen or alkyl of 1-5 carbon atoms; R4 is an aliphatic group, cycloalkyl, optionally substituted aryl, or a heterocyclic group; R5 is free or functionally modified hydroxy and, when R2 is hydrogen, the physiologically compatible salts thereof with bases, have valuable pharmacological properties.
Patent NZ-220465-A (NZ)
Title: Adhesive system for securing catheters or cannulas to the skin
Inventor: BECHER FRANK
IPC: A61F13/02
Filed: 1987-05-27
Abstract: Fixing system for securing catheters, cannulas or similar with a skin foil (3) coated with a skin-adhesive layer (2), with a covering foil (1), and a top plaster (6) with an adhesive layer (5) which adheres to the skin foil (3), with a top-plaster covering layer (4), as well as a process for the sterile securing of a cannula to the skin, involving the following steps: application of a bacteria-tight skin foil with a skin adhesion layer to the skin in the region of cannula penetration; passing of the cannula through the skin foil; application of an adhesive, which forms an elastic, bacteria-tight film which adheres to the lower plaster, to the region of the latter surrounding the point of penetration and to the cannula section which projects from the skin; and sticking the top plaster over the cannula.
Patent NZ-234896-A (NZ)
Title: Substituted xanthines and pharmaceutical compositions
Inventor: TOSHIZO TANAKA
IPC: A61P1/00
Filed: 1990-08-14
Abstract: Therapeutic agents for the treatment of peptic ulcer disease, containing as active ingredient, at least one compound of the general formula I <CHEM>  wherein one of R<1> and R<3> is <CHEM> (wherein m is 1-5 R<4> represents a (C1-C4)alkyl group); the other one of R<1> and R<3> is hydrogen, (C3-C6)alkenyl or (C1-C8)alkyl which can be substituted with up to 2 hydroxyl groups or a (C1-C4)alkoxy group; and R<2> is (C1-C4)alkyl.
Patent NZ-244200-A (NZ)
Title: Antibiotic compounds ll-e19020 epsilon and ll-e19020 epsilon 1 and their
Inventor: CARTER GUY THOMAS
IPC: C12P17/16
Filed: 1992-09-03
Abstract: The invention provides antibiotics designated LL-E19020 Epsilon and LL-E19020 Epsilon1 which are derived from the microorganism Streptomyces lydicus ssp. tanzanius NRRL 18036.
Patent NZ-264765-A (NZ)
Title: Radial tyre with beads to closely fit rim seats
Inventor: BEARD RICHARD CHARLES
IPC: B60C15/024
Filed: 1994-10-25
Abstract: An improved radial ply pneumatic tire 30 is described. The improved tire 30 has a first annular surface 23 located between the heel 22B and toe 22A of each bead 33 and a second surface 24 extending radially outwardly from the bead heel 22B. The first surface 23 is designed to be in contact with the bead seat 42 of the design rim 40 when the tire 30 is mounted and inflated to normal pressure. The first annular surface 23, when the tire 30 is unmounted, forms an average angle  beta  with the axis of the tire, when the beads 33 are axially spaced a distance D equal to the design rim width as defined herein. The average angle  beta  is in the range of at least one-half degree and less than three degrees greater than the angle formed between the mating bead seat 42 of the design rim 40 and the axis of the tire. The second surface 24 is designed to be in contact with an annular flange 44 portion of the design rim 40 when the tire is mounted and inflated to normal pressure. The second surface 24 is perpendicular to the axis of rotation. Preferably the angle  beta  is in the range of 1 DEG  to 2 DEG greater than the rim seat angle, more preferably the angle  beta  is 1.5 DEG  greater. The angular relationships relative to the design rim flange 44 permit the bead 33 to exhibit uniform compression upon mounting to the design rim 40, thereby improving the stiffness and handling characteristics of the tire 30. <IMAGE>
Patent NZ-272107-A (NZ)
Title: Thixotropic adhesive gel comprising a self-crosslinking polyvinylacetate and a cellulose fibre filler; package and preparation
Inventor: COLUMBUS PETER SPRIOS
IPC: C08L1/00
Filed: 1995-05-11
Abstract: A thixotropic adhesive gel comprises a self-crosslinking copolymer of polyvinyl acetate and N-methylol acrylamide and a cellulose fibre filler. Also claimed are (i) a process of preparing such a gel comprising mixing (wt.%): (A) a water-soluble, high viscosity thickening agent (0.10-75); (B) a defoamer (0.05-0.40); (C) a vinyl acetate/N-methylolacrylamide copolymer, dispersed in water (25.00-45.00 solids); (D) a plasticiser/coalescing agent (1.00-3.00); (E) an acidic catalyst (0.50-1.00); (F) fine particle-size cellulosic fibres (4.00-12.00); and (G) a preservative (0.10); and (ii) an adhesive gel compsn. comprising a crosslinkable polyvinylacetate copolymer, cellulosic fibre filler and thickening agent, the gel having a thixotropic index of 1.5-7. Pref. the copolymer is crosslinked through the action of an acidic metal crosslinking catalyst; the compsn. further comprises a water-soluble high viscosity thickener, a plasticiser/coalescing agent, a defoamer, and a preservative. The gel produced pref. has viscosity no greater than 90000 cP one month after prepn.; and the cellulose fibres are pref. wood fibres of particle size 2000mu . The water soluble high viscosity thickening agent is hydroxyethylcellulose; the plasticiser/coalescing agent is 2,2,4-trimethyl- 1,3-pentanediol monoisobutyrate; the acidic catalyst is AlCl3; and the cellulosic fibres are from soft and/or hard wood fibres, forming an adhesive gel having a viscosity as prepd. (Brookfield RVF, no.6 spindle at 25[deg]C) at 2 rpm of 30500-47000 cP and at 20 rpm 14500-25500 cP.
Patent NZ-280244-A (NZ)
Title: Flame-retardant and fabric-softening composition comprising a tetrakis(hydroxyorgano)phosphonium salt, an organic nitrogen compound and aliphatic hydroxyl-reactive compound
Inventor: LEI XIAO PING
IPC: D06M13/325
Filed: 1995-10-16
Abstract: A one-pack composition conferring flame-retardant and fabric-softening properties on fabrics comprises a THP<+> salt, an organic nitrogen compound (eg urea) and a hydroxyl-reactive organic compound having 12 or more carbon atoms. Preferred examples of such compounds include C12 amine, C18 amine and tallow amine (viz a C16 / C18 / C20 amine mixture).
Patent NZ-286247-A (NZ)
Title: Window stay comprises a sliding means moves along a stay and is lockable in set positions
Inventor: KONDEV KOSTADIN BORIS
IPC: E05C17/28
Filed: 1996-03-22
Abstract: A window stay for the mounting of a window sash in a window frame. The window stay includes a sliding element 14. A lock mechanism enables the sliding element 14 to be located and locked in at least one locking position on the stay element 10. The locking mechanism has a latching portion 31 which is engagable with at least one engagement part 35 of the stay element 10 and an actuating part 30 which enables the latching portion 31 to be disengaged from the engagement part 35 to enable the sliding element 14 to slide along the stay element 10. There are also a re-latching means 34 which cause the latching portion 31 to re-engage with the or a said engagement part 35 upon the sliding element 14 reaching the or a locking position.
Patent NZ-334305-A (NZ)
Title: Embankment wall having a slope angle of 30 to 75 degrees, made up of precast modules
Inventor: FORSBERG PAUL J
IPC: E02D17/20
Filed: 1995-08-24
Abstract: A precast construction module is to be used with a plurality of other modules to form a row and a plurality of rows to form an embankment wall having a slope angle of less than ninety degrees.  Each module has spaced top and bottom surfaces each having a front edge and a front face 30 having top and bottom edges extending between the top and bottom surfaces such that the top edge coincides with the top surface front edge and the bottom edge coincides with the bottom surface front edge.  The front face 30 forms a face angle with the bottom surface such when that the plurality of modules are arranged in a plurality of rows positioned one on top of the other in a set back position, the front faces of the modules in adjacent rows mate with each other to form a continuous wall face at the slope angle.
Patent NZ-501347-A (NZ)
Title: Tubular conveyor with discharge valve being tube section rotated about longitudinal axis by air cylinder, rack and annular gear wheel
Inventor: MCGOUN PETER
IPC: B65G19/14
Filed: 1998-05-28
Abstract: A tubular slow speed drag or aero-mechanical conveyor assembly is disclosed for transporting particulate material, and includes a tubular valve (11) positioned in line with conveyor tubes of the assembly and rotatable relative thereto. The valve (11) has at least one elongate aperture (21) through which particulate material can leave the assembly and means (24, 25) are provided for sequentially rotating the tubular valve (11) between positions in which the at least one aperture (21) is in the open or closed position of the valve (11). In one arrangement the rotation imparting means comprises an air cylinder (23) operable to impart linear movement to a gear rack (24) which meshes with and imparts rotational movement to an annular gear wheel (25) carried by the tubular valve (11).
Patent NZ-502726-A (NZ)
Title: Reclosable zipper, for a plastics bag, comprising a fulcrum formed to disengage interlocking members
Inventor: MACHACEK ZDENEK
IPC: B65D33/25
Filed: 2000-02-07
Abstract: A slide zipper assembly comprising a reclosable zipper and a slider is provided. The zipper includes a first profile interlockable with a second profile. The profiles include portions which form a fulcrum about which the profiles may be pivoted to disengage the profiles. The slider straddles the zipper and has a top from which two arms depend. The inner surface of one or both of the slider arms is shaped so that as the slider is moved along the zipper in an opening direction, one or both of the profiles is pivoted about the fulcrum so as to disengage the profiles.
Patent NZ-502844-A (NZ)
Title: Solid oxide fuel cell with silver cathode side current conductive layer
Inventor: JAFFREY DONALD
IPC: H01M8/0243
Filed: 1998-09-04
Abstract: A solid oxide fuel cell assembly has a gas separator plate (122) and a silver electrically conducting layer (136) disposed between the gas separator plate (122) and the cathode layer of the fuel cell. In one embodiment, the silver layer (136) is in the form of a mesh that permits oxygen-containing gas in the oxygen-containing gas channels access through the silver layer (136) to the cathode layer. The silver layer (136) abuts heads (138) of electrically connecting links (142) through the gas separator plate (122) to pass electric current collected by the silver layer (136) to a nickel mesh (144) on the anode side of the plate. The gas separator plate (122) has an alumina layer on the cathode side and may be formed of stainless steel. The silver may be at least substantially pure or alloyed, or it may be present as an intermediate compound or as a composite material with a non-metal. The silver layer may be formed on a substrate material such as stainless steel.
Patent NZ-508671-A (NZ)
Title: Gene therapy vectors for sensitising cancer cells and their use in antitumour therapy
Inventor: SCOTT SIMON
IPC: A61K48/00
Filed: 1999-05-17
Abstract: A vector material contains a tumour cell sensitizing gene or genes, a sensitizing gene expression regulatory system, at least one control gene and a control gene expression regulatory system. The tumour cell sensitizing gene or genes which when expressed in a tumour cell yield a sensitizing gene expression product having a potential to cause tumour cells to be killed and destroyed, or to be eliminated, or otherwise to be inactivated, or to be rendered sensitive and/or vulnerable to destruction. The sensitizing gene expression regulatory system, includes a promoter means, for the sensitizing gene or genes. The control gene expression regulatory system is responsive in use in a transfected cell to the effect of a predetermined exogenous or endogenous expression inducing influence so as to induce expression of the control gene to yield an expression product having a capacity to establish an operative linkage between the sensitizing gene expression regulatory system and the sensitising gene or genes effective to trigger and switch on or permit continuous or permanent expression of the latter to bring about continuous production of the sensitizing gene expression product. Also described is a pharmaceutical comprising the vector material that may be used in antitumour therapy.
Patent NZ-510385-A (NZ)
Title: E. coli enterotoxin II signal peptide and a microorganism expressing a fusion protein of the MST peptide and a heterologous protein, such as human growth hormone
Inventor: KWON SE CHANG
IPC: C12P21/02
Filed: 1999-09-15
Abstract: An E.coli enterotoxin II signal peptide shown below characterized in that at least one of the 2nd, 4th, 5th, 12th, 20th and 22nd amino acids is replaced by another amino acid, with at least either 2nd or 4th amino acids being lysine.  Also disclosed is a process for producing a heterologous protein in a microorganism comprising culturing a microorganism transformed with an expression vector (comprising a gene that encodes the E.coli enterotoxin II signal peptide) to produce and secrete the heterologous protein to periplasm and subsequently recovering the protein from the periplasm.
Patent NZ-516143-A (NZ)
Title: Process for the preparation of intermediate compounds of pharmaceuticals
Inventor: KUWABE SHIN-ITSU
IPC: C07D221/04
Filed: 2000-06-21
Abstract: The present invention relates to a process for preparing compound (I), (1S, 5S, 6R, 7R)-2-aza-7-chloro-5-methyl-3-oxobicyclo[4.1.0]heptane, by subjecting compound (II), (1S, 5S, 6R)-2-aza-7-chloro-5-methyl-3-oxobicyclo[4.1.0]heptane to selective crystallization and separation.
Patent NZ-516943-A (NZ)
Title: Medicaments that contain xenogenic oligo- or/and polyribonucleotides (RNA) for treating herpesviridae or skin tumors
Inventor: SEINFELD HUGO
IPC: A61P31/22
Filed: 2000-08-24
Abstract: A composition consisting essentially of xenogenic oligo- and/or  polynucleotides can be used to produce an  anhydrous medicament  for  the  topical  treatment  of  infections  by Herpesviridae and/or skin tumors.
Patent NZ-517788-A (NZ)
Title: Quinuclidine compounds and drugs containing the same as the active ingredient
Inventor: OKADA TOSHIMI
IPC: A61K31/506
Filed: 2000-09-27
Abstract: A compound of formula (I). R1 represents a hydrogen, or hydroxyl group. HAr represents aromatic heterocycle which may be substituted with 1 to 3 groups. Ar represents an optionally substituted aromatic ring. W represents a chain represented by: -CH2=CH2 which may be substituted, -CH=CH- which may be substituted, -C=C-, -CO-NH-, -NH-CH2, -CH2=NH-, -CH2-CO-, -CO-CH2-, -NH-S(O)1-, -S(O)1-NH-, CH2-S(O)1, -S(O)CH2; where 1 denotes 0, 1, or 2. X represents a chain represented by (1) a single bond, (2) an optionally substituted C1-6 alkylene chain, (3) an optionally substituted C2-6 alkynylene chain, (5) a formula -Q- (wherein Q represents oxygen, sulfur, CO or N(R2), where R2 represents a C1-6 alkyl group or a C1-6 alkoxy group, (6) -NH-CO-, (7) -CO-NH-, (8) -NH-CH2, (9)-CH2NH-, (10) _CH2_-CO-, (11) -CO-CH2-, (12) -NH-S(O)m-, (13) -S(O)m- NH, (14) -CH2S(O)m, (15) S(O)mCH2- (where m denotes 0, 1 or 2), or (16) -(CH2)n-O- (where n denotes an integer from 1 to 6). The compounds may prevent or treat a disease where inhibition of squalene synthesising enzyme is efficacious, such as hyperlipidaemia.
Patent NZ-518503-A (NZ)
Title: Methods of manipulating and sequencing nucleic acid molecules using transposition and recombination
Inventor: BRASCH MICHAEL A
IPC: C12Q1/68
Filed: 2000-10-25
Abstract: Disclosed are methods, kits and compositions for use in manipulating nucleic acid molecules, particularly cloning, sequencing, amplifying and mutating such molecules. Particularly disclosed is the use of integration sites comprising at least one recombination site or portion thereof and recombinational cloning to manipulate, select and analyze nucleic acid molecules of interest.
Patent NZ-523737-A (NZ)
Title: Hydrocarbon trap/catalyst composition
Inventor: ANDERSEN PAUL JOSEPH
IPC: F01N3/28
Filed: 2001-07-20
Abstract: An automotive exhaust system comprising a catalyst structure. The structure comprises a substrate including one or more catalyst layers where one of the catalysts layers comprises a hydrocarbon trap/catalyst composition. The composition consists of a hydrocarbon-adsorbing material and at least one metal (selected from lithium, sodium, potassium, rubidium and caesium. The metal is impregnated on the material.
Patent NZ-526378-A (NZ)
Title: Nucleic acid fragments encoding floral development proteins in plants and seeds
Inventor: CAHOON EDGAR B
IPC: C12N15/29
Filed: 2001-11-21
Abstract: An isolated nucleic acid fragment encoding floral development proteins, more specifically a FT homolog. Also disclosed is the construction of a recombinant DNA construct encoding all or a portion of the floral development proteins, In sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels of FT in an isolated transformed host cell.
Patent NZ-530198-A (NZ)
Title: Tetrahydroquinoline derivatives
Inventor: VAN STRATEN NICOLE CORINE RENE
IPC: C07D405/12
Filed: 2002-06-25
Abstract: A tetrahydroquinoline derivative compound according to formula 1 is disclosed. Pharmaceutical compositions comprising compounds of formula 1 are also described. The compounds are useful in the manufacture of a medicament for the control of fertility or the treatment of hormone-dependent disorders. The hormone dependent disorders may include breast cancer, prostate cancer and endometriosis. The described medicament may inactivate the FSH-receptor.
Patent NZ-534463-A (NZ)
Title: Process for preparing 3-(2-(4-(6-fluorobenzo(d) isoxazol-3-yl)-piperidin-1-yl)-ethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido-(1,2-a) pyrimidin-4-one
Inventor: FOGUET RAFAEL
IPC: A61P25/18
Filed: 2003-03-03
Abstract: A process for the preparation of 3-{2-[4-(6-fluorobenzo [d] isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-4H-pyrido-[1,2-a] pyrimidin-4-one of formula (I) is disclosed, wherein the process comprises: condensation of (2-methyl-4-oxo- 6,7,8,9-tetrahydro-4H-pyrido-[1,2-a] pyrimidin-3-yl)- acetaldehyde of formula (II) with 6-fluoro-3- (4-piperidinyl)-1,2-benzisoxazole of formula (IV) or any of its salts to provide the intermediate enamine 3-{2-[4-(6-fluorobenzo [d] isoxazol-3-yl)-piperidin-1-yl]-vinyl}-2-methyl-6, 7,8, 9-tetrahydro-pyrido[1, 2-a] pyrimidin-4-one of formula (III) followed by reduction of same in the presence of a hydride, optionally in the presence of a salt, acid or inorganic base, and in the presence of a suitable inert solvent, the reactions being performed by either isolating intermediate (III) or not in a single-stage synthesis process. The compound of formula (I) is also known as risperidone, which is a pharmaceutically active compound for its antipsychotic properties.
Patent NZ-538397-A (NZ)
Title: Storage venting device with filter, fan and by-pass pressure relief valve
Inventor: ELLERY CLIFFORD COLIN
Filed: 2005-02-22
Abstract: The venting device is connectable to a milk vessel or silo (not shown) and has one or more inlet filters 4, fan 5 and outlet 6. A pressure by-pass valve 7 is also provided.
Patent NZ-539092-A (NZ)
Title: Panel with trefoil arch shaped ridge or upward/outward form
Inventor: MCCLEW IAN KURT
Filed: 2005-03-24
Abstract: A panel of a sheet material is disclosed having at least one ridge or similar form (1) provided therein, the ridge or similar form (1) having substantially a trefoil arch type shape (2, 3, 4) in section. This section is such that the outer regions of the trefoil rise sharply from adjacent flanking sheet material and the central region of the trefoil rises from the outer regions. Such a trefoil arch type shape (2, 3, 4) in section is stated to provide improved resistance to plastic deformation and/or a distinctive aesthetic advantage.
Patent NZ-544625-A (NZ)
Title: Fluid transfer device having removable needle cartridge
Inventor: COHEN NAHUM
IPC: A61M5/00
Filed: 2004-06-17
Abstract: A fluid transfer device using a removable cartridge (102) comprising of a plurality of needles (114) is disclosed. The action of the device comprises of three steps. First the main housing spring (222) is compressed and the next needle (114) in the cartridge (102) is selected. Secondly, when the safety latch (108) is pressed downward the main housing spring (222) is allowed to expand causing the syringe (210) to advance and engage with the needle (114), translating the needles position within the cartridge (102) to its deployment position and compressing its individual spring (200). At the same time a predetermined amount of fluid is drawn into the reservoir (204) through a one way valve (206). Thirdly, pressing the piston pusher (214) then expels the fluid from the reservoir (204) though a second one way valve (208), into the syringe (210), needle (114) and then subject. As the device is primed for the next injection the syringe (210) is pulled back from the cartridge (102) and the needle (114) is then withdrawn by way of the expansion of its compressed spring (200). The needle (114) is prevented from reuse by a mechanism within the cartridge.
Patent NZ-545317-A (NZ)
Title: Cyclic derivatives as modulators of chemokine receptor activity
Inventor: BATT DOUGLAS G
IPC: C07D417/14
Filed: 2004-08-20
Abstract: Disclosed is a compound of Formula (Ia) or a stereoisomer or a pharmaceutically acceptable salt thereof. Also disclosed is a pharmaceutical composition, comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of the said compound. The use of the said compound in the preparation of a medicament for treating disorders, said disorders being selected from osteoarthritis, aneurism, fever, cardiovascular effects, Crohn's disease, congestive heart failure, autoimmune diseases, HIV-infection, HIV-associated dementia, psoriasis, idiopathic pulmonary fibrosis, transplant arteriosclerosis, physically- or chemically-induced brain trauma, inflammatory bowel disease, alveolitis, colitis, systemic lupus erythematosus, nephrotoxic serum nephritis, glomerularnephritis, asthma, multiple sclerosis, artherosclerosis, rheumatoid arthritis, restinosis, organ transplantation, and cancer is also disclosed.
Patent NZ-546630-A (NZ)
Title: Use of agomelatine in obtaining medicaments intended for the treatment of bipolar disorders
Inventor: DE BODINAT CHRISTIAN
IPC: C07C233/18
Filed: 2006-04-19
Abstract: Disclosed herein is a use of agomelatine, or N-[2-(7-methoxy-1-naphthyl)ethyl]acetamide, and also its hydrates, crystalline forms and addition salts with a pharmaceutically acceptable acid or base, in obtaining a medicament intended for the treatment of bipolar disorders. Also disclosed are compositions comprising agomelatine or one of its hydrates, crystalline forms and addition salts with a pharmaceutically acceptable acid or base, and a thymoregulatory agent such as lithium or valproate.