baber/WOPTO huggingface dataset:
Patent CY-1124472-T1 (CY)
Title: Κατασκευασματα διειδικων αντισωματων που δεσμευουν dll3 και cd3
Inventor: RAUM TOBIAS
IPC: C07K16/28
Filed: 2021-08-31
Abstract: Η παρούσα εφεύρεση αναφέρεται σε ένα κατασκεύασμα διειδικών αντισωμάτων που περιλαμβάνει μια πρώτη επικράτεια δέσμευσης που συνδέεται με ανθρώπινο DLL3 στην επιφάνεια ενός κυττάρου στόχου και μια δεύτερη επικράτεια δέσμευσης που συνδέεται με ανθρώπινο CD3 στην επιφάνεια ενός Τ κυττάρου. Επιπλέον, η εφεύρεση παρέχει ένα πολυνουκλεοτίδιο που κωδικοποιεί το κατασκεύασμα αντισώματος, έναν φορέα που περιλαμβάνει το εν λόγω πολυνουκλεοτίδιο και κύτταρο ξενιστή μετασχηματισμένο ή επιμολυσμένο με το εν λόγω πολυνουκλεοτίδιο ή φορέα. Περαιτέρω, η εφεύρεση παρέχει μια διαδικασία για την παραγωγή του κατασκευάσματος αντισώματος της εφεύρεσης, μια ιατρική χρήση του εν λόγω κατασκευάσματος αντισώματος και ένα κιτ που περιλαμβάνει το εν λόγω κατασκεύασμα αντισώματος.
Patent GR-960300053-T1 (GR)
Title: Proportional valve
Inventor: SCHMIDT KLAUS
IPC: F16F9/348
Filed: 1996-09-30
Abstract: The pressurised compartment (20) is defined by the damping valve disc (9, 10), an elastic element (11, 12), and by the wall-parts of the piston (1) and or of the piston insertion rings containing the orifices in the bypass-duct system. The elastic element of the pressurised compartment belonging to the opposite-facing operating compartment seals the pressure chamber from the appropriate operating chamber, when the pressure in the pressure chamber is higher than the operating compartment. The elastic element is opened by the pressure of the medium occurring in the opposite facing operating compartment, when the pressure of the medium exceeds the pressure in the pressure chamber.
Patent HR-P20110461-T1 (HR)
Title: Flag heat exchanger
Inventor: DETHIER ALFRED
IPC: F24S23/00
Filed: 2011-06-17
Abstract: The device has a ceramic central cover, and a flag shaped elementary exchanger including exchanger tubes that are connected to an inlet manifold (5) and an outlet manifold (6), respectively. The exchanger tubes are superposed for blocking incident radiation. Each tube is in the form of hairpin with a loop (4) at its pinhead and two joined branches (2, 3) that are superposed in a vertical manner, where an end of the tube at the level of the pinhead is free. The tubes are self-supported at their ends connected to the manifolds.
Patent HR-P20110831-T1 (HR)
Title: Polymer-based sustained release device
Inventor: WRIGHT STEVEN G
IPC: A61K31/573
Filed: 2011-11-11
Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
Patent SI-1356496-T1 (SI)
Title: Apparatus for evaporation of materials for coating objects
Inventor: HOLUBAR PAVEL
IPC: H01J37/00
Filed: 2001-12-14
Abstract: Apparatus for evaporation of materials for coating of objects by a physical method (PVD) using low voltage electric arc, such apparatus being equipped with a source (4a, 4b, 4) of magnetic field and an anode (3) and a cathode (2a, 2b, 2) of electric arc. At least one cathode (2a, 2b, 2) and at least one source (4a, 4b, 4) of magnetic field can pivot in the coating chamber (1).
Patent SI-1420827-T1 (SI)
Title: 5-cnac as oral delivery agent for parathyroid hormone fragments
Inventor: AZRIA MOISE
IPC: A61K38/00
Filed: 2002-08-16
Abstract: Pharmaceutical compositions for the effective oral delivery of a parathyroid hormone, PTH, as well as methods for administration of the compositions are provided. Additionally, methods for stimulating new bone formation and treating and/or preventing osteoporosis are also provided.
Patent SI-1663963-T1 (SI)
Title: Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
Inventor: REBIERE FRANCOIS
IPC: C07C315/02
Filed: 2004-09-17
Abstract: The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of :  a) contacting a pro-chiral sulphide of formula (II) with a metal chiral complex, a base and an oxidizing agent in an organic solvent ; and optionally b) isolating the obtained sulphoxide of formula (I). <CHEM>  wherein n, Y, R1, R1a, R2 and R2a are as defined in claim 1.
Patent SI-2230350-T1 (SI)
Title: Polymer fiber, its use and process for its manufacture
Inventor: KNACK INGO DR
IPC: C04B16/00
Filed: 2009-03-18
Abstract: The present invention relates to a novel polymer fiber obtainable by melt-spinning of a polymer, the use of the fiber and a process for the manufacture of the fiber.
Patent TR-200101918-T1 (TR)
Inventor: KANETO KIMIKAZU
IPC: B22C15/08
Filed: 2000-11-02
Abstract: A sand hopper (28) is provided at its lower position (40) with a plurality of nozzles (42) and a plurality of squeeze feet (46), the pressure of which is controlled, and which are located adjacent to a side of each squeeze foot. The sand hopper (28) is supported by supporting means (22, 26) such that it can move vertically. A mold space is defined by a pattern plate having a pattern (74a), a flask (4), a filling frame (52), and a sand hopper (28) having a plurality of squeeze feet (46) disposed above the filling frame (52). By discharging molding sand from the nozzles (42), it is introduced into the mold space. The mold sand (S2) in the mold space is compacted by the squeeze feet by lowering the sand hopper toward the mold space. Since the molding machine is so arranged, both introducing molding sand into a mold space and compacting the introduced molding sand are performed at one station (a molding-sand introducing and compacting station). <IMAGE>
Patent TR-200300614-T1 (TR)
Title: Kapağı kayma ve öteleme hareketi ile açılabilen çamaşır makinası.
Inventor: KUTLAY ENGIN
IPC: D06F39/14
Filed: 2001-08-07
Abstract: Çamasir makinasi yikama birimlerini içeren bir gövde (2) ve bir kapaktan (3) olusmaktadir. Ayrica çamasir makinasinda (1), bir spiral yay ve bir mil (5) ile beraber bir ucundan gövdeye (2), diger ucundan da kapagin (3) kenarlarina tutturulmus kapagin (3) hareketini saglayan kaldirma kollari (4) ve kapagin (3) hareketi sirasinda kapattigi yüzeye paralel olarak hareket etmesini saglayan, bir ucundan gövdeye (2), tercihan kaldirma kollarinin baglanti noktasindan daha asagiya sabitlenmis amortisörlü kilavuz kollari (6) da bulunmaktadir. Kaldirma kollari (4) ve kilavuz kollar (6) kapagin (3) kayarak ve ötelenerek açilmasini saglamaktadir.
Patent TR-200300792-T1 (TR)
Inventor: TESKY FRANK-MICHAEL
IPC: A47K10/42
Filed: 2001-12-15
Abstract: The dispenser for moist toilet paper comprises a box (1) with a frame (3) which snap fits over its upper lip. A hinged lid (4) is mounted on the rear of the frame which snap fits over it when shut. Frame and lid are fitted with peripheral sealing strips (7, 8).
Patent GR-20010300015-T1 (GR)
Title: Locking system and flooring board
Inventor: PERVAN DARKO
IPC: E04F15/04
Filed: 2001-04-30
Abstract: The invention relates to a locking system for mechanical joining of floorboards (1) along a vertical joint plane (F), and a floorboard comprising such a locking system. For joining perpendicular to the joint plane (F) there is a locking groove formed in the underside (3) of a first joint edge at a distance from the joint plane (F), and a portion (P) projecting from the lower part of the second joint edge (4a) and below the first joint edge and, at a distance from the joint plane (F), supporting a locking element (8) cooperating with the locking groove (14), said projecting portion (2) thus being located entirely outside the joint plane (F). The projecting portion (P) presents at least two horizontally juxtaposed parts (P1, P2), which differ from each other in respect of at least one of the parameters material composition and material properties.
Patent DE-3689762-T2 (DE)
Inventor: NISHIMURA TATSUO
IPC: C07D498/04
Filed: 1986-12-09
Granted: 1994-08-18
Abstract: A compound of the general formula:wherein R° is hydrogen, a nitrogen-containing heterocyclic group, an acyl group or an amino-protective group; A is S, S → O, O or CH<sub>2</sub>; R<sup>4</sup> is hydrogen, methoxy group or formamido group; R<sup>13</sup> is hydrogen, methyl, hydroxyl or a halogen; and A is an optionally substituted condensed cyclic group formed by combining an imidazole or pyrazole ring with a 5- or 6-membered nitrogen-containing aromatic heterocyclic ring to share a C-N bond with each other, or a salt or ester thereof. And a process for preparing the same and a pharmaceutical composition thereof are disclosed.
Patent DE-3852966-T2 (DE)
Inventor: SCHMIDT DONALD L
IPC: C09K23/52
Filed: 1988-05-11
Granted: 1995-05-24
Abstract: This invention relates to a water-soluble, crosslinkable polymeric surfactant having fluorocarbon and ionic moieties. Such surfactant can be cured into tough, solvent resistant, low critical surface tension coatings useful for protective finishes on metal, plastics and fabrics. This surfactant has (1) at least one pendant fluorocarbon moiety and (2) at least one pendant ionic moiety which is capable of reacting with a counterion to form a crosslinked polymer. The reactive ionic moieties on the polymer chain can be anionic, cationic or zwitterionic (having an equivalent amount of both cationic and anionic moieties).
Patent DE-3856540-T2 (DE)
Inventor: PALL DAVID B
IPC: B01D39/00
Filed: 1988-10-20
Granted: 2003-06-05
Abstract: Devices for the depletion of leukocytes in blood products, preferably comprising an upstream porous element including means for removal of gels, at least one intermediate porous element including means for removal of microaggregates, and a downstream element including means for removal of leukocytes by both adsorption and filtration, preferably with at least one of the elements having been modified to a CWST in excess of 53 dynes/cm. <IMAGE>
Patent DE-3882669-T2 (DE)
Inventor: DEAN WALTER CLARK
IPC: G03G15/02
Filed: 1988-12-07
Granted: 1993-11-04
Abstract: A belt conditioner for non-impact electrographic printing apparatus using a flexible dielectric belt (10) including a conductive member forming a ground plane (51) opposite the dielectric surface (52) has plural electrically conductive rollers (40, 41) engaging the dielectric charge receiving surface (52) to effect controlled discharge of the surface to a uniform surface electrostatic voltage before direct charge deposition by a print head (14) to form a latent electrostatic image. Corona discharge devices (35, 36, 37) can also be utilized with the rollers (40, 41) to obtain the desired belt conditioning.
Patent TR-199900982-T2 (TR)
Inventor: JOHANSSON INGEGARD
IPC: C11D1/16
Filed: 1997-11-20
Abstract: R'nin 6-20, tercihen 8-16 karbon atomuna sahip bir alifatik hidrokarbon grubunu, G'nin bir sakkarit tortuyu, A'nin 2-4 karbon atomuna sahip bir oksialkileni veya 3-oksi-2-hidroksi propileni, n'nin  1 ila 10, tercihen 1 ila 4 arasinda bir sayiyi ve s'nin ise 0 ila 5 arasinda bir sayiyi simgeledigi, R(A)s(G)n formülündeki glikozit tabanli bir anyonik türevin ya da içerisindeki adaktin formül 1'de verilen bir glikozite dayandirildigi ve alkilen oksitin 2-4 karbon atomu içerdigi, iyonik olmayan bir alkilen oksit adaktin eklenmesi, formül 1'deki bir glikozitin bir sulu kristalizasyonunu önlemekte ve engellemektedir. Türevin veya addaktin eklenmesi glikozit özelliklerinde oldukça küçük degisikliklere yol açmaktadir.
Patent TR-199901518-T2 (TR)
Inventor: GUPTA AJAY
IPC: A61P7/08
Filed: 1997-12-30
Abstract: A method of administering iron to dialysis patients is accomplished by infusion of a noncolloidal ferric compound, soluble in hemodialysis or peritoneal dialysis solutions, by the process of dialysis. A pharmaceutical composition is provided consisting essentially of dialysis solution including a soluble noncolloidal ferric compound, preferably ferric pyrophosphate.
Patent TR-199901721-T2 (TR)
Inventor: MARUANI JEANNE
IPC: A61K31/415
Filed: 1998-01-28
Abstract: Bu bulus, CB1 reseptör antagonistlerinin, istah bozukluklarinin tedavisi için uygun ilaçlarin hazirlanmasinda kullanimina iliskindir. Istah bozukluklarinin tedavisi için uygun ilaçlarin amaci, tüketim arzusunu, özellikle de seker, karbonhidratlar, alkol veya uyusturucular ve daha genel olarak istah verici maddere karsi olan tüketim arzusunu ayarlamaktir.
Patent TR-199903278-T2 (TR)
Inventor: REVESZ LASZLO
IPC: C07D401/14
Filed: 1998-06-26
Abstract: Yeni 2-substitüte 4,5-diaril imidazoller. Bu imidazollerde: i) 1. pozisyondaki azot atomu trialkilsilil içeren bir substitüent ile yer degistirir veya ii) 2. pozisyondaki substitüent arilalkil, arilsulfonil, ariltiyo arilseleno, ariltellüro, siklokalkil, siklokalkenil, alkilsikloalkil, alkilsikloalkenil, amino veya hidrazino veya N içeren halkanin alti üyeye sahip oldugu mono- veya bisiklik N-heterosiklildir. Bunlar Formül I' in özel bilesiklerinde saglanir. (Formül(I)); Burada R1, R2, R3 ve R4 serbest veya farmasötik olarak kullanilabilir asit ekleme tuzu veya fizyolojik olarak bölünebilir ester formunda tanimlandigi gibidir ve p38 MAP kinaz (Mitojen Aktive Protein Kinaz) inhibisyon aktivitesine sahiptir.
Patent AT-E273561-T2 (AT)
Inventor: KRUTCHINSKY ANDREW N
IPC: H01J49/42
Filed: 1999-01-25
Granted: 2004-08-15
Abstract: A method and apparatus are provided for providing an ion transmission device or interface between an ion source and a spectrometer. The ion transmission device can include a multipole rod set and includes a damping gas, to damp spatial and energy spreads of ions generated by a pulsed ion source. The multipole rod set has the effect of guiding the ions along an ion path, so that they can be directed into the inlet of a mass spectrometer. The invention has particular application to MALDI (matrix-assisted laser desorption/ionization) ion sources, which produce a small supersonic jet of matrix molecules and ions, which is substantially non-directional, and can have ions travelling in all available directions from the source and having a wide range of energy spreads. The ion transmission device can have a number of effects, including: substantially spreading out the generated ions along an ion axis to generate a quasi-continuous beam; reducing the energy spread of ions emitted from the source; and at least partially suppressing unwanted fragmentation of analyte ions. Consequently, a number of pulses of ions can be delivered to the time-of-flight or other spectrometer, for each cycle of the ion generation.
Patent DE-60007782-T2 (DE)
Inventor: PETERS HENDRICUS
IPC: C07D211/22
Filed: 2000-05-12
Granted: 2004-12-09
Abstract: The tosylate ester of the formula (6) and its salts, are convenient intermediates in the synthesis of paroxetine.
Patent DE-60007930-T2 (DE)
Inventor: BELVEZE FABRICE JEAN-ANDRE
IPC: H04L7/02
Filed: 2000-08-31
Granted: 2004-10-28
Abstract: The method involves evaluating a difference between first frequency modulation for the emitted signal, and a second modulation frequency used by the receptor to create an emitted signal from a received signal. Once the difference is determined, the result is used to synchronize the signals. An Independent claim is also included for a synchronization apparatus suitable for executing the method.
Patent DE-60009313-T2 (DE)
Inventor: MISSELBROOK JOHN
IPC: A01N43/58
Filed: 2000-08-25
Granted: 2005-03-10
Abstract: The invention relates to novel compositions of biologically active agents containing less than 50% by weight of a low use rate agrochemical active and a dispersing agent, which exhibit enhanced bio-availability on dilution and application in water.
Patent DE-60010198-T2 (DE)
Inventor: HILPERT HANS
IPC: C07C29/32
Filed: 2000-10-13
Granted: 2004-12-16
Abstract: A new process prepares retiferol derivatives of formula I:whereinA is -C =C- or -CH=CH-, andR1 and R2 are independently of each other lower alkyl or lower perfluoroalkyl, one version couples ketones of formula 1I with compounds of formula IIIA second version couples phosphinoxides of formula IV with aldehydes of formula V. Compounds of formula I are useful in the treatment or prevention of hyperproliferative skin diseases and for reversing the conditions associated with photodamage.
Patent DE-60014575-T2 (DE)
Inventor: BENVENUTO EUGENIO
IPC: C07K19/00
Filed: 2000-12-21
Granted: 2005-10-13
Abstract: Object of the present invention are peptides which stabilize antibodies including them even in a reducing medium, in particular cytoplasmic medium, the polypeptides which include at least one of the above mentioned peptides, antibodies which include these polypeptides, and polynucleotides coding for peptides, polypeptides and antibodies of the invention. <IMAGE>
Patent DE-60022769-T2 (DE)
Inventor: ZHU YUN-FEI
IPC: A61P17/00
Filed: 2000-10-16
Granted: 2006-07-06
Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have structure (I): wherein Ar, A, B, Q, R1, R2, R3a, R3b, R6, R7 and <i>m</i> are as defined herein, including stereoisomers, prodrugs and pharmaceutical acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
Patent DE-60031424-T2 (DE)
Inventor: OHMI TADAHIRO
IPC: H05K3/46
Filed: 2000-08-11
Granted: 2007-08-30
Abstract: The present invention has an object to provide a producing method and producing apparatus of multilayered printed-circuit board that has eliminated the resin flow and resolved the problems of board thickness discrepancy and misregistration. A producing method of multilayered printed-circuit board , comprising steps of stacking up a laminated sheet covered with conductive foil or conductor for outer layer, a prepreg and a laminated sheet covered with conductor for inner layer and, thereafter, setting the prepreg by pressurizing/heating, wherein, before conducting the pressurizing/heating, gas is sprayed to the surface of the laminated sheet covered with conductive foil or conductor for outer layer, a prepreg and a laminated sheet covered with conductor for inner layer to eliminate impurities from the surface. <IMAGE>
Patent DE-60031444-T2 (DE)
Inventor: AMANO SHINSUKE
IPC: F25B9/14
Filed: 2000-12-18
Granted: 2007-08-23
Abstract: A Stirling refrigerating machine, comprising a regenerator provided in a flow path for a working medium reciprocating between an expansion space and a compression space formed in a cylinder, wherein a flow strengthener making uniform the flow of the working medium passing through the regenerator is provided on one or both of the expansion and compression space sides of the regenerator, whereby, because the nonuniformity of the flow of the working medium passing through the regenerator is improved, a regenerated heat exchanging efficiency can be increased, and thus the performance of the refrigerating machine can be increased. <IMAGE>
Patent DE-60032761-T2 (DE)
Inventor: KETRENOS P
IPC: G09G1/16
Filed: 2000-04-12
Granted: 2007-10-11
Abstract: Data intended to be displayed on a higher resolution display such as a non-interlaced display used as a computer monitor may be converted for display on a lower resolution display such as an interlaced display. The conversion may be done in a way that preserves the intended frame format while enhancing readability. For example, in one embodiment, the frames intended for non-interlaced display may be preserved in size for display in the same frame format on a lower resolution interlaced display. Local magnification may be selectively implemented for particular regions to enhance the readability of those regions. Upon selection, such local magnification may provide pixel loss and color corrections in addition to local magnification. In this way the frame format may be preserved while enhancing readability.
Patent DE-60033544-T2 (DE)
Inventor: SUNDHOLM GOERAN
IPC: A62C3/07
Filed: 2000-10-06
Granted: 2007-11-22
Abstract: The invention relates to an installation for extinguishing fire, the installation comprising a number of spray heads (330a, 380a), a pipe system (381) for leading extinguishing medium to the spray heads, which spray heads comprise a holder body having an inlet for incoming extinguishing medium and at least one nozzle. In order to be able to use the installation in conditions in which it can be strongly exposed to dirt and impurities and in order that it will not be activated on account of the spray heads of the installation being exposed to impacts or heat not coming from the seat of the fire, the installation is characterized in that the spray heads (330a, 380a) comprise a cover, which is positioned by means of a locking device in a protective position in front of said nozzle when the installation is in an inactive mode and which is, upon activation of the installation, arranged to be displaced to a free position, in which the cover is out of the way of said nozzle, the cover being arranged to be displaced to the free position when a fluid exerts a force against the locking device so that this opens.
Patent DE-60036906-T2 (DE)
Inventor: HLAVINKA DENNIS
IPC: B04B5/04
Filed: 2000-03-07
Granted: 2008-08-21
Abstract: An apparatus and method are provided for separating components of a fluid or particles. A separation vessel (28) having a barrier dam (62) is provided to initially separate intermediate density components of a fluid, and a fluid chamber (30) is provided to further separate these intermediate density components by forming an elutriative field or saturated fluidized particle bed. The separation vessel includes a shield (96) for limiting flow into the fluid chamber of relatively high density substances, such as red blood cells. The separation vessel also includes a trap dam (70) with a smooth, gradually sloped downstream section (104) for reducing mixing of substances. Structure is also provided for adding additional plasma to platelets and plasma flowing from the fluid chamber. The system reduces clumping of platelets by limiting contact between the platelets and walls of the separation vessel.
Patent DE-60104002-T2 (DE)
Inventor: IWASAKI-HIGBEE JEFFREY L
IPC: F16L55/164
Filed: 2001-03-12
Granted: 2005-08-18
Abstract: A method of repairing leaking underground pipes, particularly gravity-flow sewer pipes, without excavation, by using a flexible liner tube containing a fluid under sufficient pressure to exclude groundwater, while forcing a fluid sealant material into leaking defects in a pipe wall, and through openings in the pipe wall into voids outside the pipe. The flexible liner tube is everted into the pipe to keep the sealant material in place and also to continue to exclude groundwater for a period of time long enough for the sealant material to cure in place to effect sealing repair of the defects in the pipe wall and also at least partially fill voids outside the pipe. Fluid is kept under great enough pressure in the liner tube to exclude groundwater and may be heated or chilled to assist in preparing the pipe for sealant or to cure the sealant material.
Patent DE-60105411-T2 (DE)
Inventor: CHEN XU QI
IPC: C12Q1/6886
Filed: 2001-05-16
Granted: 2005-09-22
Abstract: Diagnosing and/or monitoring the evolution of cancers, comprising analyzing the ribonucleic acid (RNA) components of the enzyme telomerase in blood plasma or serum, is new.