baber/WOPTO huggingface dataset:
Patent CA-2840017-A1 (CA)
Title: Compounds for the treatment of cancers associated with human papillomavirus
Inventor: PIRAMAL SWATI AJAY
IPC: A61K31/4025
Filed: 2012-06-22
Abstract: The present invention relates to the pyrrolidine substituted with flavone derivatives, represented by the compounds of Formula (I) or a pharmaceutically acceptable salt, a solvate, a stereoisomer or a diastereoisomer thereof for use in the treatment of cancers associated with human papillomavirus. The present invention also relates to the pharmaceutical compositions containing the compounds of Formula (I) for the treatment of cancers associated with human papillomavirus.
Patent CA-2840373-A1 (CA)
Title: Compounds and methods of prophylaxis and treatment regarding nicotinic receptor antagonists
Inventor: PENG YOUYI
IPC: A61K33/243
Filed: 2012-06-22
Abstract: It is an object of the present invention that the novel nicotinic receptor antagonists disclosed herein may be used in a broad array of clinical or medicinal facets. For example, it is a contemplated use of the present invention that the novel nicotinic receptor antagonists be used to inhibit the growth cycle of non-small cell lung cancer cells. Without being bound by theory, it is an object of the present invention that the nicotinic receptor antagonists disclosed herein are believed to possess reversible binding properties. Moreover, the compounds of the present invention are selective for 0.7 nAChR. For example, the compounds of the present invention are not believed to bind to 0.4 (32 nAChR neuromuscular receptors. It is also contemplated that the nicotinic receptor antagonists of the present invention will be used as a counter measure to treat exposure, or potential exposure, to a wide array of potential neurotoxins.
Patent CA-2841610-A1 (CA)
Title: An ozone generator
Inventor: KALHOJ MARK
IPC: C01B13/10
Filed: 2012-07-13
Abstract: An ozone generator comprising an ultraviolet light source and a housing defining a space around the ultraviolet light source. The housing is configured to direct a gas comprising oxygen through an ozone generation zone in which the gas containing oxygen is exposed to ultraviolet light. The housing further at least partially define a non reaction zone wherein any gas or fluid is substantially stagnant and wherein the ultraviolet light source emit ultraviolet light through the non reaction zone.
Patent CA-2844070-A1 (CA)
Inventor: MCWIRTER JOHN
IPC: C12N9/64
Filed: 2012-08-03
Abstract: Mice, tissues, cells, and genetic material are provided that comprise a humanized heavy chain immunoglobulin locus, a humanized light chain locus that expresses a universal light chain, and a gene encoding an ADAM6 or ortholog or homolog or functional fragment thereof. Mice are provided that express humanized heavy chains comprising human variable domains, and that express humanized light chains comprising human variable domains wherein the light chains are derived from no more than one, or no more than two, light chain V and J or rearranged V/J sequences. Fertile male mice that express antibodies with universal light chains and humanized heavy chains are provided. Methods and compositions for making bispecific binding proteins are provided.
Patent CA-2844957-A1 (CA)
Title: Power generation device floating in the air
Inventor: CHEN CHIA-CHERN
IPC: B64B1/00
Filed: 2014-03-06
Abstract: A power generation device floating in the air includes a lifting device, a connection device and a ground device. The lifting device is consisted of plural buoyant units with solar cells and wind turbines respectively located on the top and lower portions thereof The connection device is connected between the lifting device and the ground device. The main functions of the ground device are power alternation, power distribution and power storage. The ground device is connected with power supply network in parallel in order to deliver power to users. The solar cells and the wind turbines are located in the air instead of on ground. The weather does not affect the efficiency of the power generation device.
Patent CA-2845058-A1 (CA)
Title: Extendable plow
Inventor: SUPERGAN MICHAEL
IPC: A01B15/02
Filed: 2014-03-07
Abstract: An extendable plow is disclosed. The extendable plow may include a transitional cutting edge disposed on a bottom edge of the center section, the transitional cutting edge allows moved material to transition from one plowing surface to another. The extendable plow may include a pair of compression springs coupled to the back facing of the center section of the extendable plow, the pair of compression springs to trip the extendable plow. The extendable plow may also include a center section with a side extension on each side of the center section that may be extended to a plurality of predetermined lengths to accommodate different sized work environments and move more material.
Patent CA-2846594-A1 (CA)
Title: Systems and methods for missing data imputation
Inventor: SARRAFZADEH MAJID
IPC: G16H50/30
Filed: 2012-08-27
Abstract: Congestive heart failure (CHF) is a leading cause of death in the United States. WANDA is a wireless health project that leverages sensor technology and wireless communication to monitor the health status of patients with CHF. The first pilot study of WANDA showed the system's effectiveness for patients with CHF. However, WANDA experienced a considerable amount of missing data due to system misuse, nonuse, and failure. Missing data is highly undesirable as automated alarms may fail to notify healthcare professionals of potentially dangerous patient conditions. Embodiments of the present disclosure may utilize machine learning techniques including projection adjustment by contribution estimation regression (PACE), Bayesian methods, and voting feature interval (VFI) algorithms to predict both non-binomial and binomial data. The experimental results show that the aforementioned algorithms are superior to other methods with high accuracy and recall.
Patent CA-2849031-A1 (CA)
Inventor: CALEFFI MARCO
IPC: B01D35/06
Filed: 2012-02-02
Abstract: A magnetic particle separator (10) suitable for separating magnetic and non-magnetic particles from a thermal fluid flowing in a heating system. The magnetic particle separator (10) comprises a hollow body (10A, 10B) configured with an upper particle separation chamber (11) and for circulation of the thermal fluid between an inlet and an outlet port (12, 13), and a quieting chamber (15) beneath the particle separation chamber (11) for accumulation of the particles separated from the fluid: an annular support element (21) for permanent magnets (18) being removably fastened outside the quieting chamber (15) of the separator (10).
Patent CA-2850909-A1 (CA)
Title: Method for leaching a sulphidic metal concentrate
Inventor: HAAKANA TIMO
IPC: C22B19/00
Filed: 2012-11-07
Abstract: A method for leaching a sulfidic metal concentrate in hydrometallurgical production of metal in a leaching process from which hot water vapor containing off-gas is conducted out and to which an acid solution warmed up to an elevated temperature is conducted. The acid solution is warmed up to an elevated temperature by bringing off-gas of the leaching step into direct con¬ tact with the acid solution.
Patent CA-2851717-A1 (CA)
Inventor: MAJEED MUHAMMED
IPC: A01N37/10
Filed: 2012-01-10
Abstract: The present invention discloses the potential of Calebin A in inhibiting adipogenesis and applications thereof in obesity management. The present invention elucidates the potential of Calebin A to favorably modulate biochemical markers associated with obesity. Notable biomodulatory properties of Calebin A include inhibiting leptin production, increasing adiponectin expression and inhibiting local (adipocyte) and systemic inflammation caused by pro-inflammatory cytokines Tumor Necrosis Factor (TNF-a), Interleukin-6 (IL-6) and Interleukin-1 (IL-1ß).
Patent CA-2852702-A1 (CA)
Title: Thermally conductive, metal-based bandages to aid in medical healing and methods of use
Inventor: FREER CARL
IPC: A61L15/18
Filed: 2012-07-11
Abstract: The inventive disclosure contained herein is generally directed to a class of medical bandages that in many embodiments are effective in the treatment of various types of tissue burns, whether be burns due to thermal burns, sun exposure, or rashes. Such products can include a plurality of specialized bandages and wraps that incorporate an extremely thin layer of thermally conductive metal (often aluminum) at the base of a substrate adapted to be in direct contact with a burn wound, while manufacturing the top side of the aluminum substrate to have a heat-dissipation-enhancing topography to help cool burns faster by enhancing thermal-convection properties. The bandage can also feature a thermochromic indicator for users to realize the thermal-cooling status of a burn to which a bandage has been applied.
Patent CA-2855073-A1 (CA)
Title: Method of using spatially independent subsets of data to calculate vertical trend curve uncertainty of spatially correlated reservoir data
Inventor: THORNE JULIAN
IPC: G16Z99/00
Filed: 2012-07-25
Abstract: A method, implemented on a computer, for calculating vertical trend curve uncertainty of spatially correlated reservoir data. The method includes inputting, into the computer, a sample reservoir data comprising correlated data; applying, using the computer, a variogram to the sample reservoir data to select a plurality of subsets of data, the subsets of data being substantially less correlated than the sample reservoir data; and applying, using the computer, a bootstrap process on each of the plurality of subsets of data to obtain a plurality of bootstrap data sets from each of the plurality of subsets of data. The method further includes calculating vertical trend curves for each of the obtained plurality of bootstrap data sets, ranking the vertical trend curves by using a selected statistical parameter to obtain ranked vertical trend curves, and characterizing the uncertainty based on the ranked vertical trend curves.
Patent CA-2856462-A1 (CA)
Title: Nozzle device for a furnace for heat treating a steel flat product and furnace equipped with such a nozzle device
Inventor: NORDEN MARTIN
IPC: F27D7/02
Filed: 2012-12-17
Abstract: A nozzle device for a furnace for heat treating a steel flat product has a central supply pipe with at least one nozzle opening and a feed connection for connecting the nozzle device to a gas supply. The gas supply feeds a gas into and through the nozzle device to the at least one nozzle opening. The nozzle device and the furnace ensure that the respective heat treatment produces uniform results. The nozzle device has a first section with a smaller effective nozzle opening cross-section than in a second section in a flow direction of the gas from the feed connection through the nozzle device.
Patent CA-2857876-A1 (CA)
Inventor: BEDFORD JONATHAN CHARLES
IPC: A63F3/06
Filed: 2014-07-29
Abstract: An array of interconnected lottery tickets incudes a first lottery ticket and a a second lottery ticket connected to the first lottery ticket along a common side edge.  The common side edge has a connected, manually detachable region that holds the first and second lottery tickets in an interconnected configuration, and a completely disconnected region.
Patent CA-2857897-A1 (CA)
Inventor: KELLY JAMES L JR
IPC: G06Q10/06
Filed: 2014-07-28
Abstract: A business rules batch processor is provided that includes a business rules manager that sends a plurality of pending requests to a rules database for processing. A business rules orchestrator receives statuses of the pending requests from the business rules manager. The business rules orchestrator manages the batch processing of the pending requests by assessing the rules database usage and job requirements of the pending requests.
Patent CA-2859269-A1 (CA)
Inventor: BAMFORD PASCAL
IPC: G06V10/56
Filed: 2013-01-29
Abstract: A computer-based specimen analyzer (10) is configured to detect a level of expression of genes in a cell sample by detecting dots that represent differently stained genes and chromosomes in a cell. The color of the stained genes and the chromosomes is enhanced and filtered to produce a dot mask that defines areas in the image that are genes, chromosomes, or non-genetic material. Metrics are determined for the dots and/or pixels in the image of the cell in areas corresponding to the dots. The metrics are fed to a classifier that separates genes from chromosomes. The results of the classifier are counted to estimate the expression level of genes in the tissue samples.
Patent CA-2859701-A1 (CA)
Inventor: WU JIE
IPC: F17D1/16
Filed: 2013-02-07
Abstract: A device for reducing friction of a viscous fluid flow in a conduit includes a body (10,110) positionable to define at least a segment of a flow path for the viscous fluid in or contiguous with the conduit, a cavity (40,140) in the body for retaining lubricating fluid, and at least one port (42,142) in the body for delivering lubricating fluid to the cavity. A fluid outlet arrangement (48,148) from the cavity delivers lubricating fluid to the flow path to form a downstream lubricating film about viscous fluid flowing therein. The fluid outlet arrangement comprises a substantially continuous opening or ring of close spaced openings about the flow path. The cavity comprises an array of passages in the body that includes a plurality of elongate passages (55,155) that extend about the flow path effective collectively to reduce the pressure variation and therefore velocity variation of the delivered lubricating fluid along the outlet arrangement. A corresponding method is also disclosed.
Patent CA-2860015-A1 (CA)
Title: Three-dimensional cavities of dendritic cell immunoreceptor (dcir), compounds binding thereto and therapeutic applications related to inhibition of human immunodeficiency virus type-1 (hiv-1)
Inventor: GILBERT CAROLINE
IPC: G16C20/64
Filed: 2012-12-20
Abstract: The invention is concerned with compounds, pharmaceutical compositions, screening methods, and therapeutic methods for preventing or reducing a human immunodeficiency virus type-1 (HIV-1) infection and/or propagation associated with dendritic cell immunoreceptor (DCIR). Described herein are compounds which bind on at least one three-dimensional cavity of the DCIR, the cavity(ies) being involved in the interaction between HIV-1 and DCIR. Also described are screening methods for identifying active inhibitors and method of using such inhibitors for the prevention or treatment of virus infections, and more particularly for reducing human immunodeficiency virus type-1 (HIV-1) binding, entry and/or replication in human cells.
Patent CA-2862517-A1 (CA)
Title: A method for fighting a fire or a temperature rise in a material stored in a large storage facility, a fire fighting system and uses hereof
Inventor: BERGHOLDT NATALIA VALENTINOVA
IPC: A62C99/00
Filed: 2012-01-24
Abstract: The invention relates to a method for fighting a fire or a temperature rise in a material stored in a large storage facility such as a silo or a similar closed storage building for a biomass material. The method comprising steps of detecting a fire or temperature rise in said stored material of the storage facility with detecting means, and applying liquid nitrogen to the interior of the storage facility from a fire fighting system in said facility wherein the amount of applied liquid nitrogen is controlled with control means in relation to one or more values of said facility and/or stored material. The invention also relates to a fire fighting system and uses of the method and fire fighting system.
Patent CA-2862584-A1 (CA)
Inventor: SAPENA SOLER FRANCISCO
IPC: H04L12/58
Filed: 2013-02-19
Abstract: The invention consists of a method so that a telecommunication operator can deliver data messaging, digitally sign it and deliver it to the user with a certificate.  The method has the following steps: -      creation of a data message through a user interface (1), -      delivery of the data message to the destination, -      reception of a delivery notification of the data message sent to the destination, creation in the data processing unit (5) of an electronic document that comprises at least issuing user data, date of issuance, content and delivery notification data of the message sent, -      implementation of a digital signature algorithm to the electronic document for the creation of a certificate, -      delivery of the certificate to the user through the mail server (4).
Patent CA-2863231-A1 (CA)
Title: Gear assembly and use in cylinder lock
Inventor: NAROVLANSKY BORIS
IPC: E05B47/06
Filed: 2013-02-06
Abstract: An assembly including a cylinder lock including a rotatable member for actuating an external locking element, and a reduction gear disposed inside the cylinder lock, the reduction gear mechanically linked to the rotatable member and operable to rotate the rotatable member, the reduction gear including an interface member for connection to an actuator for movement of the reduction gear.
Patent CA-2863442-A1 (CA)
Inventor: NGO THANH Q
IPC: G06F9/50
Filed: 2013-01-17
Abstract: Application instances can be virtualized and operate in a fault tolerant and load-balanced means across a cluster of servers while still maintaining access to a common pool of data. Each application instance is instantiated so to operate on top on top of a virtual host that possesses a distinct virtual Internet protocol address. Each node within a server cluster environment can possess one or more virtual hosts wherein upon server failover the virtual host and its associated virtual Internet protocol address can be relocated to another server without disturbing the instantiation of the application on the virtual host.
Patent CA-2864787-A1 (CA)
Title: Electrosurgical implement
Inventor: BROOKE GERARD MICHAEL
IPC: A61B18/00
Filed: 2013-02-18
Abstract: An electrosurgical implement comprises an elongate tubular body having an opening at a forward end; an electrode assembly comprising a treatment electrode through which a treatment current may be passed in use, the treatment electrode having a patient contact region at a forward end; the electrode assembly carried in said tubular body and being movable between a retracted position in which the patient contact region of the electrode is shielded within said elongate tubular body and at least one extended position in which said patient contact region projects through said opening; a bias arrangement for biasing said electrode assembly towards its retracted position, and a latch arrangement for latching said electrode assembly in said at least one extended position.
Patent CA-2866338-A1 (CA)
Title: Managing objects in a supply chain using a secure identifier
Inventor: SANNIER GAEL
IPC: G06Q10/08
Filed: 2013-03-13
Abstract: A system and method for authenticating an identity of an object being tracked while traversing a supply chain, which includes an interface communicating with object custodians in the supply chain using a standard protocol in which event tracking information for the object is stored when any one of the object custodians reports a predefined event for the object. The system and method also include a repository storing authentication data to authenticate the event tracking information for the object, the event tracking information including a first object identifier and a second object identifier, the second object identifier being independently authenticated from the first object identifier.
Patent CA-2866502-A1 (CA)
Inventor: HUANG HSU-SHAN
IPC: A61P35/00
Filed: 2014-10-03
Abstract: The invention provides a series of novel thiochromeno[2,3-c] quinolin-12-one derivatives. Further, the invention also provides the preparation method and application of said derivatives, said application comprises: said derivatives with treating effective amount are prepared into pharmaceutical compositions for inhibition of topoisomerase type I and II, inhibition of cancer cell growth, further treating cancer.
Patent CA-2866552-A1 (CA)
Inventor: INSERRA IMPARATO SABATO
IPC: B29C33/48
Filed: 2013-04-12
Abstract: A vacuum bag (18) is placed around the inner forming surface (IML) of an inner mandrel with radially retractable sectors (11a, 11b) having parallel longitudinal slots (17). Stringers (30) of composite material are positioned in the slots (17). A respective elongated inner support (31) is placed in each stringer, covered by an impermeable tubular bag (32). A skin (37) of composite material is laminated around the stringers (30), the coated supports (31, 32) and the inner forming surface (IML). An outer curing tool (50, 51) closes around the skin (37) defining an outer forming surface (OML) for the fuselage barrel, leaving an annular gap (G) of predetermined radial width between the outer surface of the skin (37) and the outer forming surface (OML). Vacuum is applied to the volume enclosed between the vacuum bag (18) and the outer tool (50, 51), so as to enlarge the diameter of the uncured barrel, causing the barrel to be released from the inner mandrel (10) and bringing the outer surface of the skin (37) into contact with the inner surface (OML) of the outer tool (50, 51).
Patent CA-2870974-A1 (CA)
Inventor: MARANDOLA ORLANDO JR
IPC: E04F21/00
Filed: 2014-11-12
Abstract: A tile installation tool comprising a base defining substantially opposed base first and second end edges and a longitudinal axis extending therebetween; and a screeding element including a central portion and first and second screeding protrusions extending therefrom away from the central portion along respectively first and second directions that are angled relative to each other, the first and second screeding protrusions having different dimensions perpendicularly to the first and second directions. The screeding element is mountable to the base in a first configuration and in a second configuration, the screeding element being substantially transversally substantially fixed relative to the base in both the first and second configurations and at least part of the first and second screeding protrusions protruding substantially longitudinally from the base first end edge with the screeding element selectively movable substantially longitudinally relative to the base in the first and second configurations respectively.
Patent CA-2872428-A1 (CA)
Inventor: LIU GUI-WEN
IPC: B25C1/04
Filed: 2014-11-27
Abstract: The present invention relates to a steam powered nailing gun. In certain embodiments, the steam powered nailing gun includes a handle, a casing, a high pressure water pump, a piston mechanism, a nailing gun base, and a nail magazine. The piston mechanism is connected to the casing. One end of the piston mechanism is connected to the high pressure water pump, and another end is connected to nailing gun base. The nail magazine is disposed at a position corresponding to piston mechanism on the nailing gun base. A phase transition thermal storage device and a steam power generator are positioned inside casing having steam power generator inside phase transition thermal storage device. The steam power generator is connected to high pressure water pump and piston mechanism. The high pressure water pump is further connected to a water supply device 11 on the handle through a second water supply pipe.
Patent CA-2872775-A1 (CA)
Inventor: GUTIERREZ SANTANA XIOMARA GRACIELA
IPC: C09K8/584
Filed: 2014-11-27
Abstract: A method for improving recovery from an oil-bearing subterranean formation includes the steps of: injecting a surfactant solution into the subterranean formation, wherein the surfactant solution comprises a mixture of fatty acids and salts of the fatty acids with a mild base, whereby oil-water interfacial tension in the formation is reduced; and producing fluids from the formation.