baber/WOPTO huggingface dataset:
Patent EA-013119-B1 (EA)
Title: Salt of proline derivate, solvate thereof and production method thereof
Inventor: YOSHIDA TOMIHIRO
IPC: A61K31/496
Filed: 2006-02-17
Abstract: Disclosed is a compound of 3-{(2S,4S)-4-[4-(3-methyl-1-phenyl- 1H-pyrazole-5-yl)piperazine-1-yl]pyrrolidine-2-ylcarbonyl} thiazolidine (compound I) which is useful as a dipeptidyl peptidase IV inhibitor. This compound has excellent characteristics in stability and moisture absorption, while having a reproducible crystal structure. Also disclosed is a method for producing such a compound.
Patent EA-012443-B1 (EA)
Title: Pharmaceutical composition comprising a 1-(3-chlorophenyl)-3-alkylpiperazine for treating appetite disorder
Inventor: GARRONE BEATRICE
IPC: A61P3/04
Filed: 2006-06-02
Abstract: Use of a 1-(3-chlorophenyl)-3-alkylpiperazine of formula (I), in racemic (R, S) form or in the form of the (S) enantiomer, in which R is a linear or branched alkyl group having from 1 to 3 carbon atoms, or of an addition salt thereof with a pharmaceutically acceptable organic or inorganic acid, for treating appetite disorder. A pharmaceutical composition that comprises a therapeutically effective amount of a 1-(3-chlorophenyl)-3-alkylpiperazine of formula (I) as previously defined or of an addition salt thereof with a pharmaceutically acceptable organic or inorganic acid, and at least one pharmaceutically acceptable excipient.
Patent EA-015149-B1 (EA)
Title: Methods of fracturing formations using quaternary amine salts as viscosifiers
Inventor: HUTCHINS RICHARD D
IPC: C09K8/68
Filed: 2006-10-19
Abstract: Disclosed are methods of treating subterranean formations, particularly, treatment methods including preparation of an aqueous treatment fluid composition composed of a carboxy modified polymer, a crosslinking agent, and a viscosifying quaternary amine salt, and subsequently introducing the composition into a the formation to treat. The treatment method is particularly useful for fracturing a subterranean formation. The polymer and crosslinker may be premixed and injected into a wellbore, then mixed therein with the quaternary amine salt to treat the formation. In another aspect, the polymer, crosslinker, and quaternary amine salt are mixed, injected into a wellbore, and introduced in the formation for treatment.
Patent EA-014895-B1 (EA)
Title: Drive of propulsion device
Inventor: GOYTEMIROV RAMZAN USMANOVICH
IPC: F16H31/00
Filed: 2006-09-13
Abstract: The invention may be employed as a wheel-engine of a vehicle, comprising functions of internal combustion engine and of non-gradual speed gear-box and directed to the simplification of the construction, lessening of dimensions and depletion of fuel. The drive of propulsion device, comprising a propulsion device in the form of a rim, mounted with possibility of rotation, a piston engine, placed inside of it, with a block of cylinders having at least one piston, installed in it with possibility of reciprocating movement in the direction radial to the axis of rotation of the rim, a mechanism for transmission of the movement of the piston into a rotating movement of the rim, comprising a connecting rod hinged with each piston and having a pressure roller on the other end, placed in a raceway, having oval or any other configuration symmetric about the axis of rotation of the rim, made on a synchronizing disk installed with possibility of concentric rotation on the axis of rotation of the rim. The mechanism for transmission of the movement of the piston into a rotating movement of the rim is equipped with eccentric driving axes, mounted on each connecting rod with possibility of swinging and interaction with grooves, made aslant towards the radial about the center of rotation of the rim line on the block of cylinders and at least one overrunning clutch mounted on the swing lever with possibility of interaction with the rim. The drive is equipped with a device for controlling the frequency of rotation of the rim, as a mechanism for misalignment of the lever or the turn disk and change of a slope of the groove, made on them, towards the line radial about the center of rotation of the rim. The drive is supplied with a device for controllable or adaptive change of compression ratio in a piston internal combustion engine, comprising supporting levers hinged with the connecting rods and with their other ends also hinged with a tie-rod mechanism mounted on the block of cylinders. The overrunning clutch is installed between the rim and the synchronizing disk.
Patent EA-021239-B1 (EA)
Title: A process for a preparation of marbofloxacin and intermediate thereof
Inventor: ZUPET ROK
IPC: C07D215/58
Filed: 2010-11-19
Abstract: The present invention describes a novel process for the preparation of marbofloxacin and intermediate thereof comprising reaction of ammonium hydroxide of formula (III), NRRRR, wherein R, R, Rand Rare independently selected from the group of H, alkyl, alkylaryl, aryl and/or heteroaryl, with compound of formula (II), wherein R is selected from H, alkyl, arylalkyl, alkali metal cation, NHcation, NRRRRcation; X is halogen, such as chloro, bromo, fluoro, piperazinyl, which may be substituted or unsubstituted, and R' is selected from H, formyl or COO-alkyl.
Patent EA-027805-B1 (EA)
Title: Process and plant for separating heavy metals from phosphoric starting material
Inventor: LOHRBERG DIRK
IPC: C22B7/00
Filed: 2013-06-21
Abstract: A process for separating heavy metals from phosphoric starting material comprising the following steps: (i) heating the starting material to a temperature between 700 and 1.100°C in a first reactor and withdrawing combustion gas, and (ii) transferring the heated starting material to a second reactor, adding chlorides of alkaline and earth alkaline metals and withdrawing process gas.
Patent EA-034779-B1 (EA)
Title: Method and system for upgrading heavy hydrocarbons using catalytic hydrocracking and thermal coking
Inventor: HARRIS EVERETTE
IPC: C10G47/06
Filed: 2013-07-26
Abstract: Methods and systems for hydroprocessing heavy oil feedstocks to form an upgraded material involve the use of a well-dispersed metal sulfide catalyst (e.g., colloidal or molecular catalyst) dispersed within a heavy oil feedstock, a pre-coking hydrocracking reactor, a separator, and a coking reactor. The metal sulfide catalyst promotes upgrading reactions that reduce the quantity of asphaltenes or other coke forming precursors in the feedstock, increase hydrogen to carbon ratio in the upgraded material, and decrease boiling points of hydrocarbons in the upgraded material. The methods and systems can be used to upgrade vacuum tower bottoms and other low grade heavy oil feedstocks. The result is one or more of increased conversion level and yield, improved quality of upgraded hydrocarbons, reduced coke formation, reduced equipment fouling, processing of a wider range of lower quality feedstocks, and more efficient use of supported catalyst if used in combination with the metal sulfide catalyst, as compared to a conventional hydrocracking process or a conventional thermal coking process.
Patent EA-030602-B1 (EA)
Title: Fluid conduit
Inventor: JONES MARTIN PETER WILLIAM
IPC: G01R33/12
Filed: 2012-05-10
Abstract: A fluid conduit comprises a wall defining a fluid flow path and comprising a composite material formed of at least a matrix and one or more reinforcing elements embedded within the matrix; and a component at least partially embedded within the wall and configured to transmit energy to and/or receive energy from the fluid flow path. A region of the wall between said component and the fluid flow path is substantially devoid of reinforcing elements to define a transmission path for energy between the fluid flow path and this component. The fluid conduit may be configured for sensing a property of a fluid present in or flowing through the fluid flow path or for use in sensing a property of a fluid present in or flowing through the fluid flow path.
Patent EA-039407-B1 (EA)
Title: Encoderless motor with improved granularity and methods of use thereof
Inventor: PHAN TIEN
Filed: 2016-07-22
Abstract: A DC electric motor having a stator mounted to a substrate, the stator having a coil assembly having a magnetic core, a rotor mounted to the stator with permanent magnets distributed radially about the rotor, the permanent magnets extending beyond the magnetic core, and sensors mounted to the substrate adjacent the permanent magnets. During operation of the motor passage of the permanent magnets over the sensors produces a substantially sinusoidal signal of varying voltage substantially without noise and/or saturation, allowing an angular position of the rotor relative the substrate to be determined from linear portions of the sinusoidal signal without requiring use of an encoder or position sensors and without requiring noise-reduction or filtering of the signal.
Patent EA-038823-B1 (EA)
Title: System and method for correction of seismic receiver clock drift
Inventor: ETGEN JOHN THEODORE
Filed: 2016-12-05
Abstract: According to one embodiment, there is provided a method of correcting recorded seismic data where each receiver clock is potentially inaccurate. Since the seismic wave field is not random, and contains coherent events that are recorded by all receivers in a local area, it is possible to estimate the differences in the time reference by comparing the recordings of different receivers in a local area. With no external time reference, time signal, or pilot trace, an entire seismic data itself can be used to determine how each receiver's clock is drifting from true time.
Patent EA-039101-B1 (EA)
Title: Encapsulation of ultra-stable insulin analogues with polymer melts
Inventor: WEISS MICHAEL
Filed: 2016-12-23
Abstract: An insulin composition comprises an insulin analogue and polymer blend. The insulin analogue contains cysteine substitutions at positions B4 and A10 (to form cystine B4-A10), and one or more additional substitutions selected from the group consisting of a connecting domain of 5-11 amino acids between A and B domains of the insulin analogue; a non-beta-branched amino-acid substitution at a position corresponding to position A8 of wild type insulin; a non-beta-branched acidic or polar side chain at a position corresponding to position A14 of wild type insulin; a halogenic modification of the aromatic ring of Phe at a position corresponding to position B24 of wild type insulin at the ortho position of the aromatic side chain; and substitution of lysine at a position corresponding to position B29 of wild type insulin by arginine, glutamic acid, alanine, valine, isoluecine, leucine, amino-propionic acid, amino-butryic acid or norleucine. The insulin analogue is compatible with a process of manufacture that includes one or more steps within the temperature range 90-120°C. The encapsulated insulin analogue may optionally contain free PEG or be PEGylated. The insulin analogue-encapsulated polymer blend may be cast as a microneedle patch for topical administration or as micropellets for subcutaneous injection.
Patent EA-035260-B1 (EA)
Title: Multilayer substrate for electrochromic light control element and method for producing electrochromic light control element
Inventor: AOSHIMA YUKI
IPC: G02F1/15
Filed: 2017-02-07
Abstract: A multilayer substrate for electrochromic light control elements, which comprises a glass substrate and a transparent conductive film, and wherein: the glass substrate contains silicon oxide, aluminum oxide, boron oxide, alkaline earth metal oxides and alkali metal oxides in a total amount of 90 mol% or more, while containing the alkali metal oxides in a total amount of 12 mol% or less; the transparent conductive film sequentially comprises, from the glass substrate side in the following order, an indium oxide film containing tin and a tin oxide film containing one or more elements selected from among tantalum, antimony and fluorine; the indium oxide film is formed directly on the glass substrate and has a refractive index lower than 0.4 and an extinction coefficient higher than 0.4; and the tin oxide film has a film thickness of more than 35 nm but not more than 150 nm.
Patent EA-039144-B1 (EA)
Title: New heteroaryl amide derivatives as selective inhibitors of histone deacetylases 1 and/or 2 (hdac1-2)
Inventor: CASTRO PALOMINO LARIA JULIO
Filed: 2018-07-09
Abstract: The invention relates to novel heteroaryl amide derivatives of formula (I)as selective inhibitors of histone deacetylase 1 and/or 2 (hdac1-2), to methods for the production of same, to pharmaceutical compositions comprising these compounds, and to the use of said compounds for the production of a medicament for the treatment of pathological conditions or diseases that can be improved by means of the inhibition of the activity of histone deacetylase class I, particularly HDAC1 and HDAC2, such as cancer, neurodegenerative diseases, infectious diseases, inflammatory diseases, heart failure and cardiac hypertrophy, diabetes, polycystic kidney disease, sickle cell disease and -thalassemia disease, and to methods for the treatment of the diseases mentioned above.
Patent ES-2183705-B1 (ES)
Title: Sistema para la recuperacion de la sal contaminada para usos industriales.
Inventor: GIMENO CERDAN MIGUEL
IPC: C01D3/20
Filed: 2001-02-08
Granted: 2004-01-16
Abstract: Sistema para la recuperación de la sal contaminada para usos industriales, ideado para poder reciclar la sal procedente de los secaderos de carnes y pescados, caracterizado porque la sal contaminada de conservantes y bacterias, es introducida en un horno de fundición de metales, preferentemente de tipo rotativo en donde alcanza una temperatura de entre 800 y 2.200ºC, pasando a estado líquido, para una vez cumplida su fase de colaboración en la fusión del metal, como por ejemplo del aluminio, ser extraída dicha sal en estado líquido libre de productos químicos y bacterias. Una vez solidificada la sal, puede ser utilizada en diversos usos industriales, para carreteras, o bien ser almacenada en depósitos controlados.
Patent ES-2180417-B1 (ES)
Title: Nueva proteina sobreexpresada en cancer de prostata.
Inventor: THOMSON OKATSU TIMOTHY
IPC: C12N15/12
Filed: 2001-03-14
Granted: 2004-05-16
Abstract: Nueva proteína sobreexpresada en cáncer de próstata. Un nuevo gen y proteína sobreexpresado en cáncer de próstata ha sido identificado y secuenciado. En la presente invención se demuestra que se sobreexpresa en adenocarcinoma de próstata mediante la técnica RT-PCR y western-blot. La expresión de esta proteína está correlacionada con la proliferación de tumores. Han sido generados anticuerpos específicos que detectan específicamente la proteína tanto en líneas celulares como en tejidos humanos normales y tumorales usando métodos inmunológicos. Empleando estos anticuerpos, demostramos que la proteína se sobreexpresa en la mayoría de los adenocarcinomas de próstata humanos, por lo que la detección de este transcrito y proteína constituye un nuevo marcador de este tipo de tumores, con potencial utilidad en su diagnóstico. Esta proteína es además una proteína diana la identificación de compuestos para terapias antitumorales.
Patent ES-2178613-B1 (ES)
Title: Composicion de un hidrocarburo ecologico.
Inventor: MARTINEZ DIEZ ABEL
IPC: C10L1/30
Filed: 2001-06-13
Granted: 2004-08-01
Abstract: Composición de un hidrocarburo ecológico, que comprende utilizar: aceite de soja 97% en peso y etanoles 3% en peso. Los etanoles se componen de la levadura saccharomyces spp en un 10% en peso y de las siguientes plantas: Suaeda vera 60% en peso y Atriplex halimus 30% en peso.
Patent ES-2193843-B1 (ES)
Title: Procedimiento para la inactivacion reversible por calor, e in vivo, de proteinas con actividad biologica.
Inventor: ROJAS GONZALEZ ANA ISABEL
IPC: C12N15/82
Filed: 2001-07-06
Granted: 2005-03-01
Abstract: Procedimiento para la inactivación reversible por calor, e in vivo, de proteínas con actividad biológica. El procedimiento permitiría que una proteína a la que se le añaden nuevos aminoácidos, pueda perder de forma transitoria su actividad biológica: enzimática, reguladora, o cualquier otro tipo de función que esta posea. Los aminoácidos añadidos proceden de HSPs (Heat Shock Proteins). La inactivación ocurre tras un tratamiento breve con calor (choque térmico), tras el cual la actividad de la proteína modificada se recupera con un cierto retraso (entre las 3 y 24 horas después del tratamiento). Esta herramienta podría utilizarse, por ejemplo, para el diseño de nuevos sistemas de expresión inducible de genes en plantas transgénicas.
Patent ES-2193860-B1 (ES)
Title: Procedimiento para el cultivo de dunaliella salina rica en b-caroteno en fotobiorreactor tubular cerrado a la intemperie.
Inventor: GARCIA GONZALEZ MERCEDES
IPC: C12N1/12
Filed: 2001-12-17
Granted: 2005-03-01
Abstract: Procedimiento para el cultivo de Dunaliella salina rica en b- caroteno en fotobiorreactor tubular cerrado a la intemperie. El objeto de la presente invención es un procedimiento para el cultivo a la intemperie de la microalga Dunaliella salina rica en b-caroteno que utiliza un fotobiorreactor tubular cerrado como alternativa a los sistemas abiertos. Mediante el procedimiento de la invención se alcanzan elevados valores de productividad tanto de biomasa como de carotenoides. Este sistema posibilita un control estricto del proceso de cultivo y, consecuentemente, permite asegurar la constancia de composición y calidad del producto.
Patent ES-2245200-B1 (ES)
Title: Colchon de muelles a base de material espumado.
Inventor: TORRES CERVERA MANUEL
IPC: A47C27/15
Filed: 2003-11-25
Granted: 2007-04-01
Abstract: Colchón de muelles a base de material espumado. Se describe un colchón de muelles en el que se utilizan una multiplicidad de muelles elásticos, distribuidos espacialmente según un patrón predeterminado, con configuraciones ampliamente variables, obtenidos por conformación mediante operaciones de corte y vaciado de una plancha inicial de material espumado de espesor adecuado. La configuración adoptada determina en los elementos de muelle porciones entrantes que afectan a uno o más de sus lados, de magnitud y profundidad variables, y porciones sobresalientes desde uno o más de sus lados, con espesores y alcances de proyección asimismo variables. Los muelles que forman el colchón son integrales por su extremo inferior con una porción laminar continua restante de la plancha original, y según una versión alternativa, pueden estar unidos por su extremo opuesto a una plancha laminar continua o discontinua, a la que se vinculan mediante alguna operación de pegado o similar.
Patent ES-2244312-B1 (ES)
Inventor: KLEMM JOCHEN
IPC: A47J37/12
Filed: 2004-02-05
Granted: 2007-02-16
Abstract: The deep fryer has a base, into which the frying basket fits, and a lid (3). This has a cut-out (8a) near the front, into which the handle (7) of the basket fits for storage.
Patent ES-2244315-B1 (ES)
Title: Aparato de interpretacion para libro de audio y tarjeta de voz, y metodo de control del mismo.
Inventor: KIM KYONG HO
IPC: G09B19/06
Filed: 2004-02-19
Granted: 2006-10-01
Abstract: Aparato de interpretación para libro de audio y tarjeta de voz, y método de control del mismo. El aparato de interpretación para tarjeta de voz y libro de audio comprende una unidad detectora de tarjeta de voz, una unidad detectora de páginas de unidad de audio, una unidad de transferencia de tarjeta de voz, una memoria que comprende una unidad de almacenamiento de información de tarjeta de voz y una unidad de almacenamiento de información de un libro de audio, una unidad de proceso de información digital, un altavoz, y una MCU para controlar el funcionamiento de todos los componentes. Al prever un método de control cuando la tarjeta de voz es insertada durante la salida del libro de audio, los datos restantes del libro de audio pueden ser emitidos después de que se ha realizado una modalidad de interpretación de tarjeta de voz, sin errores por mala manipulación.
Patent ES-2324573-B1 (ES)
Title: Medios de elevacion y soporte para base de colchon.
Inventor: BARRANCO BARRANCO GREGORIO
IPC: A47C19/04
Filed: 2006-11-27
Granted: 2010-05-26
Abstract: Medios de elevación y soporte para base de
colchón, conformado por una  base a la que hay fijados sendos
largueros superiores, contando con una  estructura inferior
conformada por unos largueros inferiores unidos por  unos
travesaños, siendo elevable la base del colchón respecto de la
estructura  inferior mediante dos cuadriláteros articulados
conformados por los largueros  inferiores y superiores y por unos
brazos articulados en sus extremos en  los largueros, estando al
menos uno de los brazos articulados de cada uno  de los
cuadriláteros asociados a un cilindro hidráulico, donde de la parte 
inferior de la base emergen unas patas de soporte donde reposa la
base  del colchón cuando no está elevada, mientras que la estructura
inferior  es soportada por unas ruedas unidas a los largueros
inferiores, de manera  que cuando la base del colchón esta sobre
elevada, todo el conjunto reposa  sobre las ruedas anteriores,
siendo todo el conjunto fácilmente desplazable.
Patent ES-2311390-B1 (ES)
Title: Disposicion absorbedora de humedad para calzados, tejidos y cueros.
Inventor: CANTO CANO JOSE
IPC: A41B9/00
Filed: 2006-06-19
Granted: 2009-12-03
Abstract: Disposición absorbedora de humedad para
calzados, tejidos y cueros. 
     Se establecen, en aquellas zonas del calzado o
confecciones sobre las que se prevé  un problema de sudoración,
pequeños receptáculos (4) ocupados por gel de sílice (5) 
configurado en forma de estructura cristalina, presentando
canalizaciones que no  restringen el flujo de aire a su través.
Adicionalmente, los receptáculos (4) citados  pueden realizarse de
tal manera que su revestimiento interno (2), o forro, sea de un 
material que permita el paso del sudor.
Patent ES-2302654-B1 (ES)
Inventor: GARCIA LOPEZ DE LACALLE FELIPE
IPC: E04B1/10
Filed: 2007-12-19
Granted: 2009-08-24
Abstract: The construction system has one or multiple plants, base panel, which has vertical plank. The joint between horizontal panels are taken out from the bars by stretching machine. The joint and overlapping between vertical panels are carried out by elements that has hidden joint in the panels.
Patent ES-2316305-B1 (ES)
Title: Sistema de fijacion para fachada ventilada.
Inventor: PASTRANA SANCHEZ ANGEL
IPC: E04F13/08
Filed: 2005-06-13
Granted: 2010-01-22
Abstract: Sistema de fijación para fachada ventilada. 
     La presente invención tiene por objeto un
sistema de fijación para fachada  ventilada que permite fijar las
placas que componen la fachada ventilada  de manera sencilla y sin
necesidad de tornillos o remaches, donde además,  debido a su
especial configuración, se asegura la equidistancia en altura  entre
una placa y la siguiente mediante la unión de una pieza de sujeción 
y una pieza de apoyo colocadas entre dos placas ya que la pieza de
sujeción  apoya en la placa inferior y presenta medios para acoplar
la pieza de apoyo  donde se introduce y apoya la placa inmediata
superior debido a los huecos  que presentan las placas.
Patent ES-2350994-B1 (ES)
Title: Placa frontal para paneles publicitarios de campos deportivos
Inventor: CASTRO ABIA FELIX
IPC: G09F9/33
Filed: 2009-07-08
Granted: 2012-01-10
Abstract: Placa frontal para paneles publicitarios de campos deportivos, para paneles formados con leds mediante los que se forman exposiciones luminosas, componiéndose la placa por asociación de plaquetas (2) de material plástico flexible, las cuales poseen una distribución de orificios (5) en filas que se corresponden con la distribución de los leds del panel publicitario de aplicación, saliendo por encima de las filas de orificios (5) unas viseras (8) del mismo material plástico flexible que la plaqueta, mientras que paralelamente a esas filas de orificios (5) se hallan definidas unas zonas estriadas (9).