baber/WOPTO huggingface dataset:
Patent FI-934501-A0 (FI)
Inventor: WENLING KAO
IPC: A61K31/495
Filed: 1993-10-12
Abstract: The invention concerns a compound of the structure <CHEM>  wherein R<1> and R<2> are each, independently, hydrogen,  -CONH-Ä(CR<3>R<4>)m(-A-(CR<5>R<6>)n)pÜq-B; <CHEM> R<3>, R<4>, R<5>, R<6>, R<9> and R<10> are each defined substitutents, and R<3-6> may each also represent hydrogen, B is alkenyl of 2-7 carbon atoms, alkynyl of 2-7 carbon atoms, hydroxyalkyl of 1-6 carbon atoms, alkylthioalkyl of 2-12 carbon atoms, alkylaminoalkyl of 2-12 carbon atoms, dialkylaminoalkyl of 3-12 carbon atoms, -OR<7>, -SR<7>, -CN, -COR<7>, -CONHR<7>, -OSO3R<7>, -NR<7>R<8>, -NHCOR<7>, -NHSO2R<7>, or Ar; A is -CH2-, -NR<7>-, -O-, -S-, -SO-, -PR<7>-, -NHCO-, -NHSO- or -P(O)(R<7>)-; Ar is naphthyl, pyridyl, quinolyl, isoquinolyl, quinoxalyl, thienyl, thionaphthyl, furyl, benzofuryl, benzodioxyl, benzoxazolyl, benzoisoxazolyl, indolyl, thiazolyl, isoxazolyl, pyrimidinyl, pyrazinyl, imidazolyl, benzopyranyl, benzÄbÜthiophenolyl, benzimidazolyl, benzthiazolyl, benzodioxolyl, piperidinyl, morpholinyl, piperazinyl, tetrahydrofuranyl, or pyrrolidinyl; wherein the Ar group may be optionally mono-, di-, or tri- substituted with a group selected from alkyl of 1-6 carbon atoms, arylalkyl of 7-10 carbon atoms, alkoxy of 1-6 carbon atoms, cyano, halo, hydroxy, nitro, carbalkoxy of 2-7 carbon atoms, trifluoromethyl, amino, dialkylamino of 1-6 carbon atoms per alkyl group, dialkylaminoalkyl of 3-12 carbon atoms, hydroxyalkyl of 1-6 carbon atoms, alkoxyalkyl of 2-12 carbon atoms, alkylthio of 1-6 carbon atoms, -SO3H -PO3H, and -CO2H; PO3H, and -CO2H; <CHEM> is a nitrogen containing heterocycle that may be saturated, unsaturated, or partially unsaturated, and may be optionally mono-, di-, or tri- substituted with a defined substituent, with the proviso that R<1> and R<2> are not both hydrogen;  m=0-6; n=0-6; p=0-1; q=0-1; or a pharmaceutically acceptable salt thereof which is useful as an immunosuppressive, antiinflammatory, antifungal, antiproliferative, and antitumor agent.
Patent FI-935636-A0 (FI)
Inventor: HIMMRICH JOHANNES
IPC: C09K3/18
Filed: 1993-12-15
Abstract: The alkaline earth metal/sodium acetate according to the invention comprises     from 18 to 22 % by weight of calcium (Ca<++>),   from 0 to 1 % by weight of magnesium (Mg<++>),   from 4 to 7 % by weight of sodium (Na<+>),   from 66 to 75 % by weight of acetate (CH3COO<->),   from 0 to 7 % by weight of water, and   from 0 to 2 % by weight of water-insoluble components.   It is prepared by reacting a calcium oxide containing at least 85 % of CaO with acetic acid and sodium hydroxide solution and granulating the reaction product to give particles of from 0.5 to 5 mm. The alkaline earth metal/sodium acetate according to the invention can be used as an environmentally friendly and low-corrosion deicing agent.
Patent FI-941038-A0 (FI)
Inventor: SELB MICHAEL
IPC: E21B1/00
Filed: 1994-03-04
Abstract: The tool for insertion into a tool chuck for handtools which are used for chiselling, rotary drilling and/or rotary percussion drilling has a clamping shank (A) with two axially closed locking grooves (1), two rotary driving grooves (2) which are axially open towards the free end of the clamping shank (A), and two rotary driving faces (3). <IMAGE>
Patent FI-955830-A0 (FI)
Inventor: DRIVON GILLES
IPC: C07C69/63
Filed: 1995-12-04
Abstract: Prepn. of alkyl halo-difluoroacetates of formula CF2X-CO-OR (I), comprises reaction of 1,1-difluorotetrahaloethane of formula CF2XCY2Z (II) with an alcohol of formula ROH (III), in the presence of oxygen and a free radical generator. X = F, Cl, Br or I; R = 1-10C aliphatic hydrocarbyl; Y, Z = Cl, Br or I.
Patent FI-972572-A0 (FI)
Inventor: JUENEMANN ALFONS
IPC: F04C19/00
Filed: 1997-06-17
Abstract: PCT No. PCT/EP95/05093 Sec. 371 Date Jun. 17, 1997 Sec. 102(e) Date Jun. 17, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/20346 PCT Pub. Date Apr. 4, 1996A liquid ring gas pump has a pressure space and a pressure pipe connected to the top of the pressure space. A tubular silencer is suspended from the pressure pipe and extends into the pressure space. The silencers are detachable and may be inserted through the pressure pipe. The detachable silencers are retained by an elastic ring retained in a ring-shaped groove of the pressure pipe.
Patent FI-973834-A0 (FI)
Inventor: DE ZEN VITTORIO
IPC: E05F15/665
Filed: 1997-09-29
Abstract: PCT No. PCT/CA96/00218 Sec. 371 Date Oct. 15, 1997 Sec. 102(e) Date Oct. 15, 1997 PCT Filed Apr. 11, 1996 PCT Pub. No. WO96/33333 PCT Pub. Date Oct. 24, 1996Hinge member extrusions for use in forming a hinge connection, each member having a front wall and a rear wall and presenting at one edge a generally C-shaped socket formation, the socket formation having a first part circular edge wall segment extending arcuately inwardly of the edge of the front wall to adjacent the rear wall and being connected thereto, and a second part circular arm segment connected to an end of the first part circular wall segment by a web extending inwardly of the first part circular wall segment, the first and second part circular segments having a common center with the radius of the inner surface of the first part circular wall segment being slightly greater than the radius of the outer surface of the second part circular arm segment. Two such hinge members are required in forming a hinge formation to receive a pintle, one of the hinge members has its part circular arm segment connected to its part circular wall segment at the end adjacent the rear wall. The other has its part circular arm section connected to its part circular wall segment at the end at the edge of the front wall.
Patent FI-981038-A0 (FI)
Inventor: HURME HARRI
IPC: H04Q1/446
Filed: 1998-05-11
Abstract: An electric device is intended for detecting the presence of a signal having a certain frequency (401) in a line connection (301). It comprises at least three energy-storing components (302, 303, 304, 305, 501, 502, 503, 504) connected in parallel to the line connection, switching means (306) for making a connection selectively from each energy-storing components to a certain reference, means (CLK1, CLK2) for controlling the switching means at a predetermined frequency, and means (307, 308, 309) for measuring a certain quantity comparable to the energy stored from each energy-storing component.
Patent AP-9700946-A0 (AP)
Title: A traffic control system, use of it, and a method of controlling the movement of a mobile unit.
Inventor: PEDERSEN HEINE EWI
IPC: G08G1/09
Filed: 1995-09-25
Abstract: A traffic control system for mobile units comprises a plurality of stationary, passive units having electronic store capacity and transmit and receive facilities. The store of the passive units contains an information code which is unique to the unit and is related to the position of the unit concerned. A mobile unit has a computer with associated store capacity and transmit and receive facilities. When interrogated by a mobile unit, the stationary units supply their information code, enabling the mobile unit to calculate its position. The store of the stationery units, in addition to the information codes of said units, contains stored traffic messages which are supplied together with the information code upon interrogation from the mobile unit. The movement from the mobile unit can be adjusted according to the traffic information received.
Patent IL-60893-A0 (IL)
Title: S-alkyl phosphonodithioic halides and their preparation
IPC: C07F9/42
Filed: 1980-08-21
Abstract: Compounds useful as intermediates for insecticides and nematocides having the formula <CHEM> in which R is alkyl of 1 to 6 carbon atoms; R1 is alkyl of 4 to 8 carbon atoms which is alpha branhced; and X is halogen are disclosed as well as their preparation by direct reaction of an alkylphosphonothioic dihalide with an alipha branched alkyl thiol.
Patent IL-68778-A0 (IL)
Title: Indolizine derivatives,their preparation and pharmaceutical compositions containing them
IPC: C07D209/44
Filed: 1983-05-25
Abstract: Indolizine derivatives corresponding to the general formula: <IMAGE>   and the pharmaceutically acceptable acid addition salts thereof, wherein: R represents a straight- or branched-chain alkyl radical having from 1 to 4 carbon atoms or a phenyl radical, R1 represents a straight- or branched-chain alkyl radical having from 1 to 6 carbon atoms, X1 represents hydrogen, chlorine, bromine, methyl or methoxy, A represents a radical of the formula:   <IMAGE>  in which X2 represents hydrogen, chlorine, bromine, methyl or methoxy, n represents 1 or 2, a process for preparing said derivatives, pharmaceutical or veterinary compositions containing at least one of said derivatives and a method of treating pathological syndromes of the heart by administration of at least one of said derivatives to a subject in need of such treatment.
Patent IL-75568-A0 (IL)
Title: 5-amino-4-heterocyclyl-1-phenylpyrazoles,their preparation and their use as herbicides and plant growth regulators
IPC: A01N43/56
Filed: 1985-06-19
Abstract: 5-Amino-4-heterocyclyl-1-phenylpyrazoles of the formula   <IMAGE> in which R1 represents hydrogen or alkyl, R2 represents hydrogen or a radical   <IMAGE>  R3 represents hydrogen,    <IMAGE>  alkyl, alkenyl or alkinyl, R4, R5, R6, R7 and R8 independently of one another represent hydrogen, cyano, nitro, halogen, alkyl, alkoxy, alkoxycarbonyl, halogenoalkyl, halogenoalkoxy or a radical -S(O)n-R10, R9 represents hydrogen, alkyl, alkenyl, alkinyl, halogenoalkyl, alkoxyalkyl, alkylthioalkyl, optionally substituted cycloalkyl, optionally substituted aryl, alkoxy, alkylthio, optionally substituted aryloxy or aryloxyalkyl, optionally substituted arylthio, alkylamino, dialkylamino or optionally substituted arylamino, R10 represents alkyl, halogenoalkyl, amino, alkylamino or dialkylamino, X represents oxygen or sulphur, n represents the number 0, 1 or 2 and Het represents a saturated or unsaturated optionally substituted heterocyclic radical, exhibit herbicidal and plant growth-regulating activity.
Patent IL-76023-A0 (IL)
Title: Stable salts of s-adenosyl-l-methionine(sam)with polyanions
IPC: A61K31/7064
Filed: 1985-08-06
Abstract: Stable salts of S-adenosyl-L-methionine with water-soluble polyanions, such as polyphosphates, polyvinylsul- fonates -sulfates or -phosphates, polyacrylates, polystyrene sulfonates, are described.The salts according to the invention, prepared by precipitation from aqueous solutions of pH not exceeding 3.5, possess peculiar stability, solubility, nonhygroscopicity and are valuable for use as active constituents in pharmaceutical compositions.
Patent IL-83334-A0 (IL)
Title: Process for the preparation of esters of 4-(2,3-epoxypropoxy)phenylacetic and 4-(2-hydroxy-3-isopropylamino-propoxy)phenylacetic acid and/or atenolol in stereospecific form
IPC: C07C233/00
Filed: 1987-07-27
Abstract: S-(-)-atenolol (4-(2-hydroxy-3-isopropylaminopropoxy)phenyl acetamide) is obtained by a process including the step of stereo-specific epoxidation by an ester of 4-allyloxyphenylacetic acid using a micro-organism capable of stereo-selective epoxidation, e.g. Pseudomonas oleovorans, to produce the corresponding ester of 4-(2,3-epoxypropoxy)phenylacetic acid which is predominantly in S configuration. Pseudomonas oleovorans ATCC 29347 produces at least about 90% of the epoxypropoxy compound in S configuration. The resulting epoxypropoxy compound can be converted into atenolol, maintaining the high proportion of S configuration, by reacting the epoxypropoxy compound with isopropylamine and converting the ester group to an amide group by reaction with ammonia.
Patent IL-86395-A0 (IL)
Title: Pharmaceutical compositions containing flunarizine
IPC: A61K47/48
Filed: 1988-05-16
Abstract: Compostions containing flunarizine as active ingredient and as carrier an appropriate surfactant, said surfactant preferably being a polyethoxylated fatty acid or alcohol or a polyethoxylated oil or fat (glyceride) and more in particular said polyethoxylated fatty acid, alcohol, oil or fat contains 5 to 100 and preferably 20 to 60 ethoxy units, and if desired, other adjuvants.
Patent IL-96618-A0 (IL)
Title: Pharmaceutical compositions containing fluoroquinolone derivatives
IPC: A61K31/495
Filed: 1990-12-10
Abstract: Application of fluoroqinolone derivatives of general formula (I) is taught, in which R1 is alkyl (1 to 4C), fluoroethyl, cyclopropyl or difluorophenyl, R2,R3 and R4 are identical or different and represent hydrogen atoms or methyl radicals, X is N or a group =CR6 in which R6 is a hydrogen or fluorine atom, or alternatively R6 with R1 and the atoms to which they are attached forms a six-membered heterocycle substituted with a methyl radical and containing an oxygen atom, and R5 is a hydrogen atom, or represents an amino radical if R6 is a fluorine atom, as well as of their salts, for obtaining a medicinal product intended for the preventive and/or curative treatment of pneumocystosis.   <IMAGE> (I)
Patent IL-96723-A0 (IL)
Title: Novel platelet-derived growth factor b chain analogs and method for homogeneous production thereof
IPC: A61P43/00
Filed: 1990-12-19
Abstract: Novel platelet-derived growth factor (PDGF) analogs are provided in accordance with the present invention. Also provided is a method for the production of homogeneous quantities of these novel analogs. The novel analogs of the present invention, when refolded, have substantially the same biological activity as naturally occurring PDGF B109. The method of the present invention employs the use of a stop codon on the c-sis gene, or other coding sequence for a precursor protein of PDGF B109, or analogs thereof, at a position corresponding to a location from about amino acid 111 to about amino acid 160. The method of the present invention results in the production of relatively large homogeneous quantities of recombinant PDGF B analogs from high expression host cells, such as E. coli.
Patent FI-20010115-A0 (FI)
Inventor: WATANABE WIWIK
IPC: A61K31/192
Filed: 2001-01-18
Abstract: The invention relates to free nano-sized particles of active agents e.g. therapeutic, cosmetic or diagnostic agents, and to a method for the preparation of such particles. The method comprises providing a liquid feed stock comprising an active agent or combination of two or more active agents, atomising the liquid feed stock, suspending the droplets in a carrier gas, and passing the carrier gas and droplets through a heated tube flow reactor under predetermined residence time and temperature history, and collecting the particles produced. Nano-sized crystalline spherical uncharged particles with narrow aerodynamic particle size distribution and rough surfaces, are obtained. The particles show improved dissolution rate in-vitro and bioavailability in-vivo, dispersibility and stability.
Patent FI-20030757-A0 (FI)
Inventor: NAQVI SHAMIM
IPC: H04W92/12
Filed: 2003-05-21
Abstract: A proxy switch, communication methods, and communication logic for use in a mobile network are described. A proxy switch is deployed between a base station subsystem and a mobile station center. It receives signaling messages and either retransmits them, blocks them, converts them, or siphons them to an alternative network. Besides providing an ability to offload offload mobile traffic it provides a platform for new communication services. The proxy switch includes signaling message handling logic that receives signaling messages from the MSC and BS in accordance with a mobile signaling protocol. State logic maintains state information of call sessions and mobile stations (MSs) used within the mobile communications network. Message interception logic detects whether a signaling message from an MSC is a new call originating message and if an MS addressed in such a new call originating message is involved in a call. The message interception logic also prevents the new call originating message from being forwarded to the BS servicing the addressed MS. Message conversion logic converts the new call originating message to a feature notification message, and message transmission logic issues the feature notification message to the BS servicing the addressed MS.
Patent FI-20031644-A0 (FI)
Inventor: LIPPONEN PENTTI
IPC: B64F1/06
Filed: 2003-11-12
Abstract: A method of launching a catapult, a catapult and a locking device for a catapult. The catapult comprises a carriage for fastening an aircraft. The carriage can be provided with a high acceleration by directing a launching force generated by a launching device thereto. The carriage can be held at a launching position by means of the locking device. The catapult further comprises a takeoff damper that generates a damping force having a direction opposite relative to the launching force. Accordingly, the takeoff damper restricts the acceleration of the carriage at the initial launching moments.
Patent FI-20075793-A0 (FI)
Inventor: SILVONEN AULIS
IPC: F02F/
Filed: 2007-11-09
Abstract: The invention relates to a prechamber arrangement to be fitted into the cylinder head (2) of a combustion engine (1), comprising a separate body part(4) and a nozzle part (5), which together mainly define a prechamber (3), which is connected to a main combustion space (7) of a cylinder (6) through nozzle openings (5a) of the nozzle part (5). According to the invention, the body part(4) is supported on the cylinder head (2) and provided with joint surfaces (4b) for supporting the nozzle part (5) on the body part(4).
Patent IL-104656-A0 (IL)
Title: Electrical shielded data connector
IPC: H01R13/658
Filed: 1993-02-09
Abstract: An electrical data connector includes a terminal support housing (4) carrying a plurality of electrical terminals (30). The housing (4) has at least one cable exit and a cable clamp (10) fixable to the housing (4), in the cable exit. The cable clamp (10) can be positioned in a plurality of orientations to provide a plurality of cable exit directions. <IMAGE>   <IMAGE>
Patent IL-128717-A0 (IL)
Title: Amino sulphone derivatives
IPC: C07C/
Filed: 1999-02-25
Abstract: The invention relates to an intermediate of formula (VI) <CHEM> or a protected derivative thereof, wherein Q is hydrogen or a carboxyl protecting group and Q' is a protecting group. Such intermediates are useful for the preparation of amidino sulphone derivatives which, in turn, have use as selective inhibitors of inducible nitric oxide synthase.
Patent IL-148127-A0 (IL)
Title: Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events
IPC: A61K31/00
Filed: 2000-08-30
Abstract: Use of an inhibitor of the renin-angiotensin system or a pharmaceutically acceptable derivative thereof, optionally together with an other antihypertensive, a cholesterol lowering agent, a diuretic or aspirin, in the manufacture of a medicament for the prevention of cardiovascular events; a method of preventing cardiovascular events comprising administering to a patient in need of such prevention an effective amount of an inhibitor of the renin angiotensin system or a pharmaceutically acceptable derivative thereof, optionally together with an other antihypertensive, a cholesterol lowering agent, a diuretic or aspirin; and a combination product containing an an inhibitor of the renin-angiotensin system or a pharmaceutically acceptable derivative thereof and a cholesterol lowering agent.
Patent IL-152647-A0 (IL)
Title: Building management system for monitoring site events at buildings
IPC: G06Q50/00
Filed: 2001-06-22
Abstract: A building events status network for monitoring building events such as the reporting of equipment failure and visits by third parties to a plurality of buildings replaces the traditional paper logs by providing at least one site terminal with a unique address at each building to be monitored. The terminals are connected at least to a remote web server at which a database is maintained of entry records such as fault logs, times of individuals using the site terminals to report a fault or record their access to a building in the network and status information concerning the nature and outcome of the event concerning the buildings. Preferably the internet is used as the network infrastructure and each terminal is provided with browser software that permits the user to access only the remote web server.
Patent IL-153309-A0 (IL)
Title: Method to detect modulators of vegf kinase domain
IPC: C07K14/71
Filed: 2001-06-06
Abstract: The present invention relates to assays for the detection of compounds with pharmacological activity, particularly for the detection of modulators of rat vascular endothelial growth factor receptor (rat VEGF-R2) kinase domain.
Patent IL-154776-A0 (IL)
Title: Method for the preparation of 21-hydroxy-6, 19-oxidoprogesterone and derivatives thereof
IPC: C07J71/00
Filed: 2001-09-17
Abstract: A method of preparing 21-hydroxy-6,19-oxidoprogesterone, or an acylated or phosphorlated version thereof.
Patent IL-165530-A0 (IL)
Title: Pasteurisation process for microbial cells and microbial oil
IPC: A61K8/92
Filed: 2004-12-02
Abstract: The present invention describes an improved pasteurisation protocol for pasteurising microbial cells is disclosed. The protocol has three stages, a first heating stage, a second plateau stage at which the cells are held at a (maximum and) constant temperature, and a third cooling stage. Both the heating and the cooling stages are rapid, with the temperature of the cells passing through 40 to 70°C in no more than 30 minutes in the heating stage. The heating rate is at least 0.5°C/minute and during cooling is at least -0.5°C/minute. The plateau maximum temperature is from 70 to 85°C. By plotting the pasteurisation protocol on a time (t, minutes) versus temperature (T, °C) graph, one obtains a trapezium having an area less than 13,000°C.minute. Not only does this result in a smaller energy input (and so a reduction in costs), but a better quality (and less oxidised) oil results having a peroxide value (POV) of less than 1.5 and an anisidine value (AnV) of less than 1.0.
Patent IL-187592-A0 (IL)
Title: Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
IPC: C07C69/96
Filed: 2007-11-22
Abstract: A capture compound and a method of identifying drug target non-target proteins in a mixture of proteins is provided, comprising the steps of interacting the mixture with a capture compound of the formula Q-Z-( Xm)-Yn, wherein Z is a trivalent moiety for presenting X, Y and Q; moiety X is selected to covalently bind to proteins; moiety Y is a pharmaceutical drug, drug fragment, drug metabolite, prodrug, enzyme substrate, enzyme inhibitor, transition-state analogue or a ligand to a receptor; Q is a sorting function selected to permit physical arraying or other addressable separation method suitable for analysis, Q comprises a biotin moiety, a (His) 6  moiety, a BODIPY moiety (4, 4-difluoro-4-bora-3a, 4a-diaza-s-indacene), an oligonucleotide or PNA (peptide nucleic acid), an antibody, an immunotoxin conjugate, an adhesive peptide, a lectin, an activated dextran or a peptide; and analyzing the captured proteins to identify drug target or drug non-target.
Patent RO-128821-A0 (RO)
Title: Semi-rigid structural elements and process for preparing the same
Inventor: OLARESCU ALIN
IPC: B27M3/00
Filed: 2013-04-05
Abstract: The invention relates to some structural semi-rigid elements obtained from wastes resulting from the lumber edging and to a process for producing the same, the structural elements being used in the wood industry. The claimed structural elements are produced by mechanically packing the lumber waste (1) by using some flexible connection elements (2). The claimed process consists in the following series of operations : cutting off the wastes (1) to the desired length with an additional oversizing of 20 mm, forming the packet, assembling the packet with the flexible connection elements (2), cutting off the packet to the final dimension, rough polishing followed by fine polishing.