baber/WOPTO huggingface dataset:
Patent CA-3041727-A1 (CA)
Inventor: HINCK ANDREW PETERSON
IPC: C07K14/495
Filed: 2017-11-17
Abstract: Recombinant transforming growth factor (TGF)-ß monomers modified to inhibit dimerization and block TGF-ß signaling are described. The recombinant TGF-ß monomers lack the ability to bind and recruit TGF-ß type I receptor (?ß?), but retain the capacity to bind the high affinity TGF-ß type II receptor (?ß??), and in some instances, include mutations that increase their affinity for ?ß??. Nucleic acid molecules and vectors encoding the recombinant TGF-ß monomers are also described. Isolated cells, such as T cells, can be re-programmed with a TGF-ß monomer-encoding nucleic acid or vector to secrete the monomer. Use of the recombinant TGF-ß monomers and/or cells producing the recombinant TGF-ß monomers, to inhibit TGF-ß signaling, such as to treat disorders associated with aberrant TGF-ß signaling, are also described.
Patent CA-3045522-A1 (CA)
Title: Systemes et procedes pour permettre le traitement d'objets dans des vehicules
Inventor: WAGNER THOMAS
IPC: B07C5/34
Filed: 2017-12-06
Abstract: L'invention concerne un système de traitement d'objet (10) dans une remorque (12) pour une remorque suiveuse. Le système de traitement d'objet (10) comprend une zone d'entrée (14) de la remorque, au niveau de laquelle des objets à traiter peuvent être présentés, un système de perception (22, 24, 26) pour fournir des données de perception concernant des objets à traiter, et un système de transport primaire (20) pour permettre le transport de chaque objet dans l'une parmi au moins deux directions de transport primaire dans la remorque (12) sur la base des données de perception.
Patent CA-3051284-A1 (CA)
Title: Co-crystals of substituted glycine compounds and uses thereof
Inventor: TSAI GUOCHUAN EMIL
IPC: C07D307/62
Filed: 2018-01-11
Abstract: The present disclosure provides co-crystals of a substituted glycine compound and a co-former compound of Formula (I), compositions comprising such, and uses thereof in treating and/or reducing the risk for a neuropsychiatricdisorder (e.g., schizophrenia, psychotic disorders, depressive disorders, suicidal ideation and/or behavior, obsessive compulsive disorderor Alzheimer's disease). Also provided herein are methods for preparing the co-crystals.
Patent CA-3052248-A1 (CA)
Inventor: LEE DANIEL
IPC: G06V30/224
Filed: 2017-05-12
Abstract: The present disclosure relates to the extraction of text from an image including a depiction of a document. According to one embodiment, a mobile device receives an image depicting a document. The mobile device identifies a plurality of text areas in the document and identifies a midpoint of each of the plurality of text areas in the document. The mobile device detects one or more lines of text in the document including a plurality of text areas, where the plurality of text areas included in a line of text are associated with a midpoint having a coordinate within a threshold number of pixels on one axis in a two-dimensional space. Based on an orientation of the detected one or more lines of text, the mobile device determines a probable orientation of the document and extracts text from the image based on the determined probable orientation of the document.
Patent CA-3053701-A1 (CA)
Inventor: KEMP GARY ALLAN
IPC: G06Q40/06
Filed: 2001-03-02
Abstract: A method and system for reducing the time it takes for a trader to place a trader when electronically trading on an exchange, thus increasing the likelihood that the trader will have orders filled at desirable prices and quantities. The "Mercury" display and trading method of the present invention ensure fast and accurate execution of trades by displaying market depth on a vertical or horizontal plane, which fluctuates logically up or down, left or light across the plane as the market prices fluctuates. This allows the trader to trade quickly and efficiently.
Patent CA-3054107-A1 (CA)
Title: Derives de quinoxaline et de pyridopyrazine utilises en tant qu'inhibiteurs de pi3k-beta
Inventor: ANGIBAUD PATRICK RENE
IPC: A61P37/00
Filed: 2018-03-29
Abstract: La présente invention concerne des dérivés de quinoxaline et de pyridopyrazine de formule (I) dans laquelle les variables ont la signification définie dans les revendications. Les composés selon la présente invention sont utiles en tant qu'inhibiteurs de pI3?ß. L'invention concerne en outre des compositions pharmaceutiques comprenant lesdits composés en tant que principe actif ainsi que l'utilisation desdits composés en tant que médicament.
Patent CA-3056146-A1 (CA)
Inventor: PALO JOSEPH DAN
IPC: F41A17/58
Filed: 2017-03-11
Abstract: The present invention provides an ammunition disabling system for selectively disabling ammunition that is operatively coupled to a selectively changeable material. In the operative state the material permits transmission of a percussive impact through the material for enabling firing of the ammunition; and in the deactivated state the material inhibits transmission of the percussion wave through the material for preventing firing of the ammunition. The ammunition disabling system includes an energy wave generator with an energy wave source that emits an energy wave at a frequency resonant a natural frequency of the material. When the ammunition with the material are exposed to the energy wave, the energy wave induces a response (physical and/or chemical) in the material that results in a mechanical change in the material from the operative state to the deactivated state by degrading the mechanical structure of the material.
Patent CA-3058192-A1 (CA)
Inventor: BORTELL PETER ISAAC
IPC: B32B15/20
Filed: 2018-04-27
Abstract: L'invention concerne des articles à bord partiellement ou entièrement scellé au moyen d'un ou de plusieurs revêtements comprenant un matériau polymère. L'article peut comprendre un revêtement choisi de sorte qu'une surface (par exemple, une surface de face) présente une propriété souhaitée (par exemple, un aspect, tel qu'un aspect chromé), et qu'une seconde surface (par exemple, une surface de face différente, ou une surface de bord) est recouverte d'un matériau différent, les différents revêtements fournissant une protection pour au moins la surface de bord. L'invention concerne également des matériaux de revêtement comprenant un constituant traceur. L'invention concerne également des procédés de revêtement d'un substrat. L'invention concerne également des procédés permettant de confirmer la présence d'un revêtement, en particulier sur une surface de bord.
Patent CA-3061420-A1 (CA)
Inventor: CRISTAU PIERRE
IPC: C07D487/04
Filed: 2018-04-27
Abstract: The present disclosure relates to fungicidal active compounds, more specifically to heteroarylphenylaminoquinolines and analogues thereof, processes and, intermediates for their preparation and use thereof as fungicidal active compound, particularly in the form of fungicide compositions. The present disclosure also relates to methods for the control of phytopathogenic fungi of plants using these compounds or compositions comprising thereof.
Patent CA-3062967-A1 (CA)
Title: An electrical assembly for detecting dielectric breakdown in direct current power transmission medium
Inventor: CANELHAS ANDRE
IPC: G01R31/08
Filed: 2018-04-26
Abstract: In the field of power transmission networks, particularly high voltage direct current (HVDC) power transmission networks, there is provided an electrical assembly (10). The electrical assembly (10) comprises a converter (12) that includes at least one AC terminal (14A, 14B, 14C) for connection to an AC network (16) and at least one DC terminal (18, 22) which is operatively connected to a DC power transmission medium (20, 24). The electrical assembly (10) also includes a signal injection circuit (32) which is operatively coupled with at least one DC power transmission medium (20, 24). The signal injection circuit (32) includes a signal generator (38) to selectively inject a plurality of different frequency signals into the said at least one transmission medium (20, 24). In addition the signal injection circuit (32) includes a signal analyser (42) to establish a response signature of the said at least one transmission medium (20, 24) to the plurality of different frequency injected signals. The signal injection circuit (32) also includes a control unit (46) that is programmed to detect a dielectric breakdown in the said at least one transmission medium (20, 24). More particularly the control unit (46) is programmed to control the signal generator (38) to inject a plurality of different frequency signals into the said transmission medium (20, 24), retrieve the corresponding response signature of the said transmission medium (20, 24) from the signal analyser (42), and compare the response signature to a plurality of reference signatures corresponding to dielectric breakdown and non-breakdown conditions in the said transmission medium (20, 24).
Patent CA-3066161-A1 (CA)
Inventor: Sidorov Aleksandr Stalevich
IPC: G21C9/016
Filed: 2018-12-28
Abstract: The invention relates to the field of nuclear energy, in particular, to systems that ensure the safety of nuclear power plants (NPPs), and can be used in severe accidents resulting in molten core, destruction of the reactor vessel and molten metal output into the containment volume of NPP. The technical result of the claimed invention is to increase the reliability of the reactor molten core localization device. The technical result of reactor molten core localization device is achieved due to the lower support consisting of radial supports of a horizontal embedded slab and radial supports installed in the lower part of the molten metal trap casing joined together by clamps, while the radial supports and the fasteners have oval shaped openings.
Patent CA-3067250-A1 (CA)
Inventor: ZHOU CHUNHONG (ALLEN)
IPC: G02B7/28
Filed: 2019-01-10
Abstract: L'invention concerne un système d'imagerie pouvant comprendre une platine dotée d'une surface destinée à supporter un échantillon devant être scanné par le système d'imagerie; un étage optique doté d'une lentille d'objectif, l'étage optique pouvant être positionné par rapport à la platine; un actionneur couplé physiquement à au moins la platine ou l'étage optique pour déplacer la platine par rapport à l'étage optique; un circuit d'asservissement permettant de commander l'actionneur; un premier ensemble de paramètres de commande permettant de commander le circuit d'asservissement; un deuxième ensemble de paramètres de commande permettant de commander le circuit d'asservissement; et un circuit de servocommande permettant d'appliquer le premier ensemble de paramètres de commande au circuit d'asservissement lorsque le système d'imagerie fonctionne dans un premier mode de fonctionnement et d'appliquer le deuxième ensemble de paramètres de commande au circuit d'asservissement lorsque le système d'imagerie fonctionne dans un deuxième mode de fonctionnement.
Patent CA-3068318-A1 (CA)
Inventor: JOHNSON JEREMIAH A
IPC: C07D405/14
Filed: 2018-06-29
Abstract: L'invention concerne des procédés, des compositions, des réactifs, des systèmes et des kits pour préparer et utiliser des macromonomères multifonctionnels ramifiés, qui contiennent un groupe norbornène polymérisable par métathèse à ouverture de cycle, un ou plusieurs sites réactifs susceptibles d'être soumis une chimie click, et un groupe acyle terminal susceptible d'être soumis à une réaction de couplage ; des macromonomères multichargement ramifiés ; et les polymères correspondants. Divers modes de réalisation montrent que les macromonomères et les polymères de la présente invention présentent une régulation sans précédent de la charge de chargement des agents. Ces matériaux ont le potentiel d'être utilisés pour le traitement de maladies et d'affections tels que le cancer et l'hypertension.
Patent CA-3070221-A1 (CA)
Title: Compositions nanogalvaniques a base d'aluminium utiles pour la production d'hydrogene gazeux et leur traitement a basse temperature
Inventor: DARLING KRISTOPHER ALLEN
IPC: C22C21/00
Filed: 2018-07-23
Abstract: L'invention concerne des alliages constitués d'une microstructure affinée, ultrafine ou à l'échelle nanométrique, qui, lorsqu'ils sont amenés à réagir avec de l'eau ou un quelconque liquide contenant de l'eau, produisent spontanément et rapidement de l'hydrogène à température ambiante ou élevée. Ces métaux, appelés ici alliages nanogalvaniques à base d'aluminium, ont des applications qui comprennent, entre autres, la production d'énergie à la demande. Les alliages peuvent être composés principalement d'aluminium et d'autres métaux, par exemple d'étain, de bismuth, d'indium, de gallium, de plomb, etc. et/ou de carbone, ainsi que de mélanges et alliages de ceux-ci. Les alliages peuvent être traités par broyage à boulets dans le but de synthétiser des charges d'alimentation en poudre, chaque particule des poudres ayant les caractéristiques mentionnées ci-dessus. Ces poudres peuvent être utilisées sous leur forme naturelle ou consolidées à l'aide de techniques disponibles dans le commerce dans le but de fabriquer des composants fonctionnels utiles.
Patent CA-3070805-A1 (CA)
Inventor: Li yong-xin
IPC: A61K45/00
Filed: 2018-07-27
Abstract: Prostacyclin (PGI2) analogues which are agonists of the prostacyclin receptor (PI) are demonstrated to activate lipolytic activity in adipocytes. Also described are pharmaceutical compositions and methods for using the PGI2 receptor agonists to reduce subcutaneous adipose tissue and to treat or reduce symptoms of obesity-related diseases or disorders such as diabetes mellitus, fatty liver disease and cardiovascular disease.
Patent CA-3074802-A1 (CA)
Inventor: GUNDE TEA
IPC: C07K16/18
Filed: 2018-10-09
Abstract: The present invention relates to an isolated antibody which specifically binds human PDL1, and pharmaceutical compositions and methods of use thereof. The present invention further relates to a nucleic acid encoding said antibody, a vector comprising said nucleic acid, a host cell comprising said nucleic acid or said vector, and a method of producing said antibody.
Patent CA-3075662-A1 (CA)
Title: Antimicrobial composition
Inventor: GUYONNET JEROME
IPC: A61K31/609
Filed: 2018-09-14
Abstract: The present invention relates to a new topical composition comprising niclosamide and/or oxyclozanide and to the use of said composition for the treatment or prevention of pyoderma or dermatitis in non-human mammals.
Patent CA-3078828-A1 (CA)
Inventor: ZHANG ZHI
IPC: H04W72/04
Filed: 2017-10-11
Abstract: Selon un mode de réalisation, la présente invention concerne un procédé et un dispositif de communication sans fil, susceptibles d'accroître les performances de communication dans la transmission d'un bloc de signal de synchronisation. Le procédé comprend les étapes suivantes : un dispositif de réseau, occupant une première largeur de bande sur N premiers symboles, envoie un premier canal ou signal compris dans un bloc SS à un dispositif terminal, N étant un nombre entier supérieur ou égal à 1 ; et le dispositif de réseau, occupant une seconde largeur de bande sur M seconds symboles et occupant une troisième largeur de bande sur S premiers symboles parmi les N premiers symboles, envoie un second canal ou signal compris dans le bloc SS au dispositif terminal, les positions de ressources dans le domaine fréquentiel de la première bande passante et de la troisième bande passante ne se chevauchant pas, et M et S étant des nombres entiers supérieurs ou égaux à 1.
Patent CA-3081418-A1 (CA)
Inventor: CHEN WEIHU
IPC: H05B47/19
Filed: 2020-05-28
Abstract: A dummy load circuit for a single live wire switch includes: a switch circuit -at least a first resistor and a switch are connected in the switch circuit, wherein the first resistor is connected to the switch, such that the first resistor is connected to the dummy load circuit through the switch; and a switch control circuit - the switch control circuit at least includes a switch control device, wherein the switch control device is connected to the switch to facilitate power-on/off control. The dummy load circuit may be connected in parallel with an electrical load.
Patent CA-3083071-A1 (CA)
Inventor: GRAY BENJAMIN NEIL
IPC: C12N15/82
Filed: 2018-11-20
Abstract: Compositions and methods for improving plant growth are provided herein.  Polynucleotides encoding quinone oxidoreductase proteins, polypeptides encompassing quinone oxidoreductase proteins, and expression constructs for expressing genes of interest whose expression may improve agronomic properties including but not limited to crop yield, biotic and abiotic stress tolerance, and early vigor, plants comprising the polynucleotides, polypeptides, and expression constructs, and methods of producing transgenic plants are also provided.
Patent CA-3086554-A1 (CA)
Inventor: MCCLOSKEY JENNY COLLEEN
IPC: A61M31/00
Filed: 2018-12-05
Abstract: A device (10,210) for treatment of a canal associated with an orifice includes a flexible stem portion (20, 220) adapted for insertion along the canal and having an expandable member (24, 224) carried by the stem portion (20, 220) at or adjacent the distal end. The expandable member (24, 224) is for occlusion of an inner end region of the canal. A cap (40, 240, 340) mounted on the stem portion (20, 220), configured as a receptacle (42, 242), to close an outer end of the canal and to accommodate the surface(s) about the outer end of the canal. The cap (40, 240) thereby defines with the expandable member (24, 224), a treatment zone, wherein the receptacle (42, 242) is adapted to receive and store treatment fluid for contact with the surface(s) about the outer end of the canal.
Patent CA-3087453-A1 (CA)
Inventor: VIOLAS DE OLIVEIRA E SA PEDRO AMERICO
IPC: B65D65/38
Filed: 2019-02-26
Abstract: The present invention relates to an agricultural mesh for baling (1) comprising columns of chains or pillars ( 3), wherein each column of chain or pillar ( 3) comprises a plurality of meshes ( 4) interconnected with each other and associated with the columns of chains or pillars (3) by means of the wefts (2), wherein the configuration and dimensions of the wefts (2) provides the reinforcement of the agricultural mesh for baling (1). The present invention provides a solution that aims to reduce the dimensions of the longitudinal openings wefts ( 2) during the baling process, yielding strong and well- preserved bales.
Patent CA-3088191-A1 (CA)
Inventor: BLUM NATHAN
IPC: A01K39/06
Filed: 2019-01-24
Abstract: L'invention concerne des systèmes de distribution d'un produit dans le tube digestif d'un oiseau, par son bec ouvert, et leurs procédés d'utilisation. La présente invention concerne des appareils d'ouverture de bec et leurs procédés d'utilisation.
Patent CA-3089844-A1 (CA)
Inventor: SHVETSOV KYRYLO
IPC: B01D46/00
Filed: 2019-11-21
Abstract: Presented are an apparatus and method for fluid evacuation. An exemplary fluid evacuation system includes a surgical apparatus having a fluid conduit therethrough. The fluid conduit includes a gaseous fluid sorbent material. Additionally, the fluid conduit is fluidly coupled with a vacuum tube fluidly coupled with a vacuum source, wherein the vacuum source is operable to create a flow of fluid through the surgical apparatus fluid conduit and the vacuum tube.
Patent CA-3090280-A1 (CA)
Inventor: ALLAN KEVIN MCCORMACK
IPC: C07D339/06
Filed: 2019-02-15
Abstract: The present disclosure relates to methods and intermediates for the synthesis of novel compounds for use in the treatment of a Retroviridae viral infection, including an infection caused by the HIV virus. The present disclosure relates to processes and intermediates useful for preparing a compound of formula I: or a co-crystal, solvate, salt or combination thereof.
Patent CA-3092740-A1 (CA)
Inventor: CORREA ROCHA RAFAEL
IPC: C12N5/0783
Filed: 2019-03-01
Abstract: The present invention provides an in vitro method for obtaining and purifying regulatory T cells from thymic tissue (or thyTreg cells), which makes it possible to obtain more than 10 billion cells from a single thymus. These thyTregs obtained in the invention have a purity of more than 95% and very high suppressive capacity, survival and viability, in addition to being safe from a clinical viewpoint. The foregoing would not require the use of massive ex vivo cell expansion protocols. The transfer of these thyTreg cells to patients enables immune tolerance induction. Thus, said cells may be used as cell therapy to induce immune tolerance in the treatment and/or prevention of transplant rejections and in autoimmune diseases.
Patent CA-3093234-A1 (CA)
Inventor: LIU JIWEN
IPC: C07D473/06
Filed: 2019-03-05
Abstract: L'invention concerne des composés, des compositions, des formulations et des procédés de modulation du récepteur de l'adénosine A2B.
Patent CA-3095040-A1 (CA)
Title: Traitement de maladies par modulation ciblee de reseaux de signalisation genique
Inventor: BUMCROT DAVID A
IPC: A61K33/24
Filed: 2019-04-08
Abstract: La présente invention concerne des procédés et des compositions pour traiter un patient atteint d'une maladie génétique, telle que notamment la glomérulopathie à dépôts de fibronectine et la coproporphyrie héréditaire. L'invention concerne également des procédés et des compositions pour moduler le ou les gènes associés à la maladie par modification de réseaux de signalisation génique.
Patent CA-3095806-A1 (CA)
Inventor: WANG JIANFEI
IPC: G01J9/00
Filed: 2020-10-09
Abstract: Disclosed are the method and system to derive the wavelength/frequency information covering wide wavelength or frequency range. Its practical applications include both fixed wavelength optical signal and wide bandwidth tunable or non-tunable optical signal, where the wavelength/frequency information is necessary for optical signal calibration, control, and monitoring, optical communications, and data processing. The approach has a "self-compensation" feature which is preferred to improve the accuracy of the extracted wavelength or frequency information even though there are components in the system having strong wavelength or frequency dependence in the wide wavelength or frequency range. The method is generic which can be realized in free space, fiber, or photonic integrated circuit (PIC).
Patent CA-3101758-A1 (CA)
Title: Weed seed destruction with a horizontal transfer member
Inventor: MAYERLE DEAN
IPC: A01F12/44
Filed: 2016-07-13
Abstract: Weed seeds are destroyed in the chaff from a combine harvester by repeated high speed impacts caused by a rotor mounted in one of a pair of side by side housings which accelerate the discarded seeds in a direction centrifugally away from the rotor onto a stator including angularly adjustable stator surfaces around the axis. Thus the discarded seeds rebound back and forth between the rotor and the stator to provide a plurality of impacts. The seeds are carried axially of the rotor by a controlled airstream so that they move to an axial discharge location where a discharge fan is mounted. The angle of the discharge around the rotor axis can be changed to direct the seeds to the side of the combine away from a straw chopper, towards the guide fins of the tailboard of the chopper, or into the housing of the straw chopper.
Patent CA-3103406-A1 (CA)
Inventor: VERMA SUMIT
IPC: B67D7/02
Filed: 2019-06-06
Abstract: A unit dose container production system (10) is disclosed where a unit dose container (130) is evacuated and thereafter loaded with a radioactive fluid while remaining at a single location. In this regard, the production system (10) uses a first conveyor (12) to sequentially load unit dose containers (130) into an empty container receptacle (24) of a second conveyor (20) at a first location (90). The second conveyor (20) may be operated to dispose a container receptacle (24) at each of the first location (90), a second location (100), and a third location (110). A unit dose container (130) at the second location (100) is evacuated and thereafter loaded with a radioactive fluid, and is thereafter moved to a third location (110) by the second conveyor (20). The unit dose container (130) is removed from the second conveyor (20) at the third location (110), and thereafter the radioactivity content of a unit dose container (130) may be determined, such as at an ionization chamber or the like.