baber/WOPTO huggingface dataset:
Patent EP-4289476-A2 (EP)
Title: Methods of treating fabry disease in patients having a mutation in the gla gene
Inventor: BENJAMIN ELFRIDA
IPC: A61P3/00
Filed: 2019-01-16
Abstract: Provided are methods of treating a patient diagnosed with Fabry disease and methods of enhancing α-galactosidase A in a patient diagnosed with or suspected of having Fabry disease. Certain methods comprise administering to a patient a therapeutically effective dose of a pharmacological chaperone for α-galactosidase A, wherein the patient has a mutation in the nucleic acid sequence encoding α-galactosidase A. Also described are uses of pharmacological chaperones for the treatment of Fabry disease and compositions for use in the treatment of Fabry disease.
Patent EP-4286634-A2 (EP)
Inventor: DUER STEFAN
IPC: E05D15/58
Filed: 2021-05-31
Abstract: Führungssystem (8) zur Führung wenigstens eines bewegbar gelagerten Türflügels (4) relativ zu wenigstens einem feststehenden Möbelteil (7a), umfassend:- wenigstens eine an dem wenigstens einen Möbelteil (7a) anzuordnende Führungsschiene (9c),- wenigstens eine Führungsvorrichtung (12), an welcher der wenigstens eine Türflügel (4) schwenkbar lagerbar ist, wobei die wenigstens eine Führungsvorrichtung (12) zwischen einer eingefahrenen und einer ausgefahrenen Endstellung entlang der wenigstens einen Führungsschiene (9c) bewegbar gelagert ist,- wenigstens eine Blende (11) zur Abdeckung wenigstens einer Stirnseite (15) der wenigstens einen Führungsschiene (9c), wobei die wenigstens eine Blende (11) zumindest zwischen einer ersten Betriebsstellung, in welcher die Blende (11) die wenigstens eine Stirnseite (15) der wenigstens einen Führungsschiene (9c) zumindest bereichsweise abdeckt, und einer zweiten Betriebsstellung, in welcher die wenigstens eine Blende (11) die wenigstens eine Stirnseite (15) zumindest bereichsweise freigibt, bewegbar ist, und- wenigstens eine Betätigungsvorrichtung (18), mit welcher die wenigstens eine Blende (11) zumindest aus der ersten in die zweite Betriebsstellung bewegbar ist,wobei wenigstens eine Koppelvorrichtung (19) vorgesehen ist, mit welcher die wenigstens eine Führungsvorrichtung (12) mit der wenigstens einen Betätigungsvorrichtung (18) in einem der ausgefahrenen Endstellung, vorzugsweise unmittelbar, vorgelagerten Teilabschnitt der wenigstens einen Führungsschiene (9a) lösbar koppelbar ist, wobei die wenigstens eine Betätigungsvorrichtung (18) in einem gekoppelten Zustand mit der wenigstens einen Führungsvorrichtung (12) von der wenigstens einen Führungsvorrichtung (12) mitnehmbar ist, um die wenigstens eine Blende (11) aus der ersten in die zweite Betriebsstellung zu bewegen.
Patent EP-4292632-A2 (EP)
Inventor: ALSHAIBA SALEH GHANNAM ALMAZROUEI MOHAMMED
IPC: A61M16/00
Filed: 2019-12-15
Abstract: The invention relates to an ultrasonic mist inhaler, comprising:- a liquid reservoir structure comprising a liquid chamber adapted to receive liquid to be atomized,- a sonication chamber in fluid communication with the liquid chamber,- a capillary element arranged between the liquid chamber and the sonication chamberwherein the capillary element is a material at least partly in bamboo fibers as depicted in Figure 3.
Patent EP-0006612-A2 (EP)
Inventor: MCCORD JAMES W
IPC: B01D5/00
Filed: 1979-06-26
Abstract: A vapor generating and recovering apparatus for vaporizing a liquid and condensing a vapor, the apparatus including a container having a liquid therein with a heating and cooling system in heat transfer relation with the liquid and vapor in the container. The heating and cooling system includes means to vaporize the liquid; means to condense the vaporized liquid; and, means to compress a refrigerant. The means to compress the refrigerant is in fluid communication on its high pressure side with the means to vaporize a liquid or heat a liquid and on its low pressure side with the means to condense or cool a liquid. The heating and cooling system further includes a complementary condenser system on the high pressure side of the means to compress a refrigerant, discharging its heat external to said apparatus.
Patent EP-0026854-A2 (EP)
Inventor: LLOYD ROBERT
IPC: B01D53/60
Filed: 1980-09-11
Abstract: The production of high pressure clean gas from hydrocarbon fuels such as pulverised coal has many problems most of which lie in the cleaning of the gas stream. A process and apparatus are provided which propagate gas at a temperature of up to 2700° F and a pressure of 3000 p.s.i. By operating the process of a high pressure and density it is possible to clean a smaller volume of gas using low flowrate apparatus. Activated carbon filters are used to clean the gas and convert excess oxygen and nitric oxides to carbon dioxide and nitrogen, thus reducing the pollutant content of the gas.
Patent EP-0019386-A2 (EP)
Inventor: SHEETS JESSE EUGENE
IPC: F23C99/00
Filed: 1980-04-28
Abstract: Method and apparatus for reducing the concentration of NOx emissions of a flame having a temperature above 925°C (1700°F), especially a flame of the oil-fired and air-sustained kind, by causing at least portion of the post ignition combustion products of the flame to flow in a non-turbulent, preferably laminar, pattern. The apparatus may comprise an array of spaced vanes some of which are preferably planar and some of which are preferably shaped to impose a curved flow path on said products.
Patent EP-0026590-A2 (EP)
Inventor: WHEATLEY NIGEL JOHN
IPC: G06F21/62
Filed: 1980-09-05
Abstract: The use of protected capability registers to hold the physical base and limit addresses and access rightsfora block of memory and the way in which such registers are loaded using System Capability Tables and reserved segment pointer tables is well known in the prior art. In the present invention the normal capability load instruction has been enhanced in four majorways:-
     a) allowing additional capability classes to be handled   b) instituting a "load on use" facility   c) instituting capability propagation control and   d) implementing access reduction facilities   
     The capability classes comprises (i) system store, (ii) system resource (iii) local store and (iv) passive capability. The "load on use" facility speeds up the load capability instruction and the change process instruction. The propagation control mechanism introduces an access bit which controls the storing of the capability pointer preventing the passing of the pointer from one process to another whereas the hardware access reduction facility enables a capability to be loaded into a a capability register with reduced access right.
Patent EP-0036560-A2 (EP)
Inventor: HOKI TSUNEO
IPC: C08J9/04
Filed: 1981-03-10
Abstract: Substantially closed-cell aliphatic olefin polymer foams having improved dimensional stability are provided by the inclusion of from 0.1 to 10 weight percent, based on olefin polymer, of an N-higher aliphatic hydrocarbyl substituted amide of a C 1 -C 8  aliphatic carboxylic acid.
Patent EP-0037558-A2 (EP)
Inventor: DUDLEY PETER B
IPC: A63B21/02
Filed: 1981-04-01
Abstract: A mono-kinetic exercise device 5, 110,210, for mounting within a doorway or other rectangular aperture. The exercise device includes brackets (10, 12, 14, 16, 114, 214) of various types for attachment of the device to the door frame (6,8,112, 212), tensioning devices (36, 38, 132, 232), one or more ropes (32, 34, 120, 220) extending lengthwise along the device (5, 110, 210) and a grasping bar (30,122,222,322,) grasped by the person desiring exercise which may be moved upward or downward within the doorway such that the movement entails an effort by the exerciser and provides muscle exertion.
Patent EP-0038475-A2 (EP)
Inventor: HOECKELE MAX
IPC: H01B17/40
Filed: 1981-04-09
Abstract: Fitting for the manufacture of a junction with a glass fibre-reinforced synthetic rod (1) that can be loaded with a high-tensile force, in particular an insulating rod for free high-tension lines, which has a terminal sleeve (3; 103; 203) of a cone terminal (3,6; 103,106; 203,206) as well as a first terminal (2; 102;202), gripping the end section of the plastic rod, on its side directed away from the adjacent end of the insulating rod (1; 101; 201). The housing (6; 106; 206) of this cone terminal holding the terminal sleeve (3; 103) is designed as a tensile force transmission member. The terminal sleeve (3; 103, 203) and the first terminal (2; 102; 202) are supported, at least indirectly, on one another in the axial direction. <IMAGE>
Patent EP-0072373-A2 (EP)
Inventor: CHEVILLAT PIERRE DR
IPC: G06F7/00
Filed: 1981-08-19
Abstract: A microprocessor having a single common data bus (17) to which the output (33) of the arithmetic-logic unit (11) as well as input and output of the data memory (13) are connected without intermediate buffer registers. Of the working registers (21, 23, 25, 27) connected to ALU inputs, one group (21, 23) is loaded from the common data bus and the other group (25, 27), used as accumulators, is directly loaded from the ALU output. Specific control circuitry (51, 53, 55, 57, 59, 61) allows selective storing of ALU output values Into accumulators (25, 27), and simultaneous transfer with selective scaling Into another register and into an addressed memory location within the same cycle during which the instruction was executed.
Patent EP-0053458-A2 (EP)
Inventor: MOODY GEORGE WILLIAM
IPC: F03B13/14
Filed: 1981-11-20
Abstract: A device and a method for extracting energy from waves on a liquid from the oscillations of a column 14 of liquid in a chamber 22. The oscillations are caused by an oscillatory excitation force 'Fe' produced by the effect of the waves. The phase of the velocity 'z' of the column 14 of liquid and the phase of the excitation force 'Fe' are brought substantially into phase by arresting the motion of the column 14 of liquid, and holding the column 14 of liquid stationary until the column 14 of liquid can be released in phase with the excitation force 'Fe'.
Patent EP-0058397-A2 (EP)
Inventor: SUZUKI SUGURU
IPC: A61P7/02
Filed: 1982-02-11
Abstract: An anticoagulant composition containing.heparin having low antithrombin III affinity as an effective ingredient is described. 
     There is also disclosed the use of said anticoagulant composition for treating a mammal by intravenous administration or intramuscular injection to induce coagulation of the circulating blood.
Patent EP-0071863-A2 (EP)
Inventor: KUHLE ENGELBERT DR
IPC: C07D209/76
Filed: 1982-07-26
Abstract: Die neuen N-(Dichlorfluormethylthio)-3,6-endomethylen-Δ<4>-tetrahydrophthalimide können aus 3,6-Endomethylen-Δ<4>-tetrahydrophthalimid mit Dichlorfluormethansulfenylchlorid in Gegenwart eines säurebindenden Mittels in Lösung hergestellt werden. Sie können als mikrobizide Mittel verwendet werden.
Patent EP-0073028-A2 (EP)
Inventor: HAYASHI YOSHIMASA
IPC: F02P5/152
Filed: 1982-08-19
Abstract: An automotive internal combustion engine comprises a cylinder block having at its bottom part with a plurality of main bearings, a bearing beam structure secured to the bottom part of the cylinder block and including a plurality of main bearing cap sections each of which associates with each main bearing of the cylinder block to rotatably support a crankshaft, and at least a beam section for securely connecting the bearing cap sections with each other, and an engine knock sensor for detecting engine knock and located at a part of the bearing beam structure, thereby sensitively detecting engine knock while effectively reducing engine noise.
Patent EP-0075946-A2 (EP)
Inventor: NIINO SHUHEI MITSUBISHI DENKI
IPC: B21B37/18
Filed: 1982-09-29
Abstract: A dimension control device for continuous rolling machine includes a correction mechanism for correcting a set tension of the rolling machine in accordance with temperature variations of a rolling material. With such a dimension control device, the width of the rolling material is controlled to a constant at all times regardless of any variation in the temperature.
Patent EP-0086874-A2 (EP)
Inventor: FICKELSCHER KURT
IPC: G01G3/14
Filed: 1982-10-26
Abstract: The application relates to a force transducer with a connecting rod system in two planes. One plane of the connecting rod system is formed by two connecting springs arranged in a V shape and the other plane by the measuring spring. This force transducer with integrated guide function is extremely cheap to manufacture and has a good level of accuracy. <IMAGE>
Patent EP-0064833-A2 (EP)
Inventor: ATKINSON ANTHONY
IPC: B01D15/08
Filed: 1982-04-26
Abstract: A process for the high pressure liquid affinity chroma- tographis separation of at least one biological or related substance from a mixture in which the contact, washing and eluting phases are performed on a binding material made from a ligand. contair'.ig at least one of the groups anthraquinone, phthalocyanine or aromatic azo, coupled to a matrix through a spacer arm, the binding material being so constructed that at least one biological or related substance is retained on the binding material during the contact and washing phases. In one preferred embodiment the ligand is a reactive dye. especially a triazinyl dye, the matrix is agarose or silica and the spacer arm is a substituted aminohexyl group. The chromatographic procedure is preferably performed at 100-3500 p si, at a flow rate of 0.5-2.0ml/min. The choice of washing and eluting solutions depends on the material to be separated. However buffer solution to wash the column and a desorbing agent to elute the material are preferred. When the biological substance is an enzyme the desorbing agent is preferably an enzyme substrate, cofactor, inhibitor or analogue thereof.A binding material for use in the above HPLAC procedure is also provided. This is made from a ligand containing at least one of the groups anthraquinone, phthalocyanine or aromatic azo, coupled to a matrix through a spacer arm.
Patent EP-0073710-A2 (EP)
Inventor: CATILLER ROBERT DOUGLAS
IPC: G06F13/38
Filed: 1982-08-19
Abstract: Base connection modules are used to house slide-in cards which form a Network Support Processor which executes data transfer operations for up to four main host computers. One Network Support Processor can control up to four Line Support Processors, each one of which manages up to 16 Line Adapters connected, via data communication lines, to remote terminals. The Line Support Processor, via its Line Adapters, handles a wide variety of communication line disciplines but provides a common discipline to its Network Support Processor and the host computer.
Patent EP-0090362-A2 (EP)
Inventor: HENNING RAINER DR
IPC: A61K31/4035
Filed: 1983-03-24
Abstract: Compounds of the formula I <IMAGE>  in which    n = 1, 2 or 3,   R<1> is hydrogen, unsubstituted or amino-, acylamino- or benzoylamino-substituted alkyl, alkenyl, cycloalkyl, cycloalkenyl, cycloalkylalkyl, aryl or partially hydrogenated aryl each of which can be substituted by alkyl, alkoxy or halogen, arylalkyl which as defined above can be substituted in the aryl radical, a mono- or bicyclic heterocyclic radical having up to 10 ring atoms, 1 to 2 ring atoms of which can be sulphur or oxygen atoms and/or 1 to 4 ring atoms of which represent nitrogen atoms or an amino acid side chain,    R<2> is hydrogen, alkyl, alkenyl or arylalkyl,    Y is hydrogen or hydroxyl,    Z is hydrogen or    Y and Z together are oxygen and   X is alkyl, alkenyl, cycloalkyl, aryl which can be mono-, di- or trisubstituted by alkyl, alkoxy, hydroxyl, halogen, nitro, amino, alkylamino, dialkylamino or methylenedioxy, or indol-3-yl, a process for their preparation, agents containing them, their use as well as intermediates and a process for their preparation.
Patent EP-0098522-A2 (EP)
Inventor: KANEKO MASAHARU
IPC: C09B29/036
Filed: 1983-06-29
Abstract: A liquid crystal composition of the guest-host type contains a pleochroic dye dissolved therein. The dye molecule has an end group or end groups in the molecule represented by the general formula: 
<CHEM>
 wherein Ro designates a straight chain alkyl group, in which methylene groups not adjacent to the nitrogen atom may be substituted by oxygen atom or sulfur atom; R1 designates an alkyl group having a chain length different from the alkyl group of Ro or a group 
<CHEM>
 in R1 a methylene group not adjacent of the nitrogen atom may be substituted by an oxygen atom or sulfur atom, and R2 designates a hydrogen atom, an alkyl group, alkoxy group, cycloalkyl group or dialkylamino group.
Patent EP-0102704-A2 (EP)
Inventor: PIOTROSKI PETER N
IPC: B07C1/00
Filed: 1983-07-01
Abstract: 57 A method and associated apparatus is disclosed for automatically providing a complete document collation during start up and shut down of a multi-station document inserter. The steps involved are initiating a Sequence Start Routine during start up of the inserter in which each feeder module is activated sequentially beginning with the document feeder module most remote from the envelope feeder module and entering with the feeder module closest to the envelope feeder module, and initiating a Clear Deck Routine during shut down of the document inserter in which each feeder module is deactivated sequentially beginning with the document feeder module most remote from the envelope feeder module and ending with the feeder module closest to the envelope feeder module.
Patent EP-0102820-A2 (EP)
Inventor: FOSTER THOMAS VINCENT
IPC: C03B9/38
Filed: 1983-08-30
Abstract: The movable side portions (70; 110) of a mould of a cyclicly operating glassware forming machine have cooling passages (80; 114) passing inwardly therein from an entrance in a bottom surface of the side portion. A plenum chamber (18; 88; 128,130; 228. 260, 262) is formed beneath the side portions and has upwardly opening exits (56; 96; 256) which communicate with the entrances of the cooling passages when the side portions are stationary in either an open or a closed position thereof so that cooling air can pass into the cooling passages. In this way, each cooling passage can be supplied with air at substantially the same pressure and low pressure air can be used.
Patent EP-0110516-A2 (EP)
Inventor: BLACK WILLIAM BROWN
IPC: E04G1/28
Filed: 1983-09-28
Abstract: A modular block is the key component of scaffolding for use in restricted working spaces such as are encountered in the building of coke ovens. 
     The scaffolding comprises a plurality of columns (8) spaced at regular intervals along the length of the working space (9) and each built up from a set of modular blocks (12 to 15). The modular blocks are preferably of a framed construction, injection moulded from a high-density thermoplastic polymer, and structured to give high resistance to crushing. The blocks (12 to 15) of each set are all of the same external transverse horizontal dimensions and each is fashioned at its underside with a depending peripheral flange (16) and at its upper side with an inset peripheral ledge (17). The modular blocks (12 to 15) of each set differ in flange and ledge widths with the ledge width of each greater than the flange width and the peripheral flange (16) of each upper block (13, 14 and 15 respectively) in a column (8) snugly fitting on to the peripheral ledge (17) of the block (12, 13 and 14 respectively) immediately therebelow in the column.
Patent EP-0106601-A2 (EP)
Inventor: IKEDA YOSHIAKI
IPC: G09G5/02
Filed: 1983-09-29
Abstract: A plurality of picture RAMs (32R, 32G, 32B) are synchronously accessed by a CRT controller (35), and the priority levels of the outputs from the picture RAMs (32R, 32G, 32B), are specified by priority specifying means (34). A priority circuit (33) inputs thereinto the outputs of the picture RAMs (32R, 32G, 32B) and selects the Inputs in accordance with the specified priority levels for output to a color display (37). The color display (37) displays, on its CRT screen, graphic forms in colors determined by a combination of the picture RAMs (32R, 32G, 32B). A feedback circuit feeds the output of the priority circuit back to the picture RAMS (32R, 32G, 32B), and data update control means (39) which specifies which one of the picture RAMs (32R, 32G, 32B) is to be rewritten with the output of the feedback circuit are provided. By hardware processing, the stored content of a desired one of the picture RAMs (32R, 32G, 32B) is thus rewritten with the output of the priority circuit (33).
Patent EP-0118807-A2 (EP)
Inventor: LASKARIS EVANGELOS TRIFON
IPC: A61B10/00
Filed: 1984-02-21
Abstract: A superconducting magnet includes a coil support; structure comprising a body formed of a generally-cylindrical wall. The body includes at least a pair of surfaces facing inwardly of said body, each being of generally-cylindrical shape and each being adapted to abut the radially-outer surface of a respective one of a pair of ring-shaped, superconductive coils. The support structure comprises a material such as aluminum which is adapted to shrink around the coils as the body and coils are cooled to a cryogenic temperature, so as to provide interference fits between the body and the coils. To prevent movement of the coils towards each other due to magnetic attraction forces therebetween, the body includes a pair of shoulders extending inwardly from respective adjacent edges of the pair of inwardly-facing surfaces. The shoulders are adapted to abut confronting surfaces of the pair of coils to prevent the coils from moving towards each other.
Patent EP-0118917-A2 (EP)
Inventor: TANIYAMA TADAYOSHI
IPC: C12N5/16
Filed: 1984-03-12
Abstract: A method of producing biologically active substances using a hybrid cell line obtained by fusing (1) a human tumor cell line which does not grow in a medium containing aminopterin or/and azaserine or a cell line derived therefrom with (2) a human-tumor macrophage. The human tumor macrophage cell line may be either a thymidine kinase-deficient cell line of U-937 or a thymidine kinase-deficient cell line of THP-1, the non-tumor macrophage may be alveolar macrophage, splenic macrophage, peripheral blood monocyte, peritoneal macrophage, hepatic macrophage, placental macrophage, or thymic macrophage, and the biologically active substance produced is a tumoricidal substance or interleukin-1.
Patent EP-0144486-A2 (EP)
Inventor: HOFFMANN HANS RAINER DR
IPC: A61K9/24
Filed: 1984-04-04
Abstract: @ The present invention is related to a pharmaceutical product preferably in medical bandage form, for the controlled release of a therapeutically active agent or several such agents to the skin. The pharmaceutical product of the invention consists of an impermeable backing layer, a particularly composed supersaturated reservoir layer for the therapeutically active agent connected therewith and comprising a polymer matrix wherein the therapeutically active agent is soluble and which is permeable to the active agent, an adhesive layer connected with the reservoir layer and permeable to said adhesive layer and removable therefrom for the use of the pharmaceutical product as transdermal therapeutic system, said reservoir layer for the therapeutically active agent consisting of a multitude of layers wherein the concentration of the therapeutically active agent increases from layer to layer with increasing distance from the adhesive layer, and process for producing such a pharmaceutical product.