baber/WOPTO huggingface dataset:
Patent WO-2021118918-A1 (WO)
Inventor: GILLIES ROBERT J
IPC: A61K49/00
Filed: 2020-12-07
Abstract: Two major treatment strategies employed in fighting non-small cell lung cancer (NSCLC) are tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs). The choice of strategy is based on heterogeneous biomarkers expressed by the lung tumor tissue. A major challenge for molecular testing of these biomarkers is the insufficiency of biopsy specimens from patients with advanced NSCLC. Disclosed herein is a method for predicting a response to immune-checkpoint blockade immunotherapy. The method generally involves imaging the subject with positron emission tomography with 2-deoxy-2-[fluorine-18] fluoro-D-glucose integrated with computed tomography to produce  18 F-FDG PET/CT images of the tumor, analyzing the images using PET, CT, and Kulbek Leibler Divergence statistical (KLD) features or, alternatively using deep leaning such as Neural Networks; generating a radiomic signature from the identified features or Network characteristics; and computing a radiomic score based on the radiomic signature that is predictive of responsiveness to ICIs or TKIs.
Patent WO-2021158282-A1 (WO)
Title: Integrated circuit (ic) packages employing a thermal conductive package substrate with die region split, and related fabrication methods
Inventor: KANG KUIWON
IPC: H01L23/367
Filed: 2020-12-09
Abstract: Integrated circuit (IC) packages employing a thermal conductive semiconductor package substrate with die region split and related fabrication methods are disclosed. The package substrate includes a die split where metal contacts in one or more dielectric layers of the package substrate underneath the IC die(s) are thicker (e.g., in a core die region) than other metal contacts (e.g., in a peripheral die region) in the dielectric layer. This facilitates higher thermal dissipation from the IC die(s) through the thicker metal contacts in the package substrate. Cross-talk shielding of the package substrate may not be sacrificed since thinner metal contacts of the package substrate that carry high speed signaling can be of lesser thickness than the thicker metal contacts that provide higher thermal dissipation. The dielectric layer in the package substrate may also include dielectric materials having different thermal conductivities to further facilitate thermal dissipation and/or desired electrical or mechanical characteristics.
Patent WO-2021126766-A1 (WO)
Title: Flexible crescent for low pressure fuel pump
Inventor: ALSUNDKAR AMOL
IPC: F04C18/08
Filed: 2020-12-14
Abstract: A crescent member is disclosed which is configured to be in constant contact with outer and inner gear teeth to prevent unwanted fluid backflow between the gears. The crescent member may be part of a low-pressure fuel pump system for a diesel engine. In order to reduce heat buildup in the crescent member and gear teeth, the crescent member comprises a gap to allow fluid to flow within the crescent member to absorb and dissipate the heat generated by friction. The crescent member is resilient to maintain constant contact, but flexible enough to reduce wear from friction over time.
Patent WO-2021138241-A1 (WO)
Title: Wireless power devices with capacitive foreign object detection sensors
Inventor: REN SAINING
IPC: H02J50/10
Filed: 2020-12-28
Abstract: A wireless power transmitting device uses a wireless power transmitting coil to transmit wireless power signals to a wireless power receiving device. The wireless power transmitting coil is located in a housing. The housing has a circular outline and contains one or more magnets that couple to corresponding magnets in the wireless power receiving device to help align a wireless power receiving coil in the wireless power receiving device to the wireless power transmitting coil in the wireless power transmitting device. A circular array of capacitive sensor electrodes is supported by the housing at a location that overlaps the wireless power transmitting coil. Capacitive sensor measurements from the capacitive sensor array are analyzed to determine whether a foreign object such as a coin or paperclip is present between the housing and the wireless power receiving device.
Patent WO-2021141851-A1 (WO)
Title: Method and apparatus for signaling skip mode flag
Inventor: XU XIAOZHONG
IPC: H04N19/44
Filed: 2021-01-04
Abstract: Aspects of the disclosure provide methods and apparatuses for video encoding/decoding. In some examples, an apparatus for video decoding includes receiving circuitry and processing circuitry. In some embodiments, processing circuitry decodes, prediction information for a block in an I slice from a coded video bitstream, and determines, whether an intra block copy (IBC) mode is possible for the block in the I slice. In response to a slice type parameter indicating I slice and at least a width or height of the block being greater than 64, the processing circuitry sets a current mode type parameter to MODE_TYPE_INTRA. Further, in an embodiment, the processing circuitry decodes a flag that indicates whether a skip mode is applied on the block from the coded video bitstream. Then, the processing circuitry reconstructs the block at least partially based on the flag.
Patent WO-2021178045-A1 (WO)
Title: Étalonnage du temps de propagation de groupe de dispositifs de rang inférieur assisté par des dispositifs surfacturés pour le positionnement en nr
Inventor: DUAN WEIMIN
IPC: H04L29/08
Filed: 2021-01-08
Abstract: L'invention concerne des techniques d'étalonnage du temps de propagation de groupe pour un UE de rang inférieur en tirant parti de la précision relativement élevée du positionnement par RTT pour un UE surfacturé. Ceci peut permettre un étalonnage en ligne/sur le terrain du temps de propagation de groupe d'UE de rang inférieur, permettant à des UE de rang inférieur d'être étalonnés lorsque c'est nécessaire. Suivant la fonctionnalité souhaitée, les techniques d'étalonnage peuvent inclure l'utilisation de mesures de RTT avec une station de base, ou d'une mesure de RTT entre l'UE de rang inférieur et l'UE surfacturé.
Patent WO-2021150384-A1 (WO)
Title: Reflectarray antenna with two-dimensional beam scanning
Inventor: SHAHVIRDI DIZAJ YEKAN TAHA
IPC: H01Q3/46
Filed: 2021-01-08
Abstract: Examples disclosed herein relate to a reflectarray antenna system with two-dimensional beam scanning that includes a first reflectarray having a polarizing grid that operates as a reflective surface in a first polarization and operates as a transparent surface in a second polarization. The reflectarray antenna system includes a second reflectarray comprising an array of reflectarray cells and arranged parallel to the first reflectarray. The second reflectarray includes a first set of feed elements arranged along a first axis and a second set of feed elements arranged along a second axis orthogonal to the first axis to scan a field of view along the first and second axes. The second reflectarray can radiate radio frequency (RE) beams in the first polarization with the first and second sets of feed elements for reflection at the polarizing grid and radiate reflected RE beams in the second polarization for transmission through the polarizing grid.
Patent WO-2021146370-A1 (WO)
Title: Map4k1 inhibitors
Inventor: BRUBAKER JASON
IPC: A61K31/4725
Filed: 2021-01-14
Abstract: One embodiment of the disclosure is a compound represented by Formula I or a pharmaceutically acceptable salt thereof. The variables in Formula I are defined herein. Compounds of Formula I are selective MAP4K1 inhibitors, which can be used to treat a diseases or disorders in a subject that benefits from control of MAP4K1 activity.
Patent WO-2021146566-A1 (WO)
Title: Engineered fibroblasts as cell therapy to treat cancer via tumor stroma stabilization
Inventor: CHEN YUN
IPC: A61P35/00
Filed: 2021-01-15
Abstract: The disclosure is directed to compositions and methods comprising genetically engineered fibroblasts for inhibiting progression of a cancerous tumor.
Patent WO-2021154981-A1 (WO)
Title: Notary system for a distributed ledger
Inventor: MALENE TUDOR
IPC: G06Q20/02
Filed: 2021-01-28
Abstract: A system is provided for issuing static tokens on a decentralized distributed ledger in which transactions are recorded by parties to the transactions without the use of a blockchain. The system generates an identifier of a token. The system accesses a verification key of the owner of the token. The system generates an issue transaction that outputs the identifier, the verification key, a description of the asset the token represents, and an identification of the issuer. The system adds to the transaction an issuer signature. The system provides the issue transaction to a notary system for notarization. The notary system stores a reference to the output for the token identifier and the verification key. The notary system uses the verification key to determine whether a transfer transaction that inputs the token was signed using the corresponding signing key.
Patent WO-2021155163-A1 (WO)
Title: Plug with a resettable closure member
Inventor: STOLBOUSHKIN EUGENE
IPC: E21B34/14
Filed: 2021-01-29
Abstract: A plug with a resettable closure member comprising a body defining a flow bore, a closure member movable between a position closing the flow bore and a position wherein the flow bore is open, the closure member responsive to a selected hydrodynamic force to move to the position closing the flow bore and responsive to an attractive magnetic force to move to the position wherein the flow bore is open.
Patent WO-2021257125-A1 (WO)
Title: Separate constrained directional enhancement filter
Inventor: DU YIXIN
IPC: H04N19/12
Filed: 2021-02-02
Abstract: A method, a non-transitory computer readable medium, and a computer system is provided for encoding or decoding video data. The method may include: receiving video data comprising a chroma component and a luma component; parsing, deriving or selecting a number of presets for the chroma component in one frame, and a number of presets for the luma component in the one frame; and decoding the video data. The method may further comprise: performing a separate Constrained Directional Enhancement Filter (CDEF) process of filtering luma and chroma components independent from each other based on the number of presets for the chroma component in one frame, and the number of presets for the luma component in the one frame.
Patent WO-2021211193-A1 (WO)
Inventor: XI JINWEN
IPC: G06N3/08
Filed: 2021-02-09
Abstract: L'invention concerne des systèmes et des procédés associés à une optimisation par gradient à double moment avec exigences de mémoire réduites. Un exemple de procédé est décrit dans un système comprenant un optimiseur par gradient et une mémoire configurée pour stocker des valeurs de moment associées à un modèle de réseau de neurones comprenant L couches. Le procédé comprend la récupération, dans la mémoire, d'un premier ensemble de valeurs de moment et d'un deuxième ensemble de valeurs de moment, correspondant à une couche du modèle de réseau de neurones, ayant un format de stockage sélectionné. Le procédé comprend en outre la conversion du premier ensemble de valeurs de moment en un troisième ensemble de valeurs de moment ayant un format d'entraînement associé à l'optimiseur par gradient, et la conversion du deuxième ensemble de valeurs de moment en un quatrième ensemble de valeurs de moment ayant un format d'entraînement associé à l'optimiseur par gradient. Le procédé comprend en outre l'exécution d'une optimisation par gradient à l'aide du troisième ensemble de valeurs de moment et du quatrième ensemble de valeurs de moment.
Patent WO-2021163058-A1 (WO)
Title: Methods of stimulating an anti-tumor response using a selective glucocorticoid receptor modulator
Inventor: GREENSTEIN ANDREW E
IPC: A61K31/4745
Filed: 2021-02-09
Abstract: Methods of improving immune function in a cancer patient having a solid tumor are disclosed. The improvement in immune function may slow or stop tumor growth, and may reduce tumor load. Methods include administering effective amounts of a cancer treatment and a nonsteroidal glucocorticoid receptor modulator (GRM) or selective GRM (SGRM). The cancer treatment may include administration of a checkpoint inhibitor. GRM or SGRM administration may induce checkpoint-inhibitor sensitivity in the cancer. Improved immune function may include increased CD8+ T-cell activation, increased pro-inflammatory cytokine secretion, increased TNFα secretion, increased IFNγ secretion, and other changes as compared to such activation and secretion prior to GRM administration. In embodiments, immune function is improved after 1, 2, 3, or more days of GRM administration. Other patient characteristics may also be improved by the methods disclosed herein. GRMs include heteroaryl-ketone fused azadecalin and octahydro fused azadecalin GRMs. GRM administration includes oral GRM administration.
Patent WO-2021163565-A1 (WO)
Title: Personal proximity alert device and associated behavior modification system
Inventor: SHAW THOMAS
IPC: A61B5/103
Filed: 2021-02-12
Abstract: A personal proximity alert device and associated behavior modification system configured to monitor and/or detect a hand of a user or another person or object penetrating a personal protection zone around the facial area of the user and to alert users to such detected risks and/ or to the presence of others approaching within a predetermined minimum socially safe distance to reduce the likelihood of accidentally transmitting viruses or other pathogens.
Patent WO-2021216233-A1 (WO)
Inventor: FAY GINA
IPC: G05D1/02
Filed: 2021-03-18
Abstract: A method for constraining robot autonomy language includes receiving a navigation command (44) to navigate a robot (10) to a mission destination (46) within an environment (8) of the robot and generating a route specification (200) for navigating the robot from a current location (43) in the environment to the mission destination in the environment. The route specification includes a series of route segments (210). Each route segment in the series of route segments includes a goal region (220) for the corresponding route segment and a constraint region (230) encompassing the goal region. The constraint region establishes boundaries for the robot to remain within while traversing toward the goal region. The route segment also includes an initial path (310) for the robot to follow while traversing the corresponding route segment.
Patent WO-2021207324-A1 (WO)
Title: Feedback for multicast transmissions while in an inactive or idle mode
Inventor: ZHANG XIAOXIA
IPC: H04L1/18
Filed: 2021-04-07
Abstract: Methods, systems, and devices for multicast wireless communications are described. A base station may configure a user equipment (UE) for providing feedback for multicast transmissions from the base station while the UE is in an inactive or idle mode. Based on a configuration sent to the UE from the base station, the UE may determine resources or a timing advance (TA) to use for transmission of a feedback message for multicast communications. A base station may configure a UE with multiple TA commands, each corresponding to a TA value and a set of channel metrics associated with group of cells including a serving cell of the UE. Based on measure channel metrics at the UE, the UE may determine a TA to use for multicast feedback. TA values may be determined using neural network modeling.
Patent WO-2021211387-A1 (WO)
Inventor: GREENSTEIN LARRY
IPC: H01Q1/32
Filed: 2021-04-11
Abstract: A heat dissipation system for an antenna assembly (25) for a vehicle (1100) is disclosed that provides enhanced heat removal attributes and that provides heat transfer from various components (57) to a heat sink (68) through different heat transfer flow paths to reduce the transfer of heat from high heat producing components (57) to heat sensitive components (50). Improved heat insulation components can be added to maximize the thermal isolation between heat producing components and to prevent heat transferred from the vehicle (1100) into the antenna assembly (25).
Patent WO-2021216439-A1 (WO)
Inventor: GULTEKIN HAKAN ROBERT
IPC: G06N20/00
Filed: 2021-04-19
Abstract: Embodiments of the present invention train multiple Perception models to predict contextual metadata (tags) with respect to target content items. By extracting context from content items, and generating associations among the Perception models, individual Perceptions trigger one another based on the extracted context to generate a more robust set of contextual metadata. A Perception Identifier predicts core tags that make coarse distinctions among content items at relatively higher levels of abstraction, while also triggering other Perception models to predict additional perception tags at lower levels of abstraction. A Dense Classifier identifies sub-content items at various levels of abstraction, and facilitates the iterative generation of additional dense tags across integrated Perceptions. Class-specific thresholds are generated with respect to individual classes of each Perception to address the inherent sampling bias that results from the varying number and quality of training samples (across different classes of content items) available to train each Perception.
Patent WO-2021222475-A1 (WO)
Inventor: ATHERTON HUNTER
IPC: B63B79/30
Filed: 2021-04-28
Abstract: A portable sensing device may be deployed for determining at least one stability metric of a vessel. The sensing device may include one or more motion sensors for sensing motion of the vessel, one or more freeboard sensors for determining a freeboard of the vessel, and a computing system for processing motion data from the one or more motion sensors and freeboard data from the one or more freeboard sensors to determine the at least one stability metric. The computing system may be programmed to transform the motion data from time domain motion data to frequency domain motion data and process the frequency domain motion data to determine the at least one stability metric of the vessel and the freeboard of the vessel.
Patent WO-2021226003-A1 (WO)
Title: Il4i1 inhibitors and methods of use
Inventor: CASH BRANDON
IPC: C07D409/14
Filed: 2021-05-04
Abstract: Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as IL4I1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for IL4I1-related diseases.
Patent WO-2021231179-A1 (WO)
Title: System, method and user interface for supporting scheduled mode changes on electronic devices
Inventor: CROWLEY MATTHEW
IPC: G06F3/0484
Filed: 2021-05-06
Abstract: An electronic device displays a respective user interface corresponding to a restricted state. Displaying a first user interface that corresponds to the restricted state when a current time is outside a first preset time period, and displaying a second user interface that corresponds to the restricted state when the current time is within the first preset time period. While displaying the respective user interface, detecting a first input. In response to detecting the first input that meets first criteria, directed to the first user interface, replacing display of the first user interface with a third user interface different from the first and second user interfaces. In response to detecting the first input that meets second criteria different from the first criteria, directed to the second user interface, replacing display of the second user interface with display of the first user interface.
Patent WO-2022086603-A1 (WO)
Title: Chiffrement de dispositif de stockage de données
Inventor: KLAPMAN MATTHEW
IPC: G06F21/62
Filed: 2021-06-21
Abstract: La présente invention concerne un matériel de dispositif de stockage de données (DSD) et, plus spécifiquement, des systèmes et des procédés pour chiffrer des données stockées sur un DSD. Un DSD comprend un support de stockage non volatil pour stocker de multiples objets de données de système de fichier à l'aide d'un adressage de blocs. Un dispositif de commande de dispositif est intégré au DSD et comprend une circuiterie matérielle configurée pour chiffrer des données à stocker sur le support de stockage. Le dispositif de commande reçoit une demande pour un objet de données de système de fichier chiffré à partir d'un système informatique hôte, identifie l'une des plages de blocs où l'objet de données de système de fichier chiffré demandé est stocké sur le support de stockage, et envoie l'objet de données de système de fichier stocké dans la plage identifiée de blocs au système informatique hôte sous une forme chiffrée telle que stockée sur le support de stockage.
Patent WO-2022015495-A1 (WO)
Title: Dynamic configuration trace capture technique
Inventor: RENIE DAVID MICHAEL
IPC: G06F11/34
Filed: 2021-06-29
Abstract: A dynamic configuration trace capture technique enables software developers to monitor, diagnose and solve errors associated with application development and production. A client library of an investigative platform is loaded in a user application and interacts with an agent process to instrument executable code of the user application. A dynamic configuration specifies information, such as methods and associated arguments, variables and data (values), to instrument. The client library may re-load the dynamic configuration at the capture points, which may change the frequency of tracing a method and its associated information. The dynamic configuration may be defined per method, argument, variable, and/or data structure. The dynamic configuration may be initially deployed with default heuristics defined in the client library. The technique enables optional overrides, either by manual provision of adjustments by a user via a user interface infrastructure of the investigative platform, or as specified by the agent after retrieving a configuration file, an environment variable, etc. from a configuration service.
Patent WO-2023277927-A1 (WO)
Title: Media stacker
Inventor: VANDENBERGH KURT ANNETE M
IPC: B65H29/14
Filed: 2021-07-02
Abstract: A media stacker may comprises a stacking platform; and a pair of a guiding tracks above the stacking platform and extending from a media receiving side of the media stacker in a media advance direction along opposite sides of a media transport path; wherein at least one guiding track of the pair of guiding tracks is movable between a support position and a release position to guide and support the media sheet above the stacking platform and to release the media sheet to drop from the guiding track to the stacking platform.
Patent WO-2022016066-A1 (WO)
Title: Commissure assemblies formed from tabs of asymmetric leaflets
Inventor: Nir Noam
IPC: A61F2/24
Filed: 2021-07-16
Abstract: The present invention is directed toward prosthetic heart valves that include an expandable frame and a leaflet assembly mounted therein, wherein the leaflet assembly is coupled to the frame via a plurality of commissure assemblies, formed from tabs of adjacent asymmetrical leaflets secured to each other, wherein at least one of the leaflet tabs includes a vertical tab portion folded over the tab of an adjacent leaflet.