baber/WOPTO huggingface dataset:
Patent CA-2403110-C (CA)
Title: Derives de n-desacetylthiocolchicine et compositions renfermant ces derives
Inventor: BOMBARDELLI EZIO
IPC: A61K31/165
Filed: 2001-03-12
Granted: 2009-12-15
Abstract: L'invention concerne des dérivés de N-désacétyl- thiocolchicine ou de l'isostère de ce dernier, représentés par la formule (I), dans laquelle n représente un entier compris entre 0 et 8, Y représente un groupe CH2 ou, lorsque n représente 1, un groupe représenté par la formule NH. Ces composés (I) ont une activité anti-proliférative.
Patent CA-2411716-C (CA)
Inventor: GALLEY GUIDO
IPC: A61K31/445
Filed: 2001-06-01
Granted: 2010-06-22
Abstract: The invention relates to compounds of the formula (I) wherein R1 is hydrogen, lower alkyl, lower alkenyl, phenyl or the following groups -(CH2)m-non aromatic heterocyclyl, which is optionally substituted by lower alkyl, or is -(CH2)m-heteroaryl, which is optionally substituted by one or two substituents selected from the group consisting of lower alkyl, lower alkoxy, holgen, CF3, benzyl or cyano, or is -(CH2)m-C(O)-NRR', -(CH2)m-C(O)-lower alkyl, -(CH2)m-C(O)-O-lower alkyl, -(CH2)m-O-lower alkyl, -(CH2)m-CH[C(O)-O-lower alkyl]2, -(CH2)m-CH(OH)-CH2-O-phenyl, -(CH2)m-CH(CF3)OH, -(CH2)m-OH, -(CH2)m-CN, -(CH2)m-NRR', -(CH2)m-cycloalkyl or -(CH2)m-CHF2; R2 is hydrogen, lower alkyl, halogen or lower alkoxy; R3 is lower alkyl, lower alkoxy, halogen or CF3; R,R' are the same or different and are hydrogen or lower alkyl; X is > N-, > C = or > CH-;  X1/X2 are independently from each other hydrogen, hydroxy or lower alkoxy or may be together an oxo group; Y1/Y2 are independently from each other hydrogen, lower alkyl, -(CH2)m-phenyl or may be together an oxo group; Z is a bond, -CH2- or -C(O)-; m is 0, 1, 2, 3 or 4; n is 2 or 3; n' 0, 1 or 2; and pharmaceutically acceptable acid addition salts thereof. The described compounds have a good affinity to the NK1 receptor.
Patent CA-2411957-C (CA)
Inventor: THOMSON NICHOLAS MURRAY
IPC: C07D295/22
Filed: 2001-06-07
Granted: 2007-09-18
Abstract: There is provided a process for the production of a compound of general formula (I), wherein A, R1, R2, R3 and R4 have meanings given in the description, which process comprises the dehydrogenation of a compound of general formula (II).
Patent CA-2414202-C (CA)
Inventor: VAN DEN BERG MICHEL
IPC: C07C67/303
Filed: 2001-07-06
Granted: 2010-03-23
Abstract: Catalyst for the asymmetric (transfer) hydrogenation represented by the formula MLaXbSc, where M is a transition metal, to be chosen from rhodium and ruthenium, and X is a counter ion and S is a ligand, a ranges from 0.5 to 3 and b anc c, each independently, range from 0 to 2, and L is a chiral ligand having the formula (1), where Cn together with the two 2 O-atoms and the P-atom forms a substituted or non-substituted ring with 2-4 C-atoms, R1 and R2 each independently represent H, an optionally substituted alkyl, aryl, alkaryl or aralkyl group or may form a (heterocyclic) ring together with the N-atom to which they are bound. And a process for the asymmetric (transfer) hydrogenation of an olefinically unsaturated compound, ketone, imine or oxime derivate in the presence of a hydrogen donor and of a catalyst, use being made of a catalyst represented by formula MLaXbSc, where M is a transition metal, to be chosen from rhodium, iridium and ruthenium, X I a counter ion, S is a ligand, a ranges from 0.5 to 3 and b and c range from 0 to 2, and L is a chiral ligand having the formula (1), where Cn together with the two 2 O-atoms and the P-atom forms a substituted or non-substituted ring with 2-4 C-atoms;  and R1 and R2 are as defined above.
Patent CA-2419038-C (CA)
Inventor: SUGIMOTO MANABU
IPC: C12N15/82
Filed: 2001-08-10
Granted: 2011-12-20
Abstract: Acides nucléiques et protéines présentant un niveau d'expression augmenté sous l'effet du stress provoqué par le sel et comprenant un acide nucléique possédant une séquence représentée par SEQ ID NO:1 de la liste des séquences et leurs variantes, et une protéine possédant la séquence d'acides aminés représentée par SEQ ID NO:2 de la liste des séquences et leurs variantes. Ces acides nucléiques et ces protéines permettent d'obtenir une nouvelle protéine dont le niveau d'expression est augmenté sous l'effet du stress provoqué par le sel et qui est capable de conférer une tolérance au stress provoqué par le sel à des plantes, ainsi qu'un nouveau gène codant cette protéine.
Patent CA-2421788-C (CA)
Title: Regeneration of program clock reference data for mpeg transport streams
Inventor: NEMIROFF ROBERT S
IPC: H04N7/26
Filed: 2001-08-31
Granted: 2011-05-03
Abstract: A system for providing an accurate time reference for multiple input and output digital video signals of a transcoder (100) that is particularly suited for use with MPEG data. The multiple streams are synchronized with a single master system time clock (155) at the transcoder (100). Timing data from the master clock is compared to timing data from packets that are input to the transcoder to determine an offset (120, 130). In particular, timing data, such as a program clock reference (PCR) field, is recovered from packets (104) of different channels that are input to the transcoder (122, 132). For each channel, timing data is then provided for packets (106) that are output from the transcoder based on the offset and timing data of the master clock (155) at the respective output times. In particular, the adjusted timing data is determined as a sum of the offset and an associated hardware error, less a delay (PcrSysDla) associated with the transcoder, which includes a lookahead delay and a buffer delay. The associated hardware error represents an error of the master clock and/or a system time clock of an encoder that encoded the particular channel.
Patent CA-2425542-C (CA)
Title: Methods for raising pre-adult anadromous fish
Inventor: NEARING JACQUELINE
IPC: A23K1/18
Filed: 2001-10-11
Granted: 2005-07-05
Abstract: The invention relates to methods, compositions and kits for improving the raising of pre-adult anadromous fish, or preparing pre-adult anadromous fish for transfer to seawater. The methods involve adding at least one Polyvalent Cation Sensing Receptor (PVCR) modulator to the freshwater in an amount sufficient to increase expression and/or sensitivity of at least one PVCR; and adding feed for fish consumption to the freshwater, wherein the feed comprises an amount of NaC1 sufficient to contribute to a significantly increased level of the PVCR modulator in serum of the pre-adult anadromous fish.
Patent CA-2439255-C (CA)
Inventor: REDDY E PREMKUMAR
IPC: C07D277/52
Filed: 2002-02-28
Granted: 2011-01-04
Abstract: N-(Aryl)-2-aryléthenesulfonamides et sels pharmaceutiquement acceptables et leurs compositions, utilisés comme agents antiprolifératifs, y compris, par exemple, des antigènes anticancéreux. Ils sont aussi utiles en tant qu'agents radioprotecteurs.
Patent CA-2442196-C (CA)
Inventor: CHUNG PEI-CHIANG
IPC: E04H12/04
Filed: 2003-09-23
Granted: 2007-07-03
Abstract: A wooden newel post includes upper newel and lower newel post sections, and a decorative lamella layer.      The upper newel post section is made of higher quality wood, and has a lower post connecting end. The higher quality wood is selected from the group consisting of oak wood and maple wood. The lower newel post section is made of lower quality wood, and has an upper post connecting end connected to the lower post connecting end of the upper newel post section, and an outer newel post surface. The lower quality wood is selected from the group consisting of rubber wood and pine wood from plantation forests, defective higher quality wood, and high density fiber material. The decorative lamella layer is made of higher quality woad, and is secured to the outer newel post surface of the lower newel post section.
Patent CA-2453335-C (CA)
Inventor: JOHANSON JERRY R
IPC: D21C7/06
Filed: 1998-08-28
Granted: 2005-10-11
Abstract: A comminuted cellulosic fibrous material treatment vessel assembly includes a substantially vertical vessel having a tap, bottom, and outlet, and through which the material flows in a flow direction. The vessel preferably has a substantially cylindrical wall with at least one diameter-changing transition between the inlet and the outlet. A screen assembly is preferably provided at or just past the transition. The screen assembly comprises one or more annular screen surfaces diverging in the flow direction of the material, the angle of divergence being between about 0.5-10° to the vertical, and preferably substantially continuous.      Providing such a screen assembly reduces the radial compression of material thereon, and increases the volume and rate of liquid that can flow through the material and be removed through the screen surface compared to a non-diverging screen surface that is a right-cylindrical surface). The screen surface has openings of substantially uniform size, and preferably with a substantially uniform percentage of open area, in the flow path.
Patent CA-2456093-C (CA)
Title: Procede de fabrication d'un compose de pyridine
Inventor: TOHYAMA YOSHITOMO
IPC: C07D401/12
Filed: 2002-07-31
Granted: 2009-11-10
Abstract: Procédé de fabrication d'un composé de pyridine [d] [d] (dans laquelle R<3> représente halogéno, cyano ou nitro et R<4> représente hydrogéno ou halogéno) possédant une excellente activité herbicide qui consiste à faire réagir un composé de pyridine [a] [a] (dans laquelle R<1> représente alcoxy C1-6 et R<3 >et R<4> ont les valeurs définies plus haut) avec un composé d'ester alpha -diazo [f] N2CHCOR<1> [f] (dans laquelle R<1> a la valeur définie plus haut) en présence d'un acide.
Patent CA-2459867-C (CA)
Inventor: ABRAMS ANDREW L
IPC: A61M15/00
Filed: 2002-09-06
Granted: 2012-03-13
Abstract: A child-sized adaptor for a DPI or MDI is provided. Also provided is a patient feedback mechanism for signaling and/or teaching proper inhaler use.
Patent CA-2467848-C (CA)
Title: Installation de triage permettant de trier des articles alimentes en vrac
Inventor: CHRISTENSEN KENT
IPC: B07C1/06
Filed: 2002-10-28
Granted: 2008-06-03
Abstract: L'invention concerne la fabrication de briques de pavage coulées (4), constituées de béton, à forme de base rectangulaire. Parfois, un traitement de finissage des briques est mis en oeuvre par  </=  tonnelage  >/= , les briques différemment organisées sur des palettes ou sur une planche de coulage sont transférées vers un tambour où elles sont polies au tonneau dans le but d'obtenir une surface présentant un aspect particulier. Pour des raisons économiques, on préfère distribuer les briques tonnelées en vrac, étant donné qu'une palettisation manuelle ultérieure constitue un élément relativement onéreux. L'invention concerne donc une unité de triage (2) comprenant un convoyeur (6) qui présente un convoyeur à bande (8) sur la surface duquel, entre une zone de réception (14) des briques (4) et une zone de distribution (16), sont présentes des barres de guidage (20) mutuellement espacées, placées de manière oblique, relativement au sens de déplacement (F) du convoyeur, les briques (4) étant guidées en rang selon la même orientation pour une palettisation ultérieure par une machine.
Patent CA-2468158-C (CA)
Title: System and method for the production of biogas and compost
Inventor: FORRESTAL BRIAN JOSEPH
IPC: C05F17/00
Filed: 2004-05-25
Granted: 2006-05-23
Abstract: A system and method for continuous decomposition of organic material to produce biogas and compost in which successive reactor zones in a primary reactor are used in turn to receive organic material which is decomposed in situ anaerobically followed by aerobic decomposition and excavation of raw compost from the same reactor zone where it is received into the organic treatment facility. Organic rich liquor recovered during anaerobic decomposition is further decomposed in a secondary reactor from which spent liquor is returned to the primary reactor while biogas harnessed from both the primary and secondary reactors is treated, and optionally used to fuel the operation of the organic treatment facility or for sale as fuel or electricity.
Patent CA-2470480-C (CA)
Title: Indolinone derivatives useful as protein kinase inhibitors
Inventor: GRIFFIN JOHN H
IPC: A61K31/437
Filed: 2002-12-20
Granted: 2010-12-14
Abstract: in which R1, R2, R3 and R4 have the meanings given in the specification, are receptor tyrosine kinase inhibitors useful in the treatment of proliferative disorders, such as cancer.
Patent CA-2470575-C (CA)
Inventor: SCHLIENGER NATHALIE
IPC: C07D209/00
Filed: 2002-12-23
Granted: 2011-02-22
Abstract: L'invention concerne des composés spiroazacycliques utilisés comme modulateurs du récepteur de monoamine ; des compositions renfermant lesdits composés ; des procédés d'inhibition d'une activité d'un récepteur de monoamine avec lesdits composés ; des procédés de traitement d'un état pathologique associé à un récepteur de monoamine au moyen desdits composés ; ainsi que des procédés d'identification d'un sujet convenant pour le traitement au moyen desdits composés.
Patent CA-2476430-C (CA)
Title: Sodium channel blockers
Inventor: JOHNSON MICHAEL R
IPC: A61P1/04
Filed: 2003-02-19
Granted: 2011-11-08
Abstract: The invention is directed to sodium channel blockers consisting of pyrazinoylguanidine compounds of the formula (I): (see formula I) These compounds give a prolonged pharmacodynamic half-life on mucosal surfaces and make them particularly useful for treating cardiovascular disease.
Patent CA-2478497-C (CA)
Inventor: CARMICHAEL ROBERT P
IPC: A61C8/00
Filed: 2003-02-27
Granted: 2010-12-14
Abstract: In accordance with the invention, a dental implant comprises a body portion and a head portion. The body portion includes a tip portion which is remote from the head portion, a lead thread portion adjacent the tip portion, an intermediate thread portion adjacent the lead thread portion and a distal thread portion which is adjacent to the head portion. The dental implant further includes a central bore within the head portion. There is a thread within the bore for receiving a dental prosthesis. The tip portion comprises at least one cutting edge for cutting bone as the implant is rotated. The body portion includes at least one flute. The flute has a first end adjacent to the at least one cutting edge. for assisting removal of bone cuttings from the cutting edge. In a more preferred embodiment of the invention, the implant includes at least two cutting edges and at least two flutes. In a particularly preferred embodiment, the flutes extend distally toward the head portion, but terminate at the end of the intermediate portion so that the distal thread portion does not have any portion thereof containing a fluted surface.
Patent CA-2479326-C (CA)
Title: Dual zone feedwell for a thickener
Inventor: TAYLOR DAVID JOHN BUCHANAN
IPC: B01D21/24
Filed: 2003-03-11
Granted: 2012-01-10
Abstract: The invention provides an extraction device (1) for liquid suspensions and pulps and is designed for use in the field of mineral processing. The extraction device includes two adjacent upstream and downstream concentric chambers (2) and (3) defining a feedwell (4). The feedwell is centrally located upstream of a third chamber in the form of a thickening tank (5). All three chambers are in sequential unidirectional fluid flow relationship such that feed liquid flows firstly from chamber (2) to chamber (3) and then to the tank (5).
Patent CA-2480394-C (CA)
Inventor: HARTLAUB CHARLES
IPC: F01L21/00
Filed: 2003-02-28
Granted: 2008-10-07
Abstract: A pneumatic motor (10) is provided that includes an intake chamber (22) in fluid communication with at least one intake channel (28). Each intake channel (28) is in fluid communication with a corresponding cylinder (20), which receives a piston (12) that cycles upwardly and downwardly to rotate a motor axle. A member (30) is placed in each intake channel (28) to seal the corresponding cylinder (20) from each intake channel (28) when compressed fluid in the intake channel (28) has a higher pressure then pressure in the corresponding cylinder (20). An actuator (34) extends downwardly from each piston (12) and has a profile that, during a portion of the upward cycle of the piston (12), causes the actuator (34) to push the member (30) back into each intake channel (28) to allow compressed fluid into each of the corresponding cylinders (20). Exhaust grooves (38) are defined on sections (36) such that during the downward cycle of the piston (12) a seal is broken allowing compressed fluid in the cylinder (20) to bypass the piston (12) an escape through a vent above each cylinder (20).
Patent CA-2480618-C (CA)
Title: Improved lng carrier
Inventor: NIERENBERG ALAN B
IPC: F17C1/00
Filed: 2002-03-29
Granted: 2007-09-18
Abstract: An improvement to an LNG carrier having a vaporizer (23) on board said LNG carrier for vaporizing the LNG to a gaseous state is disclosed. The LNG carrier includes a source of heat (21) for said vaporizer; an intermediate fluid circulating between said vaporizer and said source of heat; and one or more pumps (4) for circulating said intermediate fluid between said vaporizer and said source of heat. The improvement includes equipment connections for adding at least one additional source of heat (26) for said vaporizer, pre-installed flow conduits between said vaporizer and equipment connections, and valves for isolating said pre-installed flow conduits from said vaporizer.
Patent CA-2481191-C (CA)
Title: Elevateur de mise en place de truie dans une cage de mise a bas
Inventor: KLEINSASSER JONATHAN
IPC: A01K1/02
Filed: 2003-06-02
Granted: 2008-01-22
Abstract: La présente concerne une cage de mise bas qui comprend une fosse et sur la fosse une première partie de plancher sur laquelle la truie peut se tenir et se coucher et deux autres parties de plancher de chaque côté de la première partie de plancher pour recevoir les porcelets et des parois de confinement pour confiner la truie sur la première partie de plancher, et un dispositif de levage est prévu pour soulever la truie afin d'éviter qu'elle n'écrase les porcelets. L'appareil comprend une base portée au-dessus de la fosse sur un berceau et un mécanisme de levage à sac de gaz porté sur la base au-dessus du fumier et agencé de manière à soulever une plaque portant deux rails parallèles soutenant la première partie de plancher. Une soupape pneumatique s'étend à travers le revêtement de sol et est actionnée par la pression de contact exercée par la truie pour actionner la commande d'écoulement de l'air. La vitesse de montée est supérieure à la vitesse d'abaissement. Un agencement de levier en ciseaux monté sur la base au-dessus la fosse sert à soutenir et à guider le plancher sur le sac.
Patent CA-2485151-C (CA)
Inventor: TSAI KEH-CHYUAN
IPC: E04H9/02
Filed: 2004-10-14
Granted: 2012-08-14
Abstract: Élément porteur fonctionnel parasismique et dispersif d'énergie, qui comprend une structure principale munie de deux éléments de structure espacés l'un de l'autre, un panneau mural de contreventement relié entre les deux éléments de structure, et au moins un élément de renfort se prolongeant à travers le panneau mural de contreventement pour restreindre ledit panneau mural sur le plan latéral.
Patent CA-2487964-C (CA)
Title: Oxidation of nox's with sodium chlorite in combination with a thermal nox removal process
Inventor: TAKACS THERESA J
IPC: B01D53/56
Filed: 2003-05-09
Granted: 2010-09-28
Abstract: A process for reducing NOX concentrations in waste gas streams by contacting the waste gas stream with a reducing agent selected from ammonia and urea and then oxidizing the lower NOX's present in the waste gas streams to higher oxides with sodium chlorite.
Patent CA-2494570-C (CA)
Title: Seed-specific gene promoters and uses thereof
Inventor: TAKAIWA FUMIO
IPC: C12N5/10
Filed: 2004-10-29
Granted: 2010-10-19
Abstract: An objective of the present invention is to provide promoters comprising seed-specific promoter activity, and methods of expressing foreign proteins in seeds. The present inventors isolated the promoters of a number of genes that are expressed in rice seeds, constructed binary vectors in which each promoter is inserted upstream of the GUS reporter gene, and transformed rice using the Agrobacterium method. The inventors then used GUS expression level as an index to examine the site of expression, the expression pattern during seed maturation, and the level of expression in seeds for each promoter. They thus discovered promoters with activity specific to a particular site in seeds, and with higher activity than constitutive promoters and known seed-specific promoters.
Patent CA-2500192-C (CA)
Title: Diamond tool
Inventor: KIM SOO-KWANG
IPC: C22C26/00
Filed: 2004-08-10
Granted: 2008-07-15
Abstract: The diamond tool comprises a plurality of segments, each of the segments having a single plate-shaped layer or a plurality of plate-shaped layers of diamond particles arranged thereon. The diamond particles are arranged at a predetermined tilt angle to a line connecting upper vertices or a line connecting lower vertices of a cross section, cut parallel in a cutting direction and perpendicular to a cutting surface, so that the diamond particles are protruded and uniformly spaced from each other on the cutting surface of the segment during the cutting operation on the workpiece.
Patent CA-2505179-C (CA)
Inventor: RAO DHARMARAJ RAMACHANDRA
IPC: C07D277/82
Filed: 2003-11-03
Granted: 2012-10-16
Abstract: L'invention concerne la production de 2,6-diamino-4,5,6,7-tétrahydro-benzothiazole utile à la production de pramipexole consistant : (i) à faire réagir du brome avec une solution de 4-acétamido-cyclohexanone dans de l'eau pour produire 2-bromo-4-acétamido-cyclohexanone; (ii) après l'étape (i), à ajouter de la thiourée pour produire 6-acétyle amino-2-amino-4,5,6,7-tétrahydro-benzthiazole; (iii) après l'étape (ii), à ajouter une solution aqueuse d'acide bromhydrique pour produire 2,6-diamino-4,5,6,7-tétrahydro-benzthiazole dihydrobromure; et (iv) après l'étape (iii), à isoler 2,6-diamino-4,5,6,7-tétrahydro-benzthiazole.
Patent CA-2510596-C (CA)
Title: Lignee de cellules dendritiques gen2.2
Inventor: PLUMAS JOEL
IPC: A61K35/14
Filed: 2003-12-16
Granted: 2011-09-20
Abstract: La présente invention concerne des lignées de cellules dendritiques plasmacytoïdes (pDC) humaines, les procédés d'obtention et de culture de ces cellules. Plus particulièrement, l'invention a pour objet une lignée de cellules dendritiques plasmacytoïdes humaines dénommée GEN2.2 déposée à la CNCM sous le numéro CNCM 1-2938. L'invention se rapporte également aux utilisations de ces cellules et à des compositions pharmaceutiques comprenant ces cellules dendritiques plasmacytoïdes (pDC) humaines.
Patent CA-2515035-C (CA)
Title: Dispositif d'interruption de circuit et systeme utilisant un mecanisme de contact a pont et un mecanisme de blocage de reinitialisation
Inventor: GERMAIN FRANTZ
IPC: H02H3/16
Filed: 2004-01-30
Granted: 2013-11-26
Abstract: L'invention concerne un dispositif disjoncteur de fuite de terre (GFCI) qui présente une protection contre le câblage inverse selon laquelle il n'y a pas de courant au niveau des bornes de face même si le câblage du dispositif est inversé. Ce dispositif comprend une paire de ponts mobiles reliés à leurs bornes. La paire de ponts de bornes établit un contact avec les bornes de charge et de face et permet de fournir du courant aux bornes lorsque le dispositif est réinitialisé. Ledit dispositif comprend également un mécanisme de blocage de réinitialisation qui empêche le dispositif d'être réinitialisé après avoir été activé si la partie d'interruption de circuit du dispositif n'est pas opérationnelle.