baber/WOPTO huggingface dataset:
Patent NZ-574533-A (NZ)
Title: Pyrazolo[3,4-b]pyridine compounds, and their use as pde4 inhibitors
Inventor: ALLEN DAVID GEORGE
IPC: A61K31/437
Filed: 2007-07-31
Abstract: Disclosed here in are Pyrazolo[3,4-b]pyridine compounds of formula (I), wherein Ar is given by sub formula (x) and the other substituents are as defined within the spec, salts thereof, processes for their preparation, intermediates usable in the processes and pharmaceutical compositions containing said compounds or salts; in particular N-{[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-yl]methyl}-4-({8-[(2-hydroxyethyl)(methyl)amino]octanoyl}amino)benzamide, its hydrochloride, monohydrochloride and dihydrochloride salt thereof. Such compounds are useful as phosphodiesterase type IV (PDE4) inhibitors and for the treatment and/or prophylaxis of inflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma or rhinitis (e.g. allergic and/or non-allergic rhinitis).
Patent NZ-583241-A (NZ)
Title: A fruit or vegetable beverage with plant sterol and a method for preparation thereof
Inventor: KOPONEN LEENA
IPC: A23L33/00
Filed: 2008-07-24
Abstract: A beverage that has improved stability and comprises a texture component and a plant sterol or plant stanol in an amount of 0.2 to 25 percent by weight of the beverage. The texture component is selected from unhomogenised vegetable puree, fruit pulp and fruit puree. The beverage can further comprise unhomogenised vegetable or fruit juice and homogenised vegetable or fruit material. The beverage can be prepared by a method that comprises mixing an aqueous emulsion containing the plant sterol or stanol with the texture component. The vegetable can be carrot, maize, celery, beets, parsley, cabbage, lettuce, spinach, wheat grass or sauerkraut. The fruit can be orange, apple, pomegranate, go goji, grapefruit, lemon, lime, pineapple, mango, banana, peach, grape, pear, kiwi, cherry, acerola, watermelon, cantaloupe, strawberry, raspberry, cranberry, blueberry, blackcurrant, plum, papya, guava, tomato, cucumber, pea or pumpkin.
Patent NZ-587607-A (NZ)
Title: Elastomer dispersion comprising a dispersed elastomer and accelerator in an aqueous phase and latex materials produced therefrom
Inventor: WANG SHIPING
IPC: C08J3/20
Filed: 2009-03-13
Abstract: Disclosed is an aqueous elastomer dispersion, articles produced from the elastomer dispersion and a compounded latex, comprising a dispersed phase comprising an elastomer and an accelerator, wherein said dispersed phase is formed by dissolving the elastomer and accelerator in a solvent system; and an aqueous phase. Also disclosed is a method of preparing the aqueous elastomer dispersion, comprising the steps of: preparing an elastomer/accelerator solution comprising an elastomer, an accelerator, and a solvent system; emulsifying the elastomer/accelerator solution to form an emulsion; concentrating the emulsion to form a concentrated emulsion; removing substantially all of the solvent system from the concentrated emulsion to form a substantially solvent-free dispersion; and optionally concentrating the substantially solvent-free dispersion.
Patent NZ-588616-A (NZ)
Title: An apparatus for separating a protein of interest comprising a purification system integrated with a particle removal system
Inventor: VOGEL JENS
IPC: A61K38/00
Filed: 2005-09-30
Abstract: Disclosed is an apparatus for separating a protein of interest from a heterogeneous tissue culture fluid mixture. The apparatus comprises a continuous perfusion fermentation system, a continuous particle removal system and a continuous purification system. The continuous particle removal system is integrated with the perfusion fermentation system. The continuous purification system is integrated with the particle removal system. The apparatus is maintained under sterile conditions.
Patent NZ-591292-A (NZ)
Title: Improved cell composition and methods of making the same
Inventor: ZEITLIN ANDY
IPC: A01N1/02
Filed: 2009-08-20
Abstract: Disclosed is a method of making a composition comprising cells, comprising: (a) contacting said cells with a solution comprising dextran and human serum albumin (HSA) to form a cell-containing solution; (b) filtering the cell-containing solution; (c) if said cell-containing solution comprises greater than 10 ± 3 x 106 cells per milliliter, diluting said cells to no more than 10 ± 3 x 106 cells per milliliter with a first dilution solution comprising dextran; and (d) optionally diluting the cell-containing solution with a second dilution solution comprising dextran but not comprising HSA, thereby making a composition comprising cells.
Patent NZ-591411-A (NZ)
Title: Process for producing titanium tetrachloride using low-grade titanium raw materials
Inventor: LU PING
IPC: C01G23/02
Filed: 2008-12-19
Abstract: Disclosed is a method for producing titanium tetrachloride, TiCl4, by using a low grade titanium material, characterized by comprising the following steps: a. adding the low grade titanium material to a furnace, and heating to start up the furnace; b. continuing adding the low grade titanium material when the furnace is heated to 420 degrees, plus or minus 40 degrees, and introducing chlorine with the volume concentration of 75 per cent to 85 per cent for reaction based on reaction rate according to titanium carbide, TiC, content of the low grade titanium material; c. controlling temperature of the furnace at 610 to 650 degrees as the temperature in the furnace rises slowly after the reaction starts; d. collecting titanium tetrachloride-containing gas generated during the reaction for condensation treatment to obtain liquid titanium tetrachloride and tail gas, and taking out reacted inert chloride residue based on the volume of the material added; and e. treating and discharging the remaining residue after the reaction.
Patent NZ-593567-A (NZ)
Title: Method and apparatus for producing a product by micro-gelling and/or micro-particulating a preparation containing whey proteins
Inventor: BURGER MARTIN
IPC: A23J3/08
Filed: 2009-12-21
Abstract: 593567 Disclosed is a method for producing a product by micro-gelling and/or micro-particulating a batch (4) containing whey proteins and an apparatus for carrying out the method. The method comprises the following steps: - providing the batch (4), preferably in a tank (3), - feeding the batch (4) into a dispersing device (7), wherein in the dispersing device (7) shearing forces are continuously generated by way of a revolving rotor engaging in a stator, - direct vapour heating (20) the product, preferably by means of direct vapour heating (20) at the dispersing device (7), preferably to a temperature between 60 and 100 degrees Celsius, and - draining the micro-gelled and micro-particulated product from the dispersing device (7).
Patent NZ-594563-A (NZ)
Title: Aspirated wound dressing
Inventor: TSAI MINGLIANG LAWRENCE
IPC: A61F13/00
Filed: 2010-01-12
Abstract: 954563 A wound dressing (14) for an aspirated wound dressing system (10) is disclosed. The dressing has a wound interface region for contacting or facing a wound site (18), an aspiration port (22) for receiving suction for aspiration of wound exudate and a liquid permeable pressure barrier (24) disposed between the wound interface region and the aspiration port. The pressure barrier substantially prevents the application of negative pressure from the aspiration port to the wound interface region. There is at least one atmospheric vent (28) for equalizing with atmosphere the pressure at the wound interface region and a liquid sensor (30) for sensing liquid within the wound dressing for controlling application of suction by the aspiration unit. The sensor generates a signal that controls the operation of the aspiration unit (12) attached to the aspiration port so that the wound is only exposed to a negative pressure when there is liquid to collect.
Patent NZ-599230-A (NZ)
Title: Coating material for hand application
Inventor: TANIHARA DAISUKE
IPC: C09D175/08
Filed: 2010-10-07
Abstract: Disclosed is a coating agent for hand painting application comprising a urethane resin composition obtainable by reacting the following main agent (A) and curing agent (B), wherein the main agent (A) containing: an isocyanate group-terminated prepolymer (b) having diphenylmethane diisocyanate bound to the termini of a polyol component (a) containing a long chain polyol (e) which contains at least a polyhydroxy functional product such as a trihydroxy or higher-hydroxy functional product and has a molecular weight of 200 or greater and a short chain polyol (d) having a molecular weight of less than 200, and unbound diphenylmethane diisocyanate (c); and wherein the curing agent (B) containing: a crosslinking agent (g) obtained by a short chain polyol (f) having a molecular weight of less than 200, and a long chain polyol (h) having a molecular weight of 200 or greater.
Patent NZ-600921-A (NZ)
Title: Intraocular drug delivery systems
Inventor: ROBINSON MICHAEL R
IPC: A61F2/14
Filed: 2007-11-09
Abstract: Disclosed is a biocompatible, injectable intraocular drug delivery system comprising: (a) a plurality of microspheres with an average diameter between about 8 microns and about 14 microns, and (b) an aqueous vehicle for the microspheres, wherein the microspheres consist essentially of: (1) a therapeutic agent which is estradiol or 2-methoxyestradiol, and; (2) one or more biodegradable polymers, all of which biodegradable polymers are polylactic acid (PLA) polymers, and; wherein the drug delivery system has a viscosity which permits the drug delivery system to be injected into an intraocular location through a 20 to 30 gauge syringe needle.
Patent NZ-611440-A (NZ)
Title: System for removal of hydrogen sulfide from geothermal steam and condensate
Inventor: DURHAM DANIEL K
IPC: B01D53/52
Filed: 2009-12-07
Abstract: A system for removing hydrogen sulfide from geothermal steam. The system includes a cooling tower with cooling water and acrolein feed line in fluid communication with the cooling tower. The system includes a condenser in fluid communication with the cooling tower through a flow line. The system also has a geothermal steam line in fluid communication with the condenser and a number of spray nozzles. The spray nozzles are in fluid communication with the flow line and are adapted to spray acrolein-water droplets inside the condenser.
Patent NZ-611662-A (NZ)
Title: Peptide-based in vivo sirna delivery system
Inventor: ROZEMA DAVID B
IPC: A61P35/00
Filed: 2011-12-16
Abstract: Disclosed is a conjugate delivery system composition for delivering an RNA interference polynucleotide to a liver cell in vivo comprising: RNAi-A + Melittin-(L-Gal)x wherein, Melittin is a melittin peptide; L is physiologically labile linkage; Gal is an Asialoglycoproteln Receptor (ASGPr) ligand; x is an integer having a value greater than 80% of primary amines of Melittin; RNAi is an RNA interference polynucleotide; and A is either a hydrophobic group having at least 20 carbon atoms or a galactose cluster.
Patent NZ-618165-A (NZ)
Title: An anode and cathode for a microbial fuel cell and a microbial fuel cell incorporating the anode or cathode
Inventor: ANDRESEN JOHN
IPC: H01M8/16
Filed: 2012-04-26
Abstract: An anode and a cathode for a microbial fuel cell and the microbial fuel cell incorporating such an anode and/or cathode are disclosed. The anode comprises at least one electrode element adapted to be received within the microbial fuel cell. The electrode element comprises polymer material having an electrically conductive material interspersed with the polymer material. The cathode comprises a polymer material having an electrically conductive material interspersed/integrated with the polymer material. The microbial fuel cell (1) comprises the above described anode (6) and cathode (7) arranged in a vessel (3) that contains a substrate. A method of forming the anode or cathode is disclosed. The anode (6) is adapted to harbour a microbial culture (10) to treat the waste water (2). A method of treating water using the above described microbial fuel cell (1) comprises providing the microbial fuel cell; introducing waste water (2) having an organic content to the cell and extracting water from the cell once the cell has reduced the organic content of the water. Also disclosed are methods of manufacturing an anode for a microbial fuel cell, coating an electrode with a catalyst and a method of collecting nitrogen based compounds contained in waste water, such as nitrates, using a microbial fuel cell.
Patent NZ-701336-A (NZ)
Title: Exercise/training machine
Inventor: WOOD SCOTT
IPC: B60N2/39
Filed: 2013-04-23
Abstract: An exercise/training device (10), which is particularly suitable for providing a workout for surfers but which also can be used as a general exercise device includes a platform ( 14) on which a user may kneel, sit, lie, stand or the like in use. The platform (14) is mounted on a support frame (12), the support frame including legs for supporting the top of the frame above ground level. A rod (18) or other similar member is mounted on the support frame and extends away from the platform. At least one resistance means (20) such as a pulley or the like, and a handle (120) is provided on the rod, which can be grasped by a user and pulled against a resistance. The platform (14) is mounted on the support frame by means of a mounting (16) which allows the platform (14) to tilt, particularly laterally from side to side about an axis which is parallel or co-axial to the axis of the rod. The mounting (16) may also allow longitudinal tilting, although typically this will be more limited than the lateral tilting. The mounting (16) is preferably adjustable to allow the degree of instability of the platform (14) to be adjusted and controlled.
Patent NZ-704604-A (NZ)
Title: Nep inhibitors for treating diseases characterized by atrial enlargement or remodeling
Inventor: SCHUMACHER CHRISTOPH
IPC: A61P9/06
Filed: 2013-08-22
Abstract: The present invention relates to the NEP inhibitor pro-drug N-(3-carboxy-1-oxopropyl)-(4S)-p-phenylphenylmethyl)-4-amino-(2R)-methylbutanoic acid ethyl ester, or a pharmaceutically acceptable salt thereof; or the NEP inhibitor N-(3-carboxy-1-oxopropyl)-(4S)-p-phenylphenylmethyl)-4-amino-(2R)-methylbutanoic acid, or a pharmaceutically acceptable salt thereof, pro-drug for use in the treatment, prevention or delay of progression of a disease characterized by atrial enlargement and/or remodeling; a method for treatment, prevention or delay of progression of a disease characterized by atrial enlargement and/or remodeling comprising administration of a therapeutically effective amount, or a prophylactically effective amount, of the NEP inhibitor or the NEP inhibitor pro-drug, or a pharmaceutically acceptable salt pro-drug thereof, to a subject, e.g. a human subject, in need of such treatment. The present invention further relates to a pharmaceutical composition or a commercial package comprising the NEP inhibitor or the NEP inhibitor pro-drug, or a pharmaceutically acceptable salt thereof, pro-drug for use in the treatment, prevention or delay of progression of a disease characterized by atrial enlargement and/or remodeling.
Patent NZ-705330-A (NZ)
Title: Laser cutting system and methods for creating self-retaining sutures
Inventor: NAIMAGON ALEXANDER
IPC: D02J3/10
Filed: 2011-05-04
Abstract: A laser-machining system and method is disclosed for forming retainers (130) on a suture thread (120). The laser system is preferably a femtosecond laser system which is capable of creating submicron features on the suture thread while preserving strength of the suture thread. The laser-machining system enables creation of retainers and self-retaining suture systems in configurations which are difficult and/or impossible to achieve using mechanical cutting technology. One method for making a self-retaining suture has the steps of (a) providing a suture thread having a surface; (b) identifying a first volume of suture material on the surface of the thread; (c) identifying a second volume of suture material from within the first volume of suture material; (d) directing a laser beam at the suture thread to ablate all of the suture material within the first volume of suture material with the exception of the second volume of suture material whereby the second volume of suture material forms a tissue retainer protruding from laser cut surface of the suture thread; and (e) repeating steps (b), (c) and (d) to generate a plurality of tissue retainers protruding from the suture thread.
Patent NZ-707156-A (NZ)
Title: Polyurethane vibratory screen
Inventor: COLGROVE JAMES R
IPC: B07B13/00
Filed: 2011-02-07
Abstract: A molded polyurethane vibratory screen including a body having opposite side edge portions, upper and lower edge portions, an upper surface and a lower surface, first members extending between the side edge portions and the second members extending between the lower edge portion and the upper edge portion, third members substantially parallel and extending transversely between the side edge portions and having multiple first members therebetween, the fourth members substantially parallel and extending transversely between the lower edge portion and the upper edge portion and having multiple second members therebetween, reinforcement members molded integrally with the third and fourth members. Various embodiments are disclosed with common feature of the reinforcing members running in both width and height directions.
Patent NZ-707196-A (NZ)
Title: Bottle with bridge and fluid channel
Inventor: LAIB DOUGLAS
IPC: B65D1/02
Filed: 2013-11-26
Abstract: A bottle (20) includes a bridge (38) forming a fluid channel, and extending radially outwardly on a bottle neck (28), from a location spaced axially from a bottle finish (32) to a bottle shoulder (26). The bridge includes an outer wall offset radially outwardly with respect to walls of the neck and the shoulder and, in transverse cross section, the outer wall includes an incurvate inner surface. The bridge also includes side walls (44) extending between the outer wall of the bridge and the walls of the neck and shoulder and, in transverse cross section, the side walls include straight inner surfaces disposed at chordal angles. The fluid channel formed by the bridge (38) provides improved product dispensing without requiring unconventional neck ring equipment or an unconventional closure design.
Patent NZ-708175-A (NZ)
Title: Peptides as oxytocin agonists
Inventor: BISSANTZ CATERINA
IPC: A61K38/095
Filed: 2013-12-17
Abstract: The invention relates to compounds of formula (I) wherein R1 is hydroxy or amino; R2 is sec-butyl or isobutyl; R3 is lower alkyl, lower alkyl substituted by hydroxy, -(CH2)2C(O)-NH2, -(CH2)3-NH2 or -CH2-five membered aromatic heterocyclic group; R4 is hydrogen or lower alkyl; R5 is hydrogen or lower alkyl; or R4 and R5 may form together with the N and C atom to which they are attached a pyrrolidine ring optionally substituted by hydroxy or halogen, a piperidine ring or an azetidine ring; R6 is hydrogen, lower alkyl, lower alkyl substituted by hydroxy, -(CH2)2C(O)OH, -(CH2)2C(O)NH2, benzyl optionally substituted by amino or hydroxy, -CH2-five membered aromatic heterocyclic group, indolyl, -CH2-cycloalkyl, cycloalkyl, -(CH2)2-S- lower alkyl or is -(CH2)1-4-NH2; R6’ is hydrogen or lower alkyl; or R6 and R6’ are together cycloalkyl; X is -C(O)-CHR-NR’-C(O)-; R/R’ are independently from each other hydrogen or lower alkyl; m is 2; O is 0 or 1; or a to pharmaceutically acceptable acid addition salt, to a racemic mixture or to its corresponding enantiomer and/or optical isomers thereof. It has been found that the present compounds are oxytocin receptor agonists for the treatment of autism, stress, including post traumatic stress disorder, anxiety, including anxiety disorders and depression, schizophrenia, psychiatric disorders and memory loss, alcohol withdrawel, drug addiction and for the treatment of Prader-Willi Syndrom.
Patent NZ-716820-A (NZ)
Title: Wear assembly
Inventor: CHEYNE MARK A
IPC: E02F9/28
Filed: 2012-07-12
Abstract: A wear assembly for use on various kinds of earth working equipment that includes a base with a supporting portion is disclosed. A wear member (10) with a cavity into which the supporting portion is received and a lock (16) to releasably secure the wear member to the base are also disclosed. The supporting portion is formed with top and bottom recesses that receive complementary projections of the wear member. These recesses and projections include aligned holes so as to receive and position the lock centrally within the wear assembly and remote from the wear surface. The hole in the wear member is defined by a wall that includes a retaining structure of upper and lower shoulders formed in the hole wall to secure the lock provided with an upper bearing surface and a lower bearing surface for contacting and retaining the lock against upward and downward movement in the hole.
Patent NZ-729290-A (NZ)
Title: Composition containing a mixture of plant extracts or a mixture of molecules contained in said plants, and use for controlling carbohydrate and/or lipid metabolism
Inventor: MAUGARD THIERRY
IPC: A61P9/00
Filed: 2015-10-20
Abstract: The present invention relates to the prevention and treatment of carbohydrate and/or fat metabolism disorders. There is a real need for products that can be used both during the attenuated establishment of cardio metabolic pathologies, characterized by an increase in certain risk factors (carbohydrate disorders, fat disorders, excess weight, inflammation, oxidative stress, arterial hypertension), and during the outbreak of these pathologies, especially type 2 diabetes. Moreover, there is an urgent need for preventive solutions and medicaments whose “multi target” mechanism of action has advantages in terms of compliance, tolerance and efficacy. Such products would make it possible to reduce the overall risk of cardio metabolic diseases and to prevent and treat each dysfunction and/or its consequences taken independently. The present invention provides compositions comprising at least a mixture of molecules comprising at least: an extract of Chrysanthellum indicum, an extract of Cynara scolymus, an extract of Vaccinium myrtillus, an extract of Olea europaea, and synthetic piperine and/or an extract of Piper containing piperine that are capable of acting simultaneously on several carbohydrate and fat dysfunctions, which represent both a preventive means and a therapeutic means for preventing and treating cardio-metabolic diseases and complications thereof.
Patent NZ-729884-A (NZ)
Title: Crystalline forms of 6-((6,7-dimethoxyquinazolin-4-yl)oxy)-n,2-dimethylbenzofuran-3-carboxamide
Inventor: WU ZHENPING
IPC: C07D405/12
Filed: 2015-09-07
Abstract: Crystalline forms of compound 6-(6,7-dimethoxyquinazolin-4-yloxy)-N,2- dimethylbenzofuran-3-carboxamide, pharmaceutical compositions and the methods of preparation and the use thereof.