baber/WOPTO huggingface dataset:
Patent CA-2543201-A1 (CA)
Title: ((ir, 3s)-3-isopropyl-3-{ [3-(trifluoromethyl)-7, 8-dihydro-1, 6-naphthyridin-6 (5h)- yl] carbonyl} cyclopentyl) [3s, 4s)-3-methoxytetrahydro-2h-pyran-4-yl] amine succinate salt, composition thereof, and its use in the treatment of inflammatory diseases
Inventor: LARSEN ROBERT
IPC: A61K31/4375
Filed: 2004-10-25
Abstract: The present invention provides an efficient synthesis for the preparation of ((1R,3S)-3-isopropyl-3-{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopentyl)[(3S,4S)-3-m ethoxytetrahydro-2H-pyran-4-yl]amine and its succinate salt. The present invention additionally provides an efficient syntheses for the preparation of intermediates (3R)-3-methoxytetrahydro-4H-pyran-4-one; (1<i>S</i>,4<i>S</i>)-4-(2,5-dimethyl-1<i>H</i>-pyrrol-1-yl)-1-isopropylcyclopent-2-ene-1-carboxylic acid; and 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine; and for the preparation of the precursor (3S,4S)-N-((1S,4S)-4-isopropyl-4-{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopent-2-e n-1-yl)-3-methoxytetrahydro-2H-pyran-4-amine. The invention additionally resides in the superior properties of the succinate salt of ((1R,3S)-3-isopropyl-3-{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopentyl)[(3S,4S)-3-m ethoxytetrahydro-2H-pyran-4-yl]amine.
Patent CA-2544280-A1 (CA)
Title: Restrictive reuse for a wireless communication system
Inventor: TEAGUE EDWARD H
IPC: H04W16/12
Filed: 2004-10-28
Abstract: For restrictive reuse, each cell (or each sector) is assigned (1) a set of usable subbands that may be allocated to users in the cell and (2) a set of forbidden subbands that is not used. The usable and forbidden sets for each cell are orthogonal to one other. The usable set for each cell also overlaps the forbidden set for each neighboring cell. A user u in a cell x may be allocated subbands in the usable set for that cell. If user u observes/causes high level of interference from/to a neighboring cell y, then user u may be allocated subbands from a "restricted" set containing subbands included in both the usable set for cell x and the forbidden set for cell y. User u would then observe/cause no interference from/to cell y. The subband restriction may be extended to avoid interference from multiple neighboring cells.
Patent CA-2544923-A1 (CA)
Inventor: IVERSEN PATRICK L
IPC: A61K48/00
Filed: 2004-11-05
Abstract: A method and compound for enhancing the lethality of an anti-cancer therapy, such as radiation, chemotherapy, or TRAIL protein, are disclosed. The compound is composed of morpholino subunits joined by phosphorodiamidate linkages, and has a targeting sequence that is complementary to an AUG start, IRES, or splice-donor region of the transcript for human X-linked inhibitor of apoptosis protein (XIAP). The method includes exposing cancer cells to the compound.
Patent CA-2546061-A1 (CA)
Inventor: SALEE DAVID A
IPC: B22D9/00
Filed: 2004-12-09
Abstract: An apparatus is described for starting and stopping a horizontal casting machine, e.g. a caster for continuous casting of metal ingots. The caster comprises a feed trough for carrying molten metal, at least one casting mould and a connecting trough separately connecting each casting mould to the feed trough. A shutoff gate is associated with each connecting trough and movable between an open position and a closed position. Each connecting trough includes a drop-down portion located between the shutoff gate and the casting mould, this drop-down portion being adapted to swing downwardly and thereby rapidly drain molten metal from the connecting trough and an entrance of the mould. The apparatus may also include an elongated starter block, adapted to be inserted into the casting mould and having a threaded recess formed therein for receiving molten metal. An O-ring is fitted to the starter block to seal the block against the casting mould.
Patent CA-2546382-A1 (CA)
Inventor: JESTER RANDY D
IPC: B32B27/08
Filed: 2004-10-13
Abstract: The present invention relates to a heat-sealable film which consists essentially of a cycloolefin copolymer (COC), the glass transition temperature (Tg) of the COC being within the range from 30 to 55~C. The film or sheet has excellent low temperature heat-sealing properties and processing characteristics. The film may be free standing or laminated to other thermoplastic polymer film or films at low temperatures. Alternatively, a COC  polymer with Tg in the range 30 to 55~C may be coextruded with other thermoplastic polymer or polymer films in a coextrusion process to form a heat sealable film. The film of the invention is suitable for packing foods or other consumable items.
Patent CA-2546770-A1 (CA)
Inventor: WILLEY WILLIAM DANIEL
IPC: G06Q10/00
Filed: 2006-05-12
Abstract: A system and method for automatically determining whether or not original message text should be included in a reply electronic message is provided. In one broad aspect, the original message text is included in the reply electronic message as a function of the original message. In a first example, the original message text is included as a function of a domain name of an originating address. In a second example, the original message text is included as a function of maintained information used for determining if original message text should be included in reply electronic messages. In a third example, the original message text is included as a function of an indicative encoding inside the original electronic message. In a fourth example, the original message text is included as a function of maintained information used for detecting address aliases. In another broad aspect, the original electronic message is encoded with an indicative encoding as to whether or not a reply electronic message should include the original message text.
Patent CA-2546922-A1 (CA)
Inventor: ZICHI DOMINIC
IPC: C12Q1/68
Filed: 2004-11-16
Abstract: The invention provides general methods for adjusting the inherent quantification range of a particular set of analytes in assays that employ capture reagents immobilized on solid supports. Specifically, the quantification range of a given analyte is adjusted to higher concentration regions by the addition of free capture reagent specific for that analyte, leaving the range of the remaining analytes the same and thereby permitting the simultaneous and accurate quantification of a plurality of analytes over a wide range of concentration values.
Patent CA-2549111-A1 (CA)
Title: Doxepin analogs and methods of use thereof
Inventor: WHITE JAMES F
IPC: A61K31/675
Filed: 2004-12-10
Abstract: The invention relates to novel doxepin analog compounds and methods of modulating sleep by administering such compounds, or a pharmaceutically effective salt thereof.
Patent CA-2549227-A1 (CA)
Inventor: GIBBERD MARK RAYMOND
IPC: B32B7/02
Filed: 2004-12-03
Abstract: This invention relates to packaging materials comprising a water-impermeable outer layer bonded to a water-absorbent layer and having an inner layer that is water vapour-permeable, and to processes for the manufacture thereof. The invention also provides for the storage and/or transport of perishable goods, and in particular for the storage and transport of horticultural produce such as fruit, vegetables and cut flowers. The present invention also provides a method of regulating the O2 content in the environment surrounding packaged perishable goods.
Patent CA-2549381-A1 (CA)
Inventor: JAEMIAE AULIS
IPC: B29C48/305
Filed: 2004-12-13
Abstract: A method to furnish the edge portion of sheet (1) with a strip, as a strip (2) of plastic material using device (3) comprising a die space (7). The edge of sheet (1) is fitted inside device (3) that feeds plastic material to die space (7) and by means of restrictive organs (8) and die surfaces, of which device the escape of heated plastic material from a die space (7) is avoided, the sheet is arranged to move in regard to the feeding (3) device, the sheet edge being inside said device, die space (7) of device (3) is heated during the process.
Patent CA-2552116-A1 (CA)
Title: Gas stove burner
Inventor: PUABHANICH KUAKOON
IPC: F24C3/08
Filed: 2006-07-12
Abstract: The principle of the burner is to increase the speed of the gas stream in the gas stove burner and to heat up. The projecting ridges along the inner gas pipe and the cylinder serve to form an array of the gas stream. The curved round and disproportional shape like a bowl in the cylinder and the curved ridges sloping at the front and bending over to the back surround the gas stream coming out from the gas pipe so the gas stream in the cylinder changes the direction and speed up directly to the gas holes. The dense and solid projecting ridges at the center of the cylinder help maintain and heat up the inner frame. The inner side of the cover disk possessing respective big and small projecting ridges between inner and outer gas holes speed up the gas stream and reduce the reflection force. The appropriated voids size or holes on the wings of the gas stove frame let the cold air from outside come in to accomplish better the combustion.
Patent CA-2552183-A1 (CA)
Title: Embedding advertisements in syndicated content
Inventor: MINAR NELSON
IPC: G06Q30/00
Filed: 2004-12-21
Abstract: Incorporating targeted ads into information in a syndicated, e.g., RSS, presentation format in an automated manner is described. Syndicated material e.g., corresponding to a news feed, search results or web logs, are combined with the output of an automated ad server. An automated ad server is used to provide keyword or content based targeted ads. The ads are incorporated directly into a syndicated feed, e.g., with individual ads becoming items within a particular channel of the feed. The resulting syndicated feed including targeted ads is supplied to the end user, e.g., as a set of search results or as a requested web log. Embedding of targeted ads into syndicated feeds and/or user response to the embedded ads is be tracked in an automated manner for billing. The automated targeting and insertion process allows ads to be kept current and timely while the original feed may be considerably older.
Patent CA-2554238-A1 (CA)
Title: Use of a serum-free cell culture medium for the production of il-18bp in mammalian cells
Inventor: ZIEGLER THIERRY
IPC: C07K14/47
Filed: 2005-02-28
Abstract: The invention relates to a process for culturing IL-18BP expressing mammalian cells under serum-free conditions.
Patent CA-2554248-A1 (CA)
Title: Neural stimulation array providing proximity of electrodes to cells via cellular migration
Inventor: HUIE PHILIP JR
IPC: A61N1/36
Filed: 2005-01-18
Abstract: An interface for selective excitation or sensing of neural cells in a biological neural network is provided. The interface includes a membrane with a number of channels passing through the membrane. Each channel has at least one electrode within it. Neural cells in the biological neural network grow or migrate into the channels, thereby coming into close proximity to the electrodes. Once one or more neural cells have grown or migrated into a channel, a voltage applied to the electrode within the channel selectively excites the neural cell(s) in that channel. The excitation of these neural cell(s) will then transmit throughout the neural network (i.e. cells and axons) that is associated with the neural cell(s) stimulated in the channel.  An alternative interface provides cell excitation via an array of electrically conductive pillars on a substrate. The pillars have electrically insulated sides and exposed top surfaces, to provide selective cell excitation.
Patent CA-2555685-A1 (CA)
Inventor: WANG HUI-LING
IPC: C07D403/12
Filed: 2005-02-11
Abstract: Pyrimidine ethers and compositions containing them, fo use as vanilloid receptor ligands for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders. Wherein R1 - R4 and X are as defined in the claims.
Patent CA-2557690-A1 (CA)
Inventor: MECKLENBURG GEORGS A
IPC: G01N33/487
Filed: 2005-03-31
Abstract: A biosensor system, method and apparatus are provided for implementing threshold based correction functions for biosensors. A primary measurement of an analyte value is obtained. A secondary measurement of a secondary effect is obtained and is compared with a threshold value. A correction function is identified responsive to the compared values. The correction function is applied to the primary measurement of the analyte value to provide a corrected analyte value. The correction method uses correction curves that are provided to correct for an interference effect. The correction curves can be linear or non-linear. The corrction method provides different correction functions above and below the threshold value. The correction functions may be dependent or independent of the primary measurement that is being corrected. The correction functions may be either linear or nonlinear.
Patent CA-2557830-A1 (CA)
Title: A method and a device for sealing a void incompletely filled with a cast material
Inventor: FREYER RUNE
IPC: E21B33/14
Filed: 2005-12-12
Abstract: A method and a device for sealing a void incompletely filled with a cast material, in which an expandable material is placed in the void which is to be filled with a cast material, the expandable material expanding, when expanding after the cast material has cured, into spaces which are not filled with cast material.
Patent CA-2559580-A1 (CA)
Inventor: HABIG MICHAEL
IPC: C12M3/00
Filed: 2005-03-15
Abstract: Container (A) comprises reaction spaces (RS), each of which contains at least one electrode pair for generating an electrical field in RS when a voltage is applied. At least two first electrodes in different RS are electrically connected and at least one second electrode of one RS is electrically connected, separately. Independent claims are also included for the following: (1) method for preparing (A); and (2) device (B) for electrically contacting at least one (A).
Patent CA-2560341-A1 (CA)
Title: Fungicidal mixtures
Inventor: MUELLER BERND
IPC: A01N47/04
Filed: 2005-04-23
Abstract: Disclosed are fungicidal mixtures containing 1) a sulfamoyl compound of formula (I), wherein the substituents have the following meaning: R1 represents hydrogen, halogen, cyano, alkyl, alkyl halide, alkoxy, alkylthio, alkoxycarbonyl, phenyl, benzyl, formyl, or CH=NOA; A represents hydrogen, alkyl, alkylcarbonyl; R2 represents hydrogen, halogen, cyano, alkyl, alkyl halide, alkoxycarbonyl; R3 represents halogen, cyano, nitro, alkyl, alkyl halide, alkoxy, alkylthio, alkoxycarbonyl, formyl, or CH=NOA; n represents 0, 1, 2, 3, or 4; R4 represents hydrogen, halogen, cyano, alkyl, or alkyl halide;  and 2) at least one active substance selected among the following groups: A) azoles; B) strobilurine; C) acylalanine; D) amine derivatives; E) anilinopyrimidines; F) dicarboximides; G) cinnamides and analogs; H) dithiocarbamates; I) heterocyclic compounds; K) sulfur and copper fungicides;  L) nitrophenyl derivatives; M) phenylpyrroles; N) sulfenic acid derivatives;  O) other fungicides; according to the description, at a synergistically effective quantity as active components. Also disclosed are methods for controlling harmful fungi with the aid of mixtures of compound (I) and active substances from groups A) to O), the use of compounds (I) along with active substances from groups A) to O) for producing such mixtures, and agents containing said mixtures.
Patent CA-2561751-A1 (CA)
Inventor: GELFAND MATTHEW
IPC: E01F13/12
Filed: 2005-03-31
Abstract: Système d'absorption d'énergie. Ce système s'étend d'un côté à l'autre d'une voie de circulation et comprend un filet traversant ladite voie et possédant un élément d'accouplement accouplé à un élément supérieur, un élément médian et un élément inférieur, ainsi qu'un mat disposé sur la voie de circulation et comportant une pluralité d'évidements afin de loger le filet quand ce dernier se trouve en position abaissée.
Patent CA-2562454-A1 (CA)
Inventor: PIPPIA ENNIO
IPC: F25D23/00
Filed: 2006-10-04
Abstract: Refrigeration apparatus comprising a cold storage compartment, accessible from the outside, and provided internally with a sealed container adapted to accommodate a flexible and compressible receptacle holding a beverage; there are provided pneumatic or air-compression means to generate a selectively controllable pneumatic pressure inside said container, but outside said flexible receptacle, and said sealed container is capable of being opened from the outside by means of a closure applied on a face thereof, wherein said closure is provided with a through-aperture, through which there extends a drawing-off conduit. Whenever a need arises for beverage to be drawn off the receptacle, a pressure increase is triggered inside the sealed container, and said pressure increase will act upon the walls of the internal receptacle so that the latter is caused to collapse and reduce its volume, thereby causing the beverage to be ejected therefrom and, therefore, drawn off.
Patent CA-2563906-A1 (CA)
Inventor: ALLROTH SVEN
IPC: B22F1/00
Filed: 2005-04-20
Abstract: The invention concerns a method for producing products and a coarse iron-based powder comprising a lubricant having a crystalline melting point below 25 ~C, a viscosity (.eta.) at 40 ~C above 15 mPas and wherein said viscosity is temperature dependent according to the following formula: 10log.eta.=k/T+C, wherein the slope k is preferable above 800, T is temperature in Kelvin and C  is a constant, in an amount of 0.05-0.4w- %.
Patent CA-2564478-A1 (CA)
Inventor: SLOMSKI EDWARD J
IPC: B65D71/50
Filed: 2004-12-21
Abstract: A carrier (10) for containers has loops (52, 54, 56, 58, 60)for individually securing containers therein and perfection lines (76) through the carrier for separating the carrier into at least two subgroups (90, 92) of containers without removing containers from the loops.
Patent CA-2564702-A1 (CA)
Title: Catalysts
Inventor: TURNER JILL
IPC: C07C209/36
Filed: 2005-05-10
Abstract: A method of manufacturing a cobalt catalyst is described, which comprises the steps of forming an aqueous solution of a cobalt amine complex, oxidising said solution such that the concentration of Co(I11) in the oxidised solution is greater than the concentration of Co(III) in the un- oxidized solution, and then decomposing the cobalt amine complex by heating the solution to a temperature between 80 and 110 ~C for sufficient time to allow an insoluble cobalt compound to precipitate out of the solution. A catalyst intermediate is also described which comprises a cobalt compound, comprising a Co(II)/Co(III) hydrotalcite phase and a Co3O4 cobalt spine) phase, wherein the ratio of cobalt hydrotalcite phase : cobalt spine) phase is less than 0.6:1, said cobalt hydrotalcite phase and said cobalt spine) phase being measured by X-ray diffractometry.
Patent CA-2565104-A1 (CA)
Title: Filters having improved permeability and virus removal capabilities
Inventor: GOLDMAN STEPHEN ALLEN
IPC: C02F1/28
Filed: 2005-05-05
Abstract: A filter block having a permeability of greater than about 3.0*10-9cm2, and a F-VLR of greater than about 99% is provided. The filter block may be made of filter particles having a median particle size of less than about 50 microns and having a particle span of about 1.4 or less. The filter blocks of the present invention can be used to make a filter for filtering liquids and more specifically, for providing potable water. The filter particles may be mesoporous. Kits comprising filters and information relating to the killing or removal of bacteria, viruses, and microbials are also provided.
Patent CA-2567128-A1 (CA)
Title: Steam cracking of hydrocarbon feedstocks containing salt and/or particulate matter
Inventor: STELL RICHARD C
IPC: C10G9/00
Filed: 2005-05-19
Abstract: A process for cracking a hydrocarbon feedstock containing salt and/or particulate matter, wherein said hydrocarbon feedstock containing salt and/or particulate matter is heated, then separated into a vapor phase and a liquid phase by flashing in a flash separation vessel, separating and cracking the vapor phase which comprises less than about 98% of the hydrocarbon feedstock containing salt and/or particulate matter, and recovering cracked product. The salt and/or particulate matter are removed in the liquid bottoms stream from the flash separation vessel. The liquid phase could then be sold as bunker C  fuel oil or fed to a refinery catalytic cracker or coker unit without desalting.
Patent CA-2567823-A1 (CA)
Title: In vitro platform for screening agents inducing islet cell neogenesis
Inventor: ROSENBERG LAWRENCE
IPC: C12Q1/68
Filed: 2004-05-27
Abstract: The present invention relates to an in vitro method for screening agents inducing islet cell neogenesis or duct-to-islet cell transdifferentiation, which comprises the steps of: a) expanding in vitro cells of a duct-like structure obtained by inducing cystic formation in cells in or associated with post-natal islets of Langerhans; b) treating said expanded cells of said duct-like structure with an agent screened; and c) determining potency of said agent of inducing islet cell differentiation of said duct-like structure in becoming insulin-producing cells.
Patent CA-2567879-A1 (CA)
Title: Nutritional food oil compositions and methods of making same
Inventor: GREITHER THOMAS
IPC: A23L33/12
Filed: 2006-11-14
Abstract: Nutritional food oil compositions containing all of the essential fatty acids and the highly recommended omega-3 fatty acid DHA in correct proportions making it convenient and easy for consumers to supplement their diets with these fatty acids in the proper amounts, thereby deriving the health benefits of these fatty acids. A  nutritional food oil composition is provided comprising alpha-linolenic acid (ALA) and linoleic acid (LA), wherein the ratio of the amount of ALA to LA in the composition by weight is in the range of 1.5:1 to 6:1, and together the ALA and LA comprise at least 65% by weight of the composition, and docahexaenoic acid (DHA) from an algal source in an amount greater than 0.5% by weight of the composition.
Patent CA-2571510-A1 (CA)
Inventor: TSUDA KAZUHIRO
IPC: B32B27/00
Filed: 2005-06-08
Abstract: An adhesive sheet which can prevent or remove a bubble and a blister by a through hole and has a base material surface whereupon the through hole is not easily seen. On an adhesive surface of an adhesive agent layer (12) of a laminated body composed of a base material (11) and the adhesive agent layer (12), CO2 laser beams having a pulse width of 1-140µsec, a pulse energy of 0.01-3.0mJ at a processing point and a beam spot diameter of 30-160µm at the processing point are applied, and through holes (2) having a hole diameter of 0.1-42µm on the surface of the base material (11) are formed at a hole density of 30-50,000 holes/100cm2.