baber/WOPTO huggingface dataset:
Patent DE-69813539-D1 (DE)
Inventor: MARUYAMA TATSUYA
IPC: C07D277/46
Filed: 1998-01-22
Granted: 2003-05-22
Abstract: An amide derivative represented by the following general formula (I) or a salt thereof and a pharmaceutical composition containing the amide derivative and a pharmaceutically acceptable vehicle. <CHEM>  (The symbols in the formula have the following meanings. (wherein   A:   heteroarylene; X:   bond, O, S, -NR<5>-, -NR<5>CO-, -NR<5>CONH-, -NR<5>SO2- or -NR<5>C(=NH)NH-; R<1>:   -H, -optionally substituted lower alkyl, -optionally substituted aryl, -optionally substituted heteroaryl or -optionally substituted cycloalkyl; R<2a>, R<2b>:   -H or -lower alkyl, which may be the same or different; R<3>:   -H or -lower alkyl; R<4a>, R<4b>:   -H or -OH, which may be the same different, or R<4a> and R<4b> are taken together to form =O or =N SIMILAR O-lower alkyl; and R<5>:   -H or -lower alkyl.)
Patent DE-69822476-D1 (DE)
Inventor: SALTER ANN
IPC: C09K23/00
Filed: 1998-08-06
Granted: 2004-04-22
Abstract: This invention relates to an anionic alkoxylate surfactant (I), where R is di- or tri-unsaturated C4-22 straight or branched hydrocarbon chain, at least two double bonds of said unsaturated chain being conjugated and exhibiting opposite geometric isomerism; m is 0 or 1; Y is O or NR; each R40  is independently selected from hydrogen, C1-6 alkyl and phenyl; n is 1 to 50; and OX is an anionic group selected from the group consisting of acids or salts of sulphate, phosphate, sulphosuccinate, succinate, carboxymethyl, maleate, carboxyethyl, alkenylsuccinate, phthalate, sulphoethyl, 3-sulpho-2-hydroxypropyl, sulphopropyl, oxalate and citrate.
Patent DE-69828070-D1 (DE)
Inventor: ERWIN L
IPC: B29D11/00
Filed: 1998-06-12
Granted: 2005-01-13
Abstract: Laminae suitable for use in molds for forming retroreflective cube corner elements and methods for making such laminae are disclosed. A representative lamina includes a first row of cube corner elements disposed in a first orientation and a second row of optically opposing cube corner elements disposed. The working surface of a lamina is provided with a plurality of cube corner elements formed by the optical surfaces defined by three groove sets. Opposing first and second groove sets are formed in the working surface of a lamina. The first groove set forms a plurality of structures having first and second optical surfaces disposed in mutually perpendicular planes that intersect along a reference edge. The second groove set forms a corresponding plurality of structures on the opposite side of the lamina. A third groove is formed in the working surface of the lamina along an axis substantially perpendicular to the axes of the grooves of the first and second groove sets. The surfaces of the third groove intersect the surfaces of the plurality of structures in substantially mutually perpendicular planes to define a plurality of cube corner elements. A plurality of such laminae can be assembled to form a mold useful in the manufacture of retroreflective products such as cube corner sheeting.
Patent DE-69831611-D1 (DE)
Inventor: RAMASWAMY SOWMIANARAYANAN
IPC: C07D211/26
Filed: 1998-05-26
Granted: 2005-10-20
Abstract: A process for preparing  d-threo  methyl ±- piperid-2-ylarylacetates of formula III:   
wherein R 1  is aryl having 6 to 28 carbon atoms, comprising the steps of:  reacting a pyridine having formula I:     
wherein R 1  is aryl having 6 to 28 carbon atoms with hydrogen in an alkanoic acid having 1 to 10 carbon atoms and in the presence of a catalyst to provide a mixture of  threo  and  erythro  piperidine stereoisomers having formulas IIa-d:      
adding an alkyl alkanoate having 2 to 20 carbon atoms to said mixture, thereby precipitating alkanoate salts of said  erythro  stereoisomers preferentially with respect to alkanoate salts of said  threo  stereoisomers; 
reacting said  erythro  alkanoate salts with aqueous base to form said  erythro  stereoisomers; 
reacting said  erythro  stereoisomers with an acid resolving agent in an alkyl alcohol having 1 to 5 carbon atoms, thereby forming acid salts of said  1-erythro  stereoisomers preferentially with respect to said  d-erythro  stereoisomers; 
reacting said  1-erythro  acid salts with aqueous base to form said  1-erythro  piperidine; 
reacting said  1-erythro  piperidine with an alkali metal alkoxide having one to 10 carbon atoms in organic solvent, whereby forming said  d-threo  piperidine, and 
converting said  d-threo  piperidine to said  d-threo  methyl ±- piperid -2- ylarylacetate.
Patent DE-69834127-D1 (DE)
Inventor: LEE CHENG-CHI
IPC: C07H21/04
Filed: 1998-01-07
Granted: 2006-05-18
Abstract: The present invention provides a method of screening individuals at risk for developing diseases caused by trinucleotide repeat sequence instability. Specifically, the present invention is drawn to screening individuals at risk for developing autosomal dominant spinocerebellar ataxia type 6 by determining the length of a CAG trinucleotide repeat in the alpha<SUB>1A </SUB>calcium channel gene of the individual. In addition, there is provided a method of identifying genes which are disease-causing due to trinucleotide repeat sequence instability by large scale genotyping.
Patent DE-69837975-D1 (DE)
Inventor: KLAVENESS JO
IPC: A61K49/22
Filed: 1998-04-24
Granted: 2007-08-02
Abstract: The invention provides a method of generating an image of an animate human or non-human animal subject previously administered with a contrast agent involving generating an image of at least a part of said subject to which said contrast agent has distributed, characterised in that said contrast agent is a composition of matter of formula I V - L - R where V is a vector moiety having affinity for an angiogenesis-related endothelial cell receptor, L is a linker moiety or a bond and R is a detectable moiety, characterised in that V is a non-peptidic organic group, or V is peptidic and R is a macromolecular or particulate species providing a multiplicity of labels detectable in in vivo imaging.
Patent DE-69902447-D1 (DE)
Inventor: JOBBINS M
IPC: C04B24/26
Filed: 1999-03-16
Granted: 2002-09-12
Abstract: A composition of matter comprising(a) gypsum (CaSO4 . 2H2O);(b) one or more naturally occurring or synthetic latex polymers; and(c) one or more nonionic surfactants; wherein said composition of matter has a density less than 0.64 g/cm3 and wherein wallboard produced from said composition of matter satisfies the criteria of ASTM Methods C-36 and C-473 is provided.
Patent DE-69906976-D1 (DE)
Inventor: ROSATO LORENZO
IPC: A43B3/00
Filed: 1999-07-12
Granted: 2003-05-22
Abstract: The finding is a skate (1) with inline wheels (5) composed of: a shell (2) with a sole (3) on which the sole of the foot rests; a bootleg (6) fixed with pins to the rear part of the shell (2) which houses the heel of the foot and supports the ankle; a number of wheels (5) aligned along a support (4) fixed to the sole (3); sliding coupling means (12) that connect the bootleg (6) to the shell (2) to adjust the shoe size and locking devices (16) to fix the bootleg (6) selectively to the shell (2). The sole (3) has a projection (21) at the rear incorporated with the sole (3), this slides into a through aperture (22) in the bootleg (6) so that the sole (3) extends uninteruptedly for the entire length of the foot of the skater in any position adopted by the bootleg (6) in relation to the shell (2).
Patent DE-69910373-D1 (DE)
Inventor: MAKRIYANNIS ALEXANDROS
IPC: C07D409/04
Filed: 1999-05-04
Granted: 2003-09-18
Abstract: Disclosed are novel compounds represented by the following structural formula: <?in-line-formulae description="In-line Formulae" end="lead"?>R-X-Y;<?in-line-formulae description="In-line Formulae" end="tail"?> and physiologically acceptable salts thereof. R is a tricyclic core of a cannabinoid or substituted cannabinoid. X is a covalent bond, -CH<SUB>2</SUB>- or -CHR<SUB>1</SUB>-, wherein R<SUB>1 </SUB>a C1 to C3 substituted or unsubstituted alkyl group. Y is a heterocyclic ring, a substituted heterocyclic ring, a carbocyclic ring, a substituted carbocyclic ring, a fused bicyclic ring system, a substituted fused bicyclic ring system, a bridged bicyclic ring system, a substituted bridged bicyclic ring system, a bridged tricyclic ring system or a substituted bridged tricyclic ring system. Also disclosed is a method of stimulating a CB1 and/or CB2 receptor in a subject. The method comprises administering to the subject a therapeutically effective amount of R-X-Y.
Patent DE-69910574-D1 (DE)
Inventor: OLSON ERIC
IPC: C07D487/04
Filed: 1999-06-18
Granted: 2003-09-25
Abstract: The present invention describes novel pyrazolo[1,5-a]triazines of formula:wherein R3 is an alkyl, alkenyl, alkynyl, or cycloalkyl group, or pharmaceutically acceptable salt forms thereof, which are useful as CRF antagonists.
Patent DE-69913186-D1 (DE)
Inventor: FOREST KATRINA T
IPC: A01N1/02
Filed: 1999-10-13
Granted: 2004-01-08
Abstract: The present invention relates to a method of vitrification of a biological specimen. According to the method of the present invention, a biological specimen is directly exposed to a freezing material. Upon exposure to the freezing material, the biological specimen undergoes vitrification. The biological specimen which has undergone vitrification may be stored for a period of time, and then thawed at a later date. The thawed biological specimen remains viable. Preferred biological specimens according to the present invention are developmental cells.
Patent DE-69915627-D1 (DE)
Title: Estersynthese
Inventor: FROOM FREDERICK
IPC: C07C69/14
Filed: 1999-07-01
Granted: 2004-04-22
Abstract: Process for the production of lower aliphatic esters comprising reacting a lower olefin with a saturated lower aliphatic monocarboxylic acid in the vapor phase in the presence of a heteropolyacid catalyst. The reaction is carried out in a plurality of reactors set up in series, and the feedstock is rendered substantially free of metallic or metal compound impurities prior to being brought into contact with the heteropolyacid catalyst.
Patent DE-69916289-D1 (DE)
Inventor: ELLIOTT T
IPC: C07H5/04
Filed: 1999-08-18
Granted: 2004-05-13
Abstract: The invention concerns a novel phosphoglycolipid compound. The compound of the subject invention is 2-Deoxy-6-O-[2-deoxy-4-O-phosphono-3-O-[(R)-3-tetradecanoyloxytetradecanoyl]-2-[(R)-3-octadecanoyloxytetradecanoylamino]- beta -D-glucopyranosyl]-2-[(R)-3-hexadecanoyloxytetradecanoylamino]-D-glucopyranose and pharmaceutically acceptable salts thereof. The compound is not immunoreactive, not pyrogenic, not toxic but is active in ameliorating tissue damage due to ischemia/reperfusion injury. Methods for using the subject compound to protect against reversible and irreversible damage due to ischemia/reperfusion injury are also disclosed.
Patent DE-69917901-D1 (DE)
Inventor: HUTCHINS ALLEN
IPC: A61Q5/06
Filed: 1999-04-27
Granted: 2004-07-15
Abstract: Disclosed are anhydrous aerosol hairspray compositions which comprise (a) from about 0.1% to about 10% by weight of a silicone-grafted polycarboxylic acid copolymer having a weight average molecular weight of from about 10,000 to about 300,000, wherein the silicone-grafted polycarboxylic acid copolymer has a vinyl polymeric backbone, and a polysiloxane macromer grafted to the backbone wherein the polysiloxane macromer has a weight average molecular weight of from about 500 to about 50,000; (b) a neutralizing system comprising a combination of an organic and inorganic base, wherein the organic base is at a level sufficient to neutralize from about 25% to about 80% of the acid groups on the silicone-grafted copolymer while the inorganic base is at a level sufficient to neutralize from about 0.5% to about 20% of the acid groups on the silicone-grafted copolymer; (c) from about 5% to about 50% by weight of a nonhydrocarbon propellant that is substantially free of hydrocarbon propellants; and (d) the balance comprising a carrier suitable for application to hair. The anhydrous aerosol hairspray compositions defined herein do not weep or foam from the hairspray container, provide effective style retention, hair conditioning benefits, and do not feel unduly sticky or tacky to the touch.
Patent DE-69924041-D1 (DE)
Inventor: GROVE YATES
IPC: A61H1/02
Filed: 1999-12-21
Granted: 2005-04-07
Abstract: A foot dorsiflexion device comprises at least one portable boot, which can be submersed in liquids if desired, worn by a patient, having a baseplate and a footplate affixed at one end to the baseplate. An inflatable bellows is positioned between the baseplate and footplate, such that inflating the bellows moves the footplate relative to the baseplate to effect flexion of the patient's foot. A controller controls the pumping sequence of a pump which can inflate one or more boot devices. In another feature, the controller also receives information as to the patient's leg muscle activity and responds appropriately to stop/re-start the device. Such a feedback mechanism is useful to prevent flexion during an abnormal contraction pattern, such as occurs in muscle spasm or tetany. The device is can be operated remotely and in both automatic and manual modes by the user or operator.
Patent DE-69931980-D1 (DE)
Inventor: HIGGINS GEORGE ANTHONY
IPC: H05B3/68
Filed: 1999-01-05
Granted: 2006-08-03
Abstract: A radiant electric heater has first, second and third heating zones (1, 2, 3) arranged substantially side-by-side. The first heating zone (1) is provided with at least one first heating element (9). The second heating zone (2) is arranged adjacent to the first heating zone and is provided with at least one second heating element (10). The third heating zone (3) is arranged adjacent to the second heating zone and is provided with at least one third and one fourth heating element (11, 12). A switch (15) is provided for switching between first, second and third heating states. In the first heating state the at least one first heating element (9) of the first heating zone (1) is energised alone, the at least one second, third and fourth heating elements (10, 11, 12) of the second and third heating zones (2, 3) being de-energised. In the second heating state the at least one first heating element (9) of the first heating zone (1) is electrically connected and energised in parallel with the at least one second heating element (10) of the second heating zone (2), the at least one third and fourth heating elements (11, 12) of the third heating zone (3) being de-energised. In the third heating state the at least one first heating element (9) of the first heating zone (1) is electrically connected in parallel with the at least one second heating element (10) of the second heating zone (2) and the parallel-connected at least one first and at least one second heating elements are connected in series with the at least one third heating element (11) of the third heating zone (3) to form a combination, which combination is electrically connected in parallel and energised with the at least one fourth heating element (12) of the third heating zone (3). <IMAGE>
Patent DE-69935599-D1 (DE)
Inventor: BERZOFSKY JAY A
IPC: C12N5/06
Filed: 1999-08-17
Granted: 2007-05-03
Abstract: Provided are an isolated peptide having the amino acid sequence DLMGYIPAV (SEQ ID NO: 1), an isolated HCV core polypeptide comprising an L->A substitution at amino acid position 139, an isolated HCV core polypeptide having the amino acid sequence of SEQ ID NO: 2, and a fragment of an HCV core polypeptide having fewer amino acids than the entire HCV core polypeptide and comprising the amino acid sequence of SEQ ID NO:1. Also provided are nucleic acids which encode the peptides and polypeptides of this invention, vectors comprising the nucleic acids of this invention and cells comprising the vectors and nucleic acids of this invention. Further provided are methods of producing an immune response in a subject and/or treating or preventing HCV infection in a subject, comprising administering to the subject, or to a cell of the subject, any of the compositions of this invention.
Patent DE-69939315-D1 (DE)
Inventor: OSTLUND RICHARD E
IPC: A23L33/20
Filed: 1999-03-25
Granted: 2008-09-25
Abstract: Compositions useful to reduce cholesterol absorption. The compositions may be dosed in capsule or tablet form, or by adding either in liquid or dry powder form to foods and beverages. The compositions are an aqueous based homogeneous micellar mix which is dried to provide a mixture of finely-divided plant sterol, preferably sitostanol and lecithin. The mole ratio of the plant sterol, preferably sitostanol to lecithin, should be within the range of 1:1 to 1:10, preferably at least 1:2.
Patent DE-502004001973-D1 (DE)
Inventor: GROEGER MARTIN
IPC: H04L69/40
Filed: 2004-12-23
Abstract: The translator has watch dog circuits (WD1, WD2) designed to keep close connection between a data network with lower security level and data network with higher security level, as long as it receives a regular sign of life from one test component. Another checking component is designed to suppress a generation of signs of life for a preset period after receiving a checking telegram that is not permitted based on filter rules. An independent claim is also included for a method for integrity checking of a device.
Patent DE-502004002665-D1 (DE)
Inventor: WEBER HUGO
IPC: E04D13/00
Filed: 2004-11-10
Abstract: Additional layers (1.2-1.n) have a moveable connection with the lower layer (1.1). The layers are made from diverse materials with various textures and optional perforations.
Patent DE-502004005525-D1 (DE)
Inventor: MOCIVNIK JOSEF
IPC: E21B21/00
Filed: 2004-09-28
Abstract: The invention relates to a method and a device for boring, especially for the percussion boring or rotary percussion boring of holes in soil or rock. According to the invention, a borehole is formed by a percussive and/or rotary movement carried out by a bore-crown (2) mounted on a boring rod (3), and a jacket or envelope tube (4, 6) is introduced into the borehole. The invention is characterised in that the extracted material is transported through at least one opening located in the region of the connection point between the bore-crown (2) and an adjacent envelope tube (4), and/or at least one through opening (24) located at a distance from the connection point between the bore-crown (2) and the envelope tube (4), in the annular region (31) defined between the outer periphery of the boring rod (3) and the inner periphery of the envelope tube (4) and the adjacent jacket tube (6), and is removed from the borehole. In this way, extracted material can be removed in a safe and reliable manner.
Patent DE-502004006287-D1 (DE)
Inventor: WELSCH FRANK DR
IPC: B62D21/10
Filed: 2004-01-13
Abstract: The floor stiffening structure is added to the floor sheet (1) and has at least one longitudinal bearer element (3, 6, 7) fitted from below and extending over its entire length. This bearer element extends into the upward-pointing structure of the heel plate (2) and is firmly fixed to it and to the floor sheet. In a collision, the front structure is diverted further downwards, out of the way of the occupants.
Patent DE-502004008571-D1 (DE)
Inventor: EWIG ANDRE
IPC: F41A23/20
Filed: 2004-07-02
Abstract: The weapon station comprises a closed housing (1), with a pivotable cradle bearing (2) for a primary weapon (2) such as a tank gun, and a sight (3) arranged on one side of the primary weapon, directly adjacent to the bearing. A secondary weapon (4) such as a machine gun is arranged on the other side of the primary weapon.
Patent DE-502004009964-D1 (DE)
Inventor: REISS INGO
IPC: A23L27/00
Filed: 2004-02-28
Abstract: The use of 6,6'-dihydroxy-5,5'-dimethoxy-[1,1'-biphenyl]-3,3'-dicarboxaldehyde (divanillin) as a flavouring is described. Also described are flavouring compositions and foodstuffs comprising divanillin in a sensorially effective amount.
Patent DE-502005000120-D1 (DE)
Inventor: LEHMANN RAINER
IPC: B65C9/22
Filed: 2005-06-04
Abstract: The assembly to apply glue to labels has an initial applicator with jets to apply the glue in local points, and a final stage where vertical glue strips are formed by a glue bar (5). The bar has a main glue channel (6) with outflow openings (7). A valve and jet body (8) is in front of each outflow opening, with a sprung non-return valve (9), a glue channel (16) and a glue delivery opening (17).
Patent DE-502005010080-D1 (DE)
Inventor: IGNATYEV NIKOLAI MYKOLA
IPC: C07C209/84
Filed: 2005-06-17
Abstract: The invention relates to a process for the preparation of onium salts having a low chloride content by reaction of an onium chloride with an acid, where the hydrochloric acid forming is removed by azeotropic distillation by coordination to an organic solvent which forms an azeotropic mixture with water.
Patent DE-502005010334-D1 (DE)
Inventor: KNIEF HENNING
IPC: E01F8/02
Filed: 2005-03-15
Abstract: A filling space (15) is provided for arranging a wadding (14) e.g. soil excavation. Absorbing insulating layers (13) and carrier mats (12) are integrated in the filling space for holding the wadding. The wadding is arranged between the insulating layers and carrier mats. The insulating layers are comprised of a synthetic material, non-woven cloth made from natural fibers or artificial fiber fleece.
Patent DE-502006002637-D1 (DE)
Inventor: OSTERLOH KURT DR RER NAT
IPC: G21K1/00
Filed: 2006-10-06
Abstract: A focus orientating aperture for a high energy radiation beam from a source (16) comprises, an absorption cylinder (10) capable of periodic motion, e.g. axial rotation, and provided with one or more apertures (14), such that all radiation incident on the cylinder surface is absorbed, but a uni-directional ray (18) along the axis of the aperture is transmitted to an investigated sample or work surface. an INDEPENDENT CLAIM is included for a method of manufacturing a perforated absorption cylinder, particularly by the use of a high pressure (approx.3800 bar) water cutting jet. Dependent on the application, the absorption cylinder may comprise e.g. a cylindrical outer sheath of copper, tungsten, or heavy metal, with an inner core of polyethylene or boron. The collimation device can be used in the reverse sense to handle radiation scattered from a surface, with a detection element positioned at the focal point (16).
Patent DE-502006006377-D1 (DE)
Inventor: DINSER TORSTEN
IPC: A47C19/02
Filed: 2006-06-30
Abstract: The device has a bearing plate (4) that is firmly fixed at a place, and a bearing body (5) with a semi-circular bearing shell (5a). The bearing body has a bearing section (5b) on the opposite side of the shell to hold a bearing bolt in the shell. The section is fixed in a holding position when the bolt is radially clamped in the bearing body, such that the section counteracts the effect of spring forces that cause splaying.
Patent DE-502006006411-D1 (DE)
Inventor: GENSTER ALBERT
IPC: F04D29/54
Filed: 2006-10-10
Abstract: The invention relates to an electric fluid pump with a semi-axial construction, in which a motor housing part (9), situated at the pressure end, has a conduction device (42). The conduction device (42) allows an almost completely irrotational flow to be achieved so that the kinetic energy of the tangential component of the flow velocity is converted into pressure energy with negligible friction losses. This feature of the invention increases the efficiency of the fluid pump. The dimensions of the electric motor can therefore be reduced while maintaining the same delivery quantity.