baber/WOPTO huggingface dataset:
Patent CA-3104658-A1 (CA)
Inventor: HAN SEON-YOUNG
IPC: C07K14/00
Filed: 2019-08-05
Abstract: The present invention provides the peptide nucleic acid derivative which targets 5' splice site of the human ACC2 pre-mRNA "exon 12". The peptide nucleic acid derivatives in the present invention strongly induce splice variants of the human ACC2 mRNA in cell and are very useful to treat conditions or disorders of skin aging associated with the human ACC2 protein.
Patent CA-3105904-A1 (CA)
Title: Procede de soudage de pieces a base de materiau thermoplastique
Inventor: GLOTIN MICHEL
IPC: B29C65/32
Filed: 2019-07-16
Abstract: L'invention concerne en premier lieu un procédé de soudage d'au moins deux pièces (2, 3) comprenant un matériau thermoplastique et ayant des surfaces (10, 11) à souder respectives, comprenant : l'insertion d'un insert (4) entre les surfaces (10, 11) à souder des deux pièces (2, 3); la génération de chaleur par ledit insert (4); dans lequel l'insert (4) se déplace par rapport aux pièces (2, 3) à souder lors du soudage, selon une direction de soudage. L'invention concerne également une installation (1) adaptée pour la mise en oeuvre de ce procédé.
Patent CA-3108744-A1 (CA)
Inventor: ILAN EREZ
IPC: A61K47/10
Filed: 2019-08-08
Abstract: The present invention provides methods for large scale preparation of sterile stable liquid thrombin composition comprised of glycerol; stable liquid thrombin compositions; and hemostatic composition and kits. The present invention further provides hemostatic compositions comprised of liquid thrombin, glycerol and gelatin. Further provided herein is a method for the large-scale production of a sterile liquid thrombin composition comprised of glycerol.
Patent CA-3113996-A1 (CA)
Inventor: FARMER SEAN
IPC: A23K20/142
Filed: 2019-10-08
Abstract: The subject invention provides compositions and methods for reducing atmospheric methane and/or nitrous oxide emissions using livestock feed additives and/or supplements. In preferred embodiments, a composition comprising a beneficial microorganism and/or a growth by-product thereof is contacted with animal feed and/or drinking water prior to the animal ingesting it. The composition is capable of, for example, controlling methanogenic microorganisms within the animal's digestive system, and thus, reducing the amount of enteric methane emissions produced from the animal and from the animal's waste.
Patent CA-3116206-A1 (CA)
Inventor: SKINNER MICHAEL
IPC: B63C13/00
Filed: 2020-07-13
Abstract: There is disclosed herein systems and apparatuses for use with personal watercraft having a top side, a bottom side, a long axis, fore and aft sections and at least one passenger opening defined in the top side between the fore and aft sections, the systems and apparatuses including at least two legs each having a first end and second end, and each attachable at its first end to the watercraft and each having disposed at its second end a wheel; an inflatable bladder attachable to the watercraft; a compressor in fluid communication with the bladder; and a control unit for activating the compressor to inflate the bladder from a stowed configuration to a deployed configuration.
Patent CA-3116624-A1 (CA)
Inventor: VOLODARSKY ROGER
IPC: A24F47/00
Filed: 2019-09-06
Abstract: A portable vaporizing device and/or cartridge comprises a product chamber capable of holding a vaporizable product therein, and a porous valve element configured to be heated to flow the vaporizable product therethrough and generate vapor from the vaporizable product, and optionally including a heat transfer element to heat the vaporizable product as it flows through the product chamber towards the porous valve element.
Patent CA-3117843-A1 (CA)
Inventor: LIU MINGFEI
IPC: H01M8/124
Filed: 2019-10-30
Abstract: A method of forming a solid oxide fuel cell., including tape casting an anode support, an anode functional layer slurry comprising of NiO and ScCeSZ ceramic powder is coated onto the anode support and then dried to form an NiOScCeSZ anode functional layer on the anode support. A first electrolyte layer comprising of a ScCeSZ slurry is then coated onto the NiO-ScCeSZ functional layer and then dried to form a ScCeSZ electrolyte layer on the NiO-ScCeSZ functional layer. A second electrolyte layer comprising of a samarium doped CeO2 (SDC) slurry is then coated onto the ScCeSZ electrolyte layer and then dried to form a SDC electrolyte layer on the ScCeSZ electrolyte layer. The combined layers are then sintered. A cathode slurry is then coated onto the SDC electrolyte layer and then sintered to form a solid oxide fuel cell.
Patent CA-3117937-A1 (CA)
Inventor: OSTERHUS STEIN WOLD
IPC: A01K61/60
Filed: 2019-10-25
Abstract: An offshore farming system comprising an elongated vertical support column (200) floating vertically in water with a larger extension below sea surface (10) than above the sea surface (10), and a rigid cage structure (300) enclosing the elongated vertical support column (200)in circumferential direction and arranged movable in longitudinal direction of the elongated vertical support column (200).
Patent CA-3118749-A1 (CA)
Inventor: FRIEBERG DAN
IPC: G06Q10/06
Filed: 2019-11-07
Abstract: A system to receive data representing agronomic responses based on randomized replicated treatments conducted in test plots of agronomic environments, aggregate the data representing the agronomic responses into subsets of the data representing the agronomic responses, each subset of the data representing the agronomic responses associated with one of a number of performance zones, receive characteristics associated with a portion of a field and determine that the portion of the field represents a particular performance zone of the number of performance zones based on the characteristics associated with the portion of the field, recommend a particularized treatment level for a crop located in the portion of the field based on the particular performance zone, and communicate the particularized treatment level to a machine, the particularized treatment level to be applied to the portion of the field by the machine to optimize an agronomic response based on the particular performance zone.
Patent CA-3118752-A1 (CA)
Title: Composes bicycliques
Inventor: KONRADI ANDREI W
IPC: C07C311/16
Filed: 2019-11-07
Abstract: La présente invention concerne des composés et des compositions pharmaceutiques comprenant lesdits composés qui sont utiles pour le traitement de cancers. Des cancers spécifiques comprennent ceux qui sont médiés par YAP/TAZ ou ceux qui sont modulés par l'interaction entre YAP/TAZ et TEAD.
Patent CA-3118923-A1 (CA)
Inventor: PAPADOPOULOS VASSILIOS
IPC: A61K47/60
Filed: 2019-11-04
Abstract: The present disclosure concerns peptide compounds of formula (I) or (II) and combinations thereof that can be administered orally for promoting endogenous steroid, and particularly testosterone, production: A-Xaa1Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-Xaa8-B (I) A-Xaa1-XaaA-XaaB-Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-XaaC-XaaD-XaaE-Xaa8-B (II)
Patent CA-3119327-A1 (CA)
Title: Systeme et methodologie de gestion de construction et de positionnement d'equipement au moyen d'une modelisation d'informations de construction
Inventor: FUGALLO JOSEPH A
IPC: H04B5/00
Filed: 2019-11-09
Abstract: L'invention concerne un système, un procédé et un appareil consistant à : générer un modèle de construction d'un bâtiment à construire sur un site de construction ; identifier, dans le modèle du bâtiment, des emplacements de position pour l'installation d'un ou de plusieurs appareils d'ancrage dans les éléments structurels du modèle de construction ; transmettre le modèle de construction à un dispositif informatique portable sur le site de construction ; et identifier l'emplacement du dispositif informatique portable à un emplacement de position donné. Au moins les étapes de génération, d'identification, de transmission et d'identification sont mises en uvre au moyen d'au moins un dispositif de traitement comprenant un processeur et une mémoire.
Patent CA-3120847-A1 (CA)
Title: Devices, methods, and systems for installation of photovoltaic systems
Inventor: TOMLINSON JOSEPH
IPC: H01R4/64
Filed: 2019-10-23
Abstract: Devices, methods, and systems for installing photovoltaic systems are provided that are simple and easy to install, and that minimize the number of separate components or parts needed. Such devices, methods, and systems ensure seamless mechanical and electrical connectivity by their design, and minimize the time and effort expended by tradespersons or other technicians, especially in dangerous environments.
Patent CA-3122075-A1 (CA)
Title: Graft system
Inventor: VISSER ANTHONY
IPC: A01G2/32
Filed: 2019-12-03
Abstract: The present disclosure relates to a graft system configured to graft plant material, comprising: a first holder (12) configured to engage a stem (9) of a first plant (10), below a cut line (21) to hold a severed stem (9) and connected roots of the first plant (10); and a second holder (12) configured to engage a stem (9) of a second plant (10), above a cut line (22) to hold a severed stem (9) and connected leafs of the second plant (10); wherein the second holder (12) is stackable on the first holder (12), to thereby abut and align the severed stems (9). In addition, the present disclosure relates to a strip (1, 6) embodying a graft system (30) as well as an assembly of a strip (1, 6) or graft system (30) with a tray (5).
Patent CA-3122360-A1 (CA)
Inventor: THOMPSON DARYL L
IPC: A61K31/085
Filed: 2019-12-03
Abstract: A composition comprises ß-pinene, bomeol, cinnamic aldehyde, citral, d-limonene, eucalyptol, eugenol, famesol, linalool, thymol, and vanillin. In addition, a method for use of the composition as an antibacterial and antiviral agent is also disclosed.
Patent CA-3123732-A1 (CA)
Title: Nouveau derive d'isoquinoline, methode de preparation et composition pharmaceutique pour prevenir ou traiter les maladies liees a l'autophagie contenant le derive comme ingredient actif
Inventor: BAE MYUNG-AE
IPC: A61K31/472
Filed: 2021-06-30
Abstract: Il est décrit de nouveaux dérivés d'isoquinoline de formule 1 <DIG> dans lesquels X, Y, Z et R1 peuvent représenter diverses entités chimiques. Les dérivés disoquinoline peuvent être utilisés pour prévenir ou traiter les maladies liées à lautophagie contenant ces premiers. Les dérivés disoquinoline peuvent également être utilisés pour réguler les activités dautophagie, et, par conséquent, en utilisant ces dérivés, un effet utile peut être utilisé comme composition pharmaceutique pour prévenir ou traiter les maladies liées à lautophagie, comme les maladies neurodégénératives, les maladies inflammatoires, les maladies liées à la mélanogenèse, les troubles métaboliques, le cancer, une composition daliment ayant un effet sur la santé aux fins damélioration de ce qui précède, ou une composition cosmétique avec une fonction de blanchiment. Il est également décrit des procédés de préparation et des compositions pharmaceutiques liées aux dérivés disoquinoline.
Patent CA-3128476-A1 (CA)
Inventor: BLAKE TIM R
IPC: A61K47/69
Filed: 2020-01-31
Abstract: There are provided herein, inter alia, complexes, compositions and methods for the delivery of therapeutic, diagnostic and imaging agents, including nucleic acid, into a cell. The complexes, compositions and methods may facilitate complexation, protection, delivery and release of oligonucleotides and polyanionic cargos into lung cells and lung tissue, both in vitro and in vivo.
Patent CA-3131573-A1 (CA)
Inventor: KLAPPROTH HOLGER
IPC: G01N33/543
Filed: 2019-03-01
Abstract: In a flow cytometry measurement method, an analysis medium is provided, which comprises a fluid and biological cells contained therein. A labeling molecule is provided and is brought in contact with the analysis medium in such a way that the labeling molecule can bind specifically to a target structure located on the surface of the cell if the cell has said cell structure. For the individual cells, flow cytometry measured values are captured for a first and a second physical parameter. The first parameter is fluorescence radiation emitted by the labeling molecule when the labeling molecule is excited. The cells are classified on the basis of the flow cytometry measured values. A first calibrator and a second calibrator are provided, which have solid particles matching in shape, size and material. A target structure matching the target structure of the cells is immobilized on the surface of the first calibrator. The second calibrator does not have said target structure. The calibrators are mixed with the analysis medium before the flow cytometry measured values are captured. Corresponding first and second flow cytometry measured values are captured for the calibrators as well as for the cells. A normalized first flow cytometry measured value for the cell is formed from the first flow cytometry measured value of the first calibrator, the first flow cytometry measured value of the second calibrator and the first flow cytometry measured value of the cell.
Patent CA-3133593-A1 (CA)
Inventor: PARPAJOLA VLADI
IPC: G01D5/347
Filed: 2020-03-13
Abstract: A linear encoder (1) for numeric-control machine tools of the type comprising: a substantially rectilinear section-bar (2), which is adapted to be fixed on the structure of the machine tool; a substantially rectilinear scale strip (3), which is fixed on the section-bar (2) so as to extend along the section-bar (2) parallel to the section-bar longitudinal axis (L); a movable slider (4) which is fitted/mounted on the section-bar (2) so as to be able to move along the section-bar parallel to the section-bar longitudinal axis (L) and skimming the scale strip (3), and which is adapted to be rigidly fixed to the movable piece of the machine tool; an electronic reading apparatus (5) which is at least partially placed aboard the movable slider (4) and is adapted to read the position of the movable slider (4) on the scale strip (3); and finally a thermal-stabilization device (20) which is adapted to bring and maintain substantially the whole scale strip (3) stably at a predetermined target temperature (T0).
Patent CA-3134161-A1 (CA)
Title: Arrangement for securing a panel in a rail by tightening outer wedges from an inner side of the panel
Inventor: GIACOMETTI SYLVIANE
IPC: E04F11/18
Filed: 2020-05-25
Abstract: The invention relates to an arrangement for securing a vertical panel (14) in a longitudinal groove (28), the panel (14) comprising an inner face (20) and an outer face (22), the securing being carried out by transverse clamping between transversely opposed wedges (36A, 36B; 38A, 38B), the arrangement comprising: - an upper outer wedge (38A) and a lower outer wedge (38B) which are each positioned between an outer face (34) of the groove (28) and the outer vertical face (22) of the panel (14); - at least two movable transmission members (62A, 62B) which are each capable of transmitting a sliding force to an associated outer wedge (38A, 38B), the force being applied from an inner side (24) of the panel (14); the arrangement is characterised in that the upper and lower outer wedges (38A, 38B) slide vertically upwards from the released position thereof to the clamped position thereof above the released position.
Patent CA-3134187-A1 (CA)
Inventor: COHEN EDWARD AARON
IPC: A61F9/00
Filed: 2020-03-20
Abstract: An implantable ocular drug delivery system can include inserting an implantable device into an eye, where the device contains therapeutics intended to be released for local or systemic effects. In some implantable device embodiments, the device includes a microchannel intended to reduce intraocular pressure. In some implantable device embodiments, the device includes a microchannel intended to treat dry eye.
Patent CA-3137110-A1 (CA)
Title: Bimodal poly(ethylene-co-1-alkene) copolymer
Inventor: ASKAR SHADID
IPC: C08F210/16
Filed: 2020-04-28
Abstract: A bimodal poly(ethylene-co-1-alkene) copolymer comprising a higher molecular weight poly(ethylene-co-1-alkene) copolymer component and a lower molecular weight poly(ethylene-co-1-alkene) copolymer component. The copolymer is characterized by a unique combination of features comprising, or reflected in, its density; molecular weight distributions; component weight fraction amount; viscoelastic properties; and environmental stress-cracking resistance. Additional inventive embodiments include a method of making the copolymer, a formulation comprising the copolymer and at least one additive that is different than the copolymer, a method of making a manufactured article from the copolymer or formulation; the manufactured article made thereby, and use of the manufactured article.
Patent CA-3140276-A1 (CA)
Title: Hvdc power cable with water-blocking capability
Inventor: GUSTAFSSON KRISTIAN
IPC: H01B7/14
Filed: 2020-05-20
Abstract: A high voltage DC power cable (1-1) designed for voltages of 320 kV or higher, comprising: a multi-wire conductor (3), an inner semiconducting layer (5) arranged around the multi-wire conductor (3), the inner semiconducting layer (5) forming a screen layer for the multi-wire conductor (3), a solid insulation system (7) arranged around the inner semiconducting layer (5), and a water-blocking compound (15) configured to restrict water migration into the high voltage DC power cable (1-1).
Patent CA-3140372-A1 (CA)
Inventor: REID TYLER GERALD RENE
IPC: G01S19/07
Filed: 2020-03-09
Abstract: Un satellite en orbite basse (LEO) comprend un récepteur de positionnement global configuré pour recevoir une première signalisation provenant d'une première pluralité de satellites de navigation autre que LEO. Un émetteur-récepteur intersatellite est configuré pour envoyer et recevoir des communications intersatellites avec d'autres satellites de navigation LEO. Au moins un processeur est configuré pour exécuter des instructions opérationnelles qui amènent le ou les processeurs à effectuer des opérations qui comprennent : la détermination d'une position orbitale du satellite LEO sur la base de la première signalisation ; et la génération d'un message de navigation sur la base de la position orbitale. Un émetteur de signal de navigation est configuré pour diffuser le message de navigation à au moins un dispositif client, le message de navigation facilitant au ou aux dispositifs clients la détermination d'une position améliorée du ou des dispositifs clients sur la base du message de navigation et en outre sur la base d'une seconde signalisation reçue d'une seconde pluralité de satellites de navigation autres que LEO.
Patent CA-3140696-A1 (CA)
Inventor: WANG GUOFENG
IPC: G06Q30/00
Filed: 2021-11-30
Abstract: A method, an apparatus, a computer device, and a storage medium for category prediction of merchandise are disclosed. The method involves: acquiring merchandise information data under all merchandise groups together with user behavior data, preprocessing the merchandise information data and the user behavior data, performing statistical analysis on a plurality of merchandise indicators; according to the merchandise indicators, extracting a plurality sets of merchandise features, wherein the sets of merchandise features at least include frequency features, cover features, and click features; selecting the frequency features, the cover feature, and the click features to construct merchandise group indexes; receiving and analyzing search information, and according to the merchandise group indexes, outputting category candidate sets corresponding to the search information. The method is constructed on various features and uses text information features, user behavior features, and features of the merchandise groups themselves to realize category prediction, thereby enhancing accuracy of search results.
Patent CA-3143111-A1 (CA)
Inventor: MITAS PETR
IPC: C07D233/86
Filed: 2020-06-25
Abstract: La présente invention porte sur un procédé pour la préparation d'enzalutamide, d'un composé (1) ou d'un sel ou d'un solvate de celui-ci : formule (1). La présente invention concerne également un solvate de 1,4-dioxane du composé (1).
Patent CA-3144842-A1 (CA)
Title: Methods to employ concatenation in asr service usage
Inventor: AHER ANKUR ANIL
IPC: G10L15/30
Filed: 2019-12-20
Abstract: Systems and methods for processing audio streams are disclosed herein. In a disclosed method, N number of audio streams is received from an independent source, each audio stream includes speech content. A set of the N audio streams is concatenated to generate a concatenated audio stream. Based on the N received audio streams or the set of audio streams, N-1 or one less that the total number of audio streams in the set of audio stream separators, respectively, are generated. An audio stream separator is inserted between every two adjacent audio streams of the concatenated audio stream to generate a single audio stream payload. The single audio stream payload is transmitted for transcription of the audio stream speech content to text content and in response to transmitting the payload, a text file is received including text content corresponding to the audio streams delineated by the audio stream separators.
Patent CA-3148444-A1 (CA)
Title: Ezh2 inhibition in combination therapies for the treatment of cancers
Inventor: BRADLEY WILLIAM D
IPC: A61K33/243
Filed: 2020-07-23
Abstract: Provided herein are methods for treating advanced relapsed solid tumors using 7- chloro-2-(4-(3-methoxyazetidin-1-yl)cyclohexyl)-2, 4-dimethyl -N-((6-methyl-4-(methylthio)- 2-oxo-l,2-dihydropyridin-3-yl)methyl)benzo[d][l,3]dioxole-5-carboxamide; or a pharmaceutically acceptable salt thereof. Also provided herein are methods of treating cancers (e.g., solid tumors) using 7-chloro-2-(4-(3-methoxyazetidin-l-yl)cyclohexyl)-2,4- dimethyl-N-((6-methyl-4-(methylthio)-2-oxo-l,2-dihydropyri din-3- yl)methyl)benzo[d][1,3]dioxole-5-carboxamide; or a pharmaceutically acceptable salt thereof; and a second agent selected from a topoisomerase inhibitor, a DNA alkylating agent, and an androgen receptor signaling inhibitor.
Patent CA-3150664-A1 (CA)
Inventor: HUNT ANDREW
IPC: B63B21/26
Filed: 2020-08-11
Abstract: La présente invention concerne un dispositif de fixation allongé (1) destiné à être utilisé dans un ancrage sous-marin, et un procédé d'installation. Le dispositif (1) a un agencement de tige à triple emboîtement, la tige la plus à l'intérieur (2) ayant un dispositif de coupe (9) disposé au niveau d'une extrémité distale et une section conique (8) située de façon adjacente et de façon proximale derrière le dispositif de coupe (9). Une tige intermédiaire (3) entoure au moins une partie centrale de la tige interne (2) et a un ou plusieurs doigts de coupe pouvant s'évaser (7) au niveau de son extrémité distale. Une tige externe (4) entoure une partie proximale de la tige intermédiaire (3). Les tiges interne (2) et intermédiaire (3) sont couplées par un premier couplage mobile (17) qui, lorsqu'il est libéré, permet un mouvement axial relatif le long d'une première distance. Les tiges externe et intermédiaire sont couplées par un second couplage mobile (18) qui, lorsqu'il est libéré, permet un mouvement axial relatif le long d'une seconde distance. La tige intermédiaire (3) est emboîtée à l'intérieur de la tige externe (4), dans certains cas pour au moins une majorité de la tige externe (4). Dans certains exemples, la tige externe (4) a une partie pouvant être entraînée en rotation (10) et la tige interne (2) a un écrou de tension (12) pour ajuster les positions axiales relatives des tiges interne (2) et externe (4). L'écrou de tension (12) et la partie pouvant être entraînée (10) peuvent être couplés à un seul entraînement rotatif (23). L'invention concerne également un procédé d'installation et un appareil d'installation (21).