baber/WOPTO huggingface dataset:
Patent EC-SP034893-A (EC)
Title: Inhibidores de proteasa vih, composiciones que los contienen, sus usos farmaceuticos y materiales para su síntesis
Inventor: BARVIAN MARK ROBERT
IPC: A61K/
Filed: 2003-12-11
Abstract: Un compuesto que tiene la fórmula I: donde: R1es un grupo monociclico, carbocíclico o heterocíclico, de 5-o6- miembros, donde dicho grupo carbocíclico o heterocíclico es saturado, parcialmente insaturado o totalmente insaturado y es no sustituido o sustituido por uno o más sustituyentes adecuados; R2 es un grupo alquilo sustituido, un grupo alquenilo no sutituido o sustituido, un grupo alquinilo no sustituido o sustituido, un grupo fenil sustituido, un grupo fenilalquil sustituido, un grupo fenilalquil no sustituido o sustituido, o un grupo fenilalquinil no sutituido o sustituido; R2' es H o un grupo alquil C1-C4 no sustituido o sustituido; donde Rx es H o más sustituyentes adecuados; Z es S, O, SO, SO2, CH2, o CFH: R3 es H o un grupo alquil C1-C4, no sustituido o sustituido; R4, R5, R6 y R7 se seleccionan independientemente de H o un grupo alquilo C1-C6, y R8 y R8? se seleccionan independientemente de H, halo, un grupo alifático C1-C4, o un grupo alifático halo sustituido C1-C4. Donde cualquiera de dichos sustituyentes grupos alquil, alquenil, alquinil se sustituyen por uno o más sustituyentes adecuados. Con la condición de que dicho grupo monocíclico, heterocicloalquil, geterocicloalquenil, o heteroaril de 5 - o 6- miembros congenga al menos dos heteroátomos cuando R2 sea un grupo fenil sustituido, un grupo fenilalquil sustituido, un grupo fenilalquenil no sustituido o sustituido, o un grupo fenilalquinil no sustituido o sustituido, o Con la condición de que dicha proción alquil, alquenil, o alquinil de dicho grupo fenilalquil, fenilalquenil o fenilalquinil sustituido, sea sustituida por uno o más sustituyentes adecuados seleccionados de halo o ceto, o, fenilalquinil sustituido sea sustituida por uno o más sustituyentes adecuados que no sean halo o metil; O una prodroga, sal farmacéuticamente aceptable, metabolito farmacéuticamente activo, o solvato farmacéuticamente aceptable del mismo.
Patent EC-SP045453-A (EC)
Title: Método de recubrimiento de una superficie de hormigón
Inventor: HISASHI OSAMU
IPC: C04B41/46
Filed: 2004-11-25
Abstract: Método para mejorar la adhesividad entre composiciones de cemento endurecido y materiales de recubrimiento de resina rociando una solución acuosa que contiene uno o más ácidos orgánicos, los cuales reaccionan con la superficie para producir compuestos de calcio en la superficie de cemento endurecido, antes de aplicarse el material de recubrimiento de resina, eliminando así la membrana de carbonato de las composiciones de cemento hidratado. Esto mejora la adhesividad entre las composiciones de cemento endurecido y el material de recubrimiento de resina.
Patent EC-SP055602-A (EC)
Inventor: ANGELSKAAR TERJE
IPC: B65G53/38
Filed: 2005-02-15
Abstract: A method of lubrication of the passage of a cementitious composition through a conduit, comprising the addition to the conduit prior to addition thereto of the cementitious composition of an aqueous solution of a solid lubricating composition consisting essentially of (i) an alkali metal carbonate or bicarbonate, (ii) poly(ethylene oxide), and (iii) anionic sulphate surfactant. The use of this composition allows the convenient achievement of flow, without the necessity to mix sometimes substantial quantities of cement slurry in situ.
Patent EC-SP099734-A (EC)
Title: Composición farmaceutica que comprende la combinación de un agente antiinflamatorio no esteroideo y un agente anticonvulsivante
Inventor: SANTOS MURILLO JOSEFINA
IPC: A61K31/197
Filed: 2009-11-13
Abstract: La presente invención está relacionada con una composición farmacéutica compuesta por la combinación sinérgica de un agente anticonvulsivante, como lo es el principio activo: Gabapentina y un agente antiinflamatorio no esteroideo, como lo es el principio activo: Meloxicam, los cuales se encuentran formulados en una sola unidad de dosificación para ser administrada por vía oral, misma que está indicada para el tratamiento del Dolor Neuropático provocado por diversas etiologías.
Patent EC-SP104578-A (EC)
Title: Derivados de indolilmaleimida como inhibidores de proteína de cinasa c
Inventor: EVENOU JEAN PIERRE
IPC: A61P21/00
Filed: 2010-03-11
Abstract: Los derivados de indolilmaleimida que comprenden un residuo de fenilo sustituido, naftilo, tetrahidronaftilo, quinazolinilo, quinolilo, isoquinolilo, o pirimidinilo, tienen interesantes propiedades farmacéuticas, por ejemplo en el tratamiento y/o en la prevención de enfermedades o desórdenes inflamatorios agudos o crónicos mediados por células T, enfermedades autoinmunes, rechazo de injertos, o cáncer.
Patent EC-SP982523-A (EC)
Title: Sal tartrato de un dipeptido sustituido
Inventor: LEFKER BRUCE ALLEN
IPC: C07D211/00
Filed: 1998-06-08
Abstract: Esta invención se refiere a la sal de ácido (L)-tartárico o de la 2-amino-N-{1-2,4-difluoro-benciloximetil)-2-oxo-2- [3-oxo-3a-piridin -2-ilmetil-2-(2,2,2-trifluoro-etil)-2,3,3aA, 6,7-hexahidro-pirazolo [4,3-c] piridin -5-il] etil}-2-metil-propionamida, la cual es un secretagogo de la hormona de crecimiento endógena. En otro aspecto, esta invención proporciona determinados productos intermedios que son útiles para la síntesis del compuesto anterior. La sal del ácido (L)-tartárico del compuesto de está invención es útil para el tratamiento y/o prevención de la osteoporosis, resistencia a la insulina y otros trastornos o enfermedades asociadas con la diferencia de hormona del crecimiento. La sal del ácido (L)-tartárico del compuesto de la presente invención es también útil para el tratamiento de la osteoporosis cuando se usa en combinación con: un compuesto bisfosfonato, estrógenos, Premarin y opcionalmente progesterona, un agonista o antagonista de estrógenos o calcitonina. Además,la presente invención se refiere a procedimientos que comprenden la administración de un agonista alfa-2-adrenérgico y de la sal del ácido (L)-tartárico del compuesto de esta invención.
Patent FI-20175234-A (FI)
Title: An instrument product and a method for manufacturing the same
Inventor: LENTO JAAKKO
IPC: A61C3/00
Filed: 2017-03-16
Abstract: An instrument product comprises a medical hand instrument (101) and a radio frequency identifier (102) readable from a distance away from the radio frequency identifier. The radio frequency identifier is at least partly covered with cover material (103) attached with adhesive material to a surface of the medical hand instrument so that the adhesive material is in contact with both the cover material and the surface of the medical hand instrument. The cover material can be the same material as the adhesive material, or the cover material may constitute a cover element which comprises a cavity for the radio frequency identifier and which is attached with the adhesive material to the surface of the medical hand instrument.
Patent GB-1051546-A (GB)
IPC: F23D11/10
Abstract: 1,051,546. Burners. GULF RESEARCH & DEVELOPMENT CO. Aug. 4, 1964 [July 31, 1963; March 20, 1964], No. 31067/64. Heading F4T. An oil spray nozzle has a central fuel conduit 62 leading by swirl grooves 32 into a swirlchamber 30 and thence to the spray outlet 36. Air is aspirated through the ports 56 and swirl grooves 44 and has to pass over a sharp edge 42 before passing out through the outlet 48. The grooves 44 may be arcuate and the air aspirated direct from inlets adjacent the nuzzle outlet and the grooves may be omitted, the air being drawn into a chamber surrounding the conical end of part 14.
Patent GB-1052944-A (GB)
IPC: F28D13/00
Abstract: 1,052,944. Agitating by gas currents. J. S. M. BOTTERILL and J. R. WILLIAMS. Oct. 7, 1963 [July 6, 1962], No. 25953/62. Heading B1C. [Also in Division F4] A method of improving heat transfer between a fluidized bed and a surface in contact therewith comprises causing a displacement member such as a scraper 7 to continually or repeatedly sweep over the surface in close proximity thereto. In the apparatus shown the fluidized bed is contained in the annular space between cylindrical walls 2, 3 and acts as a heat transfer medium to effect heat exchange between one fluid flowing within the space defined by the wall 2 and another fluid flowing over the outside of the wall 3. Fluidizing gas is supplied to the bed through a porous plate 4. The scraper blades 7 are carried on an arm 6 mounted on a rotary shaft 5 and may be shaped to induce a rotary motion of the particles. Stirring devices (not shown) for the middle portion of the bed may be carried on the arms 6 supporting the scrapers 7. The invention is said to be applicable to fluidized beds (including catalyst beds) in chemical reactions and to adsorption towers and mass transfer columns.
Patent GB-1054429-A (GB)
IPC: B01D1/22
Abstract: 1,054,429. Plate-type evaporators. A.P.V. CO Ltd. Nov. 11, 1965 [Dec. 10, 1964] No. 50391/64. Heading BIB. [Also in Division F4] In a plate-type evaporator, there are provided, in the same frame as the plates of the evaporator section, additional plates between which the liquid-to-be-evaporated is preheated with part of the heating vapour fed to the evaporator section. The apparatus shown comprises a triple-effect plate evaporator A, B, C, and a plate condenser D. Effect B is provided with a preheater stage R; and effect C and condenser D have preheater stages Q and K, respectively. The feed liquid is pumped first through stage K and subsequently through stages Q and R. The preheated feed is then introduced into effect A, which is supplied with live steam. The process vapours separated in separator A' are used as heating medium in effect B. The process vapours produced in effect B are used as heating-medium for effect C. The vapours from effect C are passed to condenser D.
Patent GB-1054546-A (GB)
IPC: B42F17/28
Abstract: 1,054,546. Filing papers &c. ROTADEX SYSTEMS Ltd., and MAGNOID (BRISTOL) Ltd. Oct. 30, 1963 [Oct. 30, 1962], No. 40990/62. Heading B6E. A card index comprises a table 4 having several slots in its upper surface to expose index cards 10 which are removably mounted on endless flexible belts 2 mounted on rollers beneath the table, each belt having integral therewith, or secured thereto, a pair of parallel strips 11, Fig. 3 (not shown), of inverted T-form, and the cards 10 are slotted to engage over the strips 11. The strips 11 may be of polythene or polyvinyl chloride, and the head portions 14 thereon are semi-circular in cross-section, and they engage in substantially square slots 15 in the cards 10. Dividing strips or compactors 17 are secured by rivets at intervals along each belt 2. Pockets may be mounted on each belt to receive unslotted cards. Each belt 2 is supported horizontally on rollers 5 and passes around a roller 6 which is spring mounted and adjustable. Each belt is geared to a motor 7 controlled by a foot pedal 8.
Patent GB-1143820-A (GB)
IPC: A47C27/08
Abstract: 1,143,820. Repairing apertures in inflatable articles. R. F. D. CO. Ltd. 14 Sept., 1967 [4 Oct., 1966], No. 44321/66. Heading B7C. A method of filling an aperture in an inflatable article of composite fabric, i.e., a material comprising two superimposed layers of fabric which are tied together by retaining threads for the purpose of preventing separation of the two layers beyond a predetermined amount upon inflation of the article, comprises the steps of trimming the aperture so that it defines a rectangular shaped hole through the article with two opposed sides of the hole parallel with the direction in which the retaining threads are woven, introducing into the hole an inflatable section of composite fabric having characteristics similar to those of the fabric of which the article is formed and of the same size and shape as said hole, and joining by means of sealing strips the outer surfaces of the section to the outer surfaces of the fabric surrounding the hole. As shown, a rectangular shaped hole in a lifting bag 1 is about to be filled with a section 15 of composite fabric, which is preferably cut so that the direction in which the retaining threads 3 are woven is transverse to the direction in which the retaining threads in the surrounding composite fabric are woven. At two opposed ends of the hole, flaps 11 formed from the top and bottom layers of the fabric are folded inwardly and secured together by a sealing strip 13. Opposed sides of section 15 which are to be adjacent the unsealed sides of the hole in the inserted condition are sealed by flaps 16, 17 and sealing strip 18 in a similar manner. Instead of using sealing strips, the flaps may be made to overlap and may be adhesively secured to each other. If desired, the ends of section 15 may be sealed by fabric panels 19. Section 15 is secured in its inserted condition by sticking strips over the joints between the section and the remainder of the bag. A valve is then fitted to the section to enable it to be inflated or deflated with the remainder of the bag. In modifications, a tube from a main air valve for the article may be arranged to communicate with the interior of the section or a port may be formed to place the interior of the section in communication with the interior of the article so that the section will inflate and deflate automatically with the article itself.
Patent GB-1225535-A (GB)
IPC: B29C61/00
Filed: 1968-10-14
Abstract: 1,225,535. Covering bores by winding. GOLDSWORTHY ENG. Inc. 14 Oct., 1968 [12 Oct., 1967], No. 48635/68. Heading B8G. [Also in Division D1] Apparatus for producing a filament reinforced product comprises a tank 6 containing resin through which the strands of filament pass. A flexible plastics film 51 drawn off from reel 50 is wrapped round the impregnated filament in the vacuum chamber 25 by means of the forming tube 30. Ultrasonic sealing device 38 seals the longitudinal margins of the plastics sheet which then passes through a shrinking zone 62 which has a heater 64 which causes the film 51 to shrink.
Patent GB-1250993-A (GB)
IPC: H03M5/16
Filed: 1969-01-10
Abstract: 1,250,993. Digital transmission systems. PHILIPS ELECTRONIC & ASSOCIATED INDUSTRIES Ltd. 10 Jan., 1969 [13 Jan., 1968], No. 1562/69. Addition to 1,132,274. Heading H4P. A transmitter in a system as claimed in Specification 1,132,274 comprises a number m of channels. A pulse signal to be transmitted is applied to all the channels in parallel. Each channel comprises serially-connected first and second amplitude modulators with an interposed single sideband filter. All the first modulators are fed by a frequency equal to one quarter of the pulse rate b, and all the second modulators by a carrier frequency f. The frequencies fed to the modulators in any one channel are shifted by 180 degrees/m relative to the adjacent channel. The cut-off frequency of the side-band filter is determined only by the bit rate. In one embodiment, Fig. 1, binary pulses at rate b from source 1 pass to modulo-2 adder 8 which feeds subtractor 5 and delay 6. Delay 6 has a period of two bits, i.e. 2/b, and feeds both adder 8 and subtractor 5. The signal from subtracter 5 has zeroes in the amplitude/ frequency characteristic at frequencies nb/2, and passes to filter 9 which passes only those frequencies below about b/2. The filter output feeds the m channels: here m = 2. The channels include ring modulators 13, 14 which are fed by signals of frequency b/4 which are 90 degrees apart. Filters 15, 16 having a cut-off frequency b/4, select the lower side-bands and pass them to amplitude modulators 18, 19. Pilot signals of frequency b/4 and 90 degrees apart are added at 23, 24. Modulators 18, 19 are fed by carrier frequencies f, 90 degrees apart, and their outputs are added at 20, a pilot signal of frequency f - b/4, derived by mixer 25 and filter 26, being added to the sum prior to transmission, the sum already containing a pilot frequency f + b/4. In a modification of Fig. 1, Fig. 3 (not shown), delay 6 has a period of four bits, i.e. nb/4, and the signal from subtractor 5 has zeroes at nb/4. In this case there is a zero at frequency f in the amplitude/frequency spectrum of the output of adder 20 so instead of adding at 28 a pilot frequency f - b/4 a frequency f is added.
Patent GB-1251706-A (GB)
IPC: H03D7/12
Filed: 1969-05-09
Abstract: 1,251,706. Transistor superheterodyne mixing circuits. RCA CORPORATION. 9 May, 1969 [16 May, 1968], No. 23719/69. Heading H3T. The two transistors of a cascode mixer for a superheterodyne receiver are located in different modules and are coupled by a transmission line. As shown, one module includes the R.F. amplifier, local oscillator and the common emitter stage 24 of the cascode circuit and the other transistor 26 is located in the I.F. module, the two modules being coupled by a coaxial cable 68 matched at the R.F. module end by a resistor and capacitor 70, 72 or, as in Fig. 6, not shown, by the load resistor of transistor 24. In the latter arrangement the two transistors are connected to the power supply in parallel. Feedback via a capacitor between the output collector and input have to improve heat rejection.
Patent GB-1252064-A (GB)
IPC: B01J39/08
Filed: 1969-03-20
Abstract: 1,252,064. Zeolitic phosphates and arsenates of iron and aluminium, and double salts thereof. TAKEDA YAKUHIN KOGYO K.K. 20 March, 1969 [20 March, 1968; 10 April, 1968; 25 July, 1968], No. 14596/69. Heading C1A. A desired metallic cation is recovered from a solution containing it by passing the solution through a zeolitic material of formula wherein M represents a univalent or half a bivalent cation and x, y and z are numbers with values 0#x#5 ; 0#y#1 ; z#9 and 0#l#1 respectively, when the cations M are substituted by the desired cation which may then be obtained by washing the exchanged zeolite material with an acid to recover the desired cations. The desired metallic cation may be Ag<SP>+</SP>, and the acid used nitric acid. The pH of the solution containing the desired metal ions may be 0À5 to 9, and the contacting with the zeolite and its subsequent washing may be effected at 50-100‹ C. The pH of the acid wash may be below 0À5. The zeolite employed may be synthesized by dissolving the sources of Al, Fe, P and/or As in water with the ranges (expressed in terms of the molar ratios of their oxides) sources of Na and/or K being dissolved therein so that (K, Na) 2 O/(Al, Fe) 2 O 3 >0À12 adjusting the pH of the resulting solution to the range in the appropriate one of the accompanying Figs. 1-4 (not shown) and heating at a temperature from 100‹ to 350‹ C. until crystals separate, usually 0À5 to a few hours, the conditions being such that solvent is not lost from the reaction system e.g. performing the reaction in a closed vessel. The crystals produced may be separated by filtration and used in the process of the invention.
Patent GB-1258559-A (GB)
IPC: C08J3/00
Filed: 1970-12-02
Abstract: 1,258,559. Thermosetting pulverulent binder; foundry mould composition. RHEINPREUSSEN A.G. 2 Dec., 1970 [12 Dec., 1969], No. 57299/70. Headings C3N and C3R. A thermosetting pulverulent. binder composition comprises a pulverulent mixture of a phenol-formaldehyde novolak and hexamethylene-tetramine, from 3-15% wt. MgO and 1-6% wt. of a mineral oil having a viscosity of from 12 to 30 E. at 20 C. It is made by fluidizing the mixture of novolak and (CH 2 ) 6 N 4  with pulverulent MgO and spraying the fluidized bed with the mineral oil. Uses.-The binder can be used for making a  free-flowing moulding composition, by mixing with a silica sand for example, for the manufacture of foundry moulds and cores.
Patent GB-1264407-A (GB)
IPC: C09B55/00
Filed: 1969-05-23
Abstract: 1,264,407. Pigmented coating. CIBA-GEIGY (UK) Ltd. 22 May, 1970 [23 May, 1969], No. 26503/69. Heading B2E. [Also in Divisions C3 and C4] Azomethine pigments of the general formula wherein X represents from 1 to 3 substituents which may be different and are hydrogen, halogen, nitro, amido, arylcarbamoyl, sulphamoyl, alkylsulphonamido, alkoxy, alkylamino or alkyl and Y represents from 1 to 3 substituents which may be different and are halogen, alkoxy or nitro or an aryl azo group and may be hydrogen when X is not hydrogen are incorporated in Example 18 into storing lacquers containing a carbamate resin, a coconut glycol alkyd resin of the non drying type in solution in xylene and 2-methoxyethanol, applied to cardboard and stoved at 120‹C for 30 minutes.
Patent GB-1266252-A (GB)
Inventor: JACKSON B G
IPC: C07D/
Filed: 1970-03-10
Abstract: 1,266,252. Preparing 3-methyl-7-aminocephalosporins. ELI LILLY & CO. 10 March, 1970 [10 March, 1969], No. 11343/70. Heading C2A. 3 - Methyl - 7 - amino - cephalosporins of formula wherein R<SP>1</SP> is hydrogen or an easily removable carboxyl-protecting group, are prepared by treating a corresponding 3-methyl-7-acylamino cephalosporin with at least 1 molar proportion of a solvent of formula R<SP>11</SP>-OH at 0-125 C. in the presence of at least 0À25 equivalent of an acid having a pKa below 3, R<SP>11</SP> being hydrogen, methyl, ethyl or propyl and the acylating group in the starting cephalosporin having the formula or in which Q is hydrogen, C 1 -C 3  alkyl, C 1 -C 3  alkoxy, cyano, nitro, hydroxy, chloro, bromo or fluoro; Y is hydrogen or hydroxy; X is oxygen or sulphur; m is 0, 1 or 2; and n is 1, 2 or 3. The carboxyl-protecting group may be an easily removable esterifying group; preferred starting materials are those wherein the acylating group is benzyl or phenoxymethyl. When the solvent R<SP>11</SP>-OH is water, an inert watermiscible organic co-solvent is preferably added to maintain the reactants and products in solution. Suitable acids are p-toluenesulphonic acid, methanesulphonic acid, trifluoroacetic acid, hydrochloric acid, phosphoric acid and sulphuric acid. The product may be obtained in the form of the salt of the acid used, e.g. pnitrobenzyl - 3 - methyl - 7 - amino - A<SP>3</SP> - cephem- 4 - carboxylate p - toluenesulphonic acid salt monohydrate.
Patent GB-1266262-A (GB)
IPC: G01L3/24
Filed: 1970-03-20
Abstract: 1,266,262. Aircraft instruments. BENDIX CORP. 20 March, 1970 [26 March, 1969], No. 13555/70. Heading B7W. [Also in Division G1] An arrangement for determining the reserve capability of a turbine engine-for example a turbine engine in a helicopter-comprises a power margin computer receiving signals indicative of static pressure, ambient temperature and engine torque and providing a signal indicative of the percentage of maximum rated torque being produced by the engine. As described the arrangement is applied to engines in a helicopter to enable the pilot to determine whether his cargo load and mission destination are within the capabilities of the engines. As shown in Fig. 3 sensors are provided to sense engine torque 4, 5, fuel weight 6, temperature 7, pressure 76, air frame weight 77 and collective pitch 78, these being fed into the power margin computer 1. Provision is also made for signals to be fed into the computer from a destination control panel 18 these signals corresponding to destination temperature, destination fuel reserve required, and humidity. Interrogation signals may also be fed into the computer for destination maximum cargo and destination power. The computer provides output signals to an indicator 2 to indicate cargo weight 10, and percentage of maximum torque for each engine. A STOL index 9 is provided to indicate when a STOL type landing may be necessary. Means 11 provide signals to the computer for adjusting for sub-normal engine operation and a switch 12 initiates a signal for the computer to provide signals indicating actual torque. The computer also provides signals to an indicator 3 to show airspeed, maximum range, and best speed for maximum range or endurance. A cargo update control is provided. The Specification disclosed in block diagram form the circuit arrangement of the computer (Figures not shown). Fig. 5 (not shown) discloses that the measures of rated torque and density ratio are derived from potentiometers whose movable contacts are connected to a diaphragm which moves under variable pressure conditions.