baber/WOPTO huggingface dataset:
Patent CA-2913052-A1 (CA)
Inventor: COOPER LAURENCE J
IPC: C12N5/07
Filed: 2014-05-23
Abstract: Provided are monoclonal antibodies that detect CD 19 CAR-modified immune cells and CAR-modified immune cells irrespective of the tumor associated antigen they target. Methods of using these functional monoclonal antibodies include, but are not limited to, detection, quantification, activation, and selective propagation of CAR-modified immune cells.
Patent CA-2915033-A1 (CA)
Title: Procedes, necessaires et systemes pour detection multiplexe de molecules cibles et leurs utilisations
Inventor: WEISSLEDER RALPH
IPC: C12P19/34
Filed: 2014-06-03
Abstract: La présente invention concerne des procédés, des compositions, des nécessaires et des systèmes pour détection multiplexe de molécules cibles dans un échantillon. Selon certains modes de réalisation, lesdits procédés, compositions, nécessaires et systèmes peuvent être utilisés pour mettre en uvre une analyse multiplexe des protéines d'un échantillon (par exemple, d'un échantillon contenant un petit nombre de cellules ou une seule cellule). Selon certains modes de réalisation, l'échantillon soumis à une analyse multiplexe des protéines utilisant les procédés, compositions, nécessaires et systèmes de l'invention peut également être soumis à une analyse des acides nucléiques (par exemple ARN, microARN et/ou ADN), ce qui permet un profilage intégré de l'expression à partir d'une quantité limitée d'échantillon.
Patent CA-2920679-A1 (CA)
Inventor: MUMM JOHN BRIAN
IPC: A61K47/48
Filed: 2014-08-26
Abstract: Methods of treating subjects having diseases, disorders, or conditions, including disorders associated with cholesterol homeostasis, responsive to IL-10, including methods of administration and dosing regimens associated therewith, are provided, More particularly, the present disclosure relates to optimized dosing parameters to achieve and maintain efficacy in the treatment and/or prevention of metabolic diseases, disorders and conditions in a subject, while minimizing the adverse effects associated therewith. Particular embodiments are directed to the treatment and/or prevention of abnormally high levels of cholesterol and/or manifestation(s) of hypercholesterolemia in as subject.
Patent CA-2922883-A1 (CA)
Inventor: BRAUNER BILL E
IPC: F21V33/00
Filed: 2014-08-27
Abstract: A lighted hand tool includes a cylindrical-shaped rivet member, and a first and second tool member each having a handle, a jaw, and a pivot portion therebetween. A cylindrical bore section is defined by each pivot portion, and each bore is in co-axial alignment for aligned receipt of the rivet member therein. The rivet member prevents lateral separation of the first and second hand tool therebetween, while enabling pivotal movement of the jaw portions. An illumination device is formed for sliding receipt in the receiving channel of the rivet member, and aligns an output portion with the communication port to illuminate the work area. A first end cap and second cap are threadably disposed in the opposite openings into the rivet member. The first and second end cap cooperate to securely abut and seat the illumination device therebetween.
Patent CA-2923392-A1 (CA)
Inventor: BIFFI ANDREA
IPC: A61P1/00
Filed: 2014-09-05
Abstract: The present invention relates to the use of a composition comprising bacteria to increase the intestinal production of butyric acid, folic acid or niacin and/or to decrease the intestinal production of succinic acid. Moreover, the present invention relates to the use of said composition for the treatment and/or prevention of an intestinal butyrate- and/or succinate- dependent pathological condition. In particular, for the treatment and/or the prevention of intestinal inflammation, diarrhoea, ulcerative colitis or intestinal colopathies.
Patent CA-2926717-A1 (CA)
Inventor: HOPKINSON EMMA K
IPC: G06Q20/34
Filed: 2014-10-07
Abstract: Systems, methods, and computer program products are provided for managing contactless transactions. A tap notification including at least a first identifier is received. A first counter in a first data set associated with the first identifier is incremented. It is determined if the first counter matches one of a plurality of thresholds. If it is determined that the first counter matches one of a plurality of thresholds, a first status level in the first data set is updated. A first set of benefits from a plurality of benefits stored in a memory based on the first status level is identified. The first set of benefits is associated with the first identifier.
Patent CA-2927701-A1 (CA)
Inventor: HOBBS ERIC D
IPC: C12M1/34
Filed: 2014-10-22
Abstract: A microfluidic device can comprise at least one swept region that is fluidically connected to unswept regions. The fluidic connections between the swept region and the unswept regions can enable diffusion but substantially no flow of media between the swept region and the unswept regions. The capability of biological micro-objects to produce an analyte of interest can be assayed in such a microfluidic device. Biological micro-objects in sample material loaded into a microfluidic device can be selected for particular characteristics and disposed into unswept regions. The sample material can then be flowed out of the swept region and an assay material flowed into the swept region. Flows of medium in the swept region do not substantially affect the biological micro-objects in the unswept regions, but any analyte of interest produced by a biological microobject can diffuse from an unswept region into the swept region, where the analyte can react with the assay material to produce a localized detectable reaction. Any such detected reactions can be analyzed to determine which, if any, of the biological micro-objects are producers of the analyte of interest.
Patent CA-2930272-A1 (CA)
Inventor: SMITH COLIN
IPC: E21B34/14
Filed: 2011-03-10
Abstract: A mechanical counting device is locatable within a tool and comprises a tubular body having a bore. A first set of dogs are carried by the tubular body and are radially moveable relative to the bore of the tubular body between radially extended and retracted positions. A second set of dogs are carried by the tubular body and are radially moveable relative to the bore of the tubular body between radially extended and retracted positions. The tubular body is configured to be linearly progressed along an associated tool in response to receiving an object transported at least partially through the tubular body and sequentially engaging the first and second sets of dogs.
Patent CA-2931038-A1 (CA)
Title: Cleaning tool
Inventor: MCMANN LARRY R JR
IPC: A47L13/16
Filed: 2014-11-20
Abstract: A cleaning tool comprising a handle assembly and a pad assembly. The pad assembly is coupled to the handle assembly such that the handle assembly extends distally beyond a first end of the pad assembly. The pad assembly includes a pad securing surface having a plurality of pad securing members extending substantially perpendicularly from the pad securing surface, and a slotted member located at a second end of the pad assembly, the second end being opposite the first end. The slotted member defines a slot configured to accept a cleaning pad, and the slotted member extends at an angle from the pad securing surface.
Patent CA-2934347-A1 (CA)
Inventor: HANSEN LARS
IPC: F28D7/14
Filed: 2014-12-18
Abstract: Tubing (1) and a method for heat exchange between a first fluid which is in the tubing (1) and a second fluid which is outside the tubing (1), the tubing (1) extending between a first end portion (3) and a second end portion (5), the tubing (1) comprising an inner tube (1') and an outer tube (1") which is arranged on the outside of the inner tube (1'), the inner tube (1') being connected to the outer tube (1") in a fluid-tight manner at the first end portion (3), the first end portion (3) being surrounded by and attached to a fluid-supply pipe (7), and there being, in the second end portion (5), a passage between the inner tube (1') and the outer tube (1").
Patent CA-2935830-A1 (CA)
Inventor: IDUPUNUR KRISHNA
IPC: G08G5/00
Filed: 2016-07-11
Abstract: The embodiments described herein can provide systems and methods for combining traditional navigational data with temporary updates. Such a system and method can facilitate the inclusion of temporary navigational events into the navigational data made available on aircraft flight management system (FMS). For example, the systems and methods can be used to combine Aeronautical Information Regulation and Control (AIRAC) navigational data that is traditionally updated on 28 day cycles, with temporary navigational data changes, such as those typically indicated in "Notices to Airmen" (NOTAM). The combined navigational dataset can then be provided to the FMS.
Patent CA-2936633-A1 (CA)
Inventor: PESYNA KENNETH M
IPC: B64D33/10
Filed: 2016-07-20
Abstract: A propulsion system including a gas turbine engine is disclosed herein. The propulsion system further includes a heat exchanger arranged outside the gas turbine engine and adapted to cool fluid from the gas turbine engine.
Patent CA-2937017-A1 (CA)
Title: Application integree de conception
Inventor: TUNG TERESA
IPC: G06Q30/00
Filed: 2009-10-02
Abstract: Des modes de réalisation de linvention portent sur un processus et un système pour concevoir des systèmes dapplication composites. Un mode de réalisation de linvention est un processus de conception dun système dapplication composite pour répondre à une exigence dapplication. Le processus consiste à définir un scénario dutilisation exécuté par un système dapplication composite pour répondre à lexigence dapplication, à intégrer le scénario avec un outil dexécution et à spécifier une infrastructure sous-jacente pour la conception du système, tout le processus étant exécuté dans une application logicielle intégrée.
Patent CA-2937635-A1 (CA)
Inventor: JURETICH JEFFERY T
IPC: A61M5/168
Filed: 2015-01-14
Abstract: An infusion pump (10) has an optical detection system (50) for determining whether or not a cassette (14) of an administration tubing set is properly loaded in the pump. Operation of the pump may be enabled or disabled based on a determination of the optical detection system. The optical cassette detection system includes a light emitter (52) and a corresponding light detector (54) on non- coincident emission and detection axes, and at least one optical element (55) carried by the cassette. When the cassette is properly loaded in the pump, light from the emitter is redirected by the optical element from the emission axis to the detection axis for receipt by the detector, which registers an increased signal level. The detector signal is evaluated by signal evaluation electronics to determine if the detector signal level is above a predetermined threshold, indicating presence of the cassette.
Patent CA-2938018-A1 (CA)
Inventor: TSUKADA SHINGO
IPC: A61B5/0408
Filed: 2015-01-27
Abstract: Provided are an electrode member and a device capable of maintaining high electrical conductivity even after repeated washing, and of also being applied as an electrode for an organism. This electrode member is characterized by being a fiber structure configured from a textile or the like including an electroconductive polymer, wherein an electroconductive polymer such as a polythiophene-based electroconductive polymer is supported on the surfaces of single fibers and/or in spaces between single fibers constituting a multifilament used in the fiber structure.
Patent CA-2940173-A1 (CA)
Title: Thermal defogging system and method
Inventor: MAKMEL NIR
IPC: H05B3/84
Filed: 2015-02-20
Abstract: A thermal defogging system and method for an optical instrument is described. In one embodiment, the thermal defogging system for an optical instrument is comprised of: at least a primary housing, the primary housing defining an aperture for transmission of optical signals, a transparent element adapted to be aligned with the aperture for transmission of optical signals, at least one side of the transparent element facing the external environment; and a transparent conductive layer covering an area at least as large as the optical footprint of the transmitted optical signal through the transparent element, wherein responsive to the application of electrical power to the transparent conductive layer, the transparent conductive layer generates heat that is thermally communicated to the least one side of the transparent element facing the external environment.
Patent CA-2940845-A1 (CA)
Title: Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases
Inventor: WYNN THOMAS ANDREW
IPC: A61K31/18
Filed: 2015-02-24
Abstract: The present invention provides compounds of Formula (I) and pharmaceutical compositions for treating neurological diseases such as multiple sclerosis. (see formula I)
Patent CA-2942753-A1 (CA)
Title: Substituted fused heterocycles as gpr119 modulators for the treatment of diabetes, obesity, dyslipidemia and related disorders
Inventor: SCHWINK LOTHAR
IPC: A61P3/00
Filed: 2015-04-02
Abstract: The present invention relates to substituted fused heterocyclic compounds. The substituted fused heterocyclic compounds are GPR1 19 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the use of substituted fused heterocyclic compounds as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.
Patent CA-2944641-A1 (CA)
Inventor: SADLER ROBERT LEE
IPC: H04N21/472
Filed: 2016-10-05
Abstract: The various embodiments of the present disclosure are directed to devices, systems and methods for providing media content. Per one embodiment, a method includes receiving bookmarking data at a client device from a data processing and aggregating server, the bookmarking data referencing a specific point in a media content item that is playable from the client device; providing a first output signal based on the bookmarking data from the client device to a display device, the output signal causing the display device to display at least one bookmark that includes at least a user-selectable portion and a descriptive portion; receiving an input signal at the client device from a user input device, the input signal indicating a user selection of a bookmark displayed by the display device; and providing a second output signal from the client device to the display device responsive to the input signal, the second output signal causing the display device to display a media content item from a specific point specified by the bookmarking data.
Patent CA-2945692-A1 (CA)
Title: Traitements pour l'acne resistante
Inventor: SENGUPTA SHILADITYA
IPC: A61P31/04
Filed: 2015-01-29
Abstract: La présente invention concerne d'une manière générale de nouvelles molécules, compositions, et formulations pour le traitement d'infections bactériennes en général et plus spécifiquement des infections bactériennes avec des agents pathogènes résistants aux antibiotiques.
Patent CA-2946642-A1 (CA)
Inventor: Reese Lloyd Wayne
IPC: B61B3/00
Filed: 2016-10-27
Abstract: A zip line includes a substantially rigid track supported above a ground surface by a plurality of supports, a trolley which moves along the track, and a rider support suspended from the trolley. The track is comprised of a plurality of track segments connected together such that adjacent track segments have substantially no freedom of movement relative to each other, and such that adjacent track segments present a substantially smooth, continuous, and uninterrupted surface. The track includes a run and a flange extending upwardly from the run. The trolley comprises a frame having upper wheel mounts to which first and second upper wheels are rotatably mounted. The first upper wheels are oriented such that they engage an upper surface of the track run and the second upper wheels are oriented such that they will engage the track flange upon rotational movement of the trolley relative the track run.
Patent CA-2947820-A1 (CA)
Inventor: HOLSTEN HENRY E
IPC: A61B17/94
Filed: 2016-11-08
Abstract: The present disclosure relates to endoscopic reposable surgical clip appliers having a reusable handle assembly, at least one reusable shaft assembly, and at least one disposable clip cartridge assembly.
Patent CA-2948204-A1 (CA)
Inventor: KOWAL JENS
IPC: A61B3/15
Filed: 2015-04-30
Abstract: In a method for the acquisition of optical coherence tomography image data of retina tissue of an eye (99) of a human subject using an acquisition device comprising an imaging optics (2), a first image associated with a baseline relative positioning of the eye (99) of the human subject with respect to the imaging optics (2) is acquired at a first point in time. The baseline relative positioning is stored. At a second point in time being different from the first point in time, the baseline relative positioning of the same eye (99) of the same human subject with respect to the imaging optics (2) is re-established and a second image is acquired. For re-establishing the positioning, a present relative positioning of the eye (99) of the human subject with respect to the imaging optics is determined based on a video image of an iris region of the eye. A corresponding device comprises an imaging optics (2), a head support to be contacted by a head portion of the human subject, the head support defining an entrance position of the sample beam entering an eye of the human subject, a camera (71 ) for acquiring a video image of an iris region of the eye, a display (75) for displaying a target image to the human subject, the target image indicating a direction of a line of vision to be assumed by the human subject, and a processor for determining a present relative positioning of the eye of the human subject with respect to the imaging optics, based on the video image, for comparing a present relative positioning of the eye (99) of the human subject with respect to the imaging optics (2) to a stored baseline relative positioning, for affecting the target image as long as the present relative positioning does not correspond to the stored baseline relative positioning, and for triggering the acquisition of image data when the present relative positioning corresponds to the baseline relative positioning.
Patent CA-2951883-A1 (CA)
Title: N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide hydrochloride salts
Inventor: BROWN BRANDON H
IPC: C07D239/42
Filed: 2015-06-11
Abstract: The present invention relates to stable novel salt forms of N-(cyanomethyl)-4-(2-(4- morpholinophenylamino)pyrimidin-4-yl)benzamide that are suitable for the preparation of pharmaceutical formulations thereof, and their therapeutic use.
Patent CA-2954783-A1 (CA)
Inventor: VON FELLENBERG SVEN
IPC: F03B3/02
Filed: 2015-04-30
Abstract: A Francis turbine runner including a shortened band length and a shortened blade length combined with a reversed runner blade leading edge having a junction of the leading edge with the band forerunning a junction of the leading edge with the crown in the rotational direction, and a bandless runner including a shortened periphery length and a shortened blade length combined with a reversed runner blade leading edge having a corner of the leading edge at the outer periphery of the runner that is in advance of where the leading edge joins the crown in the rotational direction. Additional feature includes an inverted trailing edge curvature design on the runner blade that further shortens the blade length.
Patent CA-2955776-A1 (CA)
Inventor: MCVEEN KEITH MICHAEL
IPC: A63G31/16
Filed: 2015-07-07
Abstract: A vehicle transportation room system and method are disclosed. In one embodiment, a system may include a ride vehicle (14) disposed on a ride path (22, 42) and a launch room vehicle (10) may be configured to align with the ride vehicle on the ride path and include an at least partial room (12). The launch room vehicle may be configured to house the ride vehicle in the at least partial room and to move with the ride vehicle and then break coordination with the ride vehicle such that the ride vehicle launches from the at least partial room. Further, the launch room vehicle may include a show element (106) that is operated as the at least partial room moves with the ride vehicle to simulate that the show element is interacting with the ride vehicle.
Patent CA-2956114-A1 (CA)
Title: Systeme de pile a combustible
Inventor: KANEKO YOUHEI
IPC: H01M8/04
Filed: 2014-07-24
Abstract: La présente invention concerne un système de pile à combustible pourvu d'un compresseur pour fournir un gaz de cathode à des piles à combustible, et d'un dispositif d'entraînement qui, pour entraîner le compresseur, est pourvu d'un total d'au moins deux moteurs d'entraînement et/ou corps d'entraînement ayant une source d'énergie autre qu'un moteur d'entraînement, la source d'énergie du système de pile à combustible étant utilisée comme source d'énergie des corps d'entraînement.
Patent CA-2956699-A1 (CA)
Title: Optical isomer of 1,4-benzothiazepine-1-oxide derivative, and pharmaceutical composition prepared using same
Inventor: KANEKO NOBORU
IPC: C07D417/06
Filed: 2015-07-17
Abstract: The present invention provides: a novel compound which is characterized by being capable of increasing the number of heart beats or a blood pressure mildly to improve hemodynamics, and which is useful as a therapeutic or prophylactic agent for atrial fibrillation and heart failure; and a pharmaceutical composition which contains the compound. The present invention relates to: an optical isomer of a 1,4-benzothiazepine-1-oxide derivative represented by general formula [II] (wherein R represents a hydrogen atom or a hydroxy group; and * indicates the presence of an optical isomer) or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition which contains the optical isomer or a pharmaceutically acceptable salt thereof.
Patent CA-2957506-A1 (CA)
Title: Information-processing system
Inventor: DOMOTO RYO
IPC: G06Q30/02
Filed: 2015-08-07
Abstract: This information-processing system is provided with a storage unit (55) and a combining unit (51). The combining unit is configured so as to combine a first and a second database (155) stored by the storage unit. The first database is provided with feature data on imagined constituent bodies on the basis of feature data on constituent bodies of a first group, the feature data being composed of an integrated plurality of feature data on constituent bodies in which the features are the same or different. The second database is provided with feature data on constituent bodies in a second group. Each of the elements of feature data provided in the first and the second database contain reference data representing shared types of features. The combining unit combines the first database and the second database so as to combine the feature data, which has features that are the same or different, that the reference data represents between the first database and the second database.
Patent CA-2960453-A1 (CA)
Inventor: UMANA PABLO
IPC: G01N33/68
Filed: 2015-10-22
Abstract: Herein is reported an anti-drug antibody immunoassay for the determination of the presence of an anti-drug antibody against an effector function suppressed human or humanized drug antibody in a sample comprising the incubation of a sample comprising mammalian blood serum with full length human Fcgamma receptor I or an Fc-region binding fragment thereof so that a complex between the anti-drug antibody against the effector function suppressed human or humanized drug antibody present in the sample and the human Fcgamma receptor I or the Fc-region binding fragment thereof forms, whereby the full length human Fcgamma receptor I or the Fc-region binding fragment thereof is conjugated to a detectable label, and the determination of the formed complex by the detectable label.