baber/WOPTO huggingface dataset:
Patent IE-35658-L (IE)
Title: Producing 7 - aminocephalosporanic acid
IPC: C07D/
Filed: 1971-09-22
Abstract: 1354017 Preparing 7-aminocephalosporanic acids TOYAMA CHEMICAL CO Ltd 5 Oct 1971 [17 Oct 1970] 46274/71 Heading C2A 7-Aminocephalosporanic acids are prepared by protecting the 4-carboxyl group of a 7- acylaminocephalosporanic acid by converting it to a mixed acid anhydride, reacting the anhydride with an imido halide-forming reagent to form the corresponding imido halide, reacting the latter with a hydroxyl compound RÀOH where R is an optionally substituted alkyl, aryl, aralkyl, alicyclic or alicyclic-alkyl group, and then hydrolyzing the resulting imino ether to give the desired product. The starting cephalosporin, preferably as its amine, alkali metal or alkaline earth metal salt, is converted to the mixed acid anhydride by reaction with a compound of formula wherein each of R<SP>1</SP> and R<SP>2</SP>, which may be the same or different, is halogen, an alkyl, aryl, aralkyl, alkoxy, aryloxy or aralkyloxy group which groups may be substituted, or R<SP>1</SP>, R<SP>2</SP> and M<SP>1</SP> may together form a ring, M<SP>1</SP> is boron, aluminium or phosphorus and X is a halogen atom; R<SP>3</SP>, R<SP>4</SP> and R<SP>5</SP> are each substituted or unsubstituted alkyl, aryl, aralkyl, alkoxy, aryloxy or aralkyloxy group, or each of R<SP>4</SP> and R<SP>5</SP> may be a halogen atom, or R<SP>4</SP> and R<SP>5</SP> taken together represent O, S or O 2 , or R<SP>4</SP>, R<SP>5</SP> and M<SP>2</SP> may together form a ring, M<SP>2</SP> is a carbon or sulphur atom and X is halogen; and each of R<SP>9</SP>, R<SP>10</SP>, R<SP>11</SP> and R<SP>12</SP> is a halogen atom or an alkyl, aryl, aralkyl, alkoxy, aryloxy or aralkyloxy group which groups may be substituted, or R<SP>9</SP> and R<SP>10</SP> taken together represent O, or R<SP>11</SP>, R<SP>12</SP> and M<SP>4</SP> may together form a ring, M<SP>4</SP> is a phosphorus atom and X is halogen. The reaction is preferably effected in an insert solvent in the presence of an acid-binding agent. The resulting solution of mixed acid anhydride is then treated with the imide halide-forming reagent, e.g. POCl 2 , PCl 5 , PBr 3 , PBr 5 , COCl 2 , SOCl 2 , oxalyl chloride, protocatechinylphosphorus trichloride or toluenesulphonyl chloride. The imide halide produced is then converted to the corresponding imino ether by reaction with the aforesaid hydroxyl compound R.OH (e.g. methyl, ethyl, propyl, butyl, amyl or benzyl alcohol, ethylene glycol, ethylene chlorohydrin, #-cyanoethanol, 2-ethylhexanol, cyclohexanol, or ethyleneglycol monomethyl or monoethyl ether). The imino ether is subsequently hydrolyzed by treatment with ice water, which effects simultaneous hydrolysis of the imino ether moiety to -NH 2 and of the mixed acid anhydride group to -COOH, resulting in the desired 7-aminocephalosporanic acid. The latter may be isolated from the hydrolysis mixture by addition of a basic substance to bring the pH to the isoelectric point of the product so that it crystallizes out from the solution.
[GB1354017A]
Patent IE-881247-L (IE)
Title: Reduction of esters
IPC: C07C41/01
Filed: 1988-04-26
Abstract: A method for producing a compound of the formula: [wherein R<1> and R<2> each stand for a lower alkyl group; n denotes an integer of 0 to 21; X stands for hydrogen atom or an optionally protected hydroxyl group; and Y stands for an optionally protected hydroxyl group], which comprises by reducing an ester compound of the formula: [wherein R<1>, R<2>, n, X and Y are of the same meaning as defined above, and R<3> stands for a lower alkyl group] with a mixture of sodium borohydride and aluminum chloride, gives the desired compound in a high yield, and is advantageous from the industrial point of view.
Patent IE-36966-L (IE)
Title: Sliding clasp fastener stringer
IPC: A44B19/02
Filed: 1972-10-11
Abstract: A slide-fastener stringer has its turns (of continuous coil or meander coupling element) secured to its fabric support tapes by means of single-needle or double-needle double chain-stitch or lockstitch wherein bights of the needle thread straddle the coil turns and pass through the filler cords. The U-shaped bights of the needle-thread loops of each stringer half snugly embrace the individual turns and this thread is so tensioned that the looper or gripper thread lies completely along the opposite face of the support tape. The support tape is formed parallel to at least one of its longitudinal edges with a longitudinally extending valley or channel in which the looper, locking or gripper thread lies. In addition the upper side of the coil is formed with a longitudinally extending groove (formed by notches in the shanks of the turns) in which the needle thread lies. After stitching of the interleaved coils to the tapes the thermoplastic monofilament needle thread which has been stretched, is heated to thermally fix and shrink it.
[US3783476A]
Patent IE-891376-L (IE)
Title: Lignocellulose degradation
IPC: C07D307/48
Filed: 1989-04-26
Abstract: A process for producing furfural and levulinic acid from lignocellulose includes subjecting a sample of lignocellulose to acid degradation at an elevated temperature for a minute or less, during which time at least fifty percent of the furfural that theoretically can be derived from the sample is generated. The resulting mixture is then subjected to a second acid degradation at an elevated temperature to produce levulinic acid. During the second acid degradation, furfural vapors are continuously collected from the mixture.
[US4897497A]
Patent IE-871424-L (IE)
Title: Well bore fluid
IPC: C09K8/82
Filed: 1987-05-29
Abstract: A method for the completion or work-over of a well comprises the step of using a solids-free, non-aqueous well-bore fluid comprising a halogenated organic compound as a completion or work-over fluid. The fluid has a specific gravity in the range 0.9 to 2.3. Preferred halogenated organic compounds are brominated aromatic ethers, diphenyls, aliphatic hydrocarbons, benzene and alkyl benzenes. The halogenated organic compound may be dissolved in an organic solvent. The relative proportions may be chosen to provide a well-bore fluid having a desired specific gravity. The fluids are non-corrosive, thermally stable and non-damaging to formations.
[EP0247801A2]
Patent IE-851478-L (IE)
Title: Dialkoxypyridines
IPC: C07D235/26
Filed: 1985-06-14
Abstract: Dialkoxypyridines of formula I <IMAGE> (I) wherein R1 is 1-3C-alkyl which is completely or predominantly substituted by fluorine, or a chlorodifluoromethyl radical and R1' is hydrogen, halo, trifluoromethyl, 1-3C-alkyl, or 1-3C-alkoxy which is optionally completely or predominantly substituted by fluorine, or R1 and R1', together with the oxygen atom to which R1 is bonded, are 1-2C-alkylenedioxy, which is optionally completely or partly substituted by fluorine, or chlorotrifluoroethylenedioxy, R3 is 1-3C-alkoxy, one of R2 and R4 is 1-3C-alkoxy and the other is a hydrogen atom or 1-3C-alkyl and n is 0 or 1, and salts thereof are new compounds with a pronounced protective action on the stomach. Processes for preparing these compounds, medicaments containing them and their use, as well as intermediate compounds and their use for preparing the subject dialkoxypyridines, are disclosed.
[US4758579A]
Patent IE-33654-L (IE)
Title: Separation of liquids from solids
IPC: C02F1/52
Filed: 1969-11-21
Abstract: 1,267,106. Settling of finely divided solids materials from suspension in liquids. AMERICAN SUGAR CO. 20 Nov., 1969 [26 Nov., 1968], No. 56910/69. Heading B1D. [Also in Divisions C1 and C6] Finely divided solid materials are separated from suspension in a liquid, such as a carbonation juice from a beet or cane sugar factory, by adding a small proportion (e.g. 0.1 to 30 ppm) of a settling aid, such as polyacrylamide having a molecular weight of 2 to 3 millions, whereby a slurry of solid agglomerates in liquid is obtained, introducing the slurry through a central standpipe 34 into a central position 32 above the bottom of a settling vessel, arresting the upward motion of the influent slurry and displacing it outwards by means of horizontal baffle 40 so that it is dispersed with the liquid in the settling zone 44 from which large agglomerates of solids rapidly settle, removing dense slurry of solids from well 36 through outlet 50, and removing clarified liquid from a peripheral opening 52 at the top of the settling vessel. The clarified liquid is collected in trough 54, and withdrawn through outlet 56. The height of baffle 40 can be adjusted to facilitate variation in the level at which the slurry is introduced into the settling vessel. The depth of the settling zone 44 is partly controlled by rakes 68, attached to rotary disc 72, which move the agglomerates into well 36. The upper boundary of the settling zone may be maintained at level 66 by a pump attached to outlet 50, the pump being controlled by a photo-electric cell 84 sensitized by light from lamp 86 transmitted through clear plastic rod 88. The settling process and apparatus may also be employed in water softening by the lime-soda process.
[GB1267106A]
Patent IE-781733-L (IE)
Title: Seizing device for load handling
IPC: B66C1/00
Filed: 1978-08-28
Abstract: A device for seizing and handling a load which has a given inclination includes a frame which is adapted to be suspended at a point of the frame from a handling machine. The frame is adapted to be locked to the load. A device is provided for shifting the suspension point in a reference direction relative to the frame. A level detector is mounted on the frame to pivot in a vertical plane parallel to the reference direction and produces a signal when it deviates from a horizontal position. The device for shifting the suspension point is responsive to the signal and shifts the suspension point, upon the hoisting of the load, to a position in which the load cancels out the deviation from horizontality of the level detector. Regulating apparatus regulate the relative angular position of the detector relative to the frame in the vertical plane so as to bring the detector to a horizontal position in which it stores the given inclination of the load. A control device responsive to the signal of the detector controls the regulating apparatus in such manner as to automatically pivot the detector to the horizontal position prior to the hoisting of the load. A device inhibits the control device so as to maintain, in the course of the hoisting of the load, the level detector in the relative position in which it stores the given inclination of the load.
[US4245941A]
Patent IE-811825-L (IE)
Title: Automatic test system
IPC: G01D21/00
Filed: 1981-08-10
Abstract: An automatic test system controlled by a general purpose digital central processor is disclosed. The central processor accepts test programs in a high level compiler language such as Atlas. The Atlas program is compacted into a simplified language which is utilized to communicate with test devices via a standard IEEE 488 data bus. Each of the test devices includes a programmable interface digital processor which performs any translation that may be necessary in order to permit specific test instruments coupled to the central processor via the interface processor to perform the tests specified by the high level test programs. A switching matrix also communicates with the digital processor to connect the appropriate test device to the unit under test.
[US4402055A]
Patent IE-41604-L (IE)
Title: Device for the inhalation of medicament
IPC: A61M13/00
Filed: 1975-08-22
Abstract: Apparatus for the inhalation of medicinal agent is disclosed which comprises forming an aerosol, containing the medicinal agent, within a venturi tube-shaped interior configuration. The apparatus comprises a housing for receiving incoming air and combining the same with a medicinal agent passed from a container supported on the housing. The housing has a converging air inlet chamber in communication with an adjacent constriction. The constriction, in turn, communicates with an aerosol delivery section via a diverging diffuser chamber. The diffuser chamber may be part of the housing and the delivery section, which section provides for oral or nasal application may be attached thereto. In the alternative, the diffuser chamber and aerosol delivery section may comprise a single section integrally formed with the housing. The diffuser chamber, constriction and air inlet chamber cooperate to define the venturi tube-shaped configuration. Medicinal agent from the container enters the housing interior proximate the constriction, thoroughly combines with incoming air to form an aerosol, and exhausts through the aerosol delivery section.
[US4046146A]
Patent IE-792074-L (IE)
Title: Pyran- and thiopyran-fused heterocyclic compounds
IPC: A61P37/08
Filed: 1979-10-30
Abstract: There are described compounds of formula I, <IMAGE> I in which an adjacent pair of R5, R6, R7 and R8 form a chain -CZC(G1)=(G2)-Z-, R4, R9 and the remainder of R5, R6, R7 and R8, which may be the same or different, each represent hydrogen, alkyl, halogen, alkenyl, -NO2, -NR1R2, -OR3, -S(O)nR3; or alkyl substituted by hydroxy, amino, alkoxy or carbonyl oxygen, n is 0, 1 or 2, R1 and R2, which may be the same or different, each represent hydrogen, alkyl, -CONHR3, phenyl or phenyl substituted by alkyl or halogen, or R1 and R2 together with the nitrogen atom to which they are attached form a 5 or 6 membered heterocyclic ring, R3 represents hydrogen, alkyl, alkenyl or phenyl, one of G1 and G2 is hydrogen and the other is a group E, each E, which may be the same or different, is -COOH, a 5-tetrazolyl group, or a carboxamidotetrazole group, each Z, which may be the same or different, is oxygen or sulphur, and one or two of the atoms, a, b, c and d are nitrogen atoms and the remainder are carbon atoms, R9 having no significance when two of a, b, c and d are nitrogen, (with certain exclusions) and pharmaceutically acceptable derivatives thereof. There are also described methods for making the compounds and pharmaceutical, e.g. anti-allergic, compositions and mixtures containing them.
[US4419352A]
Patent IE-872165-L (IE)
Title: Quinoxaline derivatives
IPC: C07D241/44
Filed: 1987-08-13
Abstract: Heterocyclic dihydroxyquinoxaline compounds having the formula <CHEM>  wherein    R<1> is halogen, CN, CF3, ethynyl, or N3  and    R<2> is SO2C1-3-alkyl, CF3, NO2, ethynyl, or CN. The invention also relates to a method of preparing the compounds, pharmaceutical compositions thereof, and their use. The compounds are useful in the treatment of indications caused by hyperactivity of the excitatory neurotransmitters, particularly the quisqualate receptors, and especially as neuroleptics.
Patent IE-882341-L (IE)
Title: Vapor sterilization of medical instruments
IPC: A61L2/20
Filed: 1988-07-29
Abstract: A method and device for enhancing the vapor sterilization of the lumen of medical instruments and like articles under reduced pressure. A vessel (14) containing a small amount of a vaporizable liquid sterilant solution is attached to the lumen. The sterilant vaporizes and flows directly into the lumen of the article as the pressure is reduced for the sterilization cycle.
[EP0302419A2]
Patent IE-782451-L (IE)
Title: Flexible tubular container
IPC: B65B51/08
Filed: 1978-12-12
Abstract: A flexible tubular container having at least one end gathered and bound by filamentary material (4) which is held in position by adhesive material. The container is advantageously made from a continuous length of flexible tube by gathering and constricting the tube (1) at spaced apart positions, winding filamentary binding material along a portion of the constricted tube, applying adhesive material to the binding material to fix the binding material in position and cutting the bound portion of the tube transversely (7) whereby a container sealed at each end is defined and separated from the adjacent portions of the flexible tube. The preferred adhesive is cyanoacrylate adhesive or hot-melt adhesive.
[EP0003256A1]
Patent IE-892459-L (IE)
Title: NEW USE OF 5-HETEROARYL- OR 5-ARYL-SUBSTITUTED IMIDAZO¹£2,1-a|ISOQUINOLINES
IPC: C07F7/08
Filed: 1989-07-28
Abstract: The invention discloses certain 5-hetero or aryl-substituted-imidazo[2,1-a]isoquinolines useful as platelet activating factor (PAF) receptor antagonists, pharmaceutical compositions containing said compounds as an active ingredient thereof and a method of using such compositions for inhibiting PAF-mediated bronchoconstriction and extravassation and PAF-mediated, endotoxin-induced lung injury, and for controlling hyperreactive airways induced by PAF or allergin. In addition, the invention discloses the use of a select group of said compounds as anti-tumor agents.
[US4910206A]
Patent IE-862512-L (IE)
Title: Arylmethylazoles
IPC: C07D521/00
Filed: 1986-09-22
Abstract: Arylmethylazoles of the formula I <IMAGE> I in which Aryl is (substituted) phenyl or naphthyl; Z is CH or N; R1 and Q are H or alkyl; R2 is H, alk(en)yl or alkynyl; R3 and R4 are H, alkyl or other hydrocarbons; or R3 and R4 together are a -(CH2)2-11 chain or a bridged -(CH2)4-5 chain, and their acid addition salts, stereoisomers and optically active enantiomers possess outstanding antimycotic and antidepressant activity. They are obtained, inter alia, from arylmethylazoles II <IMAGE> II which are reacted with a strong base and then with a carbonyl compound III O=CR3R4; thereafter, the product is reacted with the protic acid or with an alkyl halide IV R2Hal. If desired, the products are converted to the acid addition salts, or the stereoisomers or optically active enantiomers are resolved.
[US4876354A]
Patent IE-802548-L (IE)
Title: Device for dispensing medicaments
IPC: A61J7/00
Filed: 1980-12-05
Abstract: A device by which powdered medicaments can be orally or nasally administered to a patient comprises a body shell defining a portion of a chamber. A nozzle or mouthpiece is located at the forward end of the body shell. The body shell is open at the rear end. A sleeve is fitted on the outside of the rear end portion of the body shell and is rotatable and axially movable with respect to it. The sleeve has a rear wall which closes the open rear end of the chamber. A capsule retaining means extends through the rear wall of the sleeve into the chamber. The capsule retaining means has an external entry opening for a capsule at the rear of the sleeve. An abutment is fixed inside the chamber in such a position with respect to the retaining means that a capsule retained in the retaining means and projecting from it into the chamber will engage the abutment when the sleeve is rotated with respect to the body shell. This separates the projecting portion of the capsule from the remainder of the capsule. A grid or guard prevents the separated portion of the capsule from passing through the nozzle or mouthpiece. An air inlet opening extends through the rear wall of the sleeve into the chamber.
[US4353365A]
Patent IE-852649-L (IE)
Title: Pouring insert for a container
IPC: B65D47/06
Filed: 1985-10-25
Abstract: A pouring insert for a container closable by a cup-shaped dosing, metering or proportioning cap 4 is cup-shaped and has at least 3 uniformly, circumferentially distributed openings 11 extending into the side wall and into the base area 10, of the cup-shaped insert. The base area is convex in the direction of the open end of the insert, so providing an annular region 10 into which the openings, in the form of six slots, extend. The insert is sealingly located in the container neck by means either of an outwardly directed annular shoulder 6 and a sealing face 12 or by a outer skirt extending over the outside of the container neck (26, Figure 2A). The dosing cup nests within the pouring insert and screws either into the insert (Figure 2A) or into the neck exterior by means of an outer skirt 5. <IMAGE>
[GB2168946A]
Patent IE-872706-L (IE)
Title: Dihydropyridine derivatives
IPC: A61K31/4427
Filed: 1987-10-09
Abstract: Compounds of formula (I): <CHEM> in which:   Ar represents a phenyl group having at least one substituent selected from nitro, C1 - C4 haloalkyl, C1 - C4 haloalkoxy and cyano groups and halogen atoms;   R represents a C1 - C16 alkyl g                   roup, a C3 - C6 cycloalkyl group, a C1 - C4 alkyl group having a C3 - C6 cycloalkyl substituent, a C2 - C4 alkenyl group, a cinnamyl group or a C1 - C16 alkyl group having at least one substituent selected from hydroxy, C1 - C4 alkoxy and C1 - C4 alkylthio groups;   R<1> represents a hydrogen atom or a C1 - C3 alkyl group;   R <2a> and R <2b> are the same or different and each represents an unsubstituted phenyl group or a substituted phenyl group having at least one substituent selected from C1 - C4 alkyl, C1 - C4 alkoxy and C1 - C4 haloalkyl groups and halogen atoms;   one of R<3> and R<4> represents a methyl group and the other represents an amino group; and    n is an integer from 1 to 3; These compounds have a variety of valuable activities, including antihypertensive and Ca<+><+>-blocking activities, leading to their use for the treatment of circulatory and coronary disorders. They may be prepared by condensation of appropriate substituted benzylideneacetoacetic acid esters with appropriate amidinoacetic acid esters.
Patent IE-802739-L (IE)
Title: Herbicidal compositions
IPC: A01N47/22
Filed: 1980-12-30
Abstract: Synergistic herbicidal activity is displayed by a composition comprising the following two components: (a) a thiolcarbamate of the formula <CHEM> in which R<1> is selected from ethyl, benzyl, and p-chlorobenzyl, and when R<1> is ethyl, R<2> and R<3> are independently selected from C1-C6 alkyl and C5-C7 cycloalkyl, and when R<1> is benzyl or p-chlorobenzyl, R<2> and R<3> are independently selected from C1-C6 alkyl, or conjointly form C5-C7 alkylene; and (b) a phenylcarbarmoyloxycarbanilate of the formula <CHEM> in which R<4> is C1-C4 alkyl; and R<5> is selected from hydrogen and C1-C4 alkyl. The compositions may contain an inert carrier or diluent and optionally other active ingredients. They are applied post-emergence.
[EP0039535A2]
Patent NO-802821-L (NO)
Inventor: HAGEN ROLF
IPC: H04L25/38
Filed: 1980-09-24
Abstract: A circuit arrangement is provided for the transmission of digital signals between transmitting and/or receiving stations which operate with differing data transmission procedures and with different data formats. The signal transmission respectively occurs by way of a converter unit which, like the transmitting and receiving installations, is connected to a switching system. In the train of the transmission of digital signals from a transmitting installation operating with a lower data transmission rate to a receiving installation operating with a higher data transmission rate, the digital signals emitted by the appertaining transmitting installation are first collected in the converter unit in order to be emitted to the appertaining receiving installation only given the existence of a sufficient plurality of such signals. The transmission of digital signals from a transmitting installation operating with a higher data transmission rate to a receiving installation operating with a lower transmission rate occurs in data blocks. A respective plurality of data signals forming a block or, respectively, a signal group, is emitted together with a signal group end mark by the appertaining transmitting installation to the converter unit which then relays the digital signals to the appertaining receiving installation. In order to minimize control expense, the converter unit checks its signal acceptance capability upon the occurrence of the group end mark. Only given existence of a sufficient signal acceptance capability in the converter unit is an acknowledgment character emitted to the transmitting installation, the acknowledgment character then causing the transmission of signals forming a further signal group or block. The invention is preferably employed for signal transmission between telex stations and office printergram or teletex stations.