baber/WOPTO huggingface dataset:
Patent EP-0832296-B1 (EP)
Inventor: SHERIDAN PATRICK J
IPC: C12Q1/68
Filed: 1996-06-07
Granted: 2005-08-24
Abstract: The invention relates to a method of detecting a target oligonucleotide in a sample, comprising: (a) providing a support-bound capture probe (CP) comprising a region having a nucleic acid sequence C-3; (b) providing a label probe (LP) comprising a region having a nucleic acid sequence L-3, wherein the label probe contains a label moiety that is capable of generating a detectable signal; (c) providing a label extender (LE) comprising a region having first and second nucleic acid sequences, wherein the first LE nucleic acid sequences L-2 is complementary to nucleic acid sequences L-3 and the second LE nucleic acid sequence L-1 is complementary to a nucleic acid sequence in the target analyte; (d) providing a capture extender (CE) comprising a region having first and second nucleic acid sequences, wherein the first CE nucleic acid sequences C-2 is complementary to nucleic acid sequence C-3 and the second CE nucleic acid sequence C-1 is complementary to the second LE nucleic acid sequence L-1; (e) incubating the sample with the LE and the LP under first hybridizing conditions to form a first reaction mixture containing an LP/LE/target hybrid complex and an unbound LP/LE hybrid complex; (f) incubating the first reaction mixture with a solid support surface containing a surface-bound CE/CP hybrid complex under second hybridizing conditions, thereby forming a second reaction mixture containing a surface-bound LP/LE/target/CE/CP hybrid complex and an unbound LP/LE/target complex; (g) thereafter separating materials not bound to the solid support from those bound to the solid support; and (h) detecting the presence of label in the support-bound, LP/LE/target/CE/CP hybrid complex.
Patent EP-0863905-B1 (EP)
Inventor: MANO TAKASHI
IPC: C07D521/00
Filed: 1996-07-24
Granted: 2000-11-29
Abstract: PCT No. PCT/IB96/00744 Sec. 371 Date Jun. 29, 1998 Sec. 102(e) Date Jun. 29, 1998 PCT Filed Jul. 24, 1996 PCT Pub. No. WO97/11079 PCT Pub. Date Mar. 27, 1997The present invention provides a compound of formula (I): and a pharmaceutically acceptable salt thereof, wherein Ar is phenylene optionally substituted with halo, hydroxy, cyano, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 alkylthio, C1-C4 halo-substituted alkyl or C1-C4 halo-substituted alkoxy, X is -A-X1- or -X2-A-, where A is a direct bond or C1-C4 alkylene, and X1 is oxy, thio, sulfinyl or sulfonyl; Ar is phenylene, pyridylene or thienylene optionally substituted with halo, hydroxy, cyano, nitro, amino, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 alkylthio, C1-C4 halo-substituted alkyl, C1-C4 halo-substituted alkoxy, C1-C4 alkylamino or di(C1-C4)alkylamino; Y is CN or CONR1R2 wherein R1 and R2 are independently hydrogen or C1-C4 alkyl; and R is hydrogen or C1-C6 alkyl; W is C2-C3 alkylene, one carbon atom of which may be replaced by an oxygen atom. Further the invention provides a pharmaceutical composition for treating an inflammatory disease, allergy or cardiovascular diseases or the like in a mammalian subject which comprises a compound of formula (I) and a pharmaceutically acceptable carrier.
Patent EP-0861424-B1 (EP)
Inventor: JESTAEDT ALBRECHT
IPC: A61B5/00
Filed: 1996-11-12
Granted: 2001-10-04
Abstract: PCT No. PCT/EP96/04933 Sec. 371 Date May 18, 1998 Sec. 102(e) Date May 18, 1998 PCT Filed Nov. 12, 1996 PCT Pub. No. WO97/19332 PCT Pub. Date May 29, 1997The invention is directed to a method of operating a tympanic thermometer, in which a sensor (8) for detecting infrared radiation is arranged in a housing (1) having a radiation inlet (23). Associated with the sensor (8) is an electronic evaluation unit (13). For temperature measurement, the radiation inlet (23) is covered with a probe cover (5) transparent to infrared radiation. The condition of a missing probe cover (5) is indicated by an audible warning signal or a signal lamp (14) which are activated after the thermometer is turned on.
Patent EP-0874855-B1 (EP)
Inventor: WAGNER HELMUT
IPC: A61K31/43
Filed: 1996-11-14
Granted: 2004-02-18
Abstract: PCT No. PCT/EP96/05015 Sec. 371 Date May 11, 1998 Sec. 102(e) Date May 11, 1998 PCT Filed Nov. 14, 1996 PCT Pub. No. WO97/18216 PCT Pub. Date May 22, 1997Process for the production of alkali salts of clavulanic acid of formula by conversion of clavulanic acid into a pharmaceutically acceptable salt of clavulanic acid which is characterised in that the conversion is carried out in n-butanol or iso-butanol (2-methyl-1-propanol) as a solvent; and a potassium salt of clavulanic acid containing n-butanol or iso-butanol.
Patent EP-0865694-B1 (EP)
Inventor: REITBERGER PETER
IPC: H04B7/26
Filed: 1996-12-06
Granted: 1999-07-28
Abstract: L'invention se rapporte à un système destiné à établir automatiquement une liaison radio pour transmission de données entre deux ou plusieurs stations émettrices et réceptrices. Les données de bandes de fréquence et les méthodes d'accès utilisables chacune dans ces bandes sont mémorisées dans une mémoire. Un récepteur de recherche détecte l'ensemble des bandes de fréquence disponibles. Dans un dispositif d'évaluation, on détermine la bande de fréquence et la méthode d'accès. L'adresse de la station éloignée est transmise par l'intermédiaire dudit dispositif d'évaluation. Lorsque le récepteur de recherche de la station éloignée reçoit son adresse, la station éloignée connecte, dans cette bande de fréquence, conjointement avec la méthode d'accès autorisée, son récepteur de données à la réception, la transmission des données s'effectuant ensuite entre la station d'appel et la station éloignée.
Patent EP-0796591-B1 (EP)
Inventor: FUCHS KENNETH
IPC: G06F17/24
Filed: 1997-02-20
Granted: 2003-12-10
Abstract: A method and apparatus for displaying physiological signals acquired from a patient in a manner that allows for reliably associating with the physiological signals (40-46) acquired from the patient user generated message information (48-54). The method comprises the steps of, receiving at a central station (28) physiological signals acquired from a patient; and arranging a display portion of the central station to have at least one first display area (40-46) dedicated for displaying said physiological signals, and at least one second display area (48-54), located adjacent said first display area, dedicated for displaying a user generated message related to the physiological signals displayed in said first area. <IMAGE>
Patent EP-0848124-B1 (EP)
Inventor: AXMANN HORST
IPC: E05B65/10
Filed: 1997-10-28
Granted: 2002-03-20
Abstract: A pivot arm (35) controls lever arm (52) acting on a tumbler (37) association with the locking bolt (36) of a lock which can be withdrawn jointly with a follower-operated latch bolt (15). The arm is formed by a follower-operated connecting rod drive lever acting on a connecting rod connecting bar (4). The locking bolt is locked by displacement of the bar. Preferably, the pivot arm forms a control cam (50) which acts on a projection (51) on the lever arm to lift the tumbler. The pivot arm is driven in the opposite direction to the follower rotation.
Patent EP-0822022-B1 (EP)
Inventor: REICHELT WOLFGANG PROF-DR-ING
IPC: B22D41/50
Filed: 1997-07-22
Granted: 2002-05-22
Abstract: The spout is intended for pouring liquid metal, in particular, steel from a vessel into a mould of a continuous casting installation. It consists of an approximately pipe-shaped top section and a bottom section with wide and narrow sides comprising: a) the bottom end of the top section (11) has a broadened zone (12) surrounding the top end of the bottom section (21); b) in the entry zone of the bottom section a seal (31) is located between the top and bottom sections; c) the bottom section is provided with a support (40) in its entry zone; d) fixing elements (50) engage with the support of the bottom section and join the latter to the top section.
Patent EP-0892789-B1 (EP)
Inventor: BRIDGES ALEXANDER JAMES
IPC: A61P15/00
Filed: 1997-04-08
Granted: 2002-02-27
Abstract: The present invention relates to pyrimido [5,4-d] pyrimidine compounds of Formula II or a pharmaceutically acceptable salt thereof, wherein Q is and X, E1, E2, E3, R6 and p are as defined herein. The compounds of this invention are irreversible inhibitors of tyrosine kinases and are useful in the treatment of cancer, atherosclerosis, restenosis, endometriosis and psoriasis.
Patent EP-0923303-B1 (EP)
Inventor: HANSEN WILHELM
IPC: A23L11/00
Filed: 1997-05-17
Granted: 2001-11-07
Abstract: The description relates to a process for producing cheese, curd or yoghourt products from soya beans involving the steps; (a) preparation of soya milk from soya beans; (b) addition of vegetable sugar to the soya milk in the proportion of 1 to 5 wt %; (c) emulsifying vegetable fats and/or oils in a total proportion of some 15 wt % in the soya milk; (d) preparation of a culture cocktail with a pH between 3.8 and 4.5 by the addition of commercially available cheese cultures and animal lactose in a proportion of some 10 wt % of the vegetable sugar added in step (b) to the soya milk as in step (a); (e) addition of the culture cocktail to the soya milk as per step (c) to curdle it and ferment it as desired, and (f) subsequent ripening and final processing in the prior art manner to provide the desired cheese, curd or yoghourt product.
Patent EP-0906708-B1 (EP)
Inventor: EMILSSON STELLAN
IPC: H04L12/00
Filed: 1997-05-27
Granted: 2006-02-15
Abstract: L'invention concerne un terminal radiotéléphonique mobile destiné à un système de radiocommunication cellulaire numérique comprenant un certain nombre de stations de base connectées à un réseau public. Chaque station de base est conçue pour desservir un certain nombre de terminaux radio mobiles. Chaque terminal comporte un moyen de négociation qui permet la négociation initiale avec un fournisseur de services en vue de la fourniture d'une application de service demandée par un utilisateur de terminal; un moyen de commande permettant la commande dynamique des différents éléments de l'application de service, les interactions entre lesdits éléments et les interactions entre l'application de service et un réseau support; et un moyen d'accès par répartition de code qui permet aux différents utilisateurs de partager une ressource radio. Le moyen d'accès par répartition de code peut utiliser l'AMCR ou le COFDM.
Patent EP-0918781-B1 (EP)
Inventor: ZHANG XUMU
IPC: C07D333/46
Filed: 1997-06-13
Granted: 2004-02-18
Abstract: The present invention relates to rigid chiral ligands usefull in making catalysts for asymmetric synthesis. More particularly, the present invention relates to new monodentate and bidentate cyclic chiral phosphine ligands which are formed into catalysts to provide high selectivity of the enantiomeric structure of the end-product.
Patent EP-0912383-B1 (EP)
Inventor: MUELLER RICHARD
IPC: B61B13/00
Filed: 1997-07-17
Granted: 2001-10-24
Abstract: In a travelling trolley assembly, the two side frame bars (6, 7) which extend on either side of the running rail (2) are connected to one another via two connecting columns (8). The connecting columns (8) are smooth and cylindrical on the outside are fitted into receiving or sliding-guidance devices which are formed in the side frame bars (6, 7) below the running rail (2). In order to adjust the distance between the two side frame bars (6, 7) and to fix the distance which has been set, receiving devices, through which a threaded rod (46) which is parallel to the connecting column (8) passes, are situated in the vicinity of the connecting columns (8). The distance is adjusted and fixed with the aid of screw threads (94, 95), preferably lock nuts, which rest on the connecting rod (46). This type of fixing arrangement does not damage the shape of the guide columns (8), so that dismantling is easy to carry out at any time.
Patent EP-0918630-B1 (EP)
Inventor: CLARKE PETER ARTHUR
IPC: B32B21/10
Filed: 1997-08-13
Granted: 2000-07-26
Abstract: A flexible, water-resistant laminate is produced by bonding a wood veneer by means of a waterproof or water-resistant adhesive to a web made wholly or principally of waterproof or water-resistant fibres. The web is preferably a non-woven generally discontinuous web (e.g. spun laid) which allows the adhesive readily to permeate the web during formation of the laminate, and which is strong, flexible and water-resistant to withstand the forces sustained during sanding and wrapping.
Patent EP-1015964-B1 (EP)
Inventor: CHRISTIANSON DAVID
IPC: G06F17/30
Filed: 1997-09-22
Granted: 2003-11-26
Abstract: This invention provides assistance to a user in accessing network attached information sources. In one aspect, the invention is a method for intelligently routing a user query to information sources relevant to that query, extracting relevant data fields from received responses, and intelligently presenting the extracted data in order of estimated relevance. The system of this invention implements one or more steps of the method in a centralized or distributed manner on one or more network attached computers. Further, this invention provides a novel language and implementation that facilitates easily written and maintained descriptions of information source query and response formats.
Patent EP-0938453-B1 (EP)
Inventor: CHRISTENSEN TERKEL CHRISTIAN
IPC: C02F9/00
Filed: 1997-10-09
Granted: 2002-05-08
Abstract: A process for the removal of dissolved metals and/or metalloids from an aqueous medium having a high content of salt wherein the aqueous medium in the presence of manganese (II) ions and an oxidation agent is passed through a particulate carrier material having a specified density, initial average grain size and flow rate, so as to fluidize carrier material particles in the aqueous medium, and whereby the coated material particles thereby formed are separated from the aqueous medium.
Patent EP-0938808-B1 (EP)
Inventor: SIH GILBERT C
IPC: H04M1/725
Filed: 1997-11-13
Granted: 2006-04-05
Abstract: A novel and improved method and apparatus for providing an interface to a digital wireless telephone system compatible with standard analog wire line telephones and analog wire line fax machines is disclosed. During a telephone call, a fax detector (11) monitors the incoming data for fax signals. If a fax is detected, the data processor (12) switches from processing the data as if it were voice to processing it as fax. In addition, the remote station is sent a signal notifying it to process the data as fax rather than voice. The fax detector (11) operates by detecting the preamble of a V.21 message, present at the beginning of every fax call. Energy is measured in both frequencies of the BFSK signals. A decision is made by analyzing these energies and locating a specific pattern which repeats itself a sufficient number of times.
Patent EP-0901341-B1 (EP)
Title: Bend-responsive catheter
Inventor: BEN-HAIM SHLOMO
IPC: A61B5/296
Filed: 1997-12-31
Granted: 2005-02-16
Abstract: PCT No. PCT/IL97/00448 Sec. 371 Date Apr. 12, 1999 Sec. 102(e) Date Apr. 12, 1999 PCT Filed Dec. 31, 1997 PCT Pub. No. WO98/29032 PCT Pub. Date Jul. 9, 1998An invasive probe apparatus includes a flexible, elongate probe having a distal end for insertion into the patient's body, first and second position sensors in a fixed, known relation to the distal end for generating signals responsive to their respective position coordinates and at least one contact sensor along a radial surface of the probe for generating a signal representing its contact with body tissue to be ablated by electrodes on the probe.
Patent EP-0939736-B1 (EP)
Title: Tablettenprüfgerät
Inventor: BRACHER MARTIN
IPC: B07C5/02
Filed: 1997-11-07
Granted: 2001-04-25
Abstract: Die Erfindung betrifft ein Tablettenprüfgerät mit einer schneckenförmigen Vibrationsförderer- und Vereinzeleinheit (1), einer Positioniereinheit (2) mit einem Transportrechen (7) und einer Orientierungseinheit (3) zwischen den beiden erstgennanten, die insbesondere als Vibrationslinearförderer aufgebaut ist. Eine Sensoranordnung triggert den Transportrechen (7) und erlaubt das automatische Ausscheiden von Tablettenbruchstücken über eine Bruchstückfalle (9).
Patent EP-0896814-B1 (EP)
Inventor: GAUSE ENNO DR RER NAT
IPC: A61F13/15
Filed: 1998-08-10
Granted: 2002-11-13
Abstract: The disposable nappy or incontinence pants are formed from a main section (2) comprising the front, back and centre portions (8,10,12), to be advanced on a longitudinal line (4). The main section (2) is folded on a line (14) at right angles to the longitudinal line (4), so that the front (8) and rear (10) sections are over each other with their edges (16,18) flush over each other. Two fabric webs (22,24), for the belt-shaped hip sections (34), are fed along the line of the folded main section. The fabrics (22,24) are of a stretch or elasticised material, fed stretched under tension, to move over or under each folded main section. One fabric (20) is secured to the front section (8) and the other fabric (22) is fixed to the rear section (10) of the folded main section. The two fabrics (20,22) are durably bonded together across their feed line, and the movement line of the folded main section, at a gap from the main section. The fabrics are cut across their feed direction and the movement line of the folded main section, to give separated pants.
Patent EP-1002753-B1 (EP)
Inventor: STICKELBROCKS KARL
IPC: G09F3/02
Filed: 1998-11-18
Granted: 2001-04-04
Abstract: Several units (2,2a,2b) are arranged adjacently on a tape. Defined separation points (3b) are provided so that the units can be separated from each other. The tape (1) has a carrier layer (4) on whose surface a number of removable labels, tags, or access control passes (5) are arranged, forming a unit together with the carrier layer. The carrier layer has an additional separating line (6), transverse to the tape movement direction, and displaced w.r.t. the defined separation point. A magnetic or electronic storage device may be integrated into the label, tag or access control pass.
Patent EP-1002465-B1 (EP)
Inventor: FASSIN KLAUS
IPC: A23L29/212
Filed: 1998-11-20
Granted: 2001-08-16
Abstract: In the production of fruit gum confectionery by casting a heated mixture of sweetener, water, gelling agent, acid, fruit and plant extracts and aromas in molds and removing the gums set by cooling, (a) the gelling agent is a mixture of pectin and modified starch and (b) the unmolded gums are dried above 40 degrees C.
Patent EP-0938846-B1 (EP)
Inventor: THARRAULT JEAN-FRANCOIS
IPC: A21D13/00
Filed: 1998-02-13
Granted: 2004-04-14
Abstract: Frozen or refrigerated toast comprising at least one slice of bread and a topping or filling has a soft crumb and crusty crust after reheating in a microwave oven. An Independent claim is also included for the production of toast as above by baking bread so that the moisture loss is 17-22%, keeping the bread at 4-10 degrees C for 1-7 days, slicing the bread, grilling one of the slices, distributing a layer of fatty material over the slice, applying a topping, packaging the toast in a plastic or cardboard package, and storing the product at refrigerator or freezer temperature.
Patent EP-0877132-B1 (EP)
Inventor: AVVANZINI UGO
IPC: E05C9/02
Filed: 1998-05-08
Granted: 2006-10-04
Abstract: A device (1) for manually controlling handles, of the type comprising a body (2) for the containment of motion transmission means able to be inserted in a chamber with longitudinal development presented by a section bar of a movable frame; the device (1) presents on the containment body (2) means able to allow the association of a handle to the section bar, means comprising at least one pair of seats (7) distanced from each other by a value (H7) ranging from 22 and 30 mm. <IMAGE>
Patent EP-0979760-B1 (EP)
Title: Procede de fabrication de garnitures et garniture pour toit de vehicule avec fonctions integrees
Inventor: CREMADES SCHULZ ALBERTO
IPC: B29C51/12
Filed: 1998-02-27
Granted: 2002-11-06
Abstract: L'invention concerne une garniture constituée d'une feuille support (4) pouvant être déformée dans un moule afin de définir des emboutis ou logements (8) conçus pour recevoir les différentes fonctions (5). Ledit support (4) est combiné au reste des couches (9) constituant la garniture et formées de manière à s'adapter au support (4) afin de boucher les embouchures des logements (8). Le procédé consiste à emboutir le support (4), à loger dans les emboutis (8) les fonctions (5), à emboutir dans une autre presse ou simultanément dans la même le reste des couches (9) et à fixer finalement cet ensemble à l'aide d'adhésifs intermédiaires adéquats.
Patent EP-1017408-B1 (EP)
Inventor: HAUPTMAN JONATHAN BRIAN
IPC: A61K38/00
Filed: 1998-01-29
Granted: 2005-04-13
Abstract: L'invention concerne l'utilisation d'un inhibiteur des lipases gastro-intestinales pour réaliser des médicaments administrés par voie orale qui sont efficaces contre le diabète sucré type II, ainsi que les médicaments ainsi obtenus.
Patent EP-0983363-B1 (EP)
Inventor: ALESSI DARIO RENATO
IPC: C12N1/15
Filed: 1998-03-16
Granted: 2005-11-23
Abstract: The present invention provides for isolated polynucleotides encoding a human 3-phosphoinositide-dependent protein kinase, and vectors and host cells comprising the isolated polynucleotides.
Patent EP-0971645-B1 (EP)
Inventor: KHOSRAVI FARHAD
IPC: A61F2/06
Filed: 1998-03-18
Granted: 2006-11-02
Abstract: A prosthesis is provided for treatment of aneurysms, occlusive disease of vessels and body organs, and arterio-venous fistulas, comprising an expandable coiled sheet portion having a biocompatible graft affixed thereto. The graft material, preferably a polytetrafluoroethylene ("PTFE") or polyesther material, is affixed to the coiled sheet portion by sintering, suturing, or bonding using a biocompatible adhesive. The coiled sheet portion comprises a lattice formed from a biocompatible material, and may include one or more rows of locking teeth adjacent one edge of the coiled sheet that interengage openings in an opposing edge of the coiled sheet portion to retain the prosthesis at a desired expanded diameter. The prosthesis has a small delivery profile, making it suitable for use in a variety of body vessels. Methods of making and deploying the prosthesis are also provided.
Patent EP-0971972-B1 (EP)
Inventor: MAIGNAN JEAN
IPC: A61K8/72
Filed: 1998-03-26
Granted: 2004-04-14
Abstract: A polymer chosen from hyperbranched polymers and dendrimers containing at least one functional group of formula (I):in which: Y is chosen from an oxygen atom and an NH group; A is chosen from linear, branched and cyclic, saturated and unsaturated C1-C12 alkanediyl groups, wherein said alkanediyl groups may or may not be interrupted by at least one heteroatom, and further wherein said alkanediyl group may or may not be substituted with at least one function chosen from: -amino groups NH2 and salts thereof with inorganic acids or organic acids, -acylamino groups NH-COR, in which R is chosen from linear, branched and cyclic, saturated and unsaturated C1-C10 alkyl groups, -C1-C10 alkylamino groups, -carboxylic acid, and -C1-C10 esters; and X is chosen from nucleophilic groups, methods for preparing the polymer and using the polymer as an antioxidant is disclosed.