Patent EA-000744-B1 (EA)
Title: Herbicidal composition containing 4-benzoylisoxazoles and a hydroxybenzonitrile
Inventor: ANDERSON-TAYLOR GORDON
IPC: A01N37/34
Filed: 1996-12-19
Abstract: 1. A method for the control of the growth of weeds at a locus which comprises applying to the locus a synergistic herbicidally effective amount of: (a) a 4-benzoylisoxazole herbicide; and (b) bromoxynil, which is 3,5-dibromo-4-hydroxybenzonitrile, or ioxynil, which is 4-hydroxy-3,5-diiodobenzonitrile, an agriculturally acceptable salt or ester thereof, or a mixture thereof. 2. A method according to claim 1 in which the 4-benzoylisoxazole is a compound of formula (I)   wherein R is hydrogen or -CO2R<3>; R<1> is cyclopropyl; R<2> is selected from halogen, -S(O)pMe and C1-C6 alkyl or haloalkyl; n is two or three; p is zero, one or two; and R<3> isC1-C4 alkyl. 3. A method for the control of the growth of weeds at a locus which comprises applying to the locus a synergistic herbicidally effective amount of: (a) a 4-benzoylisoxazole of formula (I)   wherein R is hydrogen or -CO2R<3>; R<1> is cyclopropyl; R<2> is selected from halogen, -S(O)pMe and C1-C6 alkyl or haloalkyl; n is two or three; p is zero, one or two; and R<3> is C1-C4 alkyl; and (b) bromoxynil, which is 3,5-dibromo-4-hydroxybenzonitrile, or an agriculturally acceptable salt or ester thereof. 4. A method according to claim 1, 2 or 3 using an application rate of from 5 g to 500 g of (a) and from 30g to 600g acid equivalent of (b) per hectare. 5. A method according to any one of claims 1 to 4 using bromoxynil or ioxynil as an agriculturally acceptable metal or amine salt, or an agriculturally acceptable ester thereof with an alkanoic acid containing from 2 to 10 carbon atoms. 6. A method according to any one of claims 2 to 5 wherein, in formula (I), n is three and the groups (R<2>)n occupy the  2, 3 and 4-positions of the benzoyl ring, or in which n is two and the groups (R<2>)n occupy the 2 and 4- positions of the benzoyl ring. 7. A method according to any one of claims 2 to 6 wherein, in formula (I), one of the groups R<2> is -S(O)pMe, wherein p is as defined in claim 2. 8. A method according to any one of claims 2 to 7 wherein the compound of formula (I) is 5-cyclopropyl-4-(2-methylsulphonyl-4-trifluoromethyl)benzoylisoxazole. 9. A method according to any one of claims 2 to 7 wherein the compound of formula (I) is ethyl 3-[5-cyclopropyl-4-(3,4-dichloro-2-methylsulphenyl)benzoylisoxazole]-carboxylate. 10. A method according to any one of claims 1 to 9 by post-emergence application. 11. A method according to any one of claims 1 to 10 in which the locus is an area used, or to be used, for growing maize or winter cereals. 12. A composition comprising a synergistic herbicidally effective amount of: (a) a 4-benzoylisoxazole derivative as defined in any one of claims 1,2 or 6 to 9; and (b) bromoxynil, which is 3,5-dibromo-4-hydroxybenzonitrile, or ioxynil, which is 4-hydroxy-3,5-diiodobenzonitrile, an agriculturally acceptable salt or ester thereof, or a mixture thereof, in association with one or more herbicidally-acceptable diluents or carriers and/or surface-active agents. 13. A herbicidal composition comprising a synergistic herbicidally effective amount of. (a) a 4-benzoylisoxazole of formula (I)   wherein R is hydrogen or -CO2R<3>, R<1> is cyclopropyl; R<2> is selected from halogen, -S(O)pMe and C1-C6 alkyl or haloalkyl, n is two or three; p is zero, one or two; and R<3> is C1-C4 alkyl; and (b) bromoxynil, which is 3,5-dibromo-4-hydroxybenzonitrile, or an agriculturally acceptable salt or ester thereof. 14. A composition according to claim 12 or 13 comprising from 1:120 to 16.7:1 wt/wt of (a): (b) acid equivalent. 15. A product comprising a herbicidally effective amount of: (a) a 4-benzoylisoxazole derivative of formula I as defined in any one of claims 1, 2 or 6 to 9; and (b) bromoxynil, which is 3,5-dibromo-4-hydroxybenzonitrile, or ioxynil, which is 4-hydroxy-3,5-diiodobenzonitrile, an agriculturally acceptable salt or ester thereof, or a mixture thereof; as a combined preparation for simultaneous, separate or sequential use at a locus.