baber/WOPTO huggingface dataset:
Patent CA-2994917-A1 (CA)
Title: Derives substitues par un 3-indole, compositions pharmaceutiques et leurs procedes d'utilisation
Inventor: NINKOVIC SACHA
IPC: C07D417/04
Filed: 2016-08-04
Abstract: Cette invention concerne un composé de Formule (I), ou des énantiomères, des sels ou des solvates de ceux-ci pharmaceutiquement acceptables. L'invention concerne également l'utilisation des composés de Formule (I) à titre d'inhibiteurs de TD02, notamment pour le traitement et/ou la prévention du cancer, des troubles neurodégénératifs tels que la maladie de Parkinson, la maladie d'Alzheimer et la maladie de Huntington, des infections virales chroniques telles que les infections à VHC et VIH, la dépression et l'obésité. Un procédé de préparation des composés de Formule (I) est en outre décrit.
Patent CA-2994985-A1 (CA)
Inventor: OVELAND NILS PETTER
IPC: A61M25/02
Filed: 2015-08-28
Abstract: Dispositif de fixation de tube (1) pour maintenir un tube (2) dans le corps d'un mammifère dans une position fixée de manière amovible, ledit dispositif de fixation de tube (1) comprenant un élément de réception de tube (3) conçu pour recevoir le tube (2); un élément de fixation (4) relié à l'élément de réception de tube (3) et conçu pour fixer amovible le tube (2) lorsque celui-ci est logé dans l'élément de réception de tube (3); et un élément support (5) fixé à l'élément de réception de tube (3) et conçu pour être disposé sur une zone de surface du corps du mammifère. L'invention est caractérisée en ce que l'élément support (5) comporte une structure en couches (16) composée d'une couche ductile (20) contenant un matériau ductile, conçue pour être mise en forme par un praticien pour se conformer à la forme tridimensionnelle de la zone de surface du corps du mammifère.
Patent CA-2997525-A1 (CA)
Inventor: KISHIMOTO NAOKI
IPC: B05B5/04
Filed: 2016-07-20
Abstract: Provided is a rotary atomization type painting device having an atomization head having an extended life obtained by a means other than a coating film. In a rotary atomization type painting device, the life of an atomization head can be extended by a means other than a coating film. A rotary atomization type painting device 1 is provided with an atomization head 2 to which paint is supplied from a paint supply machine 3. The atomization head 2 has: an outer member 4 comprising cylindrical body having a truncated circular conical shape; and an inner member 5 disposed inside the outer member 4. The inner member 5 has an annular protrusion 38 protruding toward a large diameter-side opening 7. Paint is delivered to the root of the annular protrusion 38 from a plurality of delivery holes 49 in the inner member 5. The angle ?1 of the direction of delivery through the delivery holes 49 measured relative to an axis Co and the angle ?2 of the inner surface of the annular protrusion 38 relative to the axis Co are set to be the same at the position of the root in the axial direction.
Patent CA-2997838-A1 (CA)
Title: Biomarqueurs urinaires du lupus erythemateux aigu dissemine et de la nephropathie lupique
Inventor: WITHER JOAN E
IPC: G01N33/564
Filed: 2015-10-07
Abstract: L'invention concerne un panel de biomarqueurs du lupus érythémateux aigu disséminé (LEAD) et/ou de la néphropathie lupique (NL) comprenant un support solide et au moins deux agents de détection de biomarqueur, chaque agent de détection de biomarqueur étant spécifique d'un biomarqueur cible correspondant choisi dans un groupe de biomarqueurs cibles énumérés ici ; ainsi que des procédés permettant de mesurer les niveaux de biomarqueur, de prédire, de pronostiquer, de surveiller et de stratifier les patients atteints de LEAD, y compris de LEAD actif sans LN et de LEAD actif avec LN.
Patent CA-2999393-A1 (CA)
Title: Apparatus, method or computer program for generating a sound field description
Inventor: HABETS EMANUEL
IPC: H04R3/00
Filed: 2017-03-10
Abstract: An apparatus for generating a sound field description having a representation of sound field components, comprises a direction determiner (102) for determining one or more sound directions for each time-frequency tile of a plurality of time-frequency tiles of a plurality of microphone signals; a spatial basis function evaluator (103) for evaluating, for each time-frequency tile of the plurality of time-frequency tiles, one or more spatial basis functions using the one or more sound directions; and a sound field component calculator (201) for calculating, for each time-frequency tile of the plurality of time-frequency tiles, one or more sound field components corresponding to the one or more spatial basis functions evaluated using the one or more sound directions and a reference signal for a corresponding time-frequency tile, the reference signal being derived from one or more microphone signals of the plurality of microphone signals.
Patent CA-3001639-A1 (CA)
Title: Outil de compression concu en tant que plaque de compression
Inventor: ESPE ROLF
IPC: B30B15/06
Filed: 2016-11-08
Abstract: L'invention concerne un outil de compression pour le revêtement de panneaux en matériau dérivé du bois dans des presses à chaud hydrauliques, conçu en tant que plaque de compression (1) en plastique résistant aux températures élevées de type poly(étheréthercétone) (PEEK) et dont la surface (2) est structurée ou lisse et présente divers niveaux de brillance.
Patent CA-3003321-A1 (CA)
Inventor: SWANTNER MICHAEL J
IPC: A61M5/145
Filed: 2016-10-28
Abstract: A pressure jacket for use with a fluid injector may have a pressure jacket body having a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a pressure jacket longitudinal axis. The pressure jacket may further have at least one resiliently deflectable retaining member having a first segment attached to the pressure jacket body and a second segment protruding from the first segment toward the distal end of the pressure jacket body and deflectable relative to the first segment. The pressure jacket may further have at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member may interact with a housing of the fluid injector when the pressure jacket is connected to the housing to deflect the at least one resiliently deflectable retaining member upon rotation of the pressure jacket.
Patent CA-3003596-A1 (CA)
Inventor: KIM PETER C
IPC: A61B17/28
Filed: 2016-10-31
Abstract: A method is provided for making an appendage of a soft surgical tool, including: receiving a set of mechanical constraints for a surgical procedure; calculating a set of articulation states based on the set of mechanical constraints; generating a plurality of print commands for printing an appendage configured to form the set of articulation states based on the calculation; and printing an appendage based on the plurality of print commands. Multiple printed appendages can be formed into an orienting assembly.
Patent CA-3006100-A1 (CA)
Inventor: TORBERSON NATHAN LEE
IPC: F16H1/24
Filed: 2018-05-23
Abstract: A rotary machine includes a vessel that defines an interior for receiving materials. The vessel is mounted to rotate about an axis of rotation that extends through the vessel. The rotary machine also includes a sprocket mounted circumferentially about an exterior of the vessel so as to encircle the axis of rotation of the vessel. The sprocket includes a plurality of sprocket teeth. The sprocket defines a sprocket pitch diameter and a sprocket addendum diameter. The rotary machine also includes a drive wheel that intermeshes with the sprocket for driving rotation of the vessel about the axis of rotation of the vessel. The drive wheel includes a plurality of rollers that are received between the sprocket teeth of the sprocket. The rollers each have a roller diameter and a roller axis. The rollers are rotatable about their respective roller axes. The drive wheel has a drive wheel pitch diameter defined by the roller axes. The sprocket addendum diameter is equal to the sprocket pitch diameter plus a distance equal to at least 1.0 times the roller diameter.
Patent CA-3007331-A1 (CA)
Inventor: DOMINGUEZ HELBERT DAVID ALMEIDA
IPC: A23P20/20
Filed: 2016-12-15
Abstract: A method for manufacturing a food product includes depositing a first foodstuff; transporting the first foodstuff in a first driven direction; depositing a second foodstuff upon a portion of an upper surface of the first foodstuff; transporting the first foodstuff with the second foodstuff deposited thereupon in the first driven direction; separating the first foodstuff with the second foodstuff metered thereupon into a plurality of sheet segments; serially transporting each sheet segment of the plurality of sheet segments from the first driven direction to a second driven direction that is transverse to the first driven direction; compressing the serially transported sheet segments for forming a plurality of thickness segments including the first foodstuff and the second foodstuff that define anelongated, food product body; separating the elongated, food product body into a plurality of food product body units; and finishing the plurality of food product body units.
Patent CA-3007980-A1 (CA)
Title: Compositions a base de cellules immunitaires et leurs methodes d'utilisation
Inventor: ADUSUMILLI PRASAD S
IPC: A61K35/17
Filed: 2016-12-08
Abstract: L'invention concerne des cellules qui sont des cellules immunoinhibitrices, lesquelles cellules expriment par voie recombinante une forme négative dominante d'un inhibiteur de la réponse immunitaire à médiation cellulaire de la cellule. Dans certains modes de réalisation, la cellule immunoinhibitrice est un lymphocyte T régulateur. Selon un autre aspect, la présente invention concerne un lymphocyte T régulateur qui exprime par voie recombinante une forme négative dominante d'un inhibiteur de la réponse immunitaire à médiation par les lymphocytes T régulateurs. Les cellules peuvent être sensibilisées à un antigène qui est la cible d'une réponse immunitaire pathologique associée à un trouble d'origine immunologique. L'invention concerne également des méthodes d'utilisation desdites cellules pour traiter un trouble d'origine immunologique chez un sujet qui en a besoin.
Patent CA-3008284-A1 (CA)
Inventor: MUMM JOHN BRIAN
IPC: A61K38/00
Filed: 2016-12-28
Abstract: L'invention concerne des méthodes de traitement de sujets ayant une maladie, une pathologie ou un trouble lié à un cancer ou de prévention de l'apparition d'une telle maladie, pathologie ou trouble, par administration d'une PEG-IL-10 en combinaison avec un agent IL-12.
Patent CA-3008453-A1 (CA)
Inventor: BECKMAN BRIAN C
IPC: B64C11/24
Filed: 2016-12-14
Abstract: Sounds are generated by an aerial vehicle (101) during operation. For example, the motors and propellers (102) of an aerial vehicle (101) generate sounds during operation. Disclosed are systems, methods, and apparatus for actively adjusting the position of one or more propeller blade treatments (202) of a propeller blade (200) of an aerial vehicle (101) during operation of the aerial vehicle (101). For example, the propeller blade (200) may have one or more propeller blade treatments (202) that may be adjusted between two or more positions. Based on the position of the propeller blade treatments (202), the airflow over the propeller (102) is altered, thereby altering the sound generated by the propeller (102) when rotating. By altering the propeller blade treatments (202) on multiple propeller blades (200) of the aerial vehicle (101), the different sounds generated by the different propeller blades (200) may effectively cancel, reduce, and/or otherwise alter the total sound generated by the aerial vehicle (101).
Patent CA-3010244-A1 (CA)
Inventor: TSUKAGOSHI IKUO
IPC: H04N21/438
Filed: 2016-12-19
Abstract: There is provided a transmission apparatus including circuitry configured to generate a video stream that switches between transmission video data of a plurality of types. Each of the plurality of types of the transmission video data has a different predetermined opto-electronic conversion characteristic. The circuitry is further configured to insert identification information into the video stream. The identification information indicates the type of one of the transmission video data included in the video stream.
Patent CA-3012133-A1 (CA)
Inventor: DAI XING
IPC: C07C275/40
Filed: 2017-02-08
Abstract: Overexpression of indoleamine 2,3-dioxygenase (IDO) was observed in various tumors, which is thought to enable tumor cells escape from immunosurveillance, and is also associated with other diseases such as viral infections and Alzheimer's. Accordingly, IDO is a promising target in cancer as well as in other diseases such as infectious diseases and Alzheimer's. The present disclosure provides compounds of Formula (I) that inhibit IDO such as IDOL These compounds may be useful in treating a disease associated with IDO, for example, cancer or an infectious disease (e.g., viral or bacterial infectious diseases). The present disclosure also provides pharmaceutical compositions, kits, methods, and uses including or using compounds of Formula (I).
Patent CA-3014597-A1 (CA)
Inventor: PIERSON PAUL RICHARD
IPC: A61C9/00
Filed: 2012-06-22
Abstract: Un matériau pour empreinte à gestion des tissus et un procédé dapplication dans le sillon dun patient, dans lequel le matériau pour empreinte à gestion des tissus fait partie de limpression dentaire définitive fabriquée lors de la fabrication dun dispositif dentaire, comme une couronne sont décrits ici.
Patent CA-3017356-A1 (CA)
Title: Proteines de fusion se liant a un antigene et ayant des domaines hsp70 modifies
Inventor: BRAUNS TIMOTHY
IPC: C07K14/35
Filed: 2017-03-10
Abstract: L'invention concerne des protéines de fusion comprenant un domaine de liaison à l'antigène fusionné à une protéine de choc thermique 70 modifiée. L'invention concerne en outre des procédés d'utilisation des protéines de fusion pour induire une réponse immunitaire à des antigènes et pour traiter des maladies associées à des antigènes.
Patent CA-3018794-A1 (CA)
Title: Use of il-23 antibodies for treating generalized pustular psoriasis
Inventor: BAUM PATRICK
IPC: A61P17/06
Filed: 2017-04-13
Abstract: This invention generally relates to methods for the treatment of IL-23 related diseases, in particular inflammatory diseases, such as psoriasis or psoriatic arthritis, utilizing anti-IL-23 A antibodies.
Patent CA-3019956-A1 (CA)
Inventor: FARLEY DANIEL G
IPC: G08B29/02
Filed: 2017-04-07
Abstract: L'invention concerne un serveur de données de disponibilité de premier intervenant servant à surveiller au moins un paramètre de disponibilité d'un dispositif contrôlable, pouvant être obtenu auprès d'un capteur qui peut être couplé au dispositif contrôlable, le capteur étant configuré pour détecter une valeur actuelle du ou des paramètres de disponibilité du dispositif contrôlable. Le serveur comprend une interface de communication configurée pour recevoir des données envoyées par le capteur, les données correspondant à la valeur actuelle d'au moins un paramètre de disponibilité du dispositif contrôlable, et un processeur configuré pour déterminer si la valeur actuelle du ou des paramètres de disponibilité du dispositif contrôlable satisfait à au moins une règle définie par l'utilisateur, déterminer un état de dispositif indiquant si la valeur actuelle du ou des paramètres de disponibilité du dispositif contrôlable a satisfait à la règle définie par l'utilisateur, l'interface de communication étant en outre configurée pour envoyer une indication de l'état de dispositif à un écran de contrôle.
Patent CA-3020483-A1 (CA)
Title: Inspection d'une chaussure avec une camera thermique
Inventor: MANNESCHI ALESSANDRO
IPC: G01N21/84
Filed: 2018-10-10
Abstract: L'invention concerne un procédé d'inspection d'une chaussure portée par un pied d'un individu comprenant les étapes suivantes : - acquérir (S1) une image thermique de la chaussure lorsqu'elle est portée par un pied de l'individu à l'aide d'une caméra thermique, - déterminer (S2), à partir de l'image thermique de la chaussure, une limite inférieure du pied de l'individu, - déterminer (S3) une position de la chaussure par rapport à la caméra thermique au moment de l'acquisition de l'image thermique, et - déduire (S4) de la position de la chaussure par rapport à la caméra et de la limite inférieure du pied, une distance entre la face inférieure de la semelle et la face inférieure du pied de l'individu.
Patent CA-3022873-A1 (CA)
Inventor: WIDNER ERNEST BARFIELD
IPC: G06K19/06
Filed: 2017-05-03
Abstract: La présente invention concerne un procédé de suivi d'une boîte et la corrélation d'une caractéristique de qualité de la boîte à une efficacité d'équipement globale d'une ligne d'emballage qui manipule la boîte pendant un processus d'emballage d'un produit qui consiste : à un premier emplacement, associant un identifiant unique avec une forme pré-bâtie de la boîte, à capturer au moins une caractéristique de qualité de la boîte, et à stocker ladite caractéristique de qualité et l'identifiant unique associé dans une base de données ; à déplacer la forme pré-bâtie de la boîte vers un second emplacement ; au niveau du second emplacement, à convertir la forme pré-bâtie de la boîte en une boîte bâtie, à manipuler la boîte bâtie à travers la ligne d'emballage, et dans un cas où la boîte bâtie est impliquée dans une interruption dans la ligne d'emballage corrélant l'identifiant unique de la boîte bâtie associée avec l'interruption associée et à sauvegarder un enregistrement de l'interruption et de l'identifiant unique dans le support d'informations.
Patent CA-3023648-A1 (CA)
Inventor: LIU LIPING
IPC: A61K31/4375
Filed: 2016-11-10
Abstract: A composition, and an application and pharmaceutical preparation thereof. The invention provides a plurality of novel compositions and preparations comprising a berberine in combination with EPA and DHA, and an application thereof for treating a plurality of diseases. The composition is used for treating, alleviating, or preventing a plurality of diseases or disorders including metabolic diseases or disorders such as dyslipidemia, hyperglycemia, hypertriglyceridemia, hyperlipidemia, diabetic dyslipidemia, diabetic hyperlipidemia, hyperlipidemia in a statin-intolerant patient, diabetes, hypercholesterolemia complications of diabetes, or obesity. The composition can also be used for treating and/or preventing atherosclerosis, heart disease, neurodegenerative disease, inflammation, cancer, and a plurality of liver diseases or disorders such as fatty liver, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, cholestatic liver disease, or hepatic graft-versus-host disease. In addition, the composition can be used to improve liver functions in chronic viral hepatitis and alcoholic liver disease.
Patent CA-3025683-A1 (CA)
Inventor: FRATTALONE JOHN
IPC: E04B1/18
Filed: 2016-05-31
Abstract: A kit that includes multiple rectilinear elongate polygonal elements having five unique shapes, four of which are concave polygonal elements. In some examples, when arranged with respect to one another, the elements of the kit form a girih strapwork pattern. In one aspect, respective elements in a kit may include bezels or boarders along longer sides to enhance an over/under weaving effect of the girih strapwork pattern. In other aspects, one or more elements may be formed as a tray, and some of the trays may include various components or materials disposed in the tray (e.g., architectural surface materials, biological systems, various electronic components) to provide for a variety of creative designs and structural/sculptural installations for built environments. In some implementations, one or more such trays may have beveled rims so as to appear light and thin when viewed.
Patent CA-3027680-A1 (CA)
Title: Dispositif de traitement d'informations, dispositif de reception et procede de traitement d'informations
Inventor: IGARASHI TATSUYA
IPC: H04N21/422
Filed: 2018-04-06
Abstract: L'invention concerne un appareil de réception comprenant un circuit de traitement qui est configuré pour recevoir une commande vocale relative au contenu d'un utilisateur durant la présentation du contenu à l'utilisateur. Le circuit de traitement est configuré pour transmettre la commande vocale à un système de serveur en vue d'un traitement. Le circuit de traitement est configuré pour recevoir une réponse à la commande vocale du système de serveur. La réponse à la commande vocale est générée d'après la commande vocale et les informations de contenu permettant d'identifier le contenu relatif à la commande vocale.
Patent CA-3028154-A1 (CA)
Title: Magnetic resonance volumetric imaging
Inventor: KAWRYKOW IWAN
IPC: G01R33/565
Filed: 2017-06-21
Abstract: Reference data relating to a portion of a patient anatomy during patient motion can be acquired from a magnetic resonance imaging system (MRI) to develop a patient motion library. During a time of interest, tracking data is acquired that can be related to the reference data. Partial volumetric data is acquired during the time of interest and at approximately the same time as the acquisition of the tracking data. A volumetric image of patient anatomy that represents a particular motion state can be constructed from the acquired partial volumetric data and acquired tracking data.
Patent CA-3029072-A1 (CA)
Inventor: VALAT CHRISTOPHE
IPC: F16K7/06
Filed: 2017-06-26
Abstract: The invention concerns a cassette (16) for cell culture comprising: - an at least partially rigid housing (90) internally defining an internal space inside which a cell culture bag (100) defining an internal volume is arranged and attached, - conduits (36, 38) each connected at one end to the internal volume of the bag (100) and each having a second end situated outside the housing (90), - valves (128, 130) for enabling/preventing the flow of fluid through the conduits (36, 38) that are mounted on the housing (90).
Patent CA-3031367-A1 (CA)
Inventor: FRANCK JAN
IPC: B41J25/34
Filed: 2017-07-31
Abstract: The invention is directed to a device (1) and to a method for aligning printheads (2) in relation to each other, each of the printheads being provided with a nozzle plate with multiple nozzles for printing, and with at least one round hole and/or at least one elongated hole in the nozzle plate for manufacturing and/or mounting purposes, comprising and using a mounting template for multiple printheads (2), wherein, for each printhead (2), at least one counterpart is provided, preferably in the form of pins that fit exactly into at least one round hole and/or at least one elongated hole in the corresponding nozzle plate, so that when the printheads (2) are inserted into the mounting template in such a way that the pairs of round hole counterparts and elongated hole counterparts engage the corresponding round holes and elongated holes in the nozzle plate, the nozzles of all printheads (2) are correctly aligned in relation to each other.
Patent CA-3039118-A1 (CA)
Inventor: DEEV ROMAN VADIMOVICH
IPC: A61P19/00
Filed: 2017-06-27
Abstract: The invention relates to medicine and veterinary science, and describes methods of producing optimized osteoplastic materials, characterized by a highly accurate dose of nucleic acids, more effective release dynamics of gene constructs from the structure of a carrier matrix, and an increased level of transfection of cells of the recipient bed by a biologically active substance. The first method relates to gene constructs, and enables same to be divided into two fractions which more effectively stimulate a repair process. The second method relates to functionalization of carrier matrices by complexing agents. Furthermore, a method is disclosed for producing sterile medical products from optimized gene-activated materials.