baber/WOPTO huggingface dataset:
Patent ZA-200006685-B (ZA)
Title: A hepatocyte targeting polyethylene Glyco-grafted poly-l-lysine polymeric gene carrier.
Inventor: PARK JONG SANG
IPC: A61K47/34
Filed: 2000-11-16
Abstract: A compound for targeted gene delivery is provided consisting of polyethylene glycol (PEG) grafted poly(L-lysine) (PLL) and a targeting moiety, wherein at least one free amino function of the PLL is substituted with the targeting moiety, and the grafted PLL contains at least 50% unsubstituted free amino function groups. TM is preferably lactose or galactose which are capable of specifically targeting a hepatoma cell or a liver cell. The new synthetic carriers with various substitution ratios of targeting moiety-PEG were characterized using NMR spectroscopy. The new polymeric gene carriers of this invention are capable of forming stable and soluble complexes with nucleic acids, which in turn are able to efficiently transform cells. PEG attached to the PLL gives better solubility properties to the gene/carrier complex and improved transfection efficiency without considerable cytotoxicity. Methods of preparing and using the targeting moiety-PEG-PLL as gene carriers to efficiently transfect cells are disclosed.
Patent ZA-200107963-B (ZA)
Title: Methods of treating leukemia.
Inventor: GOURDEAU HENRIETTE
IPC: A61K38/18
Filed: 2001-09-27
Abstract: The present invention provides a novel method for treating leukemia and more particularly acute myelogenous leukemia (AML) in a host comprising administering to the host a therapeutically effective amount of a compound having formula (I): wherein B is cytosine or 5-fluorocytosine and R is selected from the group comprising H, monophosphate, diphosphate, triphosphate, carbonyl substituted with a C 1 - 6  alkyl, C 2-6  alkenyl, C 2-6  alkynyl, C 6-10  aryl, and (a) wherein each Rc is independently selected from the group comprising H, C 1-6  alkyl, C 2-6  alkenyl, C 2-6  alkynyl and an hydroxy protecting group; and wherein said compound is substantially in the form of the (-) enantiomer.
Patent ZA-200109314-B (ZA)
Title: Rapid dehydration of proteins.
Inventor: MOORE BARRY DOUGLAS
IPC: A61K47/36
Filed: 2001-11-12
Abstract: The present invention relates to protein-coated micro-crystals and their method of preparation. The protein-coated micro-crystals may find particular application in preparing enzymes for use as biocatalysts; preparation of therapeutic proteins for use in pharmaceutical formulations; production of cleansing agents comprising enzymes; production of paints, varnishes, coatings, films and the like comprising proteins which impart protective and/or antifouling properties; production of films, polymers, inks, coatings, electrodes and/or optical materials comprising proteins for diagnostic kits and/or biosensor applications; use of proteins for studies of molecular recognition, molecular binding and inhibitor binding in non-aqueous media; and preparation of protein based food additives.
Patent ZA-200307400-B (ZA)
Title: Device and method for connecting a pressure source to a container.
Inventor: KLAAUW GUIDO PETRUS JOHANNES V
IPC: B67D1/04
Filed: 2003-09-23
Abstract: An assembly of a container and a connecting device for connecting the container to a pressure source, wherein the container is provided with a tapping rod having therein at least one valve for releasing an input and/or output opening of the container, wherein the connecting device is provided with a housing with a first coupling and the container is provided with a metal outer casing with a cylindrical neck, which neck is secured by a first end on the outer casing and adjacent the opposite second end is provided with an outwardly extending second flange, which defines a second coupling for cooperation with the first coupling, wherein the tapping rod has been secured in the neck and wherein the neck, between the flange and first end, is substantially smoothly finished on the outside, and has a diameter that is smaller than the maximum diameter of the flange, the arrangement being such that in coupled condition of the connecting device and the container the second coupling is at least supported against the underside of the flange proximal to the first end of the neck, and the tapping rod is locked in the neck by at least the connecting device.
Patent ZA-200308296-B (ZA)
Title: Spray boom for a hydraulic descaling facility.
Inventor: VOELKEL WERNER
IPC: B21B45/02
Filed: 2003-10-24
Abstract: In order to provide a spray boom with a plurality of spray nozzles for a hydraulic descaling facility with which a high temperature constancy from beginning to the end of the rolling stock is insured and a too rapid cooling of the surface is prevented, it is proposed, in accordance with the invention, to assign a check valve to each spray nozzle.
Patent ZA-200504122-B (ZA)
Title: Device at fixing means for fixation of bone fragments at bone fractures
Inventor: HENRIK HANSSON
IPC: A61B17/78
Filed: 2005-05-20
Abstract: The fixing device (1) comprises a pin (7) which can be inserted into a sleeve (5) in the length direction of the latter. The pin has a rear part and at least two front parts (9, 10), the latter having curved tips which can be driven out through holes (13, 14) in the front part of the sleeve. The front parts of the pin have a thickness which increases in the direction of the rear part of the pin, so that driving these front parts through the holes in the sleeve causes them to bend, their tips being bent backwards towards the pin central axis. Once the front parts have been driven out of the sleeve, sections of the latter in contact with the sleeve will have a relatively large thickness and will be stronger than the sections driven into the bone material (3).  The fixing device is preferably a nail.
Patent ZA-200510402-B (ZA)
Title: Apparatus for rectifing round pipe and tubing
Inventor: KASTROPIL ANTHONY
IPC: B21D/
Filed: 2005-12-22
Abstract: Apparatus for reducing the diameter, rounding or straightening of pipe or tubing by rolling comprising a plurality of cylindrical rollers arranged in a parallel-cylindrical array through which the pipe or tubing is passed, the rollers being skewed to displace their central contact zones radially inwards bringing them into forceful contact with the external surface of the pipe or tubing, and being rotated to cause the central contact zones to describe helical paths along the external surface of the pipe or tubing. Thereby to progressively apply locally to the whole of the external surface of the pipe or tubing a compressive force in excess of the yield strength of its material, causing the pipe or tubing to adopt a set at a smaller diameter.
Patent ZA-200704658-B (ZA)
Title: Spheroidal cast alloy and method for producing cast parts from said spheroidal cast alloy
Inventor: MENK WERNER
IPC: C22C/
Filed: 2007-06-22
Abstract: A spheriodal cast alloy for producing cast iron products with great mechanical strength, high-wear resistance and a high degree of ductility. The alloy comprises the following as non-iron components: between 2.5 and 2.8 wt. % C, between 2.4 and 3.4 wt. % Si, between 0.02 and 0.08 wt. % P, between 0.02 and 0.06 wt. % Mg, between 0.01 and 0.05 wt. % Cr, between 0.002 and 0.02 wt. % Al, between 0.0005 and 0.015 wt. % S, between 0.0002 and 0.002 wt. % B and conventional impurities. The alloy contains between 3.0 and 3.7 wt. % C, between 2.6 and 3.4 wt. % Si, between 0.02 and 0.05 wt. % P, between 0.025 and 0.045 wt. % Mg, between 0.01 and 0.03 wt. % Cr, between 0.003 and 0.017 wt. % Al, between 0.0005 and 0.012 wt. % S and between 0.0004 and 0.002 wt. % B. The alloy is used for example to produce chassis parts or brake discs in the automobile industry.
Patent ZA-200901273-B (ZA)
Title: Peptide deformylase as a tool for development of mycobacteria specific inhibitors
Inventor: SAXENA RAHUL
IPC: C12N15/113
Filed: 2007-07-27
Abstract: The present invention relates to the design of the Antisense-oligonucleotide complementary to the specific region of peptide deformylase gene from Mycobacterium tuberculosis. The use of this Antisense-oligonucleotide on mycobacterial culture inhibits the production of the peptide deformylase enzyme by hybridizing within the region, which is found to be responsible for maintaining stability as well as retaining the functionality of the enzyme and thus in turn affecting the growth of the cells. This invention also establishes the essentiality of the peptide deformylase enzyme in mycobacteria and claims it as a drug target in this microorganism.
Patent ZA-202100014-B (ZA)
Title: Adaptive control point selection for affine motion model based video coding
Inventor: HE YUWEN
Filed: 2021-01-04
Abstract: Systems, methods, and instrumentalities are disclosed for motion vector clipping when affine motion mode is enabled for a video block. A video coding device may determine that an affine mode for a video block is enabled. The video coding device may determine a plurality of control point affine motion vectors associated with the video block. The video coding device may store the plurality of clipped control point affine motion vectors for motion vector prediction of a neighboring control point affine motion vector. The video coding device may derive a sub-block motion vector associated with a sub-block of the video block, clip the derived sub-block motion vector, and store it for spatial motion vector prediction or temporal motion vector prediction. For example, the video coding device may clip the derived sub-block motion vector based on a motion field range that may be based on a bit depth value.
Patent ZA-202204149-B (ZA)
Title: Cap for a container
Inventor: ZENO ZUFFA
Filed: 2022-04-12
Abstract: A cap (1) for a container comprises: a body (2), configured to be coupled and uncoupled relative to the neck of the container and including a side wall (21), which extends around a longitudinal axis (A), and a transverse wall (22); a tamper evident ring (3), configured to remain anchored to the neck of the container even when the body (2) is uncoupled from the neck and including a joining portion (32) where the tamper evident ring (3) is joined to the body (2), the joining portion (32) being configured to be torn along a full perimeter surrounding the longitudinal axis (A), wherein the cap (1) comprises a connecting band (4) having a first end (41) connected to the side wall (21) of the body (2) and a second end (42) connected to the retaining portion (31) of the tamper evident ring (3).
Patent ZA-202305676-B (ZA)
Title: Method for separating and purifying glucocorticoids in urine by online two-dimensional semi-preparative liquid chromatography
Inventor: LIU BING
Filed: 2023-05-26
Abstract: The invention discloses a method for separating and purifying glucocorticoids in urine by online two-dimensional semi-preparative liquid chromatography. The method for separating and purifying glucocorticoids in urine by online two-dimensional semi-preparative liquid chromatography comprises that follow steps: separating and purifying glucocorticoid by an online two-dimensional central cut mode chromatographic separation system, pre-separating crude urine sample by a one-dimensional liquid chromatographic column, then switching valve components, switching the component to a two-dimensional chromatographic column for further fine separation, loading the obtained target component into a GC-MS system, measuring the corresponding GC-MS ion flow diagram and mass spectrum diagram, and confirming its structure. The method for online two-dimensional separation of glucocorticoids provided by the invention optimizes the previous off-line two-time separation mode, greatly simplifies the pretreatment steps, saves the cost and improves the detection sensitivity.
Patent ZA-202305873-B (ZA)
Title: Resource scheduling method and system for satellite elastic internet, computer device, and medium
Inventor: LUO ZHIYONG
Filed: 2023-06-01
Abstract: The present disclosure provides a resource scheduling method and system for a satellite elastic Internet, a computer device, and a medium. A delay-sensitive satellite elastic Internet architecture is established based on a many-to-many mode between a low earth orbit (LEO) satellite and a client; after a satellite elastic Internet resource scheduling model is established based on the delay-sensitive satellite elastic Internet architecture, a minimum delay optimization model is established based on the satellite elastic Internet resource scheduling model, and the minimum delay optimization model is converted into a corresponding Markov decision model; and the Markov decision model is solved to obtain a resource scheduling strategy. This method can fully utilize computing and storage resources of a satellite, avoid affecting queuing delay performance, meet diverse needs of a client, improve QoS, and improve, based on a deep reinforcement learning (DRL) algorithm, computation efficiency of resource scheduling, thereby achieving service-prioritized, low-delay and load-balanced resource scheduling. This method has a strong generalization capability and high practical value.
Patent MX-336803-B (MX)
Title: Intermediate film for laminated glass and laminated glass.
Inventor: NAKAMURA KOZO
IPC: C03C27/12
Filed: 2009-04-23
Abstract: Provided is an intermediate film for laminated glass which exerts excellent vibration-damping properties at high temperature and excellent sound insulation properties over a wide temperature range. An intermediate film for laminated glass, comprising horizontally arranged portions (A) and (B) which consist respectively of a resin composition (A) or a resin (A) and a resin composition (B) or a resin (B), wherein the difference between Ta and Tb is 10Â°C or above (wherein Ta is a temperature at which the loss tangent of dynamic viscoelasticity of the resin composition (A) or the resin (A) at a frequency of 1Hz is maximum and Tb is a temperature at which the loss tangent of dynamic viscoelasticity of the resin composition (B) or the resin (B) at a frequency of 1Hz is maximum).
Patent MX-344383-B (MX)
Title: Rubber granulate conversion process for producing a semi-active carbonized substance and a plasticizer.
Inventor: STANISLAW BUDZYN
IPC: B82Y30/00
Filed: 2010-06-01
Abstract: The present invention relates to a rubber granulate conversion process comprising steps consisting in: a) pyrolysing the rubber granulates at a temperature between 400 and 500Â°C in the presence of water, to obtain a carbonized substance and a gaseous phase; and b) recovering the carbonized substance obtained during the previous step. The invention also relates to the products resulting from the conversion process and to the use of said products.
Patent MX-343798-B (MX)
Title: Equipment for classifying coconut water.
Inventor: FEDERICO FELIX HAHN SCHLAM
IPC: G01N27/404
Filed: 2013-01-23
Abstract: The invention refers to equipment for classifying coconut water, which is characterized in that it comprises a means for receiving the coconut water and a measurement section with an OD and pH sensor, which includes, at the end portion thereof, a means for regulating the flow that would limit said flow during the measurement and allow a larger volume to pass by gravity once the measurement has been performed; the sensors are connected to a central unit for controlling and processing the measured variables, including an electronic circuit with a microprocessor having a control algorithm, which also controls the different means for regulating the flow of coconut water; a second means for receiving the coconut water may receive the water with the measured CO and pH control variables, this means including at the bottom portion thereof, four means for regulating the flow and discharge of coconut water, these means being arranged in a predetermined manner and separated apart one from the ot her, also being actuated and controlled by the central processing and control unit, where each means is destined for each quality type of coconut water (very tender, tender, hardly mature and mature).
Patent MX-354877-B (MX)
Title: Secondary packaging comprising multiple primary packaging sizes.
Inventor: KLAUS HARTWIG
IPC: B65D21/02
Filed: 2011-12-07
Abstract: The invention relates to a composite package (8) linked together into a single unit, and comprising a plurality of individual containers (1, 2, and 3) of varying shapes and/or volumes and being assembled according to different orientations in the composite package. In the composite package are defined strong and weak containers according to their mechanical resistances on which apply external loads. According to the invention, the strong containers are arranged in their orientation along the direction(s) of external loads placed upon the composite package thereby protecting the weakest ones.
Patent MX-341765-B (MX)
Title: Abrasion-resistant steel sheet exhibiting excellent resistance to stress corrosion cracking, and method for producing same.
Inventor: KEIJI UEDA
IPC: C22C38/32
Filed: 2012-03-28
Abstract: Provided are an abrasion-resistant steel sheet suitable for use in construction machinery and industrial machinery and exhibiting excellent resistance to stress corrosion cracking, and a method for producing said steel sheet. Specifically, a steel sheet having a composition which contains, in mass%: 0.20 to 0.30% C, 0.05 to 1.0% Si, 0.40 to 1.20% Mn, 0.1% or less P, S and Al, 0.01% or less N, 0.0003 to 0.0030% B; one or more selected from among Cr, Mo and W; and one or more selected from Nb, Ti, Cu, Ni, V, REM, Ca, and Mg as necessary; the remainder being Fe and unavoidable impurities. The aforementioned composition also has a DI* of 45 or more from the contained components. Additionally, the steel sheet has a microstructure having tempered martensite as the base phase, and 2Ã—106/mm2 of cementite having a diameter of 0.05 Âµm or less in terms of equivalent circular diameter. Moreover, steel billets having the aforementioned composition are hot rolled after being heated. Subsequently, the steel billets are reheated after being air cooled and are rapidly cooled. Then the steel billets are hot rolled and are rapidly cooled immediately thereafter.
Patent MX-349860-B (MX)
Title: Method of dissolving and/or inhibiting the deposition of scale on a surface of a system.
Inventor: KENNETH L ZACK
IPC: C02F1/68
Filed: 2012-04-13
Abstract: A method of dissolving and/or inhibiting the deposition of scale on a surface of a system comprises the step of bringing the surface of the system into contact with a composition. The composition can comprise from about 3 to about 15 parts by weight of a chelating component. The chelating component is selected from the group of MGDA, NTA, HEDTA, GLDA, EDTA, DTPA, and mixtures thereof. The composition can further comprise from about 3 to about 15 parts by weight of an acidic component, which is different than the chelating component. The composition can further comprise at least about 60 parts by weight of water. Each of the parts by weight ranges above are based on 100 parts by weight of the composition. The composition may further comprise a surfactant component and/or a corrosion inhibitor.
Patent MX-345698-B (MX)
Title: Proppant mixing and metering system.
Inventor: HAU NGUYEN-PHUC PHAM
IPC: G01F11/00
Filed: 2012-05-25
Abstract: An oilfield material reservoir is disclosed. The oilfield material reservoir has a body, the body having an upper end, a lower end, a sidewall extending between the upper and lower ends, the sidewall defining a recess within the body, an opening defined by the upper end, and a first orifice defined by the lower end. The oilfield material reservoir is also provided with a metering gate connected to the body at the lower end. The metering gate has a base having a second orifice aligned with the first orifice, and a knife gate connected to the base. The second orifice has a substantially trapezoidal shape. The knife gate is configured to slidably cover the second orifice. A method is also disclosed for controlling a discharge rate of oilfield material within the oilfield material reservoir by adjusting a metering open area of the second orifice according to mathematical modeling equations.
Patent MX-351034-B (MX)
Title: Wettable, non-leachable peat moss, method of preparation, and method of use.
Inventor: JEAN-CHRISTOPHE CASTAING
IPC: C08L5/08
Filed: 2012-08-06
Abstract: A peat moss composition having improved water holding capacity, hydrophilicity, and/or anti-leaching properties comprising one or more polysaccharides, for example guars and/or guar derivatives, is disclosed. A method of preparing the peat moss composition and a method of using it are also disclosed.
Patent MX-363235-B (MX)
Title: Movement joint.
Inventor: ANDREW KEEN
IPC: E01C11/14
Filed: 2012-08-31
Abstract: A free movement, arris protection, construction joint (1) has a pair of arris protection members (2,3) formed complementarily from strips of sheet with a continuous trapezium wave form. A divider one (2) of the members is typically 100mm deep for a nominal 0.1m deep slab. The other one (3) is typically 50mm deep. The members are of steel plate. The wave form is comprised of flanges (4,5) extending in the length of the joint and of webs (6) angled to the flanges and the length of the joint. The flanges (4,5) are spaced on opposite sides of a mid-plane (7) of the joint. The members (2,3) are bolted together with flangible nylon bolts (8), with their top (in use) edges flush. Welded to the outer ones of the flanges are L strips (9) having apertures (10) in their flats (11) extending from the flanges for anchoring the joint to its slabs. Beneath the anchor members, extending out from every other flat (5) of the deep divider one (2) of the protection members are load transfer dowels (14), with sleeves (15) on their extent across the mid-plane and beyond. In use, concrete is cast with a horizontally castellated edge, castellations at positions (16) being bounded by the divider member (2). Complementary castellations on the other side of the joint at the positions (17) interdigitate with the first castellations (16). The castellations extend to the full depth of the slabs and can be expected to have a long life.
Patent MX-338985-B (MX)
Title: Sacrificial adhesive coatings.
Inventor: SALAMONE JOSEPH C
IPC: C09D183/04
Filed: 2012-09-19
Abstract: Combinations of solubilized, covalently crosslinked, siloxy-containing polymers in a solvent system of a volatile hydrophobic (non-polar) liquid that is non-stinging to a user are excellent non-irritating liquid coating materials for forming films, which, after solvent evaporation, are water insoluble but water-vapor permeable and lightly adherent to surfaces such as skin and mucous membranes. The crosslinking content is greater than 1 weight % and can be as much as 16 weight %. In comparison to non-crosslinked polysiloxy films, or crosslinked films of 1 weight % or less, the enhanced crosslinked polysiloxy films, while continuing to be soluble in the solvent, have reduced tack and reduced adhesion to skin and can act as sacrificial coatings under strongly adherent pressure sensitive adhesives.
Patent MX-350715-B (MX)
Title: Apparatus and method for processing a concrete tower segment of a wind turbine.
Inventor: GUENTHER HORN
IPC: B23Q17/24
Filed: 2012-11-21
Abstract: The invention relates to a processing apparatus for processing an upper segment edge (8) of a tower segment of a concrete tower (102) in order to prepare the tower segment for the attachment of at least one further tower segment. According to the invention, it is proposed that the processing apparatus comprises a processing means (10) for processing the segment edge (8) and a supporting apparatus (32, 34) which is to be fastened in the region of the segment edge (8) and is intended for displaceably supporting and guiding the processing means (10) along the segment edge (8).
Patent MX-354741-B (MX)
Title: Thymol and totarol antibacterial composition.
Inventor: REGINA HOURIGAN
IPC: A61P31/04
Filed: 2011-12-15
Abstract: An antibacterial composition comprising thymol and totarol. This combination provides synergistic effect against gram negative and gram positive bacteria.