baber/WOPTO huggingface dataset:
Patent RU-2768186-C2 (RU)
Title: Combined drugs containing pkm2 and hmgb1 modulators
Inventor: GDYNYA Georg
IPC: A61P35/00
Filed: 2016-12-12
Granted: 2022-03-23
Abstract: FIELD: medicine. 
     SUBSTANCE: group of inventions relates to a combined drug for the treatment of undesirable cell proliferation, containing a pyruvate kinase M2 (PKM2) activity modulator and an agent providing a highly mobile group polypeptide box 1 (HMGB1) or a derivative thereof. Group of inventions also relates to a kit for treating undesirable cell proliferation, comprising a PKM2 activity modulator and an agent providing HMGB1 or a derivative thereof; oligophosphorylated polypeptide HMGB1 or its derivative for treatment of undesirable cell proliferation, in which at least one of the tyrosine residues corresponding to amino acids Y109, Y144, Y155 and Y162 of the HMGB1 polypeptide is replaced with a non-phosphorylated amino acid. 
     EFFECT: group of inventions provides treating undesirable cell proliferation. 
     20 cl, 8 ex, 3 tbl, 8 dwg
Patent RU-2716040-C2 (RU)
Title: METHOD FOR CONSTRUCTING HIGH-PERFORMANCE FAULT-TOLERANT DATA STORAGE SYSTEMS BASED ON DISTRIBUTED FILE SYSTEMS AND NVMe OVER FABRICS
Inventor: DRUZHININ EGOR ALEKSANDROVICH
IPC: G06F17/40
Filed: 2018-06-22
Granted: 2020-03-05
Abstract: FIELD: physics.SUBSTANCE: invention relates to data storage systems. Method of constructing high-performance fail-safe storage systems based on distributed file systems, which determines a method of distributing NVMe disks and OSS of a file system over a group of servers to achieve redundancy and fault tolerance. Common local network is used both for accessing file system data, and for accessing NVMe over Fabrics disks, without dedicated SAN.EFFECT: technical result is wider range of means.1 cl, 6 dwg
Patent RU-2734343-C2 (RU)
Title: Spring-loaded latch for locks
Inventor: ALBAN GIACOMO MARIO
IPC: E05B15/16
Filed: 2017-01-11
Granted: 2020-10-15
Abstract: FIELD: locks. 
     SUBSTANCE: spring-loaded latch (10) for locks, comprising metal part (11) and at least one part (12) made of plastic material. Metal part (11) forms central part of spring-loaded latch. There are two parts (12, 13), made of plastic material—upper part (12) and lower part (13) relative to operating configuration. Upper part (12) and lower part (13) project outside by corresponding outer surfaces (14, 15, 16, 17, 18, 19) relative to corresponding outer surfaces (20, 21, 22, 23) of central metal part (11). 
     EFFECT: spring-loaded latch for locks is proposed. 
     1 cl, 9 dwg
Patent RU-2723445-C2 (RU)
Title: Digital phase detector
Inventor: CHERNOYAROV OLEG VYACHESLAVOVICH
IPC: H04L27/22
Filed: 2018-10-01
Granted: 2020-06-11
Abstract: FIELD: radio equipment. 
     SUBSTANCE: invention can be used in devices for receiving analogue information signals with phase modulation and for separation (measurement) of phase shift, received and reference signals in systems of phase synchronization. Technical result is achieved by the fact that digital phase detector containing analogue-to-digital converter, multi-bit codes shift register by four counts, first and second n-cascade channels of quadrature signal processing and clock pulse generator (CPG), additionally comprises a normalizing device, a digital arctangent former and a phase correction unit, at output of which binary code of phase shift of received signal is generated relative to CPG pulses. 
     EFFECT: providing high-speed digital phase detection of a received signal with high noise immunity and eliminating non-identity of quadrature signal processing channels. 
     1 cl, 6 dwg
Patent RU-2754507-C2 (RU)
Inventor: KUTOK JEFFERY L
IPC: A61K31/52
Filed: 2017-06-23
Granted: 2021-09-02
Abstract: Настоящая группа изобретений относится к медицине, а именно к онкологии, и касается комбинированного лечения лимфомы. Для этого вводят ингибитор фосфатидилинозитол 3-киназы дувесилиб в комбинации с ингибитором XP01 селинексором или в комбинации с ингибитором контрольных точек PD-1. Это обеспечивает эффективное лечение лимфомы за счет синергетического противоопухолевого действия компонентов комбинации. 2 н. и 33 з.п. ф-лы, 2 пр., 1 табл., 1 ил.
Patent RU-2739403-C2 (RU)
Inventor: LI YONGQIAN
IPC: C21B3/08
Filed: 2017-03-17
Granted: 2020-12-23
Abstract: FIELD: metallurgy. 
     SUBSTANCE: group of inventions relates to a method for steel processing of steel-smelting slag and device for its implementation. Method for steel making slag processing includes the stages, at which: slag tank (2) containing melted steel-smelting slag (3), is changed into feed position and is inclined by means of inclination mechanism (1) of slag vessel (2), which ensures retention of slag vessel (2), for overflow of fluid flow slag (3) through loading chute (51) into rotary roller device (5) for its treatment by roller device (5); remaining in slag tank (2) high-viscous sticky slag is directed into roller device (5) using slag removal device (4); slag tank (2) is tilted by at least 150° or overturned by means of inclination mechanism (1) of slag tank (2) to guide bottom slag at bottom of slag container (2) to roller device (5). 
     EFFECT: processing metal-containing slag in full volume, in which treatment of whole slag mass is achieved by means of one roller device, capable of treating both liquid metal-containing slag having good fluidity and solid bottom slag free from fluidity. 
     7 cl, 1 tbl, 2 ex, 15 dwg
Patent RU-2741137-C2 (RU)
Title: Система управления поставками жидкостей в закрытой таре
Inventor: Vinogradov Andrej Albertovich
IPC: B67D3/00
Filed: 2019-03-07
Granted: 2021-01-22
Abstract: Изобретение относится к области управления поставками, а именно поставками жидкостей в закрытой таре, в том числе питьевой воды в бутылях, напитков в закрытой металлической таре, горюче-смазочных материалов, которые поставляются в больших бочках на станции технического обслуживания, и может быть использовано службами снабжения. Технический результат, на получение которого направлено изобретение, заключается в обеспечении возможности использования стандартных емкостей с жидкостями, в том числе в металлической таре, а также возможности учета в системе информации о наличии и заполненности мест для хранения заполненных и пустых емкостей. Технический результат достигается в системе управления поставками жидкостей в закрытой таре, в том числе в металлической таре, содержащей сервер с установленным программным обеспечением для хранения и обработки информации, по крайней мере, одну подставку у потребителя под емкость или устройство с установленной в нем емкостью (например, водный диспенсер с установленной бутылью), выполненную, по крайней мере, с одним датчиком массы, выполненным с возможностью измерения массы емкости жидкости или устройства с установленной в нем емкостью, с устройством ввода информации, выполненным с возможностью ввода потребителем информации о наличии и заполненности мест для хранения заполненных и пустых емкостей у потребителя, а также с модемом, выполненным с возможностью передачи на сервер информации об изменении массы емкости с жидкостью и о наличии и заполненности мест для хранения заполненных и пустых емкостей у потребителя, по крайней мере, одно рабочее место поставщика с установленным программным обеспечением, выполненным с возможностью доступа к серверу, с возможностью учета в системе информации о наличии и заполненности мест для хранения заполненных и пустых емкостей, с возможностью прогнозирования расхода жидкостей и составления плана по снабжению потребителей емкостями с жидкостью и плана по закупке поставщиком необходимого количества таких емкостей. 7 з.п. ф-лы, 3 ил.
Patent UA-61981-C2 (UA)
Title: A composition of the ink for marking pens
Inventor: ANDROPOV VOLODYMYR IVANOVYCH
IPC: C09D11/16
Filed: 2000-06-27
Abstract: The invention allows enhancing the water-resistance of inks on unbuckling supporting materials: glass, metal, wood. The composition contains: 86-88 % by weight of mixture of ethyl and isopropyl alcohols at a ratio of 1:1, 2 % by weight of ethylene- or diethylene glycol, 8-10 % by weight of alcohol-soluble dye-stuff, 2 % by weight of film-forming substance û cyclohexanon formaldehyde oligomer.
Patent UA-72015-C2 (UA)
Title: Method and device for hot rolling of a thin strip
Inventor: STECH VOLODYMYR STANISLAVOVYCH
IPC: B21B1/34
Filed: 2002-06-25
Abstract: The invention relates to the method of hot rolling of thin strip on the mills containing roughing reverse stand and finishing rolling group with furnace coilers. A method for hot rolling of thin strip consists in reverse roughing rolling of the slab in the roughing stand up to the intermediate thickness, transfer of the strip of intermediate thickness into the finishing group consisting of one or more rolling stands, reverse finishing rolling of the strip in the finishing rolling group up to the final thickness with winding û unwinding of the strip of intermediate thickness on the coilers in the furnaces mounted upstream and downstream the finishing rolling group. Besides, the reverse rolling of slab in the roughing stand is performed in parallel with the reverse rolling in the finishing rolling group obtained from the previous slab, and the strip in at least one unpaired roughing cut, except for the last unpaired pass, are passed without turning through the rolling device, during the last roughing pass the strip is rolled up in the intermediate roll in the rolling device followed by the unrolling for transfer of the strip into the finishing rolling group, in this case the completion of the cycle of the finishing rolling of the previous strip is performed simultaneously with the transfer of the next strip into the finishing rolling group. The mill for production of thin hot-rolled strip includes heating furnace, transport and working rollers, roughing reverse stand, finishing rolling group consisting of one or more rolling stands, coilers in the furnaces mounted upstream and downstream the finishing rolling group, shears with draw rolls, coiler for winding of finished strip into the roll. The mill is equipped with rolling device, the distance with this device and roughing stand is selected in such a manner that it shall not exceed the length of semi-finished rolled product in the next to last unpaired roughing pass and is regulated by the mathematical dependence. The invention ensures favorable temperature parameters and reduces the length of the processing line of the mill.
Patent UA-73339-C2 (UA)
Title: Substituted oxazolidinones and use thereof for the prevention of blood coagulation
IPC: A61K31/427
Filed: 2000-12-11
Abstract: The invention relates to the field of blood coagulation, more specifically it relates to novel oxazolidinone derivatives of the general formula (I), to methods for producing them as well as to their use as active substances for medicaments for the prophylaxis and/or the treatment of diseases. (I)
Patent UA-83804-C2 (UA)
Title: Method and unit for fluidifying powder product on fat basis, in particular in producing chocolate and similar products
Inventor: PARSONS NICHOLAS TYERS
IPC: A23G1/10
Filed: 2003-06-10
Abstract: The invention relates to a method for lowering the viscosity of a fat based mixture comprising solids and fat that have been previously refined 10 a powdery mass characterized in that the powdery mass is submitted to elongational flow effective as such to provide-breaking up of the agglomerates and intimate interactions of the solids with the fat thereby resulting in the production of a pasty mass with coating of the solids with the fat. The method enables to replace conching in a traditional conche or at least reduce conching time or increase the subsequent loading and throughput of the fat based mass in traditional conches.
Patent UA-80340-C2 (UA)
Title: Device for sowing seed and fertilizers in holes
Inventor: BILOKON OLEKSANDR PETROVYCH
IPC: A01B29/00
Filed: 2005-12-05
Abstract: A device for sowing seed and fertilizers in holes contains a frame with supporting-driving wheels, a hopper for seed and fertilizers with a dozer, fertilizer and seed tubes, a scraper bar, a coverer and a roller. On the frame in front of the scraper bar an arrow-shaped furrow opener, fertilizer and seed tubes are equipped with a collector with sliding gate having back kinematic coupling with the scraper bar which is made in the form of a slide with a set of replaceable cutting elements. A crank shaft of the supporting-driving wheels is connected by mechanical transmission to the slide and the sliding gate of the collector which due to own reciprocal movement in the opposite-inverted directions have the possibility to form hole beds and to guide therein sowing material from the collector on the device moving on the field.
Patent UA-88282-C2 (UA)
Title: housing of angle drive for steering control
Inventor: BAKHMACH YEVHENII STEPANOVYCH
IPC: B62D1/00
Filed: 2006-05-15
Abstract: A housing of angle drive for steering control contains a basis with openings for fastening. The basis is made in the form of two parts of V-shaped form, which apexes are directed to the opposite sides. The openings located near the ends of the rays are blind threaded, while the openings located near the apexes are through.
Patent UA-92721-C2 (UA)
Title: Enriched antibody population, highly specific for an antigen of a surface polysaccharide lipoarabinomannan (lam) from a mycobacterium, method for detecting mycobacterial infection in a sample and a kit for detecting a mycobacterial infection
Inventor: KOULCHIN VLADIMIR A
IPC: G01N33/537
Filed: 2005-07-20
Abstract: The invention relates to an enriched antibody population, highly specific for an antigen of a surface polysaccharide lipoarabinomannan (LAM) from a mycobacterium. In a related embodiment, the antibody is enriched by having been raised in an environment that maintains antigenically active antigen. These antibodies may be used in an immunoreactive environment for detecting the presence of a mycobacterial infection in a sample from a subject.
Patent UA-91030-C2 (UA)
Title: Clay purification method
Inventor: DENISE FAYOLLE
IPC: A61K33/00
Filed: 2005-09-16
Abstract: The invention relates to a method for the purification of a clay that is intended for therapeutic use.
Patent UA-90315-C2 (UA)
Title: Interval control processor
Inventor: MANZHOS YURII SEMENOVYCH
IPC: G06F7/00
Filed: 2007-12-19
Abstract: The interval control-processor relates to computer facilities and can be used in designing data processing control means in increased reliability information and control systems, in designing built-in fell-safe systems, exercisers, verification etc. The device has a general-duty register bank, a temporary register unit, a communication register unit, an interval data register bank, a temporary interval search register bank, an arithmetic logic unit, a minimumal boundary substractor-adder, a maximum boundary substractor-adder, a divider-multiplier unit, a run-time module control unit, an instruction sequence unit, a bus control unit, a command decoder, a flag register, a minimal boundary register, a maximum boundary register, a primary-operand boundary multiplexer, a second-operand boundary multiplexer, the first minimal boundary multiplexer, the second minimal boundary multiplexer, the first maximum boundary multiplexer, the second maximum boundary multiplexer, an address adder, the first, second, third, fourth and fifth OR elements, the first and second AND elements, the first and second NOT elements, the first and second data buses, a front-side bus. Technical result: computational process control managememnt, failure-disturbance on-line detection and harware and software faults as well as increase of functioning reliability by means of definition of absence of interval program defects.
Patent UA-91739-C2 (UA)
Title: Device for luminescent tube armatures
Inventor: DUNGSKOG TAGE
IPC: F21Y115/10
Filed: 2007-02-08
Abstract: The present invention relates to a device for fluorescent tube armatures, the device being intended to replace a previously occurring fluorescent tube. The device has a light-emitting diode unit (4) comprising at least one electrical drive unit (4.1), which is connected to at least one phase wire, as well as is connected to at least one neutral wire via at least one wire (4.2) comprising at least one light-emitting diode (4.3).
Patent UA-101597-C2 (UA)
Title: Pseudoinfectious flavivirus and its using
Inventor: FROLOV LLLIA
IPC: C12Q1/70
Filed: 2007-02-27
Abstract: The invention relates to replicative defective pseudoinfectious virus where the genome of the mentioned virus comprises deletion in nucleotide sequence coding core (C) protein, and this deletion codes amino acids 26-100 of the mentioned C-protein or amino acid combination 26-100 of the mentioned C protein, and this deletion does not interrupt RNA-sequence, necessary for genome cyclization, or signal sequence for prM protein, necessary for appropriate prM/M maturation. The invention also relates to the process for production of such viruses in large scale, and using of such pseudoinfectious viruses in pharmaceutical composition for prevention of diseases caused by human or animals infesting with viruses of this family.
Patent UA-98499-C2 (UA)
Title: Dms in foaming creams
Inventor: NEUBOURG THOMAS
IPC: A61K9/12
Filed: 2008-06-19
Abstract: The invention relates to a foam formulation comprising an emulsion, comprising an oil phase and a water phase, the oil phase comprising at least one membrane-forming substance forming a lamellar membrane in the foam formulation.
Patent UA-101812-C2 (UA)
Title: Silicone gel-based compositions for wound healing and scar reduction
Inventor: PALEFSKY IRWIN
IPC: A61L15/60
Filed: 2008-09-30
Abstract: This invention is a composition comprising a cyclic siloxane, a silicone occlusive fluid, a silicone occlusive gel, and a silicone resin powder. The composition is useful for wound healing.
Patent UA-97571-C2 (UA)
Title: Apparatus and method for moulding part of packaging container
Inventor: ANDERSSON PAR
IPC: B29C45/08
Filed: 2008-11-26
Abstract: The present invention relates to an apparatus and a method for moulding one or more thermoplastic package parts in association each to an end portion (20) of a packaging container body (12). The apparatus is of the type which includes an inner mould element (24) and an outer mould element (26) between which a mould cavity (30) per package part is formed. At least one of these mould elements is at least partly freely suspended. In the case when one package part is moulded with the mould elements, the apparatus is characterized in that a plastic melt (32) is injected in a first number ≥1 of points (42) in the cavity (30), an island (45) of plastic melt for each point being formed inside the cavity, and that the distribution of said points (42) is such that a force centre (F) may be caused to pass through a surface (92) which is defined by a parallel projection (45', 45') of each one of said first number of islands (45) on a plane (P) which is orthogonal to a direction (D) of the compression force and, when said first number > second number of imaginary straight lines (90) which interconnect a third number of the parallel projections (45', 45') in such a manner that the surface (92) will be at its maximum.
Patent UA-95746-C2 (UA)
Title: Method for determination of level of maximum nuclear pollution of ichthyofauna of fresh water reservoirs
Inventor: KAHLIAN OLEKSANDR YEVHENIIOVYCH
IPC: G01T1/169
Filed: 2010-09-22
Abstract: The invention relates to biology-ecology, in particular to methods for determination of nuclear pollution of fresh-water ichthyofauna. The method prescribes determination of level of maximal radio-nuclide pollution of ichthyofauna of fresh water reservoirs with radio-chemical and/or gamma-spectrometric method, at that as type-indicator for determination of level of pollution of ichthyofauna of water reservoirs with 90Sr by specific activity of the radio-nuclide one uses the rudd, Scardinius erythrophthalmus L., and as type-indicator for determination of level of pollution of ichthyofauna with 137Cs – the perch Perca fluviatilis. For realization of the method one uses samples of the fish-indicator for the rudd – with dimensions 19-22cm, age 5-9 years and weight 130-260g, and for perch – with dimensions 23-30cm, age 5-9 years and weight 200-900g.
Patent UA-99396-C2 (UA)
Title: Commercial energy park and method for operation thereof
Inventor: DZENZERSKYI VIKTOR OLEKSANDROVYCH
IPC: H02J3/00
Filed: 2011-06-20
Abstract: A commercial energy park is used in energy production, mainly in energy supply of industry complexes connected to an integrated energy system related to a system operating with renewable energy sources. A united autonomous power system is supplemented with an external energy supply from mains and includes as a unit of differential control a load-center substation, a park of renewable energy sources integrated to a structure of consumer enterprises and looped by an individual accumulating block provided by equipment for transformation and supplying energy to consumers, as well as an assembly of accumulator batteries of large capacity, kinetic and heat storages, a distributed module integrated to storage and consumer systems, which comprises heat-exchangers for exhaust heat; an energy converter is made as a centralized boiler-room and provided for a hydraulic network for heat transportation via a heat agent from solar collectors, from systems of heat exchangers-utilizers, grouped in accordance with heat exhaust from working mechanisms, electric equipment, chemical reactors and heat pumps. Moreover, the renewable energy sources system supplies energy only for industry and office needs of local sectors of the industry complex that allows one to reduce consuming external energy and increase effectiveness of utilizing generated energy and to optimize energy distribution over the commercial energy park. The proposed engineering decision of formation of united energy system connected to the centralized network and combined with the system of renewable energy sources fully integrated in the commercial complex with high energy ratio provides for high stability of energy supply.
Patent UA-120828-C2 (UA)
Title: Nematocidal sulfonamides
Inventor: LAHM GEORGE P
Filed: 2010-05-04
Abstract: Disclosed are compounds of Formula 1 (see "Formula 1"), N-oxides, and salts thereof, wherein Z is О or S; and R1, R2, R3, Q and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling a parasitic nematode comprising contacting the parasitic nematode or its environment with a biologically effective amount of a compound or a composition of the invention.
Patent UA-106115-C2 (UA)
Title: 15-valent pneumococcal polysaccharide-protein conjugate vaccine composition
IPC: A61K39/00
Filed: 2011-02-03
Abstract: The present invention provides a multivalent immunogenic composition having 15 distinct polysaccharide-protein conjugates. Each conjugate consists of a capsular polysaccharide prepared from a different serotype of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F or 33F) conjugated to a carrier protein, preferably CRM197. The immunogenic composition, preferably formulated as a vaccine on an aluminum-based adjuvant, provides broad coverage against pneumococcal disease, particularly in infants and young children.
Patent UA-112058-C2 (UA)
Title: Спосіб виробництва металевої чашки з листового металу і прес для його здійснення
IPC: B21D51/26
Filed: 2011-04-13
Abstract: Запропоновані спосіб і пристрій, придатний для використання при виробництві двоскладових металевих ємностей. Зокрема, описаний прес, який виробляє чашкові секції з листового металу, поєднуючи при цьому операції витягування і обтягування. У результаті чашки, що сходять з преса переважно мають витончену товщину основи в порівнянні із вхідною товщиною листового металу.