baber/WOPTO huggingface dataset:
Patent CA-2414331-A1 (CA)
Inventor: CHERNOVA IRENE
IPC: A61K48/00
Filed: 2001-06-28
Abstract: L'invention concerne des molécules d'acides nucléiques isolées appelées molécules d'acides nucléiques PD-L2, codant de nouvelles molécules associées à B7, ces dernières molécules étant des ligands de PD-1. L'invention concerne également des molécules d'acides nucléiques antisens, des vecteurs d'expression de recombinaison contenant des molécules d'acides nucléiques PD-L2, des cellules hôtes dans lesquelles les vecteurs d'expression ont été introduits, ainsi que des animaux transgéniques non-humains dans lesquels une gène PD-L2 à été introduit ou interrompu. L'invention concerne également des polypeptides PD-L2 isolés, des protéines de fusion, des peptides antigènes, et des anticorps anti-PD-L2. L'invention concerne également des procédés destinés à favoriser ou inhiber l'interaction entre PD-L2 et PD-1. L'invention concerne également des procédés de diagnostic et de traitement faisant intervenir des compositions selon l'invention.
Patent CA-2415489-A1 (CA)
Title: Antistatic composition
Inventor: POWERS MICHAEL D
IPC: D06M13/148
Filed: 2001-07-11
Abstract: An antistatic composition that contains an antistatic agent and a humectant is provided. The antistatic agent, for example, can be an organic phosphate salt or an inorganic salt. Moreover, examples of suitable humectants are glycerin, propylene glycol, and the like. The humectant is present in an amount such that its resulting add-on level is less than about 0.05 wt.% when applied to a fabric. By utilizing such levels of the humectant, the resulting fabric can possess improved conductive properties, while also retaining water repellancy properties.
Patent CA-2416810-A1 (CA)
Title: Pharmacokinetic tool and method for predicting metabolism of a compound in a mammal
Inventor: DOERR-STEVENS JULIE
IPC: G06F19/00
Filed: 2001-07-30
Abstract: A system for simulating metabolism of a compound in a mammal is disclosed that includes a metabolism simulation model of a mammalian liver. This model has equations which when executed on a computer, calculate the rate of metabolism of the compound in the cells of the mammalian liver and a rate of transport of the compound into the cells, wherein the simulation model determines an amount of the metabolism product. The rate of metabolism may be a rate of depletion of the compound. The metabolism product may be an amount of the compound remaining after the compound's first passage through the mammalian liver (This is not necessarily limited to first pass, nor would it need to be limited to the liver. Intestinal metabolism could also be modeled). The rate of metabolism may alternatively be a rate of accumulation of a metabolite of the compound.
Patent CA-2421205-A1 (CA)
Inventor: YANO HIROYUKI
IPC: H01M8/02
Filed: 2001-09-03
Abstract: A separator for fuel cells which is excellent in conductivity, gas impermeability, strength, etc.; and a separator composition for fuel cells which comprises a resin binder having a viscosity at 150~C of 0.01 to 0.5 Pa  s and a viscosity at 25~C of 3 Pa s or higher, graphite particles contained in  an amount of 5 to 15 times by weight the amount of the resin binder, and a curing accelerator. Examples of the resin binder include an epoxy resin bind er comprising an epoxy resin and an epoxy resin hardener. Also provided is a process for producing the separator for fuel cells which comprises kneading and molding the separator composition and curing it at a temperature not low er than the curing temperature of the resin binder. The separator for fuel cell s, which is obtained by the process, has a bulk density of 1.90 g/cm3 or higher , a sheet resistance (areal pressure, 0.5 MPa) of 40 mOcm2 or lower, a gas permeability of 1x10-14 cm2 or lower, and a flexural strength of 30 MPa or higher.
Patent CA-2423619-A1 (CA)
Title: Improved system and method for case-based reasoning
Inventor: ATAMER ALLEN
IPC: G06F17/30
Filed: 2003-03-27
Abstract: A case based reasoning system and method for matching a problem case to at least one solved case. A solved case database stores solved case data correlated to a plurality of solved cases. An attribute database stores a set of attributes and observation cost data corresponding to each of the attributes, such that the observation cost data corresponding to an attribute is correlated to a cost of determining an attribute value corresponding to the attribute. A set of potential solved cases is determined. A set of relevant attributes for which at least one potential solved case has an attribute value and for which no corresponding problem attribute value has been input is determined and ranked based on the observation cost data for each relevant attribute.
Patent CA-2424182-A1 (CA)
Title: Interaxle differential control system
Inventor: RODEGHIERO RENO ANTONIO
IPC: B60K23/08
Filed: 2003-04-01
Abstract: A tractor has an interaxle differential which transmits torque from an engine driven transmission to a front axle and to a rear axle. A differential includes a planetary gear set coupled to a modulating clutch. The modulating clutch is coupled between a pair of the planetary gear elements, and is used to bring the front to rear speed differential within desired limits. A control system for controlling the clutch includes a steering angle sensor, a front wheel speed sensor and a rear wheel speed sensor. From these sensors the control system determines a desired maximum speed difference between the front and rear wheels, and controls the differential to keep the front to rear speed ratio within the desired limit.
Patent CA-2424554-A1 (CA)
Title: Antacid and laxative tablet
Inventor: KAWAMURA ISAMU
IPC: A61P1/04
Filed: 2002-07-08
Abstract: An antacid and laxative tablet comprising magnesium oxide particles as an effective component, wherein (i) the magnesium oxide particles contained in the tablet have an average secondary particle diameter measured by a laser diffraction scattering method of 0.5 to 10 µm, (ii) the content of magnesium oxide particles in the tablet is 88 wt% or more, (iii) the tablet does not become blackish and has substantially no tableting spot, and (iv) the disintegration time is 10 sec or less.     The antacid and laxative tablet of the present invention has a high content of magnesium oxide particles, a short disintegration time, does not become blackish, has no tablet trouble and no tableting spot and is suitably administered orally.
Patent CA-2424925-A1 (CA)
Inventor: MATHIVET THOMAS
IPC: C01F17/00
Filed: 2001-09-28
Abstract: Le composé d'addition d'un acide carboxylique et d'un halogénure ou d'un halogénocarboxylate de terre rare ou de gallium du même acide est obtenu par  un procédé dans lequel on fait réagir avec HX, X désignant un halogène, et dans un solvant choisi parmi les alcanes, les cyclanes et les solvants aromatiques et leurs mélanges, un carboxylate de terre rare ou de gallium, l a réaction étant réalisée avec un rapport atomique X/terre rare ou gallium inférieur à 3 dans le cas de la préparation d'un halogénocarboxylate. Le second procédé de l'invention concerne la préparation d'un composé anhydre d'addition d'un halogénure de terre rare ou de gallium et d'un composé donne ur d'azote ou d'oxygène dans lequel on prépare un composé d'addition d'un acide  carboxylique et d'un halogénure de terre rare du type précédent et on ajoute  au milieu obtenu un donneur d'azote ou d'oxygène.
Patent CA-2425164-A1 (CA)
Inventor: DOLLINGER HORST
IPC: A61P25/00
Filed: 2001-10-16
Abstract: The invention relates to new compounds of formula I  (see formula I) or the pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, X and Ar1 have the meanings given in the specification, as well as the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin) antagonists.
Patent CA-2425891-A1 (CA)
Inventor: THILLY JACQUES
IPC: G21F7/005
Filed: 2001-08-13
Abstract: L'invention concerne un système de création d'une connexion entre l'intérieur et l'extérieur d'un compartiment. Cette connexion comprend une ouverture de porte par la paroi du compartiment, un corps de connecteur qui peut s'enclencher avec la paroi et possédant un port de connexion à travers celle-ci et un couvercle amovible sur le corps de connecteur. Le corps s'enclenche avec l'ouverture de la porte et une porte intérieure dans le compartiment s'enclenche et retire le couvercle. Un mode de réalisation favori permet la réalisation d'une ligne simple de joint de confiance. Ce système est tout particulièrement adapté pour des compartiments stériles.
Patent CA-2428624-A1 (CA)
Title: Protective sleeve for a removable tip syringe
Inventor: NESBITT LANNY
IPC: A61C5/06
Filed: 2001-11-07
Abstract: A syringe sleeve (10) receives a syringe (11) without the syringe (10) dispensing tip (12). After the syringe (11) is received within the sleeve (10), the dispensing tip (12) is affixed to the syringe (11). This causes the end (50) of the sleeve (10) to open and the end (50) to be physically impinged between the tip (12) and the syringe (11). The syringe (11) is thus protected from the operative environment.
Patent CA-2430854-A1 (CA)
Inventor: MULLAY JOHN J
IPC: C10L1/00
Filed: 2001-11-05
Abstract: L'invention porte sur un procédé de fabrication d'un combustible mélangé à de l'eau consistant à émulsionner l'émulsifiant dans une quantité de combustible, puis à ajouter l'eau dans un mélange sous cisaillement élevé afin d'obtenir une émulsion de combustible concentrée en eau. Cette émulsion est ensuite diluée dans la quantité finale de combustible dans des conditions de mélange plus ou moins intime qui permettent d'obtenir un combustible émulsionné mélangé à de l'eau.
Patent CA-2431368-A1 (CA)
Title: Intraocular irrigating solution having improved flow characteristics
Inventor: DOSHI UDAY
IPC: A61K38/14
Filed: 2001-12-11
Abstract: Improved intraocular irrigating solutions are described. The solutions have enhanced viscosities that reduce the risk of damage to intraocular tissues during intraocular surgical procedures by reducing the turbulence of the solutions and dampening the movement of tissue fragments and air bubbles. The solutions preferably also have modified surface tensions that more closely resemble the surface tension of the aqueous humor.
Patent CA-2432535-A1 (CA)
Title: Device for measuring blood coagulation and method thereof
Inventor: STIENE MATTHIAS
IPC: G01N33/86
Filed: 2001-12-19
Abstract: A device and method for measuring the clotting times in a fluid, typically blood, within a microchannel whereby the onset of clotting is determined by measurement of the rate of change or value of capacitance or impedance between two electrodes situated on either side of the microchannel. There is provided a disposable test-strip (100) comprising an upper and lower support (101) and (103). A microchannel (102) is formed into the upper surface of the lower support member (103). A second substrate layer (101) is laminated on top of the support member (103), thereby closing the open microchannel (102).  Electrodes (104) are formed on the respective outer surfaces of the substrate layers and coplanar to the channel.
Patent CA-2435703-A1 (CA)
Inventor: BOSKO ROBERT S
IPC: B01D61/02
Filed: 2002-01-30
Abstract: A microbial resistant water purification and collection system (10) includes a reverse osmosis filter assembly (19) having a filter inlet in selective fluid communication with a system inlet (11) and a filter outlet (13) in fluid communication with a water storage container (12) for storing filtrate. At least a portion of the storage container is located at an elevation above the filter membrane such that filling of the storage container creates a head pressure in the storage container relative to the filter membrane to enable a backflow of filtrate therethrough. A mechanical shut-off valve (27) is interposed the system inlet (11) and the filter inlet to block fluid communication therebetween upon reaching a minimum head pressure in the storage container relative to the filter membrane.
Patent CA-2437139-A1 (CA)
Title: Insulation boards and methods for their manufacture
Inventor: LETTS JOHN B
IPC: C08G18/42
Filed: 2003-08-13
Abstract: A method for producing polyisocyanurate insulation foams, the method comprising contacting an A-side stream of reactants that includes an isocyanate with a B-side stream of reactants that include a polyol and a blowing agent, where the blowing agent includes isopentane and n-pentane in a substantial absence of cyclopentane.
Patent CA-2437806-A1 (CA)
Title: Marker pens
Inventor: BOLTON TERENCE WILLIAM
IPC: B43K8/00
Filed: 2002-02-06
Abstract: A marker pen comprises a tubular housing (1) from one end of which protrudes a first fluid retaining (14) nib replenished by fluid such as an indicator ink present in a first chamber (8) positioned within the housing, and a second fluid retaining (25) nib which also protrudes from the aforesaid end of the housing and is replenished by fluid such as an eradicator fluid present in a second chamber (21) positioned within the housing. The protruding nibs are spaced one from the other.
Patent CA-2438373-A1 (CA)
Inventor: SRINIVASAN SATCHIT
IPC: C08L23/04
Filed: 2002-02-20
Abstract: L'invention concerne un procédé de préparation d'un mélange polyoléfinique présentant une plus grande résistance à la fusion, consistant à incorporer un produit nanocomposite de polyoléfine/argile. Le mélange polyoléfinique nanocomposite modifié est utilisé pour former des articles par des opérations de traitement d'allongement et/ou d'étirage, par exemple le thermoformage, le filage par fusion, le moulage par soufflage et le moussage. L'ajout du produit nanocomposite au mélange polyoléfinique améliore la résistance au fléchissement de la polyoléfine et élargit la capacité de traitement de l'opération.
Patent CA-2438800-A1 (CA)
Title: Fabric rinse composition comprising a triazine uv absorber
Inventor: HOCHBERG ROBERT
IPC: D06L4/657
Filed: 2002-03-19
Abstract: Disclosed is a fabric rinse composition comprising a) 0.1 to 10% by weight of a UV absorber selected from a hydroxyaryl-1, 3, 5- triazine of the formula (I), wherein R1 is hydrogen; c1-c4-Alkoxy; or halogen; R2 is mono-C1-C4 alkylamino; a radical of the formula (I'); X is C2-C4 alkylen; Y1, Y2 independently from each other are C1-C4 alkyl or C1-C4 alkyl which is substituted by halogen, cyano hydroxy or C1-C4 alkoxy; or Y1 and Y2 or Y1 and Y3 together with the nitrogen atom form a 5- to 7- membered heterocycle; Y3 is hydrogene; C1-C4 alkyl; C3-C4 alkenyl; or C1-C4 alkyl, C3-C4 alkenyl which is substituted by cyano, hydroxy, C1-C4 alkoxy, phenyl or C1-C4 alkoxycarbonyl;  or Y1, Y2 and Y3 together with the binding nitrogen atom form a pyrrolidine, piperidine or morpholine radical; A is the counter ion; b) 5 to 25% by weight, based on the total weight of the composition of a fabric care ingredient; and c) the remainder being substantially water.
Patent CA-2441920-A1 (CA)
Inventor: RAICHLE KURT
IPC: H02J7/02
Filed: 2003-09-19
Abstract: A battery charger includes line-level input rectification, a high-frequency oscillator-controlled chopper circuit, multiple transformers operating in parallel, and controlled output rectification. Ilse of line-level input rectification reorders the elements of the battery charger compared to previous designs. A chopper frequency several orders of magnitude higher than that of the AC power mains is used. The use of multiple, parallel-wired transformers for voltage and current transformation eases constraints on the physical geometry of a manufactured battery charger product by permitting individual transformers, each smaller than a comparable single transformer, to be employed. Controlled output rectifiers permit power levels to be regulated dynamically.
Patent CA-2447382-A1 (CA)
Inventor: ADAMS RONALD
IPC: A61B17/00
Filed: 2002-05-22
Abstract: La présente invention concerne un ensemble distal d'un dispositif de chirurgie endoscopique, et un procédé correspondant, comporte un premier bras, et un second bras pivotant par rapport au premier bras. Chaque bras est configuré pour tenir une partie d'une fixation en deux partir à une extrémité distale du bras. Un mécanisme de fermeture est positionné à proximité de l'extrémité proximale de chacun du premier et du second bas à l'opposé de l'extrémité distale de chacun du premier et du second bras. Le mécanisme de fermeture est configurer pour bouger par rapport aux deux bras de façon à se refermer sur l'un au moins des deux bras de façon à amener les extrémités distales des bras à se rapprocher. Un organe d'actionnement est également attaché au mécanisme de fermeture que l'on peut actionner de façon à provoquer un déplacement du mécanisme de fermeture par rapport aux deux bras.
Patent CA-2447477-A1 (CA)
Inventor: SATOH HARUMI
IPC: H04W4/02
Filed: 2003-10-29
Abstract: An input power source voltage detecting unit 1 detects the input AC power source voltage on an electronic device, and a country discriminating unit 2 discriminates the country with the electronic device present therein according to the detected voltage. An operation environment presetting unit 5 presets the electronic device to operation environments of the country discriminated by the country discriminating unit 2.
Patent CA-2447493-A1 (CA)
Inventor: ALLOR RICHARD L
IPC: B22D23/00
Filed: 2003-10-29
Abstract: One method of the present invention includes introducing a slurry into a mold unit comprised of a mold contained within a casting receptacle and lowering the temperature of the slurry to freeze the slurry and form a freeze-cast substrate while controlling temperature gradients within the mold unit to minimize distortion in the freeze-cast substrate. Another method includes introducing a slurry into a mold unit comprised of a mold contained within a casting receptacle, placing insulation material around at least a portion of the casting receptacle to minimize distortion in the freeze-cast substrate by controlling temperature gradients within the mold unit, and lowering the temperature of the slurry to freeze the slurry to form a freeze-cast substrate.
Patent CA-2447730-A1 (CA)
Inventor: SUZUKI SHIGEAKI
IPC: C07C45/50
Filed: 2002-06-05
Abstract: Lithium p-diarylphosphinobenzenesulfonates represented by the general formula (I); a process for preparing the same; a group VIII metal complex composed of a group VIII metal compound and the above lithium p-diarylphosphinobenzenesulfonate coordinating thereto and a process for hydroformylation with the complex (I) wherein R1 and R2 are each optionally substituted aryl. Hydroformylation with the complex permits easy and industrially advantageous production of aldehydes.
Patent CA-2448971-A1 (CA)
Title: Chimeric flavivirus vectors
Inventor: KLEANTHOUS HAROLD
IPC: C12Q1/68
Filed: 2002-05-31
Abstract: The invention provides chimeric flavivirus vectors including foreign peptide s inserted into the envelope proteins of the vectors and methods of using thes e vectors.
Patent CA-2449129-A1 (CA)
Title: System for cooling a heated juice by partial low-pressure evaporation
Inventor: CADIOT DOMINIQUE
IPC: C12G1/02
Filed: 2002-05-29
Abstract: A system for cooling a heated juice by partial low-pressure evaporation, said juice comprising a charged liquid, preferably juice from a harvested crop, said system comprising a vat in which the juice is subjected to various pressure reductions, said vat (4) comprising at least two compartments(5,6) which communicate with each other by means of a pulsed-effect valve, said juice being subjected to two different decreasing pressure reductions in said compartments, each compartment being connected to a condenser (19,25) which can condense the vapor produced by the pressure reduction. The condensers are serially mounted or parallel mounted and connected to a common vacuum pump (34) by means of at least one control valve (18) which can permanently adjust the pressure in each condenser to a value which is lower than the saturating vapor pressure corresponding to the temperature of the vapor created in each of the condensers. The invention is characterized in that the compartments (5,6) of the vat are superposed and communicate with each other therein by means of an opening (8) through which the juice passes, said opening being closed either fully or partially by a variably positioned shutter element, creating a pulsed effect in order to remove the solid particles contained in the juice.
Patent CA-2450190-A1 (CA)
Title: Method and device for fine grinding of mineral particles
Inventor: ARTRU PHILIPPE
IPC: C22B1/00
Filed: 2002-06-25
Abstract: A method for fine grinding of mineral particles consists of producing beads (38), made from steel with a high carbon content, or cast iron, by means of atomisation with a granular size range less than 15 mm and mixing the beads (38) with balls (36), made from steel or cast iron with dimensions between 20mm and 120mm, in a rotating grinding mill, the proportion by weight of beads (38) depending on the granular size of the mineral particles for grinding and the desired reduction ratio.
Patent CA-2451884-A1 (CA)
Inventor: KIRCHHOFER FRITZ
IPC: A61M5/315
Filed: 2002-07-22
Abstract: An administering apparatus comprising a dosing device, the administering apparatus comprising:  (a) a casing (1, 3, 11) comprising a reservoir (2) for a product which can be delivered;  (b) a piston which can be shifted in the reservoir (2) in an advancing direction towards a reservoir outlet, in order to deliver product;   (c) a piston rod (4);   (d) a dosing and drive element (12) using which a dosing movement for selecting a product dosage and a delivery movement for delivering the product dosage can be performed relative to the casing (1, 3, 11), and which is in an engagement with the piston rod (4) which slaves the piston rod (4) during the dosing movement, but which allows a delivery movement of the dosing and drive element (12) relative to the piston rod (4);   (e) and a dosage setting member (9) which is moved in the advancing direction by the dosing and drive element (12) during the delivery movement, and which engages with each of the piston rod (4) and the casing (1, 3, 11), such that it can only be moved in the advancing direction jointly with the piston rod (4) and is moved counter to the advancing direction, relative to the piston rod (4), by the dosing movement.
Patent CA-2456519-A1 (CA)
Title: Oral compositions for the treatment of scalp disorders
Inventor: DI PIERRO FRANCESCO
IPC: A61K31/4172
Filed: 2001-11-14
Abstract: Pharmaceutical and/or cosmetic compositions for the treatment and the prevention of scalp disorders, containing as active components extracts of Serenoa repens and of Vitis vinifera.
Patent CA-2456822-A1 (CA)
Inventor: MANLEY RICHARD G
IPC: B22D25/00
Filed: 2002-08-16
Abstract: L'invention concerne un procédé de moulage d'un article constitué d'une mousse de métal. Ledit procédé consiste à placer une coquille pourvue d'une cavité au-dessus d'un bain de métal fondu et à mettre le bain sous pression, de manière à remplir ladite cavité avec le métal fondu. On fait alors barboter un gaz à travers le métal fondu pour former une mousse. La mousse est alors formée dans la cavité de la coquille. Une fois que la mousse de la cavité est solidifiée, la pression dans le bain est rela^chée et l'article formé est retiré. Un appareil conçu pour la mise en oeuvre de ce procédé comprend une coquille placée au-dessus du bain, ladite coquille comportant une cavité en communication fluidique avec le bain. Le bain est muni d'un dispositif de mise sous pression et d'un dispositif d'évacuation de gaz, ainsi que d'un orifice alimentation en gaz servant à former la mousse.