baber/WOPTO huggingface dataset:
Patent AU-3914893-A (AU)
Title: Methods, compositions and devices for maintaining and growing human stem and/or hematopoietic cells
Inventor: PALSSON BERNHARD O
IPC: C12M3/06
Filed: 1993-03-04
Abstract: Methods, compositions and devices are provided for the growth of human stem and/or hematopoietic cells in culture. Bioreactors (106) are provided in which diverse cell types are simultaneously-cultured in the presence of appropriate levels of nutrients and growth factors substantially continuously maintained in the bioreactor (106) while removing undesirable metabolic products. This simultaneous culture of multiple cell types successfully reconstructs hematopoietic tissue ex vivo. Optionally, at least one growth factor is provided through excretion by transfected stromal cells, particularly heterologous cells. Means are provided for maintaining the stromal cells (112) and hematopoietic cells (110) separately, and to allow for harvesting of both the adherent (110, 112) and non-adherent cells (114).
Patent AU-3954795-A (AU)
Title: Apparatus for coating substrates with inductively charged resinous powder particles
Inventor: WILLIAMS BARBARA E
IPC: B05B5/03
Filed: 1995-10-03
Abstract: An apparatus for improving the electrostatic charge developed on a resin powder composition for electrostatic coating of solid objects and the method of application thereof. The apparatus comprises a device for charging the powder by electrical induction/conduction such that the powder particles have a resistivity of from about 109 to about 1013 ohm.meters at 20 percent relative humidity and spraying the charged powder onto an grounded solid object to which it adheres prior to the thermal fusing to produce a permanent finish.
Patent AU-4007599-A (AU)
Title: Methods for amyloid removal using anti-amyloid antibodies
Inventor: SOLOMON ALAN
IPC: A61P25/28
Filed: 1999-05-21
Abstract: Methods and related immunoglobulin peptides and fragments thereof are disclosed that enhance the cell-mediated immune response of a patient to deposits of amyloid fibrils. These methods exploit the opsonizing effect of antibodies directed toward amyloid material or its component parts.
Patent AU-4152589-A (AU)
Title: Substituted imidazol(2,1-b)quinazolin-5(3H)-ones and related tricyclic compounds and use as bronchodilators
Inventor: PEET NORTON P
IPC: C07D471/14
Filed: 1989-09-18
Abstract: The present invention is directed to a group of compounds which are imidazol[2,1-b]quinazolin-5(3H)-ones, related tricyclic compounds, and pharmaceutically acceptable salts thereof. These compounds are useful as bronchodilators. These compounds are prepared by the reaction of an appropriate hydrazine with an appropriate 1-substituted-2-methyl-2-imidazoline or chemically equivalent compound.
Patent AU-4583696-A (AU)
Title: Structured occlusive dressings
Inventor: SCHIRALDI MICHAEL T
IPC: A61F13/00
Filed: 1996-02-29
Abstract: This invention relates to a composition containing a hydrophobic solvent, a network polymer and a flow control agent which is useful in healing wounds. The composition of this invention may be applied directly to a wound to create a structured occlusive dressing. The dressings of this invention do not migrate, but maintain their integrity at skin temperature, and encourage the creation of a moist wound environment while protecting the wound in order to accelerate healing.
Patent AU-4594401-A (AU)
Title: Human urothelial cell specific uroplakin transcriptional regulatory sequences, vectors comprising uroplakin-specific transcriptional regulatory sequences, and methods of use thereof
Inventor: YU DE-CHAO
IPC: A61K48/00
Filed: 2001-03-21
Abstract: The invention provides new urothelial cell specific transcriptional regulatory sequences derived from human uroplakin II (hUPII), as well as polynucleotide constructs such as adenoviral vectors and methods of using hUPII-derived TREs. Additionally, the invention provides adenoviral vectors comprising a gene, preferably an adenovirus gene, under transcriptional control of a urothelial cell-specific transcriptional regulatory element (TRE). These vectors display urothelial cell-specific cytotoxicity, which is especially useful in the context of bladder cancer, in which destruction of these cells is desirable. The invention further provides compositions and host cells comprising the vectors, as well as method of using the adenoviral vectors.
Patent AU-4746090-A (AU)
Title: Substituted hexahydro-indenopyrroles, -indenopyridines, and -benzoisoindoles as 5-HT selective agents
Inventor: DEBERNARDIS JOHN F
IPC: A61K31/435
Filed: 1989-12-07
Abstract: Substituted 8-alkoxy-1,2,3,3a,8,8a-hexahydroindeno[1,2-c]pyrroles; 5-alkoxy-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-c]pyridines; and 9-alkoxy-2,3,3a,4,5,9a-hexahydro-1H-benz[e]isoindoles are selective 5-HT receptor agents and are thus useful in the treatment of anxiety, depression, and hypertension.
Patent AU-4780193-A (AU)
Title: Hybrid oligonucleotide phosphorothioates
Inventor: METELEV VALERI
IPC: A61K31/713
Filed: 1993-07-22
Abstract: The invention provides hybrid oligonucleotides having phosphorothioate or phosphorodithioate internucleotide linkages, and both deoxyribonucleosides and ribonueleosides or 2'-substituted ribonucleosides. Such hybrid oligonucleotides have superior properties of duplex formation with RNA, nuclease resistance, and RNase H activation.
Patent AU-4835293-A (AU)
Title: Distributor head for forming a tubular profile from one or more streams of extruded thermoplastic material
Inventor: VEEN HENDRIK WILLEM
IPC: B29C48/09
Filed: 1993-07-30
Abstract: PCT No. PCT/NL93/00165 Sec. 371 Date Feb. 13, 1995 Sec. 102(e) Date Feb. 13, 1995 PCT Filed Jul. 30, 1993 PCT Pub. No. WO94/04341 PCT Pub. Date Mar. 3, 1994A distributor head (1) for forming a tubular profile from one or more streams of thermoplastic material, which distributor head comprises at least an inlet orifice (10, 12, 14) for a stream of plastics material, which can be connected to an extruder, and an outlet orifice (20, 22, 24) of annular cross section. The distributor head comprises at least one flow channel system (30, 32, 34) which is connected to an inlet orifice of the distributor head by means of an inlet channel (36, 38, 40), which inlet channel, in a number of stages of branchings and intermediate flow channels (60, 62, 64), branches into a number of outlet channels (66, 68, 70) terminating on a periphery around the center line of the outlet orifice, which outlet channels open into the outlet orifice.
Patent AU-4841693-A (AU)
Title: Vaccines against group c neisseria meningitidis
Inventor: TAI JOSEPH Y
IPC: A61P31/04
Filed: 1993-08-30
Abstract: An immunogenic conjugate comprising a modified group C meningococcal polysaccharide (GCMP) coupled to a carrier molecule. The GCMP is modified by O-deacetylation to a varying extent. This modified GCMP conjugate stimulates a strong immunogenic response. The antiserum, produced by immunization with this conjugate, is cross-reactive with the native polysaccharide. In addition, these antisera elicit a class of antibodies that have potent bactericidal activity.
Patent AU-4915099-A (AU)
Title: Method for making, by blow moulding, plastic hollow bodies, device and installation therefor
Inventor: EMMER GERARD
IPC: B29C49/78
Filed: 1999-07-22
Abstract: To blow plastic hollow bodies, each mold (7) has its respective compression chamber (21) connected to it, constituted by a cylinder (20)-piston (19) assembly; pressure is initialized in the chamber; the fluid is compressed in the chamber; the chamber is connected (22, 24, 25) with the blank (9) when the piston position attains a predetermined position and chamber volume continues to be reduced to complete the blowing. The invention can be applied in particular to the blowing of small-volume hollow bodies.
Patent AU-4999193-A (AU)
Title: Recombinant equine herpesviruses
Inventor: COCHRAN MARK D
IPC: C12N7/00
Filed: 1993-08-06
Abstract: The present invention relates to a non-naturally occurring, recombinant equine herpesvirus. The invention also relates to a recombinant equine herpesvirus capable of replication which comprises viral DNA from a species of equine herpesvirus and foreign DNA, the foreign DNA being inserted into the equine herpesviral DNA at a site which is not essential for replication of the equine herpesvirus. The invention also relates to DNA encoding the US2 protein of an equine herpesvirus. The invention relates to homology vectors for producing recombinant equine herpesviruses which produce recombinant equine herpesviruses by inserting foreign DNA into equine herpesviral DNA. The invention further relates to a method of producing a fetal-safe, live recombinant equine herpesvirus.
Patent AU-5077700-A (AU)
Title: Adhesive composition and protective film containing the same
Inventor: CLIPPELEIR JOHAN MARCEL MARIA
IPC: C09J7/02
Filed: 2000-06-09
Abstract: The present invention relates to an adhesive composition comprising: (i) a block copolymer containing at least two poly(monovinyl aromatic hydrocarbon) blocks and at least one hydrogenated poly(conjugated diene) block; (ii) 20 to 80 parts by weight of an at least partially hydrogenated tackifying resin per 100 parts by weight of block copolymer; (iii) 0 to 40 parts by weight of aromatic resin per 100 parts by weight of block copolymer; (iv) 10 to 60 parts by weight of a polybutene-1 per 100 parts by weight of block copolymer; and (v) 0 to 25 parts by weight of plasticiser per 100 parts by weight of block copolymer. The present invention further relates to a process for preparing pellets containing the adhesive composition and to a protective film comprising a substrate layer and an adhesive layer comprising the adhesive composition as defined above. The present invention further relates to a process for preparing a protective film by co-extrusion and to articles containing a protective film.
Patent AU-5120796-A (AU)
Title: DNA fragment, recombination vector containing the same and method for expressing foreign genes using the same
Inventor: MORIOKA SHINJI
IPC: C12N9/16
Filed: 1996-03-28
Abstract: A novel DNA which has a sequence different from those of publicly known DNAs capable of promoting the expression of an alien gene and can remarkably promote the expression of an alien gene. An isolated DNA fragment having a base sequence represented by SEQ ID NO:1 in the Sequence Listing; and an isolated DNA fragment represented by this base sequence wherein one or more nucleotides have been added, inserted, deleted or replaced and having the effect of promoting the expression of a gene located in the downstream thereof. <IMAGE>
Patent AU-5323299-A (AU)
Title: Hardware-efficient transceiver with delta-sigma digital-to-analog converter
Inventor: BUTTERFIELD DANIEL KEYES
IPC: H04B1/40
Filed: 1999-07-27
Abstract: A hardware-efficient transceiver. The transceiver includes a digital circuit for converting baseband signals to intermediate frequency signals. A signal source provides a first periodic signal of a first frequency. A direct digital synthesizer provides a second periodic signal of a second frequency from the first periodic reference signal. An upconverter circuit digitally upconverts the baseband signals to digital intermediate frequency signals using the second periodic signal A digital-to-analog converter converts the digital intermediate frequency signals to analog intermediate frequency signals using the first periodic signal. In the transceiver implementation, the digital circuit upconverts a first transmit signal from a first frequency to a second frequency in response to the second periodic signal and provides a digital transmit signal in response thereto. A second circuit is provided for converting the digital transmit signal to an analog transmit signal. Transmit and receive circuitry are provided for transmitting the analog transmit signal and receiving an analog receive signal, respectively. In a specific embodiment, the analog receive signal is digitally downconverted to provide a digital receive signal in response to a second periodic signal. A significant feature of the invention resides in the provision of the first and second periodic signals with a single local oscillator. A direct digital synthesizer is included for generating one of the reference signals from the output of the local oscillator. The transmit circuit includes a delta-sigma digital-to-analog converter having the first periodic signal as an input The delta-sigma digital-to-analog converter has a low-bit digital-to-analog converter and a delta-sigma modulator. In the illustrative embodiment, the low-bit digital-to-analog converter is a 1-bit digital-to-analog converter and the delta-sigma modulator is a sixth order delta-sigma modulator. The delta-sigma modulator includes amplifiers with approximately the following gains: 3/2, -3/4, 1/8.
Patent AU-5337890-A (AU)
Title: Molecular cloning of genomic and cdna sequences encoding cellular receptors for poliovirus
Inventor: RACANIELLO VINCENT
IPC: A61K35/76
Filed: 1990-03-09
Abstract: The subject invention provides an isolated nucleic acid molecule which comprises nucleic acid encoding a polypeptide which has the biological activity of a receptor for picornavirus and in addition, provides a purified polypeptide which has this activity. The subject invention also provides a method for inducing the production of a polypeptide which includes the use of expression vectors in a host vector system. Therapeutic compositions comprising purified polypeptides which have the biological activity of a receptor for picornavirus are also provided for as are methods of treating and preventing human poliovirus infection. Further, the subject invention provides a method of producing a transgenic animal expressing human picornavirus. The subject invention provides a method of testing the efficacy of a picornavirus vaccine which comprises administering the vaccine to a transgenic animal described above and determining whether the resulting transgenic animal is protected from infection by human picornavirus. Lastly, a method of testing the virulence of a picornavirus vaccine is provided.
Patent AU-5504694-A (AU)
Title: Substituted amic acid derivatives
Inventor: NOMOTO TAKASHI
IPC: C07C69/34
Filed: 1994-02-11
Abstract: A compound of the formula (I) or its pharmaceutically acceptable salt or ester: <CHEM>  wherein each of <CHEM> which are the same or different, is an aryl group or a heteroaromatic ring group; A is a C3-8 linear saturated or unsaturated aliphatic hydrocarbon group which may have substituent(s) selected from the group consisting of a lower alkyl group, a hydroxyl group, a lower alkoxy group, a carboxyl group, an aryl group and an aralkyl group; Q is a single bond or a group of the formula -CO-O-, -O-CO-, -CH2CH2-, -CH=CH-, -OCH2-, -SCH2-, -CH2O- or -CH2S-; each of R<1>, R<2>, R<3> and R<4> which are the same or different, is a hydrogen atom, a halogen atom, a lower alkyl group, a hydroxyl group, a lower alkoxy group, or an aryl or heteroaromatic ring group which may have substituent(s) selected from the group consisting of a halogen atom, a lower alkyl group and a lower alkoxy group; each of R<5>, R<6> and R<7> which are the same or different, is a hydrogen atom or a lower alkyl group; and R<8> is a hydrogen atom, a lower alkyl group, a lower alkenyl group, a lower alkynyl group or an aralkyl group, provided that when Q is a single bond, <CHEM> are not simultaneously 4-chlorophenyl groups.a
Patent AU-5716500-A (AU)
Title: Aerosol for dispensing a liquid
Inventor: HEIJDEN EDGAR IVO MARIA VAN DE
IPC: B65D47/34
Filed: 2000-06-23
Abstract: An aerosol for dispensing a liquid, in particular in the form of a foam, at least including a liquid container and a dispensing assembly which is coupled thereto. The dispensing assembly includes a liquid pump and an actuating head, the actuating head having a closed, circumferential protective cap. The aerosol furthermore includes a circumferential recess, into which the protective cap can move, which recess includes a closed inner wall, an outer wall and a base, and one or more outlet openings are present in the vicinity of the base of the recess, wherein the shape of the recess is such that the inner wall, on the side which is remote from the base, is at a radial distance p from the protective cap, which distance p is greater than the usual clearance distance of the protective cap with respect to the inner wall.
Patent AU-5720386-A (AU)
Title: Self-checking, dual railed, leading edge synchronizer
Inventor: CHANDRAN SRIKUMAR R
IPC: G06F1/12
Filed: 1986-05-07
Abstract: The present invention relates to a digital logic circuit and method for synchronizing the leading edges of a skewed true-complement signal pair. The circuit of the present invention is comprised of two similar, interconnected circuit halves, each of which includes three D flip-flop stages. The outputs from the second D flip-flop stages from the two circuit halves are applied to the two inputs of two identical logic gates, such that the signal pair is synchronously transmitted to a pair of output gates through a third D flip-flop stage in each circuit half. The second D flip-flop stages also prevent metastable states from reaching the synchronizer output. Metastable states may result if the input setup time is violated for the first D flip-flop stages. The third D flip-flop stage in each circuit half also eliminates any signal irregularities generated in the logic circuitry from appearing on the synchronizer output lines. The present invention is self-checking in that any single fault in the input signals or in the synchronizer circuit itself will result in the synchronizer output pair not having a true complement relationship.
Patent AU-5729990-A (AU)
Title: N-phenylalkyl substituted alpha-amino carboxamide derivatives and process for their preparation
Inventor: DOSTERT PHILIPPE
IPC: A61K31/4402
Filed: 1990-05-25
Abstract: N-phenylalkyl substituted  alpha -amino carboxamide derivatives of formula (I) <CHEM> wherein R is C1-C8 alkyl, C3-C8 cycloalkyl, furyl, thienyl, pyridyl or unsubstituted or substituted phenyl; A is a -(CH2)m- or -(CH2)p-X-(CH2)q- group wherein X is -O-, -S- or -NR4-; R1, R2, R3, R min 3, R4, n, m, p and q are as herein defined; and each of R5 and R6 is independently hydrogen or C1-C6 alkyl, and the pharmaceutically acceptable salts thereof, are active on the central nervous system and can be used as anti-epileptic, anti-Parkinson, neuroprotective, antidepressant, antispastic and/or hypnotic agents in mammals.
Patent AU-5786496-A (AU)
Title: Removable core cylinder lock
Inventor: WIDEN BO
IPC: E05B9/08
Filed: 1996-05-17
Abstract: A removable core cylinder lock includes a cylinder lock casing and a removable cylinder lock core inserted into the casing. The lock core has an upper massive part with a row of holes for accommodating locking tumblers, and a lower part defining a cylindrical bore in which a cylindrical, rotatable key plug is located. The lower part defining the cylinder bore of the cylinder lock core is partially cut away so as to form an axially elongated chamber accommodating a transversely movable retainer member and leaving a continuous lower wall portion. The retainer member has an axial length, which corresponds to at least half of the axial length of the row of holes in the upper massive part, and a limited circumferential extension, which is substantially supplementary to the continuous lower wall portion so as to define the cylindrical bore.
Patent AU-5826298-A (AU)
Title: Synthesis of terfenadine and derivatives
Inventor: SENANAYAKE CHRIS HUGH
IPC: C07D317/30
Filed: 1998-01-20
Abstract: Processes for preparing compounds having the general formula: wherein R1a is protected carboxy, carboxy, hydroxymethyl, protected hydroxymethyl, or methyl are disclosed. Processes of the invention begin with a starting material of the general formula IV wherein R1 and R2 are as defined in the specification.
Patent AU-5910180-A (AU)
Title: Muramyldipeptide derivatives
Inventor: SHIBA T
IPC: A61K31/70
Filed: 1980-06-06
Abstract: Muramyldipeptide derivatives of the formula (I):   <IMAGE> (I) wherein X represents an amino acid residue such as of L-alanine, L-serine, L-valine, glycine, etc., and Y represents a group  <IMAGE> wherein R1 represents a hydrogen atom, an alkyl group of 1 to 6 carbon atoms, a carboxamide group or a carboxyl group, n represents an integer of 1 to 6, A represents a straight or branched chain, saturated or unsaturated aliphatic hydrocarbon residue of 7 to 30 carbon atoms, and "Acyl" means an acyl group of an aliphatic carboxylic acid having 2 to 6 carbon atoms. These compounds have excellent adjuvant activity and/or prophylactic and therapeutic effects against microbial infections.
Patent AU-5964094-A (AU)
Title: Gastrostomy catheter system
Inventor: MCNEELY GWYN F
IPC: A61J15/00
Filed: 1994-01-04
Abstract: A system and method for inserting a gastrostomy catheter through a passageway formed through the abdominal and stomach walls of a patient. The gastrostomy catheter is mounted onto a dilatation catheter with a dilatation member such as an inelastic balloon on the distal extremity thereof. An introducer needle is first advanced through the walls of the patient's abdomen and stomach into the interior of the stomach and then a guidewire is advanced through the inner lumen of the needle into the stomach interior. The gastrostomy catheter-dilatation catheter assembly is advanced over the guidewire until the balloon on the dilatation catheter is in proper position crossing both the abdominal and gastric walls. Upon inflation of the balloon on the dilatation catheter, the passageway is expanded enough so that the gastrostomy catheter can be advanced therethrough to dispose the distal end of the gastrostomy catheter within the interior of the stomach. The balloon on the distal end of the gastrostomy catheter is inflated so as to form an internal retention member and the catheter withdrawn in order to urge the inflated balloon against the stomach wall. Preferably, the gastrostomy catheter has an external retention ring on the shaft thereof which is slid against the exterior of the patient's abdomen to seal the passageway through the abdominal wall.
Patent AU-5998490-A (AU)
Title: Bacillus thuringiensis var. donegani, preparate or toxin obtained from it
Inventor: CIDARIA DANTE
IPC: A01N63/50
Filed: 1990-07-30
Abstract: Disclosed is a Bacillus thuringiensis var. donegani, pathotype C, NCIMB 40152 and a preparation or toxin obtained therefrom, endowed with insecticidal activity against Coleoptera.
Patent AU-6150000-A (AU)
Title: Leather tanning
Inventor: JONES CHRISTOPHER RAYMOND
IPC: C14C3/08
Filed: 2000-06-14
Abstract: A mixture of THP and a moderator is used to tan leather. The moderator is selected from metaphosphates and polyhydroxy or polypyrolidyl compounds such as glycerol, carboxydrates PVA or PVP.
Patent AU-6152499-A (AU)
Title: Composite devices incorporating biological material and methods
Inventor: LYNGBERG OLAV K
IPC: G01N33/50
Filed: 1999-09-17
Abstract: The present invention provides composite biological devices that include biological material as an integral component thereof. The devices can be used for measuring metals, for example, particularly toxic metals such as mercury.
Patent AU-6168086-A (AU)
Title: Taste masking compositions
Inventor: DAMANI NALINKANT CHUNILAL
IPC: A61K9/22
Filed: 1986-08-22
Abstract: This invention relates to drug-polymer matrix compositions comprising an active ingredient having an amino or amido group and a pharmaceutically acceptable copolymer having a plurality of carboxylic acid and ester groups wherein the matrix dissociates in a media having a pH of less than 4, thereby releasing the active ingredient into the media.