baber/WOPTO huggingface dataset:
Patent CA-2464214-C (CA)
Title: Protein kinase and phosphatase inhibitors, methods for designing them, and methods of using them
Inventor: HANGAUER DAVID G JR
IPC: A61K31/427
Filed: 2002-10-19
Granted: 2011-02-08
Abstract: The present invention provides a method for identifying inhibitors of protein kinases and/or protein phosphatases. Methods are also provided for inhibiting protein kinase and/or protein phosphatase activity. Specific non-peptide protein tyrosine kinase and/or protein phosphatase inhibitors are provided.  The protein kinase or protein phosphatase inhibitors of the present invention may be used to treat a number of conditions in patients, including cancer, psoriasis, arthrosclerosis, immune system activity, diabetes, or obesity. In addition, the present invention provides a method for protecting against or treating hearing loss in a subject. This method involves administering an effective amount of a protein tyrosine kinase inhibitor to the subject to protect against or to treat hearing loss.
Patent CA-2468136-C (CA)
Inventor: VAN DER SPEK ALEXANDER MICHAEL
IPC: E21B37/00
Filed: 2002-11-26
Granted: 2011-02-22
Abstract: L'invention concerne un générateur d'électricité thermoacoustique (3) conçu pour produire de l'électricité à l'intérieur ou à proximité d'une conduite de gaz (2), telle qu'un tube de production dans un puits de production de gaz. Le générateur d'électricité décrit dans cette invention comprend une cavité de résonance acoustique (7) qui est dotée d'une admission (8) définie par un orifice ménagé dans la paroi de la conduite (2) ou d'une installation placée à l'intérieur de la conduite (2) de manière à créer une acoustique stationnaire dans la cavité de résonance (7) en réaction à l'écoulement de gaz dans la conduite (2), et un corps perméable (9) situé dans la cavité de résonance (7), des points chauds et/ou froids se formant sur le corps en fonction de la dilatation ou de la compression adiabatique. Un dispositif thermoélectrique (10), tel qu'un élément Peltier, est connecté aux points froids et/ou chauds du corps perméable (9) afin de produire de l'énergie électrique en réaction à l'augmentation ou à la baisse de la température du corps perméable (9), qui peut dépasser les 50·C.
Patent CA-2468707-C (CA)
Title: The use of indigestible oligosaccharides to improve the health and productivity of ruminant animals
Inventor: LANE ROWAN LINDSAY
IPC: A23K1/18
Filed: 2002-12-02
Granted: 2011-11-22
Abstract: A method of improving the health and production of ruminant animals, the method including the step of orally administering to the animal an effective amount of an indigestible oligosaccharide selected from the group of gluco-oligosaccharides and isomalto-oligosaccharides.
Patent CA-2468977-C (CA)
Title: Bracing system for stringed instrument
IPC: G10D3/02
Filed: 2002-12-12
Granted: 2008-08-05
Abstract: In accordance with the invention, a sound box for an instrument is provided exhibiting a 3-D bracing system. The bracing system comprises a plurality of braces on both the sound board and the bottom board of the sound box. The braces exhibit varying heights and configurations to, among other things, increase the strength without increasing the weight unnecessarily.
Patent CA-2470484-C (CA)
Title: A combination comprising combretastatin and anticancer agents
Inventor: BISSERY MARIE-CHRISTINE
IPC: A61K33/243
Filed: 2002-03-15
Granted: 2009-10-13
Abstract: An antitumor combination comprising a stilbene derivative and an anticancer compound selected from the group consisting of taxanes, alkylating agents, antimetabolites, vinca alkaloids, epidophylloptoxins, and antibiotics as the active ingredients is provided. There are also provided methods of using these pharmaceutical preparations for the treatment of solid carcinomas and the like.
Patent CA-2471520-C (CA)
Title: Flexible stent and method of making the same
Inventor: HOLLOWAY KEN A
IPC: A61F2/00
Filed: 2003-03-18
Granted: 2010-11-30
Abstract: A stent (10) that can be made of self-expandable members (14) and balloon expandable members (16) is described. The members can be held together by a polymer layer, polymer rings or discreet polymer connectors (13, 48, 58, 68). Methods of making and using the stent are also described.
Patent CA-2476498-C (CA)
Title: Thermal spraying instrument
Inventor: VARDELLE MICHEL
IPC: B23K10/00
Filed: 2003-02-28
Granted: 2011-01-04
Abstract: The invention relates to a device and method for controlling the operation of a thermal spray torch (12). The inventive device and method are characterised in that an on-board camera (54) and pyrometer (70) are used to measure the properties of the jet (16) and the temperature of the deposit (24) on the part (22) and in that the correction to be made to the supply parameters of the torch (12) is deduced. Furthermore, the invention is characterised in that the corrected parameters are sent to the cabinet (30) that controls the torch (12).
Patent CA-2476600-C (CA)
Title: Radiation detector arrangement comprising multiple line detector units
Inventor: FRANCKE TOM
IPC: G01T1/185
Filed: 2003-02-14
Granted: 2012-10-30
Abstract: A radiation detector arrangement for imaging of an object comprises multiple line detector units (41), each being arranged for one-dimensional imaging of the respective ray bundle. The detector units are arranged parallel in a two-dimensional array. The detector units are sited in rows (44; 61) and stacks (45; 63), the rows being parallel with the detector unit and the stacks being orthogonal thereto, where the one-dimensional detector units in each row are together capable of detecting the object in one dimension. A device (87-89, 91) is provided for moving the detector units relative the object parallel with the stacks at least a distance corresponding to the distance (s1~) between two adjacent detector units in the stacks.
Patent CA-2477390-C (CA)
Title: Small particle analysis by laser induced incandescence
Inventor: SNELLING DAVID R
IPC: G01N15/02
Filed: 2004-08-12
Granted: 2011-09-27
Abstract: The method and apparatus of laser-induced incandescence (LII) to analyze characteristics of submicron-sized particles are described. LII is recognized as a good tool for determining the characteristics of small particles in a gas, e.g., volume fraction, particle size, and specific surface area. It uses the fact that the incandescence signal is proportional to the volume of the particles. It also uses the fact that transient cooling is dependent on the specific surface area of the particle, which is related to diameter of the particle. In LII, particles are heated by a pulsed laser light beam to a temperature where incandescence from the particles can be distinguished from ambient light. The temperature of particles and their volume fraction governs the incandescence. The temperature decay rate is proportional to the primary particle size. The invention uses an optical arrangement that ensures a near-uniform laser energy distribution spatial profile. The invention also uses a low fluence laser beam pulse to avoid evaporation of particles. Without significant evaporation and with a uniform energy profile, accurate and precise measurements can be conducted more easily and reliably.
Patent CA-2479443-C (CA)
Title: Vacuum truck solids handling apparatus
Inventor: POBIHUSHCHY VICTOR
IPC: E02F3/88
Filed: 2004-08-16
Granted: 2009-04-21
Abstract: A vacuum truck solids handling apparatus includes a truck having an internal combustion engine and a truck frame. A vacuum source, a solids collection container and a separator assembly are all mounted on the truck frame. The separator assembly is adapted to~ separate solids from a fluid stream drawn under vacuum by the vacuum source. The separator assembly has a pivotally mounted discharge, which pivots between a closed discharge position and an open discharge position. In the closed discharge position, the discharge discharges solids into the solids collection container. In the open discharge position, the discharge discharges solids externally.
Patent CA-2479704-C (CA)
Title: Melanges d'homopolymeres de forte densite
Inventor: SWABEY JOHN WILLIAM
IPC: C08J5/18
Filed: 2004-08-31
Granted: 2013-08-13
Abstract: Mélange d'homopolymères d'éthylène contenant au moins un composant présentant un poids moléculaire très faible et une distribution du poids moléculaire très limitée. Le mélange présente une densité étonnamment élevée et de faibles produits extractibles à l'hexane. Le mélange convient à la fabrication d'une grande variété de produits de plastique, notamment les produits extrudés et les produits moulés. La pellicule plastique préparée à partir des mélanges de la présente invention présente une faible transmission de la vapeur d'eau.
Patent CA-2481513-C (CA)
Inventor: DEPOOT KAREL JOZEF MARIA
IPC: C11D1/04
Filed: 2003-05-15
Granted: 2009-02-17
Abstract: The present invention relates to a liquid softening through the wash laundry detergent composition comprising: (a) at least 0.5% by weight of the composition, of a fabric softening silicone; and (b) a fatty acid; and (c) a surfactant system, the surfactant system comprising: (i) at least 75% by weight of the surfactant system, of a non-alkoxylated anionic surfactant; and (ii) less than 25% by weight of the surfactant system, of an alkoxylated surfactant; and (d) one or more laundry detergent adjunct ingredients. This wash laundry detergent composition provides not only softening but also improved cleaning and whiteness-maintenance performance.
Patent CA-2485136-C (CA)
Inventor: BERGER JACOB
IPC: A61P25/16
Filed: 2003-05-05
Granted: 2011-12-20
Abstract: The present invention provides a compound which has 5-HT6receptor affinity of the formula (I): a pharmaceutically acceptable salt or a prodrug thereof, where R1, R2, R3, R4, R5, R6, R7, R8, R9, Y, Z1, m, n, and p are as defined herein. The present invention also provides compositions comprising, methods for using, and methods for preparing Compound of Formula (I).
Patent CA-2488796-C (CA)
Title: Digital image encoding and decoding method and digital image encoding and decoding device using the same
Inventor: BOON CHOONG SENG
IPC: H04N19/61
Filed: 1997-01-21
Granted: 2005-11-15
Abstract: The present invention provides an encoder and a decoder of digital picture data, and the encoder/decoder can realize high precision transform with less quantity of transferred data, when a parameter of the digital picture data is not an integer but has numbers of digits, to which the Affine transformation can be applicable. The encoder/decoder comprises the following elements: (a) picture compression means for encoding an input picture and compressing the data, (b) coordinates transform means for outputting coordinate data which is obtained by decoding the compressed data and transforming the decoded data into a coordinate system, (c) transformation parameter producing means for producing transformation parameters from the coordinates data, (d) predicted picture producing means for producing predicted picture from the input picture by the transformation parameter, and (e) transmission means for transmitting the compressed picture and the coordinates data.
Patent CA-2495411-C (CA)
Inventor: JIANG PING
IPC: C12N5/06
Filed: 2003-08-18
Granted: 2013-12-10
Abstract: Living cells can be stably modified to emit different colors from the cytoplasm and nucleus, thus permitting analysis of the status of said cells and the effect of agents on said cells either by visual or instrumentally-aided observation. These observations may be made, if desired, in real time.  In addition, rates of proliferation and drug sensitivities can be determined in vitroin real time by the use of cells modified to express a single fluorescent protein and observing fluorescence intensity as a function of time.
Patent CA-2497708-C (CA)
Title: Process for preparing an oil containing one or more long-chain polyunsaturated fatty acids derived from biomass; foodstuff or nutritional, cosmetic or pharmaceutical composition containing it
Inventor: BERTHOLET RAYMOND
IPC: A61K8/02
Filed: 2003-08-07
Granted: 2012-10-09
Abstract: A stable oil containing LC-PUFAs in the form of triacylglycerols, in particular arachidonic acid (ARA), dihomogammalinolenic acid (DHGLA), docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA), may be prepared by direct pressing of one or more biomasses obtained from the culture of a microorganism, especially of a fungus or of a microalga containing the acids ARA, DHGLA, DHA or EPA leading to a first press oil and by bringing a carrier oil entering into the composition of a foodstuff, a cosmetic or pharmaceutical product, into contact with the biomass cake, followed by pressing leading to a second press oil, and then by combining the pressed oils and refining the mixture under controlled conditions.
Patent CA-2498360-C (CA)
Inventor: DEWOLFE ANDREW
IPC: B60R13/02
Filed: 2005-02-24
Granted: 2008-06-03
Abstract: A water and acoustic barrier positionable between a vehicle trim piece and a vehicle body member includes a sheet having a first layer formed of an interpolymer material and a second sheet layer formed of a polyethylene material. A raised rib is formed about at least a portion of a sheet perimeter. The raised rib having an adhesive bead forms a seal between the sheet and the vehicle body member. A raised form positioned adjacent the raised rib but oppositely oriented from the raised rib acts to substantially equalize a sealing pressure along the length of the raised rib. A plurality of apertures define fastener attachment points to connect the barrier to the vehicle trim piece.
Patent CA-2498995-C (CA)
Inventor: MUNJE ARUN
IPC: H04W68/12
Filed: 2005-02-28
Granted: 2009-12-08
Abstract: On présente un procédé et un système de recherche d'un dispositif mobile à l'intersection de zones logiques de deux ou plusieurs sous-systèmes différents, au moyen d'une information indicatrice des zones logiques de chaque sous-système dans lequel le dispositif mobile est susceptible d'être localisé. Dans certains modes de réalisation, seules les cellules qui appartiennent à au moins deux des zones logiques différentes dans lesquelles le dispositif mobile est susceptible d'être localisé sont utilisées pour rechercher le dispositif mobile. Dans certains modes de réalisation, la zone d'intersection est utilisée pour fournir un accès de recherche à un premier réseau sur lequel un mobile n'est pas actif, par l'envoi d'une première recherche de réseau ou d'une demande pour écouter le téléappel sur le second réseau.
Patent CA-2503248-C (CA)
Inventor: JESSE MARY
IPC: H04B1/692
Filed: 1998-02-24
Granted: 2012-02-07
Abstract: A discret multitone stacked-carrier spread spectrum communication method is based on frequency domain spreading including multiplication of a baseband signal by a set of superimposed, or stacked, complex sinusoid carrier waves. In a preferred embodiment, the spreading involves energizing the bins of a large Fast Fourier transform (FFT). This provides a considerable savings in computational complexity for moderate output FFT sizes. Point-to-multipoint and multipoint- to-multipoint (nodeless) network topologies are possible. A code-nulling method is included for interference cancellation and enhanced signal separation by exploiting the spectral diversity of the various sources. The basic method may be extended to include multielement antenna array nulling methods for interference cancellation and enhanced signal separation using spatial separation. Such methods permit directive and retrodirective transmission systems that adapt or can be adapted to the radio environment. Such systems are compatible with bandwidth-on-demand and higher-order modulation formats and use advanced adaptation algorithms. In a specific embodiment the spectral and spatial components of the adaptive weights are calculated in a unified operation based on the mathematical analogy between the spectral and spatial descriptions of the airlink.
Patent CA-2514264-C (CA)
Inventor: JANSSEN WILHELM
IPC: F03D7/02
Filed: 2004-01-23
Granted: 2011-09-13
Abstract: A wind turbine. The wind turbine includes a blade pitch control system to vary a pitch of one or more blades and a turbine controller coupled with the blade pitch control system. A first power source is coupled with the turbine controller and with the blade pitch control system to provide power during a first mode of operation. Uninterruptible power supplies coupled to the turbine controller and with the blade pitch control system to provide power during a second mode of operation. The turbine controller detects a transition from the first mode of operation to the second mode of operation and causes the blade pitch control system to vary the pitch of the one or more blades in response to the transition.
Patent CA-2514407-C (CA)
Title: Thienopyrimidine compounds and use thereof
Inventor: CHO NOBUO
IPC: A61P1/04
Filed: 2004-01-28
Granted: 2012-01-03
Abstract: The present invention provides a compound represented by the formula: (see above formula) wherein R1 is a C1-4 alkyl; R2 is (1) a 5- to 7-membered nitrogen-containing heterocyclic group which may have a substituent selected from the group consisting of (1') a halogen, (2') a hydroxy group, (3) a C1-4 alkyl and (4') a C1-4 alkoxy, (2) a phenyl which may have a substituent selected from the group consisting of (1') a halogen, (2') a C1-4 alkoxy-C1-4 alkyl, (3') a mono-C1-4 alkyl-carbamoyl-C1-4 alkyl, (4) a C1-4 alkoxy and (5') a mono-C1-4 alkylcarbamoyl-C1-4 alkoxy, or the like; R3 is a C1-4 alkyl; R4 is a C1-4 alkoxy, or the like; n is an integer of 1 to 4; or a salt thereof, as a thienopyrimidine compound having gonadotropin-releasing hormone antagonistic activity.
Patent CA-2516472-C (CA)
Title: Manufacturing method for a protective coating for chromium oxide forming substrates subjected to high temperature loading
Inventor: TIETZ FRANK
IPC: C23C10/30
Filed: 2004-01-14
Granted: 2012-10-02
Abstract: As a rule, chromium-oxide forming materials for high temperatures, in particular chromium--based alloys or chromium-rich alloys based on iron (ferritic steel), are used as interconnector materials that are subjected to high temperatures. At SOFC operating temperatures, said material group forms a chromium-based oxidic top coating, which has the advantage of preventing rapid oxidation damage, but also the disadvantage of continuing to react, forming Cr(VI) compounds.  Said volatile compounds react regularly with the cathode material, producing the negative effect of impairing the oxygen reduction. The invention relates to a method for producing a gas-tight protective coating, devoid of chromium, for chromium-oxide forming substrates, such as for example typical interconnector materials, said coating regularly preventing the evaporation of chromium VI compounds during SOFC operating conditions. The protective coating has the general formula: Co3-x-yCuxMnyO4, in which O<x<1.5, 0<y<3 and (x+y) <3
Patent CA-2521389-C (CA)
Inventor: GRIFFITH RICHARD R
IPC: A62B35/04
Filed: 2005-09-28
Granted: 2013-09-03
Abstract: An energy absorber for use in a personal fall arresting system. The absorber contains upper and lower webbings which are each two ply members. The back ply of the upper webbing is mounted adjacent to the face ply of the lower webbing with said webbing being of about equal length and width. Exterior tear elements run back and forth sinusoidally between attachment points on the face ply of the upper webbing and the back ply of the lower webbing. Interior tear elements run back and forth sinusoidally between attachment points on the back ply of the upper webbing and the top ply of the lower webbing.
Patent CA-2521490-C (CA)
Inventor: JONES DAVID HALFORD ASHTON
IPC: C07K16/00
Filed: 2004-05-18
Granted: 2013-07-30
Abstract: The invention provides an immortalized human retina cell, per.C6 TM expressing E1A and E1B proteins of an adenovirus, wherein said cell comprises recombinant nucleic acid encoding an IgM molecule. The invention also provides a method for recombinant production of an IgM molecule, said method comprising culturing a cell according to the invention and expressing said recombinant nucleic acid encoding an IgM.
Patent CA-2521767-C (CA)
Title: Atomizer wicking system
Inventor: MARTENS EDWARD J III
IPC: B05B17/06
Filed: 2004-04-14
Granted: 2010-11-02
Abstract: A replacement reservoir assembly (30) for an atomizing device (20), which uses a vibratable orifice plate (37) for atomizing liquid, includes a container (31), which contains a liquid to be atomized, and an elongated wick (56) having a lower end which is immersed in the liquid within the container (31) and an upper end located above the container (31). The wick (56) includes a dimensionally stable material having capillary passages for drawing liquid out of the container (31) to the upper end of the wick (56), which is outside the container (31). The upper end of the wick (56) has at least one surface that is configured to provide an unobstructed passage to the atmosphere from a region between a top surface of the wick (56) and a facing surface of the vibratable orifice plate (37) when the replacement reservoir is positioned in the atomizing device (20). A wick (56) for use in a replaceable reservoir assembly (30) that contains liquid to be atomized by a vibratory orifice plate (37) and a method of positioning an upper end of a solid, dimensionally stable wick (56) are also disclosed.
Patent CA-2529186-C (CA)
Title: Electronic security system for monitoring and recording activity and data relating to cargo
Inventor: SAJKOWSKY JAMES M
IPC: G06Q10/08
Filed: 2004-06-17
Granted: 2010-04-06
Abstract: A tracking system for identifying contents of a container includes an electromagnetic identification apparatus that provides an electromagnetic signal indicative of a container content data set; a writer for use in encoding the container signal onto the apparatus; a controller for receiving the encoded signal and for storing the signal in a master database storage apparatus; and a reader configured outside the container for communicating with the electromagnetic identification apparatus and for receiving the encoded signal therefrom and corresponding to the container content data signal set. A system for tracking items in an assembly includes an apparatus for receiving electromagnetic identification tag signals; an apparatus for creating a first tier aggregate signature; an apparatus for storing the signature in a master database; and an apparatus for receiving modifying command signals for creating a second tier aggregate signature corresponding to a modified set of electromagnetic identification tags in an augmented assembly.
Patent CA-2529393-C (CA)
Title: Sustained release formulation for venlafaxine hydrochloride
Inventor: KARAVAS EVANGELOS
IPC: A61K31/137
Filed: 2004-07-23
Granted: 2010-08-17
Abstract: The invention provides a sustained release composition that; 1. Is free of initially increased drug delivery that occurs in sustained release systems containing the water soluble drug venlafaxine HCl, known as burst phenomenon, by using a functional core partially or totally coated by a functional coating layer or film. 2. Delivers the drug substance within 24 hours and is therefore suitable for once daily administration of the said drug substance. 3. Exhibits linearity between the strength dosage form and the total mass of the dosage form, by proportional increase of the amounts of the drug substance and the excipients in the formulation. 4. Is possible to be divided in smaller doses, without affecting the release of the drug substance. The invention provides a sustained release capsule formulation containing an appropriate number of functional complex mini tablets comprising of: I . A functional core comprising the active ingredient, especially the water-soluble drug Venlafaxine HCl and appropriate excipients. 2. A functional coating layer or film that reduces the initial surface of the core that is available for the release of the water-soluble drug Venlafaxine HC1t phenomenon