baber/WOPTO huggingface dataset:
Patent CA-2825552-A1 (CA)
Inventor: KIM DAE YOUNG
IPC: A61K39/395
Filed: 2012-01-27
Abstract: The present invention provides a single domain antibody (sdAb) scaffold comprising one or more than one non-canonical disulfide bond in the framework region (FR). The one or more than one non-canonical disulfide bond may be formed between cysteines introduced by mutations in FR2 and FR3. In the case where the sdAb scaffold is a VH, the Cys may be introduced at any one of positions (47-49) and any one of positions (67-71), based on Kabat numbering; in one example, the Cys may be introduced at positions (49) and (69), based on Kabat numbering. In the case where the sdAb scaffold is a VL, the Cys residues may be introduced at any one of positions 46-49 and any one of positions (62-66), based on Kabat numbering; in one example, the Cys residues may be introduced at positions (48 and 64), based on Kabat numbering.
Patent CA-2825642-A1 (CA)
Title: Force sensor and method for testing its reliability
Inventor: BROILLET BERNARD
IPC: G01P15/09
Filed: 2013-08-29
Abstract: The invention relates to a force sensor comprising a transducer with a measuring element operatively connected to a measuring object for generating measuring signals of a force acting on the measuring object, and two transmission channels configured to transmit mutually corresponding signals of said measuring signals independently from one another. The invention also relates to a method for testing the operational reliability of such a force sensor. To allow an easier production of the force sensor and/or to provide the force sensor with an improved operational characteristics, the invention suggests that said transmission channels are connected in parallel to the same transducer such that the transmitted signals at the output of each transmission channel can be verified. In an according testing method, a test signal is evaluated in a transmission channel in which the test signal has been injected and in another transmission channel in which the test signal has not been injected. In another testing method, the transmitted signals are compared, wherein the result of the comparison is used to assess the correctness of the transmitted signals.
Patent CA-2826569-A1 (CA)
Inventor: BEDELL RAYMOND
IPC: A61M25/10
Filed: 2012-02-02
Abstract: A steerable catheter includes a body portion, a flexible catheter body with a proximal end and a distal tip and a continuous steering wire passing through the flexible body from the proximal end to the distal tip and turning back through the flexible body from the distal tip to the proximal end.
Patent CA-2828760-A1 (CA)
Title: System and method for selectively transcoding signal from one format to one of plurality of formats
Inventor: SCHAFFER MARK L
IPC: H04N21/4402
Filed: 2011-10-27
Abstract: A device is provided for use with an input signal and a selecting signal. The input signal has a first format, and the selecting signal has a first state and a second state. The device comprises a receiving portion and a transcoder portion. The receiving portion can receive the input signal and output a received signal. The transcoder portion is arranged to receive the selecting signal and can output a first transcoded signal when the selecting signal is in the first state and can output a second transcoded signal when the selecting signal is in the second state. The first transcoded signal is based on the received signal and is in a second format. The second transcoded signal is based on the received signal and is in a third format, wherein the first format is different from the second format, the first format is different from the third format and the second format is different from the third format.
Patent CA-2829309-A1 (CA)
Title: Procede et appareil d'initialisation d'un outil de prospection de puits de forage par l'intermediaire d'une source de reference distante
Inventor: WESTON JOHN LIONEL
IPC: E21B19/00
Filed: 2012-02-28
Abstract: La présente invention concerne un procédé et un appareil permettant de déterminer l'orientation d'un outil de prospection de puits de forage à une première position par rapport à une direction de référence. Au moins un premier signal indique une orientation d'un système de référence directionnelle par rapport à la direction de référence. Le système de référence directionnelle est positionné à une seconde position espacée par rapport à la première position. Au moins un second signal indique une orientation relative de l'outil de prospection de puits de forage par rapport au système de référence directionnelle. L'orientation de l'outil de prospection de puits de forage à la première position est déterminée en réponse, au moins partiellement, au(x) premier(s) signal(aux) et au(x) second(s) signal(aux).
Patent CA-2836792-A1 (CA)
Inventor: KUMAR ANIL
IPC: C09K19/00
Filed: 2012-06-01
Abstract: Provided are photochromic articles that include a substrate, a primer layer that includes a first photochromic compound, and a photochromic-dichroic layer over the primer layer that includes a photochromic-dichroic compound. The first photochromic compound and the photochromic-dichroic compound each are selected such that the photochromic-dichroic compound has an absorbance of less than or equal to 0.1 at the wavelength of peak absorbance of the underlying first photochromic compound. The present invention also relates to such photochromic articles that further include a topcoat layer over the photochromic-dichroic layer. The topcoat layer can include a second photochromic compound that has an absorbance of less than 0.1 at the wavelength of peak absorbance of the underlying photochromic-dichroic compound. The photochromic articles provide, for example, a combination of linear polarizing properties, and reduced percent transmittance when in a colored or darkened state, such as when exposed to actinic light.
Patent CA-2838767-A1 (CA)
Title: Methode de prediction de la reponse a un traitement avec un agent bloquant her2
Inventor: PAGES GILLES
IPC: G01N33/574
Filed: 2012-06-07
Abstract: L'invention concerne notamment une méthode in vitro ou ex vivo de prédiction de la réponse d'un sujet à un traitement avec au moins un agent bloquant HER2, ladite méthode comprenant les étapes de : i) identification du nucléotide au niveau du site polymorphe rs3746083, pour au moins un allèle, en particulier les deux allèles du gène codant la protéine tristétraproline, dans un échantillon biologique dudit sujet; et/ou ii) détermination du taux de protéine tristétraproline, dans un échantillon biologique dudit sujet; dans laquelle ledit sujet est atteint d'un cancer HER2 -positif.
Patent CA-2840332-A1 (CA)
Title: Microbiocidal heterocycles
Inventor: SULZER-MOSSE SARAH
IPC: C07D401/14
Filed: 2012-06-27
Abstract: The present invention relates to heterocyclic compounds of formula I which have microbiocidal activity, in particular fungicidal activity as well as methods of using the compounds of formula (I) to control microbes: wherein A is x-C(R10R11)-C(=O)-, x-C(R12R13)-C(=S)-, x-O-C(=O)-, x-O-C(=S)-, x-N(R14)-C(=O)-, x-N(R15)-C(=S)-, x-C(R16R17)-SO2- or x-N=C(R30)-,, in each case x indicates the bond that is connected to R1; T is CR18 or N; Y1, Y2, Y3, and Y4 are independently CR19 or N; Q is O or S; n is 1 or 2; p is 1 or 2, providing that when n is 2, p is 1. R1 is (formula A) R2, R3, R4, R5, R6, R7, R10, R11, R12, R13, R16, R17, R18,R19 and R30 each independently are hydrogen, halogen, cyano, C1-C4alkyl, or C1-C4haloalkyl; R8, R14 and R15 each independently are hydrogen or C1-C4alkyl; and R9 is phenyl, benzyl or group (a), wherein the phenyl, benzyl and group (a) are each optionally substituted with 1 to 3 substituents independently selected from C1-C4 alkyl, C1-C4 haloalkyi, halogen, cyano, hydroxy and amino; or a salt or a N-oxide thereof.
Patent CA-2841252-A1 (CA)
Inventor: LEE JU YOUNG
IPC: C07D487/04
Filed: 2012-07-13
Abstract: The present invention provides a novel 2-pyridyl substituted imidazole derivative, or a pharmaceutically acceptable salt or solvate thereof, which selectively inhibits the transforming growth factor-ß (TGF-ß) type I receptor (ALK5) and/or the activin type I receptor (ALK4); a pharmaceutical composition comprising same as an active ingredient; and a use of the 2-pyridyl substituted imidazole derivative for the manufacture of a medicament for preventing or treating a disease mediated by ALK5 and/or ALK4 receptors in a mammal.
Patent CA-2841598-A1 (CA)
Inventor: STAMP CHRISTOPHER
IPC: H04L12/16
Filed: 2014-02-03
Abstract: The described embodiments relate to systems, methods and computer readable media for bidding on service requests, that involves receiving a service request, wherein the service request indicates a user identifier and an item to be serviced; generating a bid request corresponding to the service request; receiving a plurality of bids, wherein each bid indicates a service provider identifier for a corresponding service provider and a cost for servicing the item; transmitting the plurality of bids; and receiving a selected bid of the plurality of bids.
Patent CA-2843737-A1 (CA)
Inventor: STEELMAN RONALD S
IPC: C08J7/046
Filed: 2012-07-31
Abstract: The present application is directed to articles useful as graphic films. Specifically, the present application is directed to a multilayer film, at least one layer of the multilayer film comprising a polymer blend comprising a thermoplastic polyurethane and a cellulose ester. In some embodiments, a second layer of the multilayer film comprises thermoplastic polyurethane and the cellulose ester. In some embodiments, a second layer of the multilayer film comprises a material different from the polymer blend.
Patent CA-2843920-A1 (CA)
Title: Fluid valves having multiple fluid flow control members
Inventor: ANAGNOS RICHARD JAMES
IPC: F16K1/44
Filed: 2012-08-07
Abstract: A valve trim apparatus includes a first flow control member (218) disposed in a passageway (204) of a fluid valve (200), the first flow control member (218) moves relative to a first orifice (212) of the passageway (204) to provide a first fluid flow characteristic through the passageway (204). A second flow control member (224) is disposed within the passageway (204) and is to move relative to a second orifice(216) of the passageway (204) defined by the first flow control member (218) when the first flow control member (218) is in sealing engagement with the first orifice (212) to provide a second fluid flow characteristic through the passageway (204). The first fluid flow characteristic is different than the second fluid flow characteristic.
Patent CA-2845959-A1 (CA)
Inventor: GOEDECKE LYNDON KARL
IPC: G01N27/62
Filed: 2014-03-13
Abstract: An apparatus for detecting constituents in a sample includes a casing and an ionization chamber defined by the casing. The apparatus also includes an ion collector positioned downstream of the ionization chamber. The apparatus further includes a spectral analysis device coupled to the ion collector. The spectral analysis device is configured to generate a detection spectrum representative of ions collected at the ion collector. The detection spectrum includes an analyte peak portion and a peak tailing portion. The apparatus also includes a control system that is configured to generate a first pulse having a first polarity to initiate a discharge of stored ions from the ionization chamber. The control system is also configured to generate a second pulse substantially immediately after the first pulse. The second pulse has a second polarity opposite the first polarity and is configured to reduce the peak tailing portion.
Patent CA-2846461-A1 (CA)
Title: Layered manufacturing of free-form multi-material micro-components
Inventor: AKLINT THORBJORN
IPC: B29C67/00
Filed: 2012-08-22
Abstract: Method for additive layer manufacturing of objects comprised of more than one material with free-form capability for all included materials. The method can for example be used for producing packaging for Microsystems where the ceramic acts as an insulator and the secondary material is used to produce electrical or optical 3D conductor lines or electrical or optical 3D vias. The fine powder used in this method enables it to be used for building components with small feature size and demand for high precision. Other intended uses for this method is to build small mechanical precision parts or grinding tools, dental objects or medical implants.
Patent CA-2849669-A1 (CA)
Title: Novel serine protease variants
Inventor: BARTH STEFAN
IPC: C12N9/64
Filed: 2012-09-21
Abstract: The present disclosure provides novel variants of enzymes exhibiting serine protease activity; nucleic acid molecules encoding said proteases, vectors, host cells containing the nucleic acids and methods for preparation and producing such enzymes; compositions and complexes comprising at least one of the proteases; and methods for using such enzymes as a part of an immunoprotease, in particular for the treatment of cancer.
Patent CA-2850284-A1 (CA)
Title: Floor covering
Inventor: KROGER MARIO
IPC: E04F15/16
Filed: 2012-09-21
Abstract: The invention relates to a floor covering (1) comprising a web- or plate-shaped base material (2) made from an elastomer material, wherein the base material (2) is provided with mineral decorative particles (3), and wherein the density of the mineral decorative particles (3) is not greater than 3 kg/dm3.
Patent CA-2851981-A1 (CA)
Inventor: YOUNG JOHN D
IPC: A61K33/00
Filed: 2014-05-16
Abstract: An oxygenated oil ointment is made, for example, by stirring or agitating plant-based oil while injecting a gas into the plant-based oil, resulting in a coagulated ointment that is beneficial for topical application. In one example, the plant-based oil is olive oil and the gas includes ozone, which is known to kill pathogens. Once the ozone coagulates with the olive oil, the resulting ointment retains the ozone gas until the ointment is applied on the skin for treatment of, for example, cuts and sores.  In some ointments, the pH of the plant-based oil is increased by adding one or more alkaline materials to the plant-based oil before coagulation occurs. This increase in alkalinity improves the ointment's ability to give off ozone and oxygen.
Patent CA-2852787-A1 (CA)
Inventor: LAHTINEN MARKKU
IPC: F27D3/18
Filed: 2011-11-29
Abstract: The invention relates to a method for controlling suspension in a suspension smelting furnace, to a suspension smelting furnace, and to a concentrate burner. The method comprises feeding additionally to pulverous solid matter and additionally to reaction gas reducing agent into the suspension smelting furnace, wherein reducing agent is fed in the form of a concentrated stream of reducing agent through the suspension in the reaction shaft onto the surface of the melt to form a reducing zone containing reducing agent within the collection zone of the melt.
Patent CA-2858501-A1 (CA)
Title: Bioabsorbable composite material containing pldga and a ceramic additiveand its use
Inventor: HUTTUNEN MIKKO
IPC: A61L31/14
Filed: 2012-12-21
Abstract: The present invention relates to bioabsorbable polymer composite materials, which contain a polymer matrix component composition including one or more multimonomer-polymers and one or more biocompatible additives, as well as a process for their manufacture. Further, the invention relates to surgical devices, such as pins, screws, plates, tacks, bolts, intramedullary nails, suture anchors, wedges, wires, filaments, sutures or staples, containing said composite, and a process for their manufacture.
Patent CA-2858571-A1 (CA)
Inventor: RUNYON SCOTT
IPC: A61P25/00
Filed: 2012-12-06
Abstract: Neuropeptide S receptor antagonists are provided that bind in functional assays to neuropeptide S receptors; methods are provided for use of these antagonists in treatment of conditions or disease states that are ameliorated by blocking of the neuropeptide S receptor, including substance abuse and substance abuse relapse; and for use of neuropeptide S receptor antagonists in the manufacture of therapeutics and pro-drugs for therapeutics useful in disease states and conditions sensitive to binding of the neuropeptide S receptor.
Patent CA-2860910-A1 (CA)
Title: Fluid additive delivery system with flow meter
Inventor: HAMMONDS CARL L
IPC: G01F3/00
Filed: 2013-01-03
Abstract: A system for delivering an additive to a flowing fluid wherein the system is in whole or in part powered by the flow of the fluid is provided. The fluid-additive delivery system includes a fluid motor, a speed sensor, an electricity generation and storage system, a clutch, an additive pump, and a flow meter, where the fluid motor and the flow meter are in fluid communication with a piping of the fluid to which the fluid additive is to be added. The flow meter provides high resolution with infinite turndown, providing a flow meter which may be used in low flow situations and with fluid additives. The flow rate of an additive fluid is determined in real time with high resolution by providing a novel reciprocating positive-displacement flow meter using magnetically coupled components and a transducer to identify the flow rate of the fluid.
Patent CA-2861242-A1 (CA)
Title: System and method for online inspection of turbines including aspheric lens
Inventor: BALEINE ERWAN
IPC: G02B23/24
Filed: 2013-01-24
Abstract: Optical camera systems for nondestructive internal inspection of online, operating power generation turbines, including gas turbine combustor and turbine sections that are at high operating temperatures in the range of over 600°C (1112°F) and which include combustion gas contaminants. The inspection system includes one or more aspheric lenses capable of withstanding continuous operating temperatures above 600°C. The aspheric lenses, alone or in combination with spherical lenses, establish a wider field of view, and require fewer lenses in combination than lens mounts incorporating only spherical lenses. A cooling system incorporated in the inspection system facilitates continuous operation and inhibits lens external surface fouling from combustion gasses.
Patent CA-2865251-A1 (CA)
Inventor: RENTSCH SAMUEL
IPC: C09C1/02
Filed: 2013-03-21
Abstract: The present invention relates to an aqueous calcium carbonate containing composition, to methods for producing such aqueous calcium carbonate containing compositions and to the use of the aqueous calcium carbonate containing composition in paper, paper coating, plastics and/or paint applications and as filler in paper.
Patent CA-2865697-A1 (CA)
Inventor: ARENSMEIER JEFFREY N
IPC: G06Q50/06
Filed: 2013-02-28
Abstract: A method of operating a heating, ventilation, or air conditioning (HVAC) monitor-ing service is described. The method includes: providing a local device for instal-lation in an HVAC system of a residential or commercial building; periodically re-ceiving data from the local device across a wide area network, wherein the re-ceived data includes electrical sensor data including at least one of current or power; and storing the received data. The method further includes: analyzing the stored data to selectively identify problems and selectively predict faults of the HVAC system; receiving a subscription fee corresponding to the building, the subscription fee applying to a calendar period; and during the calendar period, providing information on the identified problems and the predicted faults to a customer corresponding to the building.
Patent CA-2868092-A1 (CA)
Title: Stretched and foamed plastic formed body having appearance of a metal color
Inventor: AKUZAWA NORIO
IPC: B29C49/06
Filed: 2013-03-04
Abstract: Provided is a foam molded article for a bottle or the like that has a metallic appearance, specifically gold or silver, without the use of expensive glossy pigments such as metal powder pigments or flake pigments. A foam region containing foam cells (1) is formed in at least part of the stretched foam plastic molded article, the foam cells have a flat shape with a maximum thickness of 30 µm or less and an average aspect ratio of at least 4 as seen in vertical cross-section along the direction of maximum drawing of the molded article. A non-foam plastic surface layer (5), in which the foam cells are not distributed, is formed on the outer surface of the foam region. Furthermore, this molded article is characterized in that non-glossy pigments differing from glossy pigments such as flake pigments are mixed into the molded article as coloring, and the foam region of the molded article takes on a metallic color.
Patent CA-2870791-A1 (CA)
Inventor: SCORSIN MARCIO
IPC: A61F2/24
Filed: 2013-04-26
Abstract: Heart valve prosthesis, comprising a ring-shaped supporting structure (3) to be anchored at the valve annulus, and a valve leaflet (5) supported by the supporting structure. The supporting structure comprises a support wall portion (31), at which a root end (51) of the valve leaflet is connected, and a complementary wall portion (32) opposite the support wall portion, which supports a coaptation surface (33) adapted to be sealingly engaged by a free end (52) of the valve leaflet (5), and extending in a direction parallel to the direction of movement of the free end (52) of the valve leaflet (5) at the coaptation surface (33). The free end of the valve leaflet (5) is connected to the support wall portion or to the complementary wall portion by means of a traction member (55), dimensioned in such a way that the free end (52) of the valve leaflet (5) is stopped at the coaptation surface.
Patent CA-2871403-A1 (CA)
Inventor: JUDY VICTORIA
IPC: G08G5/00
Filed: 2014-11-17
Abstract: An alerting system and method for producing tactical views of datalink messages is provided. The system comprises a datalink application processor configured to receive and decode an uplink datalink message. The datalink application processor includes a datalink message manager. The system also includes a control processor in operative communication with the datalink application processor and configured to communicate with the datalink message manager. A display unit is in operative communication with the control processor and is configured to show the uplink datalink message. The control processor is configured receive message data from the datalink message manager and output the message data to the display unit to generate an annunciation of the datalink message. The datalink message manager is configured to output display data for generating the datalink message in full based on a single forward field of view interaction by a user with the display unit.
Patent CA-2871683-A1 (CA)
Inventor: CZERNY CLAUS-PETER
IPC: C12Q1/68
Filed: 2013-04-26
Abstract: The invention relates to a method for specifically detecting and optionally for quantifying Mycobacterium avium ssp. paratuberculosis (MAP) in a sample of an individual. According to the method according to the invention, for this purpose the detection of the presence of the IS900 region in a sample is performed by means a nucleic acid amplification and specific oligonucleotides. In a further aspect, the invention relates to a test kit for specifically detecting MAP in a sample by means of amplification methods. Finally, the invention relates to specific oligonucleotides that are suitable for specifically detecting MAP.
Patent CA-2873561-A1 (CA)
Inventor: KAX HENRIK
IPC: A45F3/04
Filed: 2014-12-08
Abstract: A locking mechanism for a shoulder strap of a backpack is disclosed which comprises guiding means, retaining means, and engaging means, wherein the engaging means is rotatable about an axis (A) and slidably guided along the guiding means, wherein in a first rotational position the engaging means engages the retaining means so that a sliding movement of the engaging means along the guiding means is restricted, and wherein in a second rotational position the engaging means disengages the retaining means so that a sliding movement of the engaging means along the guiding means is enabled.
Patent CA-2873734-A1 (CA)
Inventor: FAIVRE-CHAUVET ALAIN
IPC: A61P35/00
Filed: 2013-05-14
Abstract: The present invention concerns radioactive rhodium complexes, their preparation methods, and their use for the radiolabelling of biomolecules, especially monoclonal antibodies.