baber/WOPTO huggingface dataset:
Patent AU-2020395318-A1 (AU)
Title: Methods related to toxicity and response associated with cell therapy for treating B cell malignancies
Inventor: DUBOVSKY JASON A
IPC: A61K39/00
Filed: 2020-12-04
Abstract: Provided are methods for determining the risk of toxicity (e.g., neurotoxicity) and/or the likelihood of response to a cell therapy. In some aspects, the methods generally involve assessing parameters or biomarkers (e.g., blood analytes) that are associated with toxicity and/or response. In some aspects, the methods relate to adoptive cell therapy involving the administration of doses of cells for treating subjects with certain B cell malignancies, such as chronic lymphocytic leukemia (CLL), such as relapsed or refractory CLL, or small lymphocytic lymphoma (SLL). The cells for the adoptive cell therapy generally express recombinant receptors such as chimeric antigen receptors (CARs). In some aspects, the methods can be used to identify or select subjects for treatment, for example, with a cell therapy.
Patent AU-2020398660-A1 (AU)
Title: Machine learning techniques for gene expression analysis
Inventor: ANTYSHEVA ZOIA
IPC: G16B25/10
Filed: 2020-12-05
Abstract: Techniques for determining one or more characteristics of a biological sample using rankings of gene expression levels in expression data obtained using one or more sequencing platforms is described. The techniques may include obtaining expression data for a biological sample of a subject. The techniques further include ranking genes in a set of genes based on their expression levels in the expression data to obtain a gene ranking and determining using the gene ranking and a statistical model, one or more characteristics of the biological sample.
Patent AU-2020417722-A1 (AU)
Title: Dynamically rendered interface elements during online chat sessions
Inventor: BELCHER BERRY
IPC: G06Q30/00
Filed: 2020-12-16
Abstract: There are provided systems and methods for dynamically rendered interface elements during online chat sessions. A user may engage in online communications with another user, such as a communication session between a customer and a customer representative or agent of a merchant. During this communication session, the agent may navigate to particular data on the agent's device, which may be desirable to provide to the customer. For example, the agent may view a particular item of interest to the customer. An application programming interface of the merchant may detect one or more actions or calls associated with this data and may dynamically provide an interface element to transmit data displayed on the agent's device to the customer's device during the communication session. The customer may view a dynamically rendered interface element that allows for processing data during the communication session with the agent.
Patent AU-2020450373-A1 (AU)
Title: Stem for artificial joint
Inventor: NODA IWAO
IPC: A61F2/32
Filed: 2020-05-29
Abstract: The stem for an artificial joint according to the present disclosure comprises a base extending vertically in a case in which the side near the human body when the artificial joint is used is in the upward direction, and a coating film that is arranged on a portion of the base and that includes a calcium-phosphate-based material and an antimicrobial material. A boundary line on the base defined by the presence or absence of the coating film includes a first boundary line positioned on the downward side of the base with respect to the coating film. The first boundary line is positioned so as to intersect the vertical direction. The portion of the first boundary line along the vertical direction is smaller than the portion thereof along the width direction of the base.
Patent WO-2021189097-A1 (WO)
Inventor: MARTIN TIMOTHY SEAN CHRISTOPHER
IPC: B62J17/00
Filed: 2021-03-10
Abstract: An apparatus for reducing drag and wake formation behind moving vehicles such as road transport vehicles, motor cycles and bicycles including electric bicycles comprising one or more vents, each of those vents having a proximal end and a distal end, both ends being open and positioned and aligned longitudinally in the direction of travel in such a way as to addressing wake and boundary layer formation of a moving vehicle, said vents, positioned spaced from turbulent rear surfaces of the vehicle and affixed to the main body of the vehicle by one or more connecting members.
Patent WO-2021258147-A1 (WO)
Inventor: NGUYEN ANH TUAN
IPC: C08L79/02
Filed: 2021-06-24
Abstract: Decribed herein is a method of preparing a thermoresponsive polymer biomacromolecule conjugate, the method comprising: preparing by living cationic ring opening polymerisation a thermoresponsive polymer selected from polyoxazoline, polyoxazine, or copolymer thereof, the so-formed thermoresponsive polymer having a living cation; and reacting the living cation with a nucleophilic functional group selected from carboxylate, amino, sulfate, sulfonate, phosphate, phosphonate and thiol of a biomacromolecule to conjugate the thermoresponsive polymer to the biomacromolecule; wherein in an aqueous liquid the so-formed thermoresponsive polymer biomacromolecule conjugate exhibits a gelation temperature and forms a hydrogel in that liquid above that gelation temperature.
Patent AU-2021201719-A1 (AU)
Title: Delayed gelation of polymers
Inventor: GUAN HUILI
IPC: C09K8/60
Filed: 2021-03-18
Abstract: The disclosure is directed to methods and compositions delaying the gelation of polymers in water 
flooding by sequentially or co-injecting a carboxylate-containing polymer solution, a gel-delaying 
5 polymer, and gelation agent into a hydrocarbon reservoir. Delays of weeks are observed.
Patent AU-2021202481-A1 (AU)
Title: Compounds and matrices for use in bone growth and repair
Inventor: CASHMAN JOHN R
IPC: A61K31/4706
Filed: 2021-04-22
Abstract: Compositions of small molecules, matrices, and isolated cells including methods 
of preparation, and methods for differentiation, trans-differentiation, and proliferation of 
animal cells into the osteoblast cell lineage were described. Examples of osteogenic 
materials that were administered to cells or co-cultured with cells are represented by 
compounds of Formula 1l, IV, and VI independently or preferably in combination with a 
matrix to afford bone cells. Small molecule-stimulated cells were also combined with a 
matrix, placed with a cellular adhesive or material carrier and implanted to a site in an 
animal for bone repair. Matrix pretreated with compounds of Formula 1l, IV, and VI were 
also used to cause cells to migrate to the matrix that is of use for therapeutic purposes.
Patent AU-2021203878-A1 (AU)
Title: Animal enclosure
Inventor: HARFOUCHE GABRIEL
IPC: A01K1/03
Filed: 2021-06-10
Abstract: An animal enclosure comprises a cage having an opening in a side of the cage and a 
base disposed underneath the cage, wherein one or more openings are provided in a 
side of the base for receiving lifting equipment. A container is disposed inside of the 
cage, the container comprising an internal cavity and an aperture provided in a side of 
the container, wherein the aperture is aligned with the opening of the cage to provide 
an entryway into the internal cavity.
Patent AU-2021231219-A1 (AU)
Title: Monitoring device, monitoring arrangement and monitoring method for monitoring a screw joint of an object
Inventor: WEST RICK
IPC: F16B31/02
Filed: 2021-03-03
Abstract: The invention relates to a monitoring device (10) for monitoring a screw joint of an object, comprising a base plate (11) to be attached to the object and a top plate (12) to be attached to one part of the screw joint, wherein the base plate (11) and the top plate (12) are positioned parallel to and on top of each other and wherein both plates (11, 12) each comprise at least one electrode (112a-p, 122) that capacitively interact with each other. The monitoring device (10) is characterized in that the electrodes (112a-p, 122) are shaped and positioned such that at least one electrode (122) of one of the plates (11, 12) interacts with at least two different electrodes (112a-p) of the other one of the plates (11, 12) depending on the rotational position of the plates (11, 12) relative to each other. The invention further relates to a monitoring arrangement having at least one monitoring device (10) of this kind and to a monitoring method.
Patent AU-2021236437-A1 (AU)
Title: Rationally-designed single-chain meganucleases with non-palindromic recognition sequences
Inventor: SMITH JAMES JEFFERSON
IPC: C12N9/22
Filed: 2021-09-20
Abstract: : 
Disclosed are rationally-designed, non-naturally-occurring meganucleases in which a pair of 
enzyme subunits having specificity for different recognition sequence half-sites arejoined into 
a single polypeptide to form a functional heterodimer with a non-palindromic recognition 
sequence. The invention also relates to methods of producing such meganucleases, and 
methods of producing recombinant nucleic acids and organisms using such meganucleases.
Patent AU-2021238895-A1 (AU)
Title: Building element
Inventor: GARCIA HUGO GUSTAVO
IPC: E04C3/07
Filed: 2021-03-16
Abstract: A building element (10) for a structural system, the building element (10) comprising: a first elongate beam (20) formed to have a base (22) and two sides (24, 26), the two sides (24, 26) extending away from the base (22) to generally define a C-shape profile; a second elongate beam (30) having a C-shape profile substantially the same as the first beam (20); and a third elongate beam (40) having a C-shape profile substantially the same as the first beam (20); wherein, the second (30) and third beams (40) are arranged such that an opening (28, 38, 48) of the C-shape profile of each beam are in an opposing facing relationship, said second and third elongate beams (30, 40) being attached to the first beam (20).
Patent AU-2021245189-A1 (AU)
Title: Vacuum adiabatic body and refrigerator
Inventor: JUNG WONYEONG
IPC: F25D19/00
Filed: 2021-10-07
Abstract: A vacuum adiabatic body comprising: a plate: a seal that seals an edge of the plate to provide an 
inner space in a vacuum state; a side frame defining at least one portion of a wall of the inner 
space; at least one of a shielding part disposed outside of the inner space, the shielding part being 
provided as an adiabatic structure; and an addition mounting part disposed outside of the inner 
space, the addition mounting part being defined as a component that provides a place where an 
addition is mounted, wherein the vacuum adiabatic body further includes a main portion and a 
side portion, the side portion defining an edge portion of the vacuum adiabatic body.  
18118738_1 (GHMatters) P43844AU02
Patent AU-2021246903-A1 (AU)
Title: Assays for the detection of SARS-CoV-2
Inventor: BRAMBATI CHIARA
IPC: C12N1/00
Filed: 2021-03-31
Abstract: The present invention is directed to methods for assaying for the presence of SARS-CoV-2 in a sample, including a clinical sample, and to oligonucleotides, reagents, and kits useful in such assays. In particular, the present invention is directed to such assays that are rapid, accurate and specific for the detection of SARS-CoV-2 using labeled oligonucleotides hybridizing to the ORFlab and/or S gene.
Patent AU-2021250925-A1 (AU)
Title: Compositions containing Ibrutinib
Inventor: GOLE DILIP
IPC: A61K47/38
Filed: 2021-10-14
Abstract: Discussed herein are pharmaceutical compositions containing Ibrutinib and processes for 
preparing them. The compositions may be utilized in the treatment of a variety of conditions 
including, without limitation, B-cell proliferative disorders such as non-Hodgkin lymphoma 
(diffuse large B cell lymphoma, follicular lymphoma, mantle cell lymphoma or burkitt 
lymphoma), Waldenstrom macroglobulinemia, plasma cell myeloma, chronic lymphocytic 
leukemia, lymphoma, or leukemia. These compositions are designed for oral ingestion. The 
compositions are contained within a capsule such as a standard or sprinkle or in a liquid 
formulation such as a suspension. In one embodiment, the pharmaceutical composition contains 
Ibrutinib, a salt, prodmg, or metabolite thereof, microcrystalline cellulose, croscamieliose 
sodium, sodium lauryi sulfate, and magnesium stearate. In another embodiment, the 
pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, 
microcrystalline cellulose, carboxymethylcellulose sodium, hydroxypropylmethylcellulose, 
citric acid monohydrate, disodium hy drogen phosphate, sucralose, sodium methyl 
parahydroxybenzoate, sodium ethyl parahydroxybenzoate, concentrated hydrochloric acid, 
sodium hydroxide, and water.
Patent AU-2021254514-A1 (AU)
Title: Casino system
Inventor: SHIGETA YASUSHI
IPC: G06K7/10
Filed: 2021-10-18
Abstract: A casino system in a casino using a gaming chip (72) to which 
an RFID tag (721) storing identification information is attached, 
comprising a registration device (325) for registering the 
identification information of the gaming chip to be used in the 
casino, and a database (326) for storing a list of the identification 
information registered by the registration device (325). The list 
includes status information that indicates whether or not the gaming 
chip (72) is usable, and the registration device (325) makes the 
status information usable for the gaming chip (72) that has already 
been registered.  
113
REID TAG 
MANUFACTURING - 100 
FACTORY 
72 Y200 
MANUFACTURING- 
300 [ 73 
CASINO
3 0 1 
SECURITY AREA 
WAREHOUSE >PROCEDURE 
31 33 CASHIER BANK 
302 FLOORAREA 35 
36 3574 
TABLE -- > PIT 
75--- 36 74 
TABLE TAB LEI 36 
74 36 35 
TABLE PIT 
74 74 367 75 '' 36 
74-lj 
74-ApoTYABLE TABLE 
74 75 
38~ GATE 
FIG.1
Patent AU-2021264426-A1 (AU)
Title: Method and system for attaching articles to a carrier
Inventor: FORD COLIN P
IPC: B65D71/18
Filed: 2021-04-26
Abstract: A method of at least partially forming packages. The method comprises moving a blank and a plurality of articles in a downstream direction through a clipping station. The blank can comprise at least a first attachment panel, a second attachment panel, and a keel portion extending from the first attachment panel to the second attachment panel. The method further can comprise forming a clipped assembly by clipping the first attachment panel and the second attachment panel of the blank to respective articles of the plurality of articles during the moving the blank and the plurality of articles through the clipping station and forming a keel by moving articles of the plurality of articles toward one another and folding the keel portion of the blank between the articles as the clipped assembly is moved in the downstream direction.
Patent AU-2021279275-A1 (AU)
Title: Conveyor belt
Inventor: KOLKMAN ARD
IPC: C08L67/00
Filed: 2021-05-27
Abstract: This invention relates to a conveyor belt comprising a composition comprising a) a (co)polyester A comprising hard segments comprising a polyester and having a melting temperature T
Patent AU-2021291445-A1 (AU)
Title: Tubular end protector
Inventor: SKJEVIK GEIR
IPC: F16L57/00
Filed: 2021-06-21
Abstract: A protector is proposed for an end of an elongate member, such as an end of a pipe or tube. The protector comprises a rigid portion which has a body portion for insertion into a cavity defined by an end portion of the elongate member, and a cover portion extending from the body portion. The protector further comprises a flexible portion provided on an outer surface of the body portion. The flexible portion comprises one or more resilient members. When the body portion is received within the cavity of the elongate member, the resilient members engage the inner surface of the cavity, and the cover portion covers an end surface of the elongate member.
Patent AU-2021295599-A1 (AU)
Title: Helmet
Inventor: POMERING AMY LOUISE
IPC: A42B3/14
Filed: 2021-06-25
Abstract: A helmet (1), comprising an outer shell (2); a head mount (20), configured to be mounted on the top of the head of a wearer of the helmet; wherein the head mount is suspended within the outer shell such that, in use, an air gap (21) is provided between head mount and the outer shell; the helmet further comprises a head engagement device (40) that is mounted on a surface of the head mount, that is configured to face the head of a wearer of the helmet, such that the head engagement device can move relative to the head mount; and a low friction interface is provided between the head mount and the head engagement device.
Patent AU-2021302056-A1 (AU)
Title: Crystalline form of heterocyclic compound, preparation method therefor and application thereof
Inventor: WANG LIANG
IPC: A61P11/14
Filed: 2021-06-24
Abstract: Provided are a crystalline form of a compound represented by formula A, the crystalline form being crystalline form I, crystalline form II, crystalline form III, crystalline form IV, crystalline form V, crystalline form VI, crystalline form VII, crystalline form VIII or crystalline form IX, a preparation method therefor, a composition thereof, and an application thereof in the preparation of a P2X3 receptor antagonist or an application thereof in the preparation of drugs preventing and/or treating pains, urinary tract illness or respiratory system illness. The compound has high P2X3 antagonist activity, and has good selectivity, low toxicity, good metabolic stability and little taste influence.
Patent AU-2021315748-A1 (AU)
Title: System and method for the biodegradation of bio-based polymers in soils and landfills
Inventor: QUIRK STEPHEN
IPC: C12N11/08
Filed: 2021-07-07
Abstract: A process and system are disclosed for increasing the rate of degradation of biopolymers in a solid waste depository, such as a landfill. A microorganism product, which can be an encapsulated product, is combined with the waste materials. The product contains one or more microorganisms that are designed to secrete an enzyme that degrades the biopolymer, which can be a polyhydroxybutyrate polymer. The microorganism can naturally secrete the enzyme or can be genetically modified to secrete the enzyme. The microorganisms or bacteria incorporated into the product are particularly selected in order to thrive in a particular environmental condition where the solid waste is located.
Patent AU-2021331064-A1 (AU)
Title: Human cytomegalovirus vaccine
Inventor: KRAMARCZYK JACK F
IPC: A61K31/7115
Filed: 2021-08-25
Abstract: Aspects of the disclosure relate to methods for producing an antigen- specific immune response to human cytomegalovirus (hCMV) in a subject by administering mRNA vaccines.
Patent AU-2021336977-A1 (AU)
Title: Quinoline cGAS antagonist compounds
Inventor: QIU JIAN
IPC: A61P25/28
Filed: 2021-09-03
Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.
Patent AU-2021353752-A1 (AU)
Title: Cyclic sulfone additives for lithium ion batteries
Inventor: MOGANTY SURYA
IPC: H01M4/131
Filed: 2021-03-31
Abstract: Cyclic sulfone organic compounds and an electrolyte containing the cyclic sulfone organic compounds suitable for use in electrochemical energy storage devices useful for reducing battery resistance, increasing cycle life, and improving high-temperature performance are disclosed.
Patent AU-2021378522-A1 (AU)
Title: Abrasive material, accessories for a tool containing such abrasive material and method of manufacturing such abrasive material
Inventor: MARIS JOHAN JOZEF F
IPC: B24D3/00
Filed: 2021-11-15
Abstract: Abrasive material, characterised in that the abrasive material (1) includes a double layer of fabric (2) with connection (3) cut in the middle to form hairs (4) or fibres (4) on the first side (5) of the abrasive material (1), where the hairs (4) are post-treated so that the shape of the hairs (4) is permanently changed, and where the hairs (4) are equipped with abrasive particles (8).
Patent AU-2021381981-A1 (AU)
Title: Biomass pyrolysis integrated with bio-reduction of metal ores, hydrogen production, and/or activated-carbon production
Inventor: MENNELL JAMES
IPC: B01J21/18
Filed: 2021-11-19
Abstract: Improved processes and systems are disclosed for producing renewable hydrogen suitable for reducing metal ores, as well as for producing activated carbon. Some variations provide a process comprising: pyrolyzing biomass to generate a biogenic reagent comprising carbon and a pyrolysis off-gas; converting the pyrolysis off-gas to additional reducing gas and/or heat; reacting at least some of the biogenic reagent with a reactant to generate a reducing gas; and chemically reducing a metal oxide in the presence of the reducing gas. Some variations provide a process for producing renewable hydrogen by biomass pyrolysis to generate a biogenic reagent, conversion of the biogenic reagent to a reducing gas, and separation and recovery of hydrogen from the reducing gas. A reducing-gas composition for reducing a metal oxide is provided, comprising renewable hydrogen according to a hydrogen-isotope analysis. Reacted biogenic reagent may also be recovered as an activated carbon product. Many variations are disclosed.
Patent AU-2021442648-A1 (AU)
Title: Biopsy system and biopsy driver for use therewith
Inventor: ADDISON JORDAN
IPC: A61B10/02
Filed: 2021-04-30
Abstract: A biopsy driver includes a housing, a battery supply, a motor, a trigger, and a control circuit. The control circuit has a trigger switch circuit, a resistance network circuit, and a pulse width modulation circuit. The trigger switch circuit has an OFF state and an ON state. The resistance network circuit is coupled to an input of the pulse width modulation circuit. The pulse width modulation circuit is configured to generate a variable pulse width signal to control a rotational speed of the motor. When the trigger switch circuit is in the ON state, the trigger switch circuit is configured to: connect a negative terminal of the battery supply to the chassis ground, and select a resistance value from the resistance network circuit to select a desired duty cycle of the variable pulse width signal generated by the pulse width modulation circuit.
Patent AU-2021444698-A1 (AU)
Title: Bone screw and sleeve remover
Inventor: MIDDERHOFF STEFAN
IPC: A61B17/70
Filed: 2021-05-10
Abstract: The invention relates to a bone screw (1) having a threaded screw shank (2) and a screw head (3) that in turn has two opposite legs (5) defining a receptacle (4) between them and integrally connected to a tissue-protecting sleeve (8). The tissue-protecting sleeve (8) has a slot (9) that runs from the sleeve's one edge to the opposite edge. The invention further relates to a sleeve remover (12).
Patent AU-2021466980-A1 (AU)
Title: Phase changing gas-lift valves for a wellbore
Inventor: FRIPP MICHAEL LINLEY
IPC: E21B43/12
Filed: 2021-09-30
Abstract: A gas-lift valve in a wellbore may include a valve housing and a flow restrictor. The valve housing may at least in part define a chamber for receiving an actuation fluid. The flow restrictor may have a position that is controllable by adjusting a downhole pressure to change a density of the actuation fluid in the chamber. The gas-lift valve may be positioned on production tubing in an annulus of a wellbore. Controlling the position of the flow restrictor may restrict an opening in the production tubing through which gas may flow.
Patent WO-2023039633-A1 (WO)
Title: A method and system for remediating a wellbore
Inventor: BERTANI ROMOLO LORENZO
IPC: E21B43/34
Filed: 2022-09-15
Abstract: A system and method is disclosed for contaminant extraction from a contaminated region of a borehole. The system includes a production pipe extending from a surface of the earth through a water permeable layer and into an underlying production zone. A side remediation borehole is located proximate the borehole and extends through the water permeable layer towards the production zone, the side remediation borehole including a remediation pipe. A vacuum source is in fluid communication with the side remediation borehole, the vacuum source being configured to extract gaseous contaminants from the side remediation borehole and the region of the borehole.