baber/WOPTO huggingface dataset:
Patent EP-3439697-A1 (EP)
Title: Hydrogel pour réponse immunitaire modifiée à des peptides de chiralité d
Inventor: SEGURA TATIANA
IPC: A61L15/42
Filed: 2017-04-10
Abstract: L'invention concerne un biomatériau de modulation immunitaire comprenant un échafaudage d'hydrogel couplé à un acide D aminé contenant des peptides présentant des propriétés inattendues in vivo. Par exemple, certaines réactions inflammatoires in vivo sont significativement augmentées autour des particules d'échafaudage d'hydrogel contenant des peptides par rapport à des particules qui contiennent à la fois des peptides L et D ou des peptides L seuls. De plus, ces compositions de peptide D s'avèrent en outre améliorer la cicatrisation des plaies et améliorer la résistance à la traction des tissus cicatrisés. Pour ces raisons et d'autres raisons, les matériaux d'hydrogel d'acide D aminé de l'invention sont utiles dans un certain nombre de méthodologies qui visent à moduler la réponse immunitaire et/ou la cicatrisation des plaies.
Patent EP-3519551-A1 (EP)
Inventor: LINDBO LARS SVERKER TURE
IPC: C12C13/00
Filed: 2017-09-29
Abstract: A robotic processing system and method is disclosed for processing materials using a series of containers stored in an automated storage and picking system. Each of the containers performs a specific function on the materials stored therein. The materials are passed form bin to bin via suitable dispensing and transferring means. More specifically the invention disclosed relates to a system for delivering ingredients to a micro-brewery and to methods for brewing small or test batches of beer according to customers' individual requirements.
Patent EP-3466541-A1 (EP)
Inventor: TAKESUE YUKI
IPC: B01J35/04
Filed: 2017-05-12
Abstract: An exhaust gas purification catalyst of the present invention is provided with a base 10 and a catalyst coat layer 30. The catalyst coat layer is provided with Rh and Pd as noble metal catalysts. Herein Rh is disposed in a first-stage upper layer A and a second-stage upper layer C, and Pd is disposed in the first-stage upper layer A and a first-stage lower layer B, and in a second-stage lower layer D. A mass ratio (A Pd /A Rh ) of Pd to Rh, disposed in first-stage upper layer A is 0.5¤(A Pd /A Rh )¤3.
Patent EP-3466080-A1 (EP)
Inventor: ZHOU CHANGYIN
IPC: H04N5/262
Filed: 2017-06-07
Abstract: La présente invention concerne des systèmes et des procédés d'imagerie qui comprennent une pluralité de caméras conçues pour capturer des données d'image vidéo sur la base de champs de vision respectifs d'un environnement. Chaque caméra de la pluralité de caméras est couplée en communication aux caméras voisines de la pluralité de caméras par l'intermédiaire d'une interface de communication. Chaque caméra peut effectuer des opérations, comme la capture de données d'image vidéo du champ de vision respectif et la détermination d'une région de recouvrement. La région de recouvrement comprend une partie de chevauchement des données d'image vidéo capturées par la caméra respective et au moins une des caméras voisines. Les opérations comprennent également le recadrage et la déformation des données d'image vidéo capturées du champ de vision respectif sur la base de la région de recouvrement pour former des données d'image vidéo traitées respectives. Les données d'images vidéo traitées peuvent être téléchargées vers un serveur en nuage et fournies, par l'intermédiaire de liaisons interurbaines multiples, à un dispositif client.
Patent EP-3471789-A1 (EP)
Inventor: WADSWORTH SAM
IPC: A61L27/38
Filed: 2017-06-16
Abstract: Provided herein are meniscus implant compositions, as well as method for making and using the same. The subject meniscus implants find use in repairing and/or replacing damaged or diseased meniscal tissue in a mammalian subject.
Patent EP-3475792-A1 (EP)
Title: Dispositif d'affichage et son procédé de commande
Inventor: LEE YOUNKYUNG
IPC: G06F3/048
Filed: 2017-06-21
Abstract: La présente invention concerne un dispositif d'affichage et un procédé de commande de ce dernier. Selon un mode de réalisation de la présente invention, un dispositif d'affichage comprend une mémoire configurée pour mémoriser au moins un ou plusieurs contenus, au moins un ou plusieurs capteurs, un module d'interface réseau configuré pour communiquer avec au moins une ou plusieurs lumières, un module d'affichage configuré pour produire en sortie le ou les contenus enregistrés dans la mémoire, et un dispositif de commande couplé à la mémoire, au capteur, au module d'interface réseau et au module d'affichage. Dans ce cas, le dispositif de commande commande le module d'affichage pour produire en sortie un contenu spécifique enregistré dans la mémoire à une synchronisation spécifique, et commande le module d'interface réseau pour émettre un signal de commande à destination d'une lumière spécifique à la synchronisation spécifique.
Patent EP-3547916-A1 (EP)
Inventor: ANNONI ELIZABETH M
IPC: A61N1/36
Filed: 2017-11-29
Abstract: This document discusses, among other things, systems and methods for detecting stroke. A system may comprise a sensor circuit for sensing a physiological signal, and a second sensor to detect a physical state change. The physical state change may include a transition in physical activity, posture, or sleep state. A stroke risk circuit may detect, from the sensed physiological signal, a signal indicative of blood pressure surge (BPS) in response to one or more physical state changes. The system may generate a stroke risk indicator indicating a risk of developing an impending stroke event using the detected BPS. The system includes an output unit that outputs the stroke risk indicator to a user or a process.
Patent EP-3555000-A1 (EP)
Inventor: GALLIS KARL W
IPC: C01B33/193
Filed: 2017-12-01
Abstract: Silica particles having a BET surface area from 0.1 to 7m 2 /g, a pack density from 35 to 55 lb/ft 3 , an Einlehner abrasion value from 8 to 25 mg lost/100,000 revolutions, a total mercury intrusion pore volume from 0.7 to 1.2cc/g,and a stannous compatibility from 70 to 99%, are disclosed, as well as methods for making these silica particles.
Patent EP-3480035-A1 (EP)
Inventor: KIMURA KAZUSHI
IPC: B60C17/06
Filed: 2017-06-28
Abstract: A tire-wheel assembly with durability during run-flat traveling improved beyond conventional levels is provided. The tire-wheel assembly includes a run-flat support member disposed on a rim (1) within a cavity portion of a pneumatic tire (2) and including a support surface formed on an outer circumference; the run-flat support member being a bladder (4) comprising a foamed body (3) therein and being disposed in an annular manner around an outer circumference of the rim.
Patent EP-3556130-A1 (EP)
Inventor: BOUVET BERTRAND
IPC: H04W88/08
Filed: 2017-12-13
Abstract: The invention relates to a monitoring method implemented by an access point for a network that can maintain an address association table, and comprises: a step (F20) of selecting at least two entries in the address association table; a step (F30) of storing at least one predetermined characteristic obtained over a predefined period of time for each inflow and each outflow associated with the selected entries; a step (F40) of comparing, for at least one pair of selected entries, at least one stored characteristic for an inflow associated with one of the entries of the pair with said at least one corresponding stored characteristic for an outflow associated with the other entry of the pair; and if, for at least one pair of entries, the comparison step indicates that an inflow associated with one of the entries of the pair transports an application content of the same nature as an outflow associated with the other entry of the pair, a step (F70) of detecting a risk of fraud.
Patent EP-3548886-A1 (EP)
Inventor: Balashanmugam Soban
IPC: G01N33/28
Filed: 2017-11-28
Abstract: A method for predicting the critical solvent power of a visbroken residue stream of interest, CSP VisRes(OI)  comprises predicting CSP VisRes(OI)  from the critical percentage titrant of an atmospheric residue stream, CPT AR , the atmospheric residue stream being derived from the same crude oil as the visbroken residue stream of interest. A method for predicting the solvent power of a visbroken residue stream of interest, SP VisRes(OI) , comprises predicting SP VisRes(OI)  from the critical solvent power of the visbroken residue stream, CSP VisRes , and the critical percentage titrant of the visbroken residue stream, CPT VisRes . CPT VisRes  is derived from the critical percentage cetane of the visbroken residue stream, CPC VisRes , which, in turn, is calculated from the P-value of the visbroken residue stream. The methods may be used to predict the stability of a fuel oil containing the visbroken residue.
Patent EP-3463063-A1 (EP)
Inventor: COHEN YANIV
IPC: A61B5/00
Filed: 2017-07-05
Abstract: La présente invention concerne un dispositif de diagnostic de tissu biologique en temps réel comprenant : un moyen de préparation d'un échantillon de tissu avant une procédure de mesure; un moyen de positionnement d'un élément ATR et des miroirs de façon à effectuer un étalonnage du système; un moyen d'irradiation d'un échantillon avec un rayonnement IR à l'aide de l'élément ATR et d'un ensemble opto-mécanique; un moyen d'enregistrement du spectre d'absorption d'un échantillon en cours de test; un moyen de réalisation d'une transformation de Fourier du spectre d'absorption obtenu en un spectre FT-IR; un moyen de calcul des caractéristiques du tissu sur la base d'un traitement de signal; un moyen de comparaison des caractéristiques dans une plage de nombres d'ondes présélectionnée avec les spectres de référence préparés et stockés dans une base de données. L'invention concerne également un procédé de diagnostic de tissu biologique en temps réel comprenant uniquement les étapes suivantes : régler les paramètres de fonctionnement; balayer l'air de l'environnement ambiant en vue d'obtenir un spectre de fond; placer un tissu en cours de test en contact étroit avec un ATR; sécher le tissu de façon à au moins réduire la teneur en humidité de l'échantillon de tissu; régler automatiquement au moins un miroir du système, réalisant ainsi un étalonnage du système; et obtenir un spectre de l'échantillon de tissu.
Patent EP-3436021-A1 (EP)
Inventor: LIPPA ARNOLD STAN
IPC: A61K31/535
Filed: 2017-03-25
Abstract: The present invention relates to ampakines, including low impact ampakines, and pharmaceutical compositions and methods employing ampakines for treating central nervous system (CNS) disorders, including attention deficit disorders. Novel compositions and methods are provided employing anti-ADHD ampakines to treat attention deficit hyperactivity disorder (ADHD) and related cognitive, behavioral and psychiatric conditions.
Patent EP-3562999-A1 (EP)
Title: Vorrichtung zum bewegen einer zungenschiene einer weiche
Inventor: STARIBACHER PETER
IPC: E01B7/02
Filed: 2017-12-21
Abstract: Vorrichtung zum Bewegen einer Zungenschiene (2) einer Weiche, mit einem an einer Backenschiene (3) angebrachten Haltelement (7) und mindestens einer darauf befestigten Rolle (1), deren Drehachse im Wesentlichen parallel zum Schienenverlauf ist, und die so angeordnet ist, dass die Zungenschiene (2) von einer unteren Anliegeposition an der Backenschiene (3) auf die Rolle (1) zu einer abliegenden Position aufrollen kann, und mit einem Federelement (13). Ein vereinfachter Aufbau der Vorrichtung kann dadurch erreicht werden, dass das Federelement (13) im Inneren der Rolle (1) angeordnet ist und dass die Rolle (1) durch mindestens eine Schraubverbindung befestigt ist und in einer Gleitschiene (7a) am Halteelement (7) verstellbar festgelegt ist.
Patent EP-3484404-A1 (EP)
Inventor: TEODORESCU DEBBIE LIN
IPC: A61B46/27
Filed: 2017-07-14
Abstract: A portable surgical system including a transparent and flexible plastic enclosure (1) is disclosed. The enclosure is attached reversibly to the patient's body encompassing the surgical site such as to isolate and regulate the immediate environment of the surgical site, and to reduce bodily fluid splatters from the surgical site to the surgical providers. The enclosure is inflated with filtered air. Arm ports (8) are integrated into the enclosure to allow access to the inside of the enclosure by either provider arms or augmenting instrumentation taking the place of arms such as laparoscopes or robots. Material ports (10) maintain enclosure environmental integrity but allow the passing of anatomical specimens, instruments, and other materials into and out of the enclosure (1) during a procedure. The portable surgical system is lightweight and can be used in conventional operating rooms to improve sterility, or in other circumstances where no operating room is available, such as field hospitals.
Patent EP-3489283-A1 (EP)
Inventor: KAWAMURA SATOSHI
IPC: C08L67/02
Filed: 2017-07-14
Abstract: This invention provides an easy-to-tear resin film. Such easy-to-tear resin film is an easy-to-tear, unstretched resin film composed of a blend of a polyethylene terephthalate-based resin with the second resin having a difference in SP value from the polyethylene terephthalate-based resin of 1.1 to 4.0 (cal/cm 3 ) 0.5 . This invention also provides a laminate film 1B for a packaging material comprising the easy-to-tear, unstretched resin film 10 between the inner layer film 20 serving as a heat seal surface and the surface layer film 30 comprising an isophthalic acid-modified polyethylene terephthalate resin having a copolymerization ratio of isophthalic acid component of 0 mol% to 5 mol%.
Patent EP-3554346-A1 (EP)
Inventor: JONES MITCHELL LAWRENCE
IPC: A61M31/00
Filed: 2017-12-14
Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an immunosuppressant.
Patent EP-3496641-A1 (EP)
Title: Dispositifs et méthodes d'administration de fluide à un tissu pendant une thérapie ablative
Inventor: CURLEY MICHAEL G
IPC: A61B18/14
Filed: 2017-07-31
Abstract: L'invention concerne des dispositifs et des méthodes d'administration de fluide à un tissu pendant une thérapie ablative. Un dispositif donné à titre d'exemple peut comprendre un corps allongé comportant une lumière interne, des orifices de sortie, et un élément d'ablation conçu pour chauffer un tissu. Une résistance à l'écoulement du corps allongé peut s'accroître sur une longueur du corps allongé comportant les orifices de sortie dans un sens proximal à distal. Ceci peut être obtenu, par exemple, par variation de la taille ou de l'espacement relatif des orifices de sortie, réduction d'une section transversale de la lumière interne par laquelle un fluide peut s'écouler à l'aide d'un déflecteur d'écoulement ou de parois latérales de lumière interne coniques, ou limitation du rapport entre une surface totale des orifices de sortie et une section transversale de la lumière interne. L'ajustement de la résistance à l'écoulement du corps allongé peut permettre une distribution de fluide plus uniforme ou la distribution non uniforme recherchée.
Patent EP-3500671-A1 (EP)
Inventor: ZHANG FENG
IPC: C12N15/11
Filed: 2017-08-17
Abstract: Les modes de réalisation divulgués ici se rapportent à des protéines effectrices CRISPR-Cas ingéniérisées qui comprennent au moins une modification par rapport à une protéine effectrice CRISPR-Cas non ingéniérisée, qui améliore la liaison du complexe CRISPR au site de liaison et/ou modifie une préférence d'édition par rapport au type sauvage. Dans certains modes de réalisation donnés à titre d'exemple, la protéine effectrice CRISPR-Cas est une protéine effectrice de Type V. Dans certains autres modes de réalisation donnés à titre d'exemple, la protéine effectrice de Type V est Cpfl. Des modes de réalisation divulgués ici concernent des vecteurs viraux pour l'administration de protéines effectrices CRISPR-Cas, dont Cpfl. Dans certains modes de réalisation donnés à titre d'exemple, les vecteurs sont conçus de manière à permettre l'encapsidation de la protéine effectrice CRISPR-Cas à l'intérieur d'un seul vecteur. Il existe également un intérêt accru pour la conception de promoteurs compacts pour l'emballage et ainsi l'expression de transgènes plus grands pour une administration ciblée et une spécificité tissulaire. Ainsi, dans un autre aspect, certains modes de réalisation de la présente invention concernent des construction, des vecteurs d'administration et des méthodes d'administration de gènes plus grands pour une administration systémique.
Patent EP-3503920-A1 (EP)
Inventor: LI BAIYONG
IPC: A61K39/395
Filed: 2017-08-21
Abstract: The present invention belongs to the fields of tumor therapy and molecular immunology. The present invention relates to an anti-CTLA4 antibody, pharmaceutical composition and use thereof. The anti-CTLA4 antibody of the present invention can specifically bind CTLA4, and can very effectively block the binding of CLTA4 to B7.
Patent EP-3515438-A1 (EP)
Inventor: BARRETT STEPHANIE E
IPC: A61K31/4375
Filed: 2017-09-15
Abstract: This invention relates to novel implant drug delivery systems for long-acting delivery of integrase inhibitors. These compositions are useful for the treatment or prevention of human immunodeficiency virus (HIV) infection.
Patent EP-3521417-A1 (EP)
Inventor: ITO KOJU
IPC: C12N5/0775
Filed: 2017-09-15
Abstract: Provided are a method for producing a cell tissue, including a culturing step of culturing cells capable of serving as a feeder inside opening pores and communicating pores of a porous film having a plurality of the opening pores provided on a surface thereof and the communicating pores communicating mutually adjacent opening pores with one another; and a porous film including a plurality of opening pores provided on a surface thereof and communicating pores communicating mutually adjacent opening pores with one another.
Patent EP-3529476-A1 (EP)
Inventor: GAYNOR JOHN
IPC: F02D13/02
Filed: 2017-10-11
Abstract: The present invention relates to a method for controlling a compression-ignition internal combustion engine (101), said internal combustion engine (101 having at least one combustion chamber (i1-i6), wherein intake of air to said combustion chamber is controlled using an intake valve, and wherein evacuation of said combustion chamber is controlled using an exhaust valve. The method comprises: - controlling opening of said intake valve and closing of said exhaust valve in dependence of the position of a reciprocating member in said combustion chamber, wherein opening of said intake valve and closing of said exhaust valve, respectively, in relation to the position of said reciprocating member is individually controllable, and - controlling opening and closing in relation to the position of said reciprocating member on the basis of a first control parameter, wherein said opening and closing of said intake valve and exhaust valve, respectively, are controlled such that an actual value of said control parameter is adjusted towards a desired value of said control parameter.
Patent EP-3532623-A1 (EP)
Inventor: BANERJEE ARUNAVA STEVEN
IPC: B25J7/00
Filed: 2017-10-31
Abstract: A method of controlling a needle actuator to interact with a cell is provided, the method comprising: providing an actuator comprising a tower, a stage and a needle, wherein the needle is mounted on the stage; applying an electrostatic potential between the tower and the stage to retract the needle; moving the actuator towards the cell; reducing the potential so as to allow the stage and needle to move towards the cell; applying calibration data to detect when the needle has pierced the cell; and reducing the potential further once it has been detected that the needle has pierced the cell. The cell can be a biological cell. The needle can be a micro-needle and the stage can be a micro-stage.
Patent EP-3516862-A1 (EP)
Title: Systems and methods for exposure control
Inventor: QU ERPING
IPC: H04N5/235
Filed: 2017-10-24
Abstract: The present disclosure relates to systems and methods for determining the exposure setting of an imaging device having a set of exposure parameters. A target luma of the imaging device may be determined. A correspondence table may be obtained. The correspondence table may relate to a plurality of reference luma values and a plurality of groups of operation values of the set of exposure parameters, a group of operation values corresponding to a reference luma value. A reference luma value and a group of operation values of the set of exposure parameters may be identified based on the target luma and the correspondence table. An adjustment of at least one exposure parameter of the imaging device may be determined based on the identified group of operation values. The at least one exposure parameter of the imaging device may be adjusted based on the determined adjustment.
Patent EP-3519426-A1 (EP)
Inventor: RAJAMANI LAKSHMINARAYANAN
IPC: C07K14/00
Filed: 2017-10-31
Abstract: The present disclosure relates to a peptide comprising at least five amino acid residues, wherein at least one amino acid residue is modified to an epsilon-lysine, delta-ornithine, gamma-2, 4-diaminobutyric acid, beta-2,3-diaminopropionic acid, with the peptide also comprising at least one non-epsilon lysine, non-delta-ornithine, non-gamma-2, 4-diaminobutyric acid or non-beta-2,3-diaminopropionic acid, and wherein the peptide displays a reduced or no cytotoxicity when compared to an equivalent non-modified peptide. In a preferred embodiment, the modifications are to the melittin or mastoparan B peptides, and comprise the substitution of at least one a-lysine residue for an ε-lysine residue, and the modified peptides display antimicrobial activity. The present disclosure is also directed to pharmaceutical compositions, kits, ophthalmic preparations comprising the modified antimicrobial peptides and use of the modified antimicrobial peptides in methods of inhibiting growth of microorganisms, methods of managing microbial colonization, methods of treating proliferative disease, and methods of treating inflammation. The present disclosure also relates to a method of improving the therapeutic index (safety) of an isolated peptide comprising the aforementioned modification.
Patent EP-3538194-A1 (EP)
Inventor: CHIN ALBERT K
IPC: A61M25/10
Filed: 2017-11-03
Abstract: Systems for providing access across a site of obstruction and methods for manufacturing and using such systems are provided. Such systems may include a cannula having a lumen, an everting member coupled to the cannula, and a push assembly having a pathway. The push assembly may be slidably disposed within the lumen of the cannula and connected to a proximal end of the everting member to move the everting member from an inverted position inside the cannula to an everted position outside the cannula. The systems may also include a tube having a passageway, the tube slidably disposed within the pathway of the push assembly and extending through a proximal end of the push assembly into the pathway of the push assembly to selectively move from a first position inside the push assembly to a second position outside the push assembly.
Patent EP-3539581-A1 (EP)
Inventor: CHANG YUNG
IPC: C08F220/56
Filed: 2017-11-09
Abstract: Disclosed is a polymer for capturing or separating leukocytes. The polymer is prepared by a polymerization reaction of monomers containing an amino and hydroxyl. The monomer containing an amino and hydroxyl has the structure of formula (1):In formula (1), R1 is independently selected from the group consisting of a hydrogen, a methyl, an ethyl, a hydroxyl, any one of C1 to C12 long carbon chains, and a benzene ring, R2 is independently selected from the group consisting of a hydrogen, a methyl, an ethyl, any one of from C1 to C6 long carbon chains, an amino, and a benzene ring, and n is an integer of 1 to 5.