baber/WOPTO huggingface dataset:
Patent NZ-206505-A (NZ)
Title: Preparation of chiral azetidinones and intermediates
Inventor: WEI C-C
IPC: C07D417/12
Filed: 1983-12-07
Abstract: Manufacture of chiral azetidinones of the general formula 
<CHEM>
 wherein R is an amino protecting group and M +/ &cir& is a cation, starting from L-ascorbic acid. Several alternatives lead, over a number of novel intermediates, to a novel intermediate of the formula 
<CHEM>
 wherein R and M +/ &cir& are as above and R<9>O- is a leaving group, which is treated with an alkali metal carbonate or bicarbonate, whereupon the compound of formula II is recovered from the reaction mixture. 
<??>The compounds of formula II are useful for preparing the new sulfazecin related antibiotic compound of the formula 
<CHEM>
 
<??>This new antibiotic is similar in activity to the antibiotic azthreonam and useful in treating infectious diseases caused by gram negative microorganisms, particularly P. aeruginosa.
Patent NZ-222004-A (NZ)
Title: Making soft paper: dry fibres deposited on wet-formed layer while it is still wet
Inventor: WEDIN IRENE KATARINA
IPC: D21F11/00
Filed: 1987-09-30
Abstract: PCT No. PCT/SE87/00424 Sec. 371 Date Mar. 14, 1989 Sec. 102(e) Date Mar. 14, 1989 PCT Filed Sep. 22, 1987 PCT Pub. No. WO88/02416 PCT Pub. Date Apr. 7, 1988.Soft paper from cellulose fibres is manufactured by wet-forming a first fibre layer. Thereafter air-borne dry fibres are deposited directly on one or both sides of the wet-formed layer while this is still wet, so that a second and possibly a third fibre layer are formed on the first one. Fibre bindings thereby arise between the layers. The wet-formed fibre layer gives the soft paper its strength, while the dry-formed fibers give a soft surface.
Patent NZ-227731-A (NZ)
Title: Method of detection of hepatitis b virus antigens
Inventor: MILICH DAVID R
IPC: G01N33/48
Filed: 1985-03-07
Abstract: Chemically synthesized polypeptides include amino acid residue sequences that substantially correspond to the amino acid residue sequences of T cell and B cell determinant portions of a natural, pathogen-related protein, in particular, a hepatitis B virus surface antigen (HBsAg). When administered to a host alone, as polymers or as carrier-bound conjugates, the polypeptides induce the proliferation of thymus-derived cells in hosts primed against hepatitis B virus.
Patent NZ-240165-A (NZ)
Title: Process for the preparation of crystal-water-free crystalline lactulose
Inventor: PLUIM HENK
IPC: C07H3/04
Filed: 1991-10-09
Abstract: The present invention is concerned with a method for the preparation of crystal-water-free crystalline lactulose by subjecting an aqeous solution or suspension of lactulose to simultaneous reduction of the water content by evaporation and continuous stirring, optionally in the presence of seed crystals, until a free-flowing solid powder is obtained.
Patent NZ-242462-A (NZ)
Title: Recovering a polymer latex from whitewater emulsion using an ultrafiltration membrane; apparatus
Inventor: BUCKLEY RANDALL GEORGE
IPC: C08J11/00
Filed: 1992-04-23
Abstract: Polymer is recovered by ultrafiltration from a whitewater waste stream generated during the production of a polymer latex. The whitewater stream is circulated through an ultrafiltration system in laminar flow, under conditions of shear insufficient to destabilize the whitewater emulsion, and the recovered polymer is in the form of an emulsion which may be blended at significant levels into the original polymer latex without degrading its performance properties. <IMAGE>
Patent NZ-254309-A (NZ)
Title: Alpha-[tert.-aminomethyl)-benzenemethanol derivatives for treating urinary incontinence
Inventor: WILLMAN NILS-ERIK
IPC: C07C317/26
Filed: 1993-07-20
Abstract: PCT No. PCT/SE93/00635 Sec. 371 Date Jan. 18, 1995 Sec. 102(e) Date Jan. 18, 1995 PCT Filed Jul. 20, 1993 PCT Pub. No. WO94/02442 PCT Pub. Date Feb. 3, 1994.    <IMAGE>  (I)  Compounds of formula (I) and their physiologically acceptable salts thereof, their use as therapeutical substances, pharmaceutical compositions containing them, and methods for preparing the compounds.
Patent NZ-279199-A (NZ)
Title: Pyrazino[2',1':6,1]pyrido[3,4-6]indole-1,4-dione derivatives and medicaments
Inventor: DAUGAN ALAIN CLAUDE-MARIE
IPC: A61P29/00
Filed: 1995-01-19
Abstract: A compound of formula (I) and salts and solvates thereof, in which: R0 represents hydrogen, halogen or C1-6 alkyl; R1 represents hydrogen, C1-6alkyl, C2-6 alkenyl, C2-6 alkynyl, haloC1-6alkyl, C3-8cyloalkyl, C3-8cycloalkylC1-3alkyl, arylC1-3alkyl or heteroarylC1-3alkyl; R2 represents an optionally substituted monocyclic aromatic ring selected from benzene, thiophene, furan and pyridine or an optionally substituted bicyclic ring attached to the rest of the molecule via one of the benzene ring carbon atoms and wherein the fused ring A is a 5- or 6-membered ring which may be saturated or partially or fully unsaturated and comprises carbon atoms and optionally one or two heteroatoms selected from oxygen, sulphur and nitrogen; and R3 represents hydrogen or C1-3 alkyl, or R1 and R3 together represent a 3- or 4-membered alkyl or alkenyl chain. A compound of formula (I) is a potent and selective inhibitor of cyclic guanosine 3'5'-monophosphate specific phosphodiesterase (cGMP specific PDE) having a utility in a variety of therapeutic areas where such inhibition is beneficial, including the treatment of cardiovascular disorders.
Patent NZ-299314-A (NZ)
Title: Cyclic peptide for inhibiting parasitic and antifungal activity
Inventor: BURKHARDT FREDERICK JOSEPH
IPC: A61P31/10
Filed: 1993-03-15
Abstract: Use of cyclic peptides of formula (I) for treating parasitic and antifungal infections.  In particular, the use of the echinocandin class of cyclic peptide antifungal agents against the protozoan, Pneumocystis carinii is disclosed.
Patent NZ-305168-A (NZ)
Title: Preparation of sodium chloride aerosol formulations
Inventor: CLARK ANDREW R
IPC: A61K9/12
Filed: 1996-03-13
Abstract: Disclosed herein is a method for the preparation of sodium chloride formulations having a substantially uniform particle size suitable to ensure the dispersible properties for inhalation into the lungs of a subject. The formulations thus prepared are also the subject of this disclosure. The method involves jet milling coarse sodium chloride in one or preferably two or more procedures using air pressure suitable to produce particles having a significant fraction that are less than about 7 microns in size. Immediately following the milling, the particles are vacuum dried in an oven using a temperature and time suitable to cure the product to prevent substantial aggregation over time.
Patent NZ-333864-A (NZ)
Title: Polymer-lipid microencapsulated gases for use as imaging agents
Inventor: BERNSTEIN HOWARD
IPC: A61K49/22
Filed: 1997-02-27
Abstract: It has been discovered that the incorporation of gases, especially fluorinated gases such as perfluorocarbons, into microparticles formed from the combination of a natural or synthetic polymer and lipid have significantly enhanced echogenicity as compared with microparticles not including the lipid. Compounds other than lipids which are hydrophobic and limit the penetration and/or uptake of water into the microparticles can also be incorporated into the microparticles to enhance echogenicity. In the preferred embodiment, the polymers are synthetic biodegradable polymers. The microparticles are manufactured with a diameter suitable for the targeted tissue to be imaged, for example, with a diameter of between 0.5 and 8 microns for intravascular administration, and a diameter of between 0.5 and 5 mm for oral administration for imaging of the gastrointestinal tract or other lumens. Preferred polymers are polyhydroxy acids such as polylactic acid-co-glycolic acid, most preferably conjugated to polyethylene glycol or other materials inhibiting uptake by the reticuloendothelial system (RES). The most preferred lipids are phospholipids, preferably dipalmitoylphosphatidylcholine (DPPC), distearoylphosphatidylcholine (DSPC), diarachidoylphosphatidylcholine (DAPC), dibehenoylphosphatidylcholine (DBPC), ditricosanoylphosphatidylcholine, dilignoceroylphatidylcholine (DLPC), incorporated at a ratio of between 0.01-30 (w lipid/w polymer), most preferably between 0.1-10 (w lipid/w polymer). Microparticles for imaging using other detectable agents can be similarly manufactured.
Patent NZ-336282-A (NZ)
Title: Detergent comprising a surfactant, an alkali and an indicator to show when the surface is cleaned and cleaning method therefor
Inventor: USHIJIMA TAKASHI
IPC: C11D3/30
Filed: 1998-10-08
Abstract: This detergent is for use in a cleaning method comprising adhering bubbles of a detergent liquid to the surface of an object to be cleaned, (e.g., a tire wheel), and removing the adherent dirt from the object surface with the detergent bubbles. The detergent is characterized by comprising a)	a surfactant, b)	at least one alkali compound selected from the group consisting of ammonia and aminated alkali compounds, and c)	at least one indicator which changes its color upon a change from alkalinity to neutrality, the alkali compound being contained in such an amount that the alkali compound disappears through reaction with carbon dioxide in the same period as that required for removing almost all the dirt from the surface of the object.
Patent NZ-500763-A (NZ)
Title: Use of PEG 12000-IFN alpha in treating viral infection
Inventor: CUTLER DAVID L
IPC: A61K47/48
Filed: 1998-04-28
Abstract: A method is disclosed comprising administration of a PEG12000-IFN alpha conjugate at 0.5-2.0 micrograms/kilogram body weight to an individual with a viral infection, such as hepatitis C, who is susceptible to treatment with interferon alpha.
Patent NZ-508008-A (NZ)
Title: Method for preventing replication in cryptosporidium parvum using ultraviolet light
Inventor: STEVENS R D SAMUEL
IPC: C02F1/32
Filed: 1999-05-05
Abstract: A method for prevention of infection from cryptosporidium oocysts in water by irradiating the water with ultraviolet light in a range of 200 to 300 nm in doses of about 10 mJ/cm2 to 175 mJ/cm2
Patent NZ-511503-A (NZ)
Title: Manufacture of clevidipine by reacting an inorganic salt of a carboxylic acid with choromethyl butyrate
Inventor: MATTSON ANDERS
IPC: C07D211/90
Filed: 1999-11-22
Abstract: A method for the manufacture of clevidipine comprises mixing a compound of the formula I wherein A+ is an inorganic cation, so that that the compound is in salt form, with a solvent and then reacting the compound of formula I with chloromethyl butyrate to form clevidipine. Also described is a method for the manufacture of clevidipine in the form of a pharmaceutical preparation.
Patent NZ-512142-A (NZ)
Title: Strapping machine with restriction device to prevent jamming
Inventor: BOBREN ALLAN J
IPC: B65B13/18
Filed: 2001-06-05
Abstract: A restriction device for strapping machine to prevent strapping material (15), remaining after a break in the material (15) from being drawn, by gravity or inertia, into the strapping machine slack box.  The restriction device comprises a winder (12), a strap gate (14), a slack box and upper (18) and lower (20) guides.  The upper (18) and lower (20) guides are rotationally connected at a first end (22) and urged apart at a second end, forming a guide between the winder (12) and the strap gate (14), the upper guide (18) being disposed towards the winder (12) and the lower guide (20) being disposed towards the strap gate (20). A variable gap (17) is created by the relative movement of the upper (18) and lower (20) guides by either strap tension or weight, thus assisting in orderly movement of strapping material (15) through the machine.
Patent NZ-513589-A (NZ)
Title: Packaging apparatus wherein one or more packaging devices are on sliding 'drawers' and can be moved to facilitate servicing.
Inventor: MELVILLE RICHARD ARCHER
IPC: B65B59/04
Filed: 2001-08-15
Abstract: Disclosed herein is a packaging apparatus (10) for producing packages of variable lengths from rolls of plastic film wherein the apparatus produces packages to be accessed at a first, or front, end (22) of the apparatus (10) and the apparatus may be serviced from a second, or rear, end (24) of the apparatus. The apparatus (10) comprises a frame (12) wherein a plurality of packaging devices, two being shown, (14, 16) are slidably mounted on a sliding roller mounting mechanism (18, 20). Each packaging device (14, 16) can be pulled backwards from the frame (12) along a sliding roller mounting mechanism (18, 20) such that each packaging device (14, 16) may be serviced at the rear of the frame (12) without interfering with the operation of the other packaging devices.
Patent NZ-514780-A (NZ)
Title: Automatic veterinary medicament delivery system
Inventor: EIDSON WILBUR L
IPC: A61D7/00
Filed: 2001-10-11
Abstract: A electrically powered, plunger-free, valve-free adjustable veterinary delivery system for the administration of veterinary pharmaceuticals or vaccines to a variety of poultry or livestock. The delivery system includes a rechargeable battery positioned to power an electric motor, which is used to actuate a peristaltic pump that propels pre-determined quantity of fluid medicament through the system for delivery. The system teaches adjustable dosage control of the fluid medicament by means of an electronic control unit, which uses a photo-optic sensor to calibrate dosage. The veterinary delivery system includes several hand-held injection devices from which to choose, depending on desired use, each having a push-button trigger, at least one needle, a headlight, signal lights, optional dye marking means, and an optional mixing chamber for mixing medicaments at the time of delivery of the medicament, the hand-held injection devices being easily connected and disconnected by means of quick connect fluid couplers for being in fluid communication with the system and a nine-pin amp electrical connector for being in electronic communication with the control unit.
Patent NZ-518480-A (NZ)
Title: Methods and compositions utilizing quinazolinones
Inventor: FINER JEFFREY T
IPC: G01N33/50
Filed: 2000-10-26
Abstract: A compound of formulae (I)-(IV) as described for treating cellular proliferative diseases comprising where: R1 is chosen from hydrogen, alkyl, aryl, alkylaryl, heteroaryl, alkylheteroaryl, substituted alkyl, substituted aryl, substituted alkylaryl, substituted heteroaryl, and substituted alkylheteroaryl; R2 and R2' are independently chosen from hydrogen, alkyl, oxaalkyl, aryl, alkylaryl, heteroaryl, alkylheteroaryl, substituted alkyl, substituted aryl, substituted alkylaryl, substituted heteroaryl, and substituted alkylheteroaryl; or R2 and R2' taken together form a 3-to 7-membered ring; R3 is chosen from hydrogen, alkyl, aryl, alkylaryl, heteroaryl, alkylheteroaryl, substituted alkyl, substituted aryl, substituted alkylaryl, substituted heteroaryl, substituted alkylheteroaryl, oxaalkyl, oxaalkylaryl, substituted oxaalkylaryl, R15O-and R15-NH; R3' is chosen from hydrogen, alkyl, aryl, alkylaryl, heteroaryl, alkylheteroaryl, substituted alkyl, substituted aryl, substituted alkylaryl, substituted heteroaryl, substituted alkylheteroaryl, and Rl5-NH-; R3" is chosen from alkyl, aryl, alkylaryl, heteroaryl, alkylheteroaryl, substituted alkyl, substituted aryl, substituted alkylaryl, substituted heteroaryl, and substituted alkylheteroaryl; R4 is -(CH)mOH or -(CH2)pR16; R5, R6, R7 and R8 are independently chosen from hydrogen, alkoxy, halogen, fluoroalkyl, nitro, dialkylamino, alkylsulfonyl, alkylsulfonamido, sulfonamidoalkyl, sulfonamidoaryl, alkylthio, carboxyalkyl, carboxamido, aminocarbonyl, aryl, and heteroaryl; R15 is chosen from alkyl, aryl, alkylaryl, heteroaryl, alkylheteroaryl, substituted alkyl, substituted aryl, substituted alkylaryl, substituted heteroaryl, and substituted alkylheteroaryl; m is 2 or 3; p is 1 to 3; and R16 is chosen from amino, propylamino, azetidinyl. Cellular proliferative diseases may include a disorder associated with KSP activity, cancer, hyperplasia, cardiac hypertrophy, immune disorders and inflammation.
Patent NZ-519979-A (NZ)
Title: Accelerating the cheese ripening process using a biological agent that is a micoorganisms treated with a surface active agent
Inventor: SMITH MARK RODNEY
IPC: A23C19/032
Filed: 2000-12-22
Abstract: A method for accelerated cheese ripening uses a microorganism that has been treated with a surfactant or a detergent that is not an attenuated lactic acid bacteria. Preferably the microorganism is a finisher organism and does not play a role in acidification in cheese.
Patent NZ-522210-A (NZ)
Title: A method for sequestering a fluid within a hydrocarbon containing formation
Inventor: VINEGAR HAROLD J
IPC: E21B43/24
Filed: 2001-04-24
Abstract: A method for sequestering a fluid is disclosed, which method comprises sequestering the fluid within a portion of an in-situ heat treated hydrocarbon containing formation, such as a coal seam in which hydrocarbons have been pyrolysed, of which at least a portion has preferably a permeability of at least 100 millidarcy.
Patent NZ-530298-A (NZ)
Title: A filter cartridge
Inventor: MARHEINE PHILIP CHARLES
IPC: B01D29/07
Filed: 2002-07-03
Abstract: A filter cartridge (10), in this case comprising an injection moulded cylindrical plastics body (11) having spaced anti-tracking ribs (12) which are disposed unevenly along the inner surface (13) of the hollow body (11). First and second paper rolls as filter elements (14 and 15) have been pushed under compression into the hollow body (11) and are separated by spacer means (16) located centrally within the hollow body (11). Spacer means (16) is made from two separate spacers (18) which are generally made in the form of a spoked wheel type arrangement. Each spacer (18) comprises an outer ring (19) and an inner ring (20), the inner ring (20) has four apertures or recesses (21) on its top and offset by 45 degrees equally on its opposite side are four more equally spaced apertures (21) making a total of eight, the apertures provide flow through passages (21) through the inner ring (20), plastic connector portions (22) extend radially between the rings (19 and 20).
Patent NZ-530605-A (NZ)
Title: A batten
Inventor: NICHOLLS KEITH GORDON
IPC: E04D12/00
Filed: 2004-01-14
Abstract: A batten (10) to be secured to a frame (11) by a threaded fastener (12). The batten is of a channeled configuration and includes a pair of longitudinally extending mounted flanges (17, 18) that are to be attached to the frame. Spaced from the flanges is a further flange (21) having flange portions (22, 23, 24) adapted to be sealingly attached to sheets (13, 14).
Patent NZ-534159-A (NZ)
Title: Vaccines comprising flaviviruses with one or more hinge region mutations that reduce viscerotropism of the flaviviruses
Inventor: MONATH THOMAS P
IPC: C12N7/00
Filed: 2003-01-15
Abstract: Described are flaviviruses including one or more hinge region mutations that reduce viscerotropism of the flaviviruses. These flaviviruses can be, for example, yellow fever virus (e.g., a yellow fever virus vaccine strain); a viscerotropic flavivirus selected from the group consisting of Dengue virus, West Nile virus, Wesselsbron virus, Kyasanur Forest Disease virus, and Omsk Hemorrhagic fever virus; or a chimeric flavivirus. In one example of a chimeric flavivirus, the chimera includes the capsid and non-structural proteins of a first flavivirus virus (e.g., a yellow fever virus) and the pre-membrane and envelope proteins of a second flavivirus (e.g., a Japanese encephalitis virus or a Dengue virus (e.g., Dengue virus 1, 2, 3, or 4) ) including an envelope protein mutation that decreases viscerotropism of the chimeric flavivirus.
Patent NZ-536064-A (NZ)
Title: Immunological methods and compositions for the treatment of alzheimer's disease
Inventor: ST GEORGE-HYSLOP PETER
IPC: C07K14/47
Filed: 2003-04-07
Abstract: Disclosed are immunogenic compositions and peptides that comprise residues 4-10 (FRHDSGY) of the amyloid peptide Abeta42. The invention further relates to antibodies that bind to the Abeta(4-10) antigenic determinant. The invention also relates to methods for designing small molecule inhibitors of amyloid deposition.
Patent NZ-537445-A (NZ)
Title: Method and apparatus for extracting toner from toner cartridges
Inventor: MORRISS STEPHEN
IPC: B29B17/02
Filed: 2003-06-13
Abstract: The invention provides a method and apparatus for recycling toner cartridges. A shredder (1) breaks up the toner cartridges into pieces, thereby releasing any toner from within the otherwise substantially sealed cartridges. The toner pieces along with any free toner powder are then fed through a separation stage including a mechanical separator (3) and a trommel separator (4). Each separator employs a sifting screen, which allow smaller particles to fall though the screen while holding back the larger pieces. Both separators agitate the pieces to mobilise the smaller particles. A vacuum extraction system (7) is used to withdraw air from around the cartridge pieces and an air ioniser is included for feeding ionised air into the apparatus to reduce any static electronic charge build up. The toner is the removed from the extracted air by a dust collector.
Patent NZ-542815-A (NZ)
Title: 4,4-Difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or salt thereof
Inventor: KOSHIO HIROYUKI
IPC: A61P43/00
Filed: 2004-04-26
Abstract: Disclosed is a compound of formula (I), wherein the substituents are as defined in the specification. The compounds are 4,4-Difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivatives useful in the treatment of nocturia and diabetes insipidus.
Patent NZ-543795-A (NZ)
Title: A method for monitoring the stay time in a restricted conduit
Inventor: SKOGLUND TOMAS
IPC: G01F1/7084
Filed: 2003-12-22
Abstract: A method for monitoring the stay time of a product in a holding tube (1) is disclosed, whereby: (a) a first measurement registration, by temperature gauge (2), takes place at the beginning of the holding tube (1), and (b) a second measurement registration, by temperature gauge (3), takes place at the end of the holding tube (1). The measurements take place inside the holding tube (1) and the first measurement registration x measures a chemical or physical magnitude, and the second measurement registration y measures the same chemical or physical magnitude, where a best co-variation between x and y is sought, and that a time lag r at the best co-variation gives the stay time.
Patent NZ-546238-A (NZ)
Title: Method for improving steering performance in vehicle with hydraulic power steering by increasing bore size of at least a part of the flow path from pump to steering unit
Inventor: DENNIS KENNETH JOHN
Filed: 2006-03-28
Abstract: Disclosed is a method of improving steering performance of a vehicle with a hydraulic power steering system, the vehicle typically being a truck. The method consists of exchanging or permanently modifying at least one component in the flow path between pump 3 and steering unit 5, so that the size of the flow path is increased. Typically, substituting a fitting 37 that connects the flow path line 4 to the steering unit with a larger bore size fitting is stated to provide the improvement. Tests are disclosed indicating that momentary pressure surges associated with standard systems (as measured at each of the pressure pump outlet and steering unit inlet) are stated to be considerably reduced by such enlargement of flow path, stated to result in better steering performance.