baber/WOPTO huggingface dataset:
Patent DE-69115254-D1 (DE)
Inventor: PAULSON RICHARD
IPC: B26D7/12
Filed: 1991-03-07
Granted: 1996-01-18
Abstract: An apparatus for providing longitudinal, laterally spaced slits in a continuously moving sheet or web of corrugated paperboard (13) or the like includes a plurality of upper tool heads (12) each supporting a thin, circular rotary slitting blade (25). The blades (25) are coaxially mounted and driven by a common drive shaft (23) and each blade-carrying tool head (12) is independently positionable across the width of the paperboard sheet (13). Each slitting assembly includes a lower tool head or counterhead (28) carrying a roller assembly (32) which supports the underside (27) of the moving board (13) and provides a firm surface to support the board (13) against the upper rotary slitting blade (25). The roller assembly (32) includes a circumferential radially extending slot (44) in its outer surface through which an edge portion of the upper cutting blade (25) travels with the sheet firmly supported by the roller surfaces on each side of the slot (44). A blade lubricator (61) is attached to the upper head (12) and applies a thin film of lubricant to the blade edge (67) by direct engagement by a lubricating wick (65) while the blade (25) is rotating. The thin blade (25) is maintained in a sharpened condition by periodic engagement with a rotary sharpening tool (73) pivotally attached to the upper tool head (12) for periodic light sharpening contact with one face of the beveled blade cutting edge (67). Both the blade lubricator (61) and the blade sharpener (73) are retractable to inoperative positions to facilitate blade changing or blade reversal to provide extended blade life through periodic sharpening of the opposite blade edge bevel. The overlapping contact between the portion of the slitting blade (25) extending into the slot (44) in the lower supporting roller assembly (32) allows the lower tool head (28) and roller assembly (32) to be translated across the width of the sheet (13), as for repositioning, with a single positioning motor assembly (87) on the upper tool head (12).
Patent DE-69120969-D1 (DE)
Inventor: HUME ROGER ALAN
IPC: H01R33/06
Filed: 1991-08-22
Granted: 1996-08-22
Abstract: PCT No. PCT/GB91/01422 Sec. 371 Date Dec. 6, 1993 Sec. 102(e) Date Dec. 6, 1993 PCT Filed Aug. 22, 1991 PCT Pub. No. WO92/14967 PCT Pub. Date Sep. 3, 1992A lamp assembly comprises a lamp having a plurality of terminal pins projecting from a base, and a lamp holder having terminal contacts for engaging the pins. The lamp is first located in the holder by inserting the pins into respective openings in a base of the holder, and the lamp is then rotated relative to the holder to bring a portion of each pin into contact with a respective terminal contact of the holder.
Patent DE-69127197-D1 (DE)
Inventor: ROSENBERG LIOR
IPC: A61M27/00
Filed: 1991-10-03
Granted: 1997-09-11
Abstract: A fluid drain for wounds includes a tube (2) having one end insertable under the patient's skin into the wound, with the opposite end of the tube extending externally of the patient's skin; and a valve assembly (18) at the opposite end of the tube (2). The valve assembly (18) includes a first port (31) for connection to a vacuum source, a second port (32) connected to the opposite end of the tube (2), a third port (33) for outletting the drained fluid into a container, a first one-way valve permitting the fluid to flow freely therethrough only from the second port (32) to the first port (31), and a second one-way valve permitting the fluid to flow freely therethrough only from the first port (31) to the third port (33). <IMAGE>
Patent DE-69130334-D1 (DE)
Inventor: BROCK EDDIE M
IPC: F23Q3/00
Filed: 1991-12-24
Granted: 1998-11-12
Abstract: A sealed gas burner assembly comprises a burner head having a wall 23. A range top includes a well 69 and at least one burner opening formed in the well defined by an upstanding vertical flange 73. Cooperating means 75,81 are carried by the burner head and the upstanding vertical flange 23 to permit a twist lock detachable engagement between the head and flange.
Patent DE-69132494-D1 (DE)
Inventor: ABELE G
IPC: H01F7/02
Filed: 1991-02-20
Granted: 2001-01-18
Abstract: A permanent magnetic structure comprising a cylindrical body (15) and a termination structure (14, 12, 10). The cylindrical body (15) is composed of magnetic material causing a magnetic field and flux of magnetic induction. The cylindrical body (15) is oriented such that the interface between the cylindrical body 15 and the termination (14, 12, 10) is parallel to the magnetic induction and the cylindrical body (15).
Patent DE-69201857-D1 (DE)
Inventor: DUCKWORTH RALPH MARSLAND
IPC: A61K8/65
Filed: 1992-12-07
Granted: 1995-05-04
Abstract: The present invention relates to oral hygiene products in the form of liquid mouthwash compositions which comprise a particulate therapeutic agent which is stably suspended in the liquid mouthwash compositions. It has now been found that a single system can be obtained by stably suspending the particulate therapeutic agent in a liquid medium which contains specific polymers, which are selected from the group consisting of proteinaceous polymers, polysaccharidic polymers, copolymers of vinylpyrolidone with an acrylic monomer, and mixtures thereof, said polymers having an average molecular weight of 1,000,000 or less. Typical examples of suitable polymers are gelatin and Polymer JR, and a typical example of a suitable particulate therapeutic agents is magnesium fluoride.
Patent DE-69204743-D1 (DE)
Inventor: RUIGT GERARDUS STEPHANUS FRANC
IPC: C07C213/00
Filed: 1992-05-25
Granted: 1995-10-19
Abstract: The invention concerns a phenoxyphenyl derivative having the formula   <CHEM>  wherein  R is one or two halogen atoms; and A is CH2NR1R2 or 4,5-dihydro-1H-imidazole, in which R1 and R2 are independently selected from hydrogen and lower alkyl; or  a pharmaceutically acceptable salt thereof. The compounds have long half-lives and can be used against depression.
Patent DE-69213159-D1 (DE)
Inventor: BURBA JOHN
IPC: C01F7/784
Filed: 1992-04-16
Granted: 1996-10-02
Abstract: Adducts of clay, especially of the smectite variety, most especially bentonite, are prepared with an effective amount of at least one activated mixed metal oxide or oxy-hydroxide (AHMMO) formed by dehydrating hydrotalcite or a mixture comprising magnesium oxide and aluminum oxide, or a crystalline mixed metal hydroxide conforming substantially to the formula LimDdT(OH)(m+2d+3+n.a)(An)a. xH2O where m is zero to one, D is a divalent metal, d is from zero to 4, T is a trivalent metal, A represents at least one anion or negative-valence radical of valence n, where n is 1 or more, (m+2d+3+n.a) is equal to or greater than 3, (m+d) is greater than zero, and xH2O represents excess waters of hydration. These adducts are useful, e.g., in drilling muds and in viscosity modification of a wide variety of fluids.
Patent DE-69217765-D1 (DE)
Inventor: DEN DOPPER ROLF ARTHUR
IPC: B23K1/08
Filed: 1992-07-28
Granted: 1997-04-10
Abstract: The invention relates to a soldering device comprising:     a solder tower; transporting means for carrying the objects for soldering along the upper part of the solder tower; means for causing a solder wave to issue from the solder tower, which wave comes into contact with the under-side of the objects for soldering, wherein feed means are arranged for supplying gas substantially excluding oxygen to the direct vicinity of the solder wave generated by the solder tower.   Using this device the gas substantially excluding oxygen is only supplied to the place where the soldering process is taking place so that the quantity of supplied gas is limited. According to a preferred embodiment secondary feed means are arranged to supply gas substantially excluding oxygen to the vicinity of the solder tower. Dispersal of the gas supplied directly to the soldering location is hereby prevented. <IMAGE>
Patent DE-69225961-D1 (DE)
Title: Ion-sensible farbstoffe
Inventor: MOORE CHRISTOPHER PETER
IPC: C09K3/00
Filed: 1992-12-14
Granted: 1998-07-23
Abstract: The invention provides compounds represented by formula (I), wherein Y is -(CH2)2[O(CH2)2]n- in which n is an integer from 1 to 6; Z is -N=N-Ar in which Ar is a substituted or unsubstituted aryl group; Q is hydrogen or an alkyl group having from 1 to 4 carbon atoms; each R independently is hydrogen or a substituent free of acidic protons; and X is R or Z. The compounds are ion-sensitive dyes suitable for use in optical ion sensors.
Patent DE-69228923-D1 (DE)
Inventor: HLASTA DENNIS JOHN
IPC: C07D417/12
Filed: 1992-12-23
Granted: 1999-05-20
Abstract: 4-R<4>-R<5>-2-Saccharinylmethyl heterocyclic carboxylates, having the formula: <CHEM>  wherein: Het is a 5- or 6-membered monocyclic heterocycle or a 9- or 10-membered bicyclic heterocycle containing from 1 to 2 heteroatoms selected from oxygen, nitrogen and sulfur or said heterocycles substituted by from one to three, the same or different, members of the group consisting of lower-alkyl, perfluorolower-alkyl, lower-alkoxy, oxo, phenyl, halogen, and -O-(C2-C10 alkylene)-N=B where N=B is dilower-alkylamino, 1-pyrrolidinyl, 1-piperidinyl, 4-morpholinyl, 1-piperazinyl, or 4-lower-alkyl-1-piperazinyl; R<4> is hydrogen, halogen , lower-alkyl, perfluorolower-alkyl, perchlorolower-alkyl, lower-alkenyl, lower-alkynyl, cyano, carboxamido, amino, lower-alkylamino, dilower-alkylamino, lower-alkoxy, benzyloxy, lower-alkoxycarbonyl, hydroxy or phenyl; and R<5> is hydrogen or from one to two substituents in any of the 5-, 6- or 7-positions. The compounds of the present invention inhibit the activity of serine proteases, specifically human leukocyte elastase and the chymotrypsin-like enzymes, and are thus useful in the treatment of degenerative disease conditions such as emohysema, rheumatoid arthritis, pancreatitis, cystic fibrosis, chronic bronchitis, adult respiratory distress syndrome, inflammatory bowel disease, psoriasis, bullous pemphigoid and alpha-1-antitrypsin deficiency.
Patent DE-69229004-D1 (DE)
Inventor: DIZEREGA GERE
IPC: A61K38/39
Filed: 1992-11-06
Granted: 1999-05-27
Abstract: Compositions and methods for prevention of adhesion formation, whereby an effective amount of one or more adhesion preventing RGD-containing peptides is administered for a period of time sufficient to permit tissue repair. The RGD-containing peptide is further characterized in that it inhibits platelet aggregation and does not induce inflammation or trauma at the site of administration. The RGD-containing peptide is preferably administered in conjunction with a delivery vehicle (e.g., microcapsules, microspheres, liposomes, viscous instillates and absorbable mechanical barriers) useful for maintaining local concentrations of the peptide at an effective level.
Patent DE-69231280-D1 (DE)
Inventor: REED MICHAEL JOHN
IPC: C07J41/00
Filed: 1992-08-28
Granted: 2000-08-24
Abstract: The present invention provides a pharmaceutical composition comprising a compound admixed with a pharmaceutically acceptable diluent or carrier; wherein the compound has the the formula wherein each of R<sub>1</sub> and R<sub>2</sub> is independently selected from H, alkyl, alkenyl, cycloalkyl and aryl; and wherein the compound is an inhibitor of an enzyme having steroid sulphatase activity (E.C.3.1.6.2); wherein if the sulphamate group on the compound were to be replaced with a sulphate group to form a sulphate compound and incubated with a steroid sulphatase enzyme (E.C.3.1.6.2) at a pH 7.4 and 37°C it would provide a K<sub>m</sub> value of less than 50 µM; and wherein at least one of R<sub>1</sub> and R<sub>2</sub> is H.
Patent DE-69233468-D1 (DE)
Inventor: HARDY JOHN ANTHONY
IPC: C12Q1/68
Filed: 1992-01-21
Granted: 2005-02-17
Abstract: Model systems of Alzheimer's disease comprise a DNA sequence encoding an amyloid precursor protein (APP) isoform or fragment that has an amino acid substitution. The substituted amino acid may be other than valine at the amino acid position corresponding to amino acid residue position 717 of APP770. Methods of determining genetic predisposition to Alzheimer's disease are also disclosed.
Patent DE-69300192-D1 (DE)
Inventor: MATTSON RONALD J
IPC: C07D215/12
Filed: 1993-03-09
Granted: 1995-07-20
Abstract: Novel piperazinyl - and piperidinyl cyclohexenes which conform to the formula <CHEM> wherein R1 is H, C1-4 alkyl, C1-4 alkoxy, C1-4 trihaloalkyl or halogen;  X is an aryl or heteroaryl group;  n is 0,1,2, or 3; Cy is a 1-cyclohexene or cyclohexane residue, with the C=C of the cyclohexene group linked to X;  Y is N or CH;  R2 and R3 are H or C1-4alkyl; and  Ar is a substituted or unsubstituted phenyl or a heteroaryl group are useful in the treatment of ischemia-induced disorders, eg., stroke, and for the treatment of psychosis.
Patent DE-69308995-D1 (DE)
Inventor: STRAND MILES ETHAN
IPC: F16F13/20
Filed: 1993-11-24
Granted: 1997-04-24
Abstract: A bush type mounting device (10) having outer (12) and intermediate (14) sleeves, an inner metal portion (16) and a rubber spring (18) between the inner metal and the intermediate sleeve. The device has an inertial damping channel (24) in an annular space between the outer sleeve and the intermediate sleeve. Damping decoupling is provided by a decoupling plate (26) which extends radially outward from the intermediate sleeve in close association with a holding means (28). <IMAGE>
Patent DE-69310906-D1 (DE)
Inventor: SUMMERVILLE DON
IPC: G09F13/04
Filed: 1993-02-01
Granted: 1997-06-26
Abstract: A lattice type carrier for separate product identification labels and package size/price labels. The carrier is secured to the back of a vandal resistant front selection panel having one or more transparent windows for the labels mounted on the carrier. The carrier, moreover, includes an arrangement of generally rectangular frame type openings wherein translucent product identification labels are mounted and back lighted. Also, the package size/price labels may either be mounted in relatively smaller frame type openings in the carrier above the respective product identification labels or adhesively mounted to the front surface of the carrier or above the product identification areas.
Patent DE-69329494-D1 (DE)
Inventor: NAGARAJA G
IPC: C12P21/04
Filed: 1993-06-22
Granted: 2000-11-02
Abstract: A method is provided for the enhanced elaboration of leukotoxin from F. necrophorum, and subsequent production of an inactivated leukotoxoid ruminant animal vaccine against F. necrophorum infection and consequent liver abscesses and/or foot rot in such animals. The method involves forming a culture of F. necrophorum bacteria in growth media, allowing the bacteria to grow therein and to simultaneously elaborate leukotoxin in a supernate; the culturing is preferably carried out at a temperature of from about 35 DEG -41 DEG  C., a pH of from about 6.5-8, and for a period of from about 4-9 hours. At the end of the culturing, bacterial growth and leukotoxin elaboration are terminated, preferably by separating the leukotoxin supernate, whereupon the vaccine is produced by inactivation of at least the supernate.
Patent DE-69402164-D1 (DE)
Inventor: SAMAIN HENRI
IPC: A61K8/22
Filed: 1994-11-14
Granted: 1997-04-24
Abstract: The invention relates to a process for the bleaching of keratinous fibres, which consists in bringing keratinous fibres, to which a bleaching composition containing at least one oxidising agent has been applied, into contact with a gas containing water vapour, the temperature of the aforementioned gas being above 75 DEG C and the contact time between the aforementioned gas and the aforementioned fibres to be bleached being less than ten minutes. A rapid bleaching is obtained which does not give rise to any auburn glint.
Patent DE-69407174-D1 (DE)
Inventor: BAKER RAYMOND
IPC: C07D401/12
Filed: 1994-03-14
Granted: 1998-01-15
Abstract: PCT No. PCT/GB94/00504 Sec. 371 Date Dec. 29, 1995 Sec. 102(e) Date Dec. 29, 1995 PCT Filed Mar. 14, 1994 PCT Pub. No. WO94/21630 PCT Pub. Date Sep. 29, 1994Disclosed is a class of 1H-indazole derivatives, substituted at the 3-position by a substituted piperazinylmethyl moiety, which are antagonists of dopamine receptor subtypes within the brain, having a selective affinity for the dopamine D4 receptor subtype over other dopamine receptor subtypes, and are accordingly, of benefit in the treatment and/or prevention of psychotic disorders, such as schizophrenia, while manifesting fewer side-effects than those associated with classical neuroleptic drugs.
Patent DE-69412085-D1 (DE)
Inventor: BRAYER JEAN-LOUIS
IPC: C07B61/00
Filed: 1994-04-14
Granted: 1998-09-03
Abstract: PCT No. PCT/FR94/00418 Sec. 371 Date Oct. 3, 1995 Sec. 102(e) Date Oct. 3, 1995 PCT Filed Apr. 14, 1994 PCT Pub. No. WO94/24085 PCT Pub. Date Oct. 27, 1994A method for prerparing compounds of formula (I), wherein R is an optionally substituted alkenyl or alkynyl radical having up to 8 carbon atoms, or an optionally substituted mono- or polycyclic aryl or heteroaryl radical, and R1 and R2 are an alkyl radical having up to 4 carbon atoms. According to the method, a compound of the formula (II), wherein X is a halogen atom, is exposed to an organometallic compound of the formula (III): RZ, wherein R has the same meaning as before and Z is a metal or metal derivative. Alternatively, a compound of formula (II'), wherein Z' is a metal or metal derivative, is exposed to a compound of the formula (III'): RX', wherein X' is a nucleophilic reaction leaving group.    <IMAGE>  (I)   <IMAGE>  (II)   <IMAGE>  (II1)
Patent DE-69412895-D1 (DE)
Inventor: LE PELTIER FABIENNE
IPC: C10G35/09
Filed: 1994-04-25
Granted: 1998-10-08
Abstract: Process for hydroreforming in the presence of a catalyst including at least one refractory inorganic support, platinum, optionally at least one metal of group VIII, a halogen (palladium, nickel and ruthenium) and at least one additional metal M chosen from germanium, tin, lead, gallium, indium and thallium, in which process the said metal M is introduced, in the form of at least one organic compound, in situ into the reactor where the hydrocarbon feedstock will be subsequently treated or into a prereactor connected to the said reactor.
Patent DE-69414405-D1 (DE)
Inventor: PON DOUGLAS
IPC: G01N33/66
Filed: 1994-08-30
Granted: 1998-12-10
Abstract: A method for the rapid estimation of hyperplastic and hypertrophic changes in animal airways is an assay which specifically measures acidic and neutral mucoproteins in a linear fashion from 0.5 to at least 10  mu g. The assay comprises exposure of a test animal to a suspected metaplastic inducer, removal of the lungs, homogenization in an appropriately buffered solution containing reducing agents and protease inhibitors; removal of particulate matter; and size-fractionation of the SDS treated soluble extract. The high molecular weight material is immobilized and stained for either acidic or neutral mucosubstances and the specific staining is quantitated. The changes observed are consistent with those seen in histological sections of the exposed tissues. The assay is useful in confirming the metaplastic potential of suspected compounds, in determining what neurohumoral mediator(s) are involved in mucus cell metaplasia in animal models for chronic obstructive pulmonary disease, and in identifying compounds which might ameliorate these effects.
Patent DE-69428278-D1 (DE)
Inventor: POSTON ROBIN
IPC: A61K38/00
Filed: 1994-06-14
Granted: 2001-10-18
Abstract: This invention provides a method of assaying leukocyte binding to vascular tissue which comprises contacting a suspension of a monocyte-like cell line in a suitable medium with a human vascular tissue sample at a temperature of at least 10 DEG  C., and quantitating the number of bound monocyte-like cells over a defined area of tissue sample. The assay allows agents which inhibit binding of monocytes to human vascular tissue to be identified and the invention also relates to the use of such agents in the therapy of atherosclerosis.
Patent DE-69509339-D1 (DE)
Inventor: RODRIGUEZ CARMEN L
IPC: C07C309/44
Filed: 1995-09-28
Granted: 1999-06-02
Abstract: Epoxides are produced by an integrated process involving molecular oxygen oxidation of an alkylammonium salt of a sulfonic acid-substituted anthrahydroquinone, epoxidation of an ethylenically unsaturated substrate using the hydrogen peroxide-containing product obtained by such oxidation in the presence of a titanium silicalite catalyst, and regeneration of the anthrahydroquinone by hydrogenation of the anthraquinone co-product. Oxidation and epoxidation may be performed concurrently. The alkylammonium salts have the advantage of being highly soluble in polar protic media such as water and lower alcohols. The molecular oxygen oxidation of the alkylammonium salt to form an oxidation product comprising hydrogen peroxide is also claimed as also are certain novel alkyl ammonium salts of sulfonic acid-substituted anthrahydroquinone and anthraquinone.
Patent DE-69517392-D1 (DE)
Inventor: HAMMARSTEDT CURT LENNART
IPC: E03D1/35
Filed: 1995-11-24
Granted: 2000-07-13
Abstract: In the present invention, use is made of a flushing device which permits flushing with two different amounts of flushing fluid. The bottom valve member (21) of the device comprises two float rods (30, 31) which are each connected to a float (32, 33). The float rod (30) for the small flushing amount is fixedly connected to the bottom valve member, whereas the float rod (31) for the large flushing amount is connected to the bottom valve member via a lost-motion coupling (37) to make it possible for the bottom valve member to move upwards and downwards relative to this float road. In the resting position, the float rod (31) for flushing with the large amount of flushing fluid is locked by means of a lock (59), such that the float (33) connected to this float rod does not affect the lowering of the bottom valve member (21) towards its valve seat (20) during flushing. The flushing with the small amount of flushing fluid will thus be determined completely by the movements of the other float rod (30) and its associated float (32). When releasing the mechanism for flushing with the small amount of flushing fluid, a release member (55) is actuated, which first releases the above-mentioned lock (59) and then raises the bottom valve member (21) from its seat (20) by means of the float rod (31) intended for the large flushing amount. <IMAGE>
Patent DE-69521854-D1 (DE)
Inventor: OTA KIYOSHI
IPC: H04N19/00
Filed: 1995-09-04
Granted: 2001-08-30
Abstract: There is provided a method and apparatus for reproducing data which allow a reduction in the time required for recovery from the occurrence of an error. In a method and apparatus for reproducing data wherein data read from a disc is demodulated and written in a memory and data read from the memory is decoded to reproduce the original data by employing an arrangement wherein data is recorded in the disc on a sector basis; sector information associated with the sectors of demodulated data is detected; and writing and reading operations on the memory means are controlled based on the detected information. Control over the memory and distribution of data is performed on the basis of units (sectors) for data access to a disc. Therefore, even if the synchronization of data at the distribution device and decoder is disturbed, the synchronization on a sector basis can be recovered. <IMAGE>
Patent DE-69529259-D1 (DE)
Inventor: DENIS MICHEL
IPC: G01F1/115
Filed: 1995-10-09
Granted: 2003-02-06
Abstract: The liq. passing through a measuring and transmitting unit (1) rotates a propeller (3) about an axis (4) parallel to the direction of flow (F). A magnet (31) on one of the propeller blades produces a signal in a coil (51) of a sensor (5) at each revolution. The characteristics of the particular measuring and transmitting unit (1) are stored in a memory (9). The memory (9) and sensor (5) are connected to a remote electronic unit (7). This unit has a dialogue module (11) which imports the transmitter characteristics from the memory (9) for use in the remote electronic unit (7).