baber/WOPTO huggingface dataset:
Patent DK-1149111-T3 (DK)
Inventor: BROOKS PETER
IPC: A61P17/02
Filed: 2000-01-06
Granted: 2009-12-14
Abstract: The invention describes methods for inhibiting angiogenesis in a tissue by administering an antagonist that specifically binds to a proteolyzed or denatured collagen but not to native triple helical forms of the collagen. Antagonists of the invention can target, for example, denatured collagens type-I, type-II, type-III, type-IV, type-V and combinations thereof. Methods utilizing such antagonists for therapeutic treatment of tumor growth, tumor metastasis or of restenosis also are described, as are methods to use such antagonists as diagnostic markers of angiogenesis is normal or diseased tissues both in vivo and ex vivo. Antagonists include monoclonal antibodies referred to as HUI77, HUIV26, and XL313.
Patent DK-1114819-T3 (DK)
Inventor: PEARLMAN BRUCE A
IPC: C07D521/00
Filed: 1997-03-28
Granted: 2008-04-14
Abstract: A 5-aminomethyl-substituted oxalidine amide is prepared by reacting a 5-hydroxymethyl-substituted oxazolidinone alcohol with a sulfonylating agent, and reacting the resultant oxazolidinone sulfonate ammonia. The sulfonates are new conpounds.
Patent DK-1390703-T3 (DK)
Inventor: BABKES MITCHELL
IPC: G01K1/08
Filed: 2002-03-28
Granted: 2005-11-14
Abstract: An improved electronic thermometer for rectal, oral, and axillary temperature measurements includes a removable module that houses a temperature sensitive probe and isolation chamber as well as a supply of clean, uncontaminated disposable probe covers on a single color coded module. Each removable module is interchangeably operable with a single temperature calculating unit. This thermometer design reduces the risk of patient exposure to all of the common sources of contamination encountered in the use of electronic thermometers by isolating the probe, the isolation chamber, and a supply of disposable probe covers on one dedicated removable module.
Patent DK-1427396-T3 (DK)
Inventor: TRUOG PETER
IPC: A61P13/08
Filed: 2002-09-04
Granted: 2010-05-25
Abstract: A pharmaceutical unit dosage form comprising a therapeuically effective dose of a 4-phenylbutyric acid salt having prolonged release of the active ingredient, being suitable for alleviating and curing various diseases upon once or twice daily oral administration, a method of preparation of said pharmaceutical formulation and the use thereof for the treatment of benign prostate hyperplasy, cancer, leukemias, cystic fibrosis, AàIDS, kidney and liver diseases, thalassemia and urea cycle disorders comprising the twice-daily oral administration of a therapeutically effective dosage thereof to a patient.
Patent DK-1468065-T3 (DK)
Inventor: HUBER WOLFGANG
IPC: C23G1/26
Filed: 2002-12-18
Granted: 2006-12-11
Abstract: External cleaner for transport means contains: (1) tertiary amine oxide(s) (I) with one 8-18 carbon (C) alk(en)yl, alkoxypropyl or alkenylamidoalkyl group and 2 groups selected from lower alkyl, hydroxyethyl and hydroxypropyl; and (2) alkali metal salt(s) (II) of polyaspartic and/or polyglutamic acid of molecular weight 5000-50000 in a (I):(II) weight ratio of (10-3000):1.  External cleaner for means of transport contains: (1) tertiary amine oxide(s) of formula (I); and (2) alkali metal salt(s) (II) of polyaspartic and/or polyglutamic acid of molecular weight 5000-50000, in a (I):(II) weight ratio of (10-3000):1. R1R2R3NO   (I) R1  = 8-18 carbon (C) alk(en)yl, alkoxypropyl or alkenylamidoalkyl; and R2, R3 = lower alkyl, hydroxyethyl or hydroxypropyl.
Patent DK-1478360-T3 (DK)
Inventor: GORDON JOHN
IPC: A61K31/00
Filed: 2003-02-03
Granted: 2009-07-13
Abstract: The present invention relates to a method of inducing cell death in a neoplastic cell expressing a serotonin transporter (SERT) such as Burkitt's lymphoma cell or a chronic lymphocytic leukaemia cell. The method comprising exposing said neoplastic cell to a therapeutically effective amount of a pharmaceutically active agent which interacts with said SERT, said therapeutically effective amount being sufficient to cause death of said neoplastic cell.
Patent DK-1565441-T3 (DK)
Inventor: VANGELISTI MANUEL
IPC: C07D213/61
Filed: 2003-11-18
Granted: 2012-06-18
Abstract: Process for the preparation of 2-aminomethylpyridine derivative of general formula (I) : <CHEM> in which :  n represents 0, 1, 2 or 3, X is halogen atom, Y may be the same or different and may a halogen atom, a halogenoalkyl, a alkoxycarbonyl or a alkylsulphonyl.
Patent DK-1440644-T3 (DK)
Inventor: HALLIDAY ANDREW
IPC: A47J36/12
Filed: 2004-01-23
Granted: 2006-07-31
Abstract: A closure mechanism for a beverage preparation machine (201) comprising a fixed lower part (255) and an upper part (256) rotatable relative to the lower part, the upper part being moveable from an open position, in which the upper part is disengaged from the lower part, and a closed position, in which the upper part is engaged with the lower part, the closure mechanism further comprising a clamping lever (280) operable to retain the upper part in the closed position, wherein the clamping lever comprises a first member (281) being pivotably connected at a first pivot (283) to the upper part (256) and a second member (282) having a first end pivotable about a second pivot (285), an end of the first member (281) and a second end of the second member (282) being pivotably connected together at a third pivot (286) such that the clamping lever has first and second positions of stability, wherein on operation of the clamping lever to move the upper part from the open position to the closed position the clamping lever moves from the first to the second position of stability. <IMAGE>
Patent DK-1615651-T3 (DK)
Inventor: BOMBARDELLI EZIO
IPC: A61K8/37
Filed: 2004-03-23
Granted: 2011-10-24
Abstract: The invention relates to a process for cosmetic treatment, including the reduction of superficial and deep wrinkles, using ferutinine from Ferula spp extracts.
Patent DK-1680503-T3 (DK)
Inventor: JENSEN EJNER BECH
IPC: A23K20/195
Filed: 2004-09-13
Granted: 2011-10-03
Abstract: The invention relates to the use of co-expression of an antimicrobial agent and an enzyme, with a view to improving yield and/or overall production economy. Examples of antimicrobial agents are antimicrobial peptides such as lactoferricins and antimicrobial enzymes such as lysozyme and glucose oxidase, and examples of enzymes are endoglucanase, xylanase, phytase, protease, galactanase, mannanase, dextranase, alpha-galactosidase, pectate lyase, alpha-amylase and glucoamylase. A fusion product comprising the antimicrobial agent and the enzyme and a cleavable linker is novel, and can be used in animal feed and animal feed additives. The invention also describes the use of a protection domain wherein at least 50% of the amino acid residues comprised in the peptide protection domain are D (Asp) and/or E (Glu). The protection or quenching domain serves to temporarily and reversibly inactivate the antimicrobial peptide during the expression.
Patent DK-1635651-T3 (DK)
Inventor: WEDEKIND KAREN J
IPC: A23K1/165
Filed: 2004-06-18
Granted: 2011-05-23
Abstract: Dietary compositions and methods for restoring normal thyroid function in a feline having hyperthyroidism to a more nearly normal state are disclosed. The compositions and methods restrict the amount of iodine intake in the feline.
Patent DK-1702981-T3 (DK)
Inventor: WATANABE MANABU
IPC: C12N9/42
Filed: 2004-12-07
Granted: 2011-10-17
Abstract: A method for suppressing a reduction in an endoglucanase activity in the presence of a surfactant, characterized by modifying a protein having the endoglucanase activity in which the N-terminus is an amino acid other than pyroglutamic acid, to a protein having the N-terminus of pyroglutamic acid, is disclosed. Further, a modified protein having an endoglucanase activity wherein the N-terminal amino acid is converted into pyroglutamic acid by an amino acid modification, a polynucleotide encoding the protein, an expression vector comprising the polynucleotide, a host cell transformed with the expression vector, and a process for producing the protein by cultivating the host cell, are disclosed.
Patent DK-1861303-T3 (DK)
Inventor: PAOLACCI MARCO
IPC: B61L27/00
Filed: 2005-11-29
Granted: 2009-11-16
Abstract: An apparatus, and related method, for monitoring and controlling the traffic of transport systems, such as railway vehicles, wherein the vehicles include device elements, such as satellite positioning systems, monitored by a series of centralized units to monitor and control adjacent areas. In case of anomalous traffic situations, the system and method provides proper alarm signals and signals for automatically putting into action the breaking systems of the vehicles. To do so, the devices can interface with breaking means and sensors placed along the railway paths and in the vehicles, and exchange positioning data or other kinds of data of various sensors, among vehicles running within a certain mutual distance and can further include a secured memory means for storing data, information and parameters.
Patent DK-1764281-T3 (DK)
Inventor: YANG CHENG-FAN
IPC: B62B7/14
Filed: 2006-08-28
Granted: 2011-03-21
Abstract: A baby stroller frame with a seat direction changing mechanism comprising a wheeled support frame, a seat support, a handle bar and a releasing mechanism. The wheeled support frame comprises a front leg, a rear leg and wheel sets. The upper portion of the wheeled support frame has a axle hole for pivotally connecting the seat support and allows the seat support rotatably to change its direction. The angle positioning of the seat support is lockable and releaseable by driving a locking member in a locking position. The releasing mechanism is slidably mounted on the handle bar, and shall concomitantly pulls locking member while the handle bar is rotated by a user. While the locking member is pulled to leave the locking position, the seat support will be free to rotate and change its direction.
Patent DK-1851319-T3 (DK)
Inventor: SILLA TOOMAS
IPC: C12N5/10
Filed: 2006-02-13
Granted: 2009-07-27
Abstract: This disclosure shows that the BPV-1 E2 protein-dependent minichromosome maintenance element (MME) comprised of E2 multimeric binding sites can provide the stable maintenance replication function to the mouse polyomavirus (PyV) core origin plasmids in the presence of BPV-1 E2 protein and PyV large T-antigen (LT). MME dependent plasmids are lost with the frequency of 6% per generation. Significantly long stable maintenance replication can also be provided without selection pressure. We also demonstrate that PyV core origin maintenance function/replication activation could be provided by Epstein-Barr virus Family of repeats and EBNA1 protein. The maintenance of the Polyomavirus core origin plasmid was characterized by 13% loss of the plasmid during one cell generation in the case of EBV FR harboring plasmids. Our data clearly indicate that maintenance functions from different viruses can provide segregation/partitioning function to different heterologous origins in variety of cells and can be used in expression of gene products.
Patent DK-2025582-T3 (DK)
Inventor: KRONE BERNARD
IPC: B62D25/20
Filed: 2008-07-30
Granted: 2010-08-23
Abstract: The vehicle superstructure has cross beams that are divided into cross beams (11) without passage openings and cross beams (12) with passage openings (13). A cross beam (12) with passage opening is provided between two cross beams (11) without passage openings and forms a base segment. The base segment is foam filled with a polyurethane-foam by an injector opening. The cross beam (12) with passage openings is foam through from the plastic foam.
Patent DK-2132115-T3 (DK)
Inventor: FANDELLA SERGIO
IPC: B65G17/08
Filed: 2008-03-13
Granted: 2011-09-19
Abstract: A modular belt having plug-inserts produced from electroconductive material. The plugs may be snapped into respective holes that are preformed or machined in a standard plastic belt module. The modules may be produced from low cost materials such as polypropylene or polyacetal. The electroconductive plugs may be attached to the belt in numerous ways including, but not limited to, snap fit, gluing, screwing or direct integration by molding.
Patent DK-2969150-T3 (DK)
Inventor: SCHACHT PAUL
IPC: C11D11/00
Filed: 2014-03-03
Granted: 2018-08-06
Abstract: The present invention relates to the field of membrane separation processes and clean in place compositions for cleaning such membranes. The cleaning compositions can remove proteins, fats, and other food, beverage, and brewery based soils and offer an environmentally friendly alternative surfactant system to NPE. According to the invention, surfactants and polymers useful for this process are unpredictable and specific surfactants, polymers, and combinations of the same are disclosed for use alone, as part of a cleaning composition. Methods of use of the same are also included.
Patent DK-0470086-T3 (DK)
Inventor: TOIKKA JARMO
IPC: C07F15/02
Filed: 1990-04-09
Granted: 1995-05-29
Abstract: PCT No. PCT/FI90/00097 Sec. 371 Date Oct. 17, 1991 Sec. 102(e) Date Oct. 17, 1991 PCT Filed Apr. 9, 1990 PCT Pub. No. WO90/12801 PCT Pub. Date Nov. 1, 1990.Process for the purification of hemin by dissolving raw hemin into 1,3-dimethyl-2-imidazolidinone (DMI), the mixture is allowed to cool in order to crystallize the hemin in the form of a 1:3-adduct of hemin and DMI, whereafter the adduct obtained is split by mixing the same with warm water, a lower alcohol or in a mixture thereof, or by heating in a vacuum, and the liberated hemin is recovered. The invention also concerns a novel hemin derivative, that is the 1:3-adduct of hemin and DMI, and a process for its preparation.
Patent DK-0483224-T3 (DK)
Inventor: NAGARAJAN VASANTHA
IPC: C12N1/21
Filed: 1990-06-20
Granted: 1996-04-22
Abstract: A regulatable replicable recombinant expression vector comprises an expression element which is substantially homologous to a sucrose-regulatable expression element derived from a first Bacillus species, the vector, when containing a DNA sequence encoding a polypeptide to which the expression element is operably linked, being regulatable by sucrose and replicable when transformed into at least one Bacillus species different from the first Bacillus species.
Patent DK-0446704-T3 (DK)
Inventor: ARNOLD GERHARD
IPC: B26D3/26
Filed: 1991-02-27
Granted: 1994-08-08
Abstract: A kitchen appliance for slicing food has a slicing cylinder arranged rotatably in a housing. Material to be sliced is pressed against the slicing cylinder by means of a pusher which can be moved into a feeding chamber. The wall of the feeding chamber located at the rear in the direction of rotation of the slicing is fixed. The pusher is guided pivotably and displaceably in its vicinity. To the front it has a terminating wall which, during pressing, slides on the outside beyond the housing and completely seals the feeding chamber.
Patent DK-0479245-T3 (DK)
Inventor: HSIEH HENRY LIEN
IPC: C08F20/52
Filed: 1991-10-01
Granted: 1997-04-07
Abstract: A polymer suitable for use as an absorbent of an aqueous electrolyte solution polymer being formed by copolymerization of (a) an ampholytic ion pair monomer (b) at least one comonomer which may be acrylamide, methacrylamide, acrylonitrile and others and wherein there is further included a crosslinking agent which has at least two polymerizable olefinic functionalities wherein each of the olefinic functionalities is suitable for crosslinking with polymer chains formed from components (a) and (b) or a polymer which is a polysaccharide, polypropylene, or polyethylene onto which the comonomer is graft polymerized and with which there is further graft copolymerized the ampholytic ion pair monomer.
Patent DK-0471528-T3 (DK)
Inventor: OKANE PEARSE EDWARD
IPC: B29C51/42
Filed: 1991-08-09
Granted: 1995-12-11
Abstract: A method and apparatus for forming an article from a sheet of PET material of thickness greater than 1 mm comprises heating the PET sheet (3) to a preforming temperature of approximately 110 DEG C by heaters (19) and (20), and then forming the sheet (3) onto a heated vacuum mould (6). The sheet is retained in the mould (6) by the vacuum and the surface (4) and (5) of the sheet (3) are maintained at a temperature of approximately 160 DEG C by the mould (6) and the heater (19), respectively, until the degree of crystallisation of the sheet is in the order of 35%. <IMAGE>
Patent DK-0445044-T3 (DK)
Inventor: LAFRASSE JEAN
IPC: B21D7/022
Filed: 1991-01-17
Granted: 1993-11-22
Abstract: The machine is provided with two bending heads (9,10) both of which can be moved in the initial direction of the tube (12) to be bent and each of which is equipped with a bending tool working in a bending plane whose orientation can be varied. 
<??>At least one of the bending heads (9,10) is also moveable in a plane perpendicular to the initial direction of the tube (12) and carries means (27,29) for gripping the said tube which are offset in relation to the longitudinal axis of the head. Thus, this head may be moved away from the initial axis (11) of the tube, the associated gripping means (27,29) then coming into this axis and being able to hold the tube (12) there temporarily. 
<??>This arrangement enables very closely spaced elbows to be formed in the central region of the tube.
Patent DK-0535047-T3 (DK)
Inventor: REDWINE NONA JANE
IPC: A61F13/56
Filed: 1991-05-30
Granted: 1995-03-06
Abstract: Disclosed are indicia for use in conjunction with the core of an absorbent article, such as a sanitary napkin, disposable diaper, or adult incontinence product. The indicia are absorbent or liquid pervious to obviate reduction in the target area for loading of the absorbent core of such product. The indicia provide a means for visually indicating to the wearer incipient failure of the core when the capacity of the core may be exceeded by lateral migration of liquids deposited on the absorbent core. The indicia may be separate or integral relative to the absorbent core.
Patent DK-0504650-T3 (DK)
Inventor: WILDFEUER EBERHARD DR
IPC: B65D45/32
Filed: 1992-03-02
Granted: 1995-01-02
Abstract: The lid (1), injection-moulded for example from polyethylene, for a wide-necked drum of plastic has an outer rim (4) surrounding the drum neck (3) and an inner rim (5) extending into the drum neck. Lid outer rim (4) and lid inner rim (5) form an annular space (7), from the base of which an annular web (8) projects axially. For manufacturing the lid seal (13), the annular space (7) is exposed to an open flame to activate the surface of the annular space. Subsequently the sealing material, preferably polyurethane, is injected with a foaming machine into the base of the annular space (7), and then the lid (1) is vibrated to degas the seal (13). The sealing material consisting preferably of foamed polyurethane contains a release agent with long-term effect. 
<IMAGE>
Patent DK-0543683-T3 (DK)
Inventor: ROZIER PAUL
IPC: H01H1/58
Filed: 1992-06-26
Granted: 1997-03-03
Abstract: Multipole load break switch comprising, for each pole, an insulating bushing enclosing an evacuated bulb, the bushing including at a first end a first contact connected to a first terminal of the bulb and intended to cooperate with a first conductor, and at a second end a second contact connected to a second terminal of the bulb and intended to cooperate with a second conductor, the bushings being integral with a common metal section (4) shrouding a common shaft (38) for operating the bulbs (14) and which is actuated by a mechanism contained in a cabinet (5) integral with the section. Applications to medium-voltage cells and substations. <IMAGE>
Patent DK-0576617-T3 (DK)
Inventor: YOUNG JAMES W
IPC: A61K31/425
Filed: 1992-03-10
Granted: 1996-12-30
Abstract: Optically pure (S) metoprolol, which is substantially free of the (R) enantiomer, is a potent beta-blocker for treating myocardial infarction and for relieving the symptoms of angina pectoris, cardiac arrhythmia and hypertension in individuals. A method is disclosed utilizing the optically pure (S) configurational enantiomer of metoprolol for treating cardiovascular disorders while reducing undesirable side effects associated with the administration of beta-blockers.
Patent DK-0643701-T3 (DK)
Inventor: ROCHER JEAN-PHILIPPE
IPC: A61K8/00
Filed: 1992-05-29
Granted: 2002-04-15
Abstract: PCT No. PCT/FR92/00482 Sec. 371 Date Jan. 10, 1994 Sec. 102(e) Date Jan. 10, 1994 PCT Filed May 29, 1992 PCT Pub. No. WO92/21663 PCT Pub. Date Dec. 10, 1992.Benzimidazole derivatives having general formula (I), wherein R1 and R2 are a hydrogen atom, a lower alkyl radical, an OR4 radical, a lower fluoroalkyl radical or a halogen atom; R3 is a hydrogen atom, a lower alkyl radical, a halogen, a hydroxyl or a lower alkoxy radical having 1-6 carbon atoms; R4 is a hydrogen atom, a lower alkyl radical, a benzyl radical or a (II) radical, PO3H, SO3H or an aminoacid residue; R7 is a lower alkyl radical, a lower alkoxy radical having 1-6 carbon atoms, a -(CH2)n-COOH radical where n=1-6, or the radical (III), where r' and r'' are a hydrogen atom or a lower alkyl radical, or form, together with the nitrogen atom, a 5 or 6-membered heterocyclic ring optionally interrupted by a heteroatom; R5 and R6 are different and represent the OR8 radical or a mono or polycyclic cycloalkyl radical having 5-12 carbon atoms bound to the phenyl core by a tertiary carbon; R8 is a hydrogen atom, a lower alkyl radical, an acyl radical having 2-7 carbon atoms, a benzyl radical optionally substituted by one or more halogen atoms, or a benzoyl radical; and salts of said compounds obtained by adding a pharmaceutically acceptable acid or base. Said compounds may be used therapeutically, in particular in relation to inflammatory and/or immunoallergic conditions, and cosmetically to provide body and hair care.
Patent DK-0688611-T3 (DK)
Inventor: ZIBULLA DIPL-ING GEORG GISBERT
IPC: B05C1/10
Filed: 1994-12-23
Granted: 1996-07-08
Abstract: The bearing blocks (14-17) for the greasing rollers (11,12) and the springs (21) at both ends of the rollers, are located in rows on common column-like shafts (19). Locking devices (25) retain blocks and springs in these positions. They are moved away or towards each other due to spring action. The shafts are positioned vertically on a baseplate (23) or on a block-shaped collection tank. The locking unit consists of a plate with key-hole-shaped apertures. These are pushed over the ends of the shafts, and locked in positioned by a locking device.
Patent DK-0653489-T3 (DK)
Inventor: VERMEULEN ARNOLDUS NICOLAAS
IPC: A61K39/012
Filed: 1994-11-09
Granted: 2003-06-10
Abstract: This invention relates to novel Eimeria proteins with immunogenic properties as well as to DNA sequences encoding these proteins. These proteins can be administered to poultry thereby protecting the birds against coccidiosis. In addition the DNA encoding these proteins can be used for the preparation of a vector vaccine against coccidiosis.
Patent DK-0676973-T3 (DK)
Inventor: GYORY J RICHARD
IPC: A61N1/30
Filed: 1993-12-30
Granted: 1998-03-02
Abstract: A device for the electrically assisted delivery of a therapeutic agent is described. The device (500) comprises one or more rigid zones. The skin side of the rigid zone has a radius of curvature (520) which approximates that of the body site to which the device (500) is to be attached. <IMAGE>