baber/WOPTO huggingface dataset:
Patent DE-69534852-D1 (DE)
Inventor: RIVIER JEAN E F
IPC: A61P29/00
Filed: 1995-12-12
Granted: 2006-05-04
Abstract: Improved CRF antagonist peptides have the formula:  (cyclo 30-33)DPheHisLeuLeuArgGluVal  LeuGluNleAlaArgAlaGluGlnLeu   <IMAGE>   LeuNleGluIleIleNH2  wherein R30 is Cys or Glu; R33 is Cys, Lys or Orn; provided that when R30 is Cys, R33 is Cys and when R30 is Glu, R33 is Lys or Orn. The N-terminus may be extended by Asp-Leu-Thr. Lys may be substituted for Arg23 and its side chain connected by a lactam bridge to Glu20 to form a dicyclic peptide. Specific CRF antagonists disclosed include (cyclo 30-33) [D-Phe12, Nle21,38, Glu30, Lys33]rCRF(12-41); (cyclo 30-33) [D-Phe12, Nle21,38, Glu30, Orn33]rCRF(12-41), (cyclo 30-33) [D-Phe12, Nle21,38, Cys30,33]rCRF (12-41) and (bicyclo 20-23,30-33) [D-Phe12, Nle21,38, Lys23,33, Glu30]-rCRF(12-41).
Patent DE-69608166-D1 (DE)
Inventor: LAGARDE KONRAD CHARLES
IPC: G06F3/048
Filed: 1996-06-05
Granted: 2000-06-15
Abstract: A World Wide Web browser makes requests to web servers on a network which receive and fulfill requests as an agent of the browser client, organizing distributed sub-agents as distributed integration solution (DIS) servers on an intranet network supporting the web server which also has an access agent servers accessible over the Internet. DIS servers execute selected capsule objects which perform programmable functions upon a received command from a web server control program agent for retrieving, from a database gateway coupled to a plurality of database resources upon a single request made from a Hypertext document, requested information from multiple data bases located at different types of databases geograhically dispersed, performing calculations, formatting, and other services prior to reporting to the web browser or to other locations, in a selected format, as in a display, fax, printer, and to customer installations or to TV video subscribers, with account tracking. <IMAGE>
Patent DE-69611370-D1 (DE)
Inventor: BAXTER RONALD
IPC: B65D85/72
Filed: 1996-06-17
Granted: 2001-02-01
Abstract: A sealed, openable, pressurised liquid container comprises a bottle B partly filled with liquid to provide a headspace (22). A foam-promoting device D floats on the liquid in the bottle. The device D comprises a hollow body (10) having first and second tubes (12 and 14). The first tube (12) has an upper end in communication with the exterior of the hollow body via a restricted orifice (16) disposed in the headspace (22) in the bottle, and a lower end in communication with the interior of the hollow body (10). The second tube (14) has a lower end in communication with the exterior of the hollow body via a restricted orifice (18) disposed below the surface of the liquid (20) in the bottle B, and an upper end in communication with the interior of the hollow body (10). The lower end of the first tube (12) is disposed at a lower level than the upper end of the second tube (14). The device D is partly filled with liquid (24) to a level intermediate the levels of the lower end of the first tube (12) and the upper end of the second tube (14) so that the lower end of the first tube (12) is submerged in the liquid (24) in the device D and the upper end of the second tube (14) is disposed above the level of the liquid (24) in the device D.
Patent DE-69612756-D1 (DE)
Inventor: JOHNSON KENNETH
IPC: A61F13/72
Filed: 1996-10-01
Granted: 2001-06-13
Abstract: A flangeless seam especially useful in disposable articles, such as training pants, incontinence articles and the like. The flangeless seam preferably comprises a first member and a second member; at least a portion of the second member overlaps at least a portion of the first member. The flangeless seam preferably further comprises a barrier member disposed between at least a portion of the overlapping portions of the first member and the second member forming a laminate having a seam area. A joining means is preferably disposed in at least a portion of the seam area joining at least a portion of the first member to at least a portion of the second member, the barrier member preventing at least a portion of the first member from becoming joined with at least a portion of the second member.
Patent DE-69616811-D1 (DE)
Inventor: MATHRE J
IPC: C07D495/04
Filed: 1996-08-26
Granted: 2001-12-13
Abstract: This invention is concerned with an improved process for the synthesis of hydroxysulfone, which is a key intermediate in the synthesis of carbonic anhydrase inhibitors, especially dorzolamide. Carbonic anhydrase inhibitors are known to be effective in treating elevated intraocular pressure or glaucoma.
Patent DE-69624219-D1 (DE)
Inventor: BIANCHI CARLO
IPC: A43D119/00
Filed: 1996-03-28
Granted: 2002-11-14
Abstract: A machine for producing footwear comprises support means on which a shoe last (4) is positioned, to which is attached an insole and over which is laid an upper (6), a projector (13) that emits a beam of light (14) towards the said support means so as to mark a line of reference (15) along which the shoe last (4) and the upper (6) are centred, a set of clamps for gripping and stretching the upper (6) over the shoe last (4) and a pad (18) that can move in an approximately vertical direction towards and away from the said support means in order to hold the shoe last (4) and the upper (6) in position so that subsequent operations can be carried out on the upper (6) and on the insole. Advantageously, the projector (13) can move between a working position in which it marks the said line of reference and a retracted position when the pad (18) is holding the shoe last (4) and the upper (6) in position, so that it is out of the way of the said pad. <IMAGE>
Patent DE-69627704-D1 (DE)
Title: Protegrine
Inventor: LEHRER I
IPC: A01N63/50
Filed: 1996-05-24
Granted: 2003-05-28
Abstract: Peptide-based compounds containing four invariant cycteine residues which have been optionally oxidized to contain two intramolecular disulfide bonds, or modified forms where the cysteines are replaced are useful as preservatives and in preventing, treating, or ameliorating viral or microbial infection in animals and plants, and in inactivating endotoxin. These compounds, in one embodiment, are of the formula:   A1A2A3A4A5C6A7C8A9A10 (1)   A11A12C13A14C15A16(A17A18)  and the N-terminal acylated and/or C-terminal amidated or esterified forms thereof, which is either in the optionally -SH stabilized linear or in a cystine-bridged form wherein each of A1 and A9 is independently a basic amino acid; each of A2 and A3 is independently a small amino acid; each of A5, A7, A12, A14 and A16 is independently a hydrophobic amino acid; A4 is a basic or a small amino acid; A10 is a basic or a small amino acid or is proline; A11 is a basic or a hydrophobic amino acid; A17 is not present or, if present, is a small amino acid; A18, is not present or, if present, is a basic amino acid; or a modified form of formula (1) and the N-terminal acylated and/or C-terminal amidated or esterified forms thereof wherein each of 1-4 cysteines is independently replaced by a hydrophobic amino acid or a small amino gacid.
Patent DE-69629676-D1 (DE)
Inventor: ROSZHART TERRY V
IPC: G01C19/5656
Filed: 1996-04-23
Granted: 2003-10-02
Abstract: A solid state silicon micromachined acceleration and Coriolis (MAC) sensor that measures linear and angular motion. The MAC sensor is a single device that performs the functions of a conventional accelerometer and a gyroscope simultaneously. The MAC sensor is unique in that it is a differential dual stage device using only one micromachined proof mass to measure both linear and angular motions. The single proof mass is connected to opposing electromechanical resonators in a monolithic microstructure made from single crystal silicon. This unique design offers improvements in measurement performance and reductions in fabrication complexity that are beyond the state the art of earlier micromachined inertial sensors.
Patent DE-69714581-D1 (DE)
Inventor: KOHLI SANJAI
IPC: G01S19/22
Filed: 1997-04-25
Granted: 2002-09-12
Abstract: A terrestrial C/A code GPS receiver system digitally samples, filters and stores a segment of 11 half chips of the received composite as a binary number and multiplexes this number for parallel correlation with each of a series of multibit code replicas for the satellites to be tracked. Each of the time delay specific correlation products are accumulated in a cell of a memory matrix so that at least twenty-two delays for each satellite may be evaluated each code period providing fast reacquisition even within a city intersection, as well as correction of multipath tracking and multipath interference. All cells of the memory matrix may be used for an acquisition of a single satellite in about 4 ms. Two satellite tracking, in addition to altitude hold, uses cross-track hold alternating with clock hold to update the cross-track estimate. Single satellite tracking uses cross-track and clock hold together. Navigation data is updated with detected changes in motion including turns.
Patent DE-69717489-D1 (DE)
Inventor: DENT W
IPC: H04W88/14
Filed: 1997-09-19
Granted: 2003-01-09
Abstract: An apparatus and method for ciphering traffic exchanged in both directions between a satellite/cellular telephone and a ground station network using an orbitial satellite. A buffer memory is provided at either the mobile telephone station or the ground network station or both. The buffer memory is used to store the deciphering bits output from a duplex ciphering algorithm at the time the ciphering bits are generated. The stored ciphering bits are used to decipher a later-to-be-received traffic information block. The delay in using stored deciphering bits is determined for each call at call set-up to the nearest integer number of block periods by measuring the loop propagation delay from the ground station to the mobile telephone station during an exchange of signals at call set-up. <IMAGE>
Patent DE-69717664-D1 (DE)
Inventor: REITER ROBERT E
IPC: C07K14/705
Filed: 1997-09-05
Granted: 2003-01-16
Abstract: The invention provides a human E25a protein which is upregulated in cancerous cells, including those of hormone refractory prostate cancer, colon cancer, breast cancer or other cancers of epithelial origin. The invention also provides nucleic acid molecules encoding E25a protein, nucleic acid probes which hybridize with nucleic acid molecules encoding E25a protein, and antibodies which bind E25a protein. E25a protein and its related molecules can be useful as diagnostic markers of cancer, including hormone refractory prostate cancer, and as specific therapeutic targets in this disease. The invention also provides methods for diagnosing cancer, including hormone refractory prostate cancer.
Patent DE-69717930-D1 (DE)
Inventor: LAURES ANTOINE
IPC: H04N7/16
Filed: 1997-09-12
Granted: 2003-01-30
Abstract: The television channel recognition technique involves using a circuit (7) for extracting and sampling the video signal. This is done after the source selector, and prior to the signal being sent to the TV tube (2), via an amplifier.. The video signal digital bits are sampled, and the first and second technical messages within the bit sequences are searched. The messages are extracted using a clock frequency which is a multiple between 2 and 5 times the nominal bit transmission frequency. The recognition of the messages enables the determination of the operating channel.
Patent DE-69724935-D1 (DE)
Inventor: KRAMER G
IPC: B23D51/10
Filed: 1997-02-28
Granted: 2003-10-23
Abstract: A reciprocating saw comprising a reciprocatable spindle (44) having an end adapted to receive a saw blade (42), and a blade clamp mechanism (41) connected to the spindle (44) and adapted to attach the saw blade (42) to the spindle. The blade clamp mechanism (41) includes an actuating member (56) mounted on the end of the spindle (44), a locking member (50) operatively associated with the actuating member (56), and a biasing member (54) interconnected with the actuating member for biasing the actuating member toward an engaged position. A cover (52) encloses a substantial portion of the biasing member (54). A housing (59), made from a thermally insulative material, is mounted to the actuating member (56). An ejecting member (90) is interconnected with the spindle (44) and is capable of engaging the saw blade (42) such that the saw blade is urged away from the end of the spindle.
Patent DE-69727672-D1 (DE)
Inventor: NARBAD ARJAN
IPC: C12N15/09
Filed: 1997-03-24
Granted: 2004-03-25
Abstract: A method of producing vanillin comprising the steps of: (1) providing trans-ferulic acid or salt thereof; and (2) providing trans-ferulate; CoASH ligase activity (enzyme activity I) trans-feruloyl SCoA hydratase activity (enzyme activity II), and 4-hydroxy-3-methoxyphenyl-beta-hydroxy-propionyl SCoA (HMPHP SCoA) cleavage activity (enzyme activity III). Conveniently the enzymes are provided by Pseudomonas fluorescens Fe3 or a mutant or derivative thereof. Polypeptides with enzymes activities II and III and polynucleotides encoding said polypeptides. Use of said polypeptides or said polynucleotides in a method for producing vanillin.
Patent DE-69800814-D1 (DE)
Inventor: SUGIKAWA HIROFUMI
IPC: B22F5/00
Filed: 1998-03-11
Granted: 2001-06-28
Abstract: Metal powders (P) are spread on a feeding belt (2) or a supporting sheet which is continuously fed, the feeding belt or the supporting sheet on which the metal powders have been spread is passed through a sintering oven (4), and the metal powders are sintered, with adjacent uncompressed metal powders in contact with each other partly and gaps present therebetween. Consequently, contact portions of the metal powders are integrated with each other and the gaps are formed as fine pores. <IMAGE>
Patent DE-69812581-D1 (DE)
Inventor: CHAN ALBERT
IPC: A61F2/82
Filed: 1998-12-11
Granted: 2003-04-30
Abstract: A method for coating a substrate with a radioisotope comprising is disclosed. The method comprises immersing the substrate within a solution containing a  UPSILON ,  beta <+>,  alpha  or  beta <-> emitting radioisotope, then exposing the immersed substrate to tuned vibrational cavitation (i.e. ultrasonic) to produce a coated substrate, followed by baking the coated substrate at a temperature below the recrystallization temperature of said substrate. Following this step, the substrate is rinsed and dried. Substrates coated using the method of this invention exhibit very low rates of leaching of the coated radioisotope, and are suitable for use within medical applications.
Patent DE-69813692-D1 (DE)
Inventor: TSUKIANA TAKASHI
IPC: F01P5/06
Filed: 1998-08-07
Granted: 2003-05-28
Abstract: A construction machine having an oil cooler 3, a radiator 4, and a fan shroud 5 arranged in an upper rotating body 13, in which the oil cooler 3 and the fan shroud 5 are securely fixed to the upper rotating body 13 and the radiator 4 is adapted to be detachably fixed to the upper rotating body 13 while the oil cooler 3 and the fan shroud 5 are held in the state fixed to the upper rotating body 13. <IMAGE>
Patent DE-69815445-D1 (DE)
Inventor: LEIFELS JOACHIM
IPC: B67D7/34
Filed: 1998-07-07
Granted: 2003-07-17
Abstract: Device for connecting at least a discharge tube and return tube to a bung connection (3) of a container (1) for liquids and the like, said connection being embodied with inner screw thread, which device comprises:   a cylindrical insert (4) with screw thread (5) arranged on the cylinder outer wall and co-acting with the bung, and a bottom (8) provided with at least two openings (6,7), a tube connecting bung (11) provided with passages (12,13) for the discharge tube and return tube aligned with said openings, and a clamping piece (16) for fixing the connecting bung in the cylindrical insert via connecting means (9,22), wherein there are arranged lugs (20,21) placed in a determined pattern and recesses (23,24) receiving these lugs, wherein the clamping piece is connected non-slidably in axial direction to the bung but freely rotatable relative thereto, and wherein the connecting means (9) in the insert are arranged at a distance from the bottom in order to form a chamber (10), the recesses (23,24) are placed above the chamber in the insert and the lugs (20,21) lie on a downward extended part (19) of the clamping piece and at a distance below the connecting means (22), whereby the tube to be connected onto the container remains free of tension.   <IMAGE>
Patent DE-69816819-D1 (DE)
Inventor: RICKARD PAUL
IPC: H04B3/54
Filed: 1998-06-08
Granted: 2003-09-04
Abstract: A power line communications system has at least one power line upon which noise level varies with time. The system determines quiet periods when noise upon the line is at a reduced level and transmits one or more data packets within the quiet periods, so as to increase data throughput in the system.
Patent DE-69823032-D1 (DE)
Inventor: ZERVOUDIS JOHN
IPC: C23C2/06
Filed: 1998-05-22
Granted: 2004-05-13
Abstract: An alloy and a process for the galvanizing of steels containing silicon by an immersion galvanization process, the alloy comprising a zinc alloy of commercial purity having, by weight, aluminum in the amount of at least 0.001 %, tin in the amount of about 0.5 % to about 2 %, and one of vanadium in the amount of at least 0.02 %, preferably 0.05 % to 0.12 %, titanium in the amount of at least 0.03 %, preferably 0.06 % to 0.1 %, or vanadium with titanium in the amount of at least 0.02 % of vanadium and at least 0.01 % of titanium, for at least 0.03 %, preferably 0.05 % to 0.15, of vanadium and titanium collectively, the balance zinc containing up to 1.3 wt.% lead. This alloy can enhance zinc-nickel alloy baths containing a normal operating range of 0.05 % to 0.08 % nickel to a maximum of 0.1 % nickel. An embodiment of the allow composition for zinc-nickel alloy baths may contain vanadium with nickel in the amount of at least 0.02 % vanadium and at least 0.02 % nickel to a maximum of 0.15 % vanadium and nickel collectively. Titanium may be added in an amount of at least 0.01 % titanium to a maximum of 0.2 % vanadium, nickel and titanium. A further embodiment of the alloy composition for use in a zinc alloy bath is comprised of aluminum in the amount of at least 0.001 %, tin in the amount of about 0.5 % to about 2 %, vanadium in the amount of 0.02 % to 0.12 %, bismuth in the amount of 0.05 % to 0.5 %, preferably 0.05 % to 0.1 %, and the balance zinc. The process is suitable for galvanizing a wide range of steels including reactive steels. The maximum silicon level controlled varies from 0.5 % to 1 % depending on the combination and amounts of tin, vanadium and titanium in the alloy.
Patent DE-69824166-D1 (DE)
Inventor: LARSSON ANDERS
IPC: C07K16/02
Filed: 1998-03-20
Granted: 2004-07-01
Abstract: The present invention relates to use of avian antibodies and/or antigen binding fragments thereof, for the production of a drug for treatment and/or prevention of respiratory tract infection. The drug is administered through local application at the oral cavity and/or pharynx.
Patent DE-69830374-D1 (DE)
Inventor: ENGDAHL ERIK H
IPC: H01L21/304
Filed: 1998-11-11
Granted: 2005-07-07
Abstract: A system and method for planarizing a plurality of semiconductor wafers is provided. The method includes the steps of processing each wafer along the same process path using at least two polishing stations to each partially planarize the wafers. The system includes an improved process path exchanging a detachable wafer carrying head with spindles at each processing point and conveying the detached wafer carrying heads in a rotary index table between processing points. The system also provides for improved polishing accuracy using linear polishers having pneumatically adjustable belt tensioning and aligning capabilities.
Patent DE-69830522-D1 (DE)
Inventor: ROCHELLE ROBERT EDWIN
IPC: B65B61/18
Filed: 1998-02-20
Granted: 2005-07-14
Abstract: An apparatus and method for securing a pour spout fitment to a panel of a filled and sealed thermoplastic-coated carton, wherein a machine 10 is mounted over a conveyor 12 conveying a line of cartons. Within the machine 10, a selected panel surface of each filled and sealed carton is heated to a predetermined temperature; next, at least an annular surface of a flange of the fitment is heated to a predetermined temperature. When the heated surface of the fitment is applied to the heated surface of the carton, the heat energy is transferred to the latter surface to an extent capable of activating the thermoplastic coating thereon. Upon pressing and cooling, the fitment and the carton surface are bonded together, without the need for a back-up or support mechanism, such as a mandrel or anvil. Alternatively, the fitment may be secured to the carton by way of a jetted-on, circular bead of hot melt adhesive. <IMAGE>
Patent DE-69830981-D1 (DE)
Inventor: RAY JAMES T
IPC: F02C5/04
Filed: 1998-10-21
Granted: 2005-09-01
Abstract: A combustion engine is provided having a rotating drive shaft. A planetary gear set links a rotating chamber, keyed to the drive shaft, to turbomachinery within the chamber. Fluid is fed to the chamber through an axial passage in the drive shaft and is compressed by a number of mechanisms, including a set of combustion channels initially driven by the drive shaft and its starter motor. Bubbles within the fluid are subjected to high pressures causing combustion to occur within the bubbles. Additional pressure created by the combustion of the bubbles drives the fluid to exert a net torque on the drive shaft, thereby generating power.
Patent DE-69835207-D1 (DE)
Inventor: KWIATKOWSKI MAREK
IPC: C12Q1/6834
Filed: 1998-05-14
Granted: 2006-08-24
Abstract: A method of preparing an immobilized oligonucleotide having a free 3'-end comprises the steps of: i) preparing an oligonucleotide attached in a first position to a solid support via its 3'-end and having a free 5'-end; ii) binding said oligonucleotide in a second position remote from the 3'-end to the solid support; and iii) selectively releasing the 3'-end of the oligonucleotide from the solid support to obta the oligonucleotide attached to the support in said second position in a reversed orientation with a free 3'-end.
Patent DE-69841470-D1 (DE)
Inventor: BUNCKE HARRY J
IPC: A61B17/00
Filed: 1998-05-21
Granted: 2010-03-11
Abstract: The invention relates to a combination of a suture (10) secured to a trailing end of a surgical needle (14a,14b), where the suture comprises a multiplicity of barbs (16) on the exterior surface of the suture, the barbs being configured to engage against a patient's tissue, wherein a leading end (10a) of the suture is free of barbs in an initial region and for a selected distance (10c).
Patent DE-69900283-D1 (DE)
Inventor: MURAKAMI KAZUO
IPC: A61K38/00
Filed: 1999-10-13
Granted: 2001-10-18
Abstract: Disclosed is a novel renin-active substance by utilizing a anti-peptide antibody capable of specifically recognizing a specific amino acid sequence in the human prorenin profragment exemplified, as a typical example, by a complex formed from human prorenin and an anti-peptide antibody capable of specifically recognizing an amino acid sequence consisting of at least 15 amino acid residues located within an amino acid sequence consisting of 33 amino acid residues between the isoleucine residue at the 11th site and the arginine residue at the 43rd site within human prorenin profragment having an amino acid sequence consisting of 43 amino acid residues.