baber/WOPTO huggingface dataset:
Patent CA-2921845-C (CA)
Inventor: KIM JAE WHA
IPC: A61K31/22
Filed: 2014-08-18
Granted: 2018-07-10
Abstract: The invention relates to pharmaceutical compositions, as well as health functional food compositions and quasi-drug compositions, for preventing, treating, or improving rheumatoid arthritis, comprising a monoacetyldiacylglycerol compound as an active ingredient. The monoacetyldiacylglycerol of the invention is effective in inhibiting the phosphorylation of STAT-3 known to be a therapeutic target for rheumatoid arthritis. As the monoacetyldiacylglycerol is an effective therapeutic agent without toxicity, the monoacetyldiacylglycerol can overcome the side effects of the medicines currently used in the treatment of rheumatoid arthritis.  Thus, the monoacetyldiacylglycerol can be used for preventing, treating or improving rheumatoid arthritis.
Patent CA-2926231-C (CA)
Inventor: MAHLER MICHAEL
IPC: C07K1/107
Filed: 2015-07-22
Granted: 2022-10-04
Abstract: The present disclosure relates to the field of molecular biology and more specifically to methods for detecting anti-carbamylated protein (anti-CarP) antibodies in the serum of rheumatoid arthritis (RA) patients.
Patent CA-2928098-C (CA)
Inventor: COLEMAN JAMES E
IPC: A61F6/20
Filed: 2014-11-20
Granted: 2018-07-03
Abstract: Systems and methods are provided for using an actuator to deploy an implant configured to close a tissue puncture or a natural opening in a body. The actuator includes a handle that is rotated in a first direction to deploy a first set of deployable wings of the implant, and that is rotated in a second, opposite direction to deploy a second set of deployable wings of the implant. A guide wire coupled between the implant and the actuator rotates and/or moves axially with the actuator to cause the wings to deploy. After each of the first and second rotation strokes, the handle is prevented from rotating beyond the first and second strokes, respectively. After the wings are deployed to engage tissue therebetween, the handle is operated to eject the implant from the actuator.
Patent CA-2930579-C (CA)
Inventor: FISHER GIDON
IPC: D01F8/14
Filed: 2016-05-20
Granted: 2021-08-03
Abstract: Une méthode de fabrication de fil est décrite. Une pluralité de fibres sont obtenues par : préparation dune suspension de polymère mélangée avec des nanoparticules insolubles dans leau de cuivre électrolytique, et extrusion de la suspension à travers une filière qui comprend une pluralité de trous qui confèrent une section transversale généralement en forme de X à la pluralité de fibres. La pluralité de fibres sont tisées ensemble pour former le fil.
Patent CA-2931735-C (CA)
Inventor: DAVIS MARK PRESTON
IPC: F27D9/00
Filed: 2014-12-04
Granted: 2022-05-10
Abstract: Selon l'invention, une cuve de fusion (4) pour la production de métal en fusion comprend un creuset à chemisage réfractaire qui, en cours d'utilisation, est en contact avec du laitier en fusion ou du métal en fusion dans la cuve de fusion, le creuset comprenant une pluralité de caloducs (2.1) positionnés dans un chemisage réfractaire d'au moins une partie du creuset pour refroidir le chemisage réfractaire.
Patent CA-2932292-C (CA)
Inventor: NAKAJIMA KOTARO
IPC: B23K11/31
Filed: 2014-02-06
Granted: 2017-12-19
Abstract: A low-cost, compact rotary work device with great versatility is provided Specifically, the rotary work device includes: a first output gear into which a holder is fitted; a second output gear into which a cutter is fitted; a second intermediate gear meshing with both the output gears; and a servomotor rotating the second intermediate gear. A control panel includes a memory storing a first rotational speed and a second rotational speed that is higher than the first rotational speed. When an electrode detachment operation is performed, both the output gears are rotated at the first rotational speed, and when an electrode cutting operation is performed, both the output gears are rotated at the second rotational speed.
Patent CA-2940792-C (CA)
Title: Systems and methods for automated mapping and accuracy-testing
Inventor: MORGAN SEAN M
IPC: G01V13/00
Filed: 2016-08-31
Granted: 2019-07-16
Abstract: An apparatus for mapping and accuracy-testing an electromagnetic navigation system includes a sensor sensing electromagnetic vectors of an electromagnetic field, a carriage moving the sensor along a first direction and a second direction different from the first direction, a first position detector operatively associated with the sensor and detecting a first position of the sensor along the first direction, a second position detector operatively associated with the sensor and detecting a second position of the sensor along the second direction, and a controller operatively associated with the sensor and controlling movements of the carriage along the first and second directions and mapping the electromagnetic field based on the sensed electromagnetic vectors at predetermined positions in a coordinate system defined by the first direction, the second direction, and a third direction perpendicular to a plane defined by the first and second directions.
Patent CA-2956457-C (CA)
Inventor: MCEWAN JOHN S
IPC: E21B43/28
Filed: 2017-01-30
Granted: 2019-05-21
Abstract: Some embodiments of the present disclosure include a method and method for recovery of solution mined minerals. The method may include creating superheated steam using a steam boiler; passing the superheated steam through a turbine/generator to generate electricity; reheating the steam exiting the turbine/generator to saturation with a steam reheater; using the saturated steam with an absorption chiller to create chilled water; and recovering minerals using the chilled water in a cooling crystallizer system. In embodiments, the method and system may be used to recover minerals, such as potash (KCl), washing soda (Na2CO3.cndot.10H2O); nahcolite (NaHCO3); and glauber salt (NaSO4.cndot.10H2O). The method may utilize the trigeneration of steam, electrical, and chilled water utilities, which may be used for a recovery process.
Patent CA-2958049-C (CA)
Inventor: MARUSKO MARK WILLARD
IPC: F02C7/12
Filed: 2017-02-16
Granted: 2019-04-16
Abstract: A shroud for a gas turbine is provided. The shroud can include an outer box having a first wall and a second wall circumferentially spaced apart from the first wall. An inner box is positioned within the outer box. The inner box defines one or more passageways extending therethrough and a first chamber. The inner box and the outer box collectively define a second chamber. The one or more passageways defined by the inner box fluidly couple the first chamber and the second chamber. The first wall of the outer box defines a first boss and first notch, and the second wall of the outer box defines a second boss and notch. A gas turbine is also provided that can include a plurality of such turbine shrouds.
Patent CA-2958356-C (CA)
Title: Systems and methods of feeding hook fastening elements into a mold assembly line
Inventor: SHO YOSHIYUKI
IPC: B65H16/00
Filed: 2011-11-03
Granted: 2020-01-28
Abstract: A system for facilitating continuous feeding of hook fastening tape through the system is described. When a first of two or more spools runs out of the hook fastening tape, the system moves the end of the hook fastening tape of a second of the two or more spools along the one direction to align the end of the hook fastening tape of the second of the two or more spools with the tape feed area and pulls the hook fastening tape from the second of the two or more spools and feeds it through the system.
Patent CA-2961124-C (CA)
Inventor: KACZMAREK MICHAL
IPC: C25D3/22
Filed: 2015-10-19
Granted: 2023-09-05
Abstract: The present invention relates to an acidic zinc or zinc-nickel alloy plating bath composition comprising a source for zinc ions, optionally a source for nickel ions, a source for chloride ions and at least one dithiocarbamyl alkyl sulfonic acid or salt thereof. Said plating bath composition and the corresponding plating method result in zinc or zinc-nickel alloy layers having an improved throwing power and thickness distribution, particularly when plating substrates having a complex shape and/or in rack-and-barrel plating.
Patent CA-2971872-C (CA)
Title: Mutant idh1 inhibitors useful for treating cancer
Inventor: BOXER MATTHEW BRIAN
IPC: C07D417/14
Filed: 2015-12-22
Granted: 2023-10-10
Abstract: Compounds of Formula I and Formula II and the pharmaceutically acceptable salts thereof are disclosed The variables A, B, Y, Z, X1, X2, R1-4 and R13-18 are disclosed herein. The compounds are useful for treating cancer disorders, especially those involving mutant IDH1 enzymes. Pharmaceutical compositions containing compounds of Formula I or Formula II and methods of treatment comprising administering compounds of Formula I and Formula II are also disclosed.
Patent CA-2979617-C (CA)
Title: Grp94 derived polypeptides for inhibiting pcsk9 and methods of use
Inventor: POIRIER STEVE
IPC: C07K14/47
Filed: 2016-03-19
Granted: 2024-01-02
Abstract: The present invention relates to PCSK9 inhibitors and methods of use thereof. Specifically, the invention relates to PCSK9 cell-based assay, PCSK9 inhibiting polypeptides and derivatives thereof. The invention includes pharmaceutical compositions comprising a PCSK9 inhibitor polypeptide together with a pharmaceutically acceptable carrier and method for treating cardiovascular disorders, inflammatory diseases or inflammatory response to infection.
Patent CA-2980287-C (CA)
Inventor: FREAKE JACOB
IPC: C12M1/38
Filed: 2016-03-17
Granted: 2022-08-16
Abstract: An incubator assembly includes an incubator enclosure having an internal chamber in which a controlled environment is maintained and which is defined by one or more walls. The incubator assembly further includes a jacket assembly mounted adjacent to at least one of the walls and having an internal airspace in which an internal fluid is enclosed for maintaining a homogenous temperature within the internal chamber. The jacket assembly further has a vent movable between a plurality of positions including an open position in which the internal fluid is allowed to exit the internal airspace into an ambient environment.
Patent CA-2985561-C (CA)
Title: Device for assisting with the manual merging of postal objects into a stack of mail items
Inventor: MIETTE EMMANUEL
IPC: B07C7/00
Filed: 2016-05-30
Granted: 2019-08-13
Abstract: The invention relates to a device (1) for assisting with the merging of postal objects (2) into a stack of mail items (3) that have already been sorted according to a certain sequence, including a merging table (5) capable of storing the stack of mail items on edge, a first camera (8) capable of forming a digital image of a current postal object to be merged into the stack of mail items, a second camera (11) which observes the stack of mail items as an operator placed at one end (5A) of the merging table, and a control and command unit (13) having a display screen (10) which is placed at the end (5A) of the merging table.
Patent CA-2999004-C (CA)
Title: Vehicular display device and vehicular display method
Inventor: WATANABE HIROSHI
IPC: B60K35/00
Filed: 2015-09-18
Granted: 2021-06-15
Abstract: In execution of tracking travel control, when a preceding vehicle to be tracked is detected, a vehicular display device according to the present invention performs setting so that a fixed display which indicates that the preceding vehicle to be tracked has been detected is lit, and so that a tracking mark is displayed so as to be superposed on the preceding vehicle to be tracked. Then, images of the fixed display and the tracking mark are displayed in a display region which is provided so as to be superposed on a position of a windshield provided to a host vehicle. When a predetermined period of time has elapsed after the tracking mark is displayed, the tracking mark is turned off while the fixed display is lit.
Patent CA-2999904-C (CA)
Inventor: FENG CHAOYANG
IPC: C01B32/182
Filed: 2015-10-23
Granted: 2020-12-01
Abstract: Provided is an industrial method for preparing a large-sized graphene, which comprises the following steps: mixing a graphite with a concentrated sulphuric acid to obtain a mixed solution (a), and subjecting the mixed solution (a) to an ultrasonic treatment, a solution obtained after the ultrasound comprising an upper graphene and a lower concentrated sulphuric acid solution (b); separating the graphene from the concentrated sulphuric acid solution (b); and washing the graphene with water, filtering and drying same to obtain the large-sized graphene. The method has a good stripping effect, the obtained graphene has a large size, and the sulphuric acid, as an intercalation agent, can be repeatedly utilised. The method is environmentally friendly, saves resources and has good prospects in industrial application.
Patent CA-3002755-C (CA)
Title: Suspensions orales de givinostat physiquement et chimiquement stables
Inventor: COLOMBO GIUSEPPE
IPC: A61K9/10
Filed: 2016-10-28
Granted: 2022-10-18
Abstract: L'invention concerne des formulations orales liquides, physiquement et chimiquement stables, de Givinostat (chlorure de diéthyl-[6-(4-hydroxycarbamoyl-phénylcarbamoyloxyméthyl)-naphthalène-2-yl-méthyl]-ammonium), ainsi que des procédés pour la préparation de ces dernières. De telles formulations orales se présentent sous la forme de suspensions aqueuses et contiennent du Givinostat et/ou des sels et/ou dérivés de qualité pharmaceutique de ce dernier, au moins un agent mouillant et/ou au moins un agent conférant de la densité. Ces formulations sont appropriées pour une administration par voie orale en vue d'une action thérapeutique systémique.
Patent CA-3006928-C (CA)
Title: Rotor brake effect by using electric distributed anti-torque generators and opposing electric motor thrust to slow a main rotor
Inventor: HALDEMAN ANDREW
IPC: B64D27/24
Filed: 2018-05-31
Granted: 2019-07-16
Abstract: The present invention includes a system and method for slowing the rotation of a rotor using, for example, rotor brake system for a rotorcraft comprising: one or more generators connected to a main rotor gearbox; an electric distributed anti-torque system mounted on a tail boom of the rotorcraft comprising two or more electric motors connected to the one or more generators, wherein the two or more electric motors are connected to one or more blades; and wherein a rotation of the rotor is slowed by placing a drive load on the main rotor gearbox with the one or more generators to bleed the mechanical power from rotor into electrical power via the two or more electric motors, wherein the electric distributed anti-torque system generates thrust in opposing directions.
Patent CA-3010452-C (CA)
Inventor: COLLURA MARIANO
IPC: B22D41/22
Filed: 2017-01-24
Granted: 2023-08-29
Abstract: Une plaque de robinet-vanne à lunette réfractaire comprend une surface supérieure plane et une surface inférieure plane parallèle à la surface supérieure plane. Une surface extérieure de connexion raccorde la surface supérieure à la surface inférieure et un canal de déversement qui raccorde de manière fluide la surface supérieure et la surface inférieure. Des rapports précisés de longueur (a) entre des segments longitudinaux spécifiés s'étendant de l'axe de symétrie du canal de déversement au périmètre sur la surface supérieure et la surface inférieure de la plaque respectivement, et (b) entre des segments latitudinaux spécifiés s'étendant de l'axe de symétrie du canal de déversement au périmètre sur la surface supérieure et la surface inférieure de la plaque respectivement, améliorent l'uniformité de la force de poussée appliquée sur les plaques et la zone de contact entre les surfaces supérieures de deux plaques dans un robinet.
Patent CA-3010730-C (CA)
Inventor: HAKOZAKI TOMOHIRO
IPC: A61K8/60
Filed: 2017-01-10
Granted: 2021-02-16
Abstract: La présente invention concerne des méthodes et des compositions cosmétiques permettant d'améliorer l'aspect et la fonction barrière de la peau. Lesdites méthodes et compositions utilisent une association de niacinamide et d'un saccharide approprié à un pH faible pour diminuer la perte d'eau transépidermique par la peau, réduire la taille des tâches dues à une hyperpigmentation, et améliorer l'aspect de la peau par rapport à leurs contreparties à pH élevé.
Patent CA-3015058-C (CA)
Inventor: KAGEYAMA KAZUHIRO
IPC: H01M8/10
Filed: 2016-10-17
Granted: 2019-02-26
Abstract: A fuel cell stack FS includes: a stack A that includes a single cells C that are stacked, each of the single cells including a frame 2 that holds an outer periphery of a membrane electrode assembly 1 and a pair of separators 3, 4 sandwiching the membrane electrode assembly 1 and the frame 2; and a case 50 that houses the stack A. The frame 2 comprises a protrusion 11 that protrudes outward from an outer periphery of a frame body 2A beyond an outer peripheral edge of the pair of separators 3, 4. A protrusion length of the protrusion 11 is greater than at least a gap between the frame 2 and one of the pair of separators 3, 4, and the protrusion 11 is bendable with respect to the frame body 2A. The protrusions prevent a contact between the separators 3, 4 of the single cell C and a contact between the end faces of the separators 3, 4 and the case 50 so as to prevent a short circuit of the single cell C.
Patent CA-3016206-C (CA)
Title: Long-lasting sweetener formulations
Inventor: MO XIAOQUN
IPC: A23L27/10
Filed: 2017-02-28
Granted: 2021-11-23
Abstract: Long-lasting sweetener formulations which comprise at least one encapsulated sweetener compound and are suitable for use in confectionery products are disclosed. In certain, non-limiting embodiments of the disclosed formulations, the sweetener compound is stevioside, rebaudioside A, rebaudioside B, rebaudioside C, rebaudioside D, rebaudioside E, rebaudioside F, rebaudioside M, steviobioside, rubusoside and dulcoside A. In certain embodiments, the disclosed formulations provide enhanced sweetness duration for chewing gum.
Patent CA-3018191-C (CA)
Inventor: RAE CAROL A
IPC: A61M1/34
Filed: 2017-03-31
Granted: 2022-01-25
Abstract: A three-component composition for use in the treatment of preeclampsia and related disorders wherein a first component comprises a bimodal synthetic carbon particle mixture; a second component comprises a resin bead with at least one affinity ligand directed toward syncytiotrophoblast-derived factor sEndoglin and a third component comprises a resin bead with at least one affinity ligand directed toward syncytiotrophoblast-derived factor soluble Fms-like tyrosine kinase-1.
Patent CA-3035008-C (CA)
Title: A wire rope barrier
Inventor: ALLINGTON CHRISTOPHER JAMES
IPC: E01F15/06
Filed: 2016-07-26
Granted: 2023-10-10
Abstract: A wire rope barrier that uses a cable hanger or hangers that act to retain a cable against a post yet release the cable from the post in a tuneable and controllable manner when the barrier is subjected to an impact force and displacement such as from a vehicle collision. The hanger comprises at least two legs, each with a different axis of rotation relative to the post on which the legs are hooked, the result being that the hanger in an impact releases the post from the cable at a predetermined loading and in a controllable and repeatable manner. In one embodiment described, the hanger legs may extend from a cable holding portion, the legs attaching to opposing sides of the post. In a further embodiment, when a predetermined impact force is imposed on the barrier, at least one hanger releases a retained cable when the at least one leg or a part thereof deforms allowing the cable holding portion to in turn release the cable.
Patent CA-3036354-C (CA)
Inventor: UDY ADAM
IPC: A47L9/04
Filed: 2017-09-08
Granted: 2023-01-03
Abstract: A rotatable agitator is used in a surface clearing head of a surface cleaning apparatus. The agitator is coupled to the cleaning head at least partially within an agitator chamber and is rotated about a pivot axis. The agitator includes an elongated agitator body and a hair migration portion. The hair migration portion includes a continuous row of bristles and a sidewall. The continuous row of bristles and sidewall are at least partially revolved around and extend along at least a portion of the pivot axis from one of a collection area or a first end region of the agitator and either another collection area or a second end region of the agitator. The sidewall extends substantially parallel to the continuous row of bristles within the hair migration portion. The continuous row of bristles and sidewall are configured to reduce hair from becoming entangled in the bristles and to migrate hair towards the collection area or the first end region of the agitator.
Patent CA-3056950-C (CA)
Title: Agronomy calculator tool and method
Inventor: COOLIDGE MICHAEL
IPC: A01C21/00
Filed: 2018-04-10
Granted: 2023-08-01
Abstract: A computer-implemented cloud-based agronomy calculator system and methods. The system comprises a plurality of modular components for receiving and processing data pertaining to agricultural production of commodities by an agricultural producer and for centralizing and storing the received and/or processed data in a single cloud-based database. The producer can provide to one or more third-party suppliers and/or service providers, authorized but restricted access to selected components of their agricultural enterprise management system and cloud-based database so that together, the producer, suppliers and service providers can effectively and cost-efficiently plan and manage the delivery of products and services during a crop production cycle, and the sale of harvested agricultural commodities. Separate modular components may be provided for inputs exemplified by agronomy data, crop production inputs data, and crop growth and performance tracking.
Patent CA-3057029-C (CA)
Title: Low cost radio frequency identification (rfid) dispensing systems
Inventor: REYNOLDS AARON
IPC: B67D7/34
Filed: 2009-12-28
Granted: 2022-06-28
Abstract: A method for establishing and controlling operational parameters of a dispenser employing cal _________________________________ tiidges containing material to be dispensed comprises: installing a first cailiidge for a first time in the dispenser; enabling a learn mode at a dispenser controller; reading data from a first tag on the first cartridge; determining one or more operational parameters from the first tag; storing the one or more operational parameters from the first tag; installing a second cartridge in the dispenser; reading data from a second tag on the second cal idge; enabling the dispenser to be operable with the second cal tiidge if an identified operational parameter in the read data of the second cal tiidge matches one or more of the one or more operational parameters stored in the dispenser; and controlling operation of the dispenser in accordance with the one or more operational parameters stored in the dispenser.