baber/WOPTO huggingface dataset:
Patent NZ-533435-A (NZ)
Title: Injectable depot compositions and uses thereof
Inventor: CHEN GUOHUA
IPC: A61P37/00
Filed: 2002-11-14
Abstract: Injectable depot compositions are provided that include a bioerodible, biocompatible polymer; an aromatic alcohol having miscibility in water of less than or equal to 7 wt. % at 25 DEG C, in an amount effective to plasticize the polymer and form a gel therewith; and a beneficial agent dissolved or homogenously dispersed in the gel, wherein the composition is free of monohydric lower alkanols. The compositions may be readily implanted beneath a patient's body surface by injection, as the aromatic alcohol not only facilitates solubilisation of the polymer, but also acts as a thixotropic agent, substantially increasing the shear thinning behaviour of the composition.
Patent NZ-534076-A (NZ)
Inventor: STONES KEVIN
IPC: B27B17/00
Filed: 2004-07-13
Abstract: A vegetation pruning device 2 comprises a pair of arms 4, 6 adapted to pivot relative to each other about an axis to adjust the angle between them, and having a pair of handle portions 14, 16 adapted to be gripped by a user. The device also includes a motor having a rotary output drive and an endless flexible cutting element 8 mounted to a first arm, which is driven by the rotary output drive. The arms are adapted to be gripped by a user at a pair of the handle portions and a pair of guard members restricts access to the cutting element, with guards and cutting element are substantially coplanar.
Patent NZ-535100-A (NZ)
Title: RAAV vector compositions and methods for the treatment of choroidal neovascularization
Inventor: HAUSWIRTH WILLIAM W
IPC: A61P27/02
Filed: 2003-03-20
Abstract: Methods for the use of recombinant adeno-associated viral (rAAV) vector compositions comprising polynucleotide sequences that express one or more mammalian PEDF or anti-angiogenesis polypeptides are disclosed. The methods can be used for the treatment or prevention of symptoms of ocular disorders including blindness, loss of vision, retinal degeneration, macular degeneration, and related disorders resulting from retinal or choroidal neovascularization. The adeno-associated viral vectors comprise a polynucleotide that comprises a nucleic acid segment that encodes a choroidal or ocular neovascularization inhibitory polypeptide selected from the group consisting of pigment epithelium-derived factor (PEDF), endostatin, neuropilin-1, interferon-alpha (INF-a), kinase insert domain receptor (KDR), tyrosyl-tRNA synthetase, tryptophanyl-tRNA synthetase, thrombospondin, plasminogen, tissue inhibitor of metalloproteinase-3 (TIMP3), VEGF Exon 6 peptide, and VEGF Exon 7 peptide, operably linked to a beta-actin promoter that expresses said segment to produce said polypeptide in a selected mammalian host cell.
Patent NZ-541471-A (NZ)
Title: System for predicting speech recognition accuracy and development for a dialog system
Inventor: STARKIE BRADFORD
IPC: G06F40/00
Filed: 2004-02-11
Abstract: A system for developing a dialog system includes a grammatical inference engine for generating grammars for the dialog system on the basis of respective sets of example input phrases for the dialog system; a learning curve estimator for determining, on the basis of the grammars, a relationship between a number of example input phrases and an estimated probability that an input phrase is correctly recognised; and an estimator for generating an estimate of the number of example input phrases required to achieve a predetermined speech recognition accuracy when using the dialog system to allow a developer of the dialog system to determine development of the dialog system. The sets include different numbers of example input phrases.
Patent NZ-544800-A (NZ)
Title: Apparatus, method, and system for applying substances to pre-harvested or harvested forage, grain, and crops
Inventor: OEPPING JAMES M
IPC: B05B7/26
Filed: 2004-07-27
Abstract: An apparatus, method and system for applying a biologically active or chemical substance to a relatively large volume harvested or pre-harvested crop includes relatively small container of a mixture biologically active or chemical substance and water in fluid communication with fluid conduit. A pump moves mixture from the bottle through the conduit. A source of pressurized air is in fluid communication with the conduit to aerate the mixture. The aerated mixture is expelled through a nozzle at distal end of the conduit. In one aspect, the controller can monitor speed of the pump by monitoring operating voltage of the pump. Speed of the pump can be adjusted to adjust application rate. In one aspect, a process combines a flow of air through an orifice with the metering of a low volume of additive, such as an aid to preservation, to a crop as it is being cut or harvested to provide for even distribution of the additive to the crop.
Patent NZ-545513-A (NZ)
Title: Interactive inflatables
Inventor: NEWTON JOHN
IPC: A63G21/00
Filed: 2006-02-24
Abstract: The Interactive Inflatable allows the movement of a platform which is connected to a larger inflatable structure by intermittently forcing air by the use of a timer controlled fan into a chamber to allow at least one human child to be moved to a second position and when the fan turns off the air disperses and the human is returned back to the original position.
Patent NZ-546539-A (NZ)
Title: Separation apparatus and method
Inventor: RICE MATTHEW
IPC: B01D17/02
Filed: 2004-11-04
Abstract: Method of monitoring a papermaking process comprising; withdrawing a liquid fluid mixture from a pulp suspension comprising fibrous and filler materials and colloidal substances; pressurising and supplying the liquid fluid mixture to a separation apparatus, the separation apparatus comprising at least two rotatable discs 6 defining at least one space 6a between the discs, means for withdrawing a dense fraction of the liquid fluid mixture from the perimeter of the discs 6,the discs being arranged to a rotatable axis 7 defining within it at least one bore 8 fluidly communicating with the at least one space 6a, the at least one bore 8 having at least one outlet 10 for removing a light fraction of the liquid fluid mixture, subjecting the supplied pressurised liquid fluid mixture to centrifugal forces at the at least one space 6a by rotating the at least two rotatable disc 6 such that a light fraction of the liquid fluid mixture comprising colloidal substances is pressed to the at least one bore 8 for withdrawal thereof, and a dense fraction of the liquid fluid mixture comprising fibrous and filler materials is pressed to the perimeter of the discs 6 for withdrawal thereof; guiding the withdrawn light fraction to an analyser for characterisation thereof or at least one component therein to monitor a papermaking process.
Patent NZ-550897-A (NZ)
Title: Synergistic combinations comprising a renin inhibitor for cardiovascular diseases, aliskiren and a diuretic
Inventor: HEWITT WILLIAM
IPC: A61K31/506
Filed: 2001-11-15
Abstract: Disclosed is a pharmaceutical composition comprising the rennin inhibitor of formula (I) or a pharmaceutically acceptable salt thereof and a diuretic or a pharmaceutically acceptable salt thereof; and a carrier. Also disclosed is the use of a combination of the rennin inhibitor of formula (I) or a pharmaceutically acceptable salt thereof in combination with a diuretic or a pharmaceutically acceptable salt thereof, for the manufacture of a medicament for the prevention of, delay of progression of, or treatment of chronic renal failure, isolated systolic hypertension (ISH), diabetic retinopathy, and peripheral vascular disease and other diseases or conditions as described in the specification.
Patent NZ-552959-A (NZ)
Title: Compositions and methods for increasing bone mineralization
Inventor: BRUNKOW MARY W
IPC: C12Q1/6883
Filed: 1999-11-24
Abstract: Disclosed is an isolated nucleic acid molecule selected from the group consisting of: (a) an isolated nucleic acid molecule consisting of nucleotides 119-686 of SEQ ID NO: 1 or the complement thereof; (b) an isolated nucleic acid molecule consisting of a nucleotide sequence that encodes amino acids 25-213 of SEQ ID NO: 2; and (c) an isolated nucleic acid molecule that is capable of hybridizing to nucleotides 119-686 of SEQ ID NO: 1 or the complement thereof under conditions of high stringency, wherein said nucleic acid molecule encodes a polypeptide that retains the ability to decrease bone mineral content, and wherein said nucleic acid molecule excludes SEQ ID NOs: 1, 5, 7, 9, 11, 13, 15, sequences at least 95% identical thereto, and the complements thereof. Also disclosed are vectors and host cells containing the nucleic acid molecule, and antibodies able to increase bone mineral content.
Patent NZ-555644-A (NZ)
Title: Potent LNA oligonucleotides for the inhibition of HIF-1A expression
Inventor: RASMUSSEN FRANK WINTHER
IPC: C12N15/113
Filed: 2005-11-09
Abstract: Disclosed is an LNA oligonucleotide consisting of the sequence: 5'- TsGsGscsasasgscsastscscsTsGsTsa -3', Wherein a capital letter designates a beta-D-oxy-LNA nucleotide analogue, a small letter designates a 2-deoxynucleotide, and subscript "s" designates a phosphorothioate link between neighbouring nucleotides/LNA nucleotide analogues. The LNA oligonucleotides are useful for modulating the expression of hypoxia-inducible factor-la (HIF-1a). Further disclosed is the use of the oligonucleotide in the manufacture of a medicament for treating cancer, inhibiting angiogenesis, inducing apoptosis, preventing cellular proliferation, and treating an angiogenic diseases such as diabetic retinopathy, macular degeneration (ARMD), psoriasis, and rheumatoid arthritis.
Patent NZ-555952-A (NZ)
Title: Highly efficient complex of apparatus for spirit production and further purification
Inventor: NIKOLAEV DMITRIY
IPC: C12G3/00
Filed: 2007-06-19
Abstract: An continuous distillation apparatus for spirit production, comprises a continuous distillation column with a dephlegmator 1 attached to its top, an instant action tubular steam generator 3 connected to a steam distributing "T" shaped drilled tube 2 installed in the middle of the column, a water tank 4 with a ball-cock supply valve to supply water to the steam generator 3, a waste/ferment heat exchanger 5 located at the bottom of the continuous distillation column that preheats an ethanol containing mash, a waste/water heat exchanger 6 attached to the bottom of the waste/ferment heat exchanger 5 that preheats water supplied to the steam generator 3, a spirit/ferment heat exchanger 7 connected to the dephlegmator 1, a low pressure ferment supply centrifugal pump 8 that supplies ferment to the continuous distillation column through the spirit/ferment heat exchanger 7, and a ferment flow control valve 9. The heat exchangers help recover heat that would otherwise be lost with the distillation waste products.
Patent NZ-563336-A (NZ)
Title: System and method for unlimited licensing to a fixed number of devices
Inventor: ACHE MARC
IPC: H03M1/68
Filed: 2006-05-16
Abstract: A method and a system for allowing access to electronic content are disclosed. The system comprises a user device configured to render the electronic content; a unique ID permanently stored on the user device and uniquely identifying the user device; a licensing server in communication with the user device and resolving requests for the electronic content; and an authorization database storing a list of authorized unique IDs. The licensing server is configured to access the authorization database to determine whether the user device is an authorized user device and permit the fulfilment of the request for electronic content only to the authorized user device.
Patent NZ-572372-A (NZ)
Title: Plant cultivation method using channels of plastic sheets in layers
Inventor: BELMONTE NAVARRO LORENZO
IPC: A01G31/02
Filed: 2007-03-30
Abstract: To cultivate plants 9 the plant roots 15 are placed through the upper cover 5 of an arrangement of several superimposed channels of V-folded plastic sheets 1, 3, 4 which are supported at the free edges 6, 7 by a pair of rods or cables 2 so as to have spaces 13, 17, 18 between the sheets, and an aqueous solution containing plant nutrients is circulated in a cascade fashion through the spaces. The first space between an upper sheet and the cover incorporates a mass 14 of a substrate in which the plants are rooted and which is kept permanently moist with the nutrient solution. This combination of hydroponic and media growing environment permits a steady supply of micronutrients to be supplied to the plants.
Patent NZ-577442-A (NZ)
Title: Arylsulfonamide compounds
Inventor: BAELL JONATHAN BAYLDON
IPC: A61K31/517
Filed: 2007-11-15
Abstract: Disclosed are pyrimidine-arylsulfonamide compounds represented by general formula (I), or pharmaceutically acceptable salts thereof. An example of a compound of formula (I) is N-{ 7-[4-(4'-Chloro-biphenyl-2-ylmethyl)-piperazin-1-yl]-quinazolin-4-yl} -4-((R)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-nitro-benzenesulfonamide. Also disclosed is the use of the compounds for regulating the death of a cell, inducing apoptosis in unwanted or damaged cells or treating a pro survival Bcl-2 member mediated disease.
Patent NZ-579713-A (NZ)
Title: Device for reducing the size of paper particles including beaters and a sieve type screen
Inventor: WEBB DONALD BARRY
IPC: B02C13/18
Filed: 2008-04-22
Abstract: Disclosed is a device for reducing the size of paper particles. A housing (12) contains an inlet (15) for receiving material into a flow chamber (22). At least two adjacently spaced particle reduction stages (30, 40, 50) exist, through which material flows from one stage to the other for reducing the particle size of the material. An outlet (16) outputs processed material with reduced particle size. Each particle reduction stage has an impact member that rotates about a central shaft (20) for impacting material into smaller particles. At least one of the stages has a screen (45) located downstream from the impact member of that stage, the screen having perforations through which particles of a sufficiently small size can pass. The impact member of at least this stage has elongated beaters (32, 42, 52) supported on and extending radially from a beater plate (33, 43, 53) mounted to the central shaft.
Patent NZ-580161-A (NZ)
Title: Container with a temperature logger having a radio frequency antenna outside and battery in an insulated wall
Inventor: WINDISCH TOM
IPC: F25D29/00
Filed: 2008-04-29
Abstract: Disclosed is an insulated container having an embedded temperature sensor for transporting a temperature sensitive article to allow monitoring of the internal space temperature. The container comprises multiple walls and a removable lid defining a transportable container having an outer surface, an inner surface, and an interior space. The walls comprise a thermal insulation material such that an article in the interior space of the container can be maintained at a desired temperature during transport, and the inner surface of the container faces the interior space of the container. Also included is a radio frequency transponder having a radio frequency circuit and a radio frequency antenna and a temperature sensor monitoring the interior space temperature of the container. An electrical circuit extends through one of the walls connecting the temperature sensor with the radio frequency antenna so that a temperature measurement of the interior space is received by the transponder. A battery that is located in one of the walls of the container powering the temperature measuring equipment. The battery is located within the wall so that the battery remains in an operating temperature range of the battery. The battery and the radio frequency antenna are in a housing located in the lid while the electrically connected temperature sensor is located outside the housing.
Patent NZ-580178-A (NZ)
Title: Bactericidal anti-mrsa active pharmaceutical composition containing carbapenems
Inventor: PFAENDLER HANS RUDOLF
IPC: A61K31/43
Filed: 2008-05-14
Abstract: Disclosed is an anti-MRSA active and bactericidal pharmaceutical composition containing a carbapenem antibiotic and epicillin, their salts, prodrug ester or prodrug amide derivatives. Preferentially the carbapenem antibiotic is a sulphur containing compound of formula (I) where the variables are as described in the disclosure. Also disclosed is the use of the compound for the manufacture of a medicament for treating MRSA (Methicillin-resistant Staphylococcus aureus) or MRSE (Methicillin-resistant Staphylococcus epidermidis) infection and the process for making the pharmaceutical composition.
Patent NZ-580736-A (NZ)
Title: Ribbon cutter apparatus and method for making sandwich baked goods
Inventor: ROBINSON CHRIS E
IPC: B29C48/305
Filed: 2009-10-28
Abstract: As a bottom base cake 12 having a leading edge 14 and a trailing edge 16 is conveyed past a die aperture 82 the position of the base cake is detected by detector 20 and a ribbon 30 of filler extruded through the die aperture is deposited onto the bottom base cake so that the leading edge of the ribbon is at or near the leading edge of the bottom base cake. The ribbon is then severed by a blade 25 to form a laminate of filler on the bottom base cake, the severance of the ribbon and motion or the blade blocking the die aperture and preventing further flow of filler through the die aperture until the next bottom base cake is detected and the die aperture is opened to allow filler to be deposited on the next cake. Top cakes 38 can be placed on the filled bottom base cakes to make sandwiched baked goods 5.
Patent NZ-583763-A (NZ)
Title: A water heating system with a main water heater, an auxillary storage heater and a thermal switching valve
Inventor: BOURKE BRENDAN VINCENT
IPC: F24H9/20
Filed: 2010-03-08
Abstract: A water heating system with a temperature controlled bypass valve is disclosed. The system includes a first water heater 1.030 and a second water heater 1.002. A thermally actuated 3-way valve 1.070 having three ports: an input port 1.075 and two output ports 1.071, 1.073. The input port 1.075 is connected to the output 1.036 of the first water heater 1.030. The first output 1.071 of the valve 1.070 is connected to the input 1.021 of the second heater 1.002. The second output valve 1.073 is connected to the system output 1.050. The output 1.014 of the second heater 1.002 is also connected to the system output 1.050. The valve 1.070 is controlled by temperature. In operation, the second heater 1.002 maintains water in its container within a predetermined storage temperature range. When the flow sensor detects the flow of water it turns the first water heater 1.030 on. Because the initial water flow from the first water heater 1.030 is below the threshold, the thermally activated valve 1.070 initially directs the water from the first heater outlet 1.036 to the inlet 1.021 of the second heater 1.002. This displaces the water in the second water heater through its outlet 1.014 to the system outlet 1.050. Thus the water in the second heater is delivered to the system outlet 1.050, while the cooled water from the first heater 1.030 is stored in the second water heater. When the first heater 1.030 has heated its outlet water to the predetermine threshold temperature, the thermally activated valve 1.070 switches the flow to its second output port 1.073 and thence to the system outlet 1.050, and closes off the flow via its first outlet port 1.071. Thus the flow through the second water heater 1.002 is stopped.
Patent NZ-584373-A (NZ)
Title: Method of producing 2' -deoxy-5-azacytidine (decitabine)
Inventor: JUNGMANN OLIVER
IPC: C07H19/12
Filed: 2008-10-10
Abstract: Method of producing 2'-deoxy-5-azacytidine (Decitabine, which is a nucleoside and a known pharmaceutically active compound) by providing a compound of formula (I), wherein R is a removable substituent known per se (preferably, R is selected from phenylcarbonyl, tolylcarbonyl and xylylcarbonyl); and R1 is a removable substituent (preferably, R1 is selected from chlorine, bromine, fluorine, chlorine, trichloromethyl imidate and -S-methyl); further providing a silylated base of formula (II), wherein R2 is a protecting group (preferably, R2 is a trimethylsilyl (TMS)-residue); reacting the compound of formula (I) and the compound of formula (II) together in a suitable anhydrous solvent and in the presence of a suitable catalyst (preferably, the catalyst is a lithium, sodium, potassium, or magnesium salt of methylsulphonic acid and/or a salt of trifluoromethanesulfonic acid); and removing the substituents R from the compound obtained in order to obtain the compound 2'-deoxy-5-azacytidine (Decitabine), characterized in that said catalyst is selected from the group comprising a salt of an aliphatic sulphonic acid or a salt of a strong inorganic acid.
Patent NZ-588547-A (NZ)
Title: N-(4-Chloro-3-(pyridin-2-yl)phenyl)-4-(2-hydroxy-2-methylpropylsulfonyl)-2-methylbenzamide
Inventor: GUNZNER JANET L
IPC: C07D403/06
Filed: 2009-04-10
Abstract: Disclosed is the compound N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(2-hydroxy-2-methylpropylsulfonyl)-2-methylbenzamide. Further disclosed a composition which comprises the above compound, and a pharmaceutically acceptable carrier for the treatment of cancer in a mammal.
Patent NZ-589820-A (NZ)
Title: Anti-il6 antibodies, compositions, methods and uses
Inventor: CHEN YAN
IPC: A61K39/395
Filed: 2006-04-28
Abstract: Provided is an isolated nucleic acid molecule encoding an IL-6 antibody, comprising a specified nucleotide sequence or corresponding specified nucleotide motifs for the light and heavy chain three CDRs. Further provided are corresponding expression vectors, host cells with the vectors and methods of producing the antibody.
Patent NZ-591212-A (NZ)
Title: pillow block for a segmented media-lubricated plain bearing having a sliding lining of variable thickness
Inventor: HOLSTEIN BENJAMIN
IPC: F16C17/03
Filed: 2009-12-14
Abstract: 591212 Disclosed is a pillow block (1) for a segmented media-lubricated plain bearing with a base body (2) comprising a contact surface (10). A sliding lining is disposed on the contact surface and forms a sliding surface (13), comprising a polymer material and associated with a centre of the surface (12). The material thickness of the sliding lining (3) in the direction of the surface normal to the sliding surfaces in the unloaded state at the edge of the sliding surface is greater than at the centre of area. The local differences in material thickness of the sliding lining are formed by the surface profile of the contact surface of the base body, and the contact surface of the base body comprises a convex profile or a raised area in the form of a level base in the region of the centre of area.
Patent NZ-594248-A (NZ)
Title: Conjugate based systems for controlled drug delivery
Inventor: ZION TODD C
IPC: C07K14/62
Filed: 2010-01-27
Abstract: Disclosed is a conjugate comprising an insulin molecule conjugated to one or more ligands wherein at least one ligand is aminoethyltrimannose (AETM), and preferably wherein the insulin molecule is conjugated via the A1 amino acid residue, via the B1 amino acid residue, or via the epsilon-amino group of LysB29. Also disclosed is a sustained release formulation comprising an insulin conjugate as defined above, and which may further comprise protamine and zinc, for use in treating hyperglycemia or diabetes.
Patent NZ-594395-A (NZ)
Title: Use of eicosapentaenoic acid ethyl ester for treating hypertriglyceridemia
Inventor: WICKER PIERRE
IPC: G16Z99/00
Filed: 2010-02-09
Abstract: 594395 Disclosed is the use of ethyl eicosapentaenoate in the manufacture of a pharmaceutical composition for reducing triglycerides and apolipoprotein B levels without substantially increasing LDL-C in a subject having a fasting baseline triglyceride level of 500 mg/dl to about 1500 mg/dl wherein about 4 g per day of the pharmaceutical composition is to be administered orally to the subject and wherein at least about 80%, by weight of all fatty acids present in the composition comprise ethyl eicosapentaenoate.