baber/WOPTO huggingface dataset:
Patent CA-2499467-A1 (CA)
Inventor: JOHNSEN ANDERS H
IPC: C12N1/19
Filed: 2003-09-19
Abstract: The present invention provides a host cell comprising a nucleic acid sequence encoding a recombinant polypeptide in which the production of a naturally occurring metalloprotease comprising the sequenc HXXEH has been reduced or inhibited by genetic manipulation. The present invention also relates to methods for enhancing the production of a polypeptide from a cell by disrupting the synthesis or activity of the metalloprotease. In particular, the present invention relates to methods for enhancing the secretion of recombinant polypeptides from host cells such as, but not limited to, yeast and bacterial cells. The metalloprotease is a member of the pitrilysin subfamily of proteases, characterized by comprising the sequence HXXEH, where X is any amino acid.
Patent CA-2503475-A1 (CA)
Inventor: WILLIAMS P MICKEY
IPC: C12N1/15
Filed: 1999-11-30
Abstract: Compositions and methods are disclosed for stimulating or inhibiting angiogenosis and/or cardiovascularization in mammals, including humans. pharmaceutical compositions are based on polypeptides or antagonists thereto that have been identified for one or more of these uses. Disorders that can be diagnosed, prevented, or treated by the compositions herein include trauma such wounds, various cancers, and disorders of the vessels including atherosclerosis and cardiac bypartrophy. In addition, the present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present inventions fused to heterologous polypeptides sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Patent CA-2504312-A1 (CA)
Title: System and method for providing media samples on-line in response to media related searches on the internet
Inventor: COOK DAVID
IPC: G06Q30/02
Filed: 2003-10-30
Abstract: A method and system are described for providing a streamlined method for usi ng (figure 2A), for example, streaming media samples to promote and sell music, videos and related merchandise on the Internet in response to searches for entertainment related information (figure 2A, 200/210). When a consumer ente rs an Internet search query that includes a Media Keyword (figure 2A, 200) a corresponding media sample or sample set is identified for the consumer to select to receive as a stream or download onto the Consumer Device (figure 2 A, 260), along with search results pertaining to the requested information and purchasing options (figure 2A, 220/250). The media sample or sample set is provided as a link in a web page (figure 2A, 270) containing search results generated for the consumer (figure 2A, 295). The media sample link may be indicated on the web page as a preferred, personalized or sponsored search result (figure 2A, 240/290).
Patent CA-2504868-A1 (CA)
Title: Multiple-variable dose regimen for treating tnf.alpha. related disorders
Inventor: YAN PHILIP
IPC: C07K16/24
Filed: 2005-04-11
Abstract: Multiple-variable dose methods for treating TNF.alpha.-related disorders, including Crohn's disease and psoriasis, comprising administering TNF.alpha. inhibitor s, including TNF.alpha. antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administrati on of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase.
Patent CA-2504875-A1 (CA)
Title: Coated multifilament dental devices overcoated with imbedded particulate
Inventor: BROWN DALE G
IPC: A61C15/04
Filed: 2003-10-30
Abstract: Disclosed are coated multifilament dental devices overcoated with biofilm- responsive, imbedded, particulate abrasives.
Patent CA-2507181-A1 (CA)
Title: Mixed oxide catalyst of rb, ce, cr, ni, fe, bi and mo for the manufacture of acrylonitrile
Inventor: JEVNE STEPHEN C
IPC: B01J23/887
Filed: 2003-11-19
Abstract: A catalyst comprising a complex of catalytic oxides comprising rubidium, cerium, chromium, iron, bismuth, molybdenum, and at least one of nickel or nickel and cobalt, optionally magnesium, and optionally one of phosphorus, antimony, tellurium, sodium, lithium, potassium, cesium, thallium, boron, germanium, tungsten calcium, wherein the relative ratios of these elements are represented by the following general formula: Rba Ceb Crc Mgd Ae Fef Big Yh Mo12 Ox wherein A is Ni or the combination of Ni and Co, Y is at least one of P, Sb, Te, Li, Na, K, Cs, TI, B, Ge, W, Ca, Zn, a rare earth element, or mixtures thereof, a is about 0.01 to about 1, b is about 0.01 to about 3, c is about 0.01 to about 2, d is 0 to about 7, e is about 0.01 to about 10, f is about 0.01 to about 4, g is about 0.05 to about 4, h is 0 to about 3, x is a number determined by the valence requirements of the other elements present, wherein "b" + "c" is greater than "g" and wherein the catalyst is substantially free of manganese, a noble metal and vanadium. The catalyst is useful in processes for the ammoxidation of an olefin selected from the group consisting of propylene, isobutylene or mixtures thereof, to acrylonitrile, methacrylonitrile and mixtures thereof, respectively.
Patent CA-2507631-A1 (CA)
Title: Variant d'epissage de l'hormone de croissance hypophysaire humaine
Inventor: FAGAN RICHARD JOSEPH
IPC: C07K14/61
Filed: 2003-12-05
Abstract: Cette invention concerne une nouvelle protéine, dite INSP101, identifiée comme nouveau variant d'épissage de l'hormone de croissance hypophisaire humaine, et l'utilisation de cette protéine et de la séquence d'acide nucléique tirées des gènes codants pour le diagnostic, la prévention et le traitement de maladies.
Patent CA-2508073-A1 (CA)
Inventor: LEDIEU MARC
IPC: H01Q7/06
Filed: 2004-08-30
Abstract: A high-impedance substrate including a first layer made of insulating material, having a lower face and an upper face, the substrate including conductor patterns mechanically linked to the substrate. Some of the conductor patterns mechanically linked to the substrate are associated with a magnetic tile. At least one electrical interconnection puts two points distinct from one another of a conductor pattern mechanically linked to the substrate in electrical contact, this conductor pattern having an assigned magnetic tile, passing above the magnetic tile associated with the conductor pattern mechanically linked to the substrate.
Patent CA-2508301-A1 (CA)
Inventor: BOSCH WILLIAM H
IPC: A61K9/00
Filed: 2003-04-23
Abstract: L'invention concerne des formes posologiques liquides d'agents actifs nanoparticulaires présentant de très faibles viscosités.
Patent CA-2508804-A1 (CA)
Title: Apparatus and method for a scalable network attach storage system
Inventor: CAFIERO LUCA
IPC: H04L69/40
Filed: 2003-11-19
Abstract: An apparatus and method for a scalable network attached storage system. The apparatus includes a scalable network attached storage system, the network attached storage system including one or more termination nodes, one or more file server nodes for maintaining file systems, one or more disk controller nodes for accessing storage disks respectively, and a switching fabric coupling the one or more termination node, file server nodes, and disk controller nodes. The one or more termination nodes, file server nodes and disk controller nodes can be scaled as needed to meet user demands. The method includes receiving a connection request from a client, selecting a termination node among the plurality of termination nodes to establish a connection with the client in response to the connection request based on a predetermined metric, terminating at the selected termination node a command request received from the client during the connection by extracting a file handle defined by the command request, forwarding the command request to a selected file server node among a plurality of file server nodes interpreting the command request at the selected file server node and accessing an appropriate disk controller node among a plurality of disk controller nodes, and accessing disk storage through the appropriate disk controller node and serving the accessed data to the client. The number of termination nodes, file server nodes, and disk controller nodes are scalable as needed to meet user demands.
Patent CA-2511085-A1 (CA)
Title: Lo-cd2a antibody and uses thereof for inhibiting t-cell activation and proliferation
Inventor: BAZIN HERVE
IPC: A61K39/395
Filed: 1994-03-04
Abstract: The present invention relates to a LO-CD2a antibody and methods of using such antibodies or molecules that bind to the same epitope (or a portion thereof) to prevent and inhibit an immune response in human patients, preferably, where the immune response is mediated by the activation and proliferation of T cells or natural killer cells. The administration of an effective amount of the LO-CD2a antibody to a human patient will prevent or inhibit graft rejection, graft versus host disease or autoimmune disease.
Patent CA-2514133-A1 (CA)
Title: Reverse printing
Inventor: ONG BENG S
IPC: H01L51/40
Filed: 2005-07-29
Abstract: A method of patterning organic semiconductor layers of electronic devices utilizing reverse printing.
Patent CA-2515971-A1 (CA)
Title: Nitrate esters of phenylaminothiophenacetic acid derivatives
Inventor: GRUNDLER GERHARD
IPC: A61P29/00
Filed: 2004-02-17
Abstract: The compounds of formula I in which R1, R2, R3, R4 and R5 have the meanings as given in the description are novel effective antiinflammatory compounds.
Patent CA-2522412-A1 (CA)
Title: Wearing article
Inventor: WATANABE MAKI
IPC: A41D27/00
Filed: 2004-05-21
Abstract: The present invention aims to provide a wearing article so improved to eliminate a possibility that desired stretchability and flexibility of the wearing article might be deteriorated due to the presence of the hook member making one component of the mechanical fastener attached to the wearing article.     A wearing article such as a disposable diaper is provided in predetermined regions of the article with hook members (16) .  These predetermined regions are elastically stretchable at least in one direction. Each of the hook members (16) comprises a plurality of hook assemblies (21) which are, in turn, attached to each of the predetermined regions so as to be spaced apart one from another in the one direction.
Patent CA-2523611-A1 (CA)
Inventor: ZHANG WENLIN
IPC: H04L12/28
Filed: 2004-12-01
Abstract: The present invention discloses an access gateway of IVLAN, and it comprises:  a constrained route module for constraining to control transmission route and a charging module for collecting charging information. After the data packets transmitted via the access gateway of WLAN are processed by constrained route process and collection of charging information, they are output to the service certification authorization unit, the packet data gateway or the user terminal of WLAN. The gateway further comprises: message filtrating module, which acquires and stores policy data and performs discrimination, filtration and shield to the data packet passing currently. The message filtrating module is connected to the constrained route module and the charging module. The present invention also discloses a method for ensuring network security using the access gateway of WLAN. The said accesa gateway and method could process data packet with discrimination, filtration and shield, in order to maximally avoid the interfere and threat to network operation from illegal message and the transmission of illegal data packet. It could improve network security and decrease network burden.
Patent CA-2523688-A1 (CA)
Title: Tube multicouche po / adhesif / evoh / pa / couche de protection
Inventor: CHENG CYRIELLE
IPC: F16L11/10
Filed: 2005-10-18
Abstract: Tube multicouche comportant de l'intérieur vers l'extérieur : - une couche interne en polyoléfine, - une première couche intermédiaire à base d'adhé- sif, - une deuxième couche intermédiaire en éthylène vi- nylidène alcool, - une troisième couche intermédiaire en polyamide, - une couche externe de protection.
Patent CA-2523821-A1 (CA)
Title: Method and apparatus for control of carbon dioxide gas cooler pressure by use of a two-stage compressor
Inventor: MANOLE DAN M
IPC: F25B31/00
Filed: 2005-10-20
Abstract: A transcritical vapor compression system includes a fluid circuit circulating a refrigerant in a closed loop. The fluid circuit has operably disposed therein, in serial order, a first compressor, an intercooler, a second compressor with a variable capacity, a first heat exchanger, an expansion device and a second heat exchanger. The first compressor compresses the refrigerant from a low pressure to an intermediate pressure.  The second compressor compresses the refrigerant from the intermediate pressure to a supercritical pressure. The first heat exchanger is positioned in a high pressure side of the fluid circuit. The second heat exchanger is positioned in a low pressure side of the fluid circuit. The expansion device reduces the pressure of the refrigerant from a supercritical pressure to a relatively lower pressure. Cooling means cools the refrigerant within one of the compressors.
Patent CA-2524949-A1 (CA)
Title: Systemes homogenes de saccharide liquide et d'huile
Inventor: LINDNER GREG J
IPC: A01N57/26
Filed: 2004-05-07
Abstract: Cette invention concerne des concentrés émulsifiables d'huile contenant un saccharide liquide et comprenant a) au moins un composant huile, b) au moins un saccharide, en particulier une solution saccharidique liquide (LS), et c) au moins un tensioactif non ionique. Ce concentré peut également renfermer au moins (d) un saccharide d'hydrocarbyle tensioactif ou ; (e) au moins un tension actif anionique ; ou (f) au moins un tensioactif non ionique supplémentaire soluble dans l'huile. Généralement parlant, ces concentrés restent homogènes pendant au moins 24 heures et se transforment facilement en émulsion par dilution dans l'eau. Les concentrés peuvent également contenir un agent anti-moussant, en particulier un polysiloxane. Ces concentrés sous forme d'émulsions obtenus par dilution dans l'eau sont appliqués sur des substrats en combinaison avec des principes actifs au plan agrochimique, de préférence avec des sels solubles de N-phosphonométhylglycine, et s'utilisent pour combattre les mauvaises herbes.
Patent CA-2525012-A1 (CA)
Title: Protein kinase c zeta as a drug target for arthritis and other inflammatory diseases
Inventor: COLLINS-RACIE LISA A
IPC: C12Q1/68
Filed: 2004-05-10
Abstract: The present invention is based on the discovery that .zeta.PKC expression is increased in the tissues of arthritis patients as compared to normal individuals. Accordingly, the present invention provides methods of diagnosing, prognosing, and monitoring the course of arthritis in a patient based on increased .zeta.PKC gene expression in arthritic tissue. The present invention further provides compounds that inhibit the expression of .zeta.PKC  for use as remedies in the treatment of arthritis, including, but not limited to, inhibitory polynucleotides and polypeptides, small molecules, and peptide inhibitors. In addition, the present invention provides pharmaceutical formulations and routes of administration for such remedies, as well as methods for assessing their efficacy.
Patent CA-2525022-A1 (CA)
Title: Play set with toy vehicle track and carriage
Inventor: BEDFORD JONATHAN
IPC: A63H18/02
Filed: 2005-11-01
Abstract: In some examples, a toy vehicle play set may include an elongate track having a first vehicle-support surface defining a travel path, and a carriage mounted for travel along the travel path and having a second vehicle-support surface. The first and second vehicle-support surfaces may be configured to support, in combination, a toy vehicle.
Patent CA-2526034-A1 (CA)
Title: Reverse circulation cementing process
Inventor: GRIFFITH JAMES E
IPC: E21B21/10
Filed: 2004-05-13
Abstract: A method of cementing a casing in a wellbore with a tool having a plurality of holes (21) therethrough connected at a lower end of the casing. A plurality of stoppers (30) are pumped in a leading edge of a cement slurry (13) down an annulus (14) between the casing and the wellbore to the tool where the stoppers engage the holes to hold the cement slurry in the annulus until the cement slurry hardens. A valve maybe incorporated with the stopper catch tool (20). Stoppers and holes may have various shapes and centrifugal pump (60) may be used.
Patent CA-2527462-A1 (CA)
Title: Electric lamp having an outer bulb
Inventor: VUC MARCEL
IPC: H01J61/34
Filed: 2005-11-22
Abstract: The elongate inner bulb (1) defines a longitudinal axis (A) and is sealed at mutually opposing ends by sealing parts (6; 32), an outer bulb being placed, with an adjoining tube piece, over the inner bulb and being fixed to the sealing part by means of an annular beading formed there, the end of the tube piece being radially attached to the beading, the maximum inner diameter of the beading being larger than the outer diameter of the sealing part in the region of the beading.
Patent CA-2528478-A1 (CA)
Inventor: CUEVAS BRIAN
IPC: A61B17/34
Filed: 2005-11-30
Abstract: A seal assembly for use with an access apparatus during a surgical procedure includes a housing defining a longitudinal axis and having a passageway dimensioned to permit passage of an object. The housing is adapted for mounting to a surgical access apparatus and has internal wall portions defining an internal chamber. A seal is mounted within the internal chamber of the housing and is adapted to form a substantial sealing relation with the object. The seal is mounted for reciprocal movement within the internal chamber in a general transverse direction to the longitudinal axis. A viscous fluid is disposed within the internal chamber surrounding the seal and is adapted to form a substantial seal between the seal and the internal wall portions of the housing. The fluid may have lubricious characteristic to facilitate sliding movement of the seal relative to the internal wall portions of the housing. Alternatively, the fluid includes a therapeutic agent or a pharmacological agent which is released to treat the underlying tissue. A foam material may be disposed within the internal chamber. The foam material is at least partially saturated with the fluid.
Patent CA-2529012-A1 (CA)
Inventor: JICHA THOMAS
IPC: G01S13/935
Filed: 2004-06-09
Abstract: A method of determining a target location from a vehicle (102) is described.  The method includes identifying (12) the target (100) utilizing a video system (124), determining (14) an angular location vector (104) to the target with respect to the vehicle, detennining (16) a position (108) of the vehicle utilizing a digital terrain elevation map (122) and precision radar altimeter (30), calculating a location where the angular location vector would intersect with the digital terrain elevation map, and generating (18) a target position (112) based on vehicle position and the location of the intersection of the angular location vector and digital terrain elevation map.
Patent CA-2529186-A1 (CA)
Title: Electronic security system for monitoring and recording activity and data relating to cargo
Inventor: SAJKOWSKY JAMES M
IPC: G06Q10/08
Filed: 2004-06-17
Abstract: A tracking system for identifying contents of a container includes an electromagnetic identification apparatus that provides an electromagnetic signal indicative of a container content data set; a writer for use in encoding the container signal onto the apparatus; a controller for receiving the encoded signal and for storing the signal in a master database storage apparatus; and a reader configured outside the container for communicating with the electromagnetic identification apparatus and for receiving the encoded signal therefrom and corresponding to the container content data signal set. A system for tracking items in an assembly includes an apparatus for receiving electromagnetic identification tag signals; an apparatus for creating a first tier aggregate signature; an apparatus for storing the signature in a master database; and an apparatus for receiving modifying command signals for creating a second tier aggregate signature corresponding to a modified set of electromagnetic identification tags in an augmented assembly.
Patent CA-2532769-A1 (CA)
Title: Electrical connector
Inventor: ANDREW HUNTER
IPC: H01R13/627
Filed: 2004-07-07
Abstract: The present invention may provide a two-part electrical connector having a first part being a tongue portion (40) having a base (42) and a tongue (46) extending longitudinally therefrom; a second part being a socket portion having a base and walls extending therefrom defining a socket for slidably receiving the tongue (40), the tongue portion and socket portion having locking means (56) to permit releasable mutual engagement, said locking means including a locking member moveable between a first position in which the tongue (40) is held in the socket and a second position in which the tongue is removable from the socket; a primary coupling element (48) located in the tongue (40); and a secondary coupling element located in at least one of the socket walls, which elements provide a contact-less electromagnetic coupling when the tongue is engaged in the socket.
Patent CA-2533592-A1 (CA)
Title: Controlled release compositions
Inventor: COOK GARY P
IPC: A61K38/095
Filed: 2004-07-15
Abstract: The compositions disclosed herein are for use as controlled release therapeutics for the treatment of a wide variety of diseases. In particular, the compositions provide water soluble bioactive agents, organic ions and polymers where the bioactive agent is efficiently released over time with minimal degradation products. The resulting controlled release composition is capable of administration in a decreased dose volume due to the high drug content and predominance of non-degraded bioactive agent after release.  Additionally, the compositions, of the present invention are capable of long term, sustained releases.
Patent CA-2533790-A1 (CA)
Inventor: PATTERSON ALBERT W
IPC: F15B15/24
Filed: 2006-01-24
Abstract: A rotary fluid pressure actuator includes a housing having an inner actuator chamber with a cylindrical side wall extending between a pair of end walls. An integral vane rotor assembly, including a shaft and end discs, is positioned in the chamber and is rotationally reciprocated in response to the direction of flow of fluid to and from chamber segments of the housing. A  fixed dam is secured between flanges in an elongated opening along the cylindrical side wall of the housing, the dam extending radially into the chamber from the opening to abut against the shaft between the end discs. The dam acts as a stop to limit the reciprocal motion of the vane and shaft in each direction
Patent CA-2539003-A1 (CA)
Title: Compositions and methods for topical treatment of skin infection
Inventor: CHIOU WIN L
IPC: A61K33/24
Filed: 2004-11-30
Abstract: The present invention describes an extremely effective, simple, novel, inexpensive, safe and quick method to treat both acne and warts, each with a different etiology and different clinical symptoms, by topically applying an effective and safe amount of one or more polyvalent metal compounds. The present invention can also be used for prophylaxis of acne. The polyvalent metal compounds include, but are not limited to, bismuth compounds, zinc compounds, magnesium compounds, aluminum compounds, calcium compounds, copper compounds, titanium compounds, manganese compounds, chromium compounds, barium compounds, selenium compounds and iron compounds. The present invention can also be applied to the treatment of rosacea. The present invention can also be employed to prevent scarring and to facilitate healing or elimination of the scars once formed, and to be useful in depigmentation. The present invention can also be used for the prophylaxis and treatment of periodontitis and tooth mobility, as well as for promoting healthy growth of oral mucous membranes and tissues.