Patent SG-11201804971V-A (SG)
Title: Systems and methods for conducting electrochemical impedance spectroscopy
Inventor: VAN INGELGEM YVES
IPC: B01L3/00
Filed: 2016-12-18
Abstract: 104 W O 20 17 / 103 244 Al (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2017/103244 Al 22 June 2017 (22.06.2017) WIPO I PCT 11111111111111011101111111111101011111011101011111011101011101111111111111110111111 05 804 103 101 1001 1002 (51) International Patent Classification: GO1N 27/02 (2006.01) G01N 33/483 (2006.01) BOIL 3/00 (2006.01) (21) International Application Number: PCT/EP2016/081627 (22) International Filing Date: 18 December 2016 (18.12.2016) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1522323.3 17 December 2015 (17.12.2015) GB (71) Applicants: VRIJE UNIVERSITEIT BRUSSEL [BE/BE]; Pleinlaan 2, 1050 Brussel (BE). KATH- OLIEKE UNIVERSITEIT LEUVEN [BE/BE]; KU Leuven R&D Waaistraat 6, box 5105, 3000 Leuven (BE). (72) Inventors: VAN INGELGEM, Yves; Dorpstraat 46, 3404 Landen (BE). LANDUYT, Bart; Kronkelweg 50, 3300 Vissenaken (BE). VERGUTS, Sven; Verboeckhavenstraat 62, 1210 Sint-Joost-ten-Node (BE). (74) Agents: WAUTERS, Davy et al.; Denk IP, Leuven- sesteenweg 203, 3190 Boortmeerbeek (BE). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). [Continued on next page] (54) Title: SYSTEMS AND METHODS FOR CONDUCTING ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY (57) : A system for measuring electrical characteristics of bioparticles is described. The system comprises an incubator for performing 110 electrochemical measurements in a defined envir- onment and a substrate holder positioned in said incubator for holding a substrate comprising a plurality of wells (110). The system is further- more configured for continuously or regularly measuring electrochemical data. The system also comprises a processing means for comparing the continuously or regularly measured electrochem- 102 ical data with reference data and for determining a moment for adding an active compound based on said comparison. FIG. 10 WO 2017/103244 Al 1#110H011111 1111NOIDEM30101111101010110IMMOVON Declarations under Rule 4.17: Published: — of inventorship (Rule 4.17(iv)) — with international search report (Art. 21(3))