baber/WOPTO huggingface dataset:
Patent PH-20016-A (PH)
Title: Cardioselective aryloxy-and arylthio-hydroxy-propylene piperazinyl acetamides which affect calcium entry
Inventor: KLUGE ARTHUR F
IPC: A61P9/10
Filed: 1984-05-17
Abstract: Novel compounds of the general formula   <IMAGE> (I)  and the pharmaceutically acceptable esters and acid addition salts thereof, wherein: R1, R2, R3, R4 and R5 are each independently hydrogen, lower alkyl, lower alkoxy, cyano, trifluoromethyl, halo, lower alkylthio, lower alkyl sulfinyl, lower alkyl sulfonyl, N-optionally substituted alkylamido, except that when R1 is methyl, R4 is not methyl; or R2 and R3 together form -OCH2O-; R6, R7, R8, R9 and R10 are each independently hydrogen, lower acyl, aminocarbonylmethyl, cyano, lower alkyl, lower alkoxy, trifluoromethyl, halo, lower alkylthio, lower alkyl sulfinyl, lower alkyl sulfonyl, di-lower alkyl amino; or R6 and R7 together form -CH=CH-CH=CH-; R7 and R8 together form -OCH2O-; R11 and R12 are each independently hydrogen or lower alkyl; and W is oxygen or sulfur. These cardioselective compounds have calcium entry blockade properties and therefore are useful in therapy in the treatment of cardiovascular diseases, including arrhythmias, variant and exercise induced angina and myocardial infarction.
Patent PH-21953-A (PH)
Title: Coated fabric and method of making the same
Inventor: GOMPEL PAUL T VAN
IPC: B32B27/12
Filed: 1986-01-09
Abstract: A coated fabric comprises a base ply of a fiber material such as a non-woven fiber material, for example, a polypropylene non-woven material, having a thermoplastic film, for example, an ethylene methyl acrylate film, bonded thereto. The base ply has densified and undensified portions thereof, the densified portions defining densified areas on a coating surface of the base ply, and the thermoplastic film is heat-bonded to the coating surface at least at the densified portions thereof. A method of making the coated fabric comprises contacting the thermoplastic film in heat-softened condition with the coating surface of the base ply, and allowing the film to cool.
Patent PH-23898-A (PH)
Title: New phenyl pyrrolidin-2-yl substituted-2-yl substituted 5-ring heterocycles having antipsycotic properties
Inventor: WIJNGAARDEN INEKE VAN
IPC: C07D403/04
Filed: 1987-09-08
Abstract: The invention relates to a group of new phenyl, pyrrolidin-2-yl substituted 5-ring heterocyclic compounds of the formula <CHEM> wherein A is an unsaturated heterocylic 5-ring having at least one nitrogen or oxygen atom in the ring, with the proviso that the phenyl substituent is in a meta-position with respect to the 2-pyrrolidinyl substituent. The compounds have interesting pharmacological, notably antipsychotic properties.
Patent PH-25338-A (PH)
Title: Antibacterial substituted bridged-diazabicycloalkyl quinolone carboxyclic acids
Inventor: JEFSON MARTIN RAYMOND
IPC: A61K31/4709
Filed: 1989-07-11
Abstract: Antibacterial compounds have the formula <CHEM> wherein R<1> is hydrogen, a pharmaceutically acceptable cation, or alkyl; A is CH, CF, CCl or N; Y is alkyl, haloalkyl, cyclopropyl, vinyl, methoxy, N-methylamino, p-fluorophenyl, p-hydroxyphenyl or p-aminophenyl; or A is carbon and is taken together with Y and the carbon and nitrogen to which A and Y are attached to form a five to seven membered ring which is optionally substituted; and R<2> is a bridged-diazabicycloalkyl group.
Patent PH-30129-A (PH)
Title: Sertindole prodrug compositions and use
Inventor: PERREGAARD JENS KRISTIAN
IPC: A61P25/20
Filed: 1991-10-01
Abstract: Reaction products of sertindole with an acid or an activated acid, with formaldehyde alone, formaldehyde in the presence of an alcohol or an amine, or with an acyloxymethylene halide, and having general formula (1) wherein X is CO, CS, or CH2, and if X is CO or CS, R is (i) hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl or cycloalk(en)ylalk(en)yl optionally substituted with hydroxy, or optionally substituted phenyl; or (ii) YR1, wherein Y is O or S and R1 is one of the substituents defined for R under (i) above; or (iii) NR2R3, wherein R2 and R3 independently are selected from the substituents defined for R under (i) above or R2 and R3 are combined to form a heterocyclic ring; or if X is CH2, R is: (iv) a group YR1 as defined in (ii); (v) a group NR2R3 as defined in (iii); or (vi) a group OC(O)R4, wherein R4 is as defined for R1; are prodrugs of sertindole and show sustained release of sertindole when injected as formulated in a suitable oil. The compounds are useful in the treatment of mental disorders such as schizophrenia including both negative and positive symptoms, non-schizophrenic psychoses, depression and anxiety.
Patent UY-33431-A (UY)
Title: Sal de tirofibán y uso para reducir la trombacitopenia y mortalidad asociada a la trombocitopenia
Inventor: MARCO VALGIMIGLI
IPC: A61K31/4465
Filed: 2011-06-06
Abstract: Se describen métodos para reducir el riesgo de mortalidad y morbilidad asociadas a trombocitopenia y para reducir el riesgo de trombocitopenia en pacientes cuyo tratamiento requiere inhibición de la agregación plaquetaria.  Los métodos involucran la administración de una sal farmacéuticamente aceptable de tirofiban.
Patent UY-33450-A (UY)
Title: Estructura de hojas multicapa para documentos de identidad
Inventor: VIDAL CELSO EUGENIO MONREAL
IPC: B32B29/00
Filed: 2011-06-10
Abstract: Se proporciona una estructura, en particular, un documento de seguridad tal como un pasaporte. La estructura incluye una primera capa (4) que comprende una zona (40) de opacidad modificada, al menos una capa adicional (30,6,9) fija respecto a la primera capa (4), y un agente luminiscente (37) situado respecto a dicha al menos una capa adicional y la primera capa, de modo que al excitar el algente luminiscente, la luz producida por el agente luminiscente se propaga a través de la primera capa para hacerse observable y hacer visibles las característica de la zona de opacidad modificada. La zona de opacidad modificada no es visible a la luz transmitida desde cualquier lado de la estructura.
Patent UY-34311-A (UY)
Inventor: ABELLA DANIEL FERNANDEZ
IPC: A61K31/137
Filed: 2012-09-04
Abstract: NO SCAN
Patent UY-38033-A (UY)
Title: Combinaciones de lípidos
Inventor: HODGSON CHARLES
IPC: A61K35/56
Filed: 2018-12-21
Abstract: La presente invención se relaciona en general con combinaciones de lípidos marinos. En particular se relaciona con una combinación de lípidos marinos obtenidos de Perna canaliculus y kril, composiciones y preparaciones que comprenden dichas combinaciones y el uso terapéutico de dichas combinaciones y composiciones. También se describen procesos para la elaboración de aceites de kril y su uso en las combinaciones y composiciones.
Patent YU-55290-A (YU)
Title: Sečivo za difuziju svetlosti za primenu u saobraćajnim svetlima i postupak za njegovu izradu
Inventor: GRANSTRAM E
IPC: B29D11/00
Filed: 1990-03-21
Abstract: SEČIVO ZA DIFUZIJU SVETLOSTI ZA PRIMENU U SAOBRAĆAJNIM SVETLIMA I POSTUPAK ZA NJEGOVU IZRADU, pronalazak se odnosi na sočivo za saobraćajno svetlo i na postupak za proizvodnju takvog sočiva za korišćenje u saobraćajnim svetlima itd., i poznate vrste kod kojih se skoro paralelan snop svetlosnih zrakova projektuje na jedno sočivo prilagodjeno da rasipa svetlost unutar izvesnih unapred odredjenih granica, a to sočivo obuhvata veliki broj šupljina rasporedjenih na unutrašnjoj površini sočiva, koje šupljine deluju kao elementarna sočiva rasporedjena u paralelnim redovima (3) koji se pružaju u horizontalnom pravcu, i gde svako od elementarnih sočiva (2) obuhvata najmanje dva integralna konkavna dela sočiva, i to donji deo (5) sočiva koji ima oblik polukugle, i gornji deo (6) sočiva koji je neposredno integralan sa pomenutim donjim delom (5) sočiva, a koji se stepenasto ili postepeno širi do oblika zvona i koji se završava kornjom, pravo odsečenom gornjom površinom (4) sočiva. Sočivo za difuziju svetlosti izradjuje se pravljenjem elektroerozijom gornjeg dela kalupa pomoću dve sadejstvujuće grafitne elektrode sa trakama grafitnog materijala, u kojim su trakama glodanjem načinjene šupljine koje odgovaraju elementarnim sočivima (2) a pomoću sfernog glodača, pri čemu se taj gornji deo kalupa koristi za livenje presovanjem sočiva za difuziju svetlosti.
Patent AT-A191094-A (AT)
Inventor: EDLINGER ALFRED DIPL ING
IPC: C21B11/00
Filed: 1994-10-10
Abstract: Metal oxide-containing waste material is dried and preheated before being fed into a reactor (3) where it is melted and oxidised to produce a slag and a metal bath. The slag is then subjected to a two stage redn. pressure as it flows into an iron bath reactor (4) and then an iron bath calcinator (10). In the reactor, scrap or CO/CO2 is fed in to reduce mainly non-ferrous metals which form a bath which is subjected to segregation melting technique. A raw bronze melt is removed from the bottom of the vessel and recycled to the first reactor. In the second redn. stage, CaCO3, CaO and C and optionally O2 is fed into the vessel to reduce the FeO in the slag ad produce a pig iron melt.
Patent BE-812438-A (BE)
Title: Antiviral-polypeptide complex contg. compsns. - specifically a polyribo-nucleotide and a poly(alpha amino acid) as antiviral agents
IPC: A61K31/785
Filed: 1974-03-18
Abstract: Title medicaments contain a complex of a cpd. known to induce the prodn. of natural antiviral agents in living cells and/or having intrinsic antiviral activity esp. polyribonucleic acid, synthetic polyribonucleotides complexes of two such ribonucleotides or a synthetic copolyribonucleotide, poly I:C, poly A:U, poly (AU) or statalon; and a polycationic polypeptide contg. >=1 units (where A is CO-NH-B-NR1R2 or NR3R4, B is 1-4C-alkylene; R1 and R2 are H or 1-4C alkyl, or NR1R2 is a 5- or 6-membered heterocyclic ring opt. contg. another heteroatom; R3 is 1-4C alkyl and R4 is H or 1-4C alkyl; n is 1-5 or if A is CONH-B NR1R2, n may be 0) or a salt or quaternary ammonium salt thereof, esp. polyglutamic, polyaspartic, poly-(alpha-amino adipic acid), polylysine or polyornithine or amidated or alkylated derivs thereof. The complexes all prepd. by lyophilizing a soln. of the two components.
Patent BE-899286-A (BE)
Title: Intra-uterine contraceptive - has protective element integral with fixing element, which may be knotted, which is inserted by plunger or trigger-operated rod
IPC: A61F6/14
Filed: 1984-03-29
Abstract: The device for fitting an intra-uterine contraceptive device immediately after childbirth, uses a fixing element (10) which is integral with both the contraceptive device (9) and the insertion device (2). A protective element (4) is integral with the fixing device and can be removed after fitting. The device may have a knot in the fixing thread, to ensure that it will remain in place. - The device may be inserted by means of a plunger or by a trigger-operated rod. Notches may be used to limit the depth of insertion into the wall of the uterus. A needle of various designs may be used to hold the thread.
Patent BE-899597-A (BE)
Title: Low carbohydrate powder dessert mix - contg. cold soluble calcium caseinate, wheat protein, gelatin, soya flour, salt and flavourings
IPC: A21D2/26
Filed: 1984-05-07
Abstract: A powder mixt. is made comprises predominantly of cold-soluble calcium caseinate, wheat protein, gelatin, soya flour, salt and flavourings. Pref. (i) the cold soluble animal protein pref. forms a dough-like structure; (ii) during baking no yeast is added but the prod. gives a structure resembling that of yeast risen material; (iii) pref. the powder mixt. contains only traces of carbohydrates in the form of starch and its derivs. or simple or complex sugars, and any addn. of these is avoided.
Patent BE-899700-A (BE)
Title: Dispositif d'essuyage pour glaces de vehicules automobiles, a pression d'application a plusieurs points d'impact.
IPC: B60S1/38
Filed: 1984-05-18
Abstract: Dispositif caractérisé en ce que, sur la baguette élastique (28) vient en prise un système d'étrier porteur (20) en au moins deux parties, qui comporte des moyens pour raccorder la raclette d'essuyage (14) à un bras entrainé d'essuie-glace. L'invention s'applique aux essuie-glace de voitures automobiles.
Patent BE-905398-A (BE)
Title: Procede pour chauffer une chaussee par la chaleur interne du sol et installation pour la mise en oeuvre de ce procede.
Inventor: BAHRLE F
IPC: F24J3/08
Filed: 1986-09-08
Abstract: Cette installation comprend des tubes échangeurs de chaleur (1,1',1'') qui longent la surface (26) de la chaussée et plongent dans le sol et elle est équipée d'un appareil de commande (19)  qui agit en fonction des conditions météorologiques. Pour éviter de prélever inutilement de la chaleur dans le sol, on commande la capacité de transmission de chaleur des tubes échangeurs de chaleur (1,1',1'') par un blocage réversible des zones de condensation (14) de ces tubes (1,1',1''), ce blocage étant obtenu en introduisant dans ces zones un gaz inerte, en une quantité réglable de l'extérieur.
Patent BE-905808-A (BE)
Title: Random number selector - uses balls and cells numbered according to signs of zodiac
IPC: A63F7/04
Filed: 1986-11-24
Abstract: The small circular apparatus has a flat base containing several of hollow cells. There are also several balls, made of metal or plastics material which are contained in the apparatus. - The cells are numbered and the numbers vary according to one of the twelve signs of the zodiac and are based on astrological facts. The balls fall into some of the cells and the numbers on these cells determine the numbers to be used.
Patent BE-905818-A (BE)
Title: Complexes de succinimides et d'alcoylcatechols borates et compositions d'huiles lubrifiantes les contenant.
IPC: C10M141/00
Filed: 1986-11-27
Abstract: Des huiles lubrifiantes additionnées d'un complexe succinimide-alcoylcatéchol boraté sont efficaces pour réduire la consommation de carburant dans  les moteurs à combustion interne à allumage par compression ou par bougies. Avantageusement, le radical alcoyle de l'alcoylcatéchol boraté compte 10 à 30 atomes de carbone et le succinimide est un polyisobuténylsuccinimide issu de la triéthylènetrétamine ou un polyisobuténylsuccinimide : issu de la tétraéthylènepentamine.
Patent BE-775071-A (BE)
Title: Meat flavour/colour developer - consisting of ascorbic acid reducing sugar, amino acid and complexing agent
IPC: A23B4/12
Filed: 1971-11-08
Abstract: Additive for meat products consists of a powdered mixture of ascorbic acid or one of its salts, with reducing sugars, amino acids and/or nucleotides, and a complexing cpd. Used in e.g. mince, fillet steak and sausage, in order to fix and develop the taste, aroma and colour.
Patent CA-1043390-A (CA)
Inventor: BOMBARDIER JEROME
IPC: B60J1/02
Filed: 1974-10-08
Granted: 1978-11-28
Abstract: A B S T R A C T A snowmobile windshield comprises a mouled sheet of transparent polycarbonate material having a series of mounting tabs spaced along its lower edge.   The mounting tabs are of resilient form, being integral with the wind-shield and generally flat, but having laterally extending parts which can be compressed together to allow the tab to pass into engagement with a narrow mounting slot in the cab of the snowmobile.   The windshield can be installed without requiring access to the underside of the snowmobile cab, and in accident conditions can yield by releasing the tabs from their mounting slots, thereby reducing the likelihood of facial injuries to the snowmobile driver.
Patent CA-1052785-A (CA)
Inventor: MICHNE WILLIAM F
IPC: A61P25/04
Filed: 1975-05-20
Granted: 1979-04-17
Abstract: ABSTRACT OF THE DISCLOSURE 6(eq)-R4-1,2,3,4,5,6-Hexahydro-3-R1-11(ax)-R3-11(eq)-CH2Z-2,6-methano-3-benzazocine, useful as analgesic agents and narcotic antagonists, and 1-R1-2-Q-4?-R3-5.alpha.-R4-1,2,3,4,4a,5,10,-10a-octahydro-3,5-etheno- (and 3,5-ethano) benzo[g]quinolines, use-ful as analgesic agents, the former being prepared by heating, with formic acid in an organic solvent or with certain ammonium formates in the absence of a solvent, certain 1,2,3,4,4a,5,10,10a-octahydro-2,5-methanobenzo[g]quinolines, the latter being prepared by acid catalyzed cyclization of a 3-benzyl-2-azabicyclo[2.2.2]oct-5-ene.
Patent CA-1052653-A (CA)
Inventor: O'LEARY STEPHEN H
IPC: A61M5/145
Filed: 1975-06-06
Granted: 1979-04-17
Abstract: ABSTRACT OF THE DISCLOSURE            This invention relates to a new and improved drive system and syringe for syringe pumps, wherein a disposible syringe cartridge having no valves is reliably and precisely mounted, monitored, and driven through repetitive fill and pump strokes.  Prior art disposable syringes are com-plex and expensive and prone to leakage.  Additionally, they are difficult to mount and remove.  The present invention overcomes these deficiencies by providing a syringe cartridge which has no valves, and the apparatus repetitively and sequentially opens and closes, by means of an external pair of tube pinchers, a pair of intake and output I.V. tubes communicating with the inlet and outlet nipples.  The cartridge includes a molded plastic cylinder having inlet and outlet nipples, a plastic piston and piston rod, and a rubber sealing cap defining a conical piston face, a pair of piston sealing rings and a sealing boot.
Patent CA-1044265-A (CA)
Inventor: ZAHID ABDUZ
IPC: F16F9/44
Filed: 1975-07-08
Granted: 1978-12-12
Abstract: Abstract of the Disclosure This invention relates to a shock absorber of the type comprising a cylindrical outer casing open at one end and closed at the other end, the closed end having an axial port. Positioned in the outer casing and extending longitudinally thereof is an inner casing of smaller diameter than the outer casing to define a chamber therebetween, the inner casing having one end open and the other end closed and longitudinally spaced from the end of the outer casing. A bladder of resilient material encompasses the major portion of the length of the inner casing and the closed end of the bladder mounts a valve member which is axially aligned with an axial bore in the closed end of the inner casing and normally urged against the valve seat defined by the outer end of said axial bore.    Adjustment means accessible from the exterior, through the axial port in the closed end of the outer casing is provided to determine the amount of movement of the valve means away from the valve seat defined at the outer end of the axial bore in the closed end of the inner casing.    The bladder is mounted on an annular supporting member positioned between the outer and inner casing at the mouths thereof and a plug is provided to seal the mouth of the inner casing.    A piston is slidably mounted in the inner casing and has an axially extending piston rod secured at one end thereto with the other end of the piston rod protruding through an axial bore in the plug and normally resiliently urged outwardly.         The piston rod has valve controlled means to permit flow of fluid from the portion of the inner casing bore adjacent the closed end of such bore to the portion of the inner casing bore on the other side of the piston and to restrain flow in the opposite direction. In addition perforations are provided in the wall of the inner casing to permit flow of fluid from one side of the piston through the perforations to the other side of the piston.
Patent CA-1049166-A (CA)
Inventor: WEIGEL MORTON L
IPC: H03J5/06
Filed: 1975-08-07
Granted: 1979-02-20
Abstract: DETENT UHF TUNER WITH PRESET MEMORY                 Abstract of the Disclosure A detent type tuning mechanism for a UHF tuner having a continuously variable tuning shaft includes a detented selector shaft, a gear train interconnecting the tuner shaft and the selector shaft, and a memory type fine tuning mechanism including a rotatable turret having mounted thereon a plurality of cams each engageable by a fine tuning shaft when the selector shaft is positioned in predetermined ones of the detent positions.  Each cam serves as a memory fine tuning system for a predetermined group of adjacent UHF channels.  A cam follower interconnects one of the cams and the tuning shaft, and serves to rotate the tuning shaft in response to the rotation of one of the cams by the fine tuning shaft.  An indicator dial provides a numerical dis-play of the precise UHF channel selected at each position of the detented selector shaft.
Patent CA-1054712-A (CA)
Title: Compensation element for dynamic semiconductor stores, and method of operating the same
Inventor: MEUSBURGER G
IPC: G11C11/4099
Filed: 1975-08-27
Granted: 1979-05-15
Abstract: ABSTRACT           The invention relates to a dummy cell for a dynamic semiconductor store, employing an evaluator circuit and con-nected therewith bit lines and storage elements adapted to be selectively connected therewith.  The dummy cell may be selected through a dummy cell selector line and in its selected stage is connected to any bit line which is not busy with the read-out of a storage element.  The dummy cell comprises a dummy cell condenser through which any connected bit line re-ceives a correcting voltage raising its potential to a middle potential of UBD= 0.5 (UBO+ UBl).   UBO corresponds to the read-out voltage on the bit line during the read-out of a binary "O" and UBl corresponds to the read-out voltage on the bit line during the read-out of a binary "1".  This mode of operation increases the read-out sensitivity.
Patent CA-1082177-A (CA)
Title: 1-methyl-4-(3-carboxy-10,11-dihydro-5h-dibenzo a,d cyclohepten-5-ylidene)piperidine and its n-oxide
Inventor: REMY DAVID C
IPC: A61P1/14
Filed: 1975-10-27
Granted: 1980-07-22
Abstract: ABSTRACT OF THE DISCLOSURE   10,11-Dihydro-3-carboxycyproheptadine and its esters, amides and N-oxide are disclosed to have pharmaceutical utility as appetite stimulants and as antihistaminic agents. Also disclosed are processes for the preparation of such compounds; pharmaceutical compositions comprising such, compounds; and methods of treatment comprising administering such compounds and compositions.
Patent CA-1074010-A (CA)
Title: Apparatus and method for a digital readout of a distance traveled, fuel consumed and miles per gallon of a moving motor vehicle
Inventor: KLAVER RUDOLF F
IPC: G01F9/00
Filed: 1975-11-04
Granted: 1980-03-18
Abstract: ABSTRACT OF THE DISCLOSURE          APPARATUS AND METHOD FOR A DIGITAL READOUT OF DISTANCE TRAVELED, FUEL CONSUMED AND MILES     PER GALLON OF A MOVING MOTOR VEHICLE          The apparatus gives a simultaneous readout of the semi-instantaneous rate of fuel consumption, expressed in terms of miles per gallon; the distance traveled; and the total amount of gallons consumed since the apparatus was last reset for a moving vehicle powered by an internal combustion engine.  The fuel is metered by a flow transducer which emits a pulse rate representative of fuel flow rate while at the same time the miles traveled by the moving vehicle are measured by a distance transducer also emitting a pulse rate. Both pulse rates are fed to digital integrated circuitry that provides readouts for miles traveled, total fuel consumed and for the semi-instantaneous miles per gallon.          The apparatus also includes a reset switch, a hold switch to maintain the indicator readings while not inhibiting the accumula-tion of further counts, and internal switches to accommodate vehicle-to-vehicle variations in rear end ratios and tire sizes.          The method comprise the steps of generating a first series of pulses related to fuel flow to the engine so that a predetermined amount of fuel is consumed by the engine prior to emission of a pulse;   generating a second series of pulses related to the distance traveled by the vehicle; summing and displaying a sum of all the second-series pulses accumulated before a pulse emission from the first series.          This displayed sum is then replaced by a subsequent sum accumulated up to emission of a respective subsequent pulse from the first series.        Other steps include summing and displaying the entire first and second pulse series to respectively represent total fuel consumed and total miles traveled.