baber/WOPTO huggingface dataset:
Patent ZA-200002151-B (ZA)
Title: 1-AZA-2-alkyl-6-aryl-cycloalkane compounds, a process for their preparation and pharmaceutical compositions containing them.
Inventor: RAULT SYLVAIN
IPC: A61K31/395
Filed: 2000-05-03
Abstract: 1-Aza-2-alkyl-6-aryl cycloalkanes (I) are new. 1-Aza-2-alkyl-6-aryl cycloalkanes of formula (I), their isomers and acid addition salts, are new. n = 0 or 1; R1 = H, aryl-1-6C alkyl, 1-6C alkyl or acyl, 1-6C alkoxycarbonylaryl-1-6C alkoxy carbonyl, or CF3; R2 = 1-6C alkyl; X = O, Cl, OR3, SR4, or NOR5; R3 = H, 1-6C alkyl or acyl, 1-6C alkoxycarbonyl, or aryl 1-6C alkoxycarbonyl; R4 = H, 1-6C alkyl, or aryl; R5 = H, 1-6C alkyl(optionally substituted by one or more groups selected from OH, amino that may be substituted by one or two alkyl groups, or 1-6C alkoxy; the dotted line = an optional bond; and Ar = aryl or heteroaryl; with the proviso that (I) is not any of the following: 6-methyl-2-phenyl-2,3-dihydro-4-pyridinone; 2-methyl-6-phenyl-4-piperidinone; N-benzyl-2-(R'2)-6-phenyl-4-piperidinones where R'2 is methyl, ethyl, propyl, or isopropyl; or 2-(R2)-6-phenyl-4-piperidinols where R2 is isopropyl or butyl.
Patent ZA-200100022-B (ZA)
Title: Linear or cyclic ureas, a process for their preparation and pharmaceutical compositions containing them.
Inventor: PEGLION JEAN-LOUIS
IPC: A61K31/4427
Filed: 2001-01-02
Abstract: Piperidinyl- or piperazinyl-substituted linear or cyclic urea derivatives (or analogs) (I) are new. Piperidine or piperazine derivatives of formula (I) and their isomers, hydrates, solvates and acid addition salts are new. [Image] V, M : direct bond or linear or branched 1-6C alkylene; A, E : N or CH, provided that at least one is N; W : diaza-cyclic group of formula (a) or bicyclic group of formula (b), or may also be a bicyclic group of formula (c) if V = direct bond and A = N; [Image] * : attachment point; X : CO, SO or SO 2; G 12-4C n-alkylene (optionally containing a double bond and/or substituted by OH); G 2direct bond; and G 32-3C n-alkylene (optionally containing a double bond); or G 2CH 2; and G 31-2C n-alkylene (optionally containing a double bond); T : fused benzene or pyridine ring; R 1H, alkyl, Ar or Ar-alkyl; R 2 a, R 2 bH, halo, alkyl, OH, alkoxy, SH, alkylthio, trihaloalkyl, CN, NO 2, NH 2, mono- or dialkylamino, trihaloalkoxy, Ar-alkoxy, alkylsulfonate, trihaloalkylsulfonate or alkylsulfonyl; or R 2 a + R 2 bOCH 2O, O(CH 2) 2O, O(CH 2) 3O or CH 2CH 2 (optionally substituted by CN, CH 2OH, alkoxycarbonyl, ArOCO, or Ar-alkoxycarbonyl); R 3Ar or Het 1 (both optionally substituted by one or more R 2 a); Y : OAr, OHet 1 or Het 2 (all optionally substituted by one or more R 2 a); Ar : phenyl, biphenyl, naphthyl, dihydronaphthyl, tetrahydronaphthyl, indanyl, indenyl or benzocyclobutyl; Het 15-12 membered mono- or bicyclic aromatic system containing 1 or 2 of O, S and N as heteroatom(s), where in the case of bicyclic systems one of the rings may be partially hydrogenated; and Het 25-12 membered mono- or bicyclic aromatic system containing 1-3 of O, S and N as heteroatom(s). alkyl moieties have 1-6C unless specified otherwise; provided that: (i) if V = direct bond, W = (a) and R 3 = Ph, then Y cannot be 3-indolyl; (ii) if M = direct bond, W = (a) and Y = bicyclic Het 2 in which one ring is a benzene ring, then Y cannot be bonded to M via this benzene ring; and (iii) if M = direct bond, V = CH 2CH 2, W = (a) and R 3 = Ph, then Y cannot be 1,2-benzisoxazol-3-yl. An independent claim is included for the preparation of (I). ACTIVITY : Vasotropic; antiarteriosclerotic; cardiant; hypotensive. MECHANISM OF ACTION : Endothelial nitrogen monoxide (NO) synthase inhibitor antagonist; superoxide antagonist; antioxidant. (I) reduce endothelial dysfunction and reduction in vascular NO availability induced by inhibition of endothelial NO synthase or by oxidative stress associated with production of superoxide anion. In tests in rat aortic rings, N-(2-(4-(phenoxymethyl)-1-piperidinyl)-ethyl)-1-indoline-carboxamide (Ia) at a concentration of 30 nM gave 26 % inhibition of endothelial dysfunction induced by the NO synthase inhibitor N(G)-nitro-L-arginine.
Patent ZA-200104202-B (ZA)
Title: Device and method for locating and resecting bone.
Inventor: TROXELL THOMAS N
IPC: A61B17/56
Filed: 2001-05-23
Abstract: A device and method for the location of a pedicle and resection of the corresponding lamina are disclosed. The device includes an osteotome having a cutting element configured and dimensioned to remove a section of bone sized to accommodate a portion of an implant; and a pedicle finder having a handle at a proximal end for manipulation of the pedicle finder, a pedicle locator at a distal end connected to the handle by a shaft, and a osteotome guide located on the shaft configured and dimensioned to slidingly engage at least a portion of the osteotome. By providing the osteotome guide on the same device as the pedicle locator and configuring the cutting element of the osteotome and osteotome guide to remove a fixed section of bone, the size and position of the resected bone is optimized to help ensure proper seating of an implant such as a pedicle hook.
Patent ZA-200206800-B (ZA)
Title: Method and device for determining the state of a rail stretch.
Inventor: PFENNIGER ERICH
IPC: B66B7/12
Filed: 2002-08-26
Abstract: A lift guide rail monitoring unit has a receiver (E) moving over the guide rail bundle (SS) to measure distances (AD) from groups of transmitters (S1, S2, S3) for position triangulation.
Patent ZA-200209603-B (ZA)
Title: Defense device, preferably self-defense device and storage unit used therein.
Inventor: FLEISCHHAUER RAPHAEL
IPC: F41H9/10
Filed: 2002-11-26
Abstract: The accumulator unit (1) with a powder, gaseous or liquid material stored in an accumulator space (5). A propellant is ignited by a fuse composition to drive the material through a nozzle unit (3) into free space by a propellant gas after ignition. A closure element (19) in the nozzle entry area prevents material from coming out of the accumulator space without ignition and is released directly after ignition so that no parts of the broken closure element are pushed out of the nozzle unit. A piston (21) in the accumulator space is moved by the propellant gas to drive the material through the nozzle. A pressure relief device co-operates with the piston. An Independent claim is included for a self-defence device including at least one pair of accumulator units.
Patent ZA-200610345-B (ZA)
Title: Piperazine derivatives of alkyl oxindoles
Inventor: BALASZS VOLK
IPC: C07D209/34
Filed: 2005-05-11
Abstract: The present invention is concerned with new indol-2-one derivatives of Formula (I), which have favorable activity profile for the prophylaxis and treatment of disorders in the central nervous or in the cadiovascular system.
Patent ZA-200709095-B (ZA)
Title: Apparatus for determining the intrinsic speed of a watercraft
Inventor: NILS THEUERKAUF
IPC: G01S/
Filed: 2007-10-22
Abstract: The apparatus uses an antenna (111,112,113,114) on the vehicle made up of several equidistantly spaced broadband electroacoustic converters. All the converters (13) are divided into parallel operated groups having the same number of converters. The converters within a group can be combined into subgroups for parallel operation. The converters in the groups are operated with a first transmission frequency and those in the subgroups with a second transmission frequency which is a whole number multiple of the first frequency. The multiple is determined by the number of subgroups in each group.
Patent CL-43473-B (CL)
Inventor: LOEBNER ANDREAS PULLENBERG REI
IPC: F24D9/00
Filed: 2004-05-19
Granted: 2005-02-04
Abstract: A process container comprising a metallic casing having at least one refractory cladding layer disposed on the inner side thereof, and cooling elements connected to the outer side of the casing. Each cooling element comprises a base plate and at least one cooling channel connected to the base plate in a heat-conducting manner. The base plate is connected to the outer side of the casing by being screw connected to threaded bolts welded onto the outer side of the casing whereby the base plates nestle against the casing by flexural deformation due to clamping pressure of the screw connections. Ends of the cooling channels are connected to ends of adjacent cooling channels.
Patent MX-340895-B (MX)
Title: Hip joint device and method.
Inventor: PETER FORSELL
IPC: A61F2/32
Filed: 2010-07-12
Abstract: A medical device for implantation in a hip joint of a patient, the natural hip joint having a ball shaped caput femur integrated with a collum femur having a collum and caput center axis, extending longitudinal along the collum and caput femur, in the center thereof, as the proximal part of the femoral bone with a convex hip joint surface towards the centre of the hip joint and a bowl shaped acetabulum as part of the pelvic bone with a concave hip joint surface towards the centre of the hip joint, the medical device comprising; an artificial caput femur comprising a convex surface towards the centre of the hip joint, an elongated portion adapted to be connected to a prosthetic spherical portion of said artificial convex caput femur and fixated to the pelvic bone of the human patient.
Patent MX-358324-B (MX)
Title: Dry toilet.
Inventor: RAFAEL MIER MAZA
IPC: A47K11/02
Filed: 2012-01-24
Abstract: The present invention refers to a device for treating household wastes by means of composting. The wastes are collected in a conventional manner in a toilet bowl, in which the liquid are drained by a conduit so as to be disposed and the solids moved by gravity to a mixing drum; in the inner portion of the drum, an amount of composting additive is sifted over the surface of the solids in a tray that is moved from a position between the bowl and the mixing drum and a second position under the additive container, the solids being mixed with the additive by means of a mixer manually operated through a crank. In connection with the mixing drum, a discharge is performed in the compost container from which the compost is periodically removed. The composting additive is stored in a deposit behind the toilet bowl and over the compost collector, and is discharged to the tray by gravity each time the mixing tank is opened by the user when using the toilet, the additive being sifted over the soli d waste in the mixing tank when the tray is moved above said mixing tank.
Patent MX-339031-B (MX)
Title: Modified vasoactive intestinal peptides.
Inventor: SADEGHI HOMAYOUN
IPC: A61K38/22
Filed: 2010-08-16
Abstract: The present invention provides modified Vasoactive Intestinal Peptides (VIPs), encoding polynucleotides and vectors, as well as pharmaceutical compositions comprising the same. The invention further provides methods of making and using the modified VIP agents. In accordance with the invention the VIP exhibits an extended circulatory half-life, receptor-binding or biological potency, and/or altered receptor binding profile with respect to unmodified VIP.
Patent MX-341178-B (MX)
Title: Methods for determining gene-nutrient interactions.
Inventor: ROSALYNN D GILL
IPC: C12Q1/68
Filed: 2011-02-24
Abstract: The present invention provides methods and tests that allow for the establishment of personalized weight-management programs for an individual based upon the individual's genotype in the glutathione S-transferase pi gene and/or the interleukin-6 gene. Methods are disclosed for determining the individual's genotype, which may be used to select an appropriate therapeutic/dietary program or lifestyle recommendation. Such a personalized weight-management program will have obvious benefits (e.g., yield better results in terms of weight loss and weight maintenance) over traditional weight-management programs that do not take into account genetic information.
Patent MX-346673-B (MX)
Title: Compounds, compositions, and methods for reducing or eliminating bitter taste.
Inventor: SLADE LOUISE
IPC: A23L27/40
Filed: 2011-04-15
Abstract: The present invention provides edible compositions comprising a compound of the present invention, food products comprising such edible compositions and methods of preparing such food products. The present invention also provides methods of reducing the amount of NaC1 in a food product, methods of reducing the sodium intake in a diet, and methods of reducing bitter taste in a food product.
Patent MX-337260-B (MX)
Title: Metering valve for pressurized vial.
Inventor: BODET HERVÉ
IPC: B65D83/14
Filed: 2011-07-26
Abstract: The invention relates to a metering valve (1) for a pressurized vial, comprising a valve body (9) in which a valve element (4) can slide, a metering chamber (7) and means for moving the valve element (4) between a closed position in which, when mounted on a vial, the metering chamber (7) is in contact with the inside of the vial and isolated from the outside of the vial, and an open position in which, when mounted, the metering chamber (7) is isolated from the inside of the vial and in contact with the outside of the vial. According to the invention, the metering chamber (7) is fixed by its upper end to that part of the valve body (9) which, when mounted, is situated inside the vial, an inlet passage being provided that places the inside of the vial in contact with the metering chamber and an outlet passage being provided that places the metering chamber in contact with the outside of the valve, inlet shut-off means being provided to shut off the inlet passage when the valve element (4) is in the open position and outlet shut-off means being provided to shut off the outlet passage when the valve element (4) is in the closed position. In addition, the valve element can be moved beyond the open position into a third position, known as the short-circuit position, a third passage known as short-circuit passage, being provided to place the inside of the vial in contact with the outside of the vial, short-circuit shut-off means being provided for shutting off the short-circuit passage when the valve element (4) is in the closed position or in the open position.
Patent MX-345501-B (MX)
Title: Solid compositions comprising a glp-1 agonist and a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid.
Inventor: PER SAUERBERG
IPC: A61K38/26
Filed: 2011-12-16
Abstract: The present invention relates to solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid and their use in medicine.
Patent MX-350003-B (MX)
Title: Process for the manufacture of dibenzoylmethane derivatives.
Inventor: CHRISTOF WEHRLI
IPC: C07C45/45
Filed: 2011-12-19
Abstract: The invention relates to a process for the manufacture of substituted dibenzoylmethane derivatives. This economical process provides products in high purity and yields and results in shorter reaction times.
Patent MX-348079-B (MX)
Title: Topical localized isoxazoline formulation comprising glycofurol.
Inventor: FUCHS STEFAN
IPC: A61K31/42
Filed: 2011-12-22
Abstract: This invention provides topical localized formulations comprising an isoxazoline compound and a pharmaceutically or veterinary acceptable liquid carrier vehicle comprising glycofurol and an improved method for controlling, and preventing parasite infestation in animals.
Patent MX-365504-B (MX)
Title: Transparent infrared absorbing materials.
Inventor: WAYNE KEVIN JACKSON
IPC: C08K9/04
Filed: 2012-02-01
Abstract: An infrared absorbing material, an infrared absorbing ink formulation and a method of production are provided in which at least one infrared absorbing dye is supported on nanoparticles having an average size not greater than 100nm in at least one direction. The dye-supporting nanoparticles may be dispersed in a carrier vehicle such that the infrared absorbing material or ink is substantially transparent to visible radiation. The infrared absorbing material and ink are particularly suitable for use in banknotes and other security documents.
Patent MX-336130-B (MX)
Title: Oxidative dyeing compositions comprising an 1-hexyl/heptyl-4,5-di aminopyrazole and a benzene-1,3-diol and derivatives thereof.
Inventor: LIM MUILL
IPC: A61K8/34
Filed: 2012-02-16
Abstract: An oxidative dyeing composition comprising (A) a 1-hexyl/heptyl-4,5-diaminopyrazole compound of the general formula (I), its physiologically compatible water-soluble salt, or mixtures thereof; (B) a benzene-1,3-diol compound of the general formula (II), its physiologically compatible water-soluble salt, or mixtures thereof, and (C) an oxidizing agent. wherein R1, R2, R3, R4, R5, R6 and R7 are as defined herein and a = 1 or 2.
Patent MX-350976-B (MX)
Title: Frictional weld joint for an article comprising a thermoplastic material.
Inventor: ANKUR M BHOSALE
IPC: B32B37/30
Filed: 2012-05-23
Abstract: A frictional weld joint couples first and second body portions of an article together. The frictional weld joint comprises a first bead extending from the first body portion of the article and a second bead extending from the second body portion of the article. The second bead has an interior stem and an exterior stem space from the interior stem defining a cavity therebetween. The first and second beads are placed in contact with each other with the centerline of the second bead offset from the centerline of the first bead. A force is applied to either the first or second body portions to generate friction between the first and second beads to plastically displace the first and second beads. The force is removed for fusing the first and second beads together to couple together the first and the second body portions of the article.
Patent MX-342078-B (MX)
Title: Edge gesture.
Inventor: JENNIFER NAN
IPC: G06F3/03
Filed: 2011-10-09
Abstract: This document describes techniques and apparatuses enabling an edge gesture. In some embodiments, these techniques and apparatuses enable selection of a user interface not currently exposed on a display through an edge gesture that is easy-to-use and remember.
Patent MX-336588-B (MX)
Title: Improved blowout preventer.
Inventor: PENDLETON GARY
IPC: E21B33/06
Filed: 2012-06-08
Abstract: A blowout preventer comprising: a main body comprising a seal seating profile, one or more bonnet guideways, and one or more slide guideways; a bonnet attached to the main body, wherein the bonnet comprises one or more guide rods, a ram unit, and a seal seating profile; two retention units attached to the main body and the bonnet, wherein each retention unit comprise a clamp block, one or more guide rods, and a bonnet guideway; and a metal seal, wherein the metal seal is seated in the seal seating profile of the main body and the seal seating profile of the bonnet.
Patent MX-357036-B (MX)
Title: Enzymatically inverted saccharose as a dispersant.
Inventor: SCHOBER IRENE
IPC: C04B24/10
Filed: 2012-08-16
Abstract: An enzymatically inverted saccharose is used as a dispersant for a mineral binder.
Patent MX-363351-B (MX)
Title: Methods for treating vascular leak syndrome and cancer.
Inventor: ROBERT SHALWITZ
IPC: C07K16/28
Filed: 2012-10-15
Abstract: Disclosed are methods for treating Vascular Leak Syndrome and preventing cancer metastasis. Further disclosed are methods for treating vascular leakage due to inflammatory diseases, sepsis, cancer or the presence of pathogens.
Patent MX-349514-B (MX)
Title: Anticoagulant reversal agents.
Inventor: SOLOMON S STEINER
IPC: A61K31/495
Filed: 2012-11-29
Abstract: Novel anticoagulant reversal compounds are disclosed, as well as methods of making the compounds, pharmaceutical compositions including the compounds, methods of using the compounds to reverse the anticoagulant effects of coagulation inhibitors, and diagnostic assays comprising the compounds.
Patent MX-350693-B (MX)
Title: Patterned candle wick.
Inventor: SPANGLER MARK A
IPC: C11C5/00
Filed: 2012-12-14
Abstract: A substantially planar wick is formed with a two- or three-dimensional pattern. The contours of this pattern are determined by the desired flame characteristics or the desired visual aesthetics of the pattern itself.
Patent MX-348965-B (MX)
Title: Character selection method and apparatus and terminal device.
Inventor: JINGLONG ZUO
IPC: G06F3/0488
Filed: 2014-05-09
Abstract: Disclosed are a character selection method and apparatus and a terminal device. The method comprises the following steps: detecting whether a contact of a touchscreen operation for selecting a character falls in a text node or not; when the contact does not fall in the text node, searching for a text node having the shortest distance from the contact; and using a character having the shortest distance from the contact in the found text node as a character selected by the contact. In the present disclosure, when a contact of a touchscreen operation for selecting a character does not fall in a text node, a character having the shortest distance from the contact in a text node having the shortest distance from the contact is used as a character selected by the contact, and therefore, it is achieved that when the contact does not fall on a character, the character selected by the touchscreen operation can also be provided, so that a user is prevented from conducting selection repeatedly, thereby providing convenience for the user.
Patent MX-353190-B (MX)
Title: Isoquinoline and naphthyridine derivatives.
Inventor: HUIFEN CHEN
IPC: A61K31/4725
Filed: 2013-01-29
Abstract: The invention provides novel compounds having the general formula<i/>(I) wherein A, R1 and R2 are as described herein, compositions including the compounds and use of the compounds for inhibiting angiogenesis by inhibition of MAP4K4.
Patent MX-353554-B (MX)
Title: Method and device for determining position.
Inventor: PAN JUN
IPC: G06F17/30
Filed: 2014-10-22
Abstract: Disclosed are a method and device for determining a position, which belong to the technical field of computers. The method comprises: when a position request of a designated application is detected, acquiring a position coordinate thereof through a positioning function; querying the designated region to which the position coordinate belongs in a correlation between a pre-stored position coordinate range and a designated region; and according to the designated region to which the position coordinate belongs, responding to the position request of the designated application. Compared with the technology in the related art for sending a position coordinate to a third-party application to determine a specific position, the embodiments of the present disclosure can respond to a position request of a designated application without invoking the third-party application or accessing a network application, thereby improving the efficiency of responding to the position request of the designated application.
Patent MX-357484-B (MX)
Title: Amylase-deficient strain.
Inventor: NOËL NICOLAAS MARIA ELISABETH VAN PEIJ
IPC: C12N15/80
Filed: 2013-07-19
Abstract: The present invention relates to a mutant microbial host cell which has been modified, preferably in its genome, to result in a deficiency in the production of a polypeptide having a-amylase activity AmyC or an homologous thereof. It has been surprisingly found that when the mutant microbial host cell according to the invention is used in a method to produce a compound of interest, for example an enzyme, an improved purity of the product is obtained.