baber/WOPTO huggingface dataset:
Patent EP-1274473-B2 (EP)
Inventor: BURRELL ROBERT EDWARD
IPC: A61K33/24
Filed: 2001-04-17
Granted: 2011-04-13
Abstract: The invention provides bioabsorbable materials with antimicrobial coatings or powders which provide an effective and sustainable antimicrobial effect. Specifically, this invention provides bioabsorbable materials comprising a bioabsorbable substrate associated with one or more antimicrobial metals being in a crystalline form characterized by sufficient atomic disorder, such that the bioabsorbable material in contact with an alcohol or water based electrolyte, releases atoms, ion, molecules, or clusters of at least one antimicrobial metal at a concentration sufficient to provide an antimicrobial effect. The one or more antimicrobial metals do not interfere with the bioabsorption of the bioabsorbable material, and do not leave behind particulates larger than 2 mum, as measured 24 hours after. The bioabsorbable material has disappeared. Most preferably, the particulate sizing from the coating or powder is sub-micron that is less than about 1 mum, as measured 24 hours after the bioabsorbable material has disappeared. Particulates are thus sized to avoid deleterious immune responses or toxic effects. Such antimicrobial metals are in the form of a continuous or discontinuous coating, a powder, or a coating on a bioabsorbable powder. The antimicrobial coating is thin, preferably less than 900 nm or more preferably less than 500 nm, and very fine grained, with a grain size (crystallite size) of preferably less than 100 nm, more preferably less than 40 nm, and most preferably less than 20 nm. The antimicrobial coating is formed of an antimicrobial metal, which is overall crystalline, but which is created with atomic disorder, and preferably also having either or both of a) a high oxygen content, as evidenced by a rest potential greater than about 225 mV, more preferably greater than about 250 mV, in 0.15 M Na2CO3 against a SCE (standard calomel electrode), or b) discontinuity in the coating. The antimicrobial metal associated with the bioabsorbable substrate may also be in the form of a powder, having a particle size of less than 100 mum, or preferably less than 40 mum, and with a grain size (crystallite size) of preferably less than 100 nm, more preferably less than 40 nm, and most preferably less than 20 nm, Such powders may be prepared as a coating preferably of the above thickness, onto powdered biocompatible and bioabsorbable substrates; as a nanocrystalline coating and converted into a powder; or as a powder of the antimicrobial metal which is cold worked to impart atomic disorder. Methods of preparing the above antimicrobial bioabsorbable materials are thus also provided.
Patent EP-1368019-B2 (EP)
Inventor: LIU JIE
IPC: A61K9/08
Filed: 2002-01-02
Granted: 2010-06-02
Abstract: An aqueous, sterile pharmaceutical composition suitable for parenteral administration for the treatment of cardiac conditions, comprising methyl-3-[4-(2-hydroxy-3-isopropylamino) propoxy] phenylpropionate hydrochloride (esmolol hydrochloride), a buffering agent and an osmotic-adjusting agent, as well as a method for its manufacture, are disclosed.
Patent EP-1483294-B2 (EP)
Inventor: HANSEN HANS
IPC: A61K39/395
Filed: 2003-03-03
Granted: 2019-10-30
Abstract: The present invention provides humanized, chimeric and human anti-CD74 antibodies, CD74 antibody fusion proteins, immunoconjugates, vaccines and bispecific that bind to CD74, the major histocompatibility complex (MHC) class-II invariant chain, Ii, which is useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies, other malignancies in which the cells are reactive with CD74, and autoimmune diseases, and methods of treatment and diagnosis.
Patent EP-1635977-B2 (EP)
Inventor: RIVIERE BERTRAND
IPC: B23C5/10
Filed: 2004-03-16
Granted: 2018-10-17
Abstract: The present invention relates to an indexable cutting insert for an end mill for machining of contours in a workpiece and to a milling tool. The cutting insert is asymmetrical in respect of a line through a hole in the cutting insert. The cutting insert includes two cutting edge portions. Each cutting edge portion comprises of a substantially straight cutting edge and a curved cutting edge along respective intersecting lines between a clearance surface and a chip surface. The curved cutting edges have different lengths. The cutting insert includes recesses in a bottom side of the cutting insert. The recesses are arranged on both sides of and at different distances from the hole of the cutting insert.
Patent EP-0285682-B2 (EP)
Inventor: SCIALPI LEONARD JOSEPH
IPC: A23K20/174
Filed: 1987-04-06
Granted: 1997-08-06
Abstract: A process is described for the manufacture of preparations in beadlets form containing fat soluble vitamins and/or carotenoids. which exhibit outstanding stability when exposed to feed pelleting processes.
Patent EP-0476835-B2 (EP)
Inventor: MARTENS ANDRE
IPC: C08F10/00
Filed: 1991-08-16
Granted: 2000-09-13
Abstract: A continuous process (I) for the polymerisation of a 2-12C is carried out in a gas phase polymerisation reactor by bringing a gaseous reaction mixture contg. olefin (II) into contact with a catalyst system (III) of the Ziegler-Natta type consisting of a solid catalyst consisting (A) at least one cpd. of a transition metal belonging to gps. IV, V or VI of the Periodic Table of elements and of a (B) cocatalyst comprising at least one organometallic cpd. of a metal belonging to gps. II or III of the Periodic Table. In (I), (II) is fed into the polymerisation reactor at a constant rate.
Patent EP-0683735-B2 (EP)
Inventor: BOCK ANDREAS
IPC: B60C17/06
Filed: 1994-01-27
Granted: 2001-01-31
Abstract: An emergency rim ring (1) made of elastic material for a vehicle wheel (8) with a one-part drop base rim (10) consists of a one-piece ring-shaped body (2) that is entirely supported on the rim base (13) of the wheel (8) via support rings (3, 4) and is set off from at least one sidewall region (22 or 23) of a pneumatic tire (9). Reinforcement patches (6) are arranged radially in such a way that they encompass relatively little compressible elastic material. This gives the emergency rim ring (1) a high torsional stability to the rim (10). Further, the emergency rim ring (1) can be easily mounted and is very stable against displacement even in cornering on tires (9) with low air pressure.
Patent EP-0876446-B2 (EP)
Inventor: WITTENBRINK ROBERT JAY
IPC: C10M107/02
Filed: 1996-11-15
Granted: 2010-10-27
Abstract: L'invention concerne de nouvelles huiles biodégradables extrêmement efficaces à base d'hydrocarbures, utiles en tant que lubrifiants dans des compositions industrielles et dans des compositions d'huiles de moteur, ainsi que le procédé servant à les préparer. On effectue la réaction d'une charge cireuse ou paraffinique, en particulier, une charge de Fischer-Tropsch, au-dessus d'un catalyseur à double fonction, de manière à produire des réactions d'hydroisomérisation et d'hydrocraquage, à des niveaux de conversion de 700 °F+ dans une plage de 20 à 50 % en poids, de préférence de 25 à 40 % en poids, afin d'obtenir une fraction brute, par exemple, une fraction brute de C5 - 1050 °F, contenant des isoparaffines de 700 °F+ possédant 6 à 7,5 ramifications de méthyle pour 100 atomes de carbone dans la molécule. On effectue la distillation primaire des paraffines méthyliques par l'intermédiaire d'une distillation atmosphérique, afin de produire une fraction de distillation possédant une point d'ébullition initial situé entre 650 °F et 750 °F, dont on extrait la cire au solvant, l'huile exempte de cire étant ensuite fractionnée sous vide poussé, de manière à obtenir des huiles de base hydrocarbonées biodégradables présentant une efficacité élevée.
Patent EP-1019446-B2 (EP)
Inventor: HARRIS J MILTON
IPC: A61K47/10
Filed: 1998-01-23
Granted: 2011-11-30
Abstract: This invention relates to hydrolytically degradable gels of crosslinked poly(ethylene) glycol (PEG) structures. Addition of water causes these crosslinked structures to swell and become hydrogels. The hydrogels can be prepared by reacting two different PEG derivatives containing functional moieties at the chain ends that react with each other to form new covalent linkages between polymer chains. The PEG derivatives are chosen to provide covalent linkages within the crosslinked structure that are hydrolytically degradable. Hydrolytic degradation can provide for dissolution of the gel components and for controlled release of trapped molecules, including drugs. Reagents other than PEG can be avoided. The hydrolysis rates can be controlled by varying atoms adjacent to the hydrolytically degradable functional groups to provide substantially precise control for drug delivery in vivo.
Patent JP-H0442-B2 (JP)
IPC: A01N57/28
Filed: 1983-06-04
Abstract: N min -(Methoxy)methylthio)phosphinyl)-N,N-dimethylcarbamimidothioic acid, ethyl ester is employed as an insecticide and particularly plant systemic insecticides for the control of sucking and boring-type insects which attack plants of economic importance.
Patent JP-H0455710-B2 (JP)
IPC: A01N37/16
Filed: 1990-04-24
Abstract: Medical instruments, which may include brass, copper, aluminum, stainless steel, carbon steel, or plastic parts are microbially decontaminated (sterilized or disinfected) in an antimicrobial solution. To provide a long shelf life, premeasured doses of powdered reagents are sealed in an ampule until ready for use. The powdered reagents are selected such that they react in the presence of water to form a strong oxidant solution in an appropriate concentration to be effective as an antimicrobial. The preferred powdered reagents include acetylsalicylic acid and sodium perborate which react in the presence of water to form a peracetic acid solution. Moreover, these dry reagents form sodium metaborate and salicylic acid, both corrosion inhibitors to inhibit corrosion of metal parts of the medical instruments. The ampule may also hold a preselected dose of phosphate or other water soluble corrosion inhibitors and a wetting agent.
Patent JP-H0548514-B2 (JP)
Inventor: HAGHIRI-TEHRANI YAHYA
IPC: B42D15/10
Filed: 1985-05-28
Abstract: The integrated circuit embedded in a data carrier and the contact surfaces connected with this circuit are to be protected against bending of the data carrier. For this purpose, the data carrier is divided into two areas, the first one, which bears the circuit and is generally small compared to the second area, being connected to the second area via a predetermined breaking point. Stress which occurs when the data carrier is bent is kept away from the circuit, or transmitted only weakly to it, by the predetermined breaking point.
Patent JP-2525408-B2 (JP)
IPC: C07F9/48
Filed: 1987-05-11
Granted: 1996-08-21
Abstract: A process is provided for preparing phosphonous acids of the structure wherein R1 is lower alkyl or arylalkyl <CHEM> which are useful in preparing phosphinic and phosphonic acid ACE inhibitors, which process includes the steps of treating an olefin of the structure R1-CH=CH2 wherein R2is lower alkyl or arylalkyl with a phosphorus-containing reagent such as sodium hypophosphite or hypophosphorous acid in the presence of an organic alcohol solvent such as ethanol or methanol, and a radical initiator such as azobisisobutyronitrile, under acidic conditions, preferably at the reflux temperature of the organic solvent, to form the phosphonous acid without forming the alkyl ester.
Patent JP-2864323-B2 (JP)
IPC: C03C10/00
Filed: 1993-05-24
Granted: 1999-03-03
Abstract: An apparatus is presented for economically making crystallized glass products from waste ash produced from the sewage sludge dewatered by organic matters, which is usually regarded to be difficult to process. The melting is performed in two furnaces: the primary melting furnace and the secondary melting furnace. The primary furnace melts waste ash and the primary melt is charged into the secondary melting furnace. The glassy material produced in the secondary melting furnace is charged into a crystallization furnace to convert the glassy material to a crystallized glass product. This basic configuration of the apparatus allows the production of either irregular shaped crystallized products, such as crushed stone like products, or crystallized manufactured products, such as tiles and blocks, depending on the combination of processing equipment and their operating conditions. The apparatus enables the production of crystallized glass products from waste ash feed economically, because of the flexibility and versatility in the design of the apparatus. <IMAGE>
Patent JP-3881747-B2 (JP)
IPC: A61M60/88
Filed: 1997-05-22
Granted: 2007-02-14
Abstract: An apparatus for circulating a purge solution in an artificial organ (1) has an ultrafiltration filter (71) or reverse osmosis filter (71) in a purge solution circulation route (90, 91) to inhibit passage of substances having molecular weights of 340,000 or more. A portion of the purge solution circulated by a purge solution circulation pump (58) is passed through this filter (71) to remove proteins that have mixed in the purge solution. The purge solution free from the proteins is supplied and circulated through the artificial organ (1). Proteins that have externally mixed in the purge solution can be prevented from coagulating and depositing on a seal mechanism and the like of the artificial organ (1). <IMAGE>
Patent JP-2538137-B2 (JP)
IPC: H01R12/50
Filed: 1991-06-10
Granted: 1996-09-25
Abstract: The present invention relates to an electrical connector with a ground structure for impedance and cross talk control between signal carrying conductors such as a circuit (224) and a connector (400) having first contacts (435) and second side contacts (465). In particular, a right angle or angled connector (200) comprising an insulative housing (230) having side walls (230) and a plurality of passages in rows and columns within the side walls. The connector further comprises a first plurality of contact elements (235), each element having a third and fourth (255) contact, the third contacts arranged for contacting the first contacts (435) and the fourth contacts (255) extending at an angle to the third contacts (235). The connector further comprises a conductor (240) arranged on a side wall (230) having a fifth contacts (265) for contacting the second side contacts (465) of the second connector (400) and a sixth contacts (275) for contacting a conductive shield (300), the shield having contacts (315) positioned in rows and columns with the fourth contacts (255) for connection to the circuit (224). <IMAGE>
Patent JP-3098323-B2 (JP)
IPC: E04B9/30
Filed: 1992-06-01
Granted: 2000-10-16
Abstract: A support system for trimming exposed edges of suspension ceilings provides a trim strip mounting clip which mounts on the bulb of an adjacent grid tee member and provides a face portion which snaps into and locks with a channel-shaped trim strip. The connector clip supports the trim strip from the adjacent grid members without any exposed fasteners and provides an uninterrupted finished edge appearance. Several embodiments of connector clips are illustrated, one of which provides a support portion pivotally connected to a face portion so that trim strips can be mounted on adjacent grid members in positions parallel to the adjacent grid members and at angles relative thereto. Also disclosed are splice plates which bridge between abutting ends of trim strips to lock such abutting ends in proper alignment. Such splice plates can be used with straight or curved trim strips and can also be used at inside corners.
Patent JP-H0458191-B2 (JP)
IPC: H01L21/28
Filed: 1982-08-17
Abstract: Complementary MOS field effect transistor circuits are produced in silicon gate technology, with the method steps up to the structuring of the gate electrode being executed in a known manner. Both source/drain implantations (FIG. 3, 8 and FIG. 5, 10) occur with only one mask (7a). This mask (7a), which is composed of silicon nitride, is utilized for the source/drain implantation 8 of the n-channel transistors (9). The source/drain implantation (10) for the p-channel transistors (11) occurs without a mask and the oxide layer thickness, d6, over the source/drain regions of the n-channel transistors (9) functions as a masking layer. An advantage of this process sequence is that switched capacitor structures (FIG. 6, 5b, 12) can be simultaneously produced whereby the oxide layer thickness, d4, over the polysilicon-1 level (5a, 5b) determines the thickness of the insulating layer, dcox, of the capacitor structures (5b, 12). This technique is useful for manufacturing VLSI CMOS circuits in VLSI technology with and without switched capacitors.
Patent JP-2604133-B2 (JP)
IPC: F16K31/122
Filed: 1985-07-02
Granted: 1997-04-30
Abstract: A pneumatically operated reciprocating three-way valve having particular application to a double diaphragm pump is operative without a lubricating oil mist or the inefficiency resulting from air leakage between the valve piston (72) and cylinder (74). Sticking and stalling of the valve piston are prevented by deformation of the cylinder (74) under pressure to provide leakage of selected cavities within the valve. The pump also avoids the use of a deicer mist by an adjustable bleed of high pressure air to provide a two-step exhaust
Patent JP-3107646-B2 (JP)
IPC: F04C2/10
Filed: 1992-06-05
Granted: 2000-11-13
Abstract: The invention relates to a lubrication gear pump for an internal combustion engine, especially for motorised vehicles, having a pump casing attached to the engine and also having an external rotor which is arranged in the pump casing, in addition an internal rotor being arranged inside the external rotor or inside the pump casing, and at least one suction duct and/or at least one discharge duct being provided in the pump casing, and a drive also being provided, according to the invention the pump being integrated in a pinion or a pulley of the combustion engine, and the external rotor or external rotors being driven by the pinion or the pulley. <IMAGE>
Patent JP-H0233353-B2 (JP)
IPC: C12N1/20
Filed: 1981-10-07
Abstract: 1. Aqueous nutrient medium for the cultivation of microorganisms, characterised in that a component of the medium is a carbohydrate-free protein hydrolysate solution containing 0.2 to 5.0% cystein, which is prepared by hydrolysing horn, feathers or hair with mineral acid, and neutralising and filtering the hydrolysate.
Patent JP-S622326-B2 (JP)
IPC: G06F3/16
Filed: 1979-12-14
Abstract: PURPOSE:To obtain an output sentence having an excellent natural properties of the reproduced sound, by connecting a memory interface to each of plural processors via an independent system respectively and thus eliminating the delay of response to an output request. CONSTITUTION:The data obtained by giving a digital coding to the aural wave is stored in the memory VM and then read out selectively to be reproduced into the voice after a conversion into the analog quantity. Such device consists of the processor CPU1 and CPU2 of several units for editing of a sentence in accordance with the external signal SI; the memory interface MI which is connected to each of the above processors and then delivers the address of the aural data to be reproduced to the memroy VM; the output device OUT which converts the aural data into the analog quantity; and others. Then those plural CPUs are connected to the MI via the system bus SB which is independent with every CPU, and the MI is connected to the VM via the common memory bus MB respectively.
Patent JP-2848676-B2 (JP)
IPC: F16L5/02
Filed: 1990-06-25
Granted: 1999-01-20
Abstract: A bushing (27) for the sealing passage of a cable, pipe and the like through a wall, comprising a frame (1) made of a rigid material which may be sealingly inserted in an aperture provided in the wall, as well as one or more parallelepipedal blocks (20) of a resilient material which may be composed from two identical halves, which blocks (20) in their composite state exhibit a bore adapted to the shape and dimensions of a cable to be passed through, which blocks (20) can be inserted in the frame aperture so as to be a fine fit, with the two halves of every block encasing a cable, whereby the blocks are dimensioned such that, under operating conditions of the bushing (27), the extend outwards on at least one side of the frame (1) in a direction transverse to the plane of the frame, which blocks (20) are provided with circumferential internal ribs (22) over at least a part of their length, and whereby blocks (20) whose outer faces rest against an inner wall of the frame under operating conditions of the bushing are provided with external ribs (23) over at least a part of the said outer faces.
Patent JP-4159183-B2 (JP)
IPC: F04B37/20
Filed: 1999-06-17
Granted: 2008-10-01
Abstract: A gas ballast system for multistage vacuum pumps, e.g. for piston pumps and membrane pumps, has flow restrictions (10) to bleed gas into the connecting duct (5) between the pump stages and with another flow restriction (10') to bleed gas into the displacement chamber (8) of the first stage. The control of the gas ballast uses simple components and is simple to adjust.
Patent JP-2909021-B2 (JP)
IPC: A61F2/84
Filed: 1996-07-01
Granted: 1999-06-23
Abstract: This is an implantable vaso-occlusive device. It is typically a vaso-occlusive coil comprised of a primary helically wound coil which may then be wound into a secondary shape. Central to the invention is the use of a stretch-resisting member fixedly attached within at least a portion of the primary coil. The stretch-resisting member may be formed into coil tips at the ends of the coil by melting the polymeric fibers or alloys or by attaching the fibers with a glue. This stretch-resisting member is for the primary purpose of preventing stretching of the coil during movement of that coil, e.g., by retrieval or repositioning after deployment. The device typically has a self-forming secondary shape made from a pre-formed primary linear helically wound coil, although it need not have the secondary form. External fibers may be attached to the device and affixed to the pre-formed linear member to increase. The vaso-occlusive member may be also be covered with a fibrous braid. The device is typically introduced into the body through a catheter. The device is passed axially through the catheter sheath and assumes its secondary form upon exiting the catheter. <IMAGE>
Patent JP-H0244823-B2 (JP)
IPC: C07C45/50
Filed: 1985-08-27
Abstract: A method for the production of aldehydes from olefins with CO/H2 in the presence of a water-soluble rhodium-containing catalyst system is described. The reaction proceeds at 0.1 to 10 MPa and 20 to 160 DEG C. Ultrasound acts on the reaction mixture, consisting of an aqueous catalyst, an olefin, synthesis gas and the end products.
Patent JP-3466058-B2 (JP)
IPC: H04N19/463
Filed: 1997-07-30
Granted: 2003-11-10
Abstract: PROBLEM TO BE SOLVED: To provide an image encoding device, an image decoding device, an image encoding method, and an image decoding method which can perform encoding and decoding more efficiently than when conventional binary image encoding and decoding technologies are used by predicting encoded pixels from a previously obtained binary image having high correlation and encoding their differences, and providing a medium in which programs for making a compute execute those operations are recorded. SOLUTION: This device is provided with a block dividing means 1(101) which inputs an object binary image to be encoded and divides the object binary image into blocks containing pixels to obtain an object block, a block dividing means 2(102) which divides the previously obtained reference binary image into blocks containing pixels to obtain a reference block, an exclusive OR block constituting means (103) which scans the said object block and reference block in order to detect exclusive OR between both pixel values and constitute an exclusive OR block, and an exclusive OR encoding means (104) which generates a code sequence of the exclusive OR and outputs it as encoded data.