baber/WOPTO huggingface dataset:
Patent DE-69530508-T2 (DE)
Inventor: MILLER D
IPC: G01T1/11
Filed: 1995-06-02
Granted: 2003-12-24
Abstract: The present invention is a composite material containing a mix of dosimeter material powder and a polymer powder wherein the polymer is transparent to the photon emission of the dosimeter material powder. By mixing dosimeter material powder with polymer powder, less dosimeter material is needed compared to a monolithic dosimeter material chip. Interrogation is done with excitation by visible light.
Patent DE-69532412-T2 (DE)
Inventor: CORBIER ALAIN
IPC: C07D233/84
Filed: 1995-02-27
Granted: 2004-10-07
Abstract: Use of tetra-substd. imidazole derivs. of formula (I), their enantiomers and diastereomers and their acid and base addn. salts, to treat disorders arising from abnormal stimulation of angiotensin II receptors AT1 and AT2, is new. R1 = 1-6C alkyl, alkylthio, alkoxy, aryl, arylthio, aryloxy or aryl(1-6C)alkyl; R2 = -S-R, -O-R, -C(OH)(R)-COOH; halo; or -C(=O)Z; R = 1-8C alkyl, 2-8C alkenyl, 3-6C cycloalkyl or aryl (all opt. substd.); Z = OH, alkoxy or carboxy; R3 = carboxy, acyl halo, 1-8C alkyl, 2-8C alkenyl or alkylthio, aryl, aryl(1-6C)alkyl or aryl(2-6C)alkenyl; R4 = -(CH2)ml-COOR14, -(CH2)ml-CONHR14, -(CH2)ml-CN, -SO2-NH-SO2-R14, -NH-SO2-R14, -PO3R14, SO2NHSO2NR14R15, -SO2NHSO2N(-CH2-CH2-)2D, -SO2-W-R14, etc.; m1 = 0-4; D = O or S; W = -NR15-, -NH-CO-, -NH-CO-O-, -N=CH-N-R15-, or -NH-CO-NR15-; R14, R15 = H, 1-8C alkyl, 2-8C alkenyl, 3-6C cycloalkyl or aryl; or NR14R15 = pyrrolyl, pyrrolinyl, pyrrolidinyl, piperazinyl, alkylpiperazinyl, phenylpiperazinyl, morpholinyl or indolinyl; alkyl radicals are opt. interrupted by one or more heteroatoms (O, N or S); S atoms are opt. oxidised to sulphone or sulphoxide.
Patent DE-69604589-T2 (DE)
Inventor: WILMSEN MARCO
IPC: F16F1/42
Filed: 1996-07-12
Granted: 2000-05-18
Abstract: PCT No. PCT/NL96/00286 Sec. 371 Date Feb. 18, 1998 Sec. 102(e) Date Feb. 18, 1998 PCT Filed Jul. 12, 1996 PCT Pub. No. WO97/04246 PCT Pub. Date Feb. 6, 1997The invention relates to a vibration damper having a housing formed by a shell part (1) and a base part (2), in which housing a pressure cavity (3) is located, which cavity at least partially is delimited by a membrane (4) of elastomer material. A pin (5) for transmitting vibrations to the membrane is fixed to the membrane and protrudes through the housing to the outside. The pin is fixed to the membrane by means of a plate (10) enclosed within the membrane, which plate (10) is dome-shaped and can be made of resilient material, such as spring steel. The membrane is attached to the shell part (1) by means of a type of adhesive joint at the location of the transition between the base (8) of the shell part and the side wall (9) of the shell part. The plate enclosed within the membrane can act as a leaf spring.
Patent DE-69609324-T2 (DE)
Inventor: LUND AGNER
IPC: F01N3/02
Filed: 1996-04-11
Granted: 2001-03-15
Abstract: A combined heat exchanger and silencer apparatus is used for recovering heat from hot combustion gas exhausted from a combustion engine and for reducing the noise of the exhausted gas. The apparatus defines a first passage (12) for combustion gas and a second passage (30) for a heat receiving medium, such as water, being in heat conductive contact with the combustion gas in the first passage. The first passage (12) comprises a plurality of substantially co-extending passage sections (15, 16, 20; 40, 41, 45). Plenum chambers (17, 18, 19, 42) are arranged at opposite ends of the passage sections for interconnecting adjacent ends thereof, and at least one of the first passage sections, which interconnects opposite plenum chambers, contains silencer means (21-23; 25, 26) so as to function as a silencer. The apparatus may also contain at least one bypass passage so that the flow of combustion gas may bypass at least some of the heat exchanging passage sections, but pass through the passage sections containing the silencer means.
Patent DE-69613244-T2 (DE)
Inventor: LEVI SHEM-TOV
IPC: H01Q5/42
Filed: 1996-07-04
Granted: 2002-04-25
Abstract: The antenna comprises two planar array layered antenna units, one operating in a low frequency band, the other operating in a high frequency band. The first antenna is the top unit and the second antenna is the bottom unit. The first unit has dielectric plates with front and rear faces, planar patch areas filled with conducting material on the face of a dielectric plate array, and a feed array, each having a feed connected to one of the array patches. Each patch resonates at the low frequencies and is transparent to the high frequencies, while a ground plane reflects low frequencies and is transparent to high frequencies. The second antenna is similarly constructed.
Patent DE-69616341-T2 (DE)
Inventor: CAMPBELL M
IPC: B44B5/00
Filed: 1996-06-12
Granted: 2002-06-27
Abstract: The present invention provides an apparatus and method of embossing a sheet of material with a background pattern together with additional selectable indicia, wherein the method comprises the steps of removably securing an indicia-bearing element to a first one of embossing rollers and removably securing a yieldable element to a second one of embossing rollers, passing the sheet material through the nip of rigid embossing rollers while synchronously moving the embossing rollers so as to impart a background, embossed pattern to a first portion of the sheet material and secondly imparting additional indicia to second portions of the sheet material by repetitively bringing into opposing relationship at the nip the indicia-bearing element and the yieldable element.
Patent DE-69626010-T2 (DE)
Inventor: ISLAM KHALID
IPC: A61K31/19
Filed: 1996-05-20
Granted: 2003-07-24
Abstract: The present invention concerns the use of puberulic or puberulonic acid as inhibitors of the enzyme iositol monophosphatase (EC 3.1.3.25) and thus useful in the treatment of manic or depressive symptoms.
Patent DE-69633557-T2 (DE)
Inventor: FREI JOERG
IPC: A61P43/00
Filed: 1996-01-15
Granted: 2005-10-13
Abstract: PCT No. PCT/EP96/00143 Sec. 371 Date Jul. 23, 1997 Sec. 102(e) Date Jul. 23, 1997 PCT Filed Jan. 15, 1996 PCT Pub. No. WO96/22979 PCT Pub. Date Aug. 1, 1996Described are compounds of formula I    <IMAGE>  (I)  wherein R1 is hydrogen or hydroxy; R2, R2' and R2'' are each independently of the others hydrogen or a substituent other than hydrogen; either R3 is hydrogen or a substituent other than hydrogen and R4 is hydrogen or lower alkyl, or R3 and R4 together form a divalent radical of the formula -(CH2)n- wherein n is 2 or 3; R5 and R6 are each independently of the other hydrogen, alkyl or aryl; and either R7 and R8 are each hydrogen, or R7 and R8 together form a bond; tautomers thereof, provided that at least one tautomerisable group is present; and salts thereof. The compounds inhibit the enzyme S-adenosylmethionine decarboxylase and are suitable, for example, for the treatment of tumours and protozoal infections.
Patent DE-69633973-T2 (DE)
Inventor: KOIKE MASAMICHI
IPC: C07K16/28
Filed: 1996-09-11
Granted: 2005-12-22
Abstract: The present invention provides monoclonal antibodies and humanized antibodies which react specifically with a human interleukin-5 receptor  alpha  chain. The invention also provides hybridomas and transformants which produce the antibodies, the monoclonal antibodies and humanized antibodies, a method for detecting an interleukin-5 receptor  alpha  chain immunologically by means of these antibodies, as well as a method for diagnosing and treating diseases such as chronic bronchial asthma by means of the monoclonal antibodies and humanized antibodies. The present invention is useful for diagnosis or treatment of diseases such as chronic bronchial asthma.
Patent DE-69634056-T2 (DE)
Inventor: GREFF RICHARD J
IPC: A61K31/745
Filed: 1996-07-29
Granted: 2005-12-08
Abstract: Disclosed are novel compositions for embolizing blood vessels which are particularly suited for treating vascular lesions via catheter delivery. In one embodiment, the compositions of this invention comprise a biocompatible polymer, a biocompatible solvent and a biocompatible water insoluble contrast agent characterized by having an average particle size of less than about 10  mu m. In another embodiment, the biocompatible polymer in these compositions is replaced with a biocompatible prepolymer.
Patent DE-69712063-T2 (DE)
Inventor: SANTINI JOHN T
IPC: A61K9/52
Filed: 1997-07-02
Granted: 2002-10-24
Abstract: Fabrication methods are provided for microchips that control both the rate and time of release of multiple chemical substances and allow for the release of a wide variety of molecules in either a continuous or pulsatile manner. In all of the preferred embodiments, a material that is impermeable to the drugs or other molecules to be delivered and the surrounding fluids is used as the substrate. Reservoirs are etched into the substrate using either chemical (wet) etching or plasma (dry) etching techniques well known in the field of microfabrication. Hundreds to thousands of reservoirs can be fabricated on a single microchip using these techniques. A release system, which includes the molecules to be delivered, is inserted into the reservoirs by injection, inkjet printing, or spin coating methods. Exemplary release systems include polymers and polymeric matrices, non-polymeric matrices, and other excipients or diluents. The physical properties of the release system control the rate of release of the molecules. The reservoirs can contain multiple drugs or other molecules in variable dosages. The filled reservoirs can be capped with materials that passively disintegrate, materials that allow the molecules to diffuse passively out of the reservoir over time, or materials that disintegrate upon application of an electric potential. Release from an active device can be controlled by a preprogrammed microprocessor, remote control, or by biosensors.
Patent DE-69713157-T2 (DE)
Inventor: KAMSTRA REIN
IPC: B65B55/10
Filed: 1997-07-04
Granted: 2003-01-30
Abstract: Sterilization device intended to sterilize objects, such as bottles, comprising feed and discharge means for objects, a rotatable treatment unit, which in the region of its circumference comprises treatment cavities, each treatment cavity comprising an opening for feeding and discharging the objects, which opening can be closed and opened with the aid of closure means in the form of an endless belt which bears against the treatment unit over at least a part of its circumference, and it being possible to connect the treatment cavities to a feed for process media. A description is also given of a method for sterilizing objects using the device.
Patent DE-69714758-T2 (DE)
Inventor: SHIH NENG-YANG
IPC: A61P11/06
Filed: 1997-10-30
Granted: 2003-01-02
Abstract: Compound represented by structural formula (I) or a pharmaceutically acceptable salt thereof, wherein: a is 0, 1, 2 or 3; b, d and e are independently 0, 1 or 2; R is H, C>1-6< alkyl, -OH or C>2<-C>6< hydroxyalkyl; A is an optionally substituted oxime, hydrazone or olefin; X is a bond, -C(O)-, -O-, -NR?6>-, -S(O)e-, -N(R<6>)C(O)-, -C(O)N(R<6>)-, -OC(O)NR<6>-, -OC(=S)NR<6>-, -N(R<6>)C(=S)O-, -C(=NOR<1>)-, -S(O)2N(R<6>)-, -N(R<6>)S(O)2-, -N(R<6>)C(O)O- or -OC(O)-; T is H, phthalimidyl, aryl, heterocycloalkyl, heteroaryl, cycloalkyl or bridged cycloalkyl; Q is -SR<6>, -N(R<6>)(R<7>), -OR<6>, phenyl, naphthyl or heteroaryl; R<6a>, R<7a>, R<8a>, R<9a>, R<6> and R<7> are H, C1-6 alkyl, C2-C6 hydroxyalkyl, C1-C6 alkoxy-C1-C6 alkyl, phenyl or benzyl; or R<6> and R<7>, together with the nitrogen to which they are attached, form a ring; R<9a> is R<6> or -OR<6>; and Z is spiro-substituted piperidinyl or substituted piperazinyl wherein aryl, heterocycloalkyl, heteroaryl, cycloalkyl and bridged cycloalkyl groups are optionally substituted; methods of treating asthma, cough, bronchospasm, inflammatory diseases, and gastrointestinal disorders with said compounds, and pharmaceutical compositions comprising said compounds are disclosed.
Patent DE-69717827-T2 (DE)
Inventor: ULRICH WOLF-RUEDIGER
IPC: C07D405/14
Filed: 1997-08-13
Granted: 2003-09-04
Abstract: Compounds of formula Iwherein R1 is 1-2C-alkoxy optionally substituted by flourine, R2 is methyl, 1-methylethyl, 3-7C-cycloalkyl or 3-7Ccycloalkylmethyl and Ar is a pyridyl which is optionally di-halo substituted.
Patent DE-69727816-T2 (DE)
Inventor: BEATY D
IPC: A61B17/16
Filed: 1997-07-17
Granted: 2004-08-05
Abstract: The invention set forth includes a set of tools which compact bone tissue as they develop a bore in the bone tissue and a driving mechanism for providing movement to the tools. The tools have engaging surfaces which displace bone tissue radially outward with respect to a central axis of the tool to create high density bone tissue at the wall defining the bore. The driving mechanism may provide only vibrational movement to assist in inserting the tool. Alternatively, the driving mechanism may provide translational movement in the longitudinal direction with respect to the tool to insert the tool into the bone.
Patent DE-69729799-T2 (DE)
Inventor: STUDER DANIEL
IPC: G01N1/06
Filed: 1997-12-19
Granted: 2004-12-02
Abstract: The device comprises a holder (19) and a block (18) attached to the holder (19) by one or two leaf springs (20) which are perpendicular to the cutting edge (2) of a diamond blade (1) attached to the block (18). A vibrator (30) cooperates with the block (18) to vibrate it parallel to the cutting edge (2). Thereby, the effective sectioning angle of the blade (1) is significantly reduced which eliminates or at least strongly reduces compression of the cut sections. <IMAGE>
Patent DE-69730446-T2 (DE)
Inventor: BOWER S
IPC: A23K1/165
Filed: 1997-12-16
Granted: 2005-09-15
Abstract: The present invention relates to a modified cellulase protein which is advantageously used in the treatment of textiles. Particularly, a method for treating a cellulose containing fabric is provided comprising the steps of forming an aqueous solution comprising a cellulase composition which differs from a precursor cellulase in that it has been enlarged and contacting the aqueous solution with a cellulose containing fabric for a time and under conditions appropriate to treat the fabric. The enlarged cellulase may comprise a multimeric composition of two or more distinct cellulase units or a single cellulase which has had adhered thereto polymeric or fibrous constituents.
Patent DE-69732327-T2 (DE)
Inventor: OZAKI AKIO
IPC: C12N15/09
Filed: 1997-09-03
Granted: 2005-10-06
Abstract: Provided is an industrially applicable process for producing trans-4-hydroxy-L-proline, which is useful as a raw material for medicines or as an additive to foods. In the process, L-proline is converted into trans-4-hydroxy-L-proline in the presence of an enzyme source which is derived from a microorganism belonging to the genus Dactylosporangium, Amycolatopsis or Streptomyces and which catalyzes the hydroxylation of L-proline into trans-4-hydroxy-L-proline, a divalent iron ion and 2-ketoglutaric acid, in an aqueous medium, and the produced trans-4-hydroxy-L-proline is collected from the aqueous medium. Also provided is a novel transformant containing a gene, coding for L-proline-4-hydroxylase and having a reinforced L-proline biosynthesis activity. In addition, provided is a process for producing L-proline-4-hydroxylase using the transformant which contains the gene and has a reinforced proline biosynthesis activity.
Patent DE-69732655-T2 (DE)
Inventor: LIN DONNA
IPC: A61M29/02
Filed: 1997-09-10
Granted: 2006-05-04
Abstract: An inflatable medical device for delivering fluid internally to a patient comprising a catheter having a fluid delivery lumen communicating between a fluid entry port at its proximal end and a fluid delivery port on an external wall of the catheter and a hollow, inflatable balloon having at least one fluid transmitting conduit disposed between inner and outer balloon walls. The fluid transmitting conduit receives fluid from the fluid delivery port of the catheter and is connected to at least one outlet on the outer balloon wall. The inner balloon wall extends axially beyond the proximal terminus of the outer balloon wall to form an inner sleeve for attaching the inner balloon wall to the catheter. An outer collar is attached at its distal end to the outer balloon wall and at its proximal end to the catheter at a point proximal to the fluid delivery port. The outer collar forms a conduit between the fluid delivery port and the proximal opening of the fluid transmitting conduit of the balloon. The diameter of the outer collar decreases gradually, or in at least one discrete step, from an enlarged area to a proximal catheter attachment area.
Patent DE-69733626-T2 (DE)
Inventor: TOYODA YUKIO
IPC: C07K16/44
Filed: 1997-10-01
Granted: 2006-05-11
Abstract: A hybridoma obtainable by fusing a spleen cell or lymphocyte of an animal immunized by a complex of a surfactant compound for synthetic detergent and protein with a myeloma cell, which produces a monoclonal antibody against the compound or its degradation product. A monoclonal antibody against a surfactant compound for synthetic detergent or its degradation product which is produced by the hybridoma, a kit for immunoassay of detergent, its degradation product or a mixture thereof containing as an essential constitutional component the monoclonal antibody, and an immunoassay method, in particular, ELISA of detergent, its degradation product or a mixture thereof in a specimen by reacting the specimen with the monoclonal antibody supported on a carrier and the detergent, its degradation product or the mixture thereof labeled with a labeling agent are also disclosed.
Patent DE-69808474-T2 (DE)
Inventor: FERRIS ROBERT
IPC: H04N5/445
Filed: 1998-07-20
Granted: 2003-07-10
Abstract: A remote control device for consumer broadcast receivers, particularly television and radio receivers, is disclosed. In addition to the remote control features normally found on such a device, the device also contains a display on which advertisements, product and service offers, and other information (collectively, "display data") may be shown to the user. The device receives such display data via a radio link from one of a plurality of central processing stations. The user of the device may interact with such display data (for example, to purchase an advertised good), and the device may send back details of such interactions to a central processing station, which in turn may initiate a transaction with the appropriate sponsoring party.
Patent DE-69813013-T2 (DE)
Inventor: BJUR KENT
IPC: D01F2/08
Filed: 1998-10-21
Granted: 2003-09-25
Abstract: The present invention relates to a method of reducing the clogging of nozzles and slits and diminishing the formation of deposits in the spin bath system in the process of making viscose filamentary and film materials by using an alkoxylated polyamine surfactant having the formula:where R represents a hydrogen or an aliphatic group with 1-24 carbon atoms, each A represents a hydrogen, an aliphatic group with 1-24 carbon atoms, or H(OCmH2m)y-groups, where m is a number from 2-3, n is a number from 2-3, x is 4-8, with the proviso that the number of H(OCmH2m)y-groups are from 1 to x+1, and the total number of carbon atoms in the aliphatic groups is from 8 to 45. The alkoxylated polyamine surfactant has an excellent anticlogging effect, since it is a good dispersant and prevent or reduce precipitation in the spin bath. In addition it is very stable.
Patent DE-69814148-T2 (DE)
Inventor: BJORCK HENRIK
IPC: C12N5/10
Filed: 1998-11-11
Granted: 2004-03-18
Abstract: A nuclear delivery construct comprises (i) protein H or a fragment or derivative thereof that is capable of being targeted to the nucleus of a eukaryotic cell; and associated therewith (ii) one or more other components whose targeting to the nucleus of the eukaryotic cell is desired.
Patent DE-69819707-T2 (DE)
Inventor: WAGNER ARMAND
IPC: B65D43/02
Filed: 1998-08-11
Granted: 2004-09-30
Abstract: A pilferproof or tamper resistant cover or lid (10) for a container (C) comprising a skirt (14) having on its inner surface a circumferential nose (20) for engaging a flange (50) at an upper end of the container (C) and a tear-off safety band (30) having an inwardly inclined generally half tear-shaped cross-sectional form adapted to be snugly received in a groove (54) of the container (C) below the flange (50) thereof. <IMAGE>
Patent DE-69819789-T2 (DE)
Inventor: OH KWANG
IPC: C12N1/21
Filed: 1998-03-21
Granted: 2004-09-30
Abstract: This invention relates to a strain of E.coli JM83/pKP2 transformed by a plasmid and phytase produced therefrom, and more particularly, to the strain E.coli JM83/pKP2 transformed with a recombinant vector pKP1 or pKP2, so prepared by gene manipulation.
Patent DE-69822561-T2 (DE)
Inventor: GUIDOT DOMINIQUE
IPC: G06F9/46
Filed: 1998-06-15
Granted: 2005-02-24
Abstract: The procedure for isolating in a divided computer memory a point containing an obsolete value for a variable, in which the point is referenced by a pointer for access within the frame of a first transaction (T1) and a hold preventing access to the point for all but one task, consists of deleting in the descriptor of the variable the identity (T1) of the aborted transaction and the address (ADR1) of the point and writing the address in the descriptor of the transaction before releasing the hold. If the first transaction is aborted because of a second transaction which demands access to the variable to write a new value (Vnou) and which validates the access, and where the obsolete value precedes the current value (Vcou), the procedure consists of changing the address of the points containing the current obsolete and new values in the descriptor of the variable.
Patent DE-69834039-T2 (DE)
Inventor: WINSTON R
IPC: A61B18/24
Filed: 1998-07-08
Granted: 2006-08-31
Abstract: Guidance systems for guiding a catheter through tissue within a body are described. In one form, the system is implemented in connection with a catheter which includes a catheter body having a optic fibers extending between a first end and a second end thereof. The guidance system is coupled to the catheter body and includes a first optic fiber, a second optic fiber, and a detecting element. The first optic fiber includes a first end and a second end, and is coupled to the catheter body so that the first optic fiber second end is adjacent the catheter second end. The second optic fiber also includes a first end and a second end, and a reference mirror is positioned adjacent the second optic fiber second end. The first optic fiber first end is communicatively coupled to the detecting element and the second optic fiber first end is communicatively coupled to the detecting element. The detecting element is configured to determine interference between a light beam propagating through the first optic fiber and a light beam propagating through the second optic fiber.
Patent DE-69837219-T2 (DE)
Inventor: GEREMIA RENATO
IPC: C07D487/08
Filed: 1998-12-21
Granted: 2007-07-05
Abstract: 1,4,7,10-tetraazacyclododecane-1,4-diacetic acid of formula (I):as well as its chelated complex salts with bi-valent metal ions having atomic numbers from 20 to 31, 39, 42, 43, 44, 49, or from 57 to 83, as well as their salts with anions of physiologically acceptable organic acid selected from acetate, succinate, citrate, fumarate, maleate, oxalate, or with anions of inorganic acids selected from halo acids ions. The compounds are intermediates for preparing 1,4,7,10-tetraaza-cyclododecane chelating agents.
Patent DE-69900833-T2 (DE)
Inventor: RICCI PATRIZIO
IPC: C11D17/06
Filed: 1999-07-07
Granted: 2002-10-31
Abstract: A multi-phase detergent tablet comprising:   a) a first phase in the form of a shaped body having at least one mould therein; and b) a second phase in the form of a compressed body adhesively contained within said mould, and wherein the second phase comprises an enzyme. The multi-phase tablets provide improved dissolution and cleaning characteristics together with excellent tablet integrity and strength.