baber/WOPTO huggingface dataset:
Patent NZ-501652-A (NZ)
Title: Tablet comprising a core and sugar overcoat comprising rapamycin, sugars and binders
Inventor: NAGI ARWINDER SINGH
IPC: A61P31/00
Filed: 1998-06-11
Abstract: An oral tablet dosage form of rapamycin comprising a core which is over-coated with rapamycin, and a sugar coat containing one or more sugars and one or more binders. One preferred embodiment describes a dosage tablet containing 0.05-20 mg rapamycin, sucrose in the range from 50-99% weight of the overcoat and one or more binders in a range from 0.1-10% weight of the sugar overcoat.
Patent NZ-504337-A (NZ)
Title: Catalytic oxidation of hydroxymethyl imidazoles to produce formylimidazoles
Inventor: BESSARD YVES
IPC: C07D233/64
Filed: 1998-11-10
Abstract: A process for the catalytic conversion of hydroxymethyl imidazoles to formylimidazoles is described.  The reaction takes place in the presence of a peroxide.  Formylimidazoles are important intermediate products for pharmaceutical substances.
Patent NZ-507586-A (NZ)
Title: Monitoring system
Inventor: GORDON DAVID HYMAN
IPC: H04W4/90
Filed: 1999-03-17
Abstract: A remote monitoring system comprising a signal emitter (10) providing a signal, means for detecting the signal (12), means for transmitting the signal (16) via a global specification for mobile telephones (GSM) network, and remote means (18, 20) for receiving the transmitted signal.
Patent NZ-508815-A (NZ)
Title: Pyrrole substituted 2-indolinone protein kinase inhibitors
Inventor: TANG PENG CHO
IPC: A61P17/06
Filed: 1999-05-28
Abstract: Disclosed are pyrrole substituted 2-indolineone compounds of formula (I), wherein: R1, R2 and R7 are hydrogen; R3, R4, R5 and R6 are independently selected from the group consisting of hydrogen, hydroxy, halo, unsubstituted lower alkyl, lower alkyl substituted with a carboxylic acid, unsubstituted lower alkoxy, carboxylic acid, unsubstituted aryl, aryl substituted with one or more unsubstituted lower alkyl alkoxy; and morpholino; R8 is unsubstituted lower alkyl, R9 is -(CH2)(CH2)C(=O)OH and R10 is unsubstituted lower alkyl. The compounds are used in the manufacture of medicaments for treating protein kinase related disorders.
Patent NZ-509203-A (NZ)
Title: 4-[2-[[2-hydroxy-2-(4-hydroxyphenyl)-1- methylethyl]amino]ethyl]phenoxyacetic acid derivatives having beta 3 adrenergic stimulating effect
Inventor: MUKAIYAMA HARUNOBU
IPC: C07C255/59
Filed: 1999-07-05
Abstract: A   phenoxyacetic  acid   of   formula   (I)   or   a pharmaceutically acceptable salt thereof wherein: R1  is  hydroxy,  alkoxy,  aralkoxy,  amino,  alkylamino  or dialkylamino; one  of R2 and R3 is hydrogen, halogen, alkyl or alkoxy  and the other is hydrogen; R4  is halogen, alkyl, haloalkyl, hydroxy, alkoxy, aralkoxy, cyano,  nitro,  amino, alkylamino, dialkylamino,  carbamoyl, alkylcarbamoyl, dialkylcarbamoyl or -NHCOR5; R5 is hydrogen or alkyl and the  carbon  atom  marked with (R) is a  carbon  atom  in  R configuration;  and the carbon atom marked  with  (S)  is  a carbon atom in S configuration. The compounds are useful for treating or preventing obesity, hyperglycemia,  diseases caused by intestinal hypermotility, pollakiura,  urinary  incontinence,  depression  or  disease caused  by  biliary  calculi  or  hypermotility  of  biliary tract.
Patent NZ-509406-A (NZ)
Title: In-vitro method for detecting and diagnosing acute coronary syndromes
Inventor: FREI ULRICH
IPC: G01N33/82
Filed: 1999-08-11
Abstract: An in vitro method of recognizing and diagnosing acute coronary syndromes, characterized by determining the content of choline, choline and/or trimethyl ammonium derivatives selected from the group comprising phosphoryl choline, plasmalogens and lysoplasmenyl choline in body fluids or component parts of the body.
Patent NZ-509696-A (NZ)
Title: Systems and methods for placing materials into bone
Inventor: SCRIBNER ROBERT M
IPC: A61B17/88
Filed: 1999-07-26
Abstract: Systems and methods for delivering material into bone deploy a cannula through soft tissue to establish a subcutaneous path into bone. A material is introduced into bone through the cannula. The systems and methods advance a tamping instrument through the cannula to urge material residing in the cannula into bone. The introducing step delivers material at a pressure no greater than about 360 psi
Patent NZ-511043-A (NZ)
Title: Semiconductor laser based sensing device
Inventor: MOROZOV VALENTIN
IPC: G01C3/08
Filed: 1999-09-28
Abstract: A system for determining a distance to a target object or a displacement of a target object monitors electrical characteristics of a semiconductor laser aimed at the object. Light emitted from the laser (22) is reflected from a surface(s) of the object back into the laser (22). The amount of reflected light reaching the laser affects electrical characteristics of the laser. Because the amount of reflected light reaching the laser depends on the distance to the target object, the electrical characteristics of the semiconductor laser provide an indication of the distance to the target object. Also, a change in the electrical characteristics can be used to determine an amount of displacement of a target object. A system embodying the invention could also include an optical detector array that can be focused on a target object by monitoring electrical characteristics of one or more semiconductor lasers. A plurality of semiconductor lasers could be arranged in a two-dimensional or a three- dimensional array such that the semiconductor lasers (22a, 22b, 22c) are located at different distances from a target surface. By monitoring the electrical characteristics of the plurality of semiconductor lasers, one can determine both an amount and a direction of a displacement of a target object relative to the semiconductor laser array.
Patent NZ-514414-A (NZ)
Title: Modulators of beta-amyloid peptide aggregation comprising D-amino acids
Inventor: FINDEIS MARK A
IPC: C07K14/47
Filed: 2000-03-03
Abstract: A compound having the structure: N-methyl-(D-Leu-D-Val- D-Phe-D-Phe-D-Leu)-NH2; and its use in treating disorders associated with formyloidosis.
Patent NZ-516351-A (NZ)
Title: Loudspeaker
Inventor: HARRIS NEIL
IPC: H04R1/28
Filed: 2000-07-24
Abstract: A loudspeaker having a bending wave panel (11) and an exciter (13) mounted on the panel to excite bending wave modes in the panel.  A rear box (15) defines a cavity (17) in cooperation with the panel (11).  A resonance cavity and panel in a coupled mode resonance frequency may be controlled by providing a duct (19) coupled to the cavity to selectively reduce sound pressure at the coupled mode resonance frequency.  Damping (21) may be provided in the duct (19).
Patent NZ-518531-A (NZ)
Title: Indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
Inventor: REICH SIEGFRIED HEINZ
IPC: B22D41/56
Filed: 2001-01-18
Abstract: Indazole compounds that modulate and/or inhibit cell proliferation, such as the activity of protein kinases are disclosed. These compounds and pharmaceutical compositions containing them are capable of mediating , e.g., kinases-dependent diseases to modulate and/or inhibit unwanted cell proliferation. Therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and methods of treating cancer as well as other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds is also disclosed.
Patent NZ-519972-A (NZ)
Title: Diphenyl ether compounds that inhibit monoamine reuptake and are useful in treating or preventing sexual dysfunctions
Inventor: ANDREWS MARK DAVID
IPC: C07C237/28
Filed: 2001-03-19
Abstract: A compound of general formula (I), or pharmaceutically acceptable salts, solvates or polymorphs thereof; wherein R3 is independently CF3, OCF3, C1-4alkylthio or C1-4alkoxy; n is 1, 2 or 3; and the other variables are as defined in the claims. These compounds inhibit monoamine re-uptake and in particular exhibit activity as selective serotonin re-uptake inhibitors, and are suitable for treating or preventing disorders such as depression, attention deficit hyperactivity disorder, obsessive-compulsive disorder, post-traumatic stress disorder, substance abuse disorders and sexual dysfunction including premature ejaculation.
Patent NZ-520095-A (NZ)
Title: Novel Stra6 polypeptides, nucleic acids, antibodies, compositions and methods of treatments for inhibiting tumor cell growth
Inventor: PENNICA DIANE
IPC: C12N15/10
Filed: 2001-01-11
Abstract: An isolated nucleic acid molecule comprises DNA having at least 80% sequence identity to (a) a DNA molecule encoding a Stra6 polypeptide comprising the amino acid residues 1 to 667 of the sequence of Figure 2 (SEQ ID NO:2) or (b) a DNA molecule encoding a Stra6 polypeptide having amino acid residues from 1 to 658 of Figure 7 (SEQ ID NO:5) or (c) the complement of the DNA molecule of (a) or (b) wherein the isolated nucleic acid is other than DNA encoding murine Stra6 polypeptide an comprises at least 100 amino acids. Preferably the DNA sequence is that of Figure 1 (SEQ IDNO:1), Figure 6 (SEQ ID NO:4), the molecule deposited with the ATCC under the deposit numbers ATCC PTA 1181 or PTA 1405. Polypeptides, host cells, vectors and antibodies are described. An anti-Stra6 antibody can be used in diagnosing a tumor. An antibody or an antisense oligonucleotide that hybridizes to a nucleic acid that encodes the Stra6 polypeptide can be used in the preparation of a medicament for inhibiting the growth of tumor cells.
Patent NZ-521045-A (NZ)
Title: Motorcycling glove
Inventor: MAZZAROLO GIOVANNI
IPC: A41D19/00
Filed: 2001-03-15
Abstract: Motorcycling glove (1) comprising protective means (15-21) applied and one or more strips (22, 23) made from flexible materials for connecting together the protective means (15-21) which are positioned on one of the respective phalanges of two or more fingers and extending between adjacent fingers in order to prevent the rotation of the fingers of the glove (1) with respect to the fingers of the corresponding hand, wherein the said connecting strips (22, 23) has a common portion which is extending longitudinally with respect to the fingers and bears means for attachment to the glove (1) which do not affect the gripping action of the hand.
Patent NZ-521315-A (NZ)
Title: Exemestane for first-line treatment of breast cancer
Inventor: MASSIMINI GIORGIO
IPC: C07J1/00
Filed: 2001-02-20
Abstract: Disclosed is the use of exemestane for use in the first-line treatment of metastatic, advanced hormone-dependent breast cancer, wherein the pharmaceutical composition is suitable for oral administration and is in a unit dosage form for daily administration, the unit dosage form comprising an amount of exemestane of from about 5 to about 50mg, or for parenteral administration in a unit dosage form of about 50 to about 500 mg.
Patent NZ-526147-A (NZ)
Title: Compositions of pyrethroids and nicotinyl compounds for controlling parasitic insects and acarids
Inventor: ARTHER ROBERT G
IPC: A01N53/00
Filed: 2001-11-26
Abstract: Use of a combination of pyrethroids and nicotinyl compounds for the preparation of a product for the control of parasitic acarids on an animal or in a premise is disclosed.
Patent NZ-534952-A (NZ)
Title: Pyridinoylpiperidines as serotonin agonists and the use as medicaments for inhibition of neuronal protein extravasation, disorders due to dysfunction of the serotonin receptors and migraines
Inventor: COHEN MICHAEL PHILIP
IPC: A61P25/32
Filed: 2003-03-27
Abstract: 5-HT1F receptor agonists of formula I are described wherein: R1 is C1-C6 alkyl, substituted C1-C6 alkyl, C3-C7 cycloalkyl, substituted C3-C7 cycloalkyl, C3-C7 cycloalkyl-C1-C3 alkyl, substituted C3-C7 cycloalkyl-C1-C3 alkyl, phenyl, heterocycle or substituted heterocycle; R2 is hydrogen, C1-C3 alkyl, C3-C6 cycloalkyl-C1-C3 alkyl or a group of formula II; R3 is hydrogen or C1-C3 alkyl; R4 is hydrogen, halo or C1-C3 alkyl; R5 is hydrogen or C1-C3 alkyl; R6 is hydrogen or C1-C3 alkyl; and n is an integer from 1-6. Pharmaceutical compositions comprising the compounds are useful for activating 5-HT1F receptors, the inhibition of neuronal protein extravasation and for the treatment or prevention of migraines. Also described is a process for the production of the compounds.
Patent NZ-547963-A (NZ)
Title: Methods for producing copper ethanolamine solutions
Inventor: PATEL JAYESH P
IPC: C07F1/00
Filed: 2004-11-19
Abstract: A method for the production of an aqueous copper ethanolamine solution, comprising: a) providing in a vessel a mixture of: i) water; ii) an alkyl hydroxylamine, iii) an acid, an acid anhydride, or an alkyl hydroxylamine salt; and iv) a metallic copper bearing material; b) feeding oxygen into the mixture; c) maintaining the mixture at a temperature to dissolve metallic copper; and d) optionally removing excess metallic copper or other extraneous solids from the dissolved copper ethanolamine solution, thereby to form the copper ethanolamine solution; wherein oxygen is introduced into the vessel at a pressure of from about 5 to about 100 psig.
Patent NZ-550884-A (NZ)
Title: A platform formed from a folded blank
Inventor: DICKNER ALLAN
IPC: B65D/
Filed: 2005-04-27
Abstract: A platform formed of a blank 1 and loading ledges, the loading ledges each comprising a vertical portion 13 and a horizontal portion 14, the blank folding around the vertical and horizontal portions 13 14 of the loading ledges, the blank 1 having at least two openings to receive a central foot of one of the loading ledges in each opening.
Patent NZ-551780-A (NZ)
Title: Alkyl substituted indoloquinoxalines
Inventor: BERGMAN JAN
IPC: C07D/
Filed: 2005-05-18
Abstract: Disclosed is a substituted indoloquinoxaline of formula (I) wherein X is CO or CH2 and wherein the rest of the substituents are disclosed within the specification and pharmacologically acceptable salts thereof. Also disclosed is the use of a compound of formula (I) in the manufacture of a medicament for preventing and/or treating autoimmune diseases.
Patent NZ-555406-A (NZ)
Title: Cytotoxic agents comprising new taxanes
Inventor: MILLER MICHAEL L
IPC: A61K39/395
Filed: 2005-12-02
Abstract: Disclosed are Taxane compounds having the following formula (I) wherein R1 is a linker group comprising a disulfide group, or is an aryl or heterocyclic radical, alkyl alkenyl or alkynyl, cycloalkyl or cycloalkenyl, -OR2 or a carbamate formed from any of said, alkenyl or alkynyl, cycloalkyl or cycloalkenyl, or aryl or heterocyclyl; R2 is an alkyl, alkenyl or alkynyl, cycloalkyl or cycloalkenyl, aryl or heterocyclic; R3 is a linker group comprising a disulfide group, or is an aryl or heterocyclic, alkyl, alkenyl or alkynyl, cycloalkyl or cycloalkenyl; R4 is a linker group comprising a disulfide group, H, or is a hydroxy, an alkoxy, an alkenyloxy, an alkanoyloxy, aroyloxy, alkenoyloxy, alkynoyloxy, cycloalkanoyloxy, alkoxyacetyl, alkylthioacetyl, alkyloxycarbonyloxy, cycloalkyloxy, cycloalkenyloxy, carbamoyloxy, alkylcarbamoyloxy, or dialkylcarbamoyloxy, a heterocyclic or aryl ether, ester or carbamate, or alkyl or alkenyl ester or ether or a carbamate of the formula -OCOX, wherein X is a nitrogen-containing heterocycle or a carbamate of the formula -OCONR9R10, wherein R9 and R10 are the same or different and are H, alkyl or aryl; R8 or R7 is H; Ra is H; R7 or R8 and R form a bond (cyclic ether); Ra = aryl or heterocyclic radical; and wherein R, or R3 or R4 represents said linking group. Also disclosed is a cytotoxic agent comprising said taxane and a cell binding agent e.g. an antibody.
Patent NZ-556581-A (NZ)
Title: Conjugates of a polypeptide and an oligosaccharide
Inventor: BOS EBO SYBREN
IPC: A61K47/48
Filed: 2006-01-31
Abstract: Disclosed is a conjugate of a polypeptide and an oligosaccharide. The polypeptide is conjugated to at least one oligosaccharide-spacer residue. The oligosaccharide is a synthetic sulfated oligosaccharide comprising 4-18 monosaccharide units and per se having affinity to antithrombin III and the spacer is a bond or an essentially pharmacologically inactive flexible linking residue, or a pharmaceutically acceptable salt thereof. Use of the conjugate in the manufacture of a medicament and the preparation of the conjugate is also disclosed.
Patent NZ-556639-A (NZ)
Title: Chromatographic media
Inventor: DEORKAR NANDU
IPC: B01J20/22
Filed: 2005-12-16
Abstract: The disclosure relates to chromatographic media comprising epoxidized or halogenated polymeric resin particles derivatized by reaction with polyethyleneimine on the surface of the polymer and wherein the epoxidized or halogenated polymeric particles are epoxidized or halogenated polyacrylates or polymethacrylates, wherein the polymeric resin particles derivatized with polyethyleneimine on the surface of the polymer are functionalized by reaction of a functionalization reagent with terminal amino groups of the polyethyleneimine on the surface of the polymeric resin, and wherein the functionalization reagent is selected from the group consisting of: acid anhydrides, sulfonation agents, alkyl chlorides, alkyl anhydrides and alkyl chlorides containing quaternary ammonium functionality, and mixtures thereof. Also disclosed are chromatographic columns backed with said media and a process for separation of components of solution using a column containing said media.
Patent NZ-564023-A (NZ)
Title: Crystalline modifications to pyraclostrobin
Inventor: ZIEGLER HANS
IPC: A01N43/56
Filed: 2006-06-19
Abstract: Disclosed is a crystalline modification IV of pyraclostrobin which, in an X-ray powder diffractogram at 25°C, shows at least three of the following reflexes: d = 6.02 ± 0.01 Å, d = 4.78 ± 0.01 Å, d = 4.01 ± 0.01 Å, d = 3.55 ± 0.01 Å and d = 3.01 ± 0.01 Å. Also disclosed is a process for preparing a crystalline modification IV of pyraclostrobin as defined above, which comprises: i) dissolving a pyraclostrobin form different from modification IV in an organic solvent or solvent mixture, where the organic solvent or solvent mixture comprises at least 70% by volume of at least one fully water-miscible organic solvent L1 (such as methanol, ethanol, acetone or butanone) and if appropriate up to 30% by volume of water; and ii) effecting crystallization of pyraclostrobin over a period of at least 10 h and/or in the presence of seed crystals of modification IV.
Patent NZ-567216-A (NZ)
Title: Encapsulation system
Inventor: VASCONCELLOS ALFRED
IPC: A61K9/50
Filed: 2006-10-24
Abstract: A composition comprising alginate containing between from about 50% to about 95% mannuronic acid residues and a polycation having an average molecular weight of 10 to 40 kDa and a polydispersity index of less than about 1.5; wherein the polycation is not poly-L-Iysine. The composition is particularly useful for making biocompatible microcapsules containing living cells for allo- or xeno-transplantation. Such microcapsules have enhanced durability and can maintain their structural and functional integrity over long periods of time compared to prior art alginate microcapsules.
Patent NZ-570532-A (NZ)
Title: A housing containing a chamber with a flexible reservoir of active agents delivered via a needle to the skin
Inventor: MODI PANKAJ
IPC: A61J1/10
Filed: 2007-02-15
Abstract: A multi-use injection device for multiple delivery of a fluid drug is disclosed. The device uses a disposable, prefilled, flexible bladder reservoir (70) filled with the fluid drug that is punctured by a re-usable, non-removable needle (72) on activation by an actuator (80). The device has a reusable housing (52) with an upper end (54) and a lower end (56), the upper end (54) being associated with the actuator (80) having a plunger (86). A reservoir chamber (62) is formed by the upper end (54) of the housing (52) and the lower end of the actuator which is used to contain the bladder reservoir (70). The needle (72) is mounted so as to be transverse to the base (64) of the reservoir chamber (62) and has an upper top end and a lower tip. When pressure is applied to the actuator (80), the bladder reservoir (70) is moved down within the reservoir chamber (62) and punctured by the top end of the needle (72), releasing the contents into the needle (72).
Patent NZ-570971-A (NZ)
Title: N-Hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors
Inventor: TOSCANO JOHN P
IPC: A61P9/04
Filed: 2007-03-16
Abstract: Disclosed is a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein: R1 is H; R2 is H; R3, R4, R5, R6 and R7 are independently selected from H, halo, perfluoromethyl and alkylsulfonyl e.g. 2,6-dichloro-N-hydroxy benzene sulphonamide for treating heart failure
Patent NZ-571415-A (NZ)
Title: Learning aid with keys that are placed in one of three positions to display the use of a number in calculations
Inventor: SANGSTER MAHRIA LYN
IPC: G09B1/00
Filed: 2008-09-22
Abstract: A mathematics learning aid (1) is disclosed. The learning aid (1) may be used to teach addition, subtraction, multiplication, or division. The aid (1) has a mounting (3) with a plurality of keys (5) attached to it. Each key (5) can be pivoted individually into three positions and positively secured in at least two of the three positions. A number of methods that use the aid (1) in teaching mathematics are disclosed.
Patent NZ-572627-A (NZ)
Title: Selecting memory locations within a power system device or fault indicator for viewing
Inventor: PARK DOUGLAS A
IPC: G06F11/273
Filed: 2007-05-18
Abstract: A system for wirelessly viewing memory locations within a power system device comprising a wireless device (102), at least one randomly accessible memory location, a processor (310) coupled to the randomly accessible memory location and a radio frequency transmitter and receiver (RX, TX) coupled to the processor (310). The wireless device further includes an input mechanism for accepting an input from a user indicative of the memory location they wish to view, a radio frequency transmitter and a radio frequency receiver. The transmitter of the wireless device is adapted to transmit a first signal, which includes the memory location within the power system that the user wishes to view, to the receiver (RX) coupled to the processor (310). The processor (310) can then retrieve the value of the memory location indicated in the first signal from the randomly accessible memory location and transmit a second signal, which includes the value of the memory location, via the radio frequency transmitter (TX) connected to the processor (310) to the receiver of the wireless device (102).
Patent NZ-576387-A (NZ)
Title: PFC booster circuit
Inventor: HARRISON MICHAEL JOHN
IPC: G05F1/70
Filed: 2009-04-20
Abstract: Disclosed is a power factor correction booster circuit for connection to an alternating current (AC) power source. The circuit including a first circuit portion arranged to be active over a first AC half cycle of the power source, the first circuit portion including: a first AC input node (IN1) in connection with a source node of a first power transistor (PT1), a first node of an inductive element (L1) in connection with a drain node of the first power transistor, a second node of the inductive element in connection with a drain node of a second power transistor (PT2), a second AC input node in connection with a source node of the second power transistor, an anode of a first semiconductor diode element (D2) in connection with the second node of the inductive element, a cathode of the first semiconductor diode element in connection with a first node of a first output capacitor element (C2), and a second node of the first output capacitor element in connection with a second AC input node (IN2). The first and second power transistors are controllable to switch the first circuit portion between a forward mode and a flyback mode, such that in the forward mode the inductive element stores energy from the AC power source, and in the flyback mode the stored energy from the inductive element is transferred to the first output capacitor through the first semiconductor diode element.