baber/WOPTO huggingface dataset:
Patent NZ-501837-A (NZ)
Title: Retentate chromatography and protein chip arrays characterised in combinational separation which includes separation and detection of multiple analytes in parallel
Inventor: HUTCHENS T WILLIAM
IPC: G06F19/00
Filed: 1998-06-19
Abstract: A method for identifying analytes that is differentially present in a first and second biological sample comprising the steps of: (a) selecting a plurality of different selectivity conditions to which the first and second samples will be exposed, wherein (i) each selectivity condition is defined by an adsorbent and an eluant; (ii) each different selectivity condition comprises a different adsorbent and the same or different eluant; and (iii) exposing a sample to a selectivity condition  comprises contacting a sample with an adsorbent bound to a substrate and washing the adsorbent with an eluant to allow retention of analytes in the sample by the adsorbent; (b) detecting analytes in the first sample by (i) exposing the first sample, in parallel, to each of the different selectivity conditions, and (ii) detecting analytes retained by the adsorbents by desorption spectrometry comprises desorbing and ionizing the analyte from the adsorbent with an energy source and detecting the desorbed and ionized analytes with a detector; (c) detecting analytes in the second sample by (i) exposing the second sample, in parallel, to each of the different selectivity conditions, and (ii) detecting analytes retained  by the adsorbents by desorption spectrometry; and (d) comparing the analytes detected in the first biological sample with analytes detected in the second biological sample to identify analytes that are differentially present in the first and second biological sample. The method is suitable for retentate chromatography. It provides a unified analyte detection and functional analysis capability for biology and medicine that is characterised by a single, integrated operating system for the direct detection of analyte expression patterns associated with gene function, protein function, cell function, and the function of whole organisms.
Patent NZ-504771-A (NZ)
Title: IFNAR2/ INFcomplex for prolonging the in vivo effects of type I interferon (INF)
Inventor: TEPPER MARK
IPC: C07K19/00
Filed: 1998-12-18
Abstract: A molecule comprising a complex of a Type I interferon (IFN) and a subunit of the human interferon a/b receptor (IFNAR), which is capable of binding to the Type I IFN of the complex, for use in the manufacture of a medicament for prolonging the effect of Type I IFN.
Patent NZ-505214-A (NZ)
Title: Retaining wall block with pin holes in the top surface of the block for receiving pins and pin holes cavities on the bottom surface to receive the pins of a corresponding block
Inventor: RACE ROBERT J
IPC: E02D/
Filed: 1999-08-12
Abstract: A retaining wall block (1) has parallel top and bottom faces, a front face (4), a rear face (5), first and second side wall faces (6, 7) and a vertical plane of symmetry (S) extending between the front and rear faces (4, 5). The block (1) is formed as a body portion (8) including the front face (4), a head portion (9) including the rear face (5) and a neck portion (10) connecting the body portion (8) and the head portion (9). The body, head and neck portions (8, 9, 10) each extend between the top and bottom faces and between the first and second side wall faces (6, 7). An opening (13) extends through the neck portion (10) from the top face (2) to the bottom face, dividing the neck portion (10) into first and second neck wall members (14, 15) extending rearwardly from the body portion (8) to the head portion (9). First and second pin holes (16, 17) are each disposed in the body portion (8) and open onto the top face (2), where the first and second pin holes being configured for receiving a pin with a free end of the pin protruding beyond the top face.
Patent NZ-509067-A (NZ)
Title: Densifying of a bulk particulate material
Inventor: RUSSEL-SMITH KEVAN VAUGHAN
IPC: B65G69/20
Filed: 1999-06-25
Abstract: A method of densifying a bulk particulate material, the method including at least partially confining the bulk particulate material and rotating a rotatable member (14) submerged in the bulk particulate material about an axis of rotation (16) to cause movement of the material particles essentially towards or away from the axis of rotation, thereby to provide a densified bulk particulate material.  The method is particularly suitable for densifying silica fume.  The invention extends to apparatus for densifying a bulk particulate material.
Patent NZ-509764-A (NZ)
Title: Continuous flow reactor having at least three slit shaped reaction chambers arragned in parallel to one another
Inventor: SCHUTTE RUDIGER
IPC: B01J19/32
Filed: 1999-08-28
Abstract: The invention relates to a process for carrying out gas-liquid reactions in a continuous flow reactor having several reactor chambers arranged parallel to one another, open in the direction of flow. The space-time yield can be increased in that a reactor is used with at least three chambers, the ratio of chamber width b to slit width s of which is, on average, greater than 3 and the slit width s of which is in the range of 5 to 100 mm. Preferably, s is in the range of 5 to 50 mm and s/b in the range of 5 to 100. The continuous flow reactor according to the invention with the at least three reactor chambers and the above ratio s/b is preferably tubular and contains one or more plate stacks
Patent NZ-523120-A (NZ)
Title: Volumetric liquid metering device
Inventor: JACEK STANLEY JOHN
IPC: G01F3/38
Filed: 2001-05-11
Abstract: A volumetric liquid metering device has meter chamber 50 for receiving up tot and including a predetermined volume of liquid, an inlet conduit 46 for directing liquid into the meter chamber, a volumetric metering means 58 to indicate when the predetermined volume of liquid has entered the meter chamber, and a discharge conduit 64 for discharging liquid from the meter chamber in response to a signal from the volumetric metering means.
Patent NZ-525381-A (NZ)
Title: Rotation of ground contacting wheel causing rotation of further wheel via closed hydraulic circuit
Inventor: DOWLING KEITH WILLIAM
IPC: B60K17/10
Filed: 2001-09-20
Abstract: Hydraulically driven apparatus where the rotation of a ground contact wheel (3) automatically rotates a second device requiring drive (5) via a circuit and hydraulic motors (not shown) attached to the wheel (3) and second device (5), respectively. The apparatus can be used in many applications including in one embodiment used as a transmission system to drive a rotary broom (5) of a sweeping apparatus.
Patent NZ-527066-A (NZ)
Title: Method for producing the anticholinergic agent tiotropium bromide
Inventor: BANHOLZER ROLF
IPC: A61P25/00
Filed: 2001-12-12
Abstract: A process for the production of tiotropium bromide of formula (I) is disclosed.
Patent NZ-529149-A (NZ)
Title: Apparatus and method for nasal rinse
Inventor: MEHTA KETAN C
IPC: A61M3/02
Filed: 2002-04-25
Abstract: An apparatus and method for preparing a pH balanced saline solution and using the saline solution for rinsing a nasal passage. The apparatus includes a container (30) having flexible sidewalls and an opening for a removable cap (20). The cap has a rounded convex upper portion curving away from an opening (15) at the cap's uppermost surface and has a conduit (55) in the cap's interior, which conduit extends into the container when the apparatus is fully assembled or is connected to a tube (35) that extends in the container. A saline solution is prepared by adding sodium chloride and sodium bicarbonate to distilled water. The sidewalls of the container, filled with the saline solution, are compressed to urge the saline solution through the conduit, or tube and conduit, and through the opening in the cap and into a nasal passage, the cap being pressed against a nostril to provide a comfortable and effective seal.
Patent NZ-530199-A (NZ)
Title: Compositions for removing human cerumen
Inventor: CAGLE GERALD D
IPC: A61K9/00
Filed: 2002-06-21
Abstract: A composition is disclosed to assist in the removal of human cerumen from the external ear canal. It is described to comprise of a cerumenolytically acceptable enzyme and a bicarbonate in effective amounts, and an aqueous otologically acceptable vehicle. The enzyme can be selected from the group consisting of lipases, proteases, amylases. The possibility of replacing the cerumenolytically acceptable enzyme with a proteolytic enzyme is also disclosed, and this can be selected from the group including pancreatin, trypsin, subtilisin, collagenase, keratinase, carboxypeptidase, and papain. When sodium bicarbonate is used, the amount disclosed to be effective is about 0.5 to about 15 weight/volume percent. A two-part composition is also described involving the enzyme and aqueous otologically acceptable vehicle including a bicarbonate wherein the first and second parts are maintained separate until desired to administer to the external ear canal.
Patent NZ-534255-A (NZ)
Title: Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders
Inventor: ZHANG CHENGZHI
IPC: C07D409/04
Filed: 2003-02-21
Abstract: Disclosed are benzofuran and benzothiophene derivatives of formula I and their use for the treatment of hyper-proliferative disorders.
Patent NZ-537372-A (NZ)
Title: Sample extraction system
Inventor: WADE ROBERT ANDREW
Filed: 2004-12-23
Abstract: The present invention relates to a sample extraction system to be interfaced with a sampling device. The sampling device includes a capture material located within the interior of a sampling chamber. The sample extraction system provided includes at least one carrier fluid supply adapted to introduce at least one carrier fluid flow into the interior of the sampling chamber and at least one inlet port adapted to receive a sample fluid flow from the interior of the sampling chamber and at least one energy supply system adapted to facilitate the extraction of at least one sampled compound from the capture material within the sampling chamber and a thermal control system adapted to heat or cool the exterior of the sampling chamber and a data capture system configured to receive data transmitted from a sampling device interfaced with the sample extraction system.
Patent NZ-541439-A (NZ)
Title: (E)-3-[4-(2,6-Difluoro-phenylamino)-6-(4-fluoro-2-methyl-phenyl)-2-methylsulfanyl-pynimidin-5-yl]-acrylic acid ethyl ester
Inventor: ADAMS JERRY L
Filed: 2001-10-23
Abstract: A group of 2,4,8-trisubstituted-8H-pyrido[2,3- djpyrimidin-7-one compounds and processes for the preparation thereof is described. In particular a compound of formula III wherein R1 is an aryl or heteroaryl ring, which ring is optionally substituted; R3 is a C1-10 alkyl, C3-7 cycloalkyl, C3-7 cycloalkylalkyl, aryl, arylC1-10 alkyl, heteroaryl, heteroarylC1-10 alkyl, heterocyclic, or a heterocyclylC1-10 alkyl moiety, which moieties are optionally substituted; R12 is a C1-10 alkyl, aryl, heteroaryl, or arylalkyl; m is 0 or an integer having a value of I or 2; and Rg is a C1-4 alkyl. Also described is the use these compounds in treating CSBP/p38 kinase mediated diseases and pharmaceutical compositions for use in such therapy.
Patent NZ-542148-A (NZ)
Title: Methods and compositions for the enzymatic synthesis of gangliosides
Inventor: DEFREES SHAWN
IPC: C07D/
Filed: 2004-03-04
Abstract: Disclosed is a compound having formula (I) wherein: Z is a member selected from O, S, C(R2)2 and NR2; X is a member selected from H, -OR3, -NR3R4, -SR3 and -CHR3R4; Y is a member selected from H, -OR7, -SR7, -NR7R8, substituted or unsubstituted alkyl, alkenyl, alkynyl, heteroalkyl, aryl, heteroaryl, or heterocycloalkyl; R1 is of the formula -C(R11)=CR12R13; and the remaining substituents are as disclosed in the specification. Compounds of the formula disclosed are useful in the prevention or treatment of disorders of the nervous system.
Patent NZ-542273-A (NZ)
Title: Use of a pharmaceutical composition comprising collodial silicon dioxide
Inventor: HAEBERLIN BARBARA
IPC: A61P17/02
Filed: 2002-09-27
Abstract: Discloses Is the use of a pharmaceutical composition, which is a dispersible tablet, comprising rapamycin or a rapamycin derivative and 1 to 5 % of colloidal silicon dioxide for the manufacture of a medicament for treating or preventing cell, tissue or organ allo- or xeno-transplant rejection, autoimmune diseases, inflammatory conditions, asthma, chronic graft rejection, restenosis, cancer, hyperproliferative skin disorder, inflammation or for treating infections.
Patent NZ-542310-A (NZ)
Title: Improved waste treatment and disposal system
Inventor: NASSEF NAMON A
IPC: B61D35/00
Filed: 2004-02-05
Abstract: Waste, including sanitary, petroleum, and other organic wastes from portable and remote waste generating sources, such as passenger carrying vehicles and remote facilities where sewage and septic systems are impractical, is treated and disposed of. The treatment system (100) makes use of thermal energy liberated from devices that generate a hot exhaust stream, such as internal combustion engines, and generally involves the passing of a waste material from a tank (1) through a homogenizing device (9). The homogenizing device reduces the particle size and thoroughly mixes the waste stream so that it may be injected into a hot exhaust stream (22), which converts the waste stream into water vapour, gas and inert ash.
Patent NZ-545149-A (NZ)
Title: Call centre call handling
Inventor: SMITH BRYAN LESLIE
Filed: 2006-02-07
Abstract: An SMS or MMS message call centre for responding to digitally recorded messages received from callers is provided. The call centre includes a message recording database which records the called number, the calling number, the message and a message status, as well as a message parser which separates the messages and a message relayer to relay messages to the operator for reply to the message. Additonal filed as 566792
Patent NZ-547077-A (NZ)
Title: An oral product comprising an amount of a metal-binding peptide which is effective for oral care
Inventor: BAR-OR DAVID
IPC: A61K38/00
Filed: 2002-11-19
Abstract: An oral care product comprising an amount of a metal-binding peptide which is effective for oral care, the peptide having attached thereto a non-peptide, metal-binding functional group, and the peptide containing from 2-10 amino acids.
Patent NZ-554308-A (NZ)
Title: Adjustable bone plate
Inventor: RALPH JAMES D
IPC: A61B17/58
Filed: 2005-10-24
Abstract: A bone plate assembly 100 that is adjustable in length and has a longitudinal curvature includes first and second longitudinal plates 102, 104 one having a pair of prongs 108 and the other having a pair of bores in which the prongs can be smoothly slid to adjust the length of the assembly. The length of the assembly can be fixed by a locking mechanism that separates the prongs to force the prongs against the inner surfaces of the prong bores. The distal ends of the respective plates include apertures 114 through which screws can be inserted to fasten the plates to the bone sections, and the fracture site can be observed through a window 110 defined between the prongs and the plates.
Patent NZ-556272-A (NZ)
Title: Heterocyclic tetracyclic tetrahydrofuran derivatives as 5HT2 inhibitors in the treatment of CNS disorders
Inventor: CID-NUNEZ JOSE MARIA
IPC: A61K31/38
Filed: 2006-01-25
Abstract: Disclosed are condensed tetracyclic compound according to Formula (I) which are useful for the prevention and/or treatment of conditions mediated through the 5HT2 receptor, in particular 5HT2A and 5HT2C receptor and D2 receptor, as well as through the norepinephrine reuptake inhibition, wherein: Y represents O; X represents CR6R7, O, S, S(=O), S(=O)2 or NR8; and the other substituents are disclosed herein. Also disclosed is the use of a compound as defined above for the manufacture of a medicament for the treatment and/or prevention of central nervous system disorders like anxiety, depression and mild depression, bipolar disorders, sleep- and sexual disorders, psychosis, borderline psychosis, schizophrenia, migraine, personality disorders, obsessive-compulsive disorders, social phobias, panic attacks, attention disorders, organic mental disorders, mental disorders in children, aggression, memory disorders and attitude disorders (especially in older people), addiction, obesity, bulimia and similar disorders.
Patent NZ-565378-A (NZ)
Title: Phosphoramidate alkylator prodrugs
Inventor: MATTEUCCI MARK
IPC: A61K33/243
Filed: 2006-06-29
Abstract: Disclosed are phosphoramidate derivatives as represented by the general formula (I), wherein Y2 is O, S, NR6, NCOR6, or NSO2R6 wherein each R6 is alkyl, heteroalkyl, aryl or heteroaryl; R1 has the formula L-Z3; and wherein the remaining substituents are as defined herein; or a pharmaceutically acceptable salt thereof, for use in the treatment of cancer.
Patent NZ-573071-A (NZ)
Title: Method for fabricating a compressible object to be used in a wellbore
Inventor: POLIZZOTTI RICHARD S
IPC: E21B43/10
Filed: 2007-05-04
Abstract: Disclosed is a method for fabricating a compressible object such as the one that may be used in a wellbore. The method comprises the following steps: Step 1: Selecting a depth range and/or corresponding pressure range in a wellbore at which a compressible object is to be utilised. Step 1 (above) further includes the steps of i) Selecting an architecture for the compressible object based on a model, the architecture comprising a hollow shell defining an enclosed interior region; ii) Selecting a wall material for the shell of the compressible object, the wall material consisting of material having an elastic tensile strength of at least 10,000 psi (68.9 Mpa); and iii) Selecting an interior pressure for the compressible object that is about equal to the lower limit of the pressure range. Step 2: Numerically modelling the compressibility of the compressible object and balancing the compressibility of the compressible object with the corresponding pressure range of the selected depth using the model. Step 3: Selecting a design for the compressible object such that the compressible object begins compression at or near the selected depth range. Step 4: Forming the compressible object with an interior region of the hollow shell. The interior region of the hollow shell is pressurised to the selected internal pressure. The selected pressure is such that the wall material and internal pressure provide a non-linear compressibility of the object in response to changes in external pressure that does not cause the wall material to exceed the maximum elastic strain of the wall material.
Patent NZ-575685-A (NZ)
Title: Novel benzofuran potassium channel blockers and uses thereof
Inventor: FLYNN BERNARD LUKE
IPC: A61P3/10
Filed: 2007-10-04
Abstract: Disclosed is a substituted benzofuran compound of formula (I) where the substituents are as disclosed in the specification. Examples of compounds of formula (I) are 5-Acetyl-4, 7 -dimethoxy-6-(3-(phenyl)propoxy)benzofuran; 5-Acetyl-4, 7 -dimethoxy-6-( 4-(phenoxy)butoxyl)benzofuran and 5-Acetyl-6-(3-phenylpropoxy)benzofuran. Also disclosed is a pharmaceutical composition comprising a compound of formula (I), the use of a compound of formula (I) in the manufacture of a medicament for treating or prevention of autoimmune or chronic inflammatory diseases, or the prevention of rejection of foreign organ transplants and/or related afflictions and a method of intentionally modulating potassium ion channel activity of T-cells ex-vivo by the application of a compound of formula (I) or a pharmaceutically acceptable salt thereof, to said T -cells.
Patent NZ-580124-A (NZ)
Title: New antitumoral compounds
Inventor: FERNANDEZ DONIS ARIADNA
IPC: A61K38/00
Filed: 2004-09-09
Abstract: Provided is a compound which is according to Kahalalide F other than having an amino acid in the cyclic part differing from that in kahalalide F wherein the amino acid L-Phe at position 3 of the cyclic part is substituted by another natural or non natural amino acid, andlor masked with one or more substituent organic groups; and which compound may, optionally, also differ in the side-chain by the modification of the terminal acyl group; or a pharmaceutically acceptable salt thereof. The compound can be used in the treatment of cancer. (62) Divided Out of 545700
Patent NZ-580187-A (NZ)
Title: Defined medium for enumeration of campylobacter
Inventor: THOMAS ALASTAIR OWEN
IPC: C12N1/20
Filed: 2009-10-05
Abstract: Provided is a culture medium for the growth and enumeration of Campylobacter colonies comprising: (a) a nutrient medium with an energy source effective to support growth and colony formation of Campylobacter; (b) a reducing agent selected from the group comprising a metabisulfite salt, a bisulfite salt, pyruvic acid, a pyruvate salt and mixtures thereof; and (c) a tetrazolium-containing compound wherein the culture medium is chemically defined.
Patent NZ-581542-A (NZ)
Title: Treatment and prevention of influenza
Inventor: MOORE ROBERT JOHN
IPC: A23L13/50
Filed: 2008-05-16
Abstract: Disclosed is a nucleic acid construct encoding three RNA molecules comprising a double-stranded region, wherein the RNA molecule reduces influenza A virus replication in an animal cell and/or reduces production of infectious influenza A virus particles in an animal cell and/or reduces the expression of an influenza A virus polypeptide in an influenza A virus infected animal cell when compared to an isogenic influenza A virus infected animal cell lacking the RNA molecules, wherein the double-stranded regions comprise nucleotide sequences at least 95% identical to sequences selected from: (i) SEQ ID NO:6, SEQ ID NO:7 and SEQ ID NO:8, and (ii) SEQ ID NO:7, SEQ ID NO:9 and SEQ ID NO:12. Also disclosed is the use of the nucleic acid construct in the manufacture of a medicament for treating and/or preventing influenza A virus infection.
Patent NZ-583431-A (NZ)
Title: Fence wire strainer
Inventor: WOOSTER MAURICE WILLIAM
IPC: B21F9/00
Filed: 2008-08-27
Abstract: A wire strainer for straining a fence wire, wherein the wire strainer includes: (i) a frame; (ii) a spool having a shaft rotatably mounted to the frame; (iii) ratchet means adapted to selectively allow the spool to rotate only in a desired direction when the wire is to be tensioned and/or retained in a tensioned state and able to free wheel when the wire is not required to be in a tensioned state; and (iv) a projection (36) and a two plane guide means (37) situated on the spool. The projection is positioned and adapted to engage with a portion of a wire and the two plane guide means is positioned and adapted to assist in deflecting the length of wire not engaged with the projection away from the projection as the spool is rotated during the straining of a wire. (62) Divided Out of 570800