baber/WOPTO huggingface dataset:
Patent EP-4014039-A1 (EP)
Title: Cells highly sensitive to clostridial neurotoxin
Inventor: OYLER GEORGE A
IPC: C07K14/33
Filed: 2020-08-13
Abstract: A method for making a population of cells that are highly sensitive to clostridial neurotoxin, the method comprising: (a) contacting recombinant cells that express an indicator protein with clostridial neurotoxin; and (b) following such contact, selecting the cells that exhibit cleavage of the indicator protein. A cell from the population produced using the aforementioned method. An assay for determining the activity of a modified or recombinant neurotoxin comprising contacting such a cell with the modified or recombinant neurotoxin under conditions and for a period of time sufficient to allow the protease domain of a wild-type clostridial neurotoxin to cleave the indicator protein in the cell and determining the presence of product resulting from the cleavage of the indicator protein.
Patent EP-4045492-A1 (EP)
Inventor: JELINKOVA KATERINA
IPC: A61K31/395
Filed: 2020-09-18
Abstract: La présente invention concerne des sels d'omecamtiv mecarbil avec de l'acide méthane sulfonique, de l'acide benzènesulfonique et de l'acide p-toluènesulfonique et leurs procédés de préparation.
Patent EP-3950758-A1 (EP)
Inventor: FUKUDA KAZUYUKI
IPC: D06N3/14
Filed: 2020-03-26
Abstract: A cross-linking agent for a fiber or leather includes a blocked isocyanate in which an insocyanate group of a hydrophilic group-containing polyisocyanate being reaction product of a polyisocyante and a hydrophilic group-containing active hydrogen compound is blocked by a blocking agent. The blocking agent contains a secondary amine compound in which two carbon atoms are directly bonded to a nitrogen atom of a secondary amine, and at least one of the two hydrocarbon atoms is a tertiary carbon atom.
Patent EP-4042372-A1 (EP)
Title: Segmentation d'une image médicale
Inventor: SCHULZ HEINRICH
IPC: G06T7/12
Filed: 2020-10-08
Abstract: Dans un procédé de segmentation d'une image médicale, une segmentation de l'image médicale est affichée (102) à un utilisateur, la segmentation comprenant un contour représentant une caractéristique dans l'image médicale. Une entrée utilisateur est ensuite reçue (104), l'entrée utilisateur indiquant une correction du contour dans la segmentation de l'image médicale. Une contrainte de forme est déterminée (106) à partir du contour et de la correction indiquée au contour et la contrainte de forme est fournie (108) en tant que paramètre d'entrée à un modèle de segmentation pour effectuer une nouvelle segmentation de l'image médicale.
Patent EP-4048693-A1 (EP)
Title: Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
Inventor: MENG RAYMOND D
IPC: A61P35/00
Filed: 2020-09-25
Abstract: The invention provides methods of dosing for the treatment of cancers. In particular, provided are methods for treating human patients having lung cancer, such as non-small cell lung cancer (NSCLC), by administering a combination of an anti-TIGIT antagonist antibody (in particular tiragolumab) and a PD-1 axis binding antagonist (in particular atezolizumab).
Patent EP-3959266-A1 (EP)
Inventor: RASZEWSKI JARED R
IPC: C08L101/16
Filed: 2020-06-24
Abstract: L'invention concerne des films et des matériaux d'emballage comprenant des composants biodégradables et comestibles et des capsules créées à l'aide de ces matériaux.
Patent EP-3955766-A1 (EP)
Inventor: AYDIN ORHAN
IPC: A44B1/02
Filed: 2020-04-14
Abstract: The invention relates to an elastic textile accessory (1) made from flexible or elastic silicone, thermo rubber or derivative materials to be fixed on developed textile material for use in matching socks pairs before or after washing. Instead of shirts buttonhole or knots, bras hooks connections. In order to achieve this purpose elastic textile accessory (1) of the invention developed to be used in textile products comprises elastic button (2) fixed onto textile product by hot press gluing or micro injection press method or sewing and elastic button hole (3) matching the button (2) and fixed onto textile product by using one of said methods.
Patent EP-3936299-A1 (EP)
Inventor: KURIHARA FUMIO
IPC: B29C39/26
Filed: 2020-03-24
Abstract: Provided is a resin molding method capable of reducing the use amount of micropellets and obtaining a resin molded article having required characteristics. A resin molding method includes a disposing step of disposing a preliminary molded body (2) laminated and formed in a three-dimensional shape in a molding die (3), a filling step of heating and melting the preliminary molded body (2) by an electromagnetic wave transmitted through the molding die (3) and filling the molding die (3) with a molten resin material (20), and a cooling step of cooling and solidifying the molten resin material (20) in the molding die (3). In the cooling step, a resin molded article integrated so as to eliminate a lamination interface (21) of the preliminary molded body (2) is formed in the molding die (3).
Patent EP-3960258-A1 (EP)
Inventor: FUKUSHIGE JUNYA
IPC: A63F13/428
Filed: 2020-06-22
Abstract: An image of an augmented reality space, in which a character is arranged with respect to an acquired image acquired by the imaging sensor, is displayed on the display unit, and the behavior of the character in the augmented reality space is produced on the basis of data transmitted from an external source, wherein the data is motion data and sound data that are input by a performer who plays live as the character.
Patent EP-4041563-A1 (EP)
Inventor: DINESCU LIVIU
IPC: B41M5/52
Filed: 2020-10-08
Abstract: L'invention concerne des compositions de revêtements récepteurs d'encre comprenant : (a) une dispersion aqueuse de polyuréthane anionique ; et (b) une solution aqueuse d'un polyuréthane non ionique. L'invention concerne également des procédés de revêtement de substrats, ainsi que d'impression, comprenant la fourniture et/ou le revêtement de la composition sur un substrat.
Patent EP-3937580-A1 (EP)
Inventor: YANG SUCKCHEL
IPC: H04L1/00
Filed: 2020-05-04
Abstract: Disclosed are a method and a device for transmitting or receiving a signal in a wireless communication system according to an embodiment of the present invention, the method comprising: performing a random access channel (RACH) procedure; receiving configuration information related to a terminal on the basis of the RACH procedure; receiving downlink control information (DCI) for scheduling a single physical uplink shared channel (PUSCH) or multiple PUSCHs to be transmitted in one serving cell, on the basis of the configuration information; and transmitting the single PUSCH or the multiple PUSCHs in the serving cell on the basis of the DCI, wherein a payload size of the DCI may be determined on the basis of the greater number of bits between the number of bits of pieces of information for scheduling the single PUSCH and the number of bits of pieces of information for scheduling the multiple PUSCHs.
Patent EP-4049083-A1 (EP)
Inventor: KLEIJN STEVEN EVERARD FILIPPUS
IPC: H01S5/34
Filed: 2020-10-16
Abstract: Des exemples de l'invention concernent un procédé de fabrication d'une structure semi-conductrice dotée de multiples puits quantiques. Le procédé comprend les étapes consistant à : fournir un substrat comprenant un composé semi-conducteur binaire ayant une première constante de réseau ; déposer au moins : une première couche sur le substrat, la première couche d'un premier alliage semi-conducteur comprenant InP, et une deuxième couche en contact avec la première couche, la deuxième couche d'un deuxième alliage semi-conducteur comprenant InP, pour former un premier empilement de couches semi-conductrices sensiblement planes sur le substrat ; déposer, en contact avec le premier empilement, une troisième couche d'un composé semi-conducteur binaire ayant la première constante de réseau ; déposer au moins : une quatrième couche sur la troisième couche, la quatrième couche comprenant un troisième alliage semi-conducteur comprenant InP, et une cinquième couche en contact avec la quatrième couche, la cinquième couche comprenant un quatrième alliage semi-conducteur comprenant InP, pour former un second empilement de couches semi-conductrices sensiblement planes sur la troisième couche.
Patent EP-3967587-A1 (EP)
Title: Leanable vehicle equipped with rider assistance control device for obstacles
Inventor: YASUKAWA RISA
IPC: B60T7/12
Filed: 2020-05-11
Abstract: A driving assist control device 1011 for obstacles, which is included in a leaning vehicle 1001, is configured to control the assisting braking force so that at least one of the relationship 1 and the relationship 2 described below is established. Relationship 1: in a state in which braking force including the assisting braking force is generated by both a front wheel brake and a rear wheel brake or by only the front wheel brake, based on at least the front wheel brake operation amount and a margin obtained based on the relationship between the obstacle 2001 and the host vehicle 1001, at least the front wheel braking force generated by the front wheel brake is decreased in response to the decrease in a front wheel brake operation amount. Relationship 2: in a state in which braking force including the assisting braking force is generated by both a front wheel brake and a rear wheel brake or by only the rear wheel brake, based on at least the rear wheel brake operation amount and a margin obtained based on the relationship between the obstacle and the host vehicle, at least the rear wheel braking force generated by the rear wheel brake is decreased in response to the decrease in a rear wheel brake operation amount.
Patent EP-4081912-A1 (EP)
Inventor: AMADIEU OLIVIER
IPC: G06F16/957
Filed: 2020-11-24
Abstract: A method of optimizing transmission of requests for updated content from external data sources includes: storing a data object containing initial content received from at least one of the external data sources and associated with an expiry time; storing a set of optimization parameters; obtaining an instruction to request updated content corresponding to the data object; in response to obtaining the instruction, determining, based on the optimization parameters and the expiry time, whether to request updated content from the external data sources; when the determination is affirmative, transmitting at least one update request to at least one of the external data sources based on the initial content and the optimization parameters; and in response to transmitting the at least one update request, receiving and storing respective sets of updated content from the external data sources.
Patent EP-4031348-A1 (EP)
Inventor: WANG YAO
IPC: B29C45/33
Filed: 2020-10-21
Abstract: An injection molded slide actuator assembly which has a frame, a slide carrier and a slide track member. The injection molded slide actuator has an X, Y, and Z axis with the slide track member having at least one track slot extending along the y and the Z direction and said slide carrier having at least one cooperating outwardly extending side members for engaging the at least one track slot.
Patent EP-3974488-A1 (EP)
Inventor: KAKUTAKA KAIRI
IPC: C09J11/08
Filed: 2020-05-20
Abstract: There is provided an adhesive composition having both high adhesion force and stable adhesion performance. An adhesive composition comprising, per 100 parts by mass of a curable resin (A), 1 part by mass or more and 80 parts by mass or less of substantially spherical organic particles (B), wherein the adhesive composition is used in an application amount of 5 mg/cm<sup>2</sup> or more and 500 mg/cm<sup>2</sup> or less on an adherend.
Patent EP-3976767-A1 (EP)
Inventor: TAKEBE TAKANORI
IPC: C12N5/16
Filed: 2020-05-29
Abstract: Disclosed herein are compositions and methods for reprogramming induced pluripotent stem cells, such as from a primed to naïve state. Further disclosed herein are methods of making said reprogrammed induced pluripotent stem cells by contacting the stem cells with another population of stem cells.
Patent EP-4061828-A1 (EP)
Inventor: SCHÄBERLE TILL
IPC: C07K7/06
Filed: 2020-11-20
Abstract: The invention is concerning a medical preparation comprising bicyclic heptapeptides for use in vertebrates or humans suffering from an infection caused by Gramnegative bacteria like Pseudomonas aeruginosa, Klebsiella pneumoniae, Acineto bacter baumannii, Neisseria gonorrhoeae, Chlamydia trachomatis, Shigella sonnei, Salmonella enterica Typhimurium LT2, Enterobacter spp., Bifidobacterium longum, Bacteroides fragilis, Lactobacillus reuteri, Enterococcus spp., Yersinia pestis and numerous other Gram-negative bacteria.
Patent EP-3980881-A1 (EP)
Inventor: LEE JAE MIN
IPC: G06F3/048
Filed: 2020-06-05
Abstract: Systems and methods are disclosed for aligning a two-dimensional (2D) design image to a 2D projection image of a three-dimensional (3D) design model. One method comprises receiving a 2D design document, the 2D design document comprising a 2D design image, and receiving a 3D design file comprising a 3D design model, the 3D design model comprising one or more design elements. The method further comprises generating a 2D projection image based on the 3D design model, the 2D projection image comprising a representation of at least a portion of the one or more design elements, generating a projection barcode based on the 2D projection image, and generating a drawing barcode based on the 2D design image. The method further comprises aligning the 2D projection image and the 2D design image by comparing die projection barcode and the drawing barcode.
Patent EP-3973965-A1 (EP)
Inventor: SUN HONGBIN
IPC: A61P9/00
Filed: 2020-05-29
Abstract: The present invention discloses a medical use and a drug composition for pentacyclic triterpenoid saponin compounds, and particularly relates to a use of pentacyclic triterpenoid saponins represented by formulas (I)-(XVI) in preparing a drug for preventing or treating AMPK and/or ERRα-mediated diseases, including in preparing a drug for preventing or treating diseases, such as hepatic diseases, respiratory system diseases, metabolic disorders, autoimmune diseases, cardiovascular and cerebrovascular diseases, kidney diseases, central nervous system diseases or muscular dystrophy. The drug composition for preventing and treating the AMPK and/or ERRa-mediated diseases in the present invention contains compounds represented by formulas (I)-(XVI) or pharmaceutically acceptable salts or solvates thereof as active ingredients and pharmaceutically acceptable adjuvants.
Patent EP-4058029-A1 (EP)
Inventor: SCHOBEL ALEXANDER MARK
IPC: A61K47/00
Filed: 2020-11-13
Abstract: A method of administering diazepam with a multimodal delivery profile is described.
Patent EP-4073538-A1 (EP)
Title: Method, device, system for positioning acoustic wave signal source and vehicle
Inventor: BOHNENKAEMPER TIMO
IPC: G01S11/14
Filed: 2020-12-10
Abstract: The present disclosure relates to a method for positioning an acoustic wave signal source in a vehicle, which comprises: collecting at least two acoustic wave signals; calculating (102) a relative position of the acoustic wave signal source (20) relative to the vehicle (10) based on the at least two acoustic wave signals; obtaining (103) a position of the vehicle (10); and determining (104) positioning information of the acoustic wave signal source (20) based on the position of the vehicle (10) and the calculated relative position of the acoustic wave signal source (20) relative to the vehicle (10). Furthermore, the present disclosure relates to a device for positioning an acoustic wave signal source in a vehicle, a system for positioning an acoustic wave signal source in a vehicle, and a vehicle comprising such system.
Patent EP-4058460-A1 (EP)
Inventor: HUBER FLORIAN
IPC: C07K16/44
Filed: 2020-11-12
Abstract: L'invention concerne un complexe comprenant une substance antibiotique et un réactif de dérivation nucléophile, des compositions comprenant le complexe, des kits comprenant le complexe ou la composition, ainsi que des utilisations du complexe ou de la composition.
Patent EP-3990548-A1 (EP)
Title: Méthodes et systèmes de détection de maladie
Inventor: FAHAM MALEK
IPC: C08L71/12
Filed: 2020-06-24
Abstract: L'invention concerne des méthodes permettant de déterminer si un sujet est atteint d'une maladie ou est exposé à une maladie (par exemple, le cancer) à l'aide de molécules d'acide nucléique dérivées d'un échantillon biologique acellulaire du sujet.
Patent EP-3989811-A1 (EP)
Inventor: MOYER DANIEL V
IPC: H05K3/46
Filed: 2020-06-29
Abstract: Introduced here is an ingestible device comprising a capsule, a camera, an antenna, and a propulsion component. The camera can capture images of various in vivo environments as the ingestible device traverses the gastrointestinal tract, and these images can be wirelessly transmitted to an electronic device located outside of the living body. The images may be transmitted to the electronic device for review by an operator responsible for controlling the ingestible device.
Patent EP-3993029-A1 (EP)
Inventor: YEO SEUNG YONG
IPC: H01L25/075
Filed: 2020-04-22
Abstract: A light emitting module according to an exemplary embodiment of the present disclosure includes: a circuit board; and light emitting diode chips arranged in a plurality of regions on the circuit board, in which the light emitting diode chips are divided into a plurality of light emitting diode groups connected in series, the plurality of light emitting diode groups is connected in parallel to one another, and at least one of the light emitting diode chips in at least one of the plurality of light emitting diode groups is disposed in a region different from that of at least one other light emitting diode chip.
Patent EP-4076772-A1 (EP)
Title: Polyurea coating systems as sealants for the exterior of fuel tanks
Inventor: KRAEMER MICHAEL
IPC: B05D1/34
Filed: 2020-12-18
Abstract: The present invention relates to a 2K coating system consisting of two components (A) and (B) being separate from each other, wherein (A) comprises at least one constituent (a1) containing at least one aromatic moiety and bearing on average at least two primary and/or secondary amino groups, wherein (B) comprises at least one constituent (b1) containing at least one aromatic moiety and bearing on average at least two isocyanate groups, wherein each of (A) and (B) has a solid content of at least 95 wt.-%, based on the total weight of the respective component, and constituent (b1) present in component (B) bears carbodiimide and/or uretonimine units as well as at least one structural unit (I), a coating composition obtainable by mixing components (A) and (B) of the inventive coating system, a use of said coating composition as sealant, in particular for sealing the exterior of fuel tanks, a method of applying the coating composition to a substrate and in particular a method of sealing the exterior of fuel tanks, and a sealed substrate such as a sealed fuel tank obtainable by this method.
Patent EP-4081750-A1 (EP)
Title: Plant and process for storing and discharging thermal energy
Inventor: SPADACINI CLAUDIO
IPC: F01K3/12
Filed: 2020-12-21
Abstract: A plant for storing and discharging thermal energy comprises a first heat exchanger (2) coupled to a heat source (3), a second heat exchanger (4) coupled to a heat user (5), a fluid (F) configured to store thermal energy, a storage device (6) for the fluid (F), a circuit configured to couple the first heat exchanger (2), the second heat exchanger (4) and the storage device (6). The storage device (6) comprises N+B storage sections (13a, 13h) fluidly connected to each other, where N is equal to or greater than two and B is less than N; each of the N+B storage sections (13a,..., 13h) has a same containment volume (V). The fluid (F) occupies a volume substantially equal to N times the containment volume (V). A separation gas (G) is inserted in the storage device (6), is in contact with the fluid (F) and is configured to always keep separate a hot portion of the fluid from a cold portion of the same fluid.
Patent EP-4009030-A1 (EP)
Title: Sampling device and detection box
Inventor: SHANG TAO
IPC: G01N1/38
Filed: 2020-07-31
Abstract: A sampling device comprises a handle and a collector. The collector is connected to the handle. The collector has a capillary function and is able to automatically suction a liquid reagent or sample. The sampling device is able to suction a required amount of the reagent or sample quickly, conveniently and quantitatively. The sampling device can be product conveniently, and may achieve micro-quantitative sampling. The reagent is stored in the collector of the sampling device in the form of a dry powder, which may achieve the individual packaging of the detection reagent.
Patent EP-4026897-A1 (EP)
Inventor: INADA Ayaka
IPC: C12N11/02
Filed: 2020-09-02
Abstract: The present disclosure provides a method for producing a frozen body of a three-dimensional tissue aggregate of retinal pigment epithelial cells, the method including a step of preparing the three-dimensional tissue aggregate of the retinal pigment epithelial cells, and a step of subjecting the three-dimensional tissue aggregate of the retinal pigment epithelial cells to a freezing treatment at a predetermined freezing temperature set in advance using, as an index, the occurrence rate of a linear aggregate of dead cells in the three-dimensional tissue aggregate of the retinal pigment epithelial cells after thawing, thus obtaining the frozen body.
Patent EP-4027683-A1 (EP)
Inventor: SHIMODA TADAHIRO
IPC: H04W68/12
Filed: 2020-08-27
Abstract: A technology that enables prompt NW connection is provided. A communication system includes: a communication terminal; and a plurality of networks configured to perform radio communication with the communication terminal. The communication terminal determines whether or not there is paging causing collision among a plurality of pagings respectively transmitted to the communication terminal from the plurality of networks (ST1615). When the communication terminal detects the collision of the paging, the communication terminal notifies at least one of the plurality of networks that transmits the paging causing the collision of the paging about the collision of the paging (ST1629).
Patent EP-4028177-A1 (EP)
Inventor: GLASBEY TREVOR
IPC: A61B1/00
Filed: 2020-08-21
Abstract: L'invention concerne un applicateur de lubrifiant médical qui comprend : une tête de distribution conçue de façon à s'adapter à un récipient contenant un lubrifiant médical, la tête de distribution comprenant : (i) une buse ayant une ouverture d'évacuation à partir de laquelle le lubrifiant médical provenant du récipient est distribué ; (ii) un élément de guidage agencé par rapport à la buse de façon à fournir un contact de guidage avec une surface exposée d'un instrument médical sur lequel le lubrifiant médical distribué doit être appliqué, moyennant quoi, lors de l'utilisation, la buse, à l'aide de l'élément de guidage, est espacée de la surface exposée de l'instrument médical de façon à éviter tout contact avec ladite surface exposée, pendant que le lubrifiant médical est dirigé vers la surface exposée pour l'application dudit lubrifiant sur ladite surface exposée par l'intermédiaire de l'ouverture d'évacuation de la buse.
Patent EP-4032888-A1 (EP)
Title: Cyano-substituted cyclic hydrazine derivative and application thereof
Inventor: SHEN WANG
IPC: C07D471/14
Filed: 2020-06-11
Abstract: The present invention provides a cyano-substituted cyclic hydrazine derivative, comprising: a compound represented by the following structural formula or a stereoisomer, a geometric isomer, a tautomer, a racemate, a hydrate, a solvate, a metabolite and a pharmaceutically acceptable salt or a prodrug thereof. The compound is used for prevention, treatment or alleviation of autoimmune diseases or proliferative diseases in patients, and/or for inhibiting or modulating protein kinase activity.