baber/WOPTO huggingface dataset:
Patent CO-6241170-A2 (CO)
Title: Administracion de oligonucleotidos antisentido complementarios a la apolipoproteina b humana
Inventor: GERAY RICHARD
IPC: C12N15/113
Filed: 2009-10-22
Abstract: 1.- Un método que comprende administrar a un sujetouna composición farmacéutica que comprende unoligonucleótido antisentido complementario a un ácidonucléico que coditica apolipoproteína humana B-100, endonde la administración comprende una fase de inducción,en donde una dosis del oligonucleótido antisentido quevaria entre 100-300 mg es administrada una vez porsemana durante al menos 13 semanas, seguida por unafase de mantenimiento, en donde una dosis deloligonucleótido antisentido que varía entre 80-200 mg esadministrada una vez por semana o una vez cada dossemanas durante el tiempo que se requiera, sea efectivay/o tolerada.2.- El método de la reivindicación 1, en donde la dosisadministrada en la fase de inducción es una dosis de 100mg y la dosis administrada en la fase de mantenimiento esuna dosis de 200 mg administrada una vez por semana.3.- El método de la reivindicación 1, en donde la dosisadministrada en la fase de inducción es una dosis de 100mg y la dosis administrada en la fase de mantenimiento esuna dosis de 200 mg administrada una vez por semana, yen donde la tolerabilidad o la efectividad delolilgonucleótido antisentido se evalúan durante o al final delperiodo de inducción, o una porción del mismo una vez porsemana durante la fase de mantenimiento.4.- El método de la reivindicación 1, en donde la dosisadministrada en la fase de inducción es una dosis de 100mg y la dosis administrada en la fase de mantenimiento esuna dosis de 100 mg administrada una vez cada dossemanas, y en donde la tolerabilidad o la efectividad deloligonucleótido antisentido se evalúan durante o al final delperiodo de inducción, o una porción del mismo.5.- El método de la reivindicación 1, en donde la dosisadministrada en la fase de inducción es una dosis de 200mg y la dosis administrada en la fase de mantenimiento esuna dosis de 200 mg administrada una vez cada dossemanas, y en donde la tolerabilidad o la efectividad deloligonucleótido antisentido se evalúan durante o al final delperiodo de inducción, o una porción del mismo.6.- El método de la reivindicación 1, en donde la dosisadministrada en la fase de inducción es una dosis de 100mg a 200 mg y la dosis administrada en la fase demantenimiento es una dosis de 200 mg a 300 mg y esadministrada una vez por semana.7.- El método de la reivindicación 1, en donde dichaadministración parenteral comprende administraciónsubcutánea.
Patent CO-6341584-A2 (CO)
Title: Composiciones de catalizadores de metaloceno intermedio y sus productos polimericos.
Inventor: MCDANIEL MAX P
IPC: B01J31/22
Filed: 2011-01-13
Abstract: La presente invención describe nuevos compuestos de metaloceno híbridos que tienen un radical de metaloceno y un ligando que contiene un heteroátomo. De acuerdo con un aspecto de la presente invención, estos compuestos de metaloceno híbridos sin puente tienen la fórmula:en donde:M es Zr, Hf o Ti;X1 y X2 son independientemente un haluro o un grupo alifático, aromático o cíclico sustituido o insustituido o una combinación de los mismos;X3 es un es un grupo ciclopentadienilo, indenilo o fluorenilo sustituido o insustituido, cualesquiera sustituyentes en X3 son independientemente un átomo de hidrógeno o un grupo alifático, aromático o cíclico sustituido o insustituido o una combinación de los mismos;X4 es -O-RA, -NH-RA, PH-RA, -S-RA o -CRB=NRc,en donde:RA es un grupo arilo sustituido con un sustituyente alquenilo, cualesquiera sustituyentes en RA además del sustituyente alquenilo son independientemente un átomo de hidrógeno o un grupo alquilo, alquenilo o alcoxi sustituido o insustituido; y RB y RC son independientemente un átomo de hidrógeno o un grupo alifático, aromático o cíclico sustituido o insustituido o una combinación de los mismos.
Patent CO-6761358-A2 (CO)
Title: Boquillas de alimentación de reactor mejoradas
Inventor: SILVERMAN MICHAEL A
IPC: B01J4/00
Filed: 2013-07-02
Abstract: Se divulgan boquillas de alimentación de reactor mejoradas. De acuerdo con una realización, una boquilla de alimentación comprende una tubería interior encerrada en una tubería de escudo de calor exterior, un primer agujero circular fabricado en la tubería interior, el primer agujero circular tiene un primer diámetro y sirve como un agujero de descarga, un segundo agujero circular fabricado en la tubería de escudo de calor exterior, el segundo agujero circular tiene un segundo diámetro, donde el segundo diámetro es mayor que el primer diámetro; y una punta soldada para extender una vía de flujo en un ángulo decreciente, la punta soldada tiene una sección que se extiende en un ángulo predeterminado desde la tubería interior al agujero de descarga.
Patent CO-7101194-A2 (CO)
Title: Composicion a partir de extracto de hemocitos de langosta para la deteccion de lipopolisacaridos, peptidoglicanos y 1,3-beta-d-glucanos
Inventor: PERDOMO MORALES ROLANDO
IPC: C12Q1/37
Filed: 2014-07-25
Abstract: VER ANEXOS
Patent DD-225815-A2 (DD)
Title: Elektrischer schalter mit geradlinig bewegbarem betaetigungsteil
Inventor: HOFFMANN JUERGEN
IPC: H01H13/00
Filed: 1983-10-31
Abstract: Die Erfindung betrifft einen elektrischen Schalter mit geradlinig bewegbarem Betaetigungsteil nach Patent 211 424. Ziel und Aufgabe der Erfindung ist, die Vorteile des Hauptpatentes weiter zu erhoehen und insbesondere eine noch guenstigere, platzsparende Montagemoeglichkeit zu schaffen sowie die bisher notwendige Korrektion des Betaetigungsteiles zu vermeiden. Diese Aufgabe ist bei einem elektrischen Schalter nach dem Hauptpatent dadurch geloest, dass der die Kontakteinrichtung mit ihren Kontaktteilen und ihrem Federmechanismus aufnehmende Gehaeuseblock an der die Frontplatte beispielsweise eines Monitors naheliegenden Leiterplatte befestigt ist.
Patent EP-1096567-A2 (EP)
Inventor: TERUI MAKOTO
IPC: H01L23/24
Filed: 2000-03-22
Abstract: A ball grid array (BGA) package includes a substrate (20)
having first and second surfaces, and through holes (30) passing
through it. The package further includes a first semiconductor chip
(28) which is mounted on the first surface of the substrate (20); a
second semiconductor chip (36) which is mounted on the second
surface of the substrate (20); and solder balls (34) which are provided
on the first surface of the substrate (20) and are electrically
connected to the first semiconductor chip (28). The second
semiconductor chip (36) is electrically connected via the through
holes (30) to the solder balls (34).
Patent EP-1063608-A2 (EP)
Inventor: REID JAMES J
IPC: G06F3/0354
Filed: 2000-06-21
Abstract: In a manually movable computer mouse with a mouse movement
sensing system for providing mouse movement signals, and at least one user
finger operable control switch, for providing control signals for a graphic user
interface, the mouse has a boomerang shaped body ergonomically shaped to fit
and support the user's hand in a naturally relaxed curled hand position, with a
main body portion and a narrower neck portion extending at an angle of about 45
degrees to 90 degrees to the main body narrow enough to be interposeable
between the thumb and first finger, and with an integral mouse movement control
fin or tab extending above the mouse body and being thinly shaped to fit in the
relaxed space between the first and second fingers (and to also provide an
alternate pen-like grip between the thumb and first finger) to orient the mouse to
the users hand and move the mouse with user arm movements. An integral wrist
support may be provided extending from the wrist end of the mouse. The
movement sensing system is adjacent that same end.
Patent EP-1085427-A2 (EP)
Inventor: BAO JAY
IPC: H04L27/34
Filed: 2000-06-27
Abstract: An apparatus receives and demodulates digital signals encoded in multiple formats.
The apparatus includes multiple processor units and a memory embedded with the
processor units, and a cache connected to each of the processor units. The cache for
communicating between the plurality of processors. The embedded memory can
include data and instruction memory. The processor units and memory are
configured as a multi-mode receiver demodulator front-end capable of receiving
digitally modulated signals in multiple formats, and demodulating the signals in
real-time in response any one of the multiple formats.
Patent EP-1072456-A2 (EP)
Inventor: PLESTERNINGS FRANK
IPC: B60J7/185
Filed: 2000-07-20
Abstract: The pull-in and locking device is made so that the free end (B) of the closing hook (1) can be displaced relative to the hook rear end (A) and can turn in a casing. The guide lever (2) has one end (C) pivoted to the casing and the other end (D) able to turn on the hook in its central region. A drive lever (4) has one end (G) pivoted to the casing and a turning joint at its other end (H).
Patent EP-1085220-A2 (EP)
Inventor: STECK OTTO
IPC: F16B35/04
Filed: 2000-08-30
Abstract: The bolt anchor has a cylindrical metal bolt element (1), for insertion into a bore in a wall. A holder unit fixes an object to the bolt element. A thread (2) on the outside of the bolt element secures the bolt anchor into the concrete. An inner threaded blind bore (5) extends from the outer end face (4). A threaded bolt, which is narrower than the bolt element can be fitted in the inner bore and protruded from it. An Independent claim is included for a tool for inserting a bolt anchor.
Patent EP-1089149-A2 (EP)
Inventor: FOCKE HEINZ
IPC: A24C5/31
Filed: 2000-09-09
Abstract: The fault diagnosis method checks the product provided by the machine for providing a signal (46) when a product fault is indicated, with evaluation of the latter signal for determining the period interval of the faulty products, with indication of the faulty machine group (13,17,29) and/or tool (15,40). An Independent claim for a machine fault diagnosis device is also included.
Patent EP-1092455-A2 (EP)
Inventor: TANAKA TOSHIYUKI
IPC: A63C10/28
Filed: 2000-10-02
Abstract: A support for a snowboard boot binding (10) includes a support member having a
first support surface (100) extending on a first side of a support axis (x), wherein the
first support surface (100) is concave relative to the support axis (x), and wherein the
first support surface (100) extends less than 360° around the support axis (x). A second
support surface (104) is disposed on a second side of the support axis (x). The
first (100) and second (104) support surfaces are configured such that they are capable
of radially retaining a cleat engagement control shaft (108).
Patent EP-1112818-A2 (EP)
Inventor: HOGAN MICHAEL P
IPC: B25B23/157
Filed: 2000-12-20
Abstract: A torque apparatus for the installation and removal of threaded connecting devices that
employs a plurality of leaf spring elements engaging a plurality of asymmetrical drive teeth sides
to establish preset torque values in a hermetically sealed configuration or a variable range of
preset torque values in a second configuration. The preset torque values can be readily changed
in the second configuration by employing different quantities of leaf springs, differing leaf spring
designs, or varying the geometry of the rotor drive teeth. The leaf spring to rotor drive teeth
interface provides a slip mechanism to prevent over-torquing when torque values for the
installation of a threaded connecting type device is exceeded. While both torque wrench
configurations are sterilizable, the torque wrench that is capable of full disassembly for
sterilization and use thereafter in a sterilized environment, is reconfigurable for different torque
applications without calibration. The wrench can be primarily constructed as disposable device.
Patent EP-1031458-A2 (EP)
Inventor: CUNNINGHAM SPENCER D II
IPC: B60N2/68
Filed: 2000-02-21
Abstract: A vehicle seat (10) for use in a vehicle having a floor includes a safety belt
system(18) mounted to and carried by the vehicle seat (10), a lower seat structure (26)
mounted to the floor, a seat back frame (24), and a pivot assembly (44,46) connecting
the seatback frame (24) to the lower seat structure (26) such that the seatback frame
(24) may pivot with respect to the lower seat structure (26). The pivot assembly (44,
46) includes a bracket (48) connected to the lower seat structure (26), and a pivotable
connector member (50) connected to the seatback frame 924) and pivotally connected
to the bracket (48). The bracket (48) has first and second side portions (52,54) that
define an open bottom, and the first and second side portions (52,54) are connected to
the lower seat structure (26).
Patent EP-1041522-A2 (EP)
Inventor: STANNERS ANTHONY J
IPC: G06K9/00
Filed: 2000-03-21
Abstract: A self service terminal (10) including a human iris
identification system is described. The iris
identification system comprises a camera (30) for
recording an image of a human iris via a lens (32), a
processor (54) for processing the recorded image, and a
plurality of visual indicators (72,74,76 or 82,84,86)
associated with the lens (32) for directing a user's eye
towards the lens (32) of the camera (30), thereby
enabling the camera (30) to record a clear image of the
user's eye. A method of directing a user's eye towards a
lens (32) of a camera (30) used in a human iris
identification system is also described.
Patent EP-1068932-A2 (EP)
Inventor: MORRONEY WAYNE D
IPC: F15B15/20
Filed: 2000-07-14
Abstract: A valve and position control system (56) integrable with a clamp
having at least one clamp arm moveable between a clamped position and
a released position in response to movement of an actuator (60) between
first and second end limits of travel controlled by differential fluid
pressure in first and second chambers (22 and 58) of the actuator (60).
The system (56) allows selective setting of at least one of the clamped
position and the released position at an actuator position between the first
and second end limits of travel of the actuator (60). The system (56)
selectively controls the speed of actuator movement as the actuator (60)
moves between the first and second end limits of travel. Preferably, the
system (56) also selectively controls the speed of actuator movement as
the actuator (60) approaches at least one of the first and second end
limits of travel to provide a soft touch clamp action. The system (56)
selectively adjusts pressurized fluid within the first and second chambers
(22 and 58) independently of one another.
Patent EP-1102189-A2 (EP)
Inventor: SATOSHI ITO
IPC: G06F17/30
Filed: 2000-11-22
Abstract: In an electronic catalog maintenance system using the
dictionary data given in a form of a tree structure formed
by identifiers for uniquely identifying classes classifying
products and attributes of the products, the dictionary
data are edited by making changes including standard
changes defined by a prescribed standard and out-of-standard
changes not defined by the prescribed standard,
and an identifier change data indicating the status of each
change made by the editing and updates of identifiers to be
made in the dictionary data is generated. Then. a new
identifier of each class or attribute created by an out-of-standard
change is issued and an old identifier of each
class or attribute deleted by an out-of-standard change is
retired according to the identifier change data, while
storing the identifier change data in an identifier change
database.
Patent EP-1070467-A2 (EP)
Inventor: GUERET JEAN-LOUIS
IPC: A45D40/18
Filed: 2000-07-21
Abstract: The invention concerns a comb (1) for applying a product on keratinous fibres, comprising an arrangement of teeth (2a, 3a) foe applying said product. The invention is characterised in that said arrangement of teeth is obtained by assembling at least two separate parts (2, 3). The invention also concerns an application set equipped with such a comb (1), and its use for applying make-up on eyelashes or eyebrows.
Patent EP-1220714-A2 (EP)
Inventor: FROM PETER SENDAL
IPC: B01F3/08
Filed: 2000-03-02
Abstract: L'invention concerne un procédé et un appareil permettant une opération d'homogénéisation en continu ou d'émulsification d'un liquide (I, II) dans une chambre à ultrasons (1) dotée de feuilles (2) ou de plaques de guidage (2), placées dans le bord ou la paroi externe de la chambre (1), mais aussi dans la zone du dessus. Après faire subir au liquide un traitement mécanique cinématique, notamment par brassage (3) et après son écoulement en continu guidé au-delà de la surface des transducteurs ultrasonores (5), ces derniers (5) sont commandés selon un ordre de succession alors qu'au moins un transducteur est au repos.
Patent EP-1159455-A2 (EP)
Inventor: MCGILL UNIVERSITY
IPC: C12Q1/68
Filed: 2000-02-28
Abstract: Provided herein is a heretofore unknown isolated nucleic acid molecule which encodes human methylenetetrahydrofolate reductase, along with an amino acid sequence of methylenetetrahydrofolate reductase, and a cDNA probe for human methylenetetrahydrofolate reductase. Also provided are a molecule description of mutations in humans resulting in a phenotype having reduced levels of methylenetetrahydrofolate reductase, and methods of diagnosing methylenetetrahydrofolate reductase deficiency in a human.
Patent EP-1165342-A2 (EP)
Title: Automobile seat
Inventor: LIEBETRAU MATTHIAS
IPC: B60N2/08
Filed: 2000-03-15
Abstract: The invention relates to a vehicle seat comprising the following: a seat frame; a backrest which is pivotably mounted on said seat frame and can be folded towards the seat surface; a longitudinal guide (1, 2) with which the seat frame can be moved in the longitudinal direction of the seat in order to adjust the longitudinal seat position; a fixing device (20) for fixing the seat frame in a previously selected longitudinal seat position; an operating element (20b) for unlocking the fixing device (20); a coupling mechanism (9, 21, 21a, 21b) which unlocks the fixing device (20) when the backrest is folded towards the seat surface; a memory device (4, 5, 7) by which means the seat frame can be automatically stopped in a predetermined longitudinal seat position (memory position); regulating means(5) for the memory device, with which the memory position can be regulated in the longitudinal direction of the seat (L); a locking device (4, 7) for the memory device, for locking a selected memory position and switching means (6) with which the locking device (4, 7) can be unlocked in order to regulate the memory position. The coupling mechanism (9, 21, 21a, 21b) only acts on the operating element (20b) to unlock the fixing device (20) for as long as the backrest is folded forward and the seat frame can be stopped by the fixing device (20) when the backrest is not folded forward.
Patent EP-1192119-A2 (EP)
Inventor: EBNER JERRY R
IPC: C07C29/147
Filed: 2000-06-29
Abstract: 3,3-Dimethylbutanal is prepared from 3,3-dimethylbutanol. Intermediate 3,3-dimethylbutanol is obtained by reacting ethylene, isopropylene and a mineral acid to produce a 3,3-dimethylbutyl ester which is hydrolyzed to the alcohol. The hydrolysis step is effectively carried out by reactive distillation. Alternatively, 3,3-dimethylbutanal is prepared from 3,3-dimethylbutanol obtained by reduction of the corresponding carboxylic acid or 1,2-epoxy-3,3-dimethylbutane, or by hydrolysis of 1-halo-3,3-dimethylbutane. Fixed bed gas phase and stirred tank liquid phase processes are provided for converting 3,3-dimethylbutanol to 3,3-dimethylbutanal by catalytic dehydrogenation.
Patent EP-1145069-A2 (EP)
Inventor: SYMANOWSKI CHRISTFRIED
IPC: G02B26/08
Filed: 2000-09-29
Abstract: Eine Anordnung, bei der von einer Lichtquelle (44) aus Licht mittels einer Beleuchtungsoptik (12) auf eine Fläche (25) gerichtet wird, auf der ein Bild einstellbar ist, das mittels einer Projektionsoptik (4) erfassbar ist, ist dadurch gekennzeichnet, dass die Beleuchtungsoptik (12) eine der Lichtquelle (44) nachgeschaltete Optikeinrichtung (28) und zwischen der Fläche (25) und der Optikeinrichtung (28) angeordnetes Prisma (10), mittels dem das von der Optikeinrichtung (28) kommende Licht ohne Reflexion umgelenkt wird, aufweist.
Patent EP-1259914-A2 (EP)
Inventor: GAUER GERRY
IPC: G06Q40/00
Filed: 2000-12-01
Abstract: A system and method for processing a mortgage application is disclosed. The system comprises a database comprising a plurality of records wherein information related to properties are stored. The records have property attributes stored therein. A computer program is adopted to provide a selection screen for selecting a property record from the database. The computer program is further adopted to present a loan application data entry screen having at least one data entry field. The computer program is further adopted to automatically enter one of the property attributes as an initial entry into one of the data entry fields. The computer program is further adopted to receive loan application data and credit data related to processing a loan from the data entry screen. The computer program is further adopted to process the loan application data, thereby creating a pre-approval status. The computer program is further adopted to forward the pre-approval status to at least one lender, who may then contact the applicant. The computer program may utilize an automated underwriting program to perform the underwriting function for loan application processing for pre-approval.
Patent EP-1238274-A2 (EP)
Inventor: HAAR HANS-PETER
IPC: G01N33/48
Filed: 2000-10-26
Abstract: Test element analysis system ( 1 ) for the analytical investigation of a sample ( 8 ), in particular of a body liquid, of human beings or of animals, comprising test elements ( 3 ) with a test zone ( 7 ), to be brought in contact with the sample to be investigated for the purpose of performing an analysis, in order to measure a measurement quantity characteristic for the analysis, and an evaluation instrument ( 2 ) with a test element holder ( 5 ) for positioning a test element ( 3 ) in a measuring position in order to perform a measurement, and a measurement and evaluation electronics ( 15 ) for measuring the characteristic change and for determining a result of the analysis, based on the result of the measurement. In order to provide increased measuring accuracy by improved temperature compensation, it is proposed, in the scope of the invention, that the evaluation instrument ( 2 ) for the determination of the temperature prevailing in the test zone ( 7 ) of the test element ( 3 ) comprises an infrared detector ( 20 ).
Patent EP-1243089-A2 (EP)
Inventor: HIPP IMRE
IPC: H04L25/06
Filed: 2000-10-31
Abstract: Mit dieser Schaltungsanordnung und dem dazugehörigen Verfahren wird eine universelle Referenztaktschnittstelle für beliebige Synchronisationsquellen gebildet, wobei Abgleichvorgänge und Pegelanpassungen bei Entscheidungsschwellen adaptiv erfolgen.
Patent EP-1250378-A2 (EP)
Inventor: KLEMM ELISABETH
IPC: C08G75/045
Filed: 2000-12-06
Abstract: L'invention concerne une matière pour réaliser des revêtements et des collages, à base de polymères à motifs structuraux thioéther, ainsi qu'un procédé de production correspondant. En faisant varier la structure des composants de départ et/ou leur rapports molaires ainsi que les paramètres du photodurcissement ou du durcissement thermique, il est possible de faire varier les propriétés mécaniques des polymères selon l'invention sur une plage allant de dur à souple-élastique. Ces polymères peuvent être utilisés de multiples façons dans des revêtements transparents, protecteurs et décoratifs sur du verre, des matières plastiques et des métaux, ainsi que dans des collages. Pour produire ces polymères, on fait réagir par voie photochimique ou thermique (1) un composant oléfinique, (2) un composant thiol et (3) un prépolymère fonctionnalisé par un thiol. Ce dernier est produit au cours d'une étape de réaction précédente, par réaction de dithiols avec des diisocyanates et par catalyse basique.