baber/WOPTO huggingface dataset:
Patent CS-216529-B2 (CS)
Title: Method of making the 3-substituted hexahydropyridimo /1,2-a/azeoins
Inventor: KOEKOESI JOZSEF
IPC: C07D487/04
Filed: 1980-05-08
Abstract: A process for the preparation of pyrimido[1,2-a]azepines of the general formulae I   <IMAGE>  and mixtures and pharmaceutically suitable salts wherein  R is hydrogen or lower alkyl, R<1> is lower alkyl, phenyl, carboxyl, lower alkoxycarbonyl, nitrile, carbamoyl or carbohydrazido,  R<2> is hydrogen or lower alkyl  comprises reacting a compound of the formula III   <IMAGE> wherein R is defined as above with a compound of the formula IV   <IMAGE> wherein R<2> is as defined above,  R<3> lower alkyl, phenyl, lower alkoxycarbonyl, nitrile,  R<4> is hydrogen or lower alkyl R<5> is lower alkyl and optionally transforming the initial product(s). Most of the compounds of general formulae I and II are novel. The compounds are of interest in the treatment of angina.
Patent CS-268522-B2 (CS)
Title: Parting material for thin-layer chromatography
Inventor: HAUCK HEINZ E DR
IPC: B01J20/32
Filed: 1985-07-25
Abstract: Die Erfindung betrifft ein neues Trennmaterial für die Dünnschichtchromatographie auf Basis von mit Sorptionsmitteln beschichteten Trägermaterialien, bestehend im wesentlichen aus einer nach der Beschichtung durch Silanisierungsmittel oberflächenmodifizierten Kieselgelschicht, das dadurch gekennzeichnet ist, daß sich der Bedeckungsgrad definiert und steuerbar einstellen läßt von 0,15 bis 0,8 µmol/m 2  bei reversed-phase Materialien und 1.2 bis 2,5 µmol/m 2  bei hydrophilen Materialien, sowie ein Verfahren zur Herstellung dieser Trennmaterialien.
Patent CS-241122-B2 (CS)
Title: Method of ergoline derivatives production
Inventor: SAUER GERHARD
IPC: C07D457/12
Filed: 1982-09-03
Abstract: A process for preparing an ergoline of the formula  <IMAGE>  wherein C9----C10 is a CC single or double bond, R1 is hydrogen or CONR2, R being hydrogen, methyl, or ethyl, and wherein NR' is in the  alpha - or  beta - position, R2 is lower alkyl of up to 3 carbon atoms, and the salts thereof, comprises treating the corresponding ergolinyl carboxylic acid amide with lead(IV) acetate in an aprotic polar solvent; reacting the intermediarily formed corresponding isocyanate with water or with a reactive amine of up to 4 carbon atoms, (e.g. a mono- or dialkylamine of up to 4-C atoms); and, optionally, treating the resultant product with an acid to form the corresponding salt.
Patent CS-226037-B2 (CS)
Title: Method of preparing 2-amino-3-carbethoxyamino(6-p-fluorobenzylamino)pyridine-maleate
Inventor: VON BEBENBURG WALTER DR
IPC: C07D213/76
Filed: 1981-09-11
Abstract: There is prepared 2-amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)-pyridine-maleate of the formula   <IMAGE>   The compound has antiphlogistic and analgesic properties in the same manner as the known hydrochloride salt. In contrast to the hydrochloride 2-amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)-pyridine-maleate can be produced without a disturbing blue coloration. This maleate generally is formed from a mixture of two crystal modifications A and B, whereby there is especial advantageous in regard to isolation as well as the galenical preparations a mixture entriched in modification A (60 to 90% modification A).
Patent CS-198114-B2 (CS)
Title: Control valve for the hydraulic system
Inventor: RIDDOCH HENRY J
IPC: F15B13/04
Filed: 1972-11-10
Abstract: 1389020 Valves; antiskid systems GIRLING Ltd 27 Oct 1972 [12 Nov 1971] 52568/71 Headings F2V and F2F  A pressure-responsive control valve assembly, which is usable in an hydraulic braking system, has a ball valve member 33 operative to control flow between an inlet 35 and either one of two outlets 36 and 38. The valve member is urged, by the net force of opposed springs 13, 28, to engage a seating 16 thereby closing off outlet 36. Should the pressure of the flow then passing to outlet 38 rise above a predetermined value, then such pressure is operative to move actuator piston 26 against the force of spring 28 acting thereon until valve member 33 is caused, by spring 13, to engage seating 32 thereby to close outlet 38. A fall in pressure within the last mentioned outlet results in the system returning to the first state wherein outlet 36 is closed. When used in braking system, high pressure fluid is supplied to the wheel brake directly from a source connected to inlet 35 whilst outlet feeds an anti-skid system.
Patent CS-250675-B2 (CS)
Title: Driving mechanism for swinging trough
Inventor: MAILLET PIERRE
IPC: C21B7/20
Filed: 1984-11-05
Abstract: An apparatus for driving an oscillating spout capable of pivoting about two orthogonal axes under the action of a pivoting control arm having the same degrees of liberties as the spout is presented. The driving apparatus includes a control mechanism which directs the control arm to perform the movement required by the spout and a transmission device which acts to transmit the control arm movement to the spout to reproduce it as spout movement, and vice versa. The apparatus further includes a rotary internal housing supported on a support frame via a bearing member and enclosed by an outer housing or cowl. The rotary housing is associated with a toothed rim which is actuated by a first motor fixed to or adjacent to the support frame. A control mechanism is also provided which includes a driving rod which is coaxial with the rotary internal housing and which is capable of sliding in the axial direction. The control mechanism is associated with a second motor which is also adjacent to or fixed to the support frame. A pivotal connecting means consisting of a central body and two diametrically opposed pivots is mounted on the lower end of the driving rod via one or more bearings in such a way so as to be freely rotatable in relation to the rod (and in conjunction with the rotary housing) but integral therewith with regard to vertical or axial movement. The pivotal connecting means is associated with the rotary housing such that a high rate of rotation may be transferred thereto.
Patent JP-H028957-B2 (JP)
IPC: F01M1/00
Filed: 1983-01-20
Abstract: PURPOSE:To reduce an amount of oil used for flushing by supplying said oil stored in a lubricating oil clearing tank from a lubricating oil replenishing line directly to a lubricating oil service line. CONSTITUTION:Since flushing oil is circulated by the use of temporary pipings 20a, 20b, 20c without passing through the main engine 1, a reduction gear 2, subtanks 1a, 2a and a gravity tank 16, far smaller amount of the flushing oil can be used economically and advantageously compared with that in the conventional flushing method of circulating the flushing oil through the main engine 1, the reduction gear 2 and the subtanks 1a, 2b. Further, these tanks are not plluted by flushing and thus the interior of the tanks does not need to be cleaned again after flushing and flushing period can be shortened.
Patent JP-2703732-B2 (JP)
IPC: G03F7/027
Filed: 1995-01-24
Granted: 1998-01-26
Abstract: Waterborne photoimageable compsn. comprises: (a) 30-80 wt.% of a latex binder polymer including carboxylic acid cpds. giving an acid number of 50-250; (b) 15-50 wt.% of a fraction of alpha, beta-ethylenically unsatd. monomers; (c) 0.1-25 wt.% photoinitiator; (d) 1-40 wt.% of a neutralising base and/or polyether polyurethane associate thickener in amt. to stabilise emulsion of binder; and (e) 0.5-3.0 wt.% of a surfactant of a fluoroaliphatic oxyethylene adduct of formula (I). CF3-(CF2)n-Y-Xm-Z (I); n=0-20; Y = SO2-N (1-10C) alkyl; X = CH2-CH2-O or CH(CH3)-CH2-O; m=0-20; and Z= CH2-CH2-OH or CH(CH3)-CH2OH. Also claimed is a support sheet and layer of the compsn. above forming a dry film.
Patent JP-H0479737-B2 (JP)
IPC: B29C65/52
Filed: 1985-01-22
Abstract: PURPOSE:To make divided patterns adhere to each other without causing poor adhesion or a squeeze-out of adhesive and to mass-produce an investment casting pattern, by automatically coating an adhesive on the adhering surface of at least one side of divided patterns after setting the patterns on a pair of evacuat ing molds respectively, and sucking the patterns to bring them into tight contact with the molds, and moving the molds to the prescribed positions to join the patterns together. CONSTITUTION:An evacuating mold 4a, on which a divided pattern 1a coated with an adhesive is set is moved to the previously set position, and an evacuating mold 4b, on which a divided pattern 1b is set, is lowered by a cylinder 5, to make the adhering surfaces of patterns 1a, 1b coincide with each other, thereby finishing the adhering operation. Next, after releasing the evacuations of molds 4a, 4b, an investment casting pattern 1 is easily released by feeding air to chamber parts from pressurized air pipes.
Patent AU-760847-B2 (AU)
Title: Debiting device for deducting tolls
Inventor: BARKER RONALD
IPC: G07B15/00
Filed: 1999-08-06
Granted: 2003-05-22
Abstract: The invention relates to a debiting device which is arranged in a vehicle and which is provided for deducting tolls. Said tolls are to be paid for the utilization of distances of a road network which require the payment of a toll. The inventive device is comprised of device modules which are permanently installed in the vehicle. The device modules consist of a vehicle box (1), an external communications module (2), and a holding module (3). The device modules also include a mobile electronic toll device (4) which can be inserted into said holding module (3) and which can be easily removed again from the same.
Patent AU-654172-B2 (AU)
Title: A device for taking aseptic samples of products
Inventor: HUGELSHOFER WILLY
IPC: G01N1/10
Filed: 1992-03-23
Granted: 1994-10-27
Abstract: The device comprises a valve (4) for drawing off products, a vapour and sterile-air intake pipe (20), and a product-sampling pipe (23), in which device the drawing-off valve includes a blocking cone (7) bearing, in the closed state, on a valve seat (6), the plane of contact of the said cone with the said seat being situated virtually at the level of the surface of the enclosure, the vapour intake pipe ends directly on the head space of the valve, and the product-sampling pipe is in the extension of the vapour intake pipe. <IMAGE>
Patent AU-621818-B2 (AU)
Title: Electrode sensors, sensor cartridges and portable miniaturised analytical instruments
Inventor: GURUSWAMY VINODHINI
IPC: G01N27/26
Filed: 1988-01-29
Granted: 1992-03-26
Abstract: A cartridge for accurate reproduceful analytical solution evaluation is described. The cartridge includes sensors in an array within a test chamber. The number of sensors is one more than the number of substances to be measured. The cartridge is miniaturised and receivable within a compact instrument adapted for field use.
Patent AU-655810-B2 (AU)
Title: Surgical forceps
Inventor: WEBER ROBERT M
IPC: A61B17/32
Filed: 1992-04-24
Granted: 1995-01-12
Abstract: A surgical forceps (10) particularly useful in least invasive surgery includes an elongate probe formed of an outer tubular member (12) and an inner member (18) movable in the outer probe member, stationary and movable jaws (24,26) coupled with the distal ends, respectively, of the outer and inner probe members, and a handle (150) squeezable to move the movable jaw relative to the stationary jaw to rearwardly or forwardly cut tissue or to grasp tissue. A force diverting mechanism (166,172) is responsive to the force applied to the handle exceeding a predetermined force to provide the surgeon with an indication of the excessive force and protects the jaw components at the distal end of the surgical forceps. A suction passage is formed in the forceps for aspirating cut tissue and assisting the positioning of tissue between the jaws, and suction can be produced continuously or controlled via the handle. The handle includes locking and latching mechanisms (184,178) to hold the jaws in a closed position.
Patent AU-665753-B2 (AU)
Title: Improved method and apparatus for incrementally stretching a zero strain stretch laminate web to impart elasticity thereto
Inventor: WEBER GERALD MARTIN
IPC: A61F13/496
Filed: 1992-01-28
Granted: 1996-01-18
Abstract: An improved method and apparatus for incrementally stretching "zero strain" stretch laminate webs to impart elasticity thereto in the direction of initial stretching, at least up to the point of initial stretching. The "zero strain" stretch laminate material is formed of at least two plies of material which are either intermittently or substantially continuously secured to one another along at least a portion of their coextensive surfaces while in a substantially untensioned ("zero strain") condition. One of the plies is stretchable and elastomeric, while the second ply is elongatable, but not necessarily elastomeric. The second ply will, upon stretching of the laminate, be at least to a degree permanently elongated so that, upon release of the applied tensile forces, it will not return to its original undistorted configuration. This results in z-direction bulking of the laminate web when the applied tension is released as well as subsequent elastic extensibility in the direction of initial stretching, at least up to the point of initial stretching. In a particularly preferred embodiment of the present invention the opposed peripheral edge portions of the laminate web to be incrementally stretched are subjected to restraint to substantially prevent inwardly directed slippage or contraction thereof in a direction parallel to the direction of stretching. This maximizes the effectiveness of the incremental web stretching operation by forcing the "zero strain" stretch laminate web to undergo the fullest possible degree of elongation during the incremental stretching operation.
Patent AU-596311-B2 (AU)
Title: Method for excavating hole and apparatus therefor
Inventor: AKESAKA TOSHIO
IPC: E02F5/20
Filed: 1988-06-15
Granted: 1990-04-26
Abstract: A method for excavating a hole and an apparatus therefor are suitable for the operation of excavating a hole used for laying a lateral sewer or mounting pipe, which extends from a main sewer pipe (10) toward the ground surface, on the main sewer pipe. The method comprises the step of rotating a rod (12) about its axis in a space provided in the ground (72) while advancing the rod in the direction of penetrating a wall member (10) defining the space, and the step of utilizing the advanced rod for a guide while excavating a hole in the ground from the tip side of the rod toward the space. The apparatus embodying the method described above comprises a rod propelling machine (14) disposed in a space provided in the ground (72) and for rotating a rod (12) about its axis while advancing the rod and an excavating machine (74) utilizing the advanced rod for a guide and for excavating a hole in the ground from the tip side of the rod toward the space, wherein the rod propelling machine (14) includes operating means (21) for rotating the rod about its axis while advancing the rod and means (59) placed in front of the operating means and for guiding the rod in the direction of penetrating a wall member defining the space. Therefore, the hole is easily accurately excavated even in a spot incapable of being excavated by a driving method.
Patent AU-615450-B2 (AU)
Title: Novel fibrinolytic enzymes
Inventor: POHL GUNNAR
IPC: C12N9/72
Filed: 1988-06-17
Granted: 1991-10-03
Abstract: A fibrinolytically active plasminogen activator of the tissue type, wherein the growth factor (G) domain has been deleted, and wherein also the K1 domain has been deleted and additionally has been modified in one or more of the following sites or region: the sites of amino acid residues 177, 184, 277 and 448 and the F domain, the F domain modification if present being a deletion of part or all of said domain; DNA-sequence comprising a nucleotide sequence coding for said plasminogen activator; expression vector which in a transformed host cell can express said DNA-sequence;      host cell transformed using such vector; pharmaceutical composition comprising the fibrinolytically active plasminogen activator;      plasminogen activator for use in treating thrombotic disease; a process for the manufacture of such fibrinolytically active plasminogen activator;      a process for the treatment of thrombotic disorder; and a process of localizing thrombi while using such plasminogen activator.
Patent AU-692845-B2 (AU)
Title: Large pore synthetic polymer membranes
Inventor: DITTER JEROME
IPC: B01D71/68
Filed: 1995-03-03
Granted: 1998-06-18
Abstract: Highly asymmetric polymeric membranes with large pores which yield bubble points in the range of 0.5 to 25 psid and superior flow characteristics. The membranes can be cast from both metastable dispersions and from homogenous casting formulations. The technique of synthesis involves exposure of the cast membrane to humid air to create large surface pores on the exposed side.
Patent AU-777334-B2 (AU)
Title: Bacterial cell component-unresponsive model mouse
Inventor: AKIRA SHIZUO
IPC: C07K14/705
Filed: 2000-01-13
Granted: 2004-10-14
Abstract: A knockout mouse which is unresponsive to peptidoglycan, a lipoprotein/lipopeptide and the like, and is useful for elucidating the contribution of individual members of the TLR family to a signaling stimulated with bacterial cell components in vivo, in particular, the role of TLR2 and MyD88 in vivo. A bacterial cell component-unresponsive knockout mouse is generated by a process comprising the steps of: a targeting vector is constructed by replacing a whole or a part of a gene fragment of an exon region containing a cytoplasmic region of TLR2 or MyD88 gene and the like with a plasmid having a poly A signal and a marker gene; the targeting vector is introduced into an embryonic stem cell; the targeting embryonic stem cell having a homologously recombined TLR2 or MyD88 gene is microinjected into the blastocyst of a mouse and the blastocyst is put back into the uterus of a recipient mouse.
Patent AU-610918-B2 (AU)
Title: Metal surface refinement using dense alumina-based media
Inventor: MICHAUD MARK D
IPC: C23F3/00
Filed: 1988-08-03
Granted: 1991-05-30
Abstract: The invention provides a physicochemical process for refining relatively rough metal surfaces to a condition of high smoothness and brightness, in relatively brief periods of time, which is characterized by the use of a non-abrasive, high-density burnishing media. The process can be carried out in one step and with minimal production of media fines, thus affording economic and environmental advantages.
Patent AU-661328-B2 (AU)
Title: Novel microorganisms discovered through unique process
Inventor: HAYGOOD ROBERT A
IPC: C12N1/20
Filed: 1992-08-18
Granted: 1995-07-20
Abstract: The subject invention pertains to novel microorganisms useful for the control of unwanted grasses and other weeds. The microorganisms of the subject invention are discovered through a unique process which involves isolating plant pathogens from asymptomatic plants.
Patent AU-610281-B2 (AU)
Title: Solid-phase non-separation enzyme assay
Inventor: KHANNA PYARE
IPC: C12Q1/34
Filed: 1988-09-19
Granted: 1991-05-16
Abstract: Novel assays employing enzyme fragments which complex to form an active enzyme are provided. The reagents involved are a member of a specific binding pair bound to a solid surface, a first enzyme fragment conjugated to a member of a specific binding pair complementary or cross-reactive in relation to the analyte or antianalyte and a second enzyme fragment which binds to the conjugate to form an active enzyme, where the first enzyme fragment conjugate may be present in up to substantial excess to ensure at least substantially complete binding of all of the analyte. By distributing the conjugate between the solid surface and the medium in relation to the amount of analyte present, the enzyme activity may be determined in relation to the amount of analyte present.
Patent AU-604584-B2 (AU)
Title: Method for introducing and bonding gas into water, apparatus for carrying out the method and water produced by the method
Inventor: KOLTA PETER
IPC: A01G7/00
Filed: 1988-10-21
Granted: 1990-12-20
Abstract: A method for introducing gas like oxygen, air or carbon dioxide into water, in which a water flow enriched in the gas is passed through a reaction chamber so that the flow rotates around and moves along the longitudinal axis, a sudden pressure minimum is provided in a section of this axis where gas comprised in the flow gets collected and mixed with vapor, the pressure is increased after the minimum, whereby gas is swallowed by water so that gas molecules get bound to water molecules. The apparatus for carrying out the method comprises a closed recirculating path with the reaction chamber (15), the flow is maintained by a pump (14), and the gas is introduced in the water either by a vortex stream or by a water jet pump. The so obtained water comprises the gas in stable and bound state in a concentration exceeding normal saturation. The dielectric constant and certain physical parameters of such water differ from those of pure water.
Patent AU-560713-B2 (AU)
Title: Dental porcelain containing polyurethane
Inventor: MARTIN BRIAN
IPC: A61K6/884
Filed: 1984-04-10
Granted: 1987-04-16
Abstract: An opaque porcelain paste comprising an opaque porcelain powder mixed with an aqueous colloidal dispersion of a urethane polymer. The paste can be applied as the first layer to a dental coping, and does not need to be fired prior to the addition of the body porcelain layers.
Patent AU-767509-B2 (AU)
Title: Method for deprotecting oligonucleotides
Inventor: BHAN ANILA
IPC: C07H/
Filed: 2000-02-05
Granted: 2003-11-13
Abstract: A method for purifying an oligonucleotide that comprises providing an oligonucleotide attached to a substrate, wherein the oligonucleotide contains phosphate protecting groups; contacting the oligonucleotide with a reagent, e.g., an organic amine, that cleaves the phosphate protecting groups from the oligonucleotide without detaching the oligonucleotide from the substrate; isolating the oligonucleotide attached to the substrate from the cleaved phosphate protecting groups; and cleaving the oligonucleotide from the substrate. This method provides crude oligonucleotide mixtures that are easier to purify and from which the desired full-length oligonucleotide product can be isolated in higher yields.
Patent AU-695234-B2 (AU)
Title: Amino acid-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent and a medicament containing them
Inventor: KLEEMANN HEINZ-WERNER
IPC: C07C279/22
Filed: 1995-09-07
Granted: 1998-08-06
Abstract: Benzoyl guanine derivs. of formula(I) and their salts are new. One of the substits. R1-R3 = Y-Ph-Ä(CH2)k-CHR7-CO-R8Ü; and the others = 1-8C alkyl, 2-8C alkenyl, (CH2)mR14, SO2NHC(=Y')NR18R19, H, halo, CN, Z(CH2)p-CqF2q+1, SOuR22, CONR23R24, COR25, SO2NR26R27, OR35 or NR35R36; Ph = phenylene (opt. mono- or di-substd. by Fl, Cl, CF3, Me, OH, OMe or NR37R38); R37, R38 = H or Me; Y = a bond, O, S or NR9; R9 = H or 1-4C alkyl; R7 = OR10 or NR10R11; R10 = H 1-8C alkyl, 1-8C alkanoyl, 1-8C alkoxycarbonyl, benzyl, or benzyloxycarbonyl; R11 = as R10 or trityl; R8 = OR12 or NR12R13; R12, R13 = H, 1-8C alkyl or benzyl; R14 = 3-8C cycloalkyl or phenyl (both opt. substd. by 1-3 F, Cl, CF3, Me, OMe, or NR15R16); R15, R16 = H or Me; Y' = O, S or NR20; R18, R19 = H, 1-8C alkyl, 3-6C alkenyl or (CH2)tR21; or R18+R19 = A; R21 = 5-7C cycloalkyl or phenyl, (both opt. mono- to tri-substd. by F, Cl, OMe or 1-4C alkyl); R20 = as R18 or amidine; Z = a bond, O, S or NR28; R22 = 1-8C alkyl, 3-6C alkenyl, (CH2)nR29 or CF3; R23, R25, R26 = as R22 or H; R24, R27 = H or 1-4C alkyl; or R23+R24, R26+R27 = A; A = (CH2)4 or (CH2)5 (both opt. having a CH2 replaced by O, S, NH, NMe or N-benzyl; R28 = H or 1-3C alkyl; R29 = 3-7C cycloalkyl or phenyl (both opt. substd. by 1-3 F, Cl, CF3, Me, OMe or NR30R31; R30, R31 = H or 1-4C alkyl; R35, R36 = H or 1-6C alkyl; or R35+R36 = (CH2)y (opt. having a CH2 gp. replaced by O, S, NH, NMe or N-benzyl); R4, R5 = H, 1-4C alkyl, F, Cl, OR32, NR33R34 or CrF2r+1; R32-R34 = H or 1-3C alkyl; k, n, t = 0-4; m, u, p = 0-2; q = 1-6; r = 1-4; and y = 4-7.