baber/WOPTO huggingface dataset:
Patent CA-3137268-A1 (CA)
Inventor: BUDEL TRISTRAM
IPC: B22F3/105
Filed: 2020-02-28
Abstract: La présente invention concerne une machine de fabrication additive 3D et une méthode de fabrication additive pour fabriquer des objets couche par couche, et est destinée à éviter la nécessité d'un prisme rotatif. Des machines selon la présente invention peuvent remplir des espaces dans n'importe quelle couche entre des trajets générés par des points d'éclairage voisins d'un réseau par balayage de trajets ultérieurs entre des trajets fabriqués précédemment ou des méandres le long des trajets. Par conséquent, une intensité suffisante peut être fournie pour la fabrication additive 3D, même lors de l'utilisation de DEL en tant que sources de lumière.
Patent CA-3137887-A1 (CA)
Title: Inhibitor containing bicyclic derivative, preparation method therefor and use thereof
Inventor: SU YIDONG
IPC: C07D471/04
Filed: 2020-05-14
Abstract: Provided are an inhibitor containing a bicyclic derivative, a preparation method therefor and the use thereof. In particular, involved are a compound shown by general formula (I), a preparation method therefor, a pharmaceutical composition thereof, and the use thereof as an RET inhibitor in the treatment of cancers, inflammations, chronic liver diseases, diabetes, cardiovascular diseases, AIDS, and other related diseases, wherein each substituent in general formula (I) has the same definition as that given in the description.
Patent CA-3140102-A1 (CA)
Title: Compositions et methodes de traitement du cancer par immunotherapie anti-bcma
Inventor: SCHNEIDER DINA
IPC: C07K16/28
Filed: 2020-05-29
Abstract: L'invention concerne des récepteurs antigéniques chimériques contenant des domaines de liaison à l'antigène BCMA. L'invention concerne également des acides nucléiques, des vecteurs d'expression recombinants, des cellules hôtes, des fragments de liaison à l'antigène et des compositions pharmaceutiques, se rapportant aux récepteurs antigéniques chimériques. L'invention concerne en outre des procédés de traitement ou de prévention du cancer chez un sujet, et des procédés de production de lymphocytes T récepteurs d'antigènes chimériques.
Patent CA-3140460-A1 (CA)
Title: Cationic poloxamers and their use in transduction
Inventor: POULHES FLORENT
IPC: A61K48/00
Filed: 2020-07-10
Abstract: The invention relates to a method for the enhancement of the transduction of a target cells by a viral vector using a cationic block-copolymer introduced as an additive alone or formulated with nanoparticles. The method comprises a step of contacting a target cells with viruses and a cationic block co-polymer. The structure of this additive incorporates both hydrophilic and hydrophobic regions which represents different areas in the backbone of the polymer. This polymeric construction is ended by cationic chemical functions which contribute to further enhance the viral transduction. The invention also relates to new cationic poloxamers that can be used in the method of the invention. Furthermore, another embodiment of the present invention relates to the colloidal stabilization of iron-based nanoparticles using these polymers and their use in increasing transduction efficiency.
Patent CA-3141668-A1 (CA)
Title: Method and system for slag vitrification of toxic elements
Inventor: LALANCETTE JEAN-MARC
IPC: C03C1/02
Filed: 2020-07-21
Abstract: A method for slag vitrification of target elements, comprising forming target elements-containing pellets having a melting temperature lower than a melting temperature of a molten slag, mixing the target elements-containing pellets with the molten slag; and cooling. Vitrification of target elements using molten fayalite slag, comprising pelletizing the target elements with sodium oxide, mixing resulting pellets with the molten slag; and cooling is described.
Patent CA-3142278-A1 (CA)
Title: Aptamers against clostridium difficile
Inventor: SHANNON RONALD J
IPC: G01N33/573
Filed: 2020-06-05
Abstract: Compositions comprising aptamers capable of specifically binding to a surface protein of Clostridium difficile spore are provided. A method for detecting, enriching, separating, and/or isolating Clostridium difficile spores is provided.
Patent CA-3144306-A1 (CA)
Title: Device and method for producing liquid silicon
Inventor: SCHMID CHRISTIAN
IPC: C01B33/029
Filed: 2020-07-02
Abstract: An apparatus for forming liquid silicon comprises a device for bringing a gas into a high-temperature state in which it is at least partially present as plasma. The high temperature gas is conducted into a reaction space where it is contacted with a gaseous or particulate silicon-containing starting material. The silicon-containing starting material is introduced into the reaction space via a nozzle having a nozzle channel which opens directly into the reaction space. At the same time an inert gas is introduced into the reaction space in such a way that it protects the exit opening of the nozzle channel against thermal stress resulting from the high-temperature gas.
Patent CA-3145421-A1 (CA)
Title: Warp resistant panels
Inventor: GOSLING GEOFF W
IPC: E04B2/74
Filed: 2020-07-28
Abstract: A composite wood prefabricated wall panel configured for reduced moisture absorption includes a composite wood panel body, one or more connection components, and a priming layer. The composite wood panel body includes a front face, a rear face, and at least one edge. The one or more connection components are affixed to the rear face or the at least one edge, and the one or more connection components are configured to secure the composite wood prefabricated wall panel to one or more structural members of a prefabricated wall system. The priming layer is disposed over one or more surfaces of the composite wood panel body.
Patent CA-3148774-A1 (CA)
Inventor: TSE HENRY TAT KWONG
IPC: G01N15/14
Filed: 2020-07-30
Abstract: L'invention concerne un système et un procédé de détermination d'un paramètre de trajectoire de particules, comprenant la réception d'une pluralité de particules au niveau d'un canal microfluidique, l'application d'une force à chaque particule du canal microfluidique, l'acquisition d'un ensemble de données de chaque particule, la mesure d'une trajectoire de la particule, et la détermination d'un paramètre de trajectoire des particules.
Patent CA-3151661-A1 (CA)
Title: Microemulsion delivery systems for alcohol-soluble species including nonderivatized hormones
Inventor: SHADE CHRISTOPHER W
IPC: B82Y5/00
Filed: 2020-09-04
Abstract: Microemulsions are described where hydrophobic liquid droplets are distributed in a continuous hydrophilic liquid phase. The described microemulsions may be thought of as modified oil-in-water (MOIW) microemulsions, where both the "oil" and "water" phases of the microemulsion are modified. The oil phase droplets of the MOIW microemulsion are modified with alcohol and can solubilize alcohol-soluble species, including nonderivatized hormones. The polar continuous "water" phase of the MOIW microemulsion is modified with a sugar or sugar alcohol.
Patent CA-3154033-A1 (CA)
Title: Custom report builder
Inventor: SAIMANI JAYANTH
IPC: G06N5/00
Filed: 2022-03-29
Abstract: A method may include obtaining a knowledge graph including entities and relationships between pairs of entities, determining, for the knowledge graph, a first state including a first subset of the entities that are selectable by a user, receiving, from the user, a selection of an entity from the first subset, responsive to receiving the selection, determining, for the knowledge graph, a second state including a second subset of the entities that are selectable by the user, and generating a report using the knowledge graph and the second state.
Patent CA-3155131-A1 (CA)
Title: Lipid vesicle compositions with penetration enhancing agents
Inventor: FOLDVARI MARIANNA
IPC: A61Q19/00
Filed: 2020-09-23
Abstract: The present application is related to a pharmaceutical composition a biphasic lipid vesicle comprising a lipid bilayer comprising vesicle forming lipids; an oil-in-water emulsion stabilized by one or more surfactants; one or more compounds; and one or more penetration enhancing agents. The one or more penetration enhancing agents include one or more non-ionic surfactants having a hydrophilic-lipophilic balance (HLB) of about 10 or less, alone or combination with one or more penetration enhancing agents selected from one or more of terpenes, alkaloids, salicylate derivatives, and polycationic surfactants and combinations thereof. The present application is also related to a pharmaceutical composition comprising a biphasic lipid vesicle comprising a lipid bilayer comprising vesicle forming lipids; an oil-in-water emulsion stabilized by one or more polycationic surfactants; and one or more compounds.
Patent CA-3156025-A1 (CA)
Inventor: LEWIS NATHAN E
IPC: C12P21/02
Filed: 2020-11-19
Abstract: Les produits biopharmaceutiques glycosylés sont importants sur le marché pharmaceutique mondial. Malgré l'importance de leurs structures de glycane, les connaissances limitées de la machinerie de glycosylation empêchent encore la contrôlabilité de cet attribut de qualité critique. Pour faciliter la découverte de la spécificité de la glycosyltransférase et prédire des efforts de glyco-modification, l'invention concerne une approche permettant de modéliser la glycosylation de protéines thérapeutiques en tant que processus de Markov. Le modèle selon l'invention tire partie de la spécificité de la glycosyltransférase (GT) putative pour définir les voies de biosynthèse de tous les glycanes mesurés, et la modélisation de la chaîne de Markov sert à apprendre les activités des isoformes de la glycosyltransférase et à prédire la glycosylation qui suit une validation/invalidation de la glycosyltransférase. La méthodologie selon l'invention est appliquée à quatre agents thérapeutiques glyco-modifiés différents (c'est-à-dire le Rituximab, l'érythropoïétine, l'Enbrel et l'alpha-1 antitrypsine) produits dans des cellules de CHO, conjointement avec des profils d'o-glycosylation et de lipide. Les modèles selon l'invention prédisent avec précision la glyco-modification qui suit la glycosylation à liaison N et quantifient en outre l'impact de mutations de la glycosyltransférase sur des réactions catalysées par d'autres glycosyltransférases. En appliquant ces règles d'interaction GT-GT apprises identifiées à partir de mutants de glycosyltransférase unique, le modèle de l'invention prédit en outre le résultat de mutations de glycosyltransférase multigène sur les diverses biothérapies. L'invention concerne en outre l'étude de la O-glycosylation différentielle et des aspects lipidomiques. La présente approche de modélisation permet donc une glyco-modification rationnelle et l'élucidation de relations entre les glycosyltransférases et d'autres classes d'enzymes, ce qui facilite la recherche biopharmaceutique et favorise l'étude plus large de la glycosylation pour élucider la base génétique de changements complexes dans la glycosylation et le lipidome.
Patent CA-3158642-A1 (CA)
Title: Mixed fuel engine
Inventor: STAYKOV PETER
IPC: F02D41/30
Filed: 2020-10-28
Abstract: A system, method and circuit restricts the amount of a first fuel being provided to a duel-fuel engine, for example a diesel - natural gas engine; wherein a secondary circuit is provided, in parallel, to the circuit formed between the engine control unit, first fuel injector, and ground comprising a dummy load, and a normally closed switch inserted in the first fuel injection circuit; such that when the normally open switch is in a closed state the dummy load provides a resistance to the second sub-circuit, such that a total resistance in the second sub-circuit is equal to a total resistance in the first sub-circuit when the normally closed switch is in a closed state.
Patent CA-3159449-A1 (CA)
Inventor: QIAO JAMES
IPC: A47B5/00
Filed: 2022-05-19
Abstract: A scaffold having a structure assembly having a first vertical leg at a first corner of the assembly, a second vertical leg at a second corner of the assembly, a third vertical leg at a third comer of the assembly and a fourth vertical leg at a fourth corner of the assembly. The scaffold has a frame attached to the assembly. The frame having a deck upon which a user can stand that is disposed inside the rectangle. The deck has a plans table. The plans table has a closed position in which the plans table is flat and can support a weight of a user standing on the plans table, and has an open position in which the plans table is at an angle on which plans, drawings or documents can be placed on the plans table for viewing by a user standing on ground. A scaffold having connectors. A method of using a scaffold. A method for connecting a first scaffold to a second scaffold. A method for making a scaffold with connectors. A method for making a scaffold having a plans table.
Patent CA-3159889-A1 (CA)
Inventor: JEON JAEWON
IPC: C07K14/725
Filed: 2020-11-30
Abstract: The present invention relates to a chimeric antigen receptor specifically binding to a CD300c antigen or a receptor thereof, and immune cells expressing same, or the like. The chimeric antigen receptor specifically binding to a CD300c antigen or a receptor thereof according to the present invention specifically recognizes cancer cells expressing a CD300c antigen or CD300c receptor and directly effectively inhibits the growth of cancer, metastasis, or the like, and moreover, activates T cells and the like in the body through the inhibition of CD300c, and thereby can reduce side effects and also increase a cancer therapeutic effect, and thus is expected to be effectively used as an immunotherapeutic agent for various cancers.
Patent CA-3160532-A1 (CA)
Title: Method for detecting anomalies in ssl and/or tls communications, corresponding device, and computer program product
Inventor: UCCI DANIELE
IPC: H04L9/40
Filed: 2022-05-26
Abstract: Described herein is a method and network-security monitoring platform, also identified as Security Network Monitoring Platform (SNMP), for detecting anomalies in SSL and/or TLS communications set up in a communications network. The SNMP analyses (1004) data packets (DP) for detecting anomalous SSL and/or TLS handshake procedures in a monitoring interval, wherein each SSL and/or TLS handshake procedure comprises a first message sent by a respective client to a respective server for starting the respective SSL or TLS communication, and a corresponding second message sent by the respective server to the respective client. Next, the SNMP determines for each handshake procedure a first signature as a function of the data sent with the first message and a second signature as a function of the data of one or more certificates of the chain of certificates (CERT) sent with the second message. The SNMP then analyses the first and the second signatures to determine the respective popularity values. Moreover, the SNMP analyses each chain of certificates (CERT) to extract the information that indicates the fact that at least one of the certificates (CERT) of the chain is self-signed, and/or at least one of the certificates (CERT) has expired. During a training step, the SNMP trains a classifier (1008) using the popularity values and the information extracted from the certificates (CERT), so that the classifier (1042) supplies as output a value that indicates whether a given handshake procedure corresponds to a usual or to an anomalous handshake procedure. Consequently, during operation in steady-state conditions, the SNMP can use the classifier (1008) to supply, for each handshake procedure, a respective value that indicates whether the respective handshake procedure corresponds to a usual handshake procedure or to an anomalous handshake procedure and, in the case where (1010) at least one handshake procedure has been classified as anomalous, generate (1012) a notification that indicates the fact that the respective SSL or TLS communication presents an anomaly.
Patent CA-3163341-A1 (CA)
Inventor: CIRA PAUL
IPC: F24C15/16
Filed: 2022-06-15
Abstract: A grill basket including a basket portion having a bottom with sides extending upwardly and outwardly therefrom. A handle is removably engageable with one of a plurality of engagement assemblies that are provided on different sides of the basket portion. The handle is selectively engaged with different engagement assemblies in order to change the orientation in which the grill basket is able to be used. The grill basket further includes one or more removable dividers that are movable between a storage position and a use position.  In the storage position the one or more dividers are located proximate one or more sides of the basket portion and an interior compartment of the basket portion is substantially the same size as when the one or more dividers are completely removed from the basket portion. In the use position, the dividers are placed to divide the interior compartment into smaller compartments.
Patent CA-3164490-A1 (CA)
Title: Video coding in relation to subpictures
Inventor: SANCHEZ DE LA FUENTE YAGO
IPC: H04N19/70
Filed: 2020-12-18
Abstract: Concepts are described, including encoding, processing and decoding of a data stream having a video encoded thereinto, wherein the video comprises a plurality of pictures, wherein the data stream comprises a plurality of pictures in at least two layers, wherein the pictures of at least one layer are split into a predetermined layer-specific number of subpictures, one or more of the pictures or subpictures of one layer corresponds to one picture or subpictures in one or more other layer, and at least one of the subpictures comprises boundaries for boundary extension for motion compensation, and an indication that at least one of the boundaries of corresponding subpictures or corresponding pictures in different layers are aligned with each other.
Patent CA-3164875-A1 (CA)
Title: Waste transfer facility
Inventor: POLOWNIAK SHAWN
IPC: B09B5/00
Filed: 2022-06-22
Abstract: This disclosure relates to a waste transfer facility. The waste transfer facility includes a first level, the first level positioned at a first height, the first level including a first side, and a second side. The waste transfer facility also includes a second level, the second level positioned at a second height different than the first height, the second level including a plurality of waste receptacles, the plurality of waste receptacles including a first waste receptacle positioned adjacent to the first side to receive waste, a second waste receptacle positioned adjacent to the second side to receive waste, and a non-compliant waste receptacle to receive non-compliant waste, the non-compliant waste to be removed from the waste.
Patent CA-3166276-A1 (CA)
Title: Fluid pressure-activated valve assembly with flow restriction and systems and methods for in situ operations
Inventor: WERRIES MICHAEL
IPC: E21B43/26
Filed: 2021-10-13
Abstract: A well completion system for producing fluids from a wellbore provided in a subterranean reservoir is provided. The well completion system includes tubing segments connectable to one another along the wellbore. The tubing segments include injection segments provided along the wellbore in spaced-apart relation to each other, each injection segment has an injection valve toollessly operable between a closed configuration preventing fluid flow into the reservoir, and an open configuration allowing fluid flow into the reservoir. The tubing segments also include production segments provided along the wellbore in a staggered relation with respect to the injection segments and configured to allow fluids received from the reservoir to be produced from the reservoir. The tubing segments each are configured to include injection fluid passages and production fluid passages isolated from one another along the wellbore to enable synchronously injecting and producing fluids to and from the reservoir at respective fractured locations.
Patent CA-3170055-A1 (CA)
Inventor: XU QIAOBING
IPC: C07D241/04
Filed: 2021-03-02
Abstract: Disclosed are lipid compounds comprising imidazole heads and lipidoid nanoparticles (LNPs) comprising the lipidoid compounds disclosed herein for efficient nucleic acid delivery to T cells.
Patent CA-3170129-A1 (CA)
Title: Agents therapeutiques de melanome
Inventor: HANTASH BASIL M
IPC: A61P35/00
Filed: 2021-02-16
Abstract: La présente invention concerne deux agents thérapeutiques, oligopeptides P5 et P14, qui se sont avérés être sélectivement cytotoxiques vis-à-vis de multiples lignées cellulaires de mélanome in vitro. Ces oligopeptides offrent un traitement efficace pour tous les types de mélanocytes et d'étapes de mélanome pathogènes, et un traitement prophylactique efficace sur tous les individus présentant un risque élevé de développer un cancer de la peau. De plus, ces oligopeptides peuvent être formulés en un écran solaire pour servir d'agent prophylactique contre toute lésion précancéreuse ou nevi dysplasique qui pourraient se développer dans des groupes à risque élevé.
Patent CA-3170249-A1 (CA)
Inventor: MORGAN ANGELA
IPC: B65D25/20
Filed: 2021-04-01
Abstract: L'invention concerne un emballage conçu pour contenir un produit comprenant un élément actif et une étiquette. L'élément actif peut être placé sur une surface intérieure de l'emballage ou fixé à cette dernière, et l'étiquette peut être placée sur une surface extérieure de l'emballage ou fixée à cette dernière. L'étiquette peut être placée sur l'emballage pour recouvrir l'élément actif de telle sorte que l'élément actif ne puisse généralement pas être vu depuis l'environnement externe.
Patent CA-3171849-A1 (CA)
Inventor: TAKATANI Shinsuke
IPC: H01F1/147
Filed: 2021-06-17
Abstract: This electromagnetic steel sheet comprises a base material steel sheet of which one or both surfaces are at least partly coated with an insulating coating having an adhesive capacity, wherein the insulating coating has a logarithmic decrement of less than or equal to 0.3 in a temperature range of 25 to 100?.
Patent CA-3172435-A1 (CA)
Title: Dispositif d'epilation portable
Inventor: PAN YUPING
IPC: A61N5/06
Filed: 2020-03-24
Abstract: L'invention concerne un dispositif d'épilation portable (10), comprenant une partie tête (30), et un boîtier (20) relié à une extrémité de la partie tête (30). Un émetteur capable d'émettre de la lumière est disposé dans le boîtier (20), et la lumière émise par l'émetteur passe à travers la partie tête (30) et agit ensuite sur la peau pour éliminer les poils. La partie tête (30) est pourvue d'au moins une lampe de photothérapie (32), et la lumière émise par la lampe de photothérapie (32) agit sur la peau à travers la tête (30) et prend soin de la peau. Le dispositif d'épilation portable (10) a des fonctions riches et un bon effet de soin de la peau.
Patent CA-3173694-A1 (CA)
Title: Extrait de graines de moringa peregrina riche en 2,5-diformylfuran, son procede d'obtention et son utilisation dans des compositions cosmetiques
Inventor: DODINET ELIZABETH
IPC: A61P17/00
Filed: 2021-05-21
Abstract: L'invention concerne un extrait de graines de Moringa peregrina riche en composé  2,5-diformylfuran, plus spécifiquement un extrait du tourteau desdites graines et un procédé  d'extraction de l'extrait. Elle concerne également les compositions cosmétiques ou nutricosmétique comprenant ledit extrait et l'utilisation des dites compositions pour améliorer l'aspect de la peau, des muqueuses ou des phanères, pour relaxer, apaiser et déstresser la peau et prévenir et/ou à lutter contre les signes cutanés du vieillissement et/ou du photo-vieillissement et prévenir les tâches de vieillesse.
Patent CA-3174277-A1 (CA)
Title: Pongamia oil compositions, and methods for producing and using thereof
Inventor: DRAGULL KLAUS
IPC: A01N25/30
Filed: 2021-04-02
Abstract: Provided herein are pongamia oil compositions suitable for animal consumption, in particular human consumption, as well as methods of producing such compositions. The compositions are edible and non-bitter tasting, and have certain attributes that make such compositions suitable for use as and/or in various food and beverage products. Provided herein are also methods of analyzing pongamia oil.