baber/WOPTO huggingface dataset:
Patent AU-776785-B2 (AU)
Title: Compositions and methods for modulating serum cholesterol
Inventor: CHATTERJEE SUBROTO
IPC: A61K38/46
Filed: 2000-02-23
Granted: 2004-09-23
Abstract: Compositions and methods are provided for modulating serum cholesterol in a subject mammal. In one aspect, the invention features novel anti-lipemic drugs that include at least one identified effector of the Low Density Liproprotein (LDL) receptor and at least one identified serum cholesterol inhibitor. In a particular aspect, the drugs include one identified sphingolipid or protein modifying same linked to one identified serum cholesterol inhibitor. Additionally provided are methods for identifying anti-lipemic drugs capable of modulating the LDL receptor and specifically SREBP-1 maturation, including assays designed to identify pharmacoligical drugs capable of stabilizing or reducing serum cholesterol levels in a mammal and particularly a human patient.
Patent AU-615749-B2 (AU)
Title: Secure personnel monitoring system
Inventor: BOWER DAVID S
IPC: H04Q9/00
Filed: 1989-05-26
Granted: 1991-10-10
Abstract: A personnel monitoring system includes a tag (60) worn by each monitored person. The tag repeatedly emits digital radio signals, and a predetermined bit in the signal changes with time according to a predetermined pattern. Monitoring apparatus (12) detects the radio signals and sends an absence alarm signal if the signals cease. The monitoring apparatus detects spurious, forged signals which do not replicate the predetermined pattern of variation and provides a forgery alarm signal. The tag may be attached to the person by a strap bearing parallel electrical conductors. Attempts to remove the tag by severing the strap cause electrical contact between the conductors. Such contact triggers a detector, which in turn alters the radio signal.
Patent AU-653310-B2 (AU)
Title: Process for the production of polyethylene
Inventor: KAO SUN-CHUEH
IPC: C08F4/655
Filed: 1993-04-15
Granted: 1994-09-22
Abstract: A process for the polymerization of ethylene or a mixture comprising ethylene and one or more alpha-olefins and, optionally, a diene, comprising passing, under polymerization conditions, the aforementioned monomer(s) into contact with a catalyst system comprising:     (a) the reaction product of   (i) a titanium based catalyst precursor having the formula MgaTi(OR)bXc (ED)d wherein     ED is an electron donor R is an aliphatic or aromatic hydrocarbon radical having 1 to 14 carbon atoms or COR' wherein R' is an aliphatic or aromatic hydrocarbon radical having 1 to 14 carbon atoms;     each OR group is the same or different;     each X is independently chlorine, bromine, or iodine;     a is 0.5 to 56;     b is 0, 1, or 2;     c is 2 to 116; and     d is 2 to 85; and   (ii) at least one activator having the formula    Al(R')eX'fHg    wherein     X' is Cl or OR'' R' and R'' are the same or different and are saturated hydrocarbon radicals having 1 to 14 carbon atoms     f = 0 to 1.5     g = 0 or 1    e+f+g = 3; and     (iii) an alkyl, alkoxy, aryl, or aryloxy phosphine oxide, or mixtures thereof, in an amount sufficient to replace about 1 to about 80 mole percent of the electron donor in the precursor, and in a molar ratio of phosphine oxide to titanium of 0.1:1 to 8:1 wherein component (a) is impregnated into an inorganic support; and     (b) a hydrocarbyl aluminum cocatalyst. d
Patent AU-694569-B2 (AU)
Title: Process for preparing levobupivacaine and analogues thereof
Inventor: FRAMPTON GRAHAM ANTHONY CHARLE
IPC: C07D211/60
Filed: 1995-10-23
Granted: 1998-07-23
Abstract: PCT No. PCT/GB95/02514 Sec. 371 Date Apr. 25, 1997 Sec. 102(e) Date Apr. 25, 1997 PCT Filed Oct. 23, 1995 PCT Pub. No. WO96/12700 PCT Pub. Date May 2, 1996A process for preparing levobupivacaine, racemic bupivacaine or another N-alkyl analogue thereof, comprises chlorinating pipecolic acid hydrochloride, amidation of the resultant pipecolyl chloride hydrochloride in solvent, without isolation, with 2,6-dimethylaniline, and alkylation of the resultant pipecolic acid 2,6-xylidide. Alternatively, the alkylation may be followed by the amidation.
Patent AU-567266-B2 (AU)
Title: Hardening of phenolic resin
Inventor: COUSIN MICHEL
IPC: C08G14/06
Filed: 1984-12-28
Granted: 1987-11-12
Abstract: In a process for hardening phenol-formaldehyde resol resins, comprising conducting the hardening of the resins with an acidic solution of water and/or an organic solvent having dissolved therein an aromatic sulphonic acid and/or concentrated sulphuric acid, the improvement comprising the hardening in the presence of aniline added to the phenolic resin beforehand in a quantity of between about 0.5 and 2% relative to the weight of the phenolic resin whereby the pot life is extended and the cure time is satisfactory, the resultant products being especially useful as prepegs.
Patent AU-695196-B2 (AU)
Title: Nucleic acid transfer system
Inventor: WELS WINFRIED
IPC: C12N1/21
Filed: 1995-10-31
Granted: 1998-08-06
Abstract: The invention pertains to a nucleic acid transfer system including a translocation domain of toxins, especially of diphtheria toxin suitable for targeting a nucleic acid, e.g. a gene, to a specific cell, and obtaining expression of said nucleic acid. The nucleic acid transfer system of the invention comprises a multidomain protein component and a nucleic acid component. Furthermore, the present invention relates to the multidomain protein, a nucleic acid encoding said protein, suitable amplification and expression systems for said nucleic acid, and processes for the preparation and uses of the above subject matters.
Patent AU-749670-B2 (AU)
Title: Method and apparatus for operating a satellite positioning system receiver
Inventor: KRASNER NORMAN F
IPC: H04W64/00
Filed: 1999-04-13
Granted: 2002-07-04
Abstract: A method for operating a location apparatus (25-27) in a satellite positioning system (10) in a client/server architecture and a location apparatus (25-27) for use in the satellite positioning system. An example of the operations of the method and location apparatus include determining and storing one or more sets of pseudorange correction parameters, each having a corresponding correction parameter time stamp, receiving one or more transmissions from one or more mobile units (12), in which the transmissions include one or more sets of pseudoranges, each having a corresponding pseudorange time stamp, and selecting, based on the correction parameter time stamps and the pseudorange time stamps, at least one of the sets of correction parameters for correcting at least one of the sets of pseudoranges.
Patent AU-627517-B2 (AU)
Title: Detection of human papillomavirus dna and its expression in cervical smears
Inventor: CERUTTI PETER
IPC: C12Q1/686
Filed: 1989-11-10
Granted: 1992-08-27
Abstract: The invention relates to the direct detection of human papillomavirus DNA. The recently developed polymerase chain reaction has been modified in order to improve sensitivity and specificity. It is possible, by choosing suitable oligonucleotide primers (amplimers) and reaction temperatures, for individual HPV genes to be identified among the total cell 4 DNA and amplified to such an extent that non-isotopic detection is possible. In addition, the use of reverse transcription allows deliberate amplification of spliced mRNA and thus an indication of premalignant or malignant states or lesions.
Patent AU-594309-B2 (AU)
Title: Pharmaceutical composition for combination therapy of hormonedependent cancers
Inventor: LABRIE FERNAND
IPC: A61K31/445
Filed: 1985-08-02
Granted: 1990-03-08
Abstract: A method of treating sex steroid dependent cancers in a warm-blooded animal which comprises administering a pharmaceutically effective amount of an antiandrogen and/or an antiestrogen and/or at least one inhibitor of sex steroid biosynthesis to the animal whose hormone output of the testes or ovaries, respectively, is blocked, with the proviso that the method of treating prostate cancer comprises administering pharmaceutically effective amounts of an antiandrogen and at least one inhibitor of sex steroid biosynthesis and with the further proviso that, if antiestrogen is used in treating breast cancer it is used in association with an antiandrogen and/or at least one inhibitor of sex steroid biosynthesis. The invention further relates to kits containing pharmaceutical compositions containing the active ingredients to be used in the novel combination therapy.
Patent AU-624891-B2 (AU)
Title: Polyolefin composition
Inventor: SEINERA HENRI
IPC: C08K13/02
Filed: 1990-01-05
Granted: 1992-06-25
Abstract: Coherent thermoplastic aggregates with very high content of pulverulent mineral materials, said aggregates comprised of the said mineral materials, further of polyolefin polymers and/or copolymers, and possibly additionally of miscellaneous known additives; characterized in that, with the aim of achieving a density near to or at most equal to the theoretical density of the pulverulent mineral materials entering into their composition, while still having excellent compatibility with the polymers of redispersion, i.e., the polymers into which the subject aggregates are to be mixed, the interparticle voids between the grains of the mineral materials, which grains are basically in contact with each other, are at most filled-in the presence of a fluidifacient agent-by at least one polyolefin polymer and/or copolymer having a fusion temperature and/or softening temperature at least equal to 60 DEG  C., and having a fluidity index (ASTM 1238) of at least 50.
Patent AU-674349-B2 (AU)
Title: Compositions containing glyceride oil/liquid wax and structuring fat, and uses of such compositions
Inventor: PEDERSEN ARNE
IPC: A23P20/10
Filed: 1993-09-24
Granted: 1996-12-19
Abstract: PCT No. PCT/DK93/00308 Sec. 371 Date May 8, 1995 Sec. 102(e) Date May 8, 1995 PCT Filed Sep. 24, 1993 PCT Pub. No. WO94/07373 PCT Pub. Date Apr. 14, 1994A composition for use as a substitute for petrolatum and for surface treatment of confectionery, food products and surfaces which get in contact therewith as well as for external treatment of animals and plants comprises (a) oxidation resistant glyceride oil and/or liquid wax, (b) solid wax, which may be omitted if (a) comprises liquid wax, (c) structuring fat, and optionally (d) additions selected from crystallization inhibitors, hydrolysis inhibitors, food product ingredients, additives to food products, diet supplements, bioactive substances, cosmetic ingredients, pigments, and solvents. The combination of oxidation resistant glyceride oil, wax and structuring fat provides a composition with a semi-transparent, petrolatum-like structure having a high taste and smell stability, good gloss and anti-sticking effect, regulated adhesion and a very fine crystal structure. The composition is biocompatible by topical and oral administration and may advantageously be used instead of petrolatum and mineral oil based surface treatment compositions.
Patent AU-589938-B2 (AU)
Title: Tryptophan derivatives
Inventor: MAKOVEC FRANCESCO
IPC: A61K31/40
Filed: 1985-12-05
Granted: 1989-10-26
Abstract: N-acylated derivatives of L-tryptophan of general formula (I), <IMAGE> (I)  in which R is selected from the group consisting of: (a) a phenyl group, mono-substituted or di-substituted in the meta and para positions with halogens, linear or branched alkyl groups containing from 1 to 9 carbon atoms, the cyano group or the trifluoromethyl group, (b) a benzyloxy group, mono-substituted or di-substituted in the meta and para position with substituents selected from those indicated at (a), and (c) a benzydryloxy group. The derivatives are used in therapy, particularly for human pain relief, in the treatment of pathological conditions of the central nervous system and of pathological intestinal conditions.
Patent AU-730136-B2 (AU)
Title: Method for the manufacture of a laser-precut pack
Inventor: OLIVIERI ALAIN
IPC: B65D75/58
Filed: 1997-12-31
Granted: 2001-03-01
Abstract: The invention relates to a method for the manufacture of a pack, particularly intended for undergoing preservation treatment, from at least one film (10) comprising two plastic layers, an upper (11) and a lower (12), which form the outer and inner faces of said pack, and a light-metal central layer (13) sandwiched between said upper and lower layers. According to the invention, prior to the operations to make said pack, a laser beam is applied solely to the lower layer of said film, said lower layer forming the inner face of said pack, in order to produce, virtually in the entire thickness of said lower layer, at least one perforation (14) forming at least one precut line.
Patent AU-593538-B2 (AU)
Title: Vectors and method for expression of human protein c activity
Inventor: BANG NILS ULRICK
IPC: C12N15/00
Filed: 1986-02-06
Granted: 1990-02-15
Abstract: The present invention relates to DNA compounds which encode human protein C activity. A variety of eukaryotic and prokaryotic recombinant DNA expression vectors have been constructed that comprise the novel protein C activity-encoding DNA and drive expression of protein C activity when transformed into an appropriate host cell. The novel expression vectors can be used to produce protein C derivatives, such as non- carboxylated, non-glycosylatedd, or non-hydroxylated protein C, and to produce protein C precursors, such as nascent or zymogen protein C, and to produce subfragments of protein C, such as active or inactive light and heavy chain. The recombinant-produced protein C activity is useful in the treatment and prevention of a variety of vascular disorders.
Patent AU-699446-B2 (AU)
Title: Phenolic resin compositions with improved impact resistance
Inventor: KANE JOHN F
IPC: F16D13/62
Filed: 1996-04-19
Granted: 1998-12-03
Abstract: Phenolic siloxane compositions are prepared in a first embodiment by combining phenol with an aldehyde and an alkoxy or silanol-functional silicone intermediate; in a second embodiment by combining a phenolic novolac resin with a formaldehyde donor and an alkoxy or silanol-functional silicone intermediate; and in a third embodiment by combining a phenolic resole resin with an alkoxy or silanol-functional silicone intermediate. Optionally, a catalyst to facilitate formation of a phenolic resin from phenol and formaldehyde can be added, a catalyst to facilitate condensation of the phenolic resin can be added, and at least one catalyst to facilitate hydrolysis and/or condensation of the silicone intermediate can be added. The phenolic resin catalyst can include acids, bases, and formaldehyde donors. The silicone intermediate catalyst can include organometallic compounds, amine compounds, and mixtures thereof. The ingredients react to form a phenolic siloxane composition comprising an IPN of siloxane and phenolic polymers, and having siloxane groups in the phenolic polymer. The phenolic siloxane composition has flame, heat and chemical resistance equal to or exceeding conventional phenolic resins, and has improved properties of impact resistance, tensile strength, flexural modulus, and density when compared to conventional non-siloxane phenolic siloxane compositions.
Patent AU-582642-B2 (AU)
Title: Substituted N-``(4-piperidinyl)alkyl`` bicyclic condensed oxazol- and thiazolamines
Inventor: JANSSENS FRANS EDUARD
IPC: A61K31/495
Filed: 1986-04-15
Granted: 1989-04-06
Abstract: Novel substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines of formula <CHEM>  wherein L is a radical <CHEM> the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof, which compounds have anti-depressive, anti-Parkinson and enterokinetic activity; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
Patent AU-736768-B2 (AU)
Title: Apparatus for a heat treatment of a particular food product
Inventor: HANSEN EJNER BJORN
IPC: H05B3/00
Filed: 1998-02-17
Granted: 2001-08-02
Abstract: A chamber serving for a heat treatment of a particular food product, which for example can be pre-processed potato pieces which are to be prepared as French fried potatoes, and therefore have a content of evaporable substances, such as fat. In the chamber is a grid for, during operation, carrying the product, and one or more quartz lamps for generating heat for the process. The chamber is furthermore fitted with an exhaust channel which via a filter device connects the chamber to the open. Above the grid is placed a cabinet which is open at the bottom, for mounting the quartz lamps. The cabinet is via an inlet duct connected to the open. In the inlet duct is placed a ventilator for sending an air flow into the cabinet via the inlet duct. The air acts as a shield which keeps for example fat vapors at a distance so that they cannot come into contact with the quartz lamps and disintegrate in the high temperature of these. Thereby, it is prevented that unhealthy and malodorous substances are produced during the process. The air shield furthermore cools the quartz lamps, which thereby will attain a long life.
Patent AU-709896-B2 (AU)
Title: A method of making a laminated substrate
Inventor: SISBARRO FREDERICK P
IPC: B65H39/16
Filed: 1996-05-01
Granted: 1999-09-09
Abstract: The invention relates to a method of making a laminated substrate for use in an immunodiagnostic device and a machine or apparatus for marking the substrate with reagent. The method of forming the laminated substrate creates a rollable chromatographic medium. The chromatographic medium can be biphasic or multiphasic. The biphasic chromatographic medium comprises a capture medium precast onto a plastic backing and a release medium. The release and capture media are bonded to a liner material such as a plastic film. The multiphasic chromatographic medium comprises a capture medium precast onto a plastic backing, a release medium, and a sample absorbent medium. The capture medium, the release medium and the sample absorbent medium are disposed on a liner material such as a plastic film. The biphasic and multiphasic laminates are prepared for use as immunoassays by a specially adapted machine or apparatus. The machine includes a leader, an unwind system, a reagent dispensing system, a substrate reject marking system, a drying system, and a rewind system. In one exemplary embodiment, the machine applies four reagents to the substrate. The particular reagents used in the machine will vary depending upon the immunoassay to be performed.
Patent AU-762785-B2 (AU)
Title: Method of coating and method of bonding
Inventor: LEACH ROGER JOHN
IPC: C03C27/10
Filed: 1999-10-08
Granted: 2003-07-03
Abstract: Coating (1,2) on a glass substrate (3) are formed by laying down layers of different thermosetting materials one upon the other in powder form on surface (4). The powder of transparent coating 1) has a higher-cure rate than that of color coating (2) so that when heat is applied, coating (2) remains in the melt condition while the coating (1) hardens, to bond with and enable rolling out onto coating (1), as well as bonding with a backing (5). Materials of different cure-rates are also used for bonding substrates together by bringing the two materials together while one is partly-cured and the other in the melt condition.
Patent AU-698894-B2 (AU)
Title: Saw blade holder
Inventor: FAVRE ROGER
IPC: B23D51/02
Filed: 1996-08-26
Granted: 1998-11-12
Abstract: The saw has a U-shaped frame with an identical blade holder at each end. Each holder consists of a block (35) with a lengthwise passage of the same cross-sectional dimensions as the blade (5) to guide and centre the blade end inserted into it, and has a locking screw (37) situated perpendicular to the passage to fix the blade in place. In a variant of the design the block can incorporate a second locking screw, situated opposite the first one to hold the blade between the tips of the two screws. Each blade holder can be attached to the T-section end (41) of the saw frame by one of the locking screws. The saw frame can be made from tubing, and each blade holder block is of light alloy. The saw handle is of a plastic material, foam-covered to prevent slip.
Patent AU-625166-B2 (AU)
Title: Disinfectant concentrate
Inventor: DISCH KARLHEINZ
IPC: C11D3/386
Filed: 1990-10-26
Granted: 1992-07-02
Abstract: In the cleaning and disinfection of endoscopes, the endoscope surfaces to be cleaned are successively (a) brought into contact with a cleaning solution which is heated to 55 DEG  to 65 DEG  C., kept at that temperature for 1 to 15 minutes and then drained off and which contains a low-foam nonionic surfactant, a proteolytic enzyme, at least one complexing agent and, optionally, other standard detergent constituents, and has a pH value of from 6 to 8; (b) brought into contact with a disinfectant solution which is heated to 55 DEG  to 65 DEG  C., kept at that temperature for 1 to 15 minutes and then separated off and which contains an aldehyde selected from the group consisting of formaldehyde and aliphatic C2-C8 dialdehydes and at least one complexing agent, and has a pH value of from 6 to 8; (c) washed at least twice with water of which the pH value is adjusted to pH 6-8, the water being heated to 55 DEG  to 65 DEG  C. at least in the final wash cycle; and (d) dried with sterilized hot air at 55 DEG to 65 DEG  C., water having a hardness of from 3 DEG  to 8 DEG Gh being used in steps (a) to (c).
Patent AU-638386-B2 (AU)
Title: Arrangement for timing moving objects
IPC: G04F10/00
Filed: 1990-12-24
Granted: 1993-06-24
Abstract: The device permits identification and determination of the instant when a plurality of vehicles (4) pass a reference line (30). 
<??>It comprises a mobile station (1) installed on the vehicle and a fixed station (2) arranged at the edge of a race track (3). The fixed station (2) transmits a synchronisation signal at low frequency of period T, which is received by a mobile station (1) which in its turn transmits a series of signals of duration Tn situated at a predetermined rank with respect to the time, to, marking each period T start. Conjointly, the mobile station (1) allots, to each signal Tn an identification code which is unique to a defined mobile object. The signals received by the fixed station (2) are stored in a memory storing, for each signal, its absolute time, its assignment to a given vehicle (4) and its amplitude. 
<??>The device is used for motor vehicle races comprising a large number of contestants. 
<IMAGE>
Patent AU-640728-B2 (AU)
Title: Improved method for purification of recombinant copper/zinc (cu-zn) superoxide dismutase from bacteria or eucaryotic cells
IPC: C12N9/02
Filed: 1990-11-07
Granted: 1993-09-02
Abstract: Disclosed is a method of increasing the yield of recovered solutions having an increased concentration of b isoform of an enzymatically-active polypeptide analog of Cu-Zn superoxide dismutase from a composition which comprises cells containing a, b and c isoforms of the polypeptide analog comprising treating the composition to separate soluble proteins from whole cells, cellular debris and insoluble proteins to obtain a solution containing such soluble proteins, including the a, b and c isoforms; treating the resulting solution with soluble proteins to produce three separate solutions, each of which has an increased concentration of one of either of the a, b or c isoform; recovering the separate solution with an increased concentration of the b isoform; combining the separate solution with an increased concentration of the a isoform with the separate solution with an increased concentration of the c isoform; treating the resulting combined solution to produce a solution with an increased concentration of the b isoform and recovering the then-resulting solution with an increased concentration of the b isoform.