baber/WOPTO huggingface dataset:
Patent EP-4101377-A1 (EP)
Title: Method for determining cardiac or respiratory activity of a subject and associated system
Inventor: GIL PAUL
IPC: A61B5/113
Filed: 2021-06-09
Abstract: The invention relates to a method for determining cardiac or respiratory activity of a subject, comprising a step of measuring and recording, over at least one period of time, sample measurements relating at least to a kinematic characteristic or a position of an accessory (2) worn by the subject's head and a step of processing those sample measurements for determining said cardiac or respiratory activity.
Patent EP-4124708-A1 (EP)
Title: Electric strike with a monitoring system
Inventor: ANDREU PALLEROLA ROGER
IPC: E05B47/00
Filed: 2021-07-27
Abstract: The present invention relates to an electric strike with a monitoring system, comprising: a box (1), a swivelling latch (2), an internal locking and unlocking mechanism which can be actuated by the core (10) of a coil (8), a PCB circuit (13), two PCB connecting strips (11), a monitoring system for monitoring the state of the internal mechanism comprising an internal microswitch assembly (14) connected to a PCB circuit (13) of the strike and which can be actuated by the core (10) of the coil (8). The present invention further comprises a monitoring system for monitoring the state of a door, provided with a microswitch assembly (12) connected to the PCB circuit (13) of the strike and actuated by an actuation lever (3) located in the latch of the strike, when the door is in the closed position and the latch of the door actuates said actuation lever (3).
Patent EP-4104072-A1 (EP)
Inventor: BALASSANIAN EDWARD
IPC: G06F16/683
Filed: 2021-02-11
Abstract: Techniques are disclosed relating to automatically generating new music content based on image representations of audio files. Techniques are also disclosed relating to implement audio techniques for real-time audio generation. Additional techniques are disclosed relating to implementing user-created controls for modifying music content. Yet more techniques are disclosed relating to tracking contributions to composed music content.
Patent EP-4126735-A1 (EP)
Inventor: BÜTLER ERICH
IPC: B66B19/00
Filed: 2021-03-22
Abstract: Die vorliegende Erfindung bezieht sich auf eine Universalkonsole (102) für ein Schienensystem (100) einer Aufzuganlage, wobei die Universalkonsole (102) einen positionierbaren und ausrichtbaren Hauptträger (112) und zumindest einen Montagepunkt (116) für zumindest eine Schiene (106) des Schienensystems (100) aufweist, wobei der Hauptträger (112) zwei untrennbar mit dem Hauptträger (112) verbundene Führungen (120) zum Führen je einer Richtschnur (118) aufweist, wobei der Montagepunkt (116) und die Führungen (120) in festen Relativpositionen zueinander angeordnet sind.
Patent EP-4126835-A1 (EP)
Title: Inhibiteurs de présentation d'antigène par hla-dr
Inventor: BARBAY J KENT
IPC: A61P43/00
Filed: 2021-03-30
Abstract: L'invention concerne des composés de chromanone, des compositions pharmaceutiques les contenant, des procédés de fabrication de ceux-ci, et des procédés d'utilisation de ceux-ci, y compris des procédés de traitement d'états pathologiques, de troubles et d'états associés à l'inhibition de la présentation d'antigène par HLA-DR
Patent EP-4132966-A1 (EP)
Inventor: SILLIBOURNE JAMES
IPC: C12N15/10
Filed: 2021-04-07
Abstract: La présente invention concerne des procédés de criblage de bibliothèques de transgènes, lesquels procédés garantissent qu'un seul transgène est inséré dans le génome de chaque cellule pour éviter une identification par faux positifs ou faux négatifs de transgènes fonctionnels.
Patent EP-4153857-A1 (EP)
Inventor: GIESSAUF HELMUT
IPC: F02M57/00
Filed: 2021-04-28
Abstract: Kraftstoffinjektor zur Einspritzung von Kraftstoff unter hohem Druck in einen Brennraum einer Brennkraftmaschine, mit einem mehrteiligen Gehäuse (1), wobei die Gehäuseteile (2; 3; 4; 5) gegeneinander flüssigkeitsdicht verspannt sind. Im Gehäuse (1) ist ein mit Kraftstoff befüllbarer Druckraum (8) mit einer darin längsverschiebbaren Düsennadel (10) ausgebildet, die zum Öffnen und Schließen wenigstens einer Einspritzöffnung (12) mit einem Düsensitz (11) zusammenwirkt und die mit ihrem dem Düsensitz (11) abgewandten Ende einen Steuerraum (18) begrenzt, dessen Druck eine in Richtung des Düsensitzes (11) wirkende Schließkraft auf die Düsennadel (10) ausübt und der mit einer Druckkammer (32) im Gehäuse (1) hydraulisch verbunden ist. Im Gehäuse (1) ist weiterhin ein Drucksensor (36) angeordnet, der dazu ausgebildet ist, den Druck in der Druckkammer (32) zu messen. Zwischen der Druckkammer (32) und dem Drucksensor (36) ist eine Membran (30) angeordnet, die den Drucksensor (36) von der Druckkammer (32) flüssigkeitsdicht trennt, wobei die Membran (30) zwischen zwei Gehäuseteilen (3; 4) eingeklemmt ist.
Patent EP-4157067-A1 (EP)
Inventor: LYDEN COLIN G
IPC: G01R27/02
Filed: 2021-06-01
Abstract: A device having an impedance measurement circuit that allows for reduction of flicker noise can be implemented in a variety of applications. A carrier suppression technique can be implemented that substantially removes the carrier signal with removal of noise artifacts associated with the carrier signal from sidebands of the carrier signal. Carrier suppression in an AC impedance measurement circuit can be implemented by sensing a carrier signal of the measurement circuit at a transmit location of the measurement circuit and subtracting a weighted version of the carrier signal at a receive location of the measurement circuit. One or more compensation impedances can be used such that the sidebands of the carrier signal are received with the carrier signal suppressed with respect to the receive location.
Patent EP-4161951-A1 (EP)
Inventor: CHAPUIS NICOLAS
IPC: C12N5/0786
Filed: 2021-06-08
Abstract: The present invention provides novel, easy-to-monitor and sensitive parameters, biomarkers and methods for the prediction of SARS-CoV-2 patients outcome, allowing in particular an early identification of patients evolving towards severe COVID-19 forms. The examples presented in the application show that a calprotectin-driven emergency myelopoisis in patients undergoing a switch toward a severe form of COVID 19 generates an innate immune cell signature of severe COVID-19. More precisely, the present inventors have found that the amount of CD14low/CD16+ monocytes, of HLA-DR low  classical monocytes and of CD16 low  neutrophils can independently or concomitantly be used as biomarkers of the severity of betacoronavirus infection, before the switch to the severe form of the infection (and related painful symptoms) actually occurs. The methods of the invention comprise the quantification, in a biological sample from an infected subject, of the amount of these immune cells. In addition, the Inventors have observed a surprising burst of calprotectin levels in COVID-19 patients that are undergoing a switch toward a severe disease. They therefore propose to use calprotectin plasma level as a biomarker of COVID-19 switch to severe form, and also as a therapeutic target for alleviating the disease symptoms.
Patent EP-4146117-A1 (EP)
Inventor: TITUS NOEL
IPC: G06K19/07
Filed: 2021-05-06
Abstract: Provided is a medical device assembly for detection of medical device components and/or mating thereof. The medical device assembly may include a first medical device component having at least one first resonant structure, which may have a first resonant frequency spectrum. A second medical device component may have at least one second resonant structure, which may have a second resonant frequency spectrum different than the first resonant frequency spectrum. Upon mating of the first medical device component to the second medical device component, the first resonant structure(s) and the second resonant structure(s) may combine to have a third resonant frequency spectrum, which may be different than the first resonant frequency spectrum and the second resonant frequency spectrum. A system and method are also disclosed.
Patent EP-4143449-A1 (EP)
Title: Guide device and mechanical system comprising such a device
Inventor: PAVALLIER PIERRICK
IPC: G01M13/04
Filed: 2021-05-28
Abstract: The present invention relates to a guide device (10), comprising: a metal component (20) in the form of a ring with a friction surface (22) for receiving a counter piece (2) in sliding frictional contact with oscillation; a wear detection system (30) for detecting wear of the friction surface (22), comprising one or more sensors (32); a wireless communication system (40) connected to the detection system (30) and configured to transmit information related to the wear of the friction surface (22) to the outside of the guide device (10); the guide device (10) being characterised in that the sensor (32) or sensors are arranged exclusively on a longitudinal edge (29) or on two longitudinal edges (29) of the ring, each longitudinal edge (29) being defined over at most two fifths of the length of the annular ring.
Patent EP-4090372-A1 (EP)
Inventor: SCARISBRICK ISOBEL A
IPC: A61P35/00
Filed: 2021-01-13
Abstract: Materials and methods for regulating lipid abundance by modulating Protease Activated Receptor 1 (PAR1) and Protease Activated Receptor 2 (PAR2) levels are provided herein. In a first aspect, this document features a method that includes (a) identifying a mammal as having a condition characterized at least by impaired lipid production, impaired cholesterol production, or both impaired lipid production and impaired cholesterol production; and (b) administering to the mammal an inhibitor of PAR1 and/or PAR2 in an amount effective to increase lipid production and/or cholesterol production in the mammal.
Patent EP-4111412-A1 (EP)
Title: Image intensity correction in magnetic resonance imaging
Inventor: PEETERS JOHANNES MARTINUS
IPC: G06T5/00
Filed: 2021-07-07
Abstract: Disclosed herein is a medical system (100, 300) comprising a memory (110) storing machine executable instructions (120) and an image segmentation algorithm (122). The image segmentation algorithm is configured for outputting one or more predetermined anatomical regions within initial magnetic resonance imaging data (124) descriptive of a predetermined field of view (109) of a subject (318). The medical system further comprises a computational system (104), wherein execution of the machine executable instructions causes the computational system to: receive (200) the initial magnetic resonance imaging data (124); receive (202) the image segmentation comprising the one or more anatomical regions within the magnetic resonance imaging data in response to inputting the initial magnetic resonance imaging data into the image segmentation algorithm; select (204) at least one of the one or more anatomical regions as a selected image portion (128) using a predetermined criterion; and reduce (206) image intensity within the selected image portion to provide intensity corrected magnetic resonance imaging data.
Patent EP-4181851-A1 (EP)
Inventor: REYMOND MARC
IPC: A61G13/10
Filed: 2021-07-15
Abstract: Die vorliegende Erfindung betrifft ein System zum Schutz von medizinischem Personal und/oder eines Patienten vor luftgetragenen Krankheitserregern in einem Operationsumfeld und ein Verfahren zum Schutz von medizinischem Personal und/oder eines Patienten vor luftgetragenen Krankheitserregern in einem Operationsumfeld.
Patent EP-4188402-A1 (EP)
Inventor: MALANCHIN ROSELLA
IPC: A61P17/10
Filed: 2021-07-29
Abstract: La présente invention concerne des compositions probiotiques contenant Lactobacillus plantarum, Lactocillus rhamnosus et Lactobacillus reuteri utiles dans la prévention et/ou le traitement de maladies et/ou de troubles cutanés.
Patent EP-4188689-A1 (EP)
Inventor: GOUGH PETER
IPC: B31B50/62
Filed: 2021-07-27
Abstract: This invention relates to an apparatus for manufacturing a container, the container being made of paperboard and being formed from at least two elements adhered together. An apparatus for use in manufacturing a container comprises a first inlet connected to a supply of dry steam; a second inlet connected to a supply of hot air; a mixing chamber, the first inlet and the second inlet being fluidly connected to the mixing chamber such that a flow of dry steam from the first inlet mixes with a flow of hot air from the second inlet; and a delivery nozzle fluidly connected to the mixing chamber and configured to direct said mixed flow of hot air and dry steam to a part of at least one of said elements.
Patent EP-4196424-A1 (EP)
Inventor: GABRIËL JAN
IPC: B66C23/92
Filed: 2021-08-05
Abstract: Described is a lifting device with a force-absorbing base to which a boom with hoisting cable for lifting a load in substantially vertical direction is tiltably connected. The lifting device is provided with an auxiliary device for counteracting tipover of the boom in the case of sudden loss of load. The auxiliary device is connected to the base of the lifting device, provides a contact surface which is in permanent contact with a contact surface of the boom or comes into contact therewith in the case of tipover, and further comprises a drive and control system which is configured to stop the boom movement when a predetermined force between the contact surfaces is exceeded as a result of the boom tipping over. The described auxiliary device can take an autonomous form and can be arranged on a lifting device.
Patent EP-4110378-A1 (EP)
Title: Mitigation of statistical bias in genetic sampling
Inventor: ALBACKER LEE ALAN
IPC: G01N33/50
Filed: 2021-02-26
Abstract: Provided herein are methods, systems, and storage media that may find use, e.g., in sequencing (e.g., via NGS) polymorphic alleles, such as detecting loss-of-heterozygosity (LOH) of a human leukocyte antigen (HLA) gene or another polymorphic human gene. In some embodiments, the methods and systems comprise obtaining observed allele frequencies and observed binding propensities for the alleles to one or more bait molecule(s), then applying an optimization model to determine adjusted allele frequencies that take into account these binding propensities, thereby adjusting for and/or minimizing any potential bias rooted in differential allele: bait binding propensities with regard to determination of allele frequency.
Patent EP-4214253-A1 (EP)
Title: Copolymère acrylique absorbant les uv pour la réalisation de lentilles intraoculaires souples
Inventor: TERRISSE JEAN
IPC: C08F220/30
Filed: 2021-09-10
Abstract: Le matériau selon l'invention est un copolymère acrylique absorbant les rayonnements ultra-violets, destiné à la réalisation de lentilles intraoculaires souples. Il est obtenu à partir d'un mélange de monomères comprenant au moins un monomère acrylique ou méthacrylique et un monomère absorbeur de rayonnements ultra-violets de formule ( I), R étant un groupement méthyle ou éthyle, et R 1  étant l'hydrogène ou le groupement de formule (II).
Patent EP-4125947-A1 (EP)
Title: Novel anucleated cells for the treatment of diseases
Inventor: HETT SUNITA R
IPC: C12M1/26
Filed: 2021-03-26
Abstract: The present disclosure takes advantage of non-naturally existing, novel, anucleated platelets or platelet-like cells or platelet variants (collectively referred to as PECs) or derivatives thereof (i.e., genetically engineered), which share at least one common receptor, ligand or an antigen with endogenous cells that are targets for autoantibodies and effectuate their clearance. The present disclosure also takes advantage of viral adhesion or entry receptors or genetically engineered PECs or derivatives thereof, which are engineered to express viral adhesion or entry receptors, that specifically binds to viral proteins on viruses or viral particles and effectuate their clearance.
Patent EP-4126016-A1 (EP)
Inventor: TURTLE CAMERON J
IPC: A61K39/00
Filed: 2021-03-31
Abstract: Combination therapies that include (i) an immune cell that expresses a chimeric antigen receptor (CAR) or similar molecule and (ii) a compound that preserves or potentiates the  in vivo  actions of tumor necrosis factor alpha (TNFα) against cancer cells are described. The combination therapies result in the killing of antigen-negative cells in the vicinity of immunotherapy targeted-antigen-positive cells reducing the survivability of escape variants and providing other benefits.
Patent EP-4226441-A1 (EP)
Inventor: RINGEL ANTON
IPC: H01M8/0202
Filed: 2021-09-23
Abstract: L'invention concerne une plaque séparatrice, en particulier une plaque monopolaire (1) ou une plaque bipolaire (2), pour un empilement de piles à combustible (10). La plaque séparatrice comprend une région de connexion latérale (3) ayant un élément de connexion (4) qui est de forme conique, au moins en sections, pour former un cône d'insertion (5) pour un contact de fiche (6) d'un dispositif de surveillance de tension de cellule. L'invention concerne également un empilement de piles à combustible (10) ayant au moins une plaque séparatrice selon l'invention, ainsi qu'un procédé de production d'une plaque séparatrice.
Patent EP-4133188-A1 (EP)
Inventor: GOLDSTEIN EDWARD
IPC: F16B37/14
Filed: 2021-04-06
Abstract: Connection mechanisms utilizing nut restrainers and methods of use are presented, particularly as they apply to high-strength bolted connections for steel structures. Nut restrainers may include a base plate and a cap that accepts insertion of a nut, and may include deformable or removable protrusions that allow the nut and/or a cap to move laterally to accept a bolt that is inserted non-concentrically with the nut. A method of positioning a nut restrainer concentric with a bolt hole accurate to within the radial tolerance of the bolt hole is further disclosed.
Patent EP-4130943-A1 (EP)
Inventor: WU DONGPING
IPC: G06F3/0346
Filed: 2021-04-21
Abstract: Embodiments of this application relate to the field of electronic technologies, and provide a touch operation method and a device, so that in a scenario in which an electronic device is held with one hand, response processing can be performed for a touch operation on a side edge of the electronic device, and a finger of a user does not need to reach a control in a middle region of a screen to perform an operation. Therefore, an operation amplitude of the finger can be shortened, a one-hand operation of the user can be facilitated, and user experience can be improved. A specific solution is as follows: The touch operation method is applied to an electronic device having a curved screen, where the curved screen includes a side edge of the electronic device. After detecting that the side edge is touched, the electronic device determines a target region, where the target region is a contact region of a user on the side edge in a holding mode. The electronic device prompts a location of the target region. After detecting a touch operation performed by the user on the target region, the electronic device performs a corresponding response operation for the touch operation. Embodiments of this application are applied to the touch operation.
Patent EP-4123687-A1 (EP)
Inventor: KOUDA Ryousuke
IPC: H01L21/60
Filed: 2021-01-19
Abstract: A semiconductor device includes a mounting substrate having a first surface, a semiconductor chip mounted on the first surface and having a second surface facing a side opposite to the first surface, and a wire extending from a first joint point on the first surface toward a second joint point on the second surface and electrically connecting the mounting substrate and the semiconductor chip to each other by connecting the first joint point and the second joint point to each other. The wire includes a first part, a first bent portion, a second part, a second bent portion, and a third part arranged in order from the first joint point toward the second joint point. The first part is positioned on the first surface side with respect to the second surface when viewed in a first direction along the first surface and the second surface. The first bent portion is positioned on the first surface side with respect to the second surface and is bent such that the second part is guided to the second surface side when viewed in the first direction. The second part extends over the second surface on a side opposite to the first surface when viewed in the first direction.
Patent EP-4247525-A1 (EP)
Inventor: CHEN XUEFANG
IPC: B01D63/10
Filed: 2021-11-02
Abstract: Disclosed is a membrane filter unit (1) comprising: (a) a filter case (2) for housing a membrane (3); (b) an inner tube (4) housing a wastewater chamber (4A) and a hollow core tube (7), a middle tube (5) housing a pure water chamber (5A) and an outer tube (6) housing a feed water chamber (6A), wherein the inner tube (4), the middle tube (5) and the outer tube (6) are coaxially arranged and formed inside the filter case (2) between the inner wall of the filter case (2) and other components positioned within the filter case and inner tube (4) is formed by at least a part of the central hollow tube and at least a part of the hollow core tube (7) sealingly fitted with each other; (c) the hollow core tube (7) having a top opening (7A) at a top end (7TE) and a bottom opening (7B) at a bottom end (7BE), and having a water collecting channel (8) on its outer wall and positioned coaxially inside the case (2), wherein the top opening (7A) is adapted to open into the wastewater chamber (4A); and (d) a membrane (3) having an inner peripheral surface (3A), a top outer peripheral surface (3B), a bottom outer peripheral surface (3C) and a side outer peripheral surface (3D); and arranged around the core tube (7) such that the inner peripheral surface (3A) of the membrane is spirally wound around the core tube (7) and the side outer peripheral surface (3D) is capable of permeation of raw water through its surface; wherein the membrane has a bottom cover (9) and a top cover (10), the top cover (10) sealingly engaged with the top outer peripheral surface (3B) of the membrane (3) and comprising a through central hole (10A) adapted for and sealingly fitted to the core tube (7) to facilitate passage of waste water through the core tube (7) into the waste water chamber (4A); and the bottom cover (9) engages with the bottom outer peripheral surface (3C) of the membrane (3) having a bottom cover central hole (9A) spanning beyond the bottom opening (7B) of the core tube (7) to allow passage of water from the outer tube (6) through the membrane (3) and the bottom cover central hole (9A) of the core tube (7) and wherein the bottom cover (9) of the membrane (3) is capped by a bottom cap (9B) which sealingly engages with the bottom cover (9) and the top cap (2T) of the filter case (2) comprises an inner wall and an outer wall and wherein from the inner wall of the top cap (2T) two hollow concentric tubes descend downwardly, a central hollow tube (4C) and a peripheral hollow tube (4P) each having respective inner walls and outer walls.
Patent EP-4229454-A1 (EP)
Inventor: MCNEIL JANEE ASHLEY
IPC: G02B5/18
Filed: 2021-10-14
Abstract: A grating coupler may be fabricated by exposing a photopolymer layer to grating forming light for forming periodic refractive index variations in the photopolymer layer. The photopolymer layer may be exposed to apodization light for reducing an amplitude of the periodic refractive index variations in a spatially-selective manner. The apodization may also be achieved or facilitated by subjecting outer surface(s) of the photopolymer layer to a chemically reactive agent that causes the refractive index contrast to be reduced near the surface(s) of application. The apodized refractive index profile of the gratings facilitates the reduction of optical crosstalk between different gratings of the grating coupler.