baber/WOPTO huggingface dataset:
Patent AT-E459724-T1 (AT)
Inventor: MICHNICK STEPHEN W
IPC: C12N15/09
Filed: 2000-06-26
Granted: 2010-03-15
Abstract: The present invention describes a rapid and efficient <i>in vivo</i> library-<i>versus</i>-library screening strategy for identifying optimally interacting pairs of heterodimerizing polypeptides. It allows for the screening of a protein library against a second protein library, rather than against a single bait protein, and thus has numerous applications in the study of protein-protein interactions. Additionally, it allows for the application of different selection stringencies. Two leucine zipper libraries, semi-randomized at the positions adjacent to the hydrophobic core, were genetically fused to either one of two designed fragments of the enzyme murine dihydrofolate reductase (mDHFR), and cotransformed into <i>E. coli.</i> Interaction between the library polypeptides was required for reconstitution of the enzymatic activity of mDHFR, allowing bacterial growth. Analysis of the resulting colonies revealed important biases in the zipper sequences relative to the original libraries, which are consistent with selection for stable, heterodimerizing pairs. Using more weakly associating mDHFR fragments, we increased the stringency of selection. We enriched the best performing leucine zipper pairs by multiple passaging of the pooled, selected colonies in liquid culture, as the best pairs allowed for better bacterial propagation. This competitive growth allowed small differences among the pairs to be amplified, and different sequence positions were enriched at different rates. We applied these selection processes to a library-<i>versus</i>-library sample of 2.0 x 10<6> combinations, and selected a novel leucine zipper pair which may be appropriate for use in further <i>in vivo</i> heterodimerization strategies.
Patent AT-E233890-T1 (AT)
Inventor: KERN HEINZ
IPC: C06B45/12
Filed: 2000-07-12
Granted: 2003-03-15
Abstract: A pyrotechnical primer for igniting propellant powder for sleeveless ammunition comprises an igniting element ( 4 ) and a coil ( 1 ). The energy required for triggering is transmitted in an electromagnetic manner (inductively). The inductive primer is cost-effective, entirely combustible, easy to produce and is not provided with residues that damage the functioning of the weapons. The primer has a base construction such that the primer can be used in all conventional weapons calibres. To this end, the ignition element ( 4 ) and the coil ( 1 ) are located on a mutual, flat, combustible consumable or support material ( 5 ).
Patent AT-E263482-T1 (AT)
Inventor: SJOELUND MARTIN
IPC: A01K1/00
Filed: 2000-08-02
Granted: 2004-04-15
Abstract: A gate for use in cattle handling systems, where animals pass between different areas separated by fences and passage from one area to another takes place through the gate. The gate is spring biased to occupy a closed position, in which it is lockable by at least one catch member being releasable in response to the approach of an animal identified as allowable for passage. The catch member is arranged to provide free passage at all times through the gate in one opening direction and to be actuatable for releasing the gate for opening in the opposite opening direction.
Patent AT-E324943-T1 (AT)
Inventor: ZHANG XUMU
IPC: C07B53/00
Filed: 2000-09-19
Granted: 2006-06-15
Abstract: Chiral ligands and transition metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The chiral ligands include chiral C1-C6 TunaPhos ligands. The ruthenium TunaPhos complex reduces ketones to the corresponding alcohols with 95-99.6% enantioselectivity. The transition metal complexes of the chiral ligands are useful in asymmetric reactions such as asymmetric hydrogenation, hydride transfer, hydrosilylation, hydroboration, hydrovinylation, hydroformylation, hydrocarboxylation, isomerization, allylic alkylation, cyclopropanation, Diels-Alder reaction, Heck reaction, isomerization, Aldol reaction, Michael addition and epoxidation reactions.
Patent AT-E277961-T1 (AT)
Inventor: KITAJIMA TAKASHI
IPC: C08G59/50
Filed: 2000-10-18
Granted: 2004-10-15
Abstract: A curing agent for epoxy resins, the curing agent containing as an active ingredient a compound represented by the formula (1) or a salt thereof and an amine compound or a salt thereof, the curing agent being characterized in that at least one of the compound represented by the formula (1) and the amine compound is a salt of thiocyanic acid; and an epoxy resin composition having the curing agent incorporated therein: NH2N(R<1>) (R<2>) wherein R<1> and R<2> are the same or different and each represents alkyl having 1 to 8 carbon atoms, aryl, a nitrogen-containing heterocyclic group or when taken together, represents alkylene having 2 to 11 carbon atoms or a group represented by -R<3>-R<4>-R<5>-wherein R<3> and R<5> are the same or different and each represents alkylene having 1 to 8 carbon atoms, and R<4> is an oxygen atom, a sulfur atom or a group =NR<6> or =NNH2, wherein R<6> is a hydrogen atom or alkyl having 1 to 8 carbon atoms.
Patent AT-E422550-T1 (AT)
Inventor: SMALLRIDGE ANDREW
IPC: C12P7/26
Filed: 2000-12-13
Granted: 2009-02-15
Abstract: The invention provides a method of synthesis of a substituted or unsubstituted carbinol compound, comprising the steps of subjecting the corresponding substituted or unsubstituted aromatic aldehyde to acyloin condensation mediated by yeast in the presence of either (a) a supereritical fluid or (b) a liquefied gas, and recovering the carbinol compound. Preferably the yeast is Saccharomyces cerevisiae. In a particularly preferred embodiment the aromatic aldehyde is benzaldehyde and the carbinol is phenylacetylcarbinol, according to the reaction (I): in which the benzaldehyde, the pyruvic acid, or both may optionally be substituted.
Patent AT-E353106-T1 (AT)
Inventor: WILSEY CHRISTOPHER D
IPC: G01N33/483
Filed: 2000-12-14
Granted: 2007-02-15
Abstract: A reagent and method for determining the levels of 3-hydroxybutyric acid in a sample are provided. The reagent comprises a ferricyanide salt, a catalytic amount of a first enzyme operative to catalyze the oxidation of 3-hydroxybutyric acid in the sample, a cofactor corresponding to said first enzyme, and a catalytic amount of a second enzyme operative to catalyze the oxidization of the cofactor and the reduction of the ferricyanide. The reagent is incorporated into a test strip that generates an electrical output signal indicative of the level of 3-hydroxybutyric acid when the reagent is contacted with a sample.
Patent AT-E426759-T1 (AT)
Inventor: GODEL MARTIN
IPC: F16H25/18
Filed: 2001-01-11
Granted: 2009-04-15
Abstract: The device has at least one drive unit with two separate acting bodies (4a, 5a, 4b; 5b) with facing acting surfaces (16a,17a;16b,17b) diverging in a drive direction (18a,18b), a lifting unit (23a,23b) between them in contact with the acting surfaces of both bodies and a drive arrangement (15) for causing the bodies to approach and a resulting displacement of the lifting unit along the acting surfaces to produce a drive movement that can be used.
Patent AT-E370451-T1 (AT)
Inventor: KUSTERER STEFAN
IPC: G06F15/00
Filed: 2001-03-20
Granted: 2007-09-15
Abstract: The present invention discloses a method, computer program product and system for adjusting roles in a computer system (100) that launch application services (301-307) by a first user who is assigned to at least one role. A first role (110) calls a second role (150) by reference (111). Both roles comprise representations of applications services (101, 102, 103) and (104, 105). When representations in the second role are modified, for example, application services are added (106, 107), a delta list (112) for the first reference is automatically created to conditionally prevent the first role (110) from referencing to at least some of the modified representations of the second role (150). This is achieved by using a rule database (118) containing rules about application services that are mutually exclusive and checking for conflicts between the representations of the first role and modified, second role. A second user, e.g. a system administrator, can accept or reject automatically created delta entries (114) in the delta list (112). <IMAGE>
Patent AT-E249468-T1 (AT)
Inventor: MOSZNER NORBERT
IPC: A61K6/083
Filed: 2001-04-11
Granted: 2003-09-15
Abstract: Novel acrylic phosphonic acid compounds are claimed Acrylic phosphonic acid compounds (I) of formula (1) are claimed. Independent claims are included for: (i) a dental material containing the acrylic phosphonic acid (I) and (ii) polymers and copolymers prepared by (co)polymerization of the acrylic phosphonic acid (I). R<1> = 1-10C alkylene or 6-14 C alkylene; R<2> = H, 1-10C alkyl or 6-10C aryl; Y = oxygen, sulfur, 1-8C alkylene or is missing; n = 1-5; X = CN when 1 is 1 and Z is missing; X = CONR<3> with R<3> equal to H, 1-10C alkyl or 6-10C aryl whereby when n is 1, Z is H or 1-10C alkyl or phenyl and when n=2-5, Z is an aliphatic, aromatic or araliphatic 1-14C hydrocarbon whereby Z and R<3> may form part of an overall ring
Patent AT-E276134-T1 (AT)
Inventor: TRANI GIORGIO
IPC: B31B37/00
Filed: 2001-06-06
Granted: 2004-10-15
Abstract: A method for producing containers from a film of heat-sealable flexible material, comprising unwinding a portion of film (11) stored in roll form (10). The film (11) is made of a heat-sealable single- or multilayer flexible material. The flaps (14,15) of the unwound portion are folded until they are side by side or overlapped along a narrow band (16). The resulting new lateral edges are folded further so as to form longitudinal accordion-like portions and the bottom (19) is then formed with a transverse heat-sealed portion (18) which is produced simultaneously with a median cut of the heat-sealed portion (18), separating two pairs of adjacent containers (23a,23b). The heat-sealed bottom is inserted into the container by an extent which is equal to the half width of the lateral accordion-like portion and a longitudinal heat-sealed portion (17) is then produced in the region where the flaps (14,15) lie side by side and/or overlap, blocking the bottom and the accordion-like portion, simultaneously with a complete or partial cutting of the longitudinal heat-sealed portion (17). <IMAGE>
Patent AT-E321616-T1 (AT)
Inventor: RUPOLI SIMONE
IPC: B21D11/12
Filed: 2001-10-12
Granted: 2006-04-15
Abstract: A method applied to ordinary stirrup bending machines in which there is a tray (10) with an openable bottom (11) for forming bars and shaped parts of considerable length. The method includes opening of the openable bottom (11) of the tray (10), during the advancement of the sections (2), so as to allow the passage of bent portions (2a) of the sections (2) whose length (h') exceeds the height (H) of the guiding tray (10). <IMAGE>
Patent AT-E411687-T1 (AT)
Inventor: WRENCH EDWIN H
IPC: H04L9/08
Filed: 2001-12-08
Granted: 2008-10-15
Abstract: A system for facilitating secure network communications includes a security computer system and corresponding software. The security system is utilized in conjunction with a voice browser residing on a server system. A user accesses the network by placing a call to the voice browser system. The voice browser includes a software module that creates a secure connection to the security system. The user provides an identification to the voice browser system that is transferred to and verified by the security system. Once the identification is verified, the user is prompted by the voice browser system to speak a phrase for voice verification. The verification speech signals are transferred from the voice browser system to the security system to verify those speech signals against speech signals of a particular authorized user associated with the identification and stored in a database. When the user is verified, the security system retrieves a user private key and certificate from the database. In response to the user subsequently accessing a web site residing on a secure server, the secure server and voice browser system initiate a secure key exchange. During the key exchange, data packets containing security information are transferred from the voice browser system to the security system for processing, while security information from the security system is transferred to the secure server via the voice browser system. The resulting session key is securely transferred to the voice browser system to facilitate secure communications between the voice browser system and secure server. <IMAGE>
Patent AT-E484829-T1 (AT)
Inventor: HANEGRAAF ANDRE ADRIANUS HENRICUS
IPC: G11B33/04
Filed: 2001-06-27
Granted: 2010-10-15
Abstract: The present invention relates to a container for a data carrier, in particular a compact disc, consisting of at least one first flexible plastic film, an intermediate flexible plastic film, and a second flexible plastic film, which films each have an upper edge, a lower edge and a first and a second side edge, and which are interconnected via said lower edges and said first and said second side edges, using an adhesive agent, so as to form a unitary flexible container. The present invention furthermore relates to a storage system for data carrier containers. <IMAGE>
Patent AT-E374443-T1 (AT)
Inventor: DU HUNG
IPC: H02K3/44
Filed: 2001-11-30
Granted: 2007-10-15
Abstract: An electric motor having an armature which includes a coating of thermally conductive plastic applied in a conventional injection molding process. The armature also includes a fan which is integrally formed from the thermally conductive plastic applied to the armature. This completely eliminates the need to apply one or more coatings of a trickle resin to the armature. It also eliminates the need to separately form and secure a fan by a suitable adhesive to the armature, which together significantly simplifies the manufacturing and cost of the armature. The plastic coating also better fills the spaces between the magnet wires, thus promoting even more efficient cooling and better holding of the magnet wires stationary relative to one another. The thermally conductive plastic coating may be mixed with other suitable materials to provide a density approximately equal to the magnet wires. This eliminates the need to balance the armature after the injection molding step.
Patent AT-E393856-T1 (AT)
Inventor: GRAFF PIERRE
IPC: B31F1/07
Filed: 2001-12-12
Granted: 2008-05-15
Abstract: The multilayer absorbent paper sheet, comprising two layers (12, 14) of cellulose wadding, each with a weight of 15 - 35 g/sq m, has the first layer embossed with a first set of motifs in selected zones (16), made from embossed protuberances (18) projecting towards the second layer (14) and forming open cells in the sheet's outer surface. <??>At least some of the protuberances (18) have their tips (19) attached to the inner surface of the second layer. The first layer of the paper has a second set of motifs made from a series of smaller embossed protuberances (38) of smaller dimensions than the first and having a higher density. The second set of protuberances are set in recesses (36) so that their tips (39) are in contact with the second layer and some are attached to it.
Patent AT-E331150-T1 (AT)
Inventor: BONDIOLI EDI
IPC: F16D3/38
Filed: 2001-01-05
Granted: 2006-07-15
Abstract: From a chamber (18), which can be supplied by a pressure greasing unit (16), there extend several branched channels (20; 22) which reach the points where the lubricant is to be supplied; a passage with a very small cross section (30, 32) is created between said chamber (18) and each branched channel (20, 22) so that a high pressure is reached inside said chamber (18) and - with injection through the grease nipple (16) - a metered supply of lubricant through each of said passages is thus obtained.
Patent AT-E361086-T1 (AT)
Inventor: VILLA CLAUDIO
IPC: A61K36/00
Filed: 2001-01-25
Granted: 2007-05-15
Abstract: A preparation, in particular for pharmaceutical use, includes rutin and/or a water-soluble derivative thereof and an extract of Lespedeza Capitata obtained with the use of an aqueous-alcohol solvent. The extract of Lespedeza Capitata preferably contains at least 1% of total flavonoids and at least 0.05% of Lespecapitoside.
Patent AT-E358489-T1 (AT)
Inventor: LATHE RICHARD FRANK
IPC: A61K31/5685
Filed: 2001-02-15
Granted: 2007-04-15
Abstract: A method is provided for treating a patient in need of therapy for acute neuronal degeneration due to metabolic compromise of central or peripheral nervous system cells comprising administering to that patient a therapeutically effective amount of a 7alpha-hydroxy substituted steroid selected from 7alpha-hydroxy-derivatives of estradiols, dehydroepiandrosterones and pregnenolones, and metabolic precursors thereof. Use of such compounds for manufacture of medicaments and neuroprotective compositions are also provided.
Patent AT-E353335-T1 (AT)
Inventor: SOLOMON BEKA
IPC: C07K16/18
Filed: 2001-03-09
Granted: 2007-02-15
Abstract: More than 90% of mutations found in the p53 protein produce a conformational change in p53 which results in the exposure of an epitope, which is otherwise hidden in the hydrophobic core of the molecule. A single chain antibody (scFv) which specifically recognizes this common mutant epitope in mutant p53 but not in wild type p53 is disclosed. Also described are a DNA molecule encoding the scFv, pharmaceutical compositions comprising the antibody and methods of treatment using the pharmaceutical compositions.
Patent AT-E471533-T1 (AT)
Inventor: HEIDARI BABAK
IPC: G03F7/26
Filed: 2001-04-10
Granted: 2010-07-15
Abstract: Method in connection with the production of a template, preferably for nanoimprint lithography, which template comprises a flat plate ( 1 ) of a first material and a three-dimensional structure (6, 8) of a second material, arranged on the plate, said second material introductory being applied on said plate, in the method, to form the structure. The second material is thereafter fixed to the plate the second material is thereafter fixed to the plate of the first material, by heat treatment (Q) at at least 100° C., for the production of the template. A template is produced by use of the method.
Patent AT-E460475-T1 (AT)
Inventor: HORWITZ DAVID
IPC: A61K35/12
Filed: 2001-04-11
Granted: 2010-03-15
Abstract: The invention relates to compositions and methods useful for preventing graft rejection in a recipient following organ transplantation.
Patent AT-E373296-T1 (AT)
Inventor: LAFFARGUE FRANCK
IPC: G02F1/133
Filed: 2001-04-10
Granted: 2007-09-15
Abstract: Method of calculating new luminance value data based on original luminance value data to be displayed on a matrix display device, where luminance value data are coded in sub-fields, and double-line addressing for the least significant sub-fields is used for reducing the addressing time. A reduction of the difference between the new data and the original data is obtained by computing a new common value for the least significant sub-fields of a set of neighboring or adjacent lines, and new values for the most significant sub-fields of each line of said set of adjacent lines. The method comprises embodiments which are applicable to both binary and non-binary sub-fields.
Patent AT-E367301-T1 (AT)
Inventor: KALLIO MIKKO
IPC: B60R19/52
Filed: 2001-06-06
Granted: 2007-08-15
Abstract: Connection for a grill panel (10) of a motor vehicle, incorporating a pair of mountings for the grill panel. To provide a safe and dimensionally stable connection for the grill panel, it is proposed, inter alia, that each mounting be associated with a hinge (20; 30) for a side door of the vehicle.
Patent AT-E376205-T1 (AT)
Inventor: FRISTEDT TOMMY
IPC: A47C7/74
Filed: 2001-07-02
Granted: 2007-11-15
Abstract: Methods and apparatus for controlling the temperature of a seat such as a vehicle seat are disclosed. The apparatus includes an electrical heater disposed in the seat, a cooling unit such as a cooling element and a fan, a detector for detecting the temperature associated with the electrical heater, and a controller for controlling the electrical heater and the cooler based upon the detected temperature and upon the humidity algorithm comprising a predetermined set of calculations of the humidity of air at different temperatures.
Patent AT-E333988-T1 (AT)
Inventor: BUSCH DETLEF
IPC: B32B27/32
Filed: 2001-05-09
Granted: 2006-08-15
Abstract: The invention relates to the use of a polyolefinic film, with at least one layer, which is made from polyolefinic polymers, whereby said polyolefinic film comprises a bonding layer as outer layer. Said bonding layer contains at least 50 wt. % based on the weight of the layer of a maleic anhydride modified polyolefin. The film is used for printing, metallising or coating.
Patent AT-E366189-T1 (AT)
Inventor: HOTTEBART FRANCOIS
IPC: B60C17/00
Filed: 2001-07-20
Granted: 2007-07-15
Abstract: The invention concerns a method for assessing the range of a motor vehicle run-flat system comprising at least for each wheel a tire casing, a deflation alarm and means supporting the running tread of the tire casing when the casing is deflated, which method, from the instant the deflation alarm has detected a predetermined deflating threshold, includes the steps of: periodically measuring the distance covered and a parameter C(t) characteristic of the running conditions; determining on the basis of C(t) and the measured distance over Deltat a quantity characteristic of potential elementary damage of the system during the elapsed time Deltat; calculating an estimate of the global damage by combining the calculated elementary damage levels since the start of flat running; and transmitting to the vehicle driver a quantity related to that estimate of the flat running system global damage.
Patent AT-E317249-T1 (AT)
Inventor: GILLIGAN SEAN
IPC: A61L31/00
Filed: 2001-12-10
Granted: 2006-02-15
Abstract: An intraluminal prosthesis composed of a self-expandable stent and a biodegradable constraining element being capable of biodegrading in vivo over a predetermined period of time to permit radial expansion of the stent. The constraining elements are applied to the stent to produce a compressed configuration. Dissolution of the constraining elements in vivo allows for expansion of the stent to an expanded configuration.
Patent AT-E311148-T1 (AT)
Inventor: NEISZ JOHANN J
IPC: A61B17/00
Filed: 2001-12-28
Granted: 2005-12-15
Abstract: Surgical instruments, implantable articles and surgical procedures disclosed for treating medical disorders, particularly incontinence. Improved surgical sling procedures are disclosed. Novel surgical instruments and kits for use in sling procedures are also disclosed. The present invention affords options for surgeons with concomitant advantages to the patient and the healthcare provider.
Patent AT-E474572-T1 (AT)
Inventor: SHAPIRA NATHAN
IPC: A61K31/00
Filed: 2001-11-30
Granted: 2010-08-15
Abstract: The subject invention provides methods of promoting wound healing comprising the administration of a therapeutically effective amount of a composition comprising topiramate. Compositions may administered to a wound site via a salve, ointment, or as a component of a bandage or bioadhesive applied to the site of injury.