Patent SG-11201907375V-A (SG)
Title: Plant extracts enriched with ipolamiide derivatives as immunosuppressants for treating immunological disorders
Inventor: GUIMARÃES CRISTIANO RUCH WERNECK
IPC: A61K31/352
Filed: 2018-02-19
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 23 August 2018 (23.08.2018) WIP0 I PCT omit VIII °nolo VIII VIII IIII iflo (10) International Publication Number WO 2018/148816 A2 (51) International Patent Classification: CO7D 311/94 (2006.01) (21) International Application Number: PCT/BR2018/050037 (22) International Filing Date: 19 February 2018 (19.02.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: BR1020170033180 17 February 2017 (17.02.2017) BR (71) Applicant: ACHE LABORATORIOS FARMACEUTI- COS S.A. [BR/BR]; Rod. Presidente Dutra, s/n° - Km 222, Porto da Igreja, 07034-904 Guarulhos, SP (BR). (72) Inventors: GUIMARAES, Cristiano Ruch Werneck; Alameda dos Anapurus, 883, Apto 131 B, Moema, 04087-002 Sao Paulo, SP (BR). VITOR, Carlos Eduar- do; Rua Joao Ant6nio de Oliveira, 544, Apto 103 Turim, Mooca, 03111-010 Sao Paulo, SP (BR). PESSA, Lisandra Ravanelli; Travessa Vila Real, 8, Vila Mariana, 04118-095 Sao Paulo, SP (BR). REIS, Romulo Dragani; Praca Marisa Marques, 44, Apto 95, Vila Rosana, 07072-080 Guarulhos, SP (BR). MASCARELLO, Alessandra; Rua Santa Izabel, 451, 07023-022 Guarulhos, SP (BR). GAMA, Fernando Henrique De Souza; Rua da Penha, 55, 07197-130 Guarul- hos, SP (BR). (74) Agent: DANIEL ADVOGADOS; Av. Republica do Chile, 230, 3° andar, Centro, 20031-170 Rio De Janeiro, RJ (BR). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: without international search report and to be republished upon receipt of that report (Rule 48.2(g)) in black and white; the international application as filed contained color or greyscale and is available for download from PATENTSCOPE (54) Title: COMPOUNDS, PROCESS OF PRODUCTION OF COMPOUNDS, ENRICHED EXTRACT, ENRICHED EXTRACT ACTIVE FRACTIONS, ENRICHED EXTRACT PROCESS OF PRODUCTION, METHOD FOR SELECTING VEGETAL BIO- MASS FOR ENRICHED EXTRACT PRODUCTION, COMPOSITION AND USE FOR TREATMENT OF IMMUNOLOGICAL DISORDERS Figure 3 1-1 © (57) : The invention describes novel and inventive isolated compounds and the process of producing compounds and extracts with i mmunosuppressive activity, from plants of the genus Stachytarpheta. In this way, the present application also describes novel and V inventive compositions and its use for the treatment of immunological disorders. The present invention is in the fields of pharmacy, 13 medicine and chemistry.