baber/WOPTO huggingface dataset:
Patent JP-2002503945-A (JP)
Title: 新規治療用結合分子複合体
IPC: A61K47/48
Filed: 1996-04-18
Abstract: (57)【要約】
接続成分により互いに結合した２以上の異なるエフェクター分子を有する、選択された標的に結合する構造体を製造する。エフェクター分子の少なくとも１つ（例、抗体）は標的に結合し、残りのエフェクター分子の少なくとも１つ（例、酵素）は治療用である。接続成分は、リポソーム、タンパク質、デンドリマー型ポリマーまたは相補的核酸鎖であり得る。接続成分は、結合分子が標的に結合すると同時に、治療分子が標的と物理的に相互作用するのを可能にするのに十分な長さおよび／または柔軟性を有していてもよい。該構造体は、疾患の治療、イムノアッセイおよびセンサーに使用することができる。細胞のin vivo遺伝子操作の場合、組換え用配列および結合部位を有するポリヌクレオチド、該結合部位に結合したＤＮＡ結合性タンパク質および該ポリヌクレオチドに結合したモータータンパク質を含有する複数の遺伝子操作複合体をリポソーム接続成分に充填する。プロホスホリパーゼがリポソーム表面上に位置していてもよく、それが活性化されて該リポソームを開裂し、該複合体を遊離させる。
Patent JP-2000506759-A (JP)
IPC: D06F71/02
Filed: 1997-03-17
Abstract: An ironing press including a working board (1) supported on a lower base (2) to which a rear arm (4) supporting a heated plate (3) is pivotably connected about a relative pivot shaft (6). The pivot shaft (6) is located behind and below the working board (1). Resilient return means and pressing means are housed under the working board (1) and apply respective relative torques to the heated plate (3) to move it into the open position or the working position by exerting axial thrust on a connecting arm (8) of which the front end (10) is slidable back and forth on the lower base (2) of the working board, while its back end (11) is pivotable about a transverse intermediate shaft (9) on the rear arm (4) of the heated plate (3). A large space is thus provided for housing the resilient return means and the pressing means, which may optionally be mechanised and automated.
Patent JP-H11504482-A (JP)
Title: 映像信号復号化システム用後処理方法及びその装置
IPC: H04N7/30
Filed: 1996-04-25
Abstract: (57)【要約】
映像信号復号化システムにおいて使用され、前記システムの画質を向上させることのできる後処理フィルタリング装置であって、現フレームの復号化映像データを格納するメモリ手段と；対象画素データを格納するバッファと；対象画素データをフィルタリングしてフィルタリングされた対象画素データを生成する手段と；対象画素データと所定の閾値とを加算して上位値を生成する手段と；フィルタリングされた対象画素データと上位値とを比較して第１選択信号を発生する第１比較手段と；第１選択信号に応じて、バッファに格納された対象画素データまたはフィルタリングされた対象画素データを選択する第１選択手段と；対象画素データから所定の閾値を減算して下位値を生成する手段と；第１選択手段で選択されたフィルタリングされた対象画素データまたは対象画素データのいずれかと下位値とを比較して第２選択信号を発生する第２比較手段と；第２選択信号に応じて、第１選択手段で選択されたフィルタリングされた対象画素データまたは対象画素データのいずれか、または対象画素データを選択して、フィルタリング結果を出力する第２選択手段と；フィルタリング結果を用いて、メモリ手段に格納された対象画素データを更新する手段とを含む後処理フィルタリング装置。
Patent JP-2002514915-A (JP)
Title: トランスジェニック植物についての選択方法
IPC: C12N15/31
Filed: 1998-02-05
Abstract: (57)【要約】
細胞の集団から、１つ以上の選択可能な遺伝的に形質転換された細胞を選択するための選択方法が記載される。この方法において、細胞の集団は、選択可能な遺伝的に形質転換された細胞および潜在的な非形質転換細胞を含む。選択可能な遺伝的に形質転換された細胞のそれぞれは、第１の発現可能なヌクレオチド配列、および必要に応じて、第２の発現可能なヌクレオチド配列を含む。この方法において、培地中に低濃度で存在する場合、成分またはその代謝誘導体は、選択可能な遺伝的に形質転換された細胞および非形質転換細胞の両方についての栄養分である。この方法において、培地中に高濃度で存在する場合、成分またはその代謝誘導体は、非形質転換細胞に対して毒性である。第１のヌクレオチド配列は、成分またはその代謝誘導体を、培地中に高濃度で存在する場合、選択可能な遺伝的に形質転換された細胞についての栄養分に転換し得る遺伝子産物をコードする。この方法は、細胞の集団を培地に導入する工程を包含し、ここで培地は、必要に応じて、高濃度の成分またはその代謝誘導体を含む。この方法において、成分またはその代謝誘導体は、選択可能な遺伝的に形質転換された細胞についての炭水化物および窒素の両方の供給源である。あるいはこの方法において、成分の一部が代謝基質として作用し、誘導体化された基質に代謝的に転換される場合、この誘導体化された基質は、遺伝子産物に対してアロステリック効果を提供し得る。
Patent JP-2000508261-A (JP)
IPC: C08J7/043
Filed: 1997-04-08
Abstract: PCT No. PCT/DK97/00149 Sec. 371 Date Oct. 8, 1998 Sec. 102(e) Date Oct. 8, 1998 PCT Filed Apr. 8, 1997 PCT Pub. No. WO97/38853 PCT Pub. Date Oct. 23, 1997A multilayered packaging material, in particular for flexible packagings, comprising when seen from the outer face to the inner face an outer, substantially transparent film (1) having a reverse print (2) on its inwardly facing surface; an intermediate layer (3, 4) connected to the printed surface of the outer film (1) and applied in fluid form to the inner, printed surface of the outer film (1); a metallization layer (5) connected to the inner face of the gas barrier layer (3) and an inner sealing medium layer (7), preferably in form of a polyolefine.
Patent JP-2000510342-A (JP)
Title: アポミクト種子の作成
IPC: A01H5/00
Filed: 1997-05-13
Abstract: (57)【要約】
本発明は、とりわけ（ｉ）細胞内もしくはその膜において存在することが当該細胞を胚形成性にするタンパク質をコードする核酸配列を植物材料に形質転換すること、（ii）形質転換した材料を植物またはその心皮を含む部分に再生すること、ならびに(iii)胚嚢付近における配列の発現のステップを含むアポミクト種子を作成する方法を提供する。そのタンパク質は、好ましくは、リガンド結合ドメインが欠損もしくは機能的に不活性となるように修飾されたロイシンリピートリッチレセプターキナーゼであり得る。
Patent JP-2000509953-A (JP)
Title: 上りチャンネルのフィルタ
IPC: H04H60/96
Filed: 1998-03-10
Abstract: (57)【要約】
下りチャンネルと上りチャンネルを有する多チャンネル通信システムにおいて、上りチャンネルの損失を制御するフィルタ（１０）。このフィルタは、下りチャンネルのフィルタ回路網（３６）と上りチャンネルのフィルタ回路網（３８）から成っている。下りチャンネルのフィルタ回路網は、下りチャンネルの信号を通すものであって、上りチャンネルのフィルタ回路網（３８）に接続された少なくとも１つの共振回路構成要素（例えば、コンデンサ）を含む。上りチャンネルのフィルタ回路網（３８）は、上りチャンネルの信号を通すものであって、少なくとも１つの共振回路（例えば、対地直列ＬＣトラップ）を含む。複合共振回路は、少なくとも一部、上りチャンネルのフィルタ回路網（３８）の共振回路構成要素と、下りチャンネルのフィルタ回路網（３６）の共振回路構成要素によって形成される（例えば、複合型の対地直列ＬＣトラップ）。さらに、上りチャンネルのフィルタ回路網（３８）は、上りチャンネルの周波数帯域の信号を減衰させるように設計された減衰回路網（４０）も含む。
Patent JP-2002503409-A (JP)
Title: 電話ネットワークを通じた無接続時間データ・メッセージ通信
IPC: H04M1/00
Filed: 1998-04-14
Abstract: (57)【要約】
電話ネットワーク（１４）を介して呼出し側（２０）と受信者（２２）との間で通信する方法で、以下のステップを含む。呼出し側は、呼出し側の電話回線から受信者の電話回線（２４）に呼を出し、受信者は呼（２６）を受信するが応答せず、通信コード（２８）からメッセージを判別する。その結果、コードが呼出し側と受信者との間で送信される。
Patent JP-2001523255-A (JP)
Title: 抗血栓剤
IPC: A61K31/4025
Filed: 1998-04-30
Abstract: (57)【要約】
本出願は、本明細書中に定義した式（Ｉ）の新規化合物(またはそれらの医薬的に許容され得る塩)、それらの製造のための方法および中間体、式（Ｉ）の新規化合物を含んでなる医薬品製剤、並びにトロンビン阻害剤としての式（Ｉ）の化合物の使用に関する。
Patent JP-2001525670-A (JP)
Title: 有機化合物の選択的酸化方法
IPC: C12P13/00
Filed: 1998-05-12
Abstract: (57)【要約】
オキシダーゼを使用して、Ｈ 2 Ｏ 2 を発生させることにより酸素化された有機化合物を製造する方法が開示されている。発生するＨ 2 Ｏ 2 は、金属含有触媒の存在下で被酸化性有機基質を酸化するのに使用される。酸素の存在下で水素または電子供与体と反応して、Ｈ 2 Ｏ 2 を生成することができるオキシダーゼ酵素と組み合わせた、酸化ケイ素及びAg、CO、Ce、Mn、Fe、Cu、Cr、Ti、V、Mo及びWの酸化物の不溶性キャリアーの酵素系も開示されている。
Patent JP-2002505830-A (JP)
Title: 周波数ホッピングシーケンスに従って無線信号を交換する無線通信システム、基地局、および移動ユーザ端末
IPC: H04B1/713
Filed: 1999-04-16
Abstract: (57)【要約】
少なくとも１つの基地局および移動加入者端末を含み、様々なタイムスロットおよび周波数スロットで無線信号を送受信する無線通信システムは知られている。無線信号は、所定の周波数ホッピングシーケンスに従って、ユーザチャネルおよびシグナリングチャネル上で伝送される。本発明によれば、基地局および加入者端末は、タイムスロットパターンの最初の部分では周波数ホッピングの連続を生成せずに固定周波数（ｆ０）を提供し、タイムスロットパターンの少なくとも１つの別の部分では反復方式（ＬＧＮＲ）を使用して疑似ランダム周波数ホッピングシーケンス（ＴＨＳ）を生成する周波数スロットの変化を制御する制御手段（ＣＴＲ）を有する。基地局は、疑似ランダム周波数ホッピングシーケンス（ＴＨＳ）を計算するために、加入者端末に入力値（ＣＷ）を送信する。加入者端末を登録するための制御手段は、この疑似ランダム周波数ホッピングシーケンスに従って周波数変化を制御する。これは、登録信号を伝送するために、計算した周波数ホッピングシーケンス、すなわち入力値に基づいて発生させた、完全に記憶する必要はない周波数ホッピングシーケンスが既に使用されていることを意味する。
Patent MD-20010277-A (MD)
Title: Hot-water boiler
Inventor: SOCOLOV VALERII
IPC: F24H1/00
Filed: 2001-08-29
Abstract: The invention relates to the thermodynamics and may be used in the capacity of thermogenerator in the water heating systems in private life and in industry.The boiler contains a body, provided with an offtake, a combustion chamber, provided with a burner, water inlet and outlet pipes, horizontal convective surfaces, forming a gas line in the form of labyrinth, along the gas line there are placed pipe heat exchangers coupled with the water jacket, ducts for outlet from the boiler space of the combustion products.The result consists in the intensification of the temperature transmission process by increasing the time of contact of the combustion products with the heat exchanger.
Patent MD-20040081-A (MD)
Title: Process and reactor for nonthermal decomposition and pasteurization of organic materials by electroporation
Inventor: SCHULTHEISS CHRISTOPH
IPC: A23L13/70
Filed: 2002-08-21
Abstract: According to the invention, into the chamber of the reactor, which is a component part of the installation for obtaining of food products or of components thereof, the biological products in the harvested form, whole or chopped up, are subjected to the action of pulsating electric fields. As a result of action of said electric fields, in the cell membranes are formed pores, which irreversibly open, thus making more accessible the content of the cells. That is attained by means of some groups of electrodes under high voltage, which are placed in the zone of one longitudinal wall of the reactor, along the axes intersecting the material subjected to processing, and of the earthed electrodes, placed in the opposite longitudinal zone. Each group of electrodes is connected to an accumulator of electric power, for example, to a Marx generator, for switching with the view of rapid changing, the electric fields of different directions between the loaded and earthed electrodes. Claims: 9Fig.: 5
Patent MX-149614-A (MX)
Inventor: WILKINSON RICHARD L
IPC: G11B7/258
Filed: 1980-06-11
Abstract: A video disc (11) is made by using the heat of a modulated focussed laser beam (13) as in prior proposals, but in order to get a more accurate record track, the medium on which the video disc record is made includes nitro-cellulose, or some other explosive material which is heated to its autoignition point when the heat in the focussed laser beam is above the critical level at which a pit is to be formed in the surface of the record.
Patent NZ-202457-A (NZ)
Title: 3-(1-substituted-4-piperidyl)-1,2-benzisoxazole derivatives and pharmaceutical compositions
Inventor: STRUPCZEWSKI J T
IPC: A61P25/20
Filed: 1982-11-10
Abstract: Novel 3-(1-substituted-4-piperidyl)-1,2-benzisoxazoles, processes for the preparation thereof, and methods of treating psychoses employing compounds and compositions thereof are disclosed.
Patent NZ-218522-A (NZ)
Title: Exchanging hardness cations and removing nitrate ions from liquids by ion exchange
Inventor: PRUNAC ALAIN DENIS LOUIS
IPC: B01J47/04
Filed: 1986-12-05
Abstract: A process is disclosed for exchanging hardness ions and selectively removing nitrate ions from a liquid, e.g. water, comprising passing the liquid through a cation/anion exchange resin mixture, whereby (i) hardness ions are exchanged, (ii) cations and nitrate ions, present in the liquid before its passage through the resin mixture, are each independently removed or reduced to a desired level, and (iii) the anion exchange resin is loaded with nitrate ions to at least 80% of its nitrate removal capacity, and wherein the resin mixture is at least initially regenerated with chloride salt. If the process is used to soften and selectively remove nitrate ions from water, the disadvantageous precipitation of calcium carbonate and/or calcium sulfate during subsequent regeneration of the resin mixture can be avoided. The invention also discloses a resin mixture suitable for use in the process.
Patent NZ-218924-A (NZ)
Title: 4,5,6-substituted-2-pyrimidinamines and pharmaceutical uses
Inventor: TORLEY LAWRENCE WAYNE
IPC: A61P29/00
Filed: 1987-01-13
Abstract: This disclosure describes novel 4,5,6-substituted-N-(substituted-phenyl)-2-pyrimidinamines having anti-asthmatic activity.
Patent NZ-223290-A (NZ)
Title: Injectable aqueous solutions of non-steroidal anti-inflammatories containing mixed micelles of cholanic acid salts and lipids
Inventor: FERRO ALBERTO
IPC: A61K9/10
Filed: 1988-01-26
Abstract: Aqueous mixed micelle solutions comprising cholanic acid salts and lipids used for the solubilization of non-steroidal anti-inflammatories and for the preparation of locally tolerable pharmaceutical administration forms for such medicaments, are described.
Patent NZ-225053-A (NZ)
Title: Use of doxazosin in pharmaceutical compositions for suppressing fibrosis and lipid deposition
Inventor: SWINDELL ARCHIE CALHOUN
IPC: A61K31/505
Filed: 1988-06-16
Abstract: This invention relates to the use of doxazosin or a pharmaceutically acceptable acid addition salt thereof as an agent for retarding the development of atherosclerosis in a mammal, especially for reducing atherosclerotic plaque involvement and for retarding and reducing both the fibrosis and lipid deposition of developing atherosclerotic plaques associated with atherosclerosis.
Patent NZ-230424-A (NZ)
Title: Liposomal composition comprising an externally disposed antigen
Inventor: POPESCU MIRCEA C
IPC: A61K9/00
Filed: 1989-08-24
Abstract: Disclosed is a vaccine against an infective agent, the vaccine comprising a liposome having an exterior and an interior and having externally disposed affinity associated antigen material of at least one, preferably nonpartitioning, antigen representative of said infective agent. Also disclosed is a method of preparation and use of this vaccine.
Patent NZ-236200-A (NZ)
Title: 3-oxime-indol-2-one derivatives and pharmaceutical compositions
Inventor: WATJEN FRANK
IPC: A61P25/18
Filed: 1990-11-23
Abstract: A method of treatment with compounds having the formula <CHEM>  wherein R<1> is hydrogen, C1-6-alkyl which may be branched, C3-7-cycloalkyl, benzyl, phenyl which may be substituted, acyl, hydroxy, C1-6-alkoxy, CH2CO2R' wherein R' is hydrogen or C1-6-alkyl which may be branched, CH2CN, CH2CONR<IV>R<V> wherein R<IV> and R<V> independently are hydrogen or C1-6-alkyl, or CH2C(=NOH)NH2; R<2> is hydrogen, benzyl, C1-6-alkyl which may be branched, or C3-7-cycloalkyl; R<4>, R<5>, R<6>, R<7> independently are hydrogen, C1-6-alkyl which may be branched, phenyl, halogen, C1-6-alkoxy, NO2, CN, SO2NR''R''' wherein R'' and R''' independently are hydrogen or C1-6-alkyl, or CF3; or R<6> and R<7> together form an additional 4 to 7 membered ring which may be aromatic or partial saturated and which may be substituted with halogen, NO2, CF3, CN, SO2NR''R''' wherein R'' and R''' independently are hydrogen or C1-6-alkyl, and R<4> and R<5> have the meanings set forth above, are disclosed, as well as pharmaceutical compositions thereof. Certain of the compounds are novel. The compounds and pharmaceutical compositions containing the compounds are useful in the treatment of central nervous system disorders and especially conditions sensitive to excitatory amino acids.
Patent NZ-239151-A (NZ)
Title: Reclining chair with retractable foot support and intermediate convex mid-leg support
Inventor: BYERSMITH MICHAEL ROBERT
IPC: A47C1/0355
Filed: 1991-07-26
Abstract: A chaise lounge recliner chair (300) which incorporates an intermediate leg support member (312) for providing support to the thighs and areas behind the knees of the legs of an occupant of the chair. The intermediate leg support member (312) is connected to a portion of the seat (306) of the recliner chair and a portion of the leg rest member (310) of the chair. When the leg rest member (310) is in an extended position the intermediate leg support member (312) provides a normal slightly convex support surface. As the seat back (302) of the chair is reclined, it causes the seat member (306) to be extended outwardly which causes the intermediate leg support member (312) to assume a pronounced convex surface. A plurality of elastic straps (324) are further included and disposed between the seat (306) and leg rest members (310) to prevent the intermediate leg rest member (312) from crowning downwardly relative to the chair frame when the leg rest member (310) is in it extended position. <IMAGE>
Patent NZ-243995-A (NZ)
Title: Hair spray composition containing a fluorosurfactant
Inventor: PEFFLY MARJORIE MOSSMAN
IPC: A61K8/35
Filed: 1992-08-18
Abstract: The present invention relates to hair spray compositions useful for spray application to the hair comprising from about 0.01 % to about 2 % of an ionic fluorosurfactant, from about 0.1 % to about 15 % of an ionic resin and a liquid vehicle, wherein the hair spray compositions are characterized by utilizing silicone macromer containing hair setting resins and/or by containing relatively high amounts of water, i.e., water and higher. This invention also relates to hair spray compositions useful for spray application to the hair comprising from about 0.01 % to about 2 % of an ionic fluorosurfactant, from about 0.1 % to about 15 % of an ionic silicone macromer-containing hair setting resin, and a liquid vehicle. This invention further relates to hair spray compositions comprising from about 0.01 % to about 2 % of an ionic fluorosurfactant, from about 0.1 % to about 15 % of an ionic silicone macromer-containing hair setting resin, and a liquid vehicle, wherein the hair setting resin has a weight average molecular weight of at least about 300,000.
Patent NZ-261573-A (NZ)
Title: Process for the preparation of acyclovir (9-(2-hydroxy)-ethoxymethyl guanine)
Inventor: TURCHETTA STEFANO
IPC: C07D473/00
Filed: 1994-02-03
Abstract: PCT No. PCT/EP94/00308 Sec. 371 Date Mar. 7, 1996 Sec. 102(e) Date Mar. 7, 1996 PCT Filed Feb. 3, 1994 PCT Pub. No. WO95/07281 PCT Pub. Date Mar. 16, 1995A process for the preparation of acyclovir by alkylation of N2-formylguanine with 2-oxa-1,4-diacyloxybutane and hydrolysis of the resulting intermediate is described.\!
Patent NZ-275647-A (NZ)
Title: Tricyclic amide and urea derivatives and medicaments
Inventor: BISHOP W ROBERT
IPC: C07D401/04
Filed: 1994-10-12
Abstract: <CHEM>   <CHEM>   A method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells is disclosed. The method comprises the administration of a compound of formula (1.0) to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being. Novel compounds of formulae (5.0, 5.1, 5.2, 5.3, 5.3A and 5.3B) are disclosed. Also disclosed are process for making the 3-substituted compound of formulae (5.0, 5.1, 5.2 and 5.3). Further disclosed are novel compounds which are intermediates in the process for making 3-substituted compounds of formulae (5.0, 5.1, 5.2 and 5.3).
Patent NZ-279627-A (NZ)
Title: Article comprising poly(3-hydroxyhexanoate)copolymerised with a 3- or 4-hydroxycarboxylic acid
Inventor: NODA ISAO
IPC: A61L15/62
Filed: 1995-01-13
Abstract: The present invention relates to biodegradable PHA copolymers comprising at least two randomly repeating monomer units (RRMU) wherein the first RRMU has the structure   <IMAGE>   wherein R1 is H or C2 alkyl, and n is 1 or 2; the second RRMU has the structure   <IMAGE>   ; and wherein at least 50% of the RRMUs have the structure of the first RRMU. The present invention further relates to plastic articles comprising said biodegradable PHA copolymers. The present invention further relates to an absorbent article comprising a liquid pervious topsheet, a liquid impervious backsheet comprising a film comprising a PHA of the present invention and an absorbent core positioned between the topsheet and the backsheet.
Patent NZ-285404-A (NZ)
Title: Alpha-(pyrazol-3-yl)-oxymethylen-phenylbutenic acid methyl esters; pesticides and fungicides
Inventor: OBERDORF KLAUS
IPC: C07D231/08
Filed: 1995-04-25
Abstract: PCT No. PCT/EP95/01554 Sec. 371 Date Oct. 31, 1996 Sec. 102(e) Date Oct. 31, 1996 PCT Filed Apr. 25, 1995 PCT Pub. No. WO95/29896 PCT Pub. Date Nov. 9, 1995Methyl  alpha -phenylbutenoates of the formula I    <IMAGE>  I  where +E,uns --+EE  is a single or double bond and the index and the substituents have the following meanings: n is 0, 1, 2, 3 or 4; R1 is nitro, cyano, halogen, alkyl, haloalkyl or alkoxy; R2 is hydrogen, nitro, cyano, halogen, alkyl, haloalkyl, alkoxy, alkylthio or alkoxycarbonyl; R3 is unsubst. or subst. alkyl, alkenyl or alkynyl; an unsubst. or subst. saturated or mono-or diunsaturated ring which, in addition to carbon atoms, can contain one to three of the following heteroatoms as ring members: oxygen, sulfur and nitrogen, or an unsubst. or subst. mono- or binuclear aromatic radical which, in addition to carbon atoms, can contain one to four nitrogen atoms or one or two nitrogen atoms and an oxygen or sulfur atom or an oxygen or sulfur atom as ring members, processes for their preparation and their use are described.
Patent NZ-286400-A (NZ)
Title: 3-(benzofused azacyclic) substituted-2-oxo-1,3-oxazolidine derivatives and pharmaceutical compositions
Inventor: STOLLE ANDREAS
IPC: A61K31/655
Filed: 1996-04-18
Abstract: 2-Oxazolidinone derivs. of formula (I) and their tautomers, isomers and salts are new. R1 = N3, OH, OR2, OSO2R3 or NR4R5; R2 = 1-8C acyl or a protecting gp.; R3 = 1-4C alkyl or phenyl opt. substd. by 1-4C alkyl; R4 = H, 3-6C cycloalkyl, phenyl, 1-8C alkyl, 1-8C alkoxy or protecting gp.; R5 = as for R4 or COR6, PO(OR7)(OR8) or SO2R9; R6 = 1-8C alkyl, 2-8C alkenyl (both opt. substd. by CN, halo or CF3), H, opt. halo-substd. 3-6C cycloalkyl, CF3, 1-8C alkoxy, phenyl, benzyloxy, 1-6C thioalkyl, acyl, NR10R11 or 5-membered heteroaryl contg. 1-3 heteroatoms (S, N and/or O), opt. substd. by 1-3C alkyl; R10, R11 = H, phenyl or 1-6C alkyl; R7, R8 = H or 1-4C alkyl; R9 = 1-4C alkyl or phenyl; A = a gp. of formula (a); ring A is opt. substd.; X = CO, CS, SO, SO2, P(OH) or P(O)(OH); Y = O, S or NR13; R12, R13 = CONH2, NH2, NHSO2R, SO2NH2 or S(O)fR (all opt. substd.), 3-pyrrolidinyl, 4- piperidinyl (both opt. N-substd. by benzyl), 5-nitro-2-pyridyl, 2- or 4-pyridyl, COCCl3, 1-6C acyl (opt. substd. by CF3, CCl3, OH or (opt. aryl-substd.) 1-6C alkoxy); R = alkyl, phenyl, benzyl or tolyl; f = 0-2.
Patent NZ-296456-A (NZ)
Title: 6-aryl pyrido[2,3-d]pyrimidines and naphthyridines; inhibition of protein tyrosine kinase mediated cellular proliferation
Inventor: BLANKLEY CLIFTON JOHN
IPC: A61P43/00
Filed: 1995-11-13
Abstract: 6-Aryl naphthyridines are inhibitors of protein tyrosine kinase, and are thus useful in treating cellular proliferation mediated thereby. The compounds are especially useful in treating atherosclerosis, restenosis, psoriasis, as well as bacterial infections.
Patent NZ-297565-A (NZ)
Title: Separating light impurities from pulp suspensions: pulp fed into chamber containing rotor
Inventor: FREDRIKSSON BORJE
IPC: B04C7/00
Filed: 1995-11-13
Abstract: PCT No. PCT/SE95/01340 Sec. 371 Date May 22, 1997 Sec. 102(e) Date May 22, 1997 PCT Filed Nov. 13, 1995 PCT Pub. No. WO96/17998 PCT Pub. Date Jun. 13, 1996Apparatus for separating light impurities from a pulp suspension is disclosed. The apparatus includes a housing mounted on a fractionation device and symmetrically disposed with respect to the axis of rotation of the casing of the fractionation device, a passageway extending between the housing and the casing, and in which the top of the housing includes an outlet for the light impurities and a dilution liquid inlet for injecting dilution liquid tangentially into the housing.
Patent NZ-330093-A (NZ)
Title: Surface-structured bristles, process for producing the bristles and a brush or interdental cleaning device made from the bristles
Inventor: WEIHRAUCH GEORG
IPC: B29C48/16
Filed: 1996-08-22
Abstract: he invention pertains to a process for producing surface-structured synthetic bristle material by extrusion of a monofilament. Before or during extrusion, granules are added to a first thermally melted synthetic material which constitutes the principal component of the monofilament. The granules consist of a second synthetic material with a higher thermal stability than the first. The grain size of the granules is such that the monofilament when subsequently stretched undergoes a more marked transverse contraction in cross-sections with few or no granules than in cross-sections which have granules. The invention also pertains to a surface-structured bristle made from the principal component first synthetic material in which granules of the second synthetic material are embedded so as to be more or less completely covered and form a structure at the bristle surface. The invention further pertains to a brush, in particular a toothbrush or interdental cleaning device, with a plurality of bristles gathered as required into bundles, at least some of the bristles having the structure indicated above.
Patent NZ-332973-A (NZ)
Title: 1-Galactose derivatives which inhibit binding of toxins such as heat labile enterotoxin or cholera toxin
Inventor: HINDSGAUL OLE
IPC: A61P31/04
Filed: 1997-11-14
Abstract: Provided is a class of saccharide derivatives which inhibit the binding of toxins, such as heat-labile enterotoxin (LT) or cholera toxin (CT), to their receptors. The compounds also inhibit the binding of organisms, such as Vibrio cholerae and enterotoxigenic strains of Escherichia coli, to their cell surface receptors.  Specifically disclosed are  compounds of formula I: wherein A is arylene, cycloalkylene, cycloalkenylene, heteroarylene or a divalent heterocyclic B is cycloalkyl, cycloalkenyl and heteroscyclic Y is O, S, -S)O)-, and SO2 Y' is O, S, _S(O)-, _So2, alkylene and NR1 R1 is H, alkyl and acyl.