baber/WOPTO huggingface dataset:
Patent PT-1302205-E (PT)
Inventor: WADHWA HARDEEP
IPC: A61K9/22
Filed: 2002-10-01
Abstract: Disclosed is an oral controlled release macrolide pharmaceutical formulation. In a preferred embodiment, the formulation comprises a citrate salt of a preferred macrolide, clarithromycin. Also disclosed are methods for preparing, isolating and characterizing soluble and stable citrate salt of macrolides and use thereof in all solid dosage forms of macrolides.
Patent PT-1538202-E (PT)
Title: Production of human alpha-galactosidase a
Inventor: TRECO DOUGLAS A
IPC: A61P1/14
Filed: 1997-09-12
Abstract: The present invention provides a process for purifying human ±-galactosidase A (±-gal A) from a sample, wherein the process comprises a first chromatography step wherein the sample is passed over a hydrophobic interaction resin.
Patent PT-1576967-E (PT)
Title: Recombinant protein, carrying human papillomavirus epitopes inserted in an adenylate cyclase protein or fragment thereof, therapeutic uses thereof
Inventor: TIMMERMAN BENEDIKT
IPC: C07K14/025
Filed: 2004-03-18
Abstract: The invention relates to a recombinant protein comprising one or several polypeptides bearing one or several epitopes of one or several HPV antigens, said polypeptides being inserted in the same or different permissive sites of an adenylate cyclase (CyaA) protein or of a fragment thereof, wherein said CyaA fragment retains the property of said adenylate cyclase protein to target Antigen Presenting Cells.It also concerns polynucleotides encoding the same. The recombinant protein or the polynucleotide can be used for the design of therapeutic means against HPV infection or against its malignant effects.
Patent PT-1713830-E (PT)
Title: Anti-epcam immunoglobulins
Inventor: PETERS MALTE
IPC: C07K16/30
Filed: 2005-02-09
Abstract: The invention relates  inter alia  to a method of treating tumorous disease in a human patient by administering to the patient a human immunoglobulin specifically binding to the human EpCAM antigen, the immunoglobulin exhibiting a serum half-life of at least 15 days, the method comprising the step of administering the immunoglobulin no more frequently than once every week, preferably no more frequently than once every two weeks.
Patent PT-1781255-E (PT)
Title: Compositions and methods for treating leukemia
Inventor: THOMAS DEBORAH A
IPC: A61K9/127
Filed: 2005-08-09
Abstract: The present invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of leukemias, including acute lymphoblastic leukemia (ALL). The methods involve the administration of liposome-encapsulated vinca alkaloids, e.g., vincristine, in combination with dexamethasone to a mammal with a leukemia.
Patent PT-2071835-E (PT)
Title: Mobile virtual personal video recorder
Inventor: KNIGHT PHIL
IPC: H04N5/765
Filed: 2007-12-14
Abstract: Method for storage and/or access of records of television programmes, which are recorded by a personal video recorder (1),  characterised in that  the personal video recorder (1) is at least temporarily connectable to a server (3) using a communication channel (2) and that via said channel (2) the identity and other parameters of the recorded programme are transferred to the server (3) and stored as a dataset into a database (4). This programme identity information can them be used subsequently to allow access from a video on demand server to create a virtual PVR without the need for transfer of the actual streamed data in total.
Patent PT-1927356-E (PT)
Title: Low hygroscopic aripiprazole (crystal d) drug substance and processes for the preparation thereof
Inventor: BANDO TAKUJI
IPC: A61K31/496
Filed: 2002-09-25
Abstract: The present invention provides low-hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the aripiprazole anhydride crystals is stored for an extended period.
Patent PT-2248353-E (PT)
Title: Traveler`s alert system
Inventor: HEEN KJELL-HARALD
IPC: H04W4/90
Filed: 2009-02-19
Abstract: A method and a system for producing an updated status of users, associated with an MSISDN number in a mobile network, who are staying in a specific geographical area abroad, where it is desirable to be able to send information and warn of an undesirable event by sending a message to persons concerned.
Patent PT-693837-E (PT)
Inventor: BLOEM JACOBUS JOHANNES
IPC: H04L29/06
Filed: 1995-07-19
Abstract: The invention relates to a method of providing connections in a communications network, a connection being set up by a server in response to a service request from a client, the method comprising the steps of providing a representation (1;2;3) of a connection corresponding to the respective service request, and of establishing the connection on the basis of the representation. According to the invention the method is characterized in that the representation (3) comprises at least two levels of abstraction (1,2). This provides the possibility for the client to choose a suitably detailed representation of the connection. Preferably, only the representation having the highest level of abstraction (2) is initially offered to the client, the other representation (1) or representations only being presented upon request. <MATH>
Patent PT-756511-E (PT)
Inventor: HEIKKILA HEIKKI
IPC: C12F3/06
Filed: 1995-04-19
Abstract: PCT No. PCT/FI95/00224 Sec. 371 Date Oct. 18, 1996 Sec. 102(e) Date Oct. 18, 1996 PCT Filed Apr. 19, 1995 PCT Pub. No. WO95/29002 PCT Pub. Date Nov. 2, 1995The invention relates to a method for fractionating a solution by a chromatographic simulated moving bed method in which the liquid flow is effected in a system comprising at least two sectional beds in different ionic forms. The fractions enriched with different components are recovered during a multi-step sequence including the following operations, i.e., phases: feeding phase, eluting phase, and recycling phase. The liquid present in the sectional packing material beds with its dry solids concentration profile is recycled during the recycling phase in a loop comprising one, two, or more sectional packing material beds. The method can be employed for the following examples, fractionating sulphite cooking liquor, molasses, and vinasse.
Patent PT-803115-E (PT)
Inventor: SMEDING RIENK
IPC: G10D9/04
Filed: 1996-01-12
Abstract: The invention relates to a wind instrument comprising a basic body in which extends a central duct bounded by a peripheral wall of the basic body, a plurality of openings in the peripheral wall which connect the duct with the surrounding air, a number of valves mounted on the basic body and each comprising a closure member (5) coacting with an opening and comprising control means (49,52) connected to said valves, wherein said control means guide said closure member for movement between a closed position in which the opening is closed by said closure member and an open position in which the opening is left clear, wherein the closure member comprises a plate (16) of substantially stiff material which is provided on the side facing toward the opening with sealing material (18) and in the closed position engages round the opening and that the closure member is connected to the control means by yieldable means (52) and wherein the plate of substantially stiff material is connected to a rod (54) of said control means by means of an engagement element (49) fixedly mounted on the rod or forming part of said rod. Said engagement element extends from the centre of the plate in diverse directions over only a fraction of the radius of the plate. <IMAGE>
Patent PT-811001-E (PT)
Inventor: BERRYMAN KENT ALAN
IPC: C07D417/04
Filed: 1996-01-26
Abstract: Novel benzothiazine dioxides which are antagonists of endothelin are described, as well as novel intermediates used in their preparation, methods for the preparation, and pharmaceutical compositions of the same, which are useful in treating elevated levels of endothelin, essential renovascular malignant and pulmonary hypertension, cerebral infarction, cerebral ischemia, congestive heart failure, and subarachnoid hemorrhage.
Patent PT-870500-E (PT)
Title: Anti-helicobacter pylori agent
Inventor: YANAGI TOSHIHARU
IPC: A61P1/04
Filed: 1996-12-20
Abstract: A drug composition which comprises a combination of 4-Ä4-(4-methylbenzyloxycarbonyl)phenylÜphenyl trans-4-guanidinomethylcyclohexanecarboxylate or an acid addition salt thereof and a cyclodextrin, especially  beta -cyclodextrin, and is suitable for removing or exterminating Helicobacter pylori ; and a composite of the same.
Patent PT-818934-E (PT)
Inventor: ALEJO TREVIJANO JOSE JAVIER
IPC: H04N13/00
Filed: 1997-01-03
Abstract: The Invention is based on the use of the characteristic of LCD screens (1) which offer the possibility of directing the visibility angle of said screens as a function of the voltage applied. By directing said angle towards one eye or the other of the viewer alternatingly, as a function of previously recorded stereographic images and at a sufficiently high rate so that the viewer cannot perceive discontinuities, a tridimensional effect in the image received by said viewer is obtained. The block diagram of one of the invention includes an image generating system (2) connected to an LCD screen (1) and to an image synchronization block (3) which is connected to an angle generator system (4), the latter providing the necessary voltages to said screen (1) in order to direct the image from the screen to one of the other eye of the viewer.
Patent PT-912640-E (PT)
Inventor: SULLIVAN WILLIAM JOHN
IPC: C09C1/00
Filed: 1997-06-03
Abstract: A pearlescent pigment comprises C glass flakes having a first layer comprising rutile titanium dioxide or iron oxide thereon and a second layer comprising hydrous oxide or hydroxide of a polyvalent cation, precipitate of said polyvalent cation, and an anionic polymeric compound. A hydrous layer of the rutile forming titanium dioxide or iron oxide is first formed on the glass flakes and the resulting coated flakes are calcined prior to the application of the second layer.
Patent PT-919625-E (PT)
Inventor: IMLER JEAN-LUC
IPC: C12N15/12
Filed: 1994-05-27
Abstract: New replication-defective adenoviruses are selected from: (a) those that are derived from a natural adenovirus and lack at least the coding sequences of the E1B region and/or at least part of the E4 region; (b) those that are derived from a natural adenovirus other than a human type 5 adenovirus (Ad5) and lack part of the encapsidation region; (c) those that are derived from Ad5 and lack the part of the encapsidation region corresp. to nucleotides 270-346 in the Genbank M73260 sequence; and (d) those that are derived from Ad5 and lack the part of the encapsidation region corresp. to nucleotides 184-273 in the Genbank M73260 sequence. Also claimed is a eukaryotic cell contg. an adenovirus as above. Also claimed are: (1) a complementation line comprising a cell line contg. a complementation element which comprises at least part of the E1 region of a natural adenovirus and lacks the 5' ITR sequence, the element being integrated into the genome or inserted into a vector: and (2) a process for producing a defective adenovirus as above, comprising introducing the virus into a complementation line as above, culturing the cell line, and recovering the virus from the culture supernatant.
Patent PT-956313-E (PT)
Inventor: JOSEPH DIEPEN GARY VAN
IPC: C08G63/20
Filed: 1998-01-30
Abstract: A polymer blend comprising a polyester, a polyfunctional acid anhydride wherein said polyfunctional acid anhydride has a functionality as described herein of three or more, and a polyhydric alcohol or precursor thereto wherein said polyhydric alcohol has a functionality of three or more, and wherein said molar ratio of said polyfunctional acid anhydride to the polyhydric alcohol or precursor thereto is in the range of 0.5:1 to (10xC):1, where C is the number of moles of alcohol or equivalent in the polyhydric alcohol or precursor thereto.
Patent PT-1030785-E (PT)
Inventor: ZANARDI RODOLFO
IPC: B42D1/00
Filed: 1998-07-20
Abstract: The invention concerns a book structure which includes, assembled under one cover, a certain number of bound pages, some of which at least include leaflets with the dimensions exceeding those of the cover, with the external part of each section glued to corresponding adjacent leaflets and having, relative to the reading direction, at least one vertical folding line coinciding with the straight line of the book back to define the adjacent surfaces, and at least a horizontal folding line for covering the external element of the overlap of the lower and/or upper part of the coverings surface of the book cover.
Patent PT-1016507-E (PT)
Inventor: WATANABE HIDEYO
IPC: B25G1/00
Filed: 1999-02-02
Abstract: A knife (1) includes a blade (2) made of stainless steel and a hollow handle (4) made of stainless steel. The hollow handle (4) is comprised of right and left handle halves which are butt-joined to each other at their joining faces. The handle halves define therebetween a hollow portion which is filled with a filler, including river sand, for adjustment of overall weight balance of the knife. The blade and the handle are butt-joined into one piece at their confronting end edges. <IMAGE>
Patent PT-1080618-E (PT)
Title: Small culture motorised cultivating machine for private persons
Inventor: PUBERT JEAN-PIERRE
IPC: A01B33/00
Filed: 1999-09-03
Abstract: The power hoe has a plastic chassis (1) with work tools (2) rotatably mounted on a cross shaft. A motor (4) with a horizontal axis drives the tools via a chain drive with a step down ratio. The chassis is rectangular with the work tools on its upper face. The chain can be protected by a closed casing (30) extending across the chassis.
Patent PT-1054986-E (PT)
Title: Isolated and purified nucleic acids comprising a gene specifically expressed in hop glands
Inventor: OKADA YUKIO
IPC: C12N9/88
Filed: 1999-02-16
Abstract: An isolated and purified nucleic acid comprising a gene specifically expressed in hop lupulin glands. Hops are dioecious, and only female plants bear cones, the lupulin glands of which contain secondary metabolic products which provide bitterness and flavor to beer. These secondary metabolic products contain some pharmacologically effective compounds. In order to breed a more useful cultivar of hops by manipulating the constituent of such useful secondary metabolic products relying on genetic engineering techniques, this invention provides an isolated and purified nucleic acid comprising a gene specifically expressed in hop lupulin glands. By using this nucleic acid, it is possible to develop a novel method for breeding hops with transformation techniques and molecular selection techniques. Furthermore, the present invention also provides a nucleic acid comprising the regulatory region for specifically expressing genes in lupulin glands. This nucleic acid can be used also for hop breeding.
Patent SG-35594-G (SG)
Title: Hydrotreatment process
Inventor: INOUE YOSHIMASA
IPC: C10G45/04
Filed: 1994-03-10
Abstract: A process for hydrotreating a hydrocarbon oil contaminated with suspended solid particles and dissolved metallic compounds, comprising the contacting at an elevated temperature in the presence of hydrogen of the oil with porous inorganic oxide particles having a surface area of 1 m<2>/g or less and a pore volume of at least 0,1 ml/g in pores having a diameter of at least 10 microns,
Patent SG-64693-G (SG)
Title: Nicorandil-containing preparation for injection
IPC: A61K31/455
Filed: 1993-05-18
Abstract: A non-liquid type preparation for injection that has improved stability contains N-(2-hydroxyethyl)-nicotinamide nitrate ester (generally known as nicorandil) and an inorganic or organic acid and/or an alkaline metal salt thereof. These ingredients, together with an excipient that is pharmaceutically acceptable, may be dissolved in a solvent, sterilized by filtration and freeze-dried to obtain a freeze-dried preparation, or may be dissolved in a solvent under an aseptic condition and recrystallized to obtain an injectalbe powder. Nicorandil preparations according to the present invention are very stable and useful in clinical applications.
Patent SG-74489-G (SG)
Title: Compact electric apparatus powered by solar cells,in particular a solar watch
IPC: G04C10/00
Filed: 1989-11-16
Abstract: A small electric device powered by solar cells and by a capacitive charge storage element has stable actuation assured during startup with an as yet uncharged capacitor. Startup problems are avoided by control of the power supply with a threshold value circuit that allows power to be supplied to device components when the components' minimum actuating voltage level has been attained at the capacitor. A deactuating voltage value of the threshold value circuit that is lower than the actuating voltage level prevents interruptions of operation similar to relaxation oscillation behavior due to temporarily increased actuating power requirements by causing deactivation of the components only if the capacitor voltage has dropped below a predetermined operational minimum. In this manner additional functions (such as radio watches with automatic hands setting devices or directional antennas, or ornamental pendulums or alarm or striking watches) which have components with higher acutating power requirements may be supplied without batteries by solar cells without having to overdimension the storage capacitor for the high startup load and thereby unnecessarily delay actuation of the device upon the exposure to radiation of the solar cells.
Patent SG-78992-G (SG)
Title: Laminated metal sheet
IPC: B32B15/08
Filed: 1992-08-07
Abstract: A laminated metal sheet having adhered to one of its major surfaces a composite co-extruded polyolefin-containing film (B) comprising a plurality of layers in the following order:-   (B1) an inner layer of a bonding resin which is an acid modified polyolefin resin containing carboxyl or anhydride groups,   (B2) a layer of a polyolefin, (B3) a further layer of a bonding resin which is as defined for layer (B1), and   (B4) a layer of a polyamide.   The laminates of the invention are useful for forming into containers or various components therefor.
Patent SG-26373-G (SG)
Title: Clip attachment
Inventor: MARAFANTE GENTILE
IPC: A47L11/282
Filed: 1991-10-18
Abstract: The invention relates to a floor treatment operating disc (4) which can be engaged in a clip attachment with the drive plate (1) of a floor treatment device (G), having clip tongue passage windows (6) and a support surface (9) which is adjacent thereto and allows a gyratory movement between the drive plate (1) and the floor treatment operating disc (4). To achieve a solution which is, in particular, advantageous in use, the invention proposes that the support surface (9) is arranged on the outside of the clip tongue passage windows (6). 
<IMAGE>
Patent IE-780035-L (IE)
Title: Oxazolines
IPC: C07D505/00
Filed: 1978-01-06
Abstract: Useful intermediates for preparing a 1-dethia-1-oxacephalosporin and represented by the following formula: <IMAGE> (wherein R is a monovalent group resulting from the elimination of the carbonyl function of an acyl group derived from a carboxylic or carbonic acid; COB is carboxy or protected carboxy; and X is hydrogen or a nucleophilic group) are prepared from the corresponding penicillin 1-oxides of the following formula: <IMAGE> (wherein R, COB, and X are as defined above) by heating, if required in the presence of the desulfurizing reagent, or by exchanging the X group with another one under the condition of an appropriate nucleophilic substitution.
[US4220766A]
Patent IE-880100-L (IE)
Title: Dietary fiber and method of making
IPC: A23L33/20
Filed: 1988-01-14
Abstract: An extremely white water absorbent fiber having a high percentage of total dietary fiber and hemicellulose and a low concentration of lignin and silica is disclosed. The dietary fiber is formed by subjecting ground oat hulls to an alkaline digestion at elevated temperatures and pressures. The digested oat hulls are then filtered, neutralized and bleached to form the desired end product. The formed fibers are comparable or better than fibers formed by digestion of wood products. These fibers can be added in high concentrations to bakery products, particularly bread, without imparting a gritty feel to the bread or causing significant discoloration of the bread.
Patent IE-810250-L (IE)
Title: N-(3-phenoxy-2-hydroxypropyl) benzimidazole -1-¹alkanamines.
IPC: C07D473/00
Filed: 1981-02-10
Abstract: 3-Phenoxy-2-hydroxypropylamines having an N-benzimidazolyalkyl substituent and similar compounds are described herein. They are obtained by the reaction of the appropriate imidazole-1-alkanamine with an epoxide, and they are useful primarily as beta -adrenergic blocking agents.
[US4363808A]
Patent IE-44462-L (IE)
Title: 1, 2-dithiole derivatives
IPC: C07D339/00
Filed: 1977-02-09
Abstract: 1,2-Dithiole derivatives of the formula: <IMAGE> wherein Het represents a pyridazin-3-yl radical, or a pyrimidin-2-yl, -4-yl or -5-yl radical, each such radical being optionally substituted by a halogen atom or by an alkyl radical of 1 through 4 carbon atoms, an alkoxy radical of 1 through 4 carbon atoms, the mercapto radical, an alkylthio radical of 1 through 4 carbon atoms or a dialkylamino group having 1 through 4 carbon atoms in each alkyl radical, are new compounds useful in the treatment of bilharziasis and amoebiases.
[US4104386A]
Patent IE-39061-L (IE)
Title: Toothbrush
IPC: A46B11/00
Filed: 1974-03-15
Abstract: 1470268 Reservoir toothbrushes TRISA BURSTENFABRIK AG 21 March 1974 [21 March 1973 7 Jan 1974] 12679/74 Heading A4K Movement of a dentifrice cartridge 30 towards the brush head 33 of a reservoir toothbrush against the action of a spring 36 causes dentifrice to be delivered to the bristles through a duct 32, in a piston 37 and a duct 12, 19 in the brush head, leakage of dentifrice being prevented by providing part of the duct in the brush head with a diameter sufficient to exert a capillary effect on the dentifrice. Preferably such a diameter is between 0À5 and 1À5 mm and is provided in that part 19 of the duct which opens into the bristles. The non- capillary part of the duct may be 2 mm. The cartridge and handle may be of rectangular cross-section with the handle having sloping side walls (41a, 41b) Figs. 3-5 (not shown) which abut against correspondingly sloping shoulders (40a, 40b) on the cartridge.
[GB1470268A]
Patent IE-780756-L (IE)
Title: Plant propagating bodies
IPC: A01G9/10
Filed: 1978-04-18
Abstract: The plant propagating body comprises a plurality of connected parallel tubular foamed polystyrene containers 3. The containers 3 are connected together by a web 2 which is integrally moulded with the containers 3. The containers 3 each have a top opening 3a and a bottom opening 3b. The interior of each container 3 is occupied by a non-toxic porous or fibrous plug 5 which has a plurality of interstices some of which are of capillary dimensions. The plant propagating body has particular application in the propagating of a seed - placed on top of the plug 5 for example - to a seedling which may then be transplanted in a hydroponic module or transplanted to a more conventional horticultural medium such as soil. <IMAGE>
[GB2018557A]
Patent IE-890810-L (IE)
Title: Pharmaceutical formulations for parenteral use
IPC: A61K9/08
Filed: 1989-03-14
Abstract: Aqueous parenteral solutions of drugs which are insoluble or only sparingly soluble in water and/or which are unstable in water, combined with a hydroxypropyl, hydroxyethyl, glucosyl, maltosyl or maltotriosyl derivative of B- or .gamma.-cyclodextrin, provide a means for alleviating problems associated with drug precipitation at the injection site and/or in the lungs or other organs following parenteral administration.
[CA1336498C]