baber/WOPTO huggingface dataset:
Patent HU-192711-B (HU)
Title: With mercury filled holder for introducing mercury charge of low-pressure mercury vapour discharge lamp into the discharge lamp
Inventor: KUIJER WILLIAM L
IPC: H01J61/28
Filed: 1985-05-15
Abstract: A method of manufacturing a mercury vapour discharge lamp, in which use is made of a lamp vessel (1) provided with an exhaust tube (6), the quantity of mercury required for the operation of the lamp being present in metallic form in a closed for the major part plate-shaped metal container (5) which is arranged in the exhaust tube and is held in place by a waisted portion (7) in the container and a corresponding rib (8) in the exhaust tube, in which method the container, after evacuation of the lamp, is heated so that it opens due to the mercury vapour pressure building up in it. According to the invention, a centrally arranged hole (14) is provided in the plate-shaped part of the container between the waisted portion (7) and the end.
Patent HU-204639-B (HU)
Inventor: SZEKERES GABOR
IPC: H04M1/64
Filed: 1989-04-14
Abstract: A találmány tárgya kapcsolási elrendezés hangfrekvenciás analóg jelek tömörítésére és feldolgozására, különösen üzenetrögzítési célokra, amely kapcsolási elrendezésben központi időzítő-áramkör (10) illesztőáramkörre (11) csatlakozik, továbbá a központi időzítő-áramkör (10) és az illesztőáramkör (11) adatbusszal (12), előnyösen számítógép adatbuszával (12) van kétirányú kapcsolatban. A találmánynak az a lényege, hogy -   a központi időzítő-áramkör (10) további kimenetei kődoló-dekódoló áramkör (4) órajelbemeneteire csatlakoznak, amely -   kódoló-dekódoló áramkörnek (4) hangfrekvenciás bemenete és hangfrekvenciás kimenete van, továbbá -   a kódoló-dekódoló áramkör (4) PCM-kimenetei illesztőáramkör (11) további bemenetelre, míg -   a kódoló-dekódoló áramkör (4) PCM-bemeneteire az illesztőáramkör (11) további kimenetei csatlakoznak.  8   9 HU 204 639 B A leírás terjedelme: 4 oldal (ezen belül 1 lap ábra)
Patent HU-183190-B (HU)
Inventor: ZAITSEV ANATOLY G
IPC: B65B35/00
Filed: 1980-07-29
Abstract: A találmány tárgya berendezés tartályfedélnek fedélhalmazról való egyenkénti levételére, amelynek háza, fedéltárolója és reteszelőszerve van. A találmány szerinti berendezés újdonsága abban van, hogy a reteszelőszerkezetnek egy pár vízszintesen elrendezett csuklósán rögzített rugókkal rendelkező kétfogú villái vannak, amelyeknek egyik foga a másik foghoz képest a függőleges síkban eltolva van elhelyezve; és hogy a kétfogú villák egymáshoz képest úgy helyezkednek el, hogy egy kétfogú villa felső foga a másik kétfogú villa alsó foga fölött helyezkedik el; továbbá hogy a kétfogú villák alsó fogai ütközőkkel rendelkeznek. A találmány szerinti berendezést főleg az élelmiszeriparban alkalmazhatjuk igen előnyösen tartályfedeleknek fedélhalmazból egyenként való levételére. A találmány szerinti berendezés a tartályfedeleknek fedélhalmazból való levételét külön hajtómű alkalmazása nélkül teszi lehetővé.  -1-
Patent HU-186416-B (HU)
Inventor: SIGIHARA HIROSADA
IPC: C07D307/94
Filed: 1980-04-30
Abstract: Λ találmány tárgya eljárás (I) általános képietű spiro-benzofuranonok előállítására, oly módon, hogy egy (Π) általános képietű vegyületet redukálunk. Az (I) általános képletü új vegyületek gyomorszekréciót gátló, gyulladásgátló és analgetikus hatásúak
Patent HU-198851-B (HU)
Inventor: MARIK JANOS
Filed: 1984-07-12
Abstract: A találmány tárgya berendezés sókiválásra hajlamos termálvizek, főként uszodai termálvizek szűrésére a gravitációval ellenáramban. 5 A találmány szerinti berendezésnek alulról fölfelé csökkenő méretű szemcsés anyagból álló szűrőágyat (1) befogadó szűrőtartálya (2), a szűrőtartály (2) alján elrendezett elosztókamrája (3)) és perforált vizbevezető 10 aljzata, szűrtvízelvezető rendszere, valamint a szűrendő folyadékot a szűrőágy (1) alá juttató, legalább egy szivattyúja (6) van, amely berendezés sajátossága az, hogy a szűrőtartály (2) legalább négy, vagy ennek 15 többszörösét kitevő .számú részegységre (2a, 2b) van felosztva és négy ilyen részegységhez egy közös elosztókamra (3) és két, a szűrendő folyadékot a szűrőágy (1) alá juttató szerkezet, célszerű szivattyú (6) van 20 társítva, ahol a perforált vizbevezető aljzat a középen elrendezett elosztókat»rabol (3) kiinduló és a részegységek (2a, 2b) alján átmenő kívülről kihúzható perforált elosztócsövekből (4) van kialakítva, míg az elosztókamra (3) 25 oldalába legalább egy tangenciálisan elhelyezett, vízbevezető gyorsító fúvóka (7) van beépítve. A találmány szerinti berendezésnél szűréskor mind a négy részegységbe egyetlen 30 szivattyúval juttatjuk be a vizet, míg mosáskor egy szivattyúval egy részegységet, a szemcseszerkezet visszarendezésekor pedig két szivattyúval egyetlen részegységet szolgálunk ki, amikoris a megnövelt sebességű, adott esetben recirk ulációban tartott vízzel a szemcsés szóróanyagot fluid állapotba hozzuk és az egymáshoz dörzsölódő szürőanyag-szemcséket, az igy fellépő koptató hatás révén megtisztítjuk. (1. ábra)  HU 198851 A A leírás terjedelme: 4 oldal, .7 rajz., .7 ábra -1-
Patent HU-205191-B (HU)
Title: Joint structure for doors and windows particularly furniture-doors
Inventor: PRODAN MARINO
IPC: E05D11/10
Filed: 1990-05-24
Abstract: The furniture hinge, particularly a cup-hinge, comprises a stationary hinge arm (1) adjustably fastened, as to its location, on a base plate (11), a swingable hinge cup (2), a pair of connecting pivot levers (3, 4), which pivotably connect the cup (2) and the arm (1), and a spring assembly (14) placed in the clearance of the box-shaped arm (1). Between a control cam (5) of the inner pivot lever (4) and a disc-shaped insertion (19) of a pressure spring (8) of the spring assembly 14, there is inserted a transmission pin (7), which is held and guided by slots (6 min ) that are arranged in the side walls of the housing (6) of the spring assembly (14) and are situated slantingly with respect to the axis of symmetry of the spring (8).
Patent HU-205300-B (HU)
Title: Swinging push door for vehicles
Inventor: GOLDBACH HORST
IPC: B61D19/00
Filed: 1990-06-01
Abstract: The swingable sliding door has one or two door leaves (3, 4) arranged in the closed state on the outside in the vehicle wall, which leaves are to be guided on guide rails (35, 36) and in a telescopic guide (5) and to be actuated with the aid of a drive device (24, 33, 37). 
<??>In addition, swivel levers (12, 13) and control levers (14, 15) are provided which swivel the door leaves out of the vehicle body plane and participate in the locking in the closed state. 
<??>An electric motor gearing unit (33, 37) whose drive disc (24) drives the door leaves (3, 4) by means of a deflection disc (25) and a pulling means (23) is provided as drive. The flange (19) of the drive unit is swivelably mounted and bears a control pin (17) which swivels the door in and out via the control lever (15) and locks in a dead-centre position in the closed state. 
<IMAGE>
Patent HU-194657-B (HU)
Inventor: BIHARI GYOERGY
IPC: H02M7/48
Filed: 1985-09-24
Abstract: A találmány tárgya kapcsolási elrendezés kapcsolóüzemű tápegység vezérlő impulzus aszimmetriájának korlátozására, amelynek lényege, hogy vezérlő egységének (1) első kimenete (11) időzítő egység (2) első bemenetére (21) és kapcsoló egységének (3) első bemenetére (31), második kimenetc (12) az időzítő egység (2) második bemenetére (22) és a kapcsoló egység (3) második bemenetére (32) csatlakozik, az időzítő egység (2) kimenete (23) a vezérlő egység (1) tiltó bemenetéhez (13) van csatolva.  lábra -1-
Patent HU-199064-B (HU)
Title: Compositions determining growth of plants containing 1-/methyl-amino/-cyclopropane-1-carboxylic acid derivatives as active components and process for producing 1-/methyl-amino/-cyclopropane-1-carboxylic acid derivatives
Inventor: LUNKENHEIMER WINFRIED
IPC: A01N53/00
Filed: 1984-09-28
Abstract: 1. Methylamino-cyclopropan-1-carboxylic acid derivatives of the formula   see diagramm : EP0136615,P17,F1   in which X represents hydroxyl, or alkoxy which has 1 to 18 carbon atoms and is optionally substituted by hydroxyl, halogen, amino, alkylamino having 1 to 4 carbon atoms, dialkylamino having 1 to 4 carbon atoms per alkyl group, N-acylamino, alkoxy having 1 to 4 carbon atoms, acyloxy, cycloalkyl having 3 to 7 carbon atoms and/or phenyl, or represents amino or alkylamino having 1 to 4 carbon atoms and y represents hydrogen or formyl, and their plant-tolerated acid addition salts.
Patent HU-194771-B (HU)
Inventor: CZAKO ATTILA
IPC: B60G11/24
Filed: 1985-11-21
Abstract: A találmány járművekhez, vagy rázkódásnak kitett szerkezetekhez megoldott felfüggesztés, mely önáiló rugózó egységként párhuzamos lengőkarok által kapcsolódik a jármű vázszerkezetéhez. A rugózást a két lengőkar (3) közé fogott, nyírásra igénybe vett fémlapok közé vulkanizált gumirugó (1) látja el, mely a fémlapok segítségével, csavarkötéssel kapcsolódik a hossz-vagy keresztirányú lengőkarokhoz (3). A gumirugó Shore keménysége előnyösen 45-70. (2. ábra).  -1-
Patent HU-200465-B (HU)
Title: Process for producing substituted alphaamino acids, derivatives thereof and pharmaceutical compositions comprising such compounds
Inventor: HERRLING PAUL LINUS
IPC: A61P25/28
Filed: 1987-10-16
Abstract: Substituted  alpha -amino acids useful for treating epilepsy, disorders associated with excess GH or LH secretion, anxiety, schizophrenia, depression, CNS degenerative disorders, cerebral hypoxic conditions and stress-related psychiatric disorders: are alpha -amino- alpha -(3-alkylphenyl) alkyl-ethanoic acids or esters or amides thereof, in which the 3-alkyl moiety bears a phosphorus oxo acid group or an ester thereof, wherein phosphorus is attached directly to the alkyl moiety, or salts thereof. The compounds may have the formula:-   <IMAGE> wherein R1 R1, R2, R3, Y, m and n have certain defined meanings, Y being linked via a phosphorus atom.
Patent HU-197621-B (HU)
Inventor: BERNDT ROBERT
IPC: F01M9/00
Filed: 1986-12-09
Abstract: Die Erfindung bezieht sich auf die Schmieroelfoerderung fuer einen Kompressor und einen daran angeschlossenen Elektromotor, die als kompakte Baueinheit in einem hermetisch geschlossenen Gehaeuse angeordnet sind. Erfindungsgemaess ist der bereits bekannte, kegelige Rohransatz 6 zwischen dem Oelspiegel des Oelsumpfes 8 und dem Anschlusspunkt an der Welle des Elektromotors 4 mit mindestens einer den Querschnitt der Oelfuehrung 9 lokal verengenden und den in der Oelfuehrung 9 gefoerderten Oelfilm 14 unterbrechenden Sicke 12 versehen, die an der zur Laengsachse des Rohransatzes 6 engsten Stelle eine Durchgangsbohrung 13, die den Innenraum des Rohransatzes 6 mit dem Innenraum des Gehaeuses 3 verbindet, aufweist. Fig. 1
Patent HU-209740-B (HU)
Title: Process for separating polymer solids from polymerization slurry
Inventor: HOTTOVY JOHN DOUGLAS
IPC: C08F6/10
Filed: 1990-08-30
Abstract: A polymerization process wherein monomers are polymerized in liquid diluent to produce a liquid slurry containing particles of normally solid polymers, periodically opening a product takeoff port to allow a charge of liquid slurry to flow into an elongated confined zone including a flash line heater and then into a flash chamber wherein the lighter components are separated from the polymer The process is particularly characterized by the fact the elongated confined zone is constructed such that the flow time of the charge of slurry in the flash line heater is equal to at least about 25 percent of the time between the time of the closing of the settling valve and the next opening of the settling valve.
Patent ID-830-B (ID)
Inventor: ARTHURSON CRAIG JOHN
IPC: B01J19/12
Filed: 1992-01-31
Abstract: PCT No. PCT/AU90/00280 Sec. 371 Date Dec. 24, 1991 Sec. 102(e) Date Dec. 24, 1991 PCT Filed Jun. 29, 1990 PCT Pub. No. WO91/00242 PCT Pub. Date Jan. 10, 1991.An ozone generator (1) comprises an ultra-violet lamp (2), means (3, 12, 13) for directing a flow of an oxygen containing gas through a zone (16) in which the gas is exposed to ultra-violet radiator emanating from the lamp, and means (8, 9) to expose the gas to a high voltage, low current electric field prior to or during exposure to ultra-violet radiation. Preferably at least one magnet 15 is associated with lamp 2 so that ionized particles within the lamp are concentrated by a magnetic field to congregate in a localized region in the vicinity of the zone (16).
Patent IT-1233390-B (IT)
Title: Machine for cutting food
Inventor: CAMPA UGO
IPC: B26D/
Filed: 1989-03-01
Granted: 1992-03-27
Abstract: The machine comprises upper (13) and lower (14) cutting elements mounted one above the other on a common axis, and rotated in opposite directions. A feed chute is provided together with an impeller for supplying the food to the cutting elements. A hopper receives the cut food and can discharge it to a conveyor. The upper cutter (13) is a disc provided with radial slots (11) and teeth (11') on its upper surface (38). The lower cutter (14) comprises a blade supported by a ring. The upper cutter (13) has gear teeth (12) engaging a driven gear and idler gears, and the lower cutter has gear teeth (14') engaging a driven gear and idler gears, the upper and lower cutters being driven by separate motors.
Patent LV-13441-B (LV)
Title: A method for the preparation of enantiomercally pure mirtazapine
Inventor: WIERINGA JOHANNES HUBERTUS
IPC: C07D471/14
Filed: 2006-02-10
Abstract: The invention provides a method for the preparation of enantiomerically pure mirtazapine, said method comprising a step of ring closure of a compound of formula (II) wherein X is a leaving group, said step comprising treatment with an acid, whereby mirtlazapine with enantiomeric excess is formed by the ring closure of the compound of formula (II) with enantiomeric excess by treatment with a suitable acid in the absence of a solvent or a suitable combination of an acid and an organic solvent.
Patent LV-10499-B (LV)
Inventor: MICHAEL JARSCH
IPC: C12N15/70
Filed: 1993-06-02
Abstract: Aparakstīta rekombinantā glikozes-6-fosfāta dehidrogenāze, kas raksturojas ar SEQ ID NO: 1 secību,
un tās iegūšanas paņēmiens. Rekombinanto vektoru, kas satur glikozes-6-fosfāta dehidrogenāzes gēnu,
izmanto E.coli transformēšanai, transformēto baktēriju kultivē un izdala vajadzīgo fermentu no kultūrvides vai
šūnām.
Patent LV-10474-B (LV)
Title: Alfa-cyanacrylate adhesive compositions
Inventor: GERHARD WENZ
IPC: C09J4/00
Filed: 1993-06-28
Abstract: PCT No. PCT/EP91/00517 Sec. 371 Date Nov. 17, 1992 Sec. 102(e) Date Nov. 17, 1992 PCT Filed Mar. 18, 1991 PCT Pub. No. WO91/14749 PCT Pub. Date Oct. 3, 1991.The setting properties of an  alpha -cyanoacrylate adhesive composition are accelerated by adding thereto a hydroxyl group derivative of an  alpha -,  beta - or  gamma -cyclodextrin which is at least partly soluble in the  alpha -cyanoacrylate.
Patent LV-11170-B (LV)
Title: Device for contact tempering of show-windows' glass sheets
Inventor: VANASCHENN LUC
IPC: C03B27/00
Filed: 1993-12-28
Abstract: This proposed device (Fig. 1) contains two contact cooling - compression plates (1,2) and collectors, positioned on their periphery (20) for air blasting through the nozzles (22). In order to avoid deformation and warping of the glass sheet, air blasting collectors (20) are positioned in the form of parallel sides, which are placed between the nozzles, while the cross - section is at least three times larger than the nozzle (22) cross - section, and the distance from nozzle (22) openings to the surface of the glass sheet sides equals two to six diameters of the openings. Several versions of implementation are proposed for the invention, which differ in the reciprocal placement and equipment of nozzles (22) and positioning of contact cooling and compression plates (1,2). For instance, one contact cooling and compression plate (2) is manufactured from metal and tightly fastened, while the other (1) is formed as a metal box (11), covered by an elastic membrane (12), while cooling water is pumped into it under pressure. The plate (2) is equipped with a coating in the form of an elastic flexible layer (7) with the heat conductivity resistance 0.1x10<-3> - 0.25x10-<3> m<2>kW<-1>.  The membrane is formed from an elastic deformable polytetrafluoroethylene film (16), the thickness of which is 0.1 - 0.4 mm and heat-conductivity resistance is 0.25x10<-3> - 5x10<-3>  m<2>kW<-1>, whereas the outer surface is covered by a metal plate (17).<IMAGE>
Patent ME-00959-B (ME)
Inventor: DUCREY BERTRAND
IPC: A61K47/34
Filed: 2008-06-06
Abstract: Farmaceutska kompozicija napravljena od mikročestica za sporo oslobađanje aktivne supstance najmanje tokom perioda koji pokriva šesti mesec posle injektiranja navedene kompozicije, pri  čemu  navedena kompozicija sadrži grupu  mikročestica napravljenih od kopolimera PLGA tipa koji sadrži aktivnu supstancu u obliku peptidne soli koja je nerastvorljiva u vodi; pri čemu navedeni kopolimer pored toga sadrži najmanje 75% mlečne kiseline i ima viskoznost između 0.1 i 0.9 dl/g, kao što je mereno u hloroformu na 25°C i pri koncentraciji polimera od 0.5 g/dL; navedene mikročestice pored toga imaju raspodelu veličine defmisanu na sledeći način: -D (v, 0.1) je između 10 i 30 mikrometara, - D (v, 0.5) je između 30 i 70 mikrometara, - D (v, 0.9) je između 50 i 110 mikrometara.
Patent NO-161207-B (NO)
Inventor: HAPPEL JOHN
IPC: B01J23/22
Filed: 1983-09-29
Abstract: Disclosed is a process which comprises calcining an intimate mixture of elemental sulfur and compounds of the other elements in the following empirical atomic formula and further treating the resulting mass to obtain the new catalyst:wherein:X is a transition element or a mixture thereof selected from the group V, Mo, W;Y is a stability enhancing element or a mixture thereof selected from the group C, Si, B, Ce, Th, Nb, Zr, Ta, U, where «a» can vary from 0 to 2;Z is a promoter element or a mixture thereof selected from the group Co, Ni, Fe, where «b» can vary from 0 to 0.1;S is the element sulfur, where «c» can vary from 1.3 to 6.0;O is the element oxygen, where «d» can vary from 0 to the upper limit required by stoichiometry.
Patent NO-166207-B (NO)
Inventor: LAWSON LESLIE EDWARD
IPC: G03F7/26
Filed: 1983-10-20
Abstract: Changes occurring in the electrical conductivity of liquids used to process image-wise exposed radiation sensitive devices are used as a measure of the deterioration in effectiveness of the liquids. This deterioration is compensated for by varying the processing conditions, such as temperature, time, scrubbing action and processing liquid composition, in accordance with the change in conductivity.
Patent NO-163631-B (NO)
Inventor: MOLDENIUS STEVE
IPC: D21C9/16
Filed: 1984-08-15
Abstract: PCT No. PCT/SE83/00462 Sec. 371 Date Aug. 17, 1984 Sec. 102(e) Date Aug. 17, 1984 PCT Filed Dec. 16, 1983 PCT Pub. No. WO84/02366 PCT Pub. Date Jun. 21, 1984.A method of peroxide bleaching lignocellulose-containing material for providing a pulp of both high strength and brightness. Increase in strength is provided in a first stage by hyper-alkaline peroxide bleaching known per se, i.e. bleaching carried out at an initial pH of over 12, measured in the bleaching liquid at 24 DEG  C. before mixing into the pulp. The desired brightness increase is provided in a subsequent stage with or without intermediate washing of the pulp and at a lower initial pH.
Patent NO-167639-B (NO)
Inventor: MARBACH KARL
IPC: B26D7/18
Filed: 1987-09-04
Abstract: In a strip steel punch tool with a supporting plate (1), wherein strip steel punch cutters (3) projecting beyond the surface (8) of the supporting plate (1) are held in slots (2) and profiled strips (7, 7') made of resilient material, preferably rubber, cellular rubber, rubber cork or the like, are fastened to the supporting plate (1) in parallel and next to the said cutters, these profiled strips protruding above the cutting edge (6) of the strip steel punch cutters (3) with their punching material contact face (9), it is proposed, in order to punch clean edges especially in large numbers, that the profiled strip (7, 7') be constructed such that, when loaded vertically, its punching material contact face (9) is displaced towards the strip steel punch cutter (3). <IMAGE>
Patent NO-166598-B (NO)
Inventor: KAESER RUDOLF
IPC: C06B21/00
Filed: 1988-06-16
Abstract: A water-filled pressure chamber (7) loaded by conventional pumps at pressures of several thousand bars is used to isostatically press explosive charges. Inside this pressure chamber (7) is a compression mold (6) having an inner/outer mold (1) consisting of several components. Explosives in the mold are subjected through an elastic sleeve (3) to liquid pressure (p), so that the interior pressure in the chamber will be nearly isostatic. Following pressure relief, Dimensionally accurate and homogeneous precision explosive charges are obtained. The present invention also includes the process using the pressure chamber. The invention increases manufacturing output and quality of explosive charges so produced.
Patent NO-178152-B (NO)
Inventor: HAVAS LASZLO
IPC: C08F210/16
Filed: 1991-08-06
Abstract: The present invention relates to a process for stopping an olefin polymerisation which is carried out in a low pressure gas phase reactor, which process comprises introducing an effective quantity of deactivating agent into the reactor, characterised in that the olefin polymerisation is carried out using a chromium oxide catalyst and in that the deactivating agent is selected from oxygen, ammonia, water and carbon monoxide and is introduced over a relatively short period of time. The deactivating agent is preferably introduced into the polymerisation reactor in a quantity such that in the reactor the weight ratio of the deactivating agent to the catalyst is at least 0,001.
Patent SE-372878-B (SE)
Inventor: BORGGREN K
IPC: A47C31/04
Filed: 1972-03-14
Abstract: In a seating furniture or seat each opposite marginal portion of a flexible seat or back supporting element is secured to a ledge having a groove diverging outwardly in relation to the longitudinal middle plane of the piece of furniture and seat, respectively, said ledge being detachably mounted in and complementary to a recess in the frame of the furniture or seat, respectively.
Patent YU-47208-B (YU)
Inventor: CORAL L
IPC: B01D46/02
Filed: 1989-06-07
Abstract: The air in which the oil particles are suspended is drawn from the environment through an air intake (4) as a result of the vacuum created by induction means (11) and then passes along a substantially vertical duct (5) in which an internal helical element (6) causes the mechanical separation of the oil particles by centrifugal action due to the rotation of the air imparted by the helix, the oil particles collecting on the wall of the duct (5) from which they drain into a collecting hopper (2), after which the air is further filtered by additional filtering means (9, 10) before reaching the delivery opening (13).
Patent YU-43721-B (YU)
Title: Process for additioning mixed fertilizers with methionine
Inventor: TNNNER H
IPC: A23K1/18
Filed: 1981-11-22
Abstract: In place of using solid DL-methionine for supplementing mixed fodders there are used sodium or potassium methioninate solutions. In comparison to solid methionine they are more easily dosable and can be more easily homogeneously mixed with the remaining components. Employing equimolar amounts they show the same methionine activity as solid methionine.
Patent ZA-841840-B (ZA)
Title: Tropone derivatives,processes for preparation thereof and pharmaceutical compositions comprising the same
Inventor: UEDA IKUO
IPC: C07D279/02
Filed: 1984-03-12
Abstract: A compound of the formula; 
<CHEM>
 wherein R<1> is hydrogen or lower alkyl,
 R<2> is hydrogen, hydroxy, halogen, lower alkyl or lower alkoxy, and
 R<3> is hydrogen or acyl,
 and pharmaceutically acceptable salts thereof, processes for their preparation, and pharmaceutical compositions comprising them as an effective ingredient, in association with a pharmaceutically acceptable, substantially nontoxic carrier or excipient.