baber/WOPTO huggingface dataset:
Patent ES-8500060-A1 (ES)
Title: Stabilized insulin preparations
IPC: H05K13/06
Filed: 1983-02-04
Abstract: Novel pharmaceutical solutions of dissolved insulin having improved physical stability prepared by incorporating therein an essentially ionized zinc salt in a concentration corresponding to a content of zinc ions at the disposal of the insulin of more than 4 Zn2+/hexamer insulin preferably 4.2-4.5 Zn2+/hexamer insulin. The solutions exhibit a stability factor exceeding 5. The novel insulin solutions are particularly adapted for use in continuous insulin delivery equipment.
Patent ES-8405010-A1 (ES)
Title: Alpha-formamido-substd. beta-lactam cpds.
IPC: C07D501/48
Filed: 1983-03-24
Abstract: Beta-lactam antibiotics (I) having an alpha-formamido substit. on the C atom adjacent to the CO gp. of the ring are new. They are esp. cpds. of formula (II) or their salts. In (II), R1 is H, an acyl gp. or an amino-protecting gp.; R2 is H or a readily removable carboxyl-protecting gp.; Y is -S-CMe2-, -S-CH2- or -Y1-CH2-CZ: Y1 is O, S or CH2; Z is H, halogen or an organic gp. such as 1-4C alkoxy, CH2Q or CH:CHQ; and Q is H, halogen, OH, SH, CN, COOH, carboxylic ester, 1-4C alkoxy, acyloxy, aryl, heterocyclyl bonded via a C atom, hetercyclylthio or a N-contg. heterocyclyl bonded via a N atom. Cpds. (I) are broad-spectrum antibacterials, esp. when R1 is acyl in cpds. (II), and they have esp. good activity against Gram-negative bacteria and are useful as therapeutic agents in man and animals. Other cpds., esp. (II; in which R1 is H or a protecting gp.) are intermediates in the prepn. of the N-acyl derivs.
Patent ES-8505975-A1 (ES)
Title: Pesticides.
IPC: A01N43/80
Filed: 1983-11-25
Abstract: The invention relates to the use of 3-acylaminobenzisothiazole-S,S-dioxides of the formula I < IMAGE > (I) wherein R1 is C1-C10alkyl, phenyl, or C1-C10alkyl which is substituted by halogen or C1-C5alkoxy, and R2, R3, R4 and R5 are each independently hydrogen, halogen, C1-C5alkyl, C1-C5alkoxy, trifluoromethyl, amino or nitro, for controlling insects and representatives of the order Acarina. The invention further relates to novel compounds of the formula I, wherein R1 is C1-C10alkyl, phenyl, or C1-C10alkyl which is substituted by halogen or C1-C5alkoxy, and R2, R3, R4 and R5 are each independently hydrogen, halogen, C1-C5alkyl, C1-C5alkoxy, trifluoromethyl, amino or nitro, with the proviso that R2, R3, R4 and R5 are not at the same time hydrogen, as well as to the preparation of these compounds and to pesticidal compositions containing them.
Patent ES-8600376-A1 (ES)
Title: Detergent compositions.
IPC: C11D1/12
Filed: 1984-01-20
Abstract: Detergent compositions suitable inter alia for hand dishwashing include as active detergent a mixture of dialkyl sulphosuccinates obtained from a mixture of C7 and C8 aliphatic alcohols, optionally with C6 alcohol. Improved performance and formulation benefits are obtained.
Patent ES-8506088-A1 (ES)
Title: Bacterial clone producing alpha-1-antitrypsin
IPC: C12R/
Filed: 1984-02-20
Abstract: Prodn. of a bacterial clone which produces human alpha-1-antitrypsin (AT) comprises first extracting and purifying total mRNA from human liver, then prepg. a fraction enriched in the mRNA for AT. This fraction is used for in vitro synthesis of double-strand cDNA and the DNA fraction enriched in material coding for AT. - Cohesive ends are attached to the DNA then this converted, in vitro, to hybrids with a plasmid vector having complementary ends. The hybrids are used to transform E.coli cells and the transformants contg. human DNA fragments selected. The selected clones contg. AT-DNA are isolated and those which can express AT are identified. Also claimed are double-stranded cDNA coding for AT and the E.coli clones contg. AT-DNA. - AT is useful for treatment of hereditary conditions which make the subject liable to pollutant-induced lung damage (esp. emphysema), partic. when caused by excessive release of proteolytic enzymes. Large amt. of AT can be made by cultivating the transformed bacteria.
Patent ES-8600246-A1 (ES)
Title: 4-Quinolone derivatives.
IPC: C07D409/04
Filed: 1984-02-24
Abstract: The present invention relates to 4-quinolone derivatives represented by the following general formula (I) and salts thereof, as well as their use as pharmaceuticals and methods for manufacturing them. < CHEM > In the formula, R<1> and R<2> are same or different and they are hydrogen, lower aklyl of one to eight carbon chain length or lower alkenyl of one to four carbon chain length R<3> stands for hydrogen, lower alkyl of one to eight carbon chain length, lower alkyl of one to eight carbon chain length with one or two hydroxyl group(s), lower alkyl or three to ten carbon chain length with one or two ether bond(s), or-(CH2)nA where n is an integer of 1 to 3 and A is acetyl, acetyloxy, cyano orphenoxy Z stands for phenyl with or without substituent(s) selected from a group consisting of hydrogen, halogen, lower alkyl of one to eight carbon chain length, lower haloalkyl of one to three carbon chain length, lower alkoxy of one to four carbon chain length and COOR<4> (in which R<4> is hydrogen or lower alkyl of one to four carbon chain length) or Z stands for unsaturated hetero ring radical with five or six members having nitrogen, oxygen or sulfur as hetero atom.
Patent ES-8506609-A1 (ES)
Title: Water-soluble combination of 1,5-dimethyl-2-phenyl-3-pyrazolone and sulphamide and process for its preparation
IPC: C07D231/26
Filed: 1984-05-04
Abstract: Water-soluble combination of 1,5-dimethyl-2-phenyl-3-pyrazolone (compound known under the name of, for example, "Phenazone") and sulphamide, consisting of a saline compound of general formula: < IMAGE > in which R is an alkali metal atom and R<1> and R<2> each represent a hydrogen atom or an aliphatic, aromatic or heterocyclic residue or a group of at least two of these residues. This combination makes it possible to simultaneously obtain the therapeutic effects of phenazine and of a sulphamide, while lending itself to the preparation of a stable aqueous solution containing the active principle in a form which is easily hydrolysable in the body.
Patent ES-8503239-A1 (ES)
Title: Process and apparatus for extracting fruit juices
IPC: A23N1/02
Filed: 1984-05-30
Abstract: Juice extractor apparatus which comprises a fruit- conveying support which carries loose fruit between separate elements in the form of a comb or rake. The conveying support drives the fruit against the cutting edge of a stationary blade which forms an integral part of a generally flattened tube, provided with a plurality of perforations, where, upon encountering the blade, the fruit is cut in a plane defined by the cutting edge of the blade, and the resulting parts of the cut fruit pass on opposite sides of the flattened tube. As the support conveys the cut fruit along the perforated flattened tube, the stationary comb-type elements located on each side of the tube and alternating with the comb-type support, it compresses each half of the fruit against the perforated tube and therefore the juice is expressed inside the flattened tube through the perforations.
Patent ES-8505213-A1 (ES)
Title: Unit for supplying and regulating a yarn for a textile machine, particularly a loom.
IPC: D03D47/34
Filed: 1984-07-23
Abstract: The yarn control unit (10) is arranged immediately after the yarn conveying roller (6). The yarn control unit (10) comprises at least one yarn guiding loop (12, 14) which is elastically supported and at least one fixed yarn guide (18). In a first position (I), the gap to the fixed yarn guide (18) is smaller than that of the second position (II), wherein the yarn guiding loop (12, 14) formed a yarn reserve (26). In the yarn control unit (10), the resistance due to the friction of the yarn (4) in the second position (II) of the yarn guiding loop (12, 14) is higher than the starting yarn tension. In the first position (I), the resistance due to the friction is smaller than the yarn tension required for transporting the yarn for the yarn conveying roller (6). The mounting of the unit is thereby particularly simple and the transport of the yarn is smooth and optimally adapted to the requirements of the textile machine.
Patent ES-8702948-A1 (ES)
Title: Streptokinase-coding recombinant vectors.
IPC: C12N9/70
Filed: 1984-10-09
Abstract: A recombinant vector adapted for transformation of a suitable host to produce streptokinase is disclosed, said recombinant vector comprising a vector into which a polydeoxyribonucleotide fragment which codes for the synthesis and secretion of strectokinase has been inserted. Nucleotide sequences encoding for secretion and synthesis of streptokinase are also disclosed, as well as a process for preparing the recombinant vector comprising: digesting a vector with a restriction endonuclease to produce linear vector DNA and ligating the linear vector DNA with a polydeoxyribonucleotide fragment which codes for synthesis and secretion of streptokinase, to produce a recombinant vector comprising a vector into which a polydeoxyribonucleotide fragment which codes for the synthesis and secretion of streptokinase has been inserted.
Patent ES-8507389-A1 (ES)
Title: Printing plate clamping mechanism for cylinder printing press
IPC: B41F13/10
Filed: 1984-12-18
Abstract: The clamping mechanism employs an open groove in the surface of the cylinder containing a fixing device for holding the opposite ends (PA,PB), the printing plate which are both fitted into the groove. The fixing device employs a single clamp rail (17) for both printing plate ends (PA,P'B), having a longer width in the radial direction of the cylinder (1) than in the peripheral direction ad pivoted about an axis parallel to the cylinder axis. - One side of the groove incorporates a biasing device (15,16) acting on the clamp rail (17) and a clamp piece (19) is fitted between the opposite side of the groove and the clamp rail. This defines two radial slits for securing the printing plate ends (PA,P'B) when the clamp rail is pivoted by the applied bias.
Patent ES-8608761-A1 (ES)
Title: Telephone set for public use having a integral management microprocessor.
IPC: H04M17/02
Filed: 1985-06-26
Abstract: The telephone set comprises a local logic unit having a microprocessor (30) operatively connected to: - a dialing keyboard (22) - a coin sorter (56) including an electronic selecting section - a coin receiving device (58-59) interposed between the sorter and a collecting channel (60) and activated directly by the microprocessor (30) - sensor means (62,64,76,78) responsive to the presence of at least one coin or token in the collecting channel and being adapted to send corresponding signals to the microprocessor - a cash or return device (68) located at the outlet of the channel (60) - a billing pulse detector (40) - a on-hook simulator member (SG) activated by the microprocessor - at least one main power supply (34) and - a reset member for the microprocessor, activated by the same at the end of the operations to ensure that the supply voltage drops below a set value.
Patent ES-8603849-A1 (ES)
Title: Process for producing aminothiazolylpropendicarboxylic acid monoesters.
IPC: C07D277/40
Filed: 1985-07-11
Abstract: Substd.-2-aminothiazole cpds. of the formulae (II), (III) and (IV) are new. Prepn. of a substd. 2-aminothiazole cpd. of the formula (VI) comprises treating a cpd. of the formula (I) with thiourea to give a cpd. of the formula (II), protecting the amino gp. of this to give a cpd. of the formula (III), treating this with a haloalkenoic acid ester to give a cpd. of the formula (IV), hydrolysing and decarboxylating this to give a cpd. of the formula (V) and treating this with an alcohol and a hemi-esterifying reagent. In the formulae Hal=halogen; each R independently=an ester-forming gp.; R1 and R2 each independently=H or an amino-protecting gp.; R3=H or COOR.
Patent ES-8701487-A1 (ES)
Title: Polymerisable composition.
IPC: A61K6/00
Filed: 1985-07-17
Abstract: A polymerizable composition is formed from (a) a polymerizable olefinically unsaturated substance, (b) a phosphorus oxyacid and an organic amine, at least one of which bears a polymerizable olefinically unsaturated group and optionally (c) a particulate inorganic material. Such compositions are useful in dental applications.
Patent ES-8607154-A1 (ES)
Title: Board power source, especially for a ship with variable speed diesel engine propulsion.
IPC: F02B3/06
Filed: 1985-10-02
Abstract: The invention relates to an on board power supply, particularily for a ship propelled by a variable speed diesel engine (1), comprising a first alternator (2) coupled to a diesel engine, an electronic regulator (4) for the first alternator, a rectifier (5) for rectifying the output current of the first alternator, a direct current motor (6) powered from the output of the rectifier, and a second alternator (8) coupled to the direct current motor. It also comprises means (13) for selectively feeding the regulator of the first alternator from the output (12) of the first alternator or from the output (11) of the second alternator.
Patent ES-8706104-A1 (ES)
Title: Process for the preparation of 2-alkyl-cyclopentanones.
IPC: C07C45/73
Filed: 1986-03-07
Abstract: 1. A process for the preparation of a cyclopentanone which is monoalkylated in the 2-position and of the formula I see diagramm : EP0194591,P6,F2 where R**1 is a branched or straight-chain aliphatic group of 2 to 12, preferably 4 to 8, carbon atoms and R**2 to R**7 may be identical or different and are each hydrogen or alkyl of 1 to 5 carbon atoms, preferably hydrogen or methyl, wherein a cyclopentanone of the formula II see diagramm : EP0194591,P6,F3 or a corresponding cyclopentanone, is reacted with an aldehyde of the formula III see diagramm : EP0194591,P6,F5 where R**1 has the above meanings, at from 80 to 280 degrees C, preferably from 100 to 200 degrees C, in the presence of hydrogen in an autoclave, over a catalyst which contains, as active components, on the one hand an oxide or a phosphate of magnesium, aluminium, titanium or zinc or of a rare earth metal, and on the other hand a noble metal of group VIII of the periodic table, preferably palladium.
Patent ES-8706727-A1 (ES)
Title: Treatment of sepiolite filler for rubber
IPC: C08K5/34
Filed: 1986-06-12
Abstract: The process, which improves the reinforcing power and dielectric character of the filler in vulcanisates of ethylenepropylene co-polymers, consists of (a) using sepiolite as the filler (b) drying it (c) suspending it with agitation at ambient temp. (d) adding 2.5-10 wt.% pyridine deriv. (e) agitating the suspension for less than 10 mins. (f) separating the solid prod. and (g) adding it as reinforcing filler to EP copolymer compsns. and vulcanising.
Patent IE-902447-A1 (IE)
Title: Tines structure in clinical applicator
IPC: A01K11/00
Filed: 1990-07-05
Abstract: A clinical applicator (10) for intradermal or subdermal administration of an active substance in a liquid vehicle, such as a vaccine or antigen, has a novel tines structure (26). The tines (26) are provided in the form of an array of eight individual tines (52), each comprising a body member of pyramid shape and having a channel (54) extending from the tip to the base of the body member and having walls at right angles to each other for the length of the channel and to the base. The individual tines (52) are arranged with their apices in a circle and are oriented in two groups of four tines in which the channel of each member forms one corner of a square.
Patent IE-902976-A1 (IE)
Title: Secondary containment system and method
Inventor: STISKIN HAL
IPC: F16L13/10
Filed: 1990-08-17
Abstract: A secondary containment pipe system disposed around a primary pipe system and comprising a joint that is divided along a central parting plane and has laterally projecting flanges that form internal passages for adhesive sealing cement, that is injected through ports while the joint is clamped together around secondary containment pipes. The joint has pipe sockets that have internal grooves that also are filled with injected cement, thus forming a continuous, uninterrupted seal around the interior of the joint, and also has spillover grooves and wells for minimizing leakage, and lateral aligning surfaces. The clamping means are C-shaped clips that can be left in place indefinitely. The secondary containment pipes also are divided, being formed by elongated pipe elements fitted together around the primary pipes and having snap-latching coupling means along their abutting edges. One embodiment has internal reinforcing flaps that extend across the abutting edges and define internal sealing passages along the coupling means to be filled with injected adhesive cement through external ports, and also has means along the free edges for holding the flaps in place. A second pipe embodiment has tongue-and-groove couplings along thickened edges, and internal passages along the couplings in the form of enlarged coupling grooves, and an external reinforcing strip is provided for optional use in pressurized systems.
Patent IE-904403-A1 (IE)
Title: Novel compounds
IPC: A61P31/04
Filed: 1990-12-06
Abstract: A compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein: R1 is a group -CH2-X where X is hydrogen, halogen, -CN, -N3, -OC(O)R5, S(O)nR5, -SH, -OC(O)NHR5, -NHCONHR5 or -NR6R7, where R5 is hydrogen optionally substituted C1-8 alkyl, or aryl, heteroaryl, aryl C1-4 alkyl or heteroaryl C1-4 alkyl in each of which the aromatic moiety is optionally substituted with the proviso that when X is -S(O)nR5, R5 does not represent hydrogen, R6 and R7 are independently hydrogen or C1-6 alkyl, or one of R6 and R7 is hydrogen and the other is -formyl, C2-8 alkanoyl, dialkoxyphosphoryl, aroyl, heteroaroyl, aryl C1-4 alkanoyl, heteroaryl C1-4 alkanoyl, C1-8 alkylsulphonyl, arylsulphonyl, heteroarylsulphonyl, aryl C1-4 alkylsulphonyl or heteroaryl C1-4 alkylsulphonyl, where any aromatic moiety in R6 or R7 is optionally substituted, and n is 0, 1 or 2; R2 is hydroxy or optionally substituted C1-8 alkoxy; R3 is an amino group or a derivative thereof; and each R4 is hydrogen.
Patent IE-920339-A1 (IE)
Title: Amino Acid Derivatives
Inventor: BROADHURST MICHAEL JOHN
IPC: C07C/
Filed: 1992-01-31
Abstract: The invention provides compounds of the formula wherein A represents the group R<1> represents hydrogen, amino, protected amino, acylamino or lower alkyl optionally substituted by aryl, hydroxy, protected hydroxy, amino, protected amino, acylamino, maleimido, succinimido, naphthalimido, 2,3-dihydro-1,3-dioxo-1H-benz[d,e]isoquinol-2-yl, carboxy, protected carboxy, carbamoyl, mono(lower alkyl)carbamoyl, di(lower alkyl)carbamoyl, di(lower alkyl)amino, carboxy-lower alkanoylamino, pyrrolidino or morpholino; R<2> represents hydrogen or lower alkyl optionally substituted by aryl, amino, protected amino, di(lower alkyl)- amino, guanidino, carboxyl, protected carboxyl, carbamoyl, mono(lower alkyl) carbamoyl, di(lower alkyl)carbamoyl, di(lower alkoxy)phosphinyl, dihydroxyphosphinyl, pyrrolidino, piperidino or morpholino; R<3> represents hydrogen or lower alkyl optionally substituted by hydroxy, protected hydroxy, amino or protected amino; R<4> represents hydrogen, hydroxy, lower alkoxy or benzyloxy; and R<5> represents hydrogen or halogen and their pharmaceutically acceptable salts. These compounds are useful for the control or prevention of degenerative joint diseases or for the treatment of invasive tumours, atherosclerosis or multiple sclerosis. They can be manufactured according to known methods.
Patent SU-1841127-A1 (SU)
Title: Method of producing bistrinitroethyl-ethylenedinitramine (substance "n") via neutralised methylol ethylene diamine derivative
Inventor: ZHuzgov Stanislav Nikolaevich
IPC: C07C211/15
Filed: 1966-04-06
Granted: 2016-04-27
Abstract: FIELD: chemistry.SUBSTANCE: invention relates to improved method of producing bistrinitroethyl-ethylenedinitramine (substance “N”), used as explosive. Method is realised by reacting of methylol derivative of ethylenediamine neutralised with acid with nitroform followed by treatment of obtained product with sulphuric-nitric acid mixture, wherein in order to increase target product yield and increasing safety of process, as neutralising acid 70-80 % sulphuric acid is taken.EFFECT: improved method of producing bistrinitroethyl-ethylenedinitramine; method also enables to eliminate necessity of frequent disconnection of paste-forming device to remove crust, breaking heat exchange in apparatus, and reduce consumption of acid per unit of finished product.1 cl, 2 ex
Patent AT-514035-A1 (AT)
Title: Verfahren zur Herstellung eines flächenartigen Elements mit von einer ebenen Oberfläche abweichender Oberfläche, Formteil zur Herstellung eines derartigen flächenartigen Elements sowie flächenartiges Element
IPC: B28B7/02
Filed: 2013-03-13
Abstract: Bei einem Verfahren zur Herstellung eines flächenartigen Elements mit von einer ebenen Oberfläche abweichender Oberfläche aus aushärtendem Material sind folgende Schritte vorgesehen:Bereitstellen eines ersten Formteils, welches eine zu einer Oberfläche des herzustellenden Elements (24) entsprechende Formgebung aufweist,- Bereitstellen eines zweiten Formteils (16), welches eine zu einer weiteren Oberfläche des herzustellenden Elements (24) entsprechende Formgebung aufweist,-Verbinden des ersten und zweiten Formteils (5, 16), wobei zwischen den Oberflächen (7, 19) der Formteile (5, 16) entspre­ chend dem herzustellenden Element (24) ein Abstand und/oder ein Hohlraum bzw. eine Vertiefung in wenigstens einer der Oberflächen (7, 19) der Formteile (5, 16) entsprechend dem herzustellenden Element vorgesehen wird,Einbringen des aushärtenden Materials in den durch dieFormteile (5, 16) begrenzten Hohlraum,- Aushärten des aushärtenden Materials in den miteinander verbundenen Formteilen (5, 16), undÖffnen der Formteile (5, 16) und Entnehmen des ausge­härteten flächenartigen Elements (24).Weiters werden ein Formteil (5, 16) zur Herstellung eines derartigen flächenartigen Elements und ein flächenartiges Element zur Verfügung gestellt.
Patent WO-9717547-A1 (WO)
Inventor: MARK RUDOLF
IPC: F16B13/12
Filed: 1996-10-23
Abstract: The invention relates to a securing component (1) with an internally threaded (20) cylindrical jacket (2) having at least one support (4) at one face projecting beyond the jacket (2) in a plane perpendicular to a central longitudinal axis (3) and there are at least two radially deformable spreaders (29) projecting beyond the jacket (2) at its end region (23) away from the support (4) and the jacket (2) with the spreaders (29) consists of a one-piece metal component, in which at least one anchoring projection (7) is arranged on the support (4), the spreaders (29) converge in a longitudinal direction and faces (28) of the spreaders (29) away from the support (4) are arranged at an angle to each other.
Patent WO-0116048-A1 (WO)
Inventor: GOODWIN PETER COLE
IPC: C04B24/38
Filed: 2000-08-24
Abstract: A method and agent for treating a cementitious material for extrusion, comprising adding to the cementitious material a viscosity enhancing agent and a dispersion agent in a quantity sufficient to increase the efficacy of the viscosity enhancing agent. By increasing the efficacy of the viscosity enhancing agent, extrudability may be maintained with less viscosity enhancing agent or a lower grade (cheaper) viscosity enhancing agent than is conventionally used, or the extrudability may be improved for the same quantity of viscosity enhancing agent compared to a conventional dosage.