baber/WOPTO huggingface dataset:
Patent CA-3137971-A1 (CA)
Inventor: TAGAYA YUTAKA
IPC: A61K38/16
Filed: 2020-04-30
Abstract: Les cytokines de la famille yc, l'interleukine-2 (IL-2), l'interleukine-4 (IL-4), l'interleukine-7 (IL-7), l'interleukine-9 (IL-9), l'interleukine-15 (IL-15) et l'interleukine-21 (IL-21), sont associées à des maladies humaines importantes, telles que l'alopécie et les troubles associés à l'alopécie. L'invention concerne des compositions, des méthodes et des kits pour moduler la signalisation par au moins un élément de la famille des cytokines yc pour inhiber, améliorer, réduire la gravité de, traiter, retarder l'apparition de ou prévenir au moins un trouble associé à l'alopécie.
Patent CA-3139345-A1 (CA)
Inventor: SCHLUTER WERNER
IPC: F21S4/26
Filed: 2021-11-17
Abstract: A watertight LED arrangement (1) is provided that extends in a longitudinal direction (L). A strip-shaped LED board (3) is provided with a multiplicity of LEDs (2) on its upper side and at least one cable (4) is electrically connected to the LED  board (3).  A one-piece, elastically formed watertight sheath (6) surrounds the LED board (3) and defines a light emission wall (5) at least on its upper side opposite the LEDs (2), the sheath (6) receiving the LED board (3) in a form-fitting manner. A cavity (7) extends in the longitudinal direction (L) between the upper side of the LED board (3) and the light emission wall (5). At least a portion of a sealing element (10a) extends from the LED  board (3) toward the light emission wall (5) and defines an edge of the cavity (7).
Patent CA-3139818-A1 (CA)
Title: Airborne topo-bathy lidar system and methods thereof
Inventor: HOPPER NATHAN LEE
IPC: G01S17/89
Filed: 2020-05-30
Abstract: Airborne LiDAR bathymetry systems and methods of use are provided. The airborne LiDAR bathymetry system can collect topographic data and bathymetric data at high altitudes. The airborne LiDAR bathymetry system has a receiver system, a detector system, and a laser transmission system.
Patent CA-3141518-A1 (CA)
Inventor: HOBAICA DAVID E
IPC: E04H4/04
Filed: 2021-12-03
Abstract: A modular swimming pool includes a precast base unit and a precast riser unit that can be assembled at an installation site to define an interior volume in which a human can swim. The precast riser unit is secured to the base unit. The upper surface of the precast base unit and at least one internal surface of the precast riser unit define the interior volume of the modular pool when the precast base unit and the precast riser unit are secured together. A  modular swimming pool assembly is also provided. A method of assembling a modular swimming pool is also provided.
Patent CA-3144153-A1 (CA)
Title: Dry eye mitigation for ocular aberrometry systems and methods
Inventor: HALL MAX
IPC: A61B3/10
Filed: 2020-09-25
Abstract: Techniques are disclosed for systems and methods to provide dry eye and/or tear film hydration monitoring in the context of ocular aberrometry. An ocular aberrometry system (100) includes a wavefront sensor (120) configured to provide wavefront sensor data associated with an optical target (102) monitored by the ocular aberrometry system (100) and a logic device (140) configured to communicate with the wavefront sensor (120). The logic device (140) is configured to receive (1102) ocular aberrometry output data including at least the wavefront sensor data provided by the wavefront sensor (120), determine (1106) a tear film hydration state associated with the optical target based, at least in part, on the received ocular aberrometry output data, and generate (1110) user feedback corresponding to the determined tear film hydration state based, at least in part, on the received aberrometry output data and/ or the determined tear film hydration state.
Patent CA-3154876-A1 (CA)
Title: Compositions and methods for in vitro activation and expansion of serial killer t cell populations and passive immunization of a cancer patient with tumor cell killing cells
Inventor: BORRIELLO FRANK
IPC: C12N5/0783
Filed: 2020-10-21
Abstract: The described invention provides a method for in vitro immunoactivation of mononuclear cells by contact with one or more populations of engineered leukocyte stimulator cells genetically engineered to express a core of 3 essential immunomodulator peptides, and optionally additional R immunomodulator peptides, and use of a cell product comprising the expanded and activated mononuclear cell population comprising one or more subpopulations of cytotoxic serial killer cells for passive immunization of a cancer patient not currently under the influence of an immunosuppressive regimen.
Patent CA-3155946-A1 (CA)
Title: Systemes permettant de faire fonctionner des dispositifs microfluidiques
Inventor: ANGELES ANGEL NAVAS
IPC: B81B7/02
Filed: 2020-10-23
Abstract: L'invention concerne des systèmes pour faire fonctionner un dispositif microfluidique. Les systèmes comprennent une première surface conçue pour s'interfacer et s'accoupler fonctionnellement à un dispositif microfluidique et un couvercle conçu pour retenir le dispositif microfluidique sur la première surface. Le couvercle comprend une première partie ayant un premier orifice de fluide conçue pour s'accoupler fonctionnellement avec et faire s'écouler un milieu fluidique dans et/ou le faire sortir d'une première entrée/sortie de fluide du dispositif microfluidique et une seconde partie ayant un second orifice de fluide conçue pour s'accoupler fonctionnellement avec et faire s'écouler un milieu fluidique dans et/ou le faire sortir d'une seconde entrée/sortie de fluide du dispositif microfluidique. La seconde partie du couvercle peut être séparée de la première partie et est mobile entre une position fermée et une position ouverte.
Patent CA-3156219-A1 (CA)
Inventor: BRETON REMI
IPC: B60W10/18
Filed: 2022-04-22
Abstract: A method for controlling engine braking in a vehicle comprises: determining a position of a throttle operator; determining a speed of the vehicle; and determining an engine braking mode selected. In response to the position of the throttle operator being a fully released position and the selected braking mode being a first engine braking mode: controlling an engine and a position of a throttle valve according to the first engine braking mode for applying a first level of engine braking. In response to the position of the throttle operator being the fully released position and the selected braking mode being the second engine braking mode: controlling the engine and the position of the throttle valve according to the second engine braking mode based at least on the speed of the vehicle for applying a second level of engine braking. A  vehicle implementing the method is also disclosed.
Patent CA-3157859-A1 (CA)
Inventor: HUANG ERIC YI-CHUN
IPC: A61K47/24
Filed: 2020-10-15
Abstract: L'invention concerne des compositions de nanoparticules lipidiques (LNP) comprenant des polypeptides de modulation immunitaire et leurs utilisations. Les compositions de LNP de la présente invention comprennent des agents thérapeutiques à ARNm codant des polypeptides de modulation immunitaire, par exemple, l'interleukine 2 (IL-2) et/ou le facteur de stimulation des colonies de granulocytes macrophages (GM-CSF). Les compositions de LNP de la présente invention peuvent stimuler des lymphocytes T régulateurs, par exemple, augmenter le niveau et/ou l'activité des lymphocytes T régulateurs in vivo ou ex vivo.
Patent CA-3160221-A1 (CA)
Inventor: TANTHANA JAK
IPC: B01D53/14
Filed: 2020-12-09
Abstract: A non-aqueous solvent system configured to remove acidic gas from a gas stream comprises a solution formed of a chemical absorption component and a physical absorption component. The chemical absorption component includes a nitrogenous base, wherein the nitrogenous base has a structure such that it reacts with a portion of the acidic gas. The physical absorption component includes an organic diluent that is non-reactive with the acidic gas and that has a structure such that it absorbs a portion of the acidic gas at a pressure above atmospheric pressure. The solvent system has a solubility with water of less than about 10 g of solvent per 100 mL of water.
Patent CA-3160930-A1 (CA)
Title: Fuel dispenser having selectively viewable secondary display
Inventor: SLABBEKOORN SCOTT D
IPC: G06Q50/06
Filed: 2020-12-04
Abstract: A fuel dispenser comprises a housing enclosing fluid handling components including a fluid flow meter. The housing has a user interface including a panel display. A control system is in electrical communication with the user interface and is operative to display money and volume information on the panel display during a fueling transaction. A secondary display having digit structure that registers fuel dispensing information is in electrical communication with the control system. The secondary display is configured to not be viewable by a customer during a fueling transaction.
Patent CA-3161174-A1 (CA)
Inventor: BOEHME ALEXANDER
IPC: C12Q1/6886
Filed: 2020-12-10
Abstract: The present invention relates to the use of Interleukin-4?induced gene 1 (IL4I1) as well as metabolites as produced by IL4I1 as marker in diagnosis and therapy of cancer and related metastasis and/or resistance to immunotherapy.
Patent CA-3164844-A1 (CA)
Inventor: KATTIMANI MURALIDHAR
IPC: G06F9/451
Filed: 2022-06-22
Abstract: Certain aspects of the present disclosure provide techniques for configuring a software application through a remote configuration service. An example method generally includes receiving, from a remote configuration service, a declarative construct. Generally, the declarative construct includes a definition of a workflow in an application to be executed within a player application deployed on a client device. Information associated with the definition of the workflow is extracted by parsing the declarative construct according to a schema defining a format of the declarative construct. The workflow is executed in the player application based on the extracted information defining functionality of the workflow.
Patent CA-3170301-A1 (CA)
Title: Method and system for sizing a chip in engine fluid
Inventor: AL-KHAIRY ISSAM
IPC: F01M11/10
Filed: 2022-08-10
Abstract: Methods and systems of estimating a size of a chip in engine fluid of an engine are provided. One method comprises detecting the chip at a magnetic chip detector immersed in the engine fluid, burning the chip by Joule heating using a single delivery of electric current through the chip via the first and second terminals of the magnetic chip detector, determining an amount of energy consumed to burn the chip, and estimating the size of the chip based on the amount of energy consumed to burn the chip.
Patent CA-3170474-A1 (CA)
Inventor: SHAFIEI MEHDI
IPC: H01G9/012
Filed: 2021-02-05
Abstract: Disclosed is a metal foil capacitor, preferably an aluminum capacitor, comprising a modified metal foil comprising a base metal, preferably an aluminum foil. The modified metal foil capacitor may satisfy at least two of the following conditions: (a) the modified metal foil has a surface area of at least 10 times greater than an unmodified metal foil; (b) the modified metal foil has a dielectric constant (k) of at least 5; (c) the modified metal foil has a thickness of at least 1 micron; and/or (d) the modified metal foil comprises at least one metal in addition to the base metal, wherein the at least one metal is present in an amount of at least 0.01 wt.% based on the total weight of the modified metal foil. Methods for preparing the metal foil capacitor are also disclosed.
Patent CA-3173717-A1 (CA)
Title: Reinforced tie rod and a building wall using the same
Inventor: ESPINOSA THOMAS M
IPC: E04G17/065
Filed: 2021-04-02
Abstract: A building wall includes a bottom plate and a top plate; a first stud and a second stud extending between the bottom plate and the top plate, the first stud and the second stud are spaced apart and next to each other; a tie rod including a first end portion operably anchored to a foundation and a second end operably attached to the building wall; a sheathing attached to the bottom plate, the top plate, the first stud and the second stud; a longitudinal member including a longitudinal hole, the tie rod extending through the hole; and the longitudinal member is operably attached to the sheathing.
Patent CA-3173870-A1 (CA)
Title: Plant sourced protein-polyphenol complexes
Inventor: BRODDY WILLIAM LESLIE
IPC: A23L33/105
Filed: 2021-10-20
Abstract: Compositions and methods are provided, wherein one or more plant protein(s) are combined with one or more fruit, vegetable, nut or grain sources of phenolics to generate protein-phenol complexes within the mixture. The source of phenolics primarily derive from plant waste, residuals, by-products or side streams, such as, for example, the solids which remain after the extraction of juice from fruit or oil pressed from olives, nuts or grains (e.g., pomace), or fruit and vegetables, etc., which could not be sold for some reason or another. In one embodiment, this mixture constitutes an Admixture that can be added to meat analogue formulations. In one embodiment, this mixture constitutes a Base Substance to generate a Meat Analogue and/or Final Product, which can provide a replacement for different types of meat including beef, buffalo, deer, chicken, turkey, pork, fish, shellfish, etc.
Patent CA-3173988-A1 (CA)
Title: Pyrazol-3-ones that activate pro-apoptotic bax
Inventor: WALENSKY LOREN D
IPC: A61P35/02
Filed: 2012-10-11
Abstract: This application relates to pyrazol-3-one compounds including compounds of Formula l that activate pro-apoptotic BAX. Also featured are methods of using such compounds, e.g., for the treatment or prevention of diseases, disorders, and conditions associated with deregulated apoptosis of cells (e.g., insufficient apoptosis of diseased or damaged cells or essentially the absence of apoptosis of diseased or damaged cells). (see formula I)
Patent CA-3176954-A1 (CA)
Inventor: PAPASOTIRIOU IOANNIS
IPC: C07K16/10
Filed: 2021-05-18
Abstract: La présente invention concerne : une nouvelle méthode pour la production d'anticorps monoclonaux véritablement entièrement humains contre le SARS-CoV-2 à l'aide de cellules sanguines humaines isolées. Ces antigènes peuvent comprendre, sans s'y limiter, des séquences peptidiques trouvées dans des protéines d'enveloppe ou de spicule de protéines du SARS-CoV-2.
Patent CA-3177261-A1 (CA)
Inventor: WAN HUIXIN
IPC: C07D277/62
Filed: 2020-11-10
Abstract: A benzothiazolyl biaryl compound represented by general formula I, or a pharmaceutically acceptable salt thereof, or an enantiomer, a diastereoisomer, a tautomer, a torsional isomer, a solvate, a polymorph, or a prodrug thereof, a preparation method therefor, and a use thereof as a KRASG12C inhibitor.
Patent CA-3178252-A1 (CA)
Title: Red cell extracellular vesicles (rcevs) containing cargoes and methods of use and production thereof
Inventor: CHARTON KARINE
IPC: A61K38/00
Filed: 2021-05-11
Abstract: The application relates to the use of loaded red blood cells (e.g. "RBCs", "red cells" or "erythrocytes") or red blood cell precursors to produce red cell extracellular vesicles (RCEVs) containing cargos, including cargos comprising biologically active ingredients. Notable red cell precursors include hematopoietic stem cells (HSCs), induced pluripotent stem cells (iPSCs), and reticulocytes. The cargo may comprise nucleic acids, proteins, small molecules, or components of a gene editing system, including CRISPR/Cas9. The RCEVs may be used to treat of diseases and disorders including autoimmune disorders, cancers, cardiovascular diseases, gastrointestinal diseases, genetic disorders, or inflammatory diseases. The RCEVs may also be used to carry antigens and or immune modulator, for use in eliciting immune or immune tolerance responses. Also provided are methods for producing cargo loaded RCEVs (CLRCEVs) by first loading cargo into red cells and then by vesiculating the cargo loaded red cells to yield the CLRCEVs.
Patent CA-3180407-A1 (CA)
Title: Charging pole
Inventor: SOHL ALEXANDER
IPC: B60L53/68
Filed: 2021-06-01
Abstract: The invention relates to a method for generating and delivering charging current for an electric vehicle in a charging column, comprising the method steps of registering a first initial process, evaluating the first initial process, and starting the charging process in accordance with the result of the evaluation, the first initial process being different from a start command from a user for starting a charging process. The invention also relates to a charging column used for carrying out the method.
Patent CA-3181966-A1 (CA)
Inventor: BOWERS W TAISTO
IPC: G06F3/00
Filed: 2022-02-17
Abstract: Un mode de réalisation d'un procédé de positionnement de caractéristiques dans un espace de conception numérique consiste à recevoir une demande d'un utilisateur pour placer un premier élément dans l'espace de conception, et, sur la base de la demande, à placer la première caractéristique dans l'espace de conception, et à coupler une première poignée de positionnement à la première caractéristique dans l'espace de conception. La première poignée de positionnement est représentée graphiquement dans l'espace de conception et manipulable par l'utilisateur, la première poignée de positionnement a une position fixe et une orientation fixe par rapport à la première caractéristique, et la première poignée de positionnement comprend une première surface de face et définit un premier vecteur. Le procédé consiste également à déplacer la première caractéristique dans une position et une orientation prédéterminées par rapport à une caractéristique cible dans l'espace de conception par accouplement de la première poignée de positionnement à une poignée de positionnement cible couplée à la caractéristique cible.
Patent CA-3183333-A1 (CA)
Title: Apparatus for forming a cone for housing a needle in a syringe, method for making a cone for housing a needle in a syringe, and the syringe thereof
Inventor: CHILLON ALBERTO
IPC: C03B40/027
Filed: 2021-06-21
Abstract: An apparatus for forming (4) a housing cone (8) of a needle in a syringe body (12) of a glass syringe, comprising a forming tool (16) shaped to make a hole (20) for the creation of the housing cone (8), a lubricant-coolant liquid dispensing device (24), wherein the forming tool (16) comprises a grip portion (28), a tip (32), a tip body (36), interposed between the tip (32) and the grip portion (28), suitable for making said hole (20). The grip portion (28), tip body (36), and tip (32) are in one piece and aligned along a prevailing extension axis (X-X). The tip body (36), with respect to a cross-sectional plane perpendicular to the prevailing extension axis (X-X), has a non- circular cross section, inscribed within the maximum circle (40) having as its radius the maximum distance between a point (P) of the cross section and the prevailing extension axis (X-X), measured on the cross-sectional plane.
Patent CA-3184119-A1 (CA)
Title: Composition durcissable et corps durci forme a partir de celle-ci
Inventor: KAWASAKI TAKAYOSHI
IPC: C08F220/30
Filed: 2021-07-13
Abstract: La présente invention concerne : une composition durcissable qui contient un composé de bismuth, dans lequel un ester d'acide phosphorique ayant groupe (méth)acryloyle est lié au bismuth, et un composé nitrile ayant une double liaison carbone-carbone polymérisable par voie radicalaire ; un corps durci qui est obtenu par durcissement de cette composition durcissable ; un corps multicouche qui est composé du corps durci décrit ci-dessus et un corps durci qui est obtenu par durcissement d'une composition durcissable photochromique ; et un matériau de protection contre les rayonnements qui est formé du corps durci décrit ci-dessus ou du corps multicouche décrit ci-dessus.
Patent CA-3187130-A1 (CA)
Inventor: JASPERSE JEFFREY R
IPC: G01J3/427
Filed: 2021-07-23
Abstract: Sont divulgués des procédés et des systèmes de spectroscopie d'absorbance comprenant un analyseur de spectroscopie comprenant : un dispositif d'élément optique positionné pour recevoir une lumière d'analyse qui passe à travers un échantillon d'un échantillon de fluide en provenance d'une unité d'éclairage, la lumière d'analyse comprenant une première lumière dans une première plage de lumière et une seconde lumière dans une seconde plage de lumière différente de la première plage de lumière, le dispositif d'élément optique comprenant : un ensemble boîtier définissant un espace interne ; et un miroir-réflecteur dichroïque à l'intérieur de l'espace interne positionné pour recevoir la lumière d'analyse, le réflecteur-miroir dichroïque étant configuré pour filtrer la lumière d'analyse de telle sorte qu'une première partie de la lumière d'analyse dans la première plage de lumière soit réfléchie par le réflecteur-miroir dichroïque en tant que lumière de spectromètre, et de telle sorte qu'une seconde partie de la lumière d'analyse dans la seconde plage de lumière passe à travers le réflecteur-miroir dichroïque en tant que lumière de détecteur.
Patent CA-3188271-A1 (CA)
Inventor: COLPAERT JEROEN RENE MARIA
IPC: A22C17/14
Filed: 2021-08-31
Abstract: The invention provides a system (1) for sizing a natural intestine (100), wherein the system (1) comprises (i) a product carrier (10), (ii) a product transport and sealing system (20), (iii) a measuring system (30), and (iv) a control system (90); wherein the product carrier (10) comprises a fluid channel (19) and a measuring portion (15), wherein a product carrier surface (11) at the measuring portion (15) comprises one or more perforations (12) fluidly connected to the fluid channel (19); wherein the product transport and sealing system (20) is configured (i) for moving the intestine (100) over the product carrier (10), wherein the intestine (100) surrounds the product carrier surface (11), and (ii) for temporarily sealing the intestine (100) along at least part of the measuring portion (15); wherein the measuring system (30) comprises a radiation sensor system (32) for measuring a cross-sectional dimension (102) of the intestine (100) at the measuring portion (15) ), a pressure sensor (36) for sensing a fluid pressure (206) of the fluid (200) in the fluid channel (19), and a flow sensor (37) for sensing a fluid flow (209) of the fluid (200) in the fluid channel (19); and wherein the control system (90) is configured for determining a cross-sectional size of the intestine (100) at the measuring portion (15) based on a combination of signal of the radiation sensor system (32), a signal of the pressure sensor (36), and a signal of the flow sensor (37).
Patent CA-3190536-A1 (CA)
Title: Control system for a refuse vehicle
Inventor: KOGA JEFFREY
IPC: B65F3/02
Filed: 2023-02-21
Abstract: A refuse vehicle includes a chassis, an energy storage device, a body, a first electric power take-off system, and a second electric power take-off system. The energy storage device is supported by the chassis and is configured to provide electrical power to a prime mover. Activation of the prime mover selectively drives the refuse vehicle. The body is supported by the chassis. The first electric power take-off system is coupled to at least one of the body and the chassis, and includes a first motor that is configured to drive a first hydraulic pump to convert electrical power received from the energy storage device into hydraulic power. The second electric power take-off system is coupled to at least one of the body and the chassis, and includes a second motor that is configured to drive a second hydraulic pump to convert electrical power received from the energy storage device into hydraulic power.
Patent CA-3192710-A1 (CA)
Title: Methods of treating neuronal diseases using aimp2-dx2 and optionally a target sequence for mir-142 and compositions thereof
Inventor: CHOI JIN WOO
IPC: A61P25/28
Filed: 2021-09-30
Abstract: Disclosed herein are methods of treating neuronal diseases, comprising administering to a subject in need thereof a vector comprising AIMP2-DX2 and optionally a target sequence for miR-142.