baber/WOPTO huggingface dataset:
Patent FI-914477-A0 (FI)
Inventor: KIENER ANDREAS
IPC: C07D241/02
Filed: 1991-09-24
Abstract: Microorganisms which are capable of growing with 2,5-dimethylpyrazine as the sole carbon, nitrogen and energy source. These microorganisms hydroxylate heterocycles of general formula:  (* CHEMICAL STRUCTURE *) I or  (* CHEMICAL STRUCTURE *) II to heterocycles of general formula:  (* CHEMICAL STRUCTURE *) III or  (* CHEMICAL STRUCTURE *) IV The latter compounds are accumulated in the growth medium.
Patent FI-922640-A0 (FI)
Inventor: AUSTEVOLL OEYSTEIN
IPC: B01D35/02
Filed: 1992-06-08
Abstract: PCT No. PCT/NO90/00182 Sec. 371 Date Jul. 28, 1992 Sec. 102(e) Date Jul. 28, 1992 PCT Filed Dec. 5, 1990 PCT Pub. No. WO91/08819 PCT Pub. Date Jun. 27, 1991.The filter arrangement is provided with a filter in the form of an endless conveyor which is releasably mounted within a transport chute through which a flow of water can be directed. The filter is formed as a unit to be released from supports at the bottom of the transport chute for ease of cleaning. The filter is further pivotally mounted at the lower end so as to be adjusted angularly relative to the flow of water through the transport chute. Seals are provided between the sides of the filter and the side walls of the transport chute to preclude passage of liquid. A plurality of such filters may be disposed within the transport chute and may be associated with various discharge conveyors for discharging materials which have been filtered out of the flow of liquid.
Patent FI-930831-A0 (FI)
Inventor: CAPRARO HANS GEORG
IPC: C08G65/32
Filed: 1993-02-24
Abstract: Naphthalocyanine chelate complexes of the formula I, <IMAGE> which contain aluminium, gallium, indium, tin, ruthenium or, preferably, germanium as the central atom M, and wherein the other symbols are as defined in Claim 1. The complexes may be used, inter alia, for the photodynamic chemotherapy of tumours.
Patent FI-944454-A0 (FI)
Inventor: EBY ERIC
IPC: G02B5/08
Filed: 1994-09-26
Abstract: The present invention provides a coating for a transparent substrate which exhibits a "neutral" color through a wide range of angles of incidence of light. The coating employs a base coat adjacent the transparent substrate having a thickness of no more than about 275 Å and may include two reflective metal layers having an intermediate layer of an anti-reflective metal oxide therebetween and an outer anti-reflective layer of metal oxide over the second reflective metal layer. If so desired, the coating of the invention may include an abrasive-resistant overcoat as its outermost layer. This overcoat is desirably formed of an abrasive-resistant metal oxide, such as zinc oxide applied at a thickness which does not significantly affect the optical properties of said coated substrate.
Patent FI-950461-A0 (FI)
Inventor: EISEN NORBERT
IPC: C08G18/48
Filed: 1995-02-02
Abstract: The use of cpds. (A) having at least two reactive (w.r.t. isocyanates) hydrogen atoms, a mol.wt. of 150-1500 and contg. a tert. nitrogen atom, for increasing the solubility of hydrofluoroalkanes and/or pure hydrocarbons in the polyol component, for the prepn. of hard polyurethane foams obtd. by reacting polyisocyanates in the presence of hydrofluoroalkane and/or pure hydrocarbon foaming agent (B) and opt. other known auxiliary agents and additives, is claimed. Pref. (A) is a polyether having a mol.wt. of 250-500 and is pref. obtd. by reacting ethylene diamine or triethanolamine with propylene- and/or ethylene oxide. (B) is pref. 1,1,1,4,4,4-hexafluorobutane, cyclopentane, n-pentane and/or isopentane, 2,2-dimethylbutane or a mixt. of n-pentane, isopentane and/or cyclopentane and/or cyclohexane.
Patent FI-955439-A0 (FI)
Inventor: SAMUELS GLENN JAY
IPC: A61K31/535
Filed: 1995-11-10
Abstract: Mycophenolate mofetil and mycophenolic acid can be conveniently manufactured into high dose oral formulations by the hot melt filling of a supercooled mycophenolate mofetil or mycophenolic acid liquid into a pharmaceutical dosage form. High dose oral pharmaceutical formulations and manufacturing methods therefor are disclosed.
Patent IL-59007-A0 (IL)
Title: Recombinant dna molecules and their method of production
Inventor: MURRAY KENNETH
IPC: C12Q1/00
Filed: 1979-12-20
Abstract: Recombinant DNA molecules and hosts transformed with them which produce polypeptides displaying HBV antigenicity and genes coding therefor and methods of making and using these molecules, hosts, genes and polypeptides. The recombinant DNA molecules of this invention are characterized by structural genes that code for at least one polypeptide displaying HBV antigenicity. In appropriate hosts these recombinant DNA molecules permit the production and identification of genes and polypeptides characteristic of HBV antigenicity and their use in compositions and methods for detecting HBV virus infections in humans and stimulating the production of antibodies against this infection.
Patent IL-79303-A0 (IL)
Title: Mixed metal layered hydroxideclay adducts as thickeners for water and other hydrophilic fluids
IPC: C01B33/44
Filed: 1986-07-01
Abstract: Novel compositions useful as fluid gelling agents, especially for use in subterranean applications such as drilling fluids, are prepared by reacting an aqueous dispersion of a clay, such as bentonite, with an aqueous gel of a monodispersed mixed metal layered hydroxide.
Patent IL-91460-A0 (IL)
Title: Cycloalkyl-substituted glutaramide antihypertensive agents
IPC: A61K31/341
Filed: 1989-08-29
Abstract: Compounds of the formula: <CHEM> Wherein A completes a 5 or 6 membered carbocyclic ring which may be saturated or monounsaturated; R<1> is H or (C1-C4)alkyl; R and R<4> are H, (C1-C6)alkyl, C3-C7 cycloalkyl, benzyl, or an alternative biolabile ester-forming group; Y is either a direct bond or an alkylene group of from 1 to 6 carbon atoms; R<2> is H, aryl, heterocyclyl, R<6>CONR<5>-, R<7>NR<5>CO-, R<7>NR<5>SO2- or R<8>SO2NR<5>-, with the proviso that Y is not a direct bond when R<2> is H, aryl or heterocyclyl; wherein R<5> is H, (C1-C6)alkyl or aryl(C1-C6)alkyl; R<6> is (C1-C6)alkyl, aryl, aryl(C1-C6)alkyl, heterocyclyl, heterocyclyl(C1-C6)alkyl or a group of the formula R<9>R<1><0>R<1><1>C- wherein R<9> is H, OH, (C1-C6)alkoxy, (C1-C6)alkyl, hydroxy(C1-C6)alkyl, aryl(C1-C6)alkyl, (C2-C6)alkenyl, heterocyclyl, heterocyclyl(C1-C6)alkyl, R<1><2>CONH-, R<1><2>SO2NH- or (R<1><3>)2N-; R<1><0> and R<1><1> are H or (C1-C6)alkyl; or R<1><0> is H and R<1><1> is amino(C1-C6)alkyl, imidazolylmethyl, aryl, aryl(C1-C6)alkyl, aryl(C1-C6)alkoxy(C1-C6)alkoxy, hydroxy(C1-C6)alkyl or methylthio(C1-C6)alkyl; or the two groups R<1><0> and R<1><1> form a 3 to 6 membered carbocyclic ring or a pyrrolidine or piperidine ring which may optionally be substituted by amino, (C2-C4)alkanoyl or aroyl; R<1><2> is (C1-C6)alkyl, (C3-C7)cycloalkyl, aryl, aryl(C1-C6)alkyl, heterocyclyl or heterocyclyl(C1-C6)alkyl; each R<1><3> is H, (C1-C6)alkyl, aryl(C1-C6)alkyl or the two groups R<1><3> form a pyrrolidinyl, piperidino, morpholino, piperazinyl or N-(C1-C4)alkyl-piperazinyl group; R<7> is (C1-C6)alkyl, aryl, aryl(C1-C6)alkyl, heterocyclyl, heterocyclyl(C1-C6)alkyl or a group of the formula R<1><0>R<1><1>R<1><4>C- wherein R<1><0> and R<1><1> are as previously defined and R<1><4> is (R<1><3>)2NCO-, R<1><2>OCH2- or R<1><5>OCO, wherein R<1><2> and R<1><3> are as previously defined and R<1><5> is (C1-C6)alkyl, (C3-C7)cycloalkyl or aryl(C1-C6)alkyl; and R<8> is (C1-C6)alkyl, aryl, aryl(C1-C6)alkyl, heterocyclyl or heterocyclyl(C1-C6)alkyl;  R<3> is a group of the formula: <CHEM> wherein R<1><6> is H, halo, 4-OH, 4-(C1-C6 alkoxy), 4-(C3-C7 cycloalkoxy) 4-(C2-C6 alkenyloxy), 4-[(C1-C6 alkoxy)carbonyloxy], 4-[(C3-C7 cycloalkoxy)carbonyloxy], or 3-(C1-C4 alkyl)SO2NH-; and R<2><0> is H, C1-C4 alkyl, C1-C4 alkoxy, C2-C6 alkanoyl or halo; or R<3> is a group of the formula: <CHEM> wherein said groups may optionally be substituted in the fused benzene ring by C1-C4 alkyl, C1-C4 alkoxy, OH, halo or CF3; are antihypertensive agents of utility in the treatment of hypertension, heart failure and renal insufficiency.
Patent IL-95912-A0 (IL)
Title: Method for prolonging the shelf life of red blood cells
IPC: A01N1/02
Filed: 1990-10-07
Abstract: This invention provides an improved method for prolonging the shelf life of transfusible red blood cells by decreasing the effective osmolality of the suspending solution and increasing the intracellular pH of the cells prior to storage thereof. This invention also provides methods whereby the intracellular pH may be increased. These methods include collecting the cells in an anticoagulant at pH 7.0 or higher and/or washing, diluting or resuspending the cells prior to storage thereof in a biologically compatible buffered solution that contains at least one non-penetrating or substantially non-penetrating anion or non-electrolyte and is substantially free of chloride ions.
Patent IL-97206-A0 (IL)
Title: Apparatus and method for the detection of air in fluid delivery systems
IPC: G01N29/02
Filed: 1991-02-11
Abstract: An infusion device includes an infusion pump for delivering a liquid through an infusion conduit from a separate source of the liquid into a patient, a bubble detector for detecting the presence of an air bubble in the infusion conduit, and control circuitry responsive to the bubble detector for determining if the size of the air bubble is unacceptable. The control circuitry is configured to determine if during the time the air bubble is detected it advances a distance indicative of the unacceptable size, one embodiment counting the steps of a linear peristaltic infusion pump for that purpose.
Patent IL-99874-A0 (IL)
Title: Aminoglycoside composition having substantially reduced nephrotoxicity induced by the amino glycoside
IPC: A61P43/00
Filed: 1991-10-28
Abstract: This invention relates to an aminoglycoside composition having reduced nephrotoxicity induced by the aminoglycoside which comprises a selected aminoglycoside and a compound present in an effective amount selected from the group consisting of (a) at least one 7-(oxoalkyl) 1,3-dialkyl xanthine of the formula <CHEM> in which R1 and R2 are the same or different and are independently selected from the group consisting of straight-chain or branched alkyl radicals with 2 to 6 carbon atoms, cyclohexyl, straight-chain or branched chain alkoxyalkyl and hydroxylalkyl radicals; and A is a hydrocarbon radical with up to 4 carbon atoms which can be substituted by a methyl group; (b) a compound of the formula <CHEM> wherein at least one of R3 and R4 is a branched hydroxyalkyl group of the formula <CHEM> with a tertiary alcohol function, which R6 stands for an alkyl group with 1 to 3 carbon atoms and n stands for a whole number from 2 to 5, the other R3 or R4 group that may optionally be present stands for a hydrogen atom or an aliphatic hydrocarbon group R7 with up to 6 carbon atoms, whose carbon chain may be interrupted by up to 2 oxygen atoms or may be substituted with an oxo group or up to two hydroxyl groups R5 is an alkyl group having 1 to 4 carbon atoms; and (c) a suitable mixture of the foregoing.
Patent AU-PP890599-A0 (AU)
Title: Tensioning hydraulic nuts
IPC: B25B29/02
Filed: 1999-02-26
Abstract: A hydraulic tensioning system for nuts on studbolts has a puller bar and a puller buddy, which are coupled to the studbolt, and a bridge around the nut. The puller bar is internally coupled to the studbolt (and may engage the nut before the tension is applied). The nut can comprise a cone nut, which cooperates with a complementary collar or shell with a conical inner face and a spherical base washer.
Patent FI-20010637-A0 (FI)
Inventor: AALTONEN ESA JUHANI
IPC: B61B1/00
Filed: 2001-03-28
Abstract: The object of the invention is a releasing method and a releasing member for releasing a towed device from a cableway at a desired point without an assisting person or without stopping the lift. According to the method a towing member ( 2 ) connected to the towing rope ( 10 ) of the towing apparatus ( 5 ) of the cableway ( 4 ) is released from the clutch member ( 1 ) in the towed device by changing the vertical towing angle (R) between the towing member ( 2 ) and the clutch member ( 1 ) at the release point. In order to change the angle, a releasing member ( 3 ), developed for the method and mounted at the release point, is used, whereby the member has a vertical section (V) arranged intersectingly on the towing line at a height, which allows the towed device to pass below it. A safety system ( 9 ) can be connected to the releasing member, which system results in the stopping of the lift in the case that the load in the towing direction acting on the horizontal portion (V) exceeds the allowed value. By using this releasing method the dangers which are created if the release would occur too early or too late, are avoided.
Patent FI-20021015-A0 (FI)
Inventor: NIKANDER RISTO
IPC: C03B35/16
Filed: 2002-05-30
Abstract: The method for tempering a glass (G) in furnace, which includes heating section carrying the glass on rollers to heat the glass into tempering temperature, further tempering section with cooling blow jets (J), equipped with rollers (R) to transfer the glass from heating section to tempering section. The air blasting (J) blown towards the glass is produced from nozzle blocks (NB) located under rollers (R), from where the are lead upwards alongside of the rollers towards the glass (G) and directed onto the glass from suitable distance through special nozzles, (N).
Patent FI-20041654-A0 (FI)
Inventor: RAJANIEMI JAAKKO
IPC: H04Q/
Filed: 2004-12-22
Abstract: A method provides monitoring access to an information server. The method comprises receiving an attempt to access an information server. The method further comprises determining whether the information server is available. The method further comprises informing that the information server is not available, if the information server is not available. The method further comprises storing information relating to the attempt. Furthermore, a gateway, an information server, a communication system and a computer program are configured to execute the method.
Patent IL-113932-A0 (IL)
Title: A lactose repressor protein a gene coding therefor and a method for expressing and controlling the expression of said gene
IPC: C12N15/09
Filed: 1995-05-31
Abstract: In a lactose repressor protein, at least one amino acid at the position of 94, 241, 265 or 300 in the wild lactose repressor is replaced with an amino acid other than that of the wild lactose repressor, and the use thereof. The present mutant lactose repressor represses the expression of a desired gene at 30 DEG C or lower temperature, and induces the expression of a desired gene at 37 DEG C or higher temperature, and therefor can control the expression by change of a culture temperature without using an expensive inducer such as IPTG.
Patent IL-121542-A0 (IL)
Title: Methods for the preparation of taxane derivatives and novel taxane derivatives prepared thereby
IPC: C07F7/18
Filed: 1997-08-13
Abstract: Novel methods for the preparation of sidechain-bearing taxanes, comprising the preparation of an oxazoline compound, coupling the oxazoline compound with a taxane having a hydroxyl group directly bonded at C-13 thereof to form an oxazoline sidechain-bearing taxane, and opening the oxazoline ring of the oxazoline sidechain-bearing taxane so formed. Novel compounds prepared by the methods of the present invention are also provided.
Patent IL-126339-A0 (IL)
Title: Taxol derivatives
IPC: C07D/
Filed: 1998-09-24
Abstract: Compounds having the formula   <IMAGE>   wherein -OR1 comprises the C-13 side-chain of taxol and R3 comprises hydrogen, as well as a method for the preparation thereof.
Patent IL-131597-A0 (IL)
Title: Dolastatin-15 derivatives in combination with taxanes
IPC: A61K38/07
Filed: 1998-03-09
Abstract: The present invention provides compositions and methods for the treatment of cancer in a subject wherein compounds of Formula I as defined herein in combination with paclitaxel, taxotere or modified taxane or taxoid analogs provide enhanced anticancer effects over the effects achieved with the individual compounds.</PTEXT>
Patent IL-137175-A0 (IL)
Title: Fingerprinting device
IPC: G06K9/20
Filed: 1999-01-20
Abstract: The invention concerns a device for taking prints of skin tissues comprising an optical sensor (10) with an object surface (12) for receiving tissues whereof the print has to be taken and, on a fraction of the object surface, a thin transparent electrode coated with an electroluminescent dielectric layer (34). Means provide difference of potential between the tissues pressed on the sensitive layer and the transparent electrode and other means (22) form an image of the tissues pressed on the object surface, including said fraction. The imaging means provide an electronic treatment of the image which enables identification or verification by comparing with one or several stored prints by verifying the continuity of relief on the fraction and the remainder of the object surface.
Patent IL-143150-A0 (IL)
Title: A process for the preparation of n,n'-bis[2,3-dihydroxypropyl]-5[hydroxyacetyl) methylamino]-2,4,5-triiodo-1,3-benzenedicarboxamide
IPC: C07C231/12
Filed: 1999-11-25
Abstract: A novel process for the preparation of N,N'-bis[2,3-dihydroxypropyl]-5-[(hydroxyacetyl) methylamino]-2,4,6-triiodo-1, 3-benzenedi carboxamide of formula (I), commonly known as lomeprol, a novel non-ionic contrast agent which shows very good safety and contrast effectiveness.
Patent IL-147181-A0 (IL)
Title: Device comprising a number of superposed bucket conveyors for sorting flat objects
IPC: B07C3/08
Filed: 2000-07-13
Abstract: The device for sorting flat objects comprises at least one first conveyor consisting of buckets moving along a closed loop first path and a second conveyor, mechanically independent of the first conveyor, also consisting of buckets moving in a closed loop path and vertically superposed over the first path. Movement of both conveyors are synchronized by an electric shaft. Flat objects are transferred between conveyors by gravity.
Patent IL-148003-A0 (IL)
Title: Floating pharmaceutical composition comprising an active phase and a non-active phase
IPC: A61K9/00
Filed: 2000-08-02
Abstract: The invention concerns a floating pharmaceutical composition consisting of at least a first phase comprising at least a high dose active principle combined with one or several carriers and at least a second phase comprising at least a gas-generating system. The invention also concerns tablets comprising such a pharmaceutical composition and a method for preparing such tablets.
Patent IL-156201-A0 (IL)
Title: Pyrazinoquioxaline derivatives and pharmaceutical compositions containing the same
IPC: A61K31/4985
Filed: 2001-12-19
Abstract: The present invention is directed to novel compounds represented by structural Formulas (I) and (I-a):or a pharmaceutically acceptable salt thereof, wherein R<1>, R<4a>, R<4b>, R<5>, R<6>, R<7>, R<8>, R<9>, n, and X are described herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are serotonin agonists and antagonists and are useful in the control or prevention of central nervous system disorders including obesity, anxiety, depression, psychosis, schizophrenia, sleep and sexual disorders, migraine and other conditions associated with cephalic pain, social phobias, and gastrointestinal disorders such as dysfunction of the gastrointestinal tract motility.
Patent IL-158866-A0 (IL)
Title: Use of il-18 inhibitors for the treatment or prevention of sepsis
IPC: A61K47/48
Filed: 2002-05-16
Abstract: The present invention provides a method of treatment and/or prevention of sepsis and other diseases characteristic to the Systemic Inflammatory Response Syndrone (SIRS), including severe sepsis, septic shock and sepsis related to cardiac dysfunction.
Patent IL-164801-A0 (IL)
Title: Antibacterial compositions comprising metal phthalocyanines analogues
IPC: A61K31/4035
Filed: 2003-04-17
Abstract: The present invention relates to pharmaceutical compositions comprising metal phthalocyanine analogues of formula (I) and metal chelating compounds: <CHEM> having a good bioavailability and enhanced photoinactivation properties against Gram negative bacteria; and to their use for in vivo/ex vivo applications, such as blood and blood derivatives sterilization. <IMAGE>
Patent IL-166432-A0 (IL)
Title: Composition containing an androgenous 11?-halogen steroid and a progestational hormone and male contraceptive based on said composition
IPC: A61K31/565
Filed: 2005-01-20
Abstract: The invention relates to a novel chemical composition containing an androgenous 11beta-halogen steroid and the progestational hormone of formula (I), to a pharmaceutical composition containing said chemical composition and to a male contraceptive based on said pharmaceutical composition.
Patent IL-174368-A0 (IL)
Title: Fused pentacyclic polyethers
IPC: A61K31/353
Filed: 2006-03-16
Abstract: Disclosed are polycyclic polyether compounds of formula I and pharmaceutical compositions comprising such compounds. wherein R, OR1, and R2 are as defined herein. Also disclosed are methods of regulating mucus clearance in a cell, and methods of treating decreased mucus clearance or mucociliary dysfunction.
Patent IL-182871-A0 (IL)
Title: Methods for preparing pimecrolimus
Filed: 2007-04-30
Abstract: The present invention provides processes for crystallization of macrolides, specifically pimecrolimus and tacrolimus.
Patent IL-185108-A0 (IL)
Title: Processes for preparing cinacalcet hydrochloride crystal form i
Filed: 2007-08-07
Abstract: Cinacalcet salts substantially free of cinacalcet carbamate, and processes for the preparation thereof.
Patent RO-127756-A0 (RO)
Title: Cylindrical multi-hollow briquette produced of ferrous pulverous and small waste with a grain size of less than 2 mm
Inventor: INVENTATORI NEDECLARAŢI
IPC: C22B1/24
Filed: 2012-02-28
Abstract: The invention relates to a cylindrical multi-hollow briquette obtained from ferrous pulverous and small waste with a grain size of less than 2 mm, said briquette being used in ferrous metallurgy in the wind furnaces producing the refining iron or in the installations for direct reduction of iron in order to produce iron sponge. According to the invention the briquette (1) has the shape of a cylinder with a height h=40...50 mm and an outer diameter D= 70 mm, in which there were cut 7 identical tubular cavities with internal diameters d= 10 mm, placed as follows: one central cavity and six cavities whose centres are at a distance R= 20 mm in relation to the centre of the briquette (1) and at 60° to one another and it is obtained by hydraulically pressing, in a mould, a mixture having the following composition: 40...60% steel plant dust, 8...10 % furnace dust, 8...10% furnace agglomeration sludge, 5...7% iron scale sludge or iron scale with a grain size of less than 2 mm, 5...7% coal dust, 5...7% ferrous fraction of less than 2 mm of steel plant slag, 3...5% graphite, 3...5% ferro-basic concentrate obtained from steel-ore waste with grain size of less than 2 mm, 2...4% bentonite, 2...4% lime, 4...8% water, the briquette (1) showing an increase of the surface of the reaction front by 42.85% and, by the existence of the 7 cylindrical interval surfaces (3) outside the outer cylindrical surface (2), determining an increase of the reduction speed by up to 76% in relation to the common briquettes.