baber/WOPTO huggingface dataset:
Patent AU-2017268272-A1 (AU)
Title: Compositions for the delivery of tRNA as nanoparticles and methods of use therewith
Inventor: THOMAS PHILIP J
IPC: A61K31/7125
Filed: 2017-05-16
Abstract: In some aspects, the present disclosure provides a nanoparticle composition comprising tRNA and an aminolipid delivery compound. The aminolipid delivery compound may be a dendrimer, dendron, or dendritic lipid, a polymer such as a polyamide or polyester, or a lipid with one or more hydrophobic components. In some embodiments, these compositions may be administered to a patient to treat a genetic disease or disorder such as cystic fibrosis, Duchene muscular dystrophy, or cancer.
Patent AU-2017286835-A1 (AU)
Title: Compositions and methods for gene editing
Inventor: LUNDBERG ANTE SVEN
IPC: C12N15/113
Filed: 2017-06-29
Abstract: The present application provides materials and methods for treating a patient with one or more conditions associated with ANGPTL4 whether
Patent AU-2017300123-A1 (AU)
Title: Isoquinoline derivatives as PERK inhibitors
Inventor: AXTEN JEFFREY
IPC: A61P35/00
Filed: 2017-07-18
Abstract: The invention is directed to substituted isoquinoline derivatives and uses thereof. Specifically, the invention is directed to compounds according to Formula I and the use of compounds of Formula (I) in treating disease states: (I) wherein R
Patent AU-2017361116-A1 (AU)
Title: Electronic payment processing
Inventor: HADLEY STEVEN
IPC: G06Q20/02
Filed: 2017-11-14
Abstract: A payment terminal (2) is described. The payment terminal includes a payment application (6) for processing transaction requests and a web server, for example a websocket application (5) implementing a websocket server (4), for client-server communication over a communication channel with another transaction system device, for example a POS device. Transaction systems including the payment terminal (2) are also described, as are methods for a transaction system.
Patent AU-2017381657-A1 (AU)
Title: Method for in vitro glycoengineering of antibodies
Inventor: DAMS THOMAS
IPC: C07K16/00
Filed: 2017-12-19
Abstract: Herein is reported a method for the enzymatic production of an antibody with a modified glycosylation in the Fc-region comprising the steps of incubating the antibody light chain affinity ligand-bound monoclonal antibody with a glycosylation in the Fc-region with a first enzyme for a time sufficient and under conditions suitable to modify the glycosylation of the Fc-region, recovering the antibody from the antibody light chain affinity ligand, incubating the recovered antibody in solution with a second enzyme for a time sufficient and under conditions suitable to modify the glycosylation of the Fc-region to a defined form, separating the antibody with the modified glycosylation in the Fc-region from the second enzyme in a cation exchange chromatography, and thereby producing the antibody with a modified glycosylation in the Fc-region.
Patent AU-2017431234-A1 (AU)
Title: Consequent pole-type motor, electric motor, compressor, air blower, and air conditioner
Inventor: SHIMOKAWA TAKAYA
IPC: H02K1/27
Filed: 2017-09-05
Abstract: A rotor (2) has: a rotor core (21) that has a magnet insertion hole (21a) and an opening (21c); and a permanent magnet (22) that is inserted into the magnet insertion hole (21a) and that forms a first magnetic pole. When a first maximum width of the opening (21c) in a direction orthogonal to the radial direction is defined as L1 and a second maximum width of the opening (21c) in the radial direction is defined as L2, the rotor (2) satisfies L1 < L2. The distance from the opening (21c) to the magnet insertion hole (21a) is smallest at the magnetic pole center (c1) of the first magnetic pole.
Patent WO-2018145163-A1 (WO)
Title: Combineur de même bande
Inventor: ABUSHAABAN MOSTAFA
IPC: H01P5/12
Filed: 2018-02-09
Abstract: La présente invention concerne les télécommunications et en particulier l'utilisation partagée d'antennes par de multiples stations de base. Le système comprend des premier et second ports d'entrée destinés à recevoir respectivement des premier et second signaux radio. Le système comprend en outre un port de sortie, destiné à émettre un signal radio de sortie selon les premier et second signaux radio et une ou plusieurs lignes d'émission s'étendant entre les premier et second ports d'entrée et le port de sortie. Le système comprend en outre un ou plusieurs filtres coupe-bande couplés au bord aux lignes d'émission. Les filtres coupe-bande sont configurés pour filtrer les premier et second signaux radio de telle sorte que le signal de sortie comprend une ou plusieurs premières sous-bandes du premier signal radio, et une ou plusieurs secondes sous-bandes du second signal radio.
Patent AU-2018202156-A1 (AU)
Title: System and method for operating a safety-critical device over a non-secure communication network
Inventor: HELLUM PÅL LONGVA
IPC: H04L29/08
Filed: 2018-03-27
Abstract: A system and method for operating, at a near location, a safety-critical device, e.g. a weapon station, located at a far location. The system comprises a first operating input device to be operated at the near location by an operator, providing a first 5 barrier control signal; and a second operating input device to be operated at the near location by an operator, providing a second barrier control signal. The first barrier control signal is communicatively connected to a near end of a first secure communication tunnel through the non-secure communication network, and the second barrier control signal is communicatively connected to a near end of a 10 second secure communication tunnel through the non-secure communication network. A far end of the first secure communication tunnel is communicatively connected to an activating input of a first barrier circuit, and a far end of the second secure communication tunnel is communicatively connected to an activating input of a second barrier circuit. The first and second barrier circuits are configured to 15 enable operation of the safety-critical device when both the first and second barrier circuits are activated. Additional barrier circuits may be included. WO 2014/114736 PCT/EP2014/051373 Fig. 1
Patent AU-2018203979-A1 (AU)
Title: Improved lipid formulation for the delivery of nucleic acids
Inventor: AKINC AKIN
IPC: A61K48/00
Filed: 2018-06-05
Abstract: IMPROVED LIPID FORMULATION FOR THE DELIVERY OF NUCLEIC ACIDS Abstract: The invention features an improved lipid formulation comprising a cationic lipid of formula (A), a neutral lipid, a sterol and a PEG or PEG-modified lipid, where R, and R2 are independently alkyl, alkenyl or alkynyl, each can be optionally substituted, and R3 and R4 are independently lower alkyl or R3 and R4 can be taken together to form an optionally subsituted heterocyclic ring. In one embodiment, R1 and R2 are independently selected from oleoyl, pamitoyl, steroyl, linoleyl and R3 and R4 are methyl. Also disclosed are targeting lipids, and specific lipid formulations comprising such targeting lipids. N-R4 (A) o1R
Patent AU-2018204125-A1 (AU)
Title: Continuous flow separation chamber
Inventor: MURPHY MATTHEW
IPC: B04B7/12
Filed: 2018-06-08
Abstract: Continuous Flow Separation Chamber Abstract A centrifuge bowl for continuous separation of whole blood comprising: an outer body rotatable about a longitudinal axis of the centrifuge bowl, the outer body having a main body defining an interior cavity, a neck portion extending proximal to the main body, and a shoulder connecting the main body and the neck portion: a top core located within and rotatable with the outer body, the top core being coaxial with the outer body and including a chimney extending through the top core along the longitudinal axis of the centrifuge bowl; a separation region located between the top core and the outer body, rotation of the centrifuge bowl separating the whole blood within the separation region into a first blood component and a second blood component; an inlet port for introducing whole blood into the centrifuge bowl; an inlet tube fluidly connected to and extending distally from the inlet port and through the chimney, the inlet tube configured to introduce the whole blood into an introduction region; a first blood component outlet port for drawing the first blood component out of the centrifuge bowl; a first blood component extraction tube extending from the first blood component outlet port to a first blood component extraction region; a second blood component outlet port fluidly connected to the separation region and for drawing a second blood component from the centrifuge bowl; a centrifuge bowl rotary seal attached to the outer body and fluidly coupling the inlet port, first blood component outlet port, and second blood component outlet port to the outer body; and an optical sensor located on the shoulder of the outer body, the optical sensor configured to monitor an interface between the first blood component and the second blood component within the separation region, the optical sensor configured to control the operation of a first blood component pump based upon a location of the interface. 10355826_1 (GHMatters) P99886.AU.1 110 130 220 RBC Effluent Whole Blood Inlet Plasma Effluent 270 260 184 - 148 Top Core Bottom Core 210 200 16 \ O25162 16170 164 FIG. 1 225 222
Patent AU-2018204197-A1 (AU)
Title: Modular building units, and methods of constructing and transporting same
Inventor: BOWRON JULIAN
IPC: E04B1/343
Filed: 2018-06-13
Abstract: A connector assembly, having an upper connector coupled to a lower connector and a gusset plate sandwiched between the upper and lower connectors. Also, disclosed is a hoistable connector assembly, a lifting frame 5 assembly, a coupling system for modular frame units, a method for assembling a module unit using the connector assembly, and a modular frame unit and building having the connector assembly. r a
Patent AU-2018208637-A1 (AU)
Title: Hydrocarbon polymers with two alkoxysilane end groups
Inventor: MICHAUD GUILLAUME
IPC: C08F10/14
Filed: 2018-07-24
Abstract: Hydrocarbon-based polymer of formula (1) bearing alkoxysilane end groups: (R'O) 3-r(R)rSi pq Si(R)r(OR') 3-r q (1) in which: - -/ is a double or single bond; - each of R2, R3, R4 and R5 is H, a halo, an alkoxycarbonyl or an alkyl, - m and p are each from 0 to 5, - each of R and R' is an alkyl, - Z is an alkylene, optionally interrupted with COO, - q is 0 or 1, - r is 0, 1 or 2, and - n is an integer such that the number-average molar mass Mn of the polymer is from 400 to 50 000 g/mol, and its polydispersity index (PDI) is from 1.0 to 2.0. Preparation by ring-opening metathesis polymerization for 2 hours to 24 hours. Adhesive composition comprising polymer (1) and crosslinking catalyst. Bonding by assembly of two substrates using this adhesive composition.
Patent AU-2018211321-A1 (AU)
Title: Heterodyne-mimicking adapter
Inventor: GOVARI ASSAF
IPC: A61B50/00
Filed: 2018-08-03
Abstract: An adapter, for coupling a first medical instrument to a control console having a console receptacle configured for attachment thereto of a different second medical 5 instrument, includes a case, a receptacle, circuitry contained in the case and an output connector. The receptacle is configured to receive an input connector of the first medical instrument conveying modulated analog input signals from the first medical instrument. The 10 circuitry includes an analog/digital converter coupled to sample and digitize the analog input signals to generate digital samples, digital processing circuitry configured to digitally downconvert the digital samples so as to generate a baseband digital signal, and a digital/analog 15 converter configured to convert the baseband digital signal to an analog baseband signal compatible with an output of the second medical instrument. The output connector is configured to be inserted into the console receptacle and to convey the analog baseband signal to the console. ADC DSP DAC CIRCUIT CIRCUIT CIRCUIT 60 62 64 56 (HIGH-FREQUENCY ANALOG INPUT SIGNAL 70 A/D CONVERSION 72 HIGH-FREQUENCY DIGITAL SIGNAL 74 DIGITAL DOWNCONVERSION 176 78 LOW-FREQUENCY DIGITAL BASEBAND SIGNAL 80,d D/A CONVERSION 82 ANALOG BASEBAND OUTPUT SIGNAL
Patent AU-2018212429-A1 (AU)
Title: Apparatus for heating smokable material
Inventor: KAUFMAN DUANE A
IPC: A24F40/465
Filed: 2018-01-23
Abstract: Disclosed is a heating element (10, 20, 30) for use with apparatus for heating smokable material to volatilise at least one component of the smokable material. The heating element (10, 20, 30) is made of heating material that is heatable by penetration with a varying magnetic field. The heating element (10, 20, 30) has a first dimension (L) and a second dimension (T) perpendicular to the first dimension (L). The first dimension (L) extends from a first portion (11) of the heating element (10, 20, 30) to a second portion (12) of the heating element (10, 20, 30). The second dimension (T
Patent AU-2018219348-A1 (AU)
Title: Proteins binding BCMA, NKG2D and CD16
Inventor: CHANG GREGORY P
IPC: C07K16/28
Filed: 2018-02-09
Abstract: Multi-specific binding proteins that bind BCMA, the NKG2D receptor, and CD 16 are described, as well as pharmaceutical compositions and therapeutic methods useful for the treatment of cancer.
Patent AU-2018226441-A1 (AU)
Title: Improvements to Latches for Movable Barriers or the like
Inventor: SO RICHARD
IPC: G08B21/00
Filed: 2018-09-05
Abstract: Abstract A system for relaying status information of at least one movable barrier (10) to a user comprising: a. a latch assembly (140, 140a) for a movable barrier (10), wherein each latch assembly (140, 140a) comprises a latch operable between a latched condition and an unlatched condition, a sensor arrangement configured to detect the latched and/or unlatched condition of each latch, and a wireless transmitter for communicating the latched and/or unlatched condition of each latch; and b. a base unit (24) for wirelessly receiving the latched and/or unlatched condition of each latch, wherein the base unit further comprises an indicator adapted to notify the user of the latched and/or unlatched condition of each latch, and a user interface for controlling and/or operating the base unit in response to the indicator, wherein the indicator comprises at least an audible and/or visual alarm. Figure 10 -1 100 22a 20a 10a 218a 140a 12a Fg 1012a Fig. 10
Patent AU-2018253520-A1 (AU)
Title: Stable dual variable domain immunoglobulin protein formulations
Inventor: SIEDLER MICHAEL
IPC: C07K16/24
Filed: 2018-10-24
Abstract: STABLE DUAL VARIABLE DOMAIN IMMUNOGLOBULIN PROTEIN FORMULATIONS The disclosure provides stable aqueous formulations comprising an Aqueous Stable Dual Variable Domain Immunoglobulin (AS-DVD-Ig) protein. The disclosure also provides stable lyophilized formulations comprising a Lyophilized Stable Dual Variable Domain Immunoglobulin (LS-DVD-Ig) protein.
Patent AU-2018260541-A1 (AU)
Title: Thermoplastic compositions, methods, apparatus, and uses
Inventor: COLGROVE JAMES R
IPC: C08K5/20
Filed: 2018-04-27
Abstract: Thermoplastic polyurethane (TPU) compositions, methods for producing TPU compositions, methods of using TPU compositions, and apparatuses produced therefrom are disclosed. Disclosed TPU compositions include a thermoplastic polyurethane polymer, a heat stabilizer, a flow agent, and a filler material. The filler may be a glass fiber. Disclosed TPU compositions have improved thermal stability and improved flow properties suitable for injection molding of articles of manufacture having a large plurality of fine openings or pores. Articles produced from the composition have superior thermal stability, abrasion resistance, and chemical resistance. Example articles include screening members for vibratory screening machines.
Patent AU-2018260807-A1 (AU)
Title: Pharmaceutical composition for the treatment of autism
Inventor: DURHAM LYNN
IPC: A61K31/437
Filed: 2018-11-06
Abstract: Abstract The present invention relates to a pharmaceutical composition or a kit comprising o a substance capable of raising intracellular cAMP levels and o a substance capable of modulating intracellular calcium concentration. Likewise, the present invention relates a pharmaceutical composition for use in the treatment of ASD phenotype 1, the pharmaceutical composition comprising a substance capable of raising intracellular cAMP levels.
Patent AU-2018268839-A1 (AU)
Title: Detection of misfolded TAU protein
Inventor: SOTO-JARA CLAUDIO
IPC: G01N33/50
Filed: 2018-05-16
Abstract: Methods and kits are provided for amplifying and detecting misfolded tau protein from samples, for example, from patients having tauopathies such as Alzheimer's Disease, Progressive Supranuclear Palsy, and the like.
Patent AU-2018290341-A1 (AU)
Title: Data transmission in a physical downlink control channel
Inventor: HOSSEINI SEYEDKIANOUSH
IPC: H04W72/04
Filed: 2018-06-22
Abstract: Communications data having a reliability and latency threshold may be transmitted within a legacy downlink control channel. For example, a user equipment (UE) may utilize low latency services, such as ultra-reliable low latency communications (URLLC). In such cases, a base station may transmit URLLC data in a legacy physical downlink control channel (PDCCH) of a downlink transmission time interval. The UE may determine that the PDCCH includes downlink data. The downlink data may have a delay tolerance below the threshold level (e.g., URLLC data), and the determination may be based on a downlink control information (DCI) payload within the received PDCCH. The UE may then receive the downlink data within the PDCCH. In some examples, the downlink data may be received within the DCI payload. Additionally or alternatively, the DCI payload may provide an indication of resources within the PDCCH that are utilized for carrying the downlink data.
Patent AU-2018293445-A1 (AU)
Title: Decision making system and method of feeding aquatic animals
Inventor: RISHI HEMANG RAVI
IPC: A01K61/80
Filed: 2018-06-28
Abstract: The present invention relates to a method and apparatus for providing a dynamic decision- making process in relation to feeding animals in water. More particularly, the present invention relates to a method and apparatus for improving feeding and/or farming strategies used in a fish farm. According to a first aspect, there is provided a computer-implemented method for feeding one or more aquatic animals, the method comprising the steps of: receiving pre- processed sensor data in relation to the one or more aquatic animals; inputting the pre- processed sensor data into one or more learned decision-making models, wherein the one or more learned decision-making models has been trained to substantially optimise the rate and amount of food provided to the aquatic animals; determining, by the one or more learned decision-making models using the received pre-processed sensor data, feeding instructions for the one or more aquatic animals; and outputting the feeding instructions from the one or more learned decision-making models.
Patent AU-2018312816-A1 (AU)
Title: Antibodies that bind EGFR and cMET
Inventor: GEUIJEN CECILIA ANNA WILHELMINA
IPC: C07K16/46
Filed: 2018-08-09
Abstract: The invention as disclosed herein relates to bispecific antibodies that comprises a first variable domain that can bind an extracellular part of epidermal growth factor receptor (EGFR) and a second variable domain that can bind an extracellular part of MET Proto-Oncogene, Receptor Tyrosine Kinase (cMET). The antibody may comprise a common light chain, it may be a human antibody, The antibody may be a full length antibody. In some embodiments the bispecific antibody is an IgGl format antibody having an anti-EGFR, anti-eMET stoichiometry of 1:1, In some embodiment the antibody has one variable domain that can bind EGFR and one variable domain that can bind cMET.
Patent AU-2018329492-A1 (AU)
Title: Fault tolerant services for integrated building automation systems
Inventor: CASILLI CHRIS
IPC: G05B15/02
Filed: 2018-08-28
Abstract: A service accesses one or more building automation systems elements directly to collect data and provides the data to data consumers.
Patent AU-2018344767-A1 (AU)
Title: Improved heat treatable titanium alloy
Inventor: WU XINHUA
IPC: C22C14/00
Filed: 2018-10-08
Abstract: A "modified" meta-stable  titanium alloy that, apart from carbon content, corresponds to the composition range for standard Beta-C titanium alloy. The modified alloy comprises vanadium, chromium, molybdenum, zirconium, aluminium, with maxima for oxygen, iron, nitrogen, hydrogen, yttrium, and other elements (apart from carbon and titanium), with a balance (apart from carbon) of titanium. The modified alloy has carbon present at a stable total carbon level sufficiently in excess of 0.05 wt.% achieving an improvement in the mechanical properties of UTS, DSS and fatigue strength in threaded regions, relative to standard Beta-C alloy with a specified carbon level below 0.05 wt.%, with a maximum carbon content controlled so as to preclude carbide formation having a detrimental effect on the level of fatigue strength.
Patent AU-2018349089-A1 (AU)
Title: Security risk identification in a secure software lifecycle
Inventor: BHALLA NISHCHAL
IPC: G06F21/57
Filed: 2018-10-12
Abstract: A system and method for security risk identification in a secure software lifecycle. A knowledge database has a plurality of security elements which are identified for a particular software application depending on software environment and prioritized in a task list. Code vulnerabilities are identified using code scanners, with security requirements updated based on identified vulnerabilities, lack of vulnerabilities for weaknesses covered by a code scanner, potential weaknesses not adequately covered by code scanners, and software environment changes.
Patent AU-2018355245-A1 (AU)
Title: Soft tissue repair implants comprising hydroxybutyrate
Inventor: CRAPO PETER MAUGHAN
IPC: A61L31/16
Filed: 2018-10-24
Abstract: Articles and methods involving soft tissue repair implants comprising 2- hydroxybutyrate, 3-hydroxybutyrate, 4-hydroxybutyrate, and/or their conjugate acids are generally provided. The 2-hydroxybutyrate, 3-hydroxybutyrate, 4-hydroxybutyrate, and/or the conjugate acid(s) of 2-hydroxybutyrate, 3-hydroxybutyrate, and 4- hydroxybutyrate may be provided in a therapeutically-effective amount for reducing or preventing microbial infection.
Patent AU-2018365175-A1 (AU)
Title: Compositions and methods for enhancing visual function
Inventor: ISACOFF EHUD Y
IPC: C07K14/72
Filed: 2018-11-13
Abstract: The present disclosure provides a method of restoring or enhancing visual function in an individual, the method comprising administering to the individual a nucleic acid comprising a nucleotide sequence encoding one or more of a medium wavelength cone opsin (MW-opsin), a long wavelength cone opsin (LW-opsin), and a short wavelength cone opsin (SW-opsin). One or more of the MW-opsin, LW-opsin, and SW-opsin is expressed in a retinal cell in the individual, thereby restoring or enhancing visual function.
Patent AU-2018367945-A1 (AU)
Title: Methods for treatment of interstitial cystitis
Inventor: KELLY MELANIE
IPC: A61K31/015
Filed: 2018-11-14
Abstract: The present application relates to methods and uses of CB2 target agent local anaesthetics such as beta-caryophyllene for treatment of interstitial cystitis in a subject, optionally together with the administration or use of an additional agent for treating interstitial cystitis such as dimethyl sulfoxide (DMSO) or methylsulfonylmethane (MSM).