baber/WOPTO huggingface dataset:
Patent WO-2023070043-A1 (WO)
Title: Compositions and methods for targeted editing and evolution of repetitive genetic elements
Inventor: ISAACS FARREN
IPC: C12N15/113
Filed: 2022-10-20
Abstract: Compositions and methods for genomic engineering are described. It has been discovered that introns, preferably self-splicing introns, can be introduced into repetitive genomic sequences to form a unique genetic address that facilitates insertion or recombination of a template containing a desired sequence within the repetitive genomic sequence. Nucleic acid compositions such as polynucleotides including a sequence encoding an intron, donor oligonucleotides, gene editing technologies, and methods of use thereof are described. In particular, methods of performing targeted editing and randomized diversification to enable continuous evolution of target sites (e.g., repetitive genomic elements) are disclosed. The compositions and methods are especially useful for engineering, selection, and identification of cell variants exhibiting a desired phenotype.
Patent WO-2023150038-A1 (WO)
Title: Dispositif de balayage 3d rotatif pour enregistrement sans contact en décubitus ventral
Inventor: PRESTON SAMANTHA
IPC: A61B5/055
Filed: 2023-01-24
Abstract: L'invention concerne des systèmes et des procédés utilisés pour effectuer un balayage 3D sans contact du visage d'un patient en décubitus ventral. Dans certains cas, les systèmes comprennent un dispositif de balayage 3D rotatif pour capturer des points de données spatiales 3D du visage du patient et une trame de référence. Les modèles maillés numériques 3D sont générés à partir des points de données spatiales 3D. Un modèle maillé numérique 3D du patient est enregistré avec un modèle 3D du patient, et un modèle maillé numérique de la trame de référence est enregistré avec un modèle 3D de la trame de référence. Le dispositif de numérisation 3D peut comprendre un dispositif de balayage 3D rotatif portatif ou un dispositif de balayage 3D rotatif mécanique.
Patent WO-2023164149-A1 (WO)
Title: Radioisotope power system for vehicle
Inventor: MORRISON CHRISTOPHER
IPC: B60L50/90
Filed: 2023-02-24
Abstract: Radioisotope power system and propulsion system technologies to increase the energy efficiency, mass efficiency, and duration capability of a vehicle during operation. A radioisotope power system includes a radioisotope power unit that emits a plurality of radiation particles and is configured to directly or indirectly provide power, propulsion, or both power and propulsion of a vehicle. The radioisotope power system can further include a thermoelectric generator coupled to the radioisotope power unit and configured for coupling to at least one thruster. The radioisotope power system can further include an optional radiation shield configured to block a first radiation particle of the plurality of radiation particles. The radioisotope power unit can include one or more radioisotopes. The one or more radioisotopes can include an alpha emitting isotope, a beta emitting isotope, a gamma emitting isotope, or a combination thereof.
Patent WO-2023196106-A1 (WO)
Title: Système de régulation de température de patient ayant un ou plusieurs intervalles de point de contrôle
Inventor: GRACE STEFANIE
IPC: A61F7/00
Filed: 2023-03-20
Abstract: Appareil permettant de réguler une température d'un patient ou d'un dispositif thermique pendant une procédure thérapeutique, l'appareil comprenant un circuit de fluide pour fournir un fluide de thérapie au patient ou au dispositif thermique; et un dispositif de commande conçu pour commander un écoulement du fluide de thérapie à travers le circuit de fluide; et pour commander un taux de changement de température du fluide de thérapie. Le dispositif de commande est conçu pour générer un ou plusieurs intervalles de point de contrôle au niveau desquels le taux de changement de température du fluide de thérapie est mis en pause pour permettre à un clinicien d'évaluer la procédure thérapeutique.
Patent WO-2023196481-A1 (WO)
Title: Gestion de la transmission de petites données avec un équipement utilisateur
Inventor: WU CHIH-HSIANG
IPC: H04W72/23
Filed: 2023-04-06
Abstract: Un réseau d'accès radio (RAN) et un équipement utilisateur (UE) peuvent mettre en œuvre un procédé de gestion des petites transmissions de données (SDT). Le procédé comprend les opérations consistant à : (i) déterminer que l'UE doit fonctionner dans un état d'un protocole de contrôle des ressources radio dans lequel l'UE n'est pas connecté au RAN (704) ; (ii) générer, en fonction au moins de la prise en charge par l'UE d'un premier type de SDT qui repose sur une procédure d'accès aléatoire et/ou d'un deuxième type de SDT qui repose sur une ressource précédemment allouée à l'UE, un message qui amène l'UE à communiquer de petites données conformément à une capacité de l'UE (706, 708 et 710) ; et (iii) transmettre le message à l'UE (712).
Patent WO-2023225157-A1 (WO)
Inventor: CHI WANLI
IPC: G02B27/01
Filed: 2023-05-18
Abstract: A waveguide may include a substrate and an array of beam splitters embedded within the substrate, where each beam splitter within the array of beam splitters does not fully transect the substrate. Various other devices, systems, and methods of manufacture are also disclosed.
Patent WO-2023239908-A1 (WO)
Inventor: GLASSER CHAD
IPC: A61K31/198
Filed: 2023-06-09
Abstract: The present invention relates to a method of treating a mitochondrial disease in a patient in need thereof by administering Compound (I), a stimulator of soluble guanylate cyclase (sGC) at certain dosages either alone or in combination therapy.
Patent WO-2024006164-A1 (WO)
Title: Systèmes et procédés de robot aérien industriel
Inventor: MELCHER THOMAS W
IPC: B64U30/24
Filed: 2023-06-23
Abstract: L'invention concerne un aéronef qui a une flèche, un ensemble de propulsion couplé à une première extrémité de la flèche, et une première aile couplée à une seconde extrémité de la flèche. La première aile peut être couplée à la flèche par une (première) articulation articulée. L'ensemble de propulsion peut être couplé à la flèche par une (seconde) articulation articulée. Les articulations articulées peuvent fournir divers ajustements entre la ou les ailes et la flèche (par exemple, rangée, déployée, anhédrique, dièdre, balayage, angle d'attaque, commande de pas collectif, commande de pas cyclique, etc.) et entre le système de propulsion et la flèche (par exemple, pour se déplacer entre un vol vertical et un vol horizontal). Une charge utile peut être reliée à la flèche avec l'une des articulations articulées, ce par quoi l'articulation articulée règle une position de la charge utile pendant le vol pour maintenir des caractéristiques de vol souhaitées et stabiliser la charge utile.
Patent WO-2024015305-A1 (WO)
Title: Pressure cuff overtightening detection algorithm
Inventor: MORSY YASSER
IPC: A61B5/022
Filed: 2023-07-10
Abstract: A system includes a hardware unit that stores signal distortion detection code. The code causes the system to execute steps of a method for evaluating the fit and placement of a hemodynamic sensor. The method includes obtaining hemodynamic data from the hemodynamic sensor and determining an arterial pressure waveform based on the hemodynamic data. A distortion score is determined based on one or more features extracted from the arterial pressure waveform and a weighting module. The method includes selectively invoking a sensory alarm based on a comparison of the distortion score to a predetermined criterion or predetermined criteria.
Patent WO-2024020088-A1 (WO)
Title: Robotic hand-held surgical instrument systems and methods
Inventor: VANDYKEN BENJAMIN
IPC: A61B34/30
Filed: 2023-07-19
Abstract: A system is provided comprising a surgical robotic system for use with a tool. In some versions, the robotic instrument comprises a hand-held portion to be held by a user and a tool support movably coupled to the hand-held portion to support the tool. The robotic system further includes an actuator assembly operatively attached to the tool support and the hand-held portion and configured to move the tool support relative to the hand-held portion in a plurality of degrees of freedom. The robotic system may include a handle alignment member extending from the hand-held portion. At least a portion of the handle alignment member and a tool plane defined by the tool are aligned when the tool support has an optimal range of motion relative to the hand-held portion.
Patent WO-2024026031-A1 (WO)
Title: Programmation automatisée basée sur des signaux ecap
Inventor: MUELLER JEREL K
IPC: A61N1/36
Filed: 2023-07-27
Abstract: L'invention concerne des systèmes, des dispositifs et des techniques pour analyser des signaux ECAP pour déterminer un seuil pour une thérapie. Dans un exemple, un système comprend des circuits de traitement configurés pour recevoir une valeur d'amplitude maximale pour une pluralité d'impulsions de stimulation, des circuits de génération de stimulation de commande pour commencer la délivrance de la pluralité d'impulsions de stimulation à une valeur d'amplitude initiale inférieure à la valeur d'amplitude maximale et augmenter de manière itérative une valeur d'amplitude ultérieure d'une impulsion de stimulation suivante de la pluralité d'impulsions de stimulation jusqu'à la valeur d'amplitude maximale, recevoir, pour chaque impulsion de stimulation de la pluralité d'impulsions de stimulation, des informations de signal ECAP, déterminer, à partir des informations de signal ECAP, des valeurs caractéristiques d'ECAP, et déterminer, sur la base des valeurs caractéristiques d'ECAP et pendant la délivrance des impulsions de stimulation avec des valeurs d'amplitude augmentant de manière itérative, au moins un seuil à partir duquel une ou plusieurs valeurs de paramètre de stimulation pour des impulsions de stimulation ultérieures sont déterminées.
Patent WO-2023141391-A1 (WO)
Inventor: HAMBLET ROBERT MARTIN
IPC: H04L9/32
Filed: 2023-01-12
Abstract: L'invention concerne des procédés et/ou des systèmes destinés à une distribution sélective des données vers des composants d'identité installés dans les dispositifs clients. Les systèmes comprennent un serveur de gestion de justificatifs d'identité, un modem de réseau et/ou un composant d'identité. Les procédés comprennent l'établissement des communications entre un serveur de gestion de justificatifs d'identité et un composant d'identité.
Patent WO-2023245124-A1 (WO)
Inventor: TREADO PATRICK
IPC: G01N21/31
Filed: 2023-06-15
Abstract: L'invention concerne des systèmes et des procédés de détection et de surveillance de plaies et d'agents pathogènes dans des plaies par imagerie chimique moléculaire. Les systèmes peuvent comprendre un capteur d'image conçu pour collecter des données d'image à partir de photons ayant interagi provenant d'une plaie qui est éclairée avec une pluralité de longueurs d'onde de lumière, un processeur conçu pour analyser les données d'image et identifier un ou plusieurs agent pathogène parmi une quantité d'agents pathogènes, une identité d'agent pathogène, un état de perfusion ou un état de fluide d'une plaie sur la base des données d'image.
Patent WO-2022150857-A1 (WO)
Inventor: PAUNA RALUCA
IPC: G01N21/01
Filed: 2021-02-04
Abstract: Health i-Bot est une innovation dans le domaine de la micro-électronique numérique et le sous-domaine des capteurs optiques appliqués aux tests médicaux, qui font partie du domaine biomédical. Cette innovation comprend un appareil et un procédé pour lire n'importe quelle image de n'importe quel résultat de test médical et pour transférer l'image numérisée à un module couplé à n'importe quel type de système d'informations de santé. L'appareil a des capteurs optiques installés dans une circuiterie spécifique dans le but de lire attentivement n'importe quelle image résultant de n'importe quel test d'investigation spéciale, comprenant des tests sérologiques. L'appareil et le procédé augmentent la précision et la validité du diagnostic médical en réduisant l'intervention humaine et les erreurs d'interprétation. L'appareil est conçu avec deux options : utilisateur unique/lecteur unique et utilisateurs multiples/lecteurs multiples.
Patent DK-201570722-A1 (DK)
Title: Tip seal
Inventor: CRUM DANIEL R
IPC: F04C27/00
Filed: 2015-11-09
Abstract: A tip seal for scroll wraps in a scroll compressor is provided. The tip seal may include surface features to form a tortuous flow path in a seal groove of a scroll wrap. The surface features can help form one or more contraction and/or expansion areas in the tortuous flow path. The tortuous flow path can help provide resistance to fluid flow and help reduce leakage through the seal groove
Patent DK-201670595-A1 (DK)
Title: Configuring context-specific user interfaces
Inventor: WILSON ERIC LANCE
IPC: G06F3/0484
Filed: 2016-08-08
Abstract: Techniques for configuring context-specific user interfaces for use with a portable multifunction device are disclosed. The context-specific user interfaces provide indications of time and, optionally, a variety of additional information. The methods provided herein allow for configuring such user interfaces, e.g., at a first device coupled via wireless communication to a second device. Further disclosed are non-transitory computer-readable storage media, systems, and devices configured to perform the methods described herein.
Patent DK-202100425-A1 (DK)
Title: Disinfection Device
Inventor: FLEMMING KJÆR THINGGAARD
IPC: A61L2/24
Filed: 2021-04-28
Abstract: A disinfection unit (2) configured to be operated in a room (16) having a ceiling (20) is dis-closed. The disinfection unit (2) comprises one or more nozzles (8, 8', 8'') each being arranged to generate a jet (12) and hereby spray a disinfection fluid into the room (16). The disinfection unit (2) comprises a control unit configured to calculate a quantity of disinfection fluid to be sprayed into the room (16) on the basis of a predefined required degree of purity. The disinfection unit (2) comprises a detection unit (34) arranged and configured to detect a height (H1, H2, H3) of the room (16).
Patent PH-12014501553-A1 (PH)
Title: Dpa-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form
Inventor: MAINES TIMOTHY J
IPC: A61P9/00
Filed: 2014-07-04
Abstract: DPA-enriched pharmaceutical compositions of polyunsaturated fatty acids in free acid form, therapeutic methods for their use, and processes for refining the compositions from fish oil are presented. Also provided are methods of treating hypertriglyceridemia (200 mg/dL - 500 mg/dL) by adjunctive administration of a statin and the pharmaceutical compositions described herein. Further treatment methods include, inter alia, treatments to increase plasma EPA:AA ratios, treatments to decrease ApoCIII levels, and treatments to reduce or prevent resistance to platelet aggregation inhibitors.
Patent PH-12014501945-A1 (PH)
Title: Neurogenesis screening method and system using adipose tissue derived stem cells
Inventor: CHENZHONG KUANG
IPC: G01N33/50
Filed: 2014-08-29
Abstract: Provided herein are methods for identifying a neurogenesis-modulating compound, comprising: culturing adipose-derived stem cells (ADSCs) in the presence of a candidate compound; and determining the extent of neurogenesis in the ADSCs and systems for identifying a neurogenesis modulating compound. Also provided are methods of promoting neurogenesis in ADSCs.
Patent PH-12015500109-A1 (PH)
Title: Plant for dry conveying of slag and/or heterogenous materials
Inventor: MARIO MAGALDI
IPC: F23J1/02
Filed: 2015-01-20
Abstract: A transport system for the transport of combustion waste, comprising: - a belt conveyor for transporting the waste, arranged at the bottom of a combustion chamber and apt to transport the waste onto a transport surface (311) movable along a longitudinal direction of advancement; and - side boards (81, 82) for containing the waste in a transport region (80), arranged above said transport surface, rotably connected to a casing of the conveyor and bearing wearable members (811, 812) apt to establish a sliding seal with lateral fins (312, 313) of the movable transport surface of the conveyor belt, so that the transported material be confined in the transport region defined by said movable transport surface and by said boards bearing the wearable members.
Patent PH-12015502154-A1 (PH)
Title: Composition for oral cavity
Inventor: TAKAYUKI ONIKI
IPC: A61K8/63
Filed: 2015-09-15
Abstract: Provided is a composition for the oral cavity, said composition exerting a high anti-inflammatory effect and having an excellent formulation stability. The composition for the oral cavity comprises: component (A) that is one or more kinds of lactam compounds selected from the group consisting of pyrrolidonecarboxylic acid, 6-oxo-2-piperidinecarboxylic acid, 3-(2-oxo-1-azepanyl)propanoic acid and salts thereof; and component (B) that is an anti-inflammatory agent.
Patent PH-12016500860-A1 (PH)
Title: Arrangement of a communication coil and an induction charging coil
Inventor: WEI HUANG
IPC: H01F38/14
Filed: 2016-05-10
Abstract: An apparatus including a first layer having a first coil; a second layer having a second coil, where the first and second coils are stacked relative to each other and configured to be located at an aperture of a housing member including electrically conductive material; and a third layer located under the second layer. The third layer includes a ferrite member located under the second coil such that the second coil is between the first coil and the ferrite member. The first coil or the second coil has a substantially "8" shape.
Patent PH-12016501644-A1 (PH)
Title: Binding proteins and methods of use thereof
Inventor: KALYANI MONDAL
IPC: A61K39/395
Filed: 2016-08-17
Abstract: The present disclosure provides binding proteins, such as antibodies, that bind beta klotho, including human beta klotho, and methods of their use.
Patent PH-12017000075-A1 (PH)
Title: Reception device, gaming machine, and dealer replacement device
Inventor: JUNPEI SATO
IPC: G07F17/32
Filed: 2017-03-13
Abstract: The present invention provides a reception device, which comprises an operation device performing a variety of operations, an obstacle checking device checking the obstacle in the monitoring area which includes the motion range of the operation device, and a control device simulating the operation path of the operation device in advance before the operation device performs an action and during the process of performing the action, and if there is an obstacle in the simulated operation path, a control is performed to cause the operation device to perform the operation corresponding to the abnormal state.
Patent PH-12017501067-A1 (PH)
Title: Dihydroindolizinone derivative
Inventor: TANAKA MOTOYUKI
IPC: C07D471/04
Filed: 2017-06-08
Abstract: A compound represented by general formula (I) (wherein all symbols are as defined in the description) or a salt, solvate, N-oxide form or prodrug thereof is a potent FXIa inhibitor, has excellent oral absorption properties and kinetics in blood, can exert a potent anti-coagulation activity over a long period of time after being administered orally, and has a discrepancy between the anti-coagulation activity thereof and the CYP-inhibiting activity thereof. Therefore, the compound or the salt, solvate, N-oxide form or prodrug thereof can be used as an efficient prophylactic and/or therapeutic agent for vascular occlusive diseases.
Patent PH-12017501692-A1 (PH)
Title: Solid forms of menaquinols
Inventor: BIANCHI DAVIDE
IPC: C12P7/22
Filed: 2017-09-15
Abstract: Disclosed are solid forms of menaquinol and processes for obtaining them by chemical or enzymatic reduction of menaquinone. Said solid forms possess high stability to oxidation which allows effective use of menaquinol in the most common formulations wherein vitamin K2 is used.
Patent PH-12018500175-A1 (PH)
Title: Modular container house building structure
Inventor: TSAI CHAO-LUNG
IPC: E04B1/348
Filed: 2018-01-23
Abstract: An architectural structure of a modular container house includes: a building body with plural floors each having at least one accommodating space with an external opening; at least one external access area longitudinally disposed at the building body, and each accommodating space being communicated with external access area; and plural container houses, respectively and movably disposed in the accommodating spaces through the openings, and at least one side board of each container house can be spread open and placed horizontally on a ground of each accommodating space, so that the interior of each container house is communicated with each respective accommodating space.
Patent PH-12018500318-A1 (PH)
Title: Toner cartridge having a movable projection for providing installation feedback to an image forming device
Inventor: BAYUBAY MICHAEL NUESTRO
IPC: G03G21/18
Filed: 2018-02-13
Abstract: A toner cartridge according to one example embodiment includes a housing having a toner reservoir. An outlet port faces downward on a front of the housing near a first side of the housing. A linkage is positioned on the first side of the housing and has an engagement surface that is accessible at the rear of the housing. A projection is positioned on the first side of the housing and is movable between a first position and a second position. The projection is operatively connected to the linkage such that the projection moves upward from the first position to the second position when the engagement surface receives a forward force that is toward the front of the housing. The projection extends outward sideways from the first side when the projection is in the second position.
Patent PH-12018500990-A1 (PH)
Title: Metal plate having hollow tubes sandwiched therin and its use
Inventor: ZHANG YUE
IPC: E04C2/30
Filed: 2018-05-08
Abstract: Disclosed are a metal plate having hollow tubes sandwiched therein and its use. The metal plate sandwiching hollow tubes (3) comprises a first panel (1), a second panel (2) and a plurality of hollow tubes (3) between the first panel (1) and the second panel (2). Gaps are provided between the hollow tubes (3). The hollow tubes (3) are connected to the first panel (1) and the second panel (2) by soldering. The metal plate is a material used for building structures, vehicles, ships, aircrafts, aerospace equipment, containers, bridges, roads, tunnels, rail foundations, furniture, culverts, vacuum tubes or luggage materials. The metal plate having the hollow tubes sandwiched therein has the advantages of light weight, high strength, small stress, high temperature resistance, pressure resistance, heat insulation, heat preservation and vibration isolation, and ensures that the metal plate will not deform due to heat differences and ensures the service life.
Patent PH-12018501136-A1 (PH)
Title: System, method and device to optimize the efficiency of the combustion of gases for the production of clean energy
Inventor: PIMENTEL MARCELO FERNANDO
IPC: F23C99/00
Filed: 2018-05-30
Abstract: The present invention refers to a system, a method and a device to optimize the efficiency of the combustion of gases for the production of clean energy comprising a magnetic nucleus (30) and inlet and outlet ducts (41a, 42a), the inlet and outlet ducts (41a, 42a) being configured to receive gases, the gases alternately establishing flows between the inlet ducts (41a) and the outlet ducts (42a) and vice- versa, the magnetic nucleus (30) being configured to generate and to expose the gases within the inlet and outlet ducts (41a, 42a) to magnetic fields (35), the alternation of flows between the inlet and outlet ducts (41a, 42a) and the exposure to magnetic fields (35) promoting acceleration of the hydrogen atoms and ions of oxygen and argon, promoting the reduction of the radii of the orbits of the electrons of the hydrogen around their nuclei and provoking the release of potential energy of the electrons and corresponding increase of the kinetic energy of the nuclei of the gas molecules, in such a way to optimize (increase) the heating power of the gases (201, 202).