baber/WOPTO huggingface dataset:
Patent DE-69531387-D1 (DE)
Inventor: BOUT ABRAHAM
IPC: C07K14/52
Filed: 1995-08-15
Granted: 2003-09-04
Abstract: The invention provides novel vectors derived from adenovirus which are specifically suitable for use in methods of gene therapy. <??>The vectors have a deletion compared to wild-type adenovirus in that the E1 region is not present in a functional manner. <??>Additionally the vectors are characterized in that they do contain a part of the E3 region of adenovirus which is biologically functional. This results in vectors which do normally not lead to expression of adenoviral proteins, but which in the cases where such proteins do become expressed will repress the host's immunological response to said proteins. Thereby host cells infected (provided) with the vector will live longer. Therefor the product introduced into said cells providing the therapy will be produced in larger amounts, or at least for a prolonged period. Preferably the vector comprises genetic information for antisense therapy, or for genes which will combat tumors, such as genes encoding cytokines, preferably IL-1, or so called suicide genes, such as Herpes Simplex Virus thymidine kinase. <??>Methods for producing said vectors and methods of gene therapy or uses therein are also disclosed.
Patent DE-69535424-D1 (DE)
Inventor: ESTULIN WALTER
IPC: H04B1/40
Filed: 1995-07-17
Granted: 2007-04-26
Abstract: A subscriber unit of a time division multiple access (TDMA) radiotelephone system is, from a power consumption standpoint, reconfigured in each time slot of a TDMA frame to a power consumption tessellation in which subscriber unit circuit components not needed for communication signal processing in that time slot are powered down, and other components are powered up.Some circuit components are powered down by switching their power supply circuits. In order to minimize the extent of circuitry that must be provided to distribute power consumption control signals, other techniques (which utilize circuitry provided for other purposes), such as clock frequency control or power down commands, also are utilized to modify controlled circuit component power consumption without actually controlling power supply circuits. Loop connection length between the subscriber unit and the subscriber's telephone set, or other terminal equipment, is limited to a length which is much less than the length of a radio link on which the subscriber unit operates. Programmable ring frequency logic controls the frequency of a ringing signal generator, and a high frequency ring control signal is switched on and off in the cadence of ringing operation. Also an expansion header is provided to enable serving plural subscriber loop circuits with the same radio equipment for reducing per line power consumption.
Patent DE-69601941-D1 (DE)
Inventor: EVERETT DAVID
IPC: G07F7/08
Filed: 1996-06-28
Granted: 1999-05-06
Abstract: A value transfer system using integrated circuit cards for exchanging electronic cash in off-line transactions employs cryptographically secure message protocols. Cards are loaded each with two schemes from a series and interaction between cards determines and uses the oldest scheme shared by the cards, causing one card to switch schemes irrevocably if that common scheme is its second scheme. In this way, a switch to a new scheme can migrate through the system.
Patent DE-69604292-D1 (DE)
Inventor: BOLLINI JEAN
IPC: B62M9/12
Filed: 1996-07-01
Granted: 1999-10-21
Abstract: PCT No. PCT/FR96/01015 Sec. 371 Date Dec. 22, 1997 Sec. 102(e) Date Dec. 22, 1997 PCT Filed Jul. 1, 1996 PCT Pub. No. WO97/02149 PCT Pub. Date Jan. 23, 1997An drive device (10) of a bicycle wheel comprises a first sub-assembly (23) with a freewheel (14) secured to one of the frame mounting brackets (20), and a second sub-assembly (52) supporting the hub (12), which is supported by the other mounting bracket (18) by means of a tube (76). A first transmission sleeve (44) secured to the freewheel is designed to cooperate by insertable engagement with a second transmission member (72) fixed to the hub (12) to couple or uncouple the mechanical link between the freewheel (14) and the hub (12) when the second sub-assembly (52) is respectively fitted or removed. The wheel can thus be replaced leaving the drive freewheel (14), transmission chain and derailleur in place.
Patent DE-69611669-D1 (DE)
IPC: B66C1/22
Filed: 1996-04-16
Granted: 2001-03-01
Abstract: The yoke has a beam (1) of I-shaped cross section with two flanges (11,12) which are parallel and on each side of the beam. A connector eye (2) is provided and load suspension hooks (3) are threaded onto the lower part of the beam. Each hook has parallel plates (30) which are fastened together with a spacing between and each define a cut-out in the shape of a T to allow passage of the lower flange of the beam. The hooks are fixed in place by pins extending across apertures (38) in the hooks and similar apertures in the beam. The lower edge of each of the hook lugs (37) contact the lower flange of the beam to support the hooks. the lower edge of each lug is curved.
Patent DE-69619248-D1 (DE)
Inventor: ROE CARROLL
IPC: D21H17/14
Filed: 1996-07-25
Granted: 2002-03-21
Abstract: A lotion composition for imparting a soft, lubricious, lotion-like feel when applied to tissue paper in amounts as low as from about 0.1 to about 15% by weight, and tissue paper treated with such lotion compositions are disclosed. The lotion composition comprises a liquid polyol polyester emollient and an immobilizing agent to immobilize the liquid polyol polyester emollient on the surface of the tissue paper web and optionally a hydrophilic surfactant to improve wettability when applied to toilet tissue. Because less lotion is required to impart the desired soft, lotion-like feel benefits, detrimental effects on the tensile strength and caliper of the lotioned paper are minimized or avoided.
Patent DE-69625062-D1 (DE)
Inventor: SKABORN JOHAN
IPC: G01N35/10
Filed: 1996-04-24
Granted: 2003-01-09
Abstract: PCT No. PCT/SE96/00537 Sec. 371 Date Jan. 9, 1998 Sec. 102(e) Date Jan. 9, 1998 PCT Filed Apr. 24, 1996 PCT Pub. No. WO97/00450 PCT Pub. Date Jan. 3, 1997To interrupt the current to the drive motor (3) of a motor-driven arm (1) which carries a pipette (2) when something or someone unintentionally contacts the pipette (2) during its movement, the arm 1) has a lower, rigid part (5), and an upper, flexible part (6) which, at its one end, carries the pipette (2) and, at its other end, is rigidly connected to the lower arm part (5). The upper, flexible part (6) is in releasable contact with the lower, rigid part (5) at the end that carries the pipette (2), and is adapted to, at least partially, the released from that contact when something or someone unintentionally contacts the pipette (2) during its movement. A detecting means (9) is adapted to detect when the upper, flexible part (6), at least partially, is released from the contact with the lower, rigid part (5) and in response hereto cause a switch to brake the current to the drive motor (3) for the arm (1).
Patent DE-69633222-D1 (DE)
Inventor: WOOD RAY W
IPC: A61K49/00
Filed: 1996-02-23
Granted: 2004-09-30
Abstract: There is disclosed an aerosol comprising droplets of an aqueous dispersion of nanoparticles, said nanoparticles comprising insoluble therapeutic or diagnostic agent particles having a surface modifier on the surface thereof. There is also disclosed a method for making the aerosol and methods for treatment and diagnosis using the aerosol.
Patent DE-69636368-D1 (DE)
Inventor: TICKLE DEXTER
IPC: A63F13/219
Filed: 1996-08-29
Granted: 2006-08-31
Abstract: A device particularly for use with a computer comprises a housing for location at least partly between two fingers of a user's hand and an electronic circuit mounted on a board within the housing. The circuit includes a switch responsive to pressure selectively to open and close an electronic circuit, and conductive elements arranged on the board mounting the electronic circuit. A first control element is mounted with the housing and responsive to finger pressure such that pressure applied to the first control element causes the element to operate the switch. The first control element is movable with respect to a hinge such that finger action acts to cause the control element to swivel as a trigger about the hinge and thereby interact with the switch. The second control element includes a flexible material mounted such that pressure applied to the flexible material in different directions and positions acts to change the electrical relationship between the conductive elements on the board and thereby vary an output signal from the electronic circuit. The rear portion of the housing includes a receptacle for receiving removable battery means for powering the electronic circuit. There is an infra-red output signal transmitted to a receiver for operating the computer. The first control element is located substantially below the second control element, and the first control element being in a bottom face of the housing.
Patent DE-69707176-D1 (DE)
Inventor: JELLEMA SJOERD HETTE
IPC: C12M1/26
Filed: 1997-03-10
Granted: 2001-11-15
Abstract: The present invention provides an improved method of dosing cream yeast wherein the cream yeast to be dosed is kept under a pressure above atmospheric at least for a proportion of the time during passage from a storage container to the dosing valve.
Patent DE-69713782-D1 (DE)
Inventor: HAWLEY ANTHONY ARTHUR
IPC: A45D8/00
Filed: 1997-08-07
Granted: 2002-08-08
Abstract: PCT No. PCT/GB97/02134 Sec. 371 Date Oct. 21, 1998 Sec. 102(e) Date Oct. 21, 1998 PCT Filed Aug. 7, 1997 PCT Pub. No. WO98/06295 PCT Pub. Date Feb. 19, 1998Hair styling apparatus comprising two combs (1) each having a curvilinear spine (4) and joined together by two or more elasticated material ties (2), each releasably connected to the spine of one or each comb by complementary interchanging means of the ties and the combs. In a preferred arrangement, three ties are provided, the connection points of these being substantially equi-spaced along the length of the respective spine.
Patent DE-69716720-D1 (DE)
Inventor: EATON BRUCE
IPC: C07C29/44
Filed: 1997-02-25
Granted: 2002-12-05
Abstract: This invention discloses an improved method for the [2+2+2] cyclotrimerization reaction in aqueous solutions using a water soluble transition metal catalyst.
Patent DE-69721795-D1 (DE)
Inventor: POLYAK BELA
IPC: C12N11/04
Filed: 1997-09-05
Granted: 2003-06-12
Abstract: Disclosed herein is a novel continuous production process for the preparation of L(-) malic acid (the naturally occurring enantiomer of malic acid) from fumaric acid with the use of a novel immobilized biocatalyst. The long shelf life novel immobilized biocatalyst comprising living or killed cells or purified enzymes suitable for use in the method of the invention is also comprised in the invention.
Patent DE-69724420-D1 (DE)
Inventor: SCHULTZ ROBERT
IPC: A61K9/00
Filed: 1997-04-21
Granted: 2003-10-02
Abstract: A method for inhalation of a dry powder drug includes the steps of providing a dry powder drug composition having a drug particle size of from about 1-7 microns and a mass median aerodynamic diameter of the delivered aerosol of from about 3.5 to 5.5 microns. This composition is loaded into an inhaler which is generally flow rate independent, and with the inhaler having an inspiration flow resistance of about 0.12 to 0.21 (cmH2O)+E,fra 1/2+EE  over the range of about 15-60 L/min. The patient inhales the drug composition from the inhaler with an inspiration flow rate of about 15-60 L/min, resulting in a delivery efficiency measured by respirable fraction greater than 20%.
Patent DE-69734895-D1 (DE)
Inventor: TAKAHASHI MIGAKU
IPC: H01F10/16
Filed: 1997-03-28
Granted: 2006-01-19
Abstract: A magnetic recording medium having a high coercive force of a ferromagnetic metal layer, a high anisotropic magnetic field and/or normalized coercive force, and adaptable to high density recording. The magnetic recording medium comprises a substrate body and a ferromagnetic metal layer containing at least Co and Cr formed thereon via a metallic underlying layer of Cr. Magnetic inversion is utilized for the recording. A region (1) which penetrates through the ferromagnetic metal layer and in which Cr is segregated are formed among the crystal grains constituting the ferromagnetic metal layer. The Cr concentration in the intermediate portions of the region (1) in the direction of thickness of the ferromagnetic metal layer is smaller than that of the portions near the surface and near the metallic underlying layer. The crystal grains of the ferromagnetic metal layer are constituted by a region (2) in which the Cr concentration increases toward the grain boundary and a region (3) which is formed at the center of the crystalline particle and whose Cr concentration is lower than that near the grain boundary. The maximum Cr concentration in the region (3)b is smaller than the maximum Cr concentration in the region (2). <IMAGE>
Patent DE-69735157-D1 (DE)
Inventor: VENDRAMIN GIUSEPPE
IPC: H01L23/12
Filed: 1997-11-06
Granted: 2006-04-13
Abstract: A Plastic Ball Grid Array electronic package of the Cavity Down type for use in HF application. A Faraday Cage is realized to protect the active element from external HF wave interferences. The lateral sides of the Faraday Cage are constituted by a row of solder balls connected in a zig-zag way to plated through holes along the four edges of the substrate. The top side of the Cage is the metal stiffener of the Cavity Down package electrically connected to the through holes, while the bottom side is represented by the ground plane of the main board properly connected to the solder balls.
Patent DE-69740162-D1 (DE)
Inventor: BURCH DAVID GEORGE SIDNEY
IPC: A61K9/08
Filed: 1997-07-03
Granted: 2011-05-12
Abstract: Use of 14-O-[1-[(R)-2-amino -3-methylbutyrylamino] -2-methyl propan-2-yl thioacetyl]mutlin of formula (I), in free base or in veterinarily acceptable salt form, in the therapy of veterinary diseases, the expression of which is enhanced by increasing stocking density. Also claimed is a process for preparing a medicament for use in veterinary disease comprising (I) with a carrier or diluent.
Patent DE-69801431-D1 (DE)
Inventor: KUSTER KASPAR
IPC: F26B21/00
Filed: 1998-04-07
Granted: 2001-09-27
Abstract: An apparatus for the treatment of flat-form material, especially of coated printed circuit boards, wherein the printed circuit boards are subjected to various treatment processes in succession, such as airflow treatment, drying, and cooling, while they are being transported through a housing in which treatment processes are carried out, there are provided in the housing, for the purpose controlling of the process and increasing the adaptability of the treatment installation, individual treatment zones separate from one another, and the printed circuit boards are conveyed into the individual treatment zones in groups, a separate treatment process being carried out in each treatment zone.
Patent DE-69805032-D1 (DE)
Inventor: NAPPINI FRANCESCA
IPC: H02B13/025
Filed: 1998-07-20
Granted: 2002-05-29
Abstract: The present invention relates to a device for extinguishing the flame particularly in medium voltage electrical switchboards that features the distinctive characteristic of comprising, in the path for releasing the fumes produced by the occurrence of the arc inside an electrical switchboard, a body that is permeable to the passage of the fumes. The aforesaid body comprises a mass with low thermal inertia to absorb heat to extinguish the flame by cooling. <IMAGE>
Patent DE-69805106-D1 (DE)
Inventor: HEIL F
IPC: B65D19/44
Filed: 1998-12-23
Granted: 2002-05-29
Abstract: A pallet for a wheeled item (12) comprises a base frame (20) having openings (41) for receiving forklift arms, a plurality of tracks (22, 24) mounted on the base frame (20) for receiving the wheels (14) of the item (12), and a plurality of ramps (26, 28) mounted on the base frame (20) and sloping from the tracks (22, 24) toward the base frame (20) so that when the wheeled item (12) is shifted on the wheels (14) from the tracks (22, 24) along the ramps (26, 28), the undercarriage (118) of the wheeled item (12) comes to rest on the pallet. Wheeled items can be quickly loaded and secured on the pallet and can be manipulated with a forklift for storing wheeled items in stacked relation. The pallet can be designed to store wheeled items with aligned or offset casters.
Patent DE-69806955-D1 (DE)
Inventor: BONFIGLI GIUSEPPE
IPC: B61L5/00
Filed: 1998-10-19
Granted: 2002-09-05
Abstract: Switch box for railway, tramway, or similar comprising a drive unit (M, 3, 4, 5, 5', 5'', 5''', 6) for the shifting motion of the blades (A1, A1', A2, A2') and at least one group of linear transmission (12, 20, 21, 24) of the drive motion to the blades, movable device (24, 124) to lock the blades in their respective closed positions. The groups are housed in a box (1) which has substantially the dimensions and the shape of a sleeper and which is fitted in the track in place of and with the function of a sleeper. The switch box has movable device (23, 24, 124) to lock the blades (A1, A1', A2, A2') in their corresponding closed positions. The device (23, 24, 124) are associated with their respective blade (A1, A2) and arranged inside the box (1) in the area of the same and are brought automatically into active locking position when the corresponding blade (A1, A2') reached the closed position, while they are automatically disengaged on activation of the switch box to switch the blade into the position of closure of the blade (A2', A1) opposite.
Patent DE-69810578-D1 (DE)
Inventor: MIZUNO AKIRA
IPC: A61P9/00
Filed: 1998-03-16
Granted: 2003-02-13
Abstract: Disclosed are pyrroloazepine compounds and their salts. These pyrroloazepine compounds are represented by formula (I) wherein the dashed line indicates the presence or absence of a bond; and, when the bond is present, Z2 is not present and Z1 is H but, when the bond is absent, Z1 and Z2 are both Hs; Z1 is H and Z2 is OH; Z1 and Z2 are both SR5s in which R5 is alkyl, aralkyl or aryl; or Z1 and Z2 are combined together to represent O, NOR6 in which R6 is H, alkyl, aralkyl or aryl, or C2-C3 alkylenedithio; R is H, alkyl, cycloalkyl, cycloalkyl alkyl or aralkyl; and the ring P is a specific pyrrole ring. These pyrroloazepine compounds and salts are effective as preventives or therapeutics for general circulatory diseases such as hypertension, heart failure, ischemic hear diseases, cerebrovascular disturbances and peripheral circulatory disturbances. Their production processes are also disclosed
Patent DE-69813790-D1 (DE)
Inventor: CLAES JOSEPH
IPC: G05B9/03
Filed: 1998-07-29
Granted: 2003-05-28
Abstract: Sensors (SEN1,2,3) monitor, in parallel, a parameter from the same part of the process, producing input signals (E1,2,3) in digital form from the analogue to digital converter (EIN1,2,3). The signals are fed to individual programable logic controls (PLC) and memory units (MEM1,2,3) linked to programable test units (TES1,2,3). Output signals (S1,2,3) produce control signals (R1,2,3) which are compared in the comparator (SEC) producing an actuating signal (CL) based on majority voting i.e. comparing all control signals for variation in value and accepting two or three similar signals as the true value. The control signals actuate a regulator (REG) to activate control action in the process (e.g. valve opening or, in an emergency, process shut down). The test units are programable with the same control information as in the PLC's and produce an output signal in response to the same input signal (E). The two signals are compared in the memory units (MEM1,2,3) and, if different, generate alarm signals (AL1,2,3). The supervision unit (SUP) compares all inputs and decides on activation of an emergency alarm (EM) using similar voting system as described for the comparator (SEC). Network connections provide an overview of the system activity.
Patent DE-69819896-D1 (DE)
Inventor: MALCHESKY S
IPC: A61L2/18
Filed: 1998-06-23
Granted: 2003-12-24
Abstract: A decontamination apparatus for medical devices includes a decontamination basin (14a, 14b) with a selectively opened and closed cover member (16a, 16b) to provide selective access to the basin (14a, 14b). A mixing chamber assembly (80) selectively dispenses detergent concentrate and decontaminant concentrate into a liquid to form a liquid cleaning solution or a liquid decontaminant solution, respectively. A source of decontaminated rinse liquid, such as a microbe removal filter (54), is in selective fluid communication with the basin (14a, 14b). A source of anti-microbial liquid is in selective fluid communication with the microbe removal filter (54) and rinse liquid flow paths (58) between the microbe removal filter and the basin for decontaminating the filter (54) and the rinse lines (58). Each channel of a medical device (E) being decontaminated is connected to a channel flush line (30) and a channel pump (32) for flushing the channels of the device (E). A pressure sensor (42) is in communication with each flush line (30) to sense a blockage in the channels of the medical device (E). The channel pumps (32) pump liquid or decontaminated air through the device channels. A leak test system is also provided for testing the integrity of an outer sheath of a medical device (E) such as an endoscope.
Patent DE-69837283-D1 (DE)
Inventor: SCHROIT ALAN J
IPC: A61P35/00
Filed: 1998-12-31
Granted: 2007-04-19
Abstract: Disclosed are methods and compositions for the prevention and treatment of cancers using lipid-carrier protein conjugate compositions for generating lipid-specific immune responses in an animal. Also disclosed are methods for making phosphatidylserine conjugate compositions and their formulation for use in a variety of pharmaceutical applications including the detection and treatment of a variety of cancers and related conditions.
Patent DE-69839698-D1 (DE)
Inventor: CARDINA DONALD M
IPC: H04Q7/38
Filed: 1998-06-12
Granted: 2008-08-21
Abstract: Apparatus, method and system for notifying a communications switching center that a subsequent communication directed to a wireless number associated with the wireless unit is to be routed to a directory number associated with the wireless unit. A converter may be provided and connected to a current source and to a communications switching center. The wireless unit may be connected to the converter, and if connected, the unit draws current therefrom. In response to the draw of current by the wireless unit through the converter, the converter transmits a message to the communications switching center. The message includes a notification that a subsequent communication directed to the wireless number associated with the wireless unit is to be routed to the directory number associated with the wireless unit.
Patent DE-69840571-D1 (DE)
Inventor: CONTRERAS ALARCON ORESTES ROLANDO
IPC: C12Q1/10
Filed: 1998-04-20
Granted: 2009-04-02
Abstract: The present invention is related to the Microbiology, and form part of a system for the rapid microbiological diagnosis. The invention allows to detect turbidimetric changes due to microbial growth, using an equipment comprising two main devices: an static turbidimetric minireader and a microflow sensor which is fed by a peristaltic pump, being this equipment coupled to a microcomputer with a program package for acquisition, processing and creation of data bases to be used in generating necessary reports. The diagnostic kit has a glass vial with culture medium and containing a polymer with de-repressive activity and two additional substrates for E. coli identification, as well as a set of antibiotic discs organized in a strip for antibiogram determination from previously isolated colonies or samples obtained directly from their sources, allowing detection of infections of urinary tract from direct samples of urine, including simultaneous identification of E. coli. <IMAGE>