baber/WOPTO huggingface dataset:
Patent NZ-331256-A (NZ)
Title: Benzo[c]quinolizine derivatives, their preparation and use as 5 alpha-reductases inhibitors
Inventor: GUARNA ANTONIO
IPC: C07D455/03
Filed: 1997-02-07
Abstract: The present invention refers to benzo[c]quinolizine derivatives of general formula (I)their pharmaceutically acceptable salts or esters, processes for their preparation and pharmaceutical compositions containing them.
Patent NZ-333012-A (NZ)
Title: Open-cell expanded ceramic with a high level of strength, and process for the production thereof
Inventor: ADLER JORG
IPC: B01D39/20
Filed: 1997-05-30
Abstract: A high strength open-cell expanded ceramic that may be used for example in the form of a deep-bed filter, heat exchangers or the like, and a process for the production thereof.  Described is an open-cell expanded ceramic in which the inner cavities, cracks and the porosity of the ceramic members are filled partially or completely by one or a plurality of metal and/or ceramic phases and/or glass phases. During the manufacture of the ceramic, an open-cell polymer foam is cut to size and coated with a suspension of ceramic particles and water solvent, then pressed out and dried.  The polymer foam is then burned out or pyrolized, and during or after the following sintering phase, the cavities, cracks and the porosity of the ceramic members are partially or completely filled with a melt or a suspension which melts below the melting temperature of the expanded ceramic.
Patent NZ-336895-A (NZ)
Title: Heat resistant security document having an insulating material to prevent premature colour development when passing through heated printing devices.
Inventor: LAKES A DALE
IPC: B42D15/10
Filed: 1998-01-12
Abstract: A security document (10), which is resistant to premature colour development by heated printing devices, comprising a substrate (12) coated with a composition (14) of an initially colourless colour former, a colour developer and an insulating material (15). This is then further coated with a toner adhesion enhancing coating (16), which also preferably includes the insulating material (15). The security document (10) thus provides an authentication feature and/or an indication of attempted alterations from the use of solvent, heat or abrasives.
Patent NZ-510135-A (NZ)
Title: Trivet that can support either a flat bottom cooking vessel or a curved bottom cooking vessel, with at least three transverse supports
Inventor: BROWN SIMON
IPC: F24C15/10
Filed: 2001-02-23
Abstract: The trivet supports either a flat-bottomed pot (110) or a curved bottom wok (114) on at least three vertical supports (112). Typically this is achieved by inverting the trivet.
Patent NZ-516647-A (NZ)
Title: Sanitary ware and method for production thereof
Inventor: TOMIOKA YUTAKA
IPC: C04B41/89
Filed: 2000-06-16
Abstract: A sanitary ware wherein a first coloring glaze layer is formed on the surface of a ceramic body, a second transparent glaze layer is formed on the first glaze layer, and an engobe layer is formed between said body surface and said first glaze layer.
Patent NZ-517038-A (NZ)
Title: Use of serotonin reuptake inihibitor in medicaments for treating sexual dysfunction
Inventor: THOR KARL BRUCE
IPC: A61K31/138
Filed: 2000-08-22
Abstract: The use a therapeutically effective amount of a rapid-onset selective serotonin reuptake inhibitor on an as-needed basis shortly before sexual activity for the production of a medicament in the prevention, treatment, or management of sexual dysfunction, such as premature ejaculation, by administering to a patient in need of therapy.
Patent NZ-520093-A (NZ)
Title: Thienopyrimidine and thienopyridine derivatives useful as anticancer agents
Inventor: MUNCHHOF MICHAEL JOHN
IPC: A61P35/00
Filed: 1998-10-22
Abstract: A compound of formula 1 or 2, which may be used in a pharmaceutical composition for the treatment of benign hyperplasia of skin or prostate, or cancer. A compound of formula 1 or 2 may also be combined with an anti-tumour agent such as for example mitotic inhibitors, alkylating ganets, anti-metabolite and topoisomerase inhibitors, to form a pharmaceutical composition.
Patent NZ-521959-A (NZ)
Title: Guaifenesin sustained release formulation and tablets
Inventor: BLUME RALPH W
IPC: A61K47/38
Filed: 2001-04-26
Abstract: Sustained release composition capable of providing therapeutically effective bioavailability of guaifenesin for at least 12 hours comprising guaifenesin and a hydrophilic polymer and a water-insoluble polymer in the ratio 1:1 to 6:1. The formulation may comprise a hydrophilic polymer, preferably a hydroxypropyl methylcellulose, and a water-insoluble polymer, preferably an acrylic resin, in a ratio range of about one-to-one (1:1) to about six-to-one (6:1), more preferably a range of about three-to-two (3:2) to about four-to-one (4:1), and most preferably about two-to-one (2:1), by weight. This formulation is capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject. The invention also relates to a modified release guaifenesin tablet which has two portion: the first portion comprises an immediate release formulation of guaifenesin and the second portion comprises a sustained release formulation of guaifenesin as described above. This two portion or bi-layer tablet has a maximum serum concentration equivalent to that of an immediate release guaifenesin tablet, and is capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject.
Patent NZ-525732-A (NZ)
Title: Concrete formwork wall serving also as reinforcement
Inventor: MESSIQUA PIERRE
IPC: E04B2/84
Filed: 2001-01-10
Abstract: Disclosed is a wall made of concrete or the like produced from an unfolded formwork integrated in the wall and comprising two boxing panels (8, 8', 10) facing each other and connected by linking elements (1) articulated to the casing panels via stiffeners (2) integral with the casing panels. The space between the casing panels after they have been unfolded is filled with a filler material (7) such as concrete. At least one of the casing panels comprises an embedment made of concrete, mortar or the like, in added thickness relative to the stiffeners ( (2) and the articulated linking elements (1). The embedment (11, 12) is arranged outside and/or inside the casing panel, the stiffeners ( (2) and the articulated linking elements (1) and the casing panel (8) when it is embedded form an inner reinforcement of the wall encased in the wall and covered by the embedment. The use of separate stiffeners, which must be inserted before casting concrete, is thus avoided or highly reduced.
Patent NZ-527020-A (NZ)
Title: Gaming device and method
Inventor: STONE JAY
IPC: G07F17/34
Filed: 2002-01-10
Abstract: The gaming device (10) includes a housing (16), which supports a visual display (2), preferably a video monitor. The display (2) may include a window (8) for special messages of for incrementing counting of credits accumulated by the player. The window (8) can be used to describe the initiation of the feature of the gaming device (10) in which a player is awarded outright for a winning combination and is eligible for a reward if the displayed outcome can be manipulated by the gaming device (10) to produce a winning combination.
Patent NZ-527489-A (NZ)
Title: Tobacco casing steam treatment with predetermined moisture content and temperature range
Inventor: INTORP MICHAEL
IPC: A24B3/12
Filed: 2001-06-15
Abstract: Process for the treatment of tobacco, in particular of Burley tobacco, comprises the following steps:- (a) Treatment of tobacco, preferably leaf tobacco, with a casing which preferably contains sugar; and (b) Thermal treatment of the casing- treated tobacco with saturated steam, wherein, before the steam treatment, the moisture content of the tobacco is in the range from 15 % to 25 % and after the treatment the moisture content is in the range from 15 % to 25 % and the tobacco temperature is in the range from 80 to 115 degrees Celsius.
Patent NZ-528141-A (NZ)
Title: Metalloproteinase inhibitors
Inventor: LEPISTO MATTI
IPC: C07D403/12
Filed: 2002-03-13
Abstract: Compounds of the formula (I) that are useful as metalloproteinase inhibitors, especially as inhibitors of MMP12 are disclosed, wherein X is NR1, O or S; Y1 and Y2 are independently selected from O and S; Z is NR2, O or S; m is 0 or 1; R5 is a bicyclic or tricyclic group as defined in the specification; and wherein R1, R2, R3, R4, R6 and A are as defined in the specification.
Patent NZ-531618-A (NZ)
Title: A bio-security system
Inventor: MCHARDY NICHOLAS
IPC: A61D7/00
Filed: 2002-09-10
Abstract: A method for preventing contamination of a teat during administration of a sealant comprises the steps of introducing/delivering a sterilising agent into the teat and subsequently delivering the sealant into the teat. A sealant injector (1) has a nozzle (3) with a removable protective cap (2). A sterilising agent (4) such as a bacteriocin is provided between the nozzle (3) and the contents of the sealant injector (1).
Patent NZ-533738-A (NZ)
Title: Synthetic peptides and uses thereof for the prevention and therapy of cancer invasion and metastasis
Inventor: RATH MATTHIAS
IPC: A61K9/02
Filed: 2003-01-23
Abstract: An oligopeptide comprises SEQ ID No: 2 or 6 corresponding to amino acids 85-92 of MMP-2 can be used for the preparation of a pharmaceutical composition for the prevention or the treatment of cancer, infectious diseases, cardiovascular diseases, degenerative diseases, or pathological conditions associated with the destruction of the extracellular matrix by MMPs.
Patent NZ-538996-A (NZ)
Title: Methods and compositions for increasing antibody production
Inventor: REILLY DOROTHEA
IPC: C07K16/42
Filed: 2003-10-30
Abstract: Disclosed are methods and compositions for improved expression and production of recombinant antibodies in host cell expression systems. In particular, prokaryote expression and production of antibodies with modified hinge cystine residues are provided. Further disclosed are compositions, kits and articles of manufacture for practicing the methods disclosed herein.
Patent NZ-540206-A (NZ)
Title: Multiple variants of meningococcal protein NMB1870
Inventor: COMANDUCCI MAURIZIO
IPC: A61K39/095
Filed: 2003-11-21
Abstract: A composition comprising at least two of the following antigens: (a) a first protein, comprising an amino acid sequence having at least 85% sequence identity to SEQ ID NO:24; (b) a second protein, comprising an amino acid sequence having at least 85% sequence identity to SEQ ID NO:33; and (c) a third protein, comprising an amino acid sequence having at least 85% sequence identity to SEQ ID NO:41. A mixture of two or more of (a), (b) and (c) can elicit an antibody response which is bactericidal against particular N. meningitidis strains.
Patent NZ-540728-A (NZ)
Title: Compositions and methods for combination antiviral therapy
Inventor: DAHL TERRENCE C
IPC: A61K31/675
Filed: 2004-01-13
Abstract: Disclosed is the use of [2-(6-amino-purin-9-yl)-1-methyl-ethoxymethyl}-phosphonic acid diisopropoxycarbonyloxymethyl ester fumarate (tenofovir disoproxil fumarate) and (2R, 5S, cis)-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one (emtricitabine) in the manufacture of a medicament for the treatment of a patient in need of antiviral therapy consisting of anti-HIV therapy, wherein the medicament is a tablet.
Patent NZ-543911-A (NZ)
Title: Sheet of construction material with marked lines associated with reference scales of a saw guide
Inventor: HARRIS DAVID N
Filed: 2003-06-11
Abstract: A sheet of construction material with marked lines for guiding a cutting tool is disclosed. The sheet material 100 has a number of fiducial lines 112 marked on its upper surface. A guide 216 mounted on a cutting tool 200, such as a circular saw, has a set of alignment marks 220 and at least three measurement scales 222. Each measurement scale corresponds to at least one of the fiducial lines so that when one of the alignment marks is aligned with a fiducial line the corresponding scale indicates the distance from the blade to an edge of the sheet material.
Patent NZ-544952-A (NZ)
Title: Gene expression profiles that identify genetically elite ungulate mammals
Inventor: LEWIN HARRIS A
IPC: G06F19/00
Filed: 2004-05-27
Abstract: Provided is a method of determining whether a cow is genetically elite for a milk production level of interest, the method comprising: (a) determining a gene expression profile for a plurality of genes selected from group of 25 specified sequences for milk production for cattle; (b) comparing the gene expression profile with the Gene Expression Index of cows with known milk production of claim 1 for the milk production level of interest; and (c) designating the cow as elite if the gene expression profile is statistically correlated with the Gene Expression Index of cows with known milk production. Further provided are corresponding microarrays and assay kits and methods of predicting milk production in a candidate cow.
Patent NZ-549084-A (NZ)
Title: Live attenuated salmonella for use as vaccine
Inventor: MIZUNO TETSUO
IPC: A61K39/112
Filed: 2005-02-14
Abstract: Disclosed is a therapeutic agent comprising a live attenuated microorganism of the family Enterobacteriaceae produced by selecting from metabolic drift mutants of a wild strain of a microorganism of the family Enterobacteriaceae an attenuated microorganism that has a reduced capacity to grow and replicate in the presence of bile salts as compared to the wild strain, wherein the attenuated microorganism is capable of inducing an immune response in the subject to the wild strain.
Patent NZ-551159-A (NZ)
Title: Pulley holder with strap loop ends within acute angle forks of housing
Inventor: BORISSENKO VLADIMIR IVANOVICH
Filed: 2006-11-09
Abstract: Strap 3 with high friction lining 4 is in use located about a pulley (not shown), and its ends are connected to a slider mechanism. Handle 2 is provided to hold the device and typically it is rotated to move the slider mechanism thereby tightening or loosening strap 3.
Patent NZ-564706-A (NZ)
Title: Trend monitoring system with multiple access levels
Inventor: TICE LEE
IPC: A61B5/00
Filed: 2006-06-23
Abstract: A system for monitoring trends in a physiological condition comprises at least one in-home sensor of a physiological parameter of a person and control circuitry and executable software local to the sensor. The control circuitry receives information from the at least one sensor and the software evaluates the information relative to at least one baseline. The system also comprises multi-level access control software, local to and coupled to the control circuitry. The multi-level access control software provides access to medical and personal information of the person at a predetermined level in response to a locally entered password. The predetermined level of accessible information is selected from a plurality of stored levels of medical and personal information. The multi-level access control software has an access level for caregivers based upon entry of a first password by the caregiver and another access level for a physician based upon entry of a second password by the physician. The system further comprises an input device, local to and coupled to the control circuitry and an output device, local to and coupled to the control circuitry. The input device enables the person to manually enter condition related information; and, the control circuitry visually presents substantially real-time trend information to the person.
Patent NZ-569503-A (NZ)
Title: Improved targeted nucleotide exchange with propynyl modified oligonucleotides
Inventor: BUNDOCK PAUL
IPC: A61K31/7088
Filed: 2006-12-20
Abstract: A method for targeted alteration of a duplex acceptor DNA sequence. The method comprises combining the duplex acceptor DNA sequence with a donor oligonucleotide in the presence of proteins that are capable of targeted nucleotide exchange. The donor oligonucleotide comprises at least two modified nucleotide selected from C7-propyne purine and a C5-propyne pyrimidine and at least one nucleotide mismatch with respect to the duplex acceptor DNA sequence to be altered. The propynyl modified nucleotides bind stronger to a nucleotide in an opposite position compared to a naturally occurring nucleotide.
Patent NZ-571203-A (NZ)
Title: Monocyclic heteroaryl-phenyl-cyclohexyl compounds for treating diseases mediated by DGAT-1 activity
Inventor: SERRANO-WU MICHAEL H
IPC: C07D213/75
Filed: 2007-03-28
Abstract: Disclosed are monocyclic heteroaryl-phenyl-cyclohexyl compounds represented by general formula (I). Also disclosed is the use of the compounds of formula (I) for treating a condition associated with DGAT1 activity such as: i) a metabolic disorder selected from the group consisting of obesity, diabetes, anorexia nervosa, bulimia, cachexia, syndrome X, insulin resistance, hypoglycemia, hyperglycemia, hyperuricemia, hyperinsulinemia, hypercholesterolemia, hyperlipidemia, dyslipidemia, mixed dyslipidemia, hypertriglyceridemia, and non-alcoholic fatty liver disease; ii) cardiovascular disease selected from the group consisting of atherosclerosis, arteriosclerosis, acute heart failure, congestive heart failure, coronary artery disease, cardiomyopathy, myocardial infarction, angina pectoris, hypertension, hypotension, stroke, ischemia, ischemic reperfusion injury, aneurysm, restenosis, and vascular stenosis; iii) neoplastic disease selected from the group consisting of solid tumors, skin cancer, melanoma, lymphoma, endothelial cancers including breast cancer, lung cancer, colorectal cancer, stomach cancer, cancers of the gastrointestinal tract including esophageal cancer and pancreatic cancer, prostate cancer, kidney cancer, liver cancer, bladder cancer, cervical cancer, uterine cancer, testicular cancer, and ovarian cancer. iv) a dermatological condition; and v) as an anorectic.
Patent NZ-572548-A (NZ)
Title: Stabilized insulin-like growth factor polypeptides
Inventor: GLASS DAVID JONATHAN
IPC: A61K38/30
Filed: 2007-06-06
Abstract: Disclosed is a polypeptide comprising a human IGF-1 precursor protein, wherein: (i) one or more of the following precursor protein residues is deleted or mutated: G1, P2, E3, R36 and R37; and (ii) the cleavage of the E-peptide from IGF-1 by a protease is reduced by modification of the precursor protein. Also disclosed is the use of the said polypeptides in the manufacture of medicaments for the treatment of a musculoskeletal disease, diabetes, neuronal cell death, or anemia.
Patent NZ-577644-A (NZ)
Title: Storage device with pouch for power dependent device and/or cord parts, and outer flange parts distanced by stand-offs forming a hub
Inventor: QUINN PAUL MICHAEL SHANE
IPC: H02G11/02
Filed: 2010-06-11
Abstract: A cable storage device 1 has a pouch 5 for receiving at least one of: cord; termination part of cord; or power dependent device. Outer flange portions 4 are distanced from the pouch 5 by stand-offs forming a composite hub so as to form a channel 3 about which a cord can be wrapped.
Patent NZ-579793-A (NZ)
Title: Laser activated micro accelerator platform
Inventor: TRAVISH GIL
IPC: H05H15/00
Filed: 2008-04-04
Abstract: A micro-accelerator platform (MAP) comprises an electron source (22); a first dielectric slab (16); a second dielectric slab (18) and, a source of optical radiation (via 14). The first dielectric slab has a reflective surface having a plurality of slots and an active surface. The second dielectric slab has a reflective surface having a plurality of slots and an active surface. This active surface is oriented opposite the active surface of the first dielectric slab forming a gap (20) between the active surfaces. The source of optical radiation is configured to direct beams of light on the reflective surfaces of the first and second dielectric slabs. The electrons emitted from the electron source are accelerated within the gap between the active surfaces of the first and second dielectric slabs. Also disclosed is another micro-accelerator platform, comprising an electron source; a first dielectric slab with a reflective surface having a plurality of slots and an active surface; a second dielectric slab with an active surface with the active surface oriented opposite the active surface of the first dielectric slab forming a gap between the active surfaces; a reflector operably coupled to the second dielectric slab parallel to the active surface of the slab; and a source of optical radiation configured to direct beams of light on the reflective surface of the first dielectric slab. The electrons emitted from the electron source are accelerated within the gap between the active surfaces of the first and second dielectric slabs. A radiation source (10) comprises an evacuated housing (12); and the above described micro-accelerator platform assembly disposed within the evacuated housing.
Patent NZ-583969-A (NZ)
Title: Mixed metal compounds for treatment of hyperphos phataemia
Inventor: NEWTON MAURICE SYDNEY
IPC: A61K33/244
Filed: 2008-10-15
Abstract: Disclosed are mixed metal compounds of formula (III) MIl1-aMIIla(OH)dAn-c.ZH20 (III) wherein MIl is at least Mg (II); MIll is at least one trivalent metal selected from AI(III), Mn(III), Fe(III), La(III) and Ce(III); An- is at least one n-valent anion and wherein at least one anion is carbonate; 1>a>0.7; Wherein the mixed metal compound comprises less than 15 percent water soluble salts by weight of the mixed metal compound after drying. Also disclosed are pharmaceutical compositions comprising the mixed metal compounds as well as the use of the mixed metal compounds for binding phosphate and for treating hyperphosphataemia, metabolic bone disease, metabolic syndrome, renal insufficiency, hypoparathyroidism, pseudohypoparathyroidism, acute untreated acromegaly, chronic kidney disease (CKD), severe bone problems, soft tissue calcification, secondary hyperparathyroidism, over medication of phosphate salts and other conditions requiring control of phosphate absorption.
Patent NZ-584138-A (NZ)
Title: 2-anilinopurin-8-ones as inhibitors of ttk/mps1 for the treatment of proliferative disorders
Inventor: ANDREWS DAVID MICHAEL
IPC: A61K31/52
Filed: 2008-08-20
Abstract: A compound of formula (I) wherein R1-R4, m and n are defined in claim 1. The compound is used for the treatment of cancer and to produce a Tyrosine Threonine Kinase (TTK)/monopolar spindle 1 (Mps1) inhibitory effect.
Patent NZ-584294-A (NZ)
Title: Fastener driving tool using a gas spring
Inventor: PETROCELLI MICHAEL V
IPC: B25C1/06
Filed: 2008-10-01
Abstract: A portable linear fastener driving tool is provided that drive staples, nails, or other linearly driven fasteners. The tool uses a gas spring principle, in which a cylinder filled with compressed gas is used to quickly force a piston through a driving stroke movement, while a driver also drives a fastener into a workpiece. The piston/driver is then moved back to its starting position by use of a rotary-to-linear lifter, and the piston again compresses the gas above the piston, thereby preparing the tool for another driving stroke. The driver has protrusions along its edges that contact the lifter, which lifts the driver during a return stroke. A pivotable latch is controlled to move into either an interfering position or a non-interfering position with respect to the driver protrusions, and acts as a safety device, by preventing the driver from making a full driving stroke at an improper time.