baber/WOPTO huggingface dataset:
Patent CA-2400174-A1 (CA)
Title: Resonateur raman en cascade a germination de profil de gain
Inventor: GILTNER DAVID M
IPC: H01S3/23
Filed: 2001-02-23
Abstract: L'invention concerne une source de signaux pourvue d'un dispositif du type résonateur Raman en cascade doté d'un signal de germes servant à réguler la sortie spectrale de la source. Plusieurs instructions de Stokes sont produites dans un milieu à gain, l'instruction de Stokes la plus élevée étant autorisée à sortir. Le signal de germes est fourni au milieu à gain par une source de germes, et se situe dans la gamme de longueur d'onde de l'instruction de Stokes la plus élevée. Le signal de germes stimule le gain décalé Raman dans la gamme de longueur d'onde dudit signal, ce qui permet de réguler la gamme de longueur d'onde de sortie du milieu à gain. Dans un mode de réalisation, le signal de germes est un signal à bande large qui produit une sortie à bande large à partir du milieu à gain. Dans un autre mode de réalisation, le signal de germes est produit par un certain nombre de sources à bande étroite couplées avant introduction au milieu à gain. La source de germes peut être réglée de façon à ajuster la distribution spectrale énergétique de la sortie à partir de la source de signaux. L'ajustement peut se faire en combinaison avec la surveillance active des signaux de la sortie de la source de signaux. On peut également utiliser la source de signaux pour pomper un milieu à gain dans lequel un signal voulu est amplifié, la distribution spectrale énergétique de ce signal pouvant être surveillée aux fins des ajustements de la source de germes.
Patent CA-2402686-A1 (CA)
Inventor: TUCKER GORDON
IPC: C07D471/04
Filed: 2001-03-06
Abstract: L'invention concerne de nouveaux composés répondant à la formule (I) :       dans laquelle G représente un groupement phényle; G1 et G2 représentent un atome de carbone;   T1 représente un groupement -CH2-CH2-, -CH=CH- ou =CH-CH2-, et -T2- représente une liaison, R5 représente un groupement -(CH2)m-COOR6 dans lequel m est un entier compris entre 1 et 6 inclusivement; R6 représentent un atome d'hydrogène ou un groupement alkyle, aryle ou arylalkyle; W représente un groupement -CH-, =C- ou -C= et A  représente un groupement -CH2- ou =CH-; X représente un groupement choisi parmi -CO-X1-, -CO-X1-, -NR6-CO-X1-, -O-X1-, -SO2-NR6-X1- et -S(O)n-X1-, dans lesquels n est compris entre 0 et 2 inclusivement, et X1 représente un groupement alkylène; Y représente un groupement choisi parmi -Y1-, -Y2-Y1- et -Y1-Y2-Y1-, dans lesquels Y1 représente un groupement alkylène, alkénylène ou alkynylène, et Y2 représente un groupement arylène, hétéroarylène, cycloalkylène ou hétérocycloalkylène; Z représente un groupement choisi parmi Z1-, Z10-NR6- et Z10-NR6-CO-, dans lesquels Z10 représente un groupement alkyle ou Z1, et Z1 représente un groupement choisi parmi Z2, Z2O-(C=NR6)-, Z20-NR6- et CO-, dans lesquels Z20 représente un groupement alkyle, hétéroalkyle ou Z2, et représente un groupement hétéroaryle, hétérocycloalkyle, hétéroarylalkyle, hétérocycloalkylalkyle, arylhétéroaryle fusionné, arylhétérocycloalkyle fusionné, hétéroarylhétérocycloalkyle fusionné, hétérocycloalkyl-hétéroaryle fusionné, hétéroarylhétéroaryle fusionné ou cycloalkylhétérocycloalkyle fusionné.  L'invention vise également les énantiomères et diastéréoisomères des composés de formule (I), ainsi que leurs sels d'addition à un acide ou à une base pharmaceutiquement acceptable.  Les composés selon l'invention sont utiles à titre de médicaments pour le traitement des maladies cardiovasculaires, des maladies inflammatoires, du cancer, de l'ostéoporose, de l'arthrite rhumatoïde, du psoriasis, des rétinopathies et des cancers.
Patent CA-2405365-A1 (CA)
Title: Suspension device
Inventor: SEEGERT BRIAN DAVID
IPC: A01D34/64
Filed: 2002-09-26
Abstract: A device for suspending a mower cutting deck that includes a retention member connected with the frame of a vehicle. The retention member receives a linkage bridging the cutting deck and the frame. To receive this linkage, the retention member includes a channel having a top end through which the linkage is inserted and a bottom end in which the linkage seats when the deck and the frame are connected. A throat portion is provided between the top and bottom ends.  The throat portion is laterally offset from the ends and provides an abutment which opposes inadvertent vertical movement of the linkage beyond the bottom end to substantially prevent it from moving out of the retention member. With this opposition, the deck can maintain its attachment with the frame of the vehicle while using a minimal amount of hardware.
Patent CA-2409515-A1 (CA)
Inventor: PEASE LARRY R
IPC: A61K35/12
Filed: 2000-05-30
Abstract: Methods are described for treating demyelinating diseases in mammals, such as multiple sclerosis in humans, and viral diseases of the central nervous system of humans and domestic animals, such as post-infectious encephalomyelitis, or prophylactically inhibiting the initiation or progression of demyelination in these disease states, using human monoclonal autoantibodies characterized by their ability to bind structures and cells within the central nervous system.  In particular, the methods utilize human monoclonal antibodies selected from the group of sHIgM22 (LIM 22), sHIgM46 ebvHIgM MSI19D10, CB2bG8, AKJR4, CB2iE12, CB2iE7 and MSI 19E5, monomers thereof, active fragments thereof and isolated or synthetic human or humanized autoantibodies having the characteristics of the foregoing. Nucleic acids and DNA molecules encoding the human monoclonal antibodies, or portions thereof, are provided. The invention also extends to the preparation and use of human polyclonal and monoclonal autoantibodies, monomers thereof, active fragments, peptide derivatives and fragments, and analogs, cognates, agonists and the like corresponding materials, and their use in diagnostic and therapeutic applications. For example, the autoantibodies, monomers, fragments, haptens, and peptide equivalents, are useful in the promotion of neural regeneration and neuroprotection, and therapeutic compositions and vaccines containing peptides or antibodies are included and presented.
Patent CA-2414287-A1 (CA)
Title: System and method for implementing local base stations
Inventor: MOUSSEAU GARY P
IPC: H04L12/28
Filed: 2001-06-27
Abstract: A system and method for implementing local base stations is provided. The system includes a plurality of mobile devices (20), a local area network (LAN) (14) , and a plurality of local base stations (44,46) coupled to the LAN. Each local base station in the system has a unique address on the LAN, and is configured to transmit and receive data packets to and from the mobile devices. Using the unique address assigned to a particular local base station, the data packets may be transferred between local base stations over the LAN.  Each local base station in the system may include a central processing unit (CPU) coupled to a sound card and a network interface card, and a transmitting and receiving means that sends and receives modulated RF signals to and from the mobile devices. The sound card is configured to demodulate an incoming RF  signal to produce an incoming frame of data, and to generate an outgoing modulated RF signal from an outgoing frame of data. Each local base station may also include a software module executed by the CPU and configured to extract a packet of data from the incoming RF signal and encode the packet of data into an outgoing datagram that includes addressing information enabling the outgoing datagram to be directed to another local base station over the LAN, and also configured to extract a data packet from an incoming datagram received from the LAN and encode the data packet into the outgoing frame of data tha includes information enabling the outgoing frame of data to be transmitted to the mobile device.
Patent CA-2415713-A1 (CA)
Title: Methods and compositions for rapid protein and peptide extraction and isolation using a lysis matrix
Inventor: CLAUSEN PETER
IPC: C12N1/06
Filed: 2001-07-13
Abstract: The present invention relates generally to compositions, methods and kits for use in extracting and isolating protein or peptide molecules. More specifically, the invention relates to such compositions, methods and kits that are useful in the isolation of protein or peptide molecules from cells (e.g., bacterial cells, animal cells, fungal cells, viruses, yeast cells or plant cells) via lysis and one or more additional isolation procedures, such as one or more filtration and/or chromatography procedures. In particular, the invention relates to compositions, methods and kits wherein protein or peptide molecules are isolated using an integrated lysis/filtration matrix, which may comprise one or more supports (e.g., polyolefin, scintered polyethylene, nitrocellulose, polypropylene, polycarbonate, cellulose acetate, silica, and the like). The compositions, methods and kits of the invention are suitable for isolating a variety of forms of protein or peptide molecules from cells.  The compositions, methods and kits of the invention are particularly well-suited for rapid isolation of recombinant protein or peptide molecules expressed in bacterial cells, either as soluble protein, or as an inclusion body. The invention is particularly useful in high throughput applications, allowing quick isolation and/or analysis of proteins and/or peptides from numerous sources.
Patent CA-2416814-A1 (CA)
Title: Locking fastener
Inventor: YAMADA FUSAO
IPC: F16B39/12
Filed: 2002-06-19
Abstract: In a fastener comprising a bolt (3), a nut (2), and a washer (1), a bolt through-hole (5) which is slightly larger than a nominal diameter of the bolt (3) is formed in a base portion (4) of the washer (1), a conical barrel member (6) whose diameter decreases toward an upward position in a bolt axial direction is formed around the bolt through-hole (5) so as to stand therefrom, a continuous slit for a notched circle is formed in the base portion (4) and the conical barrel member (6), the diameter of the conical barrel member (6) of such a washer (1) is decreased by the fastening of the nut (2) and the bolt (3), and the conical barrel member (6) is fitted into a conical hole portion (10) of the nut (2), thereby obtaining a state where the conical barrel member (6) of the washer (1) is bitten and sandwiched between the bolt (3) and the nut (2). The bolt (3) and the nut (2) are strongly integrated via two kinds of integration routes in the bolt axis orthogonal direction and the bolt axial direction, thereby rationally realizing a large locking effect.
Patent CA-2417347-A1 (CA)
Inventor: BLANK WERNER J
IPC: C08L23/26
Filed: 2001-08-02
Abstract: La présente invention concerne une composition polymérique réticulable contenant une polyoléfine fonctionnelle alcoxysilane et un catalyseur de réticulation silanol sélectionné dans le groupe constitué par : (i) un acide monosulfonique naphthalène alkylé substitué par des groupes 1-4 alkyles, où chaque groupe alkyle est un alkyle linéaire ou ramifié à 5-20 atomes de carbone et chaque groupe alkyle est identique ou différent, où le nombre total d'atomes de carbone dans les groupes alkyles est compris entre 20 et 80 atomes de carbone ; (ii) un acide sulfonique arylalkyle, où aryle est phényle ou naphthyle et est substitué par des groupes 1-4 alkyles, où chaque groupe alkyle est un alkyle linéaire ou ramifié à 5-20 atomes de carbone et chaque groupe alkyle est identique ou différent, et où le nombre total d'atomes de carbone dans les groupes alkyles est compris entre 12 et 80 ; (iii) un dérivé de (i) ou (ii) sélectionné dans le groupe constitué par un anhydride, un ester, un acétylate, un ester séquencé de résine époxyde et un sel amide dudit ester hydrolysable par rapport à l'acide monosulfonique naphthalène alkyle correspondant ou l'acide sulfonique arylalkyle ; (iv) un sel métallique de (i) ou (ii), dans lequel l'ion métallique est sélectionné dans le groupe constitué par cuivre, aluminium, étain et zinc. Ladite invention concerne également un procédé permettant de réticuler une polyoléfine fonctionnelle alcoxysilane au moyen d'un catalyseur décrit ci-dessus.
Patent CA-2417982-A1 (CA)
Inventor: LI DEAN Y
IPC: A61K35/44
Filed: 2001-08-03
Abstract: Methods and compositions for manipulating the arterial-venous identity of endothelial cells are provided. The methods comprise introducing an arterial molecular program into endothelial cells of a vein section such that the endothelial cells can remodel to form arterial endothelial cells. The arterial molecular program can comprise one or more polynucleotides encoding various genes that are associated with arterial development and/or differentiation from veins. Expression vectors comprising the genes can be used to introduce the molecular program into the cells. A method of treating a patient having an obstructed blood vessel is also provided.
Patent CA-2419036-A1 (CA)
Title: Non-imidazole aryloxypiperidines as h3 receptor ligands
Inventor: XIAO WEI
IPC: A61K31/55
Filed: 2001-08-06
Abstract: Substituted non-imidazole aryloxypiperidine compounds, compositions containing them, and methods of making and using them to treat or prevent histamine-mediated conditions.
Patent CA-2421654-A1 (CA)
Inventor: TSENG CHUEN-JONG
IPC: A47B3/10
Filed: 2003-03-11
Abstract: A table and bench assembly includes a table top unit, two bench units on opposite lateral sides, and front and rear leg units. Each leg unit has an inner leg portion pivoted to the table top unit, and two outer leg portions.    Each outer leg portion has an upper end provided with a slide seat mounted pivotally and slidably on one of the bench units. The slide seats slide along the bench units when the front and rear leg units are moved pivotally toward the table top unit and the bench units, thereby folding the table and bench assembly.
Patent CA-2422020-A1 (CA)
Title: Indicating light
Inventor: LUX KARL-HEINZ
IPC: F21Y115/10
Filed: 2003-03-13
Abstract: An indicating light for an optical display is disclosed and comprises a housing, a light-emitting diode and an electrical switch. The housing has electrical conductor parts. The diode is in a push element which has a translucent round head, a hollow rod with a first end area on which the push element is axially moveably located and wherein a second end area of the hollow rod is arranged in the housing. The switch is arranged in the hollow rod, in its longitudinal direction behind the light-emitting diode, and is operable by axial movement of the push element. A contact element disposed behind the light-emitting diode can be moved against a tappet of the switch and is arranged between the push element and the electrical switch.
Patent CA-2423038-A1 (CA)
Inventor: FERKO BORIS
IPC: A61K39/145
Filed: 2001-09-25
Abstract: L'invention concerne un procédé simple et efficace pour isoler des virus à partir de sources variées et pour produire des vaccins antigrippaux vivants atténués dans une culture cellulaire Vero sans sérum dans des conditions permettant de minimiser ou de prévenir une altération des antigènes de surface du virus due à une sélection adaptative. Ce procédé ne nécessite pas de purification du surnageant contenant le virus, obtenu à partir de la culture cellulaire, ni de traitement de post-incubation des virus pour activation HA. L'invention concerne également des souches mères de grippes A et B candidates, ainsi que des vaccins produits à partir de ces souches.
Patent CA-2426374-A1 (CA)
Title: Method for hydrocracking petroleum heavy oil
Inventor: YASUMURO MOTOHARU
IPC: B01J27/02
Filed: 2003-04-23
Abstract: Disclosed is a method for hydrocracking a petroleum heavy oil that is used to obtain a high distillate yield economically in hydrocracking a petroleum heavy oil containing heavy metals such as a vacuum residue. Specifically, the method comprises a reaction step of supplying a raw material slurry containing a petroleum heavy oil and a limonite ore catalyst, and a hydrogen gas to a suspended-bed reactor; and a step of hydrocracking the heavy oil under the reaction conditions of reaction pressure: 30 to 160 kg/cm2, reaction temperature: 430 to 455 °C, and reaction time: 30 to 180 minutes, wherein pretreating in which the raw material slurry is heated at a temperature of 320 to 420 °C for 10 to 60 minutes is performed during heating of the raw material slurry up to the reaction temperature: 430 to 455 °C.
Patent CA-2428069-A1 (CA)
Title: Compositions and methods for mitigating corrosion of applied color designs
Inventor: STEINDORF RICK EUGENE
IPC: C11D3/20
Filed: 2001-11-07
Abstract: The present invention relates to compositions and methods for mitigating corrosion of applied color designs on a bottle, or on another glass or ceramic item. More specifically the composition or method of the present invention can mitigate corrosion even in the presence of a known corrosive agent. The composition and methods of the invention employ one or more phosphates and one or more phosphonates at a ratio that reduces or minimizes corrosion of an applied color design.
Patent CA-2430851-A1 (CA)
Inventor: WILLIAMS CLARK CURTIS
IPC: C08F210/16
Filed: 2001-12-05
Abstract: L'invention concerne un procédé, conduit en phase gazeuse, qui consiste à mettre en contact une ou plusieurs oléfines avec un système catalytique renfermant un gaz vecteur et un mélange de matières solides, dans lequel on trouve un composé ou un complexe à base de métal de transition et un solvant organique liquide, en conditions de polymérisation, à l'intérieur d'un réacteur à lit fluidisé qui contient des particules de résine à l'état fluidisé, pour autant (a) que le mélange de matières solides et de solvant renferme au moins 95 %, en poids, de matières solides, et (b) que le mélange soit pulvérisé avec le gaz vecteur dans une zone à faible teneur en particules, ou le lit fluidisé, du réacteur.
Patent CA-2431294-A1 (CA)
Title: Chip de casino
Inventor: BROWN DARRELL L
IPC: A63F3/00
Filed: 2001-11-26
Abstract: La présente invention concerne un jeton de casino (22) de valeur attribuée possédant une partie transparente centrale (18) contenant au moins une particule distincte (19, telle qu'un élément métallique précieux ou semi-précieux. Lorsque le joueur le secoue, le jeton reproduit le son de crécelle d'une paire de dé.
Patent CA-2431518-A1 (CA)
Title: Resolving document object collisions
Inventor: GRIFFIN JOHN D
IPC: G06F17/24
Filed: 2003-06-09
Abstract: Collisions between document objects on a document page are resolved. collision is identified and a two-dimension resolution of the collision is provided by moving the object the shortest distance from a pre-collision location that would avoid the collision. The process calculates the shortest distance to move the object.  The invention also may establish logic that designates some objects as "not able to collide"  and the process will not move those objects to resolve a collision.
Patent CA-2432339-A1 (CA)
Inventor: HUSTERT ELISABETH
IPC: C12Q1/68
Filed: 2001-12-21
Abstract: L'invention concerne un polynucléotide polymorphe CYP3A5. Elle concerne aussi des gènes ou des vecteurs comprenant les polynucléotides de l'invention et une cellule hôte génétiquement modifiée au moyen du polynucléotide ou du gène de l'invention. Elle concerne encore des procédés de production des polypeptides de variant moléculaire ou des fragments de ceux-ci, de procédés de production de cellules capables d'exprimer un polypeptide de variant moléculaire et un polypeptide ou un de ses fragments codé par le polynucléotide ou le gène de l'invention ou que l'on peut obtenir au moyen du procédé ou des cellules produites par le procédé de l'invention. Elle concerne encore un anticorps qui se lie spécifiquement au polypeptide de l'invention. Elle concerne, en outre, un animal non humain transgénique. Elle concerne aussi un support solide comprenant un ou plusieurs des polynucléotides, gènes, vecteurs, polypeptides, anticorps et cellules hôtes mentionnés. Elle concerne encore des procédés d'identification d'un polymorphisme, d'identification et d'obtention d'un promédicament ou d'un médicament ou d'un inhibiteur. Elle concerne, en outre, des procédés de production de composition pharmaceutique, des procédés de diagnostic d'une maladie, un procédé de détection du polynucléotide de l'invention, un diagnostic et une composition pharmaceutique. Elle concerne encore l'utilisation des polynucléotides, gènes, vecteurs, polypeptides ou anticorps de l'invention. Elle concerne enfin un nécessaire de diagnostic.
Patent CA-2432642-A1 (CA)
Title: Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use
Inventor: FANG XINQIN
IPC: A61P29/00
Filed: 2001-12-21
Abstract: The invention describe novel substituted aryl compounds that are cyclooxygenase 2 (COX-2) selective inhibitors and novel compositions comprising at elast one cyclooxygenase 2 (COX-2) selective inhibitor, and, optionally, at least one compound that donates, transfers or releases nitric  oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase, and/or, optionally, at least one therapeutic agent, such as,  steroids, nonsterodal antiinflammatory compounds (NSAID), 5-lipoxygenase (5- LO) inhibitors, leukotriene B4 (LTB4) receptor antagonists, leukotriene A4 (LTA4) hydrolase inhibitors, 5-HT agonists, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) inhibitors, H2 antagonists, antineoplastic agents, antiplatelet agents,thrombin inhibitors, thromboxane inhibitors, decongestants, diuretics, sedating or non-sedating anti-histamines, inducibl e nitric oxide synthase inhibitors, opioids, analgesics, Helicobacter pylori inhibitors, proton pump inhibitors, isoprostane inhibitors, and mixtures thereof. The invention also provides novel kits comprising at least one COX- 2 selective inhibitor, and, optionally, at least one nitric oxide donor, and/o r, optionally, at least one therapeutic agent. The novelcyclooxygenase 2 selective inhibitors of the invention can be optionally nitrosated and/or nitrosylated. The invention also provides methods for treating inflammation,  pain and fever; for treating and/or improving the gastrointestinal propertie s of COX-2 selective inhibitors; for facilitating wound healing; for treating and/or preventing renal toxicity or other toxicities; for treating and/or preventing other disorders resulting from elevated levels of cyclooxygenase- 2; and for improving the cardiovascular profile of COX-2 selective inhibitors.< /SDOAB>
Patent CA-2434375-A1 (CA)
Inventor: DUPRAS SERGE
IPC: E06C1/39
Filed: 2003-07-08
Abstract: A storage structure for being used both as a container for storing a liquid and as a supporting structure for supporting an entity such as an object or a person.  The storage structure includes a base wall, a substantially opposed top wall and a peripheral wall extending between the base and top walls. The base, top and peripheral walls together form a liquid tight platform enclosure encompassing a liquid storing volume. The storage structure also has an inlet aperture and an outlet aperture both extending through the platform enclosure substantially adjacent respectively to the top wall and the base wall. The inlet and outlet apertures both establish fluid communication between the liquid storing volume and the exterior of the platform enclosure for respectively allowing filling and emptying of the liquid storing volume. An inlet aperture valve and an outlet aperture valve are operatively coupled respectively to the inlet and outlet apertures for allowing selective sealing obstruction respectively of the inlet and outlet apertures. The platform enclosure is configured, sized and made of a suitable material for allowing the platform enclosure to act both as a container for substantially sealingly storing the liquid and as a supporting structure for stably supporting thereon the entity.