baber/WOPTO huggingface dataset:
Patent WO-2020232135-A1 (WO)
Title: Systems, devices, and methods for treating vestibular conditions
Inventor: AKERS JONATHAN
IPC: A61M21/02
Filed: 2020-05-13
Abstract: Apparatus and methods are described herein that provide a vibratory device that can apply a vibratory signal to a user to treat physiological conditions, such as those associated with a vestibular system. The vibratory signal can be conducted via bone to target areas to provide therapeutic effects. The vibratory device can be used with a biometric sensor, which can be used to predict the onset of symptoms associated with a physiological condition and control the operation of the vibratory device (e.g., vary a force level or a frequency of the device, power on and off the device, etc.).
Patent WO-2020236575-A1 (WO)
Inventor: BARBOUR BLAIR
IPC: H01L27/146
Filed: 2020-05-15
Abstract: In a general aspect, integrated spatial phase wafer-level imaging is described. In some aspects, an integrated imaging system an integrated image sensor and an edge processor. The integrated image sensor may include: a polarizer pixel configured to filter electromagnetic (EM) radiation and to allow filtered EM radiation having a selected polarization state to pass therethrough; a radiation-sensing pixel configured to detect the filtered EM radiation and to generate a signal in response to detecting the filtered EM radiation; and readout circuitry configured to perform analog preprocessing on the signal generated by the radiation-sensing pixel. The edge processor may be configured to: generate first-order primitives and second-order primitives based on the analog preprocessed signal from the readout circuitry; and determine a plurality of features of an object located in a field-of-view of the radiation-sensing pixel based on the first-order primitives and the second-order primitives.
Patent WO-2021236079-A1 (WO)
Title: Calibrating print apparatus
Inventor: PEINADO GUTIERREZ DAVID
IPC: B41J29/38
Filed: 2020-05-20
Abstract: A print apparatus calibration method is disclosed. The method comprises printing, from each of a plurality of dies of a print head onto a printable substrate, an image in a first color according to a calibration pattern and an image in a second color according to the calibration pattern, the calibration pattern comprising a plurality of patches having a plurality of different densities. The method may comprise scanning, using a scanning unit, the images formed on the printable substrate to generate scanned image data, wherein the images in the first color are scanned by a first scanning module of the scanning unit and the images in the second color are scanned by a second scanning module of the scanning unit. The method may comprise analyzing, using processing apparatus, the scanned image data to identify any differences between printed densities of corresponding patches in different images of the same color. The method may comprise performing a calibration based on the analysis. A print apparatus and a machine-readable medium are also disclosed.
Patent WO-2020247695-A1 (WO)
Inventor: ASHURST DANIEL
IPC: A61L27/50
Filed: 2020-06-04
Abstract: Disclosed are example embodiments of methods and systems for delivering a medical implant. One of the systems includes an occlusive device with a braided elongate polymer body and a shape memory wire coupled with the polymer body. Various configurations for the occlusive device are disclosed. Also disclosed is a transfer tool for use with various delivery systems.
Patent WO-2020247942-A1 (WO)
Inventor: FRIEMAN MATTHEW
IPC: A61K39/145
Filed: 2020-06-08
Abstract: La présente invention concerne des compositions pharmaceutiques capables d'induire une réponse immunitaire chez un sujet, comprenant une quantité efficace d'un immunogène viral et d'un adjuvant, l'adjuvant comprenant un mimétique de lipide A. L'invention concerne également des méthodes permettant d'induire une réponse immunitaire.
Patent WO-2021016091-A1 (WO)
Title: Chimeric antigen receptors for direct and indirect targeting of fibronectin-positive tumors
Inventor: GOTTSCHALK STEPHEN
IPC: A61K39/395
Filed: 2020-07-17
Abstract: The application relates to a chimeric antigen receptor that directly and/or indirectly targets cells and their uses in tumor immunotherapy. The application also relates to polynucleotides that encode the chimeric antigen receptor and optionally accessory genes, vectors, and host cells comprising the chimeric antigen receptor and optionally a second antigen targeting moiety (e.g., a second chimeric antigen receptor or a bispecific molecule). The application also relates to methods for preparing host cells comprising the chimeric antigen receptor and optionally the second antigen targeting moiety.
Patent WO-2021021816-A1 (WO)
Inventor: IBRAHIM PRABHA
IPC: A61K31/415
Filed: 2020-07-28
Abstract: Methods of treating neurological diseases and disorders associated with protein aggregation using calpain inhibitors are provided. Said neurological diseases associated with protein aggregation include polyglutamine expansion diseases such as Huntington's disease, Machado-Joseph disease, and spinocerebellar ataxias.
Patent WO-2021030350-A1 (WO)
Inventor: AIED AHMED
IPC: A61L27/54
Filed: 2020-08-11
Abstract: Various embodiments disclosed relate to an implant including a crosslinked iodine-infused polyethylene. In various embodiments, the implant can be made by exposing the polyethylene to a source of iodine such that the polyethylene is infused with iodine. In various embodiments, a method of preventing microbe formation on or around an implant includes implanting a crosslinked iodine-infused implant comprising polyethylene, wherein iodine is released gradually from the implant after the implantation.
Patent WO-2021076212-A1 (WO)
Inventor: JIANG HAO
IPC: C23C16/56
Filed: 2020-08-14
Abstract: Methods for forming an interconnections structure on a substrate in a cluster processing system and thermal processing such interconnections structure are provided. In one embodiment, a method for a device structure for semiconductor devices includes forming a barrier layer in an opening formed in a material layer disposed on a substrate, forming an interface layer on the barrier layer, forming a gap filling layer on the interface layer, and performing an annealing process on the substrate, wherein the annealing process is performed at a pressure range greater than 5 bar.
Patent WO-2021034942-A1 (WO)
Title: Dietary supplements ameliorating dietary inadequacies related to brain health or neurodegenerative diseases, and methods to design same
Inventor: PARK EDWARD S
IPC: A61K31/51
Filed: 2020-08-19
Abstract: The dietary supplements of various embodiments comprise a water-soluble vitamin component, an oil-soluble vitamin component, magnesium or derivatives thereof, a primary polyphenolic compound, a secondary polyphenolic compound, and an omega-3-phospholipid complex. The methods include maintaining health, maintaining brain health and reducing the risk or rate of neurodegeneration or cognitive decline. Methods, including algorithms, for systematically determining a dietary supplement are also described.
Patent WO-2021055133-A1 (WO)
Title: Orientation determination based on both images and inertial measurement units
Inventor: ERIVANTCEV VIKTOR VLADIMIROVICH
IPC: G06N3/063
Filed: 2020-08-20
Abstract: A system to track orientations of parts of a user based on both images and inertial measurement units (IMUs). For example, the system receives images showing a portion of the user wearing sensor modules. The system receives a first set of orientation measurements generated by the sensor modules attached to some parts of the user. The system determines the second set of orientation measurements of one or more features of the portion of the user from the images. The system provides the first set of orientation measurements and the second set of orientation measurements as input to an artificial neural network that is configured to predict orientation measurements of the one or more other parts of the user that would be measured by additional sensor modules if the additional sensor modules were to be attached to the other parts of the user.
Patent WO-2021118654-A1 (WO)
Title: Suivi rf sans infrastructure dans des environnements d'intérieur dynamiques
Inventor: CHAKRABORTY AYON
IPC: G01S13/02
Filed: 2020-08-23
Abstract: L'invention concerne un procédé de suivi par radiofréquence (RF) sans infrastructure d'une pluralité de nœuds mobiles dans un environnement d'intérieur dynamique comprenant les étapes suivantes : équipement de chaque nœud individuel de la pluralité de nœuds situés dans l'environnement d'intérieur dynamique sans infrastructure avec une étiquette radio; détermination d'une estimation de la topologie de la pluralité de nœuds; détermination des emplacements relatifs de la pluralité de nœuds par génération de sous-graphes à noyau k rigide de l'estimation de topologie; transformation des emplacements relatifs en emplacements absolus; et délivrance en sortie des indices des emplacements absolus.
Patent WO-2021050530-A1 (WO)
Title: Distributed scheduler providing execution pipe balance
Inventor: DESAI SNEHA V
IPC: G06F9/48
Filed: 2020-09-09
Abstract: A processor includes a plurality of execution pipes and a distributed scheduler coupled to the plurality of execution pipes. The distributed scheduler includes a first queue to buffer instruction operations from a front end of an instruction pipeline of the processor and a plurality of second queues, wherein each second queue is to buffer instruction operations allocated from the first queue for a corresponding separate subset of execution pipes of the plurality of execution pipes. The distributed scheduler further includes a queue controller to select an allocation mode from a plurality of allocation modes based on whether at least one indicator of an imbalance at the distributed scheduler is detected, and further to control the distributed scheduler to allocate instruction operations from the first queue among the plurality of second queues in accordance with the selected allocation mode.
Patent WO-2021055604-A1 (WO)
Title: Systems, apparatuses, and methods for detecting ectopic electrocardiogram signals during pulsed electric field ablation
Inventor: VISWANATHAN RAJU
IPC: A61B5/364
Filed: 2020-09-17
Abstract: Systems, apparatus, and methods for ablation therapy are described herein, with a processor for confirming pacing capture or detecting ectopic beats. An apparatus includes a processor for receiving cardiac signal data captured by a set of electrodes, extracting a sliding window of the cardiac signal data, identifying a peak frequency over a subrange of frequencies associated with the extracted sliding window, detecting ectopic activity based at least on a measure of the peak frequency over the subrange of frequencies, in response to detecting ectopic activity, sending an indication of ectopic activity to a signal generator configured to generate pulsed waveforms for cardiac ablation such that the signal generator is deactivated or switched off from generating the pulsed waveforms. An apparatus can further include a processor for confirming pacing capture of the set of pacing pulses based on cardiac signal data.
Patent WO-2021055670-A1 (WO)
Title: Somatic cell-based electrical biosensor
Inventor: NIES CRAIG W
IPC: G01N27/327
Filed: 2020-09-18
Abstract: A biosensor having somatic cells immobilized on an electrode formed from a biologically inert material for sensing transepithelial/transendothelial electrical resistance is provided. The biosensor includes a working electrode formed from gold, graphene, carbon nanotube, or alloys or combinations thereof, having somatic cells formed directly thereon. With such a configuration, a very small sample size may be used while still eliciting an electrical response in the presence of a target composition.
Patent WO-2021062096-A1 (WO)
Title: Portes logiques à base de microarn et leurs utilisations
Inventor: WEISS RON
IPC: C12Q1/68
Filed: 2020-09-25
Abstract: La présente invention concerne, au moins en partie, concerne une porte logique à base de miARN qui comprend un support d'ARN modifié qui comprend un signal d'exportation nucléaire, un site cible pour un premier miARN et une séquence de pré-miARN pour un second miARN. L'invention concerne également des virus recombinants (par exemple, des virus adéno-associés recombinants (rAAV)) pour l'administration des portes logiques à base de miARN.
Patent WO-2021086538-A1 (WO)
Inventor: RECKER KARRIE LARAE
IPC: H04R1/10
Filed: 2020-09-30
Abstract: An ear-worn electronic system comprise a plurality of discrete devices configured for deployment at one ear of a wearer. The system comprises a first device configured for placement at least partially within an ear canal of the wearer. The first device comprises at least a first processor, one or more first microphones, a first speaker, a first rechargeable battery, and first charging circuitry. The system comprises a second device configured for placement at the wearer's ear proximal of the first device in an outer ear direction. The second device comprises at least a second processor, a second rechargeable battery, and second charging circuitry. The first device is configured to operate autonomously when operating in an independent mode relative to the second device. The first and second devices are configured to operate cooperatively when operating in a communicatively coupled mode.
Patent WO-2021072182-A1 (WO)
Title: Methods for producing ranibizumab
Inventor: OGEZ JOHN ROBERT
IPC: C12N1/38
Filed: 2020-10-09
Abstract: Provided herein are methods of producing a recombinant protein that include: providing a bacterium including a nucleic acid encoding a recombinant protein; and culturing the bacterium in a liquid culture medium including 0.1 g/L glycerol to about 10.0 g/L glycerol under conditions sufficient for the production and release of the recombinant protein into the culture medium. Also provided herein are methods of producing a recombinant protein that include: providing a bacterium including a nucleic acid encoding a recombinant protein; and culturing the bacterium in a liquid culture under conditions sufficient for the production and release of the recombinant protein into the culture medium, where the pH of the liquid culture medium is about 6.8 to about 7.5 during a growth phase and the pH of the liquid culture medium is about 6.0 to about 6.75 during a protein production phase.
Patent WO-2021076557-A1 (WO)
Inventor: SPIESS BRUCE DAVIS
IPC: C12Q1/686
Filed: 2020-10-14
Abstract: Compounds and compositions for determining the level of antithrombin (ATIII) in a sample are described. Methods of forming the compounds and compositions are also described. Methods of using the compounds and compositions to quantify the level of ATIII in a subject are further described. The methods can be used to facilitate determining a dosage or heparin or ATIII to administer to a patient.
Patent WO-2021091898-A1 (WO)
Title: Procédés et appareil de communication cv2x
Inventor: YOO DOOSUN
IPC: H04L1/00
Filed: 2020-11-03
Abstract: Des aspects de la présente invention comprennent des procédés, des appareils et des supports lisibles par ordinateur pour produire une pluralité de segments de message véhicule à tout cellulaire (CV2X) au niveau d'une première couche en fonction d'un message de couche supérieure au niveau d'une deuxième couche, chaque segment de message de la pluralité de segments de message CV2X comprenant un bloc de message d'une pluralité de blocs de message et un bloc redondant d'une pluralité de blocs redondants, transmettre la pluralité de blocs de message à un UE récepteur, et transmettre la pluralité de blocs redondants à l'UE récepteur après la transmission de la pluralité de blocs de message.
Patent WO-2021092398-A1 (WO)
Inventor: CHVALA JOSEPH
IPC: H01R4/70
Filed: 2020-11-06
Abstract: An electrical terminal for coupling to a conductive structure includes a body having a wire receiving portion for receiving a conductor. A cup portion is electrically coupled with the wire receiving portion and a boss portion extends from the cup portion. An overmold structure of insulation material is formed on the cup portion and covers the cup portion sides. An aperture is formed in the body and extends through the cup portion and the boss portion for receiving a post of the conductive structure for securing the terminal to the conductive structure. A fastener is configured for engaging a post and securing the boss portion against the conductive structure. The boss portion is configured to surround the aperture for providing an electrically conductive surface free from insulation material for interfacing with the conductive structure. The fastener and post are contained in the cup portion and an insulative cap is configured for engaging the overmold structure and sealing the cup structure around the fastener and post of a conductive structure.
Patent WO-2021108427-A1 (WO)
Title: Composés excipients pour formulations de biopolymères
Inventor: SOANE DAVID
IPC: A61K47/18
Filed: 2020-11-24
Abstract: L'invention concerne des formulations liquides à viscosité réduite comprenant une protéine et un composé excipient. L'invention concerne en outre des procédés de réduction de la viscosité d'une formulation liquide comprenant une protéine, des procédés de traitement et des procédés d'amélioration du traitement des protéines.
Patent WO-2021108435-A1 (WO)
Inventor: YANACEK DAVID C
IPC: G06F9/50
Filed: 2020-11-24
Abstract: Systems and methods are described for reducing cold starts code within a serverless code execution system by providing a set of environments reserved for the code. A frontend utilizes a consistent hash ring to distribute calls for execution among a set of manager devices that manage environments in the system, distributed in a manner that groups calls together and attempts to distribute calls of the same group to a stable subset of the manager devices. Each group is assigned an arc, representing a subset of manager devices. When a call is received to execute a set of code that has environments reserved, the frontend distributes the call to a manager device of a reserved arc. When a call is received to execute a set of code that does not have environment reserved, the frontend distributes the call to an arc associated with an arc for unreserved executions.
Patent WO-2021118959-A1 (WO)
Inventor: MAO YUANFENG
IPC: G05D1/02
Filed: 2020-12-08
Abstract: The present teaching relates to a method and system for path planning. Information of a current pose of a robotic arm having a plurality of operable segments is obtained. The information includes a plurality of values, each of which corresponds to an angle formed between consecutive operable segments of the robotic arm. A desired pose where the robotic arm needs to reach is also obtained. An angle step-value is computed for the current pose of the robotic arm based on a function of a distance between the current pose and the desired pose, wherein the angle step value is to be used to determine a plurality of candidate next poses of the plurality of operable segments. One or more of candidate next poses is selected based on at least one criterion, and a trajectory is determined from the current pose to the desired pose based on the selected next poses.
Patent WO-2021126631-A1 (WO)
Title: Communication periods for multi-usim and dual connectivity operation
Inventor: OZTURK OZCAN
IPC: H04W88/06
Filed: 2020-12-09
Abstract: Certain aspects of the present disclosure provide techniques for multi-universal subscriber identification module (USIM) and dual connectivity operation. A method that may be performed by a user equipment (UE) includes establishing a first access link, associated with a first subscriber identification module (SIM) of the UE, for communicating with a first base station; establishing a second access link, associated with the first SIM of the UE, for communicating with a second base station; establishing a third access link associated with a second SIM of the UE; identifying at least one time division multiplexing (TDM) pattern indicating a set of time periods during which to use the third access link; and tuning to the third access link for communicating using the second SIM during at least one time period of the set of time periods indicated in the TDM pattern.
Patent WO-2021126915-A1 (WO)
Title: Techniques for improved automatic drug delivery performance using delivery tendencies from past delivery history and use patterns
Inventor: ZADE ASHUTOSH
IPC: A61M5/142
Filed: 2020-12-16
Abstract: Disclosed are devices, a system, methods and computer-readable medium products that provide techniques to implement functionality to determine when to softened upper bounds of drug delivery and how much to soften the upper bound. Future blood glucose measurement values may be predicted by calculating deviations between predicted blood glucose measurement values and additional blood glucose measurement values. A gain parameter may be determined for use with a model of predicting a users blood glucose measurement values and determining future drug dosages. Safety constraints may be determined based on an evaluation of missing blood glucose measurement values. In addition, safety constraints may be determined based on an evaluation of a user's increased interaction with an automatic drug delivery device. A bolus uncertainty metric to determine an amount of insulin to be provided in a bolus dosage in response to a bolus request may be calculated.
Patent WO-2021127439-A1 (WO)
Title: Dynamic content insertion on a user-by-user basis
Inventor: MAJOR ROBERT DREW
IPC: H04N21/442
Filed: 2020-12-18
Abstract: Various arrangements for performing dynamic content insertion are presented. A user profile may be identified as active at a television receiver based on the user profile being mapped to a current television viewing session. A plurality of content items that have been output for presentation while the user profile is active may be tracked across a plurality of television viewing sessions. A set of insertion rules may be evaluated that are mapped to a content item. The content item may be determined to have met an output threshold for the user profile. An alternative piece of content may be selected for insertion based on the set of insertion rules and determining that the content item has met the output threshold for the user profile. The television receiver may be triggered to substitute the alternative content item into a television channel stream to replace the content item.
Patent WO-2021142167-A1 (WO)
Title: Homogeneous sheet excluding polyvinyl chloride
Inventor: Zhang water
IPC: B29B9/04
Filed: 2021-01-07
Abstract: Included is a homogeneous sheet, which excludes polyvinylchloride. The sheet includes a polyurethane, a synthetic rubber blend, and a filler. The synthetic rubber blend may include a pre-mix of a synthetic rubber and white oil.
Patent WO-2021146110-A1 (WO)
Title: Introducer sheath with camming tip
Inventor: Cummings Brendan
IPC: A61F2/95
Filed: 2021-01-08
Abstract: An introducer sheath system includes a sheath member defining a tubular structure extending between a proximal end and a distal end of the sheath. The system includes a tip portion provided at the distal end of the sheath member. The tip portion defines a tubular structure extending between a proximal end and a distal end of the tip portion. The tip portion has a central lumen extending therethrough. The tip portion includes a camming feature formed as a protrusion from the central lumen of the tip portion. The tip portion is movable between a non-expanded configuration when the camming feature is not engaged and an expanded configuration when the camming feature is engaged. When the tip portion is in the non-expanded configuration, a diameter of the distal end of the tip portion is less than a diameter of the proximal end of the tip portion.