Patent EA-000817-B1 (EA)
Title: Anticeptic skin care composition and method for making same
Inventor: GUILBAUD JEAN
IPC: A61K8/00
Filed: 1996-09-11
Abstract: 1. A skin care and/or cosmetic composition with antiseptic-typeantibacterial activity in the form of "an oil-in water" emulsion containing 0,025 to 1% by weight of a chelating agent, such as polyaminocarboxylic acid a salt thereof for applying on a damaged or healthy skin, characterized in that containing a basic chlorhexidine present in the oil phase of said emulsion and a chlorhexidine salt present in the aqueous phase of said emulsion, wherein the total concentration being 0,05 to 1% by weight. 2. A composition of claim 1, characterized in that further contains 0,025 to 1% by weight of primary, secondary or tertiary aliphatic alcohol and/or lower phenylalkyl alcohol, such as benzyl, phenylethyl or phenylpropyl alcohol. 3. A composition of claim 1 or 2, characterized in that contains disodium salt of etylenediaminetetraacetic acid as polyaminocarboxylic acid. 4. A composition of claim 1 to 3, characterized in that contains about 75% by weight of purified water, about 20% of grease substances and about 5% of other additional components, such as antiseptic agents, fungicidal, binding, conserving, perfumed. 5. A composition of claim 1 to 4, characterized in that contains surface-active agent comprising ethyleneglycol stearate and trolamine stearate obtained in the result of neutralization of stearic acid with trolamine. 6. A composition of claim 1 to 5, characterized in that having the following composition:   % by wt 1. - Ethyleneglycol stearate 5,450 2. - Stearic acid 3,625 3. - Cetylepalmitate 0,350 4. - Solid paraffine 1,600 5. - Liquid light paraffine 6,850 6. - Perhydrosqualene 1,500 7. - Avocado oil 1,000 8. - Propyleneglycol 2,300 9. - Trolamine and sodium alginate 0,702 10. - Trolamine 0,670 11. - Potassium sorbate 0,134 12. - Disodium salt of EDTA acid 0,100 13. - Benzyl alcohol 0,200 14. - Chlorhexidine 0,023 15. - 20% solution of chlorhexidinedigluconate 0,725 16. - Purified water remaining to reach 100%   7. A composition of claim 1 to 6, characterized in that its pH is about 7. 8. A composition of claim 1 to 7, characterized in that its viscosity is 5.10<-3> to 6 Pa.s. 9. A composition of claim 1 to 8, characterized in that itshydophile/lipophile balanceisfrom 3 to 30. 10. A composition of claim 9, characterized in that represents a form of homogenous dispersion of vesicle of oil phase 2 to 20 μm in size in the aqueous phase. 11. A method for making a composition of claim 1 to 10, characterized in that preparing: a) an aqueous phase containing the following components: - purified water - trolamine and sodium alginate - trolamine - potassium sorbate - disodium salt of EDTA acid, and, if necessary - benzyl alcohol b) an oil phase containing the following components: - ethyleneglycol stearate - stearic acid  cetylepalmitate - solid paraffine - liquid light paraffine - perhydrosqualene - avocado oil - propyleneglycol, and, if necessary - basic chlorhexidine with further dispersion of the oil phase into the aqueous phase with the proviso of constant agitation and maintaining appropriate temperatures and adding to thus obtained emulsion an aqueous solution of chlorhexidine salt and agitating the compound at a temperature from 20 degree C to 50 degree C. 12. A method of claim 11, characterized in that different components of the aqueous phase are added to the purified water is intensely agitated at a temperature of about 70 degree C. 13. A method of claim 11 or 12, characterized in that disodium salt of EDTA acid is added at the enduring preparation of the aqueous phase. 14. A method of claim 11 to 13, characterized in that the oil phase is prepared by mixing different its components at a temperature of about 70 degree C to obtain melted oil phase. 15. A method of claim 14, characterized in that chlorhexidine is added at the end. 16. A method of claim 11 to 15, characterized in that emulsification is carried out at a temperature of about 70 degree C.