baber/WOPTO huggingface dataset:
Patent MX-2021015270-A (MX)
Title: Use of bispecific antigen-binding molecules that bind muc16 and cd3 in combination with 4-1bb co-stimulation.
Inventor: KIRSHNER JESSICA R
IPC: C07K16/28
Filed: 2020-06-19
Abstract: Provided herein are method of treating cancer using bispecific antigen-binding molecules that bind to Mucin 16 (MUC16) and CD3. According to certain embodiments, the antibodies useful herein bind human MUC16 with high affinity and bind CD3 to induce human T cell proliferation. According to certain embodiments, bispecific antigen-binding molecules comprising a first antigen-binding domain that specifically binds human CD3, and a second antigen-binding molecule that specifically binds human MUC16 are particularly useful herein. In certain embodiments, the bispecific antigen-binding molecules in combination with an anti-4-1BB agonist are capable of inhibiting the growth of tumors expressing MUC16, for example, ovarian tumors. The bispecific antigen-binding molecules in combination with an anti-4-1BB agonist are useful for the treatment of diseases and disorders in which an upregulated or induced targeted immune response is desired and/or therapeutically beneficial, for example, in the treatment of various cancers.
Patent MX-2021015494-A (MX)
Title: Quinazoline prodrugs for the treatment of viral infections and further diseases.
Inventor: MC GOWAN DAVID CRAIG
IPC: A61P31/00
Filed: 2020-06-18
Abstract: Provided herein are compounds of formula (I), pharmaceutical compositions comprising such compounds, and methods of using such compounds through induction of the T helper 1 (Th1) immune response to treat infections, diseases, and disorders. The compounds disclosed herein may also be considered prodrugs and vaccine adjuvants.
Patent MX-2022001453-A (MX)
Title: A multilayer structure for automotive components.
Inventor: GASTALDI FRANCESCO
IPC: B32B5/26
Filed: 2020-08-06
Abstract: The invention concerns a multilayer structure comprising: - two outer layers Î±1, made of a non-woven material; - at least one intermediate layer Î², made of a glass wool material; - at least one intermediate polyurethane layer ï§; wherein the at least one intermediate polyurethane layer Î³ is made of polyurethane deriving from polyurethane automotive scraps, and wherein the at least one intermediate polyurethane layer Î³ has a density value in the range from 20 to 30 g/l.
Patent MX-2022004717-A (MX)
Title: Dosing indicator.
Inventor: WANG SAMANTHA CHEN- YEE
IPC: A61C19/06
Filed: 2020-11-23
Abstract: Devices with one or more dosing indicator symbols to signal to a user how much material should be dispensed. A whitening pen with a first dosing indicator on the body and a second dosing indicator on the rotating portion that can allow a user to dispense a known amount of a whitening composition.
Patent MX-2022005886-A (MX)
Title: Glp-1 receptor agonist and use thereof.
Inventor: PARK JUNG-EUN
IPC: A61P3/10
Filed: 2020-11-13
Abstract: Disclosed are novel compounds of Chemical Formula 1, optical isomers of the compounds, and pharmaceutically acceptable salts of the compounds or the optical isomers. The compounds, isomers, and salts exhibit excellent activity as GLP-1 receptor agonists. In particular, they, as GLP-1 receptor agonists, exhibit excellent glucose tolerance, thus having a great potential to be used as therapeutic agents for metabolic diseases. Moreover, they exhibit excellent pharmacological safety for cardiovascular systems.
Patent MX-2022005994-A (MX)
Title: Use of fak inhibitor in preparation of drug for treating tumors having nras mutation.
Inventor: JIANG JUN
IPC: A61K31/4439
Filed: 2020-11-17
Abstract: A use of a FAK inhibitor in the preparation of a drug for preventing and/or treating tumors having an NRAS mutation. A method for treating tumors that have experienced an NRAS mutation, which comprises administering an effective dose of a FAK inhibitor to an individual. A FAK inhibitor for treating tumors having an NRAS mutation. The FAK inhibitor is BI853520, defactinib, GSK2256098, PF-00562271, VS-4718 or a pharmaceutically acceptable salt thereof.
Patent MX-2022006226-A (MX)
Title: Mechatronic equipment for testing control modules that stabilize three-dimensional dynamic systems modeled as inverted pendulums.
Inventor: HUERTA ÁVILA HECTOR
IPC: G05B19/00
Filed: 2022-05-23
Abstract: The present invention relates to mechatronic equipment to test control modules that stabilize three-dimensional dynamic systems modeled as inverted pendulums. Said equipment includes a stationary base that supports the other elements that make up the mechatronic equipment, a mobile platform rotatably interconnected to a first positioning mechanism that makes it rotate, placed therein, a second positioning mechanism, a third positioning mechanism arranged and interconnected to the second positioning mechanism, a fourth locator mechanism arranged and interconnected to the third locator mechanism, and an emulator body of dynamic systems set in the fourth positioning mechanism. Also, it aims to provide mechatronic equipment to test control modules that stabilize three-dimensional dynamic systems modeled as inverted pendulums, allowing stabilizing dynamic systems of up to six degrees of freedom with up to four actuators.
Patent MX-2022006709-A (MX)
Title: Anti-idiotypic antibodies to bcma-targeted binding domains and related compositions and methods.
Inventor: HAUSKINS COLLIN
IPC: C07K16/28
Filed: 2020-12-04
Abstract: Provided are anti-idiotype antibodies that specifically recognize anti-BCMA antibody moieties, in particular, anti-BCMA antibody moieties present in recombinant receptors, including chimeric antigen receptors (CARs). The disclosure further relates to uses of antiidiotype antibodies for specifically identifying and/or selecting cells expressing such recombinant receptors, such as anti-BCMA CAR T cells. The disclosure further relates to uses of anti-idiotype antibodies for specifically activating such cells.
Patent MX-2022008897-A (MX)
Title: Self regulating heater in an intermediate bulk container.
Inventor: BLAKE JAMES T
IPC: B65D81/18
Filed: 2022-07-19
Abstract: A method for establishing and/or maintaining a desired temperature of a material in an intermediate bulk container including the steps of positioning a heating element in at least partial contact with a material container containing the material within the intermediate bulk container; and applying an electrical power source to the heating element, wherein the heating element is at least partially made of a positive temperature coefficient resistant material, the heat from the heating element being largely transferred to the material in the material container.
Patent MX-2022009339-A (MX)
Title: System for providing powerline communication over flexible mesh for circuit design used in biometric monitoring.
Inventor: BOGDANOVICH PHILLIP
IPC: H02J1/08
Filed: 2021-01-28
Abstract: A system for providing powerline communication over flexible mesh for circuit design used in biometric monitoring is disclosed. In particular, the system provides for the transmission of power and data over the same circuit infrastructure, and integrates the ability to transfer data over an infrastructure that also transmits power. Notably, the system facilitates the integration of data over power in flexible systems, such as systems incorporating flexible mesh sensors and flexible geometric systems. The dual use of power infrastructure reduces weight and increases flexibility and potential sensor density. The systems use of data over power significantly reduces or eliminates the needs for a standalone data bus, thereby reducing the design complexity of the circuit.
Patent MX-2022009342-A (MX)
Title: Automated line blind.
Inventor: JIMENEZ FILIBERTO
IPC: F16K1/46
Filed: 2021-02-03
Abstract: A low-weight, low material automated line valve with sealing mechanism which can seal with the blind in either the open or closed position, and bias mechanism to improve the seal.
Patent MX-2022009619-A (MX)
Title: Highly stretchable adhesive silicone compositions and uses thereof as sealing/bonding agents.
Inventor: THIRIA REMI
IPC: C09J183/04
Filed: 2021-02-04
Abstract: A curable silicone adhesive having improved elongation-at-break and adhesive properties to various substrates, in particular synthetic textiles used in the manufacture of air bags, to be used, for example, as a joint sealer. These silicone compositions provide excellent adhesive properties such as peel strength and cohesive failure when used to seal joints/seams between two pieces of textile fabric. Airbag fabrics using such novel addition curable adhesive silicone compositions are also provided.
Patent MX-2022011767-A (MX)
Title: Treatment of solid cancerous tumors by oral administration of a halogenated xanthene.
Inventor: DEES H CRAIG
IPC: A61K39/395
Filed: 2021-03-26
Abstract: The present invention contemplates a method of treating a solid cancerous tumor in a mammalian subject by the oral administration of a solid cancerous tumor-effective amount of a halogenated xanthene (HX), the lactone thereof, a pharmaceutically acceptable salt, or a C1-C4 alkyl or aromatic ester thereof (collectively an HX compound) to that mammalian subject, and liquid and solid pharmaceutical compositions for administering the HX compound. In addition, a method of inhibiting the growth of a GI tract carcinoma of a mammalian subject by the oral administration of a solid cancerous tumor-effective amount of an HX compound, as well as solid and liquid pharmaceutical compositions therefor.
Patent MX-2022013502-A (MX)
Title: Materials and methods for treating juvenile idiopathic arthritis.
Inventor: LEU JOCELYN
IPC: C07K16/24
Filed: 2021-04-26
Abstract: The present invention relates to compositions and methods utilizing anti-TNF antibodies, e.g., the anti-TNF antibody golimumab having a heavy chain (HC) comprising an amino acid sequence of SEQ ID NO:36 and a light chain (LC) comprising an amino acid sequence of SEQ ID NO:37, for use in the treatment of juvenile idiopathic arthritis (JIA), and in particular for polyarticular juvenile idiopathic arthritis (pJIA).
Patent MX-2022014410-A (MX)
Title: Il1-r1 derived inhibitor of il-1b and use thereof.
Inventor: LAVROVSKY YAN
IPC: C07K14/545
Filed: 2020-05-22
Abstract: A therapeutic composition is described that can be used for treating or prevention of diseases association with modulation of activity of human IL-1Î². In certain aspects, the disclosed composition is based on engineering of a heterodimeric protein assembly that is capable of binding to human IL-1Î² and attenuating its function. The heterodimeric protein assembly comprises extracellular portions of human IL1-R1 and of human IL-1RAcP, or their functional fragments. Each, the IL1-R1 portion and the IL-1RAcP portion, is fused to a distinct mutant of Fc portion of the human Ig Gamma-1. The two distinct Fc mutants in the heterodimeric protein assembly are engineered as to favor the heteromeric dimer formation between the two Fc mutants over any homomeric assembly. The therapeutic composition has been formulated for administration into humans and animals.
Patent MX-PA00000360-A (MX)
Inventor: HERBOTS IVAN MAURICE ALFONS JA
IPC: A61K8/00
Filed: 1997-07-09
Abstract: The present invention relates to cleaning compositions, including laundry, dishwashing, hard surface cleaner, oral/dental cleaning compositions, comprising a proteinic substrate based oxygenase, which provide effective and efficient cleaning of proteic based stains and/or soils such as protein containing food stains/soils and everyday body soils and provide sanitisation of the treated surfaces. Furthermore, the cleaning compositions of the present invention provide fabric realistic items cleaning and whitening performance when formulated as a laundry detergent composition.
Patent MX-PA00009830-A (MX)
Title: Dna immunization against chlamydia.
Inventor: BRUHNAM ROBERT C
IPC: C07K16/40
Filed: 1999-04-07
Abstract: A nucleic acid, including DNA, for immunization, in order to generate a protective immune response in a host, including humans, against a major outer membrane protein of a Chlamydia strain, which preferably contains a nucleotide sequence encoding for a fragment that generates antibodies that specifically react with MOMP and a promoter sequence operably coupled to the first nucleotide sequence for the expression of the MOMP fragment in the host. The non-replicating vector can be formulated with a pharmaceutically acceptable carrier for administration in vivo to the host.
Patent MX-PA01000024-A (MX)
Title: Adjustable retainer for electrical cords.
Inventor: CAROL A HOWARD
IPC: H01R13/58
Filed: 2001-01-08
Abstract: A housing for an electrical wiring device includes an adjustable clamping mechanism for retaining electrical conduits therein. The clamping mechanism has a pair of opposing strain relief members on opposite sides of a conduit passageway, set to accept a predetermined conduit width. Each strain relief member has a frangible portion which can be removed by a user. In this manner, if a user desires to retain, by means of an interference fit, a conduit having a diameter larger than the predetermined spacing of the intact strain relief members will allow, one or both frangible portions can be removed to accommodate a larger sized conduit. Alternatively, more than one pair of strain relief members having frangible portions can be alternately arranged to clamp a conduit in an S-shaped configuration, capable of accepting multiple conduit sizes by removing some or all of the frangible portions. Preferably, the strain relief members are integrally formed with the housing, and each frangible por tion is integrally formed with the remainder of the strain relief member and the housing.
Patent MX-PA01007367-A (MX)
Title: Rigid hinged-lid packet.
Inventor: DRAGHETTI FIORENZO
IPC: B65D5/06
Filed: 1999-07-16
Abstract: A rigid packet (1) with a hinged lid (5) for cigarettes (2) has a front wall (6) and a rear wall (7), each curving outwards and having a respective flat central portion (12) and two curved, preweakened lateral bands (17) connecting the relative flat central portion (12) to two flat lateral walls (8) of the packet (1) at respective sharp edges (9).
Patent MX-PA01008850-A (MX)
Title: Indicia carrier.
Inventor: ITZCHAK BAR-YONA
IPC: G09F3/02
Filed: 2001-08-31
Abstract: An indicia carrier film suitable for producing consecutively changing images in harmonious fashion. The indicia carrier includes a display unit housing provided with at least one panel formed from an array of linear lenses, a displaceable indicia carrier film which is disposed within the housing at a distance from the rear face of the lenticular panel equaling the focal length of the lenses, and a drive means for periodically displacing the indicia carrier relative to the lenses. The ratio of film weight to surface area is greater than 1:100 gm/cm2. The total weight of the film is not greater than 10 gm for an indicia carrier of approximate A4 dimensions (17x29.5 cm). The modulus of elasticity is of at least 600 Mpa.
Patent MX-PA01009053-A (MX)
Title: Aerated confectionery product and method of preparation.
Inventor: ZIETLOW PHILIP K
IPC: A23G3/52
Filed: 2000-01-31
Abstract: Disclosed are aerated food products, especially marshmallows, having a nutritionally fortifying ingredient and improved methods for a method for preparation. The aerated food products comprise 50 to 98 % of a saccharide component; about 0.5 to 30 % of a structuring agent; about 1 to 30 % moisture; about 0.01 % to 15 % of nutritional fortifying ingredient selected from the group consisting of biologically active components, fiber, micro-nutrients, minerals and mixtures thereof. The aerated food products have a density of about 0.1 to 1.0 g/cc. The methods of preparation comprise the steps of: A. providing a liquid sugar confection blend comprising: about 50 to 98 % of a saccharide component; about 1 to 30 % moisture; and, about 1 to 30 % (dry weight basis) of a foam structuring agent; B. adding the liquid confection blend about 0.01 % to 45 % of a dry particulate having a particle size distribution such that 90 % have a particle size of less than 400 mum to form a liquid confection blend; aerating the liquid confection blend to form an aerated confection plastic foam having a density of about 0.1 to 1.0 g/cc; and extruding the aerated foam at a temperature of about 105 to 150 °F to form an aerated confection extrudate; cooling the extrudate to solidify the confection to form a set aerated confection extrudate; forming the set aerated confection extrudate into pieces; and, drying the pieces to a moisture content of about 1 to 5 % to form dried aerated confection pieces. Dried calcium fortified aerated marshmallow food products find particular suitability for use as ingredients for children's RTE cereals.
Patent MX-PA01011576-A (MX)
Title: Semi-rigid profile system for the continuous assembly of agglomerated boards for furniture manufacturing.
Inventor: HUMBERTO OROZCO GAVALDON
IPC: A47B95/04
Filed: 2001-11-13
Abstract: A semi-rigid profile system for the continuous assembly of agglomerated board for the manufacturing of pieces of furniture such as closets, wardrobes, chest of drawers, or racks, including: a group of trough shaped profiles with variously shaped internal structure to be fastened onto the side edges of normal or reinforced agglomerated boards, characterized because it is embedded into the edges through one single profile structure by means of bending at the ends of the board facilitated by 45.degree angle cuts.
Patent MX-PA01012557-A (MX)
Title: Personal mobility vehicles and methods.
Inventor: AMSBURY BURL
IPC: A61G5/04
Filed: 2000-06-01
Abstract: A class of transportation vehicles for carrying an individual (10) over ground having a surface that may be irregular. Various embodiments have a motorized drive, mounted to the ground-contacting module (6) that causes operation of the vehicle in an operating position that is unstable with respect to tipping when the motorized drive arrangement is not powered. Related methods are provided.
Patent MX-PA01013339-A (MX)
Title: Method for managing urban wastewater based on indications on pollutants.
Inventor: CAULET PHILIPPE
IPC: C02F3/00
Filed: 2000-06-29
Abstract: The invention concerns a method for conducting and managing installations of urban wastewater treatment on the basis of estimates of the influent polluting loads. The invention is characterised in that said estimates are derived from continuously measuring the influent rate, the conductivity and the turbidity of the raw water to be treated, in the following sequence: continuously measuring the instantaneous values of the conductivity and turbidity of the water to be treated; estimating the polluting matter concentration of the raw water on the basis of said measured conductivity and turbidity values; continuously measuring the flow rate of the raw water to be treated; calculating the polluting matter load of the raw water to be treated on the basis of its flow rate; and determining downstream actions to be taken to eliminate the estimated total load of the polluting element (E).
Patent MX-PA02001776-A (MX)
Title: Apparatus for creating a continuous annular lesion.
Inventor: DONALD PATTERSON
IPC: A61B18/14
Filed: 2000-09-07
Abstract: A medical device is disclosed which includes a deformable electrode device (12). In one illustrative embodiment, the deformable electrode is in the form of a braided member, at least a portion of which is electrically conductive. The braided member is extended over an elongated inner member (14), such as a guide wire, catheter shaft, or the like. A proximal sheath (22) is slidably extended over the inner member and is connected to the braided, electrically conductive member. The proximal sheath may be advanced distally to deform the braided member so that it defines a distally facing, ablative ring (40), and is operative to form an annular lesion.
Patent MX-PA02007364-A (MX)
Title: A process for contour control machining of metal blocks.
Inventor: OLEKSY HENRYK
IPC: G06F17/50
Filed: 2000-01-18
Abstract: The invention comprises a computer aided program for milling machine to machine precise concave and convex surfaces within a metal block to form the base section of a turbine blade called the root section (1). The root section (1) of the turbine blade is designed to fit within precise tolerances upon a circular rotor. Because of the curvatures of the mating surface of the root section and the mating section of the circular rotor, the machining of the root section of the turbine blade requires convex movements of the form cutter tool (9) and rotating of the rotary table (7) which holds the turbine blades. The invention teaches a method of determing machining instructions for machining of a workpiece using a machine having a cutter (9), the surfaces of the workpiece being defined by a plurality of programmed instructions obtained by trigonometric analysis of the required surface curvatures.
Patent MX-PA02008818-A (MX)
Title: Il 8 receptor antagonists.
Inventor: JIN QI
IPC: C07D249/04
Filed: 2001-03-09
Abstract: This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin 8 (IL 8).
Patent MX-PA02010932-A (MX)
Title: Procedure for the preparation of meloxicam micro-spheres (4-hydroxy-2-methy-n-(5-methyl-2- thiazolyl)-2h-1,2- benzothiazine -3- carboxamide -1,1- dioxide) with negative floatability.
Inventor: POOT LOPEZ FERNANDO
IPC: A61K9/62
Filed: 2002-11-07
Abstract: A procedure for the preparation of meloxicam micro-spheres with negative floatability in medicaments, starting with inert nuclei, covered in a fluidized bed system, in which a first layer of sodium laurysulphate, polyethylene glycol, hydroxypropyl methyl cellulose and meloxicam; a second layer containing a hydrophilic polymer which is the polyethylene glycol; this application is able to provide a novel notability of the system or negative notability.
Patent MX-PA03000547-A (MX)
Title: Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder.
Inventor: SHIRVAN MITCHELL
IPC: A61P25/18
Filed: 2001-07-20
Abstract: A method for the treatment of mania in bipolar disorder using derivatives of valproic acid and 2-valproenic acid amines having the following structures: wherein R1, R2, and R3 are independently the same or different and are hydrogen, a C1-C6 alkyl group, an aralkyl group, or an aryl group, and n is an integer which is greater than or equal to 0 and less than or equal 3, or a compound containing a valproic or a 2-valproenic moiety, as well as pharmaceutical compositions comprising these derivatives or compounds.
Patent MX-PA03002412-A (MX)
Inventor: LI WENYING
IPC: A61K45/06
Filed: 2001-06-20
Abstract: Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds.
Patent MX-PA03004390-A (MX)
Title: Piperazinylpyrazine compounds as agonist or antagonist of serotonin 5ht-2 receptor.
Inventor: NILSSON BJORN
IPC: C07D239/48
Filed: 2001-11-20
Abstract: A compound of the general formula (I), wherein R1, R2, X, Y and Z are as described in the specification.
Patent MX-PA03004990-A (MX)
Title: Aqueous additives in hydrocarbonaceous fuel combustion systems.
Inventor: GREGORY H GUINTHER
IPC: F01N13/02
Filed: 2003-06-04
Abstract: An aqueous additive containing a metal compound is used to improve the operation of combustion exhaust after treatment systems. The additive is introduced into the combustion chamber as part of an emulsion with the fuel or, alternatively, in the emulsion or alone as an aqueous stream introduced into the exhaust or emission path. The metal compound scavenges combustion byproducts in order to protect and make more efficient the after treatment system.