baber/WOPTO huggingface dataset:
Patent IE-891976-L (IE)
Title: Propeptides
IPC: C12N15/17
Filed: 1989-06-19
Abstract: The invention relates to insulin precursors having the amino acid sequence  B(1-29)-X1-X2-Y2-Y1-A(1-21) wherein B(1-29) are the 29 first amino acid residues of the B chain of human insulin, A(1-21) are the 21 amino acid residues of the A chain of human insulin, X1 represents a peptide bond or one or more amino acid residues, X2 represents Glu or Asp, and Y1 and Y2 each represent Lys or Arg, the positions A6 and A11, A7 and B7 and A20 and B19, respectively, being connected through sulphur bridges, and, optionally, one or more of the amino acid residues of chains B(1-29) and A(1-21) are substituted by another amino acid residue. The insulin precursors are prepared by culturing a yeast strain transformed with a replicable expression vehicle comprising a DNA sequence encoding the insulin precursor and isolating it from the culture medium. The insulin precursors can be converted into human insulin or insulin analogues by enzymatic treatment.
Patent IE-842009-L (IE)
Title: Improved barium sulfate for use as a radiographic contrast¹agent
IPC: A61K49/04
Filed: 1984-08-03
Abstract: Barium sulfate suitable for the preparation of radiographic contrast agents of increased flowability and density is obtained by a high temperature treatment at 700 DEG  to 1,200 DEG  C. and preferably at 800 DEG  to 1,000 DEG  C. The barium sulfate so sintered is distinguished by a bulk density of 2.5 to 3 g/ml and its aqueous suspension, containing 200 g of barium sulfate per 100 ml, is distinguished by a viscosity of no more than 1,000 mPas. Radiographic contrast agents containing at least 200 g of sintered barium sulfate per 100 ml are outstandingly suitable for the difficult double contrast visualization of the stomach and gastric mucosa.
Patent IE-39929-L (IE)
Title: Gypsum article
IPC: C04B11/024
Filed: 1974-10-03
Abstract: 1481788 Gypsum BPB INDUSTRIES Ltd 8 Oct 1974 [25 Oct 1973] 49749/73 Heading C1A [Also in Division E1] The tendency of gypsum articles to sag in damp conditions is reduced by incorporating gallic acid (preferably in a proportion of 0À01 to 0À04 wt. per cent of the gypsum, calculated as calcium sulphate hemihydrate). The gallic acid may be added to the gypsum plaster, or gypsum and gallic acid may be mixed and then calcined to form a plaster; in either case, the plaster is then mixed with water and the articles are shaped in conventional manner.
[GB1481788A]
Patent IE-902133-L (IE)
Title: Water treatment process
IPC: C02F1/58
Filed: 1990-06-13
Abstract: Acid water containing toxic levels (> 0.1 ppm) of aluminium is treated to dissolve therein both silicate ions in an amount to create a solution containing at least 40, preferably at least 100, micromoles per litre of silicon and a silicon:aluminium ratio (based on metals) of at least about 6:1 and preferably 10:1 in the water to form a non-toxic complex with aluminium and alkali or alkali metal ions to increase the pH of the water. The preferred treatment agent is a hydraulic calcium silicate, in the form of cement clinker, optionally silicate-enriched with a soluble silicate.
Patent IE-882264-L (IE)
Title: Serum free media for the growth of insect cells and expression of products thereby
IPC: C12N15/866
Filed: 1988-07-22
Abstract: Serum-free media which support the growth of insect cells and the production thereby of recombinant proteins and viral products are herein disclosed. The serum free media can support insect cell growth at large scale under agitated and/or sparged, preferably well-aerated conditions. The serum free medium disclosed support insect cell growth to cell densities comparable to serum-containing culture and the production of viral and recombinant products to levels equivalent to those found in serum containing culture.
Patent IE-862365-L (IE)
Title: Acrylic adhesive compositions
IPC: C09K3/10
Filed: 1986-09-04
Abstract: The hot strength of acrylic adhesives containing an acid releasing polymer, e.g. chlorosulphonated polyethylene, particularly two-part adhesives, is increased by substituting as all or part of the acrylate ester component an epoxy containing acrylate or methacrylate, i.e. containing an epoxy group in the ester moiety, and in particular epoxidised dicyclopentenyloxyethyl acrylate or methacrylate, or glycidyl acrylate or methacrylate.
[EP0218365A1]
Patent IE-832452-L (IE)
Title: Lymphocyte growth factor
IPC: C07K14/52
Filed: 1983-10-19
Abstract: A family of growth factors, methods of making and using such growth factors in in vivo treatment of living mammalian cells, and products incorporating such growth factors, are disclosed. The growth factors were isolated from the supernatant fluid obtained by incubation of inducer T-cells in the presence of a suitable antigen or mitogen. The growth factors disclosed include a 14 Kd polypeptide which stimulates growth of both T-cells and B-cells, a 50 Kd polypeptide which stimulates B-cells to multiply and secrete immunoglobulins, and a 45 Kd growth factor which stimulates secretion of immunoglobulins by B-cells and stimulates rapid growth of certain mast cells, stem cells and certain other types of cells.
[US4613459A]
Patent IE-44509-L (IE)
Title: Semi-synthetic oleandomycins
IPC: A61P31/04
Filed: 1976-11-23
Abstract: Disclosed herein is a novel series of semi-synthetic oleandomycins having an exocyclic methylene or a cyclopropyl group at the C8 position. Processes for preparing the methylene compounds from the natural oleandomycins and the cyclopropyl compounds from the methylene compounds are also disclosed. The above oleandomycin compounds are effective in inhibiting the growth of microorganism, especially Gram-positive microorganism.
[CA1069503A]
Patent IE-822905-L (IE)
Title: Disposable diaper
IPC: A61F13/514
Filed: 1982-12-07
Abstract: A disposable diaper having cushioned elasticized leg hold edges formed from elastic members secured between the backing sheet and the absorbent pad or mounted directly in the absorbent pad and adapted to overcome leakage through the leg hold edges while cushioning so as not to make indentations or marks on the infant's skin.
[US4430088A]
Patent IE-852971-L (IE)
Title: Tricyclic compounds
IPC: C07D498/18
Filed: 1985-11-26
Abstract: This invention relates to tricyclo compounds useful for treatment and prevention of resistance by transplantation, graft-versus-host diseases by medulla ossium transplantation, autoimmune diseases, infectious diseases, and the like, which can be represented by the following formula:to a process for their production, to a pharmaceutical composition containing the same and to a use thereof.
Patent IE-893750-L (IE)
Title: Quinoxaline compounds and their preparation and use
IPC: C07D471/04
Filed: 1989-11-24
Abstract: Heterocyclic dihydroxyquinoxaline compounds having the formula <CHEM>  wherein R<1> is hydroxy, alkoxy, aryloxy, aralkyloxy, cycloalkylalkoxy, cycloalkoxy, or acyloxy; R<5> and R<6> together form a further fused ring, which is substituted with hydrogen, halogen or CN, and R<7> and R<8> independently are hydrogen, NO2, halogen, CN, SO2NR min R min , SO2R min , CF3, or OR min , wherein R min  is hydrogen or C1-4-alkyl; or R<7> and R<8> together form a further fused ring, which is substituted with hydrogen, halogen or CN, and R<5> and R<6> independently are hydrogen, NO2, halogen, CN, SO2NR min R min , SO2R min , CF3, or OR min , wherein R min  is hydrogen or C1-4-alkyl. The invention also relates to a method of preparing the compounds, pharmaceutical compositions thereof, and their use. The compounds are useful in the treatment of indications caused by hyperactivity of the excitatory neurotransmitters, particularly the quisqualate receptors, and especially as neuroleptics.
Patent NO-793421-L (NO)
Inventor: TREIBER HANS JOERG
IPC: C07D267/12
Filed: 1979-10-25
Abstract: PCT No. PCT/EP79/00080 Sec. 371 Date Jun. 26, 1980 Sec. 102(e) Date Jun. 16, 1980 PCT Filed Oct. 22, 1979 PCT Pub. No. WO80/00838 PCT Pub. Date May 1, 1980. The invention relates to novel 1,4-cycloalkano-oxazepines of the general formula  <IMAGE>  where R1 is hydrogen, hydroxyl or alkoxy or acyloxy of 1 to 4 carbon atoms, R2 is a hydrocarbon radical of 1 to 3 carbon atoms, n is 1, 2 or 3 and x is 0 or 1, and of its salts with physiologically acceptable acids; processes for their preparation, and their use in therapy. The novel substances are suitable for the pharmacotherapy of pains of various origins.
Patent NO-794270-L (NO)
Inventor: KOLETAR GABOR ISTVAN
IPC: C07D471/14
Filed: 1979-12-27
Abstract: 1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LU, NL, SE. Imidazo and pyrimido-pyrido-indoles in form of racemates or enantiomers corresponding to formula (I)  see diagramm : EP0015786,P9,F1  wherein n is 1 or 0, R1 is a hydrogen or halogen atom, an alkyl or alkoxy radical or a CF3 group, R2 is an alkyl, cycloalkyl, cycloalkylalkyl, phenyl or benzyl radical, the two latter radicals being optionally substituted with a halogen atom or an alkyl or alkoxygroup, R3 is a hydrogen atom or an alkyl radical, R4 is a hydrogen atom or an alkyl radical, said alkyl and alkoxy radicals having 1 to 4 carbon atoms, with the exception of the compound for which n = 1, R1 = R3 = R4 = H and R2 = CH3 . 1. Claim for the Contracting State : AT A process for preparing imidazo and pyrimido-pyrido-indoles in form of racemates or enantiomers corresponding to formula (I)  see diagramm : EP0015786,P11,F3 wherein n is 1 or 0, R1 is a hydrogen or halogen atom, an alkyl or alkoxy radical or a CF3 group, R2 is an alkyl, cycloalkyl, cycloalkylalkyl, phenyl or benzyl radical, the two latter radicals being optionally substituted with a halogen atom or an alkyl or alkoxy group, R3 is a hydrogen atom or an alkyl radical, R4 is a hydrogen atom or an alkyl radical, said alkyl and alkoxy radicals having 1 to 4 carbon atoms, with the exception of the compound for which n = 1, R1 = R3 = R4 = H and R2 = CH3 , characterized in that a compound of formula (II)  see diagramm : EP0015786,P11,F4  is reacted with an amine R2 NH2 , then the intermediate compound obtained, of formula (III)  see diagramm : EP0015786,P12,F1  is cyclized by means of formaldehyde in 30% aqueous solution, and, when R4 = H, the corresponding compound (I) may be alkylated to yield a compound (I) wherein R4 is alkyl.
Patent NO-800341-L (NO)
Title: Apparat for mating av traad over store avstander
Inventor: SAMOKOVLIISKI DAVID ALBERT
IPC: B65H51/32
Filed: 1980-02-08
Abstract: Apparat for mating av tråd over store av-stander med trådmatemekanisme forbundet over tyristor-trinn med fasekontroll til generatorer for startpulser, og matet med en felles tilførselssamleledning til en hastighetsstabilisator i den første trådmateinnretning, som er forbundet med trådmatemekanismen og med generatoren for startpulsene. Ved en første utførelse er utgangen for generatoren for startpulser i den første trådmateinnretning forbundet ved hjelp av en synkroni-seringssamleledning til inngangene for generatorene for startpulser i den andre og de neste derpå følgende trådmateinnretninger. Ved en andre utførelse er inngangene til generatorene for startpulsene til den andre og de neste derpå følgende innretninger forbundet med utgangene til styringene for synkroniseringspulsene, hvis innganger er forbundet med en av tilførselsmate-ledningene.
Patent NO-840071-L (NO)
Title: Bajonettlaas for en ledning med trykkmedium
Inventor: NIEMI PERTTI KALEVI
IPC: F16L/
Filed: 1984-01-10
Abstract: Bajonettlås for anvendelse ved en trykkmediums-ledning og omfattende et rørformet ytterhus (10), en hendel (1) som er dreibart forbundet med ytterhuset, for dreining av et ventilelement (12), samt koplings-elementer (4,9) som er anordnet ved forenden av ytterhuset og innrettet for løsgjørbar tilkopling av en koplingstapp (11), og som innbefatter en frem- og tilbakeførbar hylse som omslutter ytterhusets for-ende. Det er en ulempe ved bajonettlåser for pneuma-tiske ledninger, at når et lås åpnes, vil utløpsside-trykket strømme med stor kraft ut av en frigjørings-tapp, med den følge at den frakoplete ledningsende kan rykkes ut av hånden og forårsake skade. Denne vanskelighet er løst på den måte at hendelen (1). styrer både ventilelementet (12) for åpning og lukking av en ventil og den frem- og tilbakeførbare hylse (4) for tilkopling og fråkopling av koplingstappen (11), og at ytterhuset (10) er utstyrt, mellom ventilelementet (12) og en koplingstapp-pakning (8), med en kanal (14) som, når ventilen befinner seg i åpen stilling, lukkes av en pakning (6) som er innmontert i den frem- og tilbakeførbare hylse (4) men som, når ventilen befinner seg i lukket stilling og innen den. frem- og tilbakeførbare hylse forskyves til posisjonen for fråkopling av koplingstappen (11), tilbaketrekkes fra stillingen foran kanalen (14) slik at utløpsside-trykket kan avledes til ytterluften.
Patent NO-842350-L (NO)
Inventor: DEWING ERNEST WILLIAM
IPC: C25C3/08
Filed: 1984-06-12
Abstract: The invention concerns cells for production of Al by electrolysis of an alumina-containing electrolyte based on cryolite and having a lining based on alumina for containing the electrolyte. A layer containing an alkali or alkaline earth metal compound, e.g. sodium aluminate, is included in the lining, preferably around the 880 DEG C. isotherm when the cell is in operation. On penetration of the lining by the electrolyte, the compound dissolves in or reacts with the electrolyte so as to raise the solidus and reduce or prevent further penetration.
Patent NO-850377-L (NO)
Inventor: FERGUSON KEITH T
IPC: A61F5/44
Filed: 1985-01-31
Abstract: A closure member for sealing the lower opening end of a drainable ostomy bag having a channel and a tubular member for mating and locking engagement therewith and held in parallel and spaced apart relationship in the open position by a common planar connecting member. The connecting member also serves as a hinge for closing and opening the closure member. Preferably, the channel, tubular member and connecting member are integrally formed in an extrusion process using either a high densitiy polyethylene or high density polypropylene.
Patent NO-855241-L (NO)
Inventor: SUGIMURA YUKIO
IPC: C07F7/18
Filed: 1985-12-23
Abstract: Compounds of formula (I):(wherein R' is carboxy, -CONR<sup>4</sup>R<sup>5</sup>, cyano or hydroxymethyl, and R<sup>2</sup> and R<sup>3 </sup>are hydrogen, alkyl or substituted alkyl, R<sup>4</sup> andR<sup>5</sup> being hydrogen or a variety of groups) have good antibiotic activity and reduced renal toxicity.
Patent NO-873117-L (NO)
Inventor: OTTOW ECKHARD
IPC: A61K31/565
Filed: 1987-07-24
Abstract: 11  beta -(4-isopropenylphenyl)-estra-4,9-dienes of general Formula I <IMAGE>  (I)  wherein X is an oxygen atom or a hydroxyimino grouping N  OH, R1 is a hydrogen atom or a methyl group, R2 is a hydrogen atom or an acyl residue of 1-10 carbon atoms, R3 is a hydrogen atom, the cyanomethyl group, -(CH2)n-, CH2Z, -CH=CH-(CH2)mZ or -C 3BOND C-Y wherein n=0 to 5 and m=1 to 4, Z meaning a hydrogen atom or the OR4 group with R4 meaning a hydrogen atom, an alkyl or alkanoyl group each of 1-4 carbon atoms, and Y meaning a hydrogen, chlorine, fluorine, iodine or bromine atom, an alkyl, hydroxyalkyl, alkoxyalkyl or acyloxyalkyl group each of 1-4 carbon atoms in the alkyl or acyl residue, possess antiprogestational activity.
Patent NO-890941-L (NO)
Inventor: WAGERS KEVIN J
IPC: B29C48/08
Filed: 1989-03-06
Abstract: A method and apparatus for producing a plastic film having strips of an adhering material embedded in each surface of the film, which film may have an anti-blocking agent incorporated therein, and a composite plastic film so produced is provided which includes initially providing a first stream of heat plastified extrudable thermoplastic film material to a cast film die. The cast film die has two opposing die lips with each die lip having a plurality of spaced strip channels. The strip channels of one die lip are laterally offset from the strip channels of the second die lip. A heat plastified extrudable adhering material is introduced into the plastified film material from the strip channels and then the composite body of materials is forced from the die lips of the cast film die and cooled to form the plastic film.
Patent NO-900255-L (NO)
Title: Peptider med t-cellehjelperaktivitet.
Inventor: HEAVNER GEORGE
IPC: C07K5/10
Filed: 1990-01-18
Abstract: Tetrapeptlder og pentapeptlder som har den tlologlske aktiviteten til det humane molekylet thysplenln. Det blir også frembrakt farmasøytiske sammensetninger som inneholder peptidene og fremgangsmåter til anvendelse derav.
Patent NO-902154-L (NO)
Inventor: MCCLUHAN THOMAS K
IPC: C21C1/02
Filed: 1990-05-15
Abstract: A desulphurisation agent for molten iron is made up of commercial calcium carbide, a flux agent comprising calcium aluminate slag or silicon dioxide, and a metal oxide. The metal oxides may be an iron oxide and/or manganese oxide.
Patent NO-903149-L (NO)
Inventor: REUTELINGSPERGER CHRISTIAAN
IPC: C07K14/005
Filed: 1990-07-13
Abstract: The present invention relates to processes for purifying annexines. The overall process includes the steps of preparing a homogenized cell preparation and adjusting the pH to about 8.0 to 10.0, adding at least one bivalent cation, adding a phospholipid, washing the insoluble cell residue to remove the soluble constituents, and extracting the annexines from the cell residue with a chelating agent. This process initially promotes the adsorption of the annexines onto the insoluble cell residue or membrane of the host organism. The adsorption step makes it possible to eliminate unwanted soluble matter from the homogenized material by simple washing. Desorption is accomplished by using a chelating agent.
Patent NO-912340-L (NO)
Title: Fremgangsmaate for fremstilling av inhibitorer av hiv-revers transkiptase.
Inventor: HOFFMANN JR JACOB M
IPC: C07D405/12
Filed: 1991-06-17
Abstract: Forbindelser som har formelen 4 l /-^ X-(CH)n-\J hvori RO O OR X er NR, O, S, CH , S, S0_, C, CH , OH CH-CH, CH-C, RC=CR, NCR, NCH-CO.R, ^ ^ n n ^- *- o o NS, NSO_ eller NC, hvori R er H, C, ¿- 11' i J-~° R R R alkyl, C, g-alkenyl eller C3_g-cyklo- alkyl; Z er O, S eller NR når R er H eller C,fi-alkyl, n er 0-4; R,, R- og R. er like eller forskjellige og er forskjellige substituenter/ er aryl eller en heterocyklisk gruppe.
Patent NO-914375-L (NO)
Inventor: NEGI SHIGETO
IPC: C07D501/06
Filed: 1991-11-08
Abstract: A compound represented by the following formula (1a): a process for the preparation thereof, an antibacterial composition comprising the same and the use thereof for the preparation of a medicament and for the synthesis of related cephem compounds.
Patent NO-921794-L (NO)
Inventor: GILHOUSEN KLEIN S
IPC: H04B7/26
Filed: 1992-05-06
Abstract: A spread spectrum receiver subsystem for utilization in a CDMA cellular telephone having a searcher receiver for scanning the time domain so as to use the PN processing gain and time discrimination properties of spread spectrum coding to determine the location in the time domain and the received signal strength of multiple receptions of a pilot signal traveling upon one or more physical propagation paths to reception. The searcher receiver provides a control signal indicative of the received pilot signals of greatest strength and corresponding time relationship. A data receiver receives spread spectrum communication signals accompanying each received pilot signal and is responsive to the searcher control signal for acquiring and demodulating a spread spectrum communication signal, concomitant with the pilot signal of greatest signal strength, and thus providing a corresponding information bearing encoded output signal.
Patent NO-922135-L (NO)
Inventor: ESCHER CLAUS
IPC: C09K/
Filed: 1992-05-29
Abstract: A ferroelectric liquid crystal mixture containing two or more components, at least one of which is a complex ligand for ions, in particular for cations, is particularly suitable for use in ferroelectric liquid crystal displays.
Patent NO-923860-L (NO)
Inventor: CHERRY FRANK MICHAEL
IPC: H04J3/06
Filed: 1992-10-02
Abstract: A communication system in which a plurality of nodes or terminal access units 2 are connected via a media ring 3. Data is transmitted in a series of data packets within which the bits or bytes are multiplexed. To ensure line availability and avoid contention and delay each access unit has preassigned channels within the packet. <IMAGE>
Patent NO-925034-L (NO)
Inventor: SAGE JEAN-MARC
IPC: C08L77/10
Filed: 1992-12-29
Abstract: A process for the manufacture of polyamides consisting essentially of the stages of: (i) reacting 10 to 90% by weight of the aliphatic and/or cycloaliphatic and/or aromatic-aliphatic diamines (c) with a lactam and/or corresponding amino acid (a) or the substantially stoichiometric combination of one or more aliphatic diamine(s) and of one or more dicarboxylic aliphatic acid(s) and with the aromatic diacid (b); and (ii) reacting the remainder of the aliphatic and/or cycloaliphatic and/or aromatic-aliphatic diamine (c) with the oligomer produced in stage (i) in one or more substages.
Patent NO-932923-L (NO)
Title: Selvborende strekk-blindnagle
Inventor: GASSER DANIEL
IPC: F16B2/00
Filed: 1993-08-17
Abstract: Selvborende strekk-blindnagle, bestående av en naglehylse (1) med en anslagsflens (6) samt et nagleskaft (2) hvor det i den ene ende er anordnet eller utformet en bordel (3) og i det annet endeparti utformet minst en avflatning (7) for fastgjcr- ing av et dreie- og trekkverktøy for innboring og fastsetting av strekk-blindnaglen. Festeseksjonen (4) er forsynt med minst en avflatning (7) som urgår fra trekkskaftets (2) frie ende og strekker seg over den storste del av lengden av det fritt utkragede parti over naglehylsen (1). Ihvertfall på et delparti av festeseksjonen (4) er det anordnet tverribber (8) for bedre fastgjoring av verktøyet ved innsetting av strekk- blindnaglen og med overforing av strekkrefter.
Patent NO-933842-L (NO)
Inventor: DIONNE KEITH E
IPC: A61K48/00
Filed: 1993-10-25
Abstract: An immunoisolatory vehicle for the implantation into an individual of cells which produce a needed product or provide a needed metabolic function. The vehicle is comprised of a core region containing isolated cells and materials sufficient to maintain the cells, and a permselective, biocompatible, peripheral region free of the isolated cells, which immunoisolates the core yet provides for the delivery of the secreted product or metabolic function to the individual. The vehicle is particularly well-suited to delivery of insulin from immunoisolated islets of Langerhans, and can also be used advantageously for delivery of high molecular weight products, such as products larger than IgG. A method of making a biocompatible, immunoisolatory implantable vehicle, consisting in a first embodiment of a coextrusion process, and in a second embodiment of a stepwise process. A method for isolating cells within a biocompatible, immunoisolatory implantable vehicle, which protects the isolated cells from attack by the immune system of an individual in whom the vehicle is implanted. A method of providing a needed biological product or metabolic function to an individual, comprising implanting into the individual an immunoisolatory vehicle containing isolated cells which produce the product or provide the metabolic function.