baber/WOPTO huggingface dataset:
Patent CA-2369711-A1 (CA)
IPC: A61P31/14
Filed: 2002-01-30
Abstract: The present invention covers macrocyclic compounds of formula I active in-vitro and in cellular assays against the NS3 protease of the hepatitis C virus. (See formula I) wherein W is CH or N; R21 is H, halo, C1-6 alkyl, cycloalkyl, haloalkyl, C1-6 alkoxy, cycloalkoxy, hydroxy, or N(R23)2, wherein each R23 is independently H, C1-6 alkyl or cycloalkoxy; and R22 is H, halo, C1-6 alkyl, C3-6 cycloalkyl, C1-6 haloalkyl, C1-6 thioalkyl, C1-6 alkoxy, C3-6 cycloalkoxy, C2-7 alkoxyalkyl, C3-6 cycloalkyl, C6 or 10 aryl or Het, wherein Het is a five-, six-, or seven-membered saturated or unsaturated heterocycle containing from one to four heteroatoms selected from nitrogen, oxygen and sulfur; said cycloalkyl;  aryl or Het being substituted with R24, wherein R24 is H, C1-6 alkyl, C3-6 cycloalkyl, C1-6 alkoxy, C3-6 cycloalkoxy, NO2, N(R25)2, NH-C(O)-R25; or NH-C(O)-NH-R25, wherein each R25 is independently: H, C1-6 alkyl or C3-6 cycloalkyl; or R24 is NH-C(O)-OR26 wherein R26 is C3-6 alkyl or C3-6 cycloalkyl; R3 is hydroxy, NH2, or a group of formula -NH-R31, wherein R31 is C3-6 to aryl, heteroaryl, -C(O)-R32, -C(O)-OR32 or -C(O)-NHR32, wherein R32 is: C1-6 alkyl or C3-6 cycloalkyl; D is a 5 to 10-atom saturated or unsaturated alkylene chain optionally containing one to three heteroatoms independently selected from: O; S, or N-R41, wherein R41 is H, C1-6 alkyl, cycloalkyl or -C(O)-R42, wherein R42 is C1-6 alkyl, cycloalkyl or C6 or 10 aryl; R4 is H or from one to three substituents at any carbon atom of said chain D, said substituent independently selected from the group consisting of C1-6 alkyl, C1-6 haloalkyl; C1-6 alkoxy, hydroxy, halo, amino, oxo, thio or C1-6 thioalkyl, and A is an amide of formula -C(O)-NH-R5, wherein R5 is selected from the group consisting of: C1-8 alkyl, C3-6 cycloalkyl, C6 or 10 aryl or C7-16 aralkyl; or A is a carboxylic acid or a pharmaceutically acceptable salt or ester thereof.
Patent CA-2370012-A1 (CA)
Title: Muffler heat exchanger
Inventor: CROMBEEN PETER F
IPC: F01N3/32
Filed: 2002-01-02
Abstract: A muffler heat exchanger for an engine, the heat exchanger having a body installed in a muffler, having at least one inlet for the exhaust gas from the engine on the body, a baffled chamber in the body to receive exhaust gas from the at least one exhaust gas inlet, at least one exhaust gas outlet from the baffled chamber to vent the exhaust gas from the baffled chamber, at least one fresh-air inlet on the body, a heat exchange conduit extending into the baffled chamber between the fresh air inlet and the at least one exhaust gas outlet, the heat exchange conduit being sized and shaped to permit heat exchange between the fresh air and the exhaust gas in the baffled chamber, and a fresh air outlet on the heat exchange conduit, the fresh air outlet being sized, shaped and located relative to the exhaust gas outlet to permit the fresh air to mix with exhaust gases being vented from the baffled chamber to lower an exit temperature of the exhaust gases.
Patent CA-2370029-A1 (CA)
Title: Polycarbonate composition having reduced tendency to splay
Inventor: PISIPATI RAMESH M
IPC: C08K5/00
Filed: 2000-04-10
Abstract: A transparent thermoplastic molding composition having good release properties is disclosed. The composition which contains no magnetic elements contains a polycarbonate resin and 0.01 to 0.3 percent by weight of a mold release agent.  The agent is the product of a reaction of a compound represented by formula (I), where R1 denotes a C1-30-alkyl group, with at least one member selected from the group consisting of (i), where R2 and R3 independently denote C1-30-alkyl or an aryl group, and (ii), where n is 1-7.
Patent CA-2370918-A1 (CA)
Title: Up-hole pump-in core barrel apparatus
Inventor: MARSHALL JOHN C
IPC: E21B25/02
Filed: 2002-02-06
Abstract: The drilling apparatus includes a wire line core barrel head assembly having a latch body seatable on a drill string landing shoulder and retainable in a latch seated position by a latch assembly spring urged to a latch seated position, fluid seals on the latch body to facilitate fluidly propelling the head assembly in an upward direction, valve mechanism in a latch body bypass channel to restrict fluid flow therethrough to provide a signal of the latch body seating on the landing shoulder and then opening together with being retractable to an open position by a latch retractor prior to the latch body being retracted and second valve mechanism to block axial outward flow in the bypass channel. The fluid seals are mounted to a latch body adaptor that may be removed to convert from an up-hole to a down-hole assembly.
Patent CA-2371042-A1 (CA)
Title: Cultured cells of ficus stipulata thunb. (=ficus thunbergii) and a method for culturing tissues of the ficus stipulata thunb. by using said cultured cells
Inventor: MORIKAWA HIROMICHI
IPC: C12N5/04
Filed: 2002-02-06
Abstract: A cultured cell of Ficus stipulata Thunb. having high differentiating power, said cultured cell being obtained by culturing a part of a tissue of the Ficus stipulata Thunb. in a culture medium containing at least one kind of thidiazuron and benzyladenine in an amount effective to induce callus formation of the Ficus stipulata Thunb.
Patent CA-2371254-A1 (CA)
Inventor: DUNCAN GARY L
IPC: B60N2/28
Filed: 2002-02-14
Abstract: A bench-type dinette seat frame includes a pair of spaced-apart anchor bars positioned at the junction of a seat section and a back section of the dinette frame and a third attachment point positioned above and intermediate the first and second spaced apart anchors to provide a three-point attachment of a child safety seat to the dinette frame.
Patent CA-2373094-A1 (CA)
Title: Stainless steel canister for propellant-driven metering aerosols
Inventor: LOSTRITTO RICHARD THOMAS
IPC: C22C38/42
Filed: 2000-05-24
Abstract: The present invention relates to corrosion resistant stainless steel canisters for propellant-containing aerosol formulations for use in propellant gas-operated inhalers.
Patent CA-2374831-A1 (CA)
Title: Imprimante interactive
Inventor: SILVERBROOK KIA
IPC: G06F3/033
Filed: 2000-05-24
Abstract: Cette imprimante est destinée à imprimer une seconde interface sur une seconde surface, en réponse à des premières données d'indication reçues à partir d'un dispositif capteur se présentant sous la forme d'un pointeur optique. Les premières données d'indication sont détectées par le pointeur optique à partir de premières données codées, une première interface étant disposée sur une première surface et comprenant ces premières données codées. L'imprimante comprend un module d'entrée et un module d'impression. Le module d'entrée est conçu pour recevoir les premières données à partir du pointeur optique, ces premières données indiquant au moins partiellement des données de réponse. Le module d'entrée produit des secondes données d'indication, en fonction des premières, les secondes indiquant au moins partiellement les données de réponse. Les secondes données d'indication sont envoyées à un système informatique. Le module d'impression comporte un mécanisme d'impression conçu pour recevoir les données de réponse à partir du système informatique. La seconde interface est basée, au moins partiellement, sur les données de réponse. Le module d'impression imprime alors la seconde interface sur la seconde surface, à l'aide du mécanisme d'impression.
Patent CA-2375050-A1 (CA)
Title: Compositions t-bet et methodes d'utilisation de ces compositions
Inventor: GLIMCHER LAURIE H
IPC: A01K67/027
Filed: 2000-06-01
Abstract: L'invention concerne des molécules d'acide nucléique codant T-bet et des protéines T-bet isolées. Elle concerne également des molécules d'acide nucléique antisens, des vecteurs d'expression recombinants contenant une molécule d'acide nucléique de l'invention, des cellules hôtes dans lesquelles ces vecteurs d'expression ont été introduits, et des animaux transgéniques non humaines porteurs du transgène T-bet. L'invention concerne en outre des protéines de fusion T-bet et des anticorps anti-T-bet, ainsi que des méthodes d'utilisation des compositions T-bet, notamment des méthodes de détection de l'activité de T-bet dans un échantillon biologique, des méthodes de modulation de l'activité de T-bet dans une cellule, et des méthodes d'identification d'agents modulant l'activité de T-bet.
Patent CA-2375758-A1 (CA)
Inventor: BOLLEN NIELS
IPC: B62B3/00
Filed: 2002-03-06
Abstract: A carriage is provided with castors, a power driven wheel at one end of t he carriage, a support element supporting the wheel and a raising and lowering mechanism for raising the support element and thus the wheel out of engageme nt with the ground and for lowering the support element and thus the wheel into engagement with the ground. The support element is angularly displaceable about a vertical axis to turn the wheel to steer the carriage when the power driven wheel is in engagement with the ground. A locking device is also provided for releasably locking a castor at the other end of the carriage in a position in which it will encourage the carriage to move in a straight ahead direction when the power driven wheel is in engagement with the ground. The carriage may be in the form of a n invalid hoist, shopping trolley or bed.
Patent CA-2378594-A1 (CA)
Title: Percutaneous catheter and guidewire for filtering during ablation of myocardial or vascular tissue
Inventor: ROOT JONATHAN D
IPC: A61B18/24
Filed: 2000-08-03
Abstract: An ablation catheter system for capturing and removing necrotic tissue and thrombi generated during an ablative procedure is disclosed. The catheter typically includes an elongate member, a filtration assembly disposed within  the distal region, and an ablation instrument at the distal end. Alternatively, the ablation instrument is carried on the distal end of an ablation catheter, which is disposed within a lumen of the catheter system. The catheter may further include an aspiration port and lumen. Methods of using the devices in preventing distal embolization during ablative procedur e are disclosed.
Patent CA-2378626-A1 (CA)
Inventor: SOLIMAN SAMIR S
IPC: H04W84/04
Filed: 2000-07-19
Abstract: A method and apparatus for sequentially synchronized timing and frequency generation in a communication network includes a parent station (12) for maintaining system time and frequency values, a time/frequency transfer unit  (13a, 13b, 13c) for receiving and demodulating the system time and frequency  values from the parent station (12) and generating corrected system time and  frequency values by adjusting a clock and the center frequency of a pilot signal at a child station (16a, 16b) to remove time and frequency discrepancies, and a child station (16a, 16b) to which the time/frequency transfer unit directly communicates the corrected system time and frequency values. The child station (16a, 16b) become a parent station (12) upon communication of the corrected system time and frequency values. The sequenc e may be repeated for as many stations as are deployed in the network.
Patent CA-2380236-A1 (CA)
Title: Safety stirrup
Inventor: BOSTOCK HAYDEN
IPC: B68C3/02
Filed: 2000-07-20
Abstract: A safety stirrup suitable for horse riding, the safety stirrup including a generally U-shaped mounting member (5) and a foot support member for receiving a rider's foot (10), such that when the rider's foot is in the normal use position the foot support is restrained by at least one mounting, and wherein vertical movement of the rider's foot out of the normal use position causes the mounting to release the foot support (10) sufficiently that the foot support (10) can move in the same direction as the rider's foot until the foot support (10) is fully disconnected from the U-shaped mounting member (5).
Patent CA-2381070-A1 (CA)
Title: Detector of chemical substances and concentration-measuring method of chemical substances
Inventor: DANNO MINORU
IPC: H01J49/40
Filed: 2001-06-13
Abstract: A vacuum ultraviolet ray generating unit (5) which generates vacuum ultraviolet rays used for ionizing a sample gas Gs in an ionization chamber (1) and a mass spectrometry unit (6) which accelerates the sample gas Gsi ionized by vacuum ultraviolet rays so as to measure the flight time of the accelerated substance.
Patent CA-2384977-A1 (CA)
Title: Resonant optical cavities for high-sensitivity, high-throughput biological sensors and methods
Inventor: BLAIR STEVEN M
IPC: G01N21/27
Filed: 2000-10-12
Abstract: Biosensors including resonant optical cavities. The resonant optical cavities are shaped so as to generate whispering gallery modes, which increase the quality factors of the cavities and facilitate the detection of analytes in a sample with enhanced sensitivity. The sizes of the resonant optical cavities facilitate their use in biosensors that include arrays of sensing zones.  Accordingly, the resonant optical cavities may be used in high-density sensing arrays that can be read in real-time and in parallel. Thus, the resonant optical cavities are useful for detecting small concentrations of samples in real-time and with high throughput. Different embodiments of the biosensors are also disclosed, as are methods for using the biosensors.
Patent CA-2385149-A1 (CA)
Inventor: SUEYOSHI MASAHIRO
IPC: G10L19/14
Filed: 2001-08-23
Abstract: A signal transmission apparatus is provided for transmitting a plurality of pieces of encoded audio information en-coded by the same encoding method via a digital interface to a signal reception apparatus, in which each of the plurality of pieces of encoded audio information has a sampling frequency of F or 1/2 × F. The apparatus comprises a data generating section for, based on one-frame data obtained by dividing the encoded audio information into frames, generating at least one block, and a data output section for outputting the at least one block generated by the data generating section to the digital interface. Each of the at least one block includes a body portion, and a header portion storing management information for managing data stored in the body portion.
Patent CA-2386426-A1 (CA)
Title: Elements logiques magnetiques
Inventor: COWBURN RUSSELL
IPC: H03K19/168
Filed: 2000-10-11
Abstract: A logic device formed from at least one chain of dots of magnetic material. Each dot has a width of 200 nm or less and is spaced at a distance that is sufficiently small to ensure magnetic interaction of adjacent dots.
Patent CA-2386902-A1 (CA)
Title: Seamed sleeved blanket and method for making and using same
Inventor: BYERS JOSEPH L
IPC: B41F7/02
Filed: 2000-10-13
Abstract: The design, production and use of a seamed cylindrical offset printing blanket. Conventional, manufactured blanket material (42) in roll or flat form by methods well known in the art is adhered to a sleeve to economically produce a blanket. The ends (62, 64) of the flat material are joined in close proximity such that the resulting seam or gap (45), from a printing standpoint, is negligibly small. The joint is made with a resilient compound that fills the remaining seam or gap resulting in a useful sleeved blanket. In use, the joint is aligned with non-print areas on the plate cylinder or the opposing plate gap. Since the seam (45) is narrower than the plate gap, no loss of print length results from the seam.
Patent CA-2387177-A1 (CA)
Title: Medical needle assemblies
Inventor: SWENSON JON D
IPC: A61M5/00
Filed: 2002-05-21
Abstract: A shielded, sterile, single-use unit dose needle assembly includes a unit dose needle with a hub and two packaging shields sealingly mated to one another encasing the hub and unit dose needle. The unit dose needle has a handle end and a patient end configured to hold a unit dose of a vaccine. The hub is fixedly attached to the unit dose needle between the handle end and the patient end. The first packaging shield extends over the patient end, and the second packaging shield extends over the handle end of the unit dose needle. The first and second packaging shields are removably attached to one another to form an air-tight sterility seal, with the unit dose needle contained within the first packaging shield.
Patent CA-2387551-A1 (CA)
Inventor: CASSESE PHILIPPE
IPC: B27F7/02
Filed: 2000-10-10
Abstract: The inventive machine comprises two independent fastening stations. The first station (2), which is used for separately, successively assembling the corners of the frame, is provided with two cutting heads (3, 7) for cutting the mouldings (5, 9) that form the corner of the frame and a fastening head (11) and devices with stops (6, 10) and grips (14) for holding the mouldings. The second station (15), which is used for the final assembly of the frame, is provided with two fastening heads (19, 20) installed opposite each other according to the diagonal of the frame being produced. The invention is suitable for use in framing.
Patent CA-2388046-A1 (CA)
Title: Material systems and methods of three-dimensional printing
Inventor: DICOLOGERO MATTHEW
IPC: B29C67/00
Filed: 2000-11-03
Abstract: The present invention is directed to three-dimensional printing material systems and method, and an article made therefrom. The method of the present invention includes building cross-sectional portions of a three-dimensional article, and assembling the individual cross-sectional areas in a layer-wise fashion to form a final article. The individual cross-sectional areas are built by using an ink-jet printhead to deliver a fluid to a particulate material.
Patent CA-2388678-A1 (CA)
Inventor: MEYERS GREGOR
IPC: A61P31/12
Filed: 2000-11-29
Abstract: Cette invention a trait à l'utilisation de virus actifs de la diarrhée virale bovine (BVD), atténués de manière spécifique, aux fins de la préparation d'un vaccin utilisable dans le cadre de la prévention et/ou du traitement d'infections dues à la diarrhée virale bovine d'animaux ou de bovins reproducteurs, de vaches pleines ainsi que dans le cadre de la protection du foetus chez les vaches pleines.
Patent CA-2389567-A1 (CA)
Inventor: FRASER STUART A
IPC: G06Q30/06
Filed: 2000-11-15
Abstract: Published without an
Patent CA-2390345-A1 (CA)
Inventor: HUGHES WILLIAM JAMES
IPC: E21B17/00
Filed: 2002-06-11
Abstract: The invention comprises a section of improved tubing with coupled end connectors and an insert containing at least one electrical wire. The insert has an outside diameter that is approximately equal to the inside diameter of the improved tubing. The insert also has projections at each end such that when two inserts are placed end to end, the projections will mate up. The insert has at least one groove cut into its side and running the length of the insert. The groove is for the placement of a wire for transmission of power to the well bore or for the placement of a wire for transmission of data from the well bore. The groove is installed down the length of the insert. The groove is deep enough so that when a wire is placed inside the groove, the wire does not project beyond the outside diameter of the insert. The insert may contain as many groove and wire combinations as are necessary for the particular application. The wire has an electrical connection at each end of the insert. When the inserts are placed end to end, the insert projections line up the electrical connectors and correct mating of the insert projections will result in correct mating of the electrical connectors. The inserts are the same length as the tubing and are installed inside the tubing such that the insert is flush with the first end of the tubing. The inserts are then welded to the tubing or secured to the tubing by some other method. A threaded coupler is then installed on the second end of the tubing to protect the exposed insert and electrical connector. The coupler will also be used to secure the improved tubing together. Individual pieces of improved tubing are connected together in a three step process. First the coupler is threaded onto the second end of the tubing. Next, the first end of one tubing member is positioned above the second end of another tubing member. Next, the insert projections are properly aligned so that they will mate together. Then, the two pieces of tubing are plugged together so that the electrical connections engage each other. Finally, the coupler is screwed onto the first end of the tubing so that the two pieces of tubing are secured together. The process may be repeated as necessary to create an elongated string of improved tubing.
Patent CA-2393778-A1 (CA)
Title: Surface printing inks and coatings for use on flexible film or paper packages
Inventor: DAVIDS MICHAEL A
IPC: C09D11/02
Filed: 2000-12-07
Abstract: This invention relates to non-aqueous coating and ink formulations for use on flexible film or paper packages re-quiring aseptic packaging conditions. The coating formulation comprises: 1) a mixing varnish comprising a phenolic-modified co-solvent-type polyamide resin, 2) a nitrocellulose compound varnish, 3) a non-aqueous solvent mixture, and 4) specialty additives, and wherein all components present in the formulation are stable in the presence of an oxidizing agent. The ink formulation addi-tionally requires a pigment and a non-aqueous solution of a metal salt of propionic acid. The printed and coated packaging materials, and methods of aseptic packaging, as well as the aseptic packages are also disclosed.
Patent CA-2394283-A1 (CA)
Title: Arrangement and method for forming a multilayered paper or paperboard web
Inventor: KINNUNEN JUKKA
IPC: D21F9/02
Filed: 2000-12-15
Abstract: The invention relates to an arrangement for forming a multilayered paper or paperboard web (D) from stock suspen-sions with papermaking fibres and fines, said arrangement including at least a first (101; 201; 301; 401; 501) and a second (102; 202;  302; 402; 502) forming unit, at least one of the forming units being of twin wire type and having a forming roll for forming a fibrous web (A or B) having a higher content of fines at one side (x or z) than at the other (y or w), and a couch device (117; 217; 316; 317;  416, 417) for couching together said fibrous web (A or B) having a higher content of fines at one side with an other fibrous web (B  or A) to form the multilayered web (D), wherein both of the two forming units are of twin wire type and include a forming roll (109;  209; 309; 409; 509 and 111; 211; 311; 411; 511) for forming a fibrous web (A  and B) having a higher content of fines at one side (x and z) than at the other (y and w), and that the two forming units (101;  201; 301; 401; 501 and 102, 202; 302; 402; 502) are so arranged relative to each other as to place the web sides (x and z) having the highest content of fines in contact with each other for couching together to form the multilayered web (D). The invention further relates to a method of forming a multilayered paper or paperboard web using said arrangement.
Patent CA-2394393-A1 (CA)
Inventor: TOKUDA MASAAKI
IPC: A61K31/616
Filed: 2000-12-15
Abstract: Remedies for external use for allergic skin diseases containing aspirin alone, which exerts an excellent therapeutic effect on allergic skin diseases with little side effects, as the active ingredient; and a method of treating allergic skin diseases by using these agents for external use.
Patent CA-2395262-A1 (CA)
Inventor: MATTEJAT ARNO
IPC: H01M8/04223
Filed: 2000-12-22
Abstract: L'invention concerne la dynamique système d'un système de piles à combustible fournissant l'énergie pour une unité d'entraînement d'un véhicule automobile. Le système selon l'invention fournit la moitié de sa puissance maximale en moins de cinq minutes après une période de repos pouvant aller jusqu'à trois semaines.
Patent CA-2396351-A1 (CA)
Inventor: MARQUIS KAREN LOVELL
IPC: A61K31/551
Filed: 2000-12-07
Abstract: Therapeutic combinations useful in the treatment or prevention of psychotic disorders, to pharmaceutical compositions containing said combinations, and to their use in the treatment or prophylaxis of prevention disorders are provid ed.