baber/WOPTO huggingface dataset:
Patent WO-2015024022-A9 (WO)
Inventor: MILLER BENJAMIN L
IPC: A61K39/395
Filed: 2014-08-18
Abstract: Selon certains aspects, la présente invention concerne un agent perturbant de façon transitoire la claudine-1 dans des jonctions serrées. L'agent comprend un peptide ayant au moins 40 % de résidus d'acides aminés polaires non chargés et une structure secondaire en feuille β auto-assemblée. Selon certains aspects, la présente invention concerne également des formulations médicamenteuses et de vaccins transépithéliales, ainsi que des peptides isolés, des compositions pharmaceutiques et des dispositifs d'administration transdermique. L'invention concerne en outre des procédés de perturbation de barrière épithéliale et des procédés d'administration des formulations transépithéliales.
Patent WO-2017003734-A9 (WO)
Title: Procédé d'activation de matériaux en deux dimensions pour des électrodes de batterie d'intercalation d'ions multivalents/polyatomiques
Inventor: YAO YAN
IPC: H01M4/139
Filed: 2016-06-20
Abstract: L'invention concerne un procédé pour activer des matériaux hôtes en deux dimensions pour une batterie à ions polyatomiques/multivalents qui peut comprendre l'ajout d'un sel de formation de piliers dans l'électrolyte. Ce procédé peut être suivi par l'intercalation électrochimique in situ des ions de formation de piliers, de molécules de solvant et d'ions multivalents dans l'espace de van der Waals de matériaux hôtes. Après le processus d'activation, le matériau hôte est transformé en un matériau 2D expansé intermédiaire ayant une capacité spécifique et des performances de débit considérablement améliorées pour des ions multivalents d'intercalation.
Patent WO-2018089057-A9 (WO)
Title: Surveillance et commande installées d'une turbine à gaz pour empêcher la résonance dynamique des ondes stationnaires
Inventor: GRAHAM EDWARD
IPC: F01D25/04
Filed: 2017-07-13
Abstract: L'invention concerne un procédé de prévention d'ondes stationnaires dans une turbine à gaz installée ayant un ventilateur ayant une vitesse de ventilateur et un compresseur ayant une vitesse de compresseur, consistant à corriger les vitesses de ventilateur et de compresseur en ce qui concerne la température et à surveiller les vitesses corrigées pour empêcher celles-ci de converger ou de devenir identiques. De plus, un programme de surveillance et d'ajustement mis en œuvre par ordinateur peut surveiller une position d'un aéronef sur un graphique ACTFS et effectuer des ajustements pour éviter d'intercepter une ligne de surtension en changeant la vitesse de l'avion, la vitesse du ventilateur et/ou du compresseur ou en changeant l'altitude. Un aéronef peut former une onde stationnaire lors d'un croisement ou d'un fonctionnement sur une ligne de surtension d'un graphique ACTFS, et cette condition doit être évitée, ce qui peut nécessiter une logique de surveillance et de commande de débit de données élevé.
Patent WO-2020036656-A9 (WO)
Title: Inhibition of lipofuscin aggregation by molecular tweezers
Inventor: BITAN GAL
IPC: G01N3/04
Filed: 2019-04-25
Abstract: In various embodiments methods for the treatment and/or prophylaxis of lipofuscin-related disorders are provided. In certain embodiments the methods involve administration of an effective amount of a molecular tweezers to a subject in need thereof.
Patent WO-2020028853-A9 (WO)
Inventor: CARNEGIE GRAHAM ALEXANDER
IPC: E21B19/087
Filed: 2019-08-02
Abstract: An end effector (400) for a robotic arm, the end effector (400) comprising: two pipe engaging jaws (404), each jaw comprising an inner contour configured for engaging a pipe section, wherein at least one jaw (404) is a fixed jaw; wherein the end effector (400) is configured to restrict radial movement of the pipe section while permitting axial movement.
Patent WO-2020163496-A9 (WO)
Inventor: PAYTAVI REGIS
IPC: G01N33/53
Filed: 2020-02-05
Abstract: For enhanced selection of efficient targeted genome manipulating agents (310), an apparatus (102) includes first and second chip-based biosensors (104a, 104b) having one or more sensing surfaces (308a) configured to detect biomolecular binding interactions between a nucleic acid sample (306) and a targeted genome manipulating agent (310) functionalized to a capture surface (126) within a sensing range (328) of a sensing surface (308a). The first chip-based biosensor (104a) uses a nucleic acid sample (306) incubated with a blocking agent (318) and the second chip-based biosensor (104b) holds a nucleic acid sample (306) that omits the blocking agent (318). A measurement apparatus (102) measures first and second sets of response signals (342a, 342b) indicative of the respective biomolecular binding interactions. An analysis module (116) determines the genome manipulating efficiency parameters of the targeted genome manipulating agent (310). A system (100) and a method (300) perform the functions of the apparatus (102).
Patent WO-2021236585-A9 (WO)
Inventor: BALLARD JASON
IPC: B64G1/16
Filed: 2021-05-18
Abstract: An apparatus, system and method are provided for launching, deploying and moving mobility platforms used to produce a three-dimensional product using additive printing. The product, or object, is made by collecting materials in-situ at an off-Earth celestial body. A sintering apparatus, such as a laser, is used to consolidate the planetary regrowth into a solid object. The apparatus can receive power, and can apply heat to assist in the consolidation process. The apparatus is moveable to the build site, and includes a print head having a collector for receiving collected materials, a conditioner for sintering and heating the collected materials, and an extruder, specifically a slip form opening in which the materials can be dispersed over the surface of the extraterrestrial body where the powder form of the conditioned materials are sintered, fused, or consolidated into a hard solid bead of material.
Patent WO-2023211969-A9 (WO)
Inventor: CHEN TYLER
IPC: G01S7/41
Filed: 2023-04-25
Abstract: Machine learning for optically identifying user motions is provided. An optical path is formed as light travels through a portion of the user's body and is sampled by optical sensors to form a set of signals which vary as a function of the user's tissue configuration in the optical path. These signals are preprocessed at least by suppressing signal baselines in real-time during operation, which allows for improved low-latency detection of user motions via a trained statistical model which is more robust to variability in optical paths and tissue configuration.
Patent CS-253628-B1 (CS)
Inventor: MARA JIRI
IPC: B27L1/00
Filed: 1986-02-07
Abstract: Zařízení pro posuv pracovního orgánu,
zejména u lesnických odvětvovacích a krátících
strojů umožňující zvětšení délky
posuvu nebo síly použitého přímočarého
motoru. Toto je umožněno zařízením sestávajícího
z ozubeného kompaktního trojkola
otočně uloženého v unašeči spojeným s
pístnici přímočarého motoru, které je svými
postranními koly shodného poloměru
v záběru s pevnými ozubenými tyčemi spojenými
s rámem stroje a střední ozubené
kolo tohoto trojkola v záběru s pohybovou
ozubenou tyčí, na kterou je napojen pracovní
orgán.
Patent DK-168476-B1 (DK)
Inventor: STUMPF FRIEDRICH
IPC: B65D33/38
Filed: 1989-01-18
Granted: 1994-04-05
Abstract: A bag for containing liquid products, for example, is made of a heat-weldable sheet material. The sheet material may suitably be a compound sheet material which provides a rear face, a front face and an insert bottom. Disposed at an upper portion of the front or rear face is a threaded closure comprising a screw-threaded pipe socket and a screw cap. The pipe socket penetrates one face of the bag and is bonded to the interior surface of the bag with the aid of a welding flange having a larger diameter. The welding flange has a chamfered outer rim cooperating with the sheet material to form a V-shaped circumferential groove which is at least partially filled with the molten plastic material of the sheet during the welding operation. The threaded closure permits the bag to be repeatedly opened and closed for piecemeal dispensing its contents.
Patent HU-220671-B1 (HU)
Title: 6- or 7-(2-imino-2-imidazolidine)-1,4-benzoxazines and pharmaceutical compositions containing them
Inventor: GLUCHOWSKI CHARLES
IPC: C07D413/12
Filed: 1991-09-10
Abstract: Compounds having  alpha  adrenergic activity and useful for the treatment of glaucoma, renal and gastrointestinal disorders and vasoconstictors have the formula  <IMAGE>  where R1 is independently H, or lower alkyl or 1 to 6 carbons; R2 is independently H, or lower alkyl of 1 to 6 carbons or the two R2 symbols jointly represent a carbonyl oxygen; R3 is H, lower alkyl of one to 6 carbons, O, OH and OR7 where R7 is lower alkyl of 1 to 6 carbons, or R3 is COH or COR8 where R8 is lower alkyl of 1 to 6 carbons; R4 and R5 independently is H, Br, Cl, or lower alkyl of 1 to 6 carbons, lower alkenyl or lower alkynyl with the proviso that when the R2 groups symbolize a carbonyl oxygen then R4 and R5 both cannot be hydrogen; R6 is hydrogen, Br, Cl, or lower alkyl of 1 to 6 carbons, lower alkenyl or lower alkynyl, and the R5 and the (2-imidazoline-2-yl)amino substituents are connected mutually exclusively to the 6 and 7 positions of the 1,4-benzoxazine nucleus.
Patent IE-36080-B1 (IE)
Title: Process for preparing a leather substitute having a nap or nubuck grain
IPC: D06N3/10
Filed: 1972-02-14
Abstract: A process for the manufacture of artificial leather which has a napped, suede or nubuck surface finish by contacting a natural, synthetic of semi-synthetic backing member with a polymeric system comprising a mixture of a heat-reactive latex and a carboxylated latex and which contains at least one dyestuff. Each of the latices is cross-linked in sequence while the contacted backing member is dried. The migration of non-polymeric components in the system of latices is suppressed during drying. The backing so treated is mechanically altered on the grain side of the backing member to provide an irregular leather-like surface thereto.
[US3979532A]
Patent IE-48177-B1 (IE)
Title: Pharmaceutical formulations containing cis-platinum(ii)diamminedichloride
IPC: A61K33/243
Filed: 1979-02-01
Abstract: A stable, sterile aqueous solution of cis-platinum (II) diamminedichloride (cisplatin) in a sealed container such as an ampule or vial in unit dosage form suitable for intravenous administration to man has a concentration of cisplatin in the range of from 0.1 to 1.0 mgm/ml. and a pH in the range of from 2.0 to 3.0, preferably about 5.5. The solution can also contain sodium chloride and mannitol.
Patent IE-56248-B1 (IE)
Title: Intraocular lens
IPC: G02C7/04
Filed: 1985-02-06
Abstract: An intraocular lens (1) having an optic (10) of sufficiently small dimension so as to permit its insertion through an incision substantially smaller than 5 mm in length. The lens (1) includes a masking means (21, 22) which is deformable between an exapanded condition in which it masks the edge portion (10a, 10b) of the optic (10) which would otherwise cause a glare effect and a contracted condition in which the masking means (21,22) is located within the confines of said small dimension of the optic (10).
Patent IE-35431-B1 (IE)
Title: New cycloheptene derivatives their preparation and compositions containing same
IPC: C07D209/58
Filed: 1971-05-24
Abstract: 1335129 Dibenzocyclohepta[1,2-c]pyrrole CIBA-GEIGY AG 25 May 1971 [25 May 1970] 16661/71 Heading C2C [Also in Division C5] Novel compounds of the Formula (I) wherein R denotes H, C 1-4 alkyl or allyl, and X denotes H, Cl, CH 3 or CH 3 O, and the addition salts with inorganic or organic acids, may be obtained (1) by reacting a reactive ester of a compound of the Formula II with ammonia or an amine of formula RNH 2 , or (2) by hydrolysing a compound of the Formula IV wherein Z denotes the acyl radical of an organic acid or the cyano group, and when required converting the product into a pharmaceutically acceptable acid addition salt thereof. The preparation of intermediates is described as follows: (9,10-dihydroanthracen-9-yl)methyl ketone is methylated with CH 3 I to give (9- methyl-9,10-dihydroanthracen-9-yl)methyl ketone which is reduced by NaBH 4 to α, 9-dimethyl-9,10- dihydro-9-anthracenemethanol which is rearranged, according to Wagner-Meerwein, in dilute H 2 SO 4 and rearranged to 10,11-dimethyl-5H- dibenzo[a,d]cycloheptene. This latter product can also be obtained by condensing α-phenyl-o-tolylacetonitrile with diethylcarbonate to α-phenyl-otolylcyano-acetic acid ethyl ester, methylating with CH 3 I and boiling with KOH solution to form o-benzyl-hydratropic acid, converting in polyphosphoric acid to 11-methyl-5,11-dihydro- 10H-dibenzo[a,d]cycloheptene-10-one, reacting with CH 3 MgI to form 10,11-dimethyl-10,11- dihydro-5H-dibenzo[a,d]cyclohepten-10-ol and dehydrating in H 2 SO 4 to form 10,11-dimethyl-5H- dibenzo[a,d]cycloheptene. Similar intermediates substituted in the 2-position by chlorine, methyl or methoxy can likewise be obtained. The 10,11- dimethyl-5H-dibenzo[a,d]cycloheptene can be oxidized with SeO 2 to 5H-dibenzo[a,d]cycloheptene-10,11-dicarboxaldehyde which is reduced with NaBH 4 to 5H-dibenzo[a,d]cycloheptene- 10,11-dimethanol which reacts with PBr 3 to form 10,11 - bis - bromomethyl - 5H - dibenzo[a,d]cycloheptene, a compound of Formula II. Corresponding Cl-, CH 3 - and CH 3 O- intermediate compounds are similarly obtained.1,2,3,8-Tetrahydrodibenzo[3,4 : 6,7]cyclohepta[1,2-c]pyrrole - 2-carboxylic acid ethyl ester is obtained by reacting 2 - allyl - 1,2,3,8 - tetrahydrodibenzo[3,4 : 6,7]- cyclohepta[1,2-c] pyrrole with ethyl chloroformate. Pharmaceutical compositions possessing CNS depressant action, adrenolytic and histamineantagonistic action, comprise compounds of Formula (1) above or pharmaceutically acceptable acid addition salts thereof together with a pharmaceutically acceptable carrier or diluent, in forms suitable for administration orally, rectally or parenterally.
[GB1335129A]
Patent IE-34175-B1 (IE)
Title: Serological test devices and a process for their preparation
Inventor: VALLO D
IPC: G01N33/545
Filed: 1970-05-20
Abstract: 1316876 Serological test device LICENCIA TALALMANYOKAT ERTEKESITO VALLALAT 19 May 1970 [24 May 1969] 24098/70 Heading B1X A serological diagnostic test device comprises a test slide which may be of metal, glass, silvered glass or plastics bearing on at least part of one side of a dried coating of a mixture of antigen or antibody linked to a particulate carrier, with an aqueous solution of a natural, semi-synthetic or synthetic film forming watersoluble polymer. The polymer may be polyvinyl alcohol, polyvinyl pyrrolidone, polyvinyl methyl ether, carboxy methyl cellulose, methyl cellulose, gelatin or glue. The aqueous polymer solution may contain merthiolate or sodium thiazide. The slide may be coated with varnish and allowed to dry before application of the diagnostic preparation. Examples relate to slides carrying (1) thyroid antigen bound to polystyrene latex and mixed with polyvinyl alcohol (PVA) or methyl cellulose solution, used for determination of thyroid antibodies; (2) human gamma globulin bound to polystyrene particles mixed with methyl cellulose solution, and used for determining rhematoid factor; (3) human gamma globulin bound to sheep cells and mixed with PVA solution; (4) on one area of the slide, HCG bound to polystyrene particles mixed with PVA solution, on another area anti-HCG serum diluted with PVA solution, for use in pregnancy testing; (5) on one area of the slide HCG bound to sheep cells and mixed with PVA solution, in another area anti-HCG antiserum diluted with PVA solution, also for use in pregnancy testing.
[GB1316876A]
Patent IE-37769-B1 (IE)
Title: Improvements in or relating to brewing
IPC: C12C7/00
Filed: 1973-06-07
Abstract: 1409267 Beer made from two worts J R A POLLOCK 6 June 1973 [27 June 1972 13 Oct 1972 28 March 1973] 30061/72 47404/72 and 14916/73 Heading C6E A first wort having at least 600 mg./l soluble nitrogenous substances, expressed as total nitrogen present, and a minimum α amino acid concentration expressed as nitrogen present of 150 mg./l, and a second wort having at most 200 mg./l soluble nitrogenous substances and a maximum α amino acid concentration of 70 mg./l are fermented separately and then mixed, or the second wort is fermented after mixing it with an incompletely fermented first wort, the product then being fermented to completion. The second wort may contain at least one of sucrose, glucose, fructose, maltose, maltotriose or carbohydrates derived from starch breakdown and may be formed immediately prior to fermentation by dilution of a concentrated solution of one of these materials, which may be pasteurized. Where the first wort is incompletely fermented on mixing, the yeast concentration should be at least 27 gm./l after adding the second wort, and the product of fermentation may be diluted after storing at low temperature and coarse filtering. If both worts are completely fermented before mixing, the second wort should have been fermented with at least 5.7 gm./l yeast, and should have a different, preferably lower, specific gravity than the first wort, which may be concentrated before blending.
[GB1409267A]
Patent IE-52414-B1 (IE)
Title: Interlocking container or cup
IPC: B65D81/34
Filed: 1981-05-04
Abstract: The invention concerns thermoplastics material cups which nest to seal a chamber in the bottom of the lower cup. A thermoplastics material cup (12) for nesting in a like cup has an endless groove (28) on its interior wall spaced from the bottom (16) to interlock with a lug (36) adjacent the bottom (16) of a similar cup. The groove (28) and lug (36) have similarly sloped entry ramps (30, 38) leading to preferably vertical sealing surfaces (32, 40) and the lug (36) is about 10% larger than the groove (28) the dimensions being such that interengagement of the entry ramps (30, 38) causes longtitudinal compression of the lug (36) and consequential radial expansion giving intimate sealing between the sealing surfaces (32, 40) to seal the space (60) in the bottom of the lower cup, so as to keep fresh a comestible located therein.
Patent LU-93011-B1 (LU)
Title: Locator
Inventor: ABU AL-RUBB KHALIL MAHMOUD
IPC: H04W4/02
Filed: 2016-04-01
Granted: 2017-11-08
Abstract: A locator for locating a lost item, the locator comprising: a tag associated with the item, the tag being capable of wireless communication; first and second computing devices, both being capable of wireless communication with one another and with the tag; wherein the first and second computing devices respond to a location of the other of the computing devices and to a location of the tag. Fig. 1 93011
Patent LU-93207-B1 (LU)
Title: Client-Vorrichtung, vernetztes Client- und Benutzervorrichtungs-System sowie Verfahren dafür und Computerprogrammprodukt
Inventor: KHOLODOV ANDRE
IPC: H04L29/08
Filed: 2016-09-13
Granted: 2018-03-16
Abstract: Es wird eine Client-Vorrichtung (30) beschrieben, die ausgebildet ist: mit einer elektrischen Energiequelle (33), einer Client-Steuerung (31), einer bidirektionalen Kommunikationsschnittstelle (32) zur Kommunikation mit einer Benutzervorrichtung (3), zumindest einem Client-Aktor (35), zumindest einem Client-Sensor (36) und verbaut in einem Client-Gehäuse (34), wobei die Client-Vorrichtung (30) mindestens eine Umsetzungsvorrichtung (50) aufweist, um unidirektionale Kommunikationssignale (47) von einem Signal-Aktor (43) von einer nicht-vernetzten Vorrichtung (40) zu detektieren und die Client-Steuerung (31) als Teil der Umsetzungsvorrichtung (50) ausgebildet ist, um die unidirektionale Kommunikationssignale (47) auszuwerten und die bidirektionale Kommunikationsschnittstelle (32) zur bidirektionalen Kommunikation mit der Benutzervorrichtung (3) anzusteuern.
Patent MA-38700-B1 (MA)
Title: Procédé de préparation de morceaux de légumes surgelés
Inventor: LAMAIRE BART
IPC: A23B7/06
Filed: 2014-06-06
Abstract: L'invention concerne un procédé de préparation de morceaux de légumes surgelés, de préférence des morceaux de pommes de terre tels que des frites. Le procédé consiste à placer brièvement les morceaux de légumes au contact d'une substance inerte dont la température est suffisamment basse et pendant une durée suffisamment longue pour amener la couche extérieure des morceaux de légumes à une température inférieure à 0°c pendant qu'une partie intérieure des morceaux de légumes présente une température supérieure à 0°c. Le procédé consiste ensuite à congeler lentement les morceaux de légumes jusqu'à leur surgélation complète au contact de l'air.
Patent MA-44545-B1 (MA)
Title: Procédé de production d'un dérivé de diphénylméthane
Inventor: YOON HEE-KYOON
IPC: C07D409/04
Filed: 2017-06-15
Abstract: La présente invention concerne un procédé amélioré de production d'un dérivé de diphénylméthane qui est efficace comme inhibiteur du cotransporteur du glucose dépendant du sodium (sglt), le procédé étant exécuté à l'aide d'un procédé de synthèse convergent dans lequel chaque groupe majeur est séparément synthétisé et ensuite couplé. Ainsi, comparativement à un procédé de synthèse linéaire présenté dans les documents existants, la voie de synthèse est compacte et le rendement peut être accru, et les facteu
Patent MA-44920-B1 (MA)
Title: Dispositif d'obturation et de verrouillage de dessertes d'eau potable
Inventor: OUDGHOUGH ABDELAZIZ
IPC: E03B7/07
Filed: 2019-02-20
Abstract: La présente invention a pour objet un dispositif d'obturation et de verrouillage anti-fraude. Il est constitué d'une pastille de forme cylindrique et d'une clé à pince intérieure servant à la fixation de la pastille dans la tubulure de la desserte d'eau potable. Ce dispositif anti-fraude est particulièrement destiné à être inséré à l'intérieur de la tubulure de la nourrice ou robinet d'arrêt, permettant la fixation de la pastille après écartement des lèvres situées à l'extrémité de la partie inférieure de la boite directrice, qui s'agrippent à l'extrémité de l'alésage de la pastille, bloquant ainsi le passage d'eau.
Patent CS-221196-B1 (CS)
Inventor: NOVAK IVAN
IPC: B02C2/08
Filed: 1982-03-25
Abstract: Zariadenie je určené na mletie zrnitých
materiálov s tvrdosťou do 5. stupňa tvrdosti.
Podstata zariadenia spočívá v tom, že pozostáva
z hmotného vibračno-rotačného kuželovitého
telesa, tenším koncom letmo upevněného
v excentri pomocou valcovej pružiny
a druhým volným koncom vyčnieva do
pracovnej komory mlecieho zariadenia, přitom
pod napínacím otvorom je na kuželovitom
telese podávacia závltovka.
Zariadenie možno využit v laboratóriach
a skúšobniach výskumných ústavov a výrobných
podnikov zaoberajúcich sa mletím a
drvením zrnitých materiálov.
Patent CS-254514-B1 (CS)
Inventor: BEZDEK JAROSLAV
IPC: E06B9/56
Filed: 1986-03-28
Abstract: Vnější izolační okenní roleta se upevňuje
mezi svislé přiklápěcí lišty a vodorovné přítlačné
těsnicí lišty, které jsou uchyceny na
svislých přiklápěcich lištách. Vrchní těsnicí
lišta je na obou stranách opatřena vodicími
drážkami, jimiž prochází vodicí šrouby, kterými
je tato lišta uchycena na vrchních částech
přiklápěcich lišt. Spodní těsnicí lišta
je uchycena na spodní části přiklápěcich lišt
a je funkčně uzpůsobena na ovládání těsnicích
lišt. Tímto způsobem lze podstatně omezit tepelné
ztráty okenními otvory při jednoduché
manipulaci s okenní roletou i u okenních otvorů
širších rozměrů.
Patent CS-236995-B1 (CS)
Inventor: ERNEST JOSEF
IPC: C02F1/40
Filed: 1983-03-30
Abstract: Způsob destabilizace emulzí ropných
látek v odpadních vodách, spočívající v
tom, že se na emulzí působí kyselinou
sírovou v rozsahu 5 až 6,8 pH a manganistanem
.draselným 1 až 3 kg m"5 při teplotě
50 až 90° C, v průběhu zpětného chladnutí
se odděluje vrchní olejová vrstva.
Patent CS-252332-B1 (CS)
Inventor: THOROVSKY ZDENEK
IPC: C09B45/26
Filed: 1986-04-01
Abstract: Modré 1:2 chromkomplexní azobarvivo
pro barvení vlny a PADu ze slabě kyselé
až neutrální lázně je směsí monosulfonovaného
1:2 chromkomplexu obecného vzorce
I a disulfonovaného 1:2 chromkomplexu
obecného vzorce II, kde vždy znamená
M Na, K, NH4 a X N02 a Y H nebo X H
a Y Cl, v ooměru I:II = 0,05 až 0,95:
0,95 až 0,05.