baber/WOPTO huggingface dataset:
Patent JP-2002179137-A (JP)
Title: Blister packaging body
Inventor: KOJIMA TADASUKE
IPC: B65D75/62
Filed: 2000-12-15
Abstract: PROBLEM TO BE SOLVED: To provide a blister packaging body which can be opened and poured out by one hand a relatively small amount of an item stored such as liquid. SOLUTION: A pair of identical shape storage main bodies (11, 11) are connected together by a stick shape protrusive part 12. A folding line (m) is formed to equally divide the main bodies (11, 11). By folding the protrusive part (12) from the folding line (m) in the depth direction, the protrusive part (12) is separated.
Patent JP-2002182665-A (JP)
Title: Karaoke recording device and karakoke device
Inventor: OZAWA FUTAO
IPC: G10K15/04
Filed: 2000-12-15
Abstract: PROBLEM TO BE SOLVED: To provide a Karaoke recording device having a recording capability excluding noise inputted to a microphone. SOLUTION: The Karaoke recording device is comprised of a 1st recording input interface for obtaining an acoustic signal of Karaoke accompanying music, an acoustic signal of a singing voice generated by a microphone as a generation source, and a non-singing period data; a 2nd recording input interface; a control information interface; a data writing device for writing data in a portable recording medium; a muting means for reducing the acoustic signal level of the singing voice in a period specified by the non-singing period data; a means for making the mixed signal of the acoustic signal of the singing voice adjusted to this level and the acoustic signal of the Karaoke accompanying music obtained by the 1st recording input interface into a recorded file in music units in a prescribed data form;  and a recording control device for writing the recorded file in the portable recording medium by the data writing device.
Patent JP-2002184158-A (JP)
Title: Media reproducing device and media reproducing method
Inventor: SHIRAKAWA SHOJI
IPC: G11B27/10
Filed: 2000-12-15
Abstract: PROBLEM TO BE SOLVED: To selectively reproduce music data liked by a user. SOLUTION: These device and method are realized by providing a reproducing part 7 to reproduce plural pieces of the music data recorded in media, an input part 2 to input a skip command to interrupt reproduction of the music data by the reproducing part 7 and to skip the reproduction to the one of the music data scheduled to be reproduced next, a control part 10 to perform control to interrupt the reproduction of the music data currently under reproduction according to the skip command inputted from an input part 2 and to reproduce the music data scheduled to be reproduced next and a storage medium 6 to store music data number information to specify the musical data the reproduction of which by the reproducing part 7 is interrupted according to the input of the skip command from the input part 2 by paring it with a TOC(Table Of Contents) information of the media.
Patent JP-2002177888-A (JP)
Title: Foreign matter separation apparatus for garbage-like waste
Inventor: YOSHIDA TERUHIKO
IPC: B09B5/00
Filed: 2000-12-18
Abstract: PROBLEM TO BE SOLVED: To provide a foreign matter separation apparatus which can continuously fractionate a large amount of a garbage-like waste. SOLUTION: A rotary shaft 5 is installed along the central axis of an arcing wall 3a of a tubular body 2 having a wall 3 of which a part of the cross section is in the form of an arc; a plurality of platy blades 6 each having a tip edge 7 slidable along the arcing wall 3a and extending along the rotary shaft 5 are fixed to the rotary shaft 5; a plurality of fine through-holes 10 are formed on the arcing wall 3a of the tubular body 2; an airflow channel 12 extending in the longitudinal direction of the tubular body 2 is formed between the non-arcing wall 3b of the tubular body 2 and the tip edge 7 of the platy blade 6; an airflow guide means 14 which guides an airflow G in the airflow channel 12 in the longitudinal direction of the tubular body 2 is installed;  and at the airflow upstream site of the tubular body wall 3, a waste A charge port 16 is formed in the direction crossing the central axis. A garbage- like waste A charged through the charge port 16 into the tubular body is crushed by the rotation of the platy blades 6; then, foreign matters B are separated from the waste A and conveyed out of the tubular body 2 by the airflow G; and the waste C freed from the foreign matters is discharged through fine through-holes 10.
Patent JP-2002188403-A (JP)
Title: Hydraulic equipment
Inventor: YOSHIDA MINORU
IPC: F04D29/34
Filed: 2000-12-19
Abstract: PROBLEM TO BE SOLVED: To enhance durability of a vane and suppress occurrence of vibration and noise in the vane. SOLUTION: The equipment comprises a vane support part that is rotationally supported, and a plurality of vanes 21 formed, by being projected radially outward at plural positions in the circumferential direction of the vane support part. The vane 21 is comprised of a first vane element, extending radially outward from a first fixing position p1 on the vane support part, a second vane element extending radially outward from a second fixing position p2 on the vane support part, and of a third vane element coupling the first and the second vane elements. The first and the second vane elements are formed, by being projected radially outward from the vane support part, while being connected by the third vane element, which enables suppression of damage to the vane 21 sustained when receiving force from outside, etc., thus enhancing the durability of the vane 21.
Patent JP-2002192827-A (JP)
Title: Printing method
Inventor: OGURA KAZUHIKO
IPC: B41M5/00
Filed: 2000-12-22
Abstract: PROBLEM TO BE SOLVED: To provide a printing method, with which a predetermined printing and a reversal printing or a printing, in which the surface of the predetermined printing is reversed to its back, can be performed easily at low cost. SOLUTION: In the first process (a), a first printing A is applied by an ink jet printer 3 with a water-based colored ink 4 on a receiving layer 12. In the second process (b), before the hardening of the ink 4, the printing surface of a first printing object 1 is faced to a second printing object 2 made of a plain paper. In the third process (c), by separating both the printing objects 1 and 2, a printing result applied by the predetermined printing A with the ink 4 absorbed in an ink receiving layer 12 is obtained on the first printing object 1 while a printing result applied by a reversal printing B with the ink 4 transferred from the first printing object 1 is obtained on the second printing object 2.
Patent JP-2002188731-A (JP)
Title: Opening/closing valve for high pressure fluid
Inventor: OZAWA KENJI
IPC: F16K1/34
Filed: 2000-12-25
Abstract: PROBLEM TO BE SOLVED: To provide an opening/closing valve for high pressure fluid reducing the abrasion of a seal mechanism of a valve element. SOLUTION: The opening/closing valve is provided with a valve body 2 provided with a fluid inlet passage 6, a fluid outlet passage 7 and a cavity 5 communicated with the fluid inlet passage 6 and the fluid outlet passage 7; a valve element 3 disposed in the cavity 5 of the valve body 2; a valve element operation part 18 for operating the valve element 3; and a seal mechanism of the valve operation part 18. The cavity 5 has a first seat part 10 for shielding the fluid inlet passage 6 and a second seat part 10 for shielding the seal mechanism (15). The valve element has a first butting part 3a capable of abutting to a first seat part 8 and a second butting part 3b capable of abutting to the second seat part 10.  At the time of closing a valve, the valve element 3 is seated on the first seat part 8 by the first butting part 3a by urging the valve element 3 by the valve operation part 18. At the time of opening the valve, the valve element 3 is seated on the second seat part 10 by the second butting part 3b by leaving the valve element 3 by the valve operation part 18. Thereby, the seal mechanism (15) of the valve operation part 10 is isolated from the high pressure fluid.
Patent JP-2002198206-A (JP)
Title: Thermistor
Inventor: HAGA GAKUO
IPC: H01C7/02
Filed: 2000-12-26
Abstract: PROBLEM TO BE SOLVED: To provide a thermistor which is reduced in resistance and improved in withstand voltage, keeping breaking grooves enough in depth and itself enough in element strength and to restrain the thermistor element from tilting or going out of position, when lead wires are fixed in a process in which the thermistor is modified into a lead type. SOLUTION: A thermistor mother board is divided along breaking grooves into thermistor elements, a recess is provided to at least the one main surface of the thermistor element, an electrode is formed on the opposed surface that contains the recess, and the one end of a lead wire is soldered to the electrode, extending along the inner wall of the recess.
Patent JP-2002195298-A (JP)
Title: Electromagnetic clutch
Inventor: NAKAGAWA JUNICHI
IPC: F16D27/112
Filed: 2000-12-26
Abstract: PROBLEM TO BE SOLVED: To adequately prevent the electromagnetic clutch (especially a friction surface of armatures) from being stained with oil. SOLUTION: A tapered part 140d becoming gradually wider increasing the diameter of an internal circumferential wall surface 140c towards the direction opposite to the friction surface 141c is formed on the circumferential groove 150 and the internal circumferential wall surface 140c of the armature 140 surrounding the armature 140. Hence, even if oil is dropped on the electromagnetic clutch 10 on the inspection of an engine or in supplementing of oil, the oil dropped flows downwards along the circumferential groove 150 (wall surface 151) and drops from the electromagnetic clutch 100 without flowing towards the friction surface side 141c.  Oil which is stuck on the head of a bolt 111 and arrives at the internal side wall surface 140c flows to the opposite side of the friction surface 141c and is dropped out of the electromagnetic clutch 100 without flowing to the side of the friction surface 141c disturbed by the tapered part 140d.
Patent JP-2002197287-A (JP)
Title: Life bank system
Inventor: KAJINUMA ATSUSHI
IPC: G06Q50/00
Filed: 2000-12-27
Abstract: PROBLEM TO BE SOLVED: To sign in and save data of personal information such as personal history, asset management and a will on a registration site on the Internet, to add or change those data as needed, and to register a reservation to meet member's living wills. SOLUTION: This invention enables to create a web site to keep various information regarding the members on the Internet, and to allow the members to add latest information to the site, to browse the whole or part of the information, to provide the information to the designated persons, to disclose them and to specify the timing of disclosure. Thus, the members are able to store the information permanently, to complete the personal histories, to provide or publish the data to the third parties or the general public, and to realize the members' wills or wishes after ones' death.
Patent JP-2002195135-A (JP)
Title: Operation simulation device and operation simulation method for fuel injection system
Inventor: OKAMOTO ATSUYA
IPC: G01M15/02
Filed: 2000-12-27
Abstract: PROBLEM TO BE SOLVED: To provide an operation simulation device, an operation simulation method, and a record medium recording an operation simulation program for a fuel injection system of an accurate common rail system. SOLUTION: An electromagnetic field analysis part 21 calculates electromagnetic characteristics including effect of eddy current generated at an electromagnetic actuator provided in a solenoid valve part in a prescribed calculation timing. The calculated electromagnetic field characteristics are transferred to a hydraulic valve system analysis part 22. The hydraulic valve system analysis part 22 calculates hydraulic valve system characteristics such as behaviors of an injector valve needle, behaviors of a valve member of the solenoid valve part, and injection rate of fuel injected from an injection hole based on injector design data and the electromagnetic field characteristics. The calculated hydraulic valve system characteristics are transferred to the electromagnetic field analysis part 21 and are used for electromagnetic field analysis in a next calculation timing.  The electromagnetic field analysis and the hydraulic valve system analysis are concurrently executed with using mutual calculation results.
Patent JP-2001247913-A (JP)
Title: Heating furnace for steel material and method for heating steel material for hot rolling
Inventor: TERAURA KAZUHIRO
IPC: C21D9/00
Filed: 2000-12-27
Abstract: PROBLEM TO BE SOLVED: To provide a heating furnace and method, with which scale amount formed on a steel material surface is restrained and the yield of the steel material is improved. SOLUTION: One of partition wall near an ejecting hole door and further, one or more of the partition walls at a charging hole side from the ejecting hole door, are arranged, and a zone parted with the partition walls, is repeatedly subjected to combustion and suction with heat-storage type burners and heated with <1% oxygen concentration in the zone.
Patent JP-2002155252-A (JP)
Title: Aqueous emulsion for adhesive and its composition
Inventor: OTSUKA MASAHIKO
IPC: C09J125/14
Filed: 2000-12-28
Abstract: PROBLEM TO BE SOLVED: To provide an aqueous emulsion capable of giving an adhesive which comprises a water-soluble resin, the aqueous emulsion and an isocyanate compound, and has good pot life, adhesivity under normal conditions, water-resistant adhesivity and heat-resistant adhesivity, and to provide a composition of the aqueous emulsion. SOLUTION: This aqueous emulsion obtained by emulsion-polymerizing a specific monomer composition, having a specific average particle diameter, and giving the adhesive having good pot life, adhesivity under normal conditions, water-resistant adhesivity, and heat-resistant adhesivity.
Patent JP-2002191748-A (JP)
Title: Compound type variable display device and slot machine game machine
Inventor: NAGAHAMA ETSUYA
IPC: A63F5/04
Filed: 2000-12-26
Abstract: PROBLEM TO BE SOLVED: To realize a variety of display related to the progress of game by systematically combining multiple varying patterns of expression simultaneously. SOLUTION: A plurality of rotary reels 31, 32 and 33 are arranged in parallel sideways and a plurality of figures are described at a specified interval on the surface of the outer circumference of the rotary reels 31, 32 and 33. A part of the surface of the outer circumference of the respective rotary reels 31, 32 and 33 face display windows 22, 23 and 24 opened at a front panel 20. The rotary reels are rotated with a driver led by the operation of a start lever 26 and thereafter, the rotary reels are stopped by the operation of a stop button 29. Winning or losing is determined depending on the stop position of the figures.  A compound presentation device is so arranged as to comprise a casing 60, a plurality of variable display rotary reels 6, 7 and 8 rotatably installed inside the casing 60 and an electronically luminous display device 40 securely installed on the casing 60 inside the plurality of variable display rotary reels. The compound presentation device is arranged facing display windows 2, 3 and 4 for presentation opened at the front panel 20 to show various display figures and images for presentation associated with the winning and losing.
Patent JP-2001511359-A (JP)
IPC: C12N15/09
Filed: 1998-07-22
Abstract: Tags and linkers specifically designed for a wide variety of nucleic acid reactions are disclosed, which are suitable for a wide variety of nucleic acid reactions wherein separation of nucleic acid molecules based upon size is required.
Patent JP-2001518517-A (JP)
IPC: A61K48/00
Filed: 1998-10-01
Abstract: Described is the modulation of the neovascularization and/or growth of collateral arteries and/or other arteries from preexisting arteriolar connections. Methods are provided for enhancing neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections comprising contacting organs, tissue or cells with a colony stimulating factor (CSF) or a nucleic acid molecule encoding said CSF. Furthermore, the use of a CSF or a nucleic acid molecule encoding said CSF for the preparation of pharmaceutical compositions for enhancing neovascularization and/or collateral growth of collateral arteries and/or other arteries from preexisting arteriolar connections is described. Also provided are methods for the treatment of tumors comprising contacting an organ, tissue or cells with an agent which suppresses neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections through the inhibition of the biological activity of CSFs. Described is further the use of an agent which suppresses neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections through inhibition of the biological activity of CSFs for the preparation of pharmaceutical compositions for the treatment of tumors.
Patent JP-2001525167-A (JP)
Title: 熱安定グルコアミラーゼ
IPC: C12P19/20
Filed: 1998-11-26
Abstract: (57)【要約】
本発明は澱粉転化法に適している、タラロミセス・エメルソニイ由来の単離された熱安定グルコアミラーゼに関する。
Patent JP-2001526217-A (JP)
Title: 血管性頭痛に対する局所麻酔薬の新規な使用
IPC: A61K31/135
Filed: 1998-12-14
Abstract: (57)【要約】
本発明は、血管性頭痛病態、特に片頭痛を治療する医薬を製造するための式（Ｉ）
【化１】
 （式中、Ｒ 1 はＣ 3-5 アルキルを示し、Ｒ 2 およびＲ 3 は、独立してＣ 1-3 アルキルを示す）の化合物またはその医薬的に許容し得る塩の新規な使用を開示する。
Patent JP-2001527308-A (JP)
Title: 伸縮自在アンテナ付無線電話機用アンテナシールド
IPC: H01Q9/36
Filed: 1998-12-18
Abstract: (57)【要約】
伸縮自在アンテナ付無線電話機用シールドは電子的接地と操作可能に関連され、好ましくはアンテナが引っ込められた位置にある時に操作可能な整合回路内にインダクタもしくはキャパシタを形成するように構成された導電性管状アンテナ案内を含んでいる。関連する方法は無線電話機内部に配置されたアンテナから生じるＲＦ放射を縦方向出口経路に沿って無線電話機から外へ指向することを含んでいる。
Patent JP-2002500186-A (JP)
Title: ピロニン抗菌剤、方法および新規の中間体
IPC: C07C49/203
Filed: 1999-01-04
Abstract: (57)【要約】
本発明は、ミキソピロニンおよびコラロピロニン、抗菌治療に有用な化合物、を調製するための収斂方法を提供する。本発明はまた、ピロニン抗生物質の調製に有用な新規の組成物を提供する。
Patent JP-2002500072-A (JP)
Title: 皮下移植装置を消毒する方法および機器
IPC: A61M37/00
Filed: 1999-01-05
Abstract: (57)【要約】
移植ポート（１０）および他の装置は、この装置内の領域またはこの装置を取り囲む組織嚢に抗菌剤を注入することにより、消毒される。第一実施態様では、この抗菌剤は、この組織嚢を浸出する前、およびこの装置に通じる組織路を通って外向きにフラッシュする前に、この装置の内部領域をフラッシュするために、この装置の開口部（１２）を通って注入される。他の実施態様では、この抗菌剤は、この装置の外部にある標的部位に直接注入される。移植装置は、この抗菌剤を注入するのに使用される針の鋭い末端を受容するための特別な（通常、硬くした）標的領域を包含し得る。キットは、本発明の方法に従って消毒するために、装置、注射器、アクセス装置および使用説明書を包含する。
Patent JP-2002502964-A (JP)
Title: 容量型ベースの圧力センサ設計
IPC: G01L9/00
Filed: 1999-01-11
Abstract: (57)【要約】
開示した圧力変換器アセンブリは、第１の本体と、第２の本体と、ダイヤフラムと、電極を含んでいる。第１の本体はケースと、１以上のスポークと、ハブとを含んでいる。ケースは内部表面を有する。各前記スポークは第１の端部から第２の端部まで延在する。各スポークの第１の端部は内部表面と接触し、各スポークの第２の端部はハブと接触する。ダイヤフラムは第１の本体と第２の本体との間に取付けられている。第１の本体とダイヤフラムは第１の室を形成する。第２の本体とダイヤフラムは第２の室を形成する。ダイヤフラムの一部は第２の室の圧力よりも高い前記第１の室の圧力に応答して第１の方向に曲がる。ダイヤフラムの一部は第１の室の圧力よりも高い第２の室の圧力に応答して第１の方向と反対の第２の方向に曲がる。電極は第１の室に配置されハブに固定される。電極とダイヤフラムの間のキャパシタンスは第１および第２の室の圧力の差を表している。
Patent JP-2002504459-A (JP)
Title: エアドライアタンクモジュール部品
IPC: F15B21/048
Filed: 1999-02-25
Abstract: (57)【要約】
エアコンプレッサ（２０）及び二次エアタンク（１２）から圧縮空気を入力するように連結されるエアドライア（１４）と、エアドライア（１４）を通過する圧縮空気システムを保持させるパージ容積部（３４）とを含み、重量車上のエアコンプレッサ（２０）から圧縮空気を与えるエアドライアタンク装置。エアドライア（１４）及び二次エアタンク（１２）はハウジング（１６）に対し固設されてエアドライアタンクモジュール（１０）が形成される。エアドライア（１４）からの圧縮空気を保持する一次タンク（１８）はエアドライアタンクモジュール（１０）から離間して配置される。等圧化機構（５７）は一次タンク（１８）と二次エアタンク（１２）との間に配設され２タンク（１２、１８）の圧力を等しく維持する。ハウジング（１６）内に配設された構成部品はエアドライア（１４）と一次及び二次タンク（１８、１２）との間を流れるエアの流れを制御し、また一次及び二次タンク（１８、１２）により付勢される気圧ブレーキシステム回路をモニターする。
Patent JP-2002506079-A (JP)
IPC: A61K47/48
Filed: 1999-03-10
Abstract: The present invention provides a method of identifying a membrane dipeptidase (MDP)-binding homing molecule that selectively homes to lung endothelium. The method includes the steps of contacting MDP with one or more molecules; and determining specific binding of a molecule to the MDP, where the presence of specific binding identifies the molecule as a MDP-binding homing molecule that selectively homes to lung endothelium. Such MDP-binding homing molecules can be linked to a moiety and, when administered to a subject as a conjugate, can selectively direct the moiety to lung endothelium in the subject.
Patent JP-2002507827-A (JP)
Title: 電子回路または構成部品を収容するためのシールドされたハウジング
IPC: H05K9/00
Filed: 1999-03-15
Abstract: (57)【要約】
本発明は、電磁気干渉界または照射干渉界に敏感な電子回路または構成部品用のシールドされたハウジング（１、２）に関する。ハウジングは、接続ケーブル、プラグ（４）などの形状の電気的接続に適合していて、閉成された金属層（８）（導電性の材料で形成された）の形状のシールドと、特に接続部がハウジングに入るか貫通する領域（３）の干渉界に対して作用するフィルター装置を同様に有する。本発明は、少なくとも入り口と貫通部の前記領域（３）に位置され、接続部材とシールドの一体的構成部品として具体化され、ハウジング壁でもあるコンデンサ（５、６、７）を持ったフィルター装置を提供する。
Patent JP-2002507872-A (JP)
Title: コネクション処理の際に安全性に関係している機能を制御する方法、移動局および無線通信システム
IPC: H04Q7/38
Filed: 1999-02-10
Abstract: (57)【要約】
加入者認証および情報の秘密保持を有するコネクション処理の際に安全性に関係している機能を制御するための公知の方法ないし無線通信システムから出発して、通信ネットワークが無線インタフェース上で暗号化された情報を有するコネクションを希望するかまたは暗号化されていない情報を有するコネクションを希望するかについての識別符号（ｃｉｍｏｄｅ）を有する暗号化要求が移動局（ＭＳ）によって受信されかつ評価される。その際移動局（ＭＳ）は、受信された識別符号（ｃｉｍｏｄｅ）が暗号化されていない情報を有するコネクションを許容するとき、コネクション（例えばｖ１）が中断される作動モードに加入者制御されて切換可能である。暗号化されていない情報の盗聴が無線加入者によって所望されなければ、加入者制御されて情報の盗聴されない伝送を必要に応じて保証することができる。
Patent JP-2002507662-A (JP)
IPC: C21D1/53
Filed: 1998-04-30
Abstract: A method for rapid heat treatment, quenching and aging of an article includes placing the article in a fluidized bed and conveying the article through the bed. Heat treatment, quenching and aging of the part can be done in less than two hours using this method. The method also includes removing fluidizing media from the article as the article is removed from the fluidized bed. An elevator is used to remove the article from the fluidized bed. The elevator may include a conveyor for moving the article into another fluidized bed. The article can then be placed into the second fluidized bed and conveyed through that bed. Each fluidized bed is controlled so that a specific heat treatment can be applied to the article by the fluidized bed. The fluidized bed can be used as a portion of an automated production line. The retort of the fluidized bed includes a system for recycling the air passed through the fluidizing media in the furnace. The recycling system includes a fan positioned above the fluidizing media in the retort, a filter for removing any fluidizing media within the recycled air, and piping for reintroducing the recycled air to the retort. The heaters are placed within the retort and include heat exchangers for heating the incoming combustion air. The heaters are rigidly attached at one end and fit within sleeves attached to another portion of the retort. The heater tubes can be replaced with refrigeration tubes or units so that articles may be quenched.
Patent JP-2002510867-A (JP)
Title: 広帯域で平坦な利得ダイナミックレンジを有する光アンプ
IPC: H01S3/06
Filed: 1999-02-09
Abstract: (57)【要約】
光アンプは、光ファイバ・セグメント（２０）内を伝播する光信号に光利得を提供するエルビウム等の不純物イオンがドープされた光ファイバ・セグメントからなる。第１励起波長の第１のソース（５０）は、第１の基底状態から第２の準安定状態にイオンを励起する。準安定状態は、誘導放出によって基底状態に崩壊して光利得を提供する。第２励起波長の第２のソース（６０）は、基底状態から第３の補助状態にイオンを励起する。補助状態は、準安定状態に崩壊する。したがって、一方又は両方の励起波長の励起パワーを制御することによって、準安定状態のイオンの一部を制御することが可能である。これによって、利得スペクトルの形状に実質的に影響を及ぼすことなく利得スペクトルの全体的なスケールファクタの制御が可能になる。
Patent JP-2002511409-A (JP)
IPC: A61K31/198
Filed: 1999-04-14
Abstract: A pharmaceutical composition comprising (i) at least one agonist of the glycine site of an NMDA receptor and (ii) a second therapeutic agent which is a antipsychotic, antidepressant, psychostimulants or Alzheimer's disease therapeutic. The agonist is D-alanine, a salt of D-alanine, an ester of D-alanine, alkylated D-alanine, a precursor of D-alanine, D-serine, a salt of D-serine, an ester of D-serine, alkylated D-serine, a precursor of D-serine, D-cycloserine, a salt of D-cycloserine, an ester of D-cycloserine, a precursor of D-cycloserine, or alkylated D-cycloserine. The pharmaceutical composition is substantially free of D-cycloserine when the agonist is D-alanine, a salt of D-alanine, an ester of D-alanine, an alkylated D-alanine, or a precursor of D-alanine. Where the agonist is D-cycloserine, a salt of D-cycloserine, an ester of D-cycloserine, a precursor of D-cycloserine, or alkylated D-cycloserine, the pharmaceutical composition comprises an amount of the agonist equivalent to 105-500 mg of D-cycloserine.