baber/WOPTO huggingface dataset:
Patent PT-1255749-E (PT)
Title: Tyrosine derivatives with anti-leukotriene activity
Inventor: MAKOVEC FRANCESCO
IPC: A61P11/06
Filed: 2001-02-07
Abstract: Compounds which can be represented by general formula (I) indicated below and in which:R1 and R2 are selected, independently, from hydrogen, an alkyl group having from 1 to 4 carbon atoms, a halogen group such as a fluoro, chloro or bromo group, the methoxy group, the cyano group, or the trifluoromethyl group, andR3 is selected, independently, from a phenyl or a 2 (or 3 or 4)-pyridyl group, unsubstituted or mono- or di-substituted with an alkyl or alkoxy group having from 1 to 4 carbon atoms, with a halogen group such as a fluoro or chloro group, with the trifluoromethyl group, with the cyano group, with the nitro group, with the amino group, or with the phenyl group, a 1 (or 2)-naphthyl group, a 2 (or 3)-indolyl group as such or N-alkylated with an alkyl group having from 1 to 3 carbon atoms, a 2 (or 3, 4, 5, 6, 7 or 8)-quinolinyl or a 1 (or 3, 4, 5, 6, 7 or 8)-isoquinolinyl group, unsubstituted or mono- or di-substituted with a group selected, independently, from the methyl, ethyl, propyl, isopropyl, methoxy, fluoro, chloro, trifluoromethyl, cyano, amino, or nitro groups, a 2 (or 5 or 6)-quinoxalyl group, a (or 4, 5, 6, 7 or 8) cinnolyl group, or a 2 (or 4, 5, 6 or 7)-benzimidazolyl group, and in which the configuration of the chiral centre marked with an asterisk (*) in the general formula (I) may be, independently, L, D or DL (racemic).
Patent PT-1317273-E (PT)
Inventor: DEGLON NICOLE
IPC: A61K38/20
Filed: 2001-09-10
Abstract: The invention relates to the use of an IL-6R/IL-6 chimera, a mutein, isoform, fused protein, functional derivative, active fraction or circularly permutated derivative or a salt thereof, for the manufacture of a medicament for the treatment and/or prevention of Huntington's disease.
Patent PT-1349449-E (PT)
Inventor: LINDVALL TOMMY
IPC: A01K1/035
Filed: 2001-11-26
Abstract: A livestock pen with ends and long sides for permanently restricting the freedom of movement of animals kept therein. The livestock pen contains a moving, endless belt that supports all the weight of the animals. The belt is arranged to move from an inlet end towards an outlet end. An outlet end panel forms a gap between the belt and the outlet end panel's lowermost transverse member. At the belt's outlet end, a sensing means, when actuated, stops any ongoing belt movement. An additional aspect relates to a method for stopping the movement of an endless belt in a livestock pen, whereby a sensing means registers when a part of an animal is in a restricted area of the livestock pen. A signal from the sensing means then stops the belt's drive mechanism.
Patent PT-1560811-E (PT)
Title: Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-iv (dpp-iv)
Inventor: STEWART KENT D
IPC: C07D417/12
Filed: 2003-09-15
Abstract: The present invention relates to compounds of formula I which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, Syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases. Or pharmaceutically acceptable salts or prodrugs thereof, wherein X,R,R<1>,R<2> and R<3> have the definitions given in the description.
Patent PT-1532606-E (PT)
Inventor: CHRISTIAN SONDERGAARD
IPC: G09F19/18
Filed: 2003-08-22
Abstract: The invention relates to an advertisement print being printed on a print carrier. The print illustrates a transformation of a three-dimensional element, where the print is optimized for a viewer having two viewpoints, a first viewpoint and a second viewpoint being placed on each side of a central fictive viewpoint. The print comprises a right side being a perspective projection of said three-dimensional element to said print carrier, where the projection is optimized to the firt viewpoint. Further, the print comprises a left side being a perspective projection of the three-dimensional element to the print carrier, where the projection is optimized to the second viewpoint.
Patent PT-1457279-E (PT)
Inventor: RODE DIRK DR
IPC: B22D11/06
Filed: 2004-02-17
Abstract: A process for production of hollow cylindrical casting rolls (1,1a) in Cu or Cu alloy by first casting hollow cylinder (2, 5), the wall thickness of which is increased by coatings (4,7) on its inner surface (3) and/or on its outer surface (6). An independent claim is included for a casting roll (1,1a,11) cast from a hollow cylinder coated on its inner and/or outer surface.
Patent PT-1437131-E (PT)
Title: Use of ramipril for the prevention of diabetes in a patient with no preexisting congestive heart failure
Inventor: BENDER NORBERT
IPC: A61K31/497
Filed: 2000-08-25
Abstract: Novel use of an inhibitor of the renin-angiotensin system or derivative (I) in the manufacture of a medicament for the prevention of stroke in patients exhibiting normal or low blood pressure, diabetes and/ or congestive heart failure (CHF) with no pre-existing CHF. Independent claims are also included for: a method of preventing of stroke in patients exhibiting normal or low blood pressure, diabetes and/ or congestive heart failure (CHF) with no pre-existing CHF; and a formulation for use in the prevention of stroke in patients exhibiting normal or low blood pressure, diabetes and/ or congestive heart failure (CHF) with no pre-existing CHF. ACTIVITY : Cerebroprotective; Cardiant; Antidiabetic. Treating 9,541 patients who are at risk for cardiovascular events due to a history of previous ischemic heart disease, stroke, peripheral arterial disease or individuals with diabetes with ramipril for 6 years resulted in a 32% reduction in the number of patients who developed a stroke, 21% who developed congestive heart failure, and 36% reduction who developed diabetes. MECHANISM OF ACTION : Angiotensin converting enzyme (ACE) inhibitor; an angiotensin II antagonist.
Patent PT-1629091-E (PT)
Title: Composition containing the polyprotein ns3/ns4 and the polypeptide ns5b of hcv, expression vectors comprising corresponding nucleic sequences and the therapeutic application thereof
Inventor: INCHAUSPE GENEVIEVE
IPC: A61K48/00
Filed: 2004-06-04
Abstract: Composition (A) comprising a NS (non-structural) 3/NS4 polyprotein (I) and a NS5b polypeptide (II), both from hepatitis C virus (HCV). Independent claims are also included for: (1) expression vector (EV) that contains sequences encoding (I) and (II), plus necessary expression elements; (2) microorganisms and host cells transfected by EV; (3) antibodies (Ab) directed against (A) or EV; and (4) pharmaceutical composition or kit, particularly a vaccine, that contains (A), EV or Ab. ACTIVITY : Virucide; Hepatotropic. Mice were vaccinated with an adenovirus (Ad) that expressed HCV proteins, then inoculated with a recombinant vaccinia virus that expressed non-structural HCV proteins. Neutralization of vaccinia was determined 4 days later by a plaque-reduction assay on ovarian extracts. For 8 animals vaccinated with a control Ad, the total score was 77, but for 8 animals injected with two AdV that expressed NS3/NS4 and NS5b had a score of 52, i.e. the neutralization of virus was significantly more effective. Combinations of viruses that expressed NS3/NS4 and NS5b and either of NS5a or CE1E2 were no more effective than the control virus. MECHANISM OF ACTION : Vaccine; Passive immunization.
Patent PT-1806136-E (PT)
Title: Medicinal composition for prevention of transition to operative treatment for prostatic hypertrophy
Inventor: OKUBO YOSHIO
IPC: A61K31/4045
Filed: 2005-10-04
Abstract: The present invention provides an agent useful for the prevention of transition to surgical therapy for benign prostatic hyperplasia and the like. The present invention relates to a pharmaceutical composition for the prevention of transition to surgical therapy for benign prostatic hyperplasia, which comprises an indoline derivative represented by the following general formula (I) or a pharmaceutically acceptable salt thereof (in the formula, R represents an optionally substituted aliphatic acyl group, a hydroxyalkyl group, an aliphatic acyloxyalkyl group, a substituted lower alkyl group, an optionally substituted aromatic acyl group, a furoyl group, a pyridylcarbonyl group or the like; R 1  represents a cyano group or a carbamoyl group; and R 2  represents an optionally substituted lower alkyl group).
Patent PT-1776975-E (PT)
Title: Medication injector apparatus with drive assembly that facilitates reset
Inventor: ATTERBURY WILLIAM GODWIN
IPC: A61M5/31
Filed: 2002-05-08
Abstract: A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. When the cartridge assembly is not mounted to the pen base, the floating nut and drive clutch are biased distally to disengage the drive clutch from torque transmitting engagement with the rotatable drive member and to thereby allow the drive screw to be reset proximally through the nut to a position more retracted within the pen base. The injection pen includes a doseable quantity identifier that uses a rotational matrix (500) and a sensor (502) for electrically sensing the arrangement of the dose setting mechanism of the pen, which identifier may be part of a therapeutic dose indicating system that utilizes a cartridge recognizer to recognize a concentration of medication so as to allow an automatic determination of a therapeutic dose. The injection pen further may include an assembly for selectively rotating a drive sleeve of the pen, which assembly has a dial that rotates out during dose setting and which translates in without rotation during dose injecting.
Patent PT-1924807-E (PT)
Title: Energy transfer system and associated methods
Inventor: JAGUSZTYN TADEUSZ FRANK
IPC: F24V50/00
Filed: 2006-09-15
Abstract: An energy transfer system includes an energy transfer device, a water inlet pipe and a water outlet pipe. The water inlet pipe may be connected to a water inlet of the transfer device to extract water from a water source. The water outlet pipe may be connected to a water outlet on the energy transfer device to discharge water to the water source. The water inlet pipe may extract water from a predetermined extraction depth, and the water outlet pipe may discharge water into the water source at a predetermined discharge depth.
Patent PT-2056291-E (PT)
Title: Signal processing method, processing apparatus and voice decoder
Inventor: ZHAN WUZHOU
IPC: G10L19/005
Filed: 2008-11-04
Abstract: The present invention discloses a signal processing method adapted to process a synthesized signal in packet loss concealment. The method includes the following steps: receiving a good frame following a lost frame, obtaining an energy ratio of energy of a signal in the signal of the good frame signal to energy of a synthesized signal corresponding to the same time of the good frame; and adjusting the synthesized signal in accordance with the energy ratio. The present invention also discloses a signal processing apparatus and a voice decoder. Through using the method provided by the present invention, the synthesized signal is adjusted in accordance with the energy ratio of the energy of the first good frame following the lost frame to the energy of the synthesized signal to ensure that there be not a waveform sudden change or an energy sudden change at the place where the lost frame and the first good frame following the lost frame are jointed in the synthesized signal, to realize the waveform's smooth transition and to avoid music noises.
Patent PT-2145026-E (PT)
Title: Biomass treatment process
Inventor: HEATHCOTE JOHN GERVASE MARK
IPC: B01F3/12
Filed: 2008-05-02
Abstract: A process for the treatment of biomass is provided. The process comprises forming a biomass slurry by mixing biomass with a working fluid, and inducing the biomass slurry to flow through an inlet into a passage. A high velocity transport fluid is injected into the slurry through a nozzle communicating with the passage. The injection of the high velocity transport fluid applies a shear force to the slurry such that the working fluid is atomised and forms a vapour and droplet flow regime, an at least partial vacuum is formed within the passage downstream of the nozzle, and a condensation shock wave is generated within the passage downstream of the nozzle and vacuum by condensation of the transport fluid. An apparatus for treating biomass using the aforementioned process is also provided.
Patent PT-2231575-E (PT)
Title: Process for the preparation of pharmaceutical intermediates
Inventor: TIBOR MEZEI DR
IPC: C07C45/68
Filed: 2008-11-27
Abstract: The invention relates to a process for the preparation of cyclopropyl benzyl ketone compounds of formula (II) wherein R1 represents fluorine or chlorine atom or C1-4 alkoxy group, by the reaction of a Grignard reagent, obtained from the reaction of compound of formula (V), wherein X represents chlorine or fluorine atom, with the compound of formula (IV), wherein R2 represents C1-4 alkyl group, having a straight or branched chain. The process can be applied preferably on industrial scale. Compound of formula (II), wherein R represents a fluorine atom in position 2 is an intermediate of the preparation process of prasugrel, which is a platelet inhibitor used in the therapy.
Patent PT-645081-E (PT)
Inventor: KARG JORN E
IPC: A61L9/12
Filed: 1994-09-28
Abstract: Device according to the following figure which can be used to combat insects, characterised in that it comprises:   * a container (1) made from transparent plastic in the shape of a dish, the open face of which has a flat edge, * a sheet (3) of plastic which is impermeable to liquids and permeable to the vapours of essential oils at room temperature, this sheet being fastened to the flat edge of the transparent container and adhering to this transparent container so that it cannot be seized in the hand and/or be detached from the flat edge by pulling with the hand, * a protective covering sheet (or film) (4) of adhesive plastic also arranged on that face of the transparent container which is equipped with flat edges, this sheet adhering to the previous permeable sheet by gluing and being capable of being seized in the hand and/or detached from the flat edge by pulling with the hand, * an insecticidal composition (2), and/or a composition which repels insects, this composition comprising an essential oil mixed with a diffusion adjuvant.   <IMAGE>
Patent PT-752149-E (PT)
Inventor: MCARE FINLAY
IPC: G06F21/10
Filed: 1995-03-23
Abstract: Method of controlling the playing of a compact disc on a compact disc player, characterized in that the method comprises the following steps:   reading software instructions indicating the location where the compact disc is to be played from the compact disc,     and in response to a request that the compact disc be played,   operating the compact disc player in accordance with a control program to compare a code provided by the compact disc player with the software instructions to correspondingly at least partly enable or disable the playing of the compact disc.   Compact disc player for controlling the playing of a compact disc on the compact disc player and a compact disc for use in the compact disc player.
Patent PT-798298-E (PT)
Inventor: ISHIHARA SADAO
IPC: A61P9/10
Filed: 1995-12-13
Abstract: Thiazolidinone compounds having the general formula: <CHEM> Äwherein W represents a sulfur atom or an oxygen atom, and X represents a group having the formula: -N(R<1>)-; or   X represents a sulfur atom or an oxygen atom, and W represents a group having the formula: -N(R<1>)-; R<1> represents a hydrogen atom, an alkyl group or a substituted alkyl group; R<2> and R<3> may be the same or different and each represents a hydrogen atom, an alkyl group, a substituted alkyl group, an aryl group or a 5- or 6-membered aromatic heterocyclic group; R<4> represents a hydrogen atom, an alkyl group or a substituted C1-C4 alkyl group; R<5> represents a substituted cycloalkyl group optionally containing a nitrogen atom Äsaid substituent is essentially a group having the formula: -B-ONO2 (wherein B represents a single bond or an alkylene group) and optionally an alkyl groupÜ; and A represents a single bond or an alkylene group; Ü or pharmacologically acceptable salts thereof.  ÄEffectÜ   The compounds have an excellent anti-angina pectoris action and are useful as a therapeutic or preventing agent for angina pectoris.
Patent PT-738682-E (PT)
Inventor: BALLESTRAZZI ARIS
IPC: B65H5/12
Filed: 1996-02-03
Abstract: A device for rapidly feeding sheet inserts to a pusher conveyor of a packaging machine comprising upstream of said device a feeder for feeding sheet inserts one after another in a direction essentially perpendicular to said pusher conveyor, comprising at least one rotary disc provided with at least one element for gripping the sheet insert, the at least one gripping element (26) being operable selectively to lock the sheet insert onto the disc and drag the sheet insert from a position aligned with the insert feeder to an advanced position on the pusher conveyor by causing the sheet insert to undergo a rototranslational movement, the relative drive means for the disc, for the sheet insert feeder and for the pusher conveyor being correlated in their movement. <IMAGE>
Patent PT-778207-E (PT)
Inventor: BALLESTRAZZI ARIS
IPC: B26D7/26
Filed: 1996-11-07
Abstract: A cutting device for trimming printed paper packages in a packaging machine comprising a cutting unit consisting of an upper part (15) and a lower part (16), at least one of the two parts (15, 16) being movable upwards and downwards on passage of a continuous papery material (12) originating from a reel and of flat tubular form bonded transversely and possibly longitudinally by glue and provided with printed portions (10) separated by a neutral strip (29). One (15) of the two parts (15, 16) of the cutting unit carries two blades (25) spaced apart by a distance similar to the width of the strip, which interact with two counter-blades (45) arranged on the other part (16), elastic presser elements (36) being positioned on at least one (15) of the parts of the cutting unit to act to lock the papery material (12) during the cutting action on the strip, removable elements (27) being provided to vary the distance between the blades and counter-blades (45) as the width of the strip (29) varies. <IMAGE>
Patent PT-768083-E (PT)
Inventor: JOHNSON BRIAN F
IPC: A61P9/08
Filed: 1996-07-03
Abstract: A method of treating post myocardial infarction human patients comprising administering to such patients the compound (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthal enamine, also known by the generic name sertraline, or a pharmaceutically acceptable salt thereof.
Patent PT-837854-E (PT)
Inventor: KORNBERG BRIAN EDWARD
IPC: A61P9/08
Filed: 1996-05-13
Abstract: A novel series of substituted quinoxaline 2,3-diones useful as neuroprotective agents are taught. Novel intermediates, processes of preparation, and pharmaceutical compositions containing the compounds are also taught. The compounds are glutamate antagonists and are useful in the treatment of stroke, cerebral ischemia, or cerebral infarction resulting from thromboembolic or hemorrhagic stroke, cerebral vasospasms, hypoglycemia, cardiac arrest, status epilepticus, perinatal asphyxia, anoxia, Alzheimer's, Parkinson's, and Huntington's diseases.
Patent PT-851806-E (PT)
Inventor: JAERVENKYLAE JYRI
IPC: B29C65/14
Filed: 1996-09-20
Abstract: A method of socketing a pipe of oriented plastic having an annular groove inside the socket. An end portion (15) of the pipe is pushed onto a cylindrical mandrel element (11) and the region (l1) of the end portion at the opening thereof where the groove is to be located is heated to a temperature above the glass transition temperature of amorphous plastic and the crystalline melting point of crystalline plastic, respectively. The rest of the end portion is maintained at a temperature below the glass transition temperature or the crystalline melting point, respectively. The end portion (15) when said region is at a temperature above the glass transition temperature or the crystalline melting point, respectively, is pushed onto a second mandrel element (13) axially aligned with said first mandrel element the bottom portion of the socket being formed by said second mandrel element (13). The rest of the end portion is expanded to form the bottom portion of the socket. The end portion of the pipe is cooled and is then withdrawn from the mandrel elements.
Patent PT-841112-E (PT)
Inventor: DAMASSE JEAN-MICHEL
IPC: B22D11/06
Filed: 1997-10-31
Abstract: A detection method of continuous casting between rolls of steel products comprises measuring continuously the roll separation strain (RSF) and a signal representative of the variations in this strain (RSF) generated as a function of time. The signal is used to act upon the roll separation to compensate for any untrue roundness of the rolls. During these measurements the signal is separated into different harmonic components and the resulting comparison of the harmonic components thus obtained with some reference harmonics is representative of the state of defects in the rolls. This state of defects in the rolls allows the definition of different rules for conducting the casting process as a function of the gravity of the roll defects measured.
Patent PT-814975-E (PT)
Inventor: CORNILS GERD
IPC: B60J10/86
Filed: 1997-01-22
Abstract: An assembling element, particularly for vehicle bodywork, is provided with a fastening edge (14) onto which an elastic weatherstrip made from an extrusion-compatible elastomer is extruded. The fastening edge (14) is provided with anchoring notches (17). In a variant, the elastomer of the weatherstrip and the surface of the fastening edge (14) do not form a mutual adhesive joint and the anchoring notches (17) are provided so that the weatherstrip, which is anchored solely mechanically, can be detached if required from the fastening edge (14) and, without further processing, subsequently be refastened mechanically to the fastening edge. In a second variant, the anchoring notches (17) prevent play and make it possible substantially to enhance the connection between the strip and the edge.