baber/WOPTO huggingface dataset:
Patent PT-2000535-E (PT)
Title: Circovirus sequences associated with porcine wasting disease (pwd)
Inventor: JESTIN ANDRÉ
IPC: C12N5/02
Filed: 1998-12-04
Abstract: Nucleotide sequence comprising a 1759 bp genomic DNA sequence (I) of a porcine circovirus called MAP ("maladie de l'amaigrissement du porcelet"; piglet fatal wasting disease), is new. Also claimed are: (1) The nucleotide sequence of the porcine circovirus is: (a) a fragment of (I); (b) a nucleotide sequence homologous to the nucleotide sequence of (a); (c) a nucleotide sequence complementary to (I) or complementary to the nucleotide sequence of (a) or (b); (d) a nucleotide sequence capable of hybridizing under stringent conditions to the nucleotide sequence of (a), (b) or (c); (e) a nucleotide sequence comprising (I) or the nucleotide sequences of (a), (b), (c) or (d); (f) a modified nucleotide sequence comprising the nucleotide sequence of (a), (b), (c), (d) or (e). (2) polypeptide encoded by the nucleotide sequence of (1); (3) cloning and/or expression vectors containing the nucleotide sequences; (4) viral or pseudoviral particles generated from the vectors; (5) host cells transformed with the vectors or (pseudo)viral particles; (6) animals containing the transformed cells; (7) synthetic polypeptides obtained using the amino acid sequence of a polypeptide as in (1); (8) hybrid polypeptides comprising at least one sequence of a polypeptide as in (2) or (7) and a sequence of an immunogenic polypeptide; (9) nucleotide sequences encoding the hybrid polypeptides; (10) vectors containing a sequence as in (9); (11) a method for the detection of the porcine circovirus; (12) mono- or polyclonal antibodies or their fragments or chimeric antibodies capable of specifically recognising a polypeptide as in (2) or (7); and (13) compounds that are capable of binding to a polypeptide or nucleotide sequence as above or of recognising an antibody as in (12) and/or of modulating, inducing or inhibiting the expression of genes and/or of modifying the cellular replication of MAP circovirus or of inducing or inhibiting pathologies associated with MAP circovirus infection in pigs and are capable of being selected by a screening assay comprising contacting a compound with a polypeptide, nucleotide sequence or transformed cell as above or administering the compound to an animal as in (6) and determining the effect of the compound.
Patent PT-2120999-E (PT)
Title: Pharmaceutical compositions comprising activin-actriia antagonists and use thereof in preventing or treating multiple myeloma
Inventor: KNOPF JOHN
IPC: A61K38/18
Filed: 2008-02-01
Abstract: In certain aspects, the present invention provides compositions and methods for promoting bone growth and increasing bone density, as well as for the treatment of multiple myeloma.
Patent PT-2209319-E (PT)
Title: Video encoder
Inventor: DESHPANDE SACHIN GOVIND
IPC: H04N7/26
Filed: 2004-03-26
Abstract: The rate control method for encoded digital video data using a buffer model is described. In the prior art, it is difficult to prevent underflow of the buffer when the random access decoding is done. In the present invention, control parameters such as initial decoder buffer fullness and initial delay are provided at each random access point in the bitstream so that the buffer underflow does not occur and it enables to achieve an optimal decoding delay.
Patent PT-607793-E (PT)
Inventor: WALTER HEINZ
IPC: B23Q39/04
Filed: 1994-01-05
Abstract: A rotating machine tool has a work carrier (1) which can be indexed by a stepping drive and can be locked in fixed angular positions corresponding to individual work stations. Arranged in the individual work stations are work units (22) which each carry at least one work spindle (38). Work fixtures (10) with planetary axes (11) lying in at least one horizontal plane (12) are mounted on the work carrier, the planetary axes running tangentially at a radial distance from the vertical indexing axis (6) of the work carrier and in each case being orientated in pairs parallel to one another. <IMAGE>
Patent PT-675936-E (PT)
Inventor: WALKER THAD O
IPC: C09K8/20
Filed: 1993-11-09
Abstract: The invention provides a water base drilling fluid having decreased swelling effect on hydratable shales contacted by the drilling fluid wherein the aqueous phase contains an alkyl glucoside solubilized therein. Another embodiment of the invention provides an aqueous solution for addition to drilling fluids to decrease the swelling of hydratable shales contacted by the drilling fluid, the solution comprising an aqueous phase having dissolved (solubilized) therein from about 50% to about 85% by weight methyl glucoside and at least about 2% by weight of an alkali metal hydroxide.
Patent PT-721042-E (PT)
Inventor: DICKEDUISBERG INGOLF
IPC: E05D3/06
Filed: 1995-12-23
Abstract: A trunnion (4) on a support (3) slides and turns in a curved track (2) in a track support (1). A further trunnion (4a) on the latter works in a second curved track (2a) in the trunnion support, so that positive opposite guides are formed. When the supports are in the starting position, the trunnions working in the tracks can be at the ends of the latter furthest from the trunnions on the supports themselves. One of the tracks can be straight, and the other curved to a predetermined radius. There can be a trunnion-insertion opening in each track, at right angles to the track itself.
Patent PT-787007-E (PT)
Inventor: BECK LEE R
IPC: A61K35/54
Filed: 1995-09-08
Abstract: The invention relates to an anti-inflammatory factor isolated from milk, methods of purifying the anti-inflammatory factor resulting in substantially or highly purified preparations and to methods for using this factor to remove adhered neutrophils from endothelial cells, to prevent the emigration of cells from the vasculature and to suppress the response of lymphocytes to foreign antigens.
Patent PT-771818-E (PT)
Inventor: JONCZYK ALFRED
IPC: C07K14/75
Filed: 1996-09-10
Abstract: Biotin derivs. of formula (I), opt. (where appropriate) in D- or L-form, and their salts are new, where Q is absent, or is NH-(CH2)n-CO or NH-(CH2)n-NH; R<1> = X-Arg-Gly-Asp-Y, A-Cys(R<2>)-B-U or cyclo-(Arg-Gly-Asp-Z), Z being attached in the side chain of Q or (where Q is absent) to biotin; X, Y = an amino acid residue or a di-, tri-, tetra- or pentapeptide residue, the amino acids being selected from Ala, Asn, Asp, Arg, Cys, Gln, Glu, Gly, 4-halo-Phe, His, homo-Phe, Ile, Leu, Lys, Met, Nle, Phe, Phg, Pro, Ser, Thr, Trp, Tyr and Val and their derivs.; A is absent, or is Asp or a peptide fragment selected from Ala-Asp, Thr-Ala-Asp, Lys-Thr-Ala-Asp, Lys-Thr-Ala-Asn, Lys-Thr-Gly-Asp, Lys-Ala-Ala-Asp, Arg-Thr-Ala-Asp, Ser-Ala-Asp, Gln-Ser-Ala-Asp, Glp-Ser-Ala-Asp, Gly-Lys-Thr-Ala-Asp, Asn-Gly-Lys-Thr-Ala-Asp, Ile-Ser-Ala-Gly, Arg-Ser-Ala-Gly, Cys-Asn-Gly-Lys-Thr-Ala-Asp, Tyr-Cys-Asn-Gly-Lys-Thr-Ala-Asp, Asp-Tyr-Cys-Asn-Gly-Lys-Thr-Ala-Asp, Asp-Asp-Tyr-Cys-Asn-Gly-Lys-Thr-Ala-Asp, Gly-Lys-Thr-Cys(Trt)-Asp, Met-Asp-Asp-Tyr-Cys-Asn-Gly-Lys-Thr-Ala-Asp or Asp-Met-Asp-Asp-Tyr-Cys-Asn-Gly-Lys-Thr-Ala-Asp; B is (i) absent, (ii) OH, Ala, Asn, Asp, Arg, Cys, Gln, Glu, Gly, 4-halo-Phe, His, Ile, Leu, Lys, Met, Orn, Phe, Pro, Ser, Thr, Trp, Tyr, Val or an N-methylated deriv. of these, or (iii) a peptide fragment selected from Pro-Arg, Pro-Arg-Asn, Pro-Arg-Asn-Pro, Pro-Arg-Asn-Pro-His, Pro-Arg-Asn-Pro-His-Lys, Pro-Arg-Asn-Pro-His-Lys-Gly, Pro-Arg-Asn-Pro-His-Lys-Gly-Pro, Pro-Arg-Asn-Pro-His-Lys-Gly-Pro-Ala or Pro-Arg-Asn-Pro-His-Lys-Gly-Pro-Ala-Thr; R<2> = H, 1-6C alkyl, Trt, Dpm or Bzl; U = OH, OR<9>, NH2, NHR<9> or N(R<9>)2; Z = an amino acid residue or a di, tri- or tetrapeptide residue, the amino acids being selected from Ala, Asn, Asp, Arg, Cys, Gln, Glu, Gly, His, Ile, Leu, Lys, Met, Phe, Pro, Ser, Thr, Trp, Tyr, Val and M and derivs. of these, where the amino acid residues are linked together in peptide fashion via the  alpha -amino and  alpha -carboxy gps.; provided that an amino acid residue M is always present; M = the residue of an amino acid of formula NH(R<8>)-CH(R<3>)-COOH; R<3> = a gp. -R<5>-R<4>, -R<6>-R<4> or -R<7>-R<4>; R<4> = OH, NH2, SH or COOH; R<5> = 1-6C alkylene; R<6> = 7-14C alkylenephenyl; R<7> = 8-14C alkylenephenylalkylene; R<8> = H, 1-6C alkyl or 7-12C alkylenephenyl; R<9> = 1-6C alkyl; halo = F, Cl, Br or I; n = 1-10; Glp = pyroglutamic acid; Phg = phenylglycine; Trt = trityl; provided that when R<1> is a gp. A-Cys(R<2>)-B-U, then only one of A and B may be absent.
Patent PT-825848-E (PT)
Inventor: JONES RICHARD E
IPC: A61K47/42
Filed: 1996-04-26
Abstract: Disclosed are translucent proteinaceous compositions comprising collagen and an effective amount of a compatible cytotoxic drug which compositions are characterized by having a single collagen transition temperature of less than about 45 DEG  C. Such compositions possess enhanced retention of the cytotoxic drug at the site of injection and are optically translucent.
Patent PT-977476-E (PT)
Inventor: PETTERSON TORBJORN KARL INGEMA
IPC: A01J5/08
Filed: 1997-11-04
Abstract: A teatcup liner (1) which is intended for being mounted in a teatcup shell (2) comprises a tubular head portion (4) forming a passage for receiving a teat. The passage extends between a first and a second axial end of the tubular head portion. The tubular head portion has an annular lip (8), which in the mounted as well as the non-mounted state of the teatcup liner (1) extends radially inwardly from the tubular head portion. Furthermore, the teatcup liner comprises a tubular shaft portion (5), which extends from a second axial end (7) of the head portion, and a member (14), which is arranged to provide a radially outwardly directed pretension in the lip in the mounted as well as the non-mounted state of the teatcup liner (1), and is located outside said passage. A method of manufacturing such a teatcup liner comprises the steps of moulding the teatcup liner, expanding the head portion, and providing the pretensioning member.
Patent PT-894268-E (PT)
Inventor: RENAULT FRANCOIS
IPC: C10L10/12
Filed: 1997-04-09
Abstract: PCT No. PCT/FR97/00627 Sec. 371 Date Feb. 25, 1999 Sec. 102(e) Date Feb. 25, 1999 PCT Filed Apr. 9, 1997 PCT Pub. No. WO97/39349 PCT Pub. Date Oct. 23, 1997A C.F.R. engine (26) is alternately supplied with a fuel being manufactured (22), sampled from the discharge line of the mixer and, through a line (24), with a reference product (25) of which the cetane number is known, by two separate supply circuits (22, 24) each having a high pressure fuel pump (33, 34), the C.F.R. engine (26) operating at a constant compression ratio.
Patent PT-890541-E (PT)
Inventor: HAKALA HARRI
IPC: B66B7/00
Filed: 1994-06-27
Abstract: The traction sheave elevator comprises an elevator car (1) moving along elevator guide rails (10), a counterweight (2) moving along counterweight guide rails (11), a set of hoisting ropes (3) on which the elevator car and the counterweight are suspended, and a drive machine unit (6) comprising a traction sheave (7) driven by the drive machine and engaging the hoisting ropes (3). The drive machine unit (6) of the elevator is placed in the top part of the elevator shaft (15) and in the horizontal cross-section of the shaft between the vertical projection of the cabin and the shaft wall, whereby the drive machine unit is fixed to a wall or the ceiling of the elevator shaft.
Patent PT-975545-E (PT)
Inventor: REGAN PHILIP MALCOLM
IPC: B65H49/08
Filed: 1998-04-17
Abstract: An article of manufacture which comprises a material for sealing threaded pipe joints comprising a multifilament yarn (7) ready-coated with a joint sealing composition and packaged in a dispenser (1) from which the coated yarn may be supplied for direct application to a threaded area of a pipe. The dispenser comprises a hollow body (1), a cap portion (13) having a dispensing aperture (16) therein and closure means (14) for closing over the aperture when the dispenser is not in use and a multifilament yarn (7) ready-coated with a pipe-joint sealing composition is contained in the body. Suitably, the sealing composition is a non-curing paste composition which comprises an oil and filler, optionally with other ingredients, the oil being selected from linseed oil, silicone oils and mineral oils. Suitably, the yarn is of polyamide or polypropylene.
Patent PT-1018017-E (PT)
Inventor: HUCHZERMEIER ROY
IPC: G01N33/569
Filed: 1998-09-23
Abstract: The invention disclosed herein presents an antigen-capture immunoassay that utilizes serum, plasma, milk, urine, saliva, or other bodily fluid samples to identify cattle infected with the Bovine Viral Diarrhea Virus (BVDV). The results of this assay allow an effective, reliable, quick, and cost efficient way to identify, and thereby remove, infected cattle and/or other ruminants from otherwise uninfected herds. The BVD virus causes an acute enteric disease with a variety of clinical manifestations, and is closely related to sheep border disease virus (BDV) and hog cholera virus (HCV). The traditional method of detecting infected animals, including persistently infected (PI) carriers, has been through .the .use of virus isolation procedures. While .this older test methodology can detect infected animals, the virus isolation test can only be performed by highly trained technicians in a highly specialized laboratory facility. The kit disclosed herein uses ELISA methodology, employs the BVDV antigen specific monoclonal antibody 15.c.5, and requires at least 100  mu l of sample per assay.
Patent PT-1045802-E (PT)
Inventor: JARDINE MARK HAMILTON
IPC: B65D88/22
Filed: 1999-01-06
Abstract: A collapsible bag (2) for the storage and transport of bulk materials comprises a bottom panel (13), a plurality of side panels (11, 12), and a pair of substantially parallel tubular guide members (4). The guide members (4) are secured on or adjacent to the tops of at least some of the side panels (11, 12). The tubular members (4) are resilient and connected together by rigid spacing means (22) at or adjacent to their ends. The invention also provides a method for manufacturing the bag and a device for modifying a conventional bag to make a bag in accordance with the invention.
Patent PT-1086082-E (PT)
Inventor: CALDWELL WILLIAM SCOTT
IPC: A61K31/44
Filed: 1999-06-03
Abstract: Compounds incorporating aryl substituted olefinic amine are provided. Representative compounds are (4E)-N-methyl-5- (3-pyridyl) -4-penten-2-amine, (4E) -N-methyl-5- (5-pyrimidinyl) -4-penten-2-amine, (4E)-N-methyl-5-( 5-methoxy-3-pyridyl) -4-penten-2-amine, (4E)-N- methyl-5- (6-amino-5-methyl -3-pyridyl)-4-penten -2-amine, (2R)-(4E) -N-methyl-5-(3-pyridyl) -4-penten-2-amine, (2R)-(4E)-N- methyl-5-(5- isopropoxy-3-pyridyl) -4-penten-2-amine, (4E)-N-methyl -5-(5-bromo-3-pyridyl) -4-penten-2-amine, (4E)-N-methyl -5-(5-ethoxy-3- pyridyl)-4-penten- 2-amine, (2S)-(4E)-N- methyl-5-(3-pyridyl) -4-penten-2-amine, (4E)-N-methyl -5-(5-isopropoxy-3- pyridyl)-4- penten-2-amine and (2S)-(4E)-N-methyl -5-(5-isopropoxy -3-pyridyl) -4-penten-2-amine.
Patent PT-1137798-E (PT)
Title: A method of isolating stem cells
Inventor: SMITH CLAYTON A
IPC: C12Q1/02
Filed: 1999-12-07
Abstract: The present invention relates, in general, to stem cells, and in particular, to a method of isolating stem cells and to reagents suitable for use in such a method. The invention further relates to stem cell populations isolatable in accordance with the present method.
Patent IE-790094-L (IE)
Title: Ergot alkaloid derivatives
IPC: C07D519/02
Filed: 1979-01-30
Abstract: This invention provides compounds of <IMAGE> I wherein R1 is benzyl or benzyl substituted by hydroxy, chlorine, fluorine, amino, amido, (C2-5) alkanoylamino, (C1-4) alkyl, (C1-4) alkylamino, (C1-4) alkoxy, (C1-4) alkylamido, di[(C1-4) alkyl]amino, or di[(C1-4) alkyl]amino, R2, R4 and R5 are each (C1-4) alkyl, and R3 is (C2-4) alkyl are prolactin secretion promoters.
[US4609657A]
Patent IE-35580-L (IE)
Title: Pressure-sensitive recording paper.
IPC: B41M5/165
Filed: 1971-02-24
Abstract: 1292939 Microcapsules FUJI PHOTO FILM CO Ltd 19 April 1971 [27 Feb 1970] 22762/71 Heading C3R [Also in Divisions B8 and D2] Microcapsules for use in pressure-sensitive recording paper are prepared by dissolving a single wall-forming material capable of forming, or two or more wall-forming materials capable of reacting to form, a polymeric compound which is insoluble in both oil and water, in an oily liquid (defined) containing a colour-former and a first carrier solvent (defined) to prepare a solution, emulsifying the solution in a second solvent, which is a polar solvent, forming a continuous phase and miscible with the first solvent elevating the temperature of the emulsified system to transfer the wall-forming material or materials to the surface of the oil drops and to cause the wall-forming material or materials to form the polymeric compound on the surfaces of the oil drops, thereby producing the microcapsules containing the colour-former. Suitably, a catalyst to promote the wall-forming reaction is incorporated in the solution. It is preferred to use as the wall-forming materials a polyisocyanate or polyisothiocyanates and a polyamine, polycarboxylic acid, acid anhydride epoxy compound, polyol, polysulphide, lactone or lactam. Numerous solvents are listed for forming the solution. Water is the preferred second solvent. Protective colloids or surfaceactive agents may be used to emulsify the oily liquid. Examples of colour formers are triphenylmethane compounds, diphenylmethane compounds, xanthene compounds, thiazine compounds and spiropyran compounds. The oily liquid is any liquid capable of being emulsified to formliquid drops in and immiscible with the second polar solvent, with the use of a surface-active agent or protective colloid, if necessary, andis suitably a chlorinated diphenyl, chlorinated paraffin, cotton seed oil, peanut oil, silicone oils, tricresyl phosphate, monochlorobenzene, kerosene, n-paraffins or iso-paraffins. In a typical example, crystal violet lactone is dissolved in a mixture of chlorinated diphenyl and kerosene and to the solution is added bisphenol A dissolved in a mixed solvent of acetone/ methylene chloride, xylylene diisocyanate and dibutyl tin laurate as catalyst. The resulting solution is poured into an aqueous solution of gum arabic with stirring to form an emulsion, followed by the addition of more water and heating to bring about the encapsulation. After cooling a styrene-butadiene latex, sodium alginate and cellulose powder is added as a binder to complete the preparation of a micro-capsule solution which may be applied to a support paper for use as a pressure-sensitive recording paper (see Divisions D1-D2).
[GB1292939A]
Patent IE-40585-L (IE)
Title: (naphthoylamino-alkylphenoxy)-alkyl-carboxylic acid¹derivatives
IPC: C07C233/87
Filed: 1975-02-05
Abstract: 1449586 4<SP>1</SP>-(Naphthoylaminoalkyl)-phenoxyacetic acids and esters BOEHRINGER MANNHEIM GmbH 3 Feb 1975 [6 Feb 1974] 4483/75 Heading C2C Novel compounds I in which R 1 and R 2 are H or C 1-3 alkyl, Z is OH or C 1-3 alkyl and n is 1 or 2 and their salts when Z is OH are prepared by reacting 4-(aminomethyl or -ethyl)-phenol (II) or a reactive derivative thereof simultaneously or successively with 1- or 2-naphthoic acid (III) or a derivative thereof and a compound (IV) X-CR 1 R 2 -COZ in which X is a radical derived from an anion of a hydrohalic or sulphonic acid and, when the aminophenol is reacted successively with the other two components, the amino or hydroxy group of compound (II) is blocked by a protecting group which is removed after the first stage to allow the second stage to be carried out. Compounds I (R 1 , R 2 =C 1-3 alkyl) are also prepared by using a mixture of R 1 COR 2 , CCl 3 and an alkali metal hydroxide in place of compound (IV). The free acids are also obtained by hydrolysis of the corresponding esters and other esters may be obtained by transesterification. N - (4 - Hydroxyphenyl - methyl or -ethyl) - 2- naphthamides are prepared by hydrolysis of N- [4 - (2 - naphthoyl - oxy)phenyl - methyl or -ethyl]- 2-naphthamides which are prepared by reacting 2-naphthoyl chloride with an aminophenol (II). Compounds I lower serum lipid and cholesterol levels and form with a carrier or diluent a pharmaceutical composition which may be administered orally or parenterally.
[GB1449586A]
Patent IE-850311-L (IE)
Title: Determination of micro-organisms
IPC: C12M1/28
Filed: 1985-02-08
Abstract: The present invention provides a device for the determination of micro-organisms, comprising a vessel (1) closable with a cover (3) in which vessel is housed a nutrient medium carrier in the form of a longitudinal carrier body (2, 40) which has a plurality of troughs (10, 11, 12, 13, 41, 42, 45, 46) for the reception of nutrient substrate substances, the upper surfaces of which are provided with a removable cover, wherein at least one closable filler connection (19, 20, 43, 44), formed on the carrier body (2, 40) opens into each trough (10, 11, 12, 13, 41, 42, 45, 46).
Patent IE-880375-L (IE)
Title: Azole derivatives, useful in controlling plant diseases and¹regulating plant growth
IPC: C07C69/74
Filed: 1988-02-11
Abstract: The method for preparing azole derivatives (I) R1 and R2 =(C1-C5) alkyl or hydrogen; X=halogen atom, (C1-C5) alkyl or phenyl group; n=0-2; A=nitrogen atom or (H) having plant blight inhibition and growth control comprises: (a) adding 44.8g of methyl 1-(4- chlorobenzyl)-3,3-dimethyl-2-oxycyclopentane carboxylate to 120ml of bromic acid and agitating at 100≦̸C for 12 hrs.; (b) cooling the reaction mixtures and extracting with ethylacetate to obtain organic layer; (c) washing organic layer with sodium bicarbonate solution and drying.
[KR900003269B1]
Patent IE-880682-L (IE)
Title: Adhesive dressing
IPC: A61M25/02
Filed: 1988-03-09
Abstract: A dressing for retaining a cannula on the skin is described. The dressing comprises a backing film coated on one face with an adhesive layer and with first and second release sheets covering the adhesive layer. A hole and a dividing line are cut through the dressing and second release sheet so that the dividing line extends from the hole to one edge of the dressing and the edge of the second release sheet. In use when the second release sheet is removed the hole in the dressing fits around the indwelling cannula. In a preferred form a portion of the dressing comprises an adhesive coated handle which is stiffer than the remainder of the dressing and which carries the hole and dividing line.
Patent IE-850995-L (IE)
Title: Partial aminoacid sequences of human gamma interferon
IPC: C12P19/34
Filed: 1985-04-18
Abstract: Partial sequences of human- gamma -interferon, comprising aminoacid sequences 5 to 127, 1 to 127 and 5 to 146, having biological activity. These partial sequences can be obtained by a genetic engineering process, for which purpose the appropriate DNA sequences are chemically synthesized. The DNA sequences are incorporated in hybrid plasmids, and the latter are introduced into host organisms and their expression is induced there. The biologically active polypeptides are suitable, as is human- gamma -interferon, for medicaments.
Patent FI-811345-L (FI)
Inventor: SIEKE HELMUT
IPC: C02F1/34
Filed: 1981-04-29
Abstract: Process and apparatus for treating material by applying non-sinusoidal vibrations. In apparatus for separating solids from the liquid phase of a dispersion, non-sinusoidal vibration is applied by vibrating at least a portion of a wall of a receptacle for the dispersion or by a vibrating plate, a pair of vibrating plates or a hollow body in the receptacle. In a roller mill for crushing material one of the rollers is vibrated axially relative to the other. In a juice press a vibrating plate is provided at the bottom of the press cylinder. In a jaw crusher, one of the jaws is vibrated in a direction parallel to the face of the jaw. In a ball mill comprising a cylinder rotating on a horizontal axis, the cylinder is vibrated in an axial direction. Non-sinusoidal vibration is produced by a hydraulic servomotor fed with pulses of hydraulic pressure fluid by a rotary control valve.