baber/WOPTO huggingface dataset:
Patent AU-690244-B2 (AU)
Title: Method and device for detection of specific target cells in specialized or mixed cell populations and solutions containing mixed cell populations
Inventor: FODSTAD OYSTEIN
IPC: G01N33/569
Filed: 1995-03-10
Granted: 1998-04-23
Abstract: The invention relates to a method and apparatus for detecting specific target cells in a simple and time-saving way, using paramagnetic particles, antibodies recognizing the Fc portions of target-cell associating antibodies and target-cell associating antibodies directed to specific antigen determinants in the target-cell membranes. Incubation of the cell suspension with detergent and/or second antibodies or antibody fragments, prelabeled or not with fluorescent agents, metallocolloids, radioisotopes, biotin complexes or certain enzymes allowing visualization, dramatically increase the specificity of the method. The method and apparatus described provides a solid support and permanent record which is easily viewed by microscopy, permits viewing and quantification of the whole specimen rather than small fractions thereof and allows the use of large specimen volumes to be analysed, the device may also be scanned automatically by conventional densitometric technology. The method and apparatus can be used for isolation of the target cells by magnetic field application, and a kit and apparatus for performing the method according to the invention is described.
Patent AU-728713-B2 (AU)
Title: Therapeutic agents for asthma
Inventor: UCHIDA YOSHIYUKI
IPC: A61K31/167
Filed: 1997-01-27
Granted: 2001-01-18
Abstract: The description relates to a therapeutic agent which comprises as the active agent a compound given by the formula (1) and/or (1') and/or a pharmaceutically acceptable salt thereof. The agent of the invention exhibits great effectiveness in cases of both immediate and later asthmatic reactions, especially the latter. Owing to its low toxicity, the agent of the invention can safely be prescribed for human beings.
Patent AU-702421-B2 (AU)
Title: Stop-cock valve
Inventor: WALKER CLARENCE LOGAN
IPC: A61M39/22
Filed: 1995-04-17
Granted: 1999-02-18
Abstract: The present invention relates to a stop-cock valve (10) useable in conjunction with a fluid delivery set for delivering fluids such as intravenous fluids or enteral fluids from one or more containers to a patient. The valve (10) comprises a rotatable stem (13) which includes a V-shaped fluid flow passage (21) comprising a first arm (22) and a second arm (23) which have a convergence at (24).
Patent AU-621310-B2 (AU)
Title: Immunometric assay kit and method applicable to whole cells
Inventor: CARRIERE DOMINIQUE
IPC: G01N33/543
Filed: 1988-09-29
Granted: 1992-03-12
Abstract: A kit for the assay of the surface antigens characteristic of a cell population or subpopulation comprising, as components: a) a solid support on which are fixed by covalent bonding or by physical adsorption one or more monoclonal antibodies directed against the surface antigens of the cellular population to be assayed; b) one or more solutions, each containing a monoclonal antibody specific for the cell population or subpopulation to be assayed, labelled with a radioisotope probe or an enzyme probe; c) in the case of antibodies marked with an enzyme probe, one or more solutions contributing the necessary reagents (substrate and chromogen) for detecting the enzyme activity. The invention also relates to a process for immunometric assay of the surface antigens of a cell population or subpopulation. The assay kit and the immunometric process according to the invention can be employed for the total assay of the population of T lymphocytes and/or of the subpopulations of T4 and T8 lymphocytes.
Patent AU-773922-B2 (AU)
Title: Improved methods for insertion of nucleic acids into circular vectors
Inventor: ROMANTCHIKOV YURI
IPC: C12N15/66
Filed: 1999-12-17
Granted: 2004-06-10
Abstract: The present invention provides vectors and methods which improve the efficiency of nucleic acid insertion into circular vectors, which generally facilitate nucleic acid cloning and specifically facilitate the preparation of DNA libraries. In general, the present invention involves separation of the cloning process into two distinct steps: (a) insertion which is done at a high nucleic acid concentration favoring intermolecular joining, and (b) circularization which is performed at a low nucleic acid concentration favoring intramolecular circularization. The present vectors generally have distinct insertion ends and circularization ends which are blocked from covalent joining during the insertion step. Circularization ends contemplated by the present invention include complementary cohesive ends and topoisomerase-linked ends. The present vectors and methods allow minute amounts of nucleic acid inserts to be efficiently cloned. Moreover, little or no insert size selection occurs with the present methods so that large as well as small nucleic acid inserts are readily inserted into the present vectors. Thus, DNA libraries which are representative of the entire range of size of DNA inserts can be made, and, for example, full length cDNA libraries are readily obtained.
Patent AU-719947-B2 (AU)
Title: Improved chemical process for preparing amide derivatives of antibiotic A 40926
Inventor: PANZONE GIANBATTISTA
IPC: C07K1/02
Filed: 1997-04-15
Granted: 2000-05-18
Abstract: Improved chemical process for preparing the compounds of formula (I), wherein: R1 represents (C9-C12)alkyl; M represents hydrogen, alpha-D-mannopyranosyl or 6-O-acetyl-alpha-D-mannopyranosyl and Y represents an amino group of formula -NR2-alk1-(NR3-alk2)p-(NR4-alk3)q-W. One aspect of the invention refers to the preparation of the intermediate compound of formula (III) (which corresponds to the above compound of formula (I)wherein R1 and M are as above defined and Y is hydroxy), by reacting a compound of formula (II) (which corresponds to the above compound of formula (I) wherein R1 and M are as above defined and Y is hydroxymethyl), with a (C1-C4)alkanol in the presence of a concentrated mineral acid, using the same alkanol as the reaction solvent and submitting the obtained ester compound to a reductive process by adding an alkali metal borohndride into the same reaction mixture. A further aspect of the invention refers to the amidation reaction for obtaining the compound of formula (I), which is carried out by reacting a compound of formula (III) with a suitable amine of formula (IV): NHR3-alk1-(NR4-alk2)p-(NR5-alk3)q-W, wherein R3, R4, R5, alk1, alk2, alk3, p, q and W are as defined in formula (I), in an inert organic solvent, in the presence of a condensing agent and setting the initial pH of the mixture (measured after diluting a sample of the reaction mixture with 9 volumes of water) at a value of from 6.5 to 9.0. By combining the above improved steps into a single process, it is possible to set up a particularly convenient process for preparing the compounds of formula (I). In addition, a purification method involving the use of polyamide resins and aqueous eluents is provided.
Patent AU-650791-B2 (AU)
Title: Imaging agent for diagnosis
Inventor: HASHIGUCHI YUJI
IPC: A61K49/04
Filed: 1992-10-02
Granted: 1994-06-30
Abstract: There is disclosed an imaging agent for diagnosis comprising a compound composed of a polynuclear type compound of the formula I or II: <CHEM> wherein each X is a hydrogen atom or a bifunctional ligand, at least one of them are bifunctional ligand and m or n is an integer of 1 to 6, and at least one metal ion being coordinated with at least one bifunctional ligand moiety, said metal ion being selected from the group consisting of metal ions having the atomic number of 21-29, 31, 32, 37-39, 42-44, 49 and 56-83.
Patent AU-618298-B2 (AU)
Title: System for sea navigation or traffic control/assistance
Inventor: GOUARD PHILIPPE
IPC: G01C21/20
Filed: 1988-12-01
Granted: 1991-12-19
Abstract: The system comprises a reference radionavigation system consisting of beacons (Si, Si + 1) and a central site (M) for fixed or mobile navigation control. The central site and the beams are each equipped respectively with a first means of communication (MI) between the central site and the beacon and with a second means of communication (Mj) between the central site (M) and the vessel (Vj) and, in addition, with a means of communication (Vji) between the source beacon (Si) and the vessel (Vj). The central site (M) also includes a computer (CM) for calculating the distances between the central site (M) and each vessel (Vj) from each reference beacon (Si) and for determining the position of the site (M) and each vessel (Vj) with respect to the reference radionavigation system. A real-time display (TVM) of the position of the vessel (Vj) is provided at least at the central site (M). Application to the management of a flotilla of vessels (Vj), to the monitoring and control of sailing regattas or car race tracks, and to navigational training programmes. <IMAGE>
Patent AU-647318-B2 (AU)
Title: Apparatus for removing the entrails from the abdominal cavity of poultry
Inventor: MEYN CORNELIS
IPC: A22C21/06
Filed: 1992-10-22
Granted: 1994-03-17
Abstract: The invention relates to an apparatus for removing the entrails from the abdominal cavity of poultry suspended with its legs from a suspension conveyor (4) wherein the entrails, after being entirely disconnected, are moved along over some distance synchronously with the poultry by a belt conveyor (11). Transferring the entrails from the eviscerating means (6) towards the belt conveyor (11) occurs through a transferring device (3) preferably comprising a drum rotatable around a vertical axis (8) and being provided with transferring means regularly spaced on its circumference. Two cooperating clamping parts (15,21) movable relative to each other may be applied as each respective transferring means. <IMAGE>
Patent AU-702392-B2 (AU)
Title: Method of regulating immune function
Inventor: CINCOTTA ANTHONY H
IPC: A61K31/165
Filed: 1995-07-07
Granted: 1999-02-18
Abstract: Methods for rectifying or ameliorating abnormal responses of mammalian immune systems is provided. Also provided are methods for modifying normal responses of the mammalian immune system. Further provided is a method for treating a mammal having an immune dysfunction by administering to the mammal a prolactin reducer and/or enhancer at a predetermined time or times during a 24-hour period that results in modification of the mammal's abnormal prolactin profile so that it approaches or conforms to the prolactin profile of a young mammal of the same species, thereby ameliorating said immune dysfunction. Also provided is a method of upregulating or augmenting an immune response in a mammal.
Patent AU-689303-B2 (AU)
Title: (Azetidin-1-ylalkyl)lactams as tachykinin antagonists
Inventor: MACKENZIE ALEXANDER RODERICK
IPC: A61K31/4545
Filed: 1995-07-29
Granted: 1998-03-26
Abstract: PCT No. PCT/EP95/03054 Sec. 371 Date Feb. 10, 1997 Sec. 102(e) Date Feb. 10, 1997 PCT Filed Jul. 29, 1995 PCT Pub. No. WO96/05193 PCT Pub. Date Feb. 22, 1996The present invention provides compounds of formula (I) and the pharmaceutically acceptable salts thereof, wherein R is C3-C7 cycloalkyl, aryl or C1-C6 alkyl, said C1-C6 alkyl, said C1-C6 alkyl being optionally substituted by fluoro, COOH, -COO(C1-C4 alkyl), C3-C7 cycloalkyl, adamantyl, aryl or het1, and said C3-C7 cycloalkyl being optionally substituted by 1 or 2 substituents each independently selected from C1-C4 alkyl, C3-C7 cycloalkyl, C1-C4 alkoxy, hydroxy, fluoro, fluoro (C1-C4) alkyl and fluoro (C1-C4) Alkoxy; R1 is phenyl, naphthyl, thienyl, benzothienyl or indolyl, each optionally substituted by 1 or 2 substituents each independently selected from C1-C4 alkyl, C1-C4 alkoxy, halo and trifluormethyl; R2 is -CO2H, -CONR3R4, -CONR5(C3-C7 cycloalkyl), -NR5(C2-C5 alkanoyl), -NR3R4, -NR5CONR5R6, (C3-C7 cycloalkyl-C1-C4 alkyl)R5N-, -NR5COCF3, -NR5SO2CF3, -NR5(SO2 C1-C4 alkyl), -NR5SO2NR5R6, -NR5(SO2 aryl), -N(aryl) (SO2C1-C4 alkyl), -OR5, -O(C3-C7 cycloalkyl), -SO2NR5R6, het3 or a group of formulas: (a), (b), (c), (d), (e), (f), (g) or (h); X is C1-C4 alkylene; X1 is a direct link or C1-C6 alkylene; X2 is a direct link, CO, SO2, or NR5CO; and m is 0, 1 or 2; together with intermediates used in the preparation of compositions containing and the use as tachykinin angatonists of such derivatives.
Patent AU-771977-B2 (AU)
Title: Media in the form of complex dispersions, method for preparing same and uses
Inventor: DEGERT CORINNE
IPC: A61K8/06
Filed: 2000-03-16
Granted: 2004-04-08
Abstract: The invention concerns novel media in the form of complex dispersions, method for preparing same and their uses. Said media consist of a first medium in the form of droplets wherein is dispersed a phase containing organized double layers of surfactants, preferably in the form of multilamellar vesicles, said droplets being in emulsion in a second medium called continuous phase non-miscible with the first medium. Said media can be used as base for cosmetic compositions. They can contain active principles, in particular for controlling their release and/or protecting and/or controlling their pH. They can also be used to make polymer microspheres containing an active principle. They are also useful as antigen vector.
Patent AU-609969-B2 (AU)
Title: Method of preparing lactulose
Inventor: HAAR WALTERUS T DE
IPC: C07H3/04
Filed: 1989-04-26
Granted: 1991-05-09
Abstract: The invention relates to a new method of preparing lactulose by basic isomerisation of lactose. According to the invention the reaction mixture is treated with hydrogen peroxide or sodium chlorite to obtain lactulose of an acceptable colour for a pharmaceutical product. Preferably 0.5 - 5 g of hydrogen peroxide are used per kg of lactose. 1H2O.
Patent AU-768401-B2 (AU)
Title: Sterile water generator
Inventor: JOSLYN LARRY J
IPC: A61L2/18
Filed: 2001-02-05
Granted: 2003-12-11
Abstract: A sterile water generator (B) generates a stream of sterile water on demand. A water heater (130) heats incoming, unsterile water to a sufficient temperature to achieve sterilization of the water. The sterile water is then passed through a heat exchanger (110) which transfers excess heat from the sterile water to the incoming water. This reduces the energy consumption of the water heater and reduces the temperature of the sterile water ready for use. The sterile water is delivered to a site (A), at which the water is to be used, through a sterile water delivery pathway (C) to avoid recontamination of the water. A first portion (162) of the pathway is pre-sterilized by flowing steam or hot water, generated by the water heater, along the pathway (C). A second portion (212) of the pathway is sterilized with a liquid antimicrobial from the site. The first and second portions of the pathway have at least one common leg (164).
Patent AU-776271-B2 (AU)
Title: Lipoxin compounds and their use
Inventor: SERHAN CHARLES N
IPC: A61K31/047
Filed: 2000-03-14
Granted: 2004-09-02
Abstract: Aspirin (ASA) triggers a switch in the biosynthesis of lipid mediators, inhibiting prostanoid production and initiating 15-epi-lipoxin generation, through the acetylation of cyclooxygenase II.
Patent AU-665321-B2 (AU)
Title: Nozzle for discharging air and method
Inventor: KUKLIK MILAN
IPC: F24F13/14
Filed: 1993-03-17
Granted: 1995-12-21
Abstract: An air discharge nozzle and method for vehicles having a grill (21') which has a high degree of visual opacity to enhance design aesthetics, low impedance to air flow so that the face velocity remains high, and which does not significantly affect directionality of the air as imparted to the air stream by an upstream control mechanism. The grill (21') is comprised of a monolayer of polygonal cells in an array of cells, each cell being bounded by planar walls having a depth "L" interstitial thickness "T" and a diameter or major dimension "D", wherein the interstitial depth L is short enough such that the planar walls do not act as vanes to significantly affect directionality of the air, the interstitial thickness T has a value such that the impedance to air flow is low, and the length to diameter ratio L/D is no greater than about 0.7 and no less than about 0.3, such that the relative visual opacity of the grill when viewed from any angle is high. The open cell area Ao must be at least about 76% of the available (total) area to obtain an acceptable 1800 ft/min face velocity at a blower pressure of 0.24 inches H2O. The upstream directionality control mechanism includes a disc intruder (224). The intruder member has axially projecting control shaft (35') which carries a spherical member (37') frictionally received in a spherical socket (38') such that the control shaft can easily be manually manipulated.
Patent AU-661906-B2 (AU)
Title: 5-amino-2-phenoxysulfonanilide compound
Inventor: YOSHIKAWA KENSEI
IPC: C07C311/08
Filed: 1993-04-21
Granted: 1995-08-10
Abstract: A 5-amino-2-phenoxysulfonanilide compound represented by formula (I) and a salt thereof, having excellent anti-inflammatory, antipyretic, analgesic and antirheumatic effects, thus being useful as anti-inflammatory, antipyretic, analgesic and antirheumatic agents. <CHEM>
Patent AU-699418-B2 (AU)
Title: External straightener for colonoscopy
Inventor: PATERNUOSTO MARIO IMMACOLATO
IPC: A61B1/303
Filed: 1995-11-10
Granted: 1998-12-03
Abstract: The external straightener for colonoscopy has an ovoid shape with a protuberance in proximity to one of the two ends; it is preferably made of rubber, PVC, natural latex or the like and allows the endoscopic examination known as colonoscopy to be performed in a considerably shorter time than the standard times, with a considerably reduction in the discomfort for the patient.
Patent AU-738619-B2 (AU)
Title: Industrial press safety system
Inventor: APPLEYARD ROBERT MEREDITH
IPC: B21D55/00
Filed: 2000-05-05
Granted: 2001-09-20
Abstract: A safety system for an industrial press having a moveable section ( 30 ), the safety means including: a laser emitting means ( 1 ) for emitting a continuous planar laser beam ( 9 ) having a generally constant lateral width; a light receiving means ( 22 ) for receiving the laser beam and for detecting when an object intersects the laser beam; and a control means for stopping or preventing movement of the moveable section of the press when the receiving means detects that the laser beam has intersected an object.
Patent AU-768612-B2 (AU)
Title: Pharmaceutical compositions for the treatment of (helicobacter pylori)-associated disorders
Inventor: CHOWERS MICHAL Y
IPC: A61P31/04
Filed: 1999-06-17
Granted: 2003-12-18
Abstract: The invention relates to pharmaceutical compositions and methods for treating and/or preventing Helicobacter pylori-associated disorders, particularly disorders of the gastrointestinal tract. The pharmaceutical compositions comprise as active ingredient a therapeutically effective amount of a compound which inhibits the growth-enhancing effect of gastrin on H. pylori. The active ingredient may specifically be a compound which is capable of inhibiting gastrin uptake by H. pylori, and/or which is an antagonist of the human or H. pylori gastrin receptor.
Patent AU-651793-B2 (AU)
Title: Writing appliance that closes automatically after a given time-interval
Inventor: WITTEK GOTZ-ULRICH
IPC: B43K24/08
Filed: 1990-02-14
Granted: 1994-08-04
Abstract: A pen with a cap-less closure can be operated by a push-button or other mechanism. For writing, the lead is switched into a locked position of defined instability. When writing ceases, the lead is automatically released after a fixed time-interval. The writing appliance is therefore closed automatically after a predetermined time-interval without the action of other external influences.
Patent AU-568967-B2 (AU)
Title: 2-alkoxycarbonyl alkyl-3-oxo-5,6-diaryl-1,2,4-triazines
Inventor: COUSSE HENRI
IPC: A61P25/04
Filed: 1986-01-28
Granted: 1988-01-14
Abstract: 2-Alkoxycarbonylalkyl-3-oxo-5,6-diaryl-as-Triazines of the formula I <IMAGE>  I  wherein R and R1, which may be identical or different, represent hydrogen, alkyl, alkoxy, hydroxy, dialkylamino, or halogen, R2 represents hydrogen or alkyl, and R3 represents alkyl, the method of preparation thereof, pharmaceutical compositions thereof, and a method of treating therewith, are all disclosed. The compounds are useful as essentially non-antiinflammatory analgesics.
Patent AU-577674-B2 (AU)
Title: Organopolysilazanes
Inventor: LEBRUN JEAN JACQUES
IPC: C08G77/62
Filed: 1986-02-24
Granted: 1988-09-29
Abstract: The present invention relates to a process for the treatment of polysilazane in a homogeneous phase with a catalytically effective quantity of an acid catalyst selected from HClO4 and CF3SO3H. The polysilazane is preferably selected from the group consisting of organopolysilazane, organopoly(disilyl)silazane and mixtures thereof. The organic radicals bonded to the silicon atoms are preferably saturated or aromatic hydrocarbon radicals and the silicon atoms of the polysilazane are substantially free from any hydrogen atom bonded directly to the silicon atoms. The polysilazanes treated in this manner have good thermal behavior and, are particularly useful as precursors of ceramic products.
Patent AU-681611-B2 (AU)
Title: Mechanical process and device for dehumidifying a filter cake
Inventor: BOTT REINHARD
IPC: B01D33/66
Filed: 1993-11-10
Granted: 1997-09-04
Abstract: In a process for mechanically dehumidifying a filter cake, differential pressure causes a treatment fluid to flow through the filter cake. Pressure and temperature on the side of the filter cake which faces the filter surface are set in such a manner that the treatment fluid is present there in its liquid phase, whereas pressure and temperature on the side of the filter cake opposite to the filter surface are set in such a manner that the treatment fluid is present on that side in its gaseous phase.
Patent AU-708324-B2 (AU)
Title: Data transmission system with sliding-window data flow control
Inventor: KANERVA MIKKO
IPC: H04L47/27
Filed: 1996-05-08
Granted: 1999-08-05
Abstract: PCT No. PCT/FI96/00260 Sec. 371 Date Jan. 6, 1997 Sec. 102(e) Date Jan. 6, 1997 PCT Filed May 8, 1996 PCT Pub. No. WO96/36154 PCT Pub. Date Nov. 14, 1996In a digital data transmission system using sliding-window flow control with an adjustable window size on a non-transparent data connection whose nominal data transmission rate may vary during the connection, a receiving party delays the transmission of a retransmission request for a missing frame for the duration of a delay, so that the receiving party may ensure that the missing frame has not been moved to be sent later in the same group or in next groups. If the missing frame is received later in the same group or in the next groups within said delay, no retransmission request is sent. If the missing frame is not received by the end of the delay, a retransmission request is sent. This eliminates unnecessary retransmissions due to the wrong frame order, and resulting loading or congestion. This results in a higher throughput on the data connection. If grouping is not being used, retransmission is not delayed unless a delay is needed for another reason.
Patent AU-720969-B2 (AU)
Title: Oligonucleotide compositions and methods for the modulation of the expression of B7 protein
Inventor: BENNETT C FRANK
IPC: A61K38/00
Filed: 1997-12-16
Granted: 2000-06-22
Abstract: Compositions and methods for the diagnosis, prevention and treatment of immune states and disorders amenable to treatment through modulation of T cell activation are provided. In accordance with preferred embodiments, oligonucleotides are provided which are specifically hybridizable with nucleic acids encoding B7 proteins.