baber/WOPTO huggingface dataset:
Patent CA-2438713-A1 (CA)
Title: Dibenzo[c]chromen-6-one derivatives as anti-cancer agents
Inventor: MERCURE JULIE
IPC: C07D407/04
Filed: 2002-02-21
Abstract: Molecules demonstrating anti-proliferative effects against epithelial cancer cell lines and endothelial cells and methods of synthesis are disclosed. The molecules are intended for use in therapeutic preparations for the treatment of cancer through either anti-angiogenesis or other anti-cancer mechanisms. The compounds specified are 6H-dibenzo[b,d]pyran-6-one derivatives and have been shown to be antiproliferative against human endothelial cells.
Patent CA-2438955-A1 (CA)
Inventor: TORII TORU
IPC: B01L3/00
Filed: 2002-02-21
Abstract: A liquid particulate-handling method and device, in which the evaporation of the droplets is prevented and therefore the handling of the droplets is appropriately performed, are provided.  In the handling of liquid particulates, a chemically inert solution (4), having microdroplets (5) therein, is set on a substrate (1) having handling electrodes (2) arranged in a two-dimensional manner; and the voltages of the handling electrodes (2) are controlled, thereby handling the microdroplets (5).
Patent CA-2439505-A1 (CA)
Title: Pipe clamp
Inventor: KROHMER STEVEN D
IPC: B25B1/10
Filed: 2003-09-04
Abstract: A pipe clamp for clamping objects has wide, stable feet that prevent the clamp from tipping over. The feet are of such a height that the clamp handle can be rotated by the user without interference from the bench on which the pipe clamp rests. The clamping faces have holes drilled through them to allow jigs or cauls to be attached to the clamping faces to clamp unusually shaped objects. The clamp also has a hook on the foot for convenient hanging of the clamp for storage.
Patent CA-2439917-A1 (CA)
Title: Compositions having improved bioavailability of eletriptan
Inventor: HUMPHREY MICHAEL JOHN
IPC: A61K31/40
Filed: 2002-02-20
Abstract: The bioavailabilty of eletriptan can be increased by co-administering eletriptan with a p-glycoprotein (p-gp) inhibitor. The eletriptan and p-gp inhibitor can be administered together in a composition or as separate components. If administered separately, they can be embodied as a kit.</SDOA B>
Patent CA-2440835-A1 (CA)
Title: Application synchronisation
Inventor: WISEMAN RICHARD MICHAEL
IPC: H04L29/08
Filed: 2002-04-02
Abstract: The invention relates to multi-modal interfaces and the synchronisation of two or more application programs which have user interfaces which make up the multi-modal interface. The invention employs a synchronisation server process with blackboard style data store for posting the changes made to any one particular application program to the other application programs. Data updates pass via the synchronisation server. A map file is provided for translating data provided by one application program into the formats suited to other application programs, and vice versa. In this way, application programs are not limited by a common dialogue but are autonomous, thus providing a cohesive and highly flexible user interface.
Patent CA-2440908-A1 (CA)
Inventor: ERMISCH JOCHEN
IPC: G05F1/147
Filed: 2002-03-26
Abstract: L'invention concerne un dispositif permettant d'influer automatiquement sur un réseau d'alimentation électrique. Un transformateur de tension utilisé comme transducteur de mesure détecte la valeur réelle de chaque tension à régler et transmet cette valeur au moyen d'une ligne de mesure à une commande à moteur, laquelle comporte des moyens destinés à comparer cette valeur réelle avec une valeur théorique prédéfinie, et à produire une commande de positionnement en fonction du résultat de cette comparaison. L'invention concerne en outre une commande à moteur correspondante comprenant un module de commande supplémentaire qui, en cas de besoin, actionne directement un moteur électrique en fonction du sens de rotation. Ledit moteur électrique actionne, quant à lui, un commutateur à gradins du transformateur à gradins et procède ainsi au réglage de tension permettant d'influer sur le réseau d'alimentation électrique.
Patent CA-2441364-A1 (CA)
Title: Pre-processing train operational data using variable exception reporting
Inventor: HAWTHORNE MICHAEL J
IPC: G06Q10/06
Filed: 2003-09-17
Abstract: A method of analyzing train operational data recorded during each run of a train and transferred to a processing station. Operational and informational parameters are derived from the recorded operational data for each run. The operational and identification parameters and the corresponding operational data are stored as a standard database record for each run. The operational parameters are compared to selected exception values and the variance of the comparison are stored with the standard operational database record for each run. A search is then performed of the stored standard database records based on one or more of operational parameter, identification parameter, operational data and variance.
Patent CA-2441821-A1 (CA)
Inventor: ASHKENAZI NISSAN
IPC: C07C381/00
Filed: 2002-04-15
Abstract: The present invention provides a process for preparing a metal carbene compl ex of formula (I): wherein M is a transition metal atom selected from the group consisting of ruthenium, rhodium, iron , cobalt, osmium and iridium; L denot es neutral donor ligands ligated to said metal, such groups being the same or different; X is an anionic ligand; R1 and R2 are each independently selected from the group consisting of hydrogen, substituted or unsubstituted C1-C20 alkyl, substituted or unsubstituted C2-C20 alkenyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted vinyl, a is 2 or 3 and b is 1 or 2, such proces s comprising reacting a sulfur ylide of the formula Ar2S=CR1R2 or its precurso r with an appropriate metal complex comprising a transition metal atom selecte d from the group consisting of ruthenium, rhodium, iron, cobalt, osmium and iridium, said metal complex being also in dimeric form, at a temperature between +80 ~C and -80 ~C, in an inert solvent and under inert atmosphere.</ SDOAB>
Patent CA-2442005-A1 (CA)
Inventor: KREVALIS MARTIN A
IPC: C10M105/24
Filed: 2003-09-22
Abstract: This invention generally relates to a high temperature stable polyol ester lubricant composition containing short chain carboxylic esters and a process for making the same. The polyol ester lubricant compositions are preferably formed from pentaerythritol and a mixture of C2 to C10 carboxylic acids in which (1) from 95 to 80 mole%, based on total acids, are C5 to C10 carboxylic acid, and (2) from 5 to mole%, based on total acids, are at least one C2 to C4 carboxylic acid The polyol ester lubricant compositions of the present invention, specifically those using at least one C2 to C4 carboxylic acid, are useful as base stock for high temperature application such as Aviation Turbine Oils and exhibit enhanced anti-deposition and oxidation stability compared with the base polyol ester compositions while maintaining a good viscosity index.
Patent CA-2442598-A1 (CA)
Title: Vessel sealer and divider with non-conductive stop members
Inventor: DYCUS SEAN T
IPC: A61B17/32
Filed: 2001-04-06
Abstract: An endoscopic bipolar forceps for sealing and dividing tissue includes an elongated shaft having opposing jaw members at a distal end thereof. The jaw members are movable relative to one another from a first position wherein th e jaw members are disposed in spaced relation relative to one another to a second position wherein the jaw members cooperate to grasp tissue therebetween. The jaws members are connected to a source of electrical energ y such that the jaw members are capable of conducting energy through tissue he ld therebetween to affect a tissue seal. At least one non-conductive and spaced - apart stop member is disposed on an inner-facing surface of the jaw members to regulate the gap distance between the jaw members when tissue is held therebetween. The forceps also includes a longitudinally reciprocating knife which severs the tissue after sealing at a location which is proximate the sealing site.
Patent CA-2442951-A1 (CA)
Inventor: YAN CHUNHUA
IPC: C12N9/02
Filed: 2002-04-01
Abstract: La présente invention concerne des séquences d'acides aminés de peptides codés par des gènes compris dans le génome humain, soit des peptides enzymatiques de métabolisation de médicaments. Plus particulièrement, la présente invention concerne des molécules d'acides nucléiques et des molécules peptidiques isolées, des méthodes d'identification d'orthologues et de paralogues de ces peptides enzymatiques de métabolisation de médicaments, ainsi que des méthodes d'identification de modulateurs desdits peptides enzymatiques de métabolisation de médicaments.
Patent CA-2446977-A1 (CA)
Inventor: MORNEWECK DANIEL L
IPC: B23Q16/00
Filed: 2002-05-14
Abstract: L'invention concerne un procédé et un appareil permettant de détecter une discontinuité, telle qu'un trou, dans une pièce à usiner. L'appareil comprend une sonde comportant un manche fixé à une poignée et destinée à détecter une discontinuité par rapport à un système de coordonnées. Ladite sonde comporte une unité terminale fixée à l'extrémité du manche opposée à celle où est fixée la poignée. L'unité terminale est configurée de manière à toucher une surface associée à la discontinuité, et à se déplacer par rapport au système de coordonnées pour être alignée à un axe associé à ladite discontinuité. Au moins un capteur de position se situe intégralement dans le manche et est configuré pour détecter la position de l'unité terminale par rapport audit système de coordonnées. Le manche comporte une pluralité de cavités et le capteur se trouve dans au moins une de ces cavités.
Patent CA-2447035-A1 (CA)
Title: A method of operating a mass spectrometer to suppress unwanted ions
Inventor: BANDURA DMITRY R
IPC: H01J49/00
Filed: 2002-05-09
Abstract: In a mass spectrometry system, a method of operating a processing section, for example a collision cell, is provided. The method is based on the realization that some interfering ions after collision will have significantly lower kinetic energy than desired analyte ions. These interfering ions can be ions originating from the source, or product ions formed by reaction with gas particles, or ions produced by other processes within the cell. Significantly, these interfering ions can have lower kinetic energies, as compared to desired analyte ions, but this energy differential disappears, or is much reduced, at the exit of the collision cell, rendering post-cell energy discrimination less effective. The invention provides a field within the cell to discriminate against the interfering ions based on their lower kinetic energy.
Patent CA-2448202-A1 (CA)
Title: Catheter having a low drag septum
Inventor: JIN CHENG KIAT
IPC: A61M25/06
Filed: 2002-05-24
Abstract: The catheter and introducer needle assembly of this invention includes a catheter adapter at its proximal end having a hollow disposed therein. The septum preferably is hollow to minimize drag as the introducer needle is removed therefrom. If desired a gel or lubricious material may be disposed i n the cavity.
Patent CA-2450025-A1 (CA)
Title: A winglet
Inventor: BRAY ROBERT MICHAEL
IPC: B64C5/08
Filed: 2002-06-12
Abstract: A winglet (12) for an aircraft wing is provided. The winglet (12) has an airflow control arrangement, for example in the form of a trailing edge flap (20) by means of which lift generated by the winglet can be varied. The control arrangement desirably forms part of a manoeuvre load alleviation system (22) for the aircraft.
Patent CA-2451137-A1 (CA)
Inventor: THOMPSON JENNIFER LEIGH
IPC: C08L67/00
Filed: 2002-08-01
Abstract: La présente invention concerne un composite en feuille à surface solide extrudé et bien rebouché qui possède une thermorésistance, une résistance au solvant et une résistance à l'abrasion améliorées obtenues par une combinaison de polymère vitreux et de polymère semi-cristallin.
Patent CA-2454307-A1 (CA)
Inventor: NAKASHIMA TOSHIHIRO
IPC: C12N15/13
Filed: 2002-07-18
Abstract: L'invention concerne un anticorps ou un fragment d'anticorps efficace pour traiter des affections allergiques dans lesquelles IgE est partie prenante. L'utilisation du procédé d'anticorps phage, d'un anticorps humain et d'un fragment d'anticorps contre un récepteur (Fc.epsilon.RI) possédant une grande affinité avec le fragment Fc de IgE sont obtenus. En raison de l'activité d'inhibition de l'activité de liaison de IgE au récepteur IgE, ce récepteur antiIgE humain et son fragment anticorps sont supposés servir dans des remèdes contre les affections allergiques causées par la liaison de IgE au récepteur IgE.
Patent CA-2454389-A1 (CA)
Title: Solid composition containing bacillus-type non-pathogenic bacterial spores
Inventor: PRATO TIZIANO
IPC: A61K47/04
Filed: 2002-07-26
Abstract: The invention relates to a composition of Bacillus-type non-pathogenic bacterial spores which are adsorbed on a matrix formed by at least one water-insoluble adsorbent compound and a cellulose derivative. The inventive composition can be obtained using the air-fluidised bed technique and said composition is suitable for use in the pharmaceutical, veterinary and nutritional fields.
Patent CA-2461817-A1 (CA)
Title: Truck for shredding and mixing products for zootechnical use
Inventor: FACCIA TIZIANO
IPC: A01K5/00
Filed: 2002-09-25
Abstract: A truck for shredding and mixing products for zootechnical use, of the type that comprises, on a chassis (11) with wheels (12) that is self-propelled or towed, a container (13) that is substantially shaped like an inverted frustrum, is open in an upper region and contains shredding and mixing means (14) which comprise at least two adjacent rotating main screw feeders (15, 1 6) each having an external profile (17) that lies on a substantially conical imaginary surface and at which shredding cutters are mounted. Contrast cutte rs (20) substantially shaped like circular sectors are hinged to the internal wall of the container (13) by means of their respective vertices in a vertic al arrangement in substantially radial positions and can be inserted and remove d through appropriately provided slots. Auxiliary screw feeders (18, 19), suitable to avoid the formation of stagnation regions, are arranged between the main screw feeders (15, 16), in the regions adjacent to the walls of the container (13).
Patent CA-2462107-A1 (CA)
Inventor: FEHL ROBERT J
IPC: B67D7/30
Filed: 2002-09-03
Abstract: A system for delivering a preset volume of fluid, such as oil, includes a master control station (1) and one or more metering devices (8) communicatively linked through a wireless communications network. The master control station (1) provides command signals to enable dispensing of a fluid from the metering device (8) and provides a present amount of fluid to be dispensed. The metering device (8) is manually activated by a manually-operated lever (14), and is thereafter latched in an open position to dispense lubricant. The amount of lubricant dispensed is metered until the predetermined amount of lubricant is dispensed. After the preset amount is dispensed, the metering device (8) is latched in a closed position, preventing further dispensing until the metering device (8) is again enabled by the master control station (1).
Patent CA-2462806-A1 (CA)
Inventor: NETTEKOVEN MATTHIAS HEINRICH
IPC: A61P43/00
Filed: 2002-10-04
Abstract: La présente invention se rapporte à des composés de la formule (1) dans laquelle R?1¿ est -NR'R", où R' et R" sont indépendamment l'un de l'autre alkyle inférieur, -(CH¿2?)¿n?-C(O)NR¿a?R¿b?, -(CH¿2?)¿n?-hétéroaryle, -(CH¿2?)¿n?-aryle, -(CH¿2?)¿n?-CN, -(CH¿2?)¿n?-O-alkyle inférieur ou -(CH¿2?)¿n?-cycloalkyle, ou R'et R" forment ensemble avec l'atome N un cycle non aromatique à cinq ou six chaînons, qui peut contenir un hétéroatome supplémentaire O ou S, et dont les noyaux peuvent être non substitués ou substitués par un ou deux substituants, choisis dans le groupe composé de l'alkyle inférieur, de -C(O)NR¿a?R¿b? ou -(CH¿2?)¿n?-O-alkyle inférieur, et R¿a?R¿b? sont indépendamment l'un de l'autre hydrogène ou alkyle inférieur ; R?2¿ est aryle ou hétéroaryle, non substitué ou substitué par un alkyle inférieur ou un halogène; n est 0, 1, 2 ou 3; et à leurs sels pharmaceutiquement acceptables. Les composés de l'invention peuvent être utilisés dans le traitement de maladies, associés au récepteur A2 de l'adénosine.
Patent CA-2465389-A1 (CA)
Title: Operating device and method for operating gas discharge lamps
Inventor: BREUER CHRISTIAN
IPC: H05B41/38
Filed: 2004-04-28
Abstract: The ignition of a gas discharge lamp is followed by a warm-up phase. During the warm-up phase, as much power must be converted in the lamp as enables the lamp to make a transition to an operating phase. In this process, currents flow at a damaging level into the electrodes of the lamp in the case of operating devices of the prior art. The invention presented avoids these high currents by means of an operating device having the following features:   .cndot. a regulation device which is suitable for regulating the power of connected gas discharge lamps to a desired power, .cndot. a setting device that is suitable for limiting a lamp current of connected gas discharge lamps to a limit value, .cndot. a detection device designed to output a signal to the control device if a limit value setting is too low, in order to put a connected gas discharge lamp into a state in which the lamp assumes the desired power, and .cndot. a control device that prescribes the limit value for the setting device and increases the limit value if the detection device sends a signal to the control device.
Patent CA-2466098-A1 (CA)
Title: Seeding apparatus
Inventor: DIKA MICHAEL
IPC: A01C7/00
Filed: 2004-05-03
Abstract: A seeding apparatus plants seed in the ground with a minimum soil disturbance. A base plate is provided which is supported for sliding movement along the ground and which includes a plurality of seed apertures formed therein. A metering system meters seed from a seed hopper to the seed apertures. Reciprocating push-rods subsequently push the seed through the seed aperture to a prescribed depth below a surface of the ground. As the seed remains in contact with moist soil below the surface of the ground, rapid germination results without concern for seed runoff when seeding sloped surfaces.
Patent CA-2468472-A1 (CA)
Inventor: KURIGER REX J
IPC: G01N21/77
Filed: 2004-05-26
Abstract: According to one embodiment of the present invention, an optical-based test sensor for use in the determination of an analyte in a liquid sample is disclosed.  The test sensor includes a base, a polymer carrier, and a test membrane. The base has a capillary channel formed in a surface of the base that is adapted to move a liquid sample from an inlet to a reaction area formed in the base. The polymer carrier has a lower surface adhered to the surface of the base and is disposed over at least a portion of the capillary channel.  The test membrane, which contains a reagent, is adhered to the lower surface of the polymer carrier and extends from the polymer carrier into the reaction area.
Patent CA-2469014-A1 (CA)
Title: Film for composite security disks with self-adhesiveness
Inventor: HOSS MANFRED
IPC: B32B17/10
Filed: 2002-12-17
Abstract: Films containing a plasticiser based on partially acetalised polyvinyl alcohols, especially PVB, adapted in such a manner that the intermediate lay er in the composite security glass exhibit, aswell as excellent adhesiveness wi th respect to glass, non-desirable self-adhesiveness (blocking-tendency). A pentaerythrite ester of between 0.0001 0.1 wt % is therefore used as an additive to reduce said adhesiveness. Said additive does not alter the adhesiveness of the film with respect to glass. The invention is used in the production of films for producing composite security glass. The need for cooling the films in order for them to stacked or rolled up is greatly reduc ed.
Patent CA-2470013-A1 (CA)
Title: Transport system for instant messaging
Inventor: HOLMES JOHN
IPC: H04L69/40
Filed: 2004-06-01
Abstract: ® An exemplary method involves creating a master session over a first connection through a server; and creating a virtual channel over the connection, the virtual channel operable to communicate a feature session. The method may involve establishing a direct connection that bypasses the server, and switching communication of the feature session to the direct connection. A system for network communication includes a plurality of transport bridges, each transport bridge corresponding to an active network device configuration, and a switching module operable to choose one of the transport bridges to form a connection between two computing devices based on the active network device configuration.
Patent CA-2471965-A1 (CA)
Title: Grab bar for shower and the like
Inventor: MOORE SEAN
IPC: A47K3/00
Filed: 2004-06-22
Abstract: A safety grab bar, such as may be used in a shower or a tub enclosure, comprises an inner liner, preferably formed of an extruded metal, and an outer overlying layer, preferably formed of a polymeric material such as plastic. The inner and outer liner mate together with a tongue and groove arrangement to prevent relative rotation between them.   The inner liner and the outer overlying layer define the grab bar portion, and terminate at each end in a female receptacle, adapted to receive a male portion of a mounting bracket.   The mounting bracket smoothly curves to complete a 90E turn, in order mount into a wall of the shower or bath enclosure. The male and female mating portions are flush at their outer dimensions to provide a smooth, unbroken profile. The male and female portions also include tongue and groove mating surface to prevent rotation of the grab bar within the mounting bracket.
Patent CA-2472617-A1 (CA)
Title: Substituted amino carboxamides for the treatment of alzheimer's disease
Inventor: WARPEHOSKI MARTHA A
IPC: A61P25/16
Filed: 2003-01-06
Abstract: The present invention relates to compounds of formula (I) useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the betasecretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharamaceutical compositions and methods of treatment to reduce A beta peptide formation.
Patent CA-2473996-A1 (CA)
Title: Methods and compositions for the promotion of hair growth utilizing actin binding peptides
Inventor: PHILP DEBORAH
IPC: A61K38/08
Filed: 2003-01-22
Abstract: Disclosed herein are methods and compositions suitable for the promotion of hair growth on humans and other animals. Disclosed embodiments include compositions comprising actin-binding peptides. In some embodiments, the actin- binding peptides comprise fragments of thymosin .beta.4. In other embodiments, the disclosure provides compositions comprising fragments of thymosin .beta.4 and/or other actin-binding peptides that are suitable for the treatment of alopecia and other conditions associated with hair loss. In still further embodiments, the disclosure provides compositions comprising the sequence of approximately six or seven amino acids of the thymosin .beta. 4 sequence that bind actin.