baber/WOPTO huggingface dataset:
Patent AU-2021328649-A1 (AU)
Title: Localized delivery of diagnostic or therapeutic agents using focused ultrasound
Inventor: YANIK MEHMET
IPC: A61K9/00
Filed: 2021-08-16
Abstract: In a method for enhancing localized delivery of a diagnostic or therapeutic agent using focused ultrasound (FUS), ultrasound-controllable drug carriers are administered into a blood vessel. Each drug carrier comprises an ultrasound-sensitive microbubble loaded with the diagnostic or therapeutic agent. The drug carriers are aggregated inside the vessel both along a radial direction and a longitudinal direction by application of an aggregation FUS sequence. Subsequently the diagnostic or therapeutic agent is released from the drug carriers by application of an uncaging FUS sequence. The aggregation and uncaging sequences are applied using FUS below a threshold power level such that harmful cavitation is avoided, as evidenced by the absence of broadband emissions and preferably non-integer harmonics from an emission spectrum of the drug carriers. Thereby damage to the vasculature by the FUS sequence is avoided. The method can in particular be employed to deliver drugs to the brain without opening the blood-brain barrier.
Patent AU-2021342558-A1 (AU)
Title: Combination therapy using bax activator agent
Inventor: GAVATHIOTIS EVRIPIDIS
IPC: A61P35/00
Filed: 2021-09-17
Abstract: A pharmaceutical combination comprising a B-cell lymphoma 2 associated X protein (BAX) activating compound an anti-apoptotic protein inhibiting compound is provided. The disclosure also provides a method of treating cancer in a subject by administering a B-cell lymphoma 2 associated X protein (BAX) activating compound in combination with an anti-apoptotic protein inhibiting compound, such as a BCL-XL, BCL-2, BFL-1. BCL-w, or MCL-1 inhibiting compound.
Patent AU-2021393968-A1 (AU)
Title: Process for the preparation of (9s)-n-[3-(6-methylpyrimidin-4-yl)-3-azabicyclo[3.2.1]octan-8-yl]-9-(2,3,4-trifluorophenyl)-6,7,8,9-tetrahydro-5h-[1,2,4]triazolo[1,5-a]azepin-2-amine and its solid form
Inventor: CHEN WEICHUN
IPC: C07D487/04
Filed: 2021-12-09
Abstract: The present invention relates to a process for the preparation of a compound (I), and its solid form, which is a modulator of γ-secretase and may be useful for prophylaxis and treatment of a disease associated with the deposition of β-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.
Patent AU-2021396584-A1 (AU)
Title: Treatment regimen for onchyomycosis using allylamine antifungal compositions
Inventor: WÄRNHEIM TORBJÖRN
IPC: A61K31/137
Filed: 2021-12-07
Abstract: There is provided a method of treating onychomycosis of the nail, comprising topical application of a pharmaceutical composition comprising an antifungal allylamine compound and a non-aqueous solvent system, which method comprises a loading phase, during which the pharmaceutical composition is administered at least three times a week, followed by a maintenance phase, during which the pharmaceutical composition is administered no more than two times per week. There are further provided pharmaceutical compositions suitable for topical application to the nail comprising an antifungal allylamine compound, an organic acid component and a diol component, as defined herein, and their use in methods of treating onychomycosis.
Patent WO-2023000038-A1 (WO)
Inventor: GEARING ANDREW
IPC: C07K5/11
Filed: 2022-07-22
Abstract: The present invention provides various peptide compositions capable of binding Lanthionine synthetase C-like protein (LanCL) that have analgesic, anti-inflammatory and anti-microbial properties.The compositions comprise a peptide formula (I): X1-X2-X3- X4-X5-X6, wherein X represents specific groups of amino acids, and the peptide is 3-20 amino acids in length, it does not comprise sequences CRSRPVESSC, CRSVEGSCG, or CRIIHNNNC and is not a linear peptide comprising the sequence EQLERALNSS.
Patent AU-2022200671-A1 (AU)
Title: Slow retraction mechanism, locking-type slow retraction device and winding device
Inventor: GE GUIZHONG
IPC: B65H75/48
Filed: 2022-02-02
Abstract: A slow retrieve mechanism, a locking slow retrieve device and a winding device.  
The slow retrieve mechanism fits with a winder including a main shaft and a main 
body rotatably sleeved on the main shaft to rotate around it to wind or unwind a 
flexible material and includes a blocking part, a decelerating part rotatably arranged 
on the main body and located in the blocking part, and an elastic part arranged on the 
main body and connected with the decelerating part. When the main body rotates 
around the main shaft in a first direction to wind, the decelerating part rotates relative 
to the main body along a second direction opposing the first direction to approach the 
blocking part to contact and rub it to reduce a rotation speed of the main body. The 
elastic part applies an elastic force to hinder the decelerating part from rotating along 
the second direction.
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Fig. 1
Patent AU-2022201269-A1 (AU)
Title: Method of treating diseases
Inventor: MAMLUK RONI
IPC: A61K9/48
Filed: 2022-02-24
Abstract: Methods of treating acromegaly in a subject are described herein. Exemplary methods 
include orally administering to the subject at least once daily at least one dosage form 
comprising octreotide, wherein the octreotide in each dosage form is 20 mg, and wherein the 
administering occurs at least 1 hour before a meal or at least 2 hours after a meal.
Patent AU-2022201435-A1 (AU)
Title: Connecting component
Inventor: NEUWIRTH DETLEF
IPC: E04G7/22
Filed: 2022-03-02
Abstract: The invention relates to a connecting component for connecting different scaffolding 
systems, comprising at least a first connection region, which is provided for 
5 connection to a first scaffolding system and which has a shaft that extends along a 
longitudinal axis, and an attachment region which is provided for connection to a 
second scaffolding system, wherein the first connection region and the attachment 
region are arranged adjacent to one another in the direction of the longitudinal axis 
and the first connection region has a receptacle in its interior in the shaft, at least on 
10 its side pointing away from the attachment region, which extends in the direction of 
the longitudinal axis. The attachment region has an abutment adjacent to the first 
connection region extending in a direction essentially perpendicular to the 
longitudinal axis, and the abutment has the longest dimension of the attachment 
region in the direction essentially perpendicular to the longitudinal axis. The invention 
15 further relates to a scaffolding section for connecting different scaffolding systems 
with a connecting component.  
[Fig. 2] 
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Patent AU-2022201830-A1 (AU)
Title: Reduced pressure apparatus and methods
Inventor: ASKEM BEN ALAN
IPC: A61M1/00
Filed: 2022-03-16
Abstract: An apparatus for treating a wound with topical negative 
pressure therapy comprising: a wound dressing comprising a 
pump and a power source including one or more batteries 
wherein the dressing is configured to support the pump and 
power source such that the pump and power source is on-board 
the dressing and further comprising a control board and/or 
user interface positioned on the dressing; and a wound contact 
surface covered with an adhesive to permit the 
repositionability of the wound dressing over a wound site.  
FIG. 1A 
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Patent AU-2022203420-A1 (AU)
Title: Augmented reality interface for assisting a user to operate an ultrasound device
Inventor: Rothberg Alex
IPC: G09B23/28
Filed: 2022-05-20
Abstract: Aspects of the technology described herein relate to techniques for guiding an 
operator to use an ultrasound device. Thereby, operators with little or no experience 
operating ultrasound devices may capture medically relevant ultrasound images and/or 
interpret the contents of the obtained ultrasound images. For example, some of the 
techniques disclosed herein may be used to identify a particular anatomical view of a subject 
to image with an ultrasound device, guide an operator of the ultrasound device to capture an 
ultrasound image of the subject that contains the particular anatomical view, and/or analyze 
the captured ultrasound image to identify medical information about the subject.
Patent AU-2022204432-A1 (AU)
Title: Benzimidazole derivatives for treatment and/or prevention of diseases and disorders mediated by NLRP3
Inventor: TSENG YUFENG JANE
IPC: A61K31/4184
Filed: 2022-06-23
Abstract: BENZIMIDAZOLE DERIVATIVES FOR TREATMENT AND/OR PREVENTION OF 
DISEASES AND DISORDERS MEDIATED BY NLRP3 
Abstract of the Disclosure 
5 The present disclosure relates to a method for prevention and/or treatment of a disease or disorder 
mediated by NLRP3 in a subject, comprising administering an effective amount of a compound of 
Formula (I) or a pharmaceutically acceptable salt, solvate or prodrug as disclosed herein 
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Patent AU-2022205174-A1 (AU)
Title: Anti-C1S antibodies and methods of use thereof
Inventor: PANICKER SANDIP
IPC: A61K39/395
Filed: 2022-07-12
Abstract: The present disclosure provides antibodies that specifically bind complement pathway 
component Cls. The present disclosure provides nucleic acids comprising nucleotide sequences 
encoding the anti-Cs antibodies; and host cells comprising the nucleic acids. The present 
disclosure provides compositions comprising the anti-Cis antibodies. The present disclosure 
provides methods of use of the anti-CIs antibodies.  
18877667_1 (GHMATTERs) P45114AU01
Patent AU-2022205209-A1 (AU)
Title: Novel peptides and combination of peptides for use in immunotherapy against esophageal cancer and other cancers
Inventor: MAHR ANDREA
IPC: A61K39/00
Filed: 2022-07-13
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in 
immunotherapeutic methods. In particular, the present invention relates to the 
immunotherapy of cancer. The present invention furthermore relates to tumor
associated T-cell peptide epitopes, alone or in combination with other tumor
associated peptides that can for example serve as active pharmaceutical ingredients 
of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate 
T cells ex vivo and transfer into patients. Peptides bound to molecules of the major 
histocompatibility complex (MHC), or peptides as such, can also be targets of 
antibodies, soluble T-cell receptors, and other binding molecules.
Patent AU-2022220595-A1 (AU)
Title: Apparatus and methods for transferring a tissue section
Inventor: SCHLEIFER KYLE
IPC: G01N35/00
Filed: 2022-01-31
Abstract: The invention relates to apparatus and methods for automated tissue sectioning, including slicing and transferring a tissue section to a slide. The invention also relates to automated systems and methods for transferring a tissue section onto a slide using an adhesive strip.
Patent AU-2022221480-A1 (AU)
Title: Agricultural machine speed control based on work quality metrics
Inventor: HANSEN MATTHEW D
IPC: G05D1/02
Filed: 2022-08-25
Abstract: AGRICULTURAL MACHINE SPEED CONTROL BASED ON WORK 
QUALITY METRICS 
ABSTRACT 
A method of controlling a mobile agricultural machine that includes detecting a target value 
5 setting input identifying a target metric value for a quality metric representing a performance 
characteristic of the mobile agricultural machine and having an inverse relationship to machine 
speed, receiving machine data indicative of operating parameters on the mobile agricultural 
machine, generating, based on the machine data, a current metric value for the quality metric, 
determining a target machine speed based on the current metric value relative to the target metric 
.0 value, and outputting a control instruction that controls the mobile agricultural machine based on 
the target machine speed.
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Patent AU-2022228016-A1 (AU)
Title: Insecticidal composition comprising of diamide, moulting hormone agonist and pyrethroid
Inventor: MUNDHRA PARIKSHIT
IPC: A01N43/40
Filed: 2022-02-22
Abstract: The present provides a synergistic insecticidal composition comprising Chlorantraniliprole, Methoxyfenozide and at least one insecticidal compound selected from Deltamethrin or Lambda-Cyhalothrin, process of preparation of the composition and uses thereof.
Patent AU-2022228734-A1 (AU)
Title: High strength wrapping material containing extracted tobacco
Inventor: ALVAREZ HUGUES
IPC: A24D1/02
Filed: 2022-03-01
Abstract: A wrapping material for an aerosol producing product is disclosed that contains extracted tobacco material combined with strength building fibers. The strength building fibers are refined and optionally bleached bast fibers. In one aspect, the bast fibers can be hemp fibers. The wrapping material can contain the extracted tobacco material in amounts greater than 40% by weight.
Patent AU-2022240879-A1 (AU)
Title: Cleaning head for a wet vacuum cleaner
Inventor: DE WIT BASTIAAN JOHANNES
IPC: A47L11/40
Filed: 2022-03-09
Abstract: A cleaning head for a wet vacuum cleaner has first and second rotary brushes, each extending across a width of a housing. The housing comprises a first projection extending inwardly into a space between the brushes and having a first guide channel creating an air cavity over the floor, and a second projection extending inwardly the said space. The second projection has a second guide channel creating another cavity over the floor. These cavities promote lateral air flow into the space between the brushes and thereby reduce pooling of water.
Patent AU-2022254384-A1 (AU)
Title: Packaging container-filler member, packaging container, contents-filled packaging container, and method of manufacturing contents-filled packaging container
Inventor: NAGATA KENJI
IPC: B65D33/02
Filed: 2022-04-08
Abstract: This filler member (10, 10b) for a packaging container comprises: an obverse-side sheet (11) and a reverse-side sheet (12) that are disposed so as to face each other; a first linking sheet (13A) that links the outer edges of first-direction (X) first sides (X1) of the obverse-side and reverse-side sheets, the first direction following the obverse-side sheet; a second linking sheet (13B) that links the outer edges of first-direction second sides (X2) of the obverse-side and reverse-side sheets; and a third linking sheet (14) that links the outer edges of second-direction (Y) first sides (Y1) of the obverse-side and reverse-side sheets, the second direction following the obverse-side sheet and intersecting the first direction. The obverse-side sheet, the reverse-side sheet, the first linking sheet, and the second linking sheet constitute a tubular body that has a rectangular cross-section when formed into a three-dimensional shape. Each of the first linking sheet, the second linking sheet, and the third linking sheet is folded in a facing direction Z in which the obverse-side and reverse-side sheets face each other.
Patent AU-2022259360-A1 (AU)
Title: A bacteriophage preparation in the form of gel to prevent or treat bacterial infections in dairy cattle, its manufacturing method and bacteriophage strains
Inventor: DASTYCH JAROSŁAW
IPC: A61K31/731
Filed: 2022-04-11
Abstract: A bacteriophage preparation in the form of gel to prevent or treat bacterial infections in dairy cattle, including but not limited to infections caused by E.coli and/or S. aureus, intended for intramammary administration during lactation or dry period, in particular, to treat or prevent mastitis in dairy cattle, its manufacturing method and bacteriophage strains especially useful for such preparation manufacturing, characterised in detail in the enclosed patent claims, was revealed.
Patent AU-2022259682-A1 (AU)
Title: In-floor swimming pool cleaning head
Inventor: GOETTL STEVEN JAMES
IPC: E04H4/12
Filed: 2022-04-15
Abstract: An incrementally rotating in-floor swimming pool cleaning head with a retainer body, a nozzle stem, a ratcheting pin, a removable stationary cam unit, a reversible bayonet, and a removable top ring. The cam unit is stationary in relation to itself and without moving parts. When the cam unit engages the ratcheting pin in a first orientation, the nozzle stem reciprocally operates to ratchet in a clockwise direction, and when the cam unit engages the ratcheting pin in a second orientation, the nozzle stem operates in a counter-clockwise direction. The reversible bayonet includes a plurality of lugs configured to couple to a bayonet connector of the nozzle stem in each of a first orientation configured for a spring powered retracting nozzle, and a second orientation configured for a weighted retraction nozzle.
Patent AU-2022269312-A1 (AU)
Title: Cd20 and cd22 targeting antigen-binding molecules for use in proliferative diseases
Inventor: PANZER MARC
IPC: C07K16/28
Filed: 2022-05-06
Abstract: The present invention provides CD20 and CD22 targeting antigen-binding molecules characterized by comprising a first and a second domain, binding to CD20 and CD22, respectively, a third domain binding to an extracellular epitope of the human and the
Patent AU-2022281293-A1 (AU)
Title: Imaging lens system and scan engine chassis
Inventor: WITTENBERG CARL D
IPC: G06K7/10
Filed: 2022-05-19
Abstract: A scan engine for capturing at least one image of an object appearing in an imaging field of view (FOV) is provided that includes an imaging system and a chassis. The imaging system includes a lens holder and at least one lens disposed within the lens holder. The lens holder includes a lens holder mounting portion. The chassis includes a chassis mounting portion adapted to couple with the lens holder mounting portion.
Patent AU-2022316889-A1 (AU)
Title: Dnvsig3 and dnvsig8 receptors and methods of using the same
Inventor: BEDOYA FELIPE
IPC: C07K14/705
Filed: 2022-07-25
Abstract: Described are dominant-negative receptor mutants of V-Set and Immunoglobulin domain containing 3 (VSIG3) receptors and V-Set and Immunoglobulin domain containing 8 (VSIG8) receptors and methods of making the same for use in applications drawn to modulating the downstream signal transduction effects of VSIG3 and VSIG8 and their corresponding ligands. The invention is drawn to use of the use of the dnVSIG3 and/or dnVSIG8 receptor mutants to mitigate immunosuppressive effects associated with functional forms of VSIG3 and/or VSIG8 in the presence of their cognate ligands.
Patent AU-2023200995-A1 (AU)
Title: RNA molecules
Inventor: SMITH NEIL ANDREW
IPC: C12N15/113
Filed: 2023-02-21
Abstract: The present invention relates to new double stranded RNA (dsRNA) structures 
and their use in gene silencing. In one embodiment the dsRNA comprises a double 
hairpin (dumbbell) structure. In another embodiment a proportion of the sense and 
5 antisense strands of the dsRNA molecule contain ribonucleotides that are either 
basepaired in a non-canonical basepair or are not basepaired.
Patent AU-2023203550-A1 (AU)
Title: Composite vitamin composition promoting gastrointestinal system motility
Inventor: ZHOU MINGDONG
IPC: A61K31/714
Filed: 2023-06-07
Abstract: Disclosed are composite compositions of B vitamins and C vitamins and the use of 
same in the preparation of a drug or health food for treating and/or preventing 
gastrointestinal conditions diseases related to deficiency of the gastrointestinal system 
motility. The composition comprises a vitamin B composition or an analogue or a 
derivative thereof and a vitamin C or an analogue or a derivative thereof.  
35
Patent AU-2023203591-A1 (AU)
Title: Display method and apparatus
Inventor: ZHU DENGKUI
IPC: G06F3/14
Filed: 2023-06-08
Abstract: DISPLAY METHOD AND APPARATUS 
ABSTRACT 
Embodiments of this application provide a display method and an apparatus, and 
relate to the field of communications technologies, to resolve a technical problem of 
low efficiency when a terminal switches an application between a plurality of screens 
5 to display the application, thereby improving user experience in using the terminal as 
a PC. The method includes: after a first terminal connects to a second terminal, 
obtaining, by the first terminal, a first gesture made by a user on a target shortcut in a 
first display interface, where the first display interface is an interface presented on the 
first terminal, and target content corresponding to the target shortcut is not running in 
10 a foreground of the first terminal; and sending, by the first terminal, first display data 
to the second terminal based on the first gesture, so that the second terminal displays 
the first display data in a second display interface, where the first display data is data 
correlated with the target content, and the second display interface is an interface 
presented on the second terminal.
Patent WO-2013159160-A1 (WO)
Title: Procédé et dispositif de communication avec un distributeur automatique
Inventor: TSENEV STEFAN GEORGIEV
IPC: G07F11/00
Filed: 2013-04-22
Abstract: Le procédé d'après la présente invention comprend une détection de données. A cette fin, le procédé comprend les étapes consistant à surveiller une communication entre un distributeur automatique et son système de paiement d'une manière homogène, sans intervenir dans cette communication, puis à procéder au téléchargement en aval automatisé de ces données; à transmettre les données téléchargées par l'intermédiaire d'un réseau sans fil au moyen d'une ressource sous forme de dispositif périphérique externe/modem du dispositif selon la présente invention; à analyser ces données en déterminant des événements et des événements ponctuels, puis à produire des états en homogénéisant la signification d'une communication entre un distributeur automatique et ses systèmes de paiement, communication mise en œuvre selon une multitude de protocoles de communication standard; à extraire, parmi les données analysées, des informations relatives à un état technique d'un distributeur automatique ou de systèmes de paiement, au mode de fonctionnement du distributeur automatique, aux ventes réalisées par le distributeur automatique et aux recettes de ses systèmes de paiement, et à exécuter une commande à distance sur la base des données analysées et éventuellement à interrompre/restaurer le fonctionnement du distributeur automatique à l'aide du dispositif selon l'invention et à la demande du dispositif périphérique externe connecté au distributeur automatique. Les données sont suivies ou surveillées et le diagnostic réalisé sur le distributeur automatique est transféré.
Patent WO-2018170561-A1 (WO)
Title: Procédé de bioremédiation faisant appel à des bactéries, des champignons et des enzymes utilisant comme substrat un milieu constitué d'un matériau cellulosique
Inventor: WALVAG KOLFINN ROGER
IPC: C12R1/01
Filed: 2017-03-22
Abstract: La présente invention concerne un produit élaboré à partir de l'utilisation de bactéries, de champignons et d'enzymes pour la biopolymérisation d'un milieu spécifique constitué d'un matériau cellulosique. L'action de bactéries, de champignons et d'enzymes conduit à des modifications structurales du matériau cellulosique, ce qui permet d'obtenir un matériau possédant un degré de flottabilité élevé et une aptitude à adsorber des contaminants élevée. Par conséquent, le matériau peut être utilisé pour la bioremédiation de molécules carbonées dans des substances liquides et dans des sols, l'agent polluant étant transformé en un composite totalement non toxique pour l'environnement.