baber/WOPTO huggingface dataset:
Patent GB-1153445-A (GB)
Title: A Pentacosapeptide and its preparation
Inventor: GUTTMANN STEPHEN
IPC: C07K14/695
Filed: 1966-05-04
Abstract: 1,153,445. D-Ser<SP>1</SP>-Nle<SP>4</SP>-#<SP>1-25</SP>ACTH. SANDOZ Ltd. 4 May, 1966 [24 Aug., 1965], No. 19725/66. Heading C2C. The pentacosapeptide D-Ser-Tyr-Ser-Nle- Glu(OH) - His - Phe - Arg - Try - Gly - Lys- Pro - Val - Gly - Lys - Lys - Arg - Arg - Pro- Val - Lys - Val - Tyr - Pro - Val - (NH 2 ) (also called D-Ser<SP>1</SP>-Nle<SP>4</SP>-pentacosapeptide), its salts and heavy metal complexes is prepared by removing the protecting groups from the compound N - R<SP>1</SP> - D - Ser - Tyr - Ser - Nle - γ- O - R<SP>11</SP> - Glu - Im - R<SP>111</SP> - His - Phe - Arg- (R<SP>1111</SP>) - Try - Gly - # - N - R - Lys - Pro - Val- Gly - # - N - R - Lys - # - N - R - Lys - Arg- (R<SP>1111</SP>) - Arg - (R<SP>1111</SP>) - Pro - Val - # - N - R - Lys- Val-Tyr-Pro-Val-NH 2 , in which R is carbo-t-butoxy or carbo-(-amyloxy, tosyl, phthalyl, formyl, trifluoroacetyl; R<SP>1</SP> is trityl, carbo-t-butoxy, carbo - t - amyloxy, carbobenzoxy, trifluoroacetyl, acetyl, chloroacetyl or formyl; R<SP>11</SP> is t-butoxy, methoxy, ethoxy, t-amyloxy, benzyloxy or amido; R<SP>111</SP> is trityl, carbo-t-butoxy, carbo-t-amyloxy, carbo benzoxy or benzyl; and R<SP>1111</SP> is nitro tosyl, p-nitrocarbobenzoxy, or 2 - (isopropoxycarbonyl) - 3,4,5,6 - tetrachlorobenzoyl or R<SP>1111</SP> signifies that the guanidino group is protonated, in one or more stages in an acid medium and optionally forming the acid addition or metal salt thereof. The following compounds are prepared as starting materials or intermediates by standard methods: CBO-Arg(NO 2 ) - Arg(NO 2 ) - ProOH, H - Arg(NO 2 )Arg(NO 2 ) - ProOH, 3HBr; CBO - Val - Gly - Lys(CTB) - Lys(CTB) - Arg (NO 2 ) - Arg(NO 2 ) - Pro - OH, CBO - Val - Gly- Lys(CTB) - Lys(CTB) - Arg(NO 2 ) - Arg(NO 2 )- Pro - Val - Lys(CTB) - Val - Tyr - Pro - Val- NH 2  and H - Val - Gly - Lys(CTB) - Lys (OTB) - Arg - Arg - Pro - Val - Lys (CTB)- Val - Tyr - Pro - Val - NH 2 , 3 - TosOHTrit- Glu(OtBu) - (Trit) His - Phe - Arg - Try - Gly- Lys (CTB) - Pro - Val - Gly - Lys (CTB)- Lys (CTB) - Arg - Arg - Pro - Val - Lys (CTB)- Val - Tyr - Pro - Val - NH 2  - 3 - Tos - OH, and H - Glu (OtBu) - (Trit) His - Phe - Arg - Try- Gly - Lys (CTB) - Pro - Val - Gly - Lys (CTB)- Lys (CTB) Arg - Arg - Pro - Val - Gly - Lys- (CTB) - Val - Tyr - Pro - ValNH 2 ; CBO - Tyr- Ser - Nle - OMe and H - Tyr - Ser - Nle - OMe, HCl; CTB - D - Ser - OMe, CTB - D - Ser- NHNH 2 , CTB - D - Ser - Tyr - Ser - Nle - OMe and CTB - D - Ser - Tyr - Ser - Nle - NHNH 2  and CTB-D-Ser-Tyr-Ser-Nle-N 3 . Pharmaceutical compositions comprise DSerl-Nle<SP>4</SP>-pentacosapeptide and an acceptable carrier therefor. The compositions which show a high adrenocorticotropic effect are in a form suitable for parenteral administration without antigenic effects.
Patent GB-638351-A (GB)
Title: Improvements in or relating to reinforced concrete building units
IPC: E04B5/23
Filed: 1946-07-02
Abstract: 638,351. Reinforced concrete beams, floors, &c. JANHUNEN, M. July 2, 1946, No. 19728. [Class 20 (iv)]  A reinforced concrete building unit 2 for floors &c. has a main layer 9 of reinforced concrete with portions of the reinforcing means 5, 3 and 4 extending beyond the upper and lower faces, and a levelling layer 10 on the lower face reinforced by the said reinforcements 3, 4 and of a material of greater density than that of the main layer. As shown the beam 2 has lower reinforcing rods 3, 4 and upper rods 5 connected by hooks 6, and transverse rods 8 are attached to the rods 5 of adjacent units. A floor is formed by mounting the units 2 side by side, filling the joints with hard concrete, and casting a levelling layer 7 over the beams to embed the projecting reinforcements 5, 8. The layer 7 may be of greater density than the layer 9 and harder than the concrete in the joints.
Patent GB-570325-A (GB)
Title: Improvements in or relating to the casting of metals
IPC: B22D18/02
Filed: 1943-11-26
Abstract: 570,325. Casting-machines moulds. PROCTOR, W. F., and WEBB, G. W. Nov. 26, 1943, No. 19742. Addition to 568,303. [Class 83 (i)] In the pressure casting of molten or plastic metal as described in the parent Specification, one or each conduit leading from the metal pot to the die has a removable portion 6 in which is arranged a temporary obstruction 12 adapted to collapse when a desired pressure is attained behind it, i.e. in the conduit 4. The obstruction 12 may be of aluminium, if an aluminium alloy is to be cast, or of other metal or non- metal and may be slightly concave before insertion in its seating 13, being finally flattened to ensure a tight fit. The part 6 may be split to facilitate insertion of the part 12 and may be provided with a well 10 to receive the collapsed part 12. In other respects the part 6 may be shaped and arranged as described in the Specification referred to. If desired, some of the gates may be provided with thinner obstructions 12 or obstructions of different material than the others, or some may be without obstruction so that thicker or other parts of a casting cavity 3 may be filled first.
Patent GB-372159-A (GB)
Title: The manufacture of sulphonated condensation products
IPC: C07C309/34
Filed: 1931-07-09
Abstract: An aromatic or hydroaromatic hydrocarbon or a sulphonic acid derived therefrom is condensed with the residue from the distillation of synthetic methanol, with simultaneous or subsequent sulphonation, if necessary.  Thus, a mono- or poly-sulphonic acid of an aromatic or hydroaromatic hydrocarbon may be condensed with the distillation residue in the presence or absence of an acid condensing agent, or the hydrocarbon and the distillation residue may be simultaneously condensed and sulphonated, or the distillation residue may be mixed with a sulphonating agent and the hydrocarbon then added, with or without an acid condensing agent.  Suitable hydrocarbons are benzene, naphthalene, anthracene, tetrahydronaphthalene, and dihydroanthracene, and suitable sulphonating and (or) condensing agents are sulphuric acid monohydrate, chlorsulphonic acid, oleum, and sulphuryl chloride, or mixtures of any of these.  In the examples, (1) and (2) synthetic methanol distillation residue is mixed with chlorsulphonic acid, and the mixture is introduced into a mixture of naphthalene and sulphuric acid monohydrate, the whole mixture being then heated to 75-80 DEG  C.; (3) tetrahydronaphthalene is sulphonated with sulphuric acid monohydrate, and the product is heated with synthetic methanol distillation residue; (4) the distillation residue is treated with sulphuryl chloride and then with naphthalene and sulphuric acid at a temperature not exceeding 60 DEG C.  The Specification as open to inspection under Sect. 91 (3) (a) states that the distillation residue may first be purified.  This subject-matter does not appear in the Specification as accepted.
Patent GB-357654-A (GB)
Title: Improvements in and relating to fluid-break electric circuit interrupters
IPC: H01H33/55
Filed: 1930-07-01
Abstract: 357,654. Oil-break switches. BRITISH THOMSON-HOUSTON CO., Ltd., Crown House, Aldwych, London.-(Assignees of Hilliard, J. D. ; Hotel Hough, Schenectady, New York, U.S.A.) July 1,1930, No. 19965. Convention date, July 1, 1929. [Class 38 (v).] Fluid-break switches have means for maintaining the oil or other liquid level substantially constant, so that enough air is available in the tank for cushioning and enough liquid to provide proper insulation. A main tank 1 containing the switch communicates through a port 22 with a chamber 21 from which a conduit 25 leads to a reservoir 27. A valve 26 in a chamber 32 communicating with an impeller 30 is controlled by a float 23 so as to allow surplus oil to flow from the tank 1 into the reservoir 27 and to prevent excess oil being transferred by the impeller in the reverse direction. The impeller is driven by a motor 29 under control of an oil-level switch in a chamber 38 which communicates with the main tank. Low oil level causes a float 40 to bridge contacts 43, 44, whereby the motor is caused to replenish the oil supply in the tank 1. If the valve 26 closes owing to the motor failing to stop, an indicator may be actuated or the motor circuit broken from the chamber 32. A vent 28 prevents sudden expulsion of oil from the tank 1. In a simpler form, Fig. 1 (not shown), an overflow pipe leads from the tank to the reservoir and the motor is continuously driven.
Patent GB-885867-A (GB)
Title: Improvements in or relating to the treatment of wool
Inventor: SCHULTE KARL-ERNST
IPC: D06M13/248
Filed: 1960-06-07
Abstract: Wool is shrink-proofed by treating it with an aqueous medium containing a salt of diaminomethane disulphinic acid of the formula <FORM:0885867/IV (c)/1> in which X is Na or N(R1)(R2)(R3)(R4), R1, R2, R3, and R4 being the same or different but each representing an alkyl radical having 1-18 carbon atoms, or of the formula <FORM:0885867/IV (c)/2> in which Y is an alkaline earth metal, and subsequently subjecting it to oxidation.  Salts in which, in formula (a), R1, R2, R3 and R4 are each methyl, or in which, in formula (b) Y is calcium, are preferably used.  The aqueous medium, which may be in the form of a solution, emulsion or suspension and may also contain wetting agents, emulsifiers or buffer agents, preferably contains up to 20% by weight of the salt and preferably has a pH, adjusted with trisodium phosphate, morpholine, triethanolamine or ammonia, of 7-10; it may be used at room temperature or at raised temperatures below 100 DEG C.  After treatment with the aqueous medium the wool may be rinsed with water and then treated with an aqueous solution of an oxidising agent, preferably containing an acid, to reconstitute the keratin chains decomposed by reduction with the diamino methane disulphinic acid salt, or the wool may be exposed to aerial oxidation.  The oxidising and neutralizing agents may be applied to the treated wool in separate steps.  Fibres, yarns, fabrics or articles consisting of or containing wool may be treated.
Patent GB-297188-A (GB)
Title: Improvements in and relating to pocket lighters
IPC: F23Q2/46
Filed: 1927-07-28
Abstract: 297,188. Mitchell, F. B. July 28, 1927. Pocket igniters, frictional.-Means for adjusting the flint comprises a rotatable member having an operating head A surrounding the flint adjacent the friction-wheel B. In one form, a disc i engages a slot in a tube K and is screwed into an internally-threaded tube fixed in the fuel container F. A spring is placed under the flint or a spring washer is provided between the friction-wheel support C and a securing-nut E on the wick-holder N, the movement of the head A of the tube K being limited by a stop C<1> on the support C. A perforated wind-screen may be pivoted at D<1> to the support C. The container F fits in a casing G and is provided with a removable cover. In a modification, the tube K is fixed in the container and the disc i engages an internally-threaded tube carrying the head A, a spring being provided between the lower end of the tube and the bottom of the container. In a second form, the flint is supported in a hollow slotted screw i<22> by a crosspiece i<20> resting on a nut i<23> which engages in a tube P of square cross-section fixed to the upper side of the fuel container o, a spring j being inserted below the screw. The friction wheel B is carried by a wind-screen H having an integral extension H<2> adapted to fit in the space between the fuel container and the casing G.
Patent GB-1141742-A (GB)
Title: Phosphorus-containing esters
Inventor: SCHICKE HANS GERD
IPC: C07F9/6561
Filed: 1966-05-06
Abstract: 1,141,742. Substituted pyrazolo-(1,5-a)- pyrimidines. FABBENFABRIKEN BAYER, A.G. 6 May, 1966 [2 June, 1965; 3 Aug., 1965], No. 20154/66. Heading C2C. [Also in Division A5] Novel compounds of the general formula wherein R and R 1 , which may be the same or different, denote hydrogen atoms or alkyl radicals having 1-3 carbon atoms, R 2  and R 3 , which may be the same or different, are alkyl or alkoxy radicals having 1-4 carbon atoms and R 2  may also be phenyl, Y is an oxygen or sulphur radical, X is hydrogen or halogen and X 1  is halogen, alkylmercapto containing 1-4 carbon atoms or phenyl-, chlorophenyl-, dichlorophenyl-, nitrophenyl- or methylphenylmercapto, are prepared by reacting phosphorus-containing halides of the general formula R 2 R 3 P(Y)Hal where Hal is halogen, preferably chlorine, in the presence of acid binding agents, with pyrazolo-(1,5-α)-pyrimidines of the general formula The process is preferably carried out in the presence of inert organic solvents such as lower aliphatic ketones e.g. acetone or methyl isobutyl ketone; nitriles e.g. aceto- or propionitrile and hydrocarbons such as benzene and xylenes at temperatures between 20‹ C. and the boiling point of the reaction mixture. Suitable acid binding agents include alkali metal alcoholates or carbonates, as well as tertiary amines such as pyridine, triethylamine and diethylaniline. It is also possible to start from the salts, preferably alkali metal or ammonium, of the pyrazolo - (1,5 - α) - pyrimidines and react these with the halides in the absence of an acid binding agent. The products have insecticidal properties. The pyrazolo - (1,5 - α) - pyrimidines are prepared by reacting the appropriate dicarbonyl compounds with the corresponding amino-pyrazolones as follows:
Patent GB-777790-A (GB)
Title: Improvements in and relating to rock drills
IPC: E21B17/04
Filed: 1955-07-12
Abstract: 777,790. Percussive drills. HELLEFORS BRUKS AKTIEBOLAG. July 12, 1955 [July 12, 1954], No. 20208/55. Class 124 A rock drill comprises a drill rod releasably connected to a drill crown having cutting edges and a pilot pin, coaxial with the drill rod, having a head held against an abutment in the crown by the end of the drill. rod and a leading end extending in front of the cutting edges. As shown, a drill crown 1 has a pin 11, formed with a conical part 14 which abuts a conical bore 3 in the crown and an end 12 extending in front of the cutting edges 13, held in position by a rod 9. A bush 5, inserted in. a bore 2 in the crown has a bore which engages part of a parallel portion 15 on the pin and also a part 18 of the drill rod 9. Projections 16 on the rod engage in slots 17 in the bush 5 and the assembly is held in position by a nut 7, threaded on to the bush, which exerts pressure on the end of the bush and on the projections 16 through a resilient packing 20 which may be hard rubber or a spring. In a modification, Fig. 3, the pin may have conical surfaces engaging corresponding surfaces on the crown which is threaded thereon, an extension 24 having a bore and slots to accommodate the drill rod and the projections thereon, and a thread engaging the nut 7. The packing 20 may have steel rings on either side to prevent abrasion. Lengths of drill rod may be conected by a hollow sleeve having slots at either end to accommodate the ends of the rods and their projections, and nuts and resilient washers, Fig. 6 (not shown).
Patent GB-1028751-A (GB)
Title: An improved process for producing ferro-manganese and ferro-chromium in a blast furnace
IPC: C21B5/02
Filed: 1961-06-05
Abstract: A method for producing FeMn or FeCr in a blast furnace using a carbonaceous reducing agent and slagging agent, with or without added scrap or other metal bearing material, includes the step of injecting into the reaction zone during the smelting process, lime or other basic slag forming reagents, with or without fluxes in order to increase the ratio of basic to acidic slag constituents to a value in excess of 1.6:1 and calcium carbide or other carbonaceous material (e.g. coal dust).  The slag forming materials may be lime, dolomite, alumina or fluorspar.  The additional materials, which are preferably preheated, are added in a fluidized form through tuyeres which may be conventionally placed or may be in the furnace bosh.
Patent GB-184788-A (GB)
Title: A method of preventing bleeding in the operation of degumming raw silk in presence of silk dyed with vat-dyestuffs
IPC: D01C3/02
Filed: 1922-07-24
Abstract: 184,788. Soc. of Chemical Industry in Basle. Aug. 13, 1921, [Convention date]. Degumming silk.-Silk fabrics containing raw silk interwoven with silk dyed with vat dye-stuffs are prevented from bleeding during degumming by the addition of a small proportion of a persulphate to the bath. Silk dyed with ciba violet B is boiled with 10 times the quantity of raw silk for two hours in a bath containing per litre 15 grams of Marseilles soap and 2 grams of potassium persulphate.
Patent GB-1464574-A (GB)
Title: Apparatus for securing the free end of a roll of paper or  plastics material to the roll
IPC: B65H19/29
Filed: 1974-05-08
Abstract: 1464574 Securing web ends to rolls WINDMOLLER & HOLSCHER 8 May 1974 [9 May 1973] 20288/74 Heading B8R The free ends of successively delivered rolls of paper or plastics material are secured to the rolls by application of cut lengths of adhesive tape which exceed the circumference of a roll. In the operation of the apparatus shown, the rolls 2 formed by winding apparatus (not shown) are moved singly on endless belts 5, 6 and 7 of a conveyer 1 to a taping station 3 with the loose end 45 of the roll leading. The roll 2 is thrown by way of roll 8 into a gap between continuously rotating rolls 9 and 10 and is rotated thereby so that the end 45 is wound on to its roll. An endless conveyer 41 (in the form of a coil of spring wire) is then set in motion by motor 39 driving roll 38 to move adhesive tape 30 from a supply roll 28 around rollers 37 and 32, across a table 33 and into the gap between roll 2 and supporting roll 9 whereupon a required length of tape is detached by a cutter blade 35 (secured to a pivotable carrier 34 and actuated by pneumatic piston-and-cylinder device 36) and the advance of tape 30 is halted. When the cut length of tape has been wound around, and pressed against, roll 2 by a full revolution thereof, the roll 10 is swung into position 10<SP>1</SP> so that the gap between rolls 9 and 10 widens sufficiently to allow roll 2 to fall therethrough on to a removal shoot. A reserve roll of tape, as at 28, in a holder, as at 29, (not shown) may be available so that its leading end may be gummed to the end of roll 28 about to be depleted. Rolls 9 and 10 are driven from a motor 13 through pulley 11, belt 12, adjustably tensioned by device 14, and belt or chain 21, tensioned by spring- loaded roller 22. Roll 10 is moved to and from position 10<SP>1</SP> by pneumatic piston-and-cylinder device 27 acting through levers 26 and 29, mounted on a shaft 18. The sequence of operations, initiated by a travelling roll 2 engaging the contact arm 46 of a switch, is electrically controlled, in accordance with the frequency of travel of rolls 2 on conveyer 1, by a system including pre-set, time-delay relays, Fig. 3 (not shown).
Patent GB-398983-A (GB)
Title: Improved apparatus for centrifugally moulding concrete pipes and other tubular bodies
IPC: B28B21/30
Filed: 1932-07-18
Abstract: 398,983. Moulding concrete pipes in centrifugal machines. WILLIAMS, R., 19, Bligh Street, Sydney, Australia. July 18, 1932, No. 20297. [Class 87 (ii).] In centrifugal moulding-apparatus for manufacturing concrete pipes and the like of the kind in which the pipe mould is inserted into a tubular casing or carrier supported between rollers for rapid rotation, the rollers are adjustable radially to hold the carrier securely without lateral vibration during its rotation, thus enabling high speeds to be used. In the illustrated form a two-part pipe mould assembled by bolts 25 is placed in the rotary carrier 18, the bolts fitting into recesses 26 so as to form a positive driving connection between the mould and the carrier. The latter carries recessed hardened bearing rings 17 running loosely in U-shaped standards 3 and engaged and supported by eccentricallymounted rollers 15 running on ball or roller bearings. In operation the concrete is placed in the mould and the latter then placed in the carrier and rotated by means not shown. A brake shoe 37 applied by a hand-lever stops the rotation when desired. Packing-pieces 8, together with the eccentric mounting of the rollers 15, permit the rotary pipe to be held securely without rattling or lateral vibration. The pipe may also be centred accurately by independent adjustment of the rollers. The mould may have a socket-forming core at one end connected to the main portion by a bayonetjoint or by fly-nuts. The formed pipe may be trowelled by known means before removal from the machine. The standards may be arranged to form lubricating chambers round the rollers 15 which may be supplied through lubricating- devices 40.
Patent GB-1536756-A (GB)
Title: Method and apparatus for temperature-processing of a product contained in containers
IPC: A01J13/00
Filed: 1976-05-17
Abstract: 1536756 Heating and cooling products in containers GIZEH WERKE GmbH 17 May 1976 [16 May 1975 29 April 1976] 20313/76 Headings F4H and F4U  Products in containers 12 to be heated or cooled, e.g. milk or cream, are received in buoyant stacking boards 13 and floated in a bath W of heat exchange liquid. The bath is formed in a trough 1 supplied with the liquid at one end and removed at the other to aid flow of the boards, the liquid being recirculated through a heating or cooling means and a liquid portion may pass to upper spray devices 15. The boards are formed with cavities K to assist flotation and a shaking means is arranged on the device to agitate the products in the containers and to drive the boards along the length of the bath.
Patent GB-1465024-A (GB)
Title: Wheelchair hub brake
IPC: F16D49/04
Filed: 1975-05-14
Abstract: 1465024 Hub brakes for wheelchairs EVEREST & JENNINGS Inc 14 May 1975 [3 June 1974] 20353/75 Heading F2E A plate 20 forming part of the hub of a wheelchair wheel has an annular recess 18 containing an annular friction lining 19 surrounded by a helical rectangular section spring, one end 22 of the spring being anchored and the other, 23, being movable by rod 15 to tighten the spring about the lining to brake the wheelchair. Rod 15 is pulled by rearwardly rotating a handlever 17 having an over-centre action; if the rod is connected to the lever at 33 rather than 30 the brake will be actuated by pushing the lever forwardly. The other main wheel of the chain may also be provided with a brake of the above type.