baber/WOPTO huggingface dataset:
Patent CA-2540895-C (CA)
Inventor: ELLIS DAVID J
IPC: A61K31/195
Filed: 2004-10-01
Granted: 2016-08-02
Abstract: The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivicaine, clonidine, hydromorphone, baclofen, fentanyil, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the .omega.-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A  preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivicaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil.
Patent CA-2543468-C (CA)
Title: Autonomous garment with active thermal control and powered by solar cells
Inventor: NUNES RAMOS DE CARVALHO BRUNO MANUEL
IPC: A41D1/00
Filed: 2004-10-13
Granted: 2012-07-24
Abstract: The invention refers to an autonomous system and to a method that allows the active thermal control of garments using solar cells as the power source. In the simplest configuration, the system includes a piece of clothing with solar cells (1), a thermal module able to generate heat and cold (3, 4, and 5), and a unit for controlling and monitoring the internal environment (6). In order to increase versatility and to optimize operation conditions, the system includes batteries (2) that can be charged by the solar cells or externally, increasing energy autonomy and improving performance in low radiation conditions. Proper distribution of electric resistors (3) and refrigeration pipes (7) allow a fine-tuning regulation of temperature inside the garment.  The garment is developed not only for standard conditions but also for extreme heast and cold environments, being optimised wither for standard solar radiation or other relevant spectral source.
Patent CA-2548866-C (CA)
Title: Operations cordonnees de gestion de stockage dans un environnement de duplication
Inventor: COLGROVE JOHN A
IPC: G06F11/14
Filed: 2004-12-30
Granted: 2016-07-05
Abstract: L'invention porte sur un procédé, un système, un système informatique et un support lisible par ordinateur permettant de maintenir à jour des copies conformes de données primaires sans devoir reproduire les données modifiées pendant la duplication lorsqu'elles l'ont été suite à une opération n'étant pas une opération d'écriture, non liée à une application, capturée pendant la duplication. Des opérations de gestion sélectionnées sont exécutées sur les stockages de données primaire et secondaire à des instants où les données sont identiques pour garantir que les données des stockages de données restent conformes. Lesdites opérations de gestion incluent des opérations produisant une modification des données du premier stockage, une partie des données modifiées n'étant pas reproduites dans le noeud secondaire. D'autres types d'opérations de gestion, sélectionnées pour être exécutées dans le stockage primaire et dans le stockage secondaire, ne modifient pas directement les données du stockage primaire, mais peuvent modifier celles du stockage secondaire.
Patent CA-2561297-C (CA)
Title: Semiconductor physical quantity sensor of electrostatic capacitance type and method for manufacturing the same
Inventor: MESHII RYOSUKE
IPC: G01L1/14
Filed: 2005-12-12
Granted: 2011-07-12
Abstract: In a semiconductor physical quantity sensor of electrostatic capacitance type, mutually facing peripheral areas (bonding areas) of a glass substrate and a silicon substrate are contacted for anodic bonding, while at the same time, both substrates have an anodic bonding voltage applied therebetween so as to be integrated. A fixed electrode is formed on a bonding face-side surface of the silicon substrate, while a movable electrode is formed on a bonding face-side surface of the semiconductor substrate. An equipotential wiring, which short-circuits the fixed electrode to the movable electrode as a countermeasure to discharge in anodic bonding, is formed on the bonding face-side surface of the glass substrate inside the bonding area before the anodic bonding. After the anodic bonding, the equipotential wiring is cut and removed. By manufacturing the sensor in this manner, the fixed electrode of the insulating substrate is made equipotential to the movable electrode of the semiconductor substrate when the insulating substrate is anodically bonded to the semiconductor substrate, thereby preventing discharge from occurring. Accordingly, it is possible to obtain a high bonding strength and desired sensor characteristics without causing bonding voids to occur and a sensor chip to increase in size.
Patent CA-2562543-C (CA)
Title: Hydrogen peroxide production in microchannel reactors
Inventor: TONKOVICH ANNA LEE Y
IPC: C01B15/01
Filed: 2005-04-27
Granted: 2011-04-19
Abstract: The present invention includes methods and apparatuses that utilize microchannel technology and, more specifically in exemplary form, producing hydrogen peroxide using microchannel technology. An exemplary process for producing hydrogen peroxide comprises flowing feed streams into intimate fluid communication with one another within a process microchannel to form a reactant mixture stream comprising a hydrogen source and an oxygen source such as, without limitation, hydrogen gas and oxygen gas. Thereafter, a catalyst is contacted by the reactant mixture and is operative to convert a majority of the reactant mixture to hydrogen peroxide that is withdrawn via an egressing product stream. During the hydrogen peroxide chemical reaction, exothermic energy is generated. This exothermic energy is absorbed by the fluid within the microchannel as well as the microchannel itself. In a preferred embodiment, a heat exchange fluid is in thermal communication with the microchannel housing the exothermic reaction and is operative to absorb a portion of this exothermic energy and transfer such energy from the microchannel.
Patent CA-2567303-C (CA)
Title: Serveur pour acheminement de connexion vers dispositif client
Inventor: ISHIDA ATSUKI
IPC: G06F13/00
Filed: 2005-05-20
Granted: 2015-03-24
Abstract: [PROBLÈMES] Fournir un système de connexion Internet capable d'établir une communication bidirectionnelle entre un réseau familial et Internet par des moyens comparativement simples et permettant au constructeur du dispositif électrique du réseau familial du client de trouver une valeur ajoutée unique. [MOYENS DE RÉSOUDRE LES PROBLÈMES] Méthode de connexion d'un dispositif client à un serveur comprenant: phase (a) fournir l'adresse IP du serveur à un relais, phase (b) le relais établit une session TCP/IP par une connexion tunnel entre le relais et le serveur en utilisant l'adresse IP fournie, et phase (c) en fonction de l'information sur le relais ou sur le dispositif client, le serveur unifie plusieurs relais ou dispositifs client pour lesquels une connexion tunnel est établie avec le serveur dans le groupe.
Patent CA-2570415-C (CA)
Title: An improved process for the preparation of 5,6 -dihydro -4h-4(s)-ethylamino-6(s)-methylthieno[2,3-b] thiopyran-2-sulfonamide- 7,7 -dioxide and its salt
Inventor: CHANDAVARKAR ANAND MOHAN
IPC: C07D495/04
Filed: 2005-07-06
Granted: 2012-04-17
Abstract: The present invention relates to resolution of (cis, trans) 5,6 -dihydro -4H-4-ethylamino-6-methylthieno[2,3-b] thiopyran-2-sulfonamide-7,7 -dioxide using dibenzoyl -L- tartaric acid monohydrate or di-p-toluoyl-L-tarrtaric acid monohydrate as a chiral resolving agent in presence of methanol to obtain hemitartarate salt, purifying it to obtain hemitartarate salt of 5,6-dihydro-4 H-4 (S) -ethyl amino-6(S) methylthieno [2,3-b] thiopyran-2-sulfonamide - 7,7 -dioxide with de of >99% , Chemical purity >99.5% with cis isomer content of <0.1 % and further converting into its pharmaceutically acceptable salts, preferably hydrochloride salt.
Patent CA-2572508-C (CA)
Inventor: PATEL RAJNIKANT
IPC: C07C269/04
Filed: 1996-08-02
Granted: 2010-03-30
Abstract: The present invention provides an improved process for preparing (S)-4-([3-[2- (dimethylamino)ethyl]-1H-indol-5-yl]methyl}-2-oxazolidinone which comprises: a) forming a carbamate of formula (III), from methyl 4nitro- (L)-phenylalaninate hydrochloride; b) reducing the compound of formula (III) to give the compound of formula (IV); c) reducing the methyl ester grouping in the compound of formula (IV) to give the compound of formula (V); d) ring closure of the compound of formula (V) to give the compound of formula (VI); e) diazonium salt formation from the compound of formula (VI) followed by reduction to give the compound of formula (VII); f) Fischer reaction of the compound of formula (VII) to give (S)-4-{[3-[2- (dimethylamino)ethyl]-1H-indol-5-yl]methyl}-2-oxazolidinone.
Patent CA-2577504-C (CA)
Inventor: MAY DARRELL
IPC: H04W4/00
Filed: 2007-02-07
Granted: 2010-11-02
Abstract: A method for notifying a client device of termination of at least one service provided to the client device by a server system within an enterprise network is disclosed. The method includes the step of establishing authentication data and notification data, where the authentication data is related to the notification data, and sending the authentication data to the client device for storage during a provisioning operation. When the server system identifies a termination of service, it sends the notification data to the client device, which may then authenticate the received notification data using the authentication data.
Patent CA-2578826-C (CA)
Title: Process for the preparation of polyol polymer dispersions
Inventor: SIMROTH DONALD W
IPC: C08G65/26
Filed: 1996-10-28
Granted: 2011-01-25
Abstract: Polymer polyols and polymer-modified polyols having substantially no transition metal content in the polyol continuous phase may be prepared from encapsulative double metal cyanide complex-catalyzed polyoxyalkylene polyether base polyols without substantial removal of double metal cyanide complex catalyst residues from the base polyol and subsequent in situ polymerization of one or more polymerizable monomers.
Patent CA-2579895-C (CA)
Title: Dispositif de mesure de l'urine avec drain ameliore
Inventor: SALVADORI LAWRENCE
IPC: A61M1/00
Filed: 2007-02-23
Granted: 2015-06-30
Abstract: Un uromètre est proposé pour utilisation dans un système de recueil durine. Luromètre comprend un boîtier qui définit au moins un réceptacle de fluide et qui comprend une paroi supérieure concave avec des première et seconde extrémités et une partie centrale dune hauteur réduite. Le boîtier définit des premier et second orifices de drain positionnés adjacents aux extrémités de la paroi supérieure. Le boîtier définit également un orifice dentrée qui sétend au travers de la partie centrale de la paroi supérieure. Un tube de drain avec une extrémité de sortie est positionné au travers de lorifice dentrée pour diriger le fluide dans le réceptacle à fluide. Le tube de drain présente une surface intérieure avec sensiblement aucune discontinuité. Dans un mode de réalisation, le boîtier définit un premier réceptacle à fluide situé au centre et un second réceptacle à fluide positionné autour du premier réceptacle à fluide.
Patent CA-2586449-C (CA)
Inventor: UCHIDA YUKIO
IPC: C07D261/04
Filed: 2005-12-19
Granted: 2012-04-24
Abstract: La présente invention concerne un procédé permettant de produire aisément, de manière sûre et avec un rendement élevé des sels de (4,5-dihydroisoxazol-3-yl)thiocarboxamidine sans les inconvénients de la technique antérieure. L~invention concerne spécifiquement un procédé de production de sels de (4,5-dihydroisoxazol-3-yl)thiocarboxamidine représentés par la formule générale (2) : (2) [dans laquelle R1 et R2 sont chacun un atome d~hydrogène, un alkyle ou un groupe similaire ; R3 et R4 sont chacun un atome d~hydrogène ou un alkyle ; ou bien R1 et R2, ou R2 et R3, peuvent former un cycloalkyle avec le ou les atomes de carbone auxquels ils sont liés ; enfin, X2 est un halogène ou un reste anionique dérivé d~un acide] par réaction d~un composé 3-halogéno-4,5-dihydroisoxazole représenté par la formule générale (1) : (1) [dans laquelle R1, R2, R3 et R4 sont tels que définis précédemment et X1 est un groupe halogéno] avec de la thiourée, en présence d~un acide.
Patent CA-2587332-C (CA)
Inventor: DAVIS ANDREW PETER
IPC: A61B46/23
Filed: 2004-11-30
Granted: 2013-08-06
Abstract: A retracting eye drape assembly is disclosed for use around a patient's eye to seclude and seal off the operative field during eye surgery. The drape assembly includes a retraction member connected to the drape and configured to engage the patient's eyelid, an extension member connected to the retraction member or to the drape and configured to substantially enclose the patient's eyelid, and a retraction flap configured to secure the patient's eyelid in a substantially retracted position. A method of applying an eye drape assembly is disclosed. After application of the drape to the patient's face, and while the patient's eyelid is closed, the patient's eyelid is engaged by a retraction member connected to the drape and retracted. While retracted, the patient's eyelid is substantially enclosed to seclude the eyelid and eyelashes from the operational area. The secluded eyelid and eyelashes are then secured in a retracted position.
Patent CA-2589369-C (CA)
Inventor: MONTE PAUL A
IPC: H04B7/212
Filed: 2007-05-14
Granted: 2015-08-04
Abstract: An improved satellite communication system is provided comprising at least one satellite wherein each satellite provides multiple beams, a plurality of UTs, and at least one gateway connected to a PSTN and communicating with said at least one UT or with a constellation, wherein each of the UTs within a given frequency band is distinguished from another of the UTs employing a combination of TDM and NOPN codes and time slots.
Patent CA-2589819-C (CA)
Inventor: DELACK ELAINE A
IPC: A61K31/4172
Filed: 2007-05-23
Granted: 2015-07-07
Abstract: A method for treatment of multiple sclerosis and other neurodegenerative diseases, disorders or conditions. An alkyl ester of imidazole carboxylic acid, preferably methyl 4-imidazolecarboxylate, is administered in a therapeutic amount. It is hypothesized that the alkyl ester of imidazole carboxylic acid serves to restore and/or maintain the intracellular/extracellular osmolyte gradient in the central nervous system (CNS). The methyl 4-imidazolecarboxylate may be administered transdermally, using PLO gel or other suitable transderamal carrier. The compound may also be administered orally, inhaler or by injection. The treatment is advantageously performed on a three day cycle, with a period of two days intervening between each day on which the compound is administered. Dosage ranges may be from about 0.01 mcg to about 3.0 mcg, with dosages in the range from about 0.1 mcg to about 0.2 mcg in generally preferred when using transdermal administration.
Patent CA-2593494-C (CA)
Title: Dosage a haut debit pour l'inhibition de croissance de cellules cancereuses
Inventor: ABBUD-ANTAKI RULA
IPC: C12Q1/68
Filed: 2006-01-23
Granted: 2013-11-05
Abstract: La présente invention a trait à un dosage à haut débit indépendant d'ancrage qui réalise le criblage de composés pour l'inhibition de la croissance de cellules cancéreuses. Le dosage utilise une matrice tridimensionnelle ou un support semi-solide transfecté avec le composé de l'invention, et permet la détermination et l'imagerie en temps réel de la croissance de colonies.
Patent CA-2594859-C (CA)
Inventor: BROADLEY N KENNETH
IPC: C09J4/04
Filed: 2006-01-10
Granted: 2013-08-13
Abstract: This invention relates to sterilized cyanoacrylate adhesive compositions with x-ray imagining capabilities, methods of making such compositions, and methods of using such compositions.
Patent CA-2598766-C (CA)
Title: Acetic acid production methods incorporating at least one metal salt as a catalyst stabilizer
Inventor: TORRENCE G PAUL
IPC: C07C53/08
Filed: 2006-02-10
Granted: 2012-07-10
Abstract: Processes for the production of acetic acid by carbonylation of methanol, and reactive derivatives thereof, in a reaction mixture using a rhodium-based catalyst system with at least one metal salt catalyst stabilizer selected from the group of ruthenium salts, tin salts, and mixtures thereof are provided.  The metal salt stabilizers minimize precipitation of the rhodium metal during recovery of the acetic acid product, particularly in flasher units in an acetic acid recovery scheme. Stability of the rhodium metal is achieved even when the acetic acid is produced in low water content reaction mixtures in the presence of an iodide salt co-promoter at a concentration that generated an iodide ion concentration of greater than about 3 wt.% of the reaction mixture.  The stabilizing metal salts may be present in the reaction mixtures for the production of acetic acid at molar concentrations of metal to rhodium of about 0.1 :1 to about 20:1. The stabilizing metal salts may be combined with other catalyst stabilizers as well as catalyst promoters.
Patent CA-2601989-C (CA)
Inventor: KOCHEM KARL-HEINZ
IPC: C08L23/00
Filed: 2006-03-16
Granted: 2014-06-17
Abstract: The invention relates to a biaxial oriented film with a microporous layer, comprising a propylene polymer and at least one ~-nucleating agent the microporosity of which is generated by conversion of ~-crystalline polypropylene on drawing the film and the use thereof for the labelling of containers in blow moulding. The Gurley value for the film is 10,000 to 300,000 Gurley.
Patent CA-2607769-C (CA)
Title: Medical diagnosis, treatment and imaging systems
Inventor: BEN-HAM SHLOMO
IPC: A61B5/366
Filed: 1995-01-24
Granted: 2012-04-24
Abstract: A locating system for determining the location and orientation of an invasive medical instrument, for example a catheter (10) or endoscope, relative to a reference frame, comprising: a plurality of field generators (18, 20, 22) which generate known, distinguishable fields, preferably continuous AC magnetic fields, in response to drive signals; a plurality of sensors (30, 32, 34) situated in the invasive medical instrument (10) proximate the distal end thereof which generate sensor signals in response to said fields; and a signal processor (26) which has an input for a plurality of signals corresponding to said drive signals and said sensor signals and which produces the three location coordinates and three orientation coordinates of a point on the invasive medical instrument.
Patent CA-2609177-C (CA)
Inventor: FACCIOLI GIOVANNI
IPC: B01F13/00
Filed: 2006-01-27
Granted: 2013-05-28
Abstract: This invention finds application in the field of the devices and methods for physical or chemical mixing of products and particularly relates to a cartridge for storage and sterile delivery of a two-phase compound. The cartridge comprises a first tubular member (2) which defines a first chamber (3) for storage of a solid phase, having a bottom wall (6) with an opening (7) for the passage of the compound, a second tubular member (9) which defines a second hermetically sealed chamber (12) for storage of a liquid phase, and a piston which sealably slides within the first tubular member (2), means (8) for occluding said opening (7) which comprise at least one rupturable membrane (15) associated to the bottom wall (6).
Patent CA-2611388-C (CA)
Inventor: TABRON IAN STEWART
IPC: A61F5/01
Filed: 2006-06-08
Granted: 2014-09-09
Abstract: L'invention concerne un brassard conçu pour fournir une compression au niveau d'un membre. Ce brassard comporte une paroi externe jointe à une paroi interne pour former une vessie, ladite vessie étant pourvue de dispositifs de séparation des parois de manière à maintenir une voie d'écoulement de liquide dans et hors de la vessie. Cette dernière est caractérisée en ce que les dispositifs de séparation constituent un espaceur situé à l'intérieur d'au moins une paroi qui sépare les parois, lorsque la vessie est dégonflée.
Patent CA-2614786-C (CA)
Inventor: TRUFFERT CATHERINE
IPC: G01V3/38
Filed: 2006-07-11
Granted: 2014-04-08
Abstract: The invention concerns a method for acquiring and processing magnetometric data for representing on an at least two-dimensional map magnetometric characteristics of a geographical zone including a step of measuring the intensity of a magnetic field (1) on a geographical zone producing a set of magnetometric data of intensity B(s), a step of computing 2D interpolation (3), a step of computing reduction at the poles (5) and a step of computing an analytical signal (7). According to the invention, the method includes sectioning the map of magnetic disturbances into a matrix of pixels, a step of locally updating in real time the map of magnetic disturbances, a step of locally updating in real time the map of 2D interpolation by applying the 2D interpolation calculation to the neighbourhood of the updated pixel, a step of locally updating in real time the 2D map of reduction at the poles and a step of locally updating in real time the 2D map of the analytical signal.
Patent CA-2617580-C (CA)
Inventor: CHOI SUN
IPC: C07C4/06
Filed: 2006-06-07
Granted: 2014-02-04
Abstract: Disclosed is a catalytic cracking process for the production of light olefins from a hydrocarbon feedstock using fast fluidization, which is a preferred process for more efficiently increasing the production of light olefin hydrocarbons. According to this invention, a fast fluidization regime is applied to a fluidized bed catalytic cracking process of producing light olefins using zeolite, such that a volume fraction and distribution of the catalyst sufficient to induce the catalytic cracking reaction can be provided, thus effectively enhancing the production of light olefin hydrocarbons, in particular, ethylene and propylene, at high selectivity.
Patent CA-2625454-C (CA)
Inventor: COVARRUBIAS TORRES JUAN PABLO
IPC: E01C11/04
Filed: 2006-07-27
Granted: 2014-04-01
Abstract: The traditional paving systems employed until now, consider the width of pavement slabs equal to a lane width and the long dimension equal to the lane width or 6 meters long. These dimensions make that the vehicles loads, and especially loaded truck, apply the loads at both edges simultaneously, inducing tensile stresses on the slabs surfaces when they are warped. The current invention proposes to built a concrete slab where the maximum width value of slab Dx is being given by the lower measure between the distance D1 of the front wheels of a model loading truck or by de mean, and the distance D2 of a rear running gear of the same truck or the mean; the maximum slab length L is given by the distance between the truck axles or the mean; and the thickness E is given by the concrete resistance value, considering traffic loads, the kind and quality of the base, and the ground type. The current invention comprises the design methodology of this concrete slab, which allows that always only one wheel or only one running gear of the truck, used as model truck or mean, touch and moves over the slab.