baber/WOPTO huggingface dataset:
Patent ES-2035489-T3 (ES)
IPC: G01F23/00
Filed: 1989-09-20
Granted: 1993-04-16
Abstract: In an arrangement for measuring the oil level in the crankcase sump of an internal-combustion engine, in particular for motor vehicles and motor boats with a measuring device, it is envisaged that in each case at least one oil-level measuring device 6, 7 be provided on both longitudinal sides, as seen in the longitudinal direction of the vehicle or the longitudinal direction of the engine, and outside the sump 3, and that the oil-level measuring devices 6, 7 be associated with one another in such a way that the imaginary straight line 43 between them 6, 7 extends in plan view through the centre 44 of the sump 3, that the oil-level measuring devices 6, 7 be arranged at the same level, at the level of the sump 3, that the oil-level measuring devices 6, 7 be connected to the sump 3 in the lower region of the latter by oil pipes 13, 15, 22, 24 in the manner of communicating vessels, in that the oil-level measuring devices 6, 7 form an electrical measured value corresponding to the oil level and that an indicator 35 for indicating the electrical measured value be provided on the dashboard of the motor vehicle or motor boat, which indicator is connected to the oil-level measuring devices 6,7 via electric leads 40, 41, 42. 
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Patent ES-2047097-T3 (ES)
Title: Instalacion para proteger contra pajaros a fachadas o similares.
Inventor: SEIPP REINER
IPC: A01M29/00
Filed: 1989-12-08
Granted: 1994-02-16
Abstract: UN APARATO DE RED (1) ESTA PREVISTO PARA PRODUCIR IMPULSOS DE ALTA TENSION. CON ELLO, HAY UN PRIMER CABLE CONDUCTOR (11) QUE ESTA UNIDO CON LA SALIDA DE IMPULSOS DE LA RED (1) Y UN SEGUNDO CABLE CONDUCTOR DE ELECTRICIDAD UNIDO CON LA SALIDA DE MASA DEL APARATO DE LA RED (1). LOS DOS CABLES ESTAN SITUADOS A PEQUEÑA DISTANCIA, ALGO PARALELOS, POR MEDIO DE AISLADORES (5,15), DE FORMA QUE AMBOS ALAMBRES (11,13) PUEDEN SER TOCADOS POR UN PAJARO. SI ESTA PARTE ESTA ENTERRADA, PARA SU PROTECCION, EL CABLE DE MASA (13) PUEDE QUDAR SUSTITUIDO POR LA SUPERFIE DE LOS ELEMENTOS DE CONSTRUCCION. POR MEDIO DE MUELLES (7) SE TENSAN LOS CABLES, DE FORMA QUE SE IMPIDE QUE HAYA UNA OSCILACION, DE FORMA QUE LOS CABLES O EL ELEMENTO ESTRUCTURAL NO SE PUEDEN TOCAR. ADEMAS, POR MEDIO DE LOS MUELLES (7) SE IMPIDE UNA EXTENSION DE LOS CABLES (11,13). LOS CABLES (11,13) DE UNA FACHADA PUEDEN, POR MEDIO DE LOS AISLADORES, SER APLICADOS A UNA PUBLICIDAD LUMINOSA U OTROS OBJETOS QUE SE QUIERA PROTEGER. COMO APARATODE RED SE UTILIZA UNA APARATO USUAL QUE SE ALIMENTA CON UN PASTOR ELECTRICO.
Patent ES-2050789-T3 (ES)
Title: Metodo de fabricar lactulosa.
Inventor: DORSCHEID MICHAEL
IPC: C07H3/04
Filed: 1989-12-14
Granted: 1994-06-01
Abstract: PARA LA MANUFACTURA DE LACTULOSA, UNA SOLUCION ACUOSA ALCALINA DE LACTOSA Y BORAX ES PREPARADA Y CALENTADA A UNA TEMPERATURA SUPERIOR A 80 C. LA LACTULOSA ES SEPARADA DE LOS PRODUCTOS DE CONVERSION RESULTANTES. APARTE DEL BOROX, NINGUN MATERIAL ALCALIZADOR ES AÑADIDO A LA SOLUCION. LA CONVERSION ES REALIZADA A PH 8.3. EN ORDEN PARA MANTENER LOS IONES DE SODIO EN EL CICLO DE PRODUCCION, EL BOROX DEBE SER MANUFACTURADO EN UNA SOLUCION ACUOSA DE ACIDO BORICO Y SIMULTANEAMENTE CON LA LACTOSA, MIENTRAS LOS IONES DE SODIO SON TRANSFERIDOS DESDE LA SOLUCION DE LOS PRODUCTOS DE CONVERSION EN LA SOLUCION DEL ACIDO BORICO POR ELECTRODIALISIS. ALTERNATIVAMENTE LOS IONES DE SODIO DEBEN SER QUITADOS DE LA SOLUCION DE LOS PRODUCTOS DE CONVERSION TAN RAPIDAMENTE COMO SEA POSIBLE POR MEDIO DE UN CAMBIADOR DE ION DE ACIDO DEBILMENTE Y SOLAMENTE DESPUES DE ELLO POR MEDIO DE UN CAMBIADOR DE ION DE ACIDO MAS FUERTEMENTE. EL CAMBIADOR DE ION DE ACIDO DEBILMENTE ES REGENERADO CON ACIDO BORICO PARA QUE EL BORAXSE FORME DE NUEVO.
Patent ES-2073451-T3 (ES)
Inventor: SMOKVINA TAMARA
IPC: C12N15/09
Filed: 1989-05-16
Granted: 1995-08-16
Abstract: The present invention relates to a cloning vector for expressing a DNA sequence coding for a specified protein in an Actinomyces strain, characterised in that it comprises:  . an att attachment sequence, . a DNA sequence coding for an int sequence which is functional in the said strain, and . a DNA sequence coding for the said specific protein and for the members ensuring the expression of the said sequence in the said strain.
Patent ES-2032128-T3 (ES)
Title: Tubo de rayos "x" de foco variable auto-adaptado a la carga.
IPC: H01J35/14
Filed: 1989-06-22
Granted: 1993-01-01
Abstract: SE RESUELVEN LOS PROBLEMAS DE MANTENER EN TEMPERATURA A LA VEZ DEL ANODO (2) Y DEL CATODO (1) REALIZANDO UN CATODO PLANO (7) INSCRITO EN UN DISPOSITIVO (8) DE FOCALIZACION GRADUADA. SE DEMUESTRA QUE SEGUN LA FORMA DE ESTE DISPOSITIVO EL CAUDAL TERMICO SOBRE EL ANODO ES CONSTANTE CUALQUIERA QUE SEA LA CARGA DEL TUBO.
Patent ES-2052949-T3 (ES)
Inventor: TREMBLAY PAUL A
IPC: A61K31/28
Filed: 1989-08-22
Granted: 1994-07-16
Abstract: This invention relates to pure single isomers of neoalkyl carboxylic acids and platinum complexes comprising the single isomer neoacids. The use of liposomes incorporating these complexes and used in anti-tumor chemotherapy is also described. A particularly preferred liposomal formulation comprising a saturated phosphatidylcholine is described.
Patent ES-2046576-T3 (ES)
Title: Util para maquinas de formacion de mallas, en especial maquinas tricotosas y de generos de punto.
IPC: D04B35/02
Filed: 1990-04-24
Granted: 1994-02-01
Abstract: PIENSESE EN UNA PIEZA, POR EJEMPLO EN UNA AGUJA DE UNA MAQUINA FABRICADORA DE MALLAS, POR EJEMPLO DE UNA MAQUINA DE COSER. ESTA MAQUINA CONSTA DE UN VASTAGO (1) Y DE AL MENOS UN PIE (2). EL VASTAGO TIENE AL MENOS DOS ACANALADURAS (6,7) SITUADAS EN VERTICAL Y DEL MISMO LADO, ESTAS ACANALADURAS PERMANECEN DENTRO DE LA RANURA GUIA EN LA QUE SE INTRODUCE LA PIEZA CON SU VASTAGO.
Patent ES-2086330-T3 (ES)
Inventor: BUFFO FLAVIO
IPC: B41F5/24
Filed: 1990-05-28
Granted: 1996-07-01
Abstract: Multicolor flexographic machine comprising a plurality of printing units, a robot in close relationship with the printing units and arranged to remove in succession each block-holding roller (12) from its working position on the flexographic machine, to place it on a roller support trolley (95) and to replace it with another block-holding roller (12) available on the roller support trolley (95). A system for presetting the block-holding rollers (12) is provided to obtain correct printing overlap in the machine and is controlled by an actuation unit (16) which governs a contact-separation sequence of the rollers in each printing unit with micrometric adjustment of the roller pressure. Each block-holding roller (12) is held in position free to rotate by automatically opening and closing holding caps (17).
Patent ES-2062283-T3 (ES)
Inventor: HARTRUMPF MATTHIAS DIPL-PHYS
IPC: G01B11/02
Filed: 1990-12-20
Granted: 1994-12-16
Abstract: The appts. to measure the position of a bundle of filaments, emerging at right angles to a spinarette to be blown for cooling and then taken-off, has a light source (1) on a plane at about right angles to the take-off direction, in front of the filament bundle (2). A detector unit is behind the filament bundle (2) at an angle alpha) against the direction of illumination. The angle (alpha) is selected to be such that no direct light from the light source (1) strikes the detector. Pref. a lens (3) is located in front of one of more sensors (4) in the detector unit, and the light dispersed at the filments is measured. The light source (1) delivers pulsed light, or it emits a continuous light which is chopped by a light valve. The light source (1) and the detector unit are about at right angles to the bundle of filaments and the flowing direction. The detector unit contains one or more two-dimensional sensors, and a filter is in front of the detector. One two-dimensional filter has two co-ordinates x', y' which is only transparent in the zone y' = f(x') + delta (x'), where f(x') is a monotone function of x' and delta is half the aperture of the transparent zone at point x', and f(x') = x'2.
Patent ES-2078309-T3 (ES)
Inventor: WARD DEREK ALFRED
IPC: E06B5/16
Filed: 1990-06-12
Granted: 1995-12-16
Abstract: An intumescent fire seal for location about a structure such as a door or door frame comprises an elongate flexible strip (4) of plastics material to one surface of which is secured a brush or blade seal (2) which upstands from that surface. A layer of intumescent material (1) is bonded to at least part of the strip surface.
Patent ES-2078949-T3 (ES)
Title: Fabricacion de dispositivo que comprende un proceso litografico.
Inventor: BERGER STEVEN DAVID
IPC: G03F1/16
Filed: 1990-07-27
Granted: 1996-01-01
Abstract: FABRICACION DE DISPOSITIVOS CON TAMAÑO DE CARACTERISTICAS MINIMAS DE MICRA Y SUBMICRA, QUE SE LLEVA A CABO MEDIANTE PROCESAMIENTO LITOGRAFICO EN QUE INTERVIENE UN FILTRO PLANO FOCAL TRASERO (8). UN TRATAMIENTO DE LA FABRICACION QUE IMPORTA PARTICULARMENTE DEPENDE DE LOS MODELOS DE MASCARA QUE PRODUCEN IMAGENES BASADAS EN LA DISCRIMINACION, COMO ENTRE LA RADIACION DISEMINADA (1B) Y SIN DISEMINAR (1A) MEDIANTE ELECTRONES ACELERADOS. POR EL CAMBIO DE FILTRO ES POSIBLE PRODUCIR DOS MODELOS COMPLEMENTARIOS DE LA MISMA MASCARA.
Patent ES-2085895-T3 (ES)
Inventor: WENZINGER CARL J JR
IPC: G09B9/05
Filed: 1990-09-11
Granted: 1996-06-16
Abstract: A trainee station in a tractor-trailer training apparatus include dummy controls simulating those of a tractor, and a display screen visible from the trainee station. At a remote diorama or terrain model a miniature tractor-trailer is moved atop the diorama in accordance with the operation of the trainee's dummy controls. A plurality of video cameras mounted within the cab of the miniature tractor provide video signals which are displayed on the mentioned screen. The fields-of-view of two of the video cameras embrace miniature rearview mirrors on the miniature tractor, providing realistic views of portions of the trailer as trainee operation of the controls moves the miniature tractor-trailer about the diorama.
Patent ES-2036104-T3 (ES)
IPC: E06B9/60
Filed: 1990-02-23
Granted: 1993-05-01
Abstract: An operating device for a roller blind (1) whose apron (2) moves with a slight inclination and comprising a shaft (3) for rolling and/or unrolling the apron (2) formed from fine slats (4, 5, 6) provided at each of their lateral ends (23, 24, 25) with gripping means formed by openings (26, 27, 28) produced in the said lateral ends (23, 24, 25) and provided with strengthening pieces constituted by an insert (29, 30, 31) laterally inserted into the edge of the fine slats (4, 5, 6) and also having an opening (32, 33, 34) situated in alignment with the openings (26, 27, 28) of the fine slats (4, 5, 6), these gripping means cooperating with cam wheels (40) having a neutral travel between each tooth (38, 39) and placed at each of the lateral ends (41) of a second drive shaft (42) disposed in the forward direction with respect to the rolling and/or unrolling shaft (3), these shafts (3), (42) being held by the lateral flanges (43) of a caisson (44) on which guidance rails (45) end, in which rails slide the lateral ends (23, 24, 25) of the fine slats (4, 5, 6) whose insert (29, 30, 31) comprises near its edge (36) facing the heel (15) of the fine slat (4, 5, 6) means (46) of engagement in the channel (16) of the said fine slat (4, 5, 6) and preventing displacement of the fine slats (4, 5, 6) with respect to their longitudinal axis (47). <IMAGE>
Patent ES-2047349-T3 (ES)
Title: Procedimiento para el transporte, almacenamiento intermedio y aprovechamiento energetico, asi como material, de residuos de todo tipo y dispositivo para la realizacion del procedimiento.
Inventor: KISS GUNTER H
IPC: B09B5/00
Filed: 1991-02-22
Granted: 1994-02-16
Abstract: LA EVACUACION DE MATERIALES, BAJO CONSERVACION DE SU MEZCLA Y ESTRUCTURA DE ADHERENCIA INTIMA SOBRE UNA FRACCION DE SUS VOLUMENES ORIGINALES COMPRENDE, DE ESTA FORMA EN CASO NECESARIO, ALMACENAJE INTERMEDIO Y TRANSPORTE Y SOMETIMIENTO A UNA PIROLISIS. EL CONJUNTO DE LOS PRODUCTOS DE PIROLISIS BAJO ALTA PRESION ES SOMETIDO DE FORMA INMEDIATA SUBSIGUIENTEMENTE A UN TRATAMIENTO DE ALTA TEMPERATURA. DE FORMA COMPACTA LOS PRODUCTOS DE EVACUACION PUEDEN SER COMPRIMIDOS EN ENVASES Y SER SOMETIDOS A UNA BAJA TEMPERATURA PRESION DE PIROLISIS. EN UNA PREPARACION TENIENDO EN CUENTA LA PROTECCION DEL MEDIO AMBIENTE, LOS OBJETOS USADOS, COMO RESTOS DE AUTOMOVILES O SIMILARES, RESULTAN EN PORCIONES DE GRAN VOLUMEN DE CHATARRA QUE SON DIVIDIDOS Y/O APLASTADOS ANTES DE LA INTRODUCCION INTERMITENTE EN LA CAMARA DE PIROLISIS. LOS PRODUCTOS APARECIDOS CON LA PIROLISIS, MATERIAS DAÑINAS CONTENIDAS, SOLIDOS, LIQUIDOS O PRODUCTOS DE PROCEDIMIENTOS EN FORMA GASEOSA, SON CONDUCIDOS A TRAVES DE UNO O MAS BAÑOS FUNDIDOS A LOS CORRESPONDIENTES HORNOS DE ALTA TEMPERATURA. LA CAMARA DE PIROLISIS PUEDE ADMITIR ENVASES CON MATERIALES EVACUADOS Y COMPRIMIDOS QUE HAN LLEGADO A TRAVES DE UNA TUBERIA CALIENTE O UN CANAL CON SU CORRESPONDIENTE HORNO ADAPTADO
Patent ES-2125857-T3 (ES)
Inventor: MANNUSS SIEGRIED
IPC: H01H37/48
Filed: 1991-08-14
Granted: 1999-03-16
Abstract: In the region of a sliding guide (17) of an outer tube (2), a rod sensor (1) has a smooth, bolt-shaped abutment (4) for an inner rod (3) which before the insertion of the inner rod (3) and before the structural connection of the temperature sensor (1) to a switch base (10) is set to a predetermined measure of adjustment (30) by means of a measuring screw (36) against the force of a spring (39) and is connected by means of a welding device (40) or the like rigidly to the outer tube (2). This results in a very precise adjustment in conduction with a simple design. 
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Patent ES-2100205-T3 (ES)
Title: Procedimiento para regenerar arena usada de fundicion.
Inventor: SCHOTT HANS-KLAUS DR-ING
IPC: B22C5/18
Filed: 1991-06-29
Granted: 1997-06-16
Abstract: LA INVENCION SE REFIERE A UN PROCESO PARA LA REGENERACION DE LA ARENA USADA EN UNA FUNDICION, CUYA ARENA DE MOLDE DE ORIGEN CONTIENE AGLOMERANTE INORGANICO COMO MATERIAL DEL MOLDE POR EJEMPLO Y ESPECIALMENTE BENTONITA (= "ARENA USADA INORGANICA") Y/O AGLOMERANTE INORGANICO COMO POR EJEMPLO Y ESPECIALMENTE RESINA FENOL Y/O FURANO (="ARENA DE USO ORGANICO"), DONDE LA ARENA USADA A TRATAR SE IMPREGNA EN AGUA Y A CONTINUACION EN UNA SITUACION O CONDICION HUMEDA SE SOMETE A UN PROCESO DE SECADO TURBULENTO EN CAPA.
Patent ES-2071209-T3 (ES)
Title: Metodo y aparato para calibrar cuerpos metalicos tales como pernos roscados y varillas.
Inventor: GOMES KENNETH
IPC: G01B7/28
Filed: 1991-02-22
Granted: 1995-06-16
Abstract: SE PRESENTA UN METODO PARA CALIBRAR CUERPOS QUE INCLUYE EL SUMINISTRO DE UN CALIBRE (20 O 22 O 24) PARA MEDIR UNA PLURALIDAD DE DIMENSIONES DE CORTE SECCIONAL DE UN CUERPO (30) Y POSICIONAR LA SUPERFICIE DE UN CUERPO CONTRA LA SUPERFICIE DEL CALIBRE. EL METODO SE EJECUTA GRABANDO LA INFORMACION CORRESPONDIENTE A LAS DIMENSIONES A MEDIDA QUE SE MIDEN POR EL CALIBRE, PARA FORMAR UNOS DATOS GRABADOS, Y AVERIGUAR UNA RELACION PREDETERMINADA ENTRE DICHAS DIMENSIONES PARA ESOS DATOS GRABADOS. TAMBIEN SE PRESENTA UN APARATO PARA LLEVAR A CABO DICHO METODO.
Patent ES-2114878-T3 (ES)
Title: Representacion visual por resonancia magnetica.
Inventor: FISHMAN ROYCE SHAWN
IPC: G01R33/28
Filed: 1991-06-14
Granted: 1998-06-16
Abstract: UN METODO PARA EFECTUAR IMAGENES DE RESONANCIA MAGNETICA, CON CONTRASTE PERFECCIONADO, QUE COMPRENDE: (A) SUMINISTRAR UN SUJETO ORGANICO VIVIENTE (1), QUE TIENE UN NUCLEO; (B) SUMINISTRAR NEON ESTABLE AL SUJETO; (C) APLICAR UN CAMPO MAGNETICO (3) AL SUJETO PARA ALINEAR AL MENOS ALGUNOS DE LOS NUCLEOS DEL SUJETO (5); (D) SUMINISTRAR ENERGIA DE RADIO PARA SU ABSORCION Y RE-EMISION POR EL NUCLEO ALINEADO; Y (E) OBTENER DATOS BASADOS EN LA ENERGIA RADIO-EMITIDA PARA PRODUCIR DATOS DE VALOR MEDICO PARA DIAGNOSTICO DEL PACIENTE; Y UNA MEZCLA QUE CONTIENE NEON PARA SU UTILIZACION CON EL METODO.
Patent ES-2071941-T3 (ES)
Inventor: SOURLIER PASCAL
IPC: B22D18/04
Filed: 1991-06-11
Granted: 1995-07-01
Abstract: At each stage of the mould (4), the sum of the areas of the inlet cross-sections of the intermediate channels (30A, 30B) which feed the casting runners (32A, 32B) is markedly smaller than the area of the cross-section of the casting pool. Application to the multi-stage casting of thin-wall castings. <IMAGE>
Patent ES-2069858-T3 (ES)
Title: Modulos de memoria en estado solido y dispositivos de memoria que comprenden dichos modulos.
Inventor: DE GIVRY JACQUES
IPC: H01L25/065
Filed: 1991-12-03
Granted: 1995-05-16
Abstract: MODULO DE MEMORIA QUE COMPRENDE SOBRE UN SUSTRATO (12) DE INTERCONEXION, VARIAS PULGAS DE MEMORIA DE SEMICONDUCTORES DE FORMA ALARGADA CUYAS SALIDAS ESTAN LOCALIZADAS EN LOS EXTREMOS. COMPRENDE AL MENOS DOS PULGAS (14, 16) APILADAS Y CRUZADAS.
Patent ES-2049716-T3 (ES)
Inventor: SUNDQUIST JARL
IPC: B26D7/06
Filed: 1991-03-27
Granted: 1994-07-16
Abstract: An improvement in vegetable cutting machines of the kind comprising a cylindrical feeder (1) which includes a vertically upstanding cylindrical tube (2) and a vegetable press-feed device (3) in the form of a plate (4) which extends perpendicular to the longitudinal axis of the tube (2) and which is linearly movable relative to the tube (2) wherein the plate (4) is carried by a stand arm unit placed parallel with the tube (2) and including an upper stand arm (6) having a downwardly projecting shaft (7), wherein the shaft coacts with a tubular part (8) on a lower stand arm (9), thereby enabling the plate (4) to be swung away from the top orifice of the tube (2) and enable vegetables to be inserted into the tube (2) for disintegration in the machine, and wherein a cutting tool comprising a disc provided with one or more knives is mounted in the vicinity of the bottom orifice of the tube (2). The improvements characterized in that the wall of the lower arm (9) is perforated with an L-shaped slot (12) having a part which extends parallel to the longitudinal axis of the stand arm-unit and which terminated at the upper end (13) of the lower arm (9); in that the shaft (7) of the upper arm (6) is provided with an outwardly projecting peg (14) intended for coaction with the slot (12); in that the upper arm (6) is provided with an outwardly projecting wing (15) or the like which functions to restrict rotational movement of the upper arm (6) to a first position through coaction with a stop (16) ; in that the stop (16) can be moved against the action of a spring force such as to enable the upper arm (6) to be rotated to a second position past the first position, in which second position the peg (14) is positioned so as to be able to run in that part of the L-shaped slot ( 12 ) which extends parallel with the longitudinal axis of the stand arm-unit. <IMAGE>
Patent ES-2061251-T3 (ES)
Inventor: WURZER ERNST
IPC: B29C49/04
Filed: 1991-06-08
Granted: 1994-12-01
Abstract: PCT No. PCT/EP91/01081 Sec. 371 Date May 28, 1992 Sec. 102(e) Date May 28, 1992 PCT Filed Jun. 8, 1991 PCT Pub. No. WO92/05936 PCT Pub. Date Apr. 16, 1992.A plastics processing machine, in particular a blow moulding machine, with mould halves of a first product mould secured to movable mould clamping plates, and separate mould halves of a second product mould clamped onto the mould halves of the first product mould. The machine is operated with the mould halves of the first product mould to produce a first product line. During this operation, the mould halves for the second product mould are removed. The machine is operated with the mould halves for the second product line by attaching these mould halves to the mould halves of the first product mould.
Patent ES-2076543-T3 (ES)
Inventor: SCHWABE KLAUS-PETER
IPC: B01D11/02
Filed: 1991-09-05
Granted: 1995-11-01
Abstract: Described is a dry kava extract with a total kavalactone content of at least 50 % by wt. and a flavokavin content of at the most 0.3 % by wt. The extract is readily soluble in water and has high bio-availability following oral administration. In order to increase the kavalactone content and decrease the flavokavin content of the extract, a method is proposed in which the raw extract is brought into solution and the flavokavin content reduced by cold precipitation or by solvent partition, after which the solution is concentrated to dryness. The dry extract can be used to prepare drugs.
Patent ES-2167312-T3 (ES)
Title: Profarmacos para antagonistas de la colecistoquinina.
Inventor: HORWELL DAVID CHRISTOPHER
IPC: A61K31/405
Filed: 1991-08-29
Granted: 2002-05-16
Abstract: SE PRESENTAN NUEVAS PRO-DROGAS PARA NUEVOS DIPEPTOIDES NO NATURALES DE DERIVADOS TRP-PHE SUSTITUIDOS EN (ALFA) UTILES COMO AGENTES EN EL TRATAMIENTO DE LA OBESIDAD, LA HIPERSECRECION DE ACIDO GASTRICO EN EL ESTOMAGO, LOS TUMORES DEPENDIENTES DE LAS GASTRINA O COMO ANTISICOTICOS. ADEMAS, LOS DIPEPTOIDES SON AGENTES ANSIOLITICOS Y AGENTES ANTIULCEROSOS. LOS PEPTOIDES SON AGENTES UTILES PARA PREVENIR LA RESPUESTA A LA SUSPENSION DE TRATAMIENTOS CRONICOS O CON EL USO DE LA NICOTINA, EL DIAPEZAM, EL ALCOHOL, LA COCAINA, LA CAFEINA O LOS OPIACEOS. LAS PRO-DROGAS SON TAMBIEN UTILES EN EL TRATAMIENTO Y/O PREVENCION DE ATAQUES DE PANICO. TAMBIEN SE PRESENTAN COMPOSICIONES FARMACEUTICAS Y METODOS DE TRATAMIENTO QUE USAN LAS PRO-DROGAS ASI COMO PROCESOS PARA SU PREPARACION Y NUEVOS PRODUCTOS INTERMEDIOS UTILES EN SU PREPARACION. ADEMAS, UNA CARACTERISTICA ADICIONAL DE LA INVENCION ES EL USO DE LOS COMPUESTOS DE PRO-DROGAS EN COMPOSICIONES PARA DIAGNOSTICO.
Patent ES-2080341-T3 (ES)
Inventor: FROST PHILIP
IPC: A61K35/12
Filed: 1991-09-12
Granted: 1996-02-01
Abstract: The invention provides a preparation of tumor cell lines containing an exogenous gene encoding a polypeptide that potentiates the immune response to the tumor, for example, interleukin-2. The invention includes methods for cancer therapy by immunization with the immunopotentiating tumor cell. The invention also provides methodology whereby one can selectively ablate in vitro and in vivo genetically altered cells. A preferred embodiment of this aspect of the invention includes a cell containing a first exogenous gene encoding an immunopotentiating polypeptide and a second exogenous gene encoding a "lethal" or "suicide" polypeptide, preferably under the control of an inducible promoter. Introduction of the second exogenous gene confers the ability to selectively kill the tumor cell by inducing a promoter in operative linkage to the gene encoding the lethal polypeptide to initiate transcription of the polypeptide. Diphtheria toxin or the thymidine kinase of Herpes simplex virus are exemplary lethal genes. An exemplary promoter employed is the 6-16 promoter, which is inducible with low levels of interferon. Methods for using the cells in cancer therapy are also provided.
Patent ES-2084859-T3 (ES)
Inventor: MAGNI AMBROGIO DR
IPC: C08F6/08
Filed: 1992-03-24
Granted: 1996-05-16
Abstract: Described is a selective process for the removal of catalytic residues based on AlCl3 or its complex compounds deriving from the (co)polymerization of olefinic and diolefinic cuts, allowing the production of almost colourless hydrocarbon resins. This process comprises contacting the polymerized mass with organometallic compounds, treating the resulting mixtures with water or aqueous solutions, either acidic or basic, and separating the organic phase, which at this point is without inorganic residues.