baber/WOPTO huggingface dataset:
Patent AU-7460796-A (AU)
Title: Substituted arylalkylamines as neurokinin antagonists
Inventor: REICHARD GREGORY A
IPC: A61P1/00
Filed: 1996-10-28
Abstract: Aralkylamine derivatives of formula (I) and their salts are new: A1 = CH2R6, OR6, NR6R7, SOeR13, (CR6R7)qOR6, (CR6R7)qNR6R7 or (CR6R7)qSOeR13; q = 1-6; A2 = H; or A1+A2 = O, CR6R7, NOR6 or S; Q = R5-phenyl, R5-naphthyl, SR6, NR6R7, OR6 or R5-heteroaryl; T = H, R4-aryl, R4-heterocycloalkyl, R4-heteroaryl, R4-cycloalkyl or R10-bridged cycloalkyl; b = 0-2; b1 = 1-2; X = a bond, CO, O, NR6, SOe, NR6CO, CONR6, OC(O)NR6, OC(S)NR6, NR6C(S)O, C(=NOR6), SO2NR6, NR6SO2, NR6CO2 or OC(O); R4, R5 = 1-3 of H, halo, OR6, OC(O)R6, OC(O)NR6R7, NR6R7, 1-6C alkyl, CF3, C2F5, COR6, CO2R6, CONR6R7, SOeR13, CN, OCF3, NR6CO2R16, NR6COR7, NR8CONR6R7, R15-phenyl, R15-benzyl, NO2, NR6SO2R13 or SO2NR6R7; or adjacent R4 substituents or adjacent R5 substituents can form OCH2O; or R4 = R15-heteroaryl; R6, R7, R8, R8a, R13 = H, 1-6C alkyl, 2-6C hydroxyalkyl, 1-6C alkoxy-1-6C alkyl, R15-phenyl or R15-benzyl or NR6R7 = 5-6 membered ring containing 1-2 of O, S and/or NR19; R9, R9a = R6 or OR6; provided that when R9 = OH, then X = a bond, CO, NR6CO or C(=NOR6); R10 = H or 1-6C alkyl; R15 = 1-3 of H, 1-6C alkyl, 1-6C alkoxy, 1-6C alkylthio, halo, CF3, C2F5, COR10, CO2R10, CON(R10)2, SOeR10, CN, N(R10)COR10, N(R10)CON(R10)2 or NO2; R16 = 1-6C alkyl, R15-phenyl or R15-benzyl; R19 = H, 1-6C alkyl, CON(R10)2, CO2R10, (CR8R9)fCO2R10 or (CR8R9)uC(O)N(R10)2; f = 1-6; u = 0-6; Z = a group of formula (a)-(c): g, j = 0-3; h, k = 1-4, provided that h +g = 1-7; J = (H, H), O, S, NR9 or NOR9; L, L1 = H, 1-6C alkyl, 1-6C alkenyl, CH2-cycloalkyl, R15-benzyl, R15-heteroaryl, COR6, (CH2)mOR6, (CH2)mNR6R7, (CH2)mCO2R6 or (CH2)mCONR6R7; m = 0-4; provided that when j = 0 then m = 1-4; R25 = H, 1-6C alkyl, CN, R15-phenyl or R15-benzyl; R26, R27 = H, 1-6C alkyl, R4-aryl or R4-heteroaryl or R26 = H, 1-6C alkyl, R4-aryl or R4-heteroaryl and R27 = COR6, CONR6R7, COR4-aryl, COR4-heteroaryl, SO2R13 or SO2R4-aryl; R28 = H, (CR6R19)tG or (CR6R7)vG2; t, v = 0-3; provided that when j = 0 then t = 1-3; R29 = H, 1-6C alkyl, C(R10)2SOeR6, R4-phenyl or R4-heteroaryl; G = H, R4-aryl, R4-heterocycloalkyl, R4-heteroaryl, R4-cycloalkyl, OR6, NR7R6, COR6, CO2R6, CONR7R9, SOeR13, NR6CO2R16, NR6COR7, NR8CONR6R7, NR6SO2R13, SO2NR6R7, OC(O)R6, OC(O)NR6R7, C(=NOR8)NR6R7, C(=NR25)NR6R7, NR8C(=NR15)NR6R7, CN, C(O)NR6OR7 or C(O)N(R9)-(R4-heteroaryl), provided that when n = 1 and u = 0 or when R9 = OR6 then G is not OH or NR6R7 and G2 = R4-aryl, R4-heterocycloalkyl, R4-heteroaryl, R4-cycloalkyl, COR6, CO2R16, SO2NR6R7 or CONR6R7. 15 Compounds (I) are specifically claimed e.g: N-(2-(3,4-dichlorophenyl)-3-hydroxy-4-(4-hydroxy-4-phenyl-1-piperidinyl)butyl)-N-methyl benzamide.
Patent AU-7522398-A (AU)
Title: Sulfonyloxadiazolones
Inventor: ASSMANN LUTZ
IPC: C07D271/07
Filed: 1998-04-06
Abstract: PCT No. PCT/EP98/01990 Sec. 371 Date Oct. 13, 1999 Sec. 102(e) Date Oct. 13, 1999 PCT Filed Apr. 6, 1998 PCT Pub. No. WO98/47883 PCT Pub. Date Oct. 29, 1998Novel sulphonyloxadiazolones of the formula in which A represents oxygen, sulphur, -SO-, -SO2- or where R3 represents hydrogen or alkyl, R1 represents optionally substituted cycloalkyl, optionally substituted cycloalkenyl or optionally substituted aryl and R2 represents in each case optionally substituted alkyl, alkenyl, dialkylamino or aryl a process for preparing these substances and their use as microbicides in crop protection and in the protection of materials.
Patent AU-7566901-A (AU)
Title: Linear dead-band-free digital phase detection
Inventor: MATTISSON SVEN
IPC: H03L7/197
Filed: 2001-05-21
Abstract: A phase-locked loop includes a phase detector, a loop filter, a voltage controlled oscillator and a frequency divider arranged such that the phase detector generates a phase detector output signal as a function of a phase difference between the reference clock signal and the feedback signal; the loop filter generates a frequency control signal from the phase detector output signal; the voltage controlled oscillator generates a phase-locked loop output signal that has a frequency that is controlled by the frequency control signal; and the frequency divider generates the feedback signal from the phase-locked loop output signal. The phase-locked loop further includes one or more circuit elements that maintain an operating point of the phase detector such that, for a predetermined range of both positive and negative phase differences between the reference clock signal and the feedback signal, the output signal is generated as a substantially linear function of the phase difference between the reference clock signal and the feedback signal.
Patent AU-7594791-A (AU)
Title: Circuit for evaluating frequency difference
Inventor: DESPERBEN LYDIE
IPC: H04L27/14
Filed: 1991-04-24
Abstract: The present invention relates to an apparatus for estimating frequency offset. 
<??>The apparatus for estimating frequency offset between the carrier wave of a reception signal (R) and a local signal (L), this reception signal having been the subject of a modulation with several phase states and therefore exhibiting a phase comprising a transmission phase shift, a modulation phase shift and a synchronisation phase shift, comprises a demodulation unit for producing samples (E) of the reception signal for which the transmission phase shift is suppressed. It moreover comprises means (12, 13) for detecting the modulation phase shift of these samples so as to suppress it. It also comprises means (16) for producing the average phase of a series of samples, the frequency offset then being estimated by taking the difference of the average phase of two series of samples, referred to the period separating the middle of these series. 
<??>It finds an advantageous application in the area of digital cellular radiocommunication systems. 
<IMAGE>
Patent AU-7638691-A (AU)
Title: Sausage link handling and packaging machine
IPC: B65G47/53
Filed: 1991-05-06
Abstract: receiving individual sausage links (17) from a link forming machine (14) and for transferring them onto a main conveyor (30). These sausage links are transferred in a guided manner whereby to orient them on a predetermined ejecting path (24). When the sausage links arrive at the receiving end (25,26,27) of the main conveyor, they are oriented in a side-by-side transverse alignment relationship (17,11). A transfer device is provided at a transfer station along the main conveyor to transfer a predetermined number of the transversely aligned sausage links off the conveyor and onto a package support element. The package support element with the predetermined number of sausage links thereon are then conveyed downstream of the transfer station for further handling. <IMAGE>
Patent AU-7739881-A (AU)
Title: Waste incinerator and steam generator
Inventor: GUILLAUME PAUL
IPC: F22B31/04
Filed: 1981-11-11
Abstract: This invention relates to methods of and apparatus for treating waste products. The apparatus comprises a furnace 1 and a recuperator 2, the furnace comprising at least one rotary section 4 for combustion and/or pyrolysis of the waste products and a stationary section 3 for guiding the smokes generated in the furnace between said rotary section 4 and the recuperator 2. This latter comprises an arrangement 11 -12 for causing the smokes to flow in a state of heat exchange with a fluid 14 for exploitation of the heat thus recovered. A heat-carrier fluid circuit is also incorporated between the walls delimiting the said stationary section 3 and/or the said rotary section 4 of the furnace and the recuperator 2, in such manner that the heat-carrier fluid may transfer the heat it had absorbed during its passage within the furnace walls to the exploitation fluid in the recuperator.
Patent AU-8065794-A (AU)
Title: Improvements relating to cancer therapy
Inventor: CONNORS THOMAS
IPC: C07K14/195
Filed: 1994-11-04
Abstract: PCT No. PCT/GB94/02423 Sec. 371 Date Jul. 1, 1996 Sec. 102(e) Date Jul. 1, 1996 PCT Filed Nov. 4, 1994 PCT Pub. No. WO95/12678 PCT Pub. Date May 11, 1995A system is disclosed which comprises: (i) a viral vector comprising a nucleotide sequence encoding a nitroreductase, which nitroreductase is capable of converting a prodrug into a cytotoxic drug; and (ii) a prodrug capable of being converted into a cytotoxic drug by the nitroreductase encoded by the vector. The disclosed invention also includes methods for killing cancerous and/or non-cancerous cells using the system described above. Included in the invention are methods for killing cells in vitro by introducing a vector encoding a nitroreductase into the cells, and then by providing a prodrug to the cells growing in vitro. Also included are methods in which cancerous and/or non-cancerous cells are killed in vivo in an animal or human by administering the vector and prodrug directly to cells of the animal or human. The invention further includes methods in which cancerous and/or non-cancerous cells are killed in vivo in an animal or human, by introducing a viral vector encoding a nitroreductase into animal or human cells growing in vitro so that the nitroreductase is produced in the cells, administering the cells to an animal or human subject, and then administering a prodrug to the animal or human, where it is converted into a cytotoxic agent in nitroreductase-containing cells of the animal or human.
Patent AU-8146187-A (AU)
Title: Microbial production human serum albumin
IPC: C12N15/00
Filed: 1987-11-20
Abstract: By means of reverse transcription of mRNA coding for a desired polypeptide, there is obtained a set of overlapping fragments of duplex cDNA, which together correspond to the whole mRNA molecule. The fragments have overlapping regions bearing sites for restriction enzymes, such that cutting and ligation gives DNA corresponding to the polypeptide. This is introduced into a vector in reading frame with a promoter. Transformation of a microorganism enables expression of the polypeptide. The construction via fragments enables large molecules to be made. Thus, human serum albumin (HSA) is produced by E. coil transformed with plasmid pHSAI. This includes DNA made from fragments derived from reverse transcription of mRNA from human liver.
Patent AU-8158898-A (AU)
Title: Improved (enterobacteriaceae) fermentation strains
Inventor: FOWLER TIMOTHY
IPC: C12P7/60
Filed: 1998-06-22
Abstract: Methods are provided for preparing improved fermentation strains of the family Enterobacteriaceae which comprise the steps of eliminating the cryptic plasmid from the progenitor strain thereby creating the improved strain. Methods for reducing the mobilization properties of resident plasmids in an Enterobacteriaceae strain containing a cryptic plasmid are also provided. The present invention provides the nucleic acid sequence of pS, a cryptic plasmid found in Pantoea which can be used to identify the cryptic plasmid in strains of Enterobacteriaceae.
Patent AU-8561891-A (AU)
Title: Process and apparatus for separating at least a component of a gaseous mixture by adsorption
Inventor: BOUDET MICHEL
IPC: B01D53/04
Filed: 1991-10-08
Abstract: Process for separating at least one constituent of a gaseous mixture by adsorption, of the kind where the said gaseous mixture travels in a mass of adsorbent (16) of a plurality of adsorbent masses, with cyclic variation in pressure, the high pressure of the cycle being at least twice the low pressure of the cycle, characterised in that the adsorbent is arranged into a plurality of sectorial masses (11) distributed around and integrally attached to a support shaft (2) rotatable around an axis and in that a gas circulation is ensured in the adsorbent in the radial, centripetal or centrifugal direction, towards manifolds extending lengthwise, one situated on the radially inner side, the other situated on the radially outer side in relation to the said sectorial masses of adsorbent and in that a speed of rotation which is between approximately 2 and 20 revolutions/minute is ensured. 
<??>This process is intended particularly for the production of oxygen from air. 
<IMAGE>
Patent BE-889656-A (BE)
Inventor: FILLIAT D
IPC: B21D41/02
Filed: 1981-07-17
Abstract: 1. Expansion head for an apparatus for flaring up or widening the ends of tubes, comprising essentially a body (1) with shifting means (2-2**1 ) for a chuck (3) the tapering end (3**1 ) of which is acting urgingly within the corresponding bore (5**3 ) of a plurality of independent concentric jaws (5) in the form of sectors interconnected by a retaining elastic means (O) positioned within a circular groove (5**4 ) established underneath the common colla (5**5 ) for each one of the aforesaid jaws (5) in order to constitute the expansion head proper, the collar (5**5 ) of which is abutted within the shouldered bore (4**3 ) of a socket (4) secured at the end of the body (1), characterized in that all the retaining means (O and A) of the jaws (5) are disposed underneath their common collar (5**5 ) to permit an extensive range of dimensions of the jaws (5) with the same socket (4), the elastic but collapsible means (A) of said jaws (5) relative to the bottom of said socket (4) being centered and positioned within a groove (5**7 ) of the aforesaid jaws (5) while protruding alternately from the external diameter of the expansion head (T) for retaining same axially and vertically in combination on the one hand with the lower face (4**4 ) of the socket (4) and on the other hand with the opposite collar (5**5 ) abutted on the inside shouldering (4**3 ) of said socket (4).
Patent BE-905983-A (BE)
Title: Protection circuit for power supply to IC - has Darlington pair connected to reduce voltage across load resistance in response to supply pulse
Inventor: C M RING
IPC: H02H3/20
Filed: 1986-12-19
Abstract: The circuit includes a supply providing to 40 volts (10) with a protective circuit on series with the integrated circuit (12). A resistance (14) is connected in series with a transistor (20), with the connection between the resistor and the collector of the transistor being connected to the base of one transistor (16) of a Darlington pair (16,18). - When the voltage drop across the resistance approaches the conduction threshold of the series transistor, the amplifying pair of transistors act to reduce the voltage across the resistance (24) across which the integrated circuit is connected.
Patent BE-796169-A (BE)
Title: Rotatable furnace - for fusing and refining iron with adjustable position of oxidant gas nozzles
IPC: F27B7/20
Filed: 1973-03-01
Abstract: Scrap or solid or liq. pig-iron is treated in a furnace rotatable about its long axis, with opt. introduction of a fuel, e.g. coke and/or slag-formers, by (1) correctly positioning oxidant-gas nozzles by appropriately rotating furnaces, and fusing the contents, and (2) refining by rotating the furnace so as to position the nozzles appropriately for ther refining operation, whether it be by blowing from the top, bottom or side. For fusion, the furnace may be horizontal. The gas may be industrially pure oxygen, and the nozzle may be just below the metal bath. Fusing and refining performed in same appts., therefore cheap.
Patent BG-98303-A (BG)
Inventor: DONCHEV DONCHO I
IPC: F16L58/06
Filed: 1993-12-15
Abstract: Методът се прилага в строителството за възстановяване на тръбопроводи с
малък диаметър. С него чрез опростени съоръжения се осигурява гладка и плътна
вътрешна повърхност в дълги участъци на тръбопрово да. По метода се почиства
вътрешната повърхност на тръбопровода (1), след което в него се вкарват две групи
гъвкави надлъжни тръби (7), а между тях се разполага надуваем полиетиленов ръкав

(2) в ненад уто състояние. Ръкавът (2) се задънва чрез капаци (3), а пространството
между външните му стени и вътрешните стени на тръбопровода (1) се задънва с други
капаци (8). Опори (12) осигуряват стабилност и а конструкцията. Надуваемият
полиетиленов ръкав (2) се запълва чрез подаване на вода през входяща тръба (4) при
отворена изходяща обезвъздушителна тръба (6) до неговото запълване и изтичане на
вода пр ез обезвъздушителната тръба (6). Тръбата (6) се затваря, а подаването на вода
продължава до достигане на налягане половин атмосфера, след което входящата
тръба (4) се затваря и се подава водоплътният материал (11) през инжекционна тръба

(9) при отворена обезвъздушителна тръба (10). Подаването се прекратява, след като
част от разтвора (11) излезе през отвърстието на обезвъздушителната тръба (10). И
зчаква се циментовият разтвор (11) да набере якост, след което се изпуска водата (5)
Patent BR-0003431-A (BR)
Title: Articulação esférica auto-ajustável com fluìdo
Inventor: NAGAYAMA KIYOSHI ROBERTO
IPC: F16C11/06
Filed: 2000-07-28
Abstract: "ARTICULAçãO ESFéRICA AUTO-AJUSTáVEL, COM FLUìDO". A presente invenção refere-se a articulações esféricas em geral e mais especificamente as que são aplicadas em veículos automotores e são compostas por um pino esférico que é acoplado a dois mancais sendo o conjunto introduzido em uma carcaça que é fixada em uma peça e o corpo do pino esférico fixado a outra peça de modo que as duas peças recebam movimentos angulares e rotacionais proporcionados pelo deslocamento do pino esférico em relação à carcaça de articulação esférica. O mancal superior da articulação esférica é construído com uma bolsa interna que comunica-se com a tampa da carcaça e que por sua vez é conectada a um sistema de pressão acionado a partir do motor do veículo de modo que ao se acionar o sistema de pressão este injeta fluído no interior da bolsa do mancal superior da articulação esférica que, sob pressão conforma o conjunto pino esférico, mancal superior, mancal inferior e carcaça proporcionando ao conjunto a carga de deslocamento entre o pino esférico e a carcaça que é desejada para o fim a que se destina. Importante efeito decorre da invenção, ao permitir que o sistema elimine folgas surgidas pelo uso e causadas pelo atrito entre o pino esférico e os mancais, de vez que ao ser injetado mais fluído na bolsa do mancal superior este provoca nova conformação do sistema, eliminando as folgas, restaurando a carga de deslocamento e aumentando a durabilidade da articulação esférica pelo aumento do tempo de uso.
Patent BR-0007169-A (BR)
Title: Sistema de injeção de combustìvel para motores de combustão interna e processo para injeção de combustìvel no compartimento de combustão de um motor de combustão interna
Inventor: BONSE BERNHARD
IPC: F02M47/00
Filed: 2000-09-19
Abstract: Patente de Invenção: <B>"SISTEMA DE INJEçãO DE COMBUSTìVEL PARA MOTORES DE COMBUSTãO INTERNA E PROCESSO PARA INJEçãO DE COMBUSTìVEL NO COMPARTIMENTO DE COMBUSTãO DE UM MOTOR DE COMBUSTãO INTERNA"<D>. Propõe-se um sistema de injeção de combustível para motores de combustão interna com transmissor de pressão (11), em que o combustível é transportado do suprimento de baixa pressão (7) por meio de um conduto transportador (21) para o bocal injetor (1) e aduzido medidamente em termos de tempo e quantidade por meio de um conduto controlador (9) com a parte de alta pressão (5) da bomba injetora (3).
Patent BR-0013038-A (BR)
Title: Composição e método para incrementar a cura de feridas
Inventor: OBI-TABOT ELIOT T
IPC: A61L15/44
Filed: 2000-03-31
Abstract: "COMPOSIçãO E MéTODO PARA INCREMENTAR A CURA DE FERIDAS". A cura de feridas é incrementada através do contato das superfícies da ferida com um curativo de polissacarídeo de D-glicose obtido através da hidrólise de amido contendo ácido ascórbico, colágeno do tipo I e acetato de alfa-tocoferol. O colágeno do tipo I, e o ácido ascórbido no curativo são os agentes quimiotáticos típicos dos neutrófilos, fibroblastos e células endoteliais. Essas combinações podem estar presentes no curativo tal como um gel. O material da composição pode ser aplicado à ferida como um material em partículas, tal como um pó, ou um material tal como um gel, pasta, dispersão, solução ou xarope. As feridas, particularmente aquelas que ocorrem na pele como queimaduras de segundo e terceiro graus, úldera de estase, lesões tróficas, tais como úlceras de decúbito, cortes graves e abrasões, que são normalmente resistentes ao processo de cura natural, podem ser tratadas com essa composição. A aplicação dessa combinação em feridas abertas acelera bastante a velocidade de cura e reduz a formação de cicatriz. A invenção inclui um artigo útil na terapia para as feridas superficiais, o qual compreende a suspensão de partículas em gaze não aderente e uma fita de bandagem.
Patent BR-0014073-A (BR)
Title: Pirazolopirimidinas como agentes terapêuticos
Inventor: HIRST GAVIN C
IPC: A61P19/02
Filed: 2000-09-15
Abstract: "PIRAZOLOPIRIMIDINAS COMO AGENTES TERAPêUTICOS". A presente invenção proporciona os compostos de Fórmula (I), incluindo os sais farmaceuticamente aceitáveis e/ou os pró-medicamentos dos mesmos, onde G, R~ a~, R~ 2~, R~ 3~ são definidos conforme descrito aqui.
Patent BR-0014386-A (BR)
Inventor: HONDT ERIK D
IPC: A61K39/00
Filed: 2000-09-27
Abstract: The invention provides a monovalent influenza vaccine comprising a low dose of egg-derived influenza virus antigen from an influenza virus strain that is associated with a pandemic outbreak or has the potential to be associated with a pandemic outbreak, in combination with an aluminium adjuvant. The invention also provides vaccine kits comprising a combination of a parenteral and a mucosal influenza vaccine, wherein the combined dose of antigen is no more than the conventional antigen dose. Also provided are methods for preparing the vaccines.
Patent BR-0017179-A (BR)
Inventor: PRESTON DAN A
IPC: H04Q7/32
Filed: 2000-05-15
Abstract: An inband modem for communicating digital data over a voice channel of a telecommunications network comprises:an input for receiving digital data;an encoder for converting the digital data into audible tones that synthesize frequency characteristics of human speech and prevent voice encoding circuitry in the telecommunications network from corrupting the digital data represented by the synthesized audio tones; andan output for outputting the synthesized audio tones to a voice channel of a digital wireless telecommunications network;    wherein the synthesized tones are transmitted to avoid interference with actual voice signals transmitted over the same voice channel.
Patent BR-0101322-A (BR)
Title: Processo de obtenção, composição e uso de um sistema de hormÈnios recombinantes para superovulação em vertebrados e invertebrados
Inventor: SANTOS IVAN CARLOS DOS
IPC: C07K14/59
Filed: 2001-04-06
Abstract: "PROCESSO DE OBTENçãO, COMPOSIçãO E USO DE UM SISTEMA DE HORMÈNIOS RECOMBINANTES PARA SUPEROVULAçãO EM VERTEBRADOS E INVERTEBRADOS". Sistema de associação de hormónios recombinantes espécie-específicos que apresentam funções sinérgicas no processo de ovulação. Esta composição de hormónios, pelo fato de ser capaz de estimular a secreção de FSH pela hipófise e aumentar a expressão dos receptores para o FSH em folículos em crescimento, é utilizada para produzir superovulação em vertebrados e invertebrados com maior eficiência neste processo do que os produtos comercializados atualmente.