baber/WOPTO huggingface dataset:
Patent CA-3067289-A1 (CA)
Inventor: BENSON CHARLES THOMAS
IPC: A61K9/48
Filed: 2015-09-08
Abstract: La présente invention concerne un procédé de préparation dun composé de (S)-(7-cyano-4-pyridine-2-ylméthyl-1,2,3,4-tétrahydro-cyclopenta[b]indo1-2-yl)-ester isopropyl dacide carbamique ou un sel connexe acceptable sur le plan pharmaceutique, et un composé essentiellement pure préparé par le procédé (formule I), qui comprend les étapes de réaction de Zn(CN)2 avec le composé de formule II pour produire le composé de formule III et de réaction du composé de formule III avec le composé de formule IV.
Patent CA-3067540-A1 (CA)
Inventor: SINHA SAURAV
IPC: G06F21/33
Filed: 2018-05-28
Abstract: La présente invention concerne un dispositif informatique qui envoie une demande d'un certificat d'attestation à un service d'attestation conjointement avec des informations concernant le matériel et/ou le logiciel du dispositif. Le service d'attestation traite la demande et vérifie les informations reçues en provenance du dispositif. Après vérification des informations, le service d'attestation sélectionne une paire de clés publique/privée à partir d'une collection de paires de clés publiques/privées réutilisables et génère un certificat d'attestation pour le dispositif et la clé publique de la paire de clés publique/privée. Ce certificat d'attestation est signé numériquement par le service d'attestation et est renvoyé au dispositif. La clé privée de la paire de clés publique/privée sélectionnée est également chiffrée sur un composant sécurisé de confiance du dispositif, garantissant que la clé ne peut pas être volée par un logiciel malveillant et réutilisée sur un autre dispositif, et est renvoyée au dispositif. Le dispositif utilise ce certificat d'attestation afin d'accéder à des parties de confiance, et génère facultativement des paires de clés publiques/privées supplémentaires et des certificats d'attestation.
Patent CA-3069468-A1 (CA)
Inventor: GUDURU RAKESH
IPC: B65D41/02
Filed: 2020-01-23
Abstract: A water purification cap for covering a water bottle is provided. The cap may include a barrel and a shell. The shell may surround a first end of the barrel. The cap may include a charging site. The charging site may be integral to the shell. The charging site may include a positive pole, a negative pole and an RGB ring. The RGB ring may insulate between the positive pole and the negative pole. The RGB ring may display colors that indicate a status of the cap. The cap may include a UV-C LED. The UV-C LED may be proximal to a second end of the barrel. The light emitted from the UV-C LED may be UV-C rays. The UV-C rays may be in the range of 100-280 nanometers. The cap may include a touch sensor. When touched, the touch sensor may activate the UV-C LED.
Patent CA-3072170-A1 (CA)
Title: Natural gas liquid fractionation plant waste heat conversion to simultaneous power and cooling capacities using modified goswami system
Inventor: NOURELDIN MAHMOUD BAHY MAHMOUD
IPC: B01D1/00
Filed: 2018-08-07
Abstract: Certain aspects of natural gas liquid fractionation plant waste heat conversion to simultaneous power and cooling capacities using modified Goswami system can be implemented as a system. The system includes a waste heat recovery heat exchanger configured to heat a buffer fluid stream by exchange with a heat source in a natural gas liquid fractionation plant. The system includes a modified Goswami cycle energy conversion system including one or more first energy conversion system heat exchangers configured to heat a working fluid by exchange with the heated buffer fluid stream, a separator configured to receive the heated working fluid and to output a vapor stream of the working fluid and the liquid stream of the working fluid, a turbine and a generator, wherein the turbine and generator are configured to generate power by expansion of a first portion of the vapor stream of the working fluid, and a cooling subsystem including a cooling element configured to cool a process fluid stream from the natural gas liquid fractionation plant by exchange with a condensed second portion of the vapor stream of the working fluid.
Patent CA-3072856-A1 (CA)
Title: Combination of a mapk/erk pathway inhibitor and a glycosaminoglycan for the treatment of cancer
Inventor: FABRICIUS HANS-AKE
IPC: A61K31/416
Filed: 2018-08-23
Abstract: The invention relates to a negatively charged glycosaminoglycan for use as a medicament for the treatment of cancer, comprising the combined administration of a negatively charged glycosaminoglycan, wherein said glycosaminoglycan is characterised by the absence of the terminal pentasaccharide of Heparin, and an inhibitor of the MAPK/ERK pathway. The invention also encompasses a combined administration of a glycosaminoglycan and a MAPK/ERK pathway inhibitor as a medicament for the treatment of cancer types that exhibit a resistance towards a single MAPK/ERK pathway inhibitor treatment.
Patent CA-3075305-A1 (CA)
Inventor: NANAVATI PAYAL
IPC: A61K31/165
Filed: 2018-09-12
Abstract: N-(6-(((2R,3S)-3,4-dihydroxy butan-2-yl)oxy)-2-((4-fluoro benzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide (compound 4), a known chemokine modulator, in combination with colchicine is useful in the treatment of diseases/conditions in which modulation of chemokine receptor activity, interleukin-1 (IL-1) activity, and/or myeloperoxidase (MPO) activity is beneficial. In particular, provided herein are compositions and methods for the treatment and prevention of such diseases/conditions.
Patent CA-3075783-A1 (CA)
Inventor: BRUCKNER RALPH
IPC: A01N25/34
Filed: 2018-09-12
Abstract: La présente invention concerne un revêtement antimicrobien (10, 10', 10", 10"', 10"") d'un substrat (12), le revêtement étant obtenu (10, 10", 10", 10'", 10"") par application du revêtement (10, 10', 10", 10"", 10"") sur une surface (14) du substrat au moyen d'un procédé de pulvérisation électrostatique et le revêtement contenant au moins un oxyde métallique et/ou au moins un sel métallique. En outre, la présente invention concerne un procédé de pulvérisation électrostatique pour le revêtement d'au moins un substrat (12) par un revêtement antimicrobien (10, 10', 10", 10"', 10""). En outre, la présente invention concerne une utilisation d'un matériau de revêtement pour la production d'un revêtement antimicrobien (10, 10', 10", 10"', 10"") sur la surface d'un substrat (12), le revêtement (10, 10', 10", 10'", 10"") contenant au moins un oxyde métallique et/ou au moins un sel métallique.
Patent CA-3079758-A1 (CA)
Inventor: WALENSKY LOREN D
IPC: A61K38/17
Filed: 2018-12-13
Abstract: This disclosure features structurally-stabilized and/or cysteine-reactive peptide inhibitors for selective targeting of BFL-1, or dual targeting of BFL-1 and MCL-1. Also disclosed are methods of using such structurally-stabilized and cysteine-reactive peptides in the treatment of BFL-1- and/or MCL-1-expressing or -dependent cancers or diseases of cellular excess (e.g., autoimmune or inflammatory conditions). Also provided are combination therapies comprising such structurally-stabilized and/or cysteine-reactive peptides and inhibitors of the DNA damage response pathway, such as an ATM kinase inhibitor, ATR kinase inhibitor, CHKl/2 inhibitor, or PARP inhibitor; or an inhibitor of MCL-1, or a selective inhibitor of BCL-2, or an inhibitor of BCL-2/BCL-XL, for the treatment of BFL-1-expressing or -dependent cancers (e.g., AML), BFL-1 and MCL-1-expressing or -dependent cancers, or diseases of cellular excess (e.g., autoimmune or inflammatory conditions).
Patent CA-3079967-A1 (CA)
Inventor: MA MING
IPC: F21V8/00
Filed: 2017-11-18
Abstract: A bar collimator and backlight system provide collimated light to illuminate a backlight. The bar collimator includes a light guide configured to guide light as guided light and a light extraction feature on a side of the light guide configured to scatter a portion of the guided light out of the light guide as extracted light. The bar collimator further includes a collimation film between the light guide and the backlight, the collimation film being configured to collimate the extracted light. The collimated light has an extent corresponding to a length of an input of the backlight and is configured to serve as an illumination source of the backlight. The backlight system includes the bar collimator and the backlight. The backlight may be multiview backlight.
Patent CA-3080255-A1 (CA)
Inventor: FRISSOK FRANK
IPC: C08J9/232
Filed: 2018-10-25
Abstract: The invention relates to a method for producing dyed foamed particles consisting of an elastomer (E), at least having the steps of providing foamed particles made of at least one elastomer (E) and bringing the particles into contact with a mixture (MF) containing a dye (F) and a carrier liquid (TF), thereby obtaining dyed foamed particles, wherein the carrier liquid (TF) has a polarity which is suitable for a sorption of the carrier liquid into the elastomer. The invention additionally relates to dyed foamed particles which are obtained or can be obtained according to such a method and to the use of the dyed foamed particles according to the invention for producing molded bodies, in particular shoe soles, parts of the shoe sole, bicycle saddles, upholstery, mattresses, underlays, handles, protective films, floor coverings, and components for automobile interiors or exteriors.
Patent CA-3080625-A1 (CA)
Title: Traitement de troubles cutanes
Inventor: FABBRO DORIANO
IPC: A61P17/00
Filed: 2018-11-22
Abstract: La présente invention concerne un composé de formule (I), dans laquelle X1, X2 et X3 représentent, indépendamment les uns des autres, N ou CH ; sous réserve qu'au moins deux éléments parmi X1, X2 et X3 représentent N ; Y représente N ou CH ; W représente H ou F ; sous réserve que, lorsque W représente F, alors X1, X2 et X3 représentent N ; R1 et R2 représentent, indépendamment l'un de l'autre, (i) morpholinyle de la formule (II) dans laquelle la flèche représente la liaison dans la formule (I) ; et dans laquelle R3 et R4 représentent, indépendamment l'un de l'autre, H, C1-C3-alkyle éventuellement substitué par un ou deux OH, C1-C2-fluoroalkyle, C1-C2-alcoxy, C1-C2-alcoxy-C1-C3-alkyle, CN, ou C(O)O-C1-C2alkyle ; ou R3 et R4 forment ensemble un résidu bivalent -R5R6- sélectionné parmi C1-C3-alkylène éventuellement substitué par 1 à 4 F, -CH2-O-CH2-, -CH2-NH-CH2- ou l'une quelconque des structures dans lesquelles les flèches représentent les liaisons dans la formule (II) ; ou (ii) un cycle hétérocyclique saturé à 6 chaînons Z sélectionné parmi thiomorpholinyle et piperazinyle, éventuellement substitué par un 1 à 3 groupes R7 ; où R7 représente, indépendamment en chaque occurrence, C1-C3-alkyle éventuellement substitué par un ou deux OH, C1-C2-fluoroalkyle, C1-C2-alcoxy-C1-C3-alkyle, C3-C6-cycloalkyle ; ou deux substituants R7 forment ensemble un résidu bivalent -R8R9- sélectionné parmi C1-C3-alkylène éventuellement substitué par 1 à 4 F, -CH2-O-CH2- ou -O- CH2CH2-O- ; sous réserve qu'au moins un élément parmi R1 et R2 représente morpholinyle de formule II ; et des promédicaments, des métabolites, des tautomères, des solvates et des sels pharmaceutiquement acceptables correspondants pour une utilisation un procédé de traitement d'un trouble cutané chez un sujet, ledit trouble cutané étant une génodermatose, une anomalie vasculaire ou un trouble cutané choisi parmi la sclérodermie, une maladie du greffon contre l'hôte chronique sclérodermique, le lichen scléreux, le lichen plan, le lichen ruber planus et les cicatrices.
Patent CA-3081867-A1 (CA)
Title: Hydraulic accumulator-based controllable pressure injection device and method
Inventor: LIU SONGYONG
IPC: E21C37/08
Filed: 2018-09-21
Abstract: Provided are a controllable pressure jetting apparatus based on a hydraulic energy accumulator and a jetting method. The jetting apparatus comprises a pressure storage system, a pressure holding system, a sealing system and an injection system. The pressure storage system comprises a front half (4-2) of a pressure cylinder, an annular piston (5) and a middle connection body (7). The pressure holding system comprises an energy accumulator (2), a rear half (4-1) of a pressure cylinder, and a rear end cover (1). The sealing system comprises a hydraulic propulsion cylinder (8), a propulsion piston (9), a front end cover (10), a sealing tube (12), a thickened end part (14) and an expanding rubber tube (13). The jetting system comprises a hydraulic valve body (6) and a jetting gun tube (11). The jetting apparatus can quickly apply pressure to the bottom of a drilling hole in a hydraulic manner, so that rock is broken under tension, thereby improving the excavating efficiency of hard rock.
Patent CA-3082785-A1 (CA)
Inventor: ARBELBIDE MARTIN
IPC: C12Q1/68
Filed: 2020-06-10
Abstract: A novel maize variety designated PH48VD and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety PH48VD with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH48VD through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety PH48VD or a locus conversion of PH48VD with another maize variety.
Patent CA-3087669-A1 (CA)
Inventor: TANUWIDJAJA JESSICA
IPC: A01N43/64
Filed: 2018-12-20
Abstract: The present invention is directed to an herbicidal composition comprising metribuzin, a salting-out agent and polyvinyl alcohol. The present invention is further directed to a method of controlling weeds comprising applying a composition of the present invention to the weeds or an area in need of weed control.
Patent CA-3090943-A1 (CA)
Title: Aminopterine gamma polyglutamique et ses utilisations
Inventor: NIYIKIZA CLET
IPC: A61K9/127
Filed: 2019-02-07
Abstract: L'invention concerne de manière générale des compositions d'aminoptérine gamma polyglutamiques, comprenant des véhicules d'administration tels que des liposomes contenant l'aminoptérine gamma polyglutamique, et des procédés de fabrication et d'utilisation des compositions d'aminoptérine gamma polyglutamiques pour traiter des troubles hyperprolifératifs (par exemple, le cancer) et des troubles du système immunitaire (par exemple, une inflammation et des maladies auto-immunes telles que la polyarthrite rhumatoïde).
Patent CA-3092960-A1 (CA)
Title: Structural osb panels with integrated rainscreen
Inventor: LINE JARROD KEVIN
IPC: E04C2/32
Filed: 2019-02-14
Abstract: A plurality of rainscreen elements or features that are applied to the front or outer face of a structural panel or the weather resistant barrier layer on the structural panel. When an exterior cladding or sheathing product is installed over the structural panel, the rainscreen elements or features provide built-in water flow gaps or channels to facilitate and increase water drainage off the face of the structural panel, thereby minimizing water storage in the space between the structural panel and the outer cladding/sheathing. The rainscreen features are incorporated into the structural panel in-line or during the manufacturing process, and do not require any further work during assembly or construction on-site.
Patent CA-3094063-A1 (CA)
Title: Polyethylene terephthalate alloy having talc
Inventor: RAZEEM MOHAMMED
IPC: C08L67/02
Filed: 2018-05-07
Abstract: A method of forming a polyethylene terephthalate (PET) mixture with talc includes: providing a feed of PET (PET feed); providing a feed of talc (talc feed); mixing the feed of PET with the feed of talc in a mixer at a PET:talc ratio of about 3:1 to about 1:3 to foiiii a PET/talc mixture; and providing the PET/talc mixture as output. A method of forming a Polyethylene Terephthalate (PET) alloy having talc includes:  providing a feed of the PET/talc mixture (PET/talc feed); providing a feed of PET (PET  feed); mixing the feed of PET with the feed of PET/talc in a mixer to form a PET alloy having from about 1% (w/w) talc to about 50% talc (w/w); and providing the PET alloy as output.
Patent CA-3094754-A1 (CA)
Inventor: CLARK SEAN
IPC: B65G1/04
Filed: 2019-03-26
Abstract: Un système de stockage comprend un premier ensemble de rails ou de voies parallèles s'étendant dans un sens X et un deuxième ensemble de rails ou de voies parallèles s'étendant dans un sens Y perpendiculaire au premier ensemble dans un plan essentiellement horizontal pour former un motif de grille comprenant plusieurs espaces de grille; plusieurs piles de contenants sous les rails et agencés de sorte que chaque pile soit située dans une empreinte d'un seul espace de grille; et au moins un dispositif de transport configuré pour se déplacer dans les sens X et/ou Y au-dessus des piles, le dispositif de transport comprenant une unité d'entraînement omnidirectionnelle configurée pour entraîner le dispositif de transport dans le sens X et/ou Y, l'unité comprenant un moyen de roulement essentiellement en forme de boule et un ou plusieurs éléments magnétiques ou électromagnétiques. (Figure 5)
Patent CA-3094910-A1 (CA)
Title: Fluid coolers, heat exchangers, seal assemblies and systems including fluid coolers or heat exchangers and related methods
Inventor: VAN NOESEL RONALD
IPC: F28D7/02
Filed: 2019-04-12
Abstract: Heat exchangers include at least one looped tube having at least one section that is laterally offset from another section of the looped tube. Fluid cooling systems and seal systems may include such heat exchangers.
Patent CA-3097236-A1 (CA)
Title: Siloxanes biocompatibles pour la formulation de micro-organismes
Inventor: HANSEL RENE
IPC: A01N63/00
Filed: 2019-04-12
Abstract: La présente invention concerne des compositions qui contiennent au moins un siloxane et au moins un principe actif microbiologique, des procédés pour leur production, leur utilisation pour le traitement de plantes, de semences ou de sols, leur utilisation en tant que biostimulant ou leur utilisation en tant que complément alimentaire probiotique ou additif pour aliment pour animaux, des compositions destinées à être utilisées comme médicament probiotique, ainsi que l'utilisation du siloxane pour améliorer la stabilité au stockage d'un principe actif microbiologique.
Patent CA-3098616-A1 (CA)
Title: Information transmission method and information transmission apparatus
Inventor: GAO LEI
IPC: H04L5/00
Filed: 2019-04-18
Abstract: Provided in the present application are an information transmission method and an information transmission device. The method comprises: a first terminal device mapping first information to a first time unit and a second time unit; and the first terminal device sending the first information on the first time unit and the second time unit, wherein the first time unit comprises a first symbol containing a first cyclic prefix, and the second time unit comprises at least one second symbol containing a second cyclic prefix; and the length of the first cyclic prefix is greater than the length of the second cyclic prefix, and the length of the first time unit is equal to the length of N of the second symbols in the second time unit that contain the second cyclic prefix. The information transmission method and information transmission device of the embodiments of the present application can keep a symbol boundary position for decoding data unchanged while ensuring device-to-device data transmission.
Patent CA-3099929-A1 (CA)
Title: Isotopically labelled materials for degradation detection
Inventor: MORA NOGUES JULIO
IPC: C08L31/06
Filed: 2019-06-25
Abstract: The invention relates to an isotopically marked material comprising a functional synthetic polymer and optionally a functional additive and to its use in the detection of material contamination or degradation or wear, preferably when said material is an industrial material, a space material or a prosthetic material.
Patent CA-3100298-A1 (CA)
Title: A system of racks for space saving storage
Inventor: MITCHELL ALBERT E
IPC: A47B81/00
Filed: 2020-11-20
Abstract: Abstract A system of racks comprising of at least two racks that can be nested together when they are not in use thereby minimizing the space required for their collective storage. Each rack is comprised of a frame having two or more frame elements linked together by at least one Z-shaped bracket. Each frame element is comprised of two vertical support members linked by a plurality of tray holders at spaced apart distances along the interior side(s) of the vertical support members.  The plurality of tray holders on each of the frame elements linked by a Z-shaped bracket are substantially aligned in the vertical direction thereby forming a set of pairs of tray holders. Each pair of tray holders is configured to receive and support the placement of trays. The trays comprise of a flat base portion with upstanding side edges which may be welded to a wire element to reduce crevices where debris and contaminants may otherwise be trapped and to assist with cleaning of the trays. When the racks are not in use, the trays are removed allowing the racks to nest together along their Z-shaped bracket. TOR_LAW\ 10121329\5 Date Recue/Date Received 2020-11-20
Patent CA-3105565-A1 (CA)
Inventor: ONIS SIMON
IPC: C09D151/08
Filed: 2014-04-28
Abstract: Il est décrit un polymère ou un mélange polymère antimicrobien et antithrombogène, des composés, des revêtements et des matériaux les contenant, ainsi que des articles fabriqués avec ceux-ci ou revêtus de ceux-ci, et des procédés de fabrication de ceux-ci, caractérisés par des propriétés antimicrobiennes améliorées et une adhésion plaquettaire réduite. Des modes de réalisation comprennent des polymères comportant des groupes antimicrobiens et antithrombogènes liés à un seul squelette polymère, un polymère antimicrobien mélangé avec un polymère antithrombogène, et des dispositifs médicaux revêtus du polymère ou du mélange polymère antimicrobien et antithrombogène.
Patent CA-3108576-A1 (CA)
Title: Azeotropic compositions of hfo-1234yf and propylene
Inventor: KOBAN MARY E
IPC: C09K5/04
Filed: 2019-10-02
Abstract: Refrigerant compositions including 2,3,3,3-tetrafluoropropene (HFO-1234yf) and propylene (R-1270) which exhibit near-azeotropic or azeotrope-like behavior. The refrigerant compositions exhibit a low global warming potential (GWP) and are non-ozone depleting. The refrigerant compositions are useful as a heating or cooling fluids in a variety of heating or cooling systems including heat pumps and other heating and cooling loops, in for example the automotive industry.
Patent CA-3111059-A1 (CA)
Title: Novel peptides and combination of peptides for use in immunotherapy against various tumors
Inventor: MAHR ANDREA
IPC: A61P37/04
Filed: 2016-03-24
Abstract: Abstract The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules. Date Recue/Date Received 2021-03-04