baber/WOPTO huggingface dataset:
Patent DK-1874745-T3 (DK)
Inventor: MAJKA ZBIGNIEW
IPC: A61K31/4164
Filed: 2006-01-17
Granted: 2009-12-21
Abstract: The invention relates to a method of treatment and/or prophylaxis of diseases and conditions mediated by peroxysome proliferator-activated receptor gamma (PPARgamma) in a mammal subject in need thereof, said method comprising administration to said mammal a compound of formula (I) or a pharmaceutically acceptable salt thereof in a therapeutically or prophylactically effective amount wherein in formula (I) W represents a COOH group or its bioisosters, or COO-C1-C4-alkyl group; Y represents NH or N-C1-C10-alkyl; Z represents NH, N-C1-C10-alkyl, N-aryl, N-heteroaryl, S, or O; X represents O, S, NH, N-C1-C10-alkyl, N-aryl, NSO2-C1-C10-alkyl, N-SO2-aryl, or N S02-heteroaryl; R1 to R6 each independently represents a hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive. The compounds of formula (I) are the ligands of PPAR-gamma receptor.
Patent DK-1818594-T3 (DK)
Inventor: LYSTBAEK PETER
IPC: B29C63/34
Filed: 2007-02-09
Granted: 2010-07-26
Abstract: The invention which is the subject of the application relates to a means of providing a liner (28) for a conduit or pipeline (12), which liner (28) has a collar (32) at at least one end thereof. Said collar (32) is deformable to allow the liner (28) to pass along the interior of the conduit or pipeline (12) and expands at an opening of the same so as to be pressed against the ends of the conduit (12). In one embodiment the collar (32) is positioned at the opening into a further conduit or pipeline (10) along the length thereof and can be overlaid by a liner (20) for that conduit or pipeline (10) thereby providing a sealed joint between the said two conduits (12,10) or pipelines where they join.
Patent DK-1908696-T3 (DK)
Inventor: SCHMIDT PALLE
IPC: B65D33/20
Filed: 2007-10-03
Granted: 2009-11-30
Abstract: To ensure the adhesiveness and thereby the closing function of a flap (4) on a package (1), the flap is manufactured such that when it is pulled from the package material (3), the adhesive (7) and the welding layer (12) are moved to the package material (3), at the same time as a stamped groove (9) on the package (3) produces a portion (11) which corresponds to the opening (6), and which adheres to the flap (4) and thereby provides the opening (6) on the package.  Hereby, the flap (4) is not adhering after the opening, thereby ensuring the adhesiveness when the package is reclosed, since adhesive (7) is not exposed to touch by the fingers or by the packaged material when this is taken out of the package.
Patent DK-2150299-T3 (DK)
Inventor: KEITEL JOACHIM
IPC: A61M5/315
Filed: 2007-11-05
Granted: 2012-01-30
Abstract: Injection device (30) comprises a housing (42, 52), a container for holding an injection fluid (32), a device for pressing the fluid from the container, a dosing unit (66) which twists relative to the housing and interacts with the outer thread of the pressing device and a coupling arrangement for stopping the first device from rotating relative to the housing (52) during the injection process. Preferred Features: The dosing unit and the pressing device do not twist relative to each other during pre-selection of the injection dose.
Patent DK-2194215-T3 (DK)
Inventor: LEEDER STEFAN
IPC: E04H13/00
Filed: 2008-12-04
Granted: 2011-05-23
Abstract: The urn column consists of a segment (0) with a hollow chamber (1) and a column opening (5) at the upper end area of the column. The urn capsules (2) are arranged in receptacles and are hanged one above the other in the hollow chamber. The receptacles are formed by urn carrier bags (3), in which the urn capsules are wrapped and have height-adjustable carrier loops (4).
Patent DK-2204884-T3 (DK)
Inventor: ZIBUNG WERNER
IPC: H01R4/36
Filed: 2008-12-30
Granted: 2012-07-02
Abstract: The cage terminal has a U-profile shaped cage (23) two legs (11a,11b) and a bar (12) for connecting the legs on a side. The legs have two leg windows (13a,13b). The bar has a threaded bore (26) for receiving a screw (27), by which a conductor (14a,14b) inserted through leg windows is securely clamped.
Patent DK-2397136-T3 (DK)
Inventor: MATHEZ LAETITIA
IPC: A61P29/00
Filed: 2011-06-17
Granted: 2018-07-16
Abstract: Composition comprises Harpagophytum(50-3000 mg) or harpagosides (1-100 mg) and vitamin D (0.5-50 mu g). ACTIVITY : Anabolic; Antiinflammatory; Analgesic; Antiarthritic; Osteopathic; Antiasthmatic; Antiarteriosclerotic; Antirheumatic; Antiallergic; Dermatological; Antipsoriatic; CNS-Gen.; Respiratory-Gen.; Neuroprotective; Antidiabetic; Vasotropic; Nephrotropic; Ophthalmological; Antipyretic; Immunosuppressive; Muscular-Gen.; Antigout. MECHANISM OF ACTION : None given.
Patent DK-2420490-T3 (DK)
Title: A process for the preparation of (+) - 2- [1- (3-Ethoxy-4-methoxyphenyl) -2-methylsulfonylethyl] -4-acetylaminoisoindolin-1,3-dione
Inventor: MULLER GEORGE W
IPC: C07D209/48
Filed: 2003-03-20
Granted: 2016-10-03
Abstract: Discussed is stereomerically pure (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, or a pharmaceutically acceptable polymorph, salt, solvate or hydrate thereof, as well as a pharmaceutical composition or single unit dosage form comprising such compound and such compound for use as a medicine.
Patent DK-2553096-T3 (DK)
Inventor: NAKAMURA YUSUKE
IPC: A61K39/00
Filed: 2011-03-30
Granted: 2018-01-15
Abstract: Isolated peptides derived from SEQ ID NO: 42 and fragments thereof that bind to an HLA antigen and induce cytotoxic T lymphocytes (CTL) and thus are suitable for use in the context of cancer immunotherapy, more particularly cancer vaccines, are described herein. The inventive peptides encompass both the afore-mentioned amino acid sequences and modified versions thereof, in which one, two, or several amino acids are substituted, deleted, inserted or added, provided such modified versions retain the requisite HLA binding and/or CTL inducibility of the original sequences. Further provided are nucleic acids encoding any of the aforementioned peptides as well as pharmaceutical agents, substances and/or compositions that include or incorporate any of the aforementioned peptides or nucleic acids. The peptides, nucleic acids, pharmaceutical agents, substances and compositions of this invention find particular utility in the treatment of cancers and tumors, including, for example, bladder cancer, breast cancer, cervical cancer, cholangiocellular carcinoma, CML, colorectal cancer, esophageal cancer, NSCLC, lymphoma, pancreatic cancer, prostate cancer, renal carcinoma and SCLC.
Patent DK-2636741-T3 (DK)
Title: Induction of exon skipping in eukaryotic cells
Inventor: VAN OMMEN GARRIT-JAN BOUDEWIJN
IPC: C12N15/113
Filed: 2001-09-21
Granted: 2016-07-04
Abstract: The present invention provides a method for at least in part decreasing the production of an aberrant protein in a cell, said cell comprising pre-mRNA comprising exons coding for said protein, by inducing so-called exon skipping in said cell. Exon-skipping results in mature mRNA that does not contain the skipped exon which leads to an altered product if said exon codes for amino acids. Exon skipping is performed by providing a cell with an agent capable of specifically inhibiting an exon inclusion signal, for instance an exon recognition sequence, of said exon. Said exon inclusion signal can be interfered with by a nucleic acid comprising complementarity to a part of said exon. Said nucleic acid, which is also herewith provided, can be used for the preparation of a medicament, for instance for the treatment of an inherited disease.
Patent DK-0380947-T3 (DK)
Inventor: ILLY ERNESTO
IPC: A47J31/56
Filed: 1990-01-13
Granted: 1993-12-20
Abstract: A coffee machine wherefrom a user may optionally request different quantities of coffee as to the volume of beverage and wherein the infusion water temperature in a heater (7) is lowered when the quantity of the requested beverage increases. To this purpose, the machine is provided with a control means assembly comprising a meter (12, 24) for the quantity of water moving to an extraction chamber (3), a temperature transducer (13) for sensing the temperatures the water achieves in the heater (7) and a control means (14) adapted to receive the signals from said meter (12, 24) and temperature transducer (13), and to control, according to a given algorithm, the water temperature in the heater (7) as a function of the moving quantity of water.
Patent DK-0416272-T3 (DK)
Inventor: PANSTER PETER DR
IPC: C02F5/00
Filed: 1990-07-27
Granted: 1993-12-13
Abstract: Die Erfindung betrifft gegebenenfalls mittels Si-, Ti-, Zr- und/oder Al-haltigen Vernetzern vernetztes Organosiloxanamin-Copolykondensat aus Einheiten 
<CHEM>
 R<5> = direkt an N bzw. an X gebundenes Alkylen mit C1-C10, Cycloalkylen mit C5-C8 oder 
<CHEM>
 X = -NH2, -NH-(CH2)2-NH2, -N(CH3)2, -N(C2H5)2 -NH-(CH2)2-NH-(CH2)2-NH2, -Cl, -Br, -J, -SH, -P(C6H5)2, 
<CHEM>
 wobei R sec  = H oder Alkyl mit C1-C3, in Form kugelförmiger Teilchen mit einem Durchmesser von 0,01 bis 3,0 mm, einer spezifischen Oberfläche von 0 bis 1000 m<2>/g, einem spezifischen Porenvolumen von 0 bis 6,0 ml/g sowie einer Schüttdichte von 50 bis 1000 g/l. Sie betrifft weiterhin diverse Herstellungsverfahren für die geformten Copolykondensate sowie eine Verwendung jeweils bestimmter Zusammensetzungen zur Entfernung von Metallen aus Lösungen bzw. zur Adsorption von gasförmigen organischen Verbindungen und/oder von Wasserdampf.
Patent DK-0411631-T3 (DK)
Inventor: CARR ALBERT A
IPC: A61P25/04
Filed: 1990-08-02
Granted: 1994-05-16
Abstract: The present invention is directed to a new class of therapeutic agent of the formula: <CHEM> in which Y is represented by CO or CHOH; T is represented by CO or CHOH; X is represented by hydrogen or a C1-6 alkyl; n is represented by the integer 3 or 4; R and R1 are each independently represented by hydrogen, C1-6 alkyl, C1-6 alkoxy, halogen, -OH or -CF3; and pharmaceutically acceptable acid addition salts thereof, which are useful as anti-psychotic agents and as analgesics.
Patent DK-0409525-T3 (DK)
Inventor: LAMB VERNON LEROY
IPC: B29B17/00
Filed: 1990-07-16
Granted: 1994-10-10
Abstract: Apparatus and process for fabricating pressboard from shredded paper coated with a thermoplastic material and a pair of facing webs includes placing the shredded poly-coated paper (18) between the two travelling webs (12,14) to form a composite, the composite then being passed in a manner to differentially shift the travelling webs relative to each other for enhanced bonding of the shreds to themselves and to the facing webs, by pressing them through a series of heated rollers (46-52) defining a serpentine path while heating the thermoplastic material above its softening point, and pressing the composite together.
Patent DK-0436715-T3 (DK)
Inventor: MUELLER MARC B
IPC: C02F/
Filed: 1990-07-31
Granted: 1995-02-27
Abstract: An improved process for absorbing oils and especially separating and recovering oils from an aqueous medium or aqueous/wetted medium using an absorbent oleophilic biodegradable sponge material comprised of essentially fat-free, foamable natural products, specifically animal proteins or plant polysaccharides, such as gelatin, collagen, egg white albumen, gum agar, gum arabic, gum karaya, and locust bean gum, which absorb oils at a rate of at least about 30 times their weight.
Patent DK-0535110-T3 (DK)
Inventor: KLINGEBERG MICHAEL
IPC: C12N9/52
Filed: 1991-06-14
Granted: 1995-05-15
Abstract: This invention is within the field of thermostable proteases. More specifically, the present invention relates to a thermostable protease from Thermococcus celer, Thermococcus stetteri or Thermococcus litoralis, to a process for the preparation of these enzymes, and to detergent compositions comprising these enzymes. The enzyme has a temperature optimum in the range of from 75 to 100  DEG C and a pH optimum in the range of from 6.0 - 10.
Patent DK-0507154-T3 (DK)
Inventor: SIMON WILHELM PROF DR
IPC: G01N33/98
Filed: 1992-03-19
Granted: 1996-06-10
Abstract: Novel hemiacetals of the formula II <IMAGE>  are described in which     R' is an aliphatic or cycloaliphatic radical, Ar represents an unsubstituted or substituted mononuclear or polynuclear radical having aromatic or heteroaromatic character and, if appropriate, having non-polar, weakly polar or basic substituents and/or chromophoric groups or groups inducing fluorescence or luminescence.   At least one of the substituents X<1>, X<2> and X<3>, preferably all three of the substituents mentioned, must be powerful electron-attracting substituents and are selected from the group of the fluorine atoms, chlorine atoms, bromine atoms or nitro groups, preferably fluorine atoms. The hemiacetals are formed reversibly from the corresponding keto compounds upon contact with an alcohol of the formula R'OH, and during this reaction the absorption of light in the ultraviolet, visible or infra-red range changes, or a fluorescence or luminescence originates or is quenched. Devices containing the keto compounds act as optical sensors for the determination of the alcohols mentioned.
Patent DK-0518233-T3 (DK)
Inventor: JUNKER WILHELM
IPC: E01F9/692
Filed: 1992-06-05
Granted: 1996-06-24
Abstract: The road marking (20) has a number of basic bodies (21) which are coupled to one another in the longitudinal direction one behind another by means of coupling devices. For each basic body (21), at least one reflector bow (23) is present, which is aligned transversely to the longitudinal extent of the basic body (21) and is detachably connected to the basic body (21) by means of a connection device. The reflector bows (23) have on both their end sides a number of reflectors (49) which are permanently connected to the reflector bow. <IMAGE>
Patent DK-0507375-T3 (DK)
Inventor: SNELLEN THEODORUS CORNELIS C M
IPC: G06Q10/00
Filed: 1992-03-16
Granted: 1998-03-16
Abstract: Method of determining free subareas on an area partially covered with rectangular objects and also a method of determining free spaces in a space partially filled with objects in the form of a right parallelepiped, in which method an essentially rectangular area to be covered or a space to be filled is depicted in the form of a two-dimensional or three-dimensional matrix, respectively, each element of the matrix representing a rectangle on the area or a right parallelepiped in the space and it being established for each element whether the corresponding rectangle in the area or the corresponding right parallelepiped in the space is free or occupied, after which the number of rows and columns and, possibly, layers of the matrix is reduced in accordance with a fixed algorithm until the unit matrix has been reached. During the matrix reduction, a search is continuously made for matrix elements which have a first logic value and which are bounded on all sides by elements having a second logic value; such an element indicates the presence of a free space in the (reduced) matrix. A dimension table is also determined for each of the dimensions, the length of each table being linked to the number of rows, columns and, possibly layers, respectively, of the matrix. During the reduction of the matrix, the dimension tables are updated in accordance with a fixed system, with the result that, whenever a free area or a free space is found during the reduction of the matrix, the position of said area or said space can be read off from the table. <IMAGE>
Patent DK-0545550-T3 (DK)
Inventor: MANWELL JOHN
IPC: G07F7/08
Filed: 1992-11-02
Granted: 1996-11-04
Abstract: A prepayment water supply system comprises a prepayment unit having a receptacle for receiving a prepayment token in the form of a key, and a solenoid-operated valve controlled by the prepayment unit for controlling the water supply. The key has a memory containing credit and identification data, and the prepayment unit closes the valve when the credit represented by the credit data is exhausted. However, a bypass passage is provided which permits a supply of water at a relatively low flow rate when the valve is closed, so that enough water for drinking and filling lavatory cisterns (albeit very slowly) continues to be supplied. <IMAGE>
Patent DK-0550744-T3 (DK)
Inventor: CARPENTER CLINT W
IPC: C09D175/04
Filed: 1992-07-21
Granted: 1996-04-22
Abstract: The present invention is directed to a process for the preparation of amine modified copolymers as a pigment dispersant for cathodic electrocoating compositions comprising the steps of a) polymerizing i) an ethylenically unsaturated monomer containing an isocyanate group with ii) other ethylenically unsaturated monomers having no functional group capable of undergoing a reaction with said isocyanate group to form a copolymer with isocyanate groups and b) reacting stepwise or simultaneously said isocyanate groups with iii) a compound selected from the group consisting of a polyalkyleneglycol monoalkyl ether, an aminoterminated polyalkylene glycol monoalkyl ether and mixtures thereof and iv) a compound containing at least a tertiary amine group and one functional group capable of undergoing a reaction with said isocyanate group and v) optionally, another compound having one functional group capable of undergoing a reaction with said isocyanate group.
Patent DK-0556661-T3 (DK)
Inventor: THIHATMER ALFONS
IPC: B66F11/04
Filed: 1993-02-05
Granted: 1997-07-14
Abstract: In order to create a mobile working apparatus, in particular a working lifting platform, which is simple and reliable in the mode of operation and in which automatic and manual locking of the stabilising parts can be carried out in a simple manner, a drawbar (3) and supports (4, 5, 6) can be adjusted by energisable hydraulic cylinders (9.1, 9.3 ...). An energisable locking device (28) is arranged with the hydraulic cylinder (9.1) between receiving elements arranged on the drawbar (3) and a chassis (1) so that the adjustment of the drawbar (3) can be locked and unlocked automatically. <IMAGE>
Patent DK-0604701-T3 (DK)
Inventor: COLLEGE JOHN W
IPC: C01F11/46
Filed: 1993-06-04
Granted: 1999-06-23
Abstract: A method is provided for removing sulfur dioxide from a hot gaseous stream while directly producing  alpha -hemihydrate gypsum from a scrubber effluent. A portion of an aqueous scrubbing medium containing calcium and magnesium sulfite is removed from a scrubbing unit and passed to a pressurized oxidation vessel where the sulfites are contacted with an oxidizing gas at an elevated temperature to convert calcium sulfite directly to  alpha -hemihydrate gypsum and magnesium sulfite to magnesium sulfate. The  alpha -hemihydrate is separated from the aqueous medium removed from the pressurized oxidation vessel.
Patent DK-0660991-T3 (DK)
Inventor: KAUPPI HANNA-MARIA
IPC: H04W68/00
Filed: 1993-09-15
Granted: 2000-04-17
Abstract: In a cellular radio network in which mobile stations roam, in addition to location updating of each mobile station with the accuracy of one location area, a so-called temporary subscriber-specific paging area is determined. Each mobile station initiates the determining of the temporary paging area in the subscriber data base of the cellular radio network after being located in a cell for a sufficiently long period. The temporary paging area is smaller than the location area (e.g., one cell and possibly at least one adjacent cell), and thus the paging of a mobile station can be focused on a small area, i.e., the temporary paging area. It is thus unnecessary to page over the entire location area, and paging time can be reduced and capacity of the cellular radio network spared.
Patent DK-0717731-T3 (DK)
Inventor: VAN DORSSELAER VIVIANE
IPC: A61K38/55
Filed: 1994-08-10
Granted: 1999-11-01
Abstract: This invention relates to novel statone antiviral analogs, to the processes and intermediates useful for their preparation and to their use as antiviral agents.
Patent DK-0725855-T3 (DK)
Inventor: KROYER KARL KRISTIAN KOBS
IPC: D04H1/64
Filed: 1994-10-28
Granted: 1998-05-04
Abstract: A method is disclosed for the use of a modified latex making it possible to provide a combination of hydrogene bonds and covalent bonds in fibrous products. A softener product is added to the binder solution before its application onto the fibrous product. The softener is a natural latex added to a latex binder contained in a water suspension. It has surprisingly shown that a product manufactured with a modified latex will occur more soft and silky and also stronger than products made by use of a normal latex binder. The modified latex is especially suitable for use in a process in which a mechanical softening treatment is effected on the fibrous product.
Patent DK-0710548-T3 (DK)
Inventor: THEIL ALEXANDER
IPC: B32B27/30
Filed: 1995-10-26
Granted: 2000-10-30
Abstract: Lamination of plastics (A) and (B) by thermal bonding of two surface-heated layers (1,1') comprises passing the layers, the surfaces (1a,1a') of which are preheated to surface temps. 10-100 K above the Vicat softening temp. (VST; DIN ISO 306), whilst retaining their original shape, and laminating them between a pair of rollers (2,3), at least one (3) of which exerts pressure (4), at a rate of 5-200 mm/s and pressure of 10-500 N.
Patent DK-0699676-T3 (DK)
Inventor: HARKNESS ALLEN ROBERT
IPC: A61P25/28
Filed: 1995-08-30
Granted: 2001-02-26
Abstract: A physical form of (R)-7-acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxoloÄ4,5 -hÜÄ2,3Übenzodiazepine of formula I having an X-ray powder diffraction pattern with d spacings at 10.61, 8.83, 6.78, 5.83, 4.13 and 3.74  ANGSTROM . The compound is useful as an AMPA antagonist. <CHEM> R is methyl, X is acetyl and Aryl is p-nitrophenyl.i
Patent DK-0726866-T3 (DK)
Inventor: HEGER SIEGFRIED
IPC: B65D88/12
Filed: 1994-11-02
Granted: 1998-02-23
Abstract: PCT No. PCT/DE94/01338 Sec. 371 Date Aug. 15, 1996 Sec. 102(e) Date Aug. 15, 1996 PCT Filed Nov. 2, 1994 PCT Pub. No. WO95/12536 PCT Pub. Date May 11, 1995A high-capacity container has a receiving bracket for a hook, adjustable support rollers, upper straps which form forklift pockets, wherein slide rails are located under a container floor and connected to receptacle supports, support rollers are located in corner areas below the container floor to be pivoted-in and pivoted-out to be positioned in the container and in a plane below the corners, while the forklift pocket includes upper and lower straps, and a reinforcement is provided between and in the slide rails and a frame profile in the area of the forklift pockets.
Patent DK-0744950-T3 (DK)
Inventor: IKEGAWA RURIKO
IPC: A61P9/00
Filed: 1995-02-20
Granted: 2004-10-25
Abstract: PCT No. PCT/JP95/00244 Sec. 371 Date Aug. 8, 1996 Sec. 102(e) Date Aug. 8, 1996 PCT Filed Feb. 20, 1995 PCT Pub. No. WO95/22329 PCT Pub. Date Aug. 24, 1995An agent for the prophylaxis or treatment of TXA2-mediated diseases, particularly, a TXA2 synthetase inhibitor, which comprises a pyridazinone compound of the formula (I)    <IMAGE>  (I)  wherein each symbol is as defined in the specification, or a pharmacologically acceptable salt thereof as an active ingredient. The pyridazinone compound (I) and pharmacologically acceptable salts thereof used in the present invention have prophylactic and therapeutic activities against TXA2-mediated diseases, particularly a TXA2 synthetase inhibitory action and are useful as an agent for the prophylaxis or treatment of TXA2-mediated diseases, particularly as TXA2 synthetase inhibitors.
Patent DK-0754234-T3 (DK)
Inventor: NICHOLSON DONALD W
IPC: C12N5/10
Filed: 1995-04-04
Granted: 1999-11-29
Abstract: A complementary DNA (cDNA) encoding full length form of ICErel-II is identified, sequenced and isolated. The cDNA is cloned into expression vectors for expression in recombinant hosts. The cDNA is useful to produce recombinant full length ICErel-II. The cDNA and the recombinant ICErel-II protein derived therefrom are useful in diagnostic kits, laboratory reagents and assays. The cDNA and the recombinant ICErel-II protein may be used to identify compounds that affect ICErel-II function, inflammation and cell apoptosis. ICErel-II function, inflammation and cell apoptosis may also be modulated by ICErel-II antisense or gene therapy.