baber/WOPTO huggingface dataset:
Patent CA-2670892-A1 (CA)
Title: Substituted diazepan compounds as orexin receptor antagonists
Inventor: COX CHRISTOPHER D
IPC: C07D471/04
Filed: 2007-11-30
Abstract: The present invention is directed to substituted diazepan compounds which are antagonists of orexin receptors, and which may be used in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds. These compositions may be used in the prevention or treatment of such diseases in which orexin receptors are involved.
Patent CA-2673281-A1 (CA)
Inventor: QUEAU JEAN-PIERRE
IPC: F16L59/153
Filed: 2007-12-07
Abstract: Cryogenic transfer hose for hydrocarbons comprising an inner hose, an outer hose arranged around the inner hose in a concentric manner and a spacer member bridging an annular gap between the inner and outer hoses, a fibrous insulation material forming a three dimensional matrix of fibres being comprised in the annular gap, characterised in that the outer hose comprises an elastomeric and/or a plastic material, the fibrous material being contiguous overall best a part of the length of the hoses with the inner and outer hose and forming a spacer member.
Patent CA-2675910-A1 (CA)
Inventor: JOHANSSON BENNY
IPC: A61F11/00
Filed: 2009-08-20
Abstract: Un instrument pour le traitement thérapeutique de l'acouphène est décrit, dans lequel un instrument pour le traitement de l'acouphène comprenant une matrice géométrique topographique et un support, chaque matrice géométrique topographique étant appliquée au support et comprenant a) au moins deux cercles concentriques, b) un cercle ayant au moins un cercle gravé, dans lequel ledit cercle et ledit au moins un cercle ont un point d'arc tangentiel commun; dans lequel pour les deux a) et b) ci-dessus, le cercle le plus intérieur est ouvert ou fermé, le diamètre du cercle le plus extérieur est d'au plus 130 mm, et le diamètre du cercle le plus intérieur est d'au plus 3 mm, et dans lequel le rapport entre le diamètre du cercle le plus extérieur et le diamètre du cercle suivant compté vers le centre commun des cercles est d'au moins 1.3; c) un ensemble de cercles identiques disposés avec la base du motif de la fleur de vie montrée à la figure 2, ou des variantes asymétriques de a) à c) qui ont la capacité de synchroniser l'eau selon le test de synchronisation tel que défini dans l'exemple 1, ainsi qu'une méthode de traitement thérapeutique de l'acouphène, dans laquelle au moins un instrument tel que défini ci-dessus est appliqué sur le corps du patient acouphène, de préférence sur la peau de la moitié supérieure du corps, plus préférablement de la tête, et idéalement à proximité de l'oreille touchée, et est soumis à une lumière d'une longueur d'onde de 360 à 4000 nm, de préférence la lumière du jour.
Patent CA-2676170-A1 (CA)
Title: Activation specifique d'un lymphocyte t regulateur et son utilisation pour le traitement de l'asthme, d'une maladie allergique, d'une maladie auto-immune, d'un rejet de greffe et pour une induction de tolerance
Inventor: JONULEIT HELMUT
IPC: G01N33/50
Filed: 2008-01-30
Abstract: La présente invention porte sur l'activation spécifique d'un lymphocyte T régulateur par l'intermédiaire d'un épitope CD4 spécifique et sur ses utilisations, par exemple pour le traitement d'une maladie auto-immune ou d'une allergie ou de l'asthme ou du rejet de greffe ou d'une induction de tolérance.
Patent CA-2678429-A1 (CA)
Title: Tv-centric system
Inventor: HIRONAKA TAKASHI
IPC: H04N7/16
Filed: 2008-02-13
Abstract: A method for abstracting a TV hardware component (26/28/30) to a service class to facilitate providing services through a TV.
Patent CA-2683480-A1 (CA)
Inventor: PONA ZBIGNIEW
IPC: A61C13/38
Filed: 2008-03-20
Abstract: A vibrating dental tool (10) for the removal of crowns and bridges, the d ental tool (10) having a pair of opposing jaw members (12: 12a and 12 b). A biasing mechanism (18) connected to at least one of the jaw members (12) bia ses the jaw members (12) toward a proximate rest position. Actuator (30) is connected to at least one jaw member (12) for separating the jaw members (12 ). An ultrasonic vibrator is connected to the jaw members (12) for vibrating them Securing means connect the pair of opposing jaw members.
Patent CA-2686350-A1 (CA)
Inventor: HORNSBY JAMES RUSSELL
IPC: A63H33/00
Filed: 2009-11-25
Abstract: The present invention is directed to an interactive intelligent toy that provides the appearance and experience of a person, animal, vehicle, or other character moving in, and/or interacting with, its environment or habitat on its own. In one embodiment, a motive component simulating the appearance of a person, animal, vehicle or other character comprises a drive mechanism to move the motive component, a control mechanism and a power source. The control mechanism is programmed to monitor and detect user and event inputs, and to detect and decode embedded codes in a pathway component and perform predetermined actions or generate predetermined sounds in response to the inputs and codes. In another embodiment, the motive component engages with a coupling component and supplies the drive mechanism and power source for moving both the motive component and the coupling component. In yet another embodiment, the motive component is adapted to perform certain actions upon contact with, or becoming in proximity to, an auxiliary component. The invention therefore provides a simulated character that appears to have a mind of its own in operating within a certain environment.  Given that the intelligent element is able to supply the means (drive mechanism, control mechanism and power source) to enable other elements to perform actions, the cost of the toy can be minimized while providing a large variety of different activities and the ability to expand to new environments and activities.
Patent CA-2686428-A1 (CA)
Inventor: HOERTNAGL ANDREAS
IPC: A63B29/00
Filed: 2009-11-23
Abstract: A karabiner having at least one hoop (1) and at least one closing part (2) and at least one insertion opening (3) of the hoop (1), which can be closed by the closing part (2) in its closed position, with the closing part (2) being mounted pivotally via a closing part pivoting axle (4) to the loop (1) between the closed position and a maximally opened position and at least one blocking element (5) being pivotally mounted at or in the closing part (2) via a blocking element - pivot axle (6), with the blocking element. (5), at least in a closed position of the closing part (2), blocking the closing part (2) in its closed position from pivoting in the direction towards its maximally opened position and in at least one released position allows the closing part (2) to pivot in the direction towards its maximally opened position.  The blocking element (5) is pivoted around the blocking element - pivot axle (6) for pivoting it out of the blocking position in the direction towards the released position in the same rotary direction (7) around the blocking element - pivot axle (6) as the closing part (2) for pivoting the closing part (2) out of the closed position in the direction towards its maximally opened position around the closing part -pivot axle (4).
Patent CA-2688146-A1 (CA)
Inventor: OLSON KATIE
IPC: C12P21/08
Filed: 2008-05-21
Abstract: The present invention is directed to antibodies and fragments thereof having binding specificity for IL-6. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL and CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-IL-6 antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making said anti-IL-6 antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-IL-6 antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with IL-6. These antibodies may bind at least one of soluble IL-6, cell surface expressed IL-6, IL-6/IL-6R and/or prevent the association of IL-6 and IL-6R, the association of IL-6/IL-6R and gp130 and or the formation of IL-6/IL-6R/gp130 multimers and thereby inhibit a biological effect associated with any of the foregoing.
Patent CA-2688663-A1 (CA)
Title: Procede pour decouper un support d'impression plan
Inventor: DUBESSET DIDIER
IPC: B26F1/38
Filed: 2008-06-26
Abstract: La présente invention concerne un procédé pour découper un support d'impr ession plan. Elle appartient au domaine de la découpe d'un support d'impress ion plan, tel qu'une feuille ou une plaque, autour d'au moins un motif préal ablement imprimé sur ce support d'impression. Le procédé consiste : - a déte cter (155) au moins une séquence de points caractéristiques de la géométrie d'un contour de découpe sur la base des marques de découpe; - a affecter (15 6) chaque point caractéristique détecté a au moins un contour de découpe; - a rechercher des éléments caractéristiques (bord de contour, coin de contour ) dudit contour sur la base desdits points caractéristiques, puis - a tradui re (164) le contour de découpe en informations vectorielles pour générer un programme de découpe d'au moins un contour de découpe.
Patent CA-2691107-A1 (CA)
Inventor: UENO RYUJI
IPC: A61P25/28
Filed: 2008-07-03
Abstract: Provided is a pharmaceutical combina-tion of a NSAID and a prostaglandin compound of for-mula (I). The combination of the invention is useful for the indications for NSAID use such as pain, Alzheimer disease and cancer.
Patent CA-2692011-A1 (CA)
Inventor: SCHLUETER WERNER
IPC: E04C2/20
Filed: 2010-02-05
Abstract: A building board (10; 60) as a carrier for a surface cladding of tiles, a plaster or a thin-layer trowel mortar having a moisture-resistant foam core layer (24; 74) which is provided on both sides with a paper or plastic film web (26; 76) on which a fibre material web (30; 80) made of nonwoven fabric or a knitted or machine-knitted fabric defining the outer side of the building board is disposed, the building board (10; 60) being provided with at least one groove (32a, b; 82a, b, c...) which extends from a face side of the building board (18; 68) to the opposing face side of the building board (22; 72), and largely penetrates the foam core layer (24; 74) from an outer side (12; 62) of the building board (10; 60).
Patent CA-2693561-A1 (CA)
Inventor: TRIMMER ANDREW LEE
IPC: B23H5/02
Filed: 2008-06-05
Abstract: An apparatus and method for hybrid machining a workpiece is disclosed. The workpiece (50) is powered as an anode, a cutter (14) is powered as a cathode and a cutting fluid or coolant is circulated therebetween. The cutter is made of a conductive material and a non-conductive abrasive material. The hybrid machine (10) performs a roughing pass machining operation in.which material is removed from the workpiece at a relatively high rate using a high-speed electro-erosion (HSEE) process. Then, the hybrid machine performs a finish pass machining operation in which material is removed from the workpiece using precision electro-grinding (PEG) process at a different differential electrical potential and/or flushing rate than the roughing pass machining operation to provide a smooth finish without thermal effects on the workpiece.
Patent CA-2693725-A1 (CA)
Inventor: HOULE JACQUES
IPC: F23D99/00
Filed: 2010-02-19
Abstract: A fireplace unit comprises a housing in which a liquid fuel is to be combusted, having at least one aperture for air flow; a front plate; and a burner for holding the liquid fuel having an adjusting means for adjusting intensity of flame. A  drawer is provided to hold the burner.     A closing means is provided to cover the burner such that the flame is extinguished when the closing means is closed. The adjusting means is configured to close when the drawer is pulled out. A security means is further provided to refrain the drawer from being pulled out when the closing means is open. The drawer further includes a reservoir for holding over-filled or leaked liquid fuel.
Patent CA-2696232-A1 (CA)
Inventor: NAN FAJUN
IPC: A61K31/426
Filed: 2008-02-26
Abstract: PTP1B inhibitors with the following structure (formula I). Experiments indicate that these inhibitors can effectively inhibit the activity of protein tyrosine phosphatase 1B (PTP1B). They can be used as insulin sensitisers. They can be used to prevent, delay or treat diseases which are related to insulin antagonism mediated by PTP1B, especially diabetes type II  and obesity. The invention also provides methods for preparing these inhibitors.     (see formula I)
Patent CA-2696895-A1 (CA)
Title: Materiau composite de faible densite
Inventor: ORANGE GILLES
IPC: C08K3/34
Filed: 2008-07-04
Abstract: La présente invention concerne un matériau composite de faible densité et de haute ténacité à base de polymère thermoplastique, en particulier présentant des performances mécaniques élevées à haute température, notamment à la compression. L'invention concerne aussi un procédé de préparation dudit matériau, ainsi que ses utilisations, notamment dans le domaine de la récupération de boues, liquides et gaz présents dans des réservoirs souterrains, et en particulier dans le domaine de l'extraction d'hydrocarbures, tels que le pétrole brut ou le gaz naturel.
Patent CA-2700323-A1 (CA)
Title: Spraying device and method of using same
Inventor: BUTLER MARTIN
IPC: B65D83/16
Filed: 2008-09-22
Abstract: A spraying device (10) is described, the device comprising a housing (12) adapted to receive a refill (16) of fluid therein and having an aperture (14) suitable for permitting, in use, the spraying of a fluid therethrough, the device further comprising actuation means (24) configured for periodic actuation of the refill, wherein the device is provided with detection means (26) configured to distinguish between at least one area of lower reflectance and at least one area of relatively higher reflectance on a spray head of said refill. Methods of operation of such a spraying device are also described.
Patent CA-2702828-A1 (CA)
Inventor: HEDMAN THOMAS P
IPC: A61F13/00
Filed: 2008-07-06
Abstract: A method of treatment of native, non-denatured tissue to increase resistance to tearing, fissuring, rupturing, and/or delamination, comprising the step of: contacting at least a portion of the tissue with an effective amount of a reagent that increases crosslinks in the tissue.
Patent CA-2703129-A1 (CA)
Title: Minimially invasive repair of a valve leaflet in a beating heart
Inventor: ZENTGRAF JOHN
IPC: A61B17/34
Filed: 2008-10-20
Abstract: A device for performing minimially invasive repair of mitral valve leaflets in a beating heart through the delivery and implantation of artifical chordae tendinae includes a handle for positioning the device into a chest cavity of the patient, a capture assembly adapted to capture a valve leaflet between distal an proximal tip portions, a needle adapted to penetrate the valve leaflet, and a capture confirmation system for verifying capture of the valve leaflet between the distal and proximal tip potions.
Patent CA-2706071-A1 (CA)
Inventor: PUGIN BENOIT
IPC: B01J31/12
Filed: 2008-11-14
Abstract: Compounds of the formula (I), in the form of mixtures comprising predominantly one diastereomer or in the form of pure diastereomers, Z1-Q-P*R0R1 (I) in which Z1 is a C-bonded, secondary phosphine group -P(R)2; in which R is in each case independently hydrocarbon radicals or heterohydrocarbon radicals, or Z1 is the -P*R0R1 group; Q is a bivalent, achiral, aromatic base skeleton, a bivalent, achiral ferrocene base skeleton, an optionally substituted bivalent cycloalkane or heterocycloalkane skeleton, or a C1-C4-alkylene skeleton, and in which base skeletons a secondary phosphine group Z1 is bonded directly to a carbon atom, or, in the case of cyclic base skeletons, directly to a carbon atom or via a C1-C4-alkylene group, and in which base skeletons a P-chiral group -P*R0R1 is bonded directly to a carbon atom, or, in the case of cyclic base skeletons, directly to a carbon atom or via a C1-C4-alkylene group to a carbon atom such that the phosphorus atoms are linked via 1 to 7 atoms of a carbon chain optionally interrupted by heteroatoms from the group of O, S, N, Fe or Si; P* is a chiral phosphorus atom; R0 is methyl or hydroxyl, and R0 is methyl when Z1 is the -P*R0R1 group; and R1 is a C-bonded optically enriched or optically pure chiral, mono- or polycyclic, nonaromatic hydrocarbon or heterohydrocarbon radical which has 3 to 12 ring atoms and 1 to 4 rings and which has a stereogenic carbon atom at least in the a position to the P-C bond; Metal complexes of these ligands are homogeneous catalysts for asymmetric addition reactions, particularly hydrogenations.
Patent CA-2706467-A1 (CA)
Inventor: PERONA ABELLON ROSARIO
IPC: A61K38/45
Filed: 2008-11-21
Abstract: This invention describes the use of an inductor or activator compound GSE24.2 for producing a medicament or pharmaceutical composition for treating a preferably human illness or pathological situation caused by a senescence process. Said pharmaceutical composition can be useful for a treatment of tissue regeneration, for example of epithelial tissues or haematopoietic cells, and also for the immortalisation of eukaryote cells for use of same in biotechnological research or processes.
Patent CA-2707324-A1 (CA)
Inventor: LAPIERRE ALEXANDRE
IPC: F22B37/10
Filed: 2010-06-11
Abstract: The present document describes a boiler for heating a cold fluid with a hot fluid. The boiler comprises: a lower drum; an upper drum; a plurality of right tubes for conveying the cold fluid, each of the right tubes fluidly connecting the lower drum and the upper drum, the right tubes forming a right wall, each of the right tubes comprising at least one left inwardly extending portion extending toward a left wall; and a plurality of left tubes for conveying the cold fluid, each of the left tubes fluidly connecting the lower drum and the upper drum, the left tubes forming the left wall facing the right wall, each of the left tubes comprising at least one right inwardly extending portion, each extending toward the right wall; wherein the at least one right inwardly extending portion is contiguous to and staggered with the at least one left inwardly extending portion, forming at least two passages between the right wall and the left wall, each one of the at least two passages having first and second ends and being substantially isolated from each other between each of its respective first and second ends; in use, the hot fluid circulates in the at least two passages and heats the right tubes and the left tubes, thereby heating the cold fluid.
Patent CA-2709404-A1 (CA)
Inventor: MCGONIGLE BRIAN
IPC: C12N15/82
Filed: 2008-12-17
Abstract: Isolated nucleic acid fragments comprising precursor miRNAs, and artificial miRNAs and their use in down-regulating gene expression are described.
Patent CA-2712506-A1 (CA)
Inventor: SKELTON AMANDA
IPC: A01N25/12
Filed: 2009-01-19
Abstract: A lure for house dust mite control, by drawing mites from deep inside the furniture and mattresses, where upon they would become exposed to a naturally produced acaricide and subsequently vacuumed, is taught. The composition comprises neryl formate, and may also comprise limonene, wherein the limonene is substantially in the form of the R-(+)-limonene enantiomer.
Patent CA-2717465-A1 (CA)
Inventor: WATERHOUSE GEOFFREY S
IPC: A47K7/02
Filed: 2010-10-07
Abstract: The device is a portable hanging soap container, skin washing, and bubble bath bubble enhancing device made from fabric material. It can be used to hold soap, hang your soap, carry or transport your soap, wash skin, and as a bubble bath bubble enhancer. It has one opening that allows for insertion of soap, which has a looped drawstring sewn into it with two cord locks attached to the drawstring; it has another string that is looped and attaches to the alternating side and top or bottom of the container from the drawstring with the cord locks attached.
Patent CA-2721275-A1 (CA)
Title: Apparatus, and associated method, for facilitating radio control system operation with an ics-capable wireless device
Inventor: ALLEN ANDREW
IPC: H04W76/02
Filed: 2009-04-14
Abstract: An apparatus, and an associated method, for facilitating communication operations with a wireless device that is ICS or DTM capable. A message generator is provided, configured to generate a network-terminated message, the network-terminated message including a media feature tag that identifies support of ICS. When transmitted to a network node, the message is detected. And, a wireless-device-terminated message that provides for mapping of a SIP URI into a calling name presentation.
Patent CA-2724136-A1 (CA)
Inventor: WATZKE DONALD EDWARD JR
IPC: H02H3/04
Filed: 2010-12-07
Abstract: A method and apparatus for controlling a controlled device. The apparatus may include a plurality of switching devices connected in series.
Patent CA-2725873-A1 (CA)
Inventor: KIM KYUNG JIN
IPC: C07K16/22
Filed: 2009-05-28
Abstract: The present invention is directed toward a neutralizing monoclonal antibody to basic fibroblast growth factor, a pharmaceutical composition comprising same, and methods of treatment comprising administering such a pharmaceutical composition to a patient.
Patent CA-2726881-A1 (CA)
Title: Light emitting assembly with independent elongated sections
Inventor: HOCHSTEIN PETER A
IPC: F21V29/00
Filed: 2008-06-05
Abstract: A light emitting assembly (10) is fabricated by forming a continuous strip of aluminum heat sink having a pair of fins (32) aligned with the side edges (20) and cutting the continuous strip into a plurality of elongated sections (18). The elongated sections (18) are disposed in spaced and generally parallel relationship to one another and separated by an elongated slot (26) so that adjacent elongated sections (18) are independent of one another. A  plurality of light emitting diodes (24) are disposed on the mounting surface (14) of each elongated section (18). Bridges (28) constructed of a material different from the material of the heat sink interconnect the elongated sections (18). An independent cover (52) is adhesively secured to the mounting surface (14) around the light emitting diodes (24) on each elongated section (18). A housing (56) spaced from the fins (32) is disposed over the assembly (10).
Patent CA-2727837-A1 (CA)
Inventor: LAWSON JOHN A
IPC: C07D489/04
Filed: 2009-05-08
Abstract: The disclosure describes morphinan compounds and methods for their synthesis.  Preferred methods according to the disclosure allow for large-scale preparation of diastereomerically enriched morphinans. Preferred methods according to the disclosure may also allow for the preparation of diastereomerically enriched morphinans using less time, and/or using fewer reaction steps, and/or providing better yield than previously used methods for preparing morphinans. The methods disclosed herein find utility in synthetic organic chemistry as well as medicinal chemistry.
Patent CA-2728005-A1 (CA)
Inventor: SCHLEGEL THOMAS
IPC: A45C3/00
Filed: 2011-01-14
Abstract: A storage bag system for a wagon includes a collapsible storage bag that is movable between an expanded configuration and a collapsed configuration. The storage bag system also includes a connector for attaching the collapsible storage bag to a sidewall of the wagon. As a result, the invention provides additional hauling and storage capacity for a wagon via a collapsible storage bag that may be moved to a collapsed configuration.