baber/WOPTO huggingface dataset:
Patent EC-SP034664-A (EC)
Title: Derivados de tetrahidropiridina su preparacion y su uso como inhibidores de la proliferacion celular
Inventor: GROSSMANN ADELBERT
IPC: A61P35/00
Filed: 2003-06-22
Abstract: Un compuesto de la fórmula: (Gráfico) (a) denota un grupo fenilo que puede estar no sustituido o sustituido con 1, 2 o 3 sustituyentes independientemente seleccionados entre un átomo de halógeno, un grupo alquilo (C1-4), trifluorometilo, hidroxi-, alcoxi (1-4C)-, benciloxi-alquilendioxi (C1-3), nitro-, amino, alquilamino (C1-4)-, dialquil (C1-4) -amino-, alcanoil (C1-4)-amino-o un grupo fenilo, que puede estar no sustituido o sustituido con 1, 2 o 3 sustituyentes independientemente seleccionados entre un átomo de cloro, un grupo alquilo (C1-4), trifluorometil, hidroxi-, alcoxi (1-4C)-,alquilendioxi(C1-3)-, nitro, amino-, alquilamino (C1-4)-, dialquil (C1-4)-amino-y un grupo alcanoilamino (c1-4), o (b) denota un grupo indolilo que puede estar no sustituido o sustituido con 1, 2, o 3 sustituyentes independientemente seleccionados entre un átomo de halógeno, un grupo alquilo (C1-4), trifluorometilo, hidroxi-, alcoxi (1-4C)-, benciloxi-alquilendioxi (C1-3)-, nitro-, amino, alquilamino (C1-4)-, dilaquil (C1-4)-amino-, o un grupo alcanoilamino (C1-4)-, R1 y R2 son iguales o diferentes entre se y representan un átomo de hidrógeno, un grupo alquilo (C1-4), un grupo trifluorometilo o un grupo arilo, X es un grupo alquileno de cadena recta que comprende 5, 6 o 7 átomos de carbono, donde un grupo CH2 puede ser reemplazado por un átomo de oxígeno o azufre, donde 2 átomos de carbono forman un doble enlaceC=C, y que está no sustituido o sustituido con uno o dos sustituyentes seleccionados entre alquilo (c1-4) y átomos de halógeno, sus enantiómeros, distereoisómeros, racematos y mezclas de los mismos, así como sus sales farmacéuticamente aceptables.
Patent EC-SP045039-A (EC)
Title: Composiciones de disgregación intraoral organolepticamente aceptables
IPC: A61K47/00
Filed: 2004-03-26
Abstract: La presente invención se refiere a composiciones farmacéuticas de disgregación intraoral que contienen un fármaco organolépticamente inaceptable como ingrediente activo, y a procesos para preparar dichas composiciones.
Patent EC-SP077262-A (EC)
Title: Composicion antihistaminica
Inventor: LULLA AMAR
IPC: A61K31/4545
Filed: 2007-02-16
Abstract: Una composición farmacéutica estable que consiste de desloratadina ó una sal, solvato, derivado, polimorfo, hidrato ó enantiómero de la misma, y un portador que consiste de por lo menos un poliol. Las composiciones preferidas consisten de, además de la desloratadina, desde 50 hasta 80% de poliol, desde 5 hasta 15% de agente desintegrante, y desde 0,01 hasta 0,5% de un antioxidante y/ó un agente de quelación, todos por peso de la composición.También se provee para el uso de un poliol para estabilizar una composición farmacéutica que consiste de desloratadina.Un proceso para hacer una composición farmacéuticamente estable que consiste de desloratadina y uno ó más polioles, opcionalmente junto con otros excipientes farmacéuticamente aceptables, que consiste en combinar los ingredientes y formularlos para formar dicha composición.
Patent EC-SP088670-A (EC)
Title: Sistema de administracion de plaguicidas
Inventor: KABANOV ALEXANDER V
IPC: A01N25/00
Filed: 2008-08-08
Abstract: Se revela un sistema de administración de plaguicidas mejorado. El sistema está basado en una micromezcla que comprende (a) un compuesto anfifílico que contiene por lo menos un grupo hidrófilo y por lo menos un grupo hidrófobo y (b) un plaguicida. También se revelan composiciones basadas en la micromezcla y métodos para usar las composiciones para controlar plagas.
Patent EC-SP099637-A (EC)
Title: Anticuerpos contra el erbb3 y los usos de los mismos
Inventor: SCHOEBERL BIRGIT
IPC: A61K33/243
Filed: 2009-09-15
Abstract: La presente invención proporciona una clase novedosa de anticuerpos monoclonales que enlazan a receptores ErbB3 y que inhiben varias funciones ErbB3. Por ejemplo, los anticuerpos descritos en la presente son capaces de enlazarse a ErbB3 y de inhibir la fosforilación del receptor mediada por un ligante similar al EGF
Patent EC-SP099776-A (EC)
Title: Moduladores de la gamma secretasa
Inventor: PALANI ANANDAN
IPC: A61K31/4166
Filed: 2009-12-01
Abstract: En sus muchas realizaciones, la presente invención proporciona una novedosa clase de compuestos heterocíclicos de la fórmula: Fórmula Icomo moduladores de la gamma secretasa, métodos para la preparación de dichos compuestos, composiciones farmacéuticas que contienen uno o más de dichos compuestos, métodos para la preparación de formulaciones farmacéuticas que comprenden uno o más de dichos compuestos, y métodos de tratamiento, prevención, inhibición, o alivio de una o más de varias enfermedades asociadas con la sistema nervioso central usando dichos compuestos o composiciones farmacéuticas.
Patent EC-SP992984-A (EC)
Title: Derivados de isotiazol utiles como agentes anticancerosos
Inventor: NOE MARK CARL
IPC: A61K31/42
Filed: 1999-06-04
Abstract: La presente invención se refiere a compuestos de fórmula I, (gráfico), y a sales farmacéuticamente aceptables, profármacos y solvatos de los mismos, en los que X1, R1, R2 y R3 son como se han definido en la presente. La invención también se refiere a composiciones farmacéuticas que contienen los compuestos anteriores y a procedimientos de tratamiento de trastornos hiperproliferativos en mamíferos mediante la administarción de los compuestos anteriores.
Patent FI-20002396-A (FI)
Inventor: IKONEN RIKU
IPC: H03F1/02
Filed: 2000-10-31
Abstract: The invention relates to a linearization method and an amplifier arrangement for linearizing an amplifier ( 50 ) amplifying an RF signal with a variable envelope. The amplifier arrangement comprises a sampling device ( 20 ) for sampling an RF signal to be amplified. The amplifier arrangement further comprises a control device ( 30 ) arranged to generate, using samples, an output signal changing its value according to the envelope shape of the RF signal to be amplified. The amplifier arrangement further comprises an adjusting device ( 40 ) arranged to adjust, using the output signal, the bias current of the amplifier such that the magnitude of the output signal and the magnitude of the bias current change in the same direction.
Patent FR-1143342-A (FR)
Inventor: HANLET JACQUES-MARIE-NOEL
IPC: H01L21/00
Filed: 1955-12-30
Granted: 1957-09-30
Abstract: 837,015. Contacting fluids with liquids. BERRY, J. L. Dec. 24, 1956 [Dec. 30, 1955], No. 39213/56. Class 55 (2). Apparatus for contacting fluid and liquid phases comprises within a column a number of superimposed chambers having two open opposing vertical sides through which the chambers intercommunicate in groups through passageways formed between the chambers and the walls of the column, the number of groups of chambers corresponding to the number of individual fluid-liquid contacting paths, each of which has an inlet and an outlet for both a fluid constituting the lighter phase and a liquid constituting the denser phase, plates fixed to the inner wall of the column to extend alternately into the successive chambers of the same fluid-liquid path through one of the open sides of one of the chambers, and then into the opposite open side of the succeeding chamber, each plate forming at its fixed end a liquidcollecting trough and at its free end a liquid discharging sill, each chamber having at its base a depending wall which extends into the liquid collecting trough of the next lower chamber to form an hydraulic seal with liquid collecting in the trough when the apparatus is in use. When there are n fluid-liquid contacting paths, n being an integer equal to at least 2, the successive chambers of each contacting path are separated from each other by n - 1 chambers of the remainder of the contacting paths and each chamber is displaced from the preceding chamber by an angular displacement of #/n radians. The apparatus shown has two fluid-liquid contacting paths, chambers A 1 , B 1 , C 1  . . . constituting one path and chambers A 2 , B 2 , C 2  . . . constituting the other, the paths having a common fluid inlet and outlet and a common liquid inlet and outlet and successive chambers being displaced angularly by 90 degrees. In a modification the base and top of the chambers are dished to form additional liquid collecting troughs. Specification 755,548 is referred to.
Patent FR-1605013-A (FR)
Title: Catalyst for hydrazine decompsn - contg iridium in alumina
IPC: B01J23/46
Filed: 1968-05-22
Granted: 1972-08-28
Abstract: Catalyst is made by (a) preparing Al(OH)3 as carrier, (b) adding sufficient hydrochloridic acid to give 27% Ir in Al2O3 in the final body, boiling with stirring to form a gel, drying (3) heating to 350 degrees C. in N2 to remove water, (4) reducing in N2 at 350 degrees C. to obtain metallic Ir and (5) impregnating with nitric acid then agglomerating and finally heat treating in H2 at 350 degrees C.
Patent GB-1054452-A (GB)
IPC: G01F11/00
Abstract: 1,054,452. Delivering measured quantities of liquid. M. K. AICHELE. March 3, 1964, No. 7813/66. Divided out of 1,054.451. Heading B8N. A device for dispensing measured quantities of a mouldable plastic material such as used in the bottle cap making machine disclosed in Specification 1,054,451 comprises a body member 39 having inlet and outlet passages 40, 50, a measuring plunger 48 adapted to deliver a measured quantity of material from the inlet to the outlet passage and into the path of a delivery plunger 53, means 51 to close communication between the inlet and outlet passages when the measuring plunger is retracted and means 56, 57, 58 associated with the delivery plunger for discharging compressed air for detaching plastic material from the delivery plunger. The plungers 48, 53 are reciprocated by means of a lever 44, 45, 46 oscillated via a gear-driven crank. In operation, with the measuring plunger in the position shown plastic material is fed by a screw through the inlet passage 40 to fill it. When the measuring plunger is lowered it forces a measured quantity into the outlet passage 50 so that a corresponding amount extends from the end of the outlet passage above a bottle cap L. When the crank again rotates the lever raises the measuring plunger so as to allow more material to enter the inlet and lowers the delivery plunger which cuts off the extruded measured quantity of material and carries it towards the cap. As the delivery plunger reaches the downward limit of its stroke, an air vent passage 58 in the plunger is brought into communication with a cornpressed-air supply passage 56 so that an air jet separates the measured quantity from the plunger. In a modification, Fig. 4 (not shown), the delivery plunger is formed from an inner slide member 148 connected to the lever 44 and arranged for limited sliding movement in an outer slide member 134. In operation, when a measured quantity has been extruded into a member 178, the inner and outer slide are moved together downwardly so that the measured quantity is forced through a nozzle 184. Upon the return stroke, a needle valve 162 on the inner slide is withdrawn from an orifice in the lower end of the outer slide so as to permit compressed air to flow through the orifice and force the material into a cap.
Patent GB-1089566-A (GB)
IPC: H04W76/02
Abstract: 1,089,566. Automatic exchange systems WESTERN ELECTRIC CO. Inc. May 11, 1965 [May 18, 1964], No. 19771/65. Heading H4K. In a system wherein a number of mobile stations are catered for by the provision of a smaller number of radio channels by which they may be linked to the exchange or base station, provision is made also for " roaming " mobile stations which are normally based in other areas. Exchanges having similar designations exist for example in London and Liverpool. To avoid confusion therefore, when a mobile station is called the number sender associated with the terminal equipment inserts the area designation before the numerical digits, and an operator calling a " roaming " station would first dial the area digits. Similarly, a calling mobile station is arranged to send its area designation before its directory number. If the area designation corresponds with that of the exchange where it is received the call is set up by dialling in the normal manner, but if it does not correspond the call is directed to an operator's switchboard. In the system described 8 radio channels are provided for 480 mobile stations, each of which has an individual line circuit at the exchange.
Patent GB-1225094-A (GB)
IPC: B29C61/00
Filed: 1969-02-12
Abstract: 1,225,094. Shrinkable polyurethane films. KABEL - UND METALLWERKE GUTEHOFFNUNGSHUTTE A.G. 12 Feb., 1969 [17 Feb., 1968], No. 7603/69. Heading B5B. A shrunk-on envelope is made by using as the envelope forming material a polyurethane which has not been cross-linked by irradiation at any stage in its production. A hollow body comprising the said polyurethane may be prepared by heating it to a temperature between 50‹ and 100‹ C., preferably to about 80‹ C., stretching at that temperature if not stretched before heating, cooling in the stretched condition and then shrinking to form the shrunk-on envelope by heating above 100‹ C., preferably about 170‹ C.
Patent GB-1225596-A (GB)
IPC: B22F9/10
Filed: 1969-11-04
Abstract: 1,225,596. Granulating metals. W. SCHUSTER and H. WINTER. Nov. 4, 1969, No.54026/69. Heading C7X. Method and apparatus of granulating metal comprises immersing one end of a tube below the surface of a molten metal bath, the other end of the tube above the bath forming a perforated hollow cylinder with a closed end and rotating the tube so that the metal is ejected from the perforations. The ratio of internal diameter d 1  to outer diameter d 2  of the cylinder i.e. d 1 /d 2  > 0À33 and d 3  internal diameter of tube is< d 1 . Ratio d1/d2- is preferably > 0À66 and d 3  preferably between 0À2 and 0À5 d 1 . Fig. 1 shows the perforated cylinder a) connected to the tube c) immersed in melt, by a conical section b) to form sprayer 23 which is rotated at 600-900 rpm to produce granules 0À1- 3mm. and at 7000-18000 rpm for granules smaller than 0À3mm. Argon is fed into the cylinder a) via shaft 1 and the metal is ejected from perforations 6 into an argon atmosphere or a vacuum. A reservoir of molten metal may be connected to the molten metal bath Fig. 2 (not shown) and in a further embodiment Figs. 3 and 4 (not shown) a stream of argon may be introduced above the melt surface to help force the melt into the perforated cylinder. The perforated cylinder may be a net or sieve e.g. op N6 alloy for Cu melts, stainless steel for Al melts or Ni for P6 melts. Alternatively the tube and cylinder may be iron or steel, graphite or ceramic with drilled perforations. Metals sprayed may be alkali metals, Al, Mg, Fe, Cu, P6, Sn.
Patent GB-1228654-A (GB)
IPC: G21C3/62
Filed: 1968-06-28
Abstract: 1,228,654. Sub-stoichiometric oxides. SADEM SOC. ANON. DES ENTREPRISES MINIERES. 28 June, 1968 [3 July, 1967], No. 30961/68. Heading C1A. [Also in Division G6] Nuclear fuel comprising sub-stoichiometric uranium, thorium, plutonium, or mixed oxide is stabilized by the addition of a small amount of chromium, molybdenum, tungsten, or rhenium. The sub-stoichiometric oxide may be formed by heating the dioxide with metallic nuclear fuel or in a reducing atmosphere. The product has an increased heat conductivity, a higher nuclear density, and a higher burn-up, and is compatible with cladding at reactor operating temperatures.
Patent GB-1230236-A (GB)
IPC: B01D25/19
Filed: 1969-09-04
Abstract: 1,230,236. Filter press. RITTERSHAUS & BLECHER G.m.b.H. 4 Sept., 1969 [23 Oct., 1968], No. 43910/69. Heading B1D A stack of press plates 10 is pulled against a fixed head 1 by a member 5, pivotally suspended and movable along rail 3 by virtue of its connection by four pull rods 6, 7, (8, 9) to a similar member 4, on whose central area piston 12, extending from a hydraulic cylinder 11 mounted on the left-hand side of head 1, acts to move members 4, 5 to the left, and the connections between members 4, 5 and rods 6, 7, (8, 9) and between piston 12 and member 4 all permit lateral pivoting of members 4, 5 to avoid straining if the plate stack is thicker on one side or corner than elsewhere. Fig. 3 (not shown) illustrates the convex surface (17) of member 4 on which the flat end of piston 12 bears when advancing, sleeve (18), flange (19) and resilient ring (21) enabling piston 12 to pull member 4 rightwards when retracting. Fig. 4 (not shown) illustrates the part-spherical bearing surfaces on a nut (24), on the end of a rod, and on a surrounding collar on member 5.
Patent GB-1232188-A (GB)
IPC: G01K5/32
Filed: 1970-02-05
Abstract: 1,232,188. Measuring temperature. BRITISH OXYGEN CO. Ltd. Feb. 5, 1970, No. 5671/70. Addition to 1, 162, 033, Heading G1D. Temperature sensing apparatus particularly for use in indicating whether or not a pump for pumping low temperature liquefied gases is full of liquid before starting up to avoid damage to the pump, comprises a differential pressure gauge 36 one side of which is connected by a conduit 34 to a bulb 32 located in a flange 6 in the inlet pipe 8 to the pump from a storage tank for the liquefied gas, the bulb 32 containing a fluid the same as that in the pipe 8, the other side of the gauge 36 being connected by a conduit 38 to the intenar of the pipe 8 to sense the pressure therein. In operation when liquefied gas is first admitted to the pipe 8 and pump at ambient temperature, the pressure in the bulb 32 will be greater than that in the pipe 8. As the pipe 8 becomes cooled by the liquefied gas, the gas will condense in the bulb 32 thus lowering the pressure therein below that in the pipe 8. A steady state is reached with the pipe full of liquefied gas by calibration of the gauge 36 this can be indicated on the gauge to slow when the pump may safely be started.
Patent GB-1232835-A (GB)
Inventor: TRAVIS LAWRENCE R
IPC: H05K3/06
Filed: 1968-06-24
Abstract: 1,232,835. Printed circuits. ELECTRO CONNECTIVE SYSTEMS Inc. 24 June, 1968 [29 June, 1967], No. 29967/68. Heading H1R. In a method of producing a printed circuit by the selective etching of conductive foil bonded to an insulating support the etching is performed in two steps so as to form rounded corners on the printed circuit pattern. A copper foil bonded to a backing of synthetic resin is coated with an etchant resistant material on portions which are to form the completed circuit pattern by printing, mechanical, photographic or irradiation techniques. The coated foil is then subjected to an etch solution which attacks the bare portions of the metal, the etching process being terminated when 90% of the unmasked foil has been removed. After removal of the etchant resistant material from the partially relieved circuit pattern the foil is subjected to a second etch which removes the remainder of the foil between the areas of the circuit pattern and rounds the sharp uppermost corners of the pattern formed after the first etch thereby making the final printed circuitry more satisfactory for encapsulation. The sides of the partially relieved circuit pattern may be protected during the second etch.
Patent GB-1234408-A (GB)
IPC: A61K/
Filed: 1968-08-01
Abstract: 1,234,408. Treating hair. L'OREAL. 1 Aug., 1968 [2 Aug., 1967], No. 36788/68. Heading D1P. [Also in Division C2] Living human hair is treated with a composition comprising at least one compound having at least two N atoms, one of which is part of a group which is quaternisable and another is part of the radical wherein R is H or C 1-6  alkyl, hydroxymethyl or alkoxymethyl and R' is H or C 1-6  alkyl, the radical being bonded to the C atom of a -NH-CO-, -NH-CS-, -CO-, or -O-CO- group, or an acid addition or quaternary salt thereof, and, if the composition does not contain one, an acid polymerisation catalyst, and drying the hair with the application of heat. The composition preferably contains 1-10% by weight, most advantageously 2-4% of the active compound and may also contain a dye, perfume, smelling agent, surface active agent or a resin conventionally used in hair setting lotions. The compositions may be in the form of aqueous or aqueous-alcoholic solutions or a jelly or cream. Particularly preferred active compounds are the novel compounds #-[N#-hydroxymethylureyl] ethyldiethylamine, bis-[α- (N'-hydroxymethylureyl) propyl] methylamine and #-hydroxyethyl-N-hydroxymethylcarbamoylmethyldimethyl ammonium chloride.
Patent GB-1238711-A (GB)
IPC: F24D3/10
Filed: 1968-05-22
Abstract: 1,238,711. Central heating systems. F. S. HOWARD. 21 Aug., 1969 [22 May, 1968], No. 24510/68. Heading F4U. [Also in Division F2] A central heating installation comprises a radiator water circuit including a water heater and radiators with flow and return manifolds (11), flow manifold 11 being connected by connectors 15 and pipes 17 to the radiators and by end connector 12, 13 to the water heater pipe and return manifold 11 being connected by pipes 17 and connectors 16 to the radiators and by end connector 12, 13 to the water heater return pipe. The connectors may be of any suitable kind e.g. of the compression type. The manifolds may be connected in a sealed hot water circuit provided with a pump and a water heater and communicating with a water source through a non-return valve, an air vent valve being provided at an upper part of the circuit.