baber/WOPTO huggingface dataset:
Patent DE-69528103-T2 (DE)
Inventor: MEDLEN CONSTANCE ELIZABETH
IPC: A61K31/495
Filed: 1995-03-16
Granted: 2003-05-15
Abstract: The invention concerns the new use of riminophenazines in the treatment of a patient who has built up, or could build up, resistance to a therapeutically active substance, such as a patient requiring treatment for cancer. The riminophenazine conveniently may be of the general formula (I). <CHEM> R<1> is a hydrogen atom, a halogen atom or an alkyl, alkoxy or fluoroalkyl radical, R<2> is a hydrogen or halogen atom, R<3> is selected from hydrogen, alkyl, substituted alkyl, cycloalkyl, cycloalkylalkyl, or is a substituted or unsubstituted heterocyclic or heterocyclic-alkyl radical, R<4> is a hydrogen or halogen atom or an alkyl, alkoxy or fluoroalkyl radical, and n is 1, 2 or 3. The invention also provides novel riminophenazines of general formula (I), their preparation, and compositions containing them.
Patent DE-69530127-T2 (DE)
Inventor: LAIHO ERKKI
IPC: B32B27/32
Filed: 1995-05-16
Granted: 2003-09-11
Abstract: PCT No. PCT/FI95/00255 Sec. 371 Date Feb. 24, 1997 Sec. 102(e) Date Feb. 24, 1997 PCT Filed May 16, 1995 PCT Pub. No. WO95/32094 PCT Pub. Date Nov. 30, 1995The invention relates to a multilayer product for the production of packaging, the product comprising a carrier web (1), on one face of which there is disposed a tight multilayer coating (2) which includes a moisture-proof layer (b) and a gas-tight layer (a). The gas-tight layer is made up of a blend of an ethylene/vinyl alcohol copolymer and a polar ethylene polymer. The moisture-proof layer is polyolefin, preferably a blend of polyethylene and a polar ethylene polymer.
Patent DE-69530504-T2 (DE)
Inventor: CONRAD ERNEST
IPC: G05D11/00
Filed: 1995-11-03
Granted: 2004-03-25
Abstract: An apparatus for inserting a venturi tube having an inlet, an aspirator inlet and an outlet directly within a fluid flow stream, with the aspirator inlet not in contact with the fluid flow stream is disclosed. A plate having a first aperture leading to the venturi inlet, and a series of second apertures both supports the venturi within a conduit and divides the fluid flow stream into a first stream which flows through the venturi tube and a second stream which flows around the venturi tube. A variety of adjusting mechanisms are disclosed for varying the cross sectional area of the second apertures relative to the cross sectional area of the venturi tube. The apparatus is adapted to allow the back pressure within the venturi tube (which increases as the fluid flow rate increases) to force an increasing proportion of the flow stream to flow around the venturi tube in order to maintain a relatively constant aspiration rate within the venturi tube. The adjustment mechanisms disclosed include a second plate, similar to the first plate, which is manually rotated and a blocking ring which moves responsive to changes in rate of flow of the fluid flow stream.
Patent DE-69531505-T2 (DE)
Inventor: MIYAI KIYOSHI
IPC: C12Q1/6888
Filed: 1995-12-27
Granted: 2004-06-17
Abstract: A method and a reagent for detecting cells of a living organism contained in various samples of the organism by detecting genes specific for each animal species. This method is useful for detecting bleeding into feces. It is possible for confirming the bleeding of the human body to use an Alu sequence as the sequence specific for the animal species. As genes are used as the index in this method, fecal occult blood can be detected more specifically at a higher sensitivity than by the conventional technique using hemoglobin as the index.
Patent DE-69534946-T2 (DE)
Inventor: CARSON A
IPC: G01N33/50
Filed: 1995-11-01
Granted: 2006-12-28
Abstract: The invention is directed to methods for introducing biologically active peptides into a host by administration of polynucleotides which operatively encode for the peptide of interest. In a preferred embodiment of the invention, a host who has been identified as having a tumor bearing at least one tumor-associated antigen is the recipient of a polynucleotide which operatively encodes for a foreign mimic of the tumor-associated antigen or a mutation of the self-antigen. The antigen-encoding polynucleotides are administered to host tissues which have a high concentration of antigen presenting cells in them relative to other host tissues. The method is particularly useful in treating cancer through induction of antigen-specific cytotoxic T lymphocytes in the host for lysis of tumor cells bearing the antigen. Devices and compositions for use in the methods of the invention are also described.
Patent DE-69535323-T2 (DE)
Inventor: STONE PAUL ANDREW
IPC: B21B37/00
Filed: 1995-12-18
Granted: 2007-06-28
Abstract: The invention is concerned with a method of forging a part of a predetermined shape from a workpiece comprising the steps of: 
radially closing opposed forging dies such that the forging dies move radially inward in a predetermined direction to contact the workpiece wherein the opposed forging dies define a cavity therebetween of the predetermined shape of the resulting part; 
applying axial and radial force to the workpiece with the radially closing forging dies, said applying step including the step of generating compressive and shear stresses within the workpiece such that the workpiece deforms outwardly to the predetermined shape defined by the opposed forging dies; and 
structurally reinforcing the opposed forging dies during the application of compressive and shear forces with a die housing which receives and circumferentially encompasses the opposed forging dies during the forging process.
Patent DE-69535632-T2 (DE)
Inventor: MOSCHEL CHARLES
IPC: F16C13/00
Filed: 1995-09-15
Granted: 2008-08-28
Abstract: A roll system for use particularly in a papermaking press nip for dewatering a fibrous web, comprising a roll disposed so as to rotatingly cooperate with another roll in a press nip, the roll having a helical sensor for sensing pressure exhibited on the roll, and transmitting pressure signals to a processor as the roll rotates. Trigger signals are generated at certain times as the roll rotates, the time of the occurrence of the trigger signal representing a specific location on the helical sensor. The pressure signals are coordinated with the trigger signals, such that the pressure corresponds to the angular position of the roll where it is sensed. The operator may thus be given a visual or audible indication of the existence of non-uniformities in pressure sensed at various locations along the roll, thereby enabling corrective action to be initiated if necessary.
Patent DE-69610930-T2 (DE)
Inventor: ARVERUS HAKAN
IPC: B05D1/12
Filed: 1996-08-09
Granted: 2001-06-07
Abstract: A method and a powder for powder coating in which objects (2) which are to be powder coated are prepared in order to temporarily retain the powder, whereafter the powder is applied onto the object in a layer which is retained on the object until the powder, by means of melting and transformation to a solid state by means of curing, is caused to form a coating layer on the surfaces of the object. The powder is prepared in order to have a low melting and softening temperature below about 100  DEG C and preferably 60-100  DEG C, and comprises an initiator system arranged to bring the powder material to curing under the influence of electromagnetic radiation. The powder prepared in this way is heated on the object to a temperature such that it melts and forms an adherent layer on the coated surfaces of the object. Thereafter, this layer is subjected to the radiation, thus curing it to a coating layer covering the powder-coated surfaces.
Patent DE-69611356-T2 (DE)
Inventor: BURNS EUGENE
IPC: C07C309/42
Filed: 1996-03-04
Granted: 2001-07-19
Abstract: The synthesis of phenol sulfonate esters of alkanoyl amino acids is conducted in the presence of aqueous base to provide bleach activator compounds. Thus, the acid chloride of N-nonanoyl-6-aminocaproic acid is reacted with the sodium salt of p-phenol sulfonate in the presence of water at a pH in the range of about 9 to about 12 to yield the corresponding phenol sulfonate ester. The synthesis of the phenol sulfonate ester of the monononyl amide of adipic acid is also illustrated.
Patent DE-69621688-T2 (DE)
Inventor: MARTIN WALLACE ANTHONY
IPC: B65B25/00
Filed: 1996-03-29
Granted: 2002-11-28
Abstract: A packaging arrangement for the containment of at least one hydrophilic contact lens in a sterile aqueous solution. More specifically, pursuant to the packaging arrangement, a plurality of disposable hydrophilic contact lenses are contained in a specific number of individual packaging arrangements collectively housed in a box-like container or carton so as to provide a specified or essentially measured supply of contact lenses for use by a consumer over a predetermined period of time.
Patent DE-69623773-T2 (DE)
Inventor: SHNELL JAMES H
IPC: F24J3/08
Filed: 1996-06-07
Granted: 2003-01-30
Abstract: A system for the generation of electricity from geothermal energy that is less expensive, more efficient, and avoids dealing with undesirable byproducts, is disclosed. The system of the present invention relies on using endothermic reactions at the bottom of a well to capture and store the geothermal heat, and exothermic reactions at the top of the well to release the heat stored within the products of the endothermic reactions. In the preferred embodiment, the endothermic reaction is the dehydrogenation of ethanol. To induce the endothermic reaction as well as to harvest and separate the resulting products, a catalytic device is used where each type of product selectively diffuses into its individual conduit. The endothermic products undergo the exothermic reaction in a combustion turbine, and the products of the exothermic reaction are immediately condensed in a condenser. In the preferred embodiment the condenser condenses ethanol vapor into a liquid to be returned down the well, thus creating a closed system.
Patent DE-69624259-T2 (DE)
Inventor: PLOUET JEAN
IPC: C07K16/42
Filed: 1996-12-20
Granted: 2003-09-18
Abstract: An anti-idiotypic vascular endothelial growth factor antibody, an Fab fragment, and pharmaceutical compositions thereof, being ligands of the human KDR receptor or of the murine flk-1 receptor and not a ligand of fit are provided.
Patent DE-69627590-T2 (DE)
Inventor: HANOVER BARRY K
IPC: A61B6/00
Filed: 1996-08-02
Granted: 2004-04-08
Abstract: A C-arm apparatus. An X-ray imaging system is coupled to a C-arm, including an X-ray source and an image receptor mounted upon opposing locations, respectively on the C-arm. The C-arm is mass balanced about its axis of orbital rotation and is pivotally coupled to an articulating arm assembly supported upon a wheeled support base. The mass balance enables repositioning of the X-ray imaging system between an anterior-posterior view and an orthogonal lateral view with a single, orbital movement of the C-arm which also causes the views to define an imaging isocenter. The C-arm is preferably miniaturized to an approximate diameter of twenty-eight inches with a source-to-image distance of approximately fourteen inches. <IMAGE>
Patent DE-69632307-T2 (DE)
Inventor: PIONTEK JOSEPH
IPC: A61M5/14
Filed: 1996-01-03
Granted: 2005-01-13
Abstract: An apparatus and method are disclosed for modifying a liquid enteral nutritional product during delivery thereof from a supply to a feeding tube delivering the modified liquid enteral nutritional product to the gastrointestinal tract of a patient. At least one beneficial agent not in controlled release dosage form in a useful, dose unit, amount, is disposed within a formulation chamber so as to be taken up in a liquid enteral nutritional product traversing the formulation chamber while feeding the modified nutritional product into the gastrointestinal tract of a patient. The beneficial additive(s) are selected from nutrients, medicaments, probiotics, or diagnostic agents, or mixtures thereof, each in a dosage form that is dispersible in the medium of the liquid enteral nutritional product in less than two hours.
Patent DE-69632916-T2 (DE)
Inventor: COSFORD NICHOLAS D
IPC: C07F7/08
Filed: 1996-04-04
Granted: 2005-07-14
Abstract: In accordance with the present invention, there is provided a class of pyridine compounds which are modulators of acetylcholine receptors. The compounds of the invention displace acetylcholine receptor ligands from their binding sites. Invention compounds may act as agonists, partial agonists, antagonists or allosteric modulators of acetylcholine receptors, and are useful for a variety of therapeutic applications, such as the treatment of Alzheimer's disease and other disorders involving memory loss and/or dementia (including AIDS dementia); disorders of attention and focus (such as attention deficit disorder); disorders of extrapyramidal motor function such as Parkinson's disease, Huntington's disease, Gilles de la Tourette syndrome and tardive dyskinesia; mood and emotional disorders such as depression, panic, anxiety and psychosis; substance abuse including withdrawal syndromes and substitution therapy; neuroendocrine disorders and dysregulation of food intake, including bulimia and anorexia; disorders of nociception and control of pain; autonomic disorders including dysfunction of gastrointestinal motility and function such as inflammatory bowel disease, irritable bowel syndrome, diarrhea, constipation, gastric acid secretion and ulcers; pheochromocytoma; cardiovascular dysfunction including hypertension and cardia arrhythmias, comedication in surgical procedures, and the like.
Patent DE-69636863-T2 (DE)
Inventor: WILSON M
IPC: A61K38/00
Filed: 1996-02-23
Granted: 2007-11-15
Abstract: A method of reducing immune response during gene therapy is provided which involves co-administration of the viral vector bearing a therapeutic transgene and a selected immune modulator capable of inhibiting the formation of neutralizing antibodies and/or CTL elimination of the vectors upon repeated administration.
Patent DE-69705426-T2 (DE)
Inventor: GILG BERNARD
IPC: C08L25/06
Filed: 1997-12-11
Granted: 2002-05-23
Abstract: The invention relates to a composition comprising a) a styrene, alpha-methylstyrene or p-methylstyrene homo- or copolymer; b) a bromine-containing flame retardant; c) a UV absorber; d) a sterically hindered amine and e) an epoxidized fatty acid. This invention also relates to the use of the light stabilizer mixture consisting of the components c), d) and e) for light-stabilizing a styrene, alpha-methylstyrene or p-methylstyrene homo- or copolymer finished with a bromine-containing flame retardant as well as to a process for the light-stabilization thereof. Adding an epoxidized fatty acid to a UV absorber and a sterically hindered amine in styrene, alpha-methylstyrene or p-methylstyrene homo- or copolymer finished with bromine-containing flame retardants results in an unexpected synergistic effect in the light stability. In particular, it is possible to markedly reduce the discoloration of the finished polymer which takes place in the course of irradiation.
Patent DE-69707261-T2 (DE)
Inventor: GIOVANNOZZI SERMANNI GIOVANNI
IPC: D21C5/00
Filed: 1997-01-31
Granted: 2002-05-02
Abstract: Apparatus for the production of cellulose paper pulps from vegetative masses, comprising: a tower for sterilizing the mass to form a culture medium; a first screw for mixing the sterilized mass with an inoculum and handling the same in a sterile environment; a first conditioning and reaction chamber for mixing and handling the inoculated mass in a sterile environment and controlled atmosphere of CO2 and O2, with controlled temperature and pH; a hydraulic pulper for the elementarization of the mass and its soaking up with suspensions of enzyme mixes; a hammer mill for the elementarization of vegetative material, to break up knots of stems and to pulverize leaves, detach bast from wood; a rotating tumbler having reels and counter reels for separating various fractions; a rotor compactor to reduce the volume of the vegetable mass and to remove air contained in the same; a second screw for mixing the compacted vegetetative mass with extracts containing enzymes and with water for handling in a sterile environment; a second conditioning and reaction chamber having means for mixing and handling of the vegetative mass mixed with the enzymes in a sterile environment and controlled temperature of CO2 and O2, with controlled temperature and pH.
Patent DE-69713513-T2 (DE)
Inventor: WESTON EDWARD
IPC: A61M5/24
Filed: 1997-09-22
Granted: 2002-10-31
Abstract: A method and apparatus are described for making an article such as the body of a needleless injector capsule, from a formable material, such as glass, the article having a cavity communicating with the exterior via an orifice. A blank having an open end is mounted on a first forming tool, and the open end is engaged by a second forming tool while an end region of the blank adjacent the open end is in a condition to permit it to be formed. One of the tools has a pin extending therefrom, and when the tools are brought together to form the end region into the desired shape the pin defines the orifice.
Patent DE-69713969-T2 (DE)
Inventor: BOERS PAUL ARIS
IPC: B26D3/06
Filed: 1997-08-29
Granted: 2003-02-20
Abstract: A method for cutting a recess (13) in foam material (8), wherein by means of a first and a second knife (2,3) two cuts are provided in a surface of a foam-made block (8) or like object through a relative, linear movement of the object relative to the knives, wherein the first and the second knife (2,3) include an angle relative to each other and wherein, during use, the material located between the cuts and the contour of the object is removed for forming the or each recess (13), wherein at least the or each second knife (3) is substantially circular, is mounted on a central axis of rotation (15) and, during use, is driven in a rotational sense, wherein during use, the axis of rotation (15) is at least partly located within the contour of the object (8), in such a manner that during cutting, the relevant knife (3) extends within the contours of the object (8). <IMAGE>
Patent DE-69814181-T2 (DE)
Inventor: RODRIGO ANTHONY
IPC: G10L15/18
Filed: 1998-09-22
Granted: 2004-03-04
Abstract: A speech control system and method are provided in which state definition information is loaded from a network application server. The state definition information defines possible states of the network application server and is used to determine a set of valid commands of the network application server. A validity of a text command obtained by converting an input speech command can be checked by comparing the text command with the determined set of valid commands. Thus, a transmission of erroneous text commands to the network application server can be prevented so as to reduce total processing time and response delays.
Patent DE-69830072-T2 (DE)
Inventor: GREFF J
IPC: A61N5/00
Filed: 1998-11-03
Granted: 2006-01-19
Abstract: Disclosed are novel radioactive compositions which are particularly suited for treating solid mass tumors via catheter delivery.
Patent DE-69912038-T2 (DE)
Inventor: BERSELLI FRANCESCO
IPC: F16H1/20
Filed: 1999-07-19
Granted: 2004-10-07
Abstract: The invention relates to a speed reducing device (59;59'), comprising a box body (59") for housing and supporting a set number of gear pairs (67,68,72,83,95,96,103) kinematically connected to each other and to an input shaft (82;102) and to an output shaft (66) of the speed reducing device itself (59;59'); the box body (59") is defined by a casing (60), presenting substantially the shape of a cup body and supporting a set number of gears (67,68,72) kinematically connected to each other, and by a cover (61;62) connectable to the casing (60) to close the casing (60) itself, supporting an additional set number of casings (83 or 95,96,103); to the cover (61,62) is associated, or not, internally to the box body (59") and in respective different embodiments ofthe speed reducing device (59;59'), a wall (76) for supporting a part (95,96) of the additional set number of gears (95,96,103). <IMAGE>
Patent DE-69916678-T2 (DE)
Inventor: SHINPEI OKAJIMA
IPC: A43C7/08
Filed: 1999-02-19
Granted: 2004-09-23
Abstract: The invention relates to a shoe lacing configuration where short straps attached to sides of an article of footwear are formed with loops. At least one long strap extends through the loops in the one pair of the short straps, the long strap extending from side to side of the article of footwear. The long strap is further formed with loops at either end thereof. A lace extends through the loops in the long strap. The long strap has the effect of doubling the force applied to the lace on the short straps in a manner similar to that of a block and tackle thus improving the lace tightening characteristics of the article of footwear.
Patent DE-69916877-T2 (DE)
Inventor: HUNKAPILLER MICHAEL W
IPC: C12Q1/6834
Filed: 1999-08-24
Granted: 2005-03-24
Abstract: The present invention concerns methods of assembly of a polynucleotide on a solid-support by performing steps of annealing, ligation, and extension. The steps may be repeated in a cyclical manner to assemble immobilized double- or single-stranded polynucleotides with functional gene properties. The immobilized polynucleotides may be amplified by the polymerase chain reaction, and detected and quantitated by an exonuclease assay with a self-quenching, fluorescent probe. The polynucleotide may be cleaved from the solid-support by chemical or enzymatic cleavage.
Patent DE-69922492-T2 (DE)
Inventor: BERGENWALL MARTIN
IPC: H04L12/56
Filed: 1999-01-05
Granted: 2005-11-10
Abstract: The invention relates to a cellular radio network and a method of connecting a base station (100) to a cellular radio system, which enable a fast and automatized installation of base stations wherever an IP information network is available, the cellular radio system comprising a base station system which comprises as network elements a base station controller (102) and at least one base station, and in which method the base station controller controls at least one base station. The invention is characterized in that the network elements (102, 100) are interconnected by an information network using a packet protocol, and that each network element is provided with a unique network element address, and that the network configuration information of said information network using the packet protocol is maintained at a configuration server (104) connected to the information network, and that a new base station connected to the network first contacts the configuration server, and that the configuration server transmits the network configuration information to the base station.
Patent DE-69928382-T2 (DE)
Inventor: YOSHIKAWA TOSHIKAZU
IPC: A61P9/10
Filed: 1999-01-05
Granted: 2006-06-22
Abstract: An agent for preventing and curing the hindrance of ischemic reperfusiton is disclosed which has as an active component thereof a chromanol glycoside represented by the following general formula: <CHEM>   wherein R<1>, R<2>, R<3>, and R<4> independently denote a hydrogen atom or a lower alkyl group, R<5> denotes a hydrogen atom, a lower alkyl group, or a lower acyl group, X denotes a monosaccharide residue or an oligosaccharide residue which may have a lower alkyl group or a lower acyl group substituted for the hydrogen atom of the hydroxyl group of the saccharide residue, n denotes an integer of 0 - 6, and m denotes an integer of 1 - 6­. The agent, even in a small dosage, acts safely and effectively on the affected part and allows the hindrances of ischemic reperfusion induced in heart, stomach, small intestine, liver, spleen, kidney, brain, and skin, and the hindrance induced during the transplantation of an internal organ to be prevented and cured.