baber/WOPTO huggingface dataset:
Patent AT-E282413-T1 (AT)
Inventor: WILCOX CHRISTOPHER S
IPC: A61K31/40
Filed: 1998-09-21
Granted: 2004-12-15
Abstract: The present invention encompasses methods of treating patients for essential hypertension. The invention also includes related pharmaceutical compositions of nitroxides. Specific drugs, such as 4-hydroxy-2,2,6,6-tetramethyl-1-piperidinyloxy (Tempol) are disclosed. These compositions are also contemplated for use in the treatment of oxidative stress and modulation of blood pressure.
Patent AT-E476192-T1 (AT)
Inventor: STERN DAVID
IPC: C12P21/08
Filed: 1998-10-09
Granted: 2010-08-15
Abstract: The present method provides for an isolated peptide having an amino acid sequence corresponding to the amino acid sequence of a V-domain of a receptor for advanced glycation end product (RAGE). The present invention also provides for an isolated peptide having an amino acid sequence A-Q-N-I-T-A-R-I-G-E-P-L-V-L-K-C-K-G-A-P-K-K-P-P-Q-R-L-E-W-K (Seq. ID No. 1). The present invention provides for a pharmaceutical composition comprising a therapeutically effect amount of an isolated peptide having an amino acid sequence corresponding to the amino acid sequence of a V-domain of RAGE. The present invention also provides for a method for inhibiting interaction of an amyloid-² peptide with a receptor for advanced glycation end product which is on the surface of a cell, which comprises contacting the cell with the peptide or a functionally equivalent agent, wherein the peptide or agent is capable of inhibiting interaction of the amyloid-² peptide with the receptor for advanced glycation end product, and the peptide or agent is present in an amount effective to inhibit interaction of the amyloid-² peptide with the receptor for advanced glycation end product.
Patent AT-E460420-T1 (AT)
Inventor: HUTTON KYLE
IPC: A23D7/00
Filed: 1998-12-07
Granted: 2010-03-15
Abstract: The invention relates to a process for producing and refining phosphatides (phospholipids) including lecithin. Unlike previous procedures, the claimed process does not use acetone as a solvent, thereby yielding an acetone-free product suitable for animal or human consumption or for use as a pharmaceutical. The process produces phosphatides or lecithin with > 90 A.I.
Patent AT-E277232-T1 (AT)
Inventor: BARAGGIA PAOLA MARIA
IPC: E01H1/12
Filed: 1999-04-12
Granted: 2004-10-15
Abstract: A device (1) for collecting organic waste from ground comprises containment flexible means (2) which are operatively coupled to collecting means (5), the flexible means (2), which are made of an impermeable material, being provided for winding on the collecting means (5), to provide an impermeable space for engaging therein the collecting means (5), and a further impermeable space for holding therein the organic waste. <IMAGE>
Patent AT-E212877-T1 (AT)
Inventor: EYHORN THOMAS
IPC: B01J35/04
Filed: 1999-11-04
Granted: 2002-02-15
Abstract: Microporous material (I) comprising a finely divided metal oxide and non-health-hazardous fibers has a density of 100-250 kg/m<3> and an elasticity such that, when subjected to a pressure of 1 bar for 5 minutes, its thickness is reduced by at least 4% just before relieving the pressure and at least 70% of the lost thickness is regained 1 minute after relieving the pressure. Independent claims are also included for the following: (1) production of (I) by intensively mixing the individual components and pressing the mixture; and (2) a catalytic converter comprising a catalytic monolith fixed to a housing by means of (I).
Patent AT-E387806-T1 (AT)
Inventor: ALLRED JOSEPH
IPC: G06T5/00
Filed: 1999-11-11
Granted: 2008-03-15
Abstract: A method and apparatus for reducing noise and motion artifacts in pixels of a processed or displayed video image by filtering pixel values of the video image based on a first frame having currently stored (filtered) pixel values and a second frame having recently captured but not yet filtered pixel values. The apparatus includes a spatial filter for computing a motion value of a pixel of interest by averaging difference values of selected pixels surrounding the pixel of interest. Also included is a filter function means for producing an output difference value of the pixel of interest based on the motion value and an adder for adding the output difference value to the first frame filtered pixel value of the pixel of interest. Thus, each pixel of the video image is filtered according to the amount of motion in the video image. <IMAGE>
Patent AT-E256591-T1 (AT)
Inventor: DUNCAN IAN JAMES
IPC: B63H1/26
Filed: 1999-02-05
Granted: 2004-01-15
Abstract: A propulsion system for a water craft having at least one shaft extending rearwardly form the transom of the hull of the craft and a drive system for driving the at least one shaft. A surface piercing propeller is mounted on the at least one shaft, proximal to the trailing edge of the hull, so that the propeller operates in a transom cavity created behind the hull, in use of the craft. The ratio (S/C) of the spacing of the blades to the blade cord for each propeller is at least 2.0 along substantially the whole length of the blades. The propulsion system has a high operational efficiency particularly suited for high speed marine craft.
Patent AT-E301775-T1 (AT)
Inventor: PERSSON PER
IPC: F02M35/10
Filed: 1999-02-02
Granted: 2005-08-15
Abstract: An internal combustion engine is disclosed including at least two cylinders, each including an inlet port, an air inlet manifold for providing air to the cylinders, at least two outlets for emitting exhaust gases from the cylinders, a recirculation conduit for reducing harmful emissions from the exhaust gases and extending from one of the outlet for recirculating the exhaust gases from an outlet to a connection point in the air inlet manifold thereby defining a first volume from the outlet to the connection point, the air inlet manifold being divided into at least two further volumes defined by the distance between the connection point to each of the inlet points, at least one turbine for recovering energy from the exhaust gases, and a compressor for compressing air supplied to the air inlet manifold, the first volume and the further volumes being dimensioned such that the recirculated exhaust gases are substantially equally distributed between each of the cylinders.
Patent AT-E359490-T1 (AT)
Inventor: DANNER DALE R
IPC: F41A21/02
Filed: 1999-01-21
Granted: 2007-05-15
Abstract: A composite barrel for a firearm comprising a substantially metallic liner and fiber reinforced resin, in which the fiber reinforced resin is under compression.
Patent AT-E261483-T1 (AT)
Inventor: SWAGER TIMOTHY
IPC: C09K11/06
Filed: 1999-05-05
Granted: 2004-03-15
Abstract: The present invention relates to a class of luminescent and conductive polymer compositions having chromophores, and particularly solid films of these compositions exhibiting increased luminescent lifetimes, quantum yields and amplified emissions. These desirable properties can be provided through polymers having rigid groups designed to prevent polymer reorganization, aggregation or pi-stacking upon solidification. These polymers can also display an unusually high stability with respect to solvent and heat exposures. The invention also relates to a sensor and a method for sensing an analyte through the luminescent and conductive properties of these polymers. Analytes can be sensed by activation of a chromophore at a polymer surface. Analytes include aromatics, phosphate ester groups and in particular explosives and chemical warfare agents in a gaseous state. The present invention also relates to devices and methods for amplifying emissions by incorporating a polymer having an energy migration pathway and/or providing the polymer as a block co-polymer or as a multi-layer.
Patent AT-E249835-T1 (AT)
Inventor: KHAN NISAR AHMED
IPC: A61K45/00
Filed: 1999-05-20
Granted: 2003-10-15
Abstract: The invention relates to the field of immunology, more specifically to the field of immune-mediated disorders such as allergies, auto-immune disease, transplantation-related disease or inflammatory disease. The invention provides among others an immunoregulator (IR), use of an IR in preparing a pharmaceutical composition for treating an immune-mediated disorder, a pharmaceutical composition and a method for treating an immune-mediated disorder.
Patent AT-E216567-T1 (AT)
Inventor: BOIS HENRI GEORGES
IPC: A44B19/16
Filed: 1999-06-17
Granted: 2002-05-15
Abstract: A bag including two generally parallel sheets forming the main walls of the bag, complementary closure strips fixed to respective ones of the sheets, and a cursor for actuating the strips for closing and opening purposes. The bag further includes, parallel to the closure strips, between the sheets, and level with the mouth of the bag, additional structure in relief disposed on the insides of the closure strips, designed to provide sealing by forming a barrier between the sheets in the closed position of the bag, the additional structure in relief being placed facing the flanks of the cursor to be urged towards their sealing position by the cursor when the cursor is moved towards the sealing position.
Patent AT-E342298-T1 (AT)
Inventor: BENGS HOLGER
IPC: C08B30/04
Filed: 1999-08-14
Granted: 2006-11-15
Abstract: The present invention relates to a method for the production of small spherical particles consisting totally or partly of at least one water-insoluble linear polysaccharide by dissolving the at least one water-insoluble polysaccharide in a solvent or a solvent mixture, introducing the solution into a precipitating agent or a precipitating agent mixture, optionally cooling the mixture thus obtained and separating the formed small particles, wherein at least one poly alpha D-glucan soluble in hot water is used as auxiliary agent for precipitation. The invention also relates to the particles obtained according to said method.
Patent AT-E268798-T1 (AT)
Inventor: EDWARDS CHRISTOPHER M
IPC: C08J5/04
Filed: 1999-08-18
Granted: 2004-06-15
Abstract: Physical properties of polymer resins, particularly amorphous resins such as ABS or SAN copolymers, are markedly improved by dispersing therein a filler-reinforced engineering thermoplastic polyurethane.
Patent AT-E220159-T1 (AT)
Inventor: AUER KARL-HEINZ
IPC: E04B2/74
Filed: 1999-09-18
Granted: 2002-07-15
Abstract: Partition wall comprising at least one wall element (5) connected to a column (6) by a connecting element (1). The column (6) has a plurality of grooves distributed along its periphery and suitable for interacting with the connecting element (1). The wall element (5) has a connection profile (9) with at least one groove (11) on the edge side bordering on the column. The connecting element (1) has two clamping flanges (2,3) parallel to each other and interconnected by a connecting rod (4), wherein one flange is received in a groove (15) of the column (6) and the other flange is received in a groove (11) of the wall element (5). One (2) of the clamping flanges (2,3) of the connecting element (1) is received in the corresponding groove (11;15) in a rotationally fixed manner while the other clamping flange (13) is received in the corresponding groove (15;11) in such a way that it can rotate around its longitudinal axis (12) within a predetermined angular area.
Patent AT-E278273-T1 (AT)
Inventor: PIETERSE ROB
IPC: H04H60/25
Filed: 1999-10-07
Granted: 2004-10-15
Abstract: From a central database (1) audio/video files are transferred to local processing means (2). A processor (4) selects a collection of files (1') and stores these in a selection file (5'). The selection file and the selected files are transferred to the local processing means, which play the selected files. The processor periodically replaces part of the collection of local files by new files selected from the database. The processor can also select different collections of files and transfer these to the local processing means. The local processing means then comprise a local selection device for selecting selection files according to the desire of the subscriber, by means of which the files are "played" locally. For refreshing of the local files the local selection device stores the local selections and the central processor reads out those selections and replaces a part of the local collection.
Patent AT-E253860-T1 (AT)
Inventor: D ESTAIS MATHIAS
IPC: A47K5/02
Filed: 1999-11-25
Granted: 2003-11-15
Abstract: A washing agent dispenser including a washing agent case sized and shaped to hold a solid or solidified washing agent, and means for attachment of the case to a support or a surface, the case enabling collection of a surface sample of the washing agent by means of a washing instrument.
Patent AT-E373704-T1 (AT)
Inventor: ANDERSEN VILBOUR KIM
IPC: C12N15/09
Filed: 1999-12-20
Granted: 2007-10-15
Abstract: Subtilase enzymes of the I-S1 and I-S2 sub-groups having an additional amino acid residue in position 101 of the active site loop (b) region from position 95 to 103. Variant subtilases exhibit improved wash performance in a detergent in comparison to its parent enzyme.
Patent DE-385892-T1 (DE)
IPC: A61C13/30
Filed: 1990-02-27
Abstract: This prosthesis is of the type comprising, on the one hand, a plug 8 intended to be introduced into the canal lumen of the tooth, and whose end projecting beyond the latter is connected to an outer restoration element, with a crown or the like, and, on the other hand, a sheath fitting between the plug and the wall of the canal lumen. 
<??>According to the invention, its sheath 7 is in the shape of a conical sleeve, has a length equal to that of the plug, and is made of fibres having a high mechanical strength forming a structure which is deformable and porous to resin, has an outer fibrous covering, and is connected to a resin 6 of low surface tension capable of covering the wall of the canal lumen 3, of filling the dental tubules 5, of impregnating the fibres of the sheath 7, and of fixing the plug 8, the sheath 7 and the fibrous covering inside the canal lumen 3, with a view to obtaining a composite monobloc structure matching the canal lumen. 
<IMAGE>
Patent ES-2233223-T1 (ES)
Inventor: PELLARIN FLORENT
IPC: H04B1/20
Filed: 2003-05-23
Abstract: The method of equipment control device has transmitter commands and receiver commands monitoring the equipment (15). Commands are sent from the transmitter (20) to the receiver (10) with information concerning ergonomic features available on the command transmitter. Then a memory (16) is selected from the command receiver and a previously placed list corresponding to ergonomic features of the command transmitter established allowing the ergonomics of the command transmitter to be translated into command executable by the equipment.
Patent ES-2733020-T1 (ES)
Title: Monitorizar y predecir telemáticamente un estado de batería del vehículo
Inventor: DAVIDSON MARK JEFFREY
IPC: G05B23/02
Filed: 2018-12-19
Abstract: Un método de monitorización de una batería de un vehículo, comprendiendo el método: recibir una pluralidad de señales de tensión que indican un cambio en tensión de la batería en tiempos asociados con una pluralidad de arranques de un motor de arranque del vehículo; determinar, para cada una de la pluralidad de señales de tensión, una tensión máxima y una tensión mínima de la señal de tensión, para generar una pluralidad de tensiones máximas y una pluralidad de tensiones mínimas durante un periodo de tiempo; determinar una varianza en la pluralidad de tensiones mínimas durante el periodo de tiempo; generar una predicción de un estado de la batería basándose al menos en parte en la pluralidad de tensiones máximas, la pluralidad de tensiones mínimas, y la varianza de la pluralidad de tensiones mínimas.
Patent ES-2040194-T1 (ES)
IPC: A61K47/34
Filed: 1991-02-07
Abstract: Solid salts of cross-linked acrylic acid polymers or copolymers with alkali or aliphatic amines, useful as thickening agents, a process for the preparation thereof and the use thereof in the chemical, pharmaceutical, cosmetic, textile, paper industries.
Patent ES-2107404-T1 (ES)
Title: Arrollador de cinturon con tensor de cinturon que incide en la bobina del cinturon.
Inventor: EBNER RALF
IPC: B60R22/46
Filed: 1997-03-12
Abstract: UN ENROLLADOR DE CINTURON CON UN TENSOR QUE ENGRANA EN EL CARRETE (12) DEL CINTURON A TRAVES DE UN PRIMER MECANISMO (22,24) DE ACOPLAMIENTO, SE CARACTERIZA POR UNA CARCASA (10), UN DISPOSITIVO AUTOMATICO DE BLOQUEO, SENSIBLE AL CINTURON Y/O AL VEHICULO, DEL CARRETE (12) DEL CINTURON Y DOS MECANISMOS (32,40) DE ACOPLAMIENTO, QUE ESTABLECEN UN FLUJO DE FUERZA ENTRE LA CARCASA (10) Y EL CARRETE (12) DEL CINTURON UNA VEZ QUE SE HA TENSADO EL CINTURON MEDIANTE UN MOVIMIENTO DEL CARRETE (12) EN LA DIRECCION DE DISPARO DEL CINTURON. EL PRIMER MECANISMO (22,24) DE ACOPLAMIENTO ESTA EN EL LADO DE SALIDA DE LA FUERZA Y EL SEGUNDO MECANISMO (32,40) DE ACOPLAMIENTO EN EL LADO DE ENTRADA DE LA FUERZA, ESTANDO UNIDO CON EL PRIMER EXTREMO DE UNA BARRA (30) DE TORSION, CUYO SEGUNDO EXTREMO ESTA CONECTADO AL CARRETE (12) DEL CINTURON. SE HA PREVISTO ADEMAS UN DISPOSITIVO (42,44,46) DE INACTIVACION, UNIDO CON EL SEGUNDO MECANISMO (32,40) DE ACOPLAMIENTO, DEL DISPOSITIVO AUTOMATICO DE BLOQUEO. EL SEGUNDO MECANISMO (32,40) DE ACOPLAMIENTO ESTA COORDINADO CON AL MENOS UN APOYO FLEXIBLE RADIAL, QUE, A TRAVES DEL TENSADO DEL CINTURON, PERMITE EL DESPLAZAMIENTO DE LAS PARTES (32,40) DEL SEGUNDO MECANISMO DE ACOPLAMIENTO Y SU ENCASTRE. EN EL APOYO PREVIO RESULTANTE DEL TENSOR DEL CINTURON DE LOS OCUPANTES DE UN VEHICULO, EL SEGUNDO MECANISMO DE ACOPLAMIENTO SE ENCUENTRA EN SITUACION ENCASTRADA, EVITANDOSE ASI TODO RETARDO EN LA RETENCION DE LOS OCUPANTES.
Patent ES-2127174-T1 (ES)
Title: Cabrestante de cordon que incluye un organo de embrague/desembrague, destinado para maniobrar el arbol porta celosia de una persiana enrollable.
Inventor: JEUNOT ALAIN
IPC: E06B9/78
Filed: 1998-07-01
Abstract: LA INVENCION SE REFIERE A UN TORNO DE CINTA QUE CONSTA DE UNA CARCASA EN LA QUE VA ALOJADO UN ORGANO REDUCTOR (6) ENTRE LA PARTE TORNO Y LA PARTE UNIDA AL ARBOL PORTACORTINA DE LA PERSIANA ARROLLABLE. EL TREN DE ENGRANAJE QUE FORMA EL ORGANO REDUCTOR VA PROVISTO DE UN SISTEMA DE FIN DE CARRERA. SE CARACTERIZA POR QUE LA CARCASA (1) CONSTA DE UNA POLEA (4) ACCIONADA EN ROTACION POR UNA CINTA (5) Y SOLIDARIA DEL REDUCTOR (6) A TRAVES DE UN ARBOL DE ENTRADA (25) COAXIAL A DICHA POLEA (4). EL ARBOL DE ENTRADA (25) ESTA RODEADO POR UNA GUARNICION (15) QUE CONFORMA CON ESTE ULTIMO UN SISTEMA DE EMBRAGADO/DESEMBRAGADO. EL CONJUNTO VA ALOJADO EN EL INTERIOR DE LA POLEA (4), QUE COOPERA, JUNTO CON EL REDUCTOR (6), CON LA PARTE SOLIDARIA DEL ARBOL PORTACORTINA (9) MEDIANTE UN SISTEMA DE FRENADO ANTIRRETROCESO QUE COMPRENDE AL MENOS DOS ORGANOS (39) DEFORMABLES ELASTICAMENTE Y MONTADOS EN TANDEM.
Patent ES-2307473-T1 (ES)
Inventor: CHEN CHAO
IPC: A23B7/10
Filed: 1998-08-10
Abstract: Methods of preserving fresh fruit with fresh fruit preservatives which extend the shelf life of fresh fruit particularly fresh cut fruit, are provided. The fresh fruit preservative preserves the texture, flavor, appearance, crispness, and color of the fresh fruit, particularly the exposed skin of the fresh fruit. The method comprises the following steps: providing a solution of fruit preservative comprising: water, calcium ions; and ascorbate ions, wherein the calcium ion and ascorbate ions are present in a ion ratio of preferably from about 1.5:1 to about 2.5:1; and, applying said fruit preservative to the fruit. Preferably the fruit is then stored at a temperature which will not freeze the fruit; temperatures of -6 °C have been found not to freeze the apples. Preferably the fruit is stored at temperatures of between about -7 °C to room temperature, about 20 °C, more preferably about -2 °C to about 7 °C, most preferably from about 2 °C to about 5 °C. The invention also relates to fresh fruits preserved with the fresh fruit preservatives.
Patent CY-1108180-T1 (CY)
Inventor: MIHARA MASAHIKO
IPC: A61K38/00
Filed: 2008-07-08
Abstract: A preventive and/or therapeutic agent for systemic lupus erythematosus comprising an anti-interleukin-6 (IL-6) receptor antibody as an active ingredient.
Patent CY-1109698-T1 (CY)
Inventor: ARSLANIAN ROBERT L
IPC: C07D405/06
Filed: 2009-12-30
Abstract: Recombinant  Myxococcus  host cells can be used to produce polyketides, including epothilone and epothilone analogs that can be purified from the fermentation broth and crystallized.
Patent CY-1111376-T1 (CY)
Inventor: VOGT SEBASTIAN DR
IPC: B01F15/02
Filed: 2011-04-05
Abstract: The mixing device has a discharge tube (3) arranged in an opening (4) in a direction of a longitudinal axis in a displaceable manner. A mixing disk (5) is arranged at an end of the discharge tube, where the end is arranged inside a mixing cylinder (1). The mixing disk is provided with multiple mixing openings and a central outlet. The mixing disk is arranged between a closed front side i.e. screw cap (2), and a bottom of the mixing device. A handle (9) is fixed to the opposite end of the discharge tube in a detachable manner.
Patent CY-1114601-T1 (CY)
Title: Χρηση της αλλοπουρινολης για την αγωγη της δερματικης αντιδρασης χειρος-ποδος
Inventor: RODEMER YOLANDA
IPC: A61K31/519
Filed: 2013-11-13
Abstract: Χρήση της αλλοπουρινόλης ή ενός φαρμακευτικά αποδεκτού άλατος αυτής για την αγωγή ή πρόληψη της Δερματικής Αντίδρασης Χειρός Ποδός (HFSR) που επάγεται από τη θεραπεία με Αναστολέα Κινάσης Πολλαπλών Στόχων (ΜΚΙ). Η αλλοπουρινόλη ή το άλας της χορηγείται τοπικά στις πληγείσες περιοχές, στις παλάμες και στα πέλματα, κατά προτίμηση υπό τη μορφή μιας κρέμας.
Patent CY-1116718-T1 (CY)
Title: Βιοιατρικος διανομεας αιμοστατικης σκονης
Inventor: FOSTER CLARK
IPC: A61M5/30
Filed: 2015-09-28
Abstract: Ένας βιοϊατρικός διανομέας αιμοστατικής σκόνης (1) μέσω του οποίου εξατομικευμένες δόσεις φαρμακευτικής αγωγής σε μορφή σκόνης που έχουν αποθηκευτεί σε αντίστοιχους θαλάμους ενός περιστρεφόμενου μεταφορέα (22) ρευστοποιούνται για τη μεταφορά σε μια στοχευμένη περιοχή θεραπείας (για παράδειγμα, μια πληγή προκειμένου να σταματήσει η αιμορραγία). Ειδικότερα, μια λαβή συμπίεσης (7) ενεργοποιείται (για παράδειγμα, συμπιέζεται) προκειμένου να προκαλέσει την εφαρμογή μιας ριπής αερίου υπό πίεση από έναν συλλέκτη αερίου (30) σε έναν θάλαμο ειδικότερο από τους θαλάμους που είναι γεμάτοι με σκόνη του περιστρεφόμενου μεταφορέα της φαρμακευτικής αγωγής, έτσι ώστε μια εξατομικευμένη δόση φαρμακευτικής αγωγής που έχει μετρηθεί να εγκλωβίζεται και να μεταφέρεται στον ασθενή. Την ίδια στιγμή που μια λαβή συμπίεσης ενεργοποιείται, ο περιστρεφόμενος μεταφορέας με τη φαρμακευτική αγωγή περιστρέφεται προκειμένου ένας διαφορετικός θάλαμος γεμάτος με σκόνη να μετακινηθεί μέσα στη δίοδο του υγρού ανάμεσα στον συλλέκτη αερίου και σε έναν αγωγό με ακροφύσιο εξόδου (10) του διανομέα και μια θήκη για τη διανομή της σκόνης.
Patent CY-1117239-T1 (CY)
Title: Συνδυαστικες συνθεσεις διπλοκοκκου του neisser
Inventor: GIULIANI MARZIA MONICA
IPC: A61K38/16
Filed: 2016-03-01
Abstract: Συνθέσεις οι οποίες περιέχουν ένα πρώτο βιολογικό μόριο από βακτήριο Neisseria και ένα δεύτερο βιολογικό μόριο από βακτήριο Neisseria. Ο όρος "βιολογικό μόριο" περιλαμβάνει πρωτεΐνες και νουκλεϊκά οξέα. Προτιμώμενα είδη Neisseria είναι τα N. meningitidis (μηνιγγιτιδόκοκκος) και N.gonorrhoeae (γονόκοκκος του Neisser).
Patent CY-1118973-T1 (CY)
Title: Παραγωγα αμιδιου βενζοϊμιδαζολο-καρβοξυλικου οξεος για τη θεραπεια μεταβολικων ή καρδιαγγειακων νοσηματων
Inventor: HACHTEL STEPHANIE
IPC: C07D487/06
Filed: 2017-04-25
Abstract: Η παρούσα εφεύρεση αναφέρεται σε ενώσεις αμιδίου βενζοϊμιδαζολο-καρβοξυλικού οξέος του τύπου I, στον οποίο τα R', R", R"', R1, R2, R3, R4, R5, R6 και Ζ ορίζονται όπως υποδεικνύεται παρακάτω. Οι ενώσεις του τύπου I είναι ρυθμιστές υποδοχέα APJ και είναι χρήσιμες για τη θεραπεία των νοσημάτων που συνδέονται με αυξημένη πίεση αίματος για παράδειγμα. Η εφεύρεση περαιτέρω σχετίζεται με τη χρήση των ενώσεων του τύπου I, ιδιαίτερα ως δραστικά συστατικά σε φαρμακευτικές ουσίες και φαρμακευτικές συνθέσεις που τις περιέχουν.