baber/WOPTO huggingface dataset:
Patent UA-60439-A (UA)
Title: Technique for assaying metallothionein in biological objects
Inventor: SHAFRAN LEONID MOISEIOVYCH
Filed: 2002-06-25
Abstract: The technique for assaying metallothionein (MT) in the biological objects is based on the detection of cadmium upon its precipitation with the specified reagent, in particular the inorganic salt, calcium carbonate, for example. MT is assayed employing the atomic absorption spectrometry.
Patent UA-60568-A (UA)
Title: Method for surgical treatment of intraparenchymal cysts in kidneys
Inventor: SARYCHEV LEONID PETROVYCH
Filed: 2003-01-02
Abstract: The method for the surgical treatment of the intraparenchymal cysts in the kidneys comprises the percutaneous access to the cyst, the cystoscopy, and the generation of the permanent draining opening connecting intraparenchymal and subcapsular cysts. The drainage of the intraparenchymal cyst is performed through the permanent draining opening generated in the non-vascular areas, first between the intraparenchymal and subcapsular cysts, finally, between the subcapsular cyst and the retroperitoneal space.
Patent AP-1656-A (AP)
Title: Rock breaking unit and apparatus
Inventor: JERLING PETER J
IPC: E21C25/04
Filed: 2002-12-16
Granted: 2006-09-01
Abstract: In one aspect the invention relates to a rock breaking unit which can be used to break rock non-expiosively. The unit (12) has an elongate tube (56) which is inserted in use into a hole (11) in a rock mass. There is also a propellant (64, 74) in the tube, a fuse (62, 72) associated with the propellant, and a capsule (66,76) of liquid (68, 78) in the tube adjacent the propellant and situated to be closer to the mouth of the hole than the propellant when the tube is inserted into the hole. When the propellant is ignited there is a rock breaking action which is contained by the liquid. In another aspect the invention relates to rock breaking apparatus (10) which includes the unit (12) together with a plug (14) that serves to anchor and seal the unit in the hole. The plug itself includes a central, hollow bolt 16 and radially expandable elements (36, 38, 86) on the bolt which are expanded into anchoring and sealing contact with the wall of the hole when the bolt is tensioned.
Patent DO-P2013000147-A (DO)
Title: Compuestos y su uso como inhibidores de bace
Inventor: CSJERNYIK GABOR
IPC: A61K31/4184
Filed: 2013-06-20
Abstract: La presente invención se refiere a compuestos de fórmula (I) y sus composiciones farmacéuticas. Asimismo, la presente invención se refiere a métodos terapéuticos para el tratamiento y/o la prevención de patologías relacionadas con Aß, como síndrome de Down, angiopatía ß-amiloide como, a modo no taxativo, angiopatía amiloide cerebral o hemorragia cerebral hereditaria, trastornos asociados con el deterioro cognitivo como, a modo no taxativo, MCI ("deterioro cognitivo leve"), mal de Alzheimer, pérdida de memoria, síntomas de déficit de atención asociados con mal de Alzheimer, neurodegeneración asociada con enfermedades como mal de Alzheimer o demencia, incluida demencia de origen vascular y degenerativo mixto, demencia presenil, demencia senil y demencia asociada con mal de Parkinson, parálisis supranuclear progresiva o degeneración corticobasal.
Patent DO-P2020000058-A (DO)
Title: Compuestos monobactámicos cromanos para el tratamiento de infecciones bacterianas
Inventor: WEIGUO LIU
IPC: A61K31/4439
Filed: 2020-03-16
Abstract: La presente invención se refiere a compuestos monobactámicos de la Fórmula I: (I) o una sal de estos farmacéuticamente aceptable. La presente invención también se refiere a composiciones que comprenden un compuesto monobactámico de la invención o una sal de este farmacéuticamente aceptable y un portador farmacéuticamente aceptable. La invención además se refiere a métodos de fabricación de medicamentos útiles para tratar una infección bacteriana que comprenden administrar al paciente una cantidad terapéuticamente eficaz de un compuesto de la invención, ya sea solo o en combinación con una cantidad terapéuticamente eficaz de un segundo antibiótico betalactámicos.
Patent DO-P2020000105-A (DO)
Title: Dispositivo desinfectante multiusos segun la invencion cuya finalidad es eliminar las bacteria y virus de cualquier, vehiculo, ascensor, articulo alimento, envase, utensilio, agujas y cuchillas o instrumental medico.
Inventor: PEDRO MANZANERO MUNUERA
IPC: A61L2/24
Filed: 2020-06-09
Abstract: Dispositivo desinfectante multiusos según la invención cuya finalidad es eliminar las bacteria y virus de cualquier, vehículo, ascensor, articulo alimento, envase, utensilio, agujas y cuchillas o instrumental médico de fácil movilidad y efectividad demostrada, expulsa una sustancia inocua para los humanos aunque letal en bacterias. Este invento se ha diseñado con una serie de características según las necesidad que surgen de prevención, diseñando un dispositivo multi facetico con distintas en formas y tamaños, pero siempre con el mismo común denominador la desinfección de un amplio abanico de objetos y artículos, así como todo aquello que sea susceptible de poder aplicarse le con el dispositivo según la necesidad siendo eficaz en zapatos, ropa, bolsos , alimentos, envases, vehículos, monedas, billetes, hojas de afeitar, agujas hipodérmicas, papel, instrumental médico, mascarillas, celulares., por lo que viene el dispositivo a cubrir un necesidad hoy no está resuelta.
Patent DO-P2023000035-A (DO)
Title: Proceso e intermediarios para preparar un inhibidor de jak
Inventor: WEIGUO LIU
IPC: C07C233/00
Filed: 2023-02-17
Abstract: La presente invención se relaciona con procesos para preparar ruxolitinib, o una sal de este, e intermediarios relacionados sintéticos asociados a estos.
Patent EC-SP11011108-A (EC)
Title: Piperidina espiro pirrolidinona y piperidinona sustituidas, su preparación y su uso terapéutico
Inventor: GAO ZHONGLI
IPC: A61K31/435
Filed: 2011-06-03
Abstract: La presente invención describe y reivindica una serie de carboxamidas N-fenil-bipirrolidina sustituidas de fórmula (I). Donde R1, R2, R3, m, n y p son como se describen en el presente documento. Más específicamente, los compuestos de esta invención son moduladores de los receptores H3 y, por lo tanto, son útiles como agentes farmacéuticos, especialmente en el tratamiento y/o prevención de una variedad de enfermedades moduladas por los receptores H3, incluyendo enfermedades asociadas con el sistema nervioso central. Además, la presente invención también describe métodos para la preparación de carboxamidas N-fenil-bipirrolidina sustituidas e intermedios para ello.
Patent EC-SP11011373-A (EC)
Title: Agentes terapeúticos inmunomoduladores
Inventor: MELLING MITCHELL J
IPC: A61K38/36
Filed: 2011-10-04
Abstract: Un grupo de péptidos ha sido aislado del suero de mamíferos domesticados y luego identificados a través de la utilización de la espectrometría de masas. Estos péptidos son productos derivados de la activación del fibrinógeno y de la cascada del complemento. Los péptidos de mayor actividad son las formas activadas de fibrinopéptido A y fibrinopéptido B (activado por la eliminación de la arginina terminal), y un fragmento inmunomodulador del componente del complemento 3. Estas formas de fibrinopéptidos A y B tienen la capacidad inmunomoduladora notable, mejorando el reconocimiento de sustancias extrañas, incluyendo los agentes infecciosos de todo tipo, disminuyendo la respuesta inflamatoria, previniendo la deposición de fibrina extravascular, estimulando la reabsorción de la fibrina que ya ha sido depositada, mejorando la capacidad del cuerpo para reconocer y eliminar las células neoplásicas, disminuyendo los síntomas de reacción alérgica que incluye la rinitis alérgica y la anafilaxia, reduciendo la formación y el depósito de los complejos de auto anticuerpos, mejorando los síntomas de enfermedades neurológicas crónicas y disminuyendo los síntomas de los síndromes de dolores crónicos.
Patent EC-SP12011749-A (EC)
Title: Fenilpiri(mi)dinilazoles
Inventor: DESBORDES PHILIPPE
IPC: C07D487/04
Filed: 2012-03-27
Abstract: Fenilpiri(mi)dinilazoles de la fórmula [I-a] y [I-b], en la que los símbolos tienen los significados indicados en la descripción y sales agroquímicamente activas de los mismos y el uso de los mismos para el control de microorganismos no deseados en la protección de plantas y materiales y para la reducción de micotoxinas en plantas y partes de plantas y procedimientos para la producción de compuestos de las fórmulas [I-a] y [I-b].
Patent GB-189702423-A (GB)
Title: Improvements in Nozzles for Spraying Machines, Garden and Firemen's Hose, Shower Baths, and similar Appliances.
Inventor: BLACK JOHN
Filed: 1897-01-29
Granted: 1897-06-12
Abstract: 2423. Black, J. Jan. 29. Nozzles; spray producers.-The nozzle is constructed to deliver a solid jet or a spray from the same orifice in the cap, Fig. 5. This cap contains another, Figs. 3 and 4, with a central orifice and helical surrounding passages, to which the liquid is respectively admitted through the passages c and b in the cock, Fig. 1, and delivered as a solid jet or a spray. It is applicable to watering gardens, extinguishing fires, shower baths, and other purposes.
Patent GB-189708198-A (GB)
Title: An Improved Hat Guard Device.
Inventor: STAHL JOHANN JAKOB
Filed: 1897-03-30
Granted: 1897-05-01
Abstract: 8198. Stahl, J. J. March 30. Guards.-Figs. 1 and 2 show vertical sections of the appliance at right-angles to each other. In a casing a is a spindle l to which is attached one end of a spiral spring b and on which is mounted a cogwheel c in gear with a smaller wheel d mounted on an axle l<1>, on which is a roller c on which a cord z forming the hat guard is wound. When the cord is pulled down the spring b is wound up under tension, and tends to draw back the cord, but is prevented by the spring-piece f of the casing, which is pivoted at i and presses against the cord ; in order to allow the spring b to act, the upper end of the piece f must be pressed inwards so as to remove its lower end from bearing against the cord.
Patent GB-189709587-A (GB)
Title: Improvements in Electric Measuring Instruments.
Filed: 1897-04-15
Granted: 1898-01-15
Abstract: 9587. Evershed & Vignoles and Evershed, S. April 15. Current and energy meters. -Am-meters and volt-meters such as those described in Specification No. 20,723, A.D. 1893, watt-meters, and similar instruments, especially those having horizontal axles for use on switchboards, are provided with air damping vanes and boxes to prevent oscillations. In the form shown, the axle A carries a sleeve T with two rectangular vanes V, within a closed circular box B, which has partitions P, only small clearances being left about the vane for the passage of air. The box B may form part of the frame of the instrument, being closed by two semicircular plates and carrying the scale in front, and supporting the coil &c. on its back. In a modification, each vane V carries a segmental extension within an annular channel around the partitions P, to afford more obstruction to the passage of air. In other modifications, the sleeve carries four vanes between four radial partitions such as P, or two vanes movable through nearly 180‹ between two partitions, or one vane may be used with a single radial partition, this arrangement allowing the axle to make nearly a whole revolution.
Patent GB-189712863-A (GB)
Title: Improvements in Lasting Machines Employed in the Manufacture of Boots and Shoes.
Inventor: BROOKES ALFRED GEORGE
Filed: 1897-05-25
Granted: 1897-08-21
Abstract: 12,863. Brookes, A. G., [International Goodyear Shoe Machinery Co.]. May 25. Lasting.-Relates to machines in which lasting- plates or wipers are employed for wiping the upper over the last at the toe and heel, and consists of a last band or clamp, to be carried by the wipers, and made in sections elastically connected, so that it can adjust itself to lasts of various sizes and shapes. The Figure shows a plan of the wipers or lasting - plates 10, which are pushed forward against the toe portion of the upper by the operating-mechanism of the machine, causing the edges of the plates to wipe and turn the edge of the upper over upon the last. The adjustable clamp, which is simultaneously operated for binding the upper to the last, consists of two or more blocks B, pivoted on studs which can slide in slots in the wipers, and connected by articulated sections A flexibly attached to them by springs W<1> or otherwise. The clamp carries the facing-pad C of leather, rubber, &c., which bears upon the upper and forces it into close contact with the last. A similar arrangement is used for lasting the heel portion of the upper.
Patent GB-189713735-A (GB)
Title: Improvements in Primary Batteries.
Inventor: ROWBOTHAM WALTER
Filed: 1897-06-03
Granted: 1898-05-28
Abstract: 13,735. Rowbotham, W. June 3. Primary batteries.-Relates to batteries of the kind described in Specification No. 2378, A.D. 1897, in which the separate cells B<1> are arranged in steps and the liquids circulate through them from the uppermost to the lowest. The positive electrode may be iron and the liquid in contact with it water, and the cock A<2> of the water cistern A is connected with a switch C' in such a manner that, when the switch is operated to break the battery circuit, the cock A<2> is opened and a stream of water flows through the battery so as to prevent local action on open circuit.
Patent GB-189715481-A (GB)
Title: Improvements in Tires.
Inventor: HODGMAN FREDERICK AUGUSTUS
Filed: 1897-06-29
Granted: 1897-07-31
Abstract: 15481. Hodgman, F. A. June 29. Tyres, elastic other than pneumatic.-In a rubber tyre A having a core B wholly enclosed by the body of the tyre, the ends b of the core are made to overlap and are provided on their faces with inclined interlocking teeth b<1> arranged to slip past each other as the tyre is compressed on the rim of a wheel, and to engage automatically with one another to prevent subsequent expansion of the tyre. In another form, in which the core of the tyre is in the form of a hollow tube, one end is reduced in diameter and provided with teeth adapted to engage with a. series of teeth on a sleeve secured inside the other end of the tube.
Patent GB-189717858-A (GB)
Title: Improvements in Rods for Portieres, Bedsteads, and the like.
Inventor: ASHWORTH ABRAHAM
Filed: 1897-07-30
Granted: 1898-05-07
Abstract: 17,858. Ashworth, A. July 30 Curtains, drawing and suspending.-The rods for portiÞre or bedstead curtains are made with the ornamental part a<1> in duplicate, so that the curtain slides between them. The rings c slide on a rod or in a groove, and two or more of them can be connected to a rod d sliding in a groove so as to move simultaneously.
Patent GB-189719424-A (GB)
Title: Electrical Glow Light.
Inventor: NERNST WALTHER
Filed: 1897-08-23
Granted: 1898-05-28
Abstract: 19,424. Nernst, W. Aug. 23. Drawings to Specification. Incandescent gas lamps.-A body of magnesia, zirconia, or suitable rare oxide, sulphide, fluoride, silicate, or other non-conductor of electricity, is heated to incandescence by a Bunsen gas flame or otherwise, and is then kept incandescent by the passage of electric current through it, using a pressure of 100 volts or more, as desired. The flame may be retained or removed after starting. The incandescent body may be a rod held between metal springs, and is preferably unenclosed.
Patent GB-189721577-A (GB)
Title: Improvements in Leaf Holders or Clips and Book Markers.
Inventor: SPIELMAN MARY ELIZABETH
Filed: 1897-09-21
Granted: 1897-11-06
Abstract: 21,577. Spielman, M E. Sept. 21. Leaf-holders.-Clips, composed of thin spring arms 3 turned up at one end and connected at the other by arms 4, 5, guided by a pin 7 and slots, or by a sleeve 11, and connected by a screw 8 with or without a nut 9, a r e engaged with the leaves on each side of an open book. A pair of clips may be connected by a chain. The clips do not prevent a leaf from being turned, and, when the book is closed, act as a book marker.
Patent GB-189726403-A (GB)
Title: Improvements in or relating to Pneumatic Tyres for Bicycles and other Road Vehicles.
Inventor: GOODWIN JOSEPH HENRY
Filed: 1897-11-12
Granted: 1898-11-12
Abstract: 26,403. Goodwin, J. H. Nov. 12. Tyres, pneumatic.- Puncture is prevented by means of a rubbercovered steel hoop A either flat or slightly curved in cross-section, which is placed within the tread so as to protect the inner air tube. The ends of the hoop are fastened together by rivets or by a steel plate and rivets, the joint being enclosed in a canvas cover.
Patent GB-189803652-A (GB)
Title: Improvements in or connected with Bedsteads.
Inventor: BUCHANAN ROBERT HENRY
Filed: 1898-02-14
Granted: 1898-03-26
Abstract: 3652. Buchanan, R. H. Feb. 14. Bedsteads; cradles.-A cradle or crib 1 is supported on the side rail of a bedstead by hooks 6, the outer side being supported by folding legs 7 which may be held in the folded position by turnbuttons 9. The end frames 3 fold down, and then the front 4 folds on them, theparts being held folded by the hook 5 and staple 5<a>. In the unfolded position, the hook 5 engages another staple on the end frame 3. The legs 7 may be in two parts 10 and 11, one slotted and adjustably connected to the other by clamping-bolts 13. The hooks and the face of the rail abutting against the bedstead rail may be covered with cloth to prevent damage.
Patent GB-189809711-A (GB)
Title: Improvements in or connected with Pneumatic Wheel-tyres.
Inventor: PULBROOK ANTHONY
Filed: 1898-04-27
Granted: 1899-04-27
Abstract: 9711. Pulbrook, A. April 27. Tyres, pneumatic; felloes or rims. - Relates primarily to tyres having the tread part separate from the part which lies within the rim, the latter part being attached to the rim either by the means described in Specification No. 9697, A.D. 1897, or by an inextensible textile strip which is solutioned over the part lying within the rim and is impregnated either with rubber solution or with the mixture described in Specification No. 14,839, A.D. 1895. The overlapping edges A', D' of the tread part A and rim part D respectively are stiffened, and are secured together either by lacing; or by hooking the edges ; or by fixing into one edge A' bolts, buttons, or studs which are passed through shaped holes in the other edge D<1> and are fixed by nuts, pins, or wires, as shown in Fig. 1. Flaps F may cover the overlapped edges, and the inner air tube I may be dispensed with. Fig. 12 shows a form having, in each edge of the tread part A, a tube A<2> which is filled with fluid and is held in a corresponding groove R<1> in the rim R by means of the plate P. In the modification shown in Fig. 14, each edge of the tread part has an attaching-wire W, and the tubes A<2> are connected with the flaps F. This form may be employed as a tubeless tyre, the circular rubber band giving an airtight joint. To repair a puncture, a rubber patch G, Fig. 16, is applied in the usual way, and over the patch a larger strip S of leather, fish skin, or the like solutioned. The strip is secured by lacing L round the rim, and it may have metallic protectors and small airtight compartments filled with fluid.
Patent GB-189812262-A (GB)
Title: Improvements in Barrel Hoops.
Inventor: BAUER JOHN GEORGE
Filed: 1898-05-31
Granted: 1898-07-09
Abstract: 12,262. Bauer, J. G., and Bauer, J. M. May 31. Hoops for the bilge of casks are formed of a narrow strip 1 to which a broad strip 4 is riveted, the latter having a perforation 5 to permit of the insertion and withdrawal of the bung.
Patent GB-189812882-A (GB)
Title: Improvements in Steam Engines.
Inventor: SMITH THOMAS
Filed: 1898-06-09
Granted: 1899-05-20
Abstract: 12,882. Smith, T., Smith, W. H., and Eastwood, W., [trading as Smith Bros. &: Eastwood]. June 9. Valves, distributing and expansion.-Relates to engines of the Corliss type which are not provided with variable cut-off or trip gear for the admission valves, and consists in providing one or two separate semi-rotary or oscillating cut-off valves. In Fig. 1, A, A are the exhaust valves, and B, B the steam valves, all actuated by a wrist-plate D. C, C are the cut-off valves, actuated by a wristplate E which is oscillated by any ordinary gear. One cut-off valve may be made to serve both admission valves.
Patent GB-189813044-A (GB)
Title: Improvements in Pattern Lags for Looms for Weaving.
Inventor: THOMPSON WILLIAM PHILLIPS
Filed: 1898-06-10
Granted: 1899-04-29
Abstract: 13,044. Thompson, W. P., [R³egg, J., and Schelling, W.]. June 10. Loom pattern lags and pegs for dobbies or shaft machines. The pegs C are formed of strips, preferably of metal, the ends of which are bent or corrugated for attachment to flat strips b<1>, b<2> by insertion into slots b<0> therein, the strips being let into grooves in a wooden base a. The slots may be numbered.
Patent GB-189816573-A (GB)
Title: Improvements in Siphon Heads.
Inventor: HUSTED CHARLES LOUIS
Filed: 1898-07-29
Granted: 1898-11-12
Abstract: 16,573. Husted, C. L. July 29. Siphon bottles.-The discharge of the liquid is regulated by a valve g<3> controlled by a spring K and operated by a lever h which fits into a hollow part B of the valve. The strength of the spring K is such that any undue pressure in the bottle itself causes the valve g<3> to be opened. The cap C allows the siphon head to be repaired without removing it from the bottle A.
Patent GB-189816673-A (GB)
Title: Improvements in Bedsteads for the Use of Invalids.
Inventor: MCKNIGHT ALEXANDER
Filed: 1898-07-30
Granted: 1898-11-19
Abstract: 1 6 , 6 7 3 . McKnight, A. July 30. Bedsteads; tables; mattresses. - The invalid rests on a mattress z supported by a bed bottom connected by springs to the side bars of a frame a, the head and foot sections of which are pivoted to the side bars B<1> of the bed. The head section, with its cross-bar at b<1>, is pivoted at x to the bracket d, and has an arm f acted on by a spring F so as to tend to raise the head section, which, when adjusted, is fixed by a projection on the hinged handle h<3> fitting into one of a series of notches in the fixed plate g. The pivot x and cross-bar b<1> are out of line with the side bar a as shown. The leg section is pivoted at y, and is raised by a winch K and cord K<1> which is attached to an arm 0 so that the foot may be inclined as shown by the dotted lines. The leg section carries a hinged foot part E'. To the fabric of the stationary central section is fixed a frame G, Fig. 20, to carry a commode G<2> which has an opening to clear the patient's body when the commode is slid aside, a flap l<2> covering this opening to prevent draughts. A handle is provided at m, Fig. 2, an overflow pipe at m<1>, and a removable seat frame at G<1>. The mattress has an opening above the commode, and elsewhere if desired, covered by an air cushion with bevelled edges. The patient is raised for changing the bed by passing broad strips beneath him, hooking these to the side bars of a frame, and raising the frame by cords J<1> passing over pulleys j, j<3> and attached to winches J. This frame has hinged end bars which can bend only one way and are kept rigid by sliding tubes. The cord passes freely through a hole in the barrel of the winch so as to equalize the pull at each corner of the bed. The bed is fitted with a spittoon on a hinged arm and with a table S, Fig. 4, the arms w of which slide into tubes w<1> pivoted to the bed at w<2> and adjusted by the cord. The whole bed may be raised for surgical operations, or tilted as shown by the dotted lines in Fig. 4, by fixing the cord J<1> to stationary hoisting-legs M and turning the winches J. A weight attached to a cord running over a pulley may be provided for stretching the patient's limbs.