baber/WOPTO huggingface dataset:
Patent WO-2023164537-A1 (WO)
Title: Composés pyrazolyles utilisés en tant qu'activateurs de canal kv7
Inventor: RESNICK LYNN
IPC: A61K31/40
Filed: 2023-02-23
Abstract: L'invention concerne des pyrazolylacétamides éventuellement substitués, des compositions pharmaceutiques comprenant une quantité thérapeutiquement efficace de tels composés et un excipient pharmaceutiquement acceptable, et des procédés de traitement de maladies ou de troubles, tels que l'épilepsie, la sclérose latérale amyotrophique, divers types de douleur, l'hyperexcitabilité, une dyskinésie, la dystonie, la manie, l'acouphène, des maladies ou des troubles neurodéveloppementaux, un trouble de la contractilité des muscles lisses, le syndrome de Dravet, le trouble de stress post-traumatique (PTSD), avec de tels composés et compositions pharmaceutiques.
Patent WO-2023192817-A1 (WO)
Inventor: RAI ROOPA
IPC: C07D213/46
Filed: 2023-03-27
Abstract: Provided herein are compounds of Formula (I). Methods for the preparation of the compounds of Formula (I) and intermediates useful in the preparation of the compounds of Formula (I) are described herein. The compounds of Formula (I) may be useful as inhibitors of the MYST family of lysine acetyltransferases (KATs) for the treatment of and/or prophylaxis of hyperproliferative diseases, disorders or conditions such as cancer. In particular, the compounds of Formula (I) are useful for the inhibition of KAT6A and KAT6B which are enzymes frequently mutated, overexpressed, amplified and/or translocated in cancer altering their normal expression, activity and function. The use of the compounds of Formula (I) in the manufacture of pharmaceutical compositions or for treating cancers is further described, including for treating cancer in combination with other anti-cancer agents.
Patent WO-2023240003-A1 (WO)
Inventor: JAFARIAN-TEHRANI SEYED
IPC: H01J37/32
Filed: 2023-05-25
Abstract: Procédé mis en œuvre à l'intérieur d'une chambre à plasma. Le procédé consiste à fournir un premier signal de puissance à un mandrin électrostatique (ESC). Le procédé consiste à fournir un second signal de puissance à un anneau de bord. Le procédé consiste à mesurer une amplitude d'un signal de courant se produisant au niveau d'une interface entre l'ESC et l'anneau de bord. Le procédé consiste à ajuster un ou plusieurs paramètres du premier signal de puissance et du second signal de puissance pour obtenir une amplitude minimale du signal de courant. Le procédé consiste à déterminer une relation de phase entre une phase du signal de courant et une phase d'un signal de référence pour déterminer une direction d'inclinaison d'ions au niveau de l'interface. Le procédé consiste à ajuster au moins un paramètre du second signal de puissance pour obtenir un angle prédéterminé de l'inclinaison d'ions au niveau de l'interface sur la base de la relation de phase et de l'amplitude du signal de courant.
Patent DK-201970480-A1 (DK)
Title: Hsmi disease resistance in salmonids
Inventor: Jacob Seilø Torgersen
IPC: C12Q1/6883
Filed: 2018-01-30
Abstract: The present invention relates to methods of predicting resistance to heart and skeletal muscle inflammation in salmonids, the method comprising determining the alleles present at a DNA polymorphism in the salmonid and predicting whether or not the salmonid is resistant to heart and skeletal muscle inflammation based on the determination of the alleles. The invention also relates to related methods of detecting, in a sample from a salmonid, the alleles present at a DNA polymorphism associated with resistance to heart and skeletal muscle inflammation, methods for obtaining an indication of risk of a salmonid developing heart and skeletal muscle inflammation, uses of such DNA polymorphisms, and methods of detecting, in a sample from a salmonid, one or more salmonid gene variants.
Patent DK-202270285-A1 (DK)
Title: Electronic device with hearing device based health characterization and/or monitoring and related methods
Inventor: SIGURD BRANDT
IPC: A61B5/16
Filed: 2022-05-31
Abstract: An electronic device is disclosed. The electronic device comprises a memory, an interface, and a processor. The processor is configured to obtain, via the interface, external sensor data from a hearing device; determine, based on the external sensor data, a health parameter, e.g. indicative of a cognitive state of a user of the hearing device. The processor is configured to determine whether the health parameter satisfies a first criterion indicative of a cognitive decline. The processor is configured, e.g. in accordance with the health parameter satisfying the first criterion, to output, e.g. via the interface, a health representation associated with the cognitive state.
Patent PH-12014502133-A1 (PH)
Title: Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use
Inventor: LEANNE BERRY
IPC: A61P35/00
Filed: 2014-09-24
Abstract: Combinations of the antibody-drug conjugate trastuzumab-MCC-DM1 and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting tumor cell growth, and for treating disorders such as cancer mediated by HER2 and KDR (VEGFR receptor 1). Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
Patent PH-12014502167-A1 (PH)
Title: Froth pump and method
Inventor: PAVOL LODERER
IPC: F04D7/04
Filed: 2014-09-26
Abstract: A pump (10) comprising a pump casing (20) having front and rear sides (23, 24) with a pumping chamber (38), a chamber inlet (26) and a discharge outlet (27). An impeller (40) within the chamber rotates about an axis. The chamber includes an inner region at or near the axis and an outer region remote from the axis within which is the discharge outlet. The impeller includes a shroud (42) having front and rear faces (43, 44) with a plurality of pumping vanes (46). A collection chamber (60) is provided at the rear side of the pump casing in fluid communication with the pumping chamber. The impeller includes one or more passageways (52) through the shroud, one end opening into the collection chamber and the other opening into the pumping chamber through the impeller front face. A flow inducer (70, 72) is within the collection chamber, which includes a venting outlet (62) and a transfer outlet zone in fluid communication with the outer region of the pumping chamber.
Patent PH-12015500174-A1 (PH)
Title: Container for liquids
Inventor: FRANS HANSSEN HUBERT JOSEPH
IPC: B65D21/02
Filed: 2015-01-27
Abstract: The invention relates to a container assembly (1) for liquids, such as beverages and oils, comprising a container (2), chimes (4, 6B) and a valve assembly (3) for feeding a propellant to and dispensing the liquid from the container (2). ? portion (4) of the assembly (1) has a polygonal cross-section, which cross-section at least partially circumscribes the cross-section ( s ) of the remainder of the assembly (1).
Patent PH-12015500584-A1 (PH)
Title: Reconfigurable processing enclosures
Inventor: MARSHALL MEDOFF
IPC: G21K5/04
Filed: 2015-03-17
Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) or other materials are processed to produce useful intermediates and products, such as energy, fuels, foods or materials. For example, systems and methods are described that can be used to treat feedstock materials, such as cellulosic and/or lignocellulosic materials, in a vault in which the walls and optionally the ceiling include discrete units. Such vaults are re-configurable
Patent PH-12015501925-A1 (PH)
Title: Hydrochloride salt of ((1s,2s,4r)-4-{4-[(1s)-2,3-dihydro-1h-inden-1-ylamino]-7h-pyrrolo [2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl)methyl sulfamate
Inventor: ARMITAGE IAN G
IPC: C07D487/04
Filed: 2015-09-01
Abstract: Disclosed is a compound of formula (I); crystalline forms thereof, and solvates thereof; pharmaceutical compositions comprising a pharmaceutically effective amount of the compound of formula (I), or a crystalline form thereof, or a solvate thereof, and a pharmaceutically acceptable carrier or diluent; and the use of a compound of formula (I), or a crystalline form thereof, or a solvate thereof, for treating a patient suffering from, or subject to, a pathological condition capable of being ameliorated by inhibiting an El activating enzyme, particularly NAE, including, e.g., cancer.
Patent PH-12016501064-A1 (PH)
Title: Motorcycle side cover structure
Inventor: KIYOSHI YANAGITA
IPC: B62J23/00
Filed: 2016-06-03
Abstract: Problem to be solved: to provide a side cover structure for a motorcycle having an engine mounted below and forward its seat, in which the side cover structure extends upwardly and rearwardly from below the seat along the length of the rear body cover and having a visually contiguous upwardly sloping ridgeline defining a widest span of the motorcycle to avoid overlaying a large, wide spatial area which will require large manufacturing molds and to improve comfort of a passenger when their feet are positioned on passenger steps. Solution: In a motorcycle having an engine mounted below and forward its seat, a side cover structure has a main pipe side cover that extends upwardly and rearwardly from below the seat along the length of the rear body cover and having a visually contiguous upwardly sloping ridgeline defining a widest span of the motorcycle in order to enable manufacturing using smaller manufacturing molds, and to convey a novel, impressive design. A cover element disposed adjacent to and below the main pipe side cover slants rearward and upward, until reaching or approximately reaching the ridge line of the rear body cover to reduce the extent to which a passenger needs to spread their legs, improves comfort and hold when their legs are rested over the side cover structure, improves holding and protects color coating when their feet are positioned on the passenger steps.
Patent PH-12016501638-A1 (PH)
Title: Computing long-term schedules for data transfers over a wide area network
Inventor: KANDULA SRIKANTH
IPC: H04L45/121
Filed: 2016-08-17
Abstract: Various technologies pertaining to scheduling network traffic in a network are described. A request to transfer data from a first computing device to a second computing device includes data that identifies a volume of the data to be transferred and a deadline, where the data is to be transferred prior to the deadline. A long-term schedule is computed based upon the request, wherein the long-term schedule defines flow of traffic through the network over a relatively long time horizon. A short-term schedule is computed based upon the long-term schedule, where devices in the network are configured based upon the short-term schedule.
Patent PH-12016502313-A1 (PH)
Title: Pharmaceutical composition comprising pyrazine carboxamide compound as active ingredient
Inventor: KONAGAI SATOSHI
IPC: A61P35/02
Filed: 2016-11-21
Abstract: [Problem] To provide a medicinal composition for treating cancer in which at least one kinase selected from among BTK, JAK3 and ITK participates. [Solution] As the results of studies on compounds having BTK inhibiting effect, JAK3 inhibiting effect and ITK inhibiting effect, the present inventors confirmed that specific pyrazine carboxamide compounds have BTK inhibiting effect, JAK3 inhibiting effect and ITK inhibiting effect, and medicinal compositions comprising these compounds as an active ingredient have therapeutic effect on cancers in which at least one kinase selected from among BTK, JAK3 and ITK participates, cancers in which BTK is overexpressed or activated in another embodiment, cancers in which B cell receptor signals are activated in a still another embodiment, cancers in which JAK3 is activation-mutated or activated in a still another embodiment, and cancers in which ITK is activated in a still another embodiment, thereby completing the present invention.
Patent PH-12017501687-A1 (PH)
Title: Inhibitors of hepatitis c virus polymerase
Inventor: JACOBSON IRINA C
IPC: C07D307/84
Filed: 2017-09-14
Abstract: The present invention provides, among other things, compounds represented by the general Formula I: (I) and pharmaceutically acceptable salts thereof, wherein L and A (and further substituents) are as defined in classes and subclasses herein and compositions (e.g., pharmaceutical compositions) comprising such compounds, which compounds are useful as inhibitors of hepatitis C virus polymerase, and thus are useful, for example, as medicaments for the treatment of HCV infection.
Patent PH-12019500563-A1 (PH)
Title: Fluid catalytic cracking process and apparatus for maximizing light olefin yield and other applications
Inventor: CHEN LIANG
IPC: C10G11/18
Filed: 2019-03-15
Abstract: Apparatus and processes herein provide for converting hydrocarbon feeds to light olefins and other hydrocarbons. The processes and apparatus include, in some embodiments, feeding a hydrocarbon, a first catalyst and a second catalyst to a reactor, wherein the first catalyst has a smaller average particle size and is less dense than the second catalyst. A first portion of the second catalyst may be recovered as a bottoms product from the reactor, and a cracked hydrocarbon effluent, a second portion of the second catalyst, and the first catalyst may be recovered as an overhead product from the reactor. The second portion of the second catalyst may be separated from the overhead product, providing a first stream comprising the first catalyst and the hydrocarbon effluent and a second stream comprising the separated second catalyst, allowing return of the separated second catalyst in the second stream to the reactor.
Patent PH-12019502565-A1 (PH)
Title: L-shaped crossarm, related system, and method of assembly
Inventor: ARLUND JOSHUA
IPC: H02G7/20
Filed: 2019-11-15
Abstract: The present disclosure relates to a mounting base for a crossarm and the crossarm. The mounting base may include a front-facing fastening surface, a rear-facing surface, and an opening formed between the front-facing fastening surface and the rear-facing surface, where the opening comprises a generally reverse L-Shaped geometry that extends through an entire width of the mounting base. The crossarm may include a first section and a second section that are oriented perpendicularly to each other, where the first section and second section are composed of composite material that contains a plurality of fibers within the composite material.
Patent PH-12020550999-A1 (PH)
Title: Set of panels
Inventor: BOO CHRISTIAN
IPC: E04F13/08
Filed: 2020-06-25
Abstract: A set of panels that includes a first panel (41) and a second panel(42)is provided. The first and second panels have a first, second and third edge.The first edge (1) of the first panel(41)is configured to be able to be locked together with both the second edge (2) and the third edge of the second panel(42). The first edge includes a first locking element (4) configured to be able to cooperate with a first locking groove (5) at the second edge (2) and a second locking groove (6) at the third edge for locking in a horizontal direction. The first edge includes a tongue groove (7) configured to cooperate with a tongue (8) at the second edge (2) and a tongue (9) at the third edge for locking in a vertical direction. The first locking element includes a first locking surface configured to cooperate with a second locking surface (11) on the first locking groove (5), for locking in the horizontal and the vertical direction. The first locking element includes a third locking surface (12) which is configured to cooperate with a fourth locking surface (13) on the second locking groove (6) for locking in the horizontal direction.
Patent PH-12021500013-A1 (PH)
Title: New heterocyclic compounds as monoacylgylcerol lipase inhibitors
Inventor: BELL CHARLES
IPC: C07D498/04
Filed: 2021-02-11
Abstract: The invention provides new heterocyclic compounds having the general formula (I) wherein A, L, X, m, n, R1 and R2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
Patent DE-102004001354-A1 (DE)
Title: Antenna for mobile telephone etc. has metal antenna element with connection part extending from side of substrate confined to predetermined position spaced apart from wiring board
Inventor: NAKAGAWA YOSHINOBU
IPC: H01Q1/36
Filed: 2004-01-08
Abstract: The antenna includes a resin or plastics substrate. An antenna element made of metal is attached to the substrate and includes a connection part that extends from the side of the. The substrate is confined to a predetermined position spaced apart from a wiring board. The connection part is sprung-connected to the wiring board. The antenna element is preferably of the monopole type with a zigzag folded structure. An independent claim is included for a wireless or radio device.
Patent DE-102004002870-A1 (DE)
Inventor: FRERICHS ARNOLD
IPC: A61M16/06
Filed: 2004-01-19
Abstract: The medical breathing mask has a body with a hose connection sealed to it and with a frontal support (20) which is adjustable. The front support has a flexible connecting strap (18) which is adjustable by sliding on a guide (19). The strap extends out of the guide and can be fixed in at least two positions.
Patent DE-102004003375-A1 (DE)
Title: Navigationsvorrichtung
Inventor: YATO NORIHISA
IPC: G09B29/00
Filed: 2004-01-22
Abstract: Eine derzeitige Zeit, die durch einen internen Takt A (41) angegeben wird, kann von einer ECU (4) geändert werden. Wenn ein Benutzer eine Startposition und ein Ziel über eine Fernsteuerung (6) eingibt, berechnet die ECU (4) eine Ankunftszeit an dem Ziel und zeigt die Ankunftszeit zusammen mit der derzeitigen Zeit auf einer Berührungsanzeige (5) an. Danach ändert die ECU (4), wenn der Benutzer ein Ändern der derzeitigen Zeit anweist, die derzeitige Zeit, die durch den internen Takt A (41) angegeben wird, um eine gegebene angewiesene Dauer. Die Ankunftszeit wird gleichzeitig um die gegebene angewiesene Dauer geändert.
Patent DE-102004006355-A1 (DE)
Title: Verringerung der Stromaufnahme in Datenverteilern
Inventor: LIM ALVIN SWEE HOCK
IPC: H04L12/56
Filed: 2004-02-10
Abstract: Ein Datenverteiler 1 enthält eine Verteiler-Engine 7 und Eingangs-/Ausgangsschnittstellen 5, die jeweils die Verteiler-Engine 7 mit einem einer Anzahl von Kanälen verbinden. Die Eingangs-/Ausgangsschnittstellen 5 und die Verteiler-Engine 7 bestehen jeweils aus einer Anzahl von Modulen (PHY, MAC_RX, RX, MAC_TX, TX, PBM, ARL, QM). Ein Teil der Module oder alle Module weisen eine Logikschaltung auf, um diese einzuschalten, wenn sie benötigt werden, um die Schaltung durchlaufende Datenpakete zu verarbeiten, und es ist eine Logikschaltung vorgesehen, um sie auszuschalten, wenn sie nicht mehr benötigt werden. Auf diese Weise werden die Stromversorgungsanforderungen des Verteilers 1 reduziert.
Patent DE-102004007327-A1 (DE)
Title: Rotor
Inventor: DOEBBELING KLAUS
IPC: F03D11/00
Filed: 2004-02-14
Abstract: Ein Rotor (11) einer thermisch belasteten Turbomaschine, insbesondere eines Kompressors (10) oder einer Gasturbine, ist um eine Rotorachse (21) drehbar gelagert und konzentrisch von einem Heißgaskanal (12) oder Kühlluftkanal umgeben. Eine deutliche Verbesserung der thermischen Belastbarkeit bei geringem materialtechnischem Mehraufwand wird dadurch erreicht, dass der Rotor (11) einen Rotorkern (22) aus einem ersten Material umfasst, dass der Rotorkern (22) konzentrisch von Abschirmringen (18) aus einem zweiten Material umgeben ist, welche den Rotorkern (22) gegen die Temperatur im Heißgaskanal (12) bzw. Kühlluftkanal abschirmen, wobei das zweite Material gegenüber dem ersten Material eine höhere Wärmefestigkeit aufweist, und dass die Abschirmringe (18) mit dem Rotorkern (22) stoffschlüssig verbunden sind.
Patent DE-102004007636-A1 (DE)
Title: Elektronisches Gerät mit einem lichtemittierenden/-erfassenden Anzeigebildschirm
Inventor: PAYNE DAVID M
IPC: G06F3/033
Filed: 2004-02-17
Abstract: Beispielhafte Verfahren, Vorrichtungen, Medien und Anordnungen ermöglichen die Implementierung von einem oder mehreren Merkmalen in elektronischen Geräten, die (z. B. Anzeige-) Bildschirme aufweisen, die für Lichtemission und -erfassung in der Lage sind. Diese Merkmale umfassen beispielsweise Abtasten, (simulierte) Berührungsbildschirmempfindlichkeit und Umgebungslichtbestimmung und -kompensation. Die Anzeigebildschirme können aus lichtemittierenden/-erfassenden Elementen bestehen, wie z. B. Dioden, die Licht für eine visuelle Anzeige emittieren können und Licht zum Empfangen von Lichtinformationsdaten erfassen können. Bei bestimmten beschriebenen Implementierungen umfaßt ein Verfahren zum Implementieren eines Merkmals unter Verwendung eines Anzeigebildschirms mit emittierenden/erfassenden Elementen folgende Schritte: Aktivieren mehrerer Elemente eines Arrays von Elementen zum Emittieren von Licht; Aktivieren mehrerer Elemente des Arrays von Elementen zum Erfassen von Licht; Erzeugen erfaßter Lichtdaten, die das Licht darstellen, das durch die mehreren Elemente erfaßt wird, die aktiviert sind, um Licht zu erfassen; und Verarbeiten der erfaßten Lichtdaten zum Implementieren des Merkmals.
Patent DE-102004020789-A1 (DE)
Title: Method for indicating colour settings for colour printing press has each zone setting given a digital value and an analogue grey scale of colour scale indicator
Inventor: DOELKER WOLFGANG
IPC: B41F33/02
Filed: 2004-04-28
Abstract: A simple method for indicating the colour settings for a colour printing press has each of the colour applicators (10 to 15) for the zones across a colour print given a digital value (23) to indicate the colour setting, as selected manually or by an automated control. Each setting is linked to an analogue display (16 to 21) in which the setting value is represented by a grey scale and/or colour scale, and/or brightness setting. This provides a clear indication to the operator of the printer settings. Similar systems are provided for each colour.
Patent DE-102004023641-A1 (DE)
Title: Vorrichtung mit Mitteln zum Verbinden mit einem Anti-Baby-Pillenblister oder zum Aufbewahren eines Anti-Baby-Pillenblisters und ein Anti-Baby-Pillenblister
Inventor: WIDMAIER CLAUDIA
IPC: A61J1/03
Filed: 2004-05-10
Abstract: Die Erfindung betrifft eine Vorrichtung (1, 7, 10, 12, 16, 20, 23) mit Mitteln zum Verbinden mit einem Anti-Baby-Pillenblister oder zum Aufbewahren (14, 22) eines Anti-Baby-Pillenblisters (8), einem Zeitgeber (3) und einem daran gekoppelten Signalgeber. Des Weiteren betrifft die Erfindung einen Anti-Baby-Pillenblister (8). DOLLAR A Die erfindungsgemäße Vorrichtung zeichnet sich dadurch aus, dass in den Zeitgeber (3) eine sich wiederholende 28-tägige Zeitperiode (28a, 28b) fest einprogrammiert ist, die abwechselnd eine 21-tägige Zeitphase (29) und eine 7-tägige Zeitphase (30) aufweist, wobei der Startzeitpunkt (32a, 32b) der 28-tägigen Zeitperiode (28a, 28b) einstellbar ist und während der 21-tägigen Zeitphase (29) der Signalgeber durch Abgabe von zumindest einem Signal (33) am Tag an die Einnahme der Anti-Baby-Pille erinnert. Der Anti-Baby-Pillenblister zeichnet sich dadurch aus, dass ein Zeitgeber (3) und ein daran gekoppelter Signalgeber auf dem Anti-Baby-Pillenblister (8) integriert sind.