baber/WOPTO huggingface dataset:
Patent WO-2020206098-A1 (WO)
Inventor: DANOS OLIVIER
IPC: C12N15/864
Filed: 2020-04-02
Abstract: Compositions and methods are described for the delivery of therapeutic products (such as therapeutic proteins (for example, antibodies), therapeutic RNAs (for example, shRNAs, siRNAs, and miRNAs), and therapeutic aptamers) to the retina/vitreal humour in the eyes of human subjects to treat pathologies of the eye, involving, for example, recombinant viral vectors such as recombinant adeno-associated virus (rAAV) vectors.
Patent WO-2020206187-A1 (WO)
Inventor: VILLEPONTEAU BRYANT
IPC: A61K35/76
Filed: 2020-04-02
Abstract: Le système de haute technologie selon la présente invention utilise des cellules souches adultes extraites à partir d'organes de mammifère individuels (tels que la graisse adipeuse, la moelle osseuse ou le sang) et rajeunit génétiquement les cellules souches adultes ex vivo jusqu'à un état fœtal jeune en utilisant de petites molécules chimiquement définies. Les cellules souches multipotentes régénérées sont ensuite multipliées de manière exponentielle ex vivo dans un bioréacteur automatisé dans de nouvelles conditions qui maintiennent la fonction de cellule souche jeune tout en réduisant fortement les risques de production de cellules souches cancéreuses.
Patent WO-2020219470-A1 (WO)
Inventor: BOROVINSKAYA MARINA
IPC: A61P35/00
Filed: 2020-04-21
Abstract: L'invention concerne des procédés d'administration continue, à un sujet ayant besoin d'un traitement, d'une formulation comprenant un composé imide immunomodulateur. Dans certains modes de réalisation, le procédé est destiné à être utilisé dans le traitement du myélome multiple, de l'anémie dépendant de la transfusion due à des syndromes myélodysplasiques à risque faible ou intermédiaire 1, d'un lymphome à cellules du manteau, de cancers hématologiques ou de cancers à tumeur solide.
Patent WO-2021076186-A1 (WO)
Title: Techniques for privacy-preserving data processing across multiple computing nodes
Inventor: JANKLY STEVE P
IPC: G06F21/60
Filed: 2020-04-27
Abstract: A method used in a first environment (102) includes obtaining (402) first data (304b) to be processed in a second environment (104), homomorphically encrypting (410) the first data to produce first encrypted data (304d), and providing (410) the first encrypted data to the second environment. The method also includes receiving (412) supplemental data (332) from the second environment, homomorphically encrypting (414) the supplemental data to produce encrypted supplemental data (333), and providing (414) the encrypted supplemental data to the second environment. The method further includes receiving (416) second encrypted data (304e) from the second environment and homomorphically decrypting (418) the second encrypted data to recover data processing results (311b) generated in the second environment using the first encrypted data and the encrypted supplemental data.
Patent WO-2020227610-A1 (WO)
Title: Dynamic routing of vehicles through established corridors
Inventor: SAHIN MUSTAFA
IPC: G01C21/26
Filed: 2020-05-08
Abstract: A computing system can assign a transport request to a high capacity vehicle (HCV) corridor of a plurality of HCV corridors, where the HCV corridor is associated with a plurality of possible rendezvous locations and a plurality of possible routes that can be traveled by individual HCVs. The computing system can determine, from the transport request of the requesting user, an optimal pick-up location from the plurality of possible rendezvous locations of the HCV corridor for an HCV to rendezvous with the requesting user.
Patent WO-2020236809-A1 (WO)
Title: Direct drive refrigerant screw compressor with refrigerant lubricated rotors
Inventor: QIU YIFAN
IPC: F04C29/00
Filed: 2020-05-19
Abstract: Disclosed is a direct-drive refrigerant screw compressor, having: a housing; a compression chamber in the housing; a pair of rotors, each rotor of the pair of rotors being rotationally disposed in the compression chamber and including an outer surface with a screw-geared profile; a fluid being disposed in the compression chamber, the fluid consisting of a working fluid for providing lubrication to each rotor; a first port extending through the housing and configured for directing the fluid toward the compression chamber; and when the compressor is activated, each rotor rotates and the fluid is distributed about each rotor to lubricate each rotor.
Patent WO-2020237174-A1 (WO)
Inventor: AL-YAMI ABDULLAH
IPC: C04B28/00
Filed: 2020-05-22
Abstract: Disclosed are methods of preparing drilling fluid compositions containing treated calcium bentonite. One such method includes mixing calcium bentonite with an aqueous mixture containing soda ash, followed by adding starch to form the treated bentonite mixture that is used to prepare a drilling fluid composition. Another method includes mixing the calcium bentonite with an aqueous mixture containing soda ash and magnesium oxide, followed by adding starch to form the treated bentonite mixture that is used to prepare a drilling fluid composition.
Patent WO-2020252203-A1 (WO)
Title: Deodorant compositions
Inventor: PLESCIA MARISA ANN
IPC: A61K8/34
Filed: 2020-06-11
Abstract: This disclosure relates to topical personal care compositions comprising one or more of a yeast component; a  Bacillaceae  extract; and 13-methyltetradecanoate; and B) one or more of: a phytochemical; an organic acid; and an antimicrobial peptide. In some embodiments, a composition as described herein can include a yeast component present in an amount of at least about 0.5% w/w of the composition; caffeine present in an amount of about 0.05% to about 5% w/w of the composition; a lemon grass extract present in an amount of at least about 0.01% to about 5% w/w of the composition; and an citrus fruit extract present in an amount of at least about 0.01% to about 5% w/w of the composition. In some embodiments, the composition further comprises a dermatologically acceptable carrier. Such compositions are useful for reducing body odor.
Patent WO-2020263883-A1 (WO)
Title: Endonuclease-resistant messenger rna and uses thereof
Inventor: BICKNELL ALICIA
IPC: C12N15/11
Filed: 2020-06-24
Abstract: The present disclosure provides messenger RNAs (mRNAs) with alterations which provide increased endonuclease resistance to the mRNA and methods and uses thereof.
Patent WO-2022031298-A1 (WO)
Title: Progressive addition lens for myopia control and method of manufacturing the same
Inventor: SPRATT RAY
IPC: G02C7/06
Filed: 2020-08-07
Abstract: A progressive addition lens with simultaneous myopic defocus providing microlenses, including a power variation surface is provided. The power variation surface (23) provides at least a designated distance portion (1 ) located in an upper section of the progressive addition lens (19) adapted to distance vision, and a fitting cross (17); a designated near portion (3) located in a lower section of the progressive addition lens, the near portion (3) including a near reference point (7) having a near dioptric power adapted to near vision; and a designated intermediate corridor (9) extending between the designated distance portion (1) and the designated near portion (3); where a number of microlenses (13) is superimposed on a surface (23) of the progressive addition lens (19). Microlenses (13) are excluded from all areas of said surface (23) which are located below a notional line (15) that extends from nasal to temporal limits of the progressive addition lens (19) at a vertical coordinate (y) above the near reference point (7) where the value of the coordinate (y) lies in a range between 1.5 mm and 3 mm. In addition, a method of manufacturing a progressive addition lens (19) with simultaneous myopic defocus providing microlenses (13) is defined. The method includes the steps of: Providing a progressive addition lens (19) with a power variation surface, where the power variation surface (23) provides at least a designated distance portion (1) in the upper section of the progressive lens, a designated near portion (3) in a lower section of the progressive addition lens (19), and a designated intermediate corridor (9) extending between the designated distance portion (1) and the designated near portion (3). The distance portion (1) includes the distance reference point (5) and the fitting cross (17). The near portion (3) includes a near reference point (7). Superimposing a number of microlenses (13) on a surface (23) of the progressive addition lens (19), where superimposition of microlenses (13) is excluded from all areas of said surface (23) which are located below a notional line (15) that extends from nasal to temporal limits of the progressive addition lens (19) at a vertical coordinate (y) above the near reference point (7) where the value of the coordinate (y) lies in a range between 1.5 mm and 3 mm.
Patent WO-2022035428-A1 (WO)
Inventor: CARBUNE VICTOR
IPC: G10L15/22
Filed: 2020-08-12
Abstract: The present disclosure is directed to interactive voice navigation. In particular, a computing system can provide audio information including one or more navigation instructions to a user via a computing system associated with the user. The computing system can activate an audio sensor associated with the computing system. The computing system can collect, using the audio sensor, audio data associated with the user. The computing system can determine, based on the audio data, whether the audio data is associated with one or more navigation instructions. The computing system can, in accordance with a determination that the audio data is associated with one or more navigation instructions, determine a context-appropriate audio response. The computing system can provide the context-appropriate audio response to the user.
Patent WO-2021035072-A1 (WO)
Title: Security and identity verification for neuromodulation therapy implant device programming
Inventor: PEPIN BRIAN MARC
IPC: A61B5/11
Filed: 2020-08-20
Abstract: Methods and systems are provided for securing communications with a neuromodulation-therapy implant device. A first subject-specific encryption-key value may be loaded onto a neuromodulation-therapy implant device, the first subject-specific encryption-key value being configured to generate a signature that may be included in data packets transmitted by the implant device. The signature may be generated by generating a hash value of the data of the data packet and encrypting the hash value. A request may be received from a mobile device for a second subject-specific encryption-key value that is different than but corresponds to the first subject-specific encryption-key value. The second subject-specific encryption-key value may be retrieved from a data store upon authenticating the request. The second encryption-key value corresponding to the first subject-specific encryption-key value may be transmitted to the mobile device.
Patent WO-2021050717-A1 (WO)
Title: Immune cell sequencing methods
Inventor: VOLLMERS CHRISTOPHER
IPC: G16B30/00
Filed: 2020-09-10
Abstract: Provided are immune cell RNA sequencing methods. In some embodiments, the methods comprise producing a circularized DNA comprising a complementary DNA (cDNA) and a known heterologous sequence, wherein the cDNA is produced from an immune cell RNA. Such methods further comprise performing rolling circle amplification using the circularized DNA as template to produce a concatemer comprising repeating segments comprising the cDNA and the known heterologous sequence. Such methods further comprise sequencing the concatemer or fragments thereof. Also provided are methods comprising producing immune cell RNA sequencing reads using a R2C2 sequencing method, extracting HLA reads from the sequencing reads, and producing allele-specific HLA sequences from the extracted HLA reads. Also provided are computer-readable media, systems, compositions and kits that find use, e.g., in practicing the methods of the present disclosure.
Patent WO-2021055635-A1 (WO)
Title: Distributed ledger appliance and methods of use
Inventor: HARMS JONATHAN D
IPC: G06Q20/16
Filed: 2020-09-17
Abstract: Computerized apparatus using characterized devices such as memories for intensive computational applications such as blockchain processing. In one embodiment, the computerized apparatus comprises a computational appliance (e.g., stand-alone box, server blade, plug-in card, or mobile device) that includes characterized memory devices. These memory devices are associated with a range of performances over a range of operational parameters, and can be used in conjunction with a solution density function to optimize memory searching. In one embodiment, the ledger appliance can communicate with other ledger appliances to create and/or use a blockchain ledger so as to facilitate decentralized exchanges between untrusted parties. In some variants, the ledger appliance may additionally use an application programming interface (API) to dynamically generate blockchains on the fly. Various other applications are also described (e.g., social media, machine learning, probabilistic applications and other error-tolerant applications).
Patent WO-2021055839-A1 (WO)
Title: Integrated transmission line installation system
Inventor: RADICHEL BRADLEY
IPC: H02G9/06
Filed: 2020-09-18
Abstract: An integrated transmission line installation system includes a transmission line conveying system that operates to install a transmission line within a conduit by advancing the transmission line through the conduit. The conduit includes at least a first segment and a second segment. The segments are evaluated to determine a full route including the routes of the first and second segments, and an installation plan is generated based at least in part on the full route. The transmission line conveying system includes two or more transmission line conveying apparatuses, a first that controls the advancement of the transmission line through the first segment, and a second that controls the advancement of the transmission line through the second segment. The transmission line conveying system controls and synchronizes the operation of the transmission line conveying apparatuses according to the installation plan so that the transmission line can be continuously installed through the full length of the conduit in a single pass.
Patent WO-2021087008-A1 (WO)
Inventor: SHUKLA ANITA
IPC: C08J3/075
Filed: 2020-10-28
Abstract: The invention provides a "host-guest" supramolecular hydrogel. The hydrogel contains an AAm/NVP interpenetrating polymer network (IPN) with supramolecular cross-linkers assembled from β lactam/adamantane-containing guest molecule with host polymeric cyclodextrin (PCD). An advantage of this hydrogel is that because of the molecular association of polymeric cyclodextrin and adamantane, the supramolecular hydrogels self-heal without any external stimuli after the hydrogels are severed. The invention also provides methods of making the hydrogel, methods of making the synthesis intermediates, and methods of diagnosis or treatment of β-lactamase-containing bacteria.
Patent WO-2021127661-A1 (WO)
Title: Collapsible wheels and methods of making collapsible wheels
Inventor: SOLHEIM JOHN A
IPC: A63B55/60
Filed: 2020-12-21
Abstract: Embodiments of collapsible wheels and methods of making collapsible wheels are generally described herein. Other embodiments may be described and claimed.
Patent WO-2021138544-A1 (WO)
Title: Devices and methods for antibiotic susceptibility testing
Inventor: CIOPYK BRIAN
IPC: B29C45/00
Filed: 2020-12-31
Abstract: The disclosure relates generally to molecular diagnostic devices configured to amplifying a single nucleotide polymorphism (SNP) locus and discriminate between two or more allelic variants of the SNP, indicating presence or absence of a target allele. In some embodiments, the molecular diagnostic devices are capable of detecting, at point-of-care, SNPs associated with resistance or susceptibility to antibiotic treatment of organism infections. In other aspects, the disclosure provides methods of treatment for disease or disorders ( e.g.  organism infections) where treatment is guided by presence or absence of an allele at a SNP locus as determined by such molecular diagnostic devices.
Patent WO-2021141825-A1 (WO)
Title: Ultra-reliable low latency communications (urllc) support for wireless access
Inventor: GUNDAVELLI SRINATH
IPC: H04L45/16
Filed: 2020-12-31
Abstract: Low latency wireless communications may be provided. A client device may be authorized for a first association in response to the client device making a first concurrent association request that may include a first Media Access Control (MAC) address. In response to authorizing the client device for the first association, an Endpoint Identifier (EID) associated with the client device may be registered with a first Routing Locator (RLOC) in a map server, the first RLOC being associated with the first MAC address. The client device may then be authorized for a second association in response to the client device making a second concurrent association request that includes a second MAC address. In response to authorizing the client device for the second association, the EID associated with the client device may be registered with a second RLOC in the map server, the second RLOC being associated with the second MAC address.
Patent WO-2021051121-A1 (WO)
Title: Research study user interfaces
Inventor: CROWLEY MATTHEW W
IPC: G06F3/0481
Filed: 2020-07-15
Abstract: The present disclosure generally relates to techniques and user interfaces for interacting with research studies. In some embodiments, an electronic device displays a user interface that includes a task view with active tasks from multiple research studies. In some embodiments, an electronic device, while displaying a research study user interface, displays an indication of a problem that prevents enrollment in the research study when enrollment problem criteria are met. In some embodiments, an electronic device, while performing a hearing test, suspends the test and displays a restart affordance when the ambient noise level exceeds a threshold.
Patent WO-2021146249-A1 (WO)
Title: New nasal respiratory apparatus
Inventor: KANE DAVID M
IPC: A61M16/10
Filed: 2021-01-13
Abstract: A nasal respiratory apparatus comprising a compressible nasal dam is removably engaged with an air chamber to provide respiratory gas to a patient. The air chamber has a gas connection port, at least one nasal conduit, a nasal end tidal sample port, wherein the gas connection port is configured to receive an externally supplied gas via a gas supply tube and wherein the at least one nasal conduit in fluid communication with the gas connection port. The nasal dam has a least one nares port corresponding to the at least one nasal conduit of the air chamber, the nares port extending from an upper external surface of the nasal dam to a lower external surface of the nasal dam such that the upper external surface of the nasal dam interfaces with soft tissue of a patient's nasal base to provide a substantial seal around the patient's nasal base to facilitate respiratory gas supply to the patient.
Patent WO-2022169450-A1 (WO)
Title: Journalisation de persistance sur nvm express pour application de dispositifs d'enregistrement
Inventor: HU CHAOHONG
IPC: G06F12/02
Filed: 2021-02-04
Abstract: Un procédé de fonctionnement d'un système informatique (100) comprend la définition d'un espace de nom à zones d'une mémoire non volatile (NVM) d'un dispositif de mémoire (120) du système informatique, l'espace de nom à zones comprenant de multiples zones NVM de multiples adresses de blocs logiques ne se chevauchant pas (LBA) de la NVM ; le mappage d'identifiants (ID) de la journalisation de persistance (FLOG) aux zones de NVM, un ID de FLOG identifiant une zone de FLOG d'une ou de plusieurs zones de NVM ; et la réalisation d'un fonctionnement d'accès spécifique au PLOG sur une zone de FLOG de la NVM en réponse à une commande spécifique au PLOG reçue en provenance d'un dispositif hôte du système informatique.
Patent WO-2021159110-A1 (WO)
Title: Chuck assembly for a drill tool and drill bit member
Inventor: RUSSELL JOSEPH
IPC: B23B51/10
Filed: 2021-02-08
Abstract: A central chuck including a chuck base, a first chuck and a first drill bit. The first chuck is rotatably coupled to the chuck base and has a chuck bore terminating at a lower chuck wall and a transverse locking bore. A locking plug is threaded into the transverse locking bore. The first drill bit has an upper portion, a central portion and a distal end. The upper portion has a smaller diameter than the central portion with a shoulder spanning between the upper portion and the central portion. An oblique plane defined in the upper portion inclined in a downward and inward direction toward the shoulder. Threaded insertion of the locking plug into the chuck bore interfaces with the drill bit and directs the drill bit in an upward direction and forces the shoulder into tight abutment with the lower chuck wall.
Patent WO-2021173600-A1 (WO)
Inventor: FIX ANDREW
IPC: B01D53/18
Filed: 2021-02-24
Abstract: A heat exchange system is disclosed which includes an air inlet, a membrane in fluid communication with the air inlet and adapted to have a partial vapor pressure difference across the membrane to thereby drive water vapor flux through the membrane, wherein the membrane is a selective membrane configured to allow passage of water vapor and block passage of air (O 2 /N 2 ) through the membrane, where the membrane includes a thermally conductive side, a vacuum pump configured to generate the partial vapor pressure difference across the membrane, and a heat exchanger coupled to the thermally conductive side of the membrane configured to provide simultaneous mass and heat transfer.
Patent WO-2021194944-A1 (WO)
Inventor: TRIKHA NITESH
IPC: G08B25/10
Filed: 2021-03-22
Abstract: Disclosed herein as methods, apparatuses, non-transitory computer readable media, and systems relating to reduction and/or identification of one or more health risks in a facility. For example, by sensing a bodily characteristic of an individual in a facility, e.g., by sensing at least one environmental characteristic. For example, by sensing surface cleanliness. For example, by tracking personnel in the facility. For example, by suggesting routes in an enclosure based at least in part in personnel concentration in the facility. Disclosed herein as methods, apparatuses, non- transitory computer readable media, and systems relating to monitoring occupancy of a facility.
Patent WO-2021195091-A1 (WO)
Title: Ensemble électrode comprenant des émetteurs plaqués
Inventor: MODA SUNIL
IPC: A61B90/00
Filed: 2021-03-23
Abstract: L'invention concerne un ensemble électrode qui comprend un corps allongé, un émetteur proximal et un émetteur distal. Un orifice d'évacuation peut être en communication fluidique avec une lumière du corps allongé. Les émetteurs proximal et distal sont formés par placage métallique d'une surface externe du corps allongé qui est un polymère. Une partie du corps allongé forme un espaceur isolant entre les émetteurs proximal et distal. Un capuchon distal peut être accouplé au corps allongé, formé à partir d'un matériau conducteur et agencé en communication électrique avec l'émetteur distal. Un fil distal, un thermocouple et/ou un hypotube peuvent être disposés à l'intérieur de la lumière pour former un trajet électrique avec le capuchon distal. Une gaine peut être disposée sur une partie de l'émetteur proximal et un marqueur radio-opaque peut être accouplé à l'émetteur proximal. L'invention divulgue également des procédés de fabrication de l'ensemble électrode.