baber/WOPTO huggingface dataset:
Patent CA-3074799-A1 (CA)
Inventor: DURACK GARY
IPC: C12Q1/04
Filed: 2004-03-29
Abstract: Il est décrit un procédé permettant dévaluer un ensemble de conditions pour colorer une population de cellules servant au tri, la population comprenant un premier et un second type de cellule, le procédé consistant à : (a) colorer des cellules avec une coloration fluorescente sous un ensemble de conditions de coloration; (b) exposer les cellules colorées à un rayonnement électromagnétique à mesure que les cellules passent par un emplacement dinterrogation dun cytomètre de flux à un débit, R; (c) déterminer une caractéristique démission de fluorescence des cellules exposées; (d) utiliser la caractéristique en question pour classifier les cellules en sous-populations de cellules, y compris une sous-population enrichie du premier type de cellule; (e) déterminer un coefficient de variation pour la caractéristique démission de fluorescence des cellules de la sous-population enrichie pour donner une indication de lefficacité de tri pour les conditions de coloration; et (f) déterminer sil convient de modifier toute condition de coloration ou le débit, R, au cours duquel les cellules traversent lemplacement dinterrogation afin daméliorer lefficacité de tri.
Patent CA-3074940-A1 (CA)
Inventor: MITCHELL DAVID JOHN
IPC: G01S1/70
Filed: 2018-09-06
Abstract: A headset for use in displaying a virtual image of a building information model (BIM) in relation to a site coordinate system of a construction site. The headset comprises an article of headwear having one or more position-tracking sensors mounted thereon, augmented reality glasses incorporating at least one display, a display position tracking device for tracking movement of the display relative to at least one of the user's eyes and an electronic control system. The electronic control system is configured to convert a BIM model defined in an extrinsic, real world coordinate system into an intrinsic coordinate system defined by a position tracking system, receive display position data from the display position device and headset tracking data from a headset tracking system and render a virtual image of the BIM relative to the position and orientation of the article of headwear on the construction site and relative position of the display relative to the user's eye and transmit the rendered virtual image to the display which is viewable by the user as a virtual image of the BIM.
Patent CA-3077058-A1 (CA)
Inventor: MALI VISHAAL
IPC: H02J3/32
Filed: 2018-10-01
Abstract: Cette invention concerne un système de gestion de puissance, comprenant un circuit convertisseur de puissance, une unité de stockage à supercondensateur, et un contrôleur de partage de charge en communication avec le circuit convertisseur de puissance et l'unité de stockage à supercondensateur. En réponse à l'exécution des instructions de programme, le contrôleur de partage de charge est configuré pour recevoir des données comprenant la demande de puissance provenant du dispositif externe, recevoir des données comprenant la puissance brute provenant du circuit convertisseur de puissance, recevoir des données comprenant une capacité provenant de l'unité de stockage à supercondensateur, et diriger la puissance vers le dispositif externe sur la base des données reçues.
Patent CA-3077175-A1 (CA)
Inventor: DEL BONO MARIA CRISTINA
IPC: A23L33/125
Filed: 2018-10-11
Abstract: Combination of dry extract of Rhodiola, dry extract of Tribulus terrestris, dry extract of Undaria pinnatifida, Moringa oleifera, folic acid and vitamin B12 in the form of food supplement for mitigating woman's disorders caused by ageing.
Patent CA-3081114-A1 (CA)
Title: Integrity protection control method, network device and computer storage medium
Inventor: YANG NING
IPC: H04W12/106
Filed: 2017-11-08
Abstract: Disclosed in the present invention are an integrity protection control method, a network device and computer storage medium, the method comprising: acquiring parameter configuration information, wherein the parameter configuration information is parameter configuration information saved by a network device or parameter configuration information acquired from a core network side; and on the basis of the parameter configuration information, determining whether it is necessary to start integrity protection for a quality of service (QoS) data flow.
Patent CA-3084692-A1 (CA)
Inventor: MURRAY CHRIS I
IPC: G16H50/20
Filed: 2018-10-16
Abstract: Methods and apparatus for predicting performance of an individual on a task, the method comprises receiving brain imaging data for the individual, wherein the brain imaging data comprises structural brain data, determining values for at least one characteristic of the structural brain data within regions of interest defined for a population of individuals having different performance levels, and predicting based on the determined values, a performance potential of the individual.
Patent CA-3087769-A1 (CA)
Inventor: HUNTER CHARLES ERIC
IPC: A61M15/00
Filed: 2019-01-08
Abstract: Methods for the treatment of pulmonary cancers (primary, secondary, metastatic, etc.) using an electronic breath actuated droplet delivery device to deliver a cancer therapeutic directly to the pulmonary system of a subject in need thereof is disclosed. An in-line droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The in-line droplet delivery device includes a housing, an ejector mechanism, and at least one differential pressure sensor. The in-line droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The in-line droplet delivery device is then actuated to generate a plume of droplets having an average ejected particle diameter within the respirable size range, e.g, less than about 5-6 µm, so as to target the pulmonary system of the user.
Patent CA-3091310-A1 (CA)
Inventor: PLOCKL MANFRED
IPC: B25H1/00
Filed: 2019-03-08
Abstract: The invention relates to an exchangeable milling adapter (20) for a workbench (60) which comprises a receptacle (21) for a milling cutter (70) and an angle adjuster (22). An angular position (WP1, WP2) of the receptacle (21) in relation to the workbench is adjustable using the angle adjuster (22). The invention also relates to a workbench, a milling unit and the use thereof for adjusting a milling cutter.
Patent CA-3093581-A1 (CA)
Inventor: ALLBRITTON NANCY L
IPC: C12N13/00
Filed: 2019-05-15
Abstract: Disclosed herein are devices, apparatuses and methods for generating self-sustaining gaseous and non-gaseous gradients across a cell support structure and for culturing one or more cells or tissues under hypoxic conditions. Methods of generating one or more gas gradients across a cell support structure include providing a luminal container having a bottom wall that is a gas permeable membrane, positioning a cell support structure above the bottom wall, positioning one or more cells or tissues on the cell support structure, and generating one or more gas gradients between the bottom wall, across the cell support structure and into a luminal reservoir. An apparatus to produce hypoxic conditions for cell cultures includes a luminal container having a bottom wall, a cell support structure on the bottom wall, and a cover that sealably closes the open top, such that a hypoxic condition can be generated in the luminal reservoir.
Patent CA-3094061-A1 (CA)
Title: Fermeture de recipient a attache
Inventor: CASZATT BRADLEY W
IPC: B65D41/34
Filed: 2018-03-15
Abstract: L'invention concerne une fermeture destinée à fermer une ouverture délimitée par une finition d'un récipient. La fermeture comprend un corps principal et une bande d'inviolabilité. La bande d'inviolabilité est reliée au corps principal par une pluralité de ponts. Une charnière de la fermeture est conçue pour permettre au corps principal de pivoter par rapport à la bande d'inviolabilité.
Patent CA-3095166-A1 (CA)
Title: Synthetic signaling constructs and its use
Inventor: SCHNEIDER ARTUR
IPC: A61K38/17
Filed: 2019-04-08
Abstract: In a first aspect, the present invention relates to new recombinant artificial polypeptides allowing cytoplasmic signaling in cells containing the same. In particular, the present invention relates to a system for transmitting signals containing a recombinant polypeptide containing a domain with a first binding partner selected from an artificial ligand and a receptor binding an artificial ligand, a transmembrane domain and a cytoplasmic signaling domain whereby the domain with the binding partner and the cytoplasmic signaling domain are a combination of domains not naturally occurring in an organism and the second binding partner for specific forming of the binding pair. In a further aspect, a nucleic acid molecule comprising a nucleic acid sequence encoding the polypeptide according to the present invention as well as a vector, cell, cell line or host cell containing said vector are provided. In addition, the present invention relates to the use of the recombinant polypeptide according to the present invention in treating cancer or autoimmune disease or allowing immune modulation of a subject as well as for use to change the status of cells when applying the specific second binding partner of the first binding partner present in the recombinant polypeptide according to the present invention.
Patent CA-3095810-A1 (CA)
Inventor: JESSUP COLE J
IPC: F41B5/12
Filed: 2020-10-08
Abstract: An anti-dry-fire mechanism for a crossbow includes a slotted mainframe and a movable trigger subassembly engaged with the slot for bidirectional movement between brace and drawn positions. The movable subassembly includes a bowstring latch forward of a bowstring catch and biased toward a bolt-absent position in which the bowstring latch obstructs forward movement of the bowstring past the bowstring latch;  in its bolt-present position the bowstring latch permits such movement. With the movable subassembly in the drawn position, a bolt loaded onto the mainframe holds the bowstring latch in its bolt-present position against its bias; with the movable subassembly in the drawn position and no bolt loaded, the bowstring latch is held in its bolt-absent position by its bias. With the movable subassembly in the brace position, engagement of the mainframe and bowstring latch holds the bowstring latch in its bolt-present position against its bias.
Patent CA-3096293-A1 (CA)
Inventor: KERAVALA ANNAHITA
IPC: C12N15/63
Filed: 2019-04-29
Abstract: La présente invention concerne d'une manière générale des compositions et des méthodes pour traiter, prévenir, inhiber ou retarder la dégénérescence du système nerveux central. L'invention concerne un vecteur recombiné de thérapie génique comprenant un gène PARK2, PINK1, DJ-1, LRRK2, SCNA, c-Rel, ATG7, VMAT2, ou GBA ou un fragment fonctionnel ou un variant de celui-ci. L'invention concerne également des systèmes d'édition de gènes basés sur CRISPR/Cas pour traiter, prévenir, inhiber ou retarder la dégénérescence du système nerveux central.
Patent CA-3097326-A1 (CA)
Title: Ethylene-vinyl alcohol copolymer, method for producing same, and use thereof
Inventor: TANIDA TATSUYA
IPC: C08F8/12
Filed: 2019-04-16
Abstract: An ethylene-vinyl alcohol copolymer having a content of ethylene units of 1 to less than 20 mol%, a viscosity average degree of polymerization of 200-5000, and a degree of saponification of 80-99.7 mol%, wherein the ethylene-vinyl alcohol copolymer has an ethylene unit block character of 0.90-0.99 in the ethylene-vinyl alcohol copolymer. Such an ethylene-vinyl alcohol copolymer has excellent high-speed coating property and water-resistant adhesiveness when used as an adhesive in particular.
Patent CA-3100280-A1 (CA)
Title: Aav cardiac gene therapy for cardiomyopathy
Inventor: SWEENEY HUGH LEE
IPC: C12N15/864
Filed: 2019-06-07
Abstract: The present invention is related to compositions and methods useful in treating heart conditions. The disclosed compositions and methods are based on an AAV therapy comprising a recombinant AAV vector for delivering two or more transgenes into the heart of a subject, wherein the transgenes comprise an S100 family protein and an apoptotic inhibitor. In some aspects, targeting multiple sources of one or more heart conditions can provide synergistic benefits during treatment.
Patent CA-3100762-A1 (CA)
Inventor: ZHANG ZHIYI
IPC: H01L27/146
Filed: 2019-05-14
Abstract: Methods are provided for fabricating photodetector arrays using passive matrix addressing technology. The photodetector arrays use a pair of switching diode and photo diode to overcome crosstalk issues within the passive matrix. The switching diode and the photo diode of each pixel may be connected using a cathode-to-cathode connection, or an anode-to-anode connection. The photodetector arrays are fabricated by assembling on a first substrate, an array of photodetector pixels comprising a switching diode and a photo diode, providing conductive lines for each row of the array and conductive lines for each column of the array, and attaching a second substrate to the first substrate. The photodetector array may also be fabricated by assembling on a first substrate an array of switching diodes, and assembling on a second substrate an array of photo diodes, and bonding the first and second substrates together.
Patent CA-3101028-A1 (CA)
Title: Compositions and methods of muscle specific kinase chimeric autoantibody receptor cells
Inventor: PAYNE AIMEE S
IPC: A61K35/12
Filed: 2019-06-04
Abstract: The invention includes a chimeric autoantibody receptor (CAAR) specific for anti-muscle-specific kinase (MuSK) B cell receptor (BCR), compositions comprising the CAAR, polynucleotides encoding the CAAR, vectors comprising a polynucleotide encoding the CAAR, and recombinant cells comprising the CAAR.
Patent CA-3101531-A1 (CA)
Title: System and method for testing engine performance in-flight
Inventor: DROLET MARTIN
IPC: B64D31/00
Filed: 2020-12-03
Abstract: ABSTRACT  Systems and Methods are described for testing engine performance in-flight in an aircraft having a first engine and a second engine. The method comprises operating the first engine at a first power level in an output speed governing mode, operating the second engine at a second power level greater than the first power level in a core speed governing mode concurrently with the first engine operating at the first power level in the output speed governing mode, and performing an engine performance test on the second engine while the second engine is at the second power level in the core speed governing mode. Date Recue/Date Received 2020-12-03
Patent CA-3104353-A1 (CA)
Inventor: SHEN TAO
IPC: G06F3/06
Filed: 2018-12-12
Abstract: Disclosed are a storage volume creation method and apparatus, a server, and a storage medium. The method comprises: obtaining the attribute information of a storage volume to be created, and the information of a joint storage pool used for creating the storage volume to be created; selecting a target sub storage pool in the joint storage pool corresponding to the information of the joint storage pool, wherein the joint storage pool comprises at least one sub storage pool; and according to the attribute information of the storage volume to be created, creating the storage volume in the target sub storage pool by means of a physical storage medium therein.
Patent CA-3105042-A1 (CA)
Inventor: EBETINO FRANK HALLOCK
IPC: A61P19/08
Filed: 2019-06-25
Abstract: L'invention concerne des composés d'oxazolidinone bisphosphonate, et leurs conjugués et formulations pharmaceutiques, qui peuvent comprendre un bisphosphonate et une oxazolidinone (ou un agent antimicrobien ou antibiotique d'oxazolidinone, son substituant ou son dérivé), l'oxazolidinone pouvant être couplée de manière amovible au bisphosphonate. L'invention concerne également des procédés de fabrication et des procédés d'utilisation des composés de d'oxazolidinone bisphosphonate, de leurs conjugués et formulations pharmaceutiques. L'invention concerne également des procédés d'utilisation des composés, des conjugués et des formulations pour le traitement d'une maladie osseuse ou pour une utilisation dans la préparation d'une formulation pour le traitement d'une maladie osseuse.
Patent CA-3109537-A1 (CA)
Title: Two-component inorganic injection mortar system based on fine aluminous cement having increased load values
Inventor: PFEIL ARMIN
IPC: C04B14/28
Filed: 2019-10-02
Abstract: The present invention pertains to a two-component inorganic injection mortar system comprising a curable aqueous-phase aluminous cement component A and an initiator component B in aqueous-phase for initiating the curing process, component A further comprising at least one blocking agent selected from the group consisting of phosphoric acid, metaphosphoric acid, phosphorous acid and phosphonic acids, at least one plasticizer and water, and component B comprising an initiator, at least one retarder, at least one mineral filler and water, characterized in that the curable aqueous-phase aluminous cement component A comprises calcium aluminate cement having an average particle size in the range of from 0.5 to 15 µm. Moreover, the present invention pertains to a two-component system, which is ready-for-use, for chemical fastening of anchoring means, preferably of metal elements, in mineral substrates, such as structures made of brickwork, concrete, pervious concrete or natural stone as well as its use for chemical fastening of anchoring means.
Patent CA-3110426-A1 (CA)
Title: Compose bioactif
Inventor: NORTHCOTE PETER THOMAS
IPC: C07D307/93
Filed: 2019-08-28
Abstract: L'invention concerne un nouveau sesquiterpène contenant du furane, la structure étant représentée par la formule (X). Le nouveau sesquiterpène contenant du furane peut être obtenu à partir de l'écorce de l'arbre Melicope latifolia à une concentration relativement élevée et s'est avéré avoir des propriétés antibiotiques.
Patent CA-3113836-A1 (CA)
Title: Stain removing oral care compositions comprising medium length polyphosphates
Inventor: RAMJI NIRANJAN
IPC: A61K8/24
Filed: 2019-11-07
Abstract: Described herein are oral care compositions with improved stain removal performance without having to increase the amount of abrasive or incorporating oxidizing agents.  For example, an oral care composition comprises: (a) about 20 % or greater, by weight of the oral care composition, of water; (b) a polyphosphate source comprising: (i) a first linear polyphosphate with an average chain length of from about 6 to about 21; (ii) a second linear polyphosphate with an average chain length of from about 2 to about 6, wherein the second linear polyphosphate has a smaller chain length than the first linear polyphosphate; (c) a pH of about 5 or less, and wherein the composition has a AE of about 3 or less.
Patent CA-3116066-A1 (CA)
Title: Dispositif d'embolisation et ses spires de ressort
Inventor: Guo yuanyi
IPC: A61B17/12
Filed: 2019-10-08
Abstract: La présente invention concerne un dispositif d'embolisation et ses spires de ressort (10, 20, 30). Chacune des spires de ressort (10, 20, 30) est formée par liaison à au moins quatre unités de base dans différents plans, lesdites quatre unités de base comprenant au moins deux unités en forme de C (12) et au moins une unité en forme de O (13) ou une unité en forme d'O (11), et lesdites deux unités en forme de C (12) sont disposées en deux plans adjacents et sont séquentiellement reliées en vue de former une structure en forme de S. Le dispositif d'embolisation comprend préférablement une pluralité de spires de ressort (10, 20, 30) disposées côte-à-côte, la pluralité des spires de ressort (10, 20, 30) étant reliées bout-à-bout, et l'une de deux spires de ressort (10, 20, 30) adjacentes quelconques, peut être torsadée autour de l'axe du dispositif d'embolisation par rapport à l'autre. En raison d'une bonne stabilité de la structure en forme d'O, la stabilité des spires de ressort (10, 20, 30) peut être conservée. En même temps, en raison d'une bonne capacité de torsion de la structure tridimensionnelle en forme de S, les spires de ressort (10, 20, 30) présentent une bonne adaptabilité. Conçues de cette manière, les spires de ressort (10, 20, 30) peuvent satisfaire les exigences d'encadrement stable et de remplissage uniforme en même temps, de sorte que ceci permet aux spires de ressort (10, 20, 30) de s'adapter aux anévrismes de différentes formes et tailles, et par conséquent, un bon effet de remplissage compact est obtenu.
Patent CA-3116640-A1 (CA)
Title: Component mixing device and component mixing method
Inventor: MARINE JULIEN
IPC: A61K38/00
Filed: 2018-11-23
Abstract: The present invention relates to a component mixing device comprising a central unit (10) and a disposable cartridge, said central unit (10) comprising a control unit, a plurality of vial positioning elements (13) and a cavity (14) for receiving the disposable cartridge, said disposable cartridge (20) comprising a microfluidic circuit suitable for placing the components received in the plurality of vials in communication with each other for the purpose of mixing, characterised in that the mixing device is suitable for placing the bottles in communication with each other by way of the microfluidic circuit of the disposable cartridge (20) and for mixing said components by means of a compressed air mechanism (12) located in the central unit (10) and controlled by the control unit.
Patent CA-3117778-A1 (CA)
Title: Freezer case with variable superheat setpoints
Inventor: KAEMINGK NATE
IPC: F25D29/00
Filed: 2021-05-07
Abstract: A freezer case includes a refrigeration system and a controller. The controller is configured to store a plurality of setpoint instruction sets associated with a plurality of possible operating modes, select a current operating mode from the plurality of possible operating modes, assign a value for the superheat setpoint by executing the setpoint instruction set associated with the current operating mode, control the refrigeration system in accordance with the superheat setpoint.
Patent CA-3120326-A1 (CA)
Inventor: TAL MICHAEL GABRIEL
IPC: A61B17/12
Filed: 2019-12-02
Abstract: La présente invention concerne un appareil et un procédé pour former un passage s'étendant le long d'un plan croisant une région volumétrique d'organe d'un point d'entrée à un point de sortie opposé au niveau d'une surface de l'organe, et pour faire passer un élément de tension autour de la région volumétrique en tirant l'élément de tension du point de sortie au point d'entrée à travers le passage. L'appareil peut comprendre un tube externe rigide avec un embout pour pénétrer dans l'organe et atteindre une profondeur de pénétration ; une aiguille interne avec un corps élastique configuré pour traverser de façon rectiligne la lumière du tube externe et pour faire partiellement saillie et fléchir volontairement jusqu'à une forme incurvée plus grande que le diamètre de la région volumétrique ; et un dispositif de passage d'élément de tension avec une partie de traction pour venir en prise avec une partie de l'élément de tension et pour tirer l'élément de tension lorsqu'il est retiré.
Patent CA-3123045-A1 (CA)
Title: Donor t-cells with kill switch
Inventor: YAN MING
IPC: C12N15/87
Filed: 2019-12-23
Abstract: The disclosed methods are generally directed to preventing, treating, suppressing, controlling or otherwise mitigating side effects of T-cell therapy, the T-cell therapy designed to accelerate immune reconstitution, induce a graft-versus-malignancy effect, and/or target tumor cells. In some embodiments, the present disclosure provides expression vectors including a first expression control sequence operably linked to a first nucleic acid sequence, the first nucleic acid sequence encoding a shRNA to knockdown hypoxanthine-guanine phosphoribosyl transferase.