baber/WOPTO huggingface dataset:
Patent AT-E271890-T1 (AT)
Inventor: FELL CLAUDE
IPC: A61J3/00
Filed: 1999-12-24
Granted: 2004-08-15
Abstract: A system for separating biological fluids into components, comprises a set of containers for the biological fluid to be separated and the separated components, optionally an additional container for additive solution, and a hollow centrifugal processing chamber having an axial inlet/outlet for the biological fluid. The processing chamber contains a piston movable to intake a selected quantity of biological fluid and express processed biological fluid components via the outlet. Optical means monitor the position of piston to control the amount of intaken fluid and the expression of components. A distribution valve arrangement selectively communicates the processing chamber and the containers or places them out of communication. The system is arranged to operate in a seperation mode and in a non-separation transfer mode, especially for adding preservative solution to separated blood stem cells.
Patent AT-E346865-T1 (AT)
Inventor: MATHER JENNIE P
IPC: G01N33/48
Filed: 1999-12-22
Granted: 2006-12-15
Abstract: The present invention provides a method for generating a population of monoclonal antibodies capable of binding to antigens representative of a particular cell type. The method is unique in that it minimizes the generation of non-representative antibodies cross-reacting with proteins not present in a particular cell type; it also maximizes the preservation of intact antigens, especially surface antigens, for production of a plurality of monoclonal antibodies that bind to the native antigens. The present invention also includes a method of determining the combination of cell surface antigens present on a specific cell type. Further provided by the invention are hybridomas, populations of monoclonal antibodies produced by the hybridomas of the present invention.
Patent AT-E299327-T1 (AT)
Inventor: CARPENTER J WILTSE
IPC: H04L12/24
Filed: 1999-11-30
Granted: 2005-07-15
Abstract: A video on demand system includes a head-end coupled through a proxy server to plural client terminals. The proxy server performs (or cooperates with another component in performing) various functions, including user interface definition, security, system administration (e.g. channel management, load distribution, and failover), and protocol translation. <IMAGE>
Patent AT-E381321-T1 (AT)
Inventor: WATANABE YASUSHI
IPC: A61K9/28
Filed: 1999-10-05
Granted: 2008-01-15
Abstract: A tablet including active substance affected by lubricant, wherein the tablet is comprised of compressed mixture of active substance and adjuvant except for lubricant, and lubricant exists only on the surface of the tablet but is not included in the tablet. Such a tablet production method comprising the steps of producing mixture of active substance affected by lubricant and adjuvant, mixing lubricant powder with positive pulsating vibration air for dispersion, spraying the lubricant powder dispersed by the positive vibration air on a lower surface of an upper punch, an upper surface of a lower punch and an inner circumferential wall of a die, and tabletting the mixture by means of the upper and lower punches and the die.
Patent DE-16816608-T1 (DE)
Title: Fester bremssattel einer scheibenbremse mit integriertem elektrischem aktuator
Inventor: PASQUET THIERRY
IPC: F16D55/16
Filed: 2016-12-08
Abstract: Fester Bremssattel (2, 2') einer Scheibenbremse mit mindestens einem Paar (11) gegenüber liegender Bremskolben (114, 124), umfassend einen ersten Kolben und einen zweiten Kolben, welche in zwei zusammengefügten Halbgehäusen (21, 22) aufgenommen sind, wobei die Kolben zum Beaufschlagen und Klemmen von mindestens einem Paar Reibbelägen (92, 93) auf Reibbahnen einer Bremsscheibe (91) eingerichtet sind, dadurch gekennzeichnet, dass er umfasst: mindestens einen Antriebsmechanismus, welcher einen Motor oder Getriebemotor (6) enthält, der zum drehbeweglichen Antrieb eines ersten, mit dem ersten Kolben koaxial gelagerten Schrauben-Mutter-Mechanismus derart eingerichtet ist, um eine lineare Verschiebung des ersten Kolbens längs dessen Achse in einer ersten Richtung herbeizuführen, und mindestens einen mechanischen Übertragungsmechanismus, der zwischen den beiden Halbgehäusen (21, 22) verteilt und zur Zusammenwirkung mit dem Antriebsmechanismus derart eingerichtet ist, um einen zweiten, mit dem zweiten Kolben koaxial gelagerten Schrauben-Mutter-Mechanismus derart drehbeweglich anzutreiben, um eine lineare Verschiebung des zweiten Kolbens längs dessen Achse in einer zweiten Richtung entgegen der ersten Richtung herbeizuführen.
Patent DE-17817632-T1 (DE)
Title: Melaminoctamolybdat mit hoher thermischer stabilität und verwendung davon als rauchunterdrücker in polymerzusammensetzungen
Inventor: LIU YUE
IPC: D01F1/07
Filed: 2017-12-07
Abstract: Ein Verfahren zum Herstellen von Melaminoctamolybdat, wobei das Verfahren das Umsetzen von Molybdäntrioxid (MoO) und Melamin in einem sauren wässrigen System bei einem pH-Wert von weniger als oder gleich ungefähr 4 beinhaltet, um eine Aufschlämmung des Melaminoctamolybdats zu bilden; wobei:das Melaminoctamolybdat durch eine Temperatur bei einem Gewichtsverlust von 1 % auf einer Kurve einer thermogravimetrischen Analyse in einem Bereich von ungefähr 300 °C bis ungefähr 500 °C gekennzeichnet ist; und/oderdas Melaminoctamolybdat durch eine Temperatur bei einem Gewichtsverlust von 2 % auf einer Kurve einer thermogravimetrischen Analyse in einem Bereich von ungefähr 300 °C bis ungefähr 500 °C gekennzeichnet ist.
Patent DE-106141-T1 (DE)
IPC: C08F10/00
Filed: 1983-09-09
Abstract: Catalyst components for the stereoregular polymerization of alpha-olefins, comprising a Ti halide and an electron-donor compound supported on an anhydrous magnesium dihalide and obtained by means of non-extractive treatments, with liquids having a dielectric constant at 20 DEG  C. equal to or higher than 2, of compositions comprising an anhydrous Mg dihalide, the crystallites of which have an average size lower than 300  ANGSTROM . The present invention refers to new catalyst components and the catalysts obtained therefrom for the polymerization of alpha-olefins Ch2=CHR, wherein R is an alkyl radical with 1-4 C atoms or an aryl radical, and of mixtures of said alpha-olefins with minor amounts of ethylene.
Patent DE-517635-T1 (DE)
IPC: D01G15/98
Filed: 1992-06-05
Abstract: The present invention concerns a wool card applicable in the field of the textile industry. The card is characterized in that it is equipped with at least three Morel rollers (1), in that it does not have an intermediate comb and in that the tangential velocities of the feeder rollers (2) and the large drum (3) are equal, the reduction in speed of the fiber web between the large drum (3) and the following Morel roller (1) being relatively low.
Patent ES-2693318-T1 (ES)
Title: Lámina y procedimiento para producir dicha lámina
Inventor: HEINRICH MATTHIAS
IPC: G06F3/041
Filed: 2016-11-21
Abstract: Lámina (1) que comprende un sustrato portador (2), una capa de adhesión (4) para la aplicación de la lámina (1) sobre un sustrato-objetivo (10) y al menos una capa eléctricamente conductora (3), en la que al menos una capa eléctricamente conductora (3), en un área de funcionamiento (21), conforma una estructura de funcionamiento eléctrica, en la que al menos una capa eléctricamente conductora (3), en al menos un área de puesta en contacto (20), conforma al menos una estructura de puesta en contacto para la puesta en contacto de la estructura de funcionamiento eléctrica, y en la que la capa de adhesión (4), en el caso de una observación perpendicularmente con respecto un plano extendido desde el sustrato portador (2), no recubre al menos en algunas secciones al menos un área de puesta en contacto (20), o en la que la capa de adhesión (4), en el caso de una observación perpendicularmente con respecto a un plano extendido desde el sustrato portador (2), está aplicada en toda la superficie.
Patent ES-2086272-T1 (ES)
Title: Procedimiento de blanqueo de pasta de papel mediante ozono.
Inventor: COSTE CHRISTIAN
IPC: D21C9/10
Filed: 1994-07-20
Abstract: PROCESO DE BLANQUEAMIENTO DE PASTA DE PAPEL CRUDA DE TIPO QUIMICO MEDIANTE OZONO CARACTERIZADO EN QUE NO APLICA MAS QUE UN ESTADIO DE OZONO EXCLUSIVAMENTE, EN PRESENCIA DE UN ALCOHOL TERCIARIO, QUE COMPRENDE DE CUATRO A OCHO ATOMOS DE CARBONO QUE ESTA INTRODUCIDO EN EL MEDIO DE REACCION MANTENIDO A UNA TEMPERATURA COMPRENDIDA ENTRE -5 (GRADOS) C Y 80 (GRADOS) C, PREVIAMENTE AL ESTADIO DE LA OZONIZACION PROPIAMENTE DICHO. CON EL FIN DE MEJORAR LA TRANSFERENCIA GAS-LIQUIDO, LA POTENICALIDAD DE INTERCAMBIO, LA SELECTIVIDAD DE LA OXIDACION DE LA LIGNINA Y LA EFICACIA DEL OZONO, LA CONSISTENCIA DE LA PASTA SOMETIDA A LA OZONIZACION QUE ESTA COMPRENDIDA ENTRE 6 Y 60%.
Patent ES-2106001-T1 (ES)
Title: Dispositivo para recibir, fijar, sujetar, centrar uno o varios objetos de uso corriente.
Inventor: WELP KARL GISBERT
IPC: A47L13/512
Filed: 1996-12-13
Abstract: EL DISPOSITIVO DE ACUERDO CON LA INVENCION PARA LA RECEPCION, FIJACION, SOPORTE, CENTRADO DE UNO O MULTIPLES OBJETOS DE UTILIZACION, EN PARTICULAR APARATOS DE ESCRITURA, APARATOS DE AFEITADO, APARATOS DE ESCUCHA, JOYAS, RELOJES, MEDALLAS, SE CARACTERIZA DE TAL MODO, QUE - MUESTRA UNA PLACA (1) BASICA A BASE DE UN PRIMER MATERIAL CON AL MENOS DOS ELEMENTOS (2) DE TORSION Y/O REFUERZO SOBRE LA BASE DE UN SEGUNDO MATERIAL, FORMANDOSE CON ELLO UN CUERPO (3) BASICO, DONDE EL PRIMER MATERIAL Y EL SEGUNDO MATERIAL PUEDEN SER LO MISMO, - EL CUERPO (3) BASICO ESTA UNIDO A TRAVES DE LOS ELEMENTOS (2) DE TORSION Y/O DE REFUERZO CONOCIDOS CON UN CUERPO (4) DE RECEPCION A BASE DE MATERIAL SINTETICO TERMOPLASTICO O CAUCHO SEGUN UNA APLICACION MECANICA Y/O QUIMICA AL MENOS SOBRE UN LADO DEL CUERPO (3) BASICO, DE TAL MODO QUE ES POSIBLE UNA SEPARACION ENTRE EL CUERPO (3) BASICO CONOCIDO Y EL CUERPO (4) DE RECEPCION INDICADO SOLO BAJO DESTRUCCION AL MENOS PARCIALMENTE DE UNO DE AMBOS CUERPOS (3,4), Y - EL CUERPO (4) DE RECEPCION INDICADO MUESTRA BRAZOS (5) PARA LA RECEPCION, FIJACION, SOPORTE, CENTRADO DE LOS OBJETOS DE UTILIZACION INDICADOS.
Patent ES-2131493-T1 (ES)
Title: Perfeccionamientos introducidos en los hornos de enfriamiento rapido para cintas metalicas.
Inventor: JODET GERARD
IPC: C21D9/573
Filed: 1998-10-06
Abstract: ESTE HORNO APORTA MEDIOS DE ENFRIAMIENTO RAPIDO POR PROYECCION EN LA BANDA DE UN CHORRO DE GAS DE ATMOSFERA, ESTANDO LA RECIRCULACION DE ESTE GAS GARANTIZADA POR UN CIRCUITO DE CONDUCTOS DE RECIRCULACION QUE COMPRENDEN AL MENOS UN VENTILADOR Y UN INTERCAMBIADOR, Y SE CARACTERIZA PORQUE EL RECINTO (2) EN EL QUE ESTAN ALOJADOS DICHOS INTERCAMBIADORES (28) Y EN EL QUE DESEMBOCAN LOS CONDUCTOS DE RECIRCULACION (18) DEL GAS DE ATMOSFERA COMPRENDE UNA SECCION DE PASO PRINCIPAL (A) POR LA QUE SE EFECTUA LA CIRCULACION DEL GAS DE ENFRIAMIENTO A TRAVES DE DICHOS INTERCAMBIADORES, ESTANDO ESTA SECCION (A) DOTADA DE UN REGISTRO (34) ANTES DE LOS INTERCAMBIADORES DEL O DE DICHOS INTERCAMBIADORES; SECCIONES DE PASO DERIVADO (B), QUE DESVIAN EL FLUJO DEL GAS DE ENFRIAMIENTO EN CASO DE CIERRE DE LA SECCION (A), PARA QUE ESTE FLUJO NO ATRAVIESE DICHOS INTERCAMBIADORES, ESTANDO DICHAS SECCIONES (B) DOTADAS DE REGISTROS (36, 36'') Y ACCIONADORES (38, 38''), CON TIEMPO DE RESPUESTA MUY CORTO, QUE SON ACTIVADOSPOR MEDIOS DE DETECCION DE LA RUPTURA DE LA BANDA O DE UNA ONDA DEL COMPENSADOR Y EN CASO DE CORTE DE LA ALIMENTACION ELECTRICA.
Patent CY-1107096-T1 (CY)
Title: Μεθοδοι και φαρμακοτεχνικες μορφες ελεγχομενης απελευθερωσης παλιπεριδονης
Inventor: YAM NOYMI V
IPC: A61K31/519
Filed: 2007-12-18
Abstract: Προβλέπονται φαρμακοτεχνικές μορφές και μέθοδοι για παροχή ανοδικού κατ’ ουσία ρυθμού αποδέσμευσης παλιπεριδόνης. Οι φαρμακοτεχνικές μορφές παρατεταμένης αποδέσμευσης όταν χορηγούνται εφάπαξ ημερησίως, προσφέρουν θεραπευτικά αποτελεσματικές, μέσης σταθερής κατάστασης συγκεντρώσεις παλιπεριδόνης στοπλάσμα. Το σχήμα των εφάπαξ ημερησίων δόσεων έχει ως αποτέλεσμα να προκύπτει μια μόνο μέγιστη συγκέντρωση παλιπεριδόνης στο πλάσμα κατά την περίοδο του 24ώρου. Επιπλέον, η μέγιστη συγκέντρωση της παλιπεριδόνης στο πλάσμα, επέρχεται σε χρόνο μετά τη χορήγηση της δόσης και εμφανίζεται σε μικρότερο βαθμό σε σχέση με τη μέγιστη συγκέντρωση της παλιπεριδόνης στο πλάσμα που επέρχεται μετά τη χορήγηση παλιπεριδόνης σε φαρμακοτεχνική μορφή άμεσης αποδέσμευσης.
Patent CY-1110350-T1 (CY)
Title: ΣΤΟΧΕΥΜΕΝΗ ΕΝΔΟΚΥΤΤΑΡΙΚΗ ΜΕΤΑΦΟΡΑ ΕΝΩΣΕΩΝ ΜΕ ΠΡΩΤΕΪΝΗ ΘΕΡΜΙΚΟΥ ΣΟΚ 70 kD
Inventor: FUJIHARA SHERI M
IPC: A61K47/48
Filed: 2009-09-21
Abstract: Η παρούσα εφεύρεση παρέχει φορέα για μεταφορά μορίων με βιολογική λειτουργία σε τμήματα κυττάρων και πυρήνα. Ο φορέας που ανακοινώνεται είναι πρωτεΐνη θερμικού σοκ 70 ("Hsp70"), ή θραύσμα της Hsp70 όπως περιγράφεται στο παρόν, ως μέσο για κατευθυνόμενη, μη επεμβατική μεταφορά μορίων, όπως πρωτεΐνες, πεπτίδια ή DNA, που μπορούν να τροποποιήσουν τη γονιδιακή έκφραση. Η παρούσα εφεύρεση περιλαμβάνει επίσης χρήση της Hsp70, ή θραύσματος αυτής, για τροποποίηση κυτταρικής δραστηριότητας, κατά προτίμηση για τροποποίηση δραστηριότητας του πυρήνα σε κύτταρο ή κύτταρα.
Patent CY-1112231-T1 (CY)
Inventor: WALES NICOLAS
IPC: B65B55/02
Filed: 2012-01-11
Abstract: The invention relates to a method of sterilisation and/or pasteurisation of a food product (8) held within a container (12), said container of a type which, in conjunction with the food product, forms a retail pack which can be purchased and the food product removed therefrom for consumption. The containers (12) are moved during the controlled application of heat and pressure during the process to allow a gas space or bubble within the container to move through the food product during the process. This allows the sterilisation and/or pasteurisation to be efficiently achieved. The retail pack and support means (32) for the containers to move the same are also part of the invention.
Patent CY-1114760-T1 (CY)
Title: Θεραπευτικη αγωγη αθηροσκληρωσης
Inventor: BRUNNER SYLVIA
IPC: C07K7/08
Filed: 2014-01-16
Abstract: Η παρούσα εφεύρεση αφορά τη χρήση ενώσεων για την παραγωγή φαρμάκου για την πρόληψη και/ή τη θεραπευτική αγωγή αθηροσκλήρωσης, νόσων κινδύνου αθηροσκλήρωσης και συνεπειών αθηροσκλήρωσης.
Patent CY-1116753-T1 (CY)
Title: Μεθοδοι για την παραγωγη παρασκευασματων υψηλου τιτλου χωρις βοηθους των αποδεσμευμενων ανασυνδυασμενων φορεων aav
Inventor: ATKINSON EDWARD MORROW
IPC: C12N15/86
Filed: 2015-07-08
Abstract: Η εφεύρεση που περιγράφεται στην παρούσα παρέχει μεθόδους παραγωγής των σωματιδίων rAAV μέσω της καλλιέργειας των κυττάρων παραγωγού υπό συνθήκες, όπως είναι η θερμοκρασία και το pΗ, που προωθούν την αποδέσμευση του ιού.
Patent CY-1118819-T1 (CY)
Title: Ετεροκυκλικες ενωσεις αγωνιστες του υποδοχεα ip
Inventor: CHARLTON STEVEN JOHN
IPC: C07D471/04
Filed: 2017-04-11
Abstract: Η παρούσα εφεύρεση παρέχει ετεροκυκλικά παράγωγα τα οποία ενεργοποιούν τον υποδοχέα IP. Η ενεργοποίηση του μονοπατιού σηματοδότησης του υποδοχέα IP είναι χρήσιμη για τη θεραπευτική αντιμετώπιση πολλών μορφών της ΡΑΗ, της πνευμονικής ίνωσης και ασκούν ευεργετικές δράσεις στις ινωτικές παθήσεις ποικίλων οργάνων σε ζωικά μοντέλα και σε ασθενείς. Περιλαμβάνονται επίσης φαρμακευτικές συνθέσεις οι οποίες περιέχουν τα παράγωγα αυτά.
Patent CY-1124630-T1 (CY)
Title: Επιλεκτικη αναγωγη αντισωματων τροποποιημενης κυστεϊνης
Inventor: COUMANS RUDY GERARDUS ELISABETH
IPC: A61K47/68
Filed: 2020-09-02
Abstract: Η παρούσα εφεύρεση σχετίζεται με μία διεργασία για την επιλεκτική αναγωγή αντισωμάτων τροποποιημένης κυστεΐνης η οποία περιέχει την αντίδραση ενός αντισώματος που περιέχει μια ή περισσότερες τροποποιημένες κυστεΐνες σε θέσεις που επιλέγονται από HC40, HC41, HC42, HC89, HC152, HC153, HC155, HC171, LC40, LC41, LC165, και LC168 με μία ένωση σύμφωνα με τον τύπο (Ι), (ΙΙ), (III), (IV), (V), (VI) ή (VII): (Ι) (II) (III) (IV) (V) (VI) (VII) και με μία διεργασία για την παρασκευή συζευγμάτων αντισωμάτων, συμπεριλαμβανομένων συζευγμάτων αντισώματος φαρμάκου (ADCs).
Patent HR-P20110237-T1 (HR)
Inventor: RABOISSON PIERRE JEAN-MARIE BERNARD
IPC: C07D245/04
Filed: 2011-04-01
Abstract: Spoj sa formulomnjegov N-oksid, sol ili stereoizomer, naznačen time, dasvaka isprekidana crta (prikazana sa - - - - -) prikazuje proizvoljnu dvostruku vezu; X je N, CH, a kada X nosi dvostruku vezu, navedeni je C; R1 je -OR7 -NH-SO2R8;R2 je vodik, a kada X je C ili CH, R2 može također biti C1-6alkil; R3 je vodik, C1-6alkil, C1-6alkoksiC1-6alkil, C3-7cikloalkil; R4 je aril ili Het; n je 3, 4, 5 ili 6; R5 predstavlja halo, C1-6alkil, hidroksi, C1-6alkoksi, polihaloC1-6alkil, fenil ili Het; R6 predstavlja C1-6alkoksi ili dimetilamino; R7 je vodik; aril; Het; C3-7cikloalkil koji je proizvoljno supstituiran sa C1-6alkilom; ili C1-6alkil koji je proizvoljno supstituiran sa C3-7cikloalkilom, arilom ili sa Het; R8 je aril; Het; C3-7cikloalkil koji je proizvoljno supstituiran sa C1-6alkilom; ili C1-6alkil koji je proizvoljno supstituiran sa C3-7cikloalkilom, arilom ili sa Het; aril kao skupina ili kao dio skupine je fenil koji je proizvoljno supstituiran sa jednim, dva ili tri supstituenta koji su odabrani iz halo, hidroksi, nitro, cijano, karboksila, C1-6alkila, C1-6alkoksi, C1-6alkoksiC1-6alkila, C1-6alkilkarbonila, amino, mono- ili di-C1-6alkilamino, azido, merkapto, polihaloC1-6alkila, polihaloC1-6alkoksi, C3-7cikloalkila, pirolidinila, piperidinila, piperazinila, 4-C1-6alkilpiperazinila, 4-C1-6alkilkarbonilpiperazinila i morfolinila; pri čemu navedena morfolinilna i piperidinilna skupina može proizvoljno biti supstituirana sa jednim ili sa dva C1-6alkil radikala; Het kao skupina ili kao dio skupine je 5- ili 6-člani zasićeni, djelomično nezasićeni ili u cijelosti nezasićeni heterociklički prsten koji sadrži 1 do 4 heteroatoma od kojih je svaki nezavisno odabran iz dušika, kisika i sumpora, pri čemu je navedeni heterociklički prsten proizvoljno kondenziran sa nekim benzenskim prstenom; i pri čemu navedeni het je u cijelosti proizvoljno supstituiran sa jednim, dva ili tri supstituenta od kojih je svaki nezavisno odabran iz skupine koja se sastoji od halo, hidroksi, nitro, cijano, karboksila, C1-6alkila, C1-6alkoksi, C1-6alkoksiC1-6alkila, C1-6alkilkarbonila, amino, mono- ili di-C1-6alkilamino, azido, merkapto, polihaloC1-6alkila, polihaloC1-6alkoksi, C3-7cikloalkila, pirolidinila, piperidinila, piperazinila, 4-C1-6alkilpiperazinila, 4-C1-6alkilearbonilpiperazinila i morfolinila; a pri čemu morfolinilna i piperidinilna skupina mogu proizvoljno biti supstituirane sa jednim ili dva C1-6alkil radikala. Patent sadrži još 27 patentnih zahtjeva.
Patent SI-1354204-T1 (SI)
Title: Hcv antigen/antibody combination assay
Inventor: CHIEN DAVID Y
IPC: G01N33/577
Filed: 2001-06-14
Abstract: The invention relates to a method of detecting HCV infection in a biological sample, the method comprising providing an immunoassay solid support, comprising an HCV anti-core antibody, an antigen comprising an HCV NS3/4a epitope, and an HCV multiple epitope fusion antigen, that can detect both HCV antigens and antibodies present in a sample. The invention also includes polynucleotides encoding multiple epitope fusion antigens for use in the assay, recombinant vectors and host cells comprising such polynucleotides, and methods of producing the multiple epitope fusion antigens.
Patent SI-1706121-T1 (SI)
Title: Neutral endopeptidase (nep) and human soluble endopeptidase (hsep) inhibitors for prophylaxis and treatment of neurodegenerative disorders
Inventor: WESKE MICHAEL
IPC: A61K31/00
Filed: 2005-01-10
Abstract: The invention relates to a novel use of known benzazepine, benzoxazepine, benzothiazepine-N-acetic acid and phosphono-substituted benzazepinone derivatives having neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity. The compounds of the invention are useful for the preparation of pharmaceutical compositions for prophylaxis and treatment of neurodegenerative disorders. The compounds of the invention are known from the European patents EP 0 733 642 and EP 0 916 679, and can be described by the general formula (1) wherein the symbols have the meanings as given above in the description.
Patent SI-1829262-T1 (SI)
Title: Closed-loop rate control for a mimo communication system
Inventor: WALTON JAY RODNEY
IPC: H04J99/00
Filed: 2005-11-16
Abstract: In a MIMO system, rate control is achieved with an inner loop that selects rates for data streams sent via a MIMO channel and an outer loop that regulates the operation of the inner loop. For the inner loop, SNR estimates are obtained for each data stream based on received pilot symbols and/or received data symbols. An effective SNR is derived for each data stream based on the SNR estimates, a diversity order, a MIMO backoff factor, and an outer loop backoff factor for the data stream. The rates are then selected for the data streams based on the effective SNRs for the data streams. The outer loop adjusts the outer loop backoff factor for each data stream based on the performance (e.g., packet errors and/or decoder metrics) for the data stream.
Patent SI-2073008-T1 (SI)
Title: Improved immunoassay methods
Inventor: ROBERTSON JOHN FORSYTH RUSSELL
IPC: G01N33/574
Filed: 2006-05-26
Abstract: The invention generally relats to the field of diagnostic or prognostic assays. In particular, the invention provides a method of determining an antibody profile in a test sample comprising a bodily fluid from a mammalian subject, wherein the antibody is a biological marker of a disease state or disease susceptibility.
Patent SI-2084529-T1 (SI)
Title: Stable cell lines and methods for evaluating gastrointestinal absorption of chemicals
Inventor: OWEN ALBERT J III
IPC: C12N15/113
Filed: 2007-11-09
Abstract: Nucleic acids and vectors for interfering with the expression of membrane efflux transport proteins in cells that express such proteins are provided. Also provided are cells and cell lines comprising such nucleic acids and vectors. Methods for screening chemicals and biomolecules for gastrointestinal absorption in animals, and kits for practicing such methods are also provided.
Patent SI-2188302-T1 (SI)
Title: Prevention of disulfide bond reduction during recombinant production of polypeptides
Inventor: KAO YUNG-HSIANG
IPC: C07K14/00
Filed: 2008-07-08
Abstract: The invention concerns methods and means for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide-containing polypeptides, including antibodies, from recombinant host cell cultures.
Patent SI-2800743-T1 (SI)
Title: Therapeutically active compounds and their methods of use
Inventor: CIANCHETTA GIOVANNI
IPC: C07D493/00
Filed: 2013-01-05
Abstract: Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein.
Patent SI-3036040-T1 (SI)
Title: Process for the conversion of sugars to lactic acid and 2-hydroxy-3-butenoic acid or esters thereof comprising a metallo-silicate material and a metal ion
Inventor: HOLM MARTIN SPANGSBERG
IPC: C07C69/00
Filed: 2014-08-15
Abstract: A process for the preparation of lactic acid and 2-hydroxy-3-butenoic acid or esters thereof from a sugar in the presence of a metallo-silicate material, a metal ion and a solvent, wherein the metal ion is selected from one or more of the group consisting of potassium ions, sodium ions, lithium ions, rubidium ions and caesium ions.
Patent SI-3021696-T1 (SI)
Title: Smoking article having a particle containing wrapper
Inventor: GUYARD AURELIEN
IPC: A24D1/00
Filed: 2014-07-15
Abstract: A smoking article includes a tobacco rod and a wrapper disposed about the tobacco rod. The wrapper includes a plurality of aggregated particles. The aggregated particles include particles of functional material and a whitener bound in a polymeric binder. The particles of functional material may be a catalyst or an oxidant, such as an iron oxide-containing particle. The whitener may be calcium carbonate.