baber/WOPTO huggingface dataset:
Patent DE-69737323-T2 (DE)
Inventor: BOREN THOMAS
IPC: C12P21/08
Filed: 1997-06-10
Granted: 2007-11-08
Abstract: A novel Helicobacter pylori blood group antigen binding (BAB) adhesin protein was isolated and purified, whereby said protein or fractions thereof bind specifically to fucosylated blood group antigens. The protein sequence of said adhesin is disclosed in this application. Simultaneously the DNA sequences for two genes, babA and babB, producing highly similar proteins, are disclosed. Said adhesin and/or DNA is useful for diagnose and therapy and/or prophylaxis directed against H. pylori induced infections, e.g. gastritis and acid peptic disease, i.e. active vaccination. A new immunoglobulin composition, which exhibits specific activity to a Lewis<SUP>b </SUP>antigen binding Helicobacter pylori adhesin, or preferably, monoclonal and/or polyclonal antibodies to said adhesin offer a new and more efficient method of treatment and/or prevention of gastrointestinal diseases, caused by Helicobacter pylori or other Helicobacter species, i.e. passive vaccination.
Patent DE-69812459-T2 (DE)
Inventor: ANATRINI DARIO
IPC: B65B3/00
Filed: 1998-04-30
Granted: 2004-02-26
Abstract: A device for centring a plurality of cylinders (6) of single-use syringes in automatic filling and packaging machines, which cylinders are seated in through holes (70) provided in a support (7), comprises: a plurality of foils (1) having their edges provided with recesses (16) and positioned with the longitudinal axes parallel and lying on at least one plane, which foils are hinged at one end in such a way as to be able to effect rotations around their own longitudinal axes, a plurality of non shaped rods (2), positioned parallel and alternated to the foils (1) on the same plane or on the same planes, which rods co-operate with the recesses provided in the edges of the foils to form seats for locking the cylinders in place; a mechanical actuator (3), acting on the ends of the foils with a system of levers and/or gears, which actuator can assume two positions, in correspondence with which the foils are oriented with the surfaces lying in the plane or in the planes containing the longitudinal axes and respectively with the surfaces orthogonal to said plane(s). <IMAGE>
Patent DE-69825597-T2 (DE)
Inventor: MARTI ERWIN
IPC: A61K31/505
Filed: 1998-08-25
Granted: 2005-09-15
Abstract: The present invention relates to several new, polymorphous crystal forms of Dicyclanil, and hydrates and solvates thereof, as well as the preparation thereof. In particular, the invention relates to substantially pure crystal forms of Dicyclanil, having characteristic lattice structures, which are effective for the control of insects and ectoparasites.
Patent DE-69828802-T2 (DE)
Inventor: KATO JINICHIRO
IPC: C08G63/183
Filed: 1998-09-03
Granted: 2005-12-22
Abstract: A polyester resin composition is disclosed, comprising poly(trimethylene terephthalate) in a proportion of 90 wt% or more, wherein the resin composition has an intrinsic viscosity of from 0.4 to 2 and contains a phosphorus compound corresponding to from 10 to 250 ppm in terms of the amount of phosphorus element, a cyclic dimer in an amount of not exceeding 3 wt% and a bis(3-hydroxypropyl)ether in an amount of 2 wt% or less. This polyester resin composition has excellent spinning stability and high melt stability and is used for the production of a poly(trimethylene terephthalate)-based fiber having excellent whiteness and high tenacity.
Patent DE-69829782-T2 (DE)
Inventor: LU DAOPEI
IPC: A61K9/48
Filed: 1998-07-06
Granted: 2006-03-09
Abstract: The present invention relates to arsenic sulphide compounds. The present invention also relates to pharmaceutical compositions useful treating cancer, such as leukaemia or lymphoma, which comprises an arsenic sulfide compound. The present invention further relates to methods for treating cancer, such as leukaemia or lymphoma, using an arsenic sulphide compound. Finally, the present invention relates to processes for producing arsenic disulfide (As4S4).
Patent DE-69836961-T2 (DE)
Inventor: CHURCH C
IPC: A61K49/00
Filed: 1998-06-30
Granted: 2007-10-18
Abstract: It has been discovered microparticles formed from natural or synthetic polymer with thicker walls have significantly enhanced echogenicity as compared with microparticles having thinner walls. The effect of wall thickness has been determined experimentally as well as inserted into a formula for use in predicting the optimum conditions. In the preferred embodiment, the polymers are synthetic biodegradable polymers and the wall thickness is between about 100 and 660 nm, although wall thicknesses from about 20 nm to in excess of 500 nm can be used. The microparticles are manufactured with a diameter suitable for the targeted tissue to be imaged, for example, with a diameter of between 0.5 and 8 microns for intravascular administration, and a diameter of between 0.5 and 5 mm for oral administration for imaging of the gastrointestinal tract or other lumens. Preferred polymers are polyhydroxy acids such as polylactic acid-co-glycolic acid, polylactide or polyglycolide, most preferably conjugated to polyethylene glycol or other materials inhibiting uptake by the reticuloendothelial system (RES). The microspheres may be used in a variety of ultrasound imaging applications including cardiology applications, blood perfusion applications as well as for organ and peripheral vein imaging.
Patent DE-69901684-T2 (DE)
Inventor: DIVOUX JEAN-NOEL
IPC: H01L27/08
Filed: 1999-01-21
Granted: 2003-01-09
Abstract: The present invention concerns an oscillator (20) intended to supply a periodic electric voltage (Vo) at a predetermined frequency (f). This oscillator includes: a reference source (23) able to provide a reference voltage (Vref), this reference source including a resistor (R) linked to said voltage; and supply means (24) able to receive the reference voltage and to supply said periodic voltage at said predetermined frequency, the supply means having a first temperature coefficient (alpha24) so this frequency can vary under the influence of the temperature. This oscillator is characterised in that the resistor is formed to give the reference source a second temperature coefficient (alpha23) equal to the first temperature coefficient, so that the temperature has the same influence on the reference voltage and on the supply means, which allows the periodic voltage to be supplied independently of the temperature.
Patent DE-69903858-T2 (DE)
Inventor: KATZ SAMUEL
IPC: B22F3/00
Filed: 1999-01-06
Granted: 2003-07-17
Abstract: A metal-ceramic laminar-band multi matrix composite, intended for use in oxidizing, reductive or inert media at temperatures up to 1500  DIVIDED  2800  DEG C and a method of the manufacture is provided. The composite material contains up to 85 vol. % of an oxide component, for example, yttria, zirconia, hafnia, up to 85 vol. % of a compound devoid of oxygen, such as zirconium carbide, and 15  DIVIDED  75 vol. % of a refractor metal, such as tungsten, molybdenum or chromium. Each of the above mentioned components of the composite exists in the form of a plurality of curved tapes. The tapes of every component are joined with the tapes of other components forming multilayer curved band-like chips, which are randomly interlaced in a compact 3-dimensional pattern of the chips. The novel composites have high mechanical properties, are thermal- and crack resistant, and have a good thermal-shock and oxidation-erosion resistance at temperatures of 1200  DEG C to 2800  DEG C.
Patent DE-69908397-T2 (DE)
Inventor: DEBATIN MICHAEL
IPC: C07J63/00
Filed: 1999-10-28
Granted: 2004-04-01
Abstract: The present invention is, generally, directed to the use of betulinic acid and derivatives thereof for the treatment of neuroectodermal tumors. The present invention is based on the discovery that betulinic acid and its derivatives are potent anti-neuroectodermal agents. As disclosed herein, betulinic acid and its derivatives are useful for the treatment of neuroectodermal tumors, including, due to its distinct mechanism of action, neuroectodermal tumors that are resistant to conventional chemotherapeutical agents. In addition to the new use of known compounds, the invention discloses novel compounds and pharmaceutical compositions for the treatment of neuroectodermal tumors.
Patent DE-69908819-T2 (DE)
Inventor: JUDICE KEVIN
IPC: A61K38/14
Filed: 1999-12-22
Granted: 2004-05-06
Abstract: Disclosed are derivatives of glycopeptide compounds having at least one substituent of the formula: —Ra—Y—Rb—(Z)x where Ra, Rb, Y, Z and x are as defined, and pharmaceutical compositions containing such glycopeptide derivatives. The disclosed glycopeptide derivatives are useful as antibacterial agents.
Patent DE-69910317-T2 (DE)
Inventor: ROSSEEL ALEXIS
IPC: B60K15/035
Filed: 1999-07-28
Granted: 2004-06-24
Abstract: The valve (1) comprises an obturator (14) which moves in the valve housing (13) to open and close an orifice (12). This orifice allows a gaseous flow to leave the tank via a charcoal filter to a free atmosphere. The housing communicates with the gaseous environment of the valve inside the tank by means of a passage, constituting the top of a chicane formed by two communicating annular grooves (25,26).
Patent DE-69921115-T2 (DE)
Inventor: ELMS RICHARD
IPC: B63B1/24
Filed: 1999-05-06
Granted: 2005-11-17
Abstract: A hydrofoil device is useable as a hydrofoil wing, propeller blade, etc. In a water flow, a relatively lower pressure is generated on a second surface (94) of the device compared with a first surface (96). Near the trailing end of the first surface a protrusion in the form of an adjustable interceptor (98) is provided. The face of this protrusion defines an included angle to the upstream direction of less than or equal to 90° so that water flow thereat is deflected back on itself thereby increasing the local pressure on the first surface. A second protrusion may be provided near the leading edge of the second surface (94) to encourage flow separation thereat. Air may be provided adjacent each protrusion to provide natural ventilation if the pressure of the water flow drops below atmospheric pressure.
Patent DE-69921435-T2 (DE)
Inventor: GAILLAC DAVID
IPC: C12N7/00
Filed: 1999-12-17
Granted: 2006-03-02
Abstract: Inactivation of a virus coated in a viral preparation containing principally non coated virus is new and comprises introducing into the viral preparation an sufficient quantity of a solvent and leave to adjust to a temperature of -5 - 50 degrees C, at a pH of 5-9 for a sufficient amount of time to significantly reduce the amount of viral preparation coated virus.  Independent claims are also included for the following:  (1) a process for the preparation of the viral preparation; and  (2) the viral preparation.
Patent DE-69928284-T2 (DE)
Inventor: PRUNISER B
IPC: A61K35/76
Filed: 1999-12-13
Granted: 2006-08-10
Abstract: The present invention comprises a method for producing mammalian therapeutics free from prion contamination and cells for use in such methods. Such therapeutics are produced in somatic cells having a genome with an artificially altered PrP gene. The PrP gene in these cells may be ablated, or replaced by an exogenous inducible form of the PrP gene. The endogenous gene in the host cells may be disrupted, or disrupted and replaced by an exogenous PrP gene.
Patent DE-69931475-T2 (DE)
Inventor: ROCK KELLY
IPC: B01F23/30
Filed: 1999-03-11
Granted: 2006-10-19
Abstract: This disclosure relates to a centrifugal vortex system for preparing a liquid, such as fuel and includes a chamber housing defining a vortex chamber. An array of tangential apertures are formed in the chamber housing to permit fluid to be turbulently introduced into the vortex chamber to create a vortical flow of fluid through the vortex chamber. In one embodiment, a plurality of vortex chambers are arranged in series to allow the fluid to pass through several vortex chambers. In other embodiments, the chamber housing may be stepped, textured, or both to increase the turbulence of the flow through the chamber. In yet another embodiment, a pressure differential supply jacket is provided to normalize the amount of flow through the tangential apertures according to the location of the apertures. A centrifuge chamber is also disclosed which has a plurality of output conduits on a bottom surface and a tapered extension member downwardly extending from a top surface to enhance the centrifugal flow of the fluid. Additionally, a bypass conduit is provided to selectively permit the flow to bypass one or more chambers.
Patent DE-69938622-T2 (DE)
Inventor: COIA GREGORY
IPC: C07K16/00
Filed: 1999-03-05
Granted: 2009-06-10
Abstract: The present invention relates to binding moieties comprising at least one monomeric V-like domain (VLD) derived from a non-antibody ligand, the at least one monomeric V-like domain being characterised in that at least one CDR loop structure or part thereof is modified or replaced such that the solubility of the modified VLD is improved when compared with the unmodified VLD.
Patent HU-E026740-T2 (HU)
Title: Treatment of multiple sclerosis (ms) with campath-1h
Inventor: SACHSE ANDREAS
IPC: C07K16/28
Filed: 2007-09-11
Abstract: A method for treatment of multiple sclerosis (MS) with Campath-1H with significant efficacy and a favourable safety profile is described, which offers an acceptable benefit/risk ratio. Especially described is the use of Campath-1H (alemtuzumab) for the production of a medicament for the treatment of multiple sclerosis (MS), comprising a first treatment cycle followed by at least one further treatment cycle of Campath-1H (alemtuzumab), in which each treatment cycle comprises 1-5 daily doses which are applied on consecutive days, wherein the daily dose is >0 and ≤ 12 mg, and wherein each treatment cycle is separated from the next cycle by at least 1 - 24 months. Also described are treatment regimens comprising the administration of less than 12 mg/day of Campath-1H for a period of 1-5 consecutive days.
Patent HU-E029225-T2 (HU)
Title: Rsv-specific binding molecules and means for producing them
Inventor: SPITS HERGEN
IPC: A61K39/00
Filed: 2008-05-30
Abstract: The invention provides antibodies and functional equivalents thereof which are capable of specifically binding RSV, and means and methods for producing them.
Patent MD-3638698-T2 (MD)
Inventor: PURCELL LISA
IPC: C07K16/40
Filed: 2019-01-24
Abstract: Prezenta invenţie include un anticorp sau un fragment de legare a antigenului acestuia care se leagă în mod specific de TMPRSS2 şi metode de utilizare a acestor anticorpi şi fragmente pentru tratarea sau prevenirea infecţiilor virale (de exemplu, infecţii cu virus gripal).
Patent TR-200000108-T2 (TR)
Title: Deterjan terkipleri.
Inventor: EMERY WILLIAM DEREK
IPC: C11D17/06
Filed: 1998-05-11
Abstract: Yüksek hacimli yogunluguna (en az 600gr/lt) sahip en az % 10 kadar deterjan yüzey aktif maddesi ve agirlikça % 10 dan % 70 e kadar kuvvetlendirici içeren tanecikli bir deterjan terkibi veya bileseni olup, bu terkip, en az iki ve tercihan en az üç farkli granül yapida bilesenden meydana gelir: (i) agirlikça en az % 60 anyonik yüzey aktif madde ihtiva eden granüller, (ii) agirlikça en az % 20 noniyonik yüzey aktif madde, ve agirlikça % 10 dan az alüminosilikat ihtiva eden granüller, (iii) istege bagli olarak, deterjan kuvvetlendirici ihtiva eden granüller.
Patent TR-200000803-T2 (TR)
Inventor: BARTELINK CAMIEL F
IPC: D06M15/643
Filed: 1998-09-28
Abstract: Disclosed is a polyurethane based composition for treating textiles to provide such treated textile with oil, water or oil and water repellency. The composition comprises a polyfunctional liquid polyurethane-containing adduct wherein the adduct contains as a first functional group at least one structo-terminal blocked isocyanate moiety per molecule, and at least one second structo-terminal functional group per molecule which is a perfluoro or siloxane moiety.
Patent TR-200001089-T2 (TR)
Inventor: LOTH HELMUT
IPC: C08K5/09
Filed: 1998-10-31
Abstract: This invention relates to a jointing compound of an acrylate/acrylonitrile copolymer containing 2 to 8 carbon atoms in the alcohol component as binder and fatty compounds as plasticizer and also fillers and auxiliaries. Epoxystearic acid methyl ester in particular may be used as the fatty compound while a butyl acrylate/acrylonitrile copolymer in particular may be used as the acrylate/acrylonitrile copolymer. The combination of the two substances results in jointing compounds characterized by a dramatic improvement in elasticity (resilience). Accordingly, they are particularly suitable for substrates with different coefficients of thermal expansion.
Patent TR-200001173-T2 (TR)
Inventor: CLASSON BJOERN
IPC: C07D407/12
Filed: 1998-04-03
Abstract: Compounds of the formula  I :   
wherein: 
A' and A" are independently the same or different group of the formula  II :   
wherein:  R' is H, CH 3 , C(CH 3 ) 2 , -OR a , -N(R a ) 2 , -N(R a )OR a  or -DP  R''' is H or CH 3 ; R a  is H, C 1 -C 3  alkyl;  D is a bond, alkylene, -C(=O)-, -S(O)- or -S(O) 2 - ;  P is an optionally substituted, mono or bicyclic carbo- or heterocycle;  R" is H, any of the sidechains found in the natural amino acids, carboxacetamide, or a group (CH 2 ) n DP;  M is a bond or -C(=O)N(R''')-;  Q is absent, a bond, -CH(OH)- or -CH 2 -;  or R" together with Q , M and R' define an optionally substituted 5 or 6 membered carbo- or heterocyclic ring which is optionally fused with a further 5 or 6 membered carbo- or heterocyclic ring;  with the proviso that R' is -OR a , -N(R a ) 2 , -N(R a )OR a  or -DP, if M is a bond and Q is absent; X is H, OH, OCH 3 ;  Y is H, OH, OCH 3 , but X and Y are not both H;  Z' and Z" are independently -(CH 2 ) m P where P is as defined above;  n and m are independently 0,1 or 2;  and pharmaceutically acceptable salts and prodrugs thereof have utility as aspartyl protease inhibitors of HIV. They can be prepared in a facile two step synthesis from novel 2,5-di-O-benzyl-L-mannaro-1,4:6,3-dilactone intermediates.
Patent TR-200100446-T2 (TR)
Title: Mikro dalga fırın.
Inventor: KURAL CEM
IPC: H05B6/64
Filed: 1998-08-10
Abstract: Bir mahfaza (4), mahfaza (4) içinde pisirme isleminin gerçeklestirildigi bir pisirme alani (6), pisirme alani (6) içinde bir kizil ötesi izgarasi (8), kizil ötesi izgarasi (8) ile mahfaza (4) arasinda yer alan ve kizil ötesi izgarasindan (8) isiyi pisirme alanina (6) geri yansitan bir reflektör (10), reflektörle (10) mahfaza (4) arasinda bir bosluk (12), mikro dalga üreten bir cihaz (14) ve mikro dalgalarin, reflektörle (10) mahfaza (4) arasindaki bosluk vasitasiyla kontrollü olarak pisirme alanina (6) verilmesi için mahfaza (4) disinda konumlanmis olup söz konusu bosluk (12) ve mahfazadaki (4) bir açiklik (18) vasitasiyla iletisim kuran bir temin düzenegi (16) içeren bir mikro dalga firini.
Patent TR-200101277-T2 (TR)
Title: Pest kontrolünde makrolidlerin kullanımı.
Inventor: HOFER DIETER
IPC: A01N43/00
Filed: 1998-12-21
Abstract: Tahta pestlerini ve mollusklari (yumusakçalar sinifindan bir hayvani) kontrol etmenin metodu olup, pestisidal olarak aktif bilesik olarak, serbest formdaki veya agrokimyasal olarak faydalanilabilen tuz formundaki aktif muhteviyat olarak en az bir makrolid bilesikten ve en az bir yardimci maddeden olusan bir pestisidin, pestisidal olarak aktif miktarinin; pestlere ve söz konusu pestlerin ortamlarina uygulanmasiyla karakterize edilmektedir.
Patent TR-200102025-T2 (TR)
Title: Dopamin-D3-Reseptör afinitesine sahip triazol bileşikleri
Inventor: STARCK DOROTHEA
IPC: C07D413/14
Filed: 2000-01-12
Abstract: Isbu bulus, formül (1)'in, içinde R1, R2, A ve B'nin tanimlamada belirtilmis olan anlamlara sahip oldugu triazol bilesimleri ile ilgilidir.Bulusa uygun bilesimler Dopamin-D3-Reseptörüne yönelik kuvvetli bir çekime sahiptirler ve bu nedenle Dopamin-D3-Baglari araciligi ile tepki veren hastaliklarin tedavisinde kullanislidirlar.
Patent TR-200201205-T2 (TR)
Title: N-ikame edilmiş karbamoiloksialkil-azolyum türevleri.
Inventor: FUKUDA HIROSHI
IPC: C07D417/06
Filed: 2000-10-25
Abstract: Q, Y, R1, R2, R3, Y ve X' in istemlerde ve tarifte tanimlandigi gibi oldugu genel formül (I)'e ait N-ikame edilmis karbamoiloksialkil-azolyum türevleri ve ayni zamanda bunlarin tuzlari, hidratlari veya solvatlari. Mevcut bulusa ait bilesikler, anti-mantar aktivitesine sahiptir ve bunlar, mantar hastaliklarinin tedavisinde faydalidir.
Patent TR-200202737-T2 (TR)
Title: Aktif katkı maddeleri ihtiva eden şekerleme ürünleri.
Inventor: BELL DAVID ALAN
IPC: A23G4/00
Filed: 2001-06-06
Abstract: Bir sekerleme ürünü, örnegin, bir ya da daha çok aktif katki maddesini ihtiva eden çikolata olup, bu ürünün özelligi, aktif katki maddelerinin, sekerleme ürününün gövdesi içinde dagitilmis bir çok tasiyici gövdeye katilmis olusudur.
Patent DE-602004001511-T2 (DE)
Inventor: BEAUDOIN MICHEL
IPC: E05D13/00
Filed: 2004-01-27
Granted: 2007-01-18
Abstract: A cable failure device for a cable-operated door operated by a tensioned cable, the cable-operated door having a movement guided along a fixed structure, such as a guide rail. The cable failure device is configured for cooperating with the tensioned cable so as to immobilize the cable-operated door with respect to the fixed structure in the event of a loss of tension in the cable. The cable failure device included a support bracket for mounting the cable failure device onto the door, a guiding assembly operatively mounted for guiding the movement of the door along the fixed structure, and a braking assembly operatively mounted onto the support bracket, and operable between a rest position where the guiding assembly is allowed to guide the door along the fixed structure, and an operable position triggered by a given loss of tension detected in the tension cable where the braking assembly engages a portion of the fixed structure for braking movement of the cable-operated door with respect to the fixed structure. The cable failure device also includes a safety arm operatively connected to the braking assembly and cooperating with the tensioned cable so as to detect the given loss of tension. The safety arm is operable between a safety configuration where it is positioned over at least one fastener of a corresponding hole of the support bracket when there is still a given tension in the tensioned cable, for preventing a user from removing the support bracket from the door, and a retracted configuration where the safety arm is positioned away from the fastener when the given tension is no longer present in the cable, thereby enabling the user access to the fastener. Thus, the cable failure device is configured for immobilizing the door in the event of a loss of tension and for preventing a user from removing the device from the door when there is still tension in the cable.