baber/WOPTO huggingface dataset:
Patent RU-2715388-C1 (RU)
Title: Method of preparation and cytomic analysis of hepatocytes of laboratory animals and humans for assessing cytogenetic and cytotoxic action of factors of different nature
Inventor: Sycheva Lyudmila Petrovna
IPC: G01N33/483
Filed: 2018-09-17
Granted: 2020-02-27
Abstract: FIELD: medicine. 
     SUBSTANCE: group of inventions refers to medicine, namely cytology, and can be used for assessing cytogenetic and cytotoxic action of various factors on hepatocytes of experimental animals and humans. That is ensured by producing liver hepatocytes after animal euthanasia or human biopsy. Preparation is then fixed in 10 % formalin and alkaline dissociation of 50 % KOH is carried out at 25–37 °C for three hours. Thereafter, cell suspension is applied by smear method on dry slide glass, staining with aceto-orsine with green-green docking of cytoplasm and analyzed by 1000 hepatocytes light microscope. Hepatocyte cytomic analysis involves determining the following cytological parameters: determining cells with microcapsules, cells with nuclear protrusions, cells with internuclear bridges and the sum of cells with these parameters. Additionally quantitative change of single-core diploid (2n), tetraploid (4n), polyploid (≥8n), binuclear diploid (2n + 2n), tetraploid (4n + 4n) and polyploid (≥8n + 8n) hepatocytes. Ploidy index is then calculated as the ratio of the sum of polyploid hepatocytes to the sum of diploid hepatocytes and the nuclear index as the ratio of the sum of binuclear hepatocytes to the sum of mononuclear hepatocytes. 
     EFFECT: group of inventions provides simplifying the method of preparing hepatocytes for analysis, as well as high information value of assessing cytogenetic and cytotoxic action of various factors on the body. 
     2 cl, 1 dwg, 4 tbl, 6 ex
Patent RU-2685120-C1 (RU)
Title: Method of making articles with antistatic properties
Inventor: IVANOV EVGENIJ VLADIMIROVICH
IPC: B29C70/18
Filed: 2018-12-04
Granted: 2019-04-16
Abstract: FIELD: technological processes.SUBSTANCE: invention relates to composite materials and relates to a method of producing a composite fiberglass sheet with antistatic properties and an article made therefrom. Method for production of composite fiberglass antistatic sheet with thickness of 0.5 to 10.0 mm for production of pressed articles consists in the fact that at the first stage polyester resin and powder additives with nanocomponent, which imparts antistatic properties to the sheet, is mixed in a dissolver to form a paste which is fed into containers, wherefrom it is applied on the films moving under them at the second step, and at that, at the second stage chemical thickening of polyester resin is applied by adding into the paste composition a thickener which increases viscosity for possibility of subsequent pressing in 3–5 days, and simultaneously reinforcing glass fiber is fed into a ruby machine located above the surface of the paste applied on one of the films, is cut into pieces of a given length and randomly supplied to the surface of the paste layer, from the second layer from the film with paste is rolled on and fed into the sealing system of rollers, where glass fiber impregnation and removal of air bubbles occur, resulting in a sheet which is wound on steel rollers arranged on the rack. Obtained sheet is cut on a table, removing edges depleted of glass fiber, at that, the cuttings are placed in the centre of the suspension in a pile which is placed in a mold, and an article is formed.EFFECT: invention provides antistatic properties throughout the volume of the sheet and the finished product.2 cl, 2 dwg
Patent RU-2716025-C1 (RU)
Title: DOSAGE FORM WITH IMPROVED CHARACTERISTICS OF pH-DEPENDENT RELEASE OF PREPARATION CONTAINING ESOMEPRAZOLE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
Inventor: KWON TAEK KWAN
IPC: A61P1/04
Filed: 2017-07-24
Granted: 2020-03-05
Abstract: FIELD: medicine; pharmaceuticals. 
     SUBSTANCE: presented is a dosage form containing esomeprazole or its pharmaceutically acceptable salt for treating gastric and reflux oesophageal diseases. Dosage form comprises a nucleus containing esomeprazole, a layer of endothelial coating formed on the nucleus, and a coating release coating layer formed on the endothelial coating layer. Layer of endothelial coating contains at least one substance selected from hydroxypropyl methyl cellulose, polyvinylpyrrolidone, low-substituted hydroxypropyl cellulose, starch and gelatin. Layer of release-controlling coating contains a polymer in which copolymer S of methacrylic acid and copolymer L of methacrylic acid are mixed in weight ratio of 1.5:1 to 3.5:1 as base material of release-controlling coating, where methacrylic acid copolymer S is an anionic copolymer containing methacrylic acid and methyl methacrylate in ratio of 1:2, and methacrylic acid copolymer L is an anionic copolymer containing methacrylic acid and methyl methacrylate in ratio of 1:1. Weight of copolymer S of methacrylic acid and copolymer L of methacrylic acid as base materials of release-controlling coating ranges from 15 to 40 % relative to weight of the tablet with endothelial coating. Dosage form when eliciting release after 2 hours elutes 5 % or less of esomeprazole or its pharmaceutically acceptable salt, and after 6 hours eluates at least 90 % of esomeprazole or its pharmaceutically acceptable salt. Described also is a method for preparing a dosage form of esomeprazole. 
     EFFECT: dosage form according to the invention is characterized by improved characteristics of pH-dependent release of the preparation, starts releasing esomeprazole or its pharmaceutically acceptable salt after a given delay time for oral administration, continues release for a given time and ends the release through a predetermined time, thereby providing excellent patient comfort and excellent therapeutic effects compared to other standard forms. 
     8 cl, 2 dwg, 10 tbl, 4 ex
Patent RU-2699137-C1 (RU)
Title: Method for treatment of inner and outer surfaces of articles made by an additive method, and a device for its implementation
Inventor: GILMUTDINOV ALBERT KHARISOVICH
IPC: C25F3/16
Filed: 2019-02-25
Granted: 2019-09-03
Abstract: FIELD: technological processes. 
     SUBSTANCE: invention relates to plasma engineering for electrolytic-plasma treatment of articles of complex shape made using additive technologies. Electrolytic-plasma treatment of internal surfaces of articles of complex shape is carried out using an additional switchable flexible cathode, which is introduced into inner cavities of part or is supplied to outer surface of article by a given distance. Device for local treatment of inner and outer surfaces of articles made by an additive method is characterized by using a flexible movable cathode enclosed in a flexible dielectric hollow shell in the inner space of which an electrolyte is pumped. Cathode is introduced into the inner cavities of the processed article being an anode. 
     EFFECT: reduced degree of roughness of external and internal surfaces of parts made using additive technologies. 
     2 cl, 2 dwg
Patent RU-2727903-C1 (RU)
Title: Novel d-psicose-3-epimerase and method of producing d-psicose using thereof
Inventor: KIM SU JIN
IPC: C12N15/61
Filed: 2017-11-15
Granted: 2020-07-24
Abstract: FIELD: biotechnology.SUBSTANCE: invention relates to the biotechnology. Described is the use of the D-psicose-3-epimerase enzyme to obtain D-psicose from D-fructose, as well as a method for preparing the latter using said enzyme or microorganism producing it.EFFECT: invention enables to obtain D-psicose monosaccharide from D-fructose using said enzyme.9 cl, 5 dwg, 4 tbl, 4 ex
Patent RU-2723342-C1 (RU)
Inventor: Rubtsov Vitalii Iurevich
IPC: B21H1/14
Filed: 2019-06-06
Granted: 2020-06-09
Abstract: FIELD: rolling production.SUBSTANCE: invention relates to rolling, particularly, to methods for controlling the speed of rolls of a ball rolling mill. Method includes control of rolls rotation frequency in process of billet feeding into rolls, billet rolling and billet gripping. Increase in resistance of flanges of ball rolling rolls is provided due to the fact that in period between rolling of billet and grip of subsequent billet at load drop, roll speed is reduced to 20–50 % of operating frequency depending on diameter of rolled billet and mill characteristics, and after gripping subsequent billet and appearance of roll moment, rotational speed of rollers is increased to operating frequency, at that control of rolls rotation frequency is performed automatically depending on fixed load by logic code.EFFECT: technical result consists in a specific contact pressure is lowered to the most wear of the rim at the capture location.1 cl, 2 dwg
Patent RU-2702608-C1 (RU)
Title: Method of reinnervation of facial muscles
Inventor: NEROBEEV ALEKSANDR IVANOVICH
IPC: A61B17/00
Filed: 2019-06-17
Granted: 2019-10-08
Abstract: FIELD: medicine. 
     SUBSTANCE: invention refers to medicine, namely to maxillofacial, reconstructive, plastic surgery. Skin and subcutaneous fat are dissected on an affected and healthy sides with preauricular-postaural approach. Further, along the hair growth line, delamination of the skin-fat flap to the front edge of the parotid gland with subsequent release of the muscular-aponeurotic layer, separation and mobilization of the posterior edge of the parotid gland from the cartilaginous part of the external ear – antilobium, antitragus and intertragic notch. On the involved side, the facial nerve is isolated and cut off within the exit of the thymus-like opening and the parenchyma of the parotid glands is excised. Further, the trunk and branches of the facial nerve are separated in the parotid gland and the facial nerve is divided into an upper part with temporal, bilge and cheek branches and a lower portion with marginal and cervical branches. Sublingual nerve is extracted in the area of an apex of the digastric muscle to dissect 30–40 % of its fascicles. Then the fascia-shaped case of chewing muscle is dissected, its fibers are expanded to reach a half-moon incision, the chewing branch of the trigeminal nerve in it is cut off as much as possible to a arcus zygomaticus. On a healthy side, an anterior edge of the parotid gland is separated by a buccal branch of the facial nerve with subsequent dissection of 0.5–0.75 of its diameter. That is followed by sampling of an autograft nerve that is delivered from an affected side to a healthy one under a previously isolated skin-fat flap through an oral cavity under the mucous membrane and sutured together with a buccal branch of the facial nerve, followed by layer-by-layer soft tissue suturing. Recovered autograft of nervus suralis 30–36 cm long is divided into three lengths 20–25 cm, 6.0–6.5 cm and 4.0–4.5 cm. On the healthy side, the cheek branch of the facial nerve is sutured together with the end of segment 20–25 cm long autograft from an affected side to a healthy one under a previously isolated skin-fat flap through an oral cavity under the mucous membrane. On the involved side, the other end of the segment is sutured together with an upper portion of the facial nerve and the end of a segment of the autograft nerve length of 6.0–6.5 cm, other end of a segment of an autograft nerve in length 6.0–6.5 cm is stitched with a sublingual nerve, the end of a segment of an autograft nerve end of length 4.0–4.5 cm is stitched together with a chewing branch of a trigeminal nerve, other end of the given segment is stitched with the lower part of a trunk of facial nerve. 
     EFFECT: method allows increasing functional and aesthetic results of treatment, as a result, patients have a high degree of facial muscle excursion. 
     1 cl, 1 dwg, 2 ex
Patent RU-2719882-C1 (RU)
Title: Development method of super-viscous oil deposit at late stage
Inventor: AMERKHANOV MARAT INKILAPOVICH
IPC: E21B7/04
Filed: 2019-09-30
Granted: 2020-04-23
Abstract: FIELD: oil and gas industry. 
     SUBSTANCE: invention relates to oil industry, in particular, to methods for increasing production of super-viscous oil at deposit. Method involves construction of pairs of horizontal production and injection wells placed one above the other, equipped in the horizontal part with corresponding tail filters, heating the deposit by pumping of heat carrier – steam into both wells with heating of productive formation and creation of steam chamber, steam injection through injection wells, product selection due to steam and gravity drainage through production wells and monitoring of the state of the steam chamber. After development of the deposit site, the injection of steam and the selection of fluid in one of the pairs of wells are stopped. After lowering temperature in production well below threshold from cooled production well, drilling of new horizontal borehole, equipped with later with filter-shank, in direction not covered by development sections, with subsequent pumping of steam into both wells to obtain hydrodynamic connection between barrels and maintain required temperature, steam is pumped through an injection well and products are withdrawn due to steam-gravity drainage through a new production well bore with control of steam chamber state. Threshold temperature is 60 °C or less, before construction of the new horizontal borehole a wedge-deflector is lowered to the production well with a slant directed to the areas not covered by the development; a window is cut in the casing of the production well, through which the new horizontal bore is subsequently drilled. 
     EFFECT: technical result is the creation of a no-accident method of super-viscous oil deposit development at the late stage allowing to construct the new horizontal wellbore from the production well with minimum time expenditures. 
     1 cl
Patent RU-2726191-C1 (RU)
Title: Система обеспечения навигационными данными
Inventor: Vdovin Vladimir Stepanovich
IPC: G01S19/07
Filed: 2019-11-26
Granted: 2020-07-09
Abstract: Изобретение относится к области спутниковой навигации и спутникового позиционирования, а именно к системам, обеспечивающим доступ пользователей к информационным ресурсам, которые могут быть получены от спутниковых навигационных систем. Система обеспечения навигационными данными содержит сеть станций комплекса широкозонного функционального дополнения глобальных навигационных спутниковых систем – СДКМ-КФД, на базе системы дифференциальной коррекции и мониторинга – СДКМ и пользовательских компьютеров, связанные посредством сети Интернет между собой и центром обработки данных. Центр обработки данных обеспечивает функционирование интернет-интерфейса (интернет-портала), включающего картографический интерфейс, доступный с пользовательских компьютеров, обеспечивающий управление применением станций системы СДКМ-КФД в интересах пользователей и связанный с платёжными системами. Обеспечивается управление работой сервис-провайдеров и пользователей с данными и передача пользователям файлов формата RINEX. Использование принципов функционирования систем широкозонной и глобальной дифференциальной навигации позволяет сократить число станций наземной сети для обеспечения глобального охвата. 1 ил.
Patent RU-2749673-C1 (RU)
Inventor: JIA QINGYI
IPC: A21C9/06
Filed: 2018-04-03
Granted: 2021-06-16
Abstract: Изобретение относится к пищевой промышленности. Устройство для изготовления пищевого продукта с начинкой, содержащее корпус (1), имеющий форму перевернутого конуса, наклонный шнек (5), выполненный полым с внутренней полостью и внешним профилем в форме перевернутого конуса, вертикальный шнек (8), первую прижимную кромку (9) и вторую прижимную кромку (10), корпус (1) и наклонный шнек (5) вместе образуют экструзионный формовочный механизм, внутренняя полость наклонного шнека (5) и вертикального шнека (8) вместе образуют подающий механизм для подачи начинки, первая прижимная кромка (9) и вторая прижимная кромка (10) вместе образуют прижимно-разделочный механизм, первая прижимная кромка (9) и вторая прижимная кромка (10) установлены на двух соединительных валах (3) вокруг которых они вращаются, при этом на первой прижимной кромке (9) расположена первая прижимная поверхность (14), в середине которой выполнена разделяющая кромка (15), а на второй прижимной кромке (10) расположена вторая прижимная поверхность (18), в середине которой выполнена разделяющая кромка (16). Пищевой продукт с начинкой, характеризующийся тем, что он приготовлен с использованием вышеуказанного устройства, и содержащий начинку, завернутую в оболочку, причем пищевой продукт запечатывают путем прижатия и разделения двух концов оболочки, и он имеет цилиндрическую форму. Способ приготовления пищевого продукта с начинкой, характеризующийся тем, что его осуществляют на вышеуказанном устройстве, и включающий одновременное прижимание и разделение одного конца оболочки с помощью первой прижимной кромки (9) и второй прижимной кромки (10), выдавливание оболочки путем вращения наклонного шнека (5); заполнение оболочки начинкой; прижимание и разделение другого конца оболочки с помощью первой прижимной кромки (9) и второй прижимной кромки (10), при этом все стадии процесса являются непрерывными. Изобретение позволяет упростить устройство для приготовления изделий с начинкой, а именно, использовать полностью вращательное движение механических компонентов, которые имеют простую сборку, и объединяет экструзионный формующий механизм с механизмом подачи, а также упростить изготовление изделий с начинкой. 3 н.п. ф-лы, 8 ил.
Patent RU-2729963-C1 (RU)
Title: Шумозащитная панель (варианты)
Inventor: SAVKIN DENIS ALEKSEEVICH
IPC: E01F8/00
Filed: 2020-02-07
Granted: 2020-08-13
Abstract: Изобретение относится к средствам защиты населенных пунктов от воздействия на них посторонних акустических шумов. Шумозащитная панель содержит выполненный в виде единой детали корпус, образованный передней рабочей поверхностью, задней поверхностью, одной горизонтальной поверхностью с замковым трапециевидным выступом по всей длине панели и одной горизонтальной поверхностью с замковым трапециевидным пазом по всей длине панели. Звукопоглощающий наполнитель размещен внутри корпуса. Вертикальные торцевые крышки закрывают торцы корпуса. Корпус выполнен из стеклопластика. Передняя рабочая поверхность корпуса выполнена в виде чередующихся горизонтальных радиусных или дуговых выступов и впадин, образованных продольно по всей длине панели. В качестве звукопоглощающего наполнителя использована влагостойкая минеральная вата. Вертикальные торцевые крышки с внешней стороны имеют форму, обеспечивающую плотное их прилегание к стойке экрана. Торцевые крышки имеют выемки или отверстия для отвода влаги из корпуса панели. Технический результат - повышение шумозащитных свойств и надёжности панелей. 2 н. и 5 з.п. ф-лы, 3 ил.
Patent RU-2734707-C1 (RU)
Title: Method for cooling down system of space object operating in vacuum when simulating normal operating conditions
Inventor: ZYABLOV VALERIJ ARKADEVICH
IPC: B64G7/00
Filed: 2020-02-11
Granted: 2020-10-22
Abstract: FIELD: astronautics. 
     SUBSTANCE: invention relates, primarily, to ground-based heat-vacuum testing of space object systems (SOS). Method includes installation of SOS in vacuum chamber with cryo-screen (CS), which is evacuated and SOS is simultaneously chilled down, supplying liquid nitrogen into CS cavity. Prior to the beginning of the SOS tests, the CS is marked by height at the specified intervals, the chamber without SOS is evacuated to the specified pressure and when the CS is filled with liquid nitrogen the temperature (T) CS is fixed at each interval, which is close to T of boiling of liquid nitrogen. Simultaneously, T is measured at the highest point of the CS when the quasi-stationary state is reached. This T is compared with the fixed T CS at different heights - until the CS complete filling. As a result, the variation of T of the upper point of the CS is obtained from the height of its filling with liquid nitrogen. When placing SOS in the chamber, a horizontal projection of its upper point on the marked CS is found. After evacuation of the chamber with SOS, CS is filled with liquid nitrogen only up to the above projection, controlling T at the highest point of the cryo-screen in accordance with the obtained T dependence on height. 
     EFFECT: technical result of invention is reduction of energy and labour costs, reduction of SOS cooling time. 
     1 cl, 1 dwg
Patent RU-2749161-C1 (RU)
Title: Centrifugal apparatus for acclimatisation and night-time rest of cosmonauts in zero gravity
Inventor: Goltsev Aleksandr Gennadevich
IPC: B64G1/60
Filed: 2020-03-10
Granted: 2021-06-07
Abstract: FIELD: engineering. 
     SUBSTANCE: centrifugal apparatus for acclimatization and night-time rest of cosmonauts in zero gravity relates to the area of providing normal life conditions of cosmonauts in zero gravity and constitutes a compact centrifugal apparatus comprised of a rotation shaft with an electrical drive, two rings of different diameters perpendicular to the rotation shaft, located at a distance from each other and rigidly connected to the rotation shaft by diametrical plates, capsules with electric drives for accommodation of cosmonauts inclined relative to the rotation axis of the centrifugal apparatus and located between the rings and symmetrically around the circumference of the rings. The centrifugal apparatus is configured to rotate the capsules with cosmonauts by the electric drives relative to the rings of the centrifugal apparatus, synchronously with the rotation of the centrifugal apparatus but with the direction of rotation opposite to the rotation thereof. Rotation of the centrifugal apparatus creates artificial gravity by the impact of centrifugal force, and the inclination of the capsule with the cosmonaut relative to the axis of rotation of the centrifugal apparatus normalizes the blood and fluid flow in the body of the cosmonaut due to the created pressure gradient (difference). 
     EFFECT: centrifugal apparatus is characterized by artificial gravity impacting the cosmonaut in a natural position for night-time rest. 
     2 cl, 2 dwg
Patent RU-2734734-C1 (RU)
Title: Guiding device of nuclear reactor core melt localization and cooling system
Inventor: Sidorov Aleksandr Stalevich
IPC: G21C9/016
Filed: 2020-03-13
Granted: 2020-10-22
Abstract: FIELD: physics. 
     SUBSTANCE: invention relates to a localized and cooled melt system of nuclear reactor core intended for localization of severe beyond beyond-design accidents, in particular, to device for melt transfer of nuclear reactor core into melt trap. Guide device of nuclear reactor core melt localization and cooling system installed under reactor housing and resting on cantilever truss comprises cylindrical part, conical part with hole made in it, walls of which are coated with heat-resistant and low-melting material and are divided into sectors with power ribs located radially relative to hole. Also provided is a power frame consisting of an outer upper power ring, an outer lower power ring, an inner power shell, an outer upper power shell, medium power shell, divided into sectors by power ribs, outer lower power shell, support ribs, base, upper inclined plate connecting conical bottom, power ribs and medium power shell, lower inclined plate connecting conical bottom, power ribs, middle power shell and outer top power shell. 
     EFFECT: high efficiency of localising and cooling melt of nuclear reactor core due to elimination of failure of guide device due to concentration of impact load in conical part of guide device and single-time ingress of core, fragments of internal devices and bottom of housing of nuclear reactor into melt trap. 
     3 cl, 4 dwg