baber/WOPTO huggingface dataset:
Patent DO-P2011000312-A (DO)
Title: Quimioterapia de neoplasma hematopoyetico
Inventor: CHEDID MARCIO
Filed: 2011-10-11
Abstract: Se provee un método y medicamento para tratar leucemia de linaje mezclado, leucemia de linaje mezclado translocado; leucemia mielogenosa aguda basada en leucemia de linaje mezclado translocado; leucemia linfoide aguda basada en leucemia de linaje mezclado translocado; un trastorno mieloproliferativo crónico no basado en MLL; o leucemia linfoide aguda no basada en MLL.
Patent EC-SP11010847-A (EC)
Title: Métodos para tratar la talasemia
Inventor: HOOD JOHN CHARLES
IPC: A61K31/506
Filed: 2011-02-28
Abstract: En la presente invención se proporciona un método para tratar, mejorar, o retrasar al menos un síntoma de un trastorno sanguíneo genético, por ejemplo, anemia drepanocítica o talasemia, en un paciente que lo necesite, que comprende administrar una cantidad terapéuticamente eficaz de un inhibidor de Jak2. También se proporciona en parte un método para reducir un bazo dilatado en un paciente que padece talasemia, que comprende administrar una cantidad terapéuticamente eficaz de un inhibidor de Jak2.
Patent EC-SP11011311-A (EC)
Title: Composiciones y metodos para terapia prolongada con aminopiridinas
Inventor: BLIGHT ANDREW
IPC: A61K31/52
Filed: 2011-09-08
Abstract: Descritos en la presente se encuentran los métodos y composiciones relacionados con el uso de aminopiridinas, tales como 4-aminopiridina, para uso en una forma terapéuticamente efectiva en pacientes con padecimiento de desmielinización, tal como esclerosis múltiple.
Patent GB-189700644-A (GB)
Title: Improvements in or relating to Station Indicators or Combined Station Indicators and Signalling Mechanism.
Inventor: ELLIOTT THOMAS
Filed: 1897-01-09
Granted: 1897-12-18
Abstract: 644. Elliott, T. Jan. 9. Indicators, station. -Relates to station indicators for railway trains, the apparatus being operated by inclines on the permanent way, and being also applicable for applying the automatic brake during fogs &c., or for operating an audible signal to call the attention of the driver or guard. The names of the stations are marked on the flexible band S<2>, Fig. 4, which is wound from one of the drums S, S' on to the other, and passes round the guide-roller S<3>, so that the name of the next stopping - station is exposed through the aperture Q<1> in the casing. The drums S, S' are geared together and to the pinion T<2> on the shaft U, this shaft being connected through bevel gearing on the shafts P, N' to the shaft I. The shaft I is rotated by pawl and ratchet gearing through the rod G, lever F, and contact shoe C, when the shoe strikes the incline D on the permanent way. A reversing-mechanism, operated through the rod W from the handle X, is provided to enable the band S<2> to be rotated in the reverse direction on the return journey. The drums S, S', and the band S<2> &c., are removable, and can be replaced by others suitable for different journeys.
Patent GB-189703498-A (GB)
Title: A Thread Holding and Cutting Appliance for Attachment to Reels, Spools, and the like.
Inventor: WARD WILLIAM
Filed: 1897-02-10
Granted: 1898-01-22
Abstract: 3498. Ward, W. Feb. 10. Cleats or holders for thread &c. A piece of wire, bent into the form shown, is inserted into the central aperture of a bobbin, spool, &c., and is formed at G into a cleat for holding the loose end of thread and at C with a cutting-edge.
Patent GB-189704333-A (GB)
Title: Improvements in Sweep- or Shaping Sawing and Drilling Machines.
Inventor: VOLTZ CHARLES
Filed: 1897-02-17
Granted: 1897-03-27
Abstract: 4333. Voltz, C. Feb. 17. Sawing; drilling.-In sweep or shaping wood-sawing machines the saw blade is connected by a clamp and a screw thread and nut -with a spindle j formed of two parts connected by a ball-and-socket joint, and connected by links y<11 >to the spiral springs y'. The spindle is guided in the bush l<1> in an adjustable tube r attached to the yoke y, and at the bottom by another bearing-piece. The lower spindle to which the saw is connected is movable in an universal joint, by which it is attached to the connecting-rod of a crank shaft driven by a cord pulley. The saw blade can be turned in all directions by means of a socket-like handle on the tube r. A drill bead may, when desired, be screwed on to the spindle j, and the latter may be rotated by a cord from the above-mentioned pulley passing round a whirl on the socket handle, the downward motion of the drill and spindle being controlled by hand pressure upon a sliding rod temporarily connected with the spindle.
Patent GB-189704744-A (GB)
Title: Improvements in Apparatus for Washing or Leaching Granular or Powdered Substances, and Separating the same from the Liquids used.
Inventor: MOODIE ROBERT
Filed: 1897-02-22
Granted: 1898-05-20
Abstract: 4744. Moodie, R. Feb. 22. Gold ; washing granular materials.-A semicircular tank is divided into cells by partitions adapted to contain a solvent, and the ore or other material is passed from the one to the next by suitable feeders. Figs. 1 and 2 show the arrangement. A tank is divided by partitions into cells a<1>-a<10>, and in each is a stirrer or propeller b<1>-b<10> for transferring the material. These carry scoops at the lower ends, and are mounted on a rocking shaft e. They lift the material to the edge of the partitions, where they engage with scrapers c<2>-c<9> and discharge the material over the edge. Fig. 2 shows the last compartment a<10>, in which the scoop b<10> under the action of the scraper finally discharges the leached material. The material is first placed into a hopper o, whence it passes into the dry cell a<1> through a suitable aperture, and is raised by a scoop b<1>, which is preferably tilted.
Patent GB-189709039-A (GB)
Title: Improvements in Valves for Pneumatic Tyres and other Inflating Articles.
Inventor: HALL ROBERT FREDERICK
Filed: 1897-04-09
Granted: 1898-03-26
Abstract: 9039. Hall, R. F. April 9. Tyres, pneumatic, inflating-valves for. The casing a is bored to receive the tube b, which is screwed to the cap e at b<4>, and its end b<5> forms a seating for the indiarubber valve g resting in the two part carrier h, h<1>. The cap e has four longitudinal slits e<4> and an end perforation e<3> for the passage of the plunger rod f. Light springs f<2> and i bear respectively against the one end of the carrier h, h<1> and the flange f<1> of the rod f. When the inflator is screwed on, the act of pumping causes the valve to move off its seat and allow air to pass by the slits e<4> to the tyre, and as soon as pumping ceases the springs and back - air pressure close the valve.
Patent GB-189711541-A (GB)
Title: An Improved Method of and Means for Propelling Tricycles and other Carriages by Compressed Air, applicable also for Propelling Boats.
Inventor: WILLIAMS DAVID
Filed: 1897-05-10
Granted: 1897-11-20
Abstract: 11,541. Williams, D., and Davies, E. R. May 10. Motor road vehicles.-Consists of means for propelling tricycles and other carriages by compressed air. Fig. 1 shows in plan the application of the invention to a tricycle. The cylinders a of a compressed-air engine, which drives the crank axle d, are supplied with compressed air from the reservoir l. To start the vehicle, the reservoir is filled by means of a pump, which forces in air against the resistance of the spring n acting on the piston m. After the vehicle has started and the reservoir needs replenishing, air is supplied by pumps f, f<1> which are worked from the crank axle d.
Patent GB-189713144-A (GB)
Inventor: FLETCHER WALTER
Filed: 1897-05-27
Granted: 1898-04-09
Abstract: 13,144. Fletcher, W. May 27. Saddles.-The frame is formed of two curved bars A, which come together at B and are connected to a peak-plate D, but are splayed out at the rear and secured to a cantle-plate E. The cover H is formed of soft-cured rubber, and may be provided with flaps I and inflated recesses J ; it may be strengthened at its edges by means of canvas, perforated for ventilation, and cushioned or covered with leather, canvas, etc.; or it may be ribbed or strengthened where necessary, or otherwise modified. The cover is stretched over the frame and secured by lacing or other means.
Patent GB-189721342-A (GB)
Title: Improvements in the Drawing Rollers of Drawing, Roving, and Spinning Machinery.
Inventor: IVES BENJAMIN
Filed: 1897-09-17
Granted: 1898-08-06
Abstract: 21,342. Ives, B. Sept. 17. Rollers for drawing, roving, and spinning machinery. Leather scraps are ground with water into a pulp and moulded by hydraulic or other pressure into a roller, or into sheets or discs A, which are subsequently cemented together to form a roller.
Patent GB-189724915-A (GB)
Title: An Improvement in the Cranks of Bicycles and other Cycles.
Inventor: PENNELL HENRY CHOLMONDELEY
Filed: 1897-10-27
Granted: 1898-03-05
Abstract: 24,915. Pennell, H. C. Oct. 27. Cranks; pedals. -Relates to a crank arrangement for bicycles by which the effective throw of the crank is stated to be increased during certain parts of the stroke. A supplementary arm, plate, or disc carrying the pedal is pivoted to the crank arm, which is fixed to the crank axle. Fig. 1 shows one form of the invention. A disc f is fixed to the crank arm a and a second disc f<1> carrying the usual form of rotary pedal b is mounted to rotate on ball bearings i, j.
Patent GB-189725658-A (GB)
Title: Improvements in Machines for Lasting Boots and Shoes.
Inventor: STIRCKLER ALBERT EDWARD
Filed: 1897-11-04
Granted: 1898-10-22
Abstract: 25,658. Stirckler, A. E. Nov. 4. Lasting.-Relates to improvements on the lasting- machine described in Specification No. 422, A.D. 1896, in which the toe of the last is pushed down into the upper, which is held stationary. In the present machine, the last is fixed while the toe of the upper is pulled up over it and then wiped over. Fig. 1 shows a side elevation of the upper part of a machine, in which the last is clamped between toe and heel heads A, A<2> respectively. The former is pivoted to ablock 2 clamped to a plate 4 by an adjustable spring, which yields to allow the head to rise while the upper is being stretched. The plate 4 is movable on a table 5 to suit the length of the last. The inclination of the head A can be varied to suit any last by means of screws 8 and nuts. The latter bear on springs. The upper is laid over the toe-wipers and gripped by a presser 22 shown in detail in Fig. 8. Pressers of any desired size or shape can be secured to the head 20 of the screw 18, which is adjustable in the link 17 by means of a nut 19. The presser 22 is forced down on the upper by a wedge 29, which is forced in below the link 17 by a lever. A button 25 on a rod 24, passing through the hollow screw 18, rests on the sole of the last, its upper end being under a cam lever 27. By rotating this lever into the position shown in dotted lines, the head A is raised and the upper pulled up over the last. The toe of the upper rests against a spring pad 30, which is easily removable and is capable of movement about a vertical axis to suit a left or right shoe. The sides of the upper are pressed against the last by pads 36 acted on by adjustable springs 40. The wipers 42 are pivoted at 43 to carrier plates 44, so that they can easily be changed to suit a particular last. By means of a lever 51 and the connections shown, the wipers are moved forwards and inwards to lay the upper over the last.
Patent GB-189726087-A (GB)
Title: Improvements in Two-speed Bicycle Gear.
Inventor: BALLOCH GUY RALSTON
Filed: 1897-11-09
Granted: 1898-10-08
Abstract: 26,087. Balloch, G. R. Nov. 9. Driving-mechanism, variable-speed, for bicycles. The hub A, which is mounted to run on ball bearings B, B', is provided internally with toothed rings F, F<1> with which may be caused to gear the wheels G, G<1> to give different speeds. The wheels G, G' are eccentrically mounted on balls H carried by a disc I, which may be slid along the hollow axle E to throw the wheels G, G<1> in and out of gear. Motion is imparted to the wheels G, G<1> from the usual chain-wheel D, which is mounted on the ball bearings E, E<1> and connected to a wheel D<1>, which always remains in gear with internal teeth G<2> on the wheel G<1>. The gearing is varied by moving the disc I along the hollow axle C by means of the longitudinal rod J and a series of bell-crank levers and rods carried along the frame to a lever pivoted on the handle-bar. In a modification, the disc I is fixed and the pinion G always remains in gear with the wheel F. The wheel F' is, however, carried by a sleeve which slides over the extended hub of the chain-wheel, and is provided with clutch-teeth for engaging corresponding clutch teeth on the driving-wheel hub. When the clutch teeth are in engagement the hub rotates at the same speed as the chain-wheel, but when the wheel F<1> is slid into engagement with the wheel G<1> a different speed is obtained.
Patent GB-189727869-A (GB)
Title: Improvements in the Manufacture of Coke, and in Apparatus therefor.
Inventor: BOWING JOHN
Filed: 1897-11-26
Granted: 1898-09-24
Abstract: 27,869. Bowing, J. Nov. 26. Coking.-Relates to the manufacture of coke in the way described in Specification No. 2071, A.D. 1897. The coal is coked in an iron or steel retort a separated from the heating-flue d by a wall b between which and the retort is an annular space c. The sectional area of the flue d is substantially the same as the sum of the areas of the gas inlets e. The retort is provided with a hinged and removable base f. The gases leaving the retort are advantageously conducted into a closed condenser containing coal intended for future treatment.
Patent GB-189801862-A (GB)
Title: Improvements in Slubbing, Intermediate, Roving and like Frames.
Filed: 1898-01-24
Granted: 1899-01-14
Abstract: 1862. Hargreaves, L., Bancroft, J., and Howard & Bullough. Jan. 24. Slubbing, intermediate, and roving frames.-Relates to means for disengaging the mechanism for operating the traverse rails, so that the rails can be raised and lowered by hand. The lifter shaft W is connected with the driven cone by the mechanism shown and a wheel D, which is connected to the shaft of the bevel-wheel B by means of a clutch C', C<2>, which may be placed in or out of gear by means of a link E, eccentric F, and rod G operated by the handle H. Instead of the above arrangement, the carrier-wheel T, between the pinion U and the pinion W<1> on the lifter shaft, may be mounted upon an eccentric bush, which may be rotated so as to raise the wheel out of gear by means of a toothed quadrant or rack operated by a handle.
Patent GB-189808789-A (GB)
Title: Improved Controlling or Regulating Gear for Ship's Telegraphs and other Indicating Instruments.
Inventor: HOWIE JAMES
Filed: 1898-04-15
Granted: 1899-04-15
Abstract: 8789. Howie, J. April 15. Telegraphs, mechanical. - Relates to means for neutralizing the ' back-lash' in the controlling or regulating gear of ships' telegraphs or other indicating - instruments. The pointer is fixed to the hollow cylinder E, which is formed with interrupted screw or cam slots e adapted to receive the lugs f on the nut F. The nut works on the screw D, and is prevented from rotating by the lugs f engaging in slots in the casing C. When the screw D is rotated by the operation of the transmitter, the nut F is moved along the screw, and the lugs f impart an intermittent rotation to the cylinder E, causing the pointer to move with a step-by-step motion from centre to centre of the indications on the dial.
Patent GB-189817903-A (GB)
Title: Improvement in Washing Machines.
Inventor: ISAKSEN JOHAN PETTER
Filed: 1898-08-19
Granted: 1898-10-01
Abstract: 17,903. Isaksen, J. P. Aug. 19. Washing - machines.-The oscillating receptacle A i s supported o n toothed segmental pieces k, l, and is operated by the handle d.
Patent GB-189821649-A (GB)
Title: Improvements in Taking and in Projecting Photographic Images, in Means therefor, and in Photographic Negatives.
Inventor: FRIESE-GREENE WILLIAM
Filed: 1898-10-14
Granted: 1899-10-14
Abstract: 21,649. Friese-Greene, W. Oct. 14. Cameras; producing magic-lantern slides.-Relates to a method of producing negatives by exposing successively through three coloured screens, and then making transparencies from these for projection in a magic-lantern. A rotating screen made up of three coloured sectors representing the three primary colours is rotated rapidly behind the camera lens 7 by means of a belt 12 and pulleys 13 and 11. It is stated that the negative produced will produce a positive transparency which, when placed in a magic-lantern with a similar rotating screen, will project an image in natural colours on the screen. By using lenses made up of three coloured sectors, the threecoloured screen may be dispensed with both in the camera and in the magic-lantern. Lenses built up in this way of uncoloured sectors are used to produce "softened" negatives which do not require retouching.
Patent GB-189823057-A (GB)
Title: Improvements in Disinfecting by Means of Formic Aldehyde.
Inventor: ZIMMERMANN AUGUST
Filed: 1898-11-02
Granted: 1899-09-02
Abstract: 23,057. Zimmermann, A., [Chemische Fabrik auf Actien vorm. E. Schering]. Nov. 2. Disinfecting.-Formic aldehyde mixed with water vapour in a state suitable for disinfecting purposes is obtained by heating a solution of the aldehyde diluted with water to prevent polymerization, e.g., a 40 per cent. solution of the aldehyde is diluted to 8 per cent. The Provisional Specification states that the evaporating-apparatus described in Specification No. 26,667, A.D. 1896, may be used, or a vessel having narrow outlets or tuyeres through which a spraying is effected ; also that the diluent, usually water, may be gradually added from a drop apparatus.
Patent GB-189901318-A (GB)
Title: Submergible Vessels for Raising or Floating Sunken or Grounded Ships.
Inventor: RIEMER HERRMAN GUSTAV
Filed: 1899-01-19
Granted: 1899-03-18
Abstract: 1318. Riemer, H. G., and Riemer, P. O. Jan. 19. Sunken ships &c., raising.-Lifting cylinders or vessels e, divided into compartments by partitions c, d, are sunk by admitting water through pipes s, open at the ends, and are connected together by cables passing under the sunken vessel. Water is pumped out of the chambers through the pipes s, a, while air is admitted through the pipes b, m, in order to raise the cylinders and ship. The pipes m, s are fitted with valves operated by rods passing through stuffing-boxes in the shell of the cylinder. The cables are attached to hooks or rings w, and may be fastened directly to the hull of the sunken ship. In great depths, the water is pumped out by force-pumps driven by electromotors.
Patent GB-189904432-A (GB)
Title: Improvements in Car Brakes.
Inventor: MCCOLLUM JAMES HARRY KEIGHLY
Filed: 1899-02-28
Granted: 1899-04-22
Abstract: 4432. McCollum, J. H. K., Elmsley, R., and Brouse, W. H. Feb. 28. Brakes.-The brake-shoes G are operated by a pivoted lever E connected thereto by a rod G<2> and a bar G'. On pulling a lever V, connected by pivoted levers and rods as shown to a rod M<1> guided by rods N to which a rod M is pivoted, shoes L<1> and L, carried by the rods M' and M, are applied to a sleeve I. The motion of this sleeve being checked, it turns a lever J which engages a recess i therein and is pivoted to a sheave C fixed to the axle. The wings of the lever J now turn a lever K on its pivot k, and apply a shoe K<1> to the inner rim of a ring D<1> secured to a loose strap D which now turns with the axle and through a rope, chain, or the like H turns the lever E. On releasing the lever V, a spring o<2>, acting between two discs o and o<1> secured to rods 0 and O<1>, relieves the brakes. An oil cup l<2> is provided. In a modification, the lever J has a toothed segment to engage teeth on the sleeve I, and its opposite end is adapted to separate the ends of two curved levers pivoted to the sheave C and adapted to engage the inner rim of one of the rings D<1>. In another modification, the rod M' is operated electromagnetically, and the brakes are applied by passing the current and relieved by a spring or vice versÔ. In a further modification, in which the brakes are applied by a draw-bar, the ring D<1> has ratchet teeth on its face and the pawl which engages these teeth, to keep the brakes on, is put out of engagement by a push-rod and levers to release the brakes.
Patent GB-189905463-A (GB)
Title: An Improvement in Guillotine Paper Cutters.
Inventor: SPROULE ROBERT FRITH
Filed: 1899-03-13
Granted: 1900-03-10
Abstract: 5463. Sproule, R. F. March 13. Cutting-machines for paper.-In guillotine machines, the knife slide b and the clamping-slide e are clamped together until the piper is reached, by reason of a bar f on the knife slide being gripped between the bars g and h on the clamp, the bar g being fixed on the clamp, while the bar h is pivoted to it and is held in the position shown by a pair of toggle-levers j, which are at this time in the straightened position. When the pile of paper is clamped with sufficient force, the togglelevers j are operated by a stud x on the bar f, whereby the two slides are released from one another, the knife slide continuing its motion in order to make the cut, while the slide e is clamped to a rod t pivoted to the frame. The rod t passes through a loop in an adjustable stud v, which projects through a lever o, the end of the latter being raised at the proper time by the inclined end of a rod q on the knife slide. When the knife slide is raised, it engages with projections on the clamping-slide, and the two slides rise together until the middle pin of the toggles j is engaged by a fork l on the frame and the slides are automatically clamped together ready for the next cut.
Patent GB-189905576-A (GB)
Title: Improvement in Automatic Systems of Preventing Collisions on Electric Railways.
Inventor: BANCROFT CHARLES FOSTER
Filed: 1899-03-14
Granted: 1899-04-29
Abstract: 5576. Bancroft, C. F., and Sullivan, P. F. March 14. Electric railways arranged on a block system so that the current supply is cut off from adjacent sections and thereby collisions are prevented. Fig. 1 shows an arrangement of a single line with passing places on which the sections t, t' of the conductors, insulated from the rest of the trolley lines T, are connected to or disconnected from the main feeder F by switches S<1>, S<2>, &c. These switches are operated from contacts U, C' at the entrance and exit of each passing place arranged so that, when a vehicle leaves a passing place, it cuts out the conductor on the opposite side in the passing place in front and also the conductor in the section just left, and remakes the circuits when it enters the next place. As an additional safeguard in case vehicles enter two places simultaneously, a third contact C' and switchoperating solenoid N' are provided. The switches consist of pivoted arms 0 with two or three solenoids N, N<1>, M acting on a core pivoted to the arm. The contacts C, C' consist of a plate, flat or preferably of inverted V-section, supported by the hangers over the trolley wire T and touched by the trolley to complete the circuit through the solenoids between the main F and return. This circuit may include lamp signals to show the condition of the conductors.
Patent GB-189912868-A (GB)
Title: Improvements in Sewing Machines.
Inventor: DEARBORN CHARLES ALMY
Filed: 1899-06-20
Granted: 1899-07-22
Abstract: 12,868. Dearborn, C. A. June 20. Crank linkages.- In an overedge blind - stitching sewing-machine, the necessary combination of turning, reciprocating, and rocking motion is imparted to the looper shaft D' from the pin H<1> of an inclined crank G<1> on the main shaft, the shaft D' and pin H<1> being connected by a yoke J<1> and sleeve I<1>.