baber/WOPTO huggingface dataset:
Patent CA-2584873-C (CA)
Inventor: STEIN DAVID A
IPC: A61K48/00
Filed: 2005-11-01
Granted: 2017-04-18
Abstract: The invention provides antisense antiviral compounds and methods of their use and production in inhibition of growth of viruses of the Filoviridae family, and in the treatment of a viral infection. The compounds and methods relate to the treatment of viral infections in mammals including primates by Ebola and Marburg viruses. The antisense antiviral compounds are substantially uncharged morpholino oligonucleotides having: a) a nuclease resistant backbone, b) 15-40 nucleotide bases, and c) a targeting sequence of at least 15 bases in length that hybridizes to a target region selected from the following: i) the AUG  start site region of VP35, as exemplified by antisense compounds SEQ ID NO: 21-26, ii) the AUG start site region of VP24, as exemplified by antisense compound SEQ ID NO:34, iii) the region 85 to 65 base pairs upstream of the AUG  start site of VP24, as exemplified by SEQ ID NO:39, iv) the AUG start site region of polymerase L, as exemplified by antisense compound SEQ ID NO: 17, and v) combinations of (i), (ii), (iii), and/or (iv).
Patent CA-2589637-C (CA)
Title: Materiau de matite aux vibrations du type composite a resine sans chromate, avec liaison a durabilite excellente
Inventor: KADOWAKI NOBUO
IPC: C08K3/36
Filed: 2005-11-29
Granted: 2011-07-26
Abstract: L'invention décrit un matériau amortissant composite en résine dépourvu de chromate ayant une structure multicouche dans laquelle une composition de résine viscoélastique est intercalée entre des plaques métalliques en tant que couche intermédiaire. Ce matériau se caractérise en ce que (i) la composition de résine viscoélastique est une résine thermodurcissable composée d'une résine de polyester copolymérisé amorphe et d'un durcisseur, et (ii) une pellicule de base adhésive dépourvue de chromate composée de 5 à 50 % en poids de silice, 5 à 50 % en poids d'un résine de polyester, de 1 à 50 % en poids d'acide tannique et de 0 à 30 % en poids d'un agent de pontage à base de silane est disposée sur une surface de la plaque métallique qui est en contact avec la composition de résine viscoélastique. Ce matériau amortissant composite de résine dépourvu de chromate offre une adhérence de longue durée excellente.
Patent CA-2590374-C (CA)
Title: Cap for an aerosol container or a spray container
Inventor: EBERHARDT HEIKO
IPC: B65D83/16
Filed: 2005-12-15
Granted: 2010-11-02
Abstract: In order to acoustically seal a spray cap, a cap (7) is provided with a button (6) having an elastic connection (49) between button (6) and cap (7) in order to achieve an acoustic seal (49) of cap (7). In this context, seal (49) is designed as a crimped device. A hinge (5) of button (6) is formed in an analogously crimped manner in order to be able to actuate it together with seal (49) in a smooth-running manner.
Patent CA-2601902-C (CA)
Title: Low density cements for use in cementing operations
Inventor: FRASER MICHAEL R
IPC: C04B28/08
Filed: 2007-09-14
Granted: 2011-07-05
Abstract: A cement mix suitable for blocking or plugging an abandoned pipeline or back filling a mine shaft, tunnel or excavations contains (i) Portland cement or a mixture of at least two components selected from Portland cement, fly ash, slag, silica fume, gypsum, bentonite and limestone; (ii) diatomaceous earth; (iii) zeolite, (iv) an aluminum silicate and (v) an inorganic salt accelerator. The cement mix may further contain an alkali metasilicate and/or alkali silicate. A cementitious slurry, formulated from the cement mix, may have a density less than or equal to 1500 kg/m3, and exhibits good compressive strength.
Patent CA-2606525-C (CA)
Inventor: CHANG STANLEY
IPC: F02K3/04
Filed: 2006-04-19
Granted: 2013-10-22
Abstract: The present invention relates to an air compression type engine for aviation. The conventional aircraft engine is complicated in structure, consumes expensive aero fuel, and produces extremely loud noise during operation.                                                        Therefore, the present invention employs a turbo-charged air compressor to generate high temperature and high pressure gas in the pressure chamber, and uses the reaction thrust force generated by ejecting the compressed air through the nozzle to make the aircraft vertically take off/land, suspend in the air and fly forwardly. Benefited from the simple structure, the manufacture cost of the aircraft engine can be dramatically decreased.                    Vertically raising and landing the aircraft can be achieved by changing the ejection directed of the compressed air in the pressure chamber. The commonly used gasoline or diesel, which is cost saving and capable of combusting with a high combustion value, can be used instead of the expensive aviation kerosene. Further, the generated noise is quite small. By means of above arrangement, it is possible to manufacture a jet type manned craft like a car, which can be operated by common people to vertically take off/land and shuttle conveniently in the downtown area through simple operation procedure.
Patent CA-2608945-C (CA)
Inventor: ATKINS MARTIN PHILIP
IPC: C07C29/153
Filed: 2006-05-18
Granted: 2013-12-17
Abstract: The present invention relates to an improved process for the conversion of carbon oxide(s) and hydrogen containing feedstocks to oxygen containing hydrocarbon compounds in the presence of a particulate catalyst. In particular, the present invention relates to an improved process for the conversion of carbon oxide(s) (CO and CO2) and hydrogen containing feedstocks, e.g. synthesis gas or syngas, to alcohols in the presence of a particulate modified molybdenum sulphide based catalyst, or a modified methanol based catalyst and/or a modified Fischer-Tropsch catalyst.
Patent CA-2613787-C (CA)
Inventor: BURTON SCOTT ANDREW
IPC: F01D9/02
Filed: 2007-12-06
Granted: 2015-08-04
Abstract: A turbine nozzle assembly (50) is provided. The turbine nozzle assembly (50) includes a radially inner band (56), at least one stator vane (52) extending radially outward from the inner band, the stator vane includes an airfoil (53) including a root portion (284) extending from the inner band to a tip portion (282), the airfoil further including at least one lean directional change (174,176,182,184,186) and a plurality of sweep directional changes (196,198,202,204,206) defined between the root portion and the tip portion.
Patent CA-2616561-C (CA)
Inventor: SCHILTZ JIM
IPC: G01N33/531
Filed: 2006-07-25
Granted: 2018-12-18
Abstract: The invention provides for the treatment and prevention of a transmittable viral disease in a mammal. The invention specifically relates to the use of goose antibodies for treating or preventing infection or preventing or limiting one or more symptoms associated with infection by the transmittable viral disease. Administration of such goose antibodies to a mammal can be effective for reducing mortality in a population of subjects that are infected, or become infected, with the disease. The invention also provides kits useful for detecting the presence of transmittable diseases.
Patent CA-2617750-C (CA)
Inventor: ENEVOLDSEN PEDER BAY
IPC: F03D11/00
Filed: 2008-01-10
Granted: 2015-05-05
Abstract: A wind turbine rotor blade (1) with an airfoil (5) having a suction side (13) and a pressure side (15) is provided. The airfoil (5) comprises an inner airfoil portion (7) and an outer airfoil portion (6), where the inner airfoil portion (7) is comparatively thicker than the outer airfoil portion (6) and provided with vortex generators (21). The thickness of the inner airfoil portion (7) is between 30% and 80% of the inner airfoil portion's (7) chord length, and the vortex generators (21) are located at the suction side (13) of the inner airfoil portion (7) between 8% and 12% of the chord length, as measured from the leading edge (9) of the airfoil portion (7). Figure 3
Patent CA-2618099-C (CA)
Inventor: SIMARD J MARC
IPC: A61K48/00
Filed: 2008-02-08
Granted: 2016-09-20
Abstract: The present invention is directed to a combination of therapeutic compounds and treatment methods and kits using the combination. In particular, one of the combination affects the NC ca-ATp channel of neural tissue, including neurons, glia and blood vessels within the nervous system. Exemplary SUR1 and/or TRPM4 antagonists that inhibit the NC ca-ATP channel may be employed in the combination. The combination therapy also employs one or more of a non-selective cation channel blocker and/or an antagonist of VEFG, NOS, MMP, or thrombin. Exemplary indications for the combination therapy includes the prevention, diminution, and/or treatment of injured or diseased neural tissue, including astrocytes, neurons and capillary endothelial cells, that is due to ischemia, tissue trauma, brain swelling and increased tissue pressure, or other forms of brain or spinal cord disease or injury, for example. In other embodiments, there are methods and compositions directed to antagonists of TRPM4, including at least for therapeutic treatment of traumatic brain injury, cerebral ischemia, central nervous system (CNS) damage, peripheral nervous system (PNS) damage, cerebral hypoxia, or edema, for example.
Patent CA-2619960-C (CA)
Inventor: BLACKBURN DAVID R
IPC: E04C2/284
Filed: 2006-08-25
Granted: 2014-11-04
Abstract: A gypsum slurry includes calcium sulfate hemihydrate, water and calcium sulfate dihydrate is coated with a hydrophilic, dispersible coating. The coating is less soluble than the calcium sulfate hemihydrate to delay exposure of the landplaster to the remainder of the slurry, preventing premature crystallization and the early stiffening that accompanies it. Another embodiment is a gypsum slurry that includes calcium sulfate hemihydrate, a polycarboxylate dispersant, water and coated calcium sulfate dihydrate. In this case, the hydrophilic, dispersible coating is selected to serve as a modifier to enhance the ability of the dispersant to fluidize the gypsum slurry.
Patent CA-2625618-C (CA)
Inventor: FINKEN HOLGER GERHARD CLEMENS
IPC: G21C1/07
Filed: 2007-02-08
Granted: 2015-04-14
Abstract: This invention relates to a nuclear plant 10 including a main power system (12) and a fuel handling and storage system (14). The system (14) is connected to a sphere inlet (22) and a sphere outlet (24) of a multi-pass high temperature gas cooled pebble bed reactor (16). The system (14) is configured such that gas flows from the system (14) into the reactor (16) through both the sphere inlet (22) and the sphere outlet (24) thereby inhibiting the ingress of high temperature gas from the reactor into the system (14).  Restricting indexers (66, 68) permit the movement of spheres between the reactor (16) and the system (14) and dampen out the transmission of pressure fluctuations from the power system (12) to the system (14).
Patent CA-2627958-C (CA)
Inventor: OKITA YOJI
IPC: F01D9/02
Filed: 2005-11-01
Granted: 2011-03-22
Abstract: A plurality of film cooling holes 13 is formed at regions exposed to a hot gas in a turbine component main body 3, each of the film cooling holes 13 is comprised of a straight hole portion 15 formed at a portion at a side of an inner wall surface 5a of the turbine component main body 3 and a diverging hole portion 17 formed at a portion at a side of an outer wall surface 5b of the turbine component main body 3, and further each of the film cooling holes 13 is so constituted that an outlet surface 17p of the diverging hole portion 17 from a center portion to both end sides in a lateral direction L3 gradually to a great extent leans toward a downstream side of the hot gas on the basis of a hypothetical plane VP parallel to two directions of an axial center direction L2 and a lateral direction L3 of the straight hole portion 15.
Patent CA-2629068-C (CA)
Title: Appareil et procede de discrimination sensorielle operant a haut debit
Inventor: PALMER R KYLE
IPC: A01K1/03
Filed: 2005-12-06
Granted: 2013-10-15
Abstract: L~invention concerne divers appareils et systèmes utiles dans une discrimination sensorielle. Grâce à l~utilisation d~un plateau d~échantillon multipuits, l~appareil et le procédé d~analyse à haut débit prévoit une discrimination sensorielle rapide d~un grand nombre d~échantillons.
Patent CA-2632634-C (CA)
Inventor: JOHNSON ORREN
IPC: E21B21/12
Filed: 2008-05-26
Granted: 2013-09-17
Abstract: A drive connection for a down hole drilling motor includes a tubular outer housing with an inner mandrel. The outer housing has a motor end, a bit end and defines an interior bore. An angular offset is provided toward the bit end of the outer housing. The inner mandrel, positioned within the interior bore of the outer housing, includes a motor end section, a bit end section and an intermediate section connecting the motor end section and the bit end section. The intermediate section has an upper articulating engagement that is coupled to rotate with the motor end section and a lower articulating engagement that is coupled to rotate with the bit end section. The motor end section, intermediate section and bit end section rotate together, with the upper articulating engagement and the lower articulating engagement accommodating rotation that is offset due to the angular offset.
Patent CA-2636740-C (CA)
Inventor: WEI SU
IPC: A61B3/12
Filed: 2006-12-21
Granted: 2012-06-12
Abstract: A sequential wavefront sensor comprises a light beam scanning module (212) , a sub-wavef ront focusing lens (220) , a detector (222) with more than one photosensitive area and a processor for calculating the sequentially obtained centroids of a number focused light spots from the sub-wavefront s to determine the aberration of the input wavefront. A sequential wavefront sensing method comprises the steps of ; sequentially projecting a number of sub-wavefronts onto a sub-wavefront focusing lens and a detector with more than one photosensitive areas, calculating the centroid of the focused light spot from each sub-wavefront, and processing the centroid information to determine the aberration of the wavefront. In particular, a method for auto-focusing and/or auto-astigmatism-correction comprises the steps of sequentially projecting a number of sub-wavef ronts around an annular ring of a wavefront to a sub-wavefront focusing lens and a detector, calculating the centroid of focused light spot from each sub-wavefront to figure out the centroid trace and hence the defocus and/or astigmatism, adjusting the focus and/or astigmatism of the optical imaging system before the wavefront sensor so that the measured defocus and/or astigmatism is minimized.
Patent CA-2641430-C (CA)
Title: Water plant removal tool
Inventor: VOGEL CRAIG
IPC: A01D44/00
Filed: 2008-09-22
Granted: 2011-07-12
Abstract: A manually operable cutting tool for removing vegetation from a body of water such as along the shoreline of a pond or lake includes a handle and a pair of angularly adjustable cutting blades. The blades are selectively, pivotally adjustable between fully open and fully closed angular positions for ease and safety of handling. An optional floatation bar may be provided for attaching to the blades which allows the blades to be pulled across the surface of the water for collecting floating weeds.
Patent CA-2644347-C (CA)
Inventor: WENGEL JESPER
IPC: C12N15/113
Filed: 2007-03-23
Granted: 2017-05-30
Abstract: An RNA complex for mediating RNA interference is provided that comprisies a core double-stranded region of between 15 to 40 base pairs. The core double stranded region comprises an antisense strand and a discontinuous passenger strand, that is hybridised to the antisense strand, wherein the discontinuity is a nick or a gap of 1 or 2 nucleotides, and wherein the RNA complex comprises Locked Nucleic Acid (LNA) nucleotide analogues that increase the melting temperature of the core double stranded region, and wherein the discontinuous passenger strand comprises a first and a second RNA-molecule, which together form the discontinuous passenger strand and further where the first and second RNA molecules of the passenger strand each comprise at least one LNA unit. The RNA  complex of the invention has therapeutic use and has improved specificity.
Patent CA-2646175-C (CA)
Title: Process for the preparation of water-in-oil and oil-in-water nanoemulsions
Inventor: DEL GAUDIO LUCILLA
IPC: A61K8/06
Filed: 2007-03-28
Granted: 2014-12-02
Abstract: Process for the preparation of a water-in-oil or oil-in- water nanoemulsion wherein the dispersed phase is distributed in the dispersing phase in the form of droplets having a diameter ranging from 1 to 500 nm, comprising: 1) the preparation of a homogeneous water/oil blend (I) characterized by an interface tension lower than 1 mN/m, comprising water in an amount of 30 to 70% by weight, at least two surface-active agents having a different HLB, selected from non-ionic, anionic, polymeric surface-active agents, said surface-active agents being present in such a quantity as to make the blend homogeneous; 2) the dilution of the blend (I) in a dispersing phase consisting of oil or water with the addition of a surface- active agent, selected from non-ionic, anionic, polymeric surface-active agents, the quantity of the dispersing phase and surface-active agent being such as to obtain a nanoemulsion having a HLB different from that of the blend (I) .
Patent CA-2650982-C (CA)
Inventor: SATO HIROMICHI
IPC: H01M8/02
Filed: 2007-06-06
Granted: 2011-10-25
Abstract: Ribs (41a, 43a) are formed on a cathode plate (41) and an anode plate (43) of a fuel cell (10). The ribs (41a, 43a) protrude toward a contact surface of porous members (26, 27), and provided along an outer periphery of the porous members (26, 27) to surround the outer periphery of the porous members (26, 27). The rib (41a) of the cathode plate (41) and the rib (43a) of the anode plate (43) are arranged to face each other when separator (40) and the porous members (26, 27) are stacked on both sides of a power generating portion (20). The power generating portion (20), the porous members (26, 27), and the separator (40) are stacked such that a seal gasket (30) on the power generating portion (20) is partially sandwiched between the ribs (41a, 43a).The perimeter of the porous members ( 26, 27 ) is sealed by an embedded member ( 28, 29) made of, for example, wax materials.
Patent CA-2652988-C (CA)
Inventor: MCCOY ROBERT
IPC: E21B47/00
Filed: 2007-05-17
Granted: 2011-08-02
Abstract: Système, procédé et appareil pour pompe submersible de fond utilisant des capteurs à fibre optique et des capteurs de température répartis sous la pompe submersible dans le but de contrôler la pression et la température de refoulement, la pression et la température d'aspiration, et la température du moteur. Des capteurs de température répartis sont en outre utilisés sous la pompe pour contrôler les perforations dans le puits de forage.
Patent CA-2657887-C (CA)
Inventor: HASCHKE EGGO L
IPC: B65B25/06
Filed: 2007-07-30
Granted: 2014-08-12
Abstract: The invention comprises a system for encasing material in one of a stretchable bag and a shrinkable bag. The system comprises a pair of product horns rotatable in a plane from a first position to a second position; a stretchable-bag system comprising a bag carriage unit; a shrinkable-bag system, comprising a pair of pulling rollers mounted under said product horns and a collection roller mounted adjacent said pulling rollers, the collection roller configured to move a predetermined increment, a product ram configured to move material between the product horns and into one of a stretchable bag and a shrinkable bag, and an air jet for opening the bags.
Patent CA-2661563-C (CA)
Title: Torque transmission assembly for superconducting rotating machines
Inventor: WINN PETER M
IPC: H02K55/04
Filed: 2007-09-13
Granted: 2011-12-06
Abstract: A rotor assembly includes a superconducting winding assembly positioned within a cryogenic region of the rotor assembly. The rotor assembly includes a torque transfer assembly that includes first and second tubes that are positioned in a radial space external to the superconducting winding assembly and that extend along a longitudinal axis of the rotor assembly.
Patent CA-2670569-C (CA)
Title: Snorkel device for flow control
Inventor: MACDOUGALL THOMAS D
IPC: E21B34/06
Filed: 2006-02-02
Granted: 2011-03-29
Abstract: The present invention provides for the operation of a downhole flow control device using a snorkel tube.
Patent CA-2673755-C (CA)
Inventor: LANZAVECCHIA ANTONIO
IPC: A61K39/42
Filed: 2008-01-03
Granted: 2016-04-05
Abstract: Neutralising antibodies which are specific for human cytomegalovirus and bind with high affinity as well as immortalised B cells that produce such antibodies. The antibodies also have a high potency for the neutralisation of infection. Characterization of the epitopes that the antibodies bind to as well as the use of the antibodies and the epitopes in screening methods as well as the diagnosis and therapy of disease.
Patent CA-2675191-C (CA)
Title: Plug protection system and method
Inventor: LANGESLAG RENE
IPC: E21B33/13
Filed: 2009-08-11
Granted: 2012-05-29
Abstract: Disclosed herein is a downhole plug protection system. The system includes, a tubular having perforations in a perforated portion, a screen in fluidic communication with the tubular, a ring in sealable communication with the tubular and attached to the screen the ring having an extended portion positioned radially outwardly of the perforated portion, and a float shoe in fluidic communication with the perforations positionable downhole of the perforated portion.
Patent CA-2677552-C (CA)
Title: Continuously variable transmission
Inventor: SHIN HUYN WOO
IPC: F16H3/02
Filed: 2009-09-03
Granted: 2011-11-15
Abstract: A continuously variable transmission is disclosed, which includes an input shaft receiving a rotational force input from the outside, a plurality of driven gears arranged around the input shaft to have uniform phase differences to receive a driving force from the input shaft, a variable cam varied in its radius of rotation by an external load, a variable input link receiving the rotational force of the input shaft by being rotatably connected to the input shaft, a plurality of one-way clutches receiving bidirectional rotational forces transmitted to the respective driven gears in only one direction, and thereby rotating the driven gears in one direction, a plurality of cam shafts inscribed or circumscribed to the one-way clutches, and a plurality of output links all in the same length, of which one ends are revolved about the rotational center of the variable input link along with the variable cam and the other ends are rotatably connected to the respective cam shafts.
Patent CA-2680148-C (CA)
Title: Surgical stapling apparatus
Inventor: TARINELLI DANYEL
IPC: A61B17/068
Filed: 2008-03-05
Granted: 2015-09-01
Abstract: A surgical stapling apparatus is provided including a cartridge assembly defining a tissue contacting surface; an anvil assembly defining a tissue contacting surface; and a surgical buttress releasably secured to at least one of the tissue contacting surface of the cartridge assembly and the tissue contacting surface of the anvil assembly by at least one anchor. A loading unit is provided including a surgical buttress releasably secured to an anvil assembly and/or a staple cartridge secured thereto by at least one anchor, and a drive assembly including a knife blade, wherein movement of the drive assembly from a proximal position to a distal position results in the knife blade cutting the at least one anchor and freeing each surgical buttress from the anvil assembly and/or cartridge assembly.