baber/WOPTO huggingface dataset:
Patent CA-2631907-A1 (CA)
Title: Substituted pyrrolo-pyrazole derivatives active as kinase inhibitors
Inventor: FANCELLI DANIELE
IPC: A61P35/00
Filed: 2006-12-06
Abstract: Substituted pyrrolo-pyrazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and 5 pharmaceutical compositions comprising them are disclosed;  the compounds of the invention may be useful in therapy in the treatment of diseases associated with dysregulated protein kinase activity, like cancer.
Patent CA-2631996-A1 (CA)
Title: Flash tank refrigerant control
Inventor: HILL FRANK H IV
IPC: F25B49/02
Filed: 2006-12-11
Abstract: A control algorithm is provided for controlling an economizer circuit in a chiller system (100). The control algorithm adjusts the position of a feed valve (114) in the economizer circuit in response to measured system operating parameters to maintain a level of liquid refrigerant in a flash tank (110) of the economizer circuit. The measured system operating parameters can include the load of the compressor (102) and the pressure and temperature of refrigerant in the flash tank.
Patent CA-2632376-A1 (CA)
Inventor: DUCHESNE PERLA
IPC: C07C309/30
Filed: 2008-05-27
Abstract: Provided is a new and improved process for preparing a borated alkaline earth metal toluene sulfonate salt.
Patent CA-2633537-A1 (CA)
Inventor: MICHOS DEMETRIUS
IPC: C01F7/141
Filed: 2006-12-12
Abstract: Alumina particles and compositions containing alumina particles are disclosed.  Methods of making alumina particles and methods of using alumina particles are also disclosed..
Patent CA-2633806-A1 (CA)
Title: Multivolume pipette
Inventor: ROUSSEL BERNARD HENRI JULIEN
IPC: G01N35/10
Filed: 2007-01-05
Abstract: A multivolume pipette (1) is provided. In an exemplary embodiment, the multivolume pipette includes a pipette body (50), a piston (3) disposed within the pipette body, a first chamber (7), a second chamber (8), and a valve F(13). The first chamber and the second chamber are defined at least in part by an inner wall (52) of the pipette body and the piston. The valve is capable of placing the second chamber in fluid communication with an external environment to provide a first volume range of the multivolume pipette. The valve is also capable of placing the second chamber in fluid communication with the first chamber to provide a second volume range of the multivolume pipette.
Patent CA-2640487-A1 (CA)
Title: Devices for selective recruitment, isolation, activation, and/or elimination of various cell populations
Inventor: GEBERT CAROL
IPC: A61F2/06
Filed: 2007-01-31
Abstract: Implantable devices comprise at least one or more targeting molecules that form a primary coating layer for selectively recruiting, isolating, activating, and/or eliminating any cells of interest, such as T cells, monocytes, and stem cells The devices can be utilized for selectively removing a particular subset of cells from a patient Various non-selective pharmaceutical and biological agents can be incorporated into the devices so that cells can be isolated for elimination or for activation/differentiation Cell-type selectivity is conferred by the presence of cell-specific targeting molecules incorporated into the device, preferably at the surface level to permit interaction between the cells of interest and the targeting molecules Related therapeutic methods for utilizing the devices are also provided These devices can be manufactured as stents, catheters, a holding chamber, or any other device, and can be manufactured into any shape, including a conduit, a vessel, and a tubing
Patent CA-2645080-A1 (CA)
Inventor: LEE ROBERT
IPC: A61K9/107
Filed: 2007-03-06
Abstract: The present invention provides a new tri-phasic method for making nanoparticles of poorly soluble active pharmaceutical ingredients
Patent CA-2645901-A1 (CA)
Title: Differential ph probe having multiple reference chambers
Inventor: MOORE LEON EDWARD
IPC: G01N27/333
Filed: 2007-03-16
Abstract: A differential pH probe (150) design uses a container (100) having an outer surface and an inner volume, where the inner volume is divided into a first, a second, and a third chamber. A first pH-sensitive area (101) is located on the outer surface of the first chamber where the first pH-sensitive area (101) is configured to be exposed to a sample. A second pH-sensitive area (104) is located on the outer surface of the second chamber where the second pH-sensitive area (104) is shielded from the sample and is exposed to a first buffer solution. A third pH-sensitive area (108) is located on the outer surface of the third chamber where the third pH-sensitive area (108) is shielded from the sample and is exposed to a second buffer. A first electrode (112) is configured to detect a first voltage across the first pH-sensitive area (101), a second electrode (115) is configured to detect a second voltage across the second pH-sensitive area (104), and a third electrode (114) is configured to detect a third voltage across the third pH-sensitive area (108). Circuitry (120) is configured to process the first voltage, the second voltage, and the third voltage to determine a pH of the sample.
Patent CA-2646575-A1 (CA)
Inventor: NINI DIEGO
IPC: B67D1/04
Filed: 2006-03-22
Abstract: A tap (1) is disclosed for delivering liquids, particularly for delivering high- and medium-density liquids from rigid vessels, comprising: a body (3); stem means (9); and elastic actuating means (11) of the stem 26 means (9); air inlet/outlet means (13, 25, 28) in the body (3) and inside the vessel; valve means (7) for passing air; and non-return valve means (26) placed between the air inlet and outlet means (13, 25, 28) and the vessel interior and adapted to be guided and driven by the pressure difference between outside the tap (1) and inside the vessel.
Patent CA-2648099-A1 (CA)
Inventor: LANGER ROBERT S
IPC: A61K36/14
Filed: 2007-03-30
Abstract: The present invention provides a drug delivery system for targeted delivery of therapeutic agent-containing particles to tissues, cells, and intracellular compartments. The invention provides targeted particles comprising a particle, one or more targeting moieties, and one or more therapeutic agents to be delivered and pharmaceutical compositions comprising inventive targeted particles. The present invention provides methods of designing, manufacturing, and using inventive targeted particles and pharmaceutical compositions thereof.
Patent CA-2648154-A1 (CA)
Title: Procedes et compositions permettant d'obtenir et d'utiliser des complexes multiproteiques a activite biologique
Inventor: FERRANI-KILE KARIMA
IPC: C12M1/34
Filed: 2007-03-30
Abstract: L'invention porte sur des procédés qui permettent d'isoler et d'utiliser des complexes multiprotéiques à activité biologique. Les complexes de l'invention contiennent une ou plusieurs protéines d'intérêt (p.ex., un récepteur, un canal ionique, etc.) et des protéines d'échafaudage associées telles que des phosphatases, des kinases et des composants à densité post-synaptique. L'invention concerne également des tampons ne contenant pas d'agents dénaturants, qui peuvent être utilisés pour isoler les complexes multiprotéiques, et des réseaux de protéines contenant les complexes multiprotéiques précités. Les réseaux de protéines peuvent être utilisés, par exemple, dans des essais de criblage à haut rendement.
Patent CA-2648326-A1 (CA)
Inventor: XIAO ZHEN
IPC: H04L29/08
Filed: 2007-05-03
Abstract: A method and system for streaming media objects. A streaming system include a group of end nodes and at least one core node connected via an overlay network. The end nodes cache segments of media objects and stream the media objects to a client segment by segment. Each end node stores segment indices for locating segments cached on end nodes or a core node in the system. The core node is a dedicated proxy which fetches media objects from a remote media server and streams the media objects to a client when the media objects are unavailable from the end nodes.
Patent CA-2648981-A1 (CA)
Title: Advanced budget bill control system for end users
Inventor: MEYER ANDY
IPC: G06Q50/00
Filed: 2008-12-31
Abstract: A system and method for allowing a consumer of a commodity to set the parameters of a budget bill calculation system via an interactive user interface. The parameters are intended to help consumers control their budget bill calculations, payment structure, true-up factors and other aspects of their budget bills. Budget bill payment amounts are calculated based on historic weather patterns, previous consumption, previous bills, mathematical models or may be set by the consumer art a certain amount, and the parameters selected by the consumer. A budget payment amount is then presented to the user including a budget payment amount and, in some cases, an actual or estimated true-up amount including when and how ant recalculations of the budget amount and true-ups will take place.
Patent CA-2655488-A1 (CA)
Title: Utilisation therapeutique simultanee, separee ou etalee dans le temps d'au moins une neurotoxine botulique, et d'au moins un derive opiace
Inventor: CHABRIER DE LASSAUNIERE PIERRE
IPC: A61K38/48
Filed: 2007-06-11
Abstract: La présente invention a pour objet une composition comprenant : au moins une neurotoxine botulique, et au moins un dérivé opiacé ou son sel. L'invent ion a également pour objet un produit comprenant au moins une neurotoxine bo tulique et au moins un dérivé opiacé ou son sel comme produit de combinaison pour une utilisation thérapeutique simultanée, séparée ou étalée dans le te mps dans le traitement ou la prévention de la douleur ainsi que des désordre s neuromusculaires.
Patent CA-2656291-A1 (CA)
Title: Turbofan engine
Inventor: MUROOKA TAKESHI
IPC: F02K3/06
Filed: 2007-04-06
Abstract: A leading edge portion on the hub side of a fan single-stage bucket (10) for inhaling air is extended longer to the engine front than the tip side and the mid-span. Moreover, the hub side of the fan single-stage bucket (10) is so formed in an integral shape as to have a larger chord length than those of the tip side and the mid-span. Moreover, the base of the hub side leading edge portion has a radius set within the range of a boss ratio of 0 to 0.4.
Patent CA-2656589-A1 (CA)
Inventor: HEMMINGSON ALAN
IPC: G01D3/028
Filed: 2009-02-27
Abstract: A system and method of phase compensating transient performance data are provided. Transient performance data are collected for a plurality of parameters, and two of the parameters are selected. A transfer function is applied to the transient performance data for at least one of the selected parameters to thereby generate phase compensated performance data that is representative of a steady state relationship between the selected parameters.
Patent CA-2659879-A1 (CA)
Inventor: ROBERTSON DIANE
IPC: G06Q40/00
Filed: 2007-07-17
Abstract: The present invention generally provides systems and methods for performing money transfer transactions via a wireless communication device, such as a cellular phone, hi accordance with the invention, the wireless communication device is associated with, or automatically linked to, at least one payment source account {i.e., the wireless communication device is associated with a payment source account that may be automatically charged for payment of account balances, authorized charges, and/or money transfers), hi a preferred embodiment, the wireless communication device is associated with at least one pre- paid payment source account, hi one example, the wireless communication device is a pre- paid cellular phone and/or is associated with a pre-paid money transfer account, hi certain aspects, the wireless communication device may access a pre-directed phone number, e.g., *55, to access a money transfer service provider. Once connected to a money transfer service provider, a user may initiate a money transfer via the wireless device, which is optionally paid to a payee in-person at a money transfer service provider location.
Patent CA-2664852-A1 (CA)
Inventor: KITAGAWA MASAYUKI
IPC: A61K31/787
Filed: 2007-09-27
Abstract: A compound of a resorcinol derivative with a polymer. It is excellent in water solubility and stability and has high antitumor activity even when used in a smaller total drug amount than the resorcinol derivative. The compound of a resorcinol derivative with a polymer comprises a polyethylene glycol structural part, a polymer part having carboxy groups in side chains, and a resorcinol derivative in which a hydroxy group has been bonded to a carboxy group of the polymer part through an ester linkage.
Patent CA-2667232-A1 (CA)
Title: Wireless communication system
Inventor: ODE TAKAYOSHI
IPC: H04W74/02
Filed: 2006-11-01
Abstract: In a wireless communication system comprising a base station and terminals that use a plurality of frequency bands to communicate with each other, each of the terminals determines a wireless channel quality for each of the frequency bands and notifies it to the base station. The base station decides, based on the notification from each terminal, a frequency band to be used by each terminal. The base station then groups the terminals based on the differences or the like of the frequency bands to be used by the terminals, and notifies the terminals of to which terminal groups they belong. Each terminal sets, based on the notification from the base station, the frequency band to be used by that terminal and the terminal group to which that terminal belongs, and determines a wireless channel quality of the notified frequency band to be used. A result of the determination is notified to the base station. The base station performs, based on the wireless channel qualities related to the frequency bands to be used by the terminals, a scheduling for each of the frequency bands to be used, thereby starting communication with the terminals.
Patent CA-2668263-A1 (CA)
Inventor: JONES DALE A
IPC: E21B17/16
Filed: 2009-06-04
Abstract: A monopole acoustic transmitter for logging-while-drilling comprising as a ring that comprises one or more piezoelectric arc segments. The ring is oriented in a plane whose normal is essentially coincident with the major axis of a logging tool in which it is disposed. The ring disposed within a recess on the outer surface of a short, cylindrical insert. The insert is inserted into a drill collar, rather than into the wall of the collar. The ring can comprise a continuous ring of piezoelectric material, or alternately arc segments or active ring segments of piezoelectric ceramic bonded to segments of other materials such as alumina to increase the frequency or heavy metals such as tungsten to reduce the frequency. The material and dimensions of the material used in-between the piezoelectric segments is chosen to alter the frequency of the ring.
Patent CA-2669459-A1 (CA)
Title: Biopsy devices with universal probe
Inventor: HIBNER JOHN A
IPC: A61B10/02
Filed: 2009-06-17
Abstract: A biopsy device comprises a probe that is configured to couple with a holster.  The probe comprises a needle, a cutter, and a body portion. The needle is rotatable and translatable relative to the body portion. The holster has a locking feature that is configured to prevent the needle from rotating relative to the body portion upon coupling of the probe with the holster. The locking feature may also be configured to prevent the needle from translating relative to the body portion upon coupling of the probe with the holster. The same probe may thus be used with a holster intended for use in a fixture-based, stereotactic setting, in which rotation and translation of the needle may be desired; and with a holster intended for use in a handheld, ultrasound-guided setting, in which rotation and translation of the needle may be less desired if not undesirable.
Patent CA-2669520-A1 (CA)
Title: Methods of treating cancer using sirna molecules directed against cd24
Inventor: ARBER NADIR
IPC: A61P37/00
Filed: 2007-11-13
Abstract: A method of treating a CD24-related medical condition is disclosed. The method comprises administering to a subject in need thereof at least one siRNA molecule selected from the group consisting of SEQ ID NO: 1 to 4. Pharmaceutical compositions comprising same are also disclosed.
Patent CA-2670039-A1 (CA)
Inventor: CORVAIA NATHALIE
IPC: C12N5/20
Filed: 2007-11-23
Abstract: The present invention relates to novel isolated antibodies, or the derived compounds or functional fragments of same, capable of inhibiting the proliferation of tumor cells in vitro and/or in vivo, said antibodies having been obtained by functional screening. More particularly, the present invention relates to the 6F4 antibody, specific to the JAM-A protein, as well as its use for the treatment of cancer. Pharmaceutical compositions composed of such antibodies are also covered.
Patent CA-2672100-A1 (CA)
Inventor: STRASSER JOHN
IPC: G06F3/06
Filed: 2007-12-06
Abstract: An apparatus, system, and method are disclosed for solid-state storage as cache for high-capacity, non-volatile storage. The apparatus, system, and method are provided with a plurality of modules including a cache front-end module and a cache back-end module. The cache front-end module manages data transfers associated with a storage request. The data transfers between a requesting device and solid-state storage function as cache for one or more HCNV storage devices, and the data transfers may include one or more of data, metadata, and metadata indexes. The solid-state storage may include an array of non-volatile, solid-state data storage elements. The cache back-end module manages data transfers between the solid-state storage and the one or more HCNV storage devices.
Patent CA-2673259-A1 (CA)
Title: Process for manufacture of nanometric, monodisperse, and stable metallic silver and product obtained therefrom
Inventor: BENAVIDES PEREZ RICARDO
IPC: B22F1/0545
Filed: 2007-04-03
Abstract: The present invention relates to a procedure for preparation by a wet reduction method of nanometric particles of metallic silver, with diameter ranging from 1 to 100 nm and an average diameter of 20 to 40 nm, with monodispersion characteristics, stabilities exceeding 12 months and in a wide range of concentrations. The process comprises 4 stages: a) preparation of the reducing agent solution, taken from the tannins group and preferably tannic acid; b) preparation of a solution of soluble silver salts; c) reaction and, d) liquid-solid separation; the particle size is determined by the nature of the reducing agent and by the pH control of the currents. The final stage is designed for separating and concentrating the material after which the user can prepare the product for integration thereof in the desired medium. The particles obtained are redispersable in different media, such as water, alkidalic and phenolic resins, nitrocellulose, polyeurethane, vinylics, acrylics, alcohols, and in a wide range of organic and polymeric products such as high and low density polyethylene, Nylon, ABS and/or mixtures thereof.
Patent CA-2677268-A1 (CA)
Inventor: GERL STEFAN
IPC: B02C17/18
Filed: 2008-01-04
Abstract: The invention relates to a vertical grinding mill, comprising a closed vertical milling container (1), in which a screw conveyor (2) is arranged so that it can be rotationally driven, conveying grinding bodies (17) to the top. The package of grinding bodies (17) adjusts itself during operation such that the surface (29) thereof is configured to slope radially outward and downward and to end in the region of the bottom edge (18) of an outlet for grinding material (11). Gas is introduced into the milling container (1) above the package of grinding bodies. The gas and grinding material (22) is removed from the milling container (1) via the outlet for grinding material (11).
Patent CA-2680117-A1 (CA)
Inventor: CONETE ERIC
IPC: F01D25/24
Filed: 2008-04-03
Abstract: According to the invention, in order to assemble two parts (154, 162) made of materials having different thermal expansion coefficients at their edge portions (154a, 162a) and engaged with each other, the method comprises forming along the thinned edge of one of the parts tabs (170) separated by slots (172) and obtained by cutting or machining the material of the part, and assembling the parts by attaching them (174) to the tabs. The edge portions are mutually engaged in order to be brought into mutual substantially tight contact at the high temperatures achieved during operation. The invention can particularly be used for assembling parts respectively made of a metal and a ceramic-matrix composite material, in particular in an aircraft gas turbine such as the upstream and downstream secondary nozzles.
Patent CA-2681974-A1 (CA)
Title: Bispecific antibodies and methods for production thereof
Inventor: PARREN PAUL
IPC: C07K16/46
Filed: 2008-03-28
Abstract: The invention relates to an ex vivo method for the generation of a bispecific antibody, comprising the steps of:  a) providing a first antibody having a first binding specificity, wherein said first antibody comprises an IgG4-like CH3 region, b) providing a second antibody having a second binding specificity which differs from said first binding specificity, wherein said second antibody comprises an IgG4-like CH3 region, c) incubating said first and second antibodies together under reducing conditions which allow the cysteines in the core hinge region to undergo disulfidebond isomerization, and d) obtaining a bispecific antibody.  The invention furthermore relates to bispecific antibodies obtainable by the method of the invention.
Patent CA-2682352-A1 (CA)
Title: Multi-led ophthalmic illuminator
Inventor: ARTSYUKHOVICH ALEX
IPC: A61F9/00
Filed: 2008-03-04
Abstract: An ophthalmic endoilluminator has a power supply coupled to a light source, a controller, a collimation device, an alignment device, a lens, and an optical fiber. The light source has three light emitting diodes. Each of the three light emitting diodes produces a different color light. The controller controls the operation of the three light emitting diodes. The collimation device collimates the light produced by at least one of the light emitting diodes. The alignment device aligns the light individually produced by the three light emitting diodes into a single light beam. The lens focuses the single light beam. The optical fiber for carries the single light beam.
Patent CA-2683921-A1 (CA)
Title: Protective shelter
Inventor: HESELDEN JAMES
IPC: E04H9/10
Filed: 2008-04-18
Abstract: A protective shelter that can provide protection within a war zone and which can be readily assembled in a readily assembled in a quick, secure and reliable manner. The shelter is formed of opposite outer walls and a roof structure extending therebetween, wherein the roof structure comprises a plurality of tray members supported by beam supports and in which the plurality of tray members is arranged to receive earth, sand or aggregate material so as to provide a first layer of protection via the roof structure. The tray members can be supported by beams serving to define a shallow arch across the shelter such that the internal height of the shelter centrally, and away from the opposite walls, is greater than the height of the said walls.
Patent CA-2687500-A1 (CA)
Inventor: BRUECK SANDRA
IPC: A61K9/36
Filed: 2008-06-12
Abstract: The present invention relates to a process for the preparation of a medicament comprising vardenafil hydrochloride trihydrate in solid form, in which vardenafil hydrochloride trihydrate is processed with suitable pharmaceutical auxiliaries at a temperature of from about 20°C to about 45°C.
Patent CA-2688636-A1 (CA)
Inventor: DECKMAN HARRY W
IPC: B01D53/56
Filed: 2008-05-16
Abstract: The adsorption of CO2 from flue gas streams using temperature swing adsorption. Adsorbent contactors are used in the temperature swing adsorption unit that contain a plurality of substantially parallel channels comprised of or coated with an adsorbent material that is selective for adsorbing CO2 from flue gas.