Patent SG-11201810466P-A (SG)
Title: Compositions and methods related to engineered fc constructs
Inventor: BOSQUES CARLOS J
IPC: A61K39/395
Filed: 2017-05-23
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property IIIII1H1110111010101111101011111001010111111001111110011111111101111011111 Organization International Bureau (10) International Publication Number (43) International Publication Date ......0\"\" WO 2017/205434 Al 30 November 2017 (30.11.2017) WIPO I PCT (51) International Patent Classification: Clarendon Avenue, Somerville, Massachusetts 02144 (US). A61K 39/395 (2006.01) A61P 37/00 (2006.01) SCHULTES, Birgit C.; 12 Monadnock Road, Arlington, A61K 47/48 (2006.01) C07K 16/46 (2006.01) Massachusetts 02476 (US). (21) International Application Number: (74) Agent: MEIKLEJOHN, Anita L.; Fish & Richardson PCT/US2017/034084 P.C., P. 0. Box 1022, Minneapolis, Minnesota 55440-1022 (22) International Filing Date: (US). 23 May 2017 (23.05.2017) (81) Designated States (unless otherwise indicated, for every (25) Filing Language: English kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, (26) Publication Language: English CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, (30) Priority Data: DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, 62/340,322 23 May 2016 (23.05.2016) US HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, 62/443,451 06 January 2017 (06.01.2017) US KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, (71) Applicant: MOMENTA PHARMACEUTICALS, INC. PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, [US/US]; 675 West Kendall Street, Cambridge, Massachu- SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, setts 02142 (US). TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (72) Inventors: BOSQUES, Carlos J.; 40 Brattle Street, Apt. (84) Designated States (unless otherwise indicated, for every _ 7, Arlington, VMA 02476 (US). HUSTON, James S.; kind of regional protection available): ARIPO (BW, GH, 5 Drew Road, Chestnut Hill, Massachusetts 02167 (US). GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, = LANSING, Jonathan C.; 220 Woburn Street, Reading, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, Massachusetts 01867 (US). LING, Leona E.; 45 Fells TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, = Road, Winchester, Massachusetts 01890 (US). MEADOR EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, — III, James; 38 Gryzboska Circle, Framingham, Massachu- MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, — setts 01702 (US). ORTIZ, Daniel; 15 High Street, Stone- ham, Massachusetts 02180 (US). RUTITZKY, Laura; 70 (54) Title: COMPOSITIONS AND METHODS = FIG. 2 = = = = = = 214 = = = = — 1-1 71- en 71- in 0 = RELATED 202 204 TO ENGINEERED 206 (Fc construct 212 4) I FC --210 08 CONSTRUCTS 216 ei IN 1-1 C:::: ) (57) : The present invention relates to engineered IgG ei Fc constructs and uses thereof. C [Continued on next page] WO 2017/205434 Al MIDEDIMOMOIDEIROIDEMODIMIRINIMIOMMEHOIMIE TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(11)) — as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) Published: — with international search report (Art. 21(3))