baber/WOPTO huggingface dataset:
Patent CA-2462442-A1 (CA)
Title: Alkyne matrix metalloproteinase inhibitors
Inventor: BUNKER AMY MAE
IPC: C07C311/46
Filed: 2002-08-02
Abstract: A compound of Formula (I) or a pharmaceutical acceptable salt thereof, or a tautomer thereof, wherein G1, G2, and B are as defined in the application, a re selective inhibitors of MMP-13. The compounds are useful for treating diseas es mediated by MMP-13, including cancer and arthritis.
Patent CA-2463667-A1 (CA)
Inventor: TOKUHARA EIJI
IPC: B62D65/00
Filed: 1999-10-14
Abstract: A method for repairing a sheet metal (14) of a car body (10), which comprises the steps of removing a damaged part, bending a portion near the end part of a repair member (22) with a sheet-metal repair tool, and bonding the portion near the end part of the repair member to a portion near the end part of the sheet metal (14) in place of the removed part.
Patent CA-2465268-A1 (CA)
Inventor: ZHANG GONGYI
IPC: C07K14/705
Filed: 2002-10-24
Abstract: Disclosed are TALL-1 and TALL-1 receptor protein homologues (agonists and antagonists) designed based on the three-dimensional structure of sTALL-1, eBCMA and eBAFF-R; agonist homologues of APRIL; methods of using wild-type APRIL to inhibit the activity of TALL-1; compositions comprising such homologues, nucleic acid molecules encoding such homologues, and therapeutic methods of using such compounds and compositions. Also disclosed are crystalline complexes of sTALL-1 and sTALL-1 in complex with either BCMA or BAFF-R; models of three-dimensional structures of such crystalline complexes and related structures, methods of drug design using any portion of such structures; methods of design and/or identification of regulatory peptides derived from the such structures; compounds identified by drug design using such structures; and the use of such compounds in therapeutic compositions and methods.
Patent CA-2465317-A1 (CA)
Inventor: RAJANIEMI SAULI
IPC: D21G1/02
Filed: 2002-11-21
Abstract: A sealing structure for the clutch/bearing housing of a roller or roll, said housing comprising one or more outward gaps (5c), wherein the housing is provided with a guard ring (13) placed in the gap (5c) in a position parallel to the roller shell and/or with radial sealing parts (12) fitted against the bearings and/or against the wall of the clutch space, said sealing parts being provided with O-rings (14) or equivalent sealing parts of sealing material fitted at their edges, thus preventing grease and firt from getting from the clutch space onto the product itself and/or onto the shell of the roller or roll.
Patent CA-2468557-A1 (CA)
Title: Package for electro-optical components
Inventor: MA EUGENE Y
IPC: H01L33/62
Filed: 2002-11-27
Abstract: An optoelectronic device including a header (108) having an upper surface and including a plurality of conducting pins (116) extending up through the upper surface; an optical device (102); a tunable optical filter (100), wherein the optical device and the tunable optical filter are arranged in a vertical stack mounted on and extending above the upper surface of the header and wherein the tunable optical filter is electrically connected to the plurality of conducting pins; and a cap (110) affixed to the header and along with the header defining a sealed interior containing the optical device and the tunable optical filter, wherein the cap has a top surface with a window (106) formed therein, and wherein the window is aligned with the tunable optical filter and the optical device. Applications include a three-port add-drop multiplexer.
Patent CA-2469178-A1 (CA)
Inventor: KIM BYUNG JIN
IPC: G11B20/10
Filed: 2003-10-11
Abstract: Le support d'enregistrement comprend une zone de données stockant au moins des flux graphiques multiples dans au moins une partie de celle-ci. Les flux graphiques multiples sont multiplexés et chaque flux graphique est un flux de transport stocké sous la forme d'un ou de plusieurs paquets. Chaque paquet présente un identifiant de paquet et les paquets du même flux graphique ont le même identifiant de paquets.
Patent CA-2469572-A1 (CA)
Inventor: DUNN-COLEMAN NIGEL
IPC: C12Q1/6895
Filed: 2002-10-30
Abstract: La présente invention concerne une nouvelle séquence d'acides nucléiques de l'endoglucanase, appelée egl8, et la séquence correspondante d'acides aminés d'une protéine de cellulase isolée nommée EVGIII. Cette invention a aussi pour objet des vecteurs d'expression et des cellules hôtes renfermant une séquence d'acides nucléiques codant EVGIII, des protéines recombinantes EVGIII, et leurs méthodes de production.
Patent CA-2469765-A1 (CA)
Inventor: GROSS RICHARD A
IPC: B65D47/24
Filed: 2002-11-08
Abstract: A dispensing system (30, 30A) is provided for dispensing a product from a container having an opening. The dispensing system (30, 30A) includes a spout (38, 38A) for communicating with the container opening. The spout (38, 38A) defines at least one discharge aperture (46, 46A) and a distal seal (54, 54A). A nozzle assembly (60, 70, and 80; 60A, 70A, and 80A) is mounted on the spout (38, 38A) for movement between a retracted, closed position and an extended, open position. The nozzle assembly (60, 70, and 80; 60A, 70A, and 80A) includes a nozzle (60, 60A) having a dispensing passage (86, 86A) around at least a portion of the spout (60, 60A). The nozzle assembly (60, 70, and 80; 60A, 70A, and 80A) also includes a resiliently flexible valve (70, 70A) that is sealingly disposed across the nozzle dispensing passage (86, 86A) at a location distally of the spout (60, 60A) and has an initially closed dispensing orifice (132, 132A) which opens in response to a pressure differential acting across the valve (70, 70A). The nozzle assembly (60, 70, and 80; 60A, 70A, and 80A) also includes a flow restrictor (80 and 160; 80A and 160A) below the valve (70, 70A), and a distal seal (96, 96A) for sealingly engaging the spout distal seal (54, 54A).
Patent CA-2472867-A1 (CA)
Inventor: DISALVO ANTHONY L
IPC: A61F13/15
Filed: 2004-06-29
Abstract: An enhanced embossing pattern of an absorbent article having a substrate that has at least one embossed area and one unembossed area, wherein the embossed area has at least two sidewalls and a floor and a coating deposited in the embossed area, wherein the coating imparts visual contrast between the embossed area and the unembossed area of the substrate.  Also included are related methods of making such absorbent articles.
Patent CA-2473337-A1 (CA)
Title: Polymorphisms of the 5' region of the human 5-ht1a gene, associated proteins of the 5' region and a diagnostic test for major depression and related mental illnesses
Inventor: LEMONDE SYLVIE
IPC: C12N15/12
Filed: 2004-07-09
Abstract: Clinical response to antidepressant compounds correlates with a selective down-regulation of presynaptic 5-HT1A receptors in serotonergic raphe neurons.  Thus regulation of the 5-HT1A receptor gene could play a crucial role in the treatment or etiology of major depression. The promoter and repressor activities of the human 5-HT1A receptor gene have been examined. The analysis of the 5'-flanking regions of the 5-HT1A receptor gene has revealed a segment located between about -3438 and about -393 bp upstream from the initiator ATG that mediates cell-specific repression of the gene that is greater in cells that do not express the 5-HT1A receptor. The sequence of part of this region in patients with major depression was examined and a polymorphic C-G change located at -1019 bp (numbered earlier as -1017) was identified, which is associated with major depression. Thus, this sequence can be used as a genetic marker for major depression and related mental illnesses. Proteins that bind to the DNA at the -1019 locus have been identified. Such proteins that bind to this DNA region, for example the transcription factors NUDR/DEAF-1/suppressin and HES-5, are important targets for the development of therapeutic compounds for the treatment of major depression and related mental illness that involve the serotonin system. In addition the promoter region from about -393 to the initiator ATG displays glucocorticoid-mediated repression.
Patent CA-2473895-A1 (CA)
Inventor: VON SPRECKELSEN HENNING
IPC: B65B1/00
Filed: 2003-01-16
Abstract: A closure for a container comprises a spout (22) containing a plastics coated foil (40) that is welded via one face to an inside flange (30) of the spout (22) and by means of a depending portion (42) on its opposite face to a side wall (10) of the container so that forces on the weld between foil portion (42) and the container when the closure is opened are in sheer rather than in tension. The closure can be used with a PET bottle or with other types of plastics or plastics coated containers.
Patent CA-2474509-A1 (CA)
Inventor: DROOG ERIK
IPC: G01N33/543
Filed: 2003-02-14
Abstract: The enumeration of cells in fluids by flow cytometry is widely used across many disciplines such as assessment of leukocyte subsets in different bodily fluids or of bacterial contamination in environmental samples, food products and bodily fluids. For many applications the cost, size and complexity of the instruments prevents wider use, for example, CD4 analysis in HIV monitoring in resource-poor countries. The device, methods and algorithms (Fig. 1) disclosed herein largely overcome these limitations and can be used in remote location.  Briefly, this invention includes the techniques for labeling the fluorescent cells in biological sample and counting the magnetically selected fluorescent cells in the biological sample.
Patent CA-2474721-A1 (CA)
Inventor: ISHII YUTAKA
IPC: C07D453/04
Filed: 2003-01-31
Abstract: A method for kinetic optical resolution of carboxylic acid derivatives with a specific optically active catalyst is provided which comprises reacting a racemic or diasteromeric mixture of a carboxylic acid derivative of the general formula (A) with a nucleophile in the presence of an optically active catalyst to form an optically active nucleophile derivative of the general formula (B). The catalyst is selected from among optically active compounds represented by the general formulae (C) and (D) [wherein R1 is a substituted or unsubstituted, saturated or unsaturated, and linear, branched, or cyclic aliphatic hydrocarbon group which may have a heteroatom; R2 is ethyl or vinyl;  and R5 is hydrogen or methoxy].
Patent CA-2476047-A1 (CA)
Inventor: DONALDSON TIMOTHY A
IPC: A61B19/00
Filed: 2004-07-29
Abstract: A tracking array for attachment to an object in a surgical environment includes tracking elements detectable by a surgical navigation system to permit tracking of th e object.
Patent CA-2477035-A1 (CA)
Title: Protein biomarkers that distinguish prostate cancer from non-malignant cells
Inventor: WRIGHT GEORGE L JR
IPC: G01N33/574
Filed: 2003-02-20
Abstract: This invention provides organic biomolecule markers (e.g., proteins) useful for differentiating prostate cancer, prostate intraepithelial neoplasia or benign prostate hyperplasia, from a negative diagnosis (i.e. normal and beni gn prostate epithelial cells).
Patent CA-2481527-A1 (CA)
Title: Desulfurization and sorbents for same
Inventor: BARES JOSEPH E
IPC: B01J20/06
Filed: 2002-12-03
Abstract: Attrition resistant, sorbent compositions for the removal of elemental sulfur and sulfur compounds, such as hydrogen sulfide and organic sulfides, from cracked-gasoline and diesel fuels are prepared by the impregnation of a sorbent support comprising zinc oxide, expanded perlite, and alumina with a promoter such as nickel, nickel oxide or a precursor of nickel oxide followed by reduction of the valence of the promoter metal in the resulting promoter metal sorbent support composition.
Patent CA-2483248-A1 (CA)
Title: Anastomosis wire ring device
Inventor: ORTIZ MARK S
IPC: A61B17/115
Filed: 2004-09-30
Abstract: An anastomotic ring device for forming a hollow rivet (ring) attachment between tissue lumens facilitates laparoscopic or endoscopic implantation by including features that facilitate actuation from a stressed, generally cylindrical shape. Economica l manufacturer is achieved by weaving open ended strands into a generally cylindrical stent shape that is imparted with a Shape Memory Effect (SME) to actuate to a hollow rivet (ring ) shape. Alternatively or in addition to SME inherent in the woven strands, an actuating force may be received from a helical spring element incorporated into the ring. Self- actuating ring devices are enhanced by forming woven strands into petals that diverge from opposing petals such that the strands encounter less friction when actuating. Each of these features alone or in combination enhance clinical use of anastomotic ring devices, such as a bariatric gastric bypass procedure.
Patent CA-2483331-A1 (CA)
Title: Gastric band introduction device
Inventor: BYRUM RANDAL T
IPC: A61F2/04
Filed: 2004-09-30
Abstract: A surgical tool for safely introducing a gastric band into a patient's abdomen is provided. The instrument includes an inner rod slidably and coaxially disposed within a support tube. The inner rod includes a gastric band releasably secured thereon. Distal movement of the inner rod into the support tube exposes said gastric band.
Patent CA-2484189-A1 (CA)
Inventor: COOK CHARLES MICHAEL
IPC: C07K14/81
Filed: 2003-05-02
Abstract: L'invention concerne des composés inhibant l'angiogenèse qui comprennent un noyau inhibiteur de MetAP-2 couplé à un peptide, et des compositions pharmaceutiques renfermant lesdits composés et un excipient pharmaceutiquement acceptable. L'invention concerne aussi des méthodes permettant de traiter une maladie angiogénique, p. ex. un cancer, chez un sujet, par l'administration à ce sujet d'une quantité thérapeutiquement efficace d'un ou de plusieurs de ces composés inhibant l'angiogenèse.
Patent CA-2485264-A1 (CA)
Title: Formulations useful in the treatment of male and female impotence
Inventor: BOMBARDELLI EZIO
IPC: A61K36/00
Filed: 2003-04-30
Abstract: Disclosed are pharmaceutical compositions containing: extractsof Tribulus terrestris, Turnera diffusa and Cinnamon cassia in the weight ratio of 1.5-3 .5 : 1-2 : 0.1-0.4 respectively; Ginkgo biloba extract, and optionally arginine or a physiologically equivalent esters salts or precursor thereof. The compositions according to the invention are useful in the treatment of male and female sexual dysfunctions.
Patent CA-2486588-A1 (CA)
Inventor: PEDRENO GARCIA MARIA DE LOS AN
IPC: A61P31/04
Filed: 2003-01-21
Abstract: The invention relates to a method for the production of resveratrol in cell cultures. The inventive method consists in: incubating a culture of cells which produce resveratrol naturally, in suspension, in the presence of randomly-methylated .beta.-cyclodextrin (RMBCD) with a degree of substitutio n of between 11 and 13 under conditions that allow resveratrol synthesis and t he excretion of same into the culture medium; and, if desired, isolating the resveratrol produced from said culture medium. The resveratrol can be used i n the production of pharmaceutical or nutraceutical products.
Patent CA-2488291-A1 (CA)
Inventor: MORALES ERIC C
IPC: B65G51/02
Filed: 2004-11-24
Abstract: A conveyor device for conveying a chain of air-filled packing pillows to a selected position includes a generally upstanding duct, a support for supporting the device on a surface, and a pump positioned adjacent to the surface for supplying air to the device. The duct has an air inlet end connected in fluid communication with the pump, an outlet end, and an entrance aperture positioned downstream from the pump and the air inlet end for receiving the chain of air-filled packing pillows. When the pump is activated and the chain of air-filled packing pillows is inserted through the entrance aperture, the chain of air-filled packing pillows is conveyed upwardly through the duct in a longitudinal direction relative to the chain, and directed to arrive at the selected position.
Patent CA-2488322-A1 (CA)
Title: Earthen retaining wall having flat soil reinforcing mats which may be variably spaced
Inventor: HILFIKER HAROLD K
IPC: E02D29/02
Filed: 2004-11-22
Abstract: A soil reinforced wall earthen retaining wall for an earthen formation is provided by embedding planar soil reinforcing mats in the formation at vertically spaced intervals and securing face mats between the soil reinforcing mats. The face mats comprise welded wire gridworks having upper and lower portions engaged behind wires of the soil reinforcing mats which extend across the face of the formation. In one embodiment the face mats comprise paired separate face mat elements secured one above the other in edge-to-edge relationship and intermediate stabilizing anchors are embedded in the formation to hold the face mat elements in vertical alignment. In the paired face mat element embodiment, the lifts of soil between successive soil reinforcing mats are compacted in stages corresponding to the depth of the face mat elements. Bowing of the face mat elements by compression as the result of settling of the formation is prevented by supporting the soil reinforcing mats on the face mats through compressible members and/or supporting the lower edges of the face mats in spaced relationship to the reinforcing mats therebelow by frangible support members.
Patent CA-2488671-A1 (CA)
Title: Methods of sealing expandable pipe in well bores and sealing compositions
Inventor: BROTHERS LANCE E
IPC: C09K8/42
Filed: 2003-06-17
Abstract: The present invention provides methods and compressible foamed sealing compositions for sealing expandable pipe in well bores. The compressible sealant compositions for sealing expandable pipe are basically comprised of a hydraulic cement, a rubber latex, a rubber latex stabilizer, a gas and mixture of foaming and form stabilizing surfactants.
Patent CA-2493819-A1 (CA)
Inventor: BERTI DOUGLAS A
IPC: C08F6/04
Filed: 2003-08-07
Abstract: La présente invention concerne un dispositif et un procédé permettant d'extraire des matières volatiles présentes dans un polymère en masse de transformation. Le dispositif comprend une station multichambre d'extraction de matières volatiles renfermant des premiers et seconds collecteurs. Dans un mode de réalisation, l'invention concerne un procédé consistant à faire passer le flux de polymère en masse de transformation d'une station de polymérisation à une première station d'extraction de matières. On fait ensuite passer le flux de polymère de ladite première station à la station multichambre d'extraction de matières volatiles. Ce dispositif et ce procédé permettent d'obtenir un polymère renfermant moins de 100 ppm de matières volatiles.
Patent CA-2493910-A1 (CA)
Title: Process for increasing the yield of lipid and omega-3 fatty acid in seaweed culture
Inventor: BOURGET EDWIN
IPC: C12P7/64
Filed: 2003-07-22
Abstract: The present invention relates to a new method for producing polyunsaturated fatty acids from algae. The method comprises the step of applying at least growth-limiting factor to an algae culture, causing growth arrest of said algae culture and production and stocking by algae in culture of polyunsaturated fatty acids.
Patent CA-2494361-A1 (CA)
Title: Hot melt tts for administering rotigotine
Inventor: WOLFF HANS-MICHAEL
IPC: A61K31/381
Filed: 2003-07-29
Abstract: The invention relates to a transdermal therapeutic system (TTS) which contai ns a rotigotine-containing adhesive layer and is characterized by the fact that the adhesive layer contains a hot-meltable contact adhesive. The invention also relates to the use of rotigotine for producing the adhesive layer of a TTS in a hot melt method, and a method for producing such a TTS.
Patent CA-2496138-A1 (CA)
Title: Retrofittable mixing valve and method of assembly
Inventor: PINETTE THOMAS C
IPC: F16K11/076
Filed: 2005-02-07
Abstract: A mixing valve cartridge assembly for a spherical mixing valve. The spherical mixing valve has a stem extending therefrom through a support element that embraces a portion of the spherical mixing valve. A keeper secured to the stem so acts with a caming surface to define the range of movement for the stem and to fixture the spherical mixing valve to the support element.
Patent CA-2497311-A1 (CA)
Title: Furrow closer
Inventor: STOKES RICK
IPC: A01B5/00
Filed: 2005-02-16
Abstract: A furrow closer apparatus for attachment to a shank of a ground working implement, the shank extending rearward and downward from an implement frame member, comprises a bracket adapted for attachment to the shank. The bracket extends down from an upper forward portion of the shank. Spring arms extend from the bracket rearward and downward on each side of and below the shank, and are biased to a neutral position. Soil moving elements are attached to the spring arms near the lower end of the shank. Leading faces of the soil moving elements are oriented at opposed angles to the travel direction such that forward portions thereof are farther apart than rearward portions and such that soil contacted by each face is moved toward the shank rearward of the shank.      Rotatable discs with a twine cutter can provide the soil moving elements.
Patent CA-2499105-A1 (CA)
Title: Antimicrobial 1-aryl dihydropyridone compounds
Inventor: PATEL DINESH VINOOBHAI
IPC: C07D413/10
Filed: 2003-10-03
Abstract: The present invention provides antibacterial agents of formula (I), or a pharmaceutically acceptable salt thereof, wherein A is a structure (i), (ii) , (iii) or (iv); X is (a) NHC(=O)R1, (b) NHC(=S)R1, (c) NH-het1, (d) O-het1, ( e) S-het1, or (f) het2.
Patent CA-2501490-A1 (CA)
Title: Methode et systeme de synchronisation d'informations d'identite
Inventor: HACHERL DONALD J
IPC: G06F17/30
Filed: 2004-07-29
Abstract: L'invention porte sur un système d'identité et sur un procédé qui stocke des informations d'identité liées à différents mandants et stocke les identités sur différents systèmes de sorte que ceux-ci puissent utiliser les identités. Un processus de synchronisation synchronise les informations d'identité et des règles sur la base d'une information d'identité (320) un système informatique primaire et un système informatique secondaire différent. En conséquence, le système informatique secondaire possède une base de données représentative des informations d'identité suite à la réception des informations converties (330), la base de données étant représentative d'une base de données primaire d'informations d'identité stockées dans le système informatique primaire. Afin d'effectuer une synchronisation, une conversion peut avoir lieu. Le processus de conversion peut être réalisé selon un processus spécial au système secondaire. En variante, la conversion est effectuée par un processus généralisé utilisant des tables de correspondance conçues pour convertir des informations d'identité en plusieurs formats différents.
Patent CA-2502372-A1 (CA)
Inventor: PETERS DAVID J
IPC: H02P6/00
Filed: 2005-03-24
Abstract: A synchronous motor system in which recovery due to a failed field excitation supply is achieved automatically without resort to, or by minimizing the length of time in asynchronous operation of the motor. A sensing system is deployed to provide a sensed signal that is caused by a failed field excitation supply to vary from a reference value by a predetermined amount. A control unit responds to detected failure by automatically changing a field winding system of the motor over from the failed field excitation supply to a standby field excitation supply. The standby supply can be shared by several synchronous motors.
Patent CA-2508115-A1 (CA)
Inventor: CHEN AN MEI
IPC: H04L12/56
Filed: 2003-11-25
Abstract: L'invention se rapporte à un procédé et à un appareil permettant d'envoyer des informations vers une station mobile cible et consistant à déterminer si les informations doivent être envoyées sous forme de messages en courtes rafales de données lorsque ladite station mobile cible est en mode sommeil, et à envoyer des informations vers la station mobile cible sous forme de messages en courtes rafales de données, sans attendre que le canal de trafic soit rétabli.