baber/WOPTO huggingface dataset:
Patent CA-2356891-A1 (CA)
Title: Procedes de discrimination robuste de profils
Inventor: FRIEND STEPHEN H
IPC: C12Q1/68
Filed: 1999-12-21
Abstract: La présente invention concerne des procédés de discrimination entre les effets subtiles d'une première perturbation et d'une seconde perturbation sur un échantillon biologique. En outre, l'invention se rapporte à des procédés destinés à identifier des états maladifs chez des patients, ainsi que des procédés d'optimisation de régimes de thérapie médicamenteuse chez des malades. Enfin, l'invention concerne des procédés améliorés destinés à déterminer les effets discrets d'agents pharmacologiques sur un système biologique.
Patent CA-2358724-A1 (CA)
Inventor: PEGLION JEAN-LOUIS
IPC: C07D211/22
Filed: 2001-10-11
Abstract: -32-   L'invention concerne de nouveaux composés répondant à la formule (I):    dans laquelle X représente un hétérocycle lié au reste de la molécule par un  atome d'azote appartenant audit hétérocycle, ou un groupement -NR 2 R3 dans lequel R2 représente un atome d'hydrogène ou un groupement alkyle, et R3 représente un groupement aryle, 1,3 dihydro-2H-benzimidazolyl-2-one ou alkyle substitué par un hétérocycle; n représente zéro ou 1; R1 représente un atome d'hydrogène ou un groupement alkyle; Ra représente une liaison simple ou une chaîne alkylène; A représente un atome d'azote ou un groupement CH; E représente un atome d'azote ou un groupement CRe dans lequel Re représente soit un atome d'hydrogène, soit une liaison avec un atome de carbone de W, étant entendu que l'un au moins des groupes A ou E représente un atome d'azote; Rb représente une liaison simple ou une chaîne alkylène en C1-C6; W représente un groupement aryle ou hétéroaryle. L'invention vise également les isomères optiques des composés de formule (I)  ainsi que leurs sels d'addition à un acide pharmaceutiquement acceptable. Les composés  selon l'invention sont utiles à titre de médicaments pour le traitement des maladi es ou des conditions pathologiques dans lesquelles une dysfonction endothéliale est connue.
Patent CA-2358915-A1 (CA)
Title: Modified hiv env polypeptides
Inventor: MARTIN ERIC
IPC: A61K48/00
Filed: 1999-12-30
Abstract: Polynucleotide encoding modified HIV Env polypeptides are disclosed. The Env polypeptides are modified so as to expose at least part of the CD4 binding region. Methods of diagnosis, treatment and prevention using the polynucleotides and polypeptides are also provided.
Patent CA-2359220-A1 (CA)
Title: Spike for motor vehicle tires
Inventor: OSTROVSKIS ALLAN
IPC: B29D30/66
Filed: 2001-10-16
Abstract: The invention pertains to a spike for the running surface of a motor vehicle tire, especially a snow tire, with, as seen from above, an out-of-round, elongated, platelike spike root (2, 2a), the greatest extension of which defines a longitudinal axis (7a), and an out-of-round, elongated upper part (4, 5) of the spike, the greatest extension of which defines a longitudinal axis (6a). In order to be enabled to accept even greater forces from below, it is proposed that the spike root (2, 2a) and the upper part (4, 5) of the spike be twisted in relation to each other, so that the longitudinal axis (6a) of the upper part (4, 5) of the spike encloses an angle (15, 15a) varying from zero with the longitudinal axis (7a) of the spike root (2,2a).
Patent CA-2359373-A1 (CA)
Title: Pedicle screw assembly
Inventor: MARTIN GREG
IPC: G06F17/21
Filed: 2001-10-19
Abstract: A stabilizing assembly includes a fastener. The head of the fastener includes a center, a first radial surface and a second radial surface. The first radial surface defines a first radius from the center. The second radial surface defines a second radius from the center. The first radius is greater than the second radius. The assembly includes a coupling element having a rod receiving opening for receiving a stabilizing rod, a bore for receiving the fastener, and a conical-shaped seat for engaging the first radial surface when the fastener is positioned in the bore. A locking element applies a force upon the stabilizing rod. The rod in turn, engages the second radial surface for forcing the underside of the head against the conical-shaped seat so as to prevent further pivotal and rotational movement of the fastener and the coupling element relative to one another.
Patent CA-2359709-A1 (CA)
Title: Formulation de bisoprolol multiparticulaire
Inventor: FANNING NIALL
IPC: A61P5/14
Filed: 2000-01-17
Abstract: Cette invention a trait à une formulation de bisoprolol multiparticulaire à administrer oralement une fois par jour. Chaque particule de cette formulation comporte un noyau bisoprolol ou un sel de celui-ci acceptable du point de vue pharmaceutique recouvert d'un enrobage polymère, lequel enrobage permettant un décalage initial de la libération du bisoprolol in vivo d'au moins 4 à 6 heures après administration et permettant de conserver à l'organisme, par la suite, des concentrations thérapeutiques de bisoprolol pendant les vingt-quatre heures qui suivent. Il est possible d'utiliser cette formulation pour un dosage nocturne de manière à éviter une éventuelle survenue de manifestations cardio-vasculaires aiguës durant la période matinale à haut risque bien connu.
Patent CA-2361795-A1 (CA)
Title: Pre-cut fibrous insulation for custom fitting building cavities of different widths
Inventor: WEINSTEIN LARRY J
IPC: E04B1/78
Filed: 2001-11-09
Abstract: A fibrous insulation blanket is pre-cut for custom fitting the insulation blanket into wall, floor, ceiling and roof cavities of different widths formed by the framework of a building. The insulation blanket has one or more pairs of longitudinally extending cuts in the major surfaces of the blanket. Each pair of cut(s) leaves a separable connector within the blanket between adjacent sections of the insulation blanket whereby the blanket can be handled as a unit for insulating a cavity having a width about equal to the width of the blanket or easily separated or torn apart by hand at a separable connector for insulating a cavity having a lesser width. A major surface of the blanket may have a facing bonded thereto that is separable by hand along the cut(s) in the major surface to facilitate separating the blanket by hand. Preferably, the facing has tabs for securing the insulation blanket to framing members and when one or more perforated lines are used in the facing, the perforations of the perforated line(s) in the facing are closed by the bonding agent bonding the facing to the blanket so that the facing functions as a vapor barrier in spite of the perforations.
Patent CA-2364537-A1 (CA)
Inventor: RUSSELL BRANCH J
IPC: C10L1/18
Filed: 2000-03-30
Abstract: A fuel cell fuel, a method of making a fuel cell fuel, a fuel cell system utilizing Fischer-Tropsch feed and a method of operating a fuel cell are disclosed. The fuel cell fuel is a light Fischer-Tropsch liquid having at least 77 wt.% normal and iso-paraffins, les than 20 wt.% olefins, less than 9 wt.% alcohols, less than 0.001 wt.% sulfur and less than 5 wt.% aromatics. T he process of making the fuel cell fuel includes separating a heavy portion fro m a Fischer-Tropsch liquid, hydrocracking the heavy portion and separating a C 5- C18 portion from the hydrocrackate.
Patent CA-2364654-A1 (CA)
Inventor: MORI HIROSHI
IPC: C08K5/3415
Filed: 2000-04-05
Abstract: Incorporation of an odor-reducing additive selected from the group consisting of: (i) a low molecular weight primary or secondary amino compound of low volatility, containing at least one amino group and two or more carbon atoms and having a weak basicity of Pkb in the range of 2 - 8; (ii) succinimide;  (iii) anthranilic acid; (iv) 4-amino benzonic acid, and mixtures thereof, into a polyacetal resin to reduce its formaldehyde odor. A combination of the odor-reducing additive with a weak acidic imino was found to have a synergistic effect in further reducing the formaldehyde odor.
Patent CA-2364674-A1 (CA)
Inventor: DETER CHRISTHARD
IPC: G02B26/12
Filed: 2000-11-22
Abstract: La présente invention concerne un projecteur permettant de simuler une image de scène, notamment la vue à partir d'un avion, au moyen de lumières calligraphiques. Selon ce procédé, un système de commande, connecté à un modulateur du projecteur, produit des signaux pour l'image de scène et des signaux pour les lumières calligraphiques. Cette invention est caractérisée en ce que le projecteur (100) comprend deux sources lumineuses (10, 10'). Chacune de ces sources lumineuses produit un faisceau lumineux R-G-B ( PHI A(t)) et ( PHI B(t)), colinéaire, à modulation de couleur et de luminosité, respectivement dans un rapport temporel défini par rapport à l'autre source lumineuse et au moyen des signaux (A, B) issus du système de commande (60). Des modulateurs (2) sont commandés dans la première source lumineuse (10) au moyen d'un premier signal (A), de façon qu'un premier faisceau lumineux R-G-B ( PHI A(t)) contient l'information optique pour l'image de scène (17) et l'information optique pour les lumières calligraphiques, et des modulateurs (2') sont commandés dans la seconde source lumineuse (10') au moyen d'un second signal (B), de façon qu'un second faisceau lumineux R-G-B ( PHI B(t)) ne contient que l'information optique pour les lumières calligraphiques. Un système permettant de combiner les faisceaux (20) est également pourvu. Le premier et le second faisceaux lumineux R-G-B ( PHI A(t)) et ( PHI B(t)) rayonnent à partir de ce système, de manière spatialement combinée, et sont simultanément projetés sur la surface de projection au moyen d'un système de déviation unique à deux axes (11, 12; 18), de façon que les deux faisceaux lumineux R-G-B ( PHI A(t)) et ( PHI B(t)) se superposent, en fonction de la luminosité, dans les points de l'image dans lesquels les lumières calligraphiques sont représentées.
Patent CA-2365293-A1 (CA)
Title: Compositions and methods for recombinant adeno-associated virus production
Inventor: NONY PASCALE
IPC: C12N7/01
Filed: 2000-03-03
Abstract: The present invention relates to methods and compositions for the production of recombinant Adeno-Associated Viruses (rAAV). In particular, the invention discloses nucleic acid constructs and packaging cells having improved properties for rAAV production, as well as methods of titration and characterization of rAAV preparations. The invention also describes sequences which promote or increase the packaging of nucleic acids in rAAV, and their use for producing rAAV with high efficiency. The invention can be used for producing or testing high quality rAAV preparations, for biological, preclinical, clinical or pharmaceutical uses.
Patent CA-2365378-A1 (CA)
Inventor: RAYMOND RONALD P
IPC: F16L17/067
Filed: 2001-12-18
Abstract: A sealing member having an elongate body formed of an elastomeric material has a generally planar sealing surface adapted to provide an outward sealing force in a direction generally perpendicular to the sealing surface.  The seal further includes a plurality of longitudinally extending hollow regions formed within the sealing member which are bounded at least in part by longitudinally extending and transversely spaced apart structural partitions. A layer of elastomeric material on a side opposite the sealing surface spans the structural partitions thus enclosing the hollow regions. The seals are useful in constructing segmented tunnels, ducts, and the like, and are particularly adapted to withstand high pressures.
Patent CA-2367293-A1 (CA)
Title: Implement suspension with accumulator
Inventor: HOOK RICHARD WAYNE
IPC: A01B63/14
Filed: 2002-01-08
Abstract: An implement frame supported by hydraulically controlled lift wheels includes accumulator structure which is selectively connectable by valve structure to the lift cylinder circuit to control flow between the cylinder and accumulator according to implement status. For transport, the valve structure is opened for absorption of shock loads as the lift wheels move over obstructions and surface irregularities. For working in the field, the valve structure is closed to provide stable lift and precise depth control functions. The valve structure can be operated manually or automatically in response to vertical frame movement. In one embodiment, proportional valves are connected to an implement control unit for active suspension control which varies with changing transport conditions. A similar accumulator structure is provided for the hitch weight transfer system.
Patent CA-2369122-A1 (CA)
Title: Building construction bid and contract management system, internet-based method and computer program therefor
Inventor: CROOKSHANKS REX J
IPC: G06Q30/06
Filed: 2000-06-05
Abstract: The present invention relates to a system and method ("Bid System") for topologically subdividing and defining the detail scope of work and for inter-linking construction plans and specifications to construction contracts and subcontracts. The Bid System permits full, clear and unambiguous definition of the scope of work under each subcontract, so as to eliminate errors and uncertainty relating to contract performance. The Bid System establishes a series of electronic overlays to the digitized construction plans corresponding to different trades or categories of work, in which each overlay may be divided into a series of optimized topological subdivisions or "boxes" which uniquely identify and locate on the plans a portion of the work to be performed. The system includes linkage of the overlays and boxes to the subcontracts whereby the scope of work to be bid is accurately associated or "mapped" to corresponding regions and overlay category on the architectural drawings or construction plans. This mapping of overlays to plans constitutes a system of almost-orthogonal equations having the property of progressively increasing transparency as the typical size of the subdivisions is reduced. The system and method also permits a bi-directional flow of information from the various entities involved in the bid process so as to enhance the clarity and detail of work description of both the contracts and the plans and specifications, thus permitting more efficient and effective monitoring and management of contract performance.     Internet-based embodiments of the Bid System of the invention are described, including a central-server remote host Internet embodiment in which the transmittal of data, including plans, overlays, contracts, bids, comments, edits, changes and the like are via the Internet, the Bid System being operated principally on a central remote host operated by a Bid System Service Provider (BSSP). Distributed host Internet embodiments are also disclosed.
Patent CA-2369644-A1 (CA)
Title: Modular kiosk
Inventor: BOWRON JULIAN
IPC: G07F9/10
Filed: 2002-01-28
Abstract: An automated kiosk has (a) a cabinet; (b) a face frame releasably securable to the cabinet; (c) a plurality of cross members secured to the face frame; and (d) a plurality of hardware components releasably secured to the cross members. The hardware components may be sized and configured such that they project substantially directly inward into the cabinet when the face frame is secured to the cabinet. A method of modifying a kiosk of the invention, comprises (a) removing a hardware component or a faceplate from the kiosk; (b) repositioning a cross member on the kiosk; and (c) installing a new hardware component on the kiosk. A method of constructing a kiosk of the invention comprises (a) assembling a cabinet to a face frame; (b) receiving an order which designates the hardware components required for the kiosk; (c) securing a plurality of cross members to the face frame in a configuration suitable for receiving the designated hardware components; and (d) securing the designated hardware components to the cross members.
Patent CA-2371708-A1 (CA)
Inventor: WOOD KENNETH R
IPC: H01Q15/12
Filed: 2000-05-23
Abstract: A compact lightweight antenna for receiving microwave direct line of sight wireless data signals used in services such as Local Multipoint Distribution Services (LMDS). The antenna provides for precise control over isolation of polarized signals. The antenna consists of an external parabolically shaped dome formed of a suitably resilient material such as thermoplastic. A  polarizing metal grid is formed on the interior surface of the dome and serves as a transreflector for initially passing received radiation having a vertical polarization. A twist reflector disposed at a point along an axis defined by the metal grid reflects the received radiation, back in the direction of the transreflector with a different polarization. The now differently polarized energy is reflected by the parabolically shaped metal grid at a feed point located in the center of the twist plate. Operation for transmitting energy is analogous.
Patent CA-2375862-A1 (CA)
Inventor: EBRAHIMI TOURADJ
IPC: G06T7/20
Filed: 2000-06-07
Abstract: An algorithm for video summarization is described. The algorithm combines photometric and motion information. According to the algorithm the correspondence between feeature points is used to detect shot boundaries and to select key frames. Thus, the rate of feature points, which are lost or initiated, is used as an indication if a shot transition occurred or not. Key frames are selected as frames where the activity change is low.
Patent CA-2376277-A1 (CA)
Title: A method of developing an interactive system
Inventor: STARKIE BRADFORD CRAIG
IPC: H04M3/493
Filed: 2000-06-09
Abstract: A method of developing an interactive system, including inputting application data representative of an application for the system, the application data including operations and parameters for the application, generating prompts on the basis of the application data, and generating grammar on the basis of the application data. The prompts and grammar are generated on the basis of a predetermined pattern or structure for the prompts and grammar. The grammar also includes predefined grammar.  Grammatical inference is also executed to enhance the grammar. The grammatical inference method for developing the grammar may include processing rules of the grammar, creating additional rules representative of repeated phrases, and merging equivalent symbols of the grammar, wherein the rules define slots to represent data on which an interactive system executes operations and include symbols representing at least a phrase or term. The grammar is hierarchical and the rules include a reference count representing the number of other rules that reference the rule. Additional rules to be created during grammatical inference are determined on the basis of attribute constraints.
Patent CA-2376806-A1 (CA)
Inventor: WETZEL RODNEY J
IPC: E21B21/00
Filed: 2002-03-14
Abstract: A tool string for use in a well to retrieve a completion string while maintaining control of a well without having to kill the well (i.e., without having to exceed formation pressure) each time the string is retrieved.
Patent CA-2377425-A1 (CA)
Inventor: LENOIR OLIVIER
IPC: H04L29/06
Filed: 2000-06-16
Abstract: The invention concerns a method for making secure the access to a computer server from a client site via at least a first communication network, said server comprising means for managing a protocol authenticating a user of a client site, comprising a reception sequence and processing of identification data of a user of a client site, and a sequence for transmitting a message from the server site to a communication equipment held by the user of the client site via a second communication network. The transmitted message is a voice message to be processed directly by said user to generate an authenticating password designed to be transmitted to said server site via one or the other of the first or second communication networks. The invention provides the advantage of enhancing security of authenticating protocols, particularly existing ones, at lower costs.
Patent CA-2378473-A1 (CA)
Title: Modulation of platelet activation
Inventor: KAHN MARK
IPC: A61K38/08
Filed: 1999-08-24
Abstract: Methods of modulating thrombin-mediated platelet activation by inhibition or  enhancement of protease-activated receptor 4(PAR4) and protease-activated receptor 1(PAR1) activity are disclosed. This method provides a way of substantially blocking all thrombin-mediated activation of platelets by 1) inhibiting signalling though PAR1 and 2) inhibiting signalling through PAR4.  Signalling through each PAR receptor may be inhibited at various molecular levels, including: the level of ligand binding (e.g.by administration of an antagonist), the level of the receptor activity (e.g. blocking expression of the receptor in the relevant cells) and/or intracellularly, (e.g.blocking expression or activity of a molecule required for activity of the receptor). Alternatively, this method provides a method for enhancing thrombin-mediated platelet activation by specifically activating PAR1 and PAR4. These methods may take place in vivo, through administration of the appropriate compounds, or in vitro, e.g.the ex vivotreatment of a sample.
Patent CA-2378784-A1 (CA)
Inventor: BASTIAN JOHN M
IPC: B08B15/02
Filed: 2002-03-25
Abstract: A fume hood includes a top, bottom sidewalk, front panel and a back panel that define an enclosed workspace. The fume hood also includes a movable sash for opening and closing an access opening and an airfoil disposed proximate an edge portion of the opening to direct airflow through the opening and into the workspace. The airfoil is automatically raised from a down position to an up position when the sash is raised to a predetermined height. In addition, the airfoil may be automatically raised when the velocity of the airflow into the access opening decreases below a predetermined value. Once raised, the airfoil may be automatically or manually lowered to the down position. In one embodiment, the airfoil includes one or more fins having an angled portion that extends downwardly below the work surface of the fume hood when the airfoil is in the down position, thereby reducing the possibility of a potential spill when the technician removes an item from the workspace.
Patent CA-2379276-A1 (CA)
Title: Method and apparatus for sealing capsules and capsules suitable for use in said method and apparatus
Inventor: PETITJEAN FRANCOIS
IPC: A61J3/07
Filed: 2000-06-30
Abstract: The invention is concerned with a method of sealing a hardshell capsule having coaxial body parts which overlap when telescopically joined with each other, thereby forming a gap around a circumference of the capsule, comprising the steps of individually applying a sealing liquid including a solvent uniformly to the external edge of the gap of a capsule to be sealed to form a liquid ring around the circumference of the capsule, removing excess sealing liquid from the exterior of the capsule, drying the capsule by applying thermal energy from outside while gently tumbling and conveying the capsule on a spiral path.
Patent CA-2382011-A1 (CA)
Title: Collection and disposal device
Inventor: BOULTON DAVID
IPC: A01M5/08
Filed: 2000-08-18
Abstract: A device is provided for the collection and disposal of insects and similarly sized detrital objects. The device includes an air inlet end through which air can be entrained, and an air outlet from which said entrained air is expelled.  The device also includes a hollow duct portion through which entrained air passes and a filter means provided between the inlet and the outlet which prevent insects from being expelled through the outlet. Means are provided to create a pressure differential between the air inlet and air outlet of the device, such that air is entrained in the inlet and drawn through the duct portion of the device towards the outlet, additionally passing through the filter. The pressure differential is sufficient to entrain air, insects and/or detritus into the duct portion and the air path defined through the device is substantially unhindered so that entrained insects and detritus can escape from the device along the same path by which they were entrained ultimately exiting from the inlet end of the duct when the pressure differential is reduced, eliminated or reserved.