baber/WOPTO huggingface dataset:
Patent CA-3185501-A1 (CA)
Title: Process for recovering close boiling products
Inventor: GAO ALLAN HAIMING
IPC: C12P7/06
Filed: 2019-12-20
Abstract: The disclosure is directed to a method for recovering products from a fermentation broth. The disclosure relates to the use of extractive distillation and/or dehydration to recover products which have close boiling points, such as ethanol and isopropanol, from a fermentation broth.  In an embodiment, the recovery of product is completed in a manner that minimizes stress on the microbial biomass, such that it remains viable, at least in part, and may be recycled and reused in the fermentation process, which may result in increased efficiency in the fermentation process. The extractive distillation vessel and/or dehydration reactor may be used downstream of a distillation vessel. To minimize stress on the microbial biomass the distillation vessel may be under vacuum. The extractive distillation vessel may be used alongside a separation vessel such that the separation vessel is capable of recycling extractive distillation agent.
Patent CA-3185579-A1 (CA)
Inventor: NAKASHIMA KENTARO
IPC: A61K31/167
Filed: 2022-12-20
Abstract: Disclosed is a patch comprising an adhesive layer on a backing layer, wherein the adhesive layer comprises lidocaine or a phalmaceutically acceptable salt thereof, propylene glycol, a rubber adhesive base and a terpene resin, wherein the content of the lidocaine or a pharmaceutically acceptable salt thereof in the adhesive layer in terms of free form is 2 mass% to 6 mass% with respect to the total mass of the adhesive layer, wherein the ratio of the mass of the lidocaine or a pharmaceutically acceptable salt thereof in terms of free folha to the mass of propylene glycol in the adhesive layer is 1:0.6 to 1:1.8, and wherein the content of the terpene resin in the adhesive layer is 5 mass% to 18 mass% with respect to a total mass of the adhesive layer.
Patent CA-3186824-A1 (CA)
Inventor: MUNROE MELISSA
IPC: C12Q1/6883
Filed: 2021-07-21
Abstract: A method for determining whether a Systemic lupus erythematosus (SLE) patient is undergoing a pre-flare event, the method comprising obtaining a blood, serum, plasma, or saliva sample from the SLE patient; assessing a level of expression for each of a plurality of biomarkers, the plurality of biomarkers comprising OPN, MCP-1/CCL2, MCP-3/CCL7, IL-17A, TNFRII, TNFRI, IL-4, IL-5, BLyS, TNF?, and IL-7; determining a Lupus Flare Risk Prediction Index (LFPI) for the patient based upon the level of expression for each of a plurality of biomarkers; and based upon the LFPI, determining whether the patient is undergoing a pre-flare event.
Patent CA-3188169-A1 (CA)
Inventor: VAN DER WEIJDE JOHANNES OOSTEN
IPC: B60L53/37
Filed: 2021-06-30
Abstract: La présente invention concerne un dispositif de positionnement d'un connecteur de chargeur, en particulier par rapport à un contre-connecteur de véhicule, comprenant une suspension pour un ensemble câble de charge, relié à une extrémité au connecteur de chargeur, la suspension comprenant un premier point de suspension, de serrage, en un point éloigné de ladite extrémité, l'ensemble câble de charge dans une orientation et une position préétablies, lesquelles orientation et position conjointement à la rigidité de l'ensemble câble et la gravité agissant sur l'ensemble câble délimitent une position préférée et/ou une orientation préférée de ladite extrémité ; et un second point de suspension, pour venir en prise avec l'ensemble câble de charge à l'extrémité du connecteur de chargeur ; le second point de suspension comprenant un manipulateur pour manipuler la position et/ou l'orientation du connecteur de chargeur par rapport au monde fixe, dans une plage autour de la position préférée et/ou de l'orientation préférée de l'extrémité de l'ensemble câble.
Patent CA-3188949-A1 (CA)
Title: Methods and compositions comprising anti-scalants
Inventor: GRIFFIN RICK
IPC: C02F5/10
Filed: 2021-08-13
Abstract: The present disclosure generally relates to methods and compositions for the treatment of scale, such as controlling, preventing, and/or inhibiting scale formation and/or the rate of scale formation, in a fluid in need of treatment, such as fluids used in and/or resulting from oil and gas operations, wherein said treatment comprises the use of one or more anti-scalants. The one or more anti-scalants may comprise desirable biodegradation characteristics as well as enhanced divalent ion tolerance, such as calcium ion tolerance.
Patent CA-3189244-A1 (CA)
Title: Texaphyrin derivatives for manganese chemotherapy, photoacoustic imaging, and photothermal therapy
Inventor: SESSLER JONATHAN L
IPC: A61K49/00
Filed: 2021-08-14
Abstract: The present disclosure relates to manganese containing texaphyrin compounds of the formula (I). Wherein the variables are as described herein. The present disclosure also provides pharmaceutical compositions of the compounds. Also, provided herein are methods of using the compounds in the treatment of cancer including platinum resistant cancer.
Patent CA-3190747-A1 (CA)
Title: Methods and uses of producing compositions stably comprising free available chlorine species and peroxides
Inventor: ALIMI HOJABR
IPC: A01N31/02
Filed: 2021-08-25
Abstract: The present specification discloses a method of making a composition stably comprising one or more peroxides and one or more free available chlorine species, one or more peroxide for use in the manufacture of a composition stably comprising one or more peroxides and one or more free available chlorine species, as well as formulated compositions using a composition manufactured according to a method or use disclosed herein.
Patent CA-3190995-A1 (CA)
Inventor: CUCINELLI NICHOLAS S
IPC: A61B5/1455
Filed: 2021-08-09
Abstract: A method and apparatus for non-invasively diagnosing a condition of subcutaneous biological tissue using biomolecular Raman spectroscopy. The apparatus is immobilized against the skin of a user so that a light source can emit photons of light through a bottom port that probes physiological biomarkers in molecules of interest in subcutaneous tissue. Photons of Rayleigh scattered light commingled with Raman scattered light are returned into the internal cavity through the port. After having been filtered of Rayleigh scattered light and limited to a specific wavelength, the photons are detected in an array of photodetectors where photons of Raman scattered light are singly counted over a predetermined sampling time. The apparatus and method can be configured in wearable form, for example a wristband, to monitor a variety of conditions, including reading blood sugar.
Patent CA-3193459-A1 (CA)
Inventor: OTSCHIK JOACHIM
IPC: F16J15/34
Filed: 2021-08-24
Abstract: The invention relates to a method for operating a mechanical face seal assembly (1) comprising a mechanical face seal (2) with a rotating seal ring (3) and a stationary seal ring (4) which define a seal gap (5) between their seal faces, said method comprising the steps of: detecting operating data and/or ambient data of the mechanical face seal assembly (2); transmitting the operating data and/or ambient data detected to a digital twin (31) of the mechanical face seal assembly (2); simulating and monitoring the operation of the mechanical face seal assembly (2) by means of the digital twin (31) on the basis of the operating data and/or ambient data of the mechanical face seal (2) transmitted ; and transmitting back a simulation result and/or data of the digital twin.
Patent CA-3193811-A1 (CA)
Inventor: SAH DINAH WEN-YEE
IPC: A61P25/28
Filed: 2015-11-13
Abstract: The present invention relates to small interfering RNA (siRNA) molecules against the SOD1 gene, adeno-associated viral (AAV) vectors encoding siRNA molecules and methods for treating amyotrophic lateral sclerosis (ALS) using the siRNA molecules and AAV vectors.
Patent CA-3194513-A1 (CA)
Inventor: SCHWARZ SEBASTIAN
IPC: H02K1/18
Filed: 2023-03-29
Abstract: The invention relates to a planar drive system (10) comprising at least two stator modules (12) and a frame (14), wherein each of the stator modules (12) has a base body (16) with a transport surface (18) and a rear side (20) opposite the transport surface (18), and further a mounting plate (22) which is detachably mounted on the rear side (20) of the base body (16), wherein the frame (14) comprises a plurality of receptacles (24) for receiving a stator module (12), wherein the stator modules (12) is insertable into the receptacles (24) of the frame (14) with the transport surface (18) forward and is lockable in the receptacle (24) by means of a locking mechanism (26). The invention also relates to a method for the installation and removal of stator modules (12) in a planar drive system (10). <MG>
Patent CA-3195026-A1 (CA)
Title: Distributed braking architecture with improved safety
Inventor: FREY OLIVIER
IPC: B60T13/74
Filed: 2021-10-06
Abstract: The invention relates to an architecture of a braking system for aircraft (1000), comprising a brake (20); an electromechanical actuator (30) associated with a power module (33) connected to a digital communication module (34) by a first control module (35); a controller (50) comprising a power supply unit (51) intended to supply the power module (33) with a supply voltage (Vc) and a control unit (52) connected to a digital communication unit in order to transmit a digital command signal to the digital communication module (34). The control unit (52) is also connected to the control module (35) by an analogue wire link (60) so as to transmit to same a first analogue braking command from which the first control module (33) controls the power module (33) in order to produce a degraded supply current of the actuator.
Patent CA-3195543-A1 (CA)
Inventor: GELBAUM DANA
IPC: A61K31/506
Filed: 2021-09-17
Abstract: La présente invention concerne des méthodes de traitement ou de suppression d'un carcinome adénoïde kystique (CAK) ou d'inhibition de la croissance tumorale d'un CAK chez des sujets par l'administration de compositions comprenant des composés de bisfluoroalkyl-1,4-benzodiazépinone, comportant des composés de formule (III) ou des promédicaments correspondants.
Patent CA-3197673-A1 (CA)
Title: System and method for machine learning based malware detection
Inventor: GRAVES LAURA MICAH
IPC: G06N20/00
Filed: 2023-04-21
Abstract: A method comprises obtaining a training set of network data that includes benign network data and malware network data; engaging a feature extraction engine to generate a set of dyads for each source-destination pair in the training set of network data; and training, using the set of dyads, a machine learning engine to differentiate between the benign network data and the inalware network data.
Patent CA-3197763-A1 (CA)
Title: Compositions et methodes pour ameliorer la penetration de lymphocytes t de tumeurs et de cancers
Inventor: CATO ALLEN
IPC: A61K39/39
Filed: 2021-11-08
Abstract: L'invention concerne des méthodes pour améliorer des immunothérapies antitumorales et/ou anticancéreuses. Selon certains modes de réalisation, les méthodes comprennent l'administration à un sujet qui en a besoin d'une composition qui comprend un conjugué qui comprend un immunogène de gastrine conjugué à un support immunogène, éventuellement conjugué par l'intermédiaire d'un lieur, en une quantité et par l'intermédiaire d'une voie suffisantes pour améliorer l'entrée dans la tumeur et/ou le cancer d'un lymphocyte T anti-tumoral, une immunothérapie antitumorale et/ou anticancéreuse étant ainsi améliorée. L'invention concerne également des compositions pharmaceutiques qui comportent les conjugués destinés à être utilisés dans le traitement de tumeurs et de cancers, des méthodes pour traiter des tumeurs et/ou des cancers, et des méthodes pour sensibiliser des tumeurs et/ou cancers solides chez des sujets à des thérapies par lymphocytes T récepteurs d'antigènes chimériques (CAR -T).
Patent CA-3198766-A1 (CA)
Title: Systemes et procedes permettant la creation d'un lenticule pour une presbytie
Inventor: BOR ZSOLT
IPC: A61F9/008
Filed: 2021-12-09
Abstract: Dans certains modes de réalisation, un système chirurgical ophtalmique permettant la création d'un lenticule dans la cornée d'un ?il comprend des composants pouvant être commandés (comprenant une source laser et un scanner) et un ordinateur. La source laser génère un faisceau laser, et le scanner dirige le point focal du faisceau laser. L'ordinateur détermine une forme de lenticule pour le lenticule ayant un côté postérieur et un côté antérieur. Le côté postérieur ou le côté antérieur a une partie centrale et une partie périphérique. La forme de lenticule est façonnée à l'aide d'une petite lentille majeure et d'une petite lentille mineure, la petite lentille majeure étant conçue pour corriger l'emmétropie. La forme de lenticule est façonnée par soustraction de la petite lentille mineure à la petite lentille majeure, la soustraction de la petite lentille mineure produisant la partie centrale. L'ordinateur ordonne à un ou plusieurs des composants pouvant être commandés de créer le lenticule.
Patent CA-3201993-A1 (CA)
Inventor: CHEN SHAOLIANG
IPC: A61B18/12
Filed: 2015-07-10
Abstract: A multi-pole synchronous pulmonary artery radiofrequency ablation catheter, wherein an adjustment apparatus is arranged on a control handle; a catheter body is hollow, and a cavity is arranged therein; a lead wire, a temperature sensing wire and a pull wire are arranged in the cavity; one end of the catheter body is flexible, and the flexible end is connected to an annular ring; the other end of the catheter body is connected to the control handle; one end of the pull wire is connected to the flexible end, and the other end of the pull wire is connected to the adjustment apparatus on the control handle, the tension of the pull wire is adjusted through the adjustment apparatus to achieve radian control of the flexible end; a shape memory wire is arranged in the annular ring, one end of the shape memory wire extends to the end of the annular ring and the other end of the shape memory wire passes through the root of the annular ring and is fixed on the flexible end of the catheter body; the annular ring is provided with an electrode group with each electrode connected to the lead wire and temperature sensing wire; the lead wire and temperature sensing wire go through the catheter body and are electrically connected to the control handle. The device uses cold saline perfusion method to protect the vascular intima and possesses advantages of simple operation, short operation time and controllable precise ablation. The device can be used to treat pulmonary hypertension with pulmonary denervation.
Patent CA-3203537-A1 (CA)
Title: Composition pharmaceutique composite pour le traitement d'une maladie du cerveau, comprenant un inhibiteur de cholinesterase et un antioxydant
Inventor: LEE JI HYUN
IPC: A23L33/10
Filed: 2021-10-28
Abstract: La présente invention concerne une composition pharmaceutique composite destinée au traitement d'une maladie du cerveau, comprenant un inhibiteur de cholinestérase et un antioxydant, et plus précisément une composition destinée à la prévention ou au traitement d'une maladie du cerveau, comprenant : un inhibiteur de cholinestérase présentant un effet synergique sur la protection neuronale et le développement de la différenciation neuronale ; et un antioxydant.
Patent CA-3204440-A1 (CA)
Inventor: STRANDBERG MICHAEL
IPC: B66C23/28
Filed: 2022-01-26
Abstract: A connecting device for securing beams end to end has a pin, a shaft and at least one splice element having a first hole for receiving the shaft and a second hole spaced apart from the first hole for receiving the pin. A gap is between the pin and the splice element when the pin is inserted in the second hole. The shaft is rotatable relative to the splice element when the shaft is in the first hole. An eccentric ring in the first hole is rotatable relative to the first hole and has an opening for receiving the shaft, the ring rotatable upon rotation of the shaft in the opening. The centre of the ring is offset from a rotational axis of the shaft so that the splice element moves relative to the pin upon rotation of the shaft thereby closing the gap on one side of the pin.
Patent CA-3205314-A1 (CA)
Inventor: VALENTE PEDRO
IPC: F26B3/06
Filed: 2022-01-18
Abstract: La présente invention concerne un procédé de séchage de la teneur en solvant résiduel d'un produit ou poudre pharmaceutique. La présente invention concerne un procédé qui permet le séchage rapide de poudres pharmaceutiques fines et cohésives permettant son utilisation pour une opération discontinue, semi-continue et continue.
Patent CA-3210626-A1 (CA)
Inventor: SAYRE RICHARD
IPC: A61K9/127
Filed: 2022-02-02
Abstract: The present invention is directed to Saccharomyces-generated extracellular vesicles (EVs) comprising a foreign RNA molecule or protein and at least one foreign membrane surface exposed ligand that specifically binds to a target receptor displayed on a target cell. The present invention also relates to methods of making and using these Saccharomyces-generated EVs for targeted gene silencing. The present invention also relates to fusion proteins comprising a Saccharomyces extracellular vesicle anchor protein and a second peptide designed to bind to cell-specific receptors.
Patent CA-3210959-A1 (CA)
Inventor: DE GAILLANDE CHRISTOPHE
IPC: B65H7/08
Filed: 2022-02-28
Abstract: A positioning assembly (30) for positioning a sheet material, especially at an entry portion of a sheet material processing machine, is described. It comprises a support beam (32) on which at least a portion of a sheet material to be positioned can be placed and a plurality of clamping fingers (38). The support beam (32) is 5coupled to a drive unit (60) configured for translationally moving the support beam (32) along a travelling direction (y) of the sheet material, translationally moving the support beam (32) along a direction (x) transverse to the travelling direction (y) and rotationally moving the support beam (32) with respect to a pivot axis (z) being perpendicular to the traveling direction (y) and the transverse direction (x). Each of 10the clamping fingers (38) is coupled to an individual clamping finger actuation unit (40). Moreover, a sheet material processing machine comprising such a positioning assembly (30) is presented.
Patent CA-3214453-A1 (CA)
Inventor: YAMIN LEYLA
IPC: A61M39/22
Filed: 2022-03-29
Abstract: IV filters are described herein. An IV filter includes a filter housing, a filter media, a filter channel, a priming channel, and a disk valve. The filter housing defines an inlet and an outlet. The filter media is disposed within the filter housing. The filter channel is disposed within the filter housing. The filter channel is in fluid communication with the inlet and the filter media, and the filter media permits flow from the filter channel to the outlet and captures particulate from the flow. The priming channel is disposed within the filter housing. The priming channel is in fluid communication with the inlet and the outlet. The disk valve is coupled to the filter housing. The disk valve is moveable to direct flow from the inlet to the priming channel in a first position and to direct flow from the inlet to the filter channel in a second position.
Patent CA-3216373-A1 (CA)
Title: Parp1 inhibitors and uses thereof
Inventor: TRZOSS LYNNIE
IPC: C07D471/04
Filed: 2022-04-19
Abstract: Described herein are PARP1 inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of cancer.
Patent CA-3221938-A1 (CA)
Title: Analogues de tetrahydrofurane substitues utiles en tant que modulateurs de canaux sodiques
Inventor: BECK ELIZABETH MARY
IPC: C07D405/12
Filed: 2022-06-03
Abstract: L'invention concerne des composés de formule I, et des sels pharmaceutiquement acceptables de ceux-ci, utiles en tant qu'inhibiteurs de canaux sodiques. L'invention concerne également des compositions pharmaceutiques comprenant ces composés ou ces sels pharmaceutiquement acceptables et des procédés d'utilisation de ces composés, de ces sels pharmaceutiquement acceptables et de ces compositions pharmaceutiques dans le traitement de divers troubles, notamment de la douleur.
Patent CA-3222109-A1 (CA)
Inventor: PFEIFER PETER
IPC: B01J19/00
Filed: 2022-05-27
Abstract: L'invention concerne un réacteur à structure multicouche, les différentes couches étant structurées de manière particulière, dans des modes de réalisation préférés ayant des évidements carrés, pour permettre le transport de la chaleur d'une manière améliorée pendant les réactions catalytiques. La présente invention concerne également des structures multi-réacteurs, des procédés pour fournir les réacteurs et les structures multi-réacteurs, et leurs utilisations et applications.
Patent CA-3224947-A1 (CA)
Title: Method for preparing an integrated production complex on a gravity-based structure (gbs)
Inventor: Mikhelson Leonid Viktorovich
IPC: B63B73/20
Filed: 2022-07-14
Abstract: The invention relates to the construction of production facilities. In order to prepare a production complex, superstructure modules are prepared on a production platform, which includes the steps of preparing assembly units, abrasively cleaning and painting said assembly units, and assembling the units into modules. The modules are transported to the location of a base and are moved into position on said base, the latter being mounted in a dry dock, whereupon the modules are integrated with one another and with the base. The base is a gravity-based structure that is capable of remaining in a floating state during transportation to an installation site. The result is resistance to the effect of ice in a body of water with an ice regime, easier manoeuvre of individual superstructure modules about the surface of a production platform, and the creation of special bridge structures for transferring superstructures onto a base.
Patent WO-9214015-A1 (WO)
Inventor: LUSTIG WILLIAM H
IPC: E04G13/00
Filed: 1992-02-04
Abstract: L'appareil de moulage visé ici a une forme allongée dans le sens horizontal et présente une grande souplesse. Il est réalisé en diverses longueurs et largeurs, en fonction des besoins de l'utilisateur. Des pattes (11) verticlales sont soudées à l'extérieur de la forme, à des invervalles prédéterminés, pour accueillir une cornière (12) en acier qui assure à la fois la rectitude dans le sens horizontal et la rigidité du moule. En supprimant ladite cornière (12) on obtient toute courbe désirée, concave ou convexe. Un dispositif de calage manuel (10), constitué de deux sections de tube d'acier dont l'une présente un alésage supérieur au diamètre extérieur de l'autre, de sorte que l'une coulisse dans l'autre, permet de caler les formes horizontalement. Soudé à ce dispositif de calage, un tube vertical comportant une vis de calage maintient en position verticale une tige d'acier. Ladite tige d'acier est fichée en terre pour assurer la stabilité, le calage en hauteur étant obtenu au moyen de la vis de calage. Chaque longueur de moule comporte des embouts soudés à l'angle droit, de sorte que deux longueurs peuvent être réunies bout à bout par une enture mâle/femelle. Pouvant être aboutés de la sorte, ces éléments peuvent être assemblés puis séparés pour être acheminés vers un autre chantier.
Patent WO-9529738-A1 (WO)
Title: Dispositif absorbeur d'energie
Inventor: SMALL GREGORY ERIC
IPC: A62B35/04
Filed: 1995-04-27
Abstract: Un dispositif absorbeur d'énergie permet d'arrêter des corps en mouvement de manière sûre. Ses utilisations incluent des systèmes anti-chute qui protègent des chutes accidentelles les ouvriers se trouvant sur des structures élevées. Ce dispositif absorbeur d'énergie comprend une bande enroulée pouvant dissiper de l'énergie quand une force de traction appliquée à ce dispositif produit une contrainte de courbure interne qui dépasse la limite d'élasticité du matériau. La charge de traction appliquée à la zone de sécurité pendant une chute accidentelle déroule cette bande, ce qui permet d'absorber progressivement l'énergie cinétique du corps en mouvement.