baber/WOPTO huggingface dataset:
Patent CA-2224626-C (CA)
Inventor: DE GRAAF LEENDERT HENDRIK
IPC: C12N15/65
Filed: 1996-06-24
Granted: 2011-11-01
Abstract: La présente invention concerne le domaine de la mutation des microorganismes et de la sélection des mutants. L'invention vise en particulier à obtenir des mutants métaboliques d'une manière simple, directe et spécifique. Selon un mode de réalisation préférentiel, il est également possible d'obtenir des mutants désirés qui ne comportent pas d'ADN recombinant, ce qui facilite leur incorporation à des produits destinés à la consommation ou à une application humaines, grâce à des procédures législatives plus brèves. Le procédé de l'invention concerne la mutation aléatoire et la sélection spécifique du mutant métabolique désiré. Une cassette d'acide nucléique comprend une séquence d'acide nucléique encodant un codeur bidirectionnel, cette cassette d'acide nucléique comprenant en outre une unité de transcription de base liée, en ce qui concerne l'effet, à la séquence encodant le marqueur bidirectionnel, et cette cassette d'acide nucléique comprenant en outre une séquence inductible d'accroissement ou d'activation reliée à l'unité de transcription de base d'une manière telle que, lors de l'induction de la séquence d'accroissement ou d'activation, la séquence d'acide nucléique encodant le marqueur bidirectionnel est exprimée, cette séquence inductible d'accroissement ou d'activation provenant d'un gène associé à une activité d'une partie du métabolisme. Cette séquence inductible d'accroissement ou d'activation provenant d'un gène associé au métabolisme fait l'objet de l'invention, de même que son application dans une méthode de sélection pour mutants. De plus, l'invention concerne un gène régulateur xlnR qui encode un régulateur activateur d'une séquence inductible d'accroissement ou d'activation, et l'application de ce gène ou de son produit d'expression, ou les deux, dans la surexpression de protéines ou de peptides homologues ou hétérologues. Des mutants de knock-out dans lesquels le gène en question est absent ou rendu inactif et des mutants ayant une capacité de fixation d'ADN augmentée ou diminuée font également l'objet de l'invention.
Patent CA-2228812-C (CA)
Inventor: SCHONHOFFER HELMUT
IPC: A61F2/30
Filed: 1997-05-22
Granted: 2005-11-15
Abstract: Cet implant est constitué de deux pièces terminales (1, 2) qui s'appuient sur les vertèbres adjacentes et d'une pièce centrale intermédiaire (3) reliée à une des pièces terminales par un filetage (4). La longueur totale de l'implant peut être modifiée par mise en rotation de la pièce centrale (3). Les pièces terminales (1, 2) forment des manchons tubulaires (5', 5'') avec des parois traversées par des passages (6). Les manchons (5', 5'') s'emboîtent axialement l'un dans l'autre et les pièces terminales (1, 2) coulissent axialement l'une dans l'autre et sont assujetties de façon à ne pas tourner l'une par rapport à l'autre autour de l'axe du manchon. Le filetage (4) est situé entre la pièce centrale (3) et la pièce terminale (1) à laquelle il est raccordé. La pièce centrale (3), qui peut tourner dans le filetage (4), sert de butée axiale pour l'autre pièce terminale (2).
Patent CA-2234809-C (CA)
Title: Air purging circulator
Inventor: RUHNKE JOHN
IPC: F24D19/08
Filed: 1998-04-14
Granted: 2003-07-01
Abstract: An air purging circulator is provided with a reservoir on the suction side of an impeller chamber in a circulation pump, to allow circulating water to reduce its velocity, and remove air from the lowest pressure point in the system, the suction side of the circulator, where the least amount of dissolved air is present in the circulating water, so that entrained air in the water is released, and vented from the system. The flanged inlet and outlet apertures of the pump housing are axially aligned, and preferably are located at one end of the pump housing opposite from the motor, to allow convenient installation in retrofit of existing systems.      Separation media, such as marbles, wire mesh, or crumpled wire, to further slow the water flow and enhance separation of the air from the water, can be provided in the reservoir.
Patent CA-2236223-C (CA)
Inventor: STRATFORD MALCOLM
IPC: A01N63/50
Filed: 1996-10-30
Granted: 2002-08-06
Abstract: Cette composition, conçue pour combattre les champignons, est caractérisée en ce qu'elle comprend au moins une enzyme lytique de paroi cellulaire de champignon ainsi qu'une substance naturelle affectant la membrane de la cellule microbienne, à une concentration efficace. De préférence, la composition consiste en un produit alimentaire.
Patent CA-2238474-C (CA)
Inventor: SUZUKI KEITARO
IPC: C08G79/02
Filed: 1997-05-21
Granted: 2005-07-05
Abstract: A melamine polymetaphosphate having a solubility of from 0.01 to 0.10 g/100 ml in water at 25 .degree.C, a pH of from 2.5 to 4.5 in the form of a 10 wt.% aqueous slurry at 25 .degree.C and a melamine content of from 1.0 to 1.1 mol per mol of phosphorus atom. A process for producing such a melamine polymetaphosphate, which comprises the following steps (a) and (b): (a) a step of mixing melamine, urea and an aqueous orthophosphoric acid solution containing at least 40 wt.% of orthophosphoric acid, in such a ratio that melamine is from 1.0 to 1.5 mol per mol of orthophosphoric acid and urea is from 0.1 to 1.5 mol p er mol of orthophosphoric acid, at a temperature of from 0 to 140 .degree.C, to form a reaction mixture, and stirring the reaction mixture at a temperature of from 0 to 140 .degree.C, while removing water, t o obtain a powdery product of a double salt of orthophosphoric acid with melamine and urea; and (b) a step of calcining the powdery product obtained in step (a) at a temperature of from 240 to 340 .degree.C for from 0.1 to 30 hours, while preventing agglomeration, to obtain a melamine polymetaphosphate.
Patent CA-2245476-C (CA)
Title: Apparatus and method for blending and fabricating personalized lipstick
Inventor: SWAAB MARY
IPC: A61K8/00
Filed: 1998-08-25
Granted: 2004-08-03
Abstract: An apparatus and method for custom blending and fabricating lipstick to the specific demands of individual customers. The present invention provides a kit which enables a user to blend various pigments to arrive at a very specific shade, and then blend the desired shade with a specific base to result in a desired consistency of lipstick, and which also allows the blended bases and pigments to be heated to a liquefied form and poured into a mold for hardening.     Upon cooling and hardening, a conventional lipstick case can be attached to the lipstick for removal from the mold and use by the customer. The present invention therefore not only allows a user to quickly attain the specific shade and consistency of lipstick desired, but also eliminates the time consuming and unsatisfactory process of visiting multiple stores having expansive inventories of variously shaded and textured lipsticks.
Patent CA-2247535-C (CA)
Inventor: GEMRA RICHARD J
IPC: H05K5/02
Filed: 1996-11-04
Granted: 2002-04-30
Abstract: Ce boîtier monocoque servant à abriter un équipement électronique, par exemple dans un central de télécommunications, présente des panneaux latéraux (10, 11), supérieur (12) et inférieur (13) en tôle ondulée. Ces panneaux comprennent une enveloppe continue pour la structure et constituent eux-mêmes le support de structure pour les rayons (33) destinés à l'équipement électronique et pour l'équipement électronique monté dans ces rayons. Ces derniers sont directement supportés par des éléments à vis (35) dans une ondulation des panneaux latéraux (10, 11). Aucun montant, support de châssis ou attache supplémentaire n'est nécessaire. La structure obtenue est simple à fabriquer et assure une résistance améliorée aux tremblements de terre.
Patent CA-2247643-C (CA)
Inventor: MONTGELARD MICHEL
IPC: A47J45/07
Filed: 1998-09-17
Granted: 2006-06-20
Abstract: A removable holding device for containers includes two clamp members mounted on a holding body, one of the members being mobile in translation relative to the holding body. A lever mounted on the holding body pivots between a deployed position and a position retracted inside the holding body. A link blade between the lever and the mobile member displaces the mobile member in translation when the lever pivots. The lever has at least one lateral wing portion forming an unlocking button projecting on one side of the holding body when the lever is in the retracted position.
Patent CA-2248792-C (CA)
Title: Methods for measurement of lymphocyte function
Inventor: WIER MARJORIE L
IPC: G01N33/553
Filed: 1997-03-24
Granted: 2008-01-08
Abstract: A method for measuring the responses of sets or subsets of lymphocytes to mitogens or antigens in a sample includes incubating a population of cells with a mitogen or antigen, separating the desired subset of cells by means of the interaction of a specific binding reagent that is attached to the solid phase with a cell surface determinant that is present on the cell subset of interest, lysing the separated cells, and measuring an intracellular component that is increased if the cells have responded to the stimulus. The method provides a convenient, simple, and reliable method for measuring immune function in a variety of conditions.
Patent CA-2251620-C (CA)
Title: Passive venting for pump dispensing device
Inventor: HARDY MICHAEL EARL
IPC: B05B11/00
Filed: 1997-04-11
Granted: 2007-09-25
Abstract: A manually operated pump dispensing device is provided for dispensing a liquid product. The manually operated pump dispensing device includes a container (10) for storing the liquid product, a dispensing pump (30) and a gas-permeable/liquid-impermeable vent (70). The container (10) has an interior chamber (12) and an exterior that is exposed to the environment. The dispensing pump (30) is attached to the container (10) in fluid communication with the liquid product. The dispensing pump (30) has a discharge orifice (40) and an actuator (50). The gas-permeable/liquid-impermeable vent comprises a venting module (82) that includes a membrane (84) and a support frame (86). The membrane (84) is gas-permeable/liquid-impermeable and is affixed onto the support frame (86) such that the membrane surrounds the support frame. The vent allows for communication between the interior chamber and the environment, thereby passively venting the container.
Patent CA-2252545-C (CA)
Title: Differential order video encoding system
Inventor: MUSIC JOHN D
IPC: H04N19/593
Filed: 1997-05-02
Granted: 2004-07-13
Abstract: A television communications method and system particularly suitable for high definition, with narrow-band applications as for specialized broadcasting systems and video links using a block coding procedure to produce a system not wasteful of bandwidth caused by transmitting redundancies from multiple sources which do not contribute to picture quality. A differential order video encoding method (DOVE) provides a video coding scheme based on the need for true high-quality video with real-time TV encoding (14) and delivery in fifty percent of the bandwidth of the 4.5 MHz vestigial sideband suppressed television system in universal use.      Efficient coding algorithms, based on the finding and eliminating multiple source redundancies, characterizes the redundancies and creates, in real-time, an efficient set of codes for encoding (25) only the information that is different, eliminating the need for full 4.5 MHz bandwidth.
Patent CA-2257506-C (CA)
Title: Weight-lifting apparatus and method
Inventor: ROTH MARK R
IPC: A63B21/075
Filed: 1999-01-19
Granted: 2007-11-27
Abstract: A weight-lifting apparatus includes a plurality of weights each having a central hole and a slot extending from the central hole to a perimeter of the associated weight, the slot having a width less than the diameter of the central hole. The apparatus further includes a shaft having opposing ends defining a diameter about equal to the central holes, and a sleeve positioned on the shaft. The shaft is shaped to rotatably engage the central holes and is rotatable to different positions. The shaft further has a plurality of recessed surfaces on the opposing ends corresponding to the different positions that extend different longitudinal lengths, the recessed surfaces defining with other surfaces on the shaft a reduced dimension about equal to the width of the slot. Further, the shaft and the weights are configured so that by rotating the shaft, the recessed surfaces are selectively positioned to allow the shaft to slide along one or more of the slots, thus selectively releasing the weights. A method related to the above apparatus includes providing a weight-lifting apparatus having a plurality of weights and a shaft shaped to selectively engage one or more of the weights, rotating the shaft to selectively engage a desired number of the weights, and lifting the weight-lifting apparatus with the selected weights held on the shaft. A person using the weight-lifting apparatus can easily rotate the shaft to select a desired number of weights without interrupting their exercise routine.
Patent CA-2258658-C (CA)
Title: Suction and irrigation handpiece and tip with retractable splash shield
Inventor: SAKAL ROBERT
IPC: A61H35/00
Filed: 1997-04-03
Granted: 2005-06-07
Abstract: An apparatus for irrigating a local irrigation site includes a suction/irrigation tip that is removably connected to a suction/irrigation handpiece. The tip has an irrigation tube for directing irrigation liquid to the irrigation site, and a suction tube coaxially aligned within the irrigation tube. The handpiece pumps irrigation liquid from an external reservoir, through the annular space between the irrigation tubes and the suction tube to the irrigation site. Suction is applied to the site through the central suction lumen which has a large unobstructed opening to reduce clogging. A flexible splash shield, slidably mounted to the tip, is sonically shaped and extends distally from a collar to a rim. The rim is sized to fit around and about the local site.
Patent CA-2260413-C (CA)
Title: Terpenoid lactone compounds and their production process
Inventor: NISHIDA HIROYUKI
IPC: C12P17/06
Filed: 1999-01-27
Granted: 2002-04-16
Abstract: This invention provides terpenoid lactone compounds, and processes for producing the terpenoid lactone compounds, which comprise cultivating Oidiodedron griseum FERM BP-5778 and then isolating the terpenoid lactone compounds from the fermentation broth. The present invention also provides a pharmaceutical composition comprising the terpenoid lactone compound, which is useful in the treatment of IL-1 and TNF mediated diseases or the like.
Patent CA-2260798-C (CA)
Title: Tampon having a resilient member and a method of forming the tampon
Inventor: FOX DONALD GEORGE
IPC: A61F13/22
Filed: 1997-07-09
Granted: 2006-10-03
Abstract: A tampon is disclosed which is useful in preventing premature leakage of body fluid from a woman's vagina especially during her menstrual period. The tampon includes an absorbent and a resilient member. The resilient member is positioned on or within the absorbent and both members are rolled or formed into an elongated softwind having a first end and a second end. The softwind is folded upon itself such that the first and second ends are aligned adjacent to one another and the softwind contains at least two folds therebetween. The softwind is compressed into an elongated pledget having an insertion end and a trailing end. The resilient member is capable of expanding at least a portion of the pledget so as to prevent premature leakage of body fluid when inserted into a woman's vagina. The tampon further includes a withdrawal string for removing the tampon from a woman's vagina. The withdrawal string is attached to the first and second ends of the softwind. A method of forming a tampon is also disclosed.
Patent CA-2260926-C (CA)
Title: Illudin analogs useful as antitumor agents
Inventor: MCMORRIS TREVOR C
IPC: A61K31/36
Filed: 1997-07-14
Granted: 2007-11-20
Abstract: The present invention provides illudin analogs of general formula (I) where R1 is (CH2)n-X-Y or H; n is 0 to 4; X is O or S or N or absent; and Y is an optionally substituted (C1-C8)alkyl, (C6-C10)aryl, (C6-C10)aryl(C1-C4)alkyl or cyclo(C3-C6)alkyl optionally comprising one or more heteroatoms; a monosaccharide, an amino acid residue, or H when n is 2-4; R2 is absent; or R1 and R2 together comprise a 5-- 7-membered cyclic ring; R3 is (C1-C4)alkyl or H; R4 is H, SCH2CO2(C1-C4)alkyl, O-(C5-C12)aryl or -S-(C5-C12)aryl; R5 is H, OH or absent; R6 is (C1-C4)alkyl or absent; R7 is OH or OSi((C1-C4)alkyl)3; or R6 and R7 together are ethylenedioxy;  R8 is optionally substituted (C1-C4)alkyl; and the bonds represented by -----are individually present or absent. The invention further provides dimers comprising analogs for formula (I).
Patent CA-2265095-C (CA)
Inventor: STADLER HEINZ
IPC: A61K31/00
Filed: 1999-03-08
Granted: 2008-07-22
Abstract: The present invention is concerned with pyrazolopyrimidines and pyrazolotriazines of the general formulae   and their pharmaceutically acceptable salts.   Surprisingly, these compounds have a selective affinity to 5HT-6 receptors.  They are accordingly suitable for the treatment and prevention of central nervous disorders such as, for example, psychoses, schizophrenia, manic depressions, depressions, neurological disorders, memory disorders, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease and Huntington's chorea.
Patent CA-2267366-C (CA)
Title: Process for generating voltage pulse sequences and circuit assembly therefor
Inventor: VESER ALWIN
IPC: H05B41/28
Filed: 1998-06-24
Granted: 2006-01-10
Abstract: An electric circuit assembly for generating voltage pulse sequences for the operation of dielectrically inhibited discharges, comprising a series circuit provided with an oscillating circuit induction coil (TR2-A) and a controlled switch (T1), a pulse generator (OS) controlling said switch (T1), a current valve (D1) mounted in parallel to said switch (T1), a feedback capacitor (C2) also mounted in parallel to said switch (T1), an element (TR2-B, a", b") for coupling a lamp (La1) to at least one dielectrically inhibited electrode and optionally a feedback buffer capacitor (C1) mounted in parallel to said series circuit provided with said oscillating circuit induction coil (TR2-A) and said controlled switch (T1). The coupling element of a lamp particularly includes two terminals (a", b") and the secondary winding (TR2-B) of an autotransformer (TR-2) mounted between a first pole of said switch (T1) and the associated terminal (a"), wherein the primary winding (TR2-A) of said autotransformer (TR2) acts as an oscillating circuit induction coil. The second terminal (b") is connected to the second pole of said switch (T1). In operation, said switch (T1) opens and closes alternately according to the control signal rate of the pulse generator (OS), in order to generate a sequence of voltage pulses separated by interruption times at the dielectrically inhibited electrodes of a lamp connected to the terminals (a", b").
Patent CA-2268244-C (CA)
Title: Ensemble circuit electronique resistant aux chocs
Inventor: WALSH BRENDAN M
IPC: H05K5/02
Filed: 1997-10-09
Granted: 2002-12-10
Abstract: L'invention concerne un ensemble circuit électronique (10) résistant aux chocs dans lequel un circuit électronique est placé dans une capsule (14) en contact avec une enveloppe (18, 22) l'entourant dans une position d'amortissement de chocs. La capsule peut présenter plusieurs arêtes (16, 16a, 16b), ailettes (24) ou protubérances (70) prenant appui sur l'enveloppe. La capsule peut comprendre une matière d'absorption (14f) de chocs disposée contre l'enveloppe pour protéger le circuit des vibrations, ainsi qu'une matière de support (14e) de structure destinée à protéger le circuit contre les contraintes. L'ensemble circuit (10) peut comporter un condensateur (34) permettant d'emmagasiner un signal électrique et des circuits de base de temps afin de libérer l'énergie emmagasinée, après un délai prédéterminé. L'ensemble circuit (10) peut faire partie d'un ensemble transducteur-circuit (55) comprenant un module (58) de transducteur permettant de convertir une énergie d'onde de choc en énergie électrique destinée au circuit électronique, l'énergie libérée pouvant être convertie en un signal d'initiation de détonation. L'ensemble transducteur-circuit (55) peut faire partie d'un détonateur (100) recevant un signal d'initiation non électrique et détonant après le délai déterminé par le circuit électronique. Le logement (112) du détonateur ou une gaine (22) éventuelle sert d'enveloppe à l'ensemble transducteur-circuit (55).
Patent CA-2277775-C (CA)
Inventor: ALLINGHAM PAUL
IPC: B01D46/02
Filed: 1998-10-22
Granted: 2007-01-09
Abstract: The disclosed apparatus is a filter bag cage (10) which is modularly constructed from end caps (12, 14), circumferential rings (18) (circular or other shapes), and longitudinal wires (16) which are individually manufactured with fastening joints (20) to allow for later assembly. These components may be subsequently shipped and stored as an unassembled bundle and not assembled until reaching the point of use.
Patent CA-2279618-C (CA)
Inventor: ZUNDA CHARLES
IPC: B65D1/02
Filed: 1999-08-04
Granted: 2007-01-16
Abstract: A container shaped as a toy raft has a body wall with a member protruding therefrom for mounting a character toy on the member. A character toy has a cavity formed in an exterior portion thereof for positioning the character toy on the member. A toy combination is the character toy mounted on the body wall of the container by the cavity of the character toy being positioned on the member of the container.
Patent CA-2285691-C (CA)
Title: Probes for the diagnosis of infections caused by bacteroides fragilis
Inventor: KESHI HIROYUKI
IPC: C12R1/01
Filed: 1998-03-23
Granted: 2007-05-08
Abstract: The DNA from the bacteria Bacteroides fragilis is extracted, then completely digested with restriction enzyme HindIII, followed by cloning into a suitable vector to select a probe comprising DNA which is essentially contained in Bacteroides fragilis , then the sequence of the probe is elucidated.
Patent CA-2287881-C (CA)
Title: Vitamin d3 analogs with bis c-20 side chains
Inventor: MANCHAND PERCY SARWOOD
IPC: C07C401/00
Filed: 1998-04-22
Granted: 2008-09-09
Abstract: This invention provides Vitamin D3 analogs of the Formula (1) wherein: X is H2 or CH2; Y is hydrogen, hydroxy or fluorine; Z is hydroxy; R1 and R2 are a(C1-C4) alkyl or fluoroalkyl, or R1 and R2 together with C25 form a (C3-C6) cycloalkyl or cyclofluoroalkyl; R3 and R4 are a (C1-C4) alkyl or fluoroalkyl, or R3 and R4 together with C25' form a (C3-C6) cycloalkyl or cyclofluoroalkyl; A is a single bond or a double bond; B1 is a single bond, an E-double bond, a Z-double bond or a triple bond; and B2 is a single bond, an E-double bond, a Z-double bond or a triple bond; and prodrugs thereof; intermediates and methods for preparation of these analogs, pharmaceutical compositions containing such analogs and methods for treatment of osteoporosis, hyperparathyroidism autoimmune diseases and for the treatment and prevention of neoplastic diseases.</SDOAB >
Patent CA-2288092-C (CA)
Inventor: RAITH ALEX K
IPC: H04W4/90
Filed: 1998-04-06
Granted: 2008-07-22
Abstract: Le traitement des appels d'urgence, par exemple les appels du 911, devrait se faire d'une manière accélérée. L'invention décrit diverses techniques qui permettent, dans les systèmes de radiocommunication, d'accélérer l'accès au système quand ce dernier traite les appels d'urgence. Par exemple, le verrouillage sur un canal de commande, le contenu du message d'émission et les règles de retransmission sont modifiées afin de diminuer le temps d'accès.