baber/WOPTO huggingface dataset:
Patent EP-4138638-A1 (EP)
Inventor: DE BRAGANCA KEVIN C
IPC: A61B5/16
Filed: 2021-04-21
Abstract: Systems for assessing and documenting changes in handwriting neurologic toxicity adverse events associated with a medical treatment (e.g., immune effector cell therapy) comprise a handwriting neurotoxicity grading criteria that defines the symptoms of at least one adverse event including micrographia, dysgraphia and agraphia. The handwriting neurotoxicity grading criteria may be included in a system for assessing immune effector cell associated movement and neurocognitive disorder, that comprises grading criteria for one or more of the symptom domains: handwriting impairment, gait impairment, other movement abnormalities of extremities, impairment in ability to perform ADLs, and impairment in expression or motivation.
Patent EP-4154194-A1 (EP)
Inventor: STEINMETZ BERNHARD
IPC: G06N20/00
Filed: 2021-05-20
Abstract: The present invention relates to prediction of properties of a chemical mixture. A computer- implemented method is proposed for training a data-driven model for predicting properties of a chemical mixture. The method comprises the steps of obtaining data comprising history and/or calibration data of a plurality of chemical mixture recipes and properties of each chemical mixture recipe, each chemical mixture recipe comprises two or more ingredients, assigning at least one ingredient in each chemical mixture recipe to one of pre-defined substance clusters, each pre-defined substance cluster representing one ingredient or a group of ingredients having similar chemistry, revising each chemical mixture recipe by replacing the at least one ingredient with the assigned pre-defined substance cluster, and providing the revised chemical mixture recipes, together with the properties of the chemical mixture recipes, to a machine learning process in order to train a data-driven model, which is usable for predicting characteristics of properties of a new chemical mixture.
Patent EP-4164585-A1 (EP)
Inventor: FIORE SIMONA
IPC: A61K8/73
Filed: 2021-06-11
Abstract: La présente invention concerne un gel hydroalcoolique comprenant au moins 70 % en poids d'alcool, entre 5 et 10 % en poids d'une composition d'huile, entre 0,15 et 6 % en poids d'un agent gélifiant et entre 0,01 et 0,1 % en poids d'un agent d'ajustement du pH, l'agent gélifiant étant constitué de 0,05 à 2,0 % en poids d'un carbomère et de 0,1 à 4,5 % en poids d'une composition de polymère de cellulose. Ledit gel hydroalcoolique est unique en ce qu'il détruit les micro-organismes et les virus, humidifie la peau, ne laisse pas de résidu huileux, ni de sensation collante sur la peau, et adhère fermement à la peau (même après lavage) ce qui permet d'obtenir un effet désinfectant à long terme.
Patent EP-4165568-A1 (EP)
Inventor: SCHEUERMANN ENRICO B
IPC: G06Q10/06
Filed: 2021-06-11
Abstract: The invention relates to a method for controlling actions of a mobile entity on a field management unit. The method comprises providing a database, wherein georeferenced boundaries of field management units are stored in the database, providing an assessment unit, determining a current position of a mobile entity by using a global navigation satellite system receiver for establishing a Position of the mobile entity, determining a current field management unit, in which the mobile entity is located, based on the current Position of the mobile entity and based on the georeferenced boundaries of the field management units stored in the database, determining one or more adjacent field management units, which are arranged adjacent to the current field management unit, based on the current Position of the mobile entity and/or on the current field management unit and based on the georeferenced boundaries of the field management units stored in the database.
Patent EP-4165701-A1 (EP)
Title: Method for providing a cleaned gas-diffusion layer for electrochemical applications
Inventor: BANGEL DIETER
IPC: H01M4/88
Filed: 2021-06-09
Abstract: The invention relates to a method for providing a cleaned gas-diffusion layer (1) for electrochemical applications, comprising the steps of: providing (100) a gas-diffusion layer (1) in such a way that a first side (2) of the gas-diffusion layer (1) is arranged on a first vacuum conveyor belt (10); cleaning (200) an exposed, second side (3) of the gas-diffusion layer (1), opposite from the first side (2) of the gas-diffusion layer (1); transferring (300) the partly cleaned gas-diffusion layer (1) to a second vacuum conveyor belt (13) lying partly opposite the first vacuum conveyor belt (10), wherein the first vacuum conveyor belt (10) and the second vacuum conveyor belt (13) have a transfer region (B), in which the gas-diffusion layer (1) is transferred from the first vacuum conveyor belt (10) to the second vacuum conveyor belt (13) such that the first side (2) of the gas-diffusion layer (1) is exposed, and cleaning (400) the first side (2) of the gas-diffusion layer (1).
Patent EP-4168044-A1 (EP)
Title: Swine influenza a virus vaccine comprising two distinct rna replicon particles
Inventor: MOGLER MARK A
IPC: A61P31/16
Filed: 2021-06-18
Abstract: The present invention relates to an immunogenic composition comprising first and second RNA replicon particles. The first RNA replicon particle comprises a nucleic acid construct comprising first and second nucleic acid sequences encoding first and second hemagglutinin (HA) antigens of a Swine influenza A virus (IAV-S). The first HA antigen is a of the A/swine/Gent/1/1984-like H3N2 (Gent/84) lineage, and the second HA antigen is of the A(H1N1)pdm09 (pdm09) lineage. The second RNA replicon particle comprises a nucleic acid construct comprising third and fourth nucleic acid sequences encoding third and fourth HA antigens of IAV-S. The third HA antigen is of the A/swine/Scotland/410440/1994-like H1 hu N2 (Scot/94) lineage, and the fourth HA antigen is of the Eurasian avian-like H1 av N1 (EA) lineage. In other embodiments, the present invention relates to a vaccine, which may be used against influenza A virus infection, and comprising the immunogenic composition. Further provided are methods of making the vaccine and use of the vaccine.
Patent EP-4171519-A1 (EP)
Title: Soft gelatin capsules
Inventor: MOSCOSO DEL PRADO JAIME
IPC: A61K31/00
Filed: 2021-06-24
Abstract: The present invention relates to soft gelatin capsules, to the use of the soft gelatin capsule as a food supplement, dietary supplement and health supplement, to a process for preparing the soft gelatin capsule, to the soft gelatin capsule for use in medicine and to the soft gelatin capsule for use in the treatment and/or prevention of a disease or pathology.
Patent EP-4149313-A1 (EP)
Title: Sole structure for article of footwear
Inventor: CHAN WESLEY K
IPC: A43B3/00
Filed: 2021-05-11
Abstract: A sole structure for an article of footwear includes a bladder having a plurality of tapered chambers including (a) a series of first tapered chambers tapering from a first end on a medial side of the bladder to a second end on a lateral side of the bladder, and (b) one or more second tapered chambers tapering from a first end on the lateral side of the bladder to a second end on the medial side of the bladder. Each of the one or more second tapered chambers is interposed between adjacent ones of the first tapered chambers. The sole structure also includes a chassis disposed on a first side of the bladder and having a plurality of first ribs each disposed between adjacent ones of the first tapered chambers and the second tapered chambers.
Patent EP-4162162-A1 (EP)
Title: Vacuum system apparatus and method
Inventor: KAILASAM SIVABALAN
IPC: F04D29/58
Filed: 2021-06-08
Abstract: Aspects of the present invention relate to a vacuum system (1). The vacuum system (1) includes a vacuum pump (3); and a heat exchanger (7) for receiving a heat transfer fluid. The heat transfer fluid comprising a gas. The heat exchanger (7) is thermally coupled to the vacuum pump (3) and is operable to absorb thermal energy from the vacuum pump (3). Aspects of the present invention also relate to a method of operating a vacuum system (1); and a controller (31) for controlling operation of a vacuum system (1).
Patent EP-4162031-A1 (EP)
Inventor: NEUMAYER BERNHARD
IPC: C12N9/02
Filed: 2021-06-08
Abstract: The present invention relates to a method of converting 3-keto-DON into 3-epi-DON, reducing the content of DON in a composition comprising DON or of reducing the toxicity of a composition comprising DON as well as a method for converting a trichothecene comprising a 3-oxo group into a trichothecene comprising a 3-hydroxy group using one or more polypeptide(s) comprising or consisting of SEQ ID NO. 1 or a sequence having a sequence identity of at least 72.0 % to SEQ ID NO. 1. Also envisioned are feed or food additives or feed or food as well as pharmaceutical compositions comprising one or more polypeptide(s) comprising or consisting of a sequence of SEQ ID NO. 1 or a sequence having a sequence identity of at least 72.0 % to SEQ ID NO. 1 as well as the manufacture thereof. Encompassed are further polypeptide(s) comprising or consisting of a sequence of SEQ ID NO. 1 or a sequence having a sequence identity of at least 88.5 % to SEQ ID NO. 1. Also envisioned are host cells or plants.
Patent EP-4164486-A1 (EP)
Title: Procédé pour déterminer une concentration réelle d'un substrat à l'aide d'un ensemble de biocapteurs auto-calibres et dispositif pour la mise en ?uvre du procédé
Inventor: ZEBDA ABDELKADER
IPC: A61B5/1495
Filed: 2021-06-11
Abstract: La présente invention porte sur un Procédé pour déterminer, de façon stable au cours du temps, une région dans laquelle se situe la concentration réelle, dans un milieu, d'un substrat (S1) constitué par toute molécule susceptible de subir une oxydo-réduction catalysée par un catalyseur, caractérisé par le fait qu'il comprend les étapes suivantes : a) prendre au moins un groupe d'au moins deux biocapteurs, chaque biocapteur présentant une courbe d'étalonnage du signal induit par la réaction d'oxydo-réduction : les biocapteurs d'un groupe présentant des parties initiales identiques de leurs courbes d'étalonnage jusqu'à une valeur de concentration en substrat (S1), dite concentration de séparation (CS), à partir de laquelle la mesure du signal diffère d'un biocapteur à l'autre du groupe; et lorsque plus d'un groupe est présent, les biocapteurs des différents groupes présentant des courbes d'étalonnage différentes, sans présenter de parties initiales identiques; b) mettre les biocapteurs en contact avec ledit milieu; c) mesurer le signal induit par la réaction d'oxydation ou de réduction pour chacun des biocapteurs du ou des groupes; d) comparer toutes les valeurs des signaux donnés par tous les biocapteurs, et suivre la méthode décrite dans la description.
Patent EP-4181670-A1 (EP)
Title: Method for raising fish in a recirculated aquaculture system
Inventor: DETHLEFSEN MARKUS WIED
IPC: A01K61/80
Filed: 2021-07-15
Abstract: The present invention relates to a method of raising fish in a recirculated aquaculture system (RAS), the RAS comprising a fish holding unit (2) in fluid communication with a water supply (3), the fish holding unit containing a volume of water defining a water depth, the water having an osmotic concentration, an oxygen concentration, a temperature, and a pH, the method comprising the steps of: providing a flow of non-recirculated water to the water supply, the non-recirculated water being different from the water in the fish holding unit with respect to at least one of the osmotic concentration, the oxygen concentration, the CO2 concentration, the N2 concentration, the NH4 + concentration, the temperature and the pH, providing feed pellets (31), adding the feed pellets to the non- recirculated water and hydraulically transporting the feed pellets to the fish holding unit. The method allows a more efficient operation of a RAS facility. The invention also relates to a RAS facility.
Patent EP-4188318-A1 (EP)
Inventor: GU XUELAN
IPC: A61K36/185
Filed: 2021-07-14
Abstract: La présente invention concerne une composition de soins personnels. En particulier, la présente invention concerne une composition de soins personnels destinée à fournir des avantages contre l'hyperpigmentation. En conséquence, la présente invention concerne une composition de soins personnels comprenant : a. de l'atractylénolide-I ou une source d'atractylénolide-I ; et b. un acide gras hydroxy dont le nombre d'atomes de carbone est de 12 à 20.
Patent EP-4196404-A1 (EP)
Inventor: HIRZ DIETHELM
IPC: B65D55/06
Filed: 2021-08-03
Abstract: Die Erfindung betrifft eine Vorrichtung zum gezielten Auftrennen einer die Verbindung zwischen einem Deckel und einem Behälter oder zwischen Bauteilen eines Behälters absichernden Plombe sowie ein System bestehend aus einem Deckel, Behälter, Plombe und einer Auftrennvorrichtung. Die Auftrennvorrichtung ermöglicht die Öffnung eines mit einer Plombe gesicherten Verschlusses ohne zusätzliche manuelle Tätigkeiten und vergleichmäßigt den Vorgang des Auftrennens einer Plombe.
Patent EP-4197138-A1 (EP)
Inventor: WIGARD JEROEN
IPC: H04L1/18
Filed: 2021-07-14
Abstract: Systems, methods, apparatuses, and computer program products for conditional hybrid automatic repeat request (HARQ) acknowledgement (ACK). For instance, a user equipment (UE) may estimate, during reception of a downlink transmission with x repetitions, an amount of extra energy that may be needed to help ensure successful decoding. The UE may then express this estimate as a quantity of repetitions (y) needed for successful reception, and may inform the radio access network (RAN) of this quantity (e.g., at least one round-trip time (RTT) before the last repetition of the x repetitions is sent). The RAN may handle this message as a conditional positive ACK. The RAN may send the quantity of repetitions y, and may implicitly assume an ACK for that TBS after sending the y repetitions. The RAN may send the next transport blocks (TBS) for that HARQ process after completing transmission of the y repetitions.
Patent EP-4181944-A1 (EP)
Title: Inhaled interferon-beta for improving outcome in sars-cov-2 infected patients
Inventor: MARSDEN RICHARD
IPC: A61P31/14
Filed: 2021-07-19
Abstract: The present invention relates to use of inhaled interferon-beta for use in preventing or reducing the severity of lower respiratory tract (LRT) illness in a patient infected with a coronavirus capable of causing acute respiratory distress syndrome, e.g. preventing or reducing the severity of LRT illness in COVID-19 patients infected with SARS-CoV-2. Targeting of such treatment to promote recovery based on simple and quick breathlessness scoring is proposed which is applicable in both the home and hospital environments.
Patent EP-4188761-A1 (EP)
Inventor: SCHMIDT KLAUS
IPC: B60T8/175
Filed: 2021-07-28
Abstract: L'invention concerne deux procédés pour la commande de l'entraînement d'un véhicule automobile à entraînement de roue individuel sur deux roues du véhicule et avec un premier capteur au moyen d'une unité de régulation à boucle fermée, l'unité de régulation comprenant une unité d'évaluation et une unité de régulation à boucle fermée. L'invention concerne également un dispositif de commande de l'entraînement et une chaîne cinématique d'un tel véhicule automobile ainsi que le véhicule automobile lui-même.
Patent EP-4103179-A1 (EP)
Title: Combination therapy for treating amyotrophic lateral using pridopidine and another active agent
Inventor: GEVA MICHAL
IPC: A61K39/00
Filed: 2021-02-13
Abstract: Provided herein is a method for treating a human subject afflicted with ALS by administering to the subject a therapeutically effective amount of pridopidine or pharmaceutically acceptable salt thereof in combination with sodium phenylbutyrate (PB), tauroursodeoxy cholic acid, combination of sodium phenylbutyrate (PB )/tauroursodeoxy cholic acid (i.e. AMX0035), Zilucoplan, Verdiperstat, CNM-Au8 nanocrystalline gold, SLS-005 (trehalose), IC14 or combination thereof as combination or add-on therapy.
Patent EP-4106279-A1 (EP)
Title: Iot connection system, information processing method, and computer program
Inventor: MATSUMURA JUN
IPC: H04L12/46
Filed: 2021-02-03
Abstract: Attractive services are provided by freely interconnecting loTs via the Internet.An loT connection system includes an loT hub and an loT router. The loT hub includes at least one of a first driver and a second driver, the first driver being used to connect the loT hub to a private cloud to which a first device is connectable, and the second driver being used to connect a second device and the loT hub, the loT router includes a third driver for connecting a third device and the loT router, and the loT hub executes a continuous connection function for continuously connecting the first device, the second device, the third device, and an loT service that is usable via the loT hub to each other, and a directory function for associating the first device, the second device, the third device, and the loT service with each other.
Patent EP-4225801-A1 (EP)
Title: Anticorps anti-idiotypiques dirigés contre des anticorps anti-gprc5d
Inventor: CHI ELLEN
IPC: C07K16/42
Filed: 2021-07-15
Abstract: Dans certains aspects, la divulgation concerne des anticorps anti-idiotypiques et des parties de liaison à l'antigène de ceux-ci qui se lient de manière spécifique à une protéine contenant GP5B83, par exemple un anticorps ou des parties de liaison à l'antigène de celui-ci. Dans certains aspects, les anticorps anti-idiotypiques et les parties de liaison à l'antigène selon la présente divulgation peuvent être utilisés dans des procédés pour détecter et quantifier des cellules exprimant des récepteurs antigéniques chimériques comprenant GP5B83.
Patent EP-4114428-A1 (EP)
Title: Polypeptides d'ulinastatine
Inventor: PAULS RICK
IPC: C07K14/81
Filed: 2021-03-05
Abstract: L'invention concerne des glycoformes de l'ulinastatine, des polypeptides de fusion de l'ulinastatine et des compositions, des mélanges et des méthodes d'utilisation associés, y compris des méthodes de production par recombinaison de polypeptides de l'ulinastatine et pour le traitement de maladies.
Patent EP-4200591-A1 (EP)
Inventor: JONG ARTHUR MARTIN
IPC: G01N15/10
Filed: 2021-08-17
Abstract: The present invention relates to a biosensor device for sensing an analyte over a period of time using particle motion, the biosensor device having a surface and a particle, wherein the particle and/or the surface are functionalized, and wherein the biosensor device has a first state in which the particle is associated with the surface and a second state in which the particle is not associated with the surface, and wherein switching between the first and second states depends on the presence, absence and/or concentration of the analyte, whereby motion characteristics of the particle change depending on the presence, absence and/or concentration of the analyte, and wherein the properties of the particle and surface are selected such that in the second state the particle is within the vicinity of the surface such that the biosensor is able to measure changes in a spatial coordinate parameter of the particle relative to the surface, wherein the particle is not conjugated to the surface.
Patent EP-4214396-A1 (EP)
Title: Procédé et système de signalisation à distance d'un ensemble de fond de trou comprenant un ou plusieurs outils de fond de trou
Inventor: MURDOCH EUAN
IPC: E21B34/02
Filed: 2021-09-14
Abstract: Un procédé de signalisation à distance d'un ensemble de fond de trou comprenant un ou plusieurs outils de fond de trou consiste à faire fonctionner un agencement de duse conçu pour commander un écoulement de fluide de production à partir d'un puits de forage afin de produire une première signature de pression dans l'écoulement de fluide, la première signature de pression définissant un signal de déclenchement pour l'outil ou les outils de fond de trou de l'ensemble de fond de trou, et la première signature de pression comprenant au moins un premier signal de pression et un second signal de pression dans l'écoulement de fluide de production dans l'ensemble de fond de trou ; et à faire fonctionner l'agencement de duse pour produire une seconde signature de pression dans l'écoulement de fluide de production dans l'ensemble de fond de trou à une période prédéterminée suivant la première signature de pression, la seconde signature de pression définissant un signal de commande permettant de commencer à faire fonctionner un ou plusieurs outils de fond de trou prédéterminés des outils de fond de trou de l'ensemble de fond de trou.
Patent EP-3998705-A1 (EP)
Inventor: SHANG WEIBING
IPC: H03K5/13
Filed: 2021-06-01
Abstract: The present disclosure provides a delay circuit and a delay structure. The circuit includes: a first delay unit configured to delay a rising edge and/or a falling edge of a pulse signal, where, an input terminal of the first delay unit receives the pulse signal, and an output terminal of the first delay unit outputs a first delay signal, and a second delay unit, configured to delay the first delay signal, where an input terminal of the second delay unit is connected to the output terminal of the first delay unit, and an output terminal of the second delay unit outputs a second delay signal. A delay time between a rising edge of the second delay signal and the rising edge of the pulse signal is denoted as a rising edge delay time; a delay time between a falling edge of the second delay signal and the falling edge of the pulse signal is denoted as a falling edge delay time; a variation value, varying with a first parameter, of the rising edge delay time and/or the falling edge delay time is within a first range, and the first parameter includes at least one of the following: manufacturing process, power supply voltage wave, or working temperate of the delay circuit.
Patent EP-4125995-A1 (EP)
Inventor: RIOULT MARIKA G
IPC: A61K38/16
Filed: 2021-03-30
Abstract: Une irradiation aux rayons gamma et par faisceau électronique permet une stérilisation efficace de certains peptides à auto-assemblage (y compris le RADA16 en solution) sans dégradation sensible du peptide majeur, tandis que, par exemple, un autre peptide à auto-assemblage, QLEL12, a été significativement dégradé après irradiation. La stérilisation par irradiation améliore la propriété rhéologique, par exemple, d'un hydrogel de RADA16 une fois appliqué sur un tissu à un pH physiologique. L'augmentation des propriétés rhéologiques peut entraîner une plus grande efficacité dans une variété d'applications biomédicales.
Patent EP-4214195-A1 (EP)
Title: Solid state forms of gefapixant and process for preparation thereof
Inventor: SAMEC DIJANA SKALEC
IPC: C07D239/28
Filed: 2021-09-16
Abstract: The present disclosure encompasses solid state forms of Gefapixant, in embodiments crystalline polymorphs or salts or co-crystals of Gefapixant, processes for preparation thereof, and pharmaceutical compositions thereof.
Patent EP-4189214-A1 (EP)
Inventor: JOHANSSON BENGT
IPC: F01D9/04
Filed: 2021-09-02
Abstract: A guide vane in a gas turbine engine includes an inner platform, an outer platform, and two vane airfoils extending between the inner platform and the outer platform and spaced apart from each other. The outer platform includes a front hook and a rear hook. A front locking feature and a rear locking feature are disposed on the front hook and the rear hook, respectively. Each of the two vane airfoils includes a pressure sidewall and a suction sidewall meeting upstream forming a leading edge. A downstream end of the suction sidewall extends downstream further from a downstream end of the pressure sidewall forming a trailing edge. An upstream side of the inner platform of the guide vane is longer than a downstream side of an inner platform of an upstream turbine blade of the gas turbine engine.