baber/WOPTO huggingface dataset:
Patent CA-2253441-C (CA)
Inventor: SZKUDLINSKI MARIUSZ W
IPC: C12N15/16
Filed: 1996-05-08
Granted: 2013-07-16
Abstract: The invention is directed toward a human glycoprotein hormone having at least one, two, three, four or five basic amino acids in the .alpha.-subunit at positions selected from the group consisting of positions 11, 13, 14, 16, 17 and 20. The invention is also directed to a human glycoprotein where at least one of the amino acids at positions 58, 63 and 69 of the .beta.-subunit of the human thyroid stimulating hormone are basic amino acids. The invention is further directed to a modified human glycoprotein hormone having increased activity over a wild-type human glycoprotein hormone, where the modified human glycoprotein hormone comprises a basic amino acid substituted at a position corresponding to the same amino acid position in a non-human glycoprotein hormone having an increased activity over the wild-type human glycoprotein hormone. The invention is also directed to a method of constructing superactive nonchimeric analogs of human hormones comprising comparing the amino acid sequence of a more active homolog from another species to the human hormone, substituting selected amino acids in the human hormone with the corresponding amino acids from the other species, determining the activity of the substituted human hormones, and selecting superactive analogs from the substituted human hormones. The invention is also directed to nucleic acids encoding the modified human glycoprotein hormones, vectors containing those nucleic acids, and host cells containing those vectors.
Patent CA-2256309-C (CA)
Inventor: ILLIG CARL
IPC: A61P9/10
Filed: 1996-12-20
Granted: 2006-08-15
Abstract: Amidino and benzamidino compounds, including compounds of Formula (I), wherein R1-R4, R6-R9, Y, Z, n and m are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof, that inhibit a number of proteolytic enzymes are described. Also described are methods for preparing the compounds of Formula (I).
Patent CA-2258704-C (CA)
Inventor: ADAMS WILLIAM
IPC: G06Q10/00
Filed: 1997-06-18
Granted: 2002-01-01
Abstract: L'invention concerne un structure pour documents communs, destinée à être utilisée par un programme d'application (1410) et qui donne l'accès commun à un document commun (1490) au moyen d'un groupe (1460) associé au document commun (1490). Ledit groupe (1460) reçoit les messages provenant du groupe (1430, 1441, 1480) et les radiodiffusent à tous les membres du groupe (1430, 1441, 1480) dans l'ordre global. Ladite structure comporte des informations (710) sur la classe du document commun à partir desquelles un exemple de document commun peut être créé. Lesdites informations comportent des moyens pour créer une copie locale du document mis en commun (1410, 1440); des moyens permettant au programme d'application de rejoindre le groupe en tant que membre (JOIN); des moyens pour recevoir une confirmation de commande en provenance du programme d'application et pour l'envoyer au groupe sous forme de message (1432, 1442); et un moyen, répondant à la diffusion d'une confirmation de commande du groupe, pour appliquer la confirmation de commande reçue au document lorsque le programme d'application n'a pas reçu la confirmation de commande et pour appliquer la confirmation de commande d'origine lorsque le programme d'application n'a pas envoyé de confirmation de commande (1431, 1443).
Patent CA-2267630-C (CA)
Title: Nitrate esters of corticoid compounds and pharmaceutical applications thereof
Inventor: DEL SOLDATO PIERO
IPC: A61P17/00
Filed: 1997-10-02
Granted: 2008-01-08
Abstract: Compounds of the general formula B-X1-NO2 or their esters or salts, where B  has structure (1) where there may be substituents in place of the hydrogens H in the CH group or two hydrogens H2 in the CH2 group shown in the general formula; R and R' are equal or different one from the other and may be hydrogen or linear or branched alkyls having from 1 to 4 carbon atoms, preferably R = R' = CH3;  B being a corticosteroid residue; R" is -(CO-L)t-(X)t1- where t and t1 are integers equal or different one from the other and equal to 0 or 1; where L is a bivalent connecting group; X is equal to X0 where X0 = 0, NH, NR1C where R1C is a linear or branched alkyl having from 1 to 10 C atoms; or equal to X2 where X2 is equal to OH, CH3, Cl, N(-CH2-CH3)2, SCH2F, SH; X1 is a bivalent connecting bridge YO where Y is a C1-C20 alkylene.
Patent CA-2268484-C (CA)
Title: Cyclobutyl-aryloxyarylsulfonylamino hydroxamic acid derivatives
Inventor: REITER LAWRENCE ALAN
IPC: A61K31/44
Filed: 1999-04-08
Granted: 2006-02-07
Abstract: Disclosed is a compound of the formula: (See formula I) (wherein R1 is H or alkyl and Y is H or a substituent), useful in the treatment of arthritis or cancer and other diseases involving selective inhibition of matrix metalloproteinase-13.
Patent CA-2270511-C (CA)
Title: Water based crab meat extraction process with water recirculation
Inventor: FULCHER GARLAND CHRISTOPHER
IPC: A22C29/02
Filed: 1999-04-30
Granted: 2001-06-12
Abstract: An apparatus and a process for extracting crustacean meat from shells is provided. The extracting method is based on mechanical separation utilizing heated water spray within a rotating drum assembly for removal and separation of meat from shells . The water is collected, pumped to a holding tank, and is flavored with natural crab extract for recycle within the process. The apparatus includes a hammer mill for fracturing shells, a heated water bath for separating fractured shells from meat, an inclined rotating drum assembly having perforated walls and an internally located nozzle dispensing a water spray for separating meat from fractured shells, a tank having at least one water jet for separating meat from shell fragments, a vibrating dewatering apparatus for separating meat from the water, and a recirculation system for collecting, reheating, and reusing the solution of water and crab extract. The apparatus and process provides bone free crustacean meat that retains the natural crab flavor and has a low bacteria count.
Patent CA-2271544-C (CA)
Title: Method to detect bone and other connective tissue disorders in humans and animals
Inventor: ROBINS SIMON P
IPC: C07K16/00
Filed: 1990-12-28
Granted: 2006-01-17
Abstract: The invention is directed to methods to assess connective tissue, especially bone, metabolism in disease or to monitor therapy, which method comprises assessing the levels of native free collagen-derived crosslinks in biological fluids, especially urine. The method can be enhanced by concomitantly determining the levels of an indicator of bone formation in biological fluids of the same individual and assessing the differences between the degradation marker and the formation indicator. Antibodies which are specifically immunoreactive with forms of crosslinks which occur free in biological fluids are also disclosed.
Patent CA-2274017-C (CA)
Inventor: HUGHES JOHN FARRELL
IPC: B03C7/00
Filed: 1997-12-03
Granted: 2006-10-17
Abstract: L'invention concerne un procédé permettant de combattre et d'éliminer la poussière et autres particules fines déposées sur un matériau. Il comprend les étapes suivantes: i) soumettre des particules porteuses sous forme de poudre à une charge électrostatique pour conférer auxdites particules un rapport charge/masse minimum de +/- 1x10<-4>C/Kg, ii) acheminer les particules porteuses chargées en électricité statique vers le matériau, ce qui permet à la poussière et aux autres particules fines déposées sur le matériau de s'agglomérer aux particules porteuses chargées en électricité statique, et iii) éliminer les agglomérats obtenus du matériau (par exemple, par aspiration ou brossage). L'invention concerne également un appareil destiné à acheminer des particules chargées en électricité statique sur un matériau. Cet appareil comprend: a) un récipient, dans lequel sont contenues les particules chargées en électricité statique, b) des moyens permettant d'acheminer les particules du récipient vers le tapis ou tout autre tissu qui se composent i) d'un tube ou tuyau destiné à acheminer les particules porteuses vers le tapis ou tout autre tissu fin et ii) de dispositifs permettant d'expulser à grande vitesse les particules du récipient au matériau. Le tube ou le tuyau sont fabriqués en une matière telle que, lorsque les particules porteuses tombent du tube d'amenée à grande vitesse, elles se voient conférer un rapport charge/masse minimum de +/- 1x10<-4>C/Kg par friction des particules sur la paroi intérieure du tube ou du tuyau.
Patent CA-2275266-C (CA)
Inventor: YASUNAGA KAZUTOSHI
IPC: G10L19/10
Filed: 1998-10-22
Granted: 2005-06-14
Abstract: An excitation vector generator comprises a pulse vector generating section having N channels (N~1) for generating pulse vectors, a storing section for storing M (M~1)kinds of dispersion patterns every channel in accordance with N channels, a selecting section for selectively taking out a dispersion pattern from the storing section every channel , a dispersion section for performing a superimposing calculation of the extracted dispersion pattern and the generated pulse vectors every channel so as to generate N dispersion vectors, excitation vector generating section for generating an excitation vector from N dispersion vectors generated.
Patent CA-2279737-C (CA)
Inventor: SEIKE KOICHI
IPC: C08J7/052
Filed: 1999-08-05
Granted: 2004-04-27
Abstract: A decorative film for use in plastics molding, said decorative film being a laminate film prepared by outwardly and successively laminating a polyolefin film layer, a primer layer, optionally a topcoating layer and a releasable layer, said primer layer being a coating film formed from an isocyanate-curing type resin composition containing (A) a hydroxyl group-containing resin having a hydroxyl number of 30 to 200 KOH mg/g on an average and a weight average molecular weight of 1000 to 80000, (B) a polyolefin based resin and (C) a (blocked)polyisocyanate compound in such mixing amounts that a number of the isocyanate group in the component (C) is in the range of 0.1 to 0.9 per one hydroxyl group in the component (A) and that the component (B) is in the range of 1 to 90% by weight based on a total weight of the components (A), (B) and (C), and having a static glass transition temperature of 20 to 70°C , an elongation of 10% or more and a tensile strength of 0.5 kgf/mm2 or more; a process for preparing the decorative film and an injection-molded part by use of the decorative film.
Patent CA-2282407-C (CA)
Title: Methods and compositions for optimization of oxygen transport by cell-free systems
Inventor: INTAGLIETTA MARCOS
IPC: A61K38/42
Filed: 1998-02-27
Granted: 2004-10-26
Abstract: Compositions, and methods of use thereof, for use as blood substitute products comprise aqueous mixtures of oxygen-carrying and non-oxygen carrying plasma expanders and methods for the use thereof. The oxygen-carrying component may consist of and hemoglobin-based oxygen carrier, while the non-oxygen carrying plasma expander may consist of any suitable diluent.
Patent CA-2283180-C (CA)
Inventor: CAMAGNA JOHN R
IPC: H04L7/02
Filed: 1998-03-04
Granted: 2005-05-24
Abstract: A timing recovery circuit is disclosed that prevents phase error over-compensation. The timing recovery circuit includes a phase scanner for determining when phase error over-compensation has occurred and generating a signal for preventing dual phase compensation in response thereto, thereby providing an accurate recovered clock signal. The timing recovery circuit also includes a feed-forward equalizer having a plurality of taps providing coefficients for filtering and adapting the input timing recovery circuit to an input signal. The phase scanner compares the tap coefficients to generate signal for preventing phase over-compensation by the feed-forward equalizer. A phase detector is provided for sampling coefficients from the feed-forward equalizer, error signals and output data and generating a phase signal used to generating the recovered clock signal. The signal for preventing phase over-compensation is mixed with the phase signal to generate the recovered clock signal.
Patent CA-2285128-C (CA)
Title: Switch for optical signals
Inventor: GRAVES ALAN F
IPC: H04Q1/04
Filed: 1999-10-06
Granted: 2008-02-26
Abstract: A cross-connect switch for switching optical signals, in particular, Dense Wavelength Division Multiplexed (DWDM) signals is disclosed. The switch includes a switching matrix for each of the predetermined wavelengths of the DWDM signals. The switching matrices include Micro-Electro-Mechanical (MEM) systems which have optically reflective elements, typically mirrors, arranged in rows and columns for switching an incoming optical signal travelling along a row of such elements to an output port aligned with a column of the elements. The switch has input demultiplexers to split an incoming DWDM signal into its component channel wavelengths, each of which is directed to a switching matrix where it is switched to an output port and recombined into an outgoing DWDM signal by a mutliplexer before being transmitted out of the switch. A wavelength-converting switch, connected across the switching matrices, is also included for switching channels between wavelengths. Thus, the switch provides port switching by virtue of the switching matrices and channel switching by virtue of the wavelength--converting switch, as well as a combination of both port and channel switching.
Patent CA-2288215-C (CA)
Inventor: HANSSON VIDAR
IPC: A61K31/711
Filed: 1998-04-29
Granted: 2009-08-18
Abstract: L'invention concerne l'utilisation de plusieurs composés capables d'inhiber la protéine kinase A (PKA) AMPc-dépendante afin de produire un médicament qui favorise la prolifération des lymphocytes T chez des patients atteints d'une maladie immunosuppressive. Parmi ces inhibiteurs, on trouve des analogues de l'AMPc, des ribozymes, de l'ADN antisens et des peptides se fixant sur la zone d'ancrage de la PKA.
Patent CA-2300517-C (CA)
Inventor: LARIVIERE YVES
IPC: B63C9/135
Filed: 2000-03-10
Granted: 2008-02-12
Abstract: A personal floatation device comprising: first means comprising at least a buoyant member provided with a neck receiving opening; and second means allowing to apply the weight of the wearer to said first means; wherein said second means are positioned underneath said first means to position the center of gravity of a combination "wearer - personal floatation device" substantially under the water level and prevent overturning of the same.
Patent CA-2301330-C (CA)
Title: Procede de controle de recipients munis de fermetures
Inventor: HEUFT BERNHARD
IPC: G01M3/36
Filed: 1998-08-25
Granted: 2007-07-03
Abstract: En vue de contrôler des caractéristiques de récipients (10) obturés par une fermeture (12), par exemple, siège central de fermeture (12) sur l'ouverture du récipient, résistance du siège de fermeture (12) ou volume d'air résiduel dans des récipients (10) où le liquide est amené à l'état moussant pour chasser le volume d'air résiduel avant fermeture, des vibrations mécaniques dans la fermeture (10) sont excitées et analysées. L'analyse des vibrations mécaniques s'effectue immédiatement après mise en place de la fermeture (12), avant que se produise une variation notable de pression dans le récipient.
Patent CA-2301703-C (CA)
Inventor: GEIGER PETER
IPC: B28B1/08
Filed: 1999-05-19
Granted: 2009-03-17
Abstract: The invention relates to a method for producing concrete stones, especially paving stones, building stones or such like, comprising a base part made of coarse- grained concrete (6) and a coloured facing layer made of concrete mortar which solidly covers the top of the base part. The coarse-grained concrete (6) is filled into a shaping tool (3) and compacted by vibrating and/or pressing in the shaping tool (3). From a storage reservo ir (5) coloured concrete mortar is deposited on the coarse-grained concrete in the sunk chamber of the shaping tool (3) and compacted. The invention aims to make it possible to obtain concrete mortar mixtures for preparing facing layers having a similar defined aspect. To this end the concrete mortar constituting the facing layer is formed of differently coloured layers (8, 9, 10, 11) which are stored in a stacked manner at the top of the reservoir (5). Th e concrete layers (8, 9, 10, 11) jointly and simultaneously are freely moved downwards by gravity together with partial sections and collide with or are guided onto an impact element (12) which is configured at a variable distance from the wall of the storage reservoir (5) and projects into the travel path of the partial sections. The partial sections are further guided by the impact element (12) along at least one deflection path and then mixed. As multicoloured concrete mortar they form, on the coarse-grained concrete, a marbled facing layer to be compacted.
Patent CA-2301932-C (CA)
Inventor: MANNIS MICHAEL L
IPC: F16K15/03
Filed: 2000-03-21
Granted: 2003-08-12
Abstract: A one-way spring tensioned flapper is located at one end of a valve housing to control the direction of flow. A rotatable plug at a second end can be partially opened to control the flow rate through the valve. A top mounted handle controls movement of the rotatable plug 90° in either direction from a longitudinal line between a first and second opening to the valve. A rubber seal on each side of the flapper and the rotatable plug prevents leakage in the closed position.
Patent CA-2307842-C (CA)
Inventor: WEIGEL PAUL H
IPC: C12P19/26
Filed: 1998-10-30
Granted: 2010-10-19
Abstract: The present invention relates to a nucleic acid segment having a coding region segment encoding enzymatically active Streptococcus equisimilis hyaluronate synthase (seHAS), and to the use of this nucleic acid segment in the preparation of recombinant cells which produce hyaluronate synthase and its hyaluronic acid product. Hyaluronate is also known as hyaluronic acid or hyaluronan.
Patent CA-2308968-C (CA)
Title: Mapping arbitrary signals into sonet
Inventor: ROBERTS KIM B
IPC: H04J3/16
Filed: 2000-05-18
Granted: 2010-01-26
Abstract: A synchronizer/de-synchronizer maps continuous format signals of an arbitrary rate into frames of pre-selected single common rate, such as SONET frames, with no bits changed and very little jitter or wander added. In this way, the continuous format signal may be carried transparently as a tributary of a SONET network. Each frame comprises a definite number of fixed stuff bits, including transport overhead bits and reminder fixed stuff bits. A frame also comprises an adjustable number of adaptive stuff bits, resulting from the phase difference between the arbitrary rate and the common rate. A mapping function is performed in a tributary unit shelf of a SONET transport shelf, and the reverse mapping function is performed in a similar way at the far end of a SONET connection. The stuff bits are spread uniformly within the frame.
Patent CA-2310104-C (CA)
Inventor: SCHILLING DONALD L
IPC: H04B1/707
Filed: 1991-11-14
Granted: 2003-07-15
Abstract: An apparatus for adaptive-power control of a spread-spectrum transmitter of a mobile station operating in a cellular-communications network using spread-spectrum modulation. A base station transmits a generic spread-spectrum signal and an APC information-data signal. A mobile station has an acquisition circuit (101, 102, 103) for acquiring and decoding the generic spread-spectrum signal, a detector (104) for detecting a received power level of the generic spread-spectrum signal, a decoder (105) decoding the APC-data signal as a threshold, a differential amplifier (106) for generating a comparison signal by comparing the received power level to the threshold, a transmitter (112) for transmitting a transmitter spread-spectrum signal, an antenna, and a variable-gain device (111) responsive to the comparison signal indicating an increase or decrease for adjusting a transmitter-power level of the transmitter spread-spectrum signal.
Patent CA-2310746-C (CA)
Title: Procede et dispositif de detoxification et de desodorisation de gaz de sterilisation
Inventor: KIRIHARA CHIKAO
IPC: B01D53/86
Filed: 1999-06-03
Granted: 2007-05-22
Abstract: La présente invention concerne un dispositif de détoxification et de désodorisation d'un gaz de stérilisation, comprenant une conduite principale dont la première extrémité fonctionne comme une admission de gaz de stérilisation et la seconde comme une sortie de gaz traité, un souffleur relié au côté d'admission au centre de la conduite principale, un préchauffeur, un élément d'oxydation/décomposition et un élément de refroidissement reliés en série depuis le souffleur vers la sortie, une conduite de dérivation raccordée pour le segment de la conduite principale où les dispositifs commençant par le souffleur et comprenant l'élément de refroidissement sont montés, est reliée à un réservoir de stérilisation. En outre, un dispositif de stérilisation est enclenché pour effectuer la stérilisation pendant une durée déterminée, le dispositif de détoxification et de stérilisation du gaz de stérilisation est enclenché peu avant la fin du processus de stérilisation pour faire circuler le gaz au ralenti, pendant une durée déterminée, entre les conduites principale et de dérivation, le gaz étant ensuite circulé entre le réservoir de stérilisation et la conduite principale pour être détoxifié. Enfin, on introduit un neutralisant dans le réservoir de stérilisation en vue d'un traitement ultérieur, consistant à répéter les mêmes étapes que lors du traitement du stérilisateur.
Patent CA-2314196-C (CA)
Inventor: YASUNORI SOUGAWA
IPC: C10M173/02
Filed: 2000-07-21
Granted: 2009-10-06
Abstract: The present invention provides for a lubricant oil composition for internal combustion engines, that resists oxidation in the presence of NOx and evaporation characteristics, and controls poisoning of a three-way catalyst system for occluding/reducing NOx and formation of deposit in an air intake system. The lubricant oil composition for internal combustion engines, comprises a base oil, which contains aromatic compounds at 1 wt.% or less, sulfur at 10 ppm or less, and paraffin and monocyclic naphthene compounds at 50 wt.% or more as total content, and has a kinematic viscosity of 2 to 50 mm2/s at 100°C and evaporated quantity of 16 wt.% or less determined by the NOACK  evaporation test, wherein the base oil is incorporated with a zinc dithiophosphate at 0.04 to 0.10 wt.% as phosphorus, a calcium phenate and/or calcium sulfonate having a total basic number of 100 to 400 mg KOH/g at 1 to 10 wt.%, and a polyalkenyl succinimide having a boron/nitrogen wt. ratio of 0 to 1.2 and alkenyl group of 1,000 to 3,500 in molecular weight at 0.01 to 0.20 wt.% as nitrogen.
Patent CA-2314593-C (CA)
Inventor: CHIANG HERMAN
IPC: A61F9/02
Filed: 2000-07-26
Granted: 2004-02-10
Abstract: The invention provides a new type of swimming goggles, characterized in that: a binding frame is used for assembling the main lens frames. The binding frame includes left and right frame units and a nose bridge that combines the left and right frame units. On the left and right frame units near the nose bridge is at least one clasp unit. On the main frame unit corresponding to the clasp unit is a clasp piece.  On one side of the left and right frame units away from the nose bridge is an assembling device, thus with the coordinative assembly of the clasp unit, clasp piece and the assembling device, the main frame unit can be securely fastened onto the binding frame.
Patent CA-2319531-C (CA)
Title: Low viscosity lube basestock
Inventor: CODY IAN ALFRED
IPC: C10G61/04
Filed: 1999-02-12
Granted: 2009-07-14
Abstract: The present invention is directed to an easily biodegradable low viscosity, low Noack volatility lube oil material having a viscosity index (VI) in the range of about 110-145, > 98 % saturates useful as lube oil basestock, automatic transmission fluid (ATF) basestock or blending stock. The lube oil material is produced by the isomerization of a wax feed having a viscosity of from 4 to 10 cSt at 100 °C and containing less than about 25 % oil in wax.