baber/WOPTO huggingface dataset:
Patent EP-4275751-A2 (EP)
Title: Improved naglu fusion protein formulation
Inventor: MOSHASHAEE SAEED
IPC: A61P25/28
Filed: 2017-02-24
Abstract: The present disclosure relates in general to therapeutic lysosomal enzyme fusion proteins useful for treating lyso-somal storage diseases, liquid formulations comprising such fusion proteins and associated methods useful for treating lysosomal storage diseases in mammals.
Patent EP-4306169-A2 (EP)
Title: Means and methods for generation of breast stem cells
Inventor: SCHEEL CHRISTINA H
IPC: A61P35/00
Filed: 2016-04-28
Abstract: The present invention is in the field of stem cell biology, in particular in the field of developmental and regenerative biology. The invention generally relates to a method of generating cells capable of differentiating to a multicellular organoid unit that morphologically and/or functionally resembles the terminal ductal-lobular unit. More precisely, said cells are generated by dissociating mammary epithelial tissue, thereby gaining cells and culturing said cells in presence of a compound which elevates cAMP levels in a collagen gel. Under said culturing conditions said cells form a multicellular organoid unit facilitating to obtain a breast stem cell by isolating a single cell from said multicellular organoid unit. The present invention also relates to enriching said cells and differentiating them to a multicellular organoid that morphologically and/or functionally resembles the terminal ductal-lobular unit and use of said cells or said multicellular organoid in testing a compound. Furthermore, the present invention relates to a composition comprising said breast stem cells or the multicellular organoid.
Patent EP-4254209-A2 (EP)
Inventor: HARRIMAN DAVID J
IPC: G06F13/38
Filed: 2013-10-30
Abstract: In an embodiment, an apparatus includes a counter to count between a start value and an end value according to a local clock signal, a first register to store an output of the counter, a mirror elastic buffer to store samples of the counter output received from the first register, where the mirror elastic buffer is to mirror an elastic buffer of a receiver circuit, and a resolution logic to receive a counter output sample from the mirror elastic buffer and a current counter value output from the counter, and to determine a transit latency for a data element to traverse the receiver circuit based at least in part on the counter output sample and the current counter value. Other embodiments are described and claimed.
Patent EP-4279728-A2 (EP)
Title: System and method for cold operation nox burden reduction
Inventor: KODAVASAL JANARDHAN
IPC: F02D41/00
Filed: 2021-12-07
Abstract: A method comprises determining that an aftertreatment system is in a cold-operation mode; initiating a low engine-out NOx (LEON) mode by controlling a component of a vehicle containing the aftertreatment system to decrease an instantaneous engine out NOx (EONOx) amount and to increase exhaust energy relative to a normal operation mode for an engine of the vehicle; receiving information indicative of an operating status of the vehicle during the LEON mode; disengaging the LEON mode; subsequent to disengaging the LEON mode, initiating a thermal management (TM) mode for the aftertreatment system, wherein the TM mode is initiated by controlling a component of the vehicle to increase fueling to the engine for a power level by reducing engine efficiency and directing excess fuel to the aftertreatment system; receiving information indicative of an operating status of the vehicle during the TM mode; and disengaging the TM mode.
Patent EP-4293099-A2 (EP)
Title: Loss reduction in beverage loading and unloading of water removal systems
Inventor: MCGOVERN RONAN
IPC: C12H3/04
Filed: 2018-12-07
Abstract: A method for reducing beverage loss during loading of beverage into an ethanol concentration system having a set of reverse osmosis pressure vessels, each pressure vessel having a feed inlet, a retentate outlet, and a permeate outlet. The method includes feeding deaerated water into the feed inlet of a first pressure vessel, feeding the beverage into the feed inlet of the first pressure vessel, monitoring an alcohol percentage at the retentate outlet of a second pressure vessel, the second pressure vessel coupled directly or indirectly to the first pressure vessel, and coupling a retentate from the retentate outlet of the second pressure vessel to a feed tank coupled to the feed inlet of the first pressure vessel when the alcohol percentage is within a first target range of 0.5 to 18% alcohol-by-volume (ABV).
Patent EP-4296720-A2 (EP)
Inventor: RAJAGOPAL ADITYA
IPC: G01S15/89
Filed: 2017-08-16
Abstract: An enhanced stethoscope device and method for operating the enhanced stethoscope are provided. The enhanced stethoscope device generally operates by providing stethoscope sensors, ultrasonic sensors, and other sensors to obtain a series of measurements about a subject. The series of measurements may be correlated, such as by machine learning, to extract clinically relevant information. Also described are systems and methods for ultrasonic beamsteering by interference of an audio signal with an ultrasonic signal.
Patent EP-4311204-A2 (EP)
Inventor: SHRIBMAN DERRY
IPC: H04L67/567
Filed: 2018-08-16
Abstract: A method for fetching a content from a web server to a client device is disclosed, using tunnel devices serving as intermediate devices. The tunnel device is selected based on an attribute, such as IP Geolocation. A tunnel bank server stores a list of available tunnels that may be used, associated with values of various attribute types. The tunnel devices initiate communication with the tunnel bank server, and stays connected to it, for allowing a communication session initiated by the tunnel bank server. Upon receiving a request from a client to a content and for specific attribute types and values, a tunnel is selected by the tunnel bank server, and is used as a tunnel for retrieving the required content from the web server, using standard protocol such as SOCKS, Web Socket or HTTP Proxy. The client only communicates with a super proxy server that manages the content fetching scheme.
Patent EP-0003914-A2 (EP)
Inventor: ASH STEPHEN RICHARD
IPC: A61K33/06
Filed: 1979-02-26
Abstract: A dialysis composition for adsorption of uremic substances in an artificial kidney is described, comprising a cation exchanger suspended in a suspending agent, A more particular example of such a composition comprises a surface adsorptive agent capable of adsorption of uremic substances; an enzyme to serve as a catalyst for urea degradation; a suspending agent; and a cation exchanger capable of being suspended in said suspending agent. A method for removing uremic substances from blood during hemodialysis with the above dialysis compositions is also described.
Patent EP-0003465-A2 (EP)
Inventor: LE COENT FERNAND
IPC: E06B3/30
Filed: 1979-01-29
Abstract: 1. Composite section for building joineries such as doors and windows, made-up of a metal core (1) linked to an exterior plastic cover by a sealing product (4) located between the exterior of the core (1) and the interior of the cover (3), characterized by metal core (1) has first means for mechanical link-up (15), exterior cover (3) comprises a second set of apparatus for mechanical link-up, (16), the first and second means of mechanical link-up of the core (1) and the cover (3) are connected mechanically in longitudinal fashion, the sealing product is one possessing a softening-up temperature greater than the plastic material making up the outside cover (3).
Patent EP-0006809-A2 (EP)
Inventor: CACCIUTTOLO PASCAL CHARLES
IPC: E01C11/04
Filed: 1979-06-22
Abstract: The machine comprises at its front a pouring apparatus 11 for the foundation concrete 12, a chute 13 for guiding the plastic joint member 2 in the thickness of the concrete, and, at its rear, a chute 16 for the distribution of the concrete 15 of the surfacing course 8, in front of which a mechanism 17 for laying the transverse joint members 3 can slide, the speed of which mechanism is synchronised with the speed of advance of the machine so that the joint member is immobile during the laying, the latter then being wholly embedded under the surfacing course. This machine is applied for motorway working and for various concrete-surface works. <IMAGE>
Patent EP-0019883-A2 (EP)
Inventor: KOMATSU SHIGERU
IPC: H01L29/41
Filed: 1980-05-23
Abstract: A semiconductor device, wherein an alloy wire (33) is mounted on the surface of a semiconductor substrate (31) carrying semiconductor element with a first densely formed electric insulation layer (32) interposed between said alloy wire and semiconductor substrate surface: after forming a second insulation layer (34) in the prescribed positions, a pure aluminium electrode (35) is deposited, one part of which is connected to said alloy wire (33) and the other part of which is attached to said first densely formed electric insulation layer (32), thereby constituting a wire bonding pad; and finally heat treatment is carried out to effect an ohmic contact between the aluminium electrode (35) and the alloy wire (33).
Patent EP-0030642-A2 (EP)
Inventor: AVIRAM ARI
IPC: B41C1/00
Filed: 1980-11-20
Abstract: An improved lithographic printing plate includes a substrate layer (2) of a nonconducting, hydrophobic material, an intermediate film (3) of conducting, hydrophilic material such as aluminum and a top protective film (5) of relatively hard hydrophilic dielectric material, such as aluminum oxide. A printing image is formed in the lithographic printing plate by an electroerosion process wherein erosion electrodes (7) are pulsed with voltage to break down the dielectric film (5) in areas adjacent to the erosion electrodes (7) and to evaporate or otherwise remove corresponding portions of the conducting film (3), thereby creating holes (8) that extend through the dielectric (5) and conducting (3) films and that expose portions of the surface of the underlying hydrophobic substrate (2).
Patent EP-0030735-A2 (EP)
Inventor: THORELL JAN I
IPC: G01N33/543
Filed: 1980-12-16
Abstract: 1. Shielding agents intented to be used as reagents in radioimmuno-assays in which shielding takes place in the sample itself, characterized in that the individual particles present a size from 1 to 100 mu m and consist of a first active component and a second active component in combination with a support matrix, the particle size and particle density being so adjusted to each other that the particles present a sedimentation rate amounting to 1-180 minutes, and each of these particles contains as first active component a shielding agent having a high capacity for absorption of the radiation emitted from a radioligand of a radioimmuno-assay and as second active component a material which acts on the reagent of the reaction product of said radioimmuno-assay.
Patent EP-0044967-A2 (EP)
Inventor: BLANC GUY-FRANCOIS DIPL-ING
IPC: G05B19/23
Filed: 1981-07-04
Abstract: A position-control system for a positioning cylinder drive having a P-characteristic controller (9) compensates for a remaining control deviation or error arising in a positioning process. A correcting signal is produced from the output of a reference position value/actual position value subtraction unit (7), either while the positioning drive has stopped or when, during the positioning process, the subtraction unit output passes through a zero point. Said correcting signal is held in a store, (13) and from there transmitted to the subtraction unit to actuate a compensating movement of the drive. As a discrete value has to be transmitted only once in the control circuit, problems of instability or unsteadiness in the compensating process are avoided. <IMAGE>
Patent EP-0057246-A2 (EP)
Inventor: NEUHIERL HERMANN DR
IPC: A63H18/12
Filed: 1981-09-14
Abstract: 1. Toy car racing track, consisting of at least one vehicle and track sections that can be put together in sequence with at least one lane (R, L) with guide media (36, 37) and with power conductors (30 to 33) for the vehicle or vehicles, which can be brought into electrical contact with the power conductors via current collector sliders (2, 3), having a controllable steering device (12) over the power conductors (30 to 33) and the current collector slides (2, 3), and guide links, with which they can mutually engage wit the guide media (37), being guidable along the track sections (35), characterised by, each lane (R, L) of each track section (35) having as guide media both a guide groove (37) as well as a guide edge (36) over its complete length and that at least one of the vehicles has as the guide link a removable and reinsertable guide stud (11) for engagement in the guide groove (37), so that it can be used, as required, as a steerable vehicle without guide stud (11) or as a lane bound vehicle with guide stud (11).
Patent EP-0064601-A2 (EP)
Inventor: KREYLOS HANS-ALBERT
IPC: A61C13/00
Filed: 1982-04-05
Abstract: Die Erfindung betrifft ein Verfahren zur Herstellung von Zahnersatzteilen, bei denen ein metallisches Sekundärteil abnehmbar über Halteelemente an einem ebenfalls metallischen, festsitzenden Primärteil verankert ist. Als Halteelemente dienen Riegel oder Friktionsstifte, für die entsprechende Aufnahmen mit genauer Passung im Primär und Sekundärteil geschaffen werden müssen. Bisher hat man diese Aufnahmen im Primärteil gebohrt oder gefräst. Die Aufnahme für das Halteelement im Sekundärteil wurde beim Gießen geformt. Dieses Verfahren gewährleistet keine genaue Passung und ist bei edelmetallfreien Legierungen nicht anwendbar. Gemäß der vorliegenden Erfindung werden die Aufnahmen nun durch Funkenerosion geschaffen. Damit wird eine einwandfreie Passung zwischen dem Halteelement und der Aufnahme auch bei Zahnersatzteilen aus einer edelmetallfreien Legierung erreicht.
Patent EP-0068118-A2 (EP)
Inventor: SENOO YASUTAKA
IPC: H01H13/00
Filed: 1982-05-07
Abstract: A switch comprises a movable conductive contact (5) in the form of a curved plate having an arcuate cross section. and terminals (1a, 1b) having ends (2a, 2b) projecting into a cavity. The movable conductive contact is pressed into the cavity to cause an end of the contact to be resiliently held against and slidably supported on the ends of the terminals.
Patent EP-0077096-A2 (EP)
Inventor: BELL JAMES PAUL
IPC: C08L33/02
Filed: 1982-10-04
Abstract: The invention provides curable compositions comprising (1) 100 part by weight of an epoxy compound containing at least one vicinal epoxy group, (2) from 1 to 25 parts by weight of a saturated poly(alkyl acrylate) having a molecular weight of less than 10,000 and a carboxyl functionality greater than 1.15 and (3) a curing amount of an epoxy curing agent, which compositions may be cured by application of heat. 
     The composition may be used as adhesives, surface coatings, in preparing laminates, in castings, and in encapsulation of electrical equipment.
Patent EP-0079121-A2 (EP)
Inventor: WAAS FRANK FERDINAND GEORG MIC
IPC: H05K3/00
Filed: 1982-09-29
Abstract: Apparatus for conveying flat, preferably plate-shaped members (9) that have previously been processed on one or both surfaces through a processing unit (8), for example, conveying printed electrical circuit boards through a circulating air drying or auxiliary finishing oven, includes a rotor (10) having more than one receptor device (13) for accepting the members (9) individually. which receptor devices are situated on the periphery of a hub-shaped carrier (12). The rotor is driven to rotate in a stepwise fashion corresponding to the arrangement of the receptor devices. Means (19) for loading and unloading the members, that function within the periphery of the rotor are also provided.
Patent EP-0085250-A2 (EP)
Inventor: LEHRER ROBERT I
IPC: C07K14/47
Filed: 1982-12-21
Abstract: Novel microbicidal compositions are provided which find use as preservatives, disinfectants, antigens and the like. Particularly, cationic oligopeptides of up to about thirty-five amino acids are provided having amino acid sequences substantially comparable to the amino acid sequences of cationic oligopeptides produced by macrophage. A conserved framework structure is provided.
Patent EP-0083867-A2 (EP)
Inventor: OJIKA YOSHIHIKO
IPC: C09D1/02
Filed: 1982-12-23
Abstract: n inorganic undercoating paint composed essentially of a water-soluble alkali metal silicate or a modified product thereof, or a mixture thereof, and a relatively large quantity of a curing agent is applied to an inorganic base to form an undercoating thereon. The undercoating is treated with an acid, and dried, whereby a multiplicity of fine cracks are formed in the undercoating. An inorganic finish coating paint is applied in a thin film onto the undercoating. The finish coating paint is composed essentially of a water-soluble alkali metal silicate or a modified product thereof, or a mixture thereof, and a relatively small quantity of a curing agent.
Patent EP-0057141-A2 (EP)
Inventor: COUSSE HENRI
IPC: C07C67/14
Filed: 1982-01-21
Abstract: 1. As novel chemical compounds, the halobiphenylcarboxylate esters of the general formula (I)  see diagramm : EP0057141,P10,F1  in which X represents a halogen in the 2'- or 3'-position, R represents a straight-chain or branched alkyl containing from 1 to 16 carbon atoms, a cycloalkyl, a benzyl, an aminoalkyl or a pyridylalkyl, and the salts with therapeutically acceptable mineral or organic acids when R represents an aminoalkyl group or a pyridylalkyl group.
Patent EP-0060803-A2 (EP)
Inventor: RIEGER HANSJORG DR-ING
IPC: B60C27/06
Filed: 1982-03-12
Abstract: 1. Anti-skid tyre chain with a retainer (1, 3) on each side coming into contact with the inside and the outside of the tyre when the chain is fitted, for chain strand sections extending over the tread and mounted rotatably at the inner retainer, with which a tensioning strand (8) serves for tensioning the inner retainer (1), which is formed by a resilient steel bow and can be draped over the tyre, which tensioning strand bridges a space between the ends of the inner retainer (1) and the free end of which is led over the tread of the tyre to the outer retainer (3) after returning back on itself at least once, the inner retainer (1) having, at its end, swivel pins (14, 15) for rotatable connecting pieces (4, 5) for the tensioning strand (8) and/or connecting parts (6, 7) connecting said tensioning strand to the connecting pieces (4, 5) and movements about the swivel pins (14, 15) being introduceable through end members (18, 19) of chain strand sections (20, 21) of the tread network (2) into the connecting pieces (4, 5) of which at least one (5) is provided with a return pin (9) or a return pulley for the tensioning strand (8), characterized in that the connecting pieces (4, 5) have basic elements designed as punched parts in each case with a web (23) and in that in each case an end member (19) of a chain strand section (20, 21) of the tread network is mounted to rotate through 360 degrees on a swivel pin (14, 15) in the direct vicinity of one end in each case of the inner retainer (1) together with the web (23).
Patent EP-0090925-A2 (EP)
Inventor: WEILNHAMMER AUGUST
IPC: B60B30/06
Filed: 1983-02-08
Abstract: 1. A device for fitting solid tyres to rims or respectively dismantling them therefrom, more especially having rim taper-, sidewall and closure rings (14, 15) as detachable parts, in which respect, centrically adapted to the diameter of the rim (10) and acting against one another, are provided a mounting (8) for the rim as well as abutments for the axial pressing of the solid tyre, characterised by the use of the following measures, that (a) a stationarily horizontally arranged flat steel plate (2) with an opening (11) exceeding the outside diameter of the lateral sidewall ring (15) of the rim (10) is provided as abutment, which has reinforcing ribs (12, 12') at location of maximum bending load, and (b) the mounting (8) for the rim (10) is arranged on a vertically acting lifting unit (1).
Patent EP-0090268-A2 (EP)
Inventor: BIRKLE SIEGFRIED DR
IPC: C25D11/08
Filed: 1983-03-16
Abstract: Aluminum materials and aluminized parts are oxidatively anodized at a bath temperature of 0 DEG  to 15 DEG  C. and preferably, 0 DEG  to 10 DEG  C. to produce an anodized layer of aluminum oxide more than 4 microns thick, which is hard, abrasion-proof and can be stained. The anodizing is bath used while conducting air free of or low in carbon dioxide through the bath. It is free of substances which limit the oxide layer to maximally a thickness of about 1 micron (forming layer) and contains 10 to 500 g trisodium phosphate or tripotassium phosphate per liter. In partially aluminized parts, no destruction of the base material occurs during the aluminizing.
Patent EP-0094104-A2 (EP)
Inventor: KAJIWARA TOSHIYUKI
IPC: B21B37/42
Filed: 1980-09-29
Abstract: A rolling mill having a pair of intermediate rolls (13, 14) interposed between a pair of working rolls (1, 2) and a pair of backing rolls (28, 29) so that the intermediate rolls (13, 14) are axially displaceable in conformity with the width of a rolled material (3) and the intermediate rolls having bending means (19 to 22) and guiding members (17) so that the shape of the sheet (3) is controlled by adjusting the axial position of the intermediate rolls (13,14) and by exerting bending forces to the intermediate rolls.
Patent EP-0103901-A2 (EP)
Inventor: ARAI FUMINORI
IPC: C12Q1/28
Filed: 1983-09-21
Abstract: A multilayer analytical element comprising a water-impermeable, light-transmissive support, a reagent layer containing a color forming reagent composition for detection of hydrogen peroxide including at least combination of a chromogen and a coupler (a color indicator composition), and peroxidase, which produces a detectable change in the presence of peroxidase and hydrogen peroxide, and a porous spreading layer, which are superposed in this order, in which said chromogen is a 1,2,3,-tri-substituted compound of 4-amino-3-pyrazoiin-5-one having solubility in water at 25°C of lower than that of 4-amino-2, 3-dimethyl-1-phenyl-3-pyrazolin-5-one.
Patent EP-0143121-A2 (EP)
Inventor: KOLESKE JOSEPH VICTOR
IPC: C09D175/04
Filed: 1983-12-01
Abstract: This invention is directed to adducts of a polycaprolactone polyol and a polyepoxide comprising the reaction product of at least one Polycaprolactone polyol and a polyepoxide containing two or more epoxy groups per molecule in a molar ratio of polycaprolactone polyol to polyepoxide of from about 2:1 to about 3:1, said adducts having an oxirane content of less than about 0.10 percent and a viscosity of less than about 3700 centistokes at 54.5°C. The adducts are useful in the formulation of high solids coating compositions, polyurethane elastomers, inks, sealants, adhesives and the like.
Patent EP-0086018-A2 (EP)
Inventor: GIROLDINI VILLIAM
IPC: C07C239/00
Filed: 1983-01-27
Abstract: Process for the preparation of esters of carbamic acids by carbonyiation of aromatic nitrocompounds, with carbon monoxide, in the presence of alcohols and of catalyst consisting of metallic selenides.
Patent EP-0104711-A2 (EP)
Inventor: BRONNES ROBERT LEWIS
IPC: B23K35/00
Filed: 1983-09-26
Abstract: Beryllium to metal seals are produced by forming on a beryllium surface by cathode sputtering a first metal layer from a group of metals including tantalum, niobium, zirconium, hafnium, titanium or vanadium, an intermediate cathode sputtered layer of a refractory metal and outer layer of a readily brazable metal and soldering the readily brazable layer to another metallic body.