baber/WOPTO huggingface dataset:
Patent CA-2583967-A1 (CA)
Inventor: GRANDEL ROLAN
IPC: C07D333/34
Filed: 2005-10-14
Abstract: The present invention relates to 6-amino(aza)indane compound of the formula (I) Wherein Ar is phenyl or an aromatic 5- or 6-membered C-bound heteroaromatic radical, wherein Ar may carry 1 radical Ra and wherein Ar may also carry I or 2 radicals Rb; X is N or CH; E is CR6R7 or NR 3; R1 is C1-C4-alkyl, C3-C4-cycloalkyl, C3-C4-cycloalkylmethyl, C3-C4-alkenyl, fluorinated C1-C4-alkyl, fluorinated C3-C4-cycloalkyl, fluorinated C3-C4-cycloalkylmethyl, fluorinated C3-C4-alkenyl, formyl or C1-C3-alkylcarbonyl; R1a is H or R1a and R2 or R1a and R2a together are (CH2)n with n being 1, 2, 3 or 4; R2 and R2a each independently are H, CH3, CH2F, CHF2 or CF3; R3 is H or C,-C4-alkyl; and the physiologically tolerated acid addition salts of these compounds. The invention also relates to pharmaceutical compositions comprising at least one compound of the formula (I) or a pharmaceutically acceptable salt thereof and to a method for treating a medical disorder susceptible to treatment with a dopamine D3 receptor ligand, said method comprising administering an effective amount of at least one compound of the formula (I) or a pharmaceutically acceptable salt thereof.
Patent CA-2587556-A1 (CA)
Title: Dental fillers including a phosphorus containing surface treatment, and compositions and methods thereof
Inventor: MITRA SUMITA B
IPC: A61K6/838
Filed: 2005-11-07
Abstract: The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes phosphorus and a divalent cation. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment.
Patent CA-2588447-A1 (CA)
Title: Multiwell sample plate with integrated impedance electrodes and connection scheme
Inventor: SUGARMAN JEFFREY H
IPC: B01L3/00
Filed: 2006-03-24
Abstract: As disclosed within, the present device is directed to a multi-well sample module having integrated impedance measuring electrodes (which allow for the generation of an electric field within each well and the measuring of the change in impedance of each of the well's contents) and an electrical connection scheme allowing simultaneous measurement of each well's change in impedance.
Patent CA-2589974-A1 (CA)
Inventor: SZOKE BELA BILL
IPC: F16B7/04
Filed: 2007-06-07
Abstract: Mechanical lap splicing enclose two reinforcing bars by metal rings (1 and 4) at their overlapping part, or in their full length keeping them in parallel position, and ensuring that the minimum tensile strength will equal to one reinforcing bar's cross sectional area, rather than employing various mechanical splices with different tensile strength and requiring more qualified tradesperson to produce and assemble them, and the shortage of qualified tradesman will continue in the future. Lap splicing is the most economical, although individual connection by tie wire is none uniform connection. Mechanical lap splicing is quick, superior to tie wire connections, because it is uniform, especially in vertical bars connection where tie wire connection is difficult and time consuming.
Patent CA-2593697-A1 (CA)
Title: Pan-her antagonists and methods of use
Inventor: MONTICELLO DANIEL J
IPC: A61P35/00
Filed: 2005-06-30
Abstract: The present invention features human epidermal receptor (HER) antagonists.  These antagonists are polypeptide variants of ligands of HER. The HER ligand polypeptide variants of the invention possess Pan-HER antagonistic properties and can inhibit at least one HER-mediated biological activity of one or more HER subtypes, such as inhibition of the receptor's kinase activation activity and subsequently, cell proliferation. Such polypeptide variants, and nucleic acids encoding these polypeptide variants can be used therapeutically in situations in which inhibition of HER activity is indicated.
Patent CA-2594862-A1 (CA)
Title: Use of a combination of substances to prevent biofouling organisms
Inventor: MARTENSSON LENA
IPC: A01P15/00
Filed: 2006-01-27
Abstract: This invention relates to the use of a combination of selected substances in paint to prevent the settlement and growth of different biofouling organisms with a reduced negative effect on the ecosystems compared to present methods.
Patent CA-2602545-A1 (CA)
Inventor: KROMOVA TATYANA ALEXANDROVNA
IPC: A61P29/00
Filed: 2006-03-24
Abstract: The present invention relates to novel phenyl-N-acyl derivatives of biogenic amines and amino acids of general formula (I) ( see formula I) as cyclooxynease inhibitors, possessing analgetic and anti-inflammatory properties and devoid of side effects in particular ulcerogeneity and pro-spasmodic actions, as well as capability to potentiate effect of other analgetics, and possessing in addition antihypoxic, antidepressant and anti-Parkinsonistic action; as well as to the processes for the preparation novel and known phenyl-N-acyl derivatives of biogenic amines, to a pharmaceutical composition and to an agent comprising compounds of general formula (I) as well as to use thereof and a method of treating.
Patent CA-2604939-A1 (CA)
Title: Clash-free irregular-repeat-accumulate code
Inventor: GRAY PAUL KINGSLEY
IPC: H03M13/11
Filed: 2006-04-14
Abstract: Methods, apparatuses, and systems are presented for performing data encoding involving receiving a sequence of data bits, encoding the sequence of data bits in accordance with a parity check matrix (H-matrix) to generate a sequence of encoded bits, wherein the H-matrix is capable of being partitioned into a first matrix and a second matrix, the first matrix being a dual-diagonal matrix, the second matrix comprising one or more vertically stacked sub-matrices, each sub-matrix consisting of a plurality of columns, each column having a column weight of no more than 1, wherein the second matrix is capable of being expressed as a product of a parity check matrix, an interleaver permutation matrix, and a repeat block matrix, and the interleaver permutation matrix satisfies a clash-free interleaver constraint, and outputting the sequence of encoded bits.
Patent CA-2605054-A1 (CA)
Title: Construction safety system
Inventor: HATFIELD JAMES ROBERT
IPC: E04G21/32
Filed: 1997-08-12
Abstract: A fall arrest system. The mount dismounting bracket is a designed system to protect a person during a fall from a roof falling from a distance greater than 3 metres (10 feet) that will cause injury or death in new construction or renovation construction in residential and commercial construction sector where a fall protection is required.
Patent CA-2606553-A1 (CA)
Inventor: KENDRICK RICHARD D
IPC: B32B5/16
Filed: 1998-01-05
Abstract: One or more particulate active agents are fused to the surface of a substrate web by mixing the particulate agents with a particulate binder having a particle size not exceeding an average diameter of approximately 40 microns and coating the composite mixture onto the surface of the substrate. Thereafter, the coated substrate is heated to a temperature equal to or greater than the Vicat softening temperature of the binder and compressed within the nip of a pair of pressure rolls to achieve fusion. If desired, a top layer may be placed upon the coated composite prior to the compression step. Also disclosed are various products manufactured by the process.
Patent CA-2608149-A1 (CA)
Title: Capability assessment of a training program
Inventor: DOUBET BARTON L
IPC: G05B19/418
Filed: 2006-05-09
Abstract: Methods and apparatuses for profiling and modifying the training program of a company. Characteristics of the training program are aligned to a set of training supply chain components (301, 303, 305, 307, 309, 311) of a capability assessment model. The components are assessed and reported to show a comparison of the company with the leader in the associated business segment by categorizing the components (201, 203, 205, 207). An assessment report (500) is displayed that includes indicia (501-511) indicative of a comparison of the company's training program with the business segment leader for each component of the training program model. The indicia may further reflect a degree of difference between the training program of the company and the business segment leader. Training characteristics (401-447) associated with at least one component of a training program may be recommended from the assessment results to change the categorization of the at least one component.
Patent CA-2610261-A1 (CA)
Inventor: EHLERS GREGORY ALLEN
IPC: F26B3/06
Filed: 2007-11-13
Abstract: A dryer for drying moist goods is provided. The dryer reduces the amount of conditioned air used during the drying cycle by drawing drying air from the exterior of the building rather than the interior of the building thereby reducing the overall energy efficiency of the building. The dryer includes an air flow passage extending between a fresh air inlet and an exhaust air outlet. A drying chamber forms a portion of the air flow passage and is interposed between the fresh air inlet and the exhaust air outlet. A blower moves air through the air flow passage. The fresh air inlet and exhaust air outlet are separated from one another by a common wall and are positioned adjacent to one another.  The fresh air inlet and exhaust air outlet are configured to attach to a combined supply and exhaust duct such that exhaust air and fresh air are passed between the dryer and the exterior of the building through the combined supply and exhaust duct.
Patent CA-2611378-A1 (CA)
Title: Aminoquinoline and aminoquinazoline kinase modulators
Inventor: GAUL MICHAEL DAVID
IPC: C07D401/14
Filed: 2006-06-07
Abstract: The invention is directed to aminoquinoline and aminoquinazoline compounds of Formula I: where R1, R2, R3, B, Z, Q, p, q and X are as defined herein, the use of such compounds as protein tyrosine kinase modulators, particularly inhibitors of FLT3 and/or TrkB, the use of such compounds to reduce or inhibit kinase activity of FLT3 and/or TrkB in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to FLT3 and/or TrkB. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as cancers and other cell proliferative disorders.
Patent CA-2611618-A1 (CA)
Inventor: MUSTEN PHILIP
IPC: B08B3/02
Filed: 2004-06-10
Abstract: Apparatus producing superheated water and/or steam for weed (36) killing, et c. has diesel fired boiler (30), which, via pump (32), generates hot water at a pressure of 40-52 bar and temperature of 90-115~ C. This passes down tube (1 2) and encounters the constriction provided by nozzle (14). Passing through nozzle (14) into depressurisation chamber (16), which is at atmospheric pressure, the water boils. When the super heated water exits ports (20) of distribution pipe (18) it encounters ambient temperature and is transformed into high temperature water vapour and/or water droplets. The apparatus controls or kill weeds (36) using a smaller volume of water and less energy.
Patent CA-2612585-A1 (CA)
Title: Anti-inflammatory aryl nitrile compounds
Inventor: DUQUETTE JASON A
IPC: A61K31/395
Filed: 2006-06-26
Abstract: Compounds, (I) compositions and methods that are useful in the treatment of inflammatory and immune conditions and diseases are provided herein. In particular, the invention provides aryl nitrile compounds which modulate the expression and/or function of a chemokine receptor. The subject methods are useful for the treatment of inflammatory and immunoregulatory disorders and diseases, such as multiple sclerosis, rheumatoid arthritis, type I diabetes, asthma, psoriasis and inflammatory bowel disease. All definitions are as given in claim 1.
Patent CA-2613654-A1 (CA)
Inventor: SLAGER ELISABETH HELENA
IPC: C07K14/475
Filed: 2006-06-29
Abstract: The invention identifies tumor-associated antigens that may be used for immunotherapy of malignancies in patients having undergone an allogeneic stem cell transplantation, whereby the therapy is mediated by induction of a graft versus tumor immune response. The invention discloses minor histocompatibility antigens encoded by polymorphisms in reading frames present in the hECGF-1 gene. The invention provides peptides comprising polymorphic minor histocompatibility binding peptides or fragments, which may be in the context of an MHC molecule. The invention also provides T cell receptors and T  lymphocytes capable of binding to these minor histocompatibility antigens, preferably in the context of MHC molecules. The molecules and cells of the invention can be used for treatment of subjects and manufacture of medicaments for the treatment of subjects suffering from malignancies expressing the hECGF-1 protein.
Patent CA-2614292-A1 (CA)
Inventor: PAZ ADRIAN
IPC: A61B17/064
Filed: 2006-07-06
Abstract: The invention provides a surgical fastener. The fastener has a first element defining an axis of the fastener, and or more prongs attached to the first element at hinge regions. Deploying the fastener involves bending the prongs at the hinges so as to increase the distance of the prong tips from the axis and locking the fastener in this deployed configuration. The invention also provides a surgical fastening device and a method for attaching a surgical fastener to a site of a body tissue.
Patent CA-2617952-A1 (CA)
Inventor: ROSSI MASSIMO
IPC: B29C45/28
Filed: 2006-08-02
Abstract: Injection system with closing rod (2) provided with a cleaning device (6, 7, 8) suitable for removing the powder of molten plastic that builds up in the movement areas of the closing rod (2) , in particular in the thrust bearing (3), during the normal operation of a molding machine. Advantageously the system according to the invention avoids the limitation of the piston stroke and the subsequent blockage with time and thus also the blockage of the closing rod, considerably reducing the number of maintenance operations and thus increasing the productivity of the molding machine.
Patent CA-2618302-A1 (CA)
Inventor: HIGGINS ROBERT SCOTT
IPC: A42B3/04
Filed: 2008-01-18
Abstract: A sports helmet having a pair of strap retainers affixed thereto is provided for use with goggles held on a wearer's head by a strap. One strap retainer is affixed on each side of the helmet at a height above the goggle strap when the goggles are over the eyes of the wearer. The strap retainers are formed with an inner arm affixed to the side of the helmet and an outer arm spaced therefrom. When the wearer moves the goggles upward from the eyes to rest on the front rim of the helmet, the strap slides along the helmet and is entrapped in each strap retainer to prevent the goggles from sliding over the top of the helmet to an inconvenient position.
Patent CA-2619327-A1 (CA)
Title: Mercaptan-hardened epoxy polymer compositions and processes for making and using same
Inventor: BYERS JIM D
IPC: C09J163/00
Filed: 2006-08-16
Abstract: Mercaptan-hardened epoxy polymer compositions, methods of making the mercaptan-hardened epoxy polymer compositions, and methods of using the mercaptan-hardened epoxy polymer compositions are provided. The mercaptan-hardened epoxy polymer can be produced by contacting a thiol ester composition and an epoxide composition to produce a mixture and then heating the mixture to produce the mercaptan-hardened epoxy polymer. In some embodiments, the thiol ester compositions include thiol esters, hydroxy thiol esters, and crosslinked thiol esters. Adhesive polymer compositions, methods of making the adhesive polymer compositions, and methods of using the adhesive polymer compositions are provided. The adhesive polymer composition can be produced by contacting a thiol ester composition and an epoxide composition to produce a mixture and then heating the mixture to produce the adhesive polymer composition.
Patent CA-2620632-A1 (CA)
Title: Flow formed spline and design suitable for burr free machining
Inventor: VASA BEN R
IPC: B21D22/00
Filed: 2006-08-31
Abstract: A method and tool (50) for forming a flow formed part (22) are disclosed, wherein the tool (50) has an annular array of spline forming recesses (58) for producing a flow formed part (22) having splines (24) and machining and production costs are minimized and efficiency is maximized.
Patent CA-2622969-A1 (CA)
Title: Thread spool and cap
Inventor: LYMAN JAMES
IPC: B65H49/18
Filed: 2006-09-06
Abstract: The present invention relates to thread storage and dispensing systems which protect the thread from damage. A spool system of the present invention includes a thread spool around which thread is wound. A spool cap is mounted to the thread spool in a manner which substantially encloses the thread. The spool cap may include an opening through which the thread is extended as it is fed into a sewing machine. The spool cap may be selectively and removably mounted to the thread spool in any of a variety of manners. For instance, detents may be provided on the cap to engage a corresponding groove in the thread spool. Optionally, a stopper is provided which may be inserted into the opening through which the thread is fed into a sewing machine. The stopper may frictionally engage the cap and thread, and secure the thread to prevent it from unraveling.
Patent CA-2623957-A1 (CA)
Inventor: SIPIONE SIMONETTA
IPC: A61K35/39
Filed: 2006-09-26
Abstract: The present invention is related to the discovery that serpina3n, a secreted protein, binds to and inhibits granzyme B activity. The invention thus provides cells that include a polynucleotide encoding a granzyme B inhibitory serpin, pharmaceutical compositions including a granzyme B inhibitory serpin or a polynucleotide encoding a granzyme B inhibitory serpin, methods for treating a patient in need of immunosuppression by administration of a granzyme B inhibitory serpin, and methods of transplanting cells (e.g., islet cells) expressing a granzyme B inhibitory serpin.
Patent CA-2624543-A1 (CA)
Inventor: DENIS LAURENT
IPC: F16B19/02
Filed: 2008-04-10
Abstract: A mounting for connecting an operating head that generates vibrations when in use to a vehicle in a manner to minimize the transmission of the vibrations from the head to the vehicle. The mounting includes a number of female connecting means on one of the head and the vehicle and a similar number of male connecting means on the other of the head and vehicle, the male connecting means each carrying a resilient sleeve. The male connecting means are inserted into the female connecting means and a bolt is passed through each female connecting means and each resilient sleeve associated with it to join the head to the vehicle.
Patent CA-2625749-A1 (CA)
Inventor: FIUMIDINISI ALESSANDRO
IPC: F24H1/18
Filed: 2006-10-12
Abstract: Disclosed is a hot water tank (10) comprising an outer container (14) and an inner container (12) that is disposed inside the outer container (14), is used for receiving hot water, and is located at a distance from the outer container (14). A heat insulation layer (26) is placed between the inner container (12) and the outer container (14). The inner container (12) is provided with planar polygonal walls (22a, 22b, 28, 28b) while the outer container (14) is provided with planar polygonal walls (24a, 24b, 30a, 30b). The inner container (12) and/or the outer container (14) are equipped with supporting elements (16) which are configured so as to counteract an internal pressure of the hot water tank (10) in order for the hot water tank (10) to maintain the shape thereof.
Patent CA-2628843-A1 (CA)
Inventor: BEREZIN VLADIMIR
IPC: C07K4/12
Filed: 2006-11-07
Abstract: The present invention relates to peptide sequences capable of stimulating neuronal cell differentiation, neural cell survival and neuronal plasticity associated with memory and learning. The peptide sequences of the invention are derived from the proteins belonging to neurotrophic factors, such as NGF, NT3, NT4/5 and BDNF. The invention also relates to pharmaceutical compositions comprising said peptide fragments and uses thereof for treatment of a disease or condition wherein the effects of stimulating neuronal cell differentiation, neuronal cell survival, stimulating neural plasticity associated with learning and memory are beneficial for treatment.
Patent CA-2630770-A1 (CA)
Inventor: SOMBOONTHUM PRANEE
IPC: C12N7/00
Filed: 2005-11-24
Abstract: Disclosed are recombinant varicella-zoster virus, a process for producing the virus, a pharmaceutical composition comprising the recombinant varicella-zoster virus, a vector having a BAC vector sequence in a specific gene of the varicella-zoster virus genomic gene, a cell having the vector therein, a fragment capable of homologous recombination with the varicella-zoster virus genome, a nucleic acid cassette comprising a BAC vector sequence, and a polyvalent vaccine. A process for producing a recombinant varicella-zoster virus having a BAC vector sequence inserted in a specific viral gene.
Patent CA-2631597-A1 (CA)
Title: Parent-child showerhead
Inventor: Qiu jia-sen
IPC: E03C1/04
Filed: 2008-05-20
Abstract: A parent-child showerhead includes a wall-mounted showerhead, a hand-held showerhead, and a showerhead bracket. The wall-mounted showerhead is fixed on a conduit extending from a wall and connects to the hand-held showerhead via a hose. The showerhead bracket is provided for the hand-held showerhead to hang thereon.  The wall-mounted showerhead has a water diverter disposed therein for controlling the spray water from the wall-mounted showerhead or the hand-held showerhead or from both of them. The water diverter has an adjusting knob for changing a direction of the water flow, and the adjusting knob is located on the wall-mounted showerhead at side close to a user, which is convenient for users to operate. The showerhead bracket is disposed at a lower position of the wall-mounted showerhead, and has a receptacle. The receptacle is in a pivoted state to adjust an angle and provide the hand-held showerhead to be engaged therein.
Patent CA-2636541-A1 (CA)
Inventor: AKIYOSHI KENJI
IPC: G09G5/00
Filed: 2008-06-30
Abstract: A vector image drawer comprises: an outline definer, a divider, an outline flag setter, a filler, and a continue flag setter. The outline definer defines outline data for indicating a start pixel and an end pixel of a filling along each scanning line of a drawing region. The divider divides the drawing region into an m × n matrix of drawing subregions. The outline flag setter sets an outline flag for indicating a presence of the outline data for each of the drawing subregions. The filler performs a fill processing for drawing subregions in a case where a continue flag is set for an adjacent drawing subregions and the outline flag is set for each of the drawing subregions. A  continue flag setter sets the continue flag for each of the scanning line, whether a filling continues into an adjacent drawing subregion.
Patent CA-2640730-A1 (CA)
Title: Thermally enhanced tool for friction stirring
Inventor: STEEL RUSSELL J
IPC: B23K20/12
Filed: 2007-01-31
Abstract: A friction stirring tool and a method for removing the catalytic phase from the friction stirring tool having a superabrasive coating by chemically etching, electrolytic etching or similar means to thereby at least partially remove a portion of the secondary catalytic phase metal from the superabrasive coating to thereby enhance the thermal stability of the tool and allow for longer life and the reduction or elimination of chemical reaction between the secondary metallic phase of the tool and a workpiece .