baber/WOPTO huggingface dataset:
Patent CA-2388350-A1 (CA)
Title: Optical spectroscopy device and method for its manufacture
Inventor: REINHARDT ANDREAS
IPC: G01N21/64
Filed: 2000-11-22
Abstract: Disclosed is an optical spectroscopy device (1) and a method for the production thereof. The inventive device comprises at least one light source (8) and at least one integrated spectrometer (3). The optical components of the at least one spectrometer (3) are optical microcomponents (11, 13, 16, 19, 20, 21) which are integrated into the top and/or bottom side (9, 12) of a support plate (2). According to the inventive method, at least one light source (8) is arranged on a support plate (2) and at least one spectrometer (3) is monolithically produced in a three dimensionally integrated form on said support plate (2). The spectrometer produced according to the inventive method (3) is made from optical microcomponents (11, 13, 16, 19, 20, 21).
Patent CA-2389717-A1 (CA)
Inventor: MACKELVIE WINSTON R
IPC: H01M8/04
Filed: 2002-06-25
Abstract: The present invention discloses a process to add a thin, active coating to all of the passageways, ports, and flow field channels of an assembled fuel cell or fuel cell stack. The coating substance may include, alone or in combination, ionomers (such as Nafion®), wicking fibers, catalyst, sealants, and water absorbents. The coating provides, alone or in combination, water management, electrochemistry enhancements, porosity control, and leak-seal functions. The invention is carried out in five steps. In the first step a coating fluid is prepared containing the desired substance(s) and a diluting carrier fluid such as alcohol. In the second step, the coating fluid is pumped or vacuum drawn into the cell/stack via an existing external connections (inlet/outlet ports). In the third step, the surplus coating fluid is removed by purging and/or vacuuming, leaving only a thin, coating or deposit behind. In the fourth step vacuuming and/or heating and/or spinning of the cell/stack is used to evaporate the carrier fluid. In the fifth step the stack is heated to a temperature that sets, inverts micelle structures, or otherwise makes the coating permanent. The process may be repeated to thicken the deposited layer or to add substances successively.
Patent CA-2395090-A1 (CA)
Inventor: WIEDRICH CHARLES R
IPC: C08F18/24
Filed: 2000-12-13
Abstract: A polymerizable composition is described, which composition comprises a polyol(allyl carbonate) monomer, e.g., diethylene glycol bis(allyl carbonate) monomer, and an additive represented by general formula (II), wherein R2 and R6 are each selected independently from hydrogen, C1-C20 linear or branched alkyl, cycloalkyl having from 5 to 7 carbon atoms in the cyclic ring, aryl, C2-C20 linear or branched alkanoyl, cycloalkanoyl having from 5 to 7 carbon atoms in the cyclic ring and aroyl, R2 and R6 each being free or radically polymerizable ethylenically unsaturated groups; R3O and R5 are the same or different, R4O is different than each of R3O and R5O; R3O, R4O and R5O are each independently a divalent residue of an epoxide; x and z are each independently a number from 0 to 200, provided that the sum of x and z is greater than zero; and y is a number from 3 to 200. The additive is present in the composition of the present invention in an amount at least sufficient such that a polymerizate of the composition is substantially free of tinting defects, such as ferns and moons.
Patent CA-2396179-A1 (CA)
Inventor: URANKAR EDWARD JOSEPH
IPC: C08J9/28
Filed: 2001-01-24
Abstract: This application relates to microporous, open-celled polymeric foam materials with physical characteristics that make them suitable for a variety of uses produced from high internal phase emulsions (HIPEs). This application particularly relates to oxidatively stable emulsifiers used to stabilize the HIPE and the foams produced from such HIPEs.
Patent CA-2396920-A1 (CA)
Title: Process for solubilizing glucagon-like peptide 1 (glp-1) compounds
Inventor: RINELLA JOSEPH VINCENT JUNIOR
IPC: A61K38/26
Filed: 2001-01-16
Abstract: Disclosed is a method of preparing a GLP-1 compound that is soluble in aqueo us solution at pH 7.4 from a GLP-1 compound that is substantially insoluble in aqueous solution at pH 7.4. The insoluble GLP-1 compound is dissolved in aqueous base or in aqueous acid to form a GLP-1 solution. The GLP-1 solution  is then neutralized to a pH at which substantially no amino acid racemizatio n of the GLP-1 compounds occurs, after which the soluble GLP-1 compound is isolated from the neutralized solution.
Patent CA-2398789-A1 (CA)
Inventor: TSOTSOU GEORGIA ELENI
IPC: C12Q1/32
Filed: 2001-01-30
Abstract: A process is described for detecting modulation of NAD(P)H and/or a NAD(P)H dependent oxidoreductase ("NDO") in or by a biological system which comprise s NAD(P)H and an NDO. The process comprises generating a detectable marker of NAD(P)H modulation, and detecting said detectable marker. The oxidoreductase  may be cytochrome p450 BM3 from Bacillus megaterium in E.coli.
Patent CA-2401543-A1 (CA)
Inventor: ANDERSEN KETIL STRAND
IPC: G05B13/04
Filed: 2001-03-12
Abstract: The invention relates to a control system, especially one for use in the control of industrial plant such as a polymerisation reactor. In particular, the invention provides a method of controlling a process comprising the steps of: a) generating a first-principle model corresponding to the process; b) inputting data describing the current and desired future process conditions;  c) generating a linear approximation to the model which is valid for said current conditions; d) using said linear approximation to determine an approximate solution to a control problem related to the process; and e) controlling the process using said approximate solution.
Patent CA-2402526-A1 (CA)
Title: Natural gas liquefaction process
Inventor: PAUROLA PENTTI
IPC: F25B9/00
Filed: 2001-03-15
Abstract: The invention relates to a natural gas liquefaction process and particularly to one suited to use offshore. The invention provides a natural gas liquefaction apparatus wherein a carbon dioxide based pre-cooling circuit is provided in a cascade arrangement with a main cooling circuit. The invention also extends to a natural gas liquefaction apparatus wherein a main cooling circuit uses as a refrigerant a gas stream, at least a portion of which is derived from a raw natural gas source.
Patent CA-2405444-A1 (CA)
Title: Unified rotary flow control valve for internal combustion engine cooling system
Inventor: MARSH GREGORY ALAN
IPC: F02B29/04
Filed: 2002-09-26
Abstract: An enhanced split cooling system and method for a turbocharged internal combustion engine including a liquid cooled turbocharger 19 and an engine liquid coolant jacket 18, the system comprising a coolant pump 12 for pumping coolant from a coolant storage tank 16 in heat exchange relationship with the engine jacket 18 and turbocharger 19; an oil cooler 32 having coolant input and output lines; a valve assembly 74, 83 including a mufti-port rotary valve actuated by a single actuator; a first coolant output line connected for conveying coolant from the engine to the valve assembly 74, 83; a radiator 22 connected via a second coolant line for receiving coolant from the valve assembly 74, 83 and having a coolant outflow line to return coolant to the coolant tank 16; an intercooler 28 operatively associated with the turbocharger 19 for passing the coolant in hear exchange relationship with compressed air in the turbocharger 19; a lube oil subcooler 46 coupled by a third coolant flow line to receive coolant from the radiator 22 and having a coolant outflow line selectively couplable through the valve assembly 74, 83 to the oil cooler 32 and the coolant tank 16; an intercooler subcooler 24 coupled by a fourth coolant flow line to receive coolant from the oil subcooler 46 and having a coolant outflow line selectively couplable through the valve assembly 74, 83 to the coolant tank 16 and the intercooler 28; and the valve assembly 74, 83 being independently operable for selectively directing coolant flow through the radiator 22 and subcoolers 46, 24 and the oil cooler 32 and intercooler 28 as a function of engine operating temperature.
Patent CA-2405631-A1 (CA)
Title: System and method for fracturing a subterranean well formation for improving hydrocarbon production
Inventor: RISPLER KEITH
IPC: E21B43/267
Filed: 2002-09-27
Abstract: A method of fracturing a downhole formation according to which a plurality of jet nozzles are located in a spaced relation to the wall of the formation to form an annulus between the nozzles and the formation. A non-acid containing stimulation fluid is pumped at a predetermined pressure through the nozzles, into the annulus, and against the wall of the formation, and a gas is introduced into the annulus so that the stimulation fluid mixes with the gas to generate foam before the mixture is jetted towards the formation to form fractures in the formation. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure; and is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims under 37CFR 1.72.
Patent CA-2406696-A1 (CA)
Title: Apparatus for sanitary wet milling
Inventor: CZEKAI DAVID A
IPC: B02C17/16
Filed: 2001-04-26
Abstract: Improved cleanability and contamination prevention are provided in a wet milling apparatus (1) for the production of pharmaceutical grade milled products. The advantages are provided by a milling agitator (40) that is characterized by a smooth, seamless agitating surface, without crevices or seams which might accumulate contamination and which might prevent removal of contamination during cleaning.  The use of polymeric milling media reduces wear on the agitator and permits the agitator to be constructed with permanent, smooth weld joints.  Seamless joints are also provided on the interior of the milling chamber (60) and sanitary, threadless fasteners are provided for the media separation screen (81) and other milling fittings.
Patent CA-2406811-A1 (CA)
Title: Foodstuffs containing mucorales fungi
Inventor: BIJL HENRIK LOUIS
IPC: A23L31/00
Filed: 2001-03-12
Abstract: The preparation of an edible substance for use in a foodstuff is described which comprises fungal cells of the order Mucorales. The cells are grown in a fermentor vessel in an aqueous liquid which is mixed during fermentation, and fermentation allowed to finish. The fungal cells are kept in the vessel and allowed to ripen, the cells' own RNAses reducing the intracellular RNA content. Fungi of this order may thus have a low RNA content and therefore no heating step, to reduce their RNA content, is necessary. The fungal cells are removed and processed into the edible substance. This substance is then processed into a foodstuff. This avoidance of heat has also resulted in better tasting foodstuffs.
Patent CA-2408259-A1 (CA)
Inventor: ANSLEY DAVID A
IPC: G02B7/198
Filed: 2002-02-14
Abstract: A scanning system (10) and a method permit scanning a desired field-of-view within a maximized field-of-regard at a constant speed without reversing the  scan direction about a primary axis (38). The system includes mirror (20) which rotates about the primary axis (38). The mirror (20) is supported for rotation about a flip axis (40) which is perpendicular to the primary axis (38). Rotation of the mirror (20) about the primary axis (38) is divided int o a scan period during which the field-of-view is scanned by the mirror (20), and a flip period during which the mirror (20) rotates about the flip axis (40). The mirror (20) is mounted in a gimbal for independent rotation about a secondary axis (24) which is parallel to the primary axis (38). Rotation of the mirror (20) about the secondary axis (24) provides an adjustment of the mirror orientation such that at the end of the scan period the mirror (20) faces the end of the field-of-view, and at the end of the flip period the mirror (20) faces the beginning of the field-of-view.
Patent CA-2410984-A1 (CA)
Title: Applicateur a expansion pour sac de recuperation de dechets organiques humains
Inventor: SUTTON THOMAS
IPC: A61F13/15
Filed: 2001-06-19
Abstract: La présente invention concerne des sacs de récupération de déchets organiques humains pour bébés, enfants ou adultes, destinés à être attachés à l'utilisateur. L'invention concerne en particulier un applicateur adapté pour lesdits sacs de récupération, pouvant être utilisé pour placer de manière précise et facile le sac de récupération dans la région périanale ou génito-urinaire de l'utilisateur. L'invention concerne un applicateur (40) comprenant au moins une section (42) de manipulation et au moins une zone (44) de contact, et s'étendant dans au moins une direction d'expansion suite à l'application d'une force entre la section (42) de manipulation et la zone (44) de contact.
Patent CA-2413468-A1 (CA)
Inventor: CORTESE RICCARDO
IPC: C12N1/15
Filed: 2001-06-15
Abstract: A transcription factor, which is a transcriptional activator or a transcriptional repressor, comprising a DNA-binding domain and a transcriptional activator or repressor domain, and optionally a regulatory domain for ligand-dependent DNA binding and/or transcriptional activation or repression by the transcription factor, wherein the transcription factor is chimeric, comprising a HNF1 polypeptide DNA-binding domain and a transcriptional activator or repressor domain of a different polypeptide, with the proviso that where the transcription factor is a transcriptional activator comprising a transcriptional activator domain the transcription factor does not comprise a regulatory domain which binds AcylHSL or an analogue thereof whereby upon AcylHSL binding DNA binding function of the DNA-binding domain is activated. A transcriptional activator comprises a human HNF1 polypeptide DNA-binding domain, a human estrogen receptor alpha regulatory domain containing a G521R mutation, and a human p65 activation domain.
Patent CA-2416413-A1 (CA)
Inventor: BOYER CHRISTOPHER T
IPC: B25G1/10
Filed: 2003-01-14
Abstract: There is provided with a power tool a housing having a motor mounted therein for driving a work element mounted below the bottom of the housing for working on a workpiece. The power tool has first and second handles extending from opposite sides thereof, with at least one handle having either or both an enlarged portion and an enhanced gripping portion to facilitate control over the tool. The gripping portion may have an enhanced texture surface, such as an elastomer surface, for an operator to grip the tool. In another form, the power tool may include a switch movable between a first position wherein the power tool is in active state and a second position wherein the power tool is in a de-active state. A lock may be connected to the power tool and movable between a release positron wherein the switch is freely movable between its first and second positions and a lock position wherein the switch is locked in the second position. so that the power tool can remain in the active state without assistance from an operator. T:he power tool may also include a recess for retaining an accessory to be used in connection therewith.
Patent CA-2417739-A1 (CA)
Title: Control of stress corrosion cracking growth by operational pressure control
Inventor: WEIXING CHEN
IPC: C21D7/12
Filed: 2003-01-30
Abstract: A method of reducing stress corrosion cracking in a member made of metal, such as a pipe, comprises applying a load to the member to prevent stress corrosion cracking.
Patent CA-2421204-A1 (CA)
Title: Method and system for detecting nucleic acids
Inventor: LICHTENSTEIN AMIR
IPC: C12Q1/68
Filed: 2001-08-29
Abstract: A method for the detection of a target nucleic acid in a sample containing a mixture of nucleic acids. The method comprises (a) providing a solid surface;  (b) attaching to the solid surface an oligonucleotide probe complementary to a segment of the target nucleic acid; (c) contacting the surface with the sample, thereby allowing the probe to bind the target nucleic acid; (d) incubating the bound target nucleic acid with the 4 nucleotide types and a replication biocatalyst thereby forming a multi-stranded nucleic acid assembly, wherein at least one of the nucleotide types is bound by a label;  and (e) detecting the label on the multi-stranded nucleic acid assembly, thereby detecting the target nucleic acid. Also disclosed are a system for identifying a target nucleic acid sequence in a sample and a kit for use in the method.
Patent CA-2421364-A1 (CA)
Inventor: GODDARD AUDREY
IPC: A61P35/00
Filed: 1999-03-08
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Patent CA-2422667-A1 (CA)
Inventor: SAKON TADASHI
IPC: H01M8/02
Filed: 2001-09-07
Abstract: La présente invention concerne un article composite qui comprend une partie étanche, pouvant facilement être produite dans une région à haute température de 800 DEG  ou plus, est très fiable et présente des caractéristiques très satisfaisantes lors de cycles thermiques. Cet article composite est par conséquent adapté à un usage dans un appareil de production d'oxygène pur, d'air enrichi en oxygène ou d'un gaz similaire, dans un réacteur à membrane barrière, représenté par celui permettant une oxydation partielle d'un hydrocarbure gazeux, une pile à combustible à oxyde solide, un appareil de purification d'oxygène gazeux, un échangeur thermique ou un appareil similaire. L'article composite selon cette invention permet d'améliorer la possibilité de commercialisation d'appareils dont le développement a connu un retard du à une étanchéification insatisfaisante, dans une vaste gamme d'applications. L'utilisation dudit article composite dans les appareils susmentionnés peut notamment favoriser de façon considérable l'accélération de leur développement.
Patent CA-2422803-A1 (CA)
Title: Detection of cox-2 activity and anandamide metabolites
Inventor: KOZAK KEVIN R
IPC: C12Q1/26
Filed: 2001-08-07
Abstract: The present invention relates generally to cyclooxygenase enzymes (COX) and more particularly the COX-2 enzyme. The present invention provides compositions, methods and articles of manufacture (kits) for determining the COX-2 activity in a sample of a subject, such as a patient or a cell culture.  The present invention is useful in monitoring inflammation and cancer, or other disease processes, in patients in a clinical setting.
Patent CA-2427981-A1 (CA)
Title: System and method of siphoning messages from a mobile network to an alternative network
Inventor: ARAVAMUDAN MURALI
IPC: H04W76/04
Filed: 2001-11-21
Abstract: A proxy switch, communication methods, and communication logic for use in a mobile network are described. A proxy switch is deployed between a base station subsystem and a mobile station center. It receives signaling messages and either retransmits them, blocks them, converts them, or siphons them to an alternative network. Besides providing an ability to offload mobile traffic it provides a platform for new communication services. A proxy switch includes signaling message handling logic for sending and receiving signaling messages to and from the MSC on a first signaling link and sending and receiving messages to and from the BS on a second signaling link; wherein the second link has a mapped correspondence to the first link.
Patent CA-2428237-A1 (CA)
Title: Process for the preparation of carbostyril derivatives
Inventor: MEUNIER JEAN-FRANCOIS
IPC: C07D487/10
Filed: 2003-05-08
Abstract: A process for preparing carbostyril derivatives such as aripiprazole is described.    Dichlorophenylpiperazine or an acid addition salt thereof is reacted with a compound of formula X-C4H8-Y or X-C4H6-Y to produce a novel quaternary spiro ammonium salt intermediate which is optionally isolated and purified. The quaternary spiro ammonium salt intermediate is reacted with 7-hydroxydihydrocarboxystyryl to produce the carbostyril derivative.
Patent CA-2429034-A1 (CA)
Inventor: WEINSTEIN DAVID E
IPC: G01N33/574
Filed: 2001-11-07
Abstract: La présente invention concerne des méthodes d'inhibition de la prolifération des astrocytes et des cellules tumorales astrocytiques. L'invention concerne également des méthodes de traitement d'un état pathologique associé à un défaut dans la prolifération des astrocytes chez un sujet. De plus, la présente invention concerne des compositions pharmaceutiques comprenant une protéine CD81 ou un acide nucléique et un excipient acceptable d'un point de vue pharmaceutique. La présente invention concerne enfin une méthode permettant de déterminer si un sujet est atteint d'un astrocytome, et une méthode d'évaluation de l'efficacité d'une thérapie de traitement de l'astrocytome.
Patent CA-2429388-A1 (CA)
Title: Pressure sensitive adhesive sheet
Inventor: MURAKAMI YOSHIHIDE
IPC: C09J7/38
Filed: 2003-05-22
Abstract: A pressure sensitive adhesive sheet which has a moderate adhesive strength, does hardly add physical stimuli to the adherend at the time of peeling and also has such a good processing suitability that the support does not generate swelling deformation by transfer of a liquid component from the adhesive layer. The pressure sensitive adhesive sheet has an adhesive layer formed from a resin composition comprising an acrylic acid ester polymer, a carboxylic acid ester having 16 or more carbon atoms which is compatible with the acrylic acid ester polymer and is liquid or paste at ordinary temperature, and a crosslinking component, and a film supporting the adhesive layer, comprising a polyether urethane resin obtained by allowing a polyol component to react with a polyisocyanate component, wherein the polyol component constituting the urethane resin contains at least one kind of polyether polyol having a polyoxyalkylene backbone represented by a specified repeating unit.
Patent CA-2430937-A1 (CA)
Title: Inflammatory cytokine secretion inhibition
Inventor: BOLTON ANTHONY ERNEST
IPC: A61K35/14
Filed: 2001-12-05
Abstract: A process of decreasing the expression of one or more of the inflammatory cytokines IFN-y and IL-6 from cells in a mammalian patient, comprises administering to the patient an effective amount of stressed mammalian blood cells, said stressed cells having been extracorporeally subjected to at least one stressor selected from oxidative stress and ultraviolet radiation. These findings are indicative of the use of the process in the treatment for alleviation of chronic fatigue syndrome.
Patent CA-2432222-A1 (CA)
Title: Pyrazole compounds useful as protein kinase inhibitors
Inventor: KNEGTEL RONALD
IPC: A61K31/55
Filed: 2001-12-19
Abstract: This invention describes novel pyrazole compounds of formula (IIIC): wherein R1 is T-Ring D, wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; Rx, Ry, R2, and R2' are as described in the specification. The compounds are useful as protein kinase inhibitors, especially as inhibitors of Aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease.
Patent CA-2434329-A1 (CA)
Title: Method of barge mining oil sands
Inventor: WALSH GLENN
IPC: E21C45/00
Filed: 2003-07-03
Abstract: Oil sands are flooded and then dredge mined via barges. The mined ore and water form a slurry which is pumped to a floating plant where the slurry may be processed, or the bitumen may be extracted. The process ensures the oil sands do not freeze, making excavation easier during the winter months, and reducing slowdowns due to frost lumps. The process also eliminates the need to use shovels and trucks in the mining pits, resulting in an overall reduction in costs and a reduction in carbon dioxide emissions.