baber/WOPTO huggingface dataset:
Patent NZ-240323-A (NZ)
Title: Absorbent article - casing and side flap edges form liquid barrier devices
Inventor: WIDLUND URBAN
IPC: A61F13/00
Filed: 1991-10-23
Abstract: PCT No. PCT/SE91/00735 Sec. 371 Date Jul. 2, 1993 Sec. 102(e) Date Jul. 2, 1993 PCT Filed Oct. 31, 1991 PCT Pub. No. WO92/07536 PCT Pub. Date May 14, 1992.An absorbent article such as a sanitary napkin or a guard for mildly incontinent persons, comprising an elongated absorbent pad (3) enclosed between a liquid-permeable casing sheet (1) facing the wearer in use of the article and a liquid-impermeable casing sheet (2). At least one of the casing sheets extends laterally beyond the absorbent pad forming an outwardly projecting, longitudinally extending edge. Flexible side-flaps (5, 6) are arranged at the long side edges of the absorbent pad (3) and are intended, when the article is used, to be folded around the edges of the wearer's underpants or like garment (9) in the crotch part thereof and attached to the outside of the underpants. Uplifted liquid barrier devices (10, 11) are provided on that side of the article which faces the wearer in use on both sides of the absorbent pad (3) along at least parts of the long side edges thereof between the absorbent pad and the flexible side-flaps. An end portion (12, 13) of each side-flap (5, 6) is attached to the corresponding outwardly projecting edge of the casing sheet(s) on that side thereof which, when the side-flaps are folded against the side of the article distal from the wearer in use, is facing away from the wearer. This end portion (12, 13) has an extent corresponding to the height desired for the respective liquid barrier device (10, 11).
Patent NZ-241270-A (NZ)
Title: Milking machine pulsator with adjustable slide valve for eliminating drag
Inventor: ICKING FRIEDRICH
IPC: A01J5/12
Filed: 1992-01-10
Abstract: A pulsator for milking machines comprises a bolt which travels back and forth in a housing and activates a slide. The slide alternately connects the pulsator's outlets to a source of vacuum and to the atmosphere. A diaphragm accommodated in a chamber at each end of the slide moves the bolt back and forth. An alternator is triggered by the slide as it arrives at one end or the other of its stroke. The alternator connects the chambers back and forth and alternately to the source of vacuum and to the atmosphere. The distance between the slide and at least one of the diaphragms is varied to suppress stagger.
Patent NZ-242139-A (NZ)
Title: Conversion of the proline residue in a macrolactone to dehydroproline using a microorganism or acellular preparation from it
Inventor: BLANCHE FRANCIS
IPC: C12P21/04
Filed: 1992-03-26
Abstract: The invention relates to a process for the enzymatic preparation of a polyunsaturated macrolactone of the group A streptogramins by means of a microorganism or an acellular preparation derived from this microorganism, capable of oxidising the 2-3 bond of the D-proline of macrolactones to dehydroproline.
Patent NZ-245201-A (NZ)
Title: An ethanolamine benzoate derivative and pharmaceutical compositions thereof
Inventor: WIERZBICKI MICHEL
IPC: A61P3/06
Filed: 1992-11-20
Abstract: New ethanolamine benzoate derivatives, which can be used as medicaments and which correspond to the formula: 
<IMAGE>
 in which R is as defined in the description, in the racemic and enantiomeric forms. 
<??>These new derivatives and their physiologically tolerable salts can be used in therapeutics, especially for the treatment of syndrome X, combining intolerance to glucose, hyperinsulinemia, dyslipemia and hypertension, and for the treatment of hypertension in insulin-resistant subjects or those having one or a number of metabolic abnormalities.
Patent NZ-261420-A (NZ)
Title: 8-azabicyclo[3,2,1]octane (ecgonine and ecgonidine) derivatives and medicaments
Inventor: SOMERS LOWELL
IPC: A61K31/00
Filed: 1993-12-23
Abstract: The present invention relates to a novel class of benzoylecgonine, ecgonine and ecgonidine derivatives which are useful for preventing and treating immunoregulatory disorders, neuromuscular disorders, joint disorders, connective tissue disorders, circulatory disorders and pain. The compounds of this invention are conveniently obtained by chemical synthesis. Accordingly, this invention also relates to methods for preparing the benzoylecgonine, ecgonine and ecgonidine derivatives and to pharmaceutical compositions containing these derivatives.
Patent NZ-270965-A (NZ)
Title: Tricyclic substituted hydroxamic acid derivatives and pharmaceutical compositions thereof
Inventor: BROADHURST MICHAEL JOHN
IPC: A61K31/454
Filed: 1995-04-20
Abstract: The invention provides hydroxamic acid derivatives of the general formula <CHEM> wherein R<1> represents cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl; R<2> represents a saturated 5- to 8-membered monocyclic or bridged N-heterocyclic ring which is attached via the N atom and which, when it is monocyclic, optionally contains NR<4>, O, S, SO or SO2 as a ring member and/or is optionally substituted on one or more C atoms by hydroxy, lower alkyl, lower alkoxy, oxo, ketalized oxo, amino, mono(lower alkyl)amino, di(lower alkyl)amino,carboxy, lower alkoxycarbonyl, hydroxy-methyl, lower alkoxymethyl, carbamoyl, mono(lower alkyl)-carbamoyl, di(lower alkyl)carbamoyl or hydroxyimino; R<3> represents a 5- or 6-membered N-heterocyclic ring which (a) is attached via the N atom, (b) optionally contains N, O and/or S, SO or SO2 as an additional ring member, (c) is substituted by oxo on one or both C atoms adjacent to the linking N atom and (d) is optionally benz-fused or optionally substituted on one or more other C atoms by lower alkyl or oxo and/or on any additional N atom(s) by lower alkyl or aryl; R<4> represents hydrogen, lower alkyl, aryl, aralkyl or a protecting group; m stands for 1 or 2 and n stands for 1-4, and pharmaceutically acceptable salts thereof, which are collagenase inhibitors useful in the control or prevention of degenerative joint diseases such as rheumatoid arthritis and osteoarthritis or in the treatment of invasive tumours, atherosclerosis or multiple sclerosis. They can be manufactured either by hydroxamidating a corresponding novel carboxylic acid or by deprotecting a corresponding novel benzyloxycarbamoyl compound.
Patent NZ-289531-A (NZ)
Title: Disc refining elements for lignocellulose with bar and groove patterns to allow release of generated steam
Inventor: ROHDEN LENNART
IPC: B02C7/12
Filed: 1995-06-26
Abstract: PCT No. PCT/SE95/00779 Sec. 371 Date Nov. 8, 1996 Sec. 102(e) Date Nov. 8, 1996 PCT Filed Jun. 26, 1995 PCT Pub. No. WO96/00616 PCT Pub. Date Jan. 11, 1996Apparatus for refining lignocellulose-containing material is disclosed including a pair of opposed refining disks defining a refining gap for the lignocellulose-containing material, at least one of the refining disks including an outer refining zone section which includes three refining zones including radially extending bars and corresponding radially extending grooves in which the first and third refining zones have a different bar density than the intermediate or second refining zone. Apparatus is also disclosed which includes a pair of opposed refining surfaces in which each disk refiner includes a pair of refining zones with one of each pair on each disk having a different bar density, and with the two zones being radially offset so that the like refining zones in each disk do not overlap with each other.
Patent NZ-291683-A (NZ)
Title: Cup to can drawing press: reciprocating ram wipers separate drawing coolant from ram hydrostatic bearing fluid
Inventor: MAIN RALPH
IPC: B21D37/18
Filed: 1995-08-16
Abstract: A bodymaker that transforms shallow metal cups into elongated can bodies includes a reciprocated ram which, during its forward stroke, drives the cups through a set of graduated circular dies. Ring shaped wipers engage the outer cylindrical surface of the ram and are arranged so that a first of the wipers scrapes tool coolant from the ram as the latter moves rearward and a second of the wipers scrapes hydraulic bearing fluid from the ram as the latter moves forward. The wipers are provided with flexible flaps that are in relatively low pressure frictional engagement with the ram resulting in only a very low temperature rise for the wipers to increase operating life thereof at production rates of approximately 400 per minute for cans of 2+E,fra 1/2+EE  inch diameter.
Patent NZ-298769-A (NZ)
Title: use of progesterone-antagonistic and anti-estrogen compounds in a single dose for female contraception
Inventor: CHWALISZ KRISTOF
IPC: A61K31/445
Filed: 1995-12-23
Abstract: A progesterone antagonistic compound and an estrogen-antagonistic compound, each at a non-ovulation inhibiting dosage in a single dosage unit, are used in the manufacture of a medicament for female contraception.
Patent NZ-301153-A (NZ)
Title: Transdermal delivery of acid-labile drugs; compositions and methods
Inventor: LI CHENSHENG
IPC: A61K47/18
Filed: 1996-01-11
Abstract: A transdermal penetration-enhancing, drug acid-lability reducing composition and related method are described.  Specifically, the transdermal composition comprises: (a) a therapeutically effective amount of a pharmacologically active drug which is subject to acid catalyzed degradation; (b) a pharmaceutically acceptable carrier substantially free of a lower alkanol; and (c) a penetration-enhancing amount of a functional derivative of a fatty acid. Such compositions increase the usefulness of transdermal compositions that rely upon an organic acid such as oleic acid penetration enhancer.
Patent NZ-316453-A (NZ)
Title: Method of sailing a boat, and sailing vessel
Inventor: KETTERER KLAUS
IPC: B63H9/06
Filed: 1996-07-31
Abstract: PCT No. PCT/DE96/01424 Sec. 371 Date Jan. 28, 1998 Sec. 102(e) Date Jan. 28, 1998 PCT Filed Jul. 31, 1996 PCT Pub. No. WO97/06051 PCT Pub. Date Feb. 20, 1997A sailing method and a sailing boat (1) are designed for low or even non-drift sailing, wherein the total power provided by the sail (5) is established, after which the keel (3) is adjusted in terms of its effective surface and/or its curvature and/or the shape of its profile and/or its setting angle in relation to the boat's hull, possibly taking into account the water current and the weight of the boat, in order to produce an optimized counteracting force. To this end the keel (3) is designed as a multi-section, unballasted fin keel (33) which can be completely retracted into the boat's hull (2) and can be pivoted relative to the centerline of the boat (10), and the sections (34, 37, 38) of which are fitted together via hinges (35, 39) in order to produce a variable curvature.
Patent NZ-316662-A (NZ)
Title: Use of vitamin D2 or vitamin D4-derivatives for the manufacture of a medicament for the treatment of secondary hyperparathyroidism
Inventor: KNUTSON JOYCE C
IPC: A61K33/16
Filed: 1996-04-03
Abstract: A method for lowering or maintaining serum parathyroid hormone in human patients suffering from hyperparathyroidism secondary to end stage renal disease using 1a -OH vitamin D2, 1a,24(S)-(OH)2 vitamin D2, 1a -OH vitamin D4 or 1a,24(R)-(OH)2 vitamin D4 is described.
Patent NZ-323388-A (NZ)
Title: Quinoline-4-carboxamide derivatives, their preparation and their use as neurokinin 3 (NK-3) and neurokinin 2 (NK-2) receptor antagonists
Inventor: GIARDINA GIUSEPPE ARNALDO MARI
IPC: C07D215/52
Filed: 1996-11-22
Abstract: compound of above formula (I), or a salt thereof, or a solvate thereof, wherein, Ar is an optionally substituted aryl or a C5-7 cycloalkdienyl group, or an optionally substituted single or fused ring aromatic heterocyclic group; R is C1-6 alkyl, C3-7 cycloalkyl, C3-7 cycloalkylalkyl, optionally substituted phenyl or phenyl C1-6 alkyl, an optionally substituted five-membered heteroaromatic ring comprising up to four heteroatoms selected from O and N, hydroxy C1-6 alkyl, amino C1-6 alkyl, C1-6 alkylaminoalkyl, di C1-6 alkylaminoalkyl, C1-6 acylaminoalkyl, C1-6 alkoxyalkyl, C1-6 alkylcarbonyl, carboxy, C1-6 alkoxycarbonyl, C1-6 alkoxycarbonyl C1-6 alkyl, aminocarbonyl, C1-6 alkylaminocarbonyl, di C1-6 alkylaminocarbonyl, halogeno C1-6 alkyl; or R is a group -(CH2)p- wherein p is 2 or 3 which group forms a ring with a carbon atom of Ar; R1 represents hydrogen or up to four optional substituents selected from the list consisting of: C1-6 alkyl, C1-6 alkenyl, aryl, C1-6 alkoxy, hydroxy, halogen, nitro, cyano, carboxy, carboxamido, sulphonamido, C1-6 alkoxycarbonyl, trifluoromethyl, acyloxy, phthalimido, amino or mono- and di-C1-6 alkylamino; R2 represents hydrogen, C1-6-alkyl, hydroxy, halogen, cyano, amino, mono- or di-C1-6-alkylamino, alkylsulphonylamino, mono- or di-C1-6-alkanoylamino wherein any alkyl group is optionally substituted with an amino group or with a mono- or di-alkylamino group, or R2 is a moiety -X-(CH2)n-Y wherein X is a bond or -O- and n is an integer in the range of from 1 to 5 providing that when X is O-n is only an integer from 2 to 5 and Y represents a group NY1Y2 wherein Y1 and Y2 are independently selected from hydrogen, C1-6-alkyl, C1-6-alkenyl, aryl or aryl-C1-6-alkyl or Y is hydroxy, halogen or an optionally substituted N-linked single or fused ring, heterocyclic group, R3 is branched or linear C1-6 alkyl, C3-7 cycloalkyl, C4-7 cycloalkylalkyl, optionally substituted aryl, or an optionally substituted single or fused ring aromatic heterocyclic group; and R4 represents hydrogen or C1-6 alkyl.
Patent NZ-329320-A (NZ)
Title: Volumetric infusion pump with tube loading automatically transversely to axis of tube
Inventor: ALLEN TIM
IPC: F04B53/16
Filed: 1997-03-21
Abstract: An infusion pump which is operable to pump a fluid through a tube is described. The pump comprises a shuttle having upstream and downstream sides which is operable to cyclically deform and reform the tube, a first valve associated with the upstream side of the shuttle, a second valve associated with the downstream side of the shuttle and a cam having a first face which is operable to actuate the shuttle and a second face which is operable to actuate the first and second valves.
Patent NZ-332399-A (NZ)
Title: 4,4a,5,6-tetrahydro-pyrido[3,4-h]cinnolin-3-one derivatives and medicaments
Inventor: BANTICK JOHN
IPC: A61P29/00
Filed: 1997-05-20
Abstract: A compound of formula I or pharmaceutically derivatives thereof is claimed wherein: X is -(CH2)n- or -CH=CH-; n is 1 to 3; Y is -CH2- or -CO-; R1 is H or together with R2 is a bond; R2 is H, alkyl or together with R1 is a bond; Ar1 is optionally substituted thiazolyl, phenyl, pyridyl, pyrimidinyl, 2-benzothiazolyl, 2- or 3-quinolyl or 2-quinoxalinyl; provided that when Y is -CH2- then R1 and R2 do not together represent a bond. A process for preparing a compound of formula I is claimed. A pharmaceutical composition containing a compound of formula I useful in the treatment of allergic and inflammatory disease of the airways, prophylactic and therapeutic treatment of AIDS, the prevention of chronic rejection of allografts mediated by humoral immunity and the treatment of autoimmune diseases is claimed.
Patent NZ-335350-A (NZ)
Title: Sensing change of fluid within space
Inventor: LANG EDO
IPC: E03D11/00
Filed: 1999-04-22
Abstract: A sensor 10 including a temperature dependent resistor 12 and a heating resistor 16 in a casing 20 are placed into an environment to detect a change in the fluid condition of the environment, for example, the flushing of a toilet or urinal, the spillage of a liquid, or the lowering of a liquid level.  The temperature dependent resistor is heated to a temperature which lies outside the range of temperatures of the fluid, and in the passive phase, the fluid in the vicinity of the sensor is brought to a constant passive temperature by heat transfer between the sensor element and the surrounding fluid so that the sensor resistance, to which a voltage is applied, provides an approximately constant passive output voltage.  In an active phase, the fluid condition of the environment changes which changes the heat transfer between the sensor and the fluid so that sensor produces an active output voltage.  If the difference between the active and passive output voltages exceeds a threshold, an indicator signal is generated.
Patent NZ-335974-A (NZ)
Title: Hypocholesteremic agents containing tocopherols and phytostanol (phytosterols)
Inventor: WEITKEMPER NORBERT
IPC: A61K31/56
Filed: 1997-11-19
Abstract: Composition of hypocholesteremic agents containing (a) phytostanol ester and (b) tocopherols. The phytostanol ester is characterised as b-sitostanol ester shown in Formula (I). The tocopherol is shown in Formula (II). The composition could be encapsulated gelatin where it may be administered orally in high doses. Where Formula (I) is composed of: R1 is an aliphatic, linear or branched C2-22alkyl group. Where Formula (II) is composed of: R2, R3 and R4 is independently hydrogen or methyl groups.
Patent NZ-336271-A (NZ)
Title: Pharmaceutical compositions containing ziprasidone useful in treating psychosis
Inventor: BUSCH FRANK ROBERT
IPC: A61K47/26
Filed: 1999-06-14
Abstract: A composition comprising crystalline ziprasidone of the formula above having a mean particle size less than or equal to 85mm and a diluent useful for treating psychosis.
Patent NZ-337844-A (NZ)
Title: 6,7-disubstituted-4-aminopyrido[2,3-d]pyrimidine compounds
Inventor: BHAGWAT SHRIPAD S
IPC: C07D471/04
Filed: 1998-04-16
Abstract: Compounds of formula (I) wherein, R1 and R2 are independently selected from hydrogen and loweralkyl; R3 is selected from alkenyl, alkyl, alkynyl, aryl, arylalkyl and heterocycle; and R4 is selected from aryl and heterocycle; wherein each of the foregoing aryl, heterocycle, and aryl part of the arylalkyl is unsubstituted or substituted with one, two, or three substituents independently selected from the group consisting of F, Cl, Br, I, cyano, carboxamido, hydroxy, loweralkoxy, loweralkyl, loweralkenyl, loweralkynyl, amino, loweralkylamino, di(loweralkyl)amino, N-loweralkyl-N-loweralkoxyamino, trifluoromethyl, and methoxymethyl. The compounds act to inhibit adenosine kinase and are useful in treating ischemia, neurological disorders, nociperception, inflammation, immunosuppression, gastrointestinal disfunctions, diabetes and sepsis.
Patent NZ-500743-A (NZ)
Title: Container carrier having an integral panel for merchandising information
Inventor: SLOMSKI EDWARD J
IPC: B65D71/50
Filed: 1999-11-02
Abstract: Provided is a package for a plurality of elongated containers (5) unitized with a flexible container carrier (10) has the carrier (10) constructed from a plastic planar sheet having a plurality of first receiving openings (20) positioned near a first lateral edge of the sheet and a number of second receiving openings (25) at a distance from the first receiving openings (20).  Each of the first receiving openings engages with a neck portion (7) of one of the elongated containers (5) and each of the second receiving openings (25) engages with a middle portion of one or more of the elongated containers (5).  A panel (40) integral with the sheet is positioned on an outer surface of the package (1) between the first receiving openings (20) and the second receiving openings (25).  The dimensions of the panel (40) correspond with the dimensions of the package to create a package having a large promotional area for advertising and product information
Patent NZ-500748-A (NZ)
Title: Methods for the treatment of gastrin-dependent tumours comprising active or passive immunisation with an anti-CCK-B/gastrin receptor immunogen or anti-CCK-B/gastrin receptor antibodies
Inventor: CAPLIN MARTYN
IPC: C07K14/72
Filed: 1998-05-12
Abstract: Immunogens, immunogenic compositions and a method for the detection and treatment of gastrin-dependent tumours are discussed. The immunogens comprise a natural or synthetic peptide from the gastrin/cholecystokinin (CCK)-B receptor conjugated to a spacer amino acid sequence and an immunogenic protein carrier, such as diphtheria toxoid, tetanus toxoid, or bovine serum albumin.  The immunogens are capable of inducing antibodies in vivo which bind to the CCK-B/gastrin receptors on tumour cells, thereby preventing growth stimulating peptide hormones from binding to the receptors and thereby inhibiting tumour cell growth. Methods of immunization against the CCK-B/gastrin receptor include active and passive immunization. For active immunisation, a patient is immunized with an immunogen. The immunogen stimulates the production of antibodies against the CCK-B/gastrin receptor on tumour cells.  The antibodies are specific to the NH2-terminal end of the receptor and upon binding are internalised and rapidly translocated into the cytoplasm and into the nucleus of the tumour cells. This rapid internalisation of the antibody/receptor complex in turn causes the affected tumour cells to undergo apoptosis or suicide. For passive immunization, the antibodies against the CCK-B/gastrin receptor are administered to a patient in a sufficient concentration to bind to the CCK-B/gastrin receptors of the tumour cells and the antibodies block the binding of the peptide hormones to the receptor.  Preventing binding of the hormones to their receptor inhibits the growth-stimulus pathway of the tumour cells, thereby inhibiting the growth of the hormone-dependent tumours. The antibodies for human therapy may be chimeric, humanized, or human monoclonal antibodies which are produced by known methods.  The anti-CCK-B/gastrin receptor antibodies may be further conjugated to cytotoxic molecules such as cholera toxin, or to molecules labelled with radioactive molecules, such as isotopes 125I and 131I, to enhance the killing of the tumour cells.
Patent NZ-503489-A (NZ)
Title: Natural humanized antibody, method of production and pharmaceutical composition
Inventor: TSUCHIYA MASAYUKI
IPC: C12N1/21
Filed: 1998-10-02
Abstract: A method for preparing a humanized antibody comprises conducting a homology search for the framework region (FR) of a primary design antibody. A human FR retaining the artificial amino acid residue contained in the FR of the primary design antibody and having a homology therewith is selected. The humanized antibody comprising the selected FR is prepared by conventional technology. The humanized antibody contains a complementarity determining region (CDR) derived from a first animal species and the FR derived from a second animal species. The FR comprises an amino acid sequence having amino acid residue different from the FR used for CDR-grafting by one or a plurality of amino acid residues. The FR has been replaced with an FR derived from a second animal species and has the same amino acid residues as said different amino acid residue at the same positions. Also described is DNA encoding the antibody and an expression vector comprising that DNA and a pharmaceutical composition comprising the antibody.