baber/WOPTO huggingface dataset:
Patent CA-2508840-A1 (CA)
Inventor: KETNER RODNEY JAMES
IPC: A61K9/16
Filed: 2003-12-09
Abstract: La présente invention se rapporte à une forme posologique qui renferme (1) une dispersion amorphe solide comprenant un inhibiteur de protéine de transfert d'ester de cholestéryle et un polymère acide neutralisé ou neutre et (2) un inhibiteur de HMG-CoA réductase. La forme posologique assure une stabilité chimique améliorée à l'inhibiteur de HMG-CoA réductase.
Patent CA-2510228-A1 (CA)
Inventor: POSNER GARY H
IPC: C07C401/00
Filed: 2003-12-18
Abstract: La présente invention concerne des analogues à cycle D et à chaînes latérales de la 1.alpha.,25-dihydroxyvitamine D¿3?, des compositions renfermant ces composés et des méthodes d'utilisation de ces composés comme inhibiteurs sélectifs de la CYP24. Les composés de l'invention sont utiles en particulier pour le traitement de maladies présentant une modulation des taux de la 1.alpha.,25-dihydroxyvitamine D¿3?, telles que les troubles impliquant une prolifération cellulaire.
Patent CA-2510252-A1 (CA)
Title: Conveying device for baked goods
Inventor: ANDERL JOHANN
IPC: A21C15/00
Filed: 2003-12-03
Abstract: The invention relates to a conveying device for baked goods in which a conveying unit (1) that is connected to a heating device is also connected t o a supplying device (2) and to a removal device (3). A simple and compact design is obtained by virtue of the fact that the conveying unit (1) has a helical surface (1.2), which can be vibrated by means of a vibrating drive (1.1) and which is provided for conveying the baked goods upward. The supplying device is connected in the lower area of the conveying unit (1), a nd the removal device is connected in the upper area of the conveying unit (1).
Patent CA-2510337-A1 (CA)
Title: Topoisomerase-targeting agents
Inventor: LIU LEROY F
IPC: C07D491/04
Filed: 2003-11-12
Abstract: The invention provides compounds of formula I or formula (II), wherein: the bond represented by --- is a single bond or a double bond, and R1-R5, X, and Y have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutica l compositions comprising a compound of formula (I or II), processes for preparing compounds of formula (I or II), intermediates useful for preparing compounds of formula (I or II), and therapeutic methods for treating cancer and other topoisomerase related conditions using compounds of formula (I or II).
Patent CA-2510763-A1 (CA)
Inventor: NAAM RAMEZ
IPC: G06F17/30
Filed: 2005-06-27
Abstract: La méthode et le système proposés permettent de classer des résultats de recherche en fonction des préférences de l'utilisateur. Cette méthode comprend le contrôle des sélections de l'utilisateur en réponse à la réception par l'utilisateur des résultats de recherche, et le traçage des métadonnées ayant trait aux sélections de l'utilisateur pour les sélections de l'utilisateur qui présentent un niveau-seuil de satisfaction. Ladite méthode comprend en plus le stockage des métadonnées tracées, comme préférences de l'utilisateur et le réglage d'un mécanisme de classement pour augmenter la pondération des préférences de l'utilisateur, afin d'augmenter un classement applicable aux résultats de recherche qui présentent les préférences de l'utilisateur. La méthode proposée comprend en plus le stockage des sélections de l'utilisateur et la recherche de mot-clé, lorsqu'il est déterminé que les sélections de l'utilisateur dépassent un niveau-seuil de satisfaction. Cette méthode peut faire appel aux sélections stockées par l'utilisateur et à la recherche de mot-clé, lors de la réception d'une recherche répétitive, pour modifier la présentation de nouveaux résultats de recherche à l'utilisateur.
Patent CA-2512153-A1 (CA)
Inventor: THOMPSON DELTON R
IPC: G10K11/162
Filed: 2003-11-13
Abstract: Pore plugging is reduced when laminating an airflow resistive membrane to a thermoplastic hot melt adhesive, by treating the membrane to reduce its surface energy. This enables fabrication of acoustical laminates incorporati ng substantial amounts of recycled fibrous insulating mat manufacturing waste, and permits design of the laminate based primarily on one-quarter wavelength sound absorption considerations and control of the porosity and interfacial adhesion of the airflow resistant membrane.
Patent CA-2517141-A1 (CA)
Title: Method to produce a solid form of heparin
Inventor: RAGHAVAN RANGANATHA
IPC: C08J3/14
Filed: 2004-03-04
Abstract: The present invention provides a new method to process a solution containing heparin; heparin salts or heparin complexes in a solvent or a mixture of solvents to a solid form of heparin products characterized by use of a drum dryer at atmospheric pressure or under vacuum and at a suitable drying temperature.
Patent CA-2517554-A1 (CA)
Inventor: HOFACKER STEFFEN
IPC: C08F4/72
Filed: 2005-08-30
Abstract: The present invention relates to a process for preparing oligocarbonate polyols having a number average molecular weight of 500 to 5000 g/mol by reacting organic carbonates and aliphatic polyols in the presence of a metal acetylacetonate catalyst based on a metal which has an atomic number in the PTE of 39, 57, 59 to 69 or 71. The present invention also relates to the oligocarbonate polyols obtained by this process.
Patent CA-2518987-A1 (CA)
Title: Container units for drugs, drug containers, and rubber closures
Inventor: SUDO MORIHIRO
IPC: B65D39/00
Filed: 2005-09-09
Abstract: A container unit for a drug is composed of a container, which is formed of a cylindrical drug-solution-containing portion and a drug-solution-filling neck portion, and a rubber closure for sealing the drug-solution-filling neck portion.      The rubber closure comprises a disk-shaped head portion and a substantially cylindrical leg portion arranged on a lower wall of the head portion. The container is provided with a flat surface formed on a side of its inner wall at a boundary between the drug-solution-containing portion and the drug-solution-filling neck portion such that a lower end wall of the leg portion of the rubber closure can be brought into close contact with the flat surface, and at least a side wall of the drug-solution-containing portion forms a cornerless, rounded surface on a side where a drug solution is to be contained.      When the drug-solution-filling neck portion has been sealed with the rubber closure, the lower end wall of the leg portion and the flat surface of the container are maintained in close contact with each other without any protrusion of an inner circumferential edge of the lower end wall into an interior of the container beyond an inner circumferential edge of the flat surface.
Patent CA-2519266-A1 (CA)
Inventor: XUE GUANGHUI
IPC: A01D7/08
Filed: 2005-09-23
Abstract: The invention provides a garden rake that has the function of a conventional rake as well as a tool to pick up leaves. This invention includes a compound rake, a rake handle and a leaf pick up mechanism. The compound rake consists of two sub rakes that are hinge connected to each other at opposite end of the rakes tine points. The hinge connection allows the two sub rakes to Close and open. The rake handle is tube shaped, allowing a control shaft and a control spring to pass through it. The leaf pick up mechanism includes a connecting rod assembly, a control shaft and a control spring, together with other control elements, the leaf pick up mechanism activates the opening and closing of the compound rake.
Patent CA-2519338-A1 (CA)
Title: Antineoplastic combinations
Inventor: GIBBONS JAMES J JR
IPC: A61K38/21
Filed: 2004-04-14
Abstract: This invention provides the use of a combination of CCI-779 and interferon alfa (.alpha.) in the treatment of neoplasms.
Patent CA-2519753-A1 (CA)
Inventor: BELLS MATTHEW
IPC: G06F3/0481
Filed: 2005-09-14
Abstract: Méthode et appareil pour l'affichage, dans une interface graphique avec fenêtres de visualisation chevauchantes, d'une fenêtre de visualisation de contenu en avant-plan, par-dessus une fenêtre de visualisation de contenu en arrière-plan. La fenêtre de visualisation en avant-plan comporte une zone non transparente qui cache tout ce qui est affiché derrière elle dans la fenêtre de visualisation en arrière-plan, ainsi qu'une zone semi-transparente à travers laquelle le contenu de la fenêtre de visualisation en arrière-plan est partiellement visible.
Patent CA-2523102-A1 (CA)
Inventor: KHANZHIN NIKOLAY
IPC: C07D401/06
Filed: 2004-04-23
Abstract: The present invention relates to aniline derivatives of the general formula I  or pharmaceutically acceptable salts thereof, [Formula (I)], and their use.
Patent CA-2524399-A1 (CA)
Inventor: DESJARLAIS JOHN RUDOLPH
IPC: G16B15/20
Filed: 2004-03-26
Abstract: La présente invention se rapporte à des variants Fc optimisés, à leurs procédés de génération et aux anticorps ainsi qu'aux fusions Fc comprenant des variants Fc optimisés.
Patent CA-2528780-A1 (CA)
Title: Bag sealing system and method
Inventor: TAYLOR MARK W SR
IPC: B65B31/02
Filed: 2004-01-13
Abstract: A system for sealing thermoplastic film includes one or more bag sealing units, each comprising a lower vacuum platen and a vacuum chamber cover adapted for sealing engagement on the platen to form a vacuum chamber. A  sealing bar assembly includes a sealing bar designed for constant heated operation and a pair of cooling plates which function as heat sinks. The sealing bar assembly is pneumatically reciprocated between a raised, disengaged position and a lowered position with the sealing bar engaging the neck of a bag for hermetically sealing same. The cooling plates clamp the bag neck against a sealing support assembly. A method of sealing a thermoplastic film bag includes the steps of placing a packaging object in a thermoplastic bag and placing the bag on a cradle with the bag neck extending over a bag support assembly. A. vacuum chamber cover is placed on the platen and evacuated to form a vacuum chamber. A sealing bar assembly melds the thermoplastic to form a sealed area across the bag neck. A cutoff knife blade severs the end of the bag beyond a sealed area, which extends across its neck.
Patent CA-2529950-A1 (CA)
Title: Spray-dried polymerization catalyst and polymerization processes employing same
Inventor: WAGNER BURKHARD E
IPC: C08F110/02
Filed: 2003-07-16
Abstract: A spray-dried catalyst precursor composition and method of making a spray-dried catalyst precursor composition with an inert filler, magnesium, a transition metal, solvent, and one electron donor compound. The catalyst precursor composition is substantially free of other electron donor compounds, the molar ratio of the electron donor compound to magnesium is less than or equal to 1.9, and comprises spherical or substantially spherical particles having a particle size of from about 10 to about 200 ~m. catalysts made from the spray-dried catalyst precursors and polymerization methods using such catalysts are disclosed.
Patent CA-2530729-A1 (CA)
Inventor: VAN EGMOND JOHN
IPC: B01D35/02
Filed: 2005-12-28
Abstract: A system of deep well barrel debris traps for storm water polishing before discharge to groundwater recharge wells is disclosed herein. The debris trap is formed by one or more traps, which can fill up relatively in sequence. The debris trap captures coarse sediment and leaves which enter into the well portion of wells and aquifer recharge wells. The traps are designed to capture debris and sediment such as leaves, gravel, and other large debris which would plug filters or aquifer formations. By building the traps in series these can capture the entire stream flow, each can fill up individually and when full, can continue to allow substantial flows of water past the individual trap. When used in conjunction with Storm Water Infiltration wells and aquifer recharge wells the debris trap can extent the time between maintenance cycles, increase the time to full cake formation plugging of filters or the aquifer formation.
Patent CA-2531342-A1 (CA)
Title: Methode ne faisant pas appel a des etiquettes pour la classification et pour la caracterisation d'evenements cellulaires
Inventor: VERDONK ED
IPC: G01N27/02
Filed: 2003-07-14
Abstract: L'invention concerne l'utilisation de mesures de bioimpédance de cellules intactes pour classifier et pour caractériser un événement cellulaire global unique quelconque, notamment une transduction de signal à partir d'interactions ligand/récepteur, la cytotoxicité, l'apoptose, la progression cellulaire tumorale ou la différenciation de cellules souches. En particulier, cette invention permet de classifier des trajectoires de transduction de signal à partir de récepteurs nucléaires et d'une tyrosine kinase couplée à une protéine G.
Patent CA-2532231-A1 (CA)
Title: Aminopyrazole compounds and use as chk1 inhibitors
Inventor: ZHU JINJIANG
IPC: A61P35/00
Filed: 2004-07-14
Abstract: Described herein are aminopyrazole compounds of formula (I), wherein R1, R2, L  and Ar are as defined in the specification. Such compounds are capable of modulating the activity of a checkpoint kinase and methods for utilizing such modulation to treat cell proliferative disorders. Also described are pharmaceutical compositions containing such compounds. Also described are the therapeutic or prophylactic use of such compounds and compositions, and methods of treating cancer as well as other diseases associated with unwanted cellular proliferation, by administering effective amounts of such compounds in combination with anti-neoplastic agents.
Patent CA-2535618-A1 (CA)
Inventor: MILWARD FRANCIS WILLIAM
IPC: A61K39/00
Filed: 2004-08-12
Abstract: Combination compositions including C. parvum antigen(s) or epitope(s) of interest with at least one other antigen or epitope of interest from a pathogen that causes enteric infection and/or symptoms and/or recombinant(s) and/or vector(s) and/or plasmid(s) expressing such antigen(s) or epitope(s) of interest and administration of such compositions such as to pregnant mammals and/or newborn or young mammals, for instance, pregnant cows and/or calves such as within the first month of birth, are disclosed and claimed.
Patent CA-2536922-A1 (CA)
Title: Power hand tool right angle attachment having a light source with a self-generating power supply
Inventor: BAKER TIMOTHY
IPC: B23Q5/04
Filed: 2004-08-24
Abstract: A preferred embodiment of the preferred invention comprises a right angle attachment (10) for a power hand tool (20) of the type which has a generally cylindrical elongated housing with a motor contained within the housing or case and the motor having an output shaft that extends from the nose end of the hand tool (20). The attachment (10) has a housing (12) with a mounting end (14) that fits on the nose end portion (22) of the tool housing, with the housing (12) having an input shaft (30) and an output shaft (48) that are operatively coupled together by bevel gears (44, 46) attached to each shaft. A  magnet (74) is mounted on the output shaft (48) near an electric circuit (62, 64, 66, 68, 70) located within the housing (12) for producing current that drives the LED's. Since the magnet (74) and the circuit are inside the housing (12), a lens (70) is provided in the housing (12) adjacent the light producing device (66) for emitting light to the exterior of the housing (12) and toward the tool attached to the distal end (16).
Patent CA-2537246-A1 (CA)
Inventor: MATSUMOTO KUNIO
IPC: A61P43/00
Filed: 2004-08-27
Abstract: A vascularization spur composition, incarnant composition and skin ulcer preventive curative composition, comprising a human recombinant HGF having five amino acid residues deleted in the first Kringle domain thereof. The provided compositions are useful as a drug capable of spurring granulation and vascularization and being effective in tissue restoration, especially as a skin ulcer preventive curative agent.
Patent CA-2538259-A1 (CA)
Inventor: JENKINS DOUGLAS JOHN
IPC: A61K31/445
Filed: 2004-09-24
Abstract: The present invention relates to substituted aryl oximes of formula (I) or a pharmaceutically acceptable salt or ester form thereof wherein R1 is a direct bond to A, C1-C4 alkylene, or -O-C1-C4 alkylene; R2 and R3 are , independently hydrogen, halogen, C1-C4 alkyl, C1-C3 perfluoroalkyl, -O-C1-C3 perfluoroalkyl, C1-C3 alkoxy, -OH, -NH2, -NO2, -O(CH2)p-aryl, -O(CH2)p-heteroaryl, aryl, heteroaryl, -NH(CH2)p-aryl, -NH(CH2)p-heteroaryl, -NH(CO)-aryl, -NH(CO)-heteroaryl, -O(CO)-aryl, -O(CO)-heteroaryl, -NH(CO)-CH=CH-aryl, or -NH(CO)-CH=CH-heteroaryl; p is an integer from 0-6; R4 is hydrogen, C1-C8 alkyl, or C3-C6 cycloalkyl; A is COOH or an acid mimic; X is C1-C8 alkylene, C3-C6 cycloalkylene, -(CH2)mO-, or -(CH2)mNH-; m is an integer from 1-6; R5 and R6 are, independently, hydrogen, halogen, C1-C6 alkyl, C1-C6 perfluoroalkyl, -O-C1-C6 perfluoroalkyl, C1-C6 alkoxy, -OH, -NH2, -NO2, -O(CH2)n-aryl, O(CH2)n-heteroaryl, aryl, or heteroaryl; and is an integer from 0-6, wherein C1-C4 alkaline, -O-C1-C4 alkaline, alkyl, aryl and heteroaryl are each optionally substituted by one or more substituents. The present compounds are PAI-1 inhibitors for the treatment e.g of impairment of the fibrinolytic system, thrombosis or cardiovascular diseases.
Patent CA-2543280-A1 (CA)
Inventor: BENTZ JOHANNA H
IPC: A61K9/70
Filed: 2004-10-21
Abstract: An apparatus for transdermally delivering a biologically active agent to a patient comprising a microprojection member (5) having a plurality of microprojections (10) that are adapted to pierce the stratum corneum of the patient, the microprojection member having a biocompatible coating (16) disposed thereon that includes a biologically active agent selected from the group consisting of peptide and protein conjugates.
Patent CA-2546806-A1 (CA)
Inventor: WRIGHT JEFFREY J
IPC: D06N7/00
Filed: 2004-11-19
Abstract: The present invention pertains to foam cushion backings comprising at least one homogeneously branched ethylene polymer (HBEP) or a substantially linear ethylene polymer (SLEP). More particularly, the present invention pertains to foam cushion backings suitable for use in carpets and carpet tile products.  The present invention further pertains to foam cushion-backed carpet and carpet tile products. The present invention further pertains to methods of making such foam cushion backings and carpet and carpet tiles as described herein.
Patent CA-2546905-A1 (CA)
Title: Silica gel compositions containing alkali metals and alkali metal alloys
Inventor: DYE JAMES L
IPC: C07C17/25
Filed: 2004-11-24
Abstract: The invention relates to Group 1 metal/silica gel compositions comprising silica gel and an alkali metal or an alkali metal alloy. The compositions of the inventions are described as Stage 0, I, II, and III materials. These materials differ in their preparation and chemical reactivity. Each successive stage may be prepared directly using the methods described below or from an earlier stage material. Stage 0 materials may, for example, be prepared using liquid alloys of Na and K which are rapidly absorbed by silica gel (porous Si02) under isothermal conditions, preferably at or just above room temperature, to form loose black powders that retain much of the reducing ability of the parent metals. When the low melting Group 1 metals are absorbed into the silica gel, a mild exothermic reaction produces Stage I material, loose black powders that are indefinitely stable in dry air. Subsequent heating to 400~C produces Stage II materials, which are also loose black powders. Further heating above 400~C forms Stage III material with release of some Group 1 metal. It is believed that Stage I, II and III materials represent reductions of the silica gel after absorption of the Group 1 metal.  Preferred Group 1 metal/silica gel compositions of the invention are those containing sodium, potassium, or sodium-potassium alloys with sodium and sodium- potassium alloys being most preferred. Each stage of the Group 1 metal/silica gel composition of the invention may be used as a reducing agent reacting with a number of reducible organic materials in the same manner known for alkali metals and their alloys.
Patent CA-2547967-A1 (CA)
Inventor: MORISSETTE JOSEE
IPC: A61K48/00
Filed: 1997-04-04
Abstract: The present invention provides delivery systems for delivering ion channel protein genetic material to cardiac cells in areas adjacent to where an electrode is to be positioned in a patient's heart to improve or correct the signal to noise ratio of cardiac signals, such as the P-wave. More specifically, there is provided a system for delivering sodium ion channel proteins or nucleic acid molecules encoding sodium ion channel proteins to a site in the heart adjacent to an electrode to increase the expression of the same, thereby enhancing the cardiac signal amplitude and enabling improved sensing of cardiac signals by an implanted pacemaker.
Patent CA-2551204-A1 (CA)
Inventor: SMITH BRIAN
IPC: A47F3/04
Filed: 2006-06-30
Abstract: A method of refurbishing a cooler display case involving a single step of installing a refurbishing tank cover having a different profile than that of the original equipment manufacturer's (OEM) tank cover and a refurbishing sill cover having a different profile than that of the original equipment manufacturers (OEM) sill over top of existing original equipment manufacturer's (OEM) components which are secured to the cooler display case to cosmetically alter an appearance of the cooler display case. As many OEM  components as possible being left in place to provide underlying support to the refurbishing tank cover and the refurbishing sill cover.
Patent CA-2552310-A1 (CA)
Title: Vacuum container system and related method
Inventor: WALKER CHARLES G
IPC: B01D21/00
Filed: 2005-01-07
Abstract: Apparatus including (a) a substantially rigid container defining at least one inlet port and at least one outlet port, and being sized and configured to define a first volume for receiving a liquid, solid particulate or slurry material; (b) a flexible, substantially non-porous bag which forms a bag opening perimeter in sealed attachment to the container at the inlet port and being in an initial deflated state; and (c) a vacuum pump in fluid communication with the rigid container through said outlet port, wherein during operation of the vacuum pump, a vacuum is created within the rigid container to thereby cause the bag in an initial deflated state to expand and form a vacuum within the bag to draw material through the inlet port and into the bag.
Patent CA-2553918-A1 (CA)
Title: Pharmaceutical composition for promoting angiogenesis
Inventor: MORI TOYOKI
IPC: A61P9/00
Filed: 2005-01-26
Abstract: The present invention provides a pharmaceutical composition for promoting angiogenesis, which has an angiogenesis promoting action even in a vascular culturing system without effect of microcirculation. A pharmaceutical composition for promoting angiogenesis of the present invention comprises at least one compound selected from a group consisting of a piperidine compound represented by the general formula (1) or salts thereof: (wherein R represents a benzoyl group which may have, as substituents on the phenyl ring, 1 to 3 groups selected from a group consisting of an amino group, which may have a lower alkanoyl group, and a lower alkyl group; R1 represents a hydrogen atom or a lower alkyl group; and R2 represents a phenyl lower alkyl group).
Patent CA-2557096-A1 (CA)
Title: Floor panel
Inventor: EISERMANN RALF
IPC: E04F15/00
Filed: 2005-01-06
Abstract: The invention relates to a floor panel (1, 2) comprising a carrier plate (3, 4) to which a useful layer (5, 6) provided with a decorative image divided into various sections is applied, said decorative image being protected from wear by abrasionproof particles. The surface of the useful layer has a relief of recesses and raised parts. The recesses comprising certain image sections of the decorative image are surrounded by the raised parts comprising other image sections of the decorative image, said decorative image being coated with a transparent layer of lacquer. According to the invention, the recesses of the relief are produced by a chemical reacting with the lacquer, and the abrasionproof particles are contained in the layer of lacquer.