baber/WOPTO huggingface dataset:
Patent CA-3111518-A1 (CA)
Inventor: QUIJANO ELIAS
IPC: A61K48/00
Filed: 2019-08-30
Abstract: Compositions for enhanced gene editing and methods of use thereof are. The composition contains a cell-penetrating antibody and a donor oligonucleotide containing a sequence that can correct a mutation in a cell's genome. Preferably, the composition does not contain a nuclease, PNA, or nanoparticle. The compositions are used to modify the genome of a cell by contacting the cell with an effective amount of the composition. Genomic modification occurs at a higher frequency both ex vivo and in vivo, when cells are contacted with the cell-penetrating antibody and donor oligonucleotide as compared to the absence of the cell-penetrating antibody.
Patent CA-3114087-A1 (CA)
Title: Face mask system with condition indicator
Inventor: KERSEY ALAN
IPC: A41D13/11
Filed: 2021-04-06
Abstract: A face mask system is provided that includes a face mask and an indicator. The indicator is arranged with the face mask. The indicator may be configured to indicate the face mask is no longer recommended for use following a first level of exposure of the face mask to ultraviolet light. In addition, or alternatively, the indicator may be configured to change its appearance when a first number of treatment cycles have been performed on the face mask using the ultraviolet light. In addition, or alternatively still, the indicator may be configured to visually indicate a mechanical property of the face mask is preserved following another level of exposure of the face mask to the ultraviolet light.
Patent CA-3114465-A1 (CA)
Title: Next-generation sequencing-based method for detection of microsatellites stability and genomic changes in plasma samples
Inventor: HAN YUSHENG
IPC: G16B30/00
Filed: 2019-09-29
Abstract: On the one hand, disclosed in the present invention are a biomarker combination, a kit for detecting same, and use thereof in microsatellite instability (MSI) detection in a plasma sample, non-invasive diagnosis for cancers, preferably rectal cancer (such as intestinal cancer), gastric cancer and endometrial cancer, prognosis evaluation, and selection of treatment regimens or genetic screening. On the other hand, the present invention provides a second generation sequencing-based method for detecting microsatellite instability (MSI) and disease-related genetic mutation by means of plasma, a device for implementing the method, and particularly the use of the detection method in non-invasive diagnosis for cancers, preferably rectal cancer (such as intestinal cancer), gastric cancer and endometrial cancer, prognosis evaluation, and selection of treatment regimens or genetic screening. The present application first provides a plasma MSI detection method, which is capable of determining the microsatellite (MS) state of a sample with high accuracy and sensitivity.
Patent CA-3116140-A1 (CA)
Inventor: TECHLIN MICHAEL E
IPC: B65H19/10
Filed: 2019-05-20
Abstract: A core end engagement assembly is proivded for a rewinding machine. The core end engagement assembly is configured to engage an end of the core and transmit rotational movement to the core during winding of the web material about the core. The assembly may include a drive housing. A chuck may project from a first end of the drive housing and may be configured to engage the end of the core. A first actuator may reciprocate the drive housing along a central axis of the core between an engagement and disengagement position of the chuck relative to the core. A second actuator may be mounted on the drive housing. The second actuator may be configured and adapted to move the chuck between release and hold positions. A flexible drive shaft operatively connects with and rotationally drives the chuck.
Patent CA-3118928-A1 (CA)
Inventor: EVULET ANDREI
IPC: F02K1/36
Filed: 2019-11-11
Abstract: A propulsion system for an aircraft includes a plenum having an intake port and an output port. A fan is coupled to a motor configured to power the fan, and the powered fan is configured to compress ambient air entering the intake port. One or more ejectors are fluidically coupled to the plenum via one or more valves. A nozzle is disposed within the output port and includes a set of vanes. The system operates in a first configuration in which the nozzle vanes are closed and the compressed ambient air exits the plenum only through the one or more valves into the one or more ejectors. The system operates in a second configuration in which the one or more valves are closed, the nozzle vanes are open and the compressed ambient air exits the plenum only through the output port.
Patent CA-3119015-A1 (CA)
Title: Carrier based laser assembly and method of assembly thereof with photonic integrated circuit
Inventor: HICKEY RYAN MURRAY
IPC: H01S5/02375
Filed: 2021-05-18
Abstract: A carrier laser device assembly is provided in which a visible region of a laser that includes an output portion and/or output portion of a waveguide of the laser is visible to an irnaging system when the laser is attached to a carrier. The laser may be burned-in and/or tested prior to attachrnent to a photonic integrated circuit. The output portion and/or output portion of waveguide may be aligned with a corresponding input portion and/or input portion of a waveguide of the PIC as the laser assernbly is being attached to the PIC via irnaging of the visible portion by the imaging system.
Patent CA-3121698-A1 (CA)
Title: Lightweight asymmetric magnet arrays with theta magnet rings
Inventor: HAHAM HAY NOAM
IPC: H01F7/02
Filed: 2019-11-10
Abstract: A magnet array (700) includes multiple magnet rings (711-720) and a frame. The multiple magnet rings are positioned along a longitudinal axis and coaxially with the longitudinal axis, wherein at least one (712, 713, 719) of the magnet rings possesses rotational symmetry and has both a finite component of magnetization along an azimuthal (?) coordinate, and a finite magnetization in a longitudinal-radial plane. The multiple magnet rings configured to jointly generate a magnetic field along a direction parallel to the longitudinal axis. The frame is configured to fixedly hold the multiple magnet rings in place.
Patent CA-3122949-A1 (CA)
Inventor: JEONG CHANYOUNG
IPC: C09K13/04
Filed: 2019-11-08
Abstract: La présente invention concerne un procédé pour la fabrication d'un film anodisé d'alliage d'aluminium ayant une surface super-hydrophobe et un alliage d'aluminium ayant un film anodisé doté d'une surface super-hydrophobe fabriqué par le procédé. La présente invention a un effet économique consistant en ce qu'un alliage d'aluminium, sur la surface duquel est formée une structure de film anodisé de forme tridimensionnelle qui est mise sous diverses formes voulues, telle qu'une structure de piliers-sur-pores, peut être fabriqué à faible coût sur une courte durée. L'alliage d'aluminium portant la structure de film anodisé voulue a un excellent caractère super-hydrophobe, une excellente résistance à la corrosion et une excellente conductivité thermique et peut ainsi être utilisé dans divers domaines industriels, tels que des boîtiers de dispositifs électroniques, des couvercles d'éclairages à DEL, des échangeurs de chaleur, des tuyaux, des structures de route, des automobiles, des aéronefs, des navires et des générateurs.
Patent CA-3124470-A1 (CA)
Title: Gain and loss computation for cryptocurrency transactions
Inventor: SHTEYNBERG VADIM
IPC: G06Q40/00
Filed: 2019-12-19
Abstract: A method for gain and loss computation for cryptocurrency transactions comprises: identifying a plurality of cryptocurrency trading transactions associated with an accounting perimeter of a plurality of accounting perimeters associated with one or more cryptocurrency trading accounts, wherein each cryptocurrency trading transaction of the plurality of cryptocurrency trading transactions is represented by one of: a cryptocurrency acquisition transaction or a cryptocurrency disposal transaction; for a given transaction perimeter, assigning each cryptocurrency trading transaction associated with the transaction perimeter to a transaction bucket of the sequence of transaction buckets associated with the transaction perimeter, wherein the transaction bucket is identified by a start time and an end time, and wherein the transaction bucket is selected based on a timestamp of the cryptocurrency trading transaction, such that the timestamp falls between the start time and the end time; and for a given transaction bucket, matching each cryptocurrency disposal transaction.
Patent CA-3127124-A1 (CA)
Title: Method and system for desalinating a saltwater using a humidifier unit
Inventor: SPARROW BENJAMIN
IPC: C02F1/02
Filed: 2020-01-22
Abstract: Methods, systems, and techniques for desalinating a saltwater using a humidifier unit. The humidifier unit has a housing, which has a carrier gas inlet and a saltwater inlet. The humidifier unit also includes a packing, within the housing, having a surface with a critical surface tension of less than 25 mN/m according to the Zisman method. The packing is arranged to facilitate a saltwater that enters the housing through the saltwater inlet and a carrier gas that enters the housing through the carrier gas inlet to contact each other. The contact facilitates evaporation of the saltwater, which produces salt solids on at least a surface of the packing, a humidified gas and a concentrated brine.
Patent CA-3129775-A1 (CA)
Title: Collapsible article comprising a plurality of foldably interconnected foldable sections
Inventor: ZAHARINOV PETAR
IPC: B65D3/04
Filed: 2018-10-17
Abstract: Collapsible article cornprising a plurality of foldably interconnected foldable sections/modules. The foldable sections can be part of cylindrical or conical surfaces. They can also be in the form of closing sections. When the foldable sections are part of tubular surfaces, either cylindrical or conical, they consist of four polygonal surface segments. The polygonal segments are curved/round in unfolded state and have a flat or approxirnately flat shape in partly folded and folded states. The folding process usually involves an abrupt transition between the unfolded and folded positions which makes the unfolded article alrnost as stable as non-foldable equivalents. In general, the folding process requires application of force on the edges that form valley creases during folding. When the article is rnade of soft materials or has a constant or relatively constant thickness with convex and/or concave foldable edges it usually collapses when excessive axial force is applied.
Patent CA-3130774-A1 (CA)
Title: Internet of things lock module
Inventor: KINCAID RYAN C
IPC: G08B19/00
Filed: 2020-02-18
Abstract: An exemplary Internet of Things (IoT) module for a lockset includes a housing assembly configured for mounting with the lockset, a controller, a wireless transceiver, and a sensor array, and may further include an LED array. The controller is in communication with an external device via the wireless transceiver, and is configured to transmit to the external device information received from the sensor array. The controller is further configured to control operation of the LED array based on information received from at least one of the sensor array or the external device.
Patent CA-3132628-A1 (CA)
Inventor: LUKE GEORGE
IPC: A61K31/4545
Filed: 2020-03-13
Abstract: La présente invention concerne des formes solides et salines d'inhibiteurs de la famille CBP/p300 de bromodomaines constitués de sels et de formes cristallines de formule (I). Les composés peuvent être utiles dans le traitement de maladies ou de troubles associés à l'inhibition de la famille CBP/p300 de bromodomaines. Par exemple, l'invention concerne des composés et des compositions pour l'inhibition de la famille CBP/p300 de bromodomaines, des procédés de traitement de maladies ou de troubles associés à l'inhibition de la famille CBP/p300 de bromodomaines (par exemple, certaines formes de cancer), et des procédés de synthèse de ces composés.
Patent CA-3135319-A1 (CA)
Inventor: XU HAIBO
IPC: H04W24/02
Filed: 2020-03-30
Abstract: Provided are a radio bearer configuration method, apparatus and system, which relate to the technical field of communications and are used for improving the reliability of a sidelink service. The method comprises: a second terminal determining that a first sidelink radio bearer used when the second terminal communicates with a first terminal is associated with a second sidelink radio bearer; and the second terminal sending a first message to the first terminal, wherein the first message comprises first indication information, the first indication information is used for indicating that the first sidelink radio bearer is associated with the second sidelink radio bearer, the first sidelink radio bearer is used for the first terminal to send first sidelink service data to the second terminal, and the second sidelink radio bearer is used for the second terminal to send, to the first terminal, a first radio link control (RLC) state report with regard to the first sidelink service data.
Patent CA-3138473-A1 (CA)
Inventor: SCHAFER PETER HENRY
IPC: A61P19/02
Filed: 2019-04-30
Abstract: L'invention concerne des méthodes de traitement de maladies et de troubles sensibles à l'inhibition de PDE4 qui consistent à administrer de l'aprémilast et un inhibiteur de Tyk2 à un sujet. L'invention concerne également des compositions pharmaceutiques comprenant de l'aprémilast et un inhibiteur de Tyk2.
Patent CA-3138515-A1 (CA)
Inventor: SCHLEDER NICHOLAS
IPC: G02F1/163
Filed: 2020-04-29
Abstract: Dans la présente invention, une réponse électrique d'une structure de vitrage teintée à une impulsion de détection électrique appliquée peut être mesurée et un ou plusieurs paramètres de la structure de vitrage teintée peuvent être caractérisés. Le paramètre ou les paramètres peuvent être utilisés pour charger un ou plusieurs paramètres d'entraînement pour une utilisation ultérieure dans un signal d'entraînement électrique utilisé pour faire fonctionner la structure de vitrage teintée. Si un signal d'entraînement électrique est déjà en place, le paramètre ou les paramètres caractérisés peuvent être comparés à un ou plusieurs paramètres caractérisés à un moment précédent. Si le paramètre ou les paramètres caractérisés sont différents de ceux qui furent caractérisés au moment précédent par plus d'une quantité seuil, un ou plusieurs paramètres d'entraînement du signal d'entraînement électrique peuvent être ajustés sur une nouvelle valeur.
Patent CA-3139095-A1 (CA)
Title: Implantable apparatus for sensing biologic signals
Inventor: KOWARZ MAREK
IPC: A61B5/00
Filed: 2020-05-06
Abstract: An implantable apparatus for physiological measurement in a host organism has an implantable sample chamber having a measurement port and live ceils that are treated to fluoresce in response to light having an excitation wavelength. An optical sensor housing implanted within the host organism has a window' to convey excitation light output and receive fluorescent light; a coupling that couples the measurement port of the sample chamber to the window; an optical chamber partitioned into an excitation sub-chamber and a detection sub-chamber, wherein both sub-chambers are in optical communication with the window; an excitation source energizable to direct excitation light through the excitation sub- chamber and to the window; and a detector in the path of fluorescent light received from the live cells. A signal processing apparatus is energizable to acquire and process a detector signal and to transmit a processed signal that is indicative of fluorescent light energy.
Patent CA-3142807-A1 (CA)
Inventor: KRYWYJ DANIEL MILNE
IPC: G01F1/68
Filed: 2020-06-04
Abstract: L'invention concerne des procédés, des systèmes et des appareils pour détecter et déterminer des états d'une conduite de fluide et des états à l'intérieur de celle-ci.
Patent CA-3143895-A1 (CA)
Inventor: NOBLE ADAM J
IPC: C12M1/04
Filed: 2020-06-29
Abstract: Des modes de réalisation de l'invention concernent des procédés, des systèmes et des bioréacteurs pour la culture d'un micro-organisme de l'espèce Euglena, d'un micro-organisme de l'espèce Schizochytrium, ou d'un micro-organisme de l'espèce Chlorella, consistant à : mettre en culture le micro-organisme dans un milieu de culture contenant une ou plusieurs sources de carbone, une ou plusieurs sources d'azote et un ou plusieurs sels; maintenir un pH compris entre environ 2,0 et environ 4,0; maintenir une température entre environ 20 °C et environ 30 °C; et maintenir un environnement sensiblement dépourvu de lumière; la mise en culture se produisant en trois étapes de culture.
Patent CA-3145764-A1 (CA)
Title: Flame-resistant composites for roofing underlayment
Inventor: CARR JOSEPH R
IPC: B32B11/02
Filed: 2020-07-02
Abstract: A composite comprising (i) a pressure-sensitive adhesive component including first and second planar surfaces; (ii) a fire-resistant fabric adhered to the first planar surface; and (iii) a cap layer disposed on said fire-resistant fabric opposite said asphaltic component.
Patent CA-3145961-A1 (CA)
Title: Fracture fixation plate for application to the proximal humerus
Inventor: SCHALLBERGER ALEX
IPC: A61B17/80
Filed: 2019-07-11
Abstract: The invention relates to a fracture fixation plate (1) suitable for application to the proximal humerus, wherein  a) the fracture fixation plate (1) has an elongate body section (2) which has a free distal end (3) and a proximal end (4) to which there are adjoined, one on each side, a right wing (5) having the centre line (11) and a left wing (6) having the centre line (12);  b) the body section (2) and the two wings (5, 6) are provided with a number of screw holes (7) for receiving bone-fastening elements (8), and the fracture fixation plate (1) has a bone contact face (9) and an opposite surface (10), and  c) the two wings (5, 6) have different lengths. Furthermore,  d) the two wings (5, 6) are bent; and  e) the extensions of the two bent centre lines (11, 12) form an obtuse angle a.
Patent CA-3147196-A1 (CA)
Title: Method for and apparatus for decoding an ambisonics audio soundfield representation for audio playback using 2d setups
Inventor: KEILER FLORIAN
IPC: H04S3/00
Filed: 2014-10-20
Abstract: Sound scenes in 3D can be synthesized or captured as a natural sound field. For decoding, a decode matrix is required that is specific for a given loudspeaker setup and is generated using the known loudspeaker positions. However, some source directions are attenuated for 2D loudspeaker setups like e.g. 5.1 surround. An improved method for decoding an encoded audio signal in soundfield format for L loudspeakers at known positions comprises steps of adding (10) a position of at least one virtual loudspeaker to the positions of the L loudspeakers, generating (11) a 3D decode matrix (DI wherein the positions (Formula l) of the L loudspeakers and the at least one virtual position (Formula II) are used, downmixing (12) the 3D decode matrix (DI and decoding (14) the encoded audio signal (i14) using the downscaled 3D decode matrix (Formula III). As a result, a plurality of decoded loudspeaker signals (q14) is obtained.
Patent CA-3147227-A1 (CA)
Title: Interfering radio and vehicle key locker
Inventor: LEE JASON
IPC: B60R25/24
Filed: 2020-07-30
Abstract: A jamming radio signal is outputted to interfere with an interrogation signal emitted by a vehicle for verifying a tag of a vehicle key that provides access to the vehicle. An access signal including access data is received. The output of the jamming radio signal is halted, at least temporarily, when the access data matches an access code so that the tag of the vehicle key can be authenticated.
Patent CA-3147885-A1 (CA)
Inventor: ZOELLNER SASCHA KRISTOPHER
IPC: A61M16/06
Filed: 2020-07-20
Abstract: A cushion module for a patient interface is disclosed. The cushion module comprising a first cavity, a second cavity, a nasal aperture and an oral aperture. The first and second cavities are separated by a cavity wall that enables respiratory gas to flow within the cushion module between the first and second cavities when in use. Additionally, the first cavity is configured to communicate respiratory gas to both the mouth and the nares of a patient via the oral aperture and the nasal aperture respectively. The cushion module comprises an exhaust vent to communicate respiratory gas from within the cushion module to externally of the cushion module and the second cavity is in communication with the exhaust vent. Also disclosed are a cavity wall and a cushion module.
Patent CA-3152546-A1 (CA)
Inventor: POUILLOT FLAVIE
IPC: A01N63/40
Filed: 2015-01-09
Abstract: The present invention relates to bacteriophage therapy. More particularly, the present invention relates to novel bacteriophages having a high specificity against Escherichia colis trains, their manufacture, components thereof, compositions comprising the same and the uses thereof in phage therapy.
Patent CA-3152576-A1 (CA)
Inventor: MCCURRY RONALD C
IPC: B23D45/16
Filed: 2021-04-23
Abstract: A compact multi-material cut-off tool includes a housing, and an arbor rotatably supported by the housing upon which a cutting disk is attachable for co- rotation therewith. A motor is coupled to the arbor to provide torque thereto. A controller is operable to selectively drive the motor in a first rotational direction and an opposite, second rotational direction. A first lighting element is coupled to a first portion of the housing, and a second lighting element is coupled to a second portion of the housing. One of the first lighting element and the second lighting element is configured to be activated by the controller in response to the motor being driven in the first rotational direction. The other of the first lighting element and the second lighting element is configured to be activated by the controller in response to the motor being driven in the second rotational direction.
Patent CA-3153699-A1 (CA)
Title: Energy management system and methods
Inventor: MADONNA ROBERT P
IPC: H02J3/32
Filed: 2020-09-11
Abstract: An energy management system interoperates with an automation system to provide integrated control over essentially all power-consuming, power-generating, and power storage devices in a home or other environment. The energy management system provides configurable energy management scenes in which one or more values, each representing a desired operating condition, are associated with some or all of the loads of a home, business or other environment. Different energy management scenes may be configured for different environmental conditions including season, day of week, time of day, grid status, battery condition, and generator condition among others.
Patent CA-3156013-A1 (CA)
Inventor: ZHOU YONGJI
IPC: F16H55/16
Filed: 2020-09-25
Abstract: La présente invention concerne une roue dentée améliorée permettant l'engrènement amélioré de roues dentées lorsqu'elles fonctionnent perpendiculairement. En termes généraux, l'invention introduit une conception en roue dentée multiple ayant des dimensions et des profils de dent spécifiques afin de permettre une mise en prise perpendiculaire de roues dentées tout en permettant la translation de telles roues dentées. À cet effet, la présente invention concerne une roue dentée comprenant une première partie de roue dentée comprenant une pluralité de dents et une seconde partie de roue dentée comprenant un même nombre de dents que la première partie de roue dentée. La seconde partie de roue dentée est disposée axialement à distance de la première partie de roue dentée, la seconde partie de roue dentée a sensiblement le même pas circulaire que la première partie de roue dentée, chaque dent de la seconde partie de roue dentée est décalée dans une direction de rotation de l'ordre de la moitié du pas circulaire par rapport à la première partie de roue dentée, une largeur de face de la première partie de roue dentée est sensiblement équivalente à la moitié du pas circulaire de la première partie de roue dentée, et une largeur de face de la seconde partie de roue dentée est sensiblement équivalente à la moitié du pas circulaire de la seconde partie de roue dentée.