baber/WOPTO huggingface dataset:
Patent CA-2500932-A1 (CA)
Title: Methods for substrate and modulator screening using enzyme-reactor, chromatography/tandem mass spectrometry
Inventor: BESANGER TRAVIS
IPC: C12Q1/26
Filed: 2005-03-15
Abstract: The present invention relates to a method of screening compounds for modulation and binding to proteins, in particular proteins that have been immobilized in a monolithic chromatographic stationary phase. The method involves observing the conversion of a substrate to product by the protein and determining a product to substrate ratio. Changes in this ratio in the presence of another compound indicates that the other compound is a modulator of the enzyme. Various applications of this method to compound screening, including high throughput screening formats, are described.
Patent CA-2501780-A1 (CA)
Inventor: COSTANTINI ANNE
IPC: A01K11/00
Filed: 2003-10-14
Abstract: The programmable transponder has a central axial passage (4) fixed to the animal ear. The body is made in two halves, a lower (1) and upper (2) part. The transponder (3) is held without compression between the two halves by a collar (17). The two halves are assembled by laser soldering.
Patent CA-2505994-A1 (CA)
Title: Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasis
Inventor: LONG LI
IPC: G01N33/574
Filed: 2003-11-17
Abstract: M-CSF antagonists are provided, along with pharmaceutical compositions containing a M-CSF antagonist, kits containing a pharmaceutical composition, methods of preventing and treating bone metastases in a subject afflicted wi th metastatic cancer, methods of screening for M-CSF antagonists, and uses of M - CSF in medicine and preparing medicaments for preventing and treating bone metastases and tumor growth.
Patent CA-2506113-A1 (CA)
Title: Method and apparatus for cleaning a turbofan gas turbine engine
Inventor: HJERPE CARL-JOHAN
IPC: B08B9/00
Filed: 2004-02-16
Abstract: Device for cleaning a gas turbine engine (2), and in particular an engine of turbofan type. The present invention further relates to a method for cleaning such a engine. The device comprises a plurality of nozzles (31, 33, 35) arranged to atomize cleaning liquid in the air stream in an air inlet (20) of the engine (2) up-stream of a fan (25) of the engine (2). According to the invention a first nozzle (31) is arranged at a position such that the cleaning liquid emanating from the first nozzle (31) impinges the surfaces of the blades (40) substantially on the pressure side (53); a second nozzle (35) is arranged at a position such that the cleaning liquid emanating from the second nozzle (35) impinges the surfaces of the blades (40) substantially on the suction side (54); and a third nozzle (33) is arranged at a position such that the cleaning liquid emanating from the third nozzle (33) passes substantially between the blades (40) and enters an inlet (23) of the core engine (203). Thereby, the different types of fouling found on the fan and in the core engine compressor of turbofan engine can be removed in an efficient manner.
Patent CA-2506653-A1 (CA)
Title: Bone screw
Inventor: FRENK ANDRE
IPC: A61B17/86
Filed: 2001-12-04
Abstract: Bone screw including two threaded segments (5;7) formed axially in the end portions thereof and an intermediate segment (6), the outside diameter D VS of the threaded front segment (5) being smaller than the core diameter D KH of the threaded rear segment (7) and the outside diameter D MS of the intermediate segment (6) being smaller than the core diameter D KV of the threaded front segment (5).     Device for the reduction, compression, and fixation of bone fragments, comprising a) an implantation instrument (15) comprising a central bore (17) extending coaxially therethrough, so that b) a screwdriver (16) may be passed through said central bore (17) from the rear end (19) of the instrument (15), c) the central bore (17) being provided with an internal screw thread (20) formed in the front end portion (18) of the instrument (15), which is complementary to the external screw thread (9) formed in the threaded rear segment (7) of the bone screw (1) and which extends from the front end portion (18) of the implantation instrument (15) to a depth T; and e) the depth T is >= L, L being the length of the threaded rear segment (7) of the bone screw (1).
Patent CA-2507331-A1 (CA)
Inventor: BUROW WILFRIED
IPC: C09C1/24
Filed: 2005-05-13
Abstract: The present invention relates to pure-coloured, readily dispersible iron oxide red pigments having high grinding stability, to a process for preparing them, and to their use.
Patent CA-2508685-A1 (CA)
Title: Self-centering device for compensation ropes or chains of an elevator
Inventor: OGAVA MARIO
IPC: B66B7/10
Filed: 2005-05-27
Abstract: Elevator comprising a cabin (2) with a cabin floor (10) and at least a compensation chain or rope (6) being connected by a fixation point to the cabin floor, wherein a displacement element (4) is provided to displace said fixation point in dependence on the weight force and torque applied by the compensation chain or rope to the cabin floor.
Patent CA-2510379-A1 (CA)
Title: Apparatus for forming a spliced yarn
Inventor: WHITLEY MARK JEFFERSON
IPC: B65H69/06
Filed: 2003-12-12
Abstract: Apparatus for forming a spliced yarn includes a yarn conduction member with an intermingling jet disposed forwardly thereof. The yarn conduction member has respective yarn conduction channels through which the first and second yarns are conveyed to the intermingling jet. The axis of each yarn conduction channel from the inlet to the outlet of the member is a straight line, with no bends or deviations. The yarn conduction member has a knife blade disposed adjacent to a respective yarn conduction channel. Each knife blade has a passage defining a cutting edge and a solid portion disposed between the passage and the tip of the blade. The first and second knives are insertable into and retractable from the channel to which they are adjacent. In the inserted position the passage in the knife aligns with the channel into whic h it is inserted, while in the retracted position the solid portion of the bla de interdicts the passage to prevent movement of a yarn therethrough.
Patent CA-2511202-A1 (CA)
Title: Cyclopentil-substituted glutaramide compounds as endopeptidase inhibitors
Inventor: DACK KEVIN NEIL
IPC: C07D213/30
Filed: 2003-12-10
Abstract: The invention relates to NEP inhibitors for treating cardiovascular disorders.  Preferred NEP inhibitors are compounds of formula (I) wherein R1 is C,-C6alkyl, Ci-C6alkoxyC,~C3alkyl or C,-C6alkoxyC,-C6alkoxyC,-C3alkyl; R2 is hydrogen or C,-C6alkyl; L is a three 5 atom linkage selected from -CH2-X-CH2-and -CH2-CH2-X- where the right hand side of the linkage is attached to R3 and where X is oxygen, sulfur or methylene; R3 is phenyl or aromatic heterocyclyl, either of which may be independently substituted by one or more groups selected from: C1-C6alkyl, halo, haloC,-C6alkyl, C,-C6alkoxy, haloC1-C6alkoxy, C1-~C6alkylthio, haloC,-C6alkylthio and nitrile; and R4 and R5 are either both hydrogen, or one of R4 and R5 is hydrogen and the other is a biolabile ester-forming group that in the body of a patient is replaced by hydrogen.
Patent CA-2511701-A1 (CA)
Title: Conveyor apparatus
Inventor: HESS MICHAEL
IPC: B01D21/00
Filed: 2005-07-08
Abstract: Conveyor apparatus for conveying solid material in a process vessel (66) including, a first baffle set (4) comprising a plurality of inclined baffles (6) located above the eductors and arranged to restrict upward flow of solids in the direction of the said movement of the solids. A second baffle set (10) may be used to prevent particles rebounding from the end wall and back into the upper levels of the vessel (66).
Patent CA-2512177-A1 (CA)
Title: Recliner assembly for an automotive vehicle seat having a floating cam
Inventor: TAME OMAR D
IPC: B60N2/235
Filed: 2004-01-26
Abstract: A recliner assembly is disclosed for providing selective pivotal adjustment of a seat back (14) relative to a seat cushion (12) . The recliner assembly includes a fixed plate (30) fixedly secured to the seat cushion and a mobile plate (30) fixedly secured to the seat back. The mobile plate is fixedly secured to the fixed plate. The mobile plate includes an annular rim having a plurality of teeth (62) . A pawl is slidably supported between the fixed and mobile plates for movement in and out of locking engagement with the plurality of teeth. A cam (70) is fixedly secured to a shaft (60) rotatably journaled through an aperture (36) formed in the mobile plate. The aperture is oversized relative to the shaft to allow the shaft and the cam to float radially relative to the pawl to help prevent binding of the pawl during movement in and out of locking engagement with the plurality of teeth.
Patent CA-2515192-A1 (CA)
Inventor: ALLEN SHELLEY JANE
IPC: C12N5/079
Filed: 2004-02-12
Abstract: A biocompatible, biodegradable composition for encouraging controlled growth, regeneration or repair of biological tissue or cells, the composition comprising a scaffold, formed from biodegradable and biocompatible material, and a receptor for a growth factor, or a growth factor-binding fragment or homologue thereof, located at or adjacent a surface of the scaffold. The tissue or cells are preferably neuronal, in which case the receptor is preferably a tyrosine receptor kinase (Trk), or a neurotrophin-binding fragment or homologue thereof. Such a composition may include one or more types of neurotrophin bound to the Trk or fragment or homologue thereof.
Patent CA-2516179-A1 (CA)
Title: Method and apparatus for visually indexing objects upon a moving surface
Inventor: BLAINE GEORGE
IPC: B26D5/00
Filed: 2004-02-09
Abstract: A visual indexing system (10) for assisting placement of an object (36) in a selected location upon a surface (16) moving in a selected direction at a selected speed relative to a stationary frame is provided. The indexing system includes a visual image generator (12) operable to project a visual image (18) upon the moving surface such that the visual image is reproduced upon the moving surface. The indexing system also includes a controller (14) adapted to control the location at which the visual image generator projects the reproduced visual image (18) upon the moving surface. The controller controls the location of the reproduced visual image such that the reproduced visual image moves in substantially the same selected direction and speed as the moving surface, thereby resulting in substantially no relative movement between the reproduced visual image and the moving surface.
Patent CA-2517666-A1 (CA)
Title: Angled dual check valve
Inventor: DUEX KARL D
IPC: E03B7/07
Filed: 2005-08-31
Abstract: Poppet valve installation or removal is simplified through the use of a unitary poppet assembly that may be accurately placed into a valve body through an access opening and wherein the poppet is slidably mounted in a stem in an insert while being permanently affixed thereto by the interference fit between a shoulder on the poppet stem and a post within the sleeve.
Patent CA-2518452-A1 (CA)
Title: Reca-assisted allele specific oligonucleotide extension method for detecting mutations, snps and specific sequences
Inventor: WAGNER ROBERT E
IPC: C12Q1/68
Filed: 2004-03-05
Abstract: A method for detecting a specific sequence, a mutation and/or a polymorphisms, including a SNP, is based on the use RecA or a RecA-like recombinase protein and the process of allele specific oligonucleotide extension. RecA coated, specific DNA oligonucleotide probes (RecA filaments) are used for homology searching in duplex DNA. Location of homologous sequences results in the formation of D-loop or double D-loop structures containing a duplex regions comprising the oligonucleotide probe and one strand of the target DNA. Probes are selected to terminate with their 3' end at the site of the mutation or the SNP, such that extension depends on correct nucleotide pairing, which occurs only when the probe is annealed to a target DNA which comprises the allele complementary to the 3' end of the probe. Successful extension is diagnostic of the specific sequence, mutation or SNP. Also provided are compositions and kits useful for practicing the above methods.
Patent CA-2520425-A1 (CA)
Title: Production of 5-methyl-n-aryl-2-pyrrolidone and 5-methyl-n-cycloalkyl-2-pyrrolidone by reductive amination of levulinic acid with aryl amines
Inventor: MANZER LEO ERNEST
IPC: C07D207/267
Filed: 2004-03-23
Abstract: This invention relates to a process for producing 5-methyl-N-aryl-2-pyrrolidone and 5-methyl-N-cycloalkyl-2-pyrrolidone by reductive amination of levulinic acid or its derivatives with aryl amines, ammonia or ammonium hydroxide utilizing a metal catalyst, which is optionally supported.
Patent CA-2520466-A1 (CA)
Inventor: ENGDAHL GERALD E
IPC: F24H9/18
Filed: 2005-09-27
Abstract: A submerged combustion apparatus and method for heating large quantities of water and other fluids in many applications has water to be heated exiting an orifice opening and flowing across a perforated plate, where the water is heated by products of combustion passing through apertures in the perforated plate. The low submergence, low backpressure heat and mass transfer arrangement provides an effective and efficient system for heating water and other fluids and concentrating water solutions.
Patent CA-2520678-A1 (CA)
Title: System and method for manufacturing welded structures, and a welding additive material for this purpose
Inventor: HACKIUS JENS
IPC: B23K26/20
Filed: 2005-09-22
Abstract: A system for manufacturing welded structures comprises components to be welded, a welding additive material which, before the welding, is to be positioned at a location at which the components are to be welded to one another and which is tailored to the construction of at least one of the components. Furthermore, at least one heat source is provided which treats the welding additive material in such way that the components are welded to one another.
Patent CA-2523190-A1 (CA)
Inventor: KNIERIEME RALF
IPC: C07D213/56
Filed: 2004-03-27
Abstract: L'invention concerne un procédé pour produire des aldéhydes de nicotine par réduction des amides de morpholine de l'acide nicotinique correspondants.
Patent CA-2523902-A1 (CA)
Title: Container with hinged lids and method of molding the container and assembling the hinged lids on the container in the molding process
Inventor: MILLER DANIEL R
IPC: B29C65/58
Filed: 2005-10-21
Abstract: An attached lid container has lids that are hinged to the top edges of the side walls of the container. When the lids are closed, the free edges of the lids engage one another to form a joint that interlocks the lids together. The lids are attached to the container at the hinge joints after the molding of the container and lids, while the molded parts are still in the mold press. Specifically, the lids are molded next to the container and then moved laterally to be aligned with the hinge line of the container after the mold cavity is withdrawn. Then, the ejectors push the lids out toward the container. The force of the outward movement causes the hinge parts of the lids and container to snap together. Subsequently a robot arm removes the container from the mold press with the hinged lids assembled on the container.
Patent CA-2526296-A1 (CA)
Title: Vecteur navette et usage dans l'evaluation de phenomene de mutation
Inventor: ROUGEON FRANCOIS
IPC: C12N5/10
Filed: 2005-11-18
Abstract: La présente invention concerne une construction d'ADN, telle un vecteur navette, utile dans des méthodes de détection et/ou d'évaluation quantitativ e ou qualitative d'un phénomène de mutation, comme par exemple ceux intervenant au cour d'une hypermutation somatique, d'une cellule ou d'un groupe de cellules. Ce vecteur navette est également utile dans une méthode de diagnostic et/ou de pronostic d'évolution d'une maladie hématologique.
Patent CA-2527036-A1 (CA)
Inventor: SCHROEDER DUANE
IPC: B30B15/30
Filed: 2004-01-29
Abstract: The material compactor (10) generally includes a feed apparatus (12) and a final compaction apparatus (16). The final compaction apparatus (16) generally includes a compaction chamber (32) having confronting compression plates (44, 46) and an adjustably taperable portion (54). The area of the inner cavity (54) of the final compaction chamber can be adjusted to become measurably smaller (tapered) or larger at the opened discharge or expelling end (58).  Consequently, compacting movement of the material within the compaction chamber and through the chamber significantly subjects the material to restrictive compacting pressure which in turn compacts the material and performs liquid separation with each operationally continuous movement through the final compaction apparatus and out an open discharge port (58).
Patent CA-2529091-A1 (CA)
Title: Mobile-trailer tracking system and method
Inventor: HSIAO VICTOR K
IPC: G08G1/127
Filed: 2003-06-13
Abstract: A position tracking system for a plurality of mobile tractors (202) and trailers (208) includes an unique electronic identifier (210) for each of a plurality of trailers. For each tractor of a plurality of tractors, the position tracking system includes a navigation system for determining a current position of the tractor, an electronic identifier reader (308) for acquiring the electronic identifier (210) of a trailer (208) coupled to the tractor (202), and a position-reporting subsystem for reporting to a remote system the current position of the tractor and the electronic identifier (21 0) of the trailer (208) coupled to the tractor (202). In addition, the position tracking system includes, at each facility of a plurality of fixed-location facilities, one or more trailers located within the facility, and a trailer- presence reporting subsystem for reporting to the remote system the presence of the one or more trailers located within the facility.
Patent CA-2534266-A1 (CA)
Inventor: SHEETS PHILIP
IPC: B67C3/14
Filed: 2004-07-30
Abstract: A system for processing a simplified plastic container (C) that is to be filled with a hot product includes the step of blow-molding parison to form a container body, where the container body has a neck, a base, a side surface relatively free of structural geometry that surrounds an interior of the container body and, prior to being filled with the hot product, a projection (12) extending from the container body. After the container body is filled with a hot product in a production line, the neck of the filled container body is capped with a cap and then, the container body is cooled. During the cooling operation, the hot product is contracted so that the projection extending from the container can be pushed (P) into the container body like a traditional push-up so that the resultant, filled and cooled container body is relatively free of structural geometry.
Patent CA-2534279-A1 (CA)
Title: Apparatus and method for controlling operational states of medium access control layer in a broadband wireless access communication system
Inventor: KIM SO-HYUN
IPC: H04L12/28
Filed: 2004-08-30
Abstract: ABSTRACT Disclosed is a method for controlling an operational state of a medium access control layer in a broadband wireless access communication system. The method includes the steps of performing an uplink access of a contention-based scheme to an access point using resources required to perform the uplink access according to the contention-based scheme when data to be transmitted in an access state is detected, and being allocated resources required to perform an uplink access of a contention-free scheme from the access point in a case of failing in the uplink access of the contention-based scheme; and performing a state transition from the access state into the traffic state in a case of having been allocated the resource required for the contention-free scheme, and performing the uplink access of the contention-free scheme to the access point using the allocated resource in the traffic state.
Patent CA-2534792-A1 (CA)
Title: A system and method for transferring a computing environment between computers of dissimilar configurations
Inventor: CROSBIE DAVID
IPC: G06F15/177
Filed: 2006-01-18
Abstract: A system and method for migrating a computer to another computer having dissimilar hardware, wherein a preparation stage for the transfer of a disk image between the origin and target computer comprise analyzing the origin computer and modifying certain parameters therein while operating under its native operating system. After the modification an image of the origin computer is taken and sent to the second computer. The second computer can then boot the image as the necessary changes for booting the target machine were made at the origin computer. The invention is particularly useful for transferring physical computer to a virtual machine environment, where it minimizes the time the origin computer is out of service, where the transfer may occur remotely to the origin computer or the target computer. Most importantly, the invention provides a very high rate of success in migrating a physical system to a virtual system.
Patent CA-2535861-A1 (CA)
Title: Clothes dryer wrinkle release cycle
Inventor: DUNSBERGEN KIRK M
IPC: D06F58/44
Filed: 2006-02-10
Abstract: A clothes dryer is provided with a wrinkle release cycle premised upon the exhaust temperature of the dryer. When a user selects the wrinkle release cycle, heat is added to the clothes tumbling in the dryer drum until the dryer exhaust temperature reaches a first predetermined value of approximately 150°F. Then, the clothes continue to tumble in the drum without heat until the exhaust temperature decreases to a second predetermined value of approximately 100°F. After the cool down temperature is reach, the machine sounds a signal and continues to tumble the clothes in the drum for another 5-10 minutes before ending the cycle.
Patent CA-2536489-A1 (CA)
Inventor: JIN BETTY
IPC: A23K20/195
Filed: 2004-08-26
Abstract: The present invention related to compositions including berberine or derivatives thereof of formula (1) (where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and X are as defined in claim 1) and/or polymeric dialdehyde chosen from compounds such as dialdehyde polysaccharides (such as oxidised cellulose (oxycellulose) or oxidized starch (oxystarch) or poly(acrolein/acrylic acid) for the treatment of gastrointestinal functional disorders and related conditions, including Irritable Bowel Syndrome;  Inflammatory Bowel Disease; Colitis,Crohn~s disease and/or for promoting weight gainin animals including humans.
Patent CA-2537477-A1 (CA)
Title: Capsules containing active substance pellets with different release profiles
Inventor: ANSCHUETZ SERGEJ
IPC: A23L33/15
Filed: 2004-08-28
Abstract: The invention relates to a capsule containing different active substance pellets having at least two different active substances, which differ with regard to their release profile in the gastrointestinal tract. These active substances are selected from the group consisting of vitamins, mineral substances, trace elements, unsaturated fatty acids, amino acids and/or plant extracts and substances. The different release profiles depict a rapid, medium and/or slow dissolution of the active substance pellets. This controlled release leads to a target-oriented resorption of the active substances into the different resorption areas in the gastrointestinal tract. The dosage form prepared according to the invention enables the bioavailability to be improved to a high degree even in the event of a larger number of available active substances..