baber/WOPTO huggingface dataset:
Patent WO-2019168985-A1 (WO)
Inventor: WATKINS GREGORY A
IPC: A61K31/433
Filed: 2019-02-27
Abstract: A composition comprising a small molecule therapeutic agent and an organic acid compound is described. The small molecule therapeutic agent (i) has a water solubility at room temperature of less than about 1.0 g/L and (ii) is a base. The organic acid is one that (i) has a water solubility at room temperature of between 0.1 and 10 or of less than about 20 g/L, (ii) has a molar mass of less than 500 grams per mole, and/or (iii) maintains a pH of the composition when hydrated in its environment of use of between 3.0-6.5 for a period of at least about 30 days. The organic acid, particularly when it is present in the composition in stoichiometric excess, improves solubility of the small molecule therapeutic agent to provide a composition that delivers the therapeutic agent for a sustained period of time.
Patent WO-2019169036-A1 (WO)
Inventor: WOLTERS MADELINE
IPC: A61F2/44
Filed: 2019-02-27
Abstract: A variable height intervertebral spine implant (10, 110) is adjustable in situ having first and second trapezoidal components (12, 14) oriented such that the short surfaces/sides of their parallel surfaces/sides are adjacent, forming a first wedge- shaped pocket (16a) between opposing first skew surfaces/sides (27, 43) of the first and second components (12, 14) on a first end, and a second wedge-shaped pocket (16b) between opposing second skew surfaces/sides (28, 44) of the first and second components (12, 14) on a second end. First and second lateral flanges (23, 24; 39, 40) of both the first and second components (12, 14) cooperate to connect the first and second components together, and to allow height adjustment between the first and second components. A first wedge (50) situated in the first pocket (16a) and a second wedge (51) situated in the second pocket (16b) are connected via a drive mechanism (58) that effects concerted movement thereof whereby contraction increases implant height while expansion decreases implant height. The wedges (50, 51) ride against the skew sides (27, 43; 28, 44) of the components (12, 14).
Patent WO-2019169195-A1 (WO)
Inventor: BAYLESS RONNIE E
IPC: A61K47/36
Filed: 2019-02-28
Abstract: The present disclosure generally relates to film-forming compositions and capsules formed from such compositions, including processes for using such compositions to make capsules. In some embodiments, the film-forming compositions are free of animal products and carrageenan.
Patent WO-2019169374-A1 (WO)
Inventor: LEONARD SHANE
IPC: G06Q20/00
Filed: 2019-03-03
Abstract: Apparatus and methods for providing transparency, security, and auditability to a loan servicing process by encoding Loan Actions and associated Action data, onto a Blockchain. The Blockchain is distributed to Participants in the Loan, such as the Borrowers, Regulators, Servicers, and Vendors. The present disclosure further provides a method for homogenizing a variety of Vendor Formats for inclusion on the Blockchain and memorializing execution of a smart contract on the Blockchain. simplifying Transactions such as assignment of the rights of a Participant are simplified and memorialized and accessible via a communications network.
Patent WO-2019173533-A1 (WO)
Title: Compositions and methods for treating hyperproliferative skin disorders
Inventor: LAU JOHNSON YIU-NAM
IPC: A61K31/5377
Filed: 2019-03-06
Abstract: Compositions and methods are provided that are effective in treating skin hyperproliferative disorders. These include a topical pharmaceutical preparation that includes a compound that has two or more of a SRC-kinase inhibiting activity, a tubulin polymerization inhibiting activity, an activity that arrests the cell cycle at G2/M, and an activity that induces apoptosis. The compound KX01 is provided as an example of such a compound. The topical pharmaceutical preparation further includes a vitamin D derivative or a retinoid, where the combination provides a synergistic effect. Use of the topical pharmaceutical preparation can be combined with exposure to blue, UVA, or UVB light, which provides a synergistic effect.
Patent WO-2019173540-A1 (WO)
Title: Chopping switch time-skew calibration in time-interleaved analog-to-digital converters
Inventor: VERBRUGGEN BOB
IPC: H03M1/12
Filed: 2019-03-06
Abstract: An example time-skew calibration circuit includes a plurality of first circuits (702), each including a first accumulator (720) and a second accumulator (722). The time-skew calibration circuit further includes a plurality of second circuits (704), each including a first adder (724) coupled to outputs of the first accumulator and the second accumulator, and a first subtractor (726) coupled to the outputs of the first accumulator and the second accumulator. The time-skew calibration circuit further includes a decision circuit (727) configured to combine an output of the first adder and an output of the first subtractor.
Patent WO-2019177919-A1 (WO)
Title: Systems and methods for maximizing wind energy
Inventor: HAJ-MAHARSI MOHAMED
IPC: F03D7/06
Filed: 2019-03-11
Abstract: A vertical axis wind turbine (VAWT) system includes a pillar having a vertical rotational axis, a plurality of blades connected to the pillar, each of the plurality of blades comprising a plurality of flaps that open or close in response to a wind direction, and a control system configured to control the extent of opening and closing of the flaps based on the wind direction and wind intensity. A method for maximizing energy harvesting in a VAWT includes providing a pillar having a vertical rotational axis, connecting a plurality of blades to the pillar, each of the plurality of blades comprising a plurality of flaps that open or close in response to a wind direction, and connecting a control system to the plurality of blades, the control system configured to control the extent of opening and closing of the flaps based on the wind direction and wind intensity.
Patent WO-2019203958-A1 (WO)
Title: Apparatus for producing a corrugated product
Inventor: KOHLER HERBERT
IPC: B31F1/28
Filed: 2019-03-12
Abstract: An apparatus for introducing transverse trapezoidal corrugations into a traveling web is provided, and includes a plurality of corrugating rollers for imparting corrugations to the web. In disclosed embodiments four such rollers are provided in a roller train defining respective first, second and third nips therebetween, wherein the teeth of the first and second rollers have rounded distal faces and those of the third and fourth rollers have flattened distal faces. Methods of yielding a trapezoidal corrugated web also are disclosed.
Patent WO-2019178410-A1 (WO)
Title: Micro-rna and obesity
Inventor: PANDOLFI PIER PAULO
IPC: C12N15/11
Filed: 2019-03-14
Abstract: The present disclosure provides a method of treating or preventing metabolic disorders by administering agents that inhibit the activity of microRNAs that modulate metabolism.
Patent WO-2020076360-A1 (WO)
Inventor: DAHL VINCENT
IPC: B25B13/36
Filed: 2019-03-22
Abstract: A ratcheting brake bleeder wrench is provided which sealingly couples to a bleed valve. The brake bleeder wrench has an internal fluid passageway which allows egress of fluid from a hydraulic brake; system. The ratcheting brake bleeder wrench is used to open the bleed valve, allowing egress of fluid, remains in place during the bleeding operation, and reverses direction up;on completion of bleeding to tighten the bleed valve back into sealing relationship with the hydraulic brake system.
Patent WO-2019217176-A1 (WO)
Title: Solidifying filler material for well-integrity issues
Inventor: ALJUBRAN MOHAMMAD
IPC: E21B47/06
Filed: 2019-05-01
Abstract: In some aspects, a method includes imaging a casing, completed wellbore, or open wellbore. An integrity problem is with the casing, completed wellbore, or open wellbore is determined based on the imaging. A placement zone for a filler, a filler amount, and filler parameters for the integrity problem is determined. The filler in the filler amount is injected in the placement zone. The filler is solidified at the placement zone.
Patent WO-2019213279-A1 (WO)
Title: Infrared imaging systems and methods for oil leak detection
Inventor: ISRAELSEN MARK
IPC: G21C17/07
Filed: 2019-05-01
Abstract: A system for detecting an oil leak can include: at least one infrared imaging sensor; and an imaging analysis computer operably coupled with the at least one infrared imaging sensor. The imaging analysis computer can be configured to control any infrared imaging sensor and acquire infrared images therefrom at any rate and in any duration. The imaging analysis computer can be configured to analyze the infrared images in order to detect an oil leak. The imaging analysis computer can be configured to detect oil on a surface (e.g., solid surface or water surface) where oil should not be (or is not present in a baseline) in order to determine that there is an oil leak in the vicinity.
Patent WO-2019222669-A1 (WO)
Inventor: KAMIKAWA TAKESHI
IPC: H01L21/306
Filed: 2019-05-17
Abstract: L'invention concerne un procédé de division d'une barre d'un ou de plusieurs dispositifs. La barre est constituée de couches semi-conductrices à base de nitrure III de type îlot cultivées sur un substrat à l'aide d'un masque de limitation de croissance; les couches semi-conductrices à base de nitrure III de type îlot sont retirées du substrat à l'aide d'un procédé de surcroissance latérale épitaxiale (ELO); puis la barre est divisée en un ou plusieurs dispositifs à l'aide d'un procédé de clivage.
Patent WO-2019222734-A1 (WO)
Title: Learning data augmentation policies
Inventor: VASUDEVAN VIJAY
IPC: G06N3/04
Filed: 2019-05-20
Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for learning a data augmentation policy for training a machine learning model. In one aspect, a method includes: receiving training data for training a machine learning model to perform a particular machine learning task; determining multiple data augmentation policies, comprising, at each of multiple time steps: generating a current data augmentation policy based on quality measures of data augmentation policies generated at previous time steps; training a machine learning model on the training data using the current data augmentation policy; and determining a quality measure of the current data augmentation policy using the machine learning model after it has been trained using the current data augmentation policy; and selecting a final data augmentation policy based on the quality measures of the determined data augmentation policies.
Patent WO-2019226546-A1 (WO)
Title: Method and apparatus for ct scanning of longer whole cores
Inventor: CALISKAN SINAN
IPC: G01N23/046
Filed: 2019-05-20
Abstract: Embodiments of the disclosure include an extended length core sample scanning apparatus that enables the imaging of extended length core samples using medical-type CT scanners. The extended length core sample scanning apparatus has a frame that defines a U-shaped receptacle that receives core housing containing the core sample when the core sample is placed in a CT scanner. The extended length core sample scanning apparatus may have two or more rollers located in the U-shaped receptacle to enable translation of the extended length core sample through a CT scanner during scanning. The rollers may also provide for a minimum clearance between the core housing and the walls of the U-shaped receptacle. Methods of imaging an extended length core sample are also provided.
Patent WO-2019231855-A1 (WO)
Title: Audio device
Inventor: WONG TENVOON
IPC: A61F11/14
Filed: 2019-05-24
Abstract: An audio device (e.g., hearing aid) can optionally have a radio-frequency antenna that includes an antenna structure on a flexible printed circuit board. The antenna structure can have one or metal traces disposed on the flexible printed circuit board, the antenna structure extending over an area that substantially coincides with the area of the flexible printed circuit board. The flexible printed circuit board is foldable into a three-dimensional structure that can be disposed in a folded configuration in an audio device (e.g., hearing aid).
Patent WO-2019231979-A1 (WO)
Title: Modular fueling station
Inventor: NORTON BART
IPC: F17C13/04
Filed: 2019-05-29
Abstract: A fueling station can include an outer housing comprising a housing volume, a first fluid bladder positioned within the housing volume and configured to hold a first fluid, a second fluid bladder positioned within the housing volume and configured to hold a second fluid, a first fluid conduit in fluid communication with the first fluid bladder, a second fluid conduit in fluid communication with the second bladder, a first hose positioned at least partially outside the outer housing and in fluid communication with both the first and second fluid conduits, and a bi-directional first nozzle connected to an end of the first hose opposite the first and second fluid conduits. The bi-directional first nozzle can be configured to simultaneously release fluid from the first hose and to collect fluid into the first hose. The first fluid bladder can be configured to release fluid through the first conduit in response to introduction of fluid into the second fluid bladder via the second conduit. The second fluid bladder can be configured to release fluid through the second conduit in response to introduction of fluid into the first fluid bladder via the first conduit.
Patent WO-2020023113-A1 (WO)
Title: Electric safety valve with well pressure activation
Inventor: VICK JR
IPC: E21B34/12
Filed: 2019-05-30
Abstract: A safety valve may include: an outer housing comprising a central bore extending axially through the outer housing; a flow tube including: a translating sleeve; and a flow tube main body disposed within the translating sleeve, wherein the flow tube main body has an upper end and a lower end; a piston operable to transmit a force to the translating sleeve; a flapper valve disposed on a distal end of the outer housing; and an electromagnet assembly operable to maintain the safety valve in an open state.
Patent WO-2019246520-A1 (WO)
Title: Aminobisphosphonates comme agents d'inversion de latence et traitements combinés pour le traitement du vih
Inventor: SORIANO-SARABIA NATALIA
IPC: A61K35/17
Filed: 2019-06-21
Abstract: La présente invention concerne de nouveaux procédés de traitement du VIH. En particulier, la présente invention concerne des aminobisphosphonates comme agents d'inversion de latence (LRA), et des procédés de traitement du VIH par administration à un sujet d'une combinaison de bisphosphonates et de cellules T γδ. Dans certains modes de réalisation, ces interventions peuvent être associées à d'autres agents d'inversion de latence, par exemple, des inhibiteurs de désacétylases d'histones (HD AC), et d'autres agents immunothérapeutiques d'élimination du VIH (par exemple, généralement des anticorps de neutralisation du VIH).
Patent WO-2020005937-A1 (WO)
Title: Techniques for enabling and integrating in-memory semi-structered data and text document searches with in-memory columnar query processing
Inventor: LIU ZHEN HUA
IPC: G06F16/81
Filed: 2019-06-25
Abstract: A "hybrid derived cache" stores semi-structured data or unstructured text data in an in-memory mirrored form and columns in another form, such as column-major format. The hybrid derived cache may cache scalar type columns in column-major format. The structure of the in-memory mirrored form of semi-structured data or unstructured text data enables and/or enhances access to perform path-based and/or text based query operations. A hybrid derived cache improves cache containment for executing query operations. The in-memory mirrored form is used to compute queries in a transactionally consistent manner through the use of an invalid vector that used to determine when to retrieve the transactionally consistent persistent form of semi-structured data or unstructured text data in lieu of the in-memory form.
Patent WO-2020005994-A1 (WO)
Inventor: SCHIBEL ANNA E P
IPC: C12Q1/6869
Filed: 2019-06-25
Abstract: L'invention concerne des dispositifs et des procédés pour commander la translocation d'un acide nucléique simple brin par l'intermédiaire d'un capteur ou d'un lecteur de nanopore.
Patent WO-2020055511-A1 (WO)
Title: Electrical connectivity between detachable components
Inventor: FINKEL PAUL
IPC: G03B17/12
Filed: 2019-07-25
Abstract: In one aspect of the present disclosure, a digital image capturing device (DICD) is disclosed that includes a device body with a printed circuit board (PCB), and an integrated sensor-lens assembly (ISLA) that is configured for releasable connection to the device body. The PCB defines a plurality of openings that extend therethrough and includes a plurality of connector pins that are fixedly positioned within the openings. The ISLA includes at least one connective surface that is configured for contact with the connector pins to establish electrical communication between the device body and the ISLA.
Patent WO-2020076392-A1 (WO)
Inventor: YOON DOE HYUN
IPC: G06F12/0811
Filed: 2019-07-29
Abstract: Methods, systems, and apparatus for updating machine learning models to improve locality are described. In one aspect, a method includes receiving data of a machine learning model. The data represents operations of the machine learning model and data dependencies between the operations. Data specifying characteristics of a memory hierarchy for a machine learning processor on which the machine learning model is going to be deployed is received. The memory hierarchy includes multiple memories at multiple memory levels for storing machine learning data used by the machine learning processor when performing machine learning computations using the machine learning model. An updated machine learning model is generated by modifying the operations and control dependencies of the machine learning model to account for the characteristics of the memory hierarchy. Machine learning computations are performed using the updated machine learning model.
Patent WO-2020028730-A1 (WO)
Title: Aluminum alloys for die casting
Inventor: PALANIVEL SIVANESH
IPC: C22C21/00
Filed: 2019-08-01
Abstract: A high performance die castable aluminum alloy is described, wherein the aluminum alloy is characterized as having a high yield strength and high conductivity, and also a high flowability and low susceptibility to hot tearing when die cast.
Patent WO-2020033914-A1 (WO)
Title: User equipment capability indication of receive beamforming for cell identification
Inventor: RAGHAVAN MANASA
IPC: H04W48/16
Filed: 2019-08-09
Abstract: An apparatus of a New Radio (NR) User Equipment (UE), a method, and a system. The apparatus includes a Radio Frequency (RF) interface, and processing circuitry coupled to the RF interface. The processing circuitry is to: generate a signal including capability information of the UE, wherein a time period for intra-frequency cell detection and measurement for the UE is based on the capability information; and cause a transmission of the signal within a cellular network to include the UE using the RF interface.
Patent WO-2020046572-A1 (WO)
Title: Procédé d'enregistrement audio dans un journal de transaction distribué inaltérable pour une vérification et un audit de bout en bout
Inventor: YANG YUNHAI
IPC: H04L9/32
Filed: 2019-08-13
Abstract: L'invention concerne un appareil informatique et un appareil implémenté par ordinateur pour enregistrer un contenu audio dans un enregistreur audio. Un contenu audio est transmis à partir d'un dispositif de communication source. Au moins un dispositif de communication récepteur reçoit le contenu audio. Le contenu audio est enregistré dans un enregistreur audio, par exemple par le dispositif de communication source et le dispositif de communication récepteur. Un hachage du contenu audio est exécuté, et le hachage du contenu audio et des paramètres de communication associés au contenu audio sont stockés dans une chaîne de blocs.
Patent WO-2020037128-A1 (WO)
Title: Freeze concentration for urine-based fertilizer production
Inventor: NOE-HAYS ABRAHAM
IPC: C05F17/00
Filed: 2019-08-15
Abstract: A system for generating a concentrated product from a feedstock includes a feedstock chamber to which the feedstock is provided, a heat exchanger assembly in thermal communication with the feedstock chamber, the heat exchanger assembly being configured to freeze the feedstock in the feedstock chamber, an output flow arrangement configured to carry liquid from the feedstock chamber as the feedstock thaws, the output flow arrangement comprising a flow controller, a sensor disposed along the output flow arrangement or the heat exchanger assembly, the sensor being configured to measure a characteristic of the liquid, the characteristic being indicative of a solute concentration level of the liquid or the heat exchanger assembly, and a processor responsive to the characteristic and configured to control the flow controller to, based on the solute concentration level, direct the liquid passing through the output flow arrangement to define a plurality of products at different concentration levels, the plurality of products comprising the concentrated product.
Patent WO-2020047080-A1 (WO)
Inventor: ZHOU HUA
IPC: H04W72/02
Filed: 2019-08-28
Abstract: A wireless device receives radio resource control message(s) comprising configuration parameters of a cell. The configuration parameters comprise a first configuration of a first sounding reference signal of the cell in a first power state, and a second configuration of a second sounding reference signal of the cell in a second power state. A first command indicating transition of the cell into the first power state is received. In response to the first command, the first sounding reference signal is transmitted via the cell. A second command indicating transition of the cell into the second power state is received. In response to the second command, the second sounding reference signal is transmitting via the cell.
Patent WO-2020051234-A1 (WO)
Title: Botanical antioxidants
Inventor: RANA JATINDER
IPC: A61P39/06
Filed: 2019-09-04
Abstract: A botanical extract that exhibits antioxidant activity, wherein the botanical extract is at least an extract from the leaf of a plant from the genus  Vaccinium .
Patent WO-2020072657-A1 (WO)
Title: Non-public network discovery, selection, and access control in vertical domain
Inventor: LIAO CHING-YU
IPC: H04W48/16
Filed: 2019-10-02
Abstract: In one embodiment, an apparatus of a User Equipment (UE) device includes memory storing non-public network (NPN) configuration information, a radio frequency (RF) interface, and processing circuitry coupled to the memory and the RF interface. The RF interface receives information broadcast by a radio access network (RAN) node of the particular NPN, where the information includes a NPN indicator indicating that the RAN node supports a NPN and NPN service information indicating services supported by the particular NPN. The processing circuitry establishes, in response to detecting the NPN indicator in the information received from the RAN node, a connection to the particular NPN based on the NPN configuration information and the NPN service information received from the RAN node.
Patent WO-2020077149-A1 (WO)
Inventor: AL-ALI AMMAR
IPC: H04W4/80
Filed: 2019-10-10
Abstract: Medical patient monitoring sensor devices including a disposable sensor assembly and a reusable pairing device are disclosed. The disposable sensor assembly can collect patient physiological data and provide power for the reusable pairing device. The reusable pairing device can establish wireless communication with a monitoring device. Once the reusable pairing device receives patient physiological data from the disposable sensor assembly, the reusable pairing device can wirelessly transmit the data to the computing device via the wireless communication.
Patent WO-2020082028-A1 (WO)
Title: Systems and methods for a power-generating thermogalvanic brick
Inventor: PHELAN PATRICK
IPC: B28B11/04
Filed: 2019-10-18
Abstract: Various embodiments of systems and methods for a thermogalvanic brick are disclosed.