baber/WOPTO huggingface dataset:
Patent CA-3148226-A1 (CA)
Inventor: TRAVERSO CARLO GIOVANNI
IPC: A61K31/375
Filed: 2020-08-12
Abstract: La présente invention concerne des articles et des modes d'administration d'un agent thérapeutique à un sujet. Ces articles et modes peuvent être utiles, dans certains cas, pour l'administration d'agents thérapeutiques au côlon d'un sujet. Dans certains modes de réalisation, un article est conçu pour libérer un agent inducteur de sécrétion, par exemple, pour stimuler la libération de fluides intestinaux. Dans certains modes de réalisation, l'article comprend un agent thérapeutique de sorte que la libération stimulée de fluide intestinal augmente la quantité d'agent thérapeutique disponible pour l'absorption par le côlon. Par exemple, dans certains modes de réalisation, les articles et les modes de l'invention favorisent avantageusement une absorption accrue d'agents thérapeutiques chez des sujets par comparaison avec des agents thérapeutiques généralement administrés sans constituants supplémentaires tels qu'un agent inducteur de sécrétion. Dans certains modes de réalisation, les articles et les modes de l'invention peuvent augmenter la motilité du côlon d'un sujet. L'augmentation des contractions et du mouvement du fluide dans le côlon provoquée par l'augmentation de la motilité peut avantageusement faciliter la dissolution ou l'absorption de l'agent thérapeutique.
Patent CA-3149510-A1 (CA)
Title: Dump-truck fluid assistance system and method
Inventor: BEAVER PAT
IPC: B05B15/60
Filed: 2020-07-13
Abstract: A dump-truck fluid assistance system and method for prevention and remediation of material sticking to the truck bed and dampening generation of dust, at different stages of loading, transport, and dumping operations. Fluid is emitted from one or more outflow manifolds inside the bed of the dump truck for one or more purposes of lubricating the truck bed, regulating the temperature of the truck bed, physically flushing material from the truck bed, and dampening generation of airborne particles or dust. Under the control of a controller having a controller transceiver, directed via a cab operator transceiver or remote operator transceiver, a fluid pump sends fluid from a fluid reservoir via a fluid line into the outflow manifolds that emit the flow of fluid variously as spray, stream, jet, drip, or weep, into the bed of the dump truck.
Patent CA-3151346-A1 (CA)
Inventor: KAY MARK A
IPC: C07K14/195
Filed: 2020-08-17
Abstract: La présente invention concerne des procédés et des compositions pour faciliter une recombinaison homologue (RH) à base de virus adéno-associé (AAV) efficace. Les procédés selon l'invention comprennent une étape de mise en contact d'une cellule (par exemple, une population de cellules) avec un inhibiteur de la ribonucléotide réductase, qui permet d'obtenir une efficacité de RH accrue par rapport à la réalisation d'une RH en l'absence de l'inhibiteur. La cellule est également mise en contact avec un virus adéno-associé recombiné (rAAV) comprenant un ADN donneur ayant une cassette de séquence (c'est-à-dire une séquence nucléotidique d'intérêt) flanquée de bras d'homologie facilitant l'intégration de la cassette de séquence dans un locus génomique cible par l'intermédiaire d'une RH.
Patent CA-3152051-A1 (CA)
Inventor: GREER JOHN M
IPC: A61B5/00
Filed: 2020-08-18
Abstract: Systems and methods of using an animal wellness notification system to determine the wellness of an animal, the systems and methods comprising: attaching an animal wellness notification system component to an animal, monitoring the temperature of the animal to determine if the animal's temperature remains outside a selected temperature range for a selected time duration, and providing notice if the animal's temperature remained outside the selected temperature range for the selected time duration.
Patent CA-3152888-A1 (CA)
Title: Method for the production of a catalytically active dna molecule having improved activity and its use in a method of treating asthma
Inventor: RUPP THOMAS
IPC: A61K31/7088
Filed: 2020-10-07
Abstract: The present invention refers to a method for the production of a catalytically active DNA molecule resulting in a significantly decreased amount of impurities in the catalytically active DNA molecule, to a catalytically active DNA molecule obtainable by such method and a pharmaceutical composition comprising such catalytically active DNA molecule as well as their use in a method for the prevention and/or treatment of a GATA-3-driven disease.
Patent CA-3154439-A1 (CA)
Title: Cutting unit with movable side walls
Inventor: SUDHUES STEFFEN
IPC: A01D61/00
Filed: 2020-10-06
Abstract: The present invention relates to a cutting unit ( 2) for attachment to a harvester. In order to reduce the free spaces at the outer ends of conveying elements, in which the conveying elements are ineffective depending on the pivoting position of the frame parts in relation to one another, it is proposed that the side walls (14) are designed to be movable transversely to the working direction (A) of the cutting unit (2) and to the frame ( 22) or the associated frame parts (24a, 24c).
Patent CA-3157074-A1 (CA)
Inventor: AHVAZI BEHZAD
IPC: A61K31/192
Filed: 2022-05-02
Abstract: Extracts of a plant, fungus, waste, or part thereof, compositions comprising same, and methods of preparing and using same are provided. Extraction may be conducted using acetone/water extraction solution at predetermined ratios to yield extracts comprising desired phytocannabinoids, cannabimimetic compounds, terpenes, flavonoids, alkaloids, waxes, and other secondary metabolites. A composition comprises the extract and at least one acceptable carrier. A method of treating, preventing, or ameliorating a disease in a subject comprises administering to the subject an effective amount of the extract or composition.
Patent CA-3157847-A1 (CA)
Inventor: LOTHIAN GREG
IPC: G01L5/102
Filed: 2022-05-06
Abstract: An instrumented load cell device for use in fitness applications. A load cell is anchored between an anchor point and a fitness user via a resistance band or the like. The device displays the force generated by the user and operably connectable to a supporting fitness app on a mobile device by a network connection.
Patent CA-3160300-A1 (CA)
Title: Churn prevention using graphs
Inventor: RAMAKRISHNAN ROHITH
IPC: G06F17/00
Filed: 2022-05-25
Abstract: A method implements chum prevention using graphs. The method includes receiving clickstream data, which includes an event, of a user session with an application. The method further includes identifying the event as corresponding to a chum user account and mapping the event to a pair of nodes of a graph. The method further includes updating a chum user count of the pair of nodes in response to identifying the event as corresponding to the chum user account. The method further includes identifying an edge of the graph, corresponding to the pair of nodes. The method further includes updating a value of the edge using an active user count and the chum user count presenting an update responsive to the value.
Patent CA-3163194-A1 (CA)
Title: Dispositif d'accrochage
Inventor: TAYLOR GUY
IPC: A47G25/14
Filed: 2020-11-23
Abstract: L'invention concerne un cintre pour vêtements (10) comprenant une partie de mise en prise de rail (16) et des moyens de support de vêtements sous la forme d'un élément allongé déformable (20). L'extrémité de l'élément allongé distale de la partie de mise en prise avec le rail comprend une première partie (22) d'un mécanisme de liaison tel que l'élément allongé (22) peut être déformé en arrière sur lui-même et relié à une seconde partie (24) du mécanisme de liaison du cintre pour former une boucle fermée. L'élément allongé (20) comprend une bride latérale (32) sur sa longueur.
Patent CA-3163325-A1 (CA)
Inventor: GOONERATNE CHINTHAKA PASAN
IPC: E21B34/06
Filed: 2020-12-17
Abstract: Systems and methods for actuation of downhole devices are disclosed. The system includes a first cylindrical pipe having one or more first materials attached to an outer surface of the first cylindrical pipe, a second cylindrical pipe co-axial with the first cylindrical pipe and having a diameter greater than the first cylindrical pipe, the second cylindrical pipe comprising one or more second materials disposed on an inner surface of the second cylindrical pipe, wherein the first materials generate one or more signals when the first materials come in contact with the second materials, and a digital logic circuit configured to receive the one or more signals as input, and generate an output based on the input, the output configured for actuation of the downhole devices.
Patent CA-3164309-A1 (CA)
Title: Treatment of neurological disorders with avermectins
Inventor: WAKSAL SAMUEL D
IPC: A61K45/06
Filed: 2021-01-11
Abstract: Disclosed are methods of use of Ivermectin for the prevention, treatment and control of various neurological disorders in humans and novel formulations of pharmaceutical compositions comprising Ivermectin.
Patent CA-3164325-A1 (CA)
Title: Alpha-5 beta-1 inhibitors
Inventor: SHEPPARD DEAN
IPC: A61K38/00
Filed: 2020-12-09
Abstract: The disclosure provides, inter alia, alpha-5 beta-1 inhibitors, pharmaceutical compositions comprising alpha-5 beta-1 inhibitors, methods for treating diseases using alpha-5 beta-1 inhibitors, and processes for making alpha-5 beta-1 inhibitors.
Patent CA-3165641-A1 (CA)
Inventor: DE ANGELIS ALBERTO RENATO
IPC: B01D53/14
Filed: 2021-02-05
Abstract: L'invention concerne un procédé de traitement de mélanges de gaz contenant du gaz acide, permettant une élimination dudit gaz acide des mélanges de gaz, comprenant une étape d'absorption exécutée sur un mélange de gaz contenant un gaz acide au moyen d'un système de solvant contenant au moins un solvant d'absorption de liquide pour éliminer, du mélange de gaz, le gaz acide contenu en son sein et pour former un mélange de gaz pauvre, duquel au moins une partie du gaz acide a été éliminée, et un solvant enrichi contenant le gaz acide ; et une étape de régénération, lors de laquelle le solvant enrichi est soumis à une étape de séparation gaz/liquide par un procédé flash de façon à se trouver séparé du gaz acide absorbé et à produire un flux de gaz acide et un solvant régénéré qui est remis en circulation vers l'étape d'absorption ; le système de solvant contenant au moins un solvant d'absorption de liquide choisi parmi des liquides ioniques commutables.
Patent CA-3167508-A1 (CA)
Inventor: BEUSCHEL RALF
IPC: G01S7/48
Filed: 2021-02-01
Abstract: The invention relates to a device (1) for generating backscattering histogram data (RHD0) for determining a diffuse backscattering in an optical delay measurement, comprising at least one histogram accumulation unit (HA0 to HAX), having multiple signal inputs, in order to receive time-correlated histogram data (ZHD0 to ZHDP), and wherein the histogram accumulation unit (HA0 to HAX) is designed to generate backscattering histogram data (RHD0) based on the time-correlated histogram data (ZHD0 to ZHDP) received at the signal inputs.
Patent CA-3168256-A1 (CA)
Title: Bassinet accessory for a playard
Inventor: PACELLA JONATHAN M
IPC: A47D11/00
Filed: 2021-01-18
Abstract: A bassinet accessory for a foldable playard, wherein the bassinet and playard are folded and unfolded together. When unfolded, the bassinet is relatively shallow from a top of the playard so that a caregiver may more easily place a child into, and remove the child from, the bassinet. A bassinet mattress is supported by a central hub on the bottom of the bassinet and four support tubes coupled to the hub and extending to respective bottom comers of the bassinet. During folding, the bassinet hub travels in a vertical direction and the support tubes rotate from a horizontal to a vertical position, becoming parallel with respective legs of the playard. Thus, in the compact folded configuration, the bassinet hub is surrounded by and within the folded frame of the playard or flush with the top of the playard (so as not to appreciably extend beyond a top of the playard).
Patent CA-3170013-A1 (CA)
Title: Method of managing resources based on goods, device and medium
Inventor: ZHU XINHE
IPC: G06Q10/0631
Filed: 2022-08-11
Abstract: Pertaining to the field of goods management technology, the present invention discloses a method of managing resources based on goods, and corresponding device and medium, of which the method comprises: receiving a request for entrusted management of goods and a resources allocating request submitted by a merchant, sending a goods collecting instruction to a collecting equipment of the designated warehouse, receiving goods collection data returned by the collecting equipment, and calculating an allocatable quota of resources of the merchant with respect to the received collection data through a quota algorithm model. The present invention can solve risk problems concerning warehouse receipts falsification and goods falsification by illegal merchants, inaccurate value accounting of entrusted management of goods, and inaccurate calculation of available resources allocation quota, solve problems concerning traditional artificial multi-scenario interferences, and unduly many approval links, and enhance the utilization rate of resources.
Patent CA-3170924-A1 (CA)
Inventor: BURD TAMMY
IPC: G01N35/10
Filed: 2008-10-02
Abstract: The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.
Patent CA-3173722-A1 (CA)
Inventor: KINCAID JOHN
IPC: A61P25/28
Filed: 2021-03-26
Abstract: L'invention concerne des composés et des sels qui présentent une sélectivité élevée et une activité inhibitrice vis-à-vis de mTORC1 et leurs utilisations pour le traitement d'une maladie.
Patent CA-3174382-A1 (CA)
Inventor: ALBISTON BEAU
IPC: C07K19/00
Filed: 2022-06-08
Abstract: A computer-implemented method includes monitoring a brain state at a neurometric interface, receiving a first signal from the neurometric interface at a first computer system, initiating a request at a second computer system, detecting the initiated request at the second computer system, sending the second signal from the second computer system to the first computer system, receiving the second signal at the first computer system, capturing a snapshot of the first signal, transforming the snapshot of the first signal into a brain state score, and initiating a sequence of events based on the second signal and the brain state score. The first signal is indicative of the brain state. The second signal includes a time that the request was initiated. The snapshot corresponds to the time the request was initiated.
Patent CA-3174472-A1 (CA)
Inventor: SINGH SUKHVINDER
IPC: G06Q10/06
Filed: 2021-03-04
Abstract: Systems and methods for generating and displaying heat maps are provided. A heat map generation computing device includes a memory and a processor. The processor is programmed to receive trap data for a plurality of pest traps in a geographic location, the trap data including current and historical pest pressure values at each of the plurality'' of pest traps, receive weather data for the geographic location, receive image data for the geographic location, apply a machine learning algorithm to generate predicted future pest pressure values at each of the plurality of pest traps, generate a first heat map for a first point in time and a second heat map for a second point in time, and transmit the first and second heat maps to a mobile computing device to cause a user interface on the mobile computing device to display a time lapse heat map.
Patent CA-3179974-A1 (CA)
Inventor: CAINE SOLDO JOSHUA
IPC: C07K16/00
Filed: 2021-04-12
Abstract: The present invention is directed to methods for using particles (e.g, microparticulate, nanoparticulate; magnetic, non-magnetic) comprising surfaces comprising capture moieties as described herein, to remove an interference as described herein, or enrich biomarkers, especially antibodies, prior to a diagnostic test, or to be isolated and used for prophylactic or therapeutic purposes.
Patent CA-3180660-A1 (CA)
Inventor: DOMB ABRAHAM JACOB
IPC: C07C37/66
Filed: 2021-04-21
Abstract: L'invention concerne un matériau isolé, ou une forme phénolate d'au moins un matériau actif contenant du phénol, le matériau isolé comprenant une ou plusieurs espèces phénolate et un contre-ion (un cation) sous la forme d'un sel métallique, d'un phosphonium ou d'un ammonium.
Patent CA-3182890-A1 (CA)
Inventor: MULHERN JAMES
IPC: A61G5/10
Filed: 2021-07-07
Abstract: Un véhicule motorisé peut comprendre un cadre, une roue d'entraînement couplée au cadre, un moteur couplé de manière fonctionnelle à la roue d'entraînement, et un ensemble anti-basculement comprenant une première roue anti-basculement. L'ensemble anti-basculement peut avoir une première configuration dans laquelle la première roue anti-basculement peut pivoter autour d'un axe de pivot par rapport au cadre et se déplacer le long d'un axe de coulissement.
Patent CA-3183948-A1 (CA)
Title: Heteroalkyl dihydroquinoline sulfonamide compounds
Inventor: MILGRAM BENJAMIN C
IPC: A61K31/4704
Filed: 2021-06-11
Abstract: The present invention provides heteroalkyl dihydroquinoline sulfonamide compounds of Formula I, and pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav1.7. The compounds are useful for the treatment of diseases associated with the activity of sodium channels such as pain disorders, cough, and itch. Also provided are pharmaceutical compositions containing compounds of the present invention.
Patent CA-3185047-A1 (CA)
Inventor: WRIGHT ALEC
IPC: A24F40/46
Filed: 2021-07-21
Abstract: An evaporator assembly (101) for an aerosol generating device is described. The evaporator assembly (101) comprises a first body (109) having a first plurality of through-channels (109a), a second body (111) having a second plurality of through- channels (111a), wherein the first body (109) and the second body (111) are arranged such that the first and second plurality of through-channels (109a, 111a) overlap to allow the passage of a liquid from an inlet end (103) to an outlet end (105) of the evaporator assembly (101) through the through-channels (109a, 111a); and a heater arranged to heat the liquid as it passes through the through-channels (109a, 111a), wherein the second body (111) is moveable with respect to the first body (109) such that the area of overlap is adjustable.
Patent CA-3187623-A1 (CA)
Inventor: KAFKA WOLF A
IPC: A61N2/02
Filed: 2021-05-27
Abstract: Dispositif pour influencer des processus biologiques dans un tissu vivant pour appliquer un champ magnétique pulsatoire à au moins une partie du tissu, comprenant un dispositif de génération de champ (2) pour générer le champ magnétique pulsatoire et un générateur d'impulsions (1) pour entraîner le dispositif de génération de champ (2) à l'aide d'une séquence de signaux (13), le générateur d'impulsions (1) étant conçu pour émettre la séquence de signaux (13) qui est formée par superposition d'une première séquence (13a) d'impulsions principales (10a) et d'une seconde séquence (13b) d'impulsions principales (10b) dont la fréquence de récurrence d'impulsion est comprise entre 0,1 et 1 000 Hz, chaque impulsion principale (10a, 10b) présentant une durée d'impulsion, la durée d'impulsion et la fréquence de récurrence d'impulsion des impulsions principales (10b) de la seconde séquence (13b) d'impulsions principales (10b) étant différentes de la durée d'impulsion et de la la fréquence de récurrence d'impulsion des impulsions principales (10a) de la première séquence (13a) d'impulsions principales (10a), la durée d'impulsion des impulsions principales (10b) de la seconde séquence (13b) d'impulsions principales (10b) changeant de manière monotone au fil du temps, et la fréquence de récurrence d'impulsion des impulsions principales (10b) de la seconde séquence (13b) d'impulsions principales (10b) changeant de manière monotone au fil du temps dans la direction opposée au changement de durée d'impulsion.
Patent CA-3190471-A1 (CA)
Inventor: ABRAMS KIMBERLY
IPC: E21C37/18
Filed: 2021-07-30
Abstract: Disclosed are systems and methods to bore or tunnel through various geologies in an autonomous or substantially autonomous manner including one or more non-contact boring elements that direct energy at the bore face to remove material from the bore face through fracture, spallation, and removal of the material. Systems can automatically execute methods to control a set of boring parameters that affect the flux of energy directed at the bore face. Systems can further automatically execute the methods to: monitor, direct, maintain, and/or adjust a set of boring controls, including for example a standoff distance between the system and the bore face, a temperature of exhaust gases directed at the bore face, a removal rate of material from the bore face, and/ or a thermal or topological characterization of the bore face during boring operations.
Patent CA-3192630-A1 (CA)
Title: Formulations stables comprenant un anticorps anti-egfr/c-met bispecifique
Inventor: KUPEC JESSICA
IPC: C07K16/28
Filed: 2021-08-26
Abstract: L'invention concerne des compositions pharmaceutiques aqueuses stables comprenant des formulations d'un anticorps bispécifique anti-récepteur du facteur de croissance épidermique (EGFR)/récepteur du facteur de croissance des hépatocytes (c-Met) et des méthodes pour les préparer. L'invention concerne également des méthodes de traitement du cancer chez un individu en ayant besoin par administration au sujet des compositions pharmaceutiques aqueuses stables divulguées ici. L'invention concerne en outre des kits et des articles manufacturés comprenant les compositions pharmaceutiques aqueuses stables divulguées ici.
Patent CA-3193866-A1 (CA)
Inventor: KYOSTIO-MOORE SIRKKA R M
IPC: C12N15/86
Filed: 2021-09-30
Abstract: Provided herein are expression cassettes for expressing a transgene in a liver cell, wherein the transgene encodes a PAH polypeptide. Also provided are methods to treat phenylketonuria (PKU) and/or to reduce levels of phenylalanine in an individual in need thereof. Further provided herein are vectors (e.g., rAAV vectors), viral particles, pharmaceutical compositions and kits for expressing a PAH polypeptide in an individual in need thereof.
Patent CA-3196749-A1 (CA)
Inventor: SALVATO ANTHONY B
IPC: B65B35/52
Filed: 2021-10-26
Abstract: L'invention concerne un procédé de réalisation d'un système d'emballage multicouche (900), comprenant la fourniture d'une pluralité d'emballages (800), le déplacement de ladite pluralité d'emballages (800) au moyen d'un premier dispositif de déplacement (10), la mise en contact d'un premier groupe d'emballages (810) de ladite pluralité d'emballages (800) dans une zone de collecte (ZP), la collecte, au moyen dudit dispositif de transfert (20) ayant deux degrés de liberté, dudit premier groupe d'emballages (810) et le déplacement dudit dispositif de transfert (20) en fonction d'un composant vertical vers une zone de groupage (ZA) d'un dispositif de groupage (30) pour activer un second élément de retenue (35) dudit dispositif de groupage (30) de manière à collecter ledit premier groupe d'emballages (810), le déplacement à nouveau dudit dispositif de transfert (20) dans ladite zone de collecte (ZP) et le démarrage du déplacement dudit premier dispositif de déplacement (10) de manière à amener un second groupe d'emballages (820) vers ladite zone de collecte (ZP) avant que ledit dispositif de transfert (20) n'arrive dans ladite zone de collecte (ZP), le déplacement dudit dispositif de transfert (20) par mise en contact dudit deuxième groupe d'emballages (820) dans ladite zone de groupage (ZA) de sorte que ledit second groupe d'emballages (820) déplace verticalement ledit premier groupe d'emballages (810) en prenant sa position pour ainsi former ledit système d'emballage multicouche (900).