baber/WOPTO huggingface dataset:
Patent MX-2016014355-A (MX)
Title: Method for selecting antibodies with modified fcrn interaction.
Inventor: HUBERT KETTENBERGER
IPC: C07K16/24
Filed: 2015-06-10
Abstract: Herein is reported a method for selecting a full length antibody comprising the steps of a) generating from a parent full length antibody a plurality of full length antibodies by randomizing one or more amino acid residues selected from the amino acid residues at positions 1-23 in the heavy chain variable domain (numbering according to Kabat), at positions 55-83 in the light chain variable domain (numbering according to Kabat), at positions 145-174 in the first heavy chain constant domain (numbering according to EU index) and at positions 180- 97 in the first heavy chain constant domain (numbering according to EU index), b) determining the binding strength of each of the full length antibodies from the 10 plurality of antibodies to the human neonatal Fc receptor (FcRn), and c) selecting a full length antibody from the plurality of full length antibodies that has a different binding strength to the FcRn than the parent full length antibody.
Patent MX-2016014775-A (MX)
Title: Pharmaceutical use of an extended-release composition containing pirfenidone for the treatment and reversal of human steatohepatitis (nafld/nash).
Inventor: JOSÉ AGUSTÍN ROGELIO MAGAÑA CASTRO
IPC: A61P1/16
Filed: 2016-11-11
Abstract: The present invention relates to the use of a pharmaceutical composition in the form of extended-release tablets containing pirfenidone for the treatment of NAFLD / NASH and advanced liver fibrosis, by reducing serum cholesterol and triglycerides, as well as reducing the content of hepatic fat accumulation, both in the form of macrosteatosis and microsteatosis. The invention also relates to the use of the composition as an agonist for PPARgamma (peroxisome proliferation receptor activated gamma), PPARalpha (peroxisome proliferation receptor activated alpha), LXR and CPT1, key molecules in the metabolism of fatty degradation and inflammation of the liver. In addition, another use is the induction of decreased expression of the NFkB master gene, transcriptional inducer of hepatic inflammatory process factor. All of these events result in the reversal of NAFLD / NASH and advanced liver fibrosis.
Patent MX-2016015417-A (MX)
Title: Multiparticles safeguarded against ethanolic dose-dumping.
Inventor: LUTZ BARNSCHEID
IPC: A61K31/135
Filed: 2015-05-22
Abstract: The invention relates to an oral pharmaceutical dosage form providing resistance against dose dumping in aqueous ethanol and comprising a pharmacologically active ingredient embedded in a matrix material, wherein the matrix material comprises an alkyl cellulose and a heteropolysaccharide; and wherein the relative weight ratio of heteropolysaccharide to alkyl cellulose is within the range of from 1 : 20 to 20 : 1; and wherein the total content of alkyl cellulose and heteropolysaccharide is at least 35 wt.-%, relative to the total weight of the dosage form.
Patent MX-2016015542-A (MX)
Title: Configurable support system for loads requiring vibration isolation.
Inventor: CARLOS TÉLLEZ MARTÍNEZ
IPC: E04B1/98
Filed: 2016-11-25
Abstract: The present invention relates to a configurable system for isolating low-frequency vibration to objects or people placed on top of the system. It aims to modify the height and the required area depending on the isolation needs of the vibration or the load capacity. Also, it aims to use the configurable system as a false floor for the damping of impacts or the separation of vibration in humans, thereby avoiding health problems.
Patent MX-2016015797-A (MX)
Title: Apparatus, system and method for dedicated core network.
Inventor: TOSHIYUKI TAMURA
IPC: H04W60/00
Filed: 2015-05-26
Abstract: In order for more effectively supporting a Dedicated Core Network, there is provided a network system including a first node (30) that establishes secure connection with a UE (10) initially attempting to attach to a network, through a radio base station (20), and a second node (40) to which the UE (10) is redirected from the first node (30) through the radio base station (20). Upon the redirection, the first node (30) sends information on the first node (30) itself to the second node (40) through the radio base station (20). The second node (40) uses the information to retrieve security context necessary for establishing the connection with the UE (10) from the first node (30).
Patent MX-2017002073-A (MX)
Title: Esterified cellulose ethers of low acetone-insoluble content.
Inventor: OLIVER PETERMANN
IPC: A61K47/38
Filed: 2015-08-18
Abstract: Esterified cellulose ethers which have i) as ester groups aliphatic monovalent acyl groups or groups of the formula - C(O) - R - COOA or a combination of aliphatic monovalent acyl groups and groups of the formula -C(O) - R - COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, and ii) a content of not more than 0.85 weight percent acetone-insoluble esterified cellulose ether particles, when the esterified cellulose ether is present in a mixture of 12.5 weight parts of esterified cellulose ether and 87.5 weight parts of acetone at 21 °C, the weight percent acetone-insoluble esterified cellulose ether particles being based on the total weight of the esterified cellulose ether, wherein iii) not more than 14 percent of the acetone-insoluble esterified cellulose ether particles have a particle size of more than 90 micrometers.
Patent MX-2017002674-A (MX)
Title: Antibody therapeutics that bind oprf and oprl.
Inventor: HEYUE ZHOU
IPC: A61K39/104
Filed: 2015-08-28
Abstract: There is disclosed compositions and methods relating to or derived from anti-OprF and anti-Oprl antibodies. More specifically, there is disclosed fully human antibodies that bind OprF and Oprl, OprF and Oprl-antibody binding fragments and derivatives of such antibodies, and OprF and Oprl-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having Pseudomonas aeruginosa infections. There is disclosed a method for treating or preventing Pseudomonas aeruginosa infections, wherein the disease is selected from the group consisting of burns, surgical site infections, diabetic foot ulcers, infected wounds, and cystic fibrosis.
Patent MX-2017005013-A (MX)
Title: Method of management of splitting the information object stored in a single database.
Inventor: ODEY HALIKOVICH DERUT
IPC: G06F17/30
Filed: 2015-10-22
Abstract: The invention relates to the method of automated management of splitting the information objects stored in a single database into individual pieces. The method of automated management of splitting the information objects stored in a single database comprises: creating a metadata object, the "shared attribute; setting the "shared object" parameters; setting the metadata object named "session parameters" that stores tenant and/or tenant group IDs along with the current delimiter value; identifying specific tenants and defining the current values for each delimiter metadata object; assigning an isolated data area containing metadata objects with an added "shared attribute" to each tenant; writing the "shared attribute" value into a corresponding column when writing data into split information objects with the "shared attribute" metadata object; generating queries to obtain data from the data areas assigned to a tenant. The delimiter references the split information objects and provides both complete and partial data splitting. ï»¿.
Patent MX-2017006201-A (MX)
Title: Predicting response to a vegf antagonist.
Inventor: YUANYUAN XIAO
IPC: A61K31/337
Filed: 2015-11-09
Abstract: The invention describes the use of high CD31 and/or tumor VEGFA as selection criteria for determining patient benefit or responsiveness to a VEGF antagonist, such as bevacizumab. The present invention also describes the use of high CD31 and/or tumor VEGFA as a selection criterion for treating cancer patients, such as ovarian cancer patients, who are undergoing a chemotherapy and/or anti-cancer therapy regimen, with a VEGF antagonist, such as bevacizumab.
Patent MX-2017011579-A (MX)
Title: Heterocycle-substituted bicyclic azole pesticides.
Inventor: WENMING ZHANG
IPC: C07D407/14
Filed: 2016-03-03
Abstract: Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein Q is Q-1, Q-2, Q-3 or Q-4 and A, R1, m, X1, X2, X3, X4, Y1, Y2 and Y3 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.
Patent MX-2017014026-A (MX)
Title: System and method for data synchronization.
Inventor: RAVI AYYASAMY
IPC: H04W4/10
Filed: 2016-05-06
Abstract: An embodiment includes receiving, by a client on a client device, a data change notification. The data change notification indicates a change in data relating to the client at a client data store. The method further includes determining, by the client, a type of the data relating to the client changed at the client data store and determining, by the client, a data synchronization mechanism in accordance with the type of the data relating to the client changed at the client data store. Determining the data synchronization mechanism includes determining when to attempt, by the client, a data synchronization to synchronize data on the client device with the data relating to the client changed at the client data store.
Patent MX-2017014810-A (MX)
Title: Anti-cd38 antibodies for treatment of light chain amyloidosis and other cd38-positive hematological malignancies.
Inventor: PARUL DOSHI
IPC: C12N15/13
Filed: 2016-05-20
Abstract: The present invention relates to combination therapies with anti-CD38 antibodies and all-trans retinoic acid.
Patent MX-2017014878-A (MX)
Title: Threaded coupling end for a percussion drill string component.
Inventor: David WICKSTRÖM
IPC: E21B17/042
Filed: 2016-05-19
Abstract: A threaded coupling for a drill string component having a body on which is formed a thread. A reduction in stress concentrations and a resistance to bending moments are achieved at the thread by reducing a thread depth at at least one axial end (300) of the thread and by adapting an endmost flank of a crest or root of the thread at an endmost helical turn.
Patent MX-2017015434-A (MX)
Title: Waterborne coating composition.
Inventor: JOVAN L THOMPSON
IPC: C08G18/75
Filed: 2016-06-01
Abstract: In one embodiment, a single component waterborne coating composition includes water; a branched polyester polyurethane dispersion; a polycarbonate polyurethane dispersion blend including a branched polycarbonate PUD and an unbranched, hydroxyl functional, polycarbonate polyurethane dispersion; and a fluorinated acrylic latex resin. In another embodiment, the fluorinated acrylic latex resin may be replaced with a hybrid resin selected from the group consisting of a fluorinated acrylic and polyester polyurethane dispersion hybrid resin and a fluorinated acrylic and polycarbonate polyurethane dispersion hybrid resin.
Patent MX-2017017001-A (MX)
Title: Food product package.
Inventor: PAOLO VACCARELLA
IPC: A23G1/54
Filed: 2016-06-30
Abstract: Package for a food product comprising an openable container (1) of non-edible material, including in its interior an accessory which is formed by a first (2) and a second (4) half-shell, connected together by mutual engagement means (6), and a single half-shell of edible material (8) or a plurality of half-shells of edible material provided that they are overlapping, associated with only one (2) of the half-shells of said container, the inner surface (20) of said half-shell (8) of edible material or of the innermost of said half-shells of edible material being of a shape substantially corresponding to the outer surface (24) of the half-shell (2) of non-edible material associated therewith, characterized in that the outer surface (30) of said half-shell of edible material (8) and the outer surface of the other half-shell (4) of the container jointly form a symmetrical body with respect to the coupling plane of the respective half-shells, or a symmetrical body with respect to a plane of symmetry of said body perpendicular to the coupling plane.
Patent MX-2018003715-A (MX)
Title: System for quick coupling and uncoupling of a tracked unit with respect to a chassis of a tracked machine, particularly a tracked pipe laying machine.
Inventor: FERNANDO PICCININI
IPC: B66C23/36
Filed: 2016-09-21
Abstract: A system (1) for quick coupling and uncoupling of a tracked unit (2) with respect to a chassis (3) of a tracked machine (4), particularly a tracked pipe laying machine, which comprises: - at least two supporting structures (5), configured to be associated with a chassis (3) of a tracked machine (4), wherein each one of the two supporting structures (5) comprises at least one fixed pin (7) and at least one pin (8) that can move axially along its own longitudinal axis, - at least two coupling devices (6), configured to be associated with a tracked unit (2), wherein each coupling device (6) comprises at least one hook (9) and at least one slot (10). In a configuration for coupling the tracked unit (2) to the chassis (3), the hook (9) is mated with the fixed pin (7) and the movable pin (8) is inserted in the slot (10). The quick coupling and uncoupling system (1) comprises an actuator (11) that is connected to the movable pin (8) in order to produce its axial movement. The actuator (11) is arranged laterally to the movable pin (8).
Patent MX-2018005757-A (MX)
Title: Transfer or shoe press belt for a paper machine, use of the belt in a paper machine and method for producing the belt.
Inventor: DIRK PRASCHAK
IPC: D21F11/00
Filed: 2018-05-08
Abstract: The invention relates to a transfer or shoe press belt with a paper side (1) intended for supporting a paper or felt web and a machine side (2) facing away from the paper side, and with a carrier (3) and a paper side and / or machine side of the carrier (3) arranged structured cover layer (4), which consists of at least one polymer, in particular polyurea and / or polyurethane coating material or existing therefrom and at least on their side facing away from the carrier (3) side by a structured surface having a plurality characterized by elevations (5) and depressions (6) and is ground on its side remote from the carrier (3) side. Moreover, the invention relates to a method for producing a transfer or shoe press belt and the use of such as a press belt, in particular transfer or shoe press belt, in a paper machine.
Patent MX-2018006876-A (MX)
Title: Cutting head assembly.
Inventor: KOON FOR CHUNG
IPC: A01G3/00
Filed: 2018-06-06
Abstract: A cutting head assembly, a trimmer head and a power tool including such cutting head assembly. The cutting head assembly comprises a spool and an enclosure combined to define a spool cavity arranged to accommodate a trimmer line wound on the spool, characterized in that the trimmer line is arranged to form a single layer of winding when being retracted within the enclosure.
Patent MX-2018007610-A (MX)
Title: Fabric softener active compositions.
Inventor: BLANCA NOGUÉS LÓPEZ
IPC: C11D3/37
Filed: 2018-06-20
Abstract: The present invention relates to fabric softener active compositions comprising a combination of a mixture of quarternary ester ammonium compounds and fatty solvents ( a fatty acid ester, a fatty acid, a fatty alcohol and mixtures thereof) and methods of making and using the same. The fabric softener active compositions preferably comprise component (a), said component being a mixture of quarternary ester ammonium compounds obtained by esterification of a mixture of alkanolamines comprises at least a trialkanolamine and a monoalkyldialkanolamine; component (b), said component being a fatty acid ester or a mixture of fatty acid esters, wherein the component (b) content is in the range from 5 to 60% wt. based on the total weight of the fabric softener active composition; and a component (c), said component being a fatty acid or a mixture of fatty acids, wherein the component (c) content is in the range from 0 to 15% wt. based on the total weight of the fabric softener active composition. The invention also proposes fabric softener compositions, comprising the previously described active compositions, and methods of making and using the same.
Patent MX-2018007818-A (MX)
Title: Novel anti-upk1b antibodies and methods of use.
Inventor: ROBERT A STULL
IPC: A61P35/00
Filed: 2016-12-21
Abstract: Provided are novel anti-UPK1B antibodies and antibody drug conjugates, and methods of using such anti-UPK1B antibodies and antibody drug conjugates to treat cancer.
Patent MX-2018008954-A (MX)
Title: COMPOSITIONS COMPRISING 2FL AND LNnT TO CONTROL FOOD INTAKE AND GROWTH IN INFANTS OR YOUNG CHILDREN.
Inventor: LAURENT FAVRE
IPC: A23L33/00
Filed: 2017-01-26
Abstract: The present invention relates to a nutritional composition comprising at least one fucosylated oligosaccharide and at least one N-acetylated oligosaccharide,for use in reducing and/or controlling food intake in an infant or a young child, and/or for use in promoting a healthy growth in an infant or a young child.
Patent MX-2018012861-A (MX)
Title: Post mix nozzle design.
Inventor: WILLIAM E DENNISON
IPC: F23D14/54
Filed: 2017-04-20
Abstract: A cutting nozzle assembly and associated method of making same includes a nozzle having a central bore extending therethrough along a longitudinal axis through which an associated cutting gas is discharged. A plurality of spaced fuel gas bores are arranged around the central bore, and preheat passages are arranged around both the central bore and the fuel gas bores. A retaining nut receives at least a portion of the nozzle therein, and the retaining nut includes a shroud extending axially outward from a discharge end of the nozzle. At least one of an inner surface of the shroud and the additional preheat passages are angled inwardly toward the longitudinal axis. The fuel gas bores and the preheat passages each have the same cross-sectional dimension, and twice the number of preheat passages as fuel gas bores are provided.
Patent MX-2019000101-A (MX)
Title: Collecting user information from computer systems.
Inventor: HUI LI
IPC: G06F16/00
Filed: 2017-07-07
Abstract: Textual information related to user information from user service information is identified. A layered matching is performed on the textual information based on preset background identification information in a preset list, wherein the layered matching includes different matching methods, and the preset list includes a plurality of entries storing different preset background identification information related to the user information. The user information is determined based on the layered matching.
Patent MX-2019004754-A (MX)
Title: Adaptive braking for a vehicle control system.
Inventor: ANDREW L KENNEDY
IPC: B60W30/08
Filed: 2017-10-20
Abstract: A controller (24) for an adaptive braking system on a host vehicle identifies a first target (42) in a lane of travel of the host vehicle; monitors for an active braking intervention request; monitors for other targets (44) in adjacent lanes of travel to the host vehicle (40); and transmits a first braking signal at the output to control a braking action at a first braking level in response to receiving the active braking intervention request and identifying no other targets in adjacent lanes of travel to the host vehicle. If the controller identifies a second target in an adjacent lane of travel, then receives a travel signal indicative of change in the direction of travel of the host vehicle toward the second target; it will transmit a second braking signal to control the braking action at a second braking level. The second level of braking is different than the first level of braking.
Patent MX-2019007035-A (MX)
Title: Cable having shielding tape with conductive shielding segments.
Inventor: SCOTT M BROWN
IPC: H01B7/02
Filed: 2019-06-13
Abstract: A cable includes a first twisted pair of insulated conductors, a second twisted pair of insulated conductors, a shielding tape, and an outer jacket surrounding the first twisted pair of insulated conductors, the second twisted pair of insulated conductors and the shielding tape. The shielding tape includes a substrate and a plurality of conductive shielding segments. The plurality of conductive shielding segments is disposed on the substrate. Each conductive shielding segment is spaced from each immediately adjacent conductive shielding segment in a longitudinal direction.
Patent MX-2019007563-A (MX)
Title: Methods for minimizing delayed effects of exposure to reduced oxygen partial pressure via administration of supplemental oxygen.
Inventor: JOHN J KELLY
IPC: A62B7/14
Filed: 2017-12-22
Abstract: Described herein are methods which involve minimizing or eliminating the occurrence of delayed negative effects that may arise from exposure to reduced oxygen partial pressure. An amount of supplemental oxygen, which substantially mimics a target oxygen partial pressure, is administered to an individual that is exposed to a reduced oxygen partial pressure environment, to compensate for the reduced oxygen partial pressure. The target partial pressure may be selected such that the individual experiences substantially no change in the oxygen partial pressure. Individuals receiving the supplemental oxygen may be healthy, have special sensitivities, or have a pre-existing neurological condition.
Patent MX-2019015592-A (MX)
Title: User device, communication control method for user device, core network device, communication control method for core network, smf, and communication control method for smf.
Inventor: YUDAI KAWASAKI
IPC: H04W76/18
Filed: 2018-06-19
Abstract: In the present invention, devices such as a terminal device and a device in a core network exchange capability information for each function in a registration procedure and a PDU session establishment procedure, control of terminal device-led RQoS is achieved by adding additional information to an uplink packet in user data communication, and control of network device-led RQoS is achieved by adding additional information to a downlink packet. In addition, an authentication approval function by DN is achieved by defining a dedicated control message and information for the authentication approval function by DN. Furthermore, management processing such as congestion management for each network slice is achieved by equipping the devices such as a terminal device and a device in a core network with control processing and a timer for each network slice. As a result, the present invention provides a communication control method for achieving the following: control of terminal device-led RQoS and control of network-led RQoS; an authentication approval function by DN; and management processing such as congestion management for each network slice.