baber/WOPTO huggingface dataset:
Patent EP-1007630-B1 (EP)
Inventor: KLINGEMANN HANS
IPC: A61K35/12
Filed: 1998-04-30
Granted: 2006-04-19
Abstract: The invention relates to a natural killer cell line termed NK-92. The invention provides a vector for transfecting a mammalian cell which includes a nucleic acid sequence encoding a cytokine that promotes the growth of NK-92. Additionally, the invention provides an NK-92 cell, or an NK-92 cell modified by transfection with a vector conferring advantageous properties, which is unable to proliferate and which preserves effective cytotoxic activity. The invention further provides a modified NK-92 cell that is transfected with a vector encoding a cytokine that promotes the growth of NK-92 cells. The cell secretes the cytokine upon being cultured under conditions that promote cytokine secretion, and furthermore secretes the cytokine in vivo upon being introduced into a mammal. In a significant embodiment, the cytokine is interleukin 2. The present invention also provides methods of purging cancer cells from a biological sample, of treating a cancer ex vivo in a mammal, and of treating a cancer in vivo in a mammal employing a natural killer cell, such as NK-92 itself, an NK-92 cell which is unable to proliferate and which preserves effective cytotoxic activity, or natural killer cells transfected with a vector encoding a cytokine.
Patent EP-0910486-B1 (EP)
Inventor: SPAETH WALTER E
IPC: B21D7/08
Filed: 1998-04-23
Granted: 2003-10-22
Abstract: The invention relates to a method and multistation device for folding profiles. The folding stations (1, 11, 15, 16, 17) required are modules mounted interchangeable and adjustable on a common machine body (2), which permits quick and simple adaption to the folding requirements. It is thus possible, with one single machine, to implement a whole series of folding processes. With regard to the machine operation, such stations are selected as needed, fitted and set depending on folding criterion.
Patent EP-1062198-B1 (EP)
Inventor: LEE BON-SU
IPC: C07C205/06
Filed: 1998-09-18
Granted: 2003-06-04
Abstract: The nitration of aromatic compounds is achieved in high yield and selectivity by using oxygen activated by an inorganic catalyst and nitrogen dioxide. Since this process uses neither concentration nitric nor sulfuric acids, the generation of spent waste acid does not occur. Furthermore, the process does not encounter the problem of high costs associated with the generation of ozone as in an alternative nitration process. Since the solubility of oxygen in a reaction medium is increased by using pressurized oxygen, nitrogen dioxide is activated by a porous inorganic oxide and thus an aromatic compound(e.g., benzene) is nitrated into a nitro compound (e.g., PhNO2), the reaction rate is significantly increased, and the recovery of reactants is easy due to the insolubility of the catalyst.
Patent EP-1027511-B1 (EP)
Inventor: BUZON CLAUDE
IPC: E04D11/00
Filed: 1998-10-30
Granted: 2004-10-27
Abstract: A device for adjusting the inclination of a building surface, the device having two mutually cop-operating adjusting elements. The first element is for establishing an initial angle alpha and the second adjusting element is moved between an initial position and operational position selected by the user depending on the slope to be given to the building surface. The second adjusting element is selectively adjustable relative to the first adjusting element and thereby produces the slope required for the building surface by positioning the second element with respect to the first by mutual rotation. The device also has an adjusting means for making each mutual position corresponding to an adjusting angle alpha.
Patent EP-1032258-B1 (EP)
Inventor: GUBBELS HENRICUS ANTHONIUS
IPC: F24F1/0038
Filed: 1998-11-19
Granted: 2002-02-13
Abstract: The invention relates to a stable comprising a floor, upright walls bounding said floor, in which walls one or more fans are present, and a roof covering a space bounded by said floor and said walls, in which roof means for exhausting spent air are present, which spent air is used for controlling the temperature of the air to be supplied, wherein said fans supply conditioned air essentially at floor level, wherein the amount of air to be supplied and the temperature thereof can be controlled for each fan individually.
Patent EP-0981102-B1 (EP)
Inventor: SCHMIDT ANDREAS
IPC: G06K7/00
Filed: 1999-01-14
Granted: 2002-09-18
Abstract: The device has a transmit memory (14) storing a query data sequence from the data transfer protocol for each type of transponder, to initiate communication. Receiver memory stores expected reply data sequences for each type of transponder. Sender unit transmits stored query data sequence assigned by protocol to one type of transponder and then for different type of transponder. A sender unit (20) sends stored query data sequence for a transponder type to determine if that type of transponder is in vicinity of device (10), If the transponder type is present, transponder sends reply data sequence to be evaluated by evaluation electronics (12) as received answer data sequence. If transponder answers which is not type addressed, then received reply data sequence is compared with expected answer data sequence to determine if valid reply data sequence. If there is no transponder of first type, sender (14) transmits query data sequence for second transponder type. Both transponders have common carrier frequency 13.56 MHz. An Independent claim is included for the reading and writing process for the transponders.
Patent EP-0972457-B1 (EP)
Inventor: PASSI GERALD
IPC: A63B71/12
Filed: 1999-06-25
Granted: 2003-08-20
Abstract: The protector consists of a flexible inner member at least partially covering the part of the body being protected, an outer rigid shell and fasteners (61, 62, 63). The shell is in two or more sections (40, 41) connected by hinges (42) which can be adjusted before fixing with locking elements (5) in the form of straps with buckles or Velcro (RTM) strips. The hinges can be made by zones of reduced thickness.
Patent EP-0989597-B1 (EP)
Inventor: HACKETT THOMAS B
IPC: C09K13/04
Filed: 1999-08-27
Granted: 2003-11-12
Abstract: The invention relates to an aqueous phosphoric acid etch bath composition with a readily soluble silicon containing composition. The baths are used in the etching step of composite semiconductor device manufacturing.
Patent EP-1092830-B1 (EP)
Inventor: GUTER AUGUST
IPC: E06B3/70
Filed: 1999-10-15
Granted: 2003-06-04
Abstract: The gate system (10), to close a wall opening, has a frame for a moving gate panel. The gate panel has two spaced and parallel covering boards (12,13), with intermediate honeycombs (11) between them where their total cross section surfaces match the base surface. The honeycombs are identical in triangles, quadrilaterals or hexagons with surface areas of 1-9 cm<2>, and in a height of 2-8 cm. The boards are compressed chipboards or nautical plywood, glued cardboard, of metal or plastics. The honeycombs are of glued recycled paper/cardboard materials.
Patent EP-1048952-B1 (EP)
Inventor: HOUTSMULLER ADRIAAN BAREND
IPC: G01N33/50
Filed: 1999-04-29
Granted: 2003-03-26
Abstract: The invention relates to the field of measuring or determining mobilities of analytes or molecule(complexes). The invention provides a method for determining the mobility of a certain analyte in a set volume comprising labelling said analyte with a laser-inducible moiety and subjecting a spot or area in a pre-determined plane through said set volume to a focused laser beam of relatively low intensity for a relatively long time thereby inducing a measurable change in said moiety when exposed to said laser beam and determining the distribution of laser-exposed moiety in said plane.
Patent EP-1063177-B1 (EP)
Inventor: KEIZER CORNELIS
IPC: A23L17/50
Filed: 1999-06-24
Granted: 2008-02-13
Abstract: A method to prolong time-until-death during storage of alive bivalves, by periodically forcing the animals in a first step of a cycle of at least two steps to abruptly adopt an anaerobic metabolism by either: 
- exposure to (sea-)water, and simultaneously imposing a physical and/or a chemical threat; or 
- alternatively in a first step by exposure to dry conditions  
and in the second step to abruptly adopt an aerobic metabolism by exposure to wet conditions.
Patent EP-0984649-B1 (EP)
Inventor: CHENG TERRY SI-FONT
IPC: H04B7/26
Filed: 1999-08-10
Granted: 2006-12-27
Abstract: A procedure for triggering a handdown or a handoff a mobile station served by a base station of a cellular wireless communication system. A tolerable path loss for signal links between the base station and a mobile station located within the base station's cell, is initially determined. A control signal is radiated at a known transmit power level from the base station over its cell. A receive power level threshold is determined for the control signal for reception by the mobile station, according to the transmit power level and the tolerable path loss. A handoff of the mobile station is triggered after deriving the received power level of the control signal at the mobile station, and determining that the received power level is less than the receive power level threshold. In one embodiment, a mobile station reports to a serving base station only after the former determines that the received power level of a control signal from the base station is less than a threshold level initially provided to the mobile station by the base station. The procedure is applicable, e.g., to base station cells of a first CDMA cellular system which cells border on cells of an analog (AMPS) or a second CDMA cellular system.
Patent EP-1056650-B1 (EP)
Inventor: OSTERGAARD-NIELSEN MOGENS
IPC: B65D51/22
Filed: 1999-02-17
Granted: 2003-01-22
Abstract: A plastics pour spout fitment (3) has not only a pour spour (4) thereof welded to plastics-coated paperboard packaging material (2), but also has a plunger (14) welded to a disc (8) of the material (2), the disc (8) being defined by a ring of weakening (6) in the material. Following purely linearly axially inward displacement of the plunger (14) relative to the pour spout (4), preferably followed by rotation of the plunger (14) about the axis A of the fitment (3) relative to the spout (4), to detach the disc (8) from the remainder of the material (2), the plunger (14), and thus the disc (8), are removed from the pour spout (4) as a screw cap (12) is removed from the spout (4).
Patent EP-1051541-B1 (EP)
Inventor: HERRMANN SIGRID
IPC: C25D21/18
Filed: 1999-02-05
Granted: 2001-11-28
Abstract: The invention relates to a method for electrically regenerating rhodium solutions, designed especially for regenerating rhodium solutions containing sulphuric acid and/or phosphoric acid or rhodium chloride solutions. The solution to be regenerated is introduced in the anode area (12) of an electrolytic cell (10), which is separated from the associated cathode area (14) by an ion exchange membrane (16), said cathode area being filled with a dilute acid having a good conductivity. The rhodium solution pH is increased so as to reach a value greater than 10, preferably in the range from 10 to 14, by adding an alkaline solution, i.e. a concentrated hydroxide potassium solution. Electrolysis is carried out at electric densities that are so high that the trivalent rhodium of the rhodium solution is oxidised to form an hexavalent rhodium, and possible impurities are depleted by the ion exchange membrane (16) in the catholytes. Hexavalent rhodium is transferred in the cathode area at a speed slightly smaller than trivalent rhodium, and therefore no noticeable rhodium depletion can be observed. This is particularly true when pH during electrolysis is maintained at a value permanently greater than 1.5 by means of proper addition of alkaline solution.
Patent EP-1069996-B1 (EP)
Inventor: SERGEL HORST
IPC: B60C17/04
Filed: 1999-03-11
Granted: 2002-07-03
Abstract: The tire sidewalls have bead areas (6) which are held in annular chambers (10), the axially outer walls (23) of which have an opening (24) to enable the sidewalls (9) to pass through. Each bead is held in a cylindrical axially inner area of each chamber and the sidewall in an axially outer area whose breadth increases to the outside of the rim. A filling ring (12) with a radially inner surface corresponding to the radially inner chamber wall (20) is pressed against the latter when the tire is mounted. Preferred Features: The filling rings (12) move axially to hold and/or allow removal of the tire beads from the rim (1) and when correctly positioned extend axially out through the openings (24) in the axially outer chamber walls (23). Filling ring construction comprises rubberized cords spirally wound around the ring axis. The radially inner and outer faces of a filling ring are parallel and when the ring is correctly located forms a positive connection with the radially inner side of the bead (6). The outer side of the bead lies against the radially outer wall of the annular chamber (10). In a design variation the axially outer area of the chamber may extend into a third axial area. Both areas may be curved and the radially inner wall has a nose which radially narrows the chamber. The ratio of the maximum radius of the radially inner chamber wall (20) in the broadening axially outer area to the radius of the inner chamber wall in the cylindrical axially inner area is 1.005-1.4. The radially outer surfaces of the rim act as an emergency running face. Tire beads may be coreless or have a rubber core (8) with a hardness of 80-100, preferably 85-90 Shore A. The bead core may have an extension of 5-30%, preferably 10-20% and a compressibility of 1-5%, preferably 2.5-3.5%. The maximum diameter of the emergency running surfaces is 1.05-1.3 times, preferably 1.1-1.2 times greater than the inner ring diameter of the bead core when the wheel is assembled.
Patent EP-1065947-B1 (EP)
Inventor: BOZA JULIO
IPC: A23L33/175
Filed: 1999-02-22
Granted: 2003-04-23
Abstract: A method of providing glutamine to a patient. A nutritional composition which includes whey protein, or a protein mixture which simulates the amino acid profile of whey protein, as a protein source is enterally administered to the patient. The whey protein may be a hydrolyzed whey protein. The patient may be a stressed patient, pre-term baby, or athlete.
Patent EP-1115471-B1 (EP)
Inventor: CAMPBELL LARRY E
IPC: B01J23/56
Filed: 1999-06-16
Granted: 2009-10-07
Abstract: A system for treating the exhaust of an industrial process or combustion source to remove gaseous sulfur compounds which includes contacting the exhaust containing gaseous sulfur compounds with a catalytic system of a structured support for example a monolith coated with: (i) a metal oxide sorber component selected from the group consisting of Ti, Zr, Hf, Ce, Al, Si and mixtures thereof, for example TiO2 (ii) a precious metal component, for example Pt metal and optionally (iii) a modifier consisting of an oxide Ag, Cu, Bi, Sb, Sn, As, In, Pb, Au or mixtures thereof, such as Cu as a compound. The system captures the gaseous sulfur compounds. Gaseous sulfur compounds are then driven off as mainly H2S and SO2 in higher concentrations in a separate isolated lower flow stream. The higher concentrations are easier to process to less noxious or useful sulfur materials and the catalyst/sorber is regenerated. The system also removes carbon monoxide by the oxidation of the carbon monoxide to carbon dioxide.
Patent EP-1080615-B1 (EP)
Inventor: STELZL ALOIS
IPC: H05K3/24
Filed: 1999-05-03
Granted: 2002-02-13
Abstract: L'invention concerne un flan imprimé multiple (1) pouvant être individualisé en flans imprimés individuels (2) pour des composants électroniques (3), notamment des composants à ondes de surface acoustiques, qui sont adaptés pour la mise en contact de puces par connexion par billes sur les flans imprimés individuels (2) et pour la mise en contact des flans imprimés individuels (2) selon la technique du montage en surface avec des connexions extérieures. Dans ce flan imprimé multiple (1), chaque flan imprimé individuel (2) présente des surfaces métallisées (5) qui se trouvent sur un système de réseau intégré dans le flan imprimé multiple et mènent à un pôle de connexion (8). La réalisation de bosses (13) s'effectue par dépôt par voie galvanique de métal sur les surfaces métallisées (5).
Patent EP-1095062-B1 (EP)
Inventor: NICKOLOFF BRIAN J
IPC: C12Q1/68
Filed: 1999-06-28
Granted: 2006-09-13
Abstract: Methods of treating psoriasis and other cutaneous and extracutaneous disorders mediated by immunocytes bearing natural killer-type receptors (NK-T cells) for classical or non-classical MHC-class I-like molecules (and their functional homologs). The methods of the present invention include antagonizing the activation mediated by NK-type receptors for those diseases in which such immunocytes are causing or exarcebating the disease, as well as for methods to augment the immune response in infectious (viral, bacterial, or fungal) or neoplastic conditions in which such activation would be beneficial.
Patent EP-1105102-B1 (EP)
Inventor: ALEMAN CLAUDE
IPC: A61K47/14
Filed: 1999-08-18
Granted: 2003-01-02
Abstract: The invention concerns an aqueous pharmaceutical composition containing a lyophilisate consisting of clopidogrel or ticlopidin optionally in the form of a pharmaceutically acceptable salt, of Pluronic F683reconstituted in a recovery solvent comprising a basic pH modifying agent compatible with parenteral administration and Solutol HS153.
Patent EP-1090029-B1 (EP)
Inventor: SCHWARZ SIGFRID
IPC: C07J53/00
Filed: 1999-06-18
Granted: 2002-03-20
Abstract: Described are new 14,15-cyclopropano steroids of the 19-norandrostane series of general formula (I) and their pharmaceutically acceptable salts, a process for their production and pharmaceutical preparations that contain these compounds. The compounds are distinguished by hormonal (gestagenic and/or androgenic) activity.
Patent EP-1105423-B1 (EP)
Inventor: KLEESIEK KNUT
IPC: C12Q1/68
Filed: 1999-08-18
Granted: 2004-06-16
Abstract: The invention relates to a novel mutant of tissue factor pathway inhibitor (TFPI) protein and its corresponding DNA sequence. The mutant can be found in humans who show or may show an increased risk of thrombotic diseases. By screening samples of human blood for said DNA or fragments of it, it is possible to predict a disposition of thrombotic disorders by which prophylactic application or measures can be initiated.
Patent EP-1119486-B1 (EP)
Inventor: AARNIVUO JUSSI
IPC: B63H25/42
Filed: 1999-09-13
Granted: 2004-12-01
Abstract: The present invention relates to a propeller drive arrangement and a method for moving and steering a vessel. The arrangement comprises an azimuthing propulsion unit and operating equipment for turning said azimuthing propulsion unit to steer the vessel. The operating equipment comprises an electric motor for rotating said propulsion unit by means of a mechanical power transmission machinery connected to said electric motor. A power unit supplies electric power to said electric motor. A control unit controls the operation of said electric motor by controlling said power unit. The arrangement also comprises a sensor device for detecting the rotational position of said azimuthing propulsion unit. A control unit is arranged to process steering command information from a control means and turning position information from said sensor device and to control the operation of said electric motor on the basis of this processing.
Patent EP-1121043-B1 (EP)
Inventor: THOMSON ANDREW WALTER MCRAE
IPC: A47L5/32
Filed: 1999-10-04
Granted: 2002-12-18
Abstract: A changeover valve comprises a first valve member and a second valve member. The first value member has an aperture. The second valve member has first and second apertures. The first valve member is movable relative to the second valve member for selective alignment of the first value member aperture with one or other of the apertures of the second valve member. The value also has a ramp and follower means for automatically moving the valve member away from the one another during changeover movement of the first valve member relative to the second valve member so that wear on the surfaces of the valve members is minimized.
Patent EP-1123513-B1 (EP)
Inventor: TRUEBENBACH ERIC L
IPC: G01R31/00
Filed: 1999-10-14
Granted: 2008-12-10
Abstract: Analog test instrument architecture for performing functional testing of electronic circuit assemblies is disclosed. The analog test instrument includes a plurality of identical channels, each channel including circuitry for driving test stimuli and measuring responses at one node of a circuit assembly under test. The driver and measurement circuitry in each channel implement functions that traditionally have been implemented in a test system using discrete instruments. The analog test instrument further includes a master clock reference, which is used for synchronizing the operation of the driver and measurement circuits. Each channel further includes triggering circuitry for distributing trigger events within the channel and to the other channels; and, an input buffer, which is shared by the measurement circuits in the channel. The synchronized operation, distributed trigger events, and shared input buffers are used to improve the correlation of measurements made during functional testing.
Patent EP-1131298-B1 (EP)
Inventor: MAYWALD VOLKER
IPC: C07D231/20
Filed: 1999-11-06
Granted: 2003-09-03
Abstract: Procédé de préparation de 5-hydroxypyrazoles substitués en position 1, de formule (I) dans laquelle R1 représente alkyle C¿1?-C6, alcényle C2-C6, alcinyle C2-C6, cycloalkyle C3-C6 ou alcoxy C1-C4, ces groupes pouvant être substitués par halogène, alcoxy C1-C4, phénoxy, alcoxycarbonyle C1-C6, alkylthiocarbonyle C1-C6 ou un système de noyau cyclique ayant 3 à 14 atomes sur le noyau, qui consiste à faire réagir (a) un alkylvinyléther de formule générale (III), dans laquelle R?2¿ représente alkyle C¿1?-C6 ou cycloalkyle C3-C6, avec du phosgène (IVa), du 'diphosgène' (IVb) ou du 'triphosgène' (IVc) pour obtenir des chlorures d'acide de formule (V), (b) à transformer ces chlorures d'acides par élimination du gaz chlorhydrique en chlorure d'acide 3-alcoxyacrylique de formule (VI) et (c) à faire réagir ce chlorure avec des hydrazines de formule (VII) dans laquelle R?1¿ est tel que défini ci-dessus, pour obtenir des 5-hydroxypyrazoles de formule (I).
Patent EP-1121841-B1 (EP)
Inventor: KOERBER WERNER
IPC: H05K9/00
Filed: 1999-09-20
Granted: 2003-05-14
Abstract: The device contains at least one side part (1; 3) with a row of holes (13, 15; 17, 19), especially boreholes, or projections on a first edge (47, 48; 49, 50), and a cover part (21; 23) with a row of projections (33, 34; 35, 36), especially embossed knobs, or holes on a second edge (51, 52; 53, 54). The edges are aligned with each other in such a way that the holes and the projections engage in order to connect a side part and a cover part.
Patent EP-1138172-B1 (EP)
Inventor: RAAF BERNHARD
IPC: H04J13/00
Filed: 1999-12-01
Granted: 2007-04-18
Abstract: Pour l'observation de stations de base GSM, des phases d'interruption sont introduites dans une transmission SUTM. Pour que le nombre de ces phases d'interruption soient réduites, la station mobile est, pendant ces phases d'interruption, commutée sur la réception de paquets de données caractéristiques et de paquets de données à détecter qui sont envoyés par une station de base GSM.