baber/WOPTO huggingface dataset:
Patent CA-2372639-A1 (CA)
Title: Deuterated cyclosporine analogs and their use as immunomodulating agents
Inventor: NAICKER S SELVARAJ
IPC: A61K38/13
Filed: 1998-10-08
Abstract: Cyclosporine derivatives are disclosed which possess enhanced efficacy and reduced toxicity over naturally occurring and other presently-known cyclosporins and cyclosporine derivatives. The cyclosporine derivatives of the present invention are produced by chemical and isotopic substitution of the cyclosporine A (CsA) molecule by: (1) chemical substitution and optionally deuterium substitution of amino acid 1, and (2) deuterium substitution at key sites of metabolism of the cyclosporine A molecule such as amino acids 1, 4, 9. The most active derivatives of the invention were those possessing both chemical and deuterium substitution. Also disclosed are methods of producing the cyclosporine derivatives and method of producing immunosuppression with reduced toxicity with the disclosed cyclosporine derivatives.
Patent CA-2373156-A1 (CA)
Title: An offshore wind turbine with liquid-cooling
Inventor: FISCHER TORSTEN
IPC: F03D15/00
Filed: 2000-05-08
Abstract: An offshore wind turbine is disclosed wherein the power transmission in the nacelle is cooled by means of a liquid conducted to the nacelle from the tower on which the nacelle is pivotally arranged around a vertical yawing axis. The liquid transfers heat to the seawater near the turbine which is used as a heat sink of low temperature and enormous heat capacity as compared to traditional air cooling. The liquid is conducted in a closed circuit and the cooling system may comprise more than one cooling circuit. The flow of cooling-liquid may be conducted between the tower and the nacelle through a heat transfer unit having a first part that is stationary with respect to the tower and a second part that is stationary with respect to the nacelle. The parts have at least one annular passageway for a liquid flow defined between abutting surfaces of the parts.
Patent CA-2374851-A1 (CA)
Title: Tek antagonists
Inventor: FANSLOW WILLIAM C III
IPC: A61K31/475
Filed: 2000-06-07
Abstract: The present invention provides Tek antagonists and methods of inhibiting angiogenesis in a mammal by administering Tek antagonists. The methods are particularly useful in treating diseases or conditions mediated by angiogenesis, such as solid tumors and diseases or conditions characterized by ocular neovascularization.
Patent CA-2376317-A1 (CA)
Title: Network for remote administration of street lighting inter alia and methods to carry out said administration
Inventor: DENES ALAIN
IPC: H05B37/02
Filed: 2000-05-30
Abstract: A wireless data transmission network, comprising at least one lamp post with a transreceiver forming a node in said network. The transreceiver comprises a control circuit for a lamp. The invention also relates to a method for remote administration of lighting in a network, in addition to a lamp post fitted with a transreceiver and a connection box which can be mounted on a traditional lamp post, defining a node in said network.
Patent CA-2379118-A1 (CA)
Inventor: LITTLE ROGER G
IPC: C12Q1/26
Filed: 2000-04-06
Abstract: L'invention concerne de nouvelles méthodes de criblage qui permettent d'identifier des agents antimicrobiens et impliquent l'utilisation de colorants indicateurs d'oxydation-réduction métabolique.
Patent CA-2379360-A1 (CA)
Inventor: NYS GUY
IPC: C12P21/00
Filed: 2000-07-17
Abstract: The present invention relates to novel identified polynucleotides, polypeptides encoded by them and to the use of such polynucleotides and polypeptides, and to their production. More particularly, the polynucleotides and polypeptides of the present invention relate to the G-protein coupled receptor family, referred to as IGS1-family. The invention also relates to inhibiting or activating the action of such polynucleotides and polypeptides, to a vector containing said polynucleotides, a host cell containing such vector and transgenic animals where the IGS1-gene is either overexpressed, misexpressed, underexpressed or suppressed (knock-out animals). The invention further relates to a method for screening compounds capable to act as an agonist or an antagonist of said G-protein coupled receptor family IGS1 and the use of IGS1 polypeptides and polynucleotides and agonists or antagonists to the IGS1 receptor family in the treatment of psychiatric and CNS disorders.
Patent CA-2379603-A1 (CA)
Inventor: KOIVUKUNNAS PEKKA
IPC: G01N33/34
Filed: 2000-07-14
Abstract: An arrangement for measuring properties of a moving paper web. The arrangement comprises measuring means for measuring paper properties, in connection with which a plane-like support surface (4) is arranged. The plane-like support surface (4) supports the paper web (1) and extends substantially over the whole width of the paper web (1) in the cross-direction relative to the direction of travel (A) of the paper web (1). An opening arrangement formed by at least one opening (5) is arranged on the support surface (4) for measuring properties of the paper web (1).
Patent CA-2382688-A1 (CA)
Title: Melange d'allumage non toxique et non corrosif
Inventor: JIRASEK KAREL
IPC: C06C7/02
Filed: 2000-09-11
Abstract: L'invention concerne un mélange d'allumage non toxique et non corrosif, obtenu par combinaison du complexe énergétique et du complexe pyrotechnique. Le complexe énergétique comprend un explosif détonant des groupes des nitroesters et des nitramines, et un sensibilisateur du type tétrazène ou des dérivés des tétrazoles servant à son activation. Le complexe pyrotechnique comprend un comburant du groupe des oxydes et des peroxydes de métaux, du groupe des sels d'acides inorganiques oxygénés, et un combustible constitué d'un bore amorphe. Le mélange est additionné d'un agent de friction, de préférence du verre pulvérisé. De la nitrocellulose, du polyalcool de vinyle et de la gomme arabique sont utilisés comme agents de liaison. Ces mélanges s'utilisent pour fabriquer des munitions destinées à la production d'amorces, notamment pour des cartouches d'allumage central.
Patent CA-2387573-A1 (CA)
Inventor: JUX EGBERT
IPC: B65D75/36
Filed: 2000-11-17
Abstract: L'invention concerne un emballage-coque destiné à une lentille optique. Elle a pour objet d'améliorer cet emballage-coque de façon que ses parties de base (B) puissent être empilées et que le travail lié au triage puisse être sensiblement réduit. Ces améliorations peuvent être apportées grâce à l'utilisation d'éléments d'espacement (2, 3) et à l'assemblage de plusieurs parties de base (B) en une unité (17).
Patent CA-2388966-A1 (CA)
Title: Method and system for marketing and conducting a survey
Inventor: HODGINS MARC
IPC: G06Q30/02
Filed: 2002-06-05
Abstract: A method and system for marketing and/or conducting a survey includes the distribution of cards at a selected event to one or more individuals. The cards indicate contact information whereby the individuals are able to contact a host, such as a server connected to a network, conducting said marketing or conducting said survey. The cards also include a unique identifier associated with the event whereby the host is able to differentiate the individuals based on the event they have attended. The host also includes an information exchange system wherein the individuals first enter the unique identifier and, subsequently, further demographic data. The individuals are provided an incentive in the form of a contest or prize for contacting the host.
Patent CA-2389992-A1 (CA)
Title: Roller for a running-gear mechanism or for a roller battery
Inventor: MEINDL BERND
IPC: B60B37/00
Filed: 2002-06-10
Abstract: A roller for a running-gear mechanism or for a roller battery in a cableway system, having a roller body (1) which is designed with a central bore in which a bearing (2) is located, the roller being provided with two flanged disks (5) between which a more or less non-elastically deformable, annular support (4) for a cable of the cableway system is located, it being the case that at least one of the flanged disks (5) is fastened releasably on the roller body (1) in that the outer circumferential surface of the roller body (1) is designed, in the region of the abutting end surface of said roller body, with at least one encircling groove (12) for a spring ring (7) or the like. In this case, a resilient insert (6) is arranged between the support (4) and at least one of the flanged disks (5) (Fig. 1).
Patent CA-2391332-A1 (CA)
Inventor: MALCOLM BRUCE G
IPC: H01P7/10
Filed: 2000-11-10
Abstract: A cavity filter (8) includes a cavity (10) constituting an electrically conductive enclosure (12, 14, 16, 18, 20, 22), at least one resonator element (24-1,...24-n) constructed from a dielectric material, and a support (30) constructed from a relatively low loss dielectric support material for supporting the at least one resonator element (24-1,...24-n) in a desired orientation in the cavity (10). The support material has substantially higher thermal conductivity than the dielectric material.
Patent CA-2393904-A1 (CA)
Title: Hepoxilin analogs
Inventor: PACE-ASCIAK CECIL R
IPC: A61K31/557
Filed: 2000-08-03
Abstract: The present invention relates to the use of native hepoxilins and of hepoxilin analogs for the regulation of insulin secretion and to the use of hepoxilin analogs as anti-inflammatory, anti-diabetic and anti-thrombotic compounds.
Patent CA-2394260-A1 (CA)
Title: Rectified catadioptric stereo sensors
Inventor: NAYAR SHREE K
IPC: H04N13/239
Filed: 2000-12-13
Abstract: The invention presents catadioptric (single-camera) sensors using one or more mirrors (1-5) to produce rectified stereoscopic images. By combining multiple views (using the mirrors) to form a composite stereo image that is already rectified (i.e., has scan-line correspondence), the invention aids provision of real-time stereo images by avoiding computational cost and image degradation due to computer-rectification-related resampling when rectifying.  The invention specifies the number of mirrors (1-5) that must be used and the geometric/locational constraints on those mirrors that must be substantially satisfied to obtain rectified stereo images with a single camera. The invention also discloses specific configurational techniques for how the mirrors should be placed to minimize sensor size. The configurational/geometric parameters disclosed enable cost-efficient, compact, and error-tolerant single-camera stereoscopic image sensing system and methods, removing the need for computer-controlled image rectifying steps and allowing for convenient computerized capture, processing, manipulation, storage, and transmission of stereo images.
Patent CA-2394968-A1 (CA)
Title: Dosage forms having a barrier layer to laser ablation
Inventor: GEERKE JOHAN H
IPC: A61J1/03
Filed: 2000-12-11
Abstract: A dosage form for delivery of a therapeutic agent to a subject is described.  The dosage form contains: (a) an outer wall defining an interior compartment;  (b) within the interior compartment, a therapeutic agent; (c) at least one exit orifice formed by laser ablation of the outer wall for release of the agent therethrough, and (d) a barrier layer disposed between the outer wall and the interior compartment in at least a region corresponding to the exit orifice. The barrier layer comprises a material that allows the barrier layer to remain intact during laser-formation of the at least one exit orifice in the outer wall. Also disclosed is a method for controlling the depth of laser ablation of a dosage form during laser formation of an exit orifice in an outer wall of the dosage form.
Patent CA-2395332-A1 (CA)
Title: Embolic protection devices
Inventor: WHITFIELD JOHN D
IPC: A61M25/01
Filed: 2000-12-27
Abstract: An embolic protection device for use in a blood vessel when an interventional procedure is being performed in a stenosed or occluded region to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filtering assembly having a self-expanding strut assembly and a filter element attached thereto. In one embodiment, the filtering assembly is attached to the distal end of a guidewire and is deployed within the patient's vasculature as the guidewire is manipulated into the area of treatment. A restraining sheath placed over the filtering assembly in a coaxial arrangement maintains the filtering assembly in its collapsed position until it is ready to be deployed by the physician.  Thereafter, the sheath can be retracted to expose the filtering assembly which will then self-expand within the patient's vasculature. Interventional devices can be delivered over the guidewire and any embolic debris created during the interventional procedure and released into the blood stream will enter the filtering assembly and be captured therein. Other embodiments include filtering assemblies attached to an outer tubular member and inner shaft member which apply axial force to the distal ends of the assembly to either expand or contract the struts as needed.
Patent CA-2395972-A1 (CA)
Inventor: AKIN HAKAN
IPC: H04N21/278
Filed: 2000-03-27
Abstract: La présente invention concerne un procédé et une méthode permettant d'afficher des données dans une fenêtre de diffusion. Dans un mode de réalisation de l'invention, on actionne (1005) un pointeur en direction d'informations de contenu. Ces informations de contenu sont localisées (1010) à partir de données associées et elles sont affichées dans la fenêtre de diffusion (1015). Dans un autre mode de réalisation de l'invention, ces informations de contenu sont animées (1020) dans la fenêtre de diffusion.
Patent CA-2400106-A1 (CA)
Title: Anticorps anti-cd154 humain
Inventor: SCHULER WALTER
IPC: A61P25/28
Filed: 2001-03-14
Abstract: L'invention concerne une molécule de liaison CD154, notamment un anticorps anti- CD154 humain, plus spécifiquement un anticorps humain anti-CD154 humain, les CDR de la chaîne lourde et de la chaîne légère présentant des séquences d'acides aminés comme défini, pour le traitement et/ou la prévention de maladies ou de troubles. La modulation CD154 et/ou l'interférence avec les interactions CD154:CD40 ou l'inhibition desdites interactions sont bénéfiques sur le plan thérapeutique.
Patent CA-2405258-A1 (CA)
Title: Melanges polymeres ethylene/.alpha.-olefine comprenant des composants presentant des contenus en ethylene differents
Inventor: DANIEL CHRISTIAN
IPC: C08L23/16
Filed: 2001-05-11
Abstract: L'invention concerne un mélange polymère éthylène/ alpha -oléfine contenant des premier et des second composants polymères éthylène/ alpha -oléfine, le contenu en éthylène du premier composant contenant une différence d'au moins 10 % en poids par rapport au contenu en éthylène du second composant. Ces mélanges présentent une combinaison améliorée de basse température, d'écoulement de pastilles, de rémanence à la compression, de résistance à la fusion, et/ou de propriétés de mémoire de forme, comparés à l'un des composant ou à un mélange polymère éthylène/ alpha -oléfine de composition similaire, mais dans laquelle le contenu en éthylène de chaque composant est sensiblement le même.
Patent CA-2406605-A1 (CA)
Title: Method for making aquatic pools and in particular for swimming pools
Inventor: VICARIO ANTOINE
IPC: E04H4/00
Filed: 2001-06-21
Abstract: The invention concerns a method for making aquatic pools such as swimming pools, which consist in covering the panels (1) of a cavity with concrete. The invention is characterised in that it comprises the following steps: preparing a mixture of cement (2), sand (4) and fibres (3); transferring said mixture to a spray nozzle; simultaneously spraying said mixture and water on the wall to be covered, with the spray nozzle (12). The invention also concerns a pool, in particular for swimming obtainable by using said method. The invention is applicable to aquatic pools.
Patent CA-2406748-A1 (CA)
Title: Self-anchoring cementing wiper plug
Inventor: WEBER JAMES L
IPC: E21B33/16
Filed: 2002-10-03
Abstract: A self-retaining cementing wiper plug has two or more steel or carbide tipped holddown fingers or slips extending radially outward from the plug for engaging the inner surface of the casing and preventing the plug from moving uphole over time and potentially interfering with other downhole apparatus such as a pump.
Patent CA-2408806-A1 (CA)
Inventor: KAWAKAMI KATSUHIRO
IPC: A61K31/4709
Filed: 2001-03-30
Abstract: L'invention concerne un monohydrate de monochlorhydrate d'acide (-)-7-[7(S)-7-Amino-5-azapiro[2,4]heptane-5-yl]-6-fluoro-1-[(1R,2S)-2-fluoro-1-cyclopropyl]-1,4-dihydro-8-méthoxy-4-oxo-3-quinoléine-carboxylique et des agents antibactériens le contenant. Ce composé présente une activité antibactérienne et une innocuité élevées, ainsi qu'une haute stabilité à la lumière et à l'humidité, d'où son utilité comme agent antibactérien.
Patent CA-2410600-A1 (CA)
Inventor: LIDDLE HEATHER ANNE
IPC: C09D7/61
Filed: 2001-06-14
Abstract: Materials for coating, coating compositions, methods and articles of manufacture comprising a nanoparticle system or employing the same to impart surface modifying benefits for all types of inanimate hard surfaces are disclosed. In some embodiments, dispersement of nanoparticles in a suitable carrier medium allows for the creation of coating compositions, methods and articles of manufacture that create multi-use benefits to modified hard surfaces. These surface modifications can produce long lasting or semi-permanent multi-use benefits that include at least one of the following improved surface properties: wetting and sheeting, quick drying, uniform drying, soil removal, self-cleaning, anti-spotting, anti-soil deposition, cleaner appearance, enhanced gloss, enhanced color, minor surface defect repair, smoothness, anti-hazing, modification of surface friction, release of actives and transparency, relative to hard surfaces unmodified with such nanoparticle systems. In some embodiments, actively curing the coating composition on the hard surfaces, including, but not limited to by radiative heating the air surrounding the hard surface with the coating thereon can be used to increase the durability of the hard surface coating.
Patent CA-2411839-A1 (CA)
Title: High voltage distribution box with pre-molded lead frame
Inventor: MCLACHLAN RAYMOND B
IPC: H02B1/18
Filed: 2002-11-14
Abstract: A vehicle high voltage electrical distribution box including a housing and a lead frame assembly. The lead frame assembly is located in the housing. The lead frame assembly includes bus bars and an over molded frame which has been over molded onto the bus bars to connect the bus bars to each other.
Patent CA-2412217-A1 (CA)
Title: Hiv-1 reporter viruses and their use in assaying anti-viral compounds
Inventor: BLAIR WADE
IPC: C12N7/01
Filed: 2001-06-07
Abstract: The present invention relates to HIV-1 proviral constructs, which produce replication competent HIV-1 reporter viruses. The invention also relates to the use of these HIV-1 reporter viruses in high throughput screening of anti-viral compounds.
Patent CA-2415638-A1 (CA)
Title: A catalyst support, a supported group viii metal catalyst and a precursor thereof, processes for their preparation, and a use of the supported group viii metal catalyst
Inventor: VAN VLAANDEREN JOHANNES JACOBU
IPC: B01J23/889
Filed: 2001-07-10
Abstract: A process for preparing a catalyst support or a supported Group VIII metal catalyst or a precursor of the supported Group VIII metal catalyst, which process comprises (a) exerting mechanical power on a mixture comprising a refractory oxide and a first liquid to obtain a dough, (b) admixing the doug h with a second liquid to obtain a slurry, (c) shaping and drying the slurry, and (d) calcining.
Patent CA-2416563-A1 (CA)
Title: Pharmaceutical composition having specific water activity
Inventor: HENDL ONDREJ
IPC: A61K47/44
Filed: 2001-09-07
Abstract: A composition comprising (a) one or more bioactive agents; and (b) a non-aqueous liquid carrier; wherein immediately after manufacture of the composition, said composition can be administered to a host such that the one ore more bioactive agents is released to the host and wherein said composition has been adjusted to have a water activity of between about 0.2 and about 0.5 is provided.
Patent CA-2417332-A1 (CA)
Title: Stackable container with stack-tabs
Inventor: KENT DAVID
IPC: B65D21/02
Filed: 2003-01-23
Abstract: A tray-type container 10 includes a bottom wall 20, longitudinally-extending outer side walls 22, and laterally-extending end walls 24, the outer side walls 22 and the end walls 24 extending upwardly from the bottom wall 20 to form an inner cavity 26. As erected, the outer side walls 22 include a plurality of spaced-apart stacking tabs 28A-28D, and the bottom wall forms a plurality of spaced-apart apertures 60, 70, 80, 82, 86, and 88 for receiving the stacking tabs 28A-28D of like or similar containers. A  plurality of tray-type containers 10 may be unitized in several stacked configurations utilizing the stacking tabs 28 and apertures 60, 70, 80, 82, 86, and 88. Typically, the plurality of unitized containers 10 are placed upon a shipping pallet or slip sheet, or placed within a shipping container to facilitate shipping by large carriers.
Patent CA-2418940-A1 (CA)
Inventor: DAVIDOR YUVAL
IPC: H04W16/18
Filed: 2001-08-09
Abstract: A system and method for frequency planning in a wireless communication network area using an impact matrix (50) which relates signal interference impacts between sectors (54, 58) in a network service area for co-channel and adjacent channel interference. The impact matrix (50) uses weighted propagation analysis (60) and empirical measurement data (62) to determine signal levels within each pixel of a network service area. The system merges the propagation analysis (60) and empirical measurement data (62) according to user assigned confidences.
Patent CA-2419613-A1 (CA)
Inventor: COX DAVID
IPC: C12Q1/68
Filed: 2001-08-24
Abstract: La présente invention concerne plusieurs méthodes permettant de réduire la complexité d'une population d'acides nucléiques avant le démarrage de l'analyse des acides nucléiques sur une matrice de sondes d'acides nucléiques. Ces méthodes permettent d'obtenir un sous-ensemble de la population de départ enrichi de manière à présenter une propriété souhaitée ou ne contenant pas d'acides nucléiques présentant une propriété non souhaitée. Les acides nucléiques ainsi obtenus dans le sous-ensemble sont ensuite appliqués sur la matrice pour différents types d'analyses. Ces méthodes sont particulièrement utiles pour analyser des populations présentant un degré élevé de complexité, par exemple, un ADN chromosomal, un ADN génomique entier, ou une population d'ARNm. En outre, ces méthodes permettent d'analyser des échantillons regroupés.
Patent CA-2421357-A1 (CA)
Title: Humidifier for forced air furnaces
Inventor: FIELDS BRADLY R
IPC: F23D14/68
Filed: 2003-03-07
Abstract: Disclosed is a flow-through humidifier comprising an evaporator pad, a drip nozzle having a housing with an inlet fitting and an outlet fitting and a flow restrictor therebetween for producing discrete water drops at the outlet fitting. A first water supply tube has an outlet and is connected with the inlet fitting of the drip nozzle and has an inlet end adapted for connection to a source of pressurized water. A second water supply tube has an inlet end connected with the outlet fitting of the drip nozzle and has an outlet end disposed in a gravity flow relation with the evaporator pad. Water is supplied in discrete water drops to the evaporator pad by gravity flow of the water drops from the outlet end of the second water supply tube.
Patent CA-2422935-A1 (CA)
Inventor: FISCHER WOLFGANG
IPC: C08F2/48
Filed: 2001-09-12
Abstract: L'invention concerne un procédé pour produire un revêtement sur un matériau poreux et/ou absorbant par polymérisation, induite par rayonnement, d'un agent de revêtement fluide.