baber/WOPTO huggingface dataset:
Patent CA-2467265-A1 (CA)
Title: Composition pharmaceutique pour accroitre l'activite immunitaire et extrait de poria
Inventor: TSENG JERMING
IPC: A61K31/56
Filed: 2004-05-13
Abstract: Composition pharmaceutique destinée à renforcer l'immunité du corps humain qui contient de puissants constituants de composés de lanostane. Une méthode est mise au point en vue d'obtenir un extrait à partir d'un métabolite, d'un sclérote ou d'un produit de fermentation de Poria cocos (Schw) Wolf. L'extrait contient 5 % à 60 % de composés de lanostane par poids d'extrait et est exempt de sécolanostane pouvant inhiber le développement de l'immunité.
Patent CA-2467854-A1 (CA)
Title: Sir2 products and activities
Inventor: SUAVE ANTHONY
IPC: C12N9/10
Filed: 2002-11-21
Abstract: A novel compound, 2'/3'-O-acetyl-ADP-ribose, is provided. The compound is a mixture of the 2' and 3' regioisomers of 0-acetyl-ADP ribose, and is formed nonenzymatically from 2'-O-acetyl-ADP-ribose, which is the newly discovered product of the reaction of Sir2 enzymes with acetylated peptides and NAD+.  Analogs of 2'/3'-O-acetyl-ADP-ribose are also provided. Additionally, methods of preparing 2'/3'-O-acetyl-ADP-ribose, methods of determining whether a test compound is an inhibitor of a Sir2 enzyme, methods of detecting Sir2 activity in a composition, methods of deacetylating an acetylated peptide, and methods of inhibiting the deacetylation of an acetylated peptide are provided.  Prodrugs of 2'/3'-O-acetyl-ADP-ribose are also provided.
Patent CA-2470615-A1 (CA)
Inventor: OGAWA SHIRO
IPC: A44B18/00
Filed: 2004-06-10
Abstract: To provide a member for engaging and connecting sheets which is well suited for inserting sheets into a recess on the surface of a molded resin article such as a cushioning molded article for seats a molded article covered with sheets by using the member for engaging and connecting sheets and a process for producing the molded article. A member for engaging and connecting sheets, comprising a fixing portion which fixes sheets, an engaging portion and a linking portion which links the fixing portion and the engaging portion wherein a number of engaging elements are installed on outer surface of the engaging portion sheets which is linked with the member; and a process for producing a molded article which comprises inserting sheets into a recess on the surface of a molded article, engaging the sheets with a fastener tape embedded at the bottom of the recess, covering the surface of the molded article with the sheets, and fixing the sheets thereto.
Patent CA-2470809-A1 (CA)
Title: 6-amino-morphinan derivatives, method of manufacturing them and their application
Inventor: SCHMIDHAMMER HELMUT
IPC: A61P21/00
Filed: 2002-12-16
Abstract: This invention relates to compounds of the formula (I).  (see formula I)
Patent CA-2471942-A1 (CA)
Inventor: LESMES SCOTT
IPC: G06Q40/00
Filed: 2002-12-19
Abstract: The present invention is directed to a system and method for quantifying residential emissions reductions. In particular, the system and method may comprise the steps of: measuring an energy savings resulting from an energy savings opportunity in a residential property (100), calculating an emissions reduction resulting from the energy savings (200), aggregating a plurality of emissions reductions into a tradable commodity (300), monitoring the residential energy savings opportunities (400), monitoring the quantification of the emissions reduction (500), and verifying the quantification of the emission reduction (600). The system may include means for conducting each of these steps.
Patent CA-2472207-A1 (CA)
Title: Apparatus and method for endoscopic colectomy
Inventor: BELSON AMIR
IPC: A61B17/32
Filed: 2002-12-20
Abstract: Apparatus and methods for endoscopic colectomy are described herein. A colectomy device (102) having a first and a second tissue approximation devi ce is mounted on a colonoscope (100) separated from one another. During deployment of the colectomy device (102), a diseased portion of the colon is positioned inbetween the tissue approximation devices. The tissue approximation devices (104, 106) are radially expanded such that they contac t and grasp the colon wall at two sites adjacent to the diseased portion of th e colon. The diseased portion is separated from the omentum and is transected using a laparoscope or is drawn into the colonoscope (100) for later removal . The tissue approximation devices (104, 106) are then urged towards one anoth er over the colonoscope (100) to approximate the two free edges of the colon in to contact together where they are fastened to one another using the tissue approximation device as a surgical stapler to create an end-to-end anastomos is.
Patent CA-2475109-A1 (CA)
Title: Ice and snow engaging survival hooks
Inventor: LEMIRE YVON
IPC: A62B3/00
Filed: 2004-08-06
Abstract: A survival hook consisting of a pair of hooks rotationally attached to a plate which is itself provided with fastening means to retain the plate over clothing, typically over the forearm of a user. The plate can be of a strap-on type by way of fastening means or can be sown as part of the clothing or alternatively, it can be fixedly attached to the clothing by mechanical fastening means, adhesive means or combination thereof.  The hands are always free and unencumbered and the moving elements are simple enough that it is unlikely that jamming through frost or packed snow or ice can occur and hinder proper operation of the invention. The pair of hooks are normally folded against the plate so as not show their pointy ends, and are folded out only when needed.
Patent CA-2476133-A1 (CA)
Inventor: ZHENG JUN
IPC: B26B29/00
Filed: 2004-08-02
Abstract: A letter opener (100). Letter opener (100) comprises a main body (102) having an open side, a covering piece (104) for closing up the open side of main body (102), a cutting blade (106), made of a ceramic material, rotatably installed inside main body (102), a spring member (108) installed inside main body (102) for maintaining blade (106) in position and for countering the rotation motion of blade (106) when blade (106) is in cutting mode. On the upper portion of main body (102), there is provided a lip piece (110) having a lower straight surface extending laterally. A through guide groove (112) is formed in between lip (110) and the upper surface of covering piece (104). Blade (106) extends upward across substantially groove (112) at a substantially right angle. When letter opener (100) is sliding along a marginal edge of a letter, cutting blade (106) operates to pierce through one layer of the letter and to cut a cutting line thereon, which is generally parallel to and offset by a slight spacing from the edge of the letter. Letter opener (100) is convenient and safe to use and is of durable construction.
Patent CA-2476292-A1 (CA)
Title: Helical peptidomimetics
Inventor: WOLFE MICHAEL S
IPC: C07K7/06
Filed: 2003-02-14
Abstract: Helical peptidomimetic compounds as inhibitors of beta-amyloid production ar e provided. These inhibitors preferably inhibit intramembrane proteases, notab ly aspartyl secretases involved in the enzymatic cleavage of amyloid precursor protein (APP) to yield amyloid-.szlig. peptide. Methods are provided for making a medicament containing the compounds and for administering the compounds to treat .szlig.-amyloid-associated diseases, notably Alzheimer's disease.
Patent CA-2476542-A1 (CA)
Inventor: MEDVINSKY ALEXANDER
IPC: H04L9/08
Filed: 2003-02-25
Abstract: L'invention concerne un système de détection de clones dans un réseau de communication. Le système de l'invention comprend un KDC (centre de distribution de clé), couplé à des clients et à des serveurs d'application sur le réseau de communication. Lorsqu'un client souhaite avoir accès à un serveur d'application, il contacte le KDC. Le KDC vérifie alors si le client est autorisé à avoir accès au serveur d'application. Dans un mode de réalisation, cette vérification est effectuée par l'exécution d'un échange de clé Diffie-Hellman authentifié. Lorsque le client a été identifié par le KDC, celui-ci génère un ticket contenant une clé de session. Dans un mode de réalisation, ce ticket est valide pendant une durée déterminée. Dans un autre mode de réalisation, le KDC enregistre simplement le moment où le ticket a été généré. Aprés la génération du ticket, la clé de session est utilisée par le client pour authentifier sa demande d'accès et avoir accès au serveur d'application. Un clone souhaitant avoir accès au serveur d'application doit contacter le KDC pour obtenir sa propre clé authentifiée, et obtenir un ticket avec une nouvelle clé de session aléatoire. Le clone ayant dupliqué l'identité du client contacte alors le KDC pour demander accès au serveur d'application. Le KDC vérifie alors si la demande d'accès est préalable à l'expiration du ticket préalablement généré pour le client autorisé. Si tel est le cas, la demande d'accès est étiquetée comme une possible demande frauduleuse. De cette manière, la présente invention permet l'accès aux clients autorisés tout en empêchant l'accès aux client non autorisés. La détection du clonage peut se produire au niveau du KDC, ou elle peut se produire au niveau du serveur d'application auquel le client cherche à accéder.
Patent CA-2477195-A1 (CA)
Inventor: COLE STEWART
IPC: A61P31/06
Filed: 2003-02-25
Abstract: La présente invention concerne l'identification d'une séquence nucléotidique qui rend possible en particulier la distinction entre une infection résultant d'une large majorité de souches de <i>Mycobacterium tuberculosis</i> d'une infection résultant de <i>Mycobacterium africanum, Mycobacterium canetti, Mycobacterium microti, Mycobacterium bovis, Mycobacterium bovis BCG</i>. L'invention a également pour objet un procédé de détection des séquences mentionnées grâce aux produits d'expression de ces séquences et des kits pour mettre en oeuvre ces procédés. Pour finir, l'invention concerne de nouveaux vaccins.
Patent CA-2477940-A1 (CA)
Inventor: LIN HUAN
IPC: C12N15/10
Filed: 2003-03-03
Abstract: The present invention relates to materials and methods for the quantitative and qualitative analysis of gene expression during targeted differentiation of isolated homozygous stem cells, and to materials and methods for accumulatin g sequence tags sampled from a population of expressed genes. More particularl y, the present invention relates to a method for constructing a model of cellul ar development and differentiation comprising the steps of: (1) producing a homogenous population of homozygous stem (HS) cells; (2) directing the differentiation of the HS cells to arrive at desired mature (somatic) cells, group of cells or tissue; (3) periodically sampling HS cells undergoing differentiation to extract total cellular RNA produced at various sampling stages; (4) isolating mRNA from the total cellular RNA; and (5) constructing a cDNA library representative of proteins produced and expressed at various stages of differentiation, over the course of time. The present invention further relates to sequencing and cataloguing isolated mRNAs and cDNAs at various stages of differentiation of HS cells, producing and cataloguing isolated polypeptides sequences encoded by same, and screening the cDNA libraries. I vitro and in vivo cultures of homozygous stem cell are also described; such cultures find utility both as models of differentiation as well as sources of differentiated tissues and organs.
Patent CA-2478550-A1 (CA)
Title: Pull-on disposable diaper
Inventor: OTSUBO TOSHIFUMI
IPC: A61F13/15
Filed: 2003-02-19
Abstract: A pull-on disposable diaper is composed of a front waist region , a rear waist region , a crotch region extending between these waist regions and a body fluid absorbing component formed on inner side of these regions . The absorbing component is formed in the crotch region with a V-shaped first folding guide, a V-shaped second folding guide and a third folding guide extending in a transverse direction between the first and second folding guides. The absorbing component is folded along the third folding guide so that a core forming a part of the component may have its outer surface sections facing to each other and along the first and second folding guides so that the core may have its inner surface sections facing to each other.
Patent CA-2479215-A1 (CA)
Title: Device for generating aqueous chlorine dioxide solutions
Inventor: KOERMER GERALD S
IPC: A01N25/02
Filed: 2003-03-14
Abstract: The invention pertains to a device for generating aqueous chlorine dioxide solutions when the device is contacted with liquid water. The device comprises an alkali metal or alkaline earth metal chlorite, e.g., sodium chlorite, and a chemical reagent comprising an acid or a material capable of releasing an acid upon exposure to liquid water, e.g., sodium bisulfate. The chlorite and the reagent are either combined as a mixture or are disposed as separate components adhered to the surface of one or more substrates. Upon exposure to liquid water, the chlorite and the reagent produce boundary layers. The chlorite and the reagent are disposed upon, and adhered to, the surface(s) of the substrates in a manner such that upon exposure to liquid water, the chlorite boundary layer comes into contact with the reagent boundary layer to thereby produce an aqueous chlorine dioxide solution.
Patent CA-2479696-A1 (CA)
Title: Use of calphostin-c to treat drug-sensitive tumor cells
Inventor: PARISSENTI AMADEO
IPC: A61K31/704
Filed: 2004-08-31
Abstract: Calphostin C is used to treat subjects for cancer which is resistant to treatment by other forms of chemotherapeutic drugs, for example breast or uterine cancer, or other cancers characterized by tumor cells that have a defect in an apoptotic regulatory pathway which renders said cells resistant to at least some other forms of chemotherapeutic treatment. The other chemotherapeutic drug used with calphostin C is selected from the group comprising taxanes and anthracyclines, such as paclitaxel or doxorubicin. The use may take the form of administering calphostin C and then subjecting the patient to photodynamic therapy (PDT).
Patent CA-2480689-A1 (CA)
Title: Arrangement and methods for the manufacture of composite layer structures
Inventor: FINCKH HERMANN
IPC: B32B37/24
Filed: 2003-03-29
Abstract: Disclosed are devices and methods for producing cored composite materials (sandwich structures) comprising at least one first and at least one second coating (1, 2), between which a core layer (central layer) (30) containing short-cut fibers (9) is arranged. Said devices and methods make it possible to produce in an essentially uninterrupted manner, resulting in relatively inexpensive composite materials. In addition, individual production paramete rs can be specifically modified by means of different embodiments such that composite materials which have the desired physical properties, e.g. regardi ng the firmness, stiffness, flexibility, mechanical and acoustic absorbing capacity, processability, etc. thereof as well as composite materials used f or new applications can be produced in a relatively simple manner.
Patent CA-2481275-A1 (CA)
Inventor: BROWNING JAMES
IPC: A61F2/00
Filed: 2003-04-11
Abstract: La présente invention concerne un implant chirurgical (2) et une méthode de soutènement de l'urètre. L'implant comprend au moins une zone (6) de fixation pouvant être fixée dans le tissu fibro-graisseux de l'espace prévésical. Pendant l'utilisation, l'implant soutient l'urètre si bien qu'une pression intra-abdominale accrue est transmise à la région de pression sous-urétrale afin de permettre l'occlusion de l'urètre aux moments où s'exerce une pression intra-abdominale accrue. L'implant de l'invention peut être utilisé pour traiter l'incontinence d'urine et le prolapsus utérovaginal.
Patent CA-2482229-A1 (CA)
Title: Brewing apparatus water temperature control
Inventor: SCARCHILLI JOHN JOSEPH
IPC: A47J31/56
Filed: 2004-09-20
Abstract: A brewing apparatus, such as a coffeemaker, including a hot water heater; a first temperature sensor connected to the hot water heater; a second temperature sensor connected to either a cold water inlet to the heater or a hot water outlet from the heater; a pump connected to the cold water inlet for supplying water to the heater; and a controller coupled to the pump and the sensors. The pump is a variable speed pump. The controller is adapted to adjust the speed of the pump based upon signals from the sensors.
Patent CA-2482613-A1 (CA)
Title: Melanges de fluoropolymeres et articles multicouches
Inventor: MOLNAR ATTILA
IPC: C08L27/18
Filed: 2003-03-13
Abstract: L'invention concerne diverses combinaisons de mélanges de fluoropolymères et des articles à multiples couches qui comprennent un mélange dans une première couche et une deuxième couche comprenant un polymère lié à la première couche. L'invention traite également d'un article comprenant une première couche qui comprend un mélange de deux ou plusieurs fluoropolymères, et une deuxième couche liée à la première couche, la deuxième couche comprenant un polymère thermoplastique partiellement fluoré, un polymère thermoplastique perfluoré ou une combinaison de ces derniers. L'invention traite d'un article comprenant une première couche comprenant un mélange de deux ou plusieurs fluoropolymères, dont au moins un comprend un polymère thermoplastique partiellement fluoré, et éventuellement au moins un polymère perhalogéné, et une deuxième couche liée à la première couche, la deuxième couche comprenant au moins un polymère thermoplastique partiellement fluoré. L'invention traite également de procédés de préparation de fluoropolymères mélangés et d'articles multicouches comprenant une couche fluoropolymère.
Patent CA-2482955-A1 (CA)
Title: Splined clutch hub and method and apparatus for making same
Inventor: VASA BEN R
IPC: B21K1/30
Filed: 2003-06-03
Abstract: An externally splined clutch hub and method for making the same is disclosed wherein a flat circular metal perform (10) is contacted with a single forgin g die to simultaneously cold forge a centrally disposed tubular neck (14) extending outwardly from one side of the perform and simultaneously a spline d annular ring (16) at the periphery of the perform and extending outwardly fr om the other side of the perform wherein the tubular neck and the annular ring are coaxial.
Patent CA-2483280-A1 (CA)
Title: Excitation vector generator, speech coder and speech decoder
Inventor: EHARA HIROYUKI
IPC: G10L19/12
Filed: 1997-11-06
Abstract: A random code vector reading section and a random codebook of a conventional CELP type speech coder/decoder are respectively replaced with an oscillator for outputting different vector streams in accordance with values of input seeds, and a seed storage section for storing a plurality of seeds . This makes it unnecessary to store fixed vectors as they are in a fixed codebook (ROM), thereby considerably reducing the memory capacity.
Patent CA-2485642-A1 (CA)
Title: Process for the preparation of a n,n-diamino amino acid-.beta.-hydroxy disuccinic acid
Inventor: BERGLUND KRIS A
IPC: C07C229/00
Filed: 2003-05-15
Abstract: A process of the preparation of a N,N-diamino amino acid-.szlig.-hydroxy-succinic acid as a N,N-diacid salt (I) is described. The process involves reacting epoxy succinic acid with an amino acid having two amino groups as an N-acid salt. The compounds are useful as chelators.
Patent CA-2487346-A1 (CA)
Title: Cannabinoid receptor agonists
Inventor: KOZLOWSKI JOSEPH A
IPC: A61P1/16
Filed: 2003-06-17
Abstract: A compound of the formula (I) or a pharmaceutically acceptable salt thereof, wherein: R1, R2, R3, R4, R5, R6, L1, L2, M, n, p, X, Y and Z are as described in the specification; pharmaceutical compositions thereof, methods of making said pharmaceutical compositions; and methods of use thereof.
Patent CA-2487554-A1 (CA)
Inventor: KIM JI-YOUNG
IPC: C07B61/00
Filed: 2003-06-20
Abstract: Cette invention se rapporte à un procédé et à de nouveaux intermédiaires pour produire des inhibiteurs de transcriptase inverse d'HIV. Formules (I, II, III, IV, V, VI).
Patent CA-2487833-A1 (CA)
Inventor: SMITH NEWTON JAMES
IPC: G06Q10/10
Filed: 2003-06-13
Abstract: L'invention concerne un procédé, un système et un programme destinés aux communications consultables par contexte. Diverses parties du contenu d'une communication sont analysées pour identifier une réponse de réaction associée à chaque partie variante du contenu. Un attribut affichable est associé à chaque partie variante du contenu pour indiquer la réponse de réaction identifiée. Chaque partie variante du contenu est stockée pour la communication avec la réponse de réaction identifiée et l'attribut affichable associé dans une base de données consultable par un contexte contenant au moins les réponses de réaction identifiées ou les attributs affichables associés.
Patent CA-2491669-A1 (CA)
Title: Neoplasm specific antibodies and uses thereof
Inventor: MUELLER-HERMELINK HANS-KONRAD
IPC: C12N15/13
Filed: 2003-07-02
Abstract: The present invention features polypeptides, such as antibodies, and their use in the treatment and diagnosis of neoplasms.
Patent CA-2492545-A1 (CA)
Inventor: EISL JOCHEN
IPC: H04L45/50
Filed: 2002-07-15
Abstract: For optimized IP- routing the invention discloses a home agent and method for transfer of an IP packet over a path from a sender (CN) over a radio access network (RAN, HA, FA 11) to a mobile host (MS2), wherein, when a home agent (HA) receives an incoming data packet determined for a mobile host (MS2) with a destination address (MS2-address 137.21.16.5), the home agent (HA) examines if there is a match between the destination address (MS2-address: 137.21.16.5) of the packet and a subnetwork address (FA 11-address: 137.21.16.0) of a foreign agent (FA 11) stored in a list of subnetwork addresses (137.21.16.0;  137.22.25.0) stored in a list at the home agent (HA), wherein, if there is a match between the destination address (MS2-address: 137.21.16.5) and a subnetwork address (FA 11-address: 137.21.16.0) of a foreign agent, the home agent examines whether a preconfigured path from the home agent (HA) to this foreign agent exists and wherein the home agent (HA) sends the packet to this foreign agent (FA 11) on this preconfigured label switched path (37) if a label switched path (37) to this foreign agent exists.
Patent CA-2494269-A1 (CA)
Inventor: NELSON JADE DOUGLAS
IPC: C07D405/06
Filed: 2003-07-25
Abstract: L'invention concerne un procédé de préparation de phénylamide (I) d'acide carboxylique 5-(4-fluorophényl)-I-[2-((2R,4R)-4-hydroxy-6-oxo-tétrahydro-pyran-2-yl)-éthyl]-2-isopropyl-4-phényl-1<I>H</I>-pyrrole-3, un intermédiaire clé dans la synthèse du calcium d'atorvastatine.
Patent CA-2494473-A1 (CA)
Inventor: MODI PANKAJ
IPC: A61K8/68
Filed: 2005-02-14
Abstract: A stabilizing composition that also enhances permeation is provided for the topical or transdermal administration of an active ingredient. The composition comprises collagen, elastin, sphingoside and cerebroside. Also provided are pharmaceutical or cosmetic formulations comprising an effective amount of an active agent and the stabilizing composition as well as methods of administering active agents topically or transdermally.
Patent CA-2498168-A1 (CA)
Inventor: KILIBARDA VELIBOR
IPC: B62D65/02
Filed: 2005-02-24
Abstract: A workstation and method for processing a plurality of workpieces includes at least one material handling robot movable along a processing path for supporting a workpiece to be moved along the processing path. At least one station can be defined by at least one processing position adjacent the processing path for receiving workpieces to be processed when delivered and positioned by the at least one material handling robot. Interchangeable end effecters can be connected to the material handling robot for holding and supporting different configurations of workpieces. The material handling robot can disengage from the end effecter at the processing position, to allow engagement with a processing tool for performing additional processing operations on the workpiece. A flexible body workstation for assembling workpieces can use multiple robots and/or multiple fixtures for processing different workpiece configurations in any sequential order along two processing paths.