baber/WOPTO huggingface dataset:
Patent NZ-601712-A (NZ)
Title: System and method for shock isolation in a launch system
Inventor: KALMS WILLIAM
IPC: F41F3/00
Filed: 2011-03-01
Abstract: A projectile launching system includes a shock isolator 220 of at least three planar resilient support members defining a circumferential wall extending vertically between the projectile mounting frame 214 and a base portion 206. The shock isolator defines an opening through the isolator that provides for the uninterrupted flow of expelled rocket gases, as well as underside access to the projectile mounting frame. Each planar resilient support member forms an integral spring arrangement within the support member.
Patent NZ-603560-A (NZ)
Title: Improved complement receptor 2 (cr2) targeting groups
Inventor: HANNAN JONATHAN P
IPC: C07K14/705
Filed: 2011-05-13
Abstract: Disclosed is a soluble composition capable of targeted delivery of a complement modulator to sites of complement system activation comprising a construct, wherein the construct comprises: (a) a complement receptor 2 (CR2) portion comprising at least the first two N-terminal short consensus repeat (SCR) domains of CR2; and (b) a complement modulator portion; wherein the CR2 portion contains at least one amino acid substitution selected from the group consisting of N11 and Y64 relative to SEQ ID NO: 2 that decreases binding affinity of the construct for EBV gp350 and/or at least one amino acid substitution selected from the group consisting of S42 and K50 relative to SEQ ID NO: 2 that decreases binding affinity of the construct for Interferon-alpha (IFNα), and wherein the construct exhibits comparable binding affinity for at least one complement component 3 (C3) proteolytic fragment as compared to a construct in which the CR2 portion does not contain the at least one amino acid substitution. Further disclosed is a method for making a construct that selectively binds to one or more C3 proteolytic fragments but does not selectively bind to EBV gp350 or IFNα, wherein the method comprises: (a) mutating one or more amino acids in a complement receptor 2 (CR2) portion of the construct at a position selected from the group consisting of: N11 and Y64 relative to SEQ ID NO: 2; and (b) mutating one or more amino acids in a complement receptor 2 (CR2) portion of the construct at a position selected from the group consisting of: S42 and K50 relative to SEQ ID NO: 2, wherein the construct comprises: (i) a complement receptor 2 (CR2) portion comprising at least the first two N-terminal SCR domains of the CR2 protein; and (ii) a complement modulator portion.
Patent NZ-604423-A (NZ)
Title: Prodrugs of nh-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives
Inventor: ALMARRSON ORN
IPC: A61K31/496
Filed: 2011-06-24
Abstract: Disclosed herein is a method of sustained delivery of a lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug by administering to a patient an effective amount of a prodrug compound of the invention wherein upon administration to the patient, release of the parent drug from the prodrug is sustained release. Prodrug compounds suitable for use in the methods are labile conjugates of parent drugs that are derivatized through carbonyl linked prodrug moieties, specifically compounds if formula VI or VII, wherein the variables are defined in the specification. The prodrug compounds can be used to treat any condition for which the lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug is useful as a treatment. In one embodiment the compound is 1-(butyryloxy)ethyl 7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-dihydroguinoline-1(2H)-carboxylate.
Patent NZ-616724-A (NZ)
Title: Methods and systems for securing chattels
Inventor: VOGT ERIC
IPC: G08B13/02
Filed: 2012-03-16
Abstract: Disclosed are system and method for determining the location of a container (105). The system comprises a SIM card associated with the container (105) and a modem associated with the container (105) and in communication with the SIM card. The SIM card stores information identifying the SIM card. The modem receives information corresponding to the location of the SIM card, retrieves the information identifying the SIM card. Then the modem transmits the location and identification information to a remote server (110) via short message service (SMS).
Patent NZ-622218-A (NZ)
Title: Media enabled shopping cart system and associated methods
Inventor: GIBBONS JAMES E JR
IPC: G06Q30/00
Filed: 2008-03-25
Abstract: Disclosed is a system for securing a position in a service queue from locations in a store remote from the service queue. The system includes an electronic queue number request signal generator (330) integrated with a media enabled shopping cart and operable by a customer from locations in the store remote from the service queue. The electronic queue number request signal generator (330) is configured to generate an electronic queue number request signal employed to obtain a queue number (360). A queuing number processor (313) is included and has an electronic queue number request signal receiver (364) for receiving the electronic queue number request signal. An electronic queue number generator (369) generates the queue numbers (360) in response to the electronic queue number request signals which are generated and assigned on a basis other than in response to sequential requests for queue numbers (360). An electronic queue number provider (361) communicates the queue number generated pursuant to the electronic queue number request signal to components of the system. A display component (75) displays information concerning the queue number (360) to the customer.
Patent NZ-627111-A (NZ)
Title: Variants of activin iib receptor polypeptides and uses thereof
Inventor: TAM LEI-TING TONY
IPC: C07K14/72
Filed: 2009-11-24
Abstract: Disclosed is a dimer comprising an isolated protein comprising a variant activin IIB receptor polypeptide (vActRIIB), wherein said polypeptide is selected from the group consisting of: (a) a polypeptide having the polypeptide sequence set forth in SEQ ID NO: 18, except for an amino acid substitution at position 28 with respect to SEQ ID NO: 18, wherein the substitution is a substitution of E with an amino acid selected from any one of A, F, Q, V, I, L, M, K, H, W and Y; (b) a polypeptide having the polypeptide sequence set forth in amino acids 19 through 134 of SEQ ID NO: 18, except for an amino acid substitution at position 28 with respect to SEQ ID NO: 18, wherein the substitution is a substitution of E with an amino acid selected from any one of A, F, Q, V, I, L, M, K, H, W and Y; (c) a polypeptide having the polypeptide sequence set forth in amino acids 23 through 134 of SEQ ID NO: 18, except for an amino acid substitution at position 28 with respect to SEQ ID NO: 18, wherein the substitution is a substitution of E with an amino acid selected from any one of A, F, Q, V, I, L, M, K, H, W and Y; (d) a polypeptide having the polypeptide sequence set forth in amino acids 25 through 134 of SEQ ID NO: 18, except for an amino acid substitution at position 28 with respect to SEQ ID NO: 18, wherein the substitution is a substitution of E with an amino acid selected from any one of A, F, Q, V, I, L, M, K, H, W and Y; and (e) a polypeptide having at least 90% identity to any one of (a) through (d), wherein the substitution at position 28 is a substitution of E with an amino acid selected from any one of A, F, Q, V, I, L, M, K, H, W and Y, and wherein the polypeptide is capable of binding myostatin, activin A, or GDF-11. Also disclosed is the use of the dimer in the manufacture of a medicament for inhibiting myostatin.
Patent NZ-628024-A (NZ)
Title: Methods and devices in the field of treatment with medical gases
Inventor: HEINE DANIEL
IPC: G01F1/68
Filed: 2011-11-15
Abstract: Disclosed is a method for monitoring gas flow in a tube. The method comprising inducing a temperature profile within a first portion, measuring a temperature in a second portion, evaluating the measured temperature and controlling a heating power. The temperature profile is predefined and designed to cause a change in temperature of the gas flowing through the first portion of the tube. The second portion is positioned downstream of the first portion and arranged to receive the gas flow from the first portion. The temperature measured being in response to the temperature profile induced in the first portion. The evaluation of the measured temperature being based on at least a characteristic associated with the predefined temperature profile. The evaluation is used to determine the level of gas flow through the tube. The heating power is controlled based on the level of gas flow through the tube, to prevent overheating of the tube.
Patent NZ-710701-A (NZ)
Title: A tile floor/wall covering system and related components
Inventor: SMITH BRADLEY WILLIAM
IPC: E04F21/165
Filed: 2012-10-24
Abstract: Disclosed is a tile system comprising a plurality of quadrilateral shaped tiles having two spaced apart face sides and 4 edges extending between said face sides, an elongate spacer to locate between at least two adjacent tiles to space said tiles from each other and to locate in a slot or rebate of each so spaced tile. The two spaced apart face sides are a back side and a front side. The rebate or slot is located intermediate of said face sides. The rebate or slot is a rebate and is located at the junction of a face side and The slot or rebate is located midway between the two face sides. Each said side of each said tile has a slot or rebate The slot or rebate of each side of said tile is coplanar each other. The slot or rebate extends parallel to the face sides of the tile. Both face sides are planar and parallel to each other. The spacer is of constant cross section and is elongate. The spacer is straight. The spacer can extend between two rows of a plurality of tiles. The spacer can help align a row of tiles. The spacer can help align two adjacent rows of tiles. Secondary spacers are provided that laterally extend between two parallel first mentioned spacers located each side of a row of tiles and space adjacent tiles in that row from each other. The secondary spacers are of the same cross section as the first mentioned spacer.
Patent NZ-712693-A (NZ)
Title: Compositions and methods for immunotherapy
Inventor: VICTOR D FEDOROV
IPC: A61K39/00
Filed: 2014-03-17
Abstract: The present invention provides immunoresponsive cells, including T cells, cytotoxic T cells, regulatory T cells, and Natural Killer (NK) cells, expressing an antigen recognizing receptor and an inhibitory chimeric antigen receptor (iCAR). Particularly, the antigen binding receptor binds to a first antigen on a tumour tissue, activating the immunoresponsive cell whereas the iCAR binds to a second antigen a normal and/or non-neoplastic tissue but is not expressed on said tumor tissue to inhibit the immunosuppressive cell. This achieves reduced off-target cytotoxic effects of the immunoresponsive cell during immunotherapy procedures. Methods of using the immunoresponsive cell include those for the treatment of neoplasia and other pathologies where an increase in an antigen-specific immune response is desired.
Patent NZ-713343-A (NZ)
Title: Targeted modification of rat genome
Inventor: YANCOPOULOS GEORGE D
IPC: C12N15/85
Filed: 2014-04-16
Abstract: Compositions and methods are provided for modifying a rat genomic locus of interest using a large targeting vector (LTVEC) comprising various endogenous or exogenous nucleic acid sequences as described herein. The method comprises: (a) culturing a population of pluripotent rat cells on a layer of feeder cells that is not modified to express leukemia inhibitory factor (LIF) with a medium comprising 50 U/mL to 150 U/mL LIF, N2 supplement, B27 supplement, and a combination of inhibitors consisting of PD0325901 and CHIR99021; (b) introducing into the pluripotent rat cells a LTVEC comprising an insert nucleic acid flanked by a 5’ homology arm complementary to a first nucleic acid sequence at the genomic locus of interest and a 3’ homology arm complementary to a second nucleic acid sequence at the genomic locus of interest, wherein the sum total of the 5’ and the 3’ homology arms is at least 10 kb, and wherein the LTVEC is from 20 kb to 400 kb; and (c) identifying a genetically modified pluripotent rat cell comprising a targeted genetic modification at the genomic locus of interest, wherein the targeted genetic modification is transmitted through the germline.
Patent NZ-718139-A (NZ)
Title: Powered mobility device with tilt mechanism having multiple pivots
Inventor: KEVIN THOMAS HALSALL
IPC: A61G5/10
Filed: 2015-04-10
Abstract: Disclosed is an easily operable powered wheelchair that is able to be controlled by the weight displacement of a user, especially a user with significant loss of movement of their limbs. The powered wheelchair 100 has a tilt mechanism having multiple pivots that allow the user to operate and control the backwards and forwards movement and steering of the wheelchair 100 in response to the displacement of the user’s weight within the wheelchair 100. The wheelchair 100 has two spaced apart drive wheels 101, each mounted to a separate shaft 104 that is independent of the other drive wheel. A drive controller drivingly coupled to the shafts 104 and the drive controller is housed within a base 102 that is pivotally situated on the shafts 104. A seat 103 mounted on a tilt mechanism enables the seat to tilt in a forward, backward, left and right direction as a result of the user displacing their body weight in either of those directions. The tilt mechanism includes three pivots, a primary pivot P1, secondary pivot P2 and tertiary pivot P3. The primary pivot P1 pivotally connects the base 102 to the shafts 104. The secondary pivot P2 is situated above and adjacent the base 102 so that the respective ends of the rod 105 are pivotally connected to the base 102. The tilt mechanism and the drive controller are connected to a weight displacement sensor to control the movement and direction of travel of the wheelchair 100. Both the primary and secondary pivots P1 & P2 allow the seat 103 to pivotally move in a forward and backward direction (103F, 103B) relative to the wheels 101 and such movement is sensed by the weight displacement sensor that in turn causes the drive controller to impart drive to one or both of the drive wheels to move the wheelchair 100 in the sensed direction e.g. forward or backward. The secondary pivot P2 enhances the offset of weight transfer by a user so as to cause increased control of the back or forward tilt (103F, 103B) of the seat 103 relative to the shaft 104 which is not possible with just a primary pivot P1. The tertiary pivot P3 is situated above the secondary pivot P2 and is situated below and adjacent the seat 103 so as to pivotally connect the respective ends of the rod 105 to the seat. Tertiary pivot P3 allows the tilt mechanism to tilt the seat 104 in left and right directions (103R, 103L) and the weight displacement sensor upon sensing left or right movement causes the drive controller to impart drive to one or both of the drive wheels to turn the wheelchair 100 left or right.
Patent NZ-721413-A (NZ)
Title: Processes for obtaining microbial oil from microbial cells
Inventor: LEININGER NEIL FRANCIS
IPC: A23D7/00
Filed: 2014-12-19
Abstract: Disclosed herein are processes for obtaining a microbial oil comprising one or more polyunsaturated fatty acids (PUFAs) from one or more microbial cells by lysing the cells to form a lysed cell composition and then recovering the oil from the lysed cell composition. Further disclosed herein is microbial oil comprising one or more PUFAs that is recovered from microbial cells by at least one process described herein. In particular, the present invention relates to a process for obtaining microbial oil comprising one or more polyunsaturated fatty acids (PUFAs), where the process comprises: (a) lysing the cells comprising the microbial oil to form a lysed cell composition comprising liquid, cell debris, and microbial oil; (b) demulsifying the lysed cell composition comprising adding at least one enzyme; (c) separating the oil from the demulsified lysed cell composition; (d) recovering the oil.
Patent NZ-724821-A (NZ)
Title: Assembly for energy absorption in an overload event
Inventor: BATTLOGG STEFAN
IPC: F16F9/53
Filed: 2015-03-13
Abstract: Assembly with an energy absorber for energy absorption in an overload event to reduce a resulting load on an object coupled with the assembly to avoid excessive load on the object by way of the energy absorption of the energy absorber in the overload event. The energy absorber comprises a fastener provided thereat and a holding device provided on the energy absorber which energy absorber is provided to absorb energy in a relative motion between the fastener and the holding device. The energy absorber comprises an absorber cylinder and a piston device with an absorber piston and a piston rod connected therewith. The absorber piston defines on the absorber cylinder a first chamber of an absorber chamber which is filled with a field-sensitive absorber fluid. The piston device is provided with an absorber valve with an absorber duct extending in an axial direction which absorber duct can be exposed to a field of the field generating device. A ratio of the outer diameter of the piston rod to an outer diameter of the absorber piston is larger than 0.6 and the first chamber filled with the field-sensitive absorber fluid extends in a space around the piston rod so that during the relative motion of the fastener and of the holding device of the energy absorber during the energy absorption in the overload event the field-sensitive absorber fluid is urged through the damping gap of the absorber piston.
Patent NZ-735461-A (NZ)
Title: Disease resistance loci in onion
Inventor: RICK JONES
IPC: A01H5/00
Filed: 2014-09-09
Abstract: Disclosed is a method of detecting in at least one onion plant a genotype associated with bulb colour, the method comprising the step of: (i) detecting in at least one onion plant an allele of at least one polymorphic nucleic acid that is associated with bulb colour, wherein the polymorphic nucleic acid is in or genetically linked to an onion genomic region defined by the loci NQ0257220 (SEQ ID NO: 26) and NQ0257692 (SEQ ID NO: 29) on linkage group 2 (LG2), conferring lack of complimentary pinks bulb colour. Further disclosed are methods of producing a plant or introgression methods with the phenotype as defined.
Patent NZ-735607-A (NZ)
Title: Cd20 binding molecules and uses thereof
Inventor: BALIGA RAMESH
IPC: C12P19/34
Filed: 2016-03-04
Abstract: This disclosure provides pentameric and hexameric CD20 binding molecules and methods of using such molecules to direct complement-mediated, T-cell-mediated, or both complement- mediated and T-cell-mediated killing of CD20-expressing cells.
Patent NZ-740608-A (NZ)
Title: Clinical formulations
Inventor: GAY ROGER
IPC: A61K9/08
Filed: 2016-08-18
Abstract: Some aspects of this disclosure provide clinical media that support viability, re- plating efficiency, and repopulation capacity of cells and tissues during storage for up to 48 hours or longer. The clinical media provided herein are also useful for clinical irrigation. Cell or tissue preparations comprising a cell population or tissue and a clinical medium as provided herein are also provided, as are methods for generating such preparations. The clinical preparation may comprise: a) about 0.1-1.2 mM CaCl2, about 0.05-5 mM MgCl2, about 1-2.5 mM KCl, about 0.5-2 mM sodium citrate, about 15-17 mM dextrose, and about 125-175 mM NaCl; b) about 0.5-0.9 mM CaCl2, about 0.2-0.4 mM MgCl2, about 1.6-2.4 mM KCl, about 0.8-1.2 mM sodium citrate, about 13-19 mM dextrose, and about 116-174 mM NaCl or c) about 0.008-0.012% CaCl2 dihydrate, about 0.0048-0.0072% MgCl2 hexahydrate, about 0.012-0.018% KCl, about 0.028-0.042% sodium citrate dihydrate, about 0.23-0.35% dextrose, and about 0.68-1.02 % NaCl. Methods for using the clinical media and cell and tissue preparations provided herein, for example, for administering an effective amount of cells or tissue to a subject in need thereof, are also disclosed.
Patent NZ-759254-A (NZ)
Title: Buffer device for press-fitting
Inventor: REN BINGWEN
IPC: B23P19/02
Filed: 2019-11-15
Abstract: The purpose of the present invention is to provide a buffer device for press-fitting, which can prevent a rotary plate from inclination under stress during a press-fitting process as much as possible. The buffer device comprises a rotary plate and a press both arranged on a working platform, wherein the press comprises a press head; a buffer seat is arranged on the rotary plate; a positioning seat for positioning a workpiece is arranged on the buffer seat; by the movement of the rotary plate, the buffer seat is moved to a position directly below the press head; the buffer seat comprises an upper moving block, a fixed block and a lower moving block; a fixation hole running through the rotary plate from upper and lower sides is formed on the rotary plate; the fixed block is fixed in the fixation hole; a number of accommodating grooves running through the fixed block from upper and lower sides are formed on the fixed block; guide rods are slidingly fitted in the accommodating grooves; compression springs are sheathed on the guide rods; upper ends of the guide rods are fixed to the upper moving block, while lower ends thereof are fixed to the lower moving block; and, upper ends of the compression springs come into contact with a lower end face of the upper moving block.
Patent PT-101908-A (PT)
Title: Anatomical mattress
IPC: A47C27/20
Filed: 1996-08-20
Abstract: Mattress consisting initially of an inner structure made from a series of plates similar to battens 1 in which each one of them has, on one of its faces, "male" parts 2 which will fit into the lower part of the structure which in turn consists of a solid plate 3 equipped with "female" parts 4 which constitute the fittings which correspond to the "male" parts 2 of the battens 1, above springs 5 or above any other suitable type of cushioning device. <IMAGE>
Patent PT-102093-A (PT)
Title: Universal platform kit for placement on the chassis of automobiles for parking and facilitating manoeuvres
IPC: B62D21/00
Filed: 1997-12-23
Abstract: The invention refers to a universal platform kit intended for placement on the chassis of automobiles and other industrial machines to facilitate the manoeuvring and the parking, characterised by round or square steel tubing 7 and 12 with bolts and nuts for adjustment 6, and it can enlarge or increase the dimensions according to the vehicle being used. The system is operated by motors 8, 9 and 10 with electric current coming from a battery. It should only operate when the clutch is down, the brake is down, and the hand brake is up; when the driver performs these operations, the electrical control circuit, which can be next to the steering wheel, enters into operation. <IMAGE>
Patent PT-103796-A (PT)
Title: Sistema de geração de energia baseado na acumulação de energia cinética.
Inventor: QUELHAS AUGUSTO NELSON MARTINI
IPC: F03G3/08
Filed: 2007-07-23
Abstract: SISTEMA DE GERAÇÃO DE ENERGIA BASEADO NA ACUMULAÇÃO DE ENERGIA CINÉTICA, NÃO PRODUZINDO EMISSÕES DE GASES NEM OUTROS IMPACTOS NEGATIVOS NO MEIO AMBIENTE. O CONCEITO BÁSICO É UMA MASSA ROTATIVA DESCENTRADA, APOIADA NUMA ESTRUTURA PENDULAR OSCILANTE, CUJO PONTO DE EQUILÍBRIO É A VERTICAL. EMMOVIMENTO, A MASSA ROTATIVA IMPULSIONA E É IMPULSIONADA PELA ESTRUTURA PENDULAR, ATRAVÉS DE UM MÓDULO DE IMPULSÃO SINCRONIZADO, QUE UTILIZA UMA PEQUENA FRACÇÃO DA ENERGIA GERADA PELO SISTEMA. PARA OPERAR O SISTEMA TEM QUE SER LANÇADO, MAS O INPUT DE ENERGIA INICIAL DILUI-SE NO OUTPUT GLOBALGERADO PELO POSTERIOR FUNCIONAMENTO CONTÍNUO.