baber/WOPTO huggingface dataset:
Patent PT-730587-E (PT)
Inventor: KLEINMAN EDWARD F
IPC: A61P43/00
Filed: 1994-10-12
Abstract: PCT No. PCT/IB94/00313 Sec. 371 Date May 15, 1996 Sec. 102(e) Date May 15, 1996 PCT Filed Oct. 12, 1994 PCT Pub. No. WO95/14680 PCT Pub. Date Jun. 1, 1995This invention relates to 3-aryl-2-isoxazoline compounds which are selective inhibitors of phosphodiesterase type IV (PDEIV). The 3-aryl-2-isoxazolines are useful in the treatment of AIDS, asthma, arthritis, bronchitis, chronic obstructive pulmonary disease, psoriasis, allergic rhinitis, dermatitis, shock, atopic dermatitis, rheumatoid arthritis and osteoarthritis. This invention also relates to pharmaceutical compositions useful therefor.
Patent PT-730861-E (PT)
Inventor: FORESTA PIERO
IPC: A61K31/138
Filed: 1996-02-26
Abstract: The use of 6,7-substituted-2-aminotetralines (e.g. 2-amino-6-fluoro-7-methoxytetraline) is disclosed for preparing pharmaceutical compositions useful for the treatment of septic shock and having antiinflammatory and antipyretic activities.
Patent PT-751117-E (PT)
Inventor: ROBEY ROGER LEWIS
IPC: C07C229/50
Filed: 1996-06-26
Abstract: A process for the preparation of (+)-2-amino-bicycloÄ3.1.0Ü-hexane-2-6-dicarboxylic acid, or a pharmaceutically acceptable salt thereof, which comprises hydrolysing (-)-2-spiro-5'-hydantoinbicycloÄ3.1.0Ühexane-6-carboxylic acid or a salt thereof, and optionally forming a pharmaceutically acceptable salt. Also disclosed are novel intermediates useful in the process.
Patent PT-779030-E (PT)
Inventor: WILHELM RUESS
IPC: A01N65/00
Filed: 1996-12-03
Abstract: Plant protectant compositions with synergistic activity against plant diseases contains: (A) a benzothiadiazole-7-carboxylic acid derivative of formula (I) having plant immunising action; (B) a compound selected from (B1) 4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-acryloyl)-morpholine (dimethomorph), (B2) 5-methyl-1,2,4-triazolo(3,4-b)(1,3)benzothiazole (tricyclazole) and (B3) 3-allyloxy-1,2-benzothiazole-1,1-dioxide (probenazole); and (C) a carrier. Z = CN, COOH (or salt), (1-4C) alkoxycarbonyl or (1-4C) alkylthiocarbonyl.
Patent PT-844938-E (PT)
Inventor: MACLIVER KEVIN SCOTT
IPC: B60N2/28
Filed: 1996-09-06
Abstract: PCT No. PCT/GB96/02210 Sec. 371 Date Mar. 6, 1998 Sec. 102(e) Date Mar. 6, 1998 PCT Filed Sep. 6, 1996 PCT Pub. No. WO97/09194 PCT Pub. Date Mar. 13, 1997The invention relates to a children's safety seat, particularly for the carrying of more than one child. It includes a children's safety seat to be securely and releasably attached to anchorage points in a motor vehicle when positioned on an existing seat of the vehicle. The seat can be provided with a back portion and a base portion which are sub-divided to provide a plurality of individual seats. The seat has integral members to enable it to be anchored in position.
Patent PT-853661-E (PT)
Inventor: THOMSON JULIA ELIZABETH
IPC: A61P13/12
Filed: 1996-10-07
Abstract: Specific binding members comprising human antibody antigen binding domains specific for human transforming growth factor beta (TGF beta ) bind specifically isoforms TGF beta 2 and TGF beta 1 or both, preferentially compared with TGF beta 3. Specific binding members may be isolated and utilised in the treatment of disease, particularly fibrotic disease and also immune/inflammatory diseases. Therapeutic utility is demonstrated using in vitro and in vivo models. Full sequence and binding information is provided, including epitope sequence information for a particularly advantageous specific binding member which binds the active form of TGF beta 2, neutralising its activity, but does not bind the latent form.
Patent PT-988391-E (PT)
Inventor: MEHTALI MAJID
IPC: C12N15/09
Filed: 1998-06-02
Abstract: The invention concerns a recombinant adenoviral vector driving from an adenovirus genome at least by deleting all or part of the E1 region, the adenoviral vector comprising an expression cassette of a gene of interest placed under the control of elements necessary for its expression in a host cell or a host organism, the elements required for its expression including at least a splicing sequence. The invention is characterized in that the splicing sequence is derived from a eukaryotic nuclear gene selected among the ovalbumen genes, beta or beta-globine, collagen and factor VIII of mammals or a synthetic splicing sequence. The invention also concerns a host cell and an infectious viral particle comprising such a vector, a method for preparing such a particle and their therapeutic or prophylactic use. The invention further concerns a pharmaceutical composition containing the adenoviral vector, the host cell or the viral particle.
Patent PT-1003865-E (PT)
Title: Mutation within the connexin 26 gene responsible for prelingual non-syndromic deafness and method of detection
Inventor: GUESDON JEAN-LUC
IPC: C12Q1/6886
Filed: 1998-08-14
Abstract: A purified polynucleotide having a chain of nucleotides corresponding to a mutated sequence, which in a wild form encodes a polypeptide implicated in hereditary sensory defect wherein said mutated purified polynucleotide presents a mutation responsible for prelingual non-syndromic deafness selected from the group consisting of a specific deletion of at least one nucleotide.
Patent PT-1022272-E (PT)
Inventor: FUJIWARA TOSHIHIKO
IPC: A61P9/00
Filed: 1998-10-08
Abstract: Described is a substituted fused heterocyclic compound which is represented by the following formula: <CHEM>  Äwherein R<1> represents a group of the following formula: <CHEM> (in which R<4>: a substituted phenyl or a pyridyl which may have a substituent, R<5>: a hydrogen atom or the like, R<6>: a hydrogen atom, a C1-6 alkyl group or the like, D: an oxygen or sulfur atom, E: a CH group or a nitrogen atom, R<2>: a hydrogen atom or the like, R<3>: a 2,4-dioxothiazolidin-5-ylmethyl group or the like; A: a C1-6 alkylene group, and B: an oxygen or sulfur atomÜ or a pharmacologically acceptable salt thereof; and has excellent insulin-resistance improving action, lipid-peroxide-production inhibitory action, 5-lipoxygenase inhibitory action and the like.
Patent PT-962429-E (PT)
Inventor: SCHMIDT UWE
IPC: C03C17/36
Filed: 1999-06-04
Abstract: Glazing has a metallic reflective multilayer comprising a dielectric base layer, a reflective chromium, chromium alloy or aluminum alloy layer and a dielectric external cover layer. Glazing is provided with a metallic reflective layer stack which withstands thermal treatment, especially annealing, bending and toughening, and which comprises (a) a dielectric base layer of SiO2 or of Al2O3, SiON, Si3N4 and/or AlN; (b) a highly reflective metallic layer of chromium or a chromium alloy, especially a CrAl alloy containing 20-25 wt.% Al, a CrSi alloy containing 15-55 wt.% Si or a CrAlSi alloy containing 70-80 wt.% Cr, or of an aluminum alloy such as an AlSi alloy preferably containing 10-25 wt.% Si; and (c) a dielectric external cover layer of Si or of Si3N4 and/or AlN.
Patent PT-971810-E (PT)
Inventor: SAVOIE MARC Y
IPC: B24B37/00
Filed: 1999-01-28
Abstract: The invention pertains to an improved method, a lapping tool head (82) and a lens polishing apparatus for carrying out the method, for polishing ophthalmic lenses (26). The apparatus has a lapping tool head (82), a flexible membrane (134) covering a lapping portion of the tool head (82), and pump and nozzle for pumping abrasive slurry over the lapping tool head. The new method comprises the conventional step of imparting an oscillatory movement to the lapping tool head (82) and contacting the lens surface with the lapping portion of the lapping tool head while an abrasive slurry is pumped over the lapping tool head (82). The improvement comprises the additional step of periodically undulating the membrane (134) for imparting a wave in that membrane such that the abrasive slurry can flow between the membrane and the lens surface. The lapping slurry is efficiently moved over the entire surface of the lens for improving the quality of the lenses (26) polished by this process.
Patent PT-1066660-E (PT)
Inventor: THORNER WOLFGANG B
IPC: H01R11/12
Filed: 1999-03-26
Abstract: The invention relates to a cable lug for connecting a cable end to a screw type terminal. The cable lug comprises a flat, u-shaped contact fork which is open toward the front and which merges into a fork shaft toward the rear. The fork shaft is provided with connection means for a cable end. At least one base plate configured as a signal conductor, at least one damping disk made of elastic material, and at least one cover plate are assembled in a stacked, sandwich-like manner in the area of the contact fork. In order to improve functional characteristics and durability, and more particularly to obtain an improved vibration-damping action, the invention provides that the cover plate extends over the sides of the damping disk.
Patent PT-1095545-E (PT)
Inventor: ANGELO GANDI
IPC: H05K3/46
Filed: 1999-07-08
Abstract: Thermal management device (13) comprises an anisotropic carbon (10) encapsulated in a polymeric encapsulating material (12) that improves the strength of the carbon. Thermal management device (13) comprises an anisotropic carbon (10) encapsulated in an encapsulating material (12) that improves the strength of the carbon. The encapsulating material may be a polyimide, an epoxy resin, polyurethane, polyester or any other suitable polymer. An independent claim is also included for fabricating a thermal management device by applying a coat of encapsulating material directly to a clean carbon surface.
Patent PT-1100803-E (PT)
Inventor: MINETTI PATRIZIA
IPC: A61P25/28
Filed: 1999-07-27
Abstract: Polycondensated heterocycles with a pyrrole[2,1-b][1,3]benzothiazepine structure of the following formula (I)where the groups are defined as in the description are disclosed. As compared to known antipsychotic agents, these compounds present substantial activity associated with a simultaneous reduction in unwanted extrapyramidal symptoms. These compounds can be formulated in pharmaceutical compositions for the treatment of psychoses such as, for example, schizophrenia.
Patent PT-1112169-E (PT)
Inventor: CARTER THOMAS G
IPC: B29C63/10
Filed: 1999-09-13
Abstract: A process of fabricating a composite vessel includes the steps of: A) fabricating a thermoplastic liner for the vessel; B) overlaying a layer comprising fiber and a thermoplastic material (preferably by winding commingled filaments, rovings or yarns) onto the thermoplastic liner to obtain a composite intermediate structure (the fiber and thermoplastic material can be heated if desired during the overlaying, e.g. winding, step); C) heating the composite intermediate structure in a mold while applying at least one force thereto tending to urge the composite intermediate structure against and into the shape of the interior walls of the mold; D) continuing step C) until the thermoplastic liner and the overlaid layer consolidate to form a composite vessel; E) cooling the mold and composite vessel until the composite vessel is solidified; and F) removing the formed composite vessel from the mold. The at least one force applied during step C) may be obtained by introducing gas pressure into the interior of the composite intermediate structure. Suitable materials for the thermoplastic material include: polyethylene, polypropylene, polybutylene terephthalate and polyethylene terephthalate. The resulting composite vessel exhibits superior mechanical and aesthetic properties.
Patent SG-63391-G (SG)
Title: Pressure-responsive downhole well tool
IPC: E21B34/10
Filed: 1991-08-01
Abstract: A downhole well tool, especially useful as a safety valve, comprises a housing (62) with a longitudinal bore (96), the bore including an operating element (100) (for example a ball valve operable to close the bore), and actuating means (104) so arranged that by changing the pressure in the well annulus or in the bore, the operating element is moved from a first to a second position, and in changing the pressure in the other of the well annulus and the bore, the operating element is moved from said second to a third position. Thus, in the case of a ball valve, the valve may be moved from an open to a closed position and then returned to an open position.
Patent IE-42419-L (IE)
Title: Triazolobenzocycloalkylthiadiazine derivatives
IPC: C07D249/12
Filed: 1976-02-03
Abstract: Novel triazolobenzocycloalkylthiadiazines, their preparation, and use as central nervous system antidepressants.
[US3954983A]
Patent IE-32878-L (IE)
Title: Powered rocking furniture
IPC: A47C3/02
Filed: 1969-03-19
Abstract: 1,253,595. Converting rotary into oscillating motion. M. TINETTI. 5 March, 1969 [11 July, 1968], No. 11588/69. Heading F2K. [Also in Division A4] A rocking chair 3 or other rocking furniture has a motor 6 connected via a reduction gear 7 to a linkage 9, 10 and mounted on a framework 5 pivotally supported (e.g. by links 4) from the chair &c. to which the linkage 9, 10 is connected so that rotation of the motor moves the centre of gravity of the motor, gear 7 and framework relative to the chair &c., to cause the latter to rock.
[GB1253595A]
Patent IE-36288-L (IE)
Title: Production of penicillins and cephalosporins
IPC: C07D499/00
Filed: 1972-04-13
Abstract: Antibiotics of the general formula (I): (where Y = and R = H, halogen, azido, acyloxy, alkoxy, aryloxy, or SR' (R' = alkyl aryl or heterocycle), R1, Ri = H, opt. substd. alkyl, aryl aralkyl, aryloxy, cycloalkane or heterocycle, or R1 + R2 form a ring, R3 = H, halogen, OH, NH2, NHalk, azido, CN, Oalk, Salk, aryloxycarbonyl, aralkyloxycarbonyl or alkoxycarbonyl, n = 0 or 1) are prepd. from corresp. amino-cpds. (e.g. 6-APA) by protection with trivalent phosphorus halides, reacting the inters. with active derivs. of carboxylic acids and removing the protective gp. by solvolysis.
[FR2133686A1]
Patent IE-40835-L (IE)
Title: Tensioning device
IPC: B60R22/46
Filed: 1975-03-18
Abstract: A tensioning device which also provides for damped return movement and subsequent retensioning, such as for use with a vehicle safety belt comprises a casing, a piston movable within the casing by high pressure gases issuing from a pyrotechnic charge, a rod attached to the piston and carrying an attachment buckle for the belt, and a piston jamming mechanism for preventing movement of the piston in one direction but allowing damped movement thereof in the opposite direction, the piston and/or any of the other additional pistons possibly included in the device, having a part slidable relative thereto with a compression spring located therebetween for urging the piston and associated part axially apart at the end of damping. The pistons and associated parts form concentric members, the springs being located between them and abutting against an inwardly directed shoulder on the piston and external shoulder on the parts.
[US3957281A]
Patent IE-830823-L (IE)
Title: Process and reagent for the determination of low density¹lipoproteins in body fluids
IPC: C12Q1/60
Filed: 1983-04-11
Abstract: 1. Process for the determination of low density lipoproteine (LDL) in body fluids, characterised in that one adds to the high density lipoproteins (HDL) antibodies, which have been obtained with purified complete (HDL) fraction as immunogen, separates off insolubles formed and determines the (LDL) or one of its components in the supernatant.
Patent IE-45145-L (IE)
Title: Immunostimulating agent
IPC: C12N9/24
Filed: 1977-05-10
Abstract: The invention relates to an agent for stimulating the immunologic reactivity, comprising a mixture of an antigen and neuraminidase.
[US4510129A]
Patent FI-823435-L (FI)
Inventor: DAVIS LARRY
IPC: C07D471/10
Filed: 1982-10-08
Abstract: Novel 8-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyll-1-phenyl-1,2,8-triazaspiro[4.5]decan-4-ones, process for the preparation thereof, and their use for treating psychoses and alleviating pain are described.
Patent FI-851054-L (FI)
Inventor: OLSON HANS ERIK EVALD
IPC: F25B47/00
Filed: 1985-03-15
Abstract: The present invention relates to a method for defrosting one or more evaporators (7) in a cooling system (1) and/or one or more evaporators (19) in a freezing system (2), whereby cooling-medium liquid (4) is fed to the evaporators (7, 19) of said cooling and freezing systems (1, 2) respectively, via an inlet conduit (6 and 18 respectively) and evaporated in respective evaporator (7, 19) to cooling-medium vapour (10), which through an outlet conduit (11 and 22 respectively) is fed to one or more compressors (13 and 24 respectively) in the cooling and freezing systems respectively, for compression to heated cooling-medium vapour (14), which from the compressor or compressors (13) of the cooling system (1) is fed to the evaporator or evaporators (19) of the freezing system (2) for defrosting thereof and from the compressor or compressors (24) of the freezing system (2) to the evaporator or evaporators (7) of the cooling system (1) for defrosting thereof. 
<??>The invention also relates to a simple device for the implementation of said method. Said device is characterized by a connecting conduit (15), common to the compressors (13 and 24) of the cooling and freezing systems (1, 2), for feeding cooling-medium vapour (14) from the compressor or compressors (13) of the cooling system (1) to the evaporator or evaporators (19) of the freezing system (2) via a conduit branch (33) and the inlet conduit (18) to the evaporator or evaporators of the freezing system, whereby said vapour (14) is fed to said inlet conduit (18) downstream of an expansion valve (21) located therein, whereby said common connecting conduit (15) is further provided to feed, via a conduit branch (34) and the inlet conduit (6) to the evaporator or evaporators (7) of the cooling system (1), cooling-medium vapour (14) from the compressor or compressors (24) of the freezing system (2) to the evaporator or evaporators (7) of the cooling system (1) and whereby said vapour (14) is fed to said inlet conduit (6) downstream of an expansion valve (9) in said conduit (6).
Patent IE-791109-L (IE)
Title: Treating non-woven fabric
IPC: D04H1/4218
Filed: 1979-08-08
Abstract: A process for improving the physical properties of non-woven fabrics, particularly glass wool, for the purpose of rendering said fabrics more receptive to print comprises applying plastisol, having a Newtonian viscosity between 4 and 30 poise, to one surface of the non-woven material, and pressing the impregnated fabric with a roller against a cylinder heated to 130 and 180 DEG C. The impregnated side of the fabric is maintained in contact with the cylinder and at least partially covers said cylinder.
[GB2023200A]
Patent IE-811180-L (IE)
Title: Fuel from waste material
IPC: C10L5/46
Filed: 1981-05-27
Abstract: A method of producing a generally homogeneous fuel having a generally consistent particle size and calorific content from a heterogeneous waste material having components of diverse moisture contents, calorific values and micro-organism contents comprises: passing the waste material through a rotating drum; controlling the volume of waste material in the drum, the speed of rotation of the drum and the rate of flow of the material through the drum so as to obtain therein a residence time and a component collision frequency and intensity sufficient to obtain: (a) transfer of moisture between the components via mutual component contact, (b) breakdown of said components into small particles, and (c) intimate admixture of the small particles. The residence time is controlled to be sufficiently short so as to minimise micro-organism growth and activity and substantially to prevent any appreciable temperature rise. The fuel is obtained from the admixture of particles by separating those particles less than a predetermined size.
[GB2082628A]
Patent IE-881284-L (IE)
Title: Piperidine derivatives
IPC: C07D401/04
Filed: 1988-04-29
Abstract: A cardiac antiarrhythmic agent of the formula:- or a pharmaceutically-acceptable salt thereof: wherein R is R<3>SO2NH-, R<3>CONH- or R<1>R<2>NSO2-; R<1> and R<2> are each independently H or C1-C4 alkyl; R3 is C1-C4 alkyl, C3-C7 cycloalkyl or -NR<1>R<2> where R<1> and R<2> are as defined above; and Het is either (a) a 2-, 3- or 4-pyridyl group optionally substituted by a C1-C4 alkyl or an amino group, or (b) a 2-imidazolyl group optionally substituted by one or two C1-C4 alkyl groups.
Patent IE-37987-L (IE)
Title: Accelerator for gypsum board
IPC: C04B24/08
Filed: 1973-08-09
Abstract: 1389429 Plaster compositions BPB INDUSTRIES Ltd 1 Aug 1973 [7 Nov 1972] 51368/72 Heading C1H An accelerator for use in making gypsum board comprises gypsum and a C 12 (or more) fatty acid or its salt; e.g. stearic, palmitic, oleic and linileic acids or their A.M. or A.E.M. salts. The accelerator has a specific area of at least 800 m.<SP>2</SP>/kg.
[GB1389429A]
Patent IE-45665-L (IE)
Title: Acyl substituted benzimidazole-2-carboxylic acid¹derivatives.
IPC: C07D235/14
Filed: 1977-08-26
Abstract: New heterocyclylcarboxylic acid derivatives which are acylated in the nucleus, especially benz-acyl-benzimidazole-2-carboxylic acid derivatives of the formula <IMAGE> (I) in which R is a free, esterified or amidated carboxyl group or a free, etherified or esterified hydroxymethyl group, R1 is an aliphatic, cycloaliphatic, aromatic, araliphatic, heterocyclic or heterocyclic-aliphatic radical, R2 is hydrogen or an aliphatic radical and Ph is a 1,2-phenylene group containing the radical R1-C(=O)-, with the proviso that R1 contains at least 2 carbon atoms if Ph is otherwise unsubstituted, R2 is ethyl and R is acetoxymethyl, and salts of such compounds having salt-forming properties, are useful as anti-allergic agents.
[US4141982A]
Patent IE-781849-L (IE)
Title: Moulded meat
IPC: A22C17/00
Filed: 1978-09-13
Abstract: A method and apparatus for the production of molded meat or meat-like products, for example sausages. The surface of the product is treated with a fluid, which could be for coloring or flavoring purposes, but is advantageously e.g. an edible acid adapted to react with protein in the product to form a cohesive surface and enable the use of a separate skin to be avoided. The mold includes a permeable wall, for example of sintered stainless steel, through which the fluid can be introduced. In a preferred embodiment the wall is defined by a hollow cylinder disposed in a non permeable housing containing the fluid. An end cap closes one end of the cylinder and a plunger compresses the material to form the product. At the same time additional fluid is injected through a nozzle into the housing, to cause a corresponding quantity of fluid to pass through the cylinder wall and treat the surface of the product.
[US4280803A]
Patent IE-44384-L (IE)
Title: Cyclopentanol derivatives
IPC: A61P43/00
Filed: 1976-08-27
Abstract: Novel cyclopentanoic acid derivatives of the formula <IMAGE> I wherein R is selected from the group consisting of <IMAGE> and -CH2OH, R' is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms and a non toxic, pharmaceutically acceptable cation and R1 is selected from the group consisting of hydrogen, 2-tetrahydropyranyl, branched or straight chain, saturated or unsaturated alkyl of 1 to 4 carbon atoms and <IMAGE> and R2 is selected from the group consisting of straight or branched chain alkyl of 1 to 12 carbon atoms and phenyl with the alkyl and phenyl being optionally substituted with -COOA wherein A is selected from the group consisting of hydrogen, alkali metal, ammonium ion, ion of an organic amine, alkyl and haloalkyl of 1 to 7 alkyl carbon atoms with the proviso that R1 is not hydrogen or 2-tetrahydropyranyl when R is a carboxylic group, and the OH and R groups on the ring and OR1 group on the chain may be in either of the two possible positions about the carbon atom to which they are attached having analgesic, anti-inflammatory and smooth muscle relaxant activity.
[US4072755A]