baber/WOPTO huggingface dataset:
Patent NZ-602018-A (NZ)
Title: Bisaryl-bonded aryltriazolones and use thereof
Inventor: KOLKHOF PETER
IPC: C07D417/06
Filed: 2011-02-25
Abstract: Disclosed herein are bisaryl-bonded 5-aryl-1,2,4-triazolone compounds of general formula (I), wherein the substituents are as defined with in the specification, processes for their preparation, compositions comprising said compounds and uses thereof. These triazolone compounds are useful in the treatment or prevention of acute and chronic heart failure, hypervolemic and euvolemic hyponatremia, cirrhosis of the liver, ascites, edema and the syndrome of inadequate ADH secretion (SIADH).
Patent NZ-603277-A (NZ)
Title: Lifting anchors
Inventor: WOOD ALISTAIR M
IPC: E04G21/16
Filed: 2012-10-25
Abstract: 603277 Disclosed is a lifting anchor for incorporation into a concrete panel prior to casting to provide a lifting point by which the panel can subsequently be lifted. The anchor comprises a first lifting head (2) for releasable engagement with a lifting clutch in an edge lifting configuration and a second lifting head (16) for engagement with a lifting clutch in a face lifting situation. The anchor therefore provides the option of lifting a concrete panel from the face side, which avoids the potential for damage to the panel when lifting from the edge side.
Patent NZ-603600-A (NZ)
Title: A post
Inventor: JAMES DALLAS REX
IPC: E01F15/06
Filed: 2012-11-14
Abstract: A post (100) is disclosed with apertures (101) on alternate sides to receive and retain at least one cable of a road barrier. Each side of the post has the same number of apertures (101) and each aperture has an opening in the form of a mouth. The mouth has a top surface has a greater angle at a distal region (102) than at a proximate region (103). The mouth shape is configured to reduce the travel path and/or frictional contact with the cable as it is ejected from the mouth following a collision.
Patent NZ-607608-A (NZ)
Title: Method of producing pancreatic hormone-producing cells
Inventor: HOSOYA MASAKI
IPC: A61K35/39
Filed: 2011-08-08
Abstract: NZ 607608 Disclosed is a method of producing pancreatic hormone-producing cells, comprising subjecting stem cells to the following steps: (1) Cultivating stem cells in a medium containing a Rho kinase inhibitor, (2) Cultivating the cells obtained in the aforementioned step (1) in a medium containing a GSK3 inhibitor, (3) Cultivating the cells obtained in the aforementioned step (2) in a medium containing GSK3 inhibitor and an activator of activin receptor-like kinase-4,7, (4) forming a cell mass from the cells obtained in the aforementioned step (3), and cultivating the cell mass in a suspension state in a medium, (5) a step of cultivating the cells obtained in the aforementioned step (4) in a medium containing a retinoic acid receptor agonist, an inhibitor of AMP-activated protein kinase and/or activin receptor-like kinase-2,3,6, an inhibitor of activin receptor-like kinase-4,5,7 and a cell growth factor, (6) cultivating the cells obtained in the aforementioned step (5).
Patent NZ-623489-A (NZ)
Title: Acoustic device and components
Inventor: LAM KWAN FOO
IPC: H04R9/06
Filed: 2014-04-04
Abstract: A planar magnetic speaker is disclosed. The speaker makes use of Halbach arrays to produce a stronger magnetic field (32) which increases the sensitivity of the device for any given individual magnet strength. Modules (66) are assembled from opposing Halbach arrays in holders (40) .The speaker as whole is assembled from the modules attached to a frame (50) having a film (60) bearing conductors (62) suspended there between. The connection pattern (77, 79) of the conductors is such that the alternating magnetic field direction of the Halbach arrays is countered so that the film is uniformly deflected on application of an electric current. The conductors are arranged in pairs (78) which are aligned with the Halbach array so that current direction is reversed in each successive pair across the film to match the magnetic field reversal across the array. A system of swappable speaker drivers is also disclosed.
Patent NZ-623576-A (NZ)
Title: Tfpi inhibitors and methods of use
Inventor: HARTMANN RUDOLF
IPC: C40B40/10
Filed: 2011-02-11
Abstract: Disclosed is a peptide that binds TFPI comprising (a) an amino acid sequence having at least 85% identity to SEQ ID NO: 1334 or (b) an amino acid sequence comprising one or two substitution(s), deletion(s) or insertion(s) of the amino acid sequence of (a); wherein the sequence is as defined in the specification. Also disclosed is the use of the peptide for treating a subject suffering from a blood coagulation disorder or at risk of suffering from a blood coagulation disorder.
Patent NZ-623718-A (NZ)
Title: A multi-cell battery assembly
Inventor: KRISTOFEK GRANT WILLIAM
IPC: H01M10/6557
Filed: 2012-10-26
Abstract: A cooling assembly for a muliti-cell battery is disclosed. The assembly includes a plurality of battery cells (102), first and second fluid manifolds (112) and a plurality of corrugated flow plates (160) interleaved with the plurality of battery cells (102). Each the flow plates (160) extends from the first manifold (112a) to the second manifold (112b) to provide an array of flow channels for carrying fluid from the first manifold to the second manifold. Each plate (160) is an extruded plastic structure comprising first and second fluid impermeable sheets and a plurality of parallel ribs between and connecting the first and second sheets (see Fig. 4,). The plurality of ribs forms an array of flow channels for coolant fluid.
Patent NZ-631071-A (NZ)
Title: Methods and compositions for modulating apolipoprotein(a) expression
Inventor: FREIER SUSAN M
IPC: C12P19/34
Filed: 2013-05-23
Abstract: Disclosed is a compound comprising a modified oligonucleotide consisting of 20 linked nucleosides and having a nucleobase sequence comprising at least 12 contiguous nucleobases of the nucleobase sequence of SEQ ID NO: 58, wherein the modified oligonucleotide comprises: a gap segment consisting of ten linked deoxynucleosides; a 5’ wing segment consisting of five linked nucleosides; a 3’ wing segment consisting of five linked nucleosides; wherein the gap segment is positioned between the 5’ wing segment and the 3’ wing segment, wherein each nucleoside of each wing segment comprises a 2’-O-methoxyethyl sugar, and wherein each cytosine residue is a 5-methylcytosine.
Patent NZ-705120-A (NZ)
Title: Multiplex pipe and system for recovering steam from geothermal wells
Inventor: SUZUMURA KEITA
IPC: F24J3/08
Filed: 2013-05-28
Abstract: Provided is a multiplex pipe and system for recovering steam from geothermal wells capable of resolving all of the various problems with a neutralizing pipe capable of being formed by coating the inner face of a single acid resistant pipe with an alkaline resistant film. A multiplex pipe (10) for recovering steam from a geothermal well (GT) comprises an external casing pipe (1), and a duplex pipe (4) freely sliding relative to the interior of the casing pipe (1) and having a first gap (5) with the inner face of the casing pipe (1), and comprising an acid resistant exterior pipe (2) and an alkaline resistant inner pipe (3) and having a second gap (6) between the exterior pipe (2) and inner pipe (3), wherein hot acidic water is neutralized by an alkaline chemical solution injected, via a space (7) in the inner pipe (3), into the hot acidic water accumulated in an acidic geothermal well (GT), and flashed steam is recovered, via the first gap (5), by ejecting the neutralized hot water (V) onto the ground.
Patent NZ-712219-A (NZ)
Title: A method and apparatus for brewing a coffee drink
Inventor: DAY NEIL
IPC: A47J31/00
Filed: 2014-03-11
Abstract: Numerous methods and devices exist for placing ground coffee beans in contact with hot water and separating the remaining solid grounds to produce coffee drinks. Properly adjusting the fineness of coffee grinds and other brewing parameters to achieve the desired flavor generally requires trial and error, and often a trained “barista.” As such a method for controlling brewing of a coffee drink is disclosed. The method comprises receiving, with a processor, an identifier for the coffee drink, wherein the identifier is associated with a brew parameter used to make the coffee drink. The brew parameter includes a size of grounds of coffee beans. A grinder is set to a first setting based on the size of the grounds of the coffee beans of the brew parameters. The coffee beans are grinded with the grinder set to the first setting to produce first ground coffee beans. An image of a calibration mark and a portion of the first ground coffee beans is obtained. A ground size of the first ground coffee beans is determined based on the calibration mark. The grinder is set to a second setting based on the size of the ground of the coffee beans associated with the identifier and the determined ground size of the first ground coffee beans. The first ground coffee beans with the grinder set to the second setting to produce second ground coffee beans.
Patent NZ-717601-A (NZ)
Title: Method and server for searching for data stream dividing point based on server
Inventor: YU CHUANSHUAI
IPC: G06F17/40
Filed: 2014-02-27
Abstract: An embodiment of the present invention provides a server-based method for searching for a data flow break point. In the embodiment of the present invention, data stream break points are searched for by determining whether at least part of data in a window of M windows meets a predetermined condition. If at least part of data in one window fails to meet the predetermined condition, N*U lengths are skipped and a next potential break point is obtained. The data flow break point search efficiency is improved.
Patent NZ-720807-A (NZ)
Title: Fused heterocyclic compounds as ion channel modulators
Inventor: GRAUPE MICHAEL
IPC: C07D471/04
Filed: 2014-12-03
Abstract: The present disclosure relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula I: wherein X, Y, Z, R2, R3, R4, p and q are as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.
Patent NZ-724866-A (NZ)
Title: Insulin-like growth factor 1 receptor -specific antibodies and uses thereof
Inventor: KEMMERICH Kristin
IPC: C07K16/46
Filed: 2014-12-04
Abstract: The blood-brain barrier (BBB) prevents transport of molecules larger than 500 Daltons from blood to brain. Receptor-mediated transcytosis (RMT) facilitates transport across the BBB of specific molecules that bind receptors on brain endothelial cells that form the BBB. An insulin-like growth factor 1 receptor (IGFlR)-binding antibody or fragment thereof is identified that transmigrates the BBB by RMT. The antibody or fragment is used to deliver a cargo molecule across the BBB, wherein the cargo molecule may be a therapeutic or detectable agent. The antibody is a camelid VHH, prepared by immunizing a llama with a 933-amino acid IGF1R polypeptide. Humanized forms of the camelid VHH are also generated.
Patent NZ-731633-A (NZ)
Title: Antibodies against cd73 and uses thereof
Inventor: LONBERG NILS
IPC: C07K16/30
Filed: 2015-11-19
Abstract: The present disclosure provides isolated monoclonal antibodies, particularly human antibodies, that bind to human Cluster of Differentiation 73 (CD73) with high affinity, and inhibit the activity of CD73, and optionally mediate antibody dependent CD73 internalization. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells and methods for expressing the antibodies of the disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the disclosure are also provided. The disclosure also provides methods for inhibiting the growth of a tumor cell expressing CD73 using the antibodies of the disclosure, including methods for treating various cancers. In a particular embodiment the CD73-binding antibody comprises the heavy chain CDRs NYGMH, VILYDGSNKYYPDSVKG and GGSSWYPDSFDI; and light chain CDRs RASQGISSWLA, AASSLQS and QQYNSYPLT; and comprise a heavy chain constant region comprises an IgG2 hinge and IgG2 CH1 domain.
Patent NZ-736509-A (NZ)
Title: Apparatus and process for packaging a product
Inventor: CAPITANI STEFANO
IPC: B65B31/02
Filed: 2016-05-19
Abstract: A process and apparatus (1) for packaging a product (P) arranged on a tray (4) is disclosed. The apparatus comprises a packaging assembly (8) configured for tightly fixing one or more film sheets to one or more trays. The packaging assembly includes a lower tool (22) defining a prefixed number of seats (23) for receiving the trays and an upper tool (21) facing the lower tool and cooperating with the upper tool to define a packaging chamber (24). The packaging assembly (8) is configured to operate at least in a first operating condition, where said packaging chamber (24) is open, and in a second operating condition, where said packaging chamber (24) is hermetically closed. First injection apertures (90) are positioned in corner regions of the seat and are configured to inject streams of gas in a direction substantially parallel to and above the flange (4c) of a tray (4) positioned in said seat. The process includes the step of activating injection of a plurality of streams of gas through said first apertures (90) in order to form a controlled atmosphere inside the tray before closing the tray with the film. The apparatus and/or process aim to efficiently and accurately position a film and/or a tray in a packaging process and to avoid or at least reduce some disadvantages associated with packaging such as film and/or tray misplacement and/or uncontrolled deformation.
Patent NZ-745001-A (NZ)
Title: Improved treatment of implants with phosphonic acid compounds
Inventor: BUCHINI SABRINA
IPC: A61L27/28
Filed: 2017-02-13
Abstract: The present invention relates to a process of treating an implant, comprising a step of treating the surface of the implant with at least one phosphonic acid compound or a pharmaceutically acceptable salt, ester or amide thereof under sonication at a temperature of about 50°C to about 90°C. This process is highly advantageous in that it allows the formation of a monolayer of the phosphonic acid compound on the implant surface, having a particularly dense surface coverage which, in turn, results in an improved implant biocompatibility and improved osseointegration. The invention further relates to a surface-treated implant obtainable by this process and, in particular, it provides an implant having a surface made of a metal, a metal alloy or a ceramic, wherein a phosphonic acid compound or a pharmaceutically acceptable salt, ester or amide thereof is bound to the surface of the implant and forms a monolayer having an implant surface coverage, in terms of the ratio of the phosphorus content to the metal content as determined by X-ray photoelectron spectroscopy (XPS), of at least 70% of a reference maximum surface coverage.
Patent NZ-745221-A (NZ)
Title: Container and lid
Inventor: FREEDMAN JONATHAN R
IPC: B65D53/02
Filed: 2017-03-06
Abstract: A moisture tight container 300 includes a container body 301 and a lid 320 preferably linked to the body 301 by a hinge 340. The body 301 and lid 320 include at least a first seal 462 and a second seal 464 in series to provide a moisture tight seal 460 between the body 301 and the lid 320. The first seal 462 includes mating of thermoplastic-to-thermoplastic sealing surfaces of the body 301 and lid 320 respectively. The second seal 464 includes mating of thermoplastic-to-elastomeric sealing surfaces of the body 301 and lid 320, respectively, or of the lid 320 and body 301 respectively.
Patent NZ-749437-A (NZ)
Title: Processes and intermediates for making a jak inhibitor
Inventor: LIU PINGLI
IPC: C07D401/14
Filed: 2014-03-05
Abstract: The present invention provides a compound of Formula VII, or a salt thereof; wherein: R1 and R2 are each independently H or C1-6 alkyl; or R1 and R2, together with the two oxygen atoms to which they are attached and the boron atom to which the oxygen atoms are attached, form a 5- to 6-membered heterocycloalkyl ring, which is optionally substituted with 1, 2, 3, or 4 C1-4 alkyl groups. The compound of Formula VII is used in a process for preparing the JAK inhibitor { 1-{ 1-[3-fluoro-2-(trifluoromethyl)isonicotinoyl]piperidin-4-yl} -3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl} acetonitrile.
Patent NZ-769669-A (NZ)
Title: Additive manufacturing apparatus, system, and method
Inventor: KNECHT FREDERICK
IPC: B29C64/218
Filed: 2019-04-05
Abstract: An apparatus for producing a three-dimensional object using a resin in a layer-by-layer technique uses a roller or other applicator to carry a layer of the resin to an application site, an exposure device to emit electromagnetic waves to apply the layer to the object to build the object, and further including an initial exposure with emitted electromagnetic waves to at least partially solidify the layer of the resin prior to the roller carrying the layer to the application site. Partially solidifying the resin prior to the roller can enable excess resin to be removed from the layer prior to building the object, and can allow for build verification between the first exposure and the second exposure.
Patent PT-109529-A (PT)
Title: Muro de blocos modulares encaixáveis de betão
Inventor: PAULO PRIMITIVO PEREIRA
IPC: E02D29/02
Filed: 2016-07-12
Abstract: O PRESENTE INVENTO REFERE-SE A UM NOVO PROCESSO DE FABRICO E CONSTRUÇÃO DE MUROS (8)PARA SUPORTE DE TERRAS FEITOS ATRAVÉS DE BLOCOS DE BETÃO MODULARES E ENCAIXÁVEIS. A GEOMETRIA DOS BLOCOS E SUAS INTERLIGAÇÕES PERMITEM FAZER MUROS COM CURVAS EM PLANTA, COM GRANDE CURVATURA, COM RAIO ATÉ 6M. OS BLOCOS SÃO DISPOSTOS SEMPRE SEGUNDO O ALINHAMENTO DO MURO E SÃO ENCAIXÁVEIS DE MODO A TER JUNTAS DESENCONTRADAS QUER NO PLANO DO ALÇADO DO MURO, QUER EM PLANTA. OS MUROS RESULTANTES PODEM SER APLICADOS COM PARAMENTO VERTICAL OU COM UMA LIGEIRA ROTAÇÃO OU COM SOCALCOS NA FRENTE.
Patent PT-110068-A (PT)
Title: Cápsula para rolha de cortiça flangeada, rolha capsulada compreendendo a referida cápsula e processo de produção da rolha capsulada.
Inventor: RICARDO MANUEL CORREIA DOS SANTOS RIBEIRO
IPC: B65D39/00
Filed: 2017-05-10
Abstract: A INVENÇÃO REFERE-SE A UMA CÁPSULA (1) PARA ROLHA DE CORTIÇA FLANGEADA, A CÁPSULA (1) POSSUINDO UM CORPO (2) QUE COMPREENDE UM TOPO (3) E UMA CAVIDADE (4) DENTRO DA QUAL ESTÃO DISPOSTAS PELO MENOS DUAS ESTRIAS (5) ANTIRROTAÇÃO, E A CÁPSULA COMPREENDENDO AINDA UMA CÂMARA (6) DE RETENÇÃO AXIAL DISPOSTA NO INTERIOR DA REFERIDA CAVIDADE (4), EM QUE A CÂMARA (6) DE RETENÇÃO ESTÁ CONFIGURADA PARA RECEBER E RETER AXIALMENTE UMA FLANGE DE UMA ROLHA DE CORTIÇA FLANGEADA. A INVENÇÃO TAMBÉM SE REFERE A UMA ROLHA CAPSULADA COMPREENDENDO UMA ROLHA FLANGEADA, CUJA FLANGE ESTÁ ACOPLADA À CÁPSULA (1) DA INVENÇÃO. A INVENÇÃO REFERE-SE AINDA AO PROCESSO DE PRODUÇÃO DA REFERIDA ROLHA CAPSULADA.
Patent PT-115784-A (PT)
Title: Reator electroquímico avançado para a remoção de micropoluentes e microrganismos a partir de matrizes aquosas
Inventor: ANA RITA LOURINHO FERREIRA
IPC: C01G55/00
Filed: 2019-09-18
Abstract: O PRESENTE PEDIDO DESCREVE UM REATOR ELETROQUÍMICO AVANÇADO PARA A REMOÇÃO DE MICROPOLUENTES E MICRORGANISMOS DE MATRIZES AQUOSAS COM ELEVADA EFICIÊNCIA. O REATOR ATUALMENTE DESCRITO COMPREENDE, PELO MENOS, QUATRO ELÉTRODOS COLOCADOS EM UMA CONFIGURAÇÃO PARALELA EM TODA A CÂMARA DO REATOR COM A SUA POLARIZAÇÃO INTERCALADA ENTRE O ÂNODO E O CÁTODO. OS ELÉTRODOS DO PRESENTE REATOR SÃO FEITOS DE UM MATERIAL DE FITA FLEXÍVEL COM FORMA DE MALHA CIRCULAR DE ÓXIDO DE METAL MISTO, E CONFIGURADOS EM FORMAS SELECIONADAS A PARTIR DE UMA FORMA CIRCULAR, FORMA DE MOLA HELICOIDAL OU FORMA DE DUPLA HÉLICE. ESTE REATOR PROPORCIONA UMA ÁGUA RESIDUAL MAIS SEGURA COMO PRODUTO FINAL A SER REUTILIZADO, POR EXEMPLO, NA IRRIGAÇÃO OU PARA UMA DESCARGA NAS MASSAS DE ÁGUA, EVITANDO A PROPAGAÇÃO DA CONTAMINAÇÃO E EFEITOS NOCIVOS PARA O ECOSSISTEMA E CADEIA ALIMENTAR.
Patent RU-94000640-A (RU)
Inventor: KRASNOV A F
IPC: A61B17/56
Filed: 1994-01-06
Abstract: FIELD: medicine; methods for surgical treatment of diseases of the locomotor system, particular, patients ill with neuromuscular diseases and having a tip foot. SUBSTANCE: achillotom is introduced to the middle of distal end of the Achilles tendon, its tip is put under the tendon through the half of its length. The tendon is punctured from its front to the rear, and, without injuring the skin (a mark is made above the achillotom tip) the tendon is dissected longitudinally from the top to bottom in the sagittal plane and the half of its portion in the frontal plane. The second puncture of achillotom is made somewhat lower the muscle belly into the middle of the tendon. The tool is driven under the tendon and its tip is brought out to the made mark. Without injuring the skin, the tendon is dissected longitudinally from the bottom upward to connected two dissections into one in the sagittal plane and the opposite half transversely in the frontal plane. A raspatory is introduced through skin puncture at the calanean tuber and the cicatrixes between the skin and the tendon are dissected hypodermically. The foot is brought out at the right angle to the crus. EFFECT: reduced injury caused by operation and decreased number of postoperative complications and reduced time taken for operation, number of surgeons taken part in the operation, and cut down consumption of operation materials. 1 cl, 3 dwg
Patent RU-94012903-A (RU)
Inventor: MAKUSHIN V D
IPC: A61B17/56
Filed: 1994-04-13
Abstract: FIELD: medicine; surgical methods of management of the locomotor system applicable in orthopedics and traumatology of posttraumatic flexion contracture of the elbow joint. SUBSTANCE: method for elimination of flexion contracture of elbow joint includes use of the apparatus of perosseous fixing. Wires are driven through the elbow tip and fixed to semiring installed with inclination. The apparatus supports are interconnected. Partial osteotomy of the base of the elbow tip through the skin incision on the rear surface is performed. Elbow tip is bent due to trampling up to the desired change of the curvature of the trochlear notch. After suturing the wound, applied round the wires and to wound are aseptic dressings. Next day after operation functional movements of elbow joint are started with the help of the perosseous fixation apparatus. EFFECT: higher efficiency.
Patent RU-94021333-A (RU)
IPC: C30B15/02
Filed: 1994-06-10
Abstract: FIELD: crystal growing by Chochralsky method. SUBSTANCE: apparatus, providing continuous makeup of a melt in a crucible by pelletized (broken) initial material, includes a growing chamber with the crucible for the melt and means for feeding the initial material into the crucible. The means for feeding the initial material has two chambers, between which an accumulating hopper is arranged. The hopper is provided by a pickup for detecting a level of the material and a slide gate. A rotary container is placed in one of these chambers and a feeder is placed in the other chamber. EFFECT: enhanced efficiency, reproducibility of growing process, possibility of growing crystals, having practically unlimited size. 1 cl, 1 dwg
Patent RU-94022702-A (RU)
Inventor: TRUSHCHEV A G
IPC: E04G17/14
Filed: 1994-06-10
Abstract: FIELD: civil engineering, may be used to erect smooth monolithic reinforced concrete floors in buildings and constructions using shied-shaped concrete form of usual or light concrete. SUBSTANCE: shield-shaped permanent concrete form for monolithic floors has plates with connecting members in the form of bevels being widened symmetrically to interconnect these plates. Connecting members with bevels are placed on the same axes in plate plane in points of opposite sides of concrete form plates and along all thickness. Internal connecting members are made with bevels being widened inward. Outer connecting members have bevels that are widened respectively outward. EFFECT: butt joining of flat concrete form plates. 6 cl, 10 dwg