baber/WOPTO huggingface dataset:
Patent EP-4074725-A2 (EP)
Inventor: SHIN SEUNG-SHICK
IPC: G01N33/544
Filed: 2020-12-02
Abstract: The present invention relates to a switching binder binding to an antigen-binding portion of an antibody, a preparation method thereof, and a pharmaceutical composition, an assay kit, and an antigen and antibody assay method, each utilizing the same. A switching binder according to an embodiment of the present invention includes an amino acid sequence selected from framework regions of a heavy chain or a light chain, which constitutes an antigen-binding portion of an antibody, wherein the amino acid sequence includes, in addition to the heavy chain or the light chain, a first antibody-binding portion or a second antibody-binding portion that binds to a framework region of a heavy chain or a light chain, which constitutes the antigen-binding portion, the amino acid sequence being able to bind specifically to the antigen-binding portion of the antibody and then be separated from the framework region when a target antigen is provided.
Patent EP-3855475-A2 (EP)
Inventor: HAKALA JANI
IPC: B05B1/00
Filed: 2017-09-11
Abstract: The invention relates to a multi-mode ionization device (MID, 300B) in which two types of reagent ions that are generated by ionizing two reagents (R1, R2) in two separate reagent ion sources (302) are introduced into a reaction chamber (CH1) in which they are mixed with analytes (S) that are introduced into the reaction chamber as an analyte flow (301). The analyte (S) is ionized by chemical ionization by reactions with the reagent ions.
Patent EP-3854271-A2 (EP)
Inventor: SHAW GAIL
IPC: A47G23/03
Filed: 2015-05-14
Abstract: A protective article comprising a sheet with a first surface and at least one adhesive portion arranged on the first surface. The adhesive portion comprises a water-based adhesive that allows the sheet to be non-permanently adhered to an object.
Patent EP-4121138-A2 (EP)
Title: Blood separation system and blood products
Inventor: NIERICH ARNO PIETER
IPC: A61K35/14
Filed: 2021-03-22
Abstract: A blood filtering apparatus for recovering blood components from blood comprises an inlet for the blood; a cell filter configured for filtering a portion of the blood and retaining as a retentate a fraction of the blood containing red blood cells and platelets and passing as a filtrate a fraction of the blood, in particular mainly as plasma, containing platelets and being depleted of red blood cells. The cell filter has a pore size in a range of 2,0-3,0 micron. Further, a method and a blood product are provided.
Patent EP-4146083-A2 (EP)
Inventor: JI MI JUNG
IPC: A61B10/00
Filed: 2021-05-07
Abstract: Provided herein are devices, kits, systems, and methods for collecting samples for analytical analysis and the safe disposal of sample collection devices after their use. The devices, kits, systems, and methods find use, for example, for disposing of biohazard materials by users in settings that may not be equipped with the professional biohazard disposal systems of laboratories, hospitals, and medical clinics.
Patent EP-4265601-A2 (EP)
Title: Use of benzisoselazole derivative for anti-coronavirus and control of interstitial lung disease (ild) related to coronavirus
Inventor: ZENG HUIHUI
IPC: C07D293/12
Filed: 2021-07-06
Abstract: The present invention provides the use of the benzisoselazole derivative of formula (I) for preparing an anti-coronavirus drug or a drug for treating diseases caused by coronaviruses. The benzisoselazole derivatives of the present invention can effectively inhibit the activity of 2019-nCoV 3CLpro proteolytic enzyme, thus inhibiting the activation of 2019-nCoV RNA polymerase, inhibiting virus replication, while also effectively treating interstitial lung disease (ILD) caused by coronavirus.
Patent EP-4177244-A2 (EP)
Title: Process and intermediates for the preparation of pyroxasulfone and fenoxasulfone
Inventor: BARDA BARDA
IPC: C07D231/20
Filed: 2020-07-10
Abstract: The invention relates to a process for preparing immediate precursors for pyroxasulfone and fenoxasulfone preparation of the formula (I). The process comprises a bromination reaction of a benzylic position without light irradiation (step a), followed by thoination reaction, which substitutes the bromine atom (step b) and after the protecting group is removed, and the revealed thiol or thiolate reacts with a substituted isoxazoline bearing a leaving group at the 3-position (step c).
     
wherein 
Y = protecting group 
     In another variant of the invention the pyroxasulfone or fenoxasulfone immediate precursor is synthesized from the arylmethyl bromide by first forming a carbon-sulfur bond at the 3-position of a 2-isoxazoline through displacement of a leaving group at the 3-position (particularly acid derived residues such as phosphoryl, sulfanyl, halo, cyano or carboxyl groups) by an appropriate thionating reagent. The resulting adducts, which is a S-protected 3-thio-2-isoxazoline, may be treated with base to remove the protecting group, to reveal a thiol or thiolate which may subsequently react with the arylmethyl bromide to form the Pyroxasulfone or Fenoxasulfone immediate precursor.
     
Ar = aryl, Y = protecting group and X = leaving group
Patent EP-4184960-A2 (EP)
Inventor: YANG YANMEI
IPC: H04W4/06
Filed: 2018-09-27
Abstract: This application discloses a communications system, a communication method, and an apparatus thereof. The communications system provided in this application achieves separation of a multicast service control function from a multicast transmission management function. The communications system includes a multicast session management network element, an access and mobility management network element and a user plane function network element. The multicast session management network element sends a first multicast session request to the access and mobility management network element, where the first multicast session request carries a multicast session context, and the first multicast session request is used to request to establish a multicast session based on the multicast session context; and sends a second multicast session request to the user plane function network element, where the second multicast session request carries user plane forwarding-related information used to indicate a user plane forwarding rule of the multicast session. The access and mobility management network element receives the first multicast session request, and sends the first multicast session request to an access network node. The user plane function network element receives the second multicast session request, and sets, based on the user plane forwarding-related information, the user plane forwarding rule of the multicast session.
Patent EP-4280501-A2 (EP)
Inventor: PARK HAEWOOK
IPC: H04L1/18
Filed: 2022-01-17
Abstract: Disclosed are a method for a terminal to transmit a feedback signal and a device for same in a wireless communication system according to various embodiments. The method comprises the steps of: receiving a first signal for scheduling a physical downlink shared channel (PDSCH); and determining whether to transmit the feedback signal related to a first signal, wherein the feedback signal is transmitted on the basis that the first signal includes control information for the activation or release of a semi-persistent scheduling (SPS) PDSCH, regardless of whether a hybrid physical downlink shared channel (HARQ) process for the PDSCH is disabled.
Patent EP-4253381-A2 (EP)
Title: Solid forms of (r)-1-(2,2-difluorobenzo[d][1,3]d ioxol-5-yl)-n-(1-(2,3-dihydroxyp ropyl)-6-fluoro-2-(1-hydroxy- 2-methylpropan-2-yl)-1h-indol- 5-yl) cyclopropanecarboxamide
Inventor: KESHAVARZ-SHOKRI ALI
IPC: C07D405/12
Filed: 2011-03-25
Abstract: The present invention relates to solid forms of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1) in substantially crystalline form (Form A) or amorphous form, pharmaceutical compositions thereof, and methods of treatment therewith.
Patent EP-4239236-A2 (EP)
Inventor: BEAGEN JOSEPH
IPC: F16L15/08
Filed: 2018-07-05
Abstract: Provided herein is a fire protection sprinkler system including a hanging connector joining together a plurality of flexible conduits. In one approach a sprinkler assembly includes a sprinkler body coupled to a first flexible conduit, and a hanging connector coupled to the first flexible conduit and to a second flexible conduit, wherein the hanging connector includes a hanging member extending outwardly from the hanging connector. The sprinkler assembly further includes a metallic connector extending between the hanging member and a support structure.
Patent EP-4252676-A2 (EP)
Title: Retractors
Inventor: BUTTERFIELD FORBES
IPC: A61B17/02
Filed: 2018-11-05
Abstract: The invention relates to a retractor 10. The retractor 10 comprises an elongate support member 14 having a screw thread 34 along at least part of its length and a first arm 16 having a first anatomy engaging member 42 depending therefrom. The retractor also comprises a second arm 18 having a second anatomy engaging member 42 depending therefrom and a threaded portion which cooperates with the screw thread to move the second arm along the support member. The retractor 10 also comprises a driver 24 operable to move the second arm 18 along the support member 14 by cooperation of the threaded portion and the screw thread 34 whereby separation between the first and second arms 16, 18 changes. The retractor 10 further comprises a bridging part 20 attached towards a first end thereof to the first arm 16 and attached towards a second, opposite end thereof to the second arm 18, the bridging part having a third anatomy engaging member 42 depending therefrom.
Patent EP-4246503-A2 (EP)
Title: Electronic device having display
Inventor: JUNG SONGHEE
IPC: G09G3/3208
Filed: 2017-03-24
Abstract: Disclosed in the present invention is a device comprising: a housing including a first surface facing a first direction and a second surface facing a second direction; a transparent cover formed on at least a portion of the first surface of the housing; a display disposed between the transparent cover and the second surface; a sensor disposed between the display and the second surface; and a control circuit, electrically connected to the sensor, for controlling the sensor, wherein the display can comprise: a first region including a plurality of pixels capable of displaying color; and a second region aligned on at least a portion of the sensor such that light acquired from the outside of the electronic device passes through the sensor. The present invention can have various examples.
Patent EP-0002673-A2 (EP)
Inventor: MCDANIEL MAX PAUL
IPC: C08F4/60
Filed: 1978-12-01
Abstract: High melt flow olefin polymers suitable for such applications as injection molding, and the like requiring a narrow molecular weight distribution are produced using a catalyst made by reducing and reoxidizing a chromium catalyst on either a titaniumsilica cogel or a self- reduced silica-containing composition. In the first embodiment. a cogel formed by coprecipitating silica and titania. and containing a chromium compound, is treated in a non-oxidizing atmosphere, such as CO, hydrogen, N 2  or a material decomposable to these materials, and thereafter reoxidized. In the second embodiment, a titanium-free chromium-containing catalyst is first heated in air or the like to dry the catalyst and oxidize the chromium after which it is heated in an inert atmosphere wherein the composition is self-reduced to give chromium in a lower valence state. The resulting selfreduced composition is then heated in a reducing ambient and then reoxidized as in the first embodiment.
Patent EP-0002734-A2 (EP)
Inventor: OEDIGER HERMANN DR
IPC: C07D317/60
Filed: 1978-12-14
Abstract: Verfahren zur Herstellung von Piperonylidencrotonsäureamiden der Formel <IMAGE> gemäß dem Piperonal mit Crotonsäureamiden der Formel <IMAGE> in Gegenwart von Hydroxiden der Formel A<+> OH<-> in der A<+> für eine quartäre Ammonium- oder Phosphoniumgruppe oder einen Alkalikomplex mit neutralen organischen Komplexliganden steht und unter den Reaktionsbedingungen inerten, polaren, aprotischen oder polaren, sterisch gehinderten, protischen, organischen Lösungsmitteln umgesetzt wird.
Patent EP-0029496-A2 (EP)
Inventor: PIEPENBREIER ERNST
IPC: B61C9/46
Filed: 1980-10-03
Abstract: A gear clutch comprises an annular clutch casing with a plurality of internal teeth and a clutch hub having a plurality of external teeth meshed with the internal teeth. The clutch is coaxial with the clutch casing and the external teeth have a load bearing part and a root. The clutch hub has an annular axially extending groove extending into the root from one side of the external teeth and ending below the external teeth and an annular radially extending groove on an opposite side of the external teeth and defining with the axially extending groove a cylindrical annular break section of a size smaller than that of the load bearing part, whereby the break section breaks before the load bearing part breaks when the gear clutch is overloaded.
Patent EP-0032588-A2 (EP)
Inventor: KANUMA AKIRA C O PROF EDWARD J
IPC: G05F3/20
Filed: 1980-12-23
Abstract: Disclosed is a substrate bias generator circuit which comprises an oscillator circuit (10), a driving circuit (20) producing a rectangular-wave signal in accordance with an oscillation output signal from the oscillator circuit (10), and a charge pump circuit (30) pumping electric charges into a substrate in accordance with the rectangular-wave output signal from the driving circuit (20). The oscillator circuit (10) is a voltage-controlled oscillator circuit whose oscillation frequency is controlled in accordance with a substrate bias voltage from the charge pump circuit (30).
Patent EP-0031744-A2 (EP)
Title: Dispositif et procédé pour la détermination de caractéristiques d'écoulement d'un fluide
Inventor: HULIN JEAN-PIERRE
IPC: G01P5/14
Filed: 1980-12-09
Abstract: L'invention concerne un dispositif pour déterminer la vitesse d'écoulement d'un fluide dans une conduite sensiblement verticale, comprenant deux capteurs sensibles à la même grandeur physique et espacés dans la direction de l'écoulement, la vitesse étant déterminée par corrélation entre les signaux de détection issus des capteurs, lesdits capteurs sont des capteurs de pression différentielle comprenant chacun deux prises de pression espacées dans la direction de l'écoulement, au moins deux prises appartenant à des capteurs différents étant alignées dans cette direction. Application à la mesure du débit dans un puits producteur de pétrole.
Patent EP-0036183-A2 (EP)
Inventor: DOKOUPIL JIRI DIPL ING
IPC: C14B1/58
Filed: 1981-03-12
Abstract: An apparatus and process for expanding the area and for drying of leather pieces, felts and other similar flat materials. On both sides of the leather elastic foils impervious to air are disposed, a vacuum is connected to the space between the two foils and then forces are applied for enlarging the area of the foils, where the forces are predominantly disposed in the plane of the foils. Thermal energy can be fed to the flat material. The forces can be intermittently applied and they can be provided preferably by hydraulic or pneumatic means.
Patent EP-0046480-A2 (EP)
Inventor: QUIJADA ALONSO VEGA
IPC: H01H9/26
Filed: 1981-04-13
Abstract: 1. Locking device for push buttons (9, 18) of electrical switching devices, in which on the inside of the casing of the switching device, a sliding member (1) under the force of a spring (4) is guided to move longitudinally, which cooperates with the push buttons (9, 18) whereby in one position of the sliding member (1), one push button (9) can be locked in the operating position and in all positions of the sliding member another push button (18) cannot be locked, characterised in that the push button (9) which can be locked comprises on the rear side a bolt (6) and a compression spring (10), that behind the end of the bolt (6) lying at a distance from the push button (9) which can be locked is a member (7) enlarged with respect to the other bolt part (8), that the sliding member (1) is constructed as a fork (5) at its end located behind the bolt (6), which fork has dimensions such that in the inoperative position of the push button (9) which can be locked, the ends of the fork bear externally on the enlarged member (7) and in the operative position of the push button (9) which can be locked engage in a locking manner around the other part of the bolt (8), that the sliding member (1) comprises groove-like stop locations (22, 23) for the selective engagement of a stationary tooth (25) connected to the casing cover (12), that one stop location (23) is adapted to the tooth (25) and arranged so that the sliding member can be held by the tooth (25) in such a position that the push button (9) which can be locked is unlockable, that the other stop location (22) has dimensions corresponding to the sliding movement of the sliding member (1) and in this stop location the tooth (25) limits the sliding movement and that the push button (18) which cannot be locked is constructed and cooperates with the sliding member (1) so that by actuating it locking of the push button (9) which can be locked is cancelled out.
Patent EP-0043943-A2 (EP)
Inventor: ABBAS SHAKIR AHMED
IPC: H01L21/3205
Filed: 1981-06-23
Abstract: method for forming field effect transistor integrated circuits having a pattern of narrow dimensioned dielectric regions and more particularly a self-aligned metal process is described which achieves self-aligned metal to silicon contacts and submicron contact-to-contact and metal-to-metal spacing for field effect transistor integrated circuits. The insulation between the contacts and the metal is a pattern of dielectric material having a thickness dimension in the order of a micron or less. The metal and dielectric structure is substantially planar. The method for forming integrated circuits with this structure involves providing a silicon body (10) and then forming a first insulating layer (14) on a major surface of the silicon body. A layer of polycrystalline silicon (16) is formed thereover. Openings are made in the polycrystalline silicon layer by reactive ion etching which results in the structure having substantially horizontal surfaces (20) and substantially vertical surfaces (21). The openings can be in either the areas designated to be the gate regions or a PN junction region of the field effect transistors in the integrated circuit. A second insulating layer (22) is then formed on both the substantially horizontal surfaces (20) and substantially vertical surfaces (21). Reactive ion etching of this second insulating layer substantially removes the horizontal layers and provides a narrow dimensioned dielectric pattern of regions (22) on the major surface of the silicon body (10). The gate dielectric is either formed hereat or PN junctions are fabricated by diffusion or ion implantation techniques. The remaining polycrystalline silicon layer (16) is then removed by etching to leave the narrow dimensioned regions (22) on the major surface of the silicon body (10). A conductive layer is blanket deposited over the narrow dimensioned regions and areas in between to make contact to source;drain PN regions and form the gate electrodes. A blanker layer of a plastic material over the conductive layer is used to planarize the surface. Reactive ion etching the plastic material and the conductive layer is continued until the tops of the narrow dimensioned regions are reached leaving the structure of patterns of metal or polycrystalline silicon filling the regions between the pattern of dielectric material having having a thickness dimension in the order of a micron or less. The gate, source and drain electrodes are thusly formed.
Patent EP-0045493-A2 (EP)
Inventor: LINDENTHAL MARGARET
IPC: A61K8/73
Filed: 1981-07-30
Abstract: A composition which forms a gel when mixed with water and is suitable for use as a face mask, the composition being comprised of a water soluble alginate material, a water soluble, bivalent metal salt reactor, a phosphate retarder, a suitable extender and an anionic surfactant.
Patent EP-0051160-A2 (EP)
Inventor: JACKLIN ROGER LAYTON
IPC: F16C35/077
Filed: 1981-10-07
Abstract: Ein spiralverzahntes Ritzel (22) sowie ein mit ihm kämmendes Spiralzahnkegelrad (24) sind in einem üblichen Gehäuse (10, 16) gelagert. Das erfindungsgemäß zu lösende Problem ergibt sich aus der auf die Ritzelwelle (20) ausgeübten Längsschubkraft, die im Betrieb aus dem genannten Zahnradeingriff resultiert. Zur Lösung dieses Problems ist erfindungsgemäß eine Federvorspannung (48) vorgesehen, die das vor dem Ritzel (22) liegende Lager (28) für axiale und radiale Belastung von der genannten Längsschubkraft entlastet und so die Verwendung leichterer und damit preiswerterer Lager gestattet. Erfindungsgemäß ist ferner ein Nadellager (52) vorgesehen, dessen radial ausgerichteten Nadeln zwischen dem inneren Laufring (30) des Hauptlagers (28) und der genannten Federvorspannung (48) liegen.
Patent EP-0054792-A2 (EP)
Inventor: ENGLER GUSTAV ING GRAD
IPC: F02B29/04
Filed: 1981-12-04
Abstract: The invention relates to a common cooling circuit for the combustion engine and the charge, the cooling of the combustion engine being carried out at a higher temperature level via a main cooler (2) and the cooling of the charge being carried out at a lower temperature level via an auxiliary cooler (4). The overall quantity of coolant emerging from the combustion engine (1) is initially fed via the main cooler (2) and is then divided into two partial flows (16, 17) of which the one partial flow (16) is directed via the auxiliary cooler (4) and the charge cooler (5) and is combined with the other partial flow (17) again before entering into the combustion engine (1). In this way, the complete quantity of coolant flows through the main cooler (2) and the combustion engine (1), while only a partial flow (16) flows through the auxiliary cooler (4). <IMAGE>
Patent EP-0052449-A2 (EP)
Inventor: BARABAS EUGENE S
IPC: C08F236/10
Filed: 1981-10-28
Abstract: The random emulsion polymerisation product of a mixture of monomers in the presence of a chain transfer agent, in which the monomers comprise styrene, butadiene, a-methylstyrene and a copolymerisable carboxylic acid, has adhesive properties. It can be used as a single-component pressure-sensitive adhesive, e.g. as a coating on a suitable backing material.
Patent EP-0071895-A2 (EP)
Inventor: KUPF LUBOMIR
IPC: B28B7/34
Filed: 1982-07-29
Abstract: 1. Plastic mould for moulding concrete test cubes, which has been prepared of structurally foamed polyolefin of 0,5 to 0,85 g/cm**3 density by extrusion as a sandwich construction having peripheral walls (1) with ribs (5) and a bottom (2), which has been strengthened by a peripheral flange (3) having at least three protrusions (8) and an inner rim (4) standing by 0.2 to 2.0 mm higher than the outer rim thereof, and which has been provided in the center of the bottom (2) with a conical hole (6) diverging in the direction toward the hollow (7) of the mould.
Patent EP-0080565-A2 (EP)
Inventor: STASKE REINER
IPC: E05F15/50
Filed: 1982-09-08
Abstract: The working piston is designed in the shape of a pot and forms a first valve with a recess arranged in the region of a first end wall of the working cylinder, and a second valve with a projection arranged in the region of the second end wall of the working cylinder. The recess provided in the first end wall is adapted to the external diameter of the pot-shaped working piston. The internal diameter of the pot-shaped working piston is adapted to the external diameter of the projection arranged on the second end wall. As each of the two chambers of the working cylinder are vented via a throttle boring and additionally via the associated valve, the pressure reduction in the chamber to be vented takes place when the working cylinder reaches a predetermined position, and the resulting closing of the valve continues only in a throttled manner via the throttle boring, so that the working cylinder travels in a slowed manner into its end position.