baber/WOPTO huggingface dataset:
Patent CO-6260068-A2 (CO)
Title: Formas polimorficas de (s)-2-((4-benzofuranil)carbonilaminometil)-1-((4-(2-metil-5-(4-fluorofenil)tiazolil)carbonil)piperidina
Inventor: KINDON LEANDA JANE
IPC: A61K31/427
Filed: 2010-03-15
Abstract: Nuevas formas polimórficas de (S)-2-((4-benzofuranil)carbonilaminometil)-1-((4-(2-metil-5-(4-fluorofenil))tiazolil)carbonil)piperidina, métodos para su preparación y uso en medicina. 1.- Una forma polimórfica de (S)-2-((4-benzofuranil)carbonilaminometil)-1-((4-(2-metil-5-(4-fluorofenil))tiazolil)carbonil)piperidina (Forma 1) caracterizada por que: i) proporciona un difractograma de difracción de rayos X de polvo (XRPD) que comprende los siguientes picos: yii) tiene un comienzo de fusión en el intervalo de 163-173°C, tal como se midió mediante análisis por DSC. 2.- Un polimorfo de acuerdo con la reivindicación 1, caracterizado además por que proporciona un patrón de difracción de rayos X de polvo (XRPD) sustancialmente de acuerdo con la Figura 7.
Patent CO-6351727-A2 (CO)
Title: Derivados de piridazina como inhibidores de smo
Inventor: HE FENG
IPC: A61K31/501
Filed: 2011-01-19
Abstract: La presente invención se refiere a Derivados de Piridazina, en útiles en el diagnóstico y el tratamiento de patologías relacionadas con la trayectoria de Hedgehog, incluyendo, pero no imitándose a, formación de tumor, cáncer, neoplasia, y trastornos hiperproliferativos no malignos. La presente invención incluye compuestos novedosos, composiciones novedosas, métodos para su uso, y métodos para su fabricación, en donde estos compuestos son en general farmacológicamente útiles como agentes en terapias cuyo mecanismo de acción involucra métodos para inhibir la tumorigénesis, el crecimiento tumoral y la sobrevivencia de tumores, utilizando agentes que inhiben la trayectoria de señalización de Hedgehog y Smo.
Patent CO-6501177-A2 (CO)
Title: Composición nutricional que comprende curcuminoides y métodos para fabricarla
Inventor: JOHNS PAUL W
IPC: A23L5/40
Filed: 2011-09-29
Abstract: Composiciones nutricionales y métodos pata preparar las composiciones, que comprende grasa, proteína e hidrato de carbono, que incluye una combinación de curcumina, demetoxicurcumina, y bisdemetoxicurcumina, en donde la combinación se solubiliza en un aceite polar que tiene un valor de HLB de entre aproximadamente 0,7 y aproximadamente 14 en donde la proporción en peso de la bisdemetoxicurcumina a la curcumina es de entre aproximadamente 1:1 y aproximadamente 1:7 y la proporción en peso de la bisdemetoxicurcurnina a la demetoxicurcumina es de entre aproximadamente 1:1 y aproximadamente 1:2.5. La composición provee una proporción seleccionada de curcuminoides que tienen mejores actividad biológica, biodisponibilidad, y menor impacto de color.
Patent CO-7020861-A2 (CO)
Title: Métodos para la obtencion de plantas de palma de aceite de alto rendimiento
Inventor: OOI TONY ENG KEONG
IPC: A01H6/00
Filed: 2014-04-02
Abstract: Se proporcionan métodos para obtener plantas de palma de aceite de alto rendimiento, que comprende determinar el nivel de una proteína en el tejido del mesocarpio de una fruta de una planta madre de palma de aceite, determinar si hay una diferencia entre el nivel de la proteína en el tejido del mesocarpio de la fruta de la planta madre de la palma de aceite y el nivel de la proteína en el tejido del mesocarpio de una fruta de una planta de referencia de la palma de aceite, y seleccionar la progenie de la planta madre de palma de aceite con base en la diferencia para obtener la planta de palma de aceite de alto rendimiento. También se proporcionan métodos para predecir el rendimiento en aceite de una planta de prueba de palma de aceite y kits para obtener una planta de palma de aceite de alto rendimiento.
Patent EP-1110632-A2 (EP)
Inventor: KNAAPI HEIKKI
IPC: B21B13/00
Filed: 2000-03-03
Abstract: A roller head for a planetary rolling arrangement,
said roller head (1) comprising a housing (8), inside
which housing there is rotatably arranged a hollow
outer axis (5) and means (2, 3, 4), for rotating said
outer axis, as well as inside said outer axis, in a
manner that transmits the rotary motion thereof, a
center axis (6), which is movable in the axial
direction and can be locked in the axial direction,
said center axis (6) being provided with a roller (7).
The roller head is characterized by an adjusting axis
(16) which is rotatably arranged at the end of the
outer axis (5) that is located on the opposite side
with respect to the roller (7) and is essentially locked
in the axial direction, said adjusting axis (16)
comprising a counterpart (17) for the threaded
section (15) provided in the center axis (6), and said
adjusting axis also including a locking member (18),
which in the locking position forms a friction coupling
at least between the adjusting axis (16) and the
outer axis (5).
Patent EP-1044772-A2 (EP)
Inventor: KALMBACH KURT
IPC: B23C3/12
Filed: 2000-03-28
Abstract: The appliance for machining the edges of a plate-shaped work-piece (12) comprises a first cutting tool (1) which has a basic tool diameter. The cutting tool has a sensor (10) for guiding the appliance over the work-piece. A further cutting tool (3) has the s basic diameter as the first cutting tool but a different cutting action. The further cutting tool is movable between a non-opera to an operating position. The first, and at least one other, cutting tool are movably positioned on the same pin (6). by means o pneumatic or hydraulic adjustment (16) and coupling-fork (22).
Patent EP-1059129-A2 (EP)
Inventor: BOEHM KONRAD
IPC: B21D15/03
Filed: 2000-05-16
Abstract: The twin-chamber pressure package, where one chamber holds the filled contents and the other chamber has the pressurized propellant, has a sealed beaded edge between the inner and outer containers (1,2). The inner container (2) has nominal distortion zones (25) to give a targeted collapse and prevent the formation of sharp edges or folds. The nominal distortion zones (25) are formed by the insertion of a tool spindle (11) into the inner container (2) to develop a pressure difference between its interior (7) and the propellant zone (8) and take up the contour shape of the tool spindle (11) by pressure or suction.
Patent EP-1058370-A2 (EP)
Inventor: REMUS HANS-JUERGEN DR
IPC: H02K1/27
Filed: 2000-06-02
Abstract: A yoke (10-1) has a slot on or across a generator hollow shaft (10-3) and ventilation holes for feeding air in and out of an annular gap (10-2) in a permanent magnet (P1-P4) arrangement. During the operation of the generator with a multi-pole rotor (10) and a coil unit (20) with four windings (20-1,20-2,20-3,20-4) corresponding to the number of poles, coil windings are coupled in any combination behind each other or parallel.
Patent EP-1056132-A2 (EP)
Inventor: KITAHARA TAKASHI
IPC: H05K7/20
Filed: 1993-08-06
Abstract: A heat-generating element cooling device comprises a heat sink disposed on a top surface of a heat-generating element and having a plurality of heat-radiating fins and a cooling fan unit disposed above the heat sink and having a motor portion rotating at its center, wherein said fan unit has at least one auxiliary blade provided at a bottom surface of the motor portion and extending in toward the thickness direction of said heat sink.
Patent EP-1096355-A2 (EP)
Inventor: WOHLLEBE THOMAS DIPL-ING
IPC: B60K23/02
Filed: 2000-09-12
Abstract: The operating unit e.g. a hydraulic master cylinder (2), Bowden cable or gas (air) brake system, is also held on the slide (6). Relative position of pedal and operating unit is unaltered by movement of the slide, simplifying construction. The operating unit is no longer attached to the bulkhead; should the latter intrude in a collision, additional swing of the pedal towards the driver cannot occur.
Patent EP-1088616-A2 (EP)
Inventor: KSCHIER UWE
IPC: B23Q1/52
Filed: 2000-09-25
Abstract: The clamping device for fixing the rotary or pivoting device (2) in the chosen angle position comprises a clamp part (7) on top of the support (1) for the device, and a press part (12) which can be moved relative to the clamp part. This clamp part has laterally resilient clamping sections (8, 9) for engaging with a ring groove (11) in the device. The press part is used to press the clamping sections against at least one side wall of the groove.
Patent EP-1089265-A2 (EP)
Inventor: KAGAYA HIROYUKI
IPC: G11B7/08
Filed: 2000-09-27
Abstract: There is provided an optical device in which a neutral
position setting for each of the adjustment screws can be
carried out easily and accurately while its workability is being
superior and its cost is not being increased. There are
arranged on a chassis formed by a sheet metal, a spindle motor
on which a turntable for use in mounting an optical disk D is
attached, an optical pickup, guide shafts for guiding the
optical pickup in a radial direction of the optical disk D, the
first and second supporting members and the third and fourth
supporting members for supporting both ends of the guide shafts,
and adjustment screws for moving a height position of one end
of the guide shaft and the height positions of both ends of the
guide shaft, and the chassis is provided with resin fixing
members having fixing surfaces to attach and fix the spindle
motor and resin reference members having reference planes
within the same plane.
Patent EP-1109428-A2 (EP)
Title: Thermomechanisch kompensierte Leiterplatte
Inventor: KHILLA ABDEL-MESSIAH
IPC: H05K1/02
Filed: 2000-10-11
Abstract: Eine Leiterplatte für die Montage von wenigstens zwei Gruppen von Schaltungsbausteinen (5,6,7), die sich in ihren thermischen Ausdehnungskoeffizienten unterscheiden, ist an einem oder mehreren Orten mit einer steifen Einlage (2) ausgestattet, deren thermischer Ausdehnungskoeffizient sich von dem des Materials der Leiterplatte (1) unterscheidet, so daß der Ausdehnungskoeffizient der Leiterplatte an diesem Ort/diesen Orten sich vom Ausdehnungskoeffizienten der Leiterplatte (1) an Orten, die die Einlage nicht aufweisen, unterscheidet. <IMAGE>
Patent EP-1130103-A2 (EP)
Title: Neue Nukleinsäure aus Tetrahymena kodierend für eine Trieterpenoid-Cyclase, ihre Herstellung und Verwendung
Inventor: RUESING MATTHIAS DR
IPC: C12N9/90
Filed: 2000-11-27
Abstract: Die vorliegende Erfindung betrifft Nukleinsäuren aus Tetrahymena die für eine ciliatenspezifische Triterpenoid-Cyclase kodieren. Die erfindungsgemäßen Nukleotidsequenzen und die daraus abgeleitete Polypeptidsequenz zeigen dabei eine überraschend geringe Sequenzidentität zu bekannten Isoprenoid-Cyclasen. Die Erfindung betrifft ferner die Verwendung der Nukleinsäuren für eine kontrollierte Expression in einem Wirt sowie deren gezielte Ausschaltung (Knock-out) oder Reprimierung. Durch die dadurch bewirkte Kontrolle der Expression der Triterpenoid-Cyclase ist es möglich, den Gehalt an mehrfach ungesättigten Fettsäuren im Wirt zu modifizieren und anzureichern. <IMAGE>
Patent EP-1107374-A2 (EP)
Inventor: ENGBRING JUERGEN DR
IPC: H01R12/71
Filed: 2000-11-30
Abstract: Two bonding areas (8) are three-dimensionally structured to complement each other. A mask (12) has recesses (14) for bonding elements (10) on two printed circuit boards (2,4). Using a strip conductor pattern for positioning without relying on a bonding casing means that positioning accuracy is not affected by tolerances between the strip conductor pattern and the bonding casing.
Patent EP-1134153-A2 (EP)
Inventor: KARIYAMA OSAMU
IPC: B62L1/00
Filed: 2000-11-30
Abstract: A bicycle brake device (12; 112) is disclosed having a first brake arm body (34a; 134a), a
first lid (38a; 138a), a second brake arm body (34b; 134b) and a second lid (38b; 138b).
The first brake arm body (34a; 134a) has a first attachment opening (80a) and a first fastener
recess (82a) located adjacent said first attachment opening (80a). The second brake arm
body (34b; 134b) has a second attachment opening (80b) and a second fastener recess (82b)
located adjacent said second attachment opening (80b). The second brake arm body (34b;
134b) is adapted to be operatively coupled to the first brake arm body (34a; 134a) to move
the first (34a; 134a) and second (34b; 134b) brake arm bodies between a release position
and a braking position. The first lid (38a; 138a) is detachably coupled to the first brake arm
body (34a; 134a) to overlie the first fastener recess (82a). The second lid (38b; 138b) is
detachably coupled to the second brake arm body (34b; 134b) to overlie the second fastener
recess (82b). First (40a; 140a) and second (40b; 140b) covers can also be provided to overlie
the attachment openings (80a, 80b) of the brake arm bodies (34a, 34b; 134a, 134b). The
lids (38a, 38b; 138a, 138b) can be attached to the brake arm bodies (34a, 34b; 134a, 134b)
in a variety of ways. In one example, the lids (38a, 38b; 138a, 138b) are completely detachable
from the brake arm bodies (34a, 34b; 134a, 134b). In another example, the lids (38a,
38b; 138a, 138b) are partially detachable from the brake arm bodies (34a, 34b; 134a, 134b).
Patent EP-1113200-A2 (EP)
Inventor: UDAGAWA TSUNEKAZU
IPC: F02F1/00
Filed: 2000-12-22
Abstract: A sealing mechanism for an internal combustion engine is
formed of a cylinder head (3, 3A, 3B) having a liquid hole (34,
34'), a cylinder block (2, 2A, 2B) having a cylinder bore (22) and
a liquid hole (24, 25), a first groove (23, 33, 23A, 23B) formed at
least in one of the cylinder head and the cylinder block around the
cylinder bore (22), a second groove (25, 25A, 25B, 35) formed at
least in one of the cylinder head and the cylinder block around the
liquid hole, and a metal gasket (4, 4A, 4B) situated between the
cylinder head and the cylinder block to seal therebetween. The
metal gasket has a first bead (43a, 43b, 43A, 43B) located in the
first groove and a second bead (45a, 45b, 45A, 45B) located in the
second groove. The shapes of the first and second beads (43a, 43b,
43A, 43B; 45a, 45b, 45A, 45B) and the shapes of the first and
second grooves (23, 33, 23A, 23B; 25, 25A, 25B, 35) are selected to
form a first sealing pressure formed between the first bead and the
first groove to be different from a second sealing pressure formed
between the second bead and the second groove.
Patent EP-1022552-A2 (EP)
Inventor: PORTER KEVIN J
IPC: G01M3/32
Filed: 2000-01-05
Abstract: A method for the automated detection of leaks between the high and low-pressure sides
of a refrigeration system is provided. A large pressure difference is created between the high
pressure side and low-pressure side. By measuring and comparing system pressures at different
times, the operational condition of valves which connect the high pressure side to the low-pressure
side is accurately determined. By accurately determining that these valves are operating
correctly, and in particular that no leaks exist in the valves, reports of false failures are prevented,
while the reduction in the refrigeration system's capacity to heat or cool is prevented.
Patent EP-1106821-A2 (EP)
Inventor: ROBINSON BARRY S
IPC: F02M69/54
Filed: 2000-11-28
Abstract: A fuel system that comprises a tank, a pump, a flow-through pressure
regulator, and piping connecting these components and an internal combustion
engine. The flow-through pressure regulator can maintain a substantially constant
noise output from low fuel flow rates to high fuel flow rates. Further, the pressure
of fuel in the regulator at a maximum fuel flow rate can be made substantially equal
to or less than the pressure of fuel in the regulator at a minimum fuel flow rate.
Patent EP-1120602-A2 (EP)
Inventor: GUZZINI MARCO
IPC: F21V3/00
Filed: 2000-12-18
Abstract: A device (10) for supporting shielding elements (19)
for lighting apparatuses (22) comprises a base (11) and
a pair of elastic elements (12, 13) set opposite to one
another, where the base (11) can be inserted so that it
rests on the lamp-holder rim (14) and where the elastic
elements (12, 13) set opposite to one another consist
of a pair of metal wires. Each of the wires is shaped
in such a way as to enable, via co-operation with the
wire set opposite to it, clamping and support of a
shielding element (19) set in front of the light source
(20).
Patent EP-1020665-A2 (EP)
Inventor: IIJIMA MAKOTO
IPC: F16D48/02
Filed: 2000-01-10
Abstract: A control apparatus for an automatic transmission (13) of a vehicle having a
forward friction element (42) for engaging or disengaging a turbine shaft (7) with the
automatic transmission in a forward funning direction and a lock-up clutch (11) for
directly transmitting a rotation of an engine (1) to the turbine shaft (7), comprises an
abrupt deceleration control means for disengaging the forward engagement element
(42) and the lock-up clutch (11) when an abrupt deceleration of the vehicle is
detected, and a restoring means for canceling the abrupt deceleration control means
and for restoring the forward friction element (42) to an engagement state when an
accelerator pedal is depressed for acceleration.
Patent EP-1089358-A2 (EP)
Inventor: TAKEUCHI YUKIHISA
IPC: H01L41/43
Filed: 2000-09-29
Abstract: A piezoelectric/electrostrictive device (10A) comprises
a pair of mutually opposing thin plate sections (16a, 16b),
a movable section (20), and a fixation section (22) for
supporting the thin plate sections (16a, 16b) and the
movable section (20); piezoelectric/electrostrictive
elements (24a, 24b) arranged on a pair of thin plate
sections (16a, 16b) respectively; and a hole (12) formed by
both inner walls of the pair of thin plate sections (16a,
16b), an inner wall (20a) of the movable section (20), and
an inner wall (22a) of the fixation section (22), wherein a
through-hole (36) having a rectangular cross section is
formed over a range from the forward end surface of the
movable section (20) to the hole (12) to realize a light
weight of the movable section (20).
Patent EP-1103229-A2 (EP)
Inventor: EHNHOLM GOSTA JAKOB
IPC: A61B10/00
Filed: 2000-11-27
Abstract: An interface system is provided for planning a surgical procedure for inserting an object
into a patient along a surgical planning trajectory from an entry point (150) on the patient
to a target point (152) within the patient. Using an imaging device, a first scan of the
patient is performed to generate a first image volume data set of a first area of the patient.
A first sectional image (130) of the patient is displayed on a human-readable display device
associated with the imaging device. The first sectional image is based on the first image
volume data set. Using an operator interface device, a second planning image of the patient
is defined by placing a plurality of graphical point symbols (136) in the first sectional image
of the patient displayed on the display device. The plurality of graphical point symbols
define a second area of the patient to be subject of display as a second sectional image of
the patient. The second sectional image of the patient is derived either directly from the
first image volume data set, indirectly from the first image volume data set by interpolation,
or by performing a second scan of the patient with the imaging device.
Patent EP-1111076-A2 (EP)
Inventor: BRAMLEY ALAN
IPC: F27D99/00
Filed: 2000-12-18
Abstract: A dross pot and sow mould combination for use with a dross
press, the combination being suitable for melting furnaces with low sills.
The sow mould is connected to the dross pot by a variable length
connection which allows the height of the combination to be low when the
combination is positioned by the furnace, but larger when the combination
is positioned in the dross press.
Patent EP-1076412-A2 (EP)
Inventor: SUGIMOTO KATSUYOSHI
IPC: H03F1/32
Filed: 2000-08-09
Abstract: A first vector modulator is inserted in the input
route of an amplifier to vary the input signal of the
amplifier. A second vector amplifier is inserted in the
second signal route to vary the input signal of the second
signal route. A controller controls the first vector
modulator to minimize the distortion of the amplifier and
controls the second modulator to equalize a change in
input signal of the amplifier due to the control operation
to a change in input signal of the second signal route.
Patent EP-1140162-A2 (EP)
Inventor: WATKINS DAVID I
IPC: A61K39/385
Filed: 2000-01-06
Abstract: A method for inducing an epitope-specific cytotoxic lymphocyte response in primates is disclosed. The method involves delivering a DNA-based vaccine that encodes an MHC class I epitope and a polyepitope and an MHC class I epitope and the hepatitis B core antigen into the primate, followed by delivering a modified virus vaccine that encodes an MHC class I epitope and a polyepitope into the primate.
Patent EP-1165106-A2 (EP)
Inventor: PHILLIPS NIGEL C
IPC: A61K35/74
Filed: 2000-03-30
Abstract: A method for treating prostate cancer in an animal, wherein a composition comprising Mycobacterium phlei (M. phlei) DNA (M-DNA) and M-DNA preserved and complexed on M. phlei cell wall (MCC) is administered to the animal in need of such treatment in an amount effective to have an anti-neoplastic effect on cancer cells in the prostate of the animal.
Patent EP-1166336-A2 (EP)
Title: Anlage zur fertigung von halbleiterprodukten
Inventor: HEINEMANN BERNHARD
IPC: F24F7/06
Filed: 2000-03-24
Abstract: Die Erfindung betrifft eine Anlage zur Fertigung von Halbleiterprodukten, insbesondere von Wafern, mit einer Anordnung von Fertigungseinheiten (1) in wenigstens einem Reinraum (2) mit einem Luftversorgungssystem. Bei dem Luftversorgungssystem erfolgt die Luftzufuhr über den Boden (7) des Reinraums (2).
Patent EP-1194137-A2 (EP)
Title: Derives de naphtoquinone et leurs utilisations dans le traitement et l'eradication de la tuberculose
Inventor: MEYER JACOBUS JOHANNES MARION
IPC: A61K31/122
Filed: 2000-06-22
Abstract: L'invention concerne des dérivés de naphtoquinone, ou des sels pharmaceutiquement acceptables de ces dérivés, lesquels dérivés sont représentés par la formule (1): dans laquelle R représente un groupe OH, un méthyléther, un éthyléther ou un éther similaire; R1 représente un méthyle, éthyle ou un dérivé d'hydrocarbure aliphatique similaire; R2 et R3 représentent chacun indépendamment hydrogène ou un groupe choisi parmi: (A), (B) ou (C) où R5 représente un groupe OH, un méthyléther, un éthyléther ou un éther similaire et R6 représente un méthyle, un éthyle ou un dérivé d'hydrocarbure aliphatique similaire; R4 représente hydrogène ou un groupe choisi parmi: (D), (E) ou (F) où R7 représente un groupe OH, un méthyléther, un éthyléther ou un éther similaire et R8 représente un méthyle, un éthyle ou un dérivé d'hydrocarbure aliphatique similaire. Les dérivés selon l'invention sont utilisés dans le traitement et/ou l'éradication d'une tuberculose causée chez un patient par Mycobacterium tuberculosis.