baber/WOPTO huggingface dataset:
Patent CA-2492007-A1 (CA)
Title: Amplification of nucleic acid fragments using nicking agents
Inventor: VAN NESS JEFFREY
IPC: C12Q1/68
Filed: 2002-07-15
Abstract: The present invention relates to compounds, kits and methods for detecting a genetic variation in a target nucleic acid, detecting the presence, or the absence of a particular nucleic acid in a biological sample, preparing singl e- stranded nucleic acid probes, and detecting pre-mRNA differential splicing i n a target cDNA molecule or a cDNA population. It utilizes a nicking agent in the amplification of a single-stranded nucleic acid fragment that either contains a genetic variation of the target nucleic acid, has a unique sequen ce correlating to the particular nucleic acid, is complementary to a nucleic ac id of interest, or comprises an exon-exon junction. Detection and/or characterization of this short single-stranded nucleic acid fragment identifies the genetic variation of the target nucleic acid, indicates the presence of the particular nucleic acid in the sample, makes single-stranded nucleic acid probes for the nucleic acid of interest, or detecting the presence of the exon-exon junction in the target cDNA molecule or the cDNA probes.
Patent CA-2492311-A1 (CA)
Inventor: STEWART MATTHEW
IPC: C23C4/00
Filed: 2005-01-13
Abstract: A method (100) for fabricating and testing an article having a thermal-spray coating thereon. The method includes providing (102) a substrate article having a surface, thermally spraying (104) a coating material onto the surface of the substrate article, wherein a surface of contact between the coating material and the substrate article is a bondline, and nondestructively testing (106) the coated article. Nondestructively testing includes generating (108) an eddy current in the coated article, measuring (110) the eddy current in the coated article, and evaluating (112) a near- bondline region of the coated article located adjacent to the bondline using the measured eddy current.
Patent CA-2493458-A1 (CA)
Inventor: CHEN GUANGMING
IPC: A61K31/4166
Filed: 2003-07-23
Abstract: L'invention concerne des composés d'acide benzoïque à substitution uréido, des compositions renfermant ces composés et des procédés de traitement ou de prévention de maladies associées à des mutations de non-sens d'ARNm par administration de ces composés ou de ces compositions.
Patent CA-2493946-A1 (CA)
Inventor: HITOS SANCHEZ MIGUEL
IPC: B63B21/56
Filed: 2003-07-22
Abstract: The invention relates to an automatic system for taking up and handling a connecting towrope between a tugboat and a towed vessel. The inventive syste m comprises a fastening carriage which moves on guides around the deck of the tugboat. Once the towrope has been launched from the vessel to be towed, the aforementioned carriage moves along the guide until the built-in sensor detects the presence of the towrope at the upper part of the gunwale. The above-mentioned fastening carriage comprises a clamp and the tow cable or ro pe of the tugboat is fixed therein. According to the invention, when the system detects that the towrope has been inserted in the clamp, said clamp is close d and the carriage is released, the tugboat rope remaining connected to the towrope of the vessel. Once the aforementioned operation has been performed, the fastening carriage returns to the rest position thereof. The system operates automatically without the need for any human intervention on the de ck of the tugboat and said system is remote controlled from the bridge.
Patent CA-2494157-A1 (CA)
Title: Inclusion complexes of butylphthalide with cyclodextrin or its derivatives, a process for their preparation and the use thereof
Inventor: LIU WEN-JUAN
IPC: C07D307/88
Filed: 2002-08-21
Abstract: The present invention relates to the clathrates of butylphtualide, which is D,L-mixed or levorotatory, with cyclodextrin or its derivatives, a process f or their preparations and the use thereof. In the invention, the butylphthalide is included with cyclodextrin or its derivatives, prefered hydroxypropyl- .beta.-cyclodextin, in order to improve the water-solubility of butylphthalide, develop clinical solid or liquid formulation and so that the curing effect of butylphthalide can exhibit better. The clathrate, in which the mole ratio of butylphthalide and cyclodextin or derivatives thereof is 1 :1- 10, can be used in preparing transfusion, injection, injectable powder, oral ly liquid, syrup, tablets, granules,dispersible tablets and others.
Patent CA-2495103-A1 (CA)
Inventor: UENO RYUJI
IPC: A61K31/4745
Filed: 2003-08-08
Abstract: La présente invention concerne des compositions ophtalmiques et des traitements de symptômes d'allergies oculaires. Le principal principe actif de ces compositions et traitements est un composé de macrolide, tel que le tacrolimus, l'ascomycine et la rapamycine et leurs dérivés. L'invention concerne également des concentrations et posologies optimales.
Patent CA-2495979-A1 (CA)
Title: Turboreacteur a soufflante solidaire d'un arbre d'entrainement supporte par un premier et un deuxieme paliers
Inventor: LAPERGUE GUY
IPC: F01D25/16
Filed: 2005-02-02
Abstract: Le turboréacteur de l'invention comprend une structure fixe, un rotor de souftlante, solidaire d'un arbre d'entraîmement (5) supporté par un premier palier (6) et un deuxième palier (7), montés sur ladite structure fixe par l'intermédiaire d'une pièce support de palier (11, 19) le premier palier (6) étant monté sur la structure fixe du turboréacteur par un dispositif (13) permettant son découplage (13) par rapport à  la structure fixe, caractérisé par le fait que le deuxième palier (7) est monté sur la pièce support de palier (19) par une liaison formant rotule (23, 24) et que le turboréacteur comprend en outre des moyens autorisant des déplacements axiaux du deuxième palier (7) par rapport à la structure fixe du turboréacteur en cas de découplage du premier palier (6).   Ainsi, la fonction de centrage du deuxième palier (7) après découplage du premier palier (6) est assurée, sans introduction de contraintes excessives dans le palier (7).
Patent CA-2499301-A1 (CA)
Inventor: POUCHKAREV ALEXANDER S
IPC: F17C1/00
Filed: 2003-09-16
Abstract: La présente invention concerne un vaisseau (10) sous pression multicouche fabriqué à partir d'au moins une feuille à un pli de matière souple (100) possédant une ligne médiane longitudinale qui divise ce matériau en une partie intérieure (130) possédant une surface intérieure, une surface extérieure, un bord, une réserve de couture et une largeur et, une partie extérieure possédant une surface intérieure, une surface extérieure, un bord, une réserve de couture et une largeur. La largeur de la partie extérieure (120) est plus grande que la largeur de la partie intérieure (140). Une couture principale (250) lie la partie extérieure et la partie intérieure à la feuille de matière au niveau de la ligne médiane près du bord de la partie intérieure et de la partie extérieure. La feuille est enroulée en un enroulement sensiblement continu de 720 degrés de façon à former un corps de vaisseau généralement cylindrique possédant de multiples éventuels passages de fluide, selon le choix de l'utilisateur. La couture principale (250) est cachée.
Patent CA-2499705-A1 (CA)
Inventor: MATHIEU DAVE
IPC: B43K3/00
Filed: 2003-10-21
Abstract: An elastic member and a shaft body to which the elastic member is fixed are relatively rotatable, and means for keeping their positions after the relati ve rotation is provided. A grip structure is adjustable by relatively rotating the elastic member and the shaft body to different sizes of hands holding th e grip structure and to preferred shapes. The preferred shapes can be maintained. A further effect of the grip structure is that its appropriate hardness can be selected and maintained. These can be achieved with a relatively simple component structure.
Patent CA-2502395-A1 (CA)
Title: Measurement device for determining oxygen activity in metal or slag melts
Inventor: HABETS DANNY
IPC: G01N33/20
Filed: 2005-03-24
Abstract: A measurement device is provided for determining the oxygen activity in molt en metal or slag with a measurement head, which is arranged on one end of a carrier tube and on which an electrochemical measurement cell is arranged. The electrochemical measuremen t cell has a solid electrolyte tubule, which is closed on one side and which contains on its closed end a reference material and an electrode, which projects from the opposite end of the solid electrolyte tubule. The solid electrolyte tubule has on its outer surface a coating made from a mixture of zirconium silicate with a fluoride. The measurement head may also have a thermo-element, and th e device may be used to determine the concentration of silicon and/or carbon in the melt, based on the oxygen activity measurement.
Patent CA-2504880-A1 (CA)
Inventor: STAHLY G PATRICK
IPC: A61K31/519
Filed: 2001-08-02
Abstract: This invention relates to novel crystalline polymorphic forms of zaleplon (N[3-(3-cyanopyrazolo[1,5a]pyrimidin-7-yl)phenyl]-N-ethylacetamide), methods for the preparation thereof, and their uses as anxiolytic, antiepileptic, and sedative-hypnotic agents and skeletal muscle relaxants.
Patent CA-2505598-A1 (CA)
Inventor: WEST MICHAEL D
IPC: A61K35/12
Filed: 2003-05-27
Abstract: Methods for producing stem cell banks, preferably human, which optionally may be transgenic, e.g., comprised of homozygous MHC allele cell lines are provided. These cells are produced preferably from parthenogenic, IVF, or same-species or cross-species nuclear transfer embryos or by de-differentiation of somatic cells by cytoplasm transfer. Methods for using these stem cell banks for producing stem and differentiated cells for therapy, especially acute therapies, and for screening for drugs for disease treatment are also provide.
Patent CA-2506889-A1 (CA)
Title: Protection a pli pour modules de filtration en spirale utilisant un adhesif traite aux uv, et procede de realisation correspondant
Inventor: CHENG HAITAO
IPC: B01D67/00
Filed: 2003-11-04
Abstract: L'invention concerne un paquet de feuilles (16) utile pour la réalisation d'un module de filtration en spirale. La zone de pli du paquet (16) est renforcée par le biais d'un adhésif traité aux UV (18). L'invention concerne également un module de filtration en spirale, dans lequel la ligne de pli, les lignes d'assemblage latéral (28) et/ou les lignes d'assemblage axial (30) des membranes (10) sont renforcées par le biais d'un adhésif pouvant être traité aux UV (18). L'invention concerne enfin le procédé qui permet de réaliser le paquet de feuilles (16) et les modules de filtration en spirale considérés.¿ ?
Patent CA-2507196-A1 (CA)
Inventor: HASSLER WILLIAM L JR
IPC: A61M1/10
Filed: 2005-05-12
Abstract: A remotely controlled gastric band system that is practically immune to external magnetic fields, such as from a Magnetic Resonance Imaging (MRI) machine, incorporates a bi-directional pump and fluid reservoir to adjust fluid volume in a gastric band. A piezoelectrically driven (e.g., rotary actuator, linear actuator) selectively compresses and expands a metal bellows hermetically sealed within a biocompatible and nonferromagnetic case such as titanium.
Patent CA-2509170-A1 (CA)
Title: Substituted 3-alkyl and 3-arylalkyl 1h-indol-1-yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1)
Inventor: JENNINGS LEE DALTON
IPC: C07D409/06
Filed: 2003-12-09
Abstract: The invention formula (1) substituted 3-alkyl and 3 arylalkyl 1H indol-1yl acetic acid derivatives which are useful as inhibitors of plasminogen activator inhibitor (PAI-1) useful for treating fibrinolytic disorders, the compounds having the structure wherein: R1, R2, R3, R4, R5, R6, and R7 are as defined herein or a pharmaceutically acceptable salt or ester form thereof.
Patent CA-2509937-A1 (CA)
Title: Program guide system with video-on-demand browsing
Inventor: ELLIS MICHAEL D
IPC: H04N21/475
Filed: 1999-05-18
Abstract: An interactive television program guide system is provided in which a viewer may direct a television to simultaneously display a selected television program and a program guide display. A viewer may use the program guide display to browse available video-on-dema nd (VOD) while continuing to view a previously selected program in the background. Th e viewer may browse through video-on-demand programs on the program guide display using a variety of keys on a remote control unit. The viewer may direct the program guide to order a given video-on-demand program, and set a desired broadcast time for that program.< /SDOAB>
Patent CA-2510918-A1 (CA)
Inventor: HUFFMASTER ANDREW
IPC: A61B17/122
Filed: 2003-08-29
Abstract: L'invention a trait à des procédés et à des dispositifs permettant d'obtenir un dispositif médical destiné à être utilisé dans l'espace sous-arachnoïdien. Ledit dispositif médical peut être un cathéter-guide comportant des éléments d'ancrage ou d'autres mécanismes permettant de le fixer à un emplacement ou dans une voie de l'espace sous-arachnoïdien. Dans certains modes de réalisation, le dispositif médical peut comprendre de multiples éléments d'articulation pouvant passer les uns à travers les autres, un ou plusieurs des éléments d'articulation comprenant un élément d'ancrage.
Patent CA-2511719-A1 (CA)
Inventor: SCELIA RICHARD P
IPC: A23L7/157
Filed: 2005-07-06
Abstract: A method for manufacturing bread crumbs is provided which does not use a conventional staling step. The ingredients of bread dough are mixed together and baked to form bread loaves. The unstaled bread is then subjected to a heat conditioning step to create a bread crumb product with qualities similar to bread crumb products produced using a conventional staling step. Thereafter, the bread may be further processed to form smaller bread crumbs, dried, and packaged for sale. As a result, no time-consuming staling step is needed in order to produce a bread crumb product having desirable qualities similar to those of bread crumb products that have been subjected to a conventional staling step.
Patent CA-2514908-A1 (CA)
Title: Substituted amino heterocycles as vr-1 antagonists for treating pain
Inventor: FLETCHER STEPHEN ROBERT
IPC: A61P25/04
Filed: 2004-02-20
Abstract: The present invention provides compounds of formula I: in which: one of T1and T4 is N and the other is C; T2 and T3 are independently N or C(CH2)nR2; X, Y  and Z are independently N or C(CH2)nR3; R1 is Ar1 or R1 is C1-6alkyl optionally substituted with one or two groups Ar1; Ar1 is an optionally substituted cyclohexyl, piperidinyl, piperazinyl, morpholinyl, adamantyl, phenyl, naphthyl, a six-membered heteroaromatic ring containing one, two or three nitrogen atoms, a five-membered heteroaromatic ring containing one, two, three or four heteroatoms chosen from O, N and S, at most one O or S atom being present, or a nine- or ten-membered bicyclic heteroaromatic ring in which phenyl or a six-membered heteroaromatic ring as defined above is fused to a six-or five-membered heteroaromatic ring as defined above; Ar is an optionally substituted phenyl, a six-membered heteroaromatic ring containing one, two or three nitrogen atoms or a five-membered heteroaromatic ring containing one, two, three or four heteroatoms chosen from O, N and S, at most one heteroatom being O or S, Ar being optionally substituted by one, two or three groups chosen from halogen, CF3, OCF3, C1-6alkyl, C2-6alkenyl, C2-6alkynyl, nitro, cyano, isonitrile, hydroxy, C1-6alkoxy, C1-6alkylthio, -NR6R7, -CONR6R7, -COH, CO2H, C1-6alkoxycarbonyl, haloC1-6alkyl, hydroxyC1-6alkyl, aminoC1-6alkyl, C1-6alkylcarbonyl and a five-membered heteroaromatic ring containing one, two, three or four heteroatoms chosen from O, N and S, at most one heteroatom being O or S, optionally substituted by C1-6alkyl, halogen, amino, hydroxy or cyano; or a pharmaceutically acceptable salt thereof as a VR-1 ligand; pharmaceutical compositions comprising it; its use in therapy; use of it in the manufacture of a medicament to treat pain; and methods of treating subjects suffering from pain.
Patent CA-2516249-A1 (CA)
Title: Decision feedback equalizer for digital tv and method thereof
Inventor: KIM SEUNG-WON
IPC: H03M13/25
Filed: 2004-02-11
Abstract: The conventional decision feedback equalizer has a drawback that can~t decide symbols correctly because a simple slicer is used as a symbol detector. A  decision feedback equalizer as a symbol detector uses a Trellis Coded Modulation (TCM) decoder whose Trace Back depth is 1 (TBD=1), to thereby decide symbols correctly without decoding delay.
Patent CA-2516417-A1 (CA)
Inventor: BRIZIO ADRIANA
IPC: B65D81/32
Filed: 2004-02-11
Abstract: L'invention concerne une boîte comprenant une première chambre (38) vide au départ et prête à l'emploi, située juste sous le couvercle et conçue pour recevoir la boisson finale, séparée par une cloison étanche (14 ; 214 ; 314) d'une seconde chambre (16) contenant un liquide buvable (18). La cloison étanche présente un logement (20 ; 120 ; 220 ; 334) conçu de manière à recevoir un filtre (24 ;124) monté sur un tube (22 ; 122) conçu pour être plongé à l'intérieur de la chambre (16) contenant le liquide buvable (18). Des moyens permettent au consommateur de manipuler le filtre (24 ; 124) de façon à établir une connexion entre les deux chambres (38 et 16) par l'intermédiaire dudit filtre (24 ; 124). Ainsi, lorsque l'on place la boîte à proximité d'une source de chaleur et que la connexion a été établie entre les deux chambres (38 et 16), le liquide contenu dans la chambre inférieure (16) passe dans la première chambre (38) par la substance (28) contenue dans le filtre (24 ; 124) et la boisson est ainsi obtenue.
Patent CA-2517600-A1 (CA)
Inventor: BALABAN NAOMI
IPC: A61K38/08
Filed: 2004-01-30
Abstract: The invention features methods and compositions for treatment or prevention of infection by, or disease caused by infection with, certain species of bacteria, including in particular bacteria in which a RAP-type and/or TRAP-type molecule plays a role in pathogenesis. This includes Staphylococcus species.
Patent CA-2518440-A1 (CA)
Title: Microemulsions as adjuvants for agricultural chemicals
Inventor: MICHAIL DIANNE
IPC: A01N25/04
Filed: 2004-03-11
Abstract: A microemulsion composition is provided for use as an adjuvant with agrochemicals, comprising an oil phase component, a hydrophilic emulsifier, a lipophilic co-emulsifier and water.
Patent CA-2519197-A1 (CA)
Inventor: ROHART EMMANUEL
IPC: C01F17/229
Filed: 2004-03-17
Abstract: La composition de l'invention, selon un premier mode de réalisation, consist e essentiellement en un oxyde de cérium et en un oxyde de zirconium. Selon un second mode de réalisation, cette composition est à base d'un oxyde de cériu m, d'un oxyde de zirconium et d'au moins un oxyde d'une terre rare autre que le cérium. Après une première calcination à 900~C pendant 4 heures puis une seconde calcination à 1000~C pendant 10 heures, elle présente une variation de sa surface spécifique d'au plus 20% dans le cas du premier mode et d'au plus 15% dans le cas du second. La composition de l'invention peut être utilisée comme catalyseur notamment pour le traitement des gaz d'échappement des moteurs à combustion interne.
Patent CA-2520491-A1 (CA)
Inventor: IVERSEN BJORN FRANC
IPC: A61F2/38
Filed: 2004-03-24
Abstract: A system for ensuring correct insertion and spatial orientation of a prosthesis cup and / or a prosthesis neck of an artificial hip joint is described. The system comprises a tool (30) for controlling the mutual positioning of the main components in a femoral prosthesis; a measuring device (40) for measuring the distance between two supports (2, 2') connected to the patient s pelvis and femur; and a positioning tool (1) designed to be releasably connected to a handle part (14) connected to the tool according to item a) and to the two supports connected to the patients pelvis and femur. A  measuring device and a positioning tool included in the system is also described in addition to a method for surgery by means of the present tools.
Patent CA-2521234-A1 (CA)
Title: Endomedullary nail for the treatment of proximal femur fractures
Inventor: RENZI BRIVIO LODOVICO
IPC: A61B17/76
Filed: 2005-09-26
Abstract: An endomedullary nail for the treatment of proximal femur fractures, comprising an elongate body (12) having a proximal portion (14) and a distal portion (16). The proximal portion (14) has a first and a second hole (20, 21) for a respective cephalic screw (22, 23, 24, 25), each having a transversal axis to the axis of the proximal portion (14). The first hole (20) is split into two passages each having a respective axis (A, B) with. a predetermined angle relationship with respect to the axis (C) of the second hole (21). The passages (30, 31) are arranged to be selectively engaged by a respective cephalic screw (22, 24).
Patent CA-2522649-A1 (CA)
Inventor: LI WEIWEI
IPC: C07K16/28
Filed: 2004-04-16
Abstract: The invention provides methods for treating diseases involving aberrant amyloid-.beta. (A.beta.) peptide deposition, including Alzheimer~s Disease, by the administration of Nogo receptor antagonists. The invention also provides method for reducing levels of A.beta. peptide in a mammal by the administration of soluble Nogo receptor polypeptides
Patent CA-2522695-A1 (CA)
Inventor: FREEMAN NORMAN A
IPC: G01R31/00
Filed: 2004-05-14
Abstract: The electrical energy produced by a fuel cell under test is typically dumped in the form of heat energy radiated from a controllable variable load included in a conventional fuel cell testing system. This practice is wasteful since the electrical energy produced is not immediately employed to do useful work, stored for later use or sold to a power company after appropriate conversion.  According to aspects of some embodiments of the present invention there is provided a fuel cell testing system having an energy conversion system that converts electrical energy produced by a fuel cell under test into another reliable form of energy that can be employed for some useful end, as opposed to simply dumping it as radiated heat energy.
Patent CA-2525232-A1 (CA)
Title: Signal-to-noise estimation in wireless communication devices with receive diversity
Inventor: ABRISHAMKAR FARROKH
IPC: H04B1/10
Filed: 2004-05-28
Abstract: This disclosure is directed to techniques for estimating signal-to-noise ratio (SNR) of signals received by a wireless communication device. The techniques take advantage of spatial receive diversity in a wireless communication device to achieve accurate estimates of SNR. In general, a spatial projection wiener filter function can be applied to incoming symbol estimates to support efficient computation of SNR. The estimated SNR can be used to produce power control commands for use in forward power control.
Patent CA-2525724-A1 (CA)
Title: Modification of a projectile for stacking in a barrel
Inventor: O'DWYER JAMES MICHAEL
IPC: F41A19/65
Filed: 2004-05-13
Abstract: An existing projectile (21) is modified by adding a tail piece (22) to enable axial stacking of multiple projectiles (20) in a common barrel. Propellant for each modified projectile (20) is contained in respective chambers located external to the barrel and connected to the bore of the barrel through associated ports. Tail piece (22) aligns with a respective port and provides a space between consecutive projectiles (20) into which the propellant gas expands after ignition. Separate claims are directed to tail assembly (22), modified projectile (20), the barrel assembly having a plurality of projectiles (20) stacked in end-to-end relation, and to an external initiation system for the barrel assembly (see Figures 4, 7).