baber/WOPTO huggingface dataset:
Patent CA-2408112-A1 (CA)
Inventor: HEALY MICHAEL SEAN
IPC: A61K33/30
Filed: 2001-04-30
Abstract: L'invention concerne une composition liquide, hydrophobe, sensiblement anhydre, destinée à la protection de la peau, qui se présente sous forme de pompe de vaporisation. Conçue pour être vaporisée directement sur la peau, cette composition adhère à la peau et résiste à l'écoulement. Elle contient une ou plusieurs substances actives quelle que soit l'indication pour laquelle la composition a été préparée, un ou plusieurs modificateurs rhéologiques, et un support. Les modificateurs rhéologiques contribuent à conférer à la composition des propriétés rhéologiques telles qu'elle puisse être vaporisée à l'aide d'un distributeur à pompe de vaporisation (c.-à-d. un distributeur sans gaz propulsif et non pressurisé) tout en résistant à l'écoulement après application sur la peau. Les modificateurs rhéologiques peuvent être des cires et/ou des épaississants associatifs, tels que certaines formes de silice. Le support peut être de l'huile minérale ou un succédané d'huile minérale (p. ex. isohexadécane, cyclométhicone). Des éléments filmants favorisent également la résistance de la composition à l'écoulement. Une indication pour laquelle la composition peut être préparée est l'érythème fessier. La composition contre l'érythème fessier est conçue pour être vaporisée sur la peau d'un bébé ou d'un autre être humain (tel qu'un adulte incontinent) pour traiter l'érythème fessier. Le principe actif pour l'érythème fessier peut être diméthicone mais également, de préférence, de l'oxyde de zinc.
Patent CA-2408404-A1 (CA)
Inventor: MORRIS ANDREW R
IPC: B26D7/22
Filed: 2001-05-09
Abstract: L'invention concerne un appareil de perforation (10) d'une bande continue, lequel comprend un système destiné à détecter et indiquer qu'une lame de l'appareil est cassée, non affûtée, ou autre, et qu'elle ne perfore pas la bande. Cet appareil comprend au moins un contre-outil (80) comportant un support de lame (42) ainsi qu'une contre-lame (45) positionnée dans le support de lame, lequel est formé dans un matériau isolant de manière à isoler électriquement la contre-lame, du cadre machine du dispositif de bobinage. Un conducteur électrique est couplé à la contre-lame de façon à fournir un courant électrique à celle-ci, à partir d'une source de courant. Cet appareil comprend encore au moins une lame perforante (21), mise à la terre, destinée à se déplacer par rapport à la contre-lame et coopérant avec cette contre-lame pour perforer une bande au niveau de points déterminés sur la longueur de cette bande, la lame perforante entrant en contact avec la contre-lame après perforation de la bande. Un circuit fermé est formé et conservé le long de la contre-lame au niveau des points où les lames entrent en contact l'une avec l'autre.
Patent CA-2408571-A1 (CA)
Inventor: PARHAM CHRISTI L
IPC: A61K38/08
Filed: 2001-05-10
Abstract: La présente invention concerne des acides nucléiques codant pour des récepteurs de mammifères, par exemple des primates, des protéines de récepteur purifiées et de fragments de celles-ci. Cette invention concerne aussi des anticorps, polyclonaux et monoclonaux. Cette invention concerne enfin des techniques d'utilisation de compositions destinées au diagnostic et à la thérapie.
Patent CA-2410436-A1 (CA)
Title: Method of diagnosing, monitoring, staging, imaging and treating colon cancer
Inventor: PLUTA JASON
IPC: C12Q1/68
Filed: 2001-05-29
Abstract: The invention relates to CSG polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.
Patent CA-2413297-A1 (CA)
Title: Hand-held surgical instruments with omni-circumferential actuation capabilities
Inventor: POSTEL ERIC A
IPC: A61B17/28
Filed: 2002-03-29
Abstract: Hand-held instruments have an actuator assembly which may be employed to actuate a distally mounted tool by application of radial force about the entirety of the instrument circumference (i.e., is omni-actuatable). Most preferably, the actuator assembly (10-1) includes a plurality of circumferentially spaced-apart generally L-shaped actuator levers (20) defining respective arcuate bearing surfaces (22-1) along exterior edge regions thereof, and a retaining ring (22) which circumferentially bounds the actuator levers around the exterior edge regions thereof. The retaining ring most preferably defines an interior stationary arcuate guide surface (20-3) in conformable mated relationship to the bearing surfaces (22-1) of said actuator levers. Radial force applied to the proximally extending arm sections of the levers thereby responsively causes the bearing surfaces thereof to be slideably moved along the guide surface of said retaining ring so as to translate such radial force into longitudinal movements of an elongate actuation pin (18) between retracted and extended positions thereof. By providing a tool which operatively coacts with the actuation pin, a surgeon may actuate the tool as needed by applying radial force at any point about the circumference of the actuator assembly.
Patent CA-2415394-A1 (CA)
Title: Ensemble siege pour vehicule a moteur ayant une colonne de ceinture de securite orientable
Inventor: TAME OMAR D
IPC: B60N2/30
Filed: 2001-07-13
Abstract: L'invention concerne un ensemble siège de véhicule à moteur comprenant un coussin de siège qui est fonctionnellement relié au véhicule à moteur. Le coussin de siège supporte un passager sur l'ensemble siège. Un dossier de siège est couplé pivotant audit coussin. Ledit dossier se déplace entre une position assise généralement droite et une position penchée vers l'avant, le dossier du siège étant alors contre le coussin de siège. Une colonne de ceinture diagonale est fixée à demeure au dossier de siège et supporte une ceinture diagonale. La colonne comporte une base et une extension de colonne. L'extension de colonne est en prise coulissante avec la base de colonne. Un dispositif de positionnement, relié entre la base et l'extension de colonne, coulisse automatiquement l'extension de colonne entre une position d'emploi se prolongeant hors du dossier de siège, la ceinture diagonale se positionnant alors au-dessus du dossier de siège, et une position de rangement logée à l'intérieur du dossier de siège.
Patent CA-2421035-A1 (CA)
Title: A surfactant system comprising alkyl pyrrolidone and alkyl polysaccharide
Inventor: SAVA ALEX
IPC: A61L2/18
Filed: 2001-08-30
Abstract: The invention relates to an aqueous composition comprising in combination an alkyl pyrrolidone, such as a C8-C18 linear alkyl pyrrolidone, and an alkyl polysaccharide such as an alkyl polyglucoside, and a method of enhancing the efficacy of an enzyme containing composition for use in cleaning medical instruments comprising the step of including in said composition an alkyl pyrrolidone and an alkyl polysaccharide. The methods and compositions of the present invention may further include at least one enzyme such as proteases, lipases, amylases, and cellulases.
Patent CA-2421343-A1 (CA)
Inventor: SEIBERT CLAUS
IPC: G03F7/23
Filed: 2003-03-07
Abstract: Described is a method for imaging a printing form (10) using tine or more laser diode bars having a number n of individually controllable laser diodes (16) whose imaging spots (20) lie essentially in a row on the printing form (10), for the case that at least one laser diode (16) on the laser diode bar (14) cannot be activated, but a maximum number m of laser diodes (16) whose neighboring imaging spots (20) have a distance a on the printing form (10) are able to be activated. The relative speed between the imaging device (12) and the printing form (10) is increased by the factor (n/m). The exposure time per printing dot (69) is shortened by the factor (m/n). In order to input in each case an amount of energy per printing dot (69) on the printing form (10), imaging is carried out using the m activatable laser diodes (16) with an imaging intensity which is a function of the exposure time and of the specific amount of energy per printing dot (69).
Patent CA-2421717-A1 (CA)
Inventor: KITAO SATOSHI
IPC: A24D1/00
Filed: 2001-09-07
Abstract: A method of producing a low flame propagation cigarette wherein, even if the  lighted cigarette is left on a combustible material, the self-extinguishing action of a combustion adjusting agent or the removal of heat of combustion by the combustible material prevents scorching from occurring in the combustibl e material or from advancing so much as in the past; and a device for producin g a low flame propagation cigarette. The device of producing a low flame propagation cigarette comprises a combustion adjusting agent applied region forming unit (30, 30') for forming combustion adjusting agent applied region s in a plurality of longitudinally or peripherally spaced positions in a wrapping paper web (20a) being conveyed on a wrapping paper conveyer unit (18), a unit (14) for feeding cut tobacco to the wrapping paper having been formed with the combustion adjusting agent applied regions, a wrapping tube unit (23) for wrapping the wrapping paper having cut tobacco fed thereto int o a cigarette form, and a cigarette cutting unit (28) for cutting the wrapping  paper wrapped into a cigarette form into lengths corresponding to the length  of a cigarette.
Patent CA-2421847-A1 (CA)
Title: Method and apparatus for welding pipes together
Inventor: BELLONI ANTONIO
IPC: B23K9/00
Filed: 2001-10-22
Abstract: A method of laying a pipeline (6) underwater includes the steps of holding an end of a pipeline (6), providing a pipe section (5) for extending the pipeline (6), arranging the pipe section (5) adjacent to said end of pipeline (6) thereby defining a circumferential joint (7) to be welded, and welding the pipes (5, 6) together. A plurality of welding torches (9) move along the circumferential joint (7) and are operated simultaneously to weld the pipes together. The pipes (5, 6) are made of TMCP--AC steel (steel manufactured using a thermal mechanical control process with accelerated cooling and having a carbon content of less than 0.1% by weight). After the root weld is laid, a cooling ring (1) mounted on an internal clamp inside the pipes (5, 6) sprays cooling liquid, for example a fluid spray of atomised water (10) and air, from nozzles (2) onto an interior surface of the pipes (5, 6) in the region of the circumferential joint (7), thereby cooling the pipes (5, 6).
Patent CA-2421874-A1 (CA)
Inventor: BIGGINS PETER DOUGLAS
IPC: G16Z99/00
Filed: 2001-06-01
Abstract: A system for monitoring a live population uses a unit (1) as a local data collection means to derive data on the physical condition of a population member (2). The unit (1) has a local processor (6) for correlating and storing the physical condition data relative to time, and means (7) for transferring the stored data from the local processor (6) to a remote data collection means (3). The remote data collection means also receives data relating to the location of the population member (2) relative to time, and analyses the physical condition and location data for unusual events, providing a signal on the occurrence of an unusual event. The physical condition may be derived from a sensor (4), which is a non-invasive sensor for measuring pulse rate, temperature and oxygen levels. The location data is provided from a location means (5) incorporated in the unit (1).
Patent CA-2429634-A1 (CA)
Inventor: HASS BARRY L
IPC: H04L12/56
Filed: 2001-11-19
Abstract: There is disclosed an apparatus and method for limiting tunnel traffic in a network. Traffic engineering tunnels are used to direct traffic along a predefined path, which may differ from the path that internet protocol (IP) routing would determine. Interior gateway rotocol ((IGP) cut through will allow the forwarding of all destinations downstream of a tunnel through the tunnel, without the operator needing to specify a forwarding equivalence class (FEC). But congestion in the tunnel and network instability may result from this approach. A solution to these problems is disclosed which limits the traffic in the tunnel to only that with destination addresses of the tunnel's egress router or nodes directly supported thereby. Other solutions are disclosed which allow tunnel traffic to nodes having destination addresses other than those being directly supported by the tunnel's egress router. All of these solutions are achieved in both pre-determined forwarding entry and dynamic packet-by packet embodiments.
Patent CA-2430135-A1 (CA)
Title: Recombinant anti-cd30 antibodies and uses thereof
Inventor: FRANCISCO JOSEPH A
IPC: C07K19/00
Filed: 2001-11-28
Abstract: The present invention relates to methods and compositions for the treatment of Hodgkin's Disease, comprising administering proteins characterized by their ability to bind to CD30, or compete with monoclonal antibodies AC10 or HeFi-1 for binding to CD30, and exert a cytostatic or cytotoxic effect on Hodgkin's Disease cells. Such proteins include derivatives of monoclonal antibodies AC10 and HeFi-1. The proteins of the invention can be human, humanized, or chimeric antibodies; further, they can be conjugated to cytotoxic agents such as chemotherapeutic drugs. The invention further relates to nucleic acids encoding the proteins of the invention. The invention yet further relates to a method for identifying an anti-CD30 antibody useful for the treatment or prevention of Hodgkin's Disease.
Patent CA-2430675-A1 (CA)
Inventor: HICKS KEITH B
IPC: A01G23/091
Filed: 2003-05-30
Abstract: A tree harvesting apparatus is provided. The harvesting apparatus comprises a frame member, a cutting device mounted to the frame member, and at least one cutting member attached to the cutting device. A base member partially overlays the cutting device. A tree accumulation member is positioned adjacent the base member and is co-planar therewith and extends over at leas t a portion of the cutting member.
Patent CA-2431553-A1 (CA)
Title: Cxcr3 antagonists
Inventor: LI AN-RONG
IPC: A61P25/00
Filed: 2001-12-11
Abstract: Compounds, compositions and methods that are useful in the treatment of inflammatory and immune conditions and diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of a chemokine receptor. The subject methods are useful for the treatment of inflammatory and immunoregulatory disorders and diseases, such as multiple sclerosis, rheumatoid arthritis and type I diabetes.
Patent CA-2432409-A1 (CA)
Title: Tropolone derivative
Inventor: KAGECHIKA HIROYUKI
IPC: C07D333/22
Filed: 2001-12-18
Abstract: A tropolone derivative represented by the formula (I) which has retinoid activity and is useful as an active ingredient for medicines [R1 to R4 each represents hydrogen, alkyl, or alkoxy; ring Ar represents an aryl ring or heteroaryl ring; X represents a single bond, -N=N-, -CON(R5)-, -(C=C)nCON(R6 )- , -N(R7)CON(R8)-, -SO2N(R9)-, -N(R10)- (R5 to R9 each represents hydrogen or  alkyl, n is 1 to 3, and R10 represents hydrogen, alkyl, or acyl), alkylene, arylene, or heterocyclic-diyl; and Y represents hydrogen, -OR11 (R11 represents hydrogen, alkyl, or acyl), -NHR12 (R12 represents hydrogen, alkyl , acyl, or amino), or halogeno]. (I)
Patent CA-2432883-A1 (CA)
Title: Antigenic ck-18 compounds for therapy and diagnosis and methods for using same
Inventor: NICOLETTE CHARLES A
IPC: C12Q1/689
Filed: 2001-12-21
Abstract: The present invention provides methods and compositions for detecting, diagnosing, prognosing and monitoring the progress of CK-18-related cancers and malignancies and kits for use in said methods. Further provided are methods for screening to identify agonists and antagonists of cancer antigen s associated with CK-18 related cancers and malignancies.
Patent CA-2433833-A1 (CA)
Title: Use of flumazenil in developing a drug for the treatment of alcohol dependence
Inventor: LEGARDA IBANEZ JUAN JOSE
IPC: A61P25/32
Filed: 2002-01-10
Abstract: The invention relates to the use of flumazenil in developing a drug used for the sequential administration of small quantities of flumazenil at short intervals, until a therapeutically effective quantity is administered to treat alcohol dependence.
Patent CA-2434246-A1 (CA)
Title: Silylated polyurethane-urea compositions for use in cosmetic applications
Inventor: KREPSKI LARRY R
IPC: A61Q1/02
Filed: 2001-05-24
Abstract: A composition in the form of an aqueous dispersion used in cosmetic applications is provided. The composition comprises at least one polyurethan e- urea polymer that is functionalized with at least one hydrolyzed or hydrolyzable silyl group. When the composition is used in hair care, it does  not have a reshapable effect.
Patent CA-2438135-A1 (CA)
Inventor: DI CIOCCIO MARK ANTHONY
IPC: F04D29/62
Filed: 2002-02-15
Abstract: A device comprising a rotor (3) and fan (2) rotatably mounted on a shaft (4) which his rigidly fixed relative to a vehicle surface. The device is fixable on a vehicle surface by means of two clamping portions (18, 20) which are moveable towards each other along the shaft (4) to press against a surface between them.
Patent CA-2438157-A1 (CA)
Inventor: GUINTHER GREGORY H
IPC: C10L10/04
Filed: 2003-08-25
Abstract: A method of reducing the negative effects of accumulation of ash in a diesel fuel combustion system includes supplying a diesel fuel having an additive that includes a manganese compound to a diesel fuel combustion system. The combustion system includes a catalyzed diesel particulate filter or, alternatively, a continuously regenerating technology diesel particulate filter. The fuel is then combusted in the combustion system to product at least one byproduct that includes the manganese compound. The manganese compound is supplied in an amount effective to complex with the combustion byproduct.
Patent CA-2438768-A1 (CA)
Inventor: POPP KARL F
IPC: A61K47/44
Filed: 1992-01-31
Abstract: Film-forming flexible collodion compositions can be improved by including one or more topically acceptable polymers in an amount sufficient to increase the resilience of the film formed. Suitable polymers include polyalkylenes and (meth)acrylate homo-or copolymers. Preferred embodiments include isobutene-butene copolymer and/or polymethyl methacrylate. The compositions can further include salicylic acid and a topically acceptable crystallization inhibitor in an amount sufficient to suppress the crystallization of dissolved salicylic acid from the composition. Suitable crystallization inhibitors include at least one mono- or polyester and/or ether. Preferred embodiments include a mixture of ethyl lactate and castor oil, and ethyl lactate alone.  The compositions preferably also contain a local anesthetic.
Patent CA-2438876-A1 (CA)
Title: Novel carotenoid esters
Inventor: BINNINGTON RICHARD H
IPC: C11B1/00
Filed: 2002-02-22
Abstract: Monoesters, diesters and polyesters are provided wherein both the acid-derived moiety and the alcohol-derived moiety of the esters are carotenoid compounds.  The synthetic ester linkage between two or more carotenoids provides new compounds in which the similar and complementary properties of the individual carotenoids are combined. The new all-carotenoid esters may be useful as antioxidants, therapeutic agents, pigmenting ingredients in poultry feed or as coloring agents for fats. The polyesters have the potential to act as molecular wires with unique electrical conductance characteristics. The all-carotenoid esters may be prepared from the esterification of at least one hydroxy carotenoid with at least one carboxylic carotenoid, or via the reaction of the acid chloride of a carboxylic carotenoid with a hydroxy carotenoid. Preferred hydroxy carotenoids include lutein, zeaxanthin, cryptoxanthin, violaxanthin, carotene diol, hydroxy carotene, hydroxylcopene, alloxanthin and dehydrocryptoxanthin. Preferred caroxylic carotenoids include bixin, norbixin, .beta.-apo-8-carotenoic acid, crocetin, diapocarotenoic acid, carboxylcarotene and azafrin.
Patent CA-2440411-A1 (CA)
Title: Process for preparation of optically active propoxyaniline derivatives
Inventor: YAGI TSUTOMU
IPC: C12P17/18
Filed: 2002-03-06
Abstract: Treatment of a racemic lactate derivative with an enzyme having an ability to hydrolyze an ester asymmetrically causes specific hydrolysis of the ester moiety of one of the optical isomers constituting the racemic lactate derivative, and use of the resulting hydrolyzate as an intermediate enables the preparation of an optically active propoxyaniline derivative in a decreased number of steps as compared with the prior art. (A)
Patent CA-2441289-A1 (CA)
Title: Methode de traitement therapeutique d'une forme cliniquement identifiee de cardiopathie chez un mammifere vivant
Inventor: MORGAN JAMES P
IPC: A61K35/12
Filed: 2002-03-14
Abstract: La présente invention concerne des méthodes thérapeutiques faisant appel à un ou plusieurs type(s) identifiable(s) de cellules souches mammaliennes et/ou de cellules progénitrices qui en sont issues, et/ou de cellules issues de leurs lignées, et/ou de cellules partiellement différenciées issues desdites cellules souches avec ou sans cellules totalement différenciées dans le but de traiter des mammifères souffrant d'une forme de cardiopathie cliniquement identifiée. Les types de cellules identifiables comprennent des cellules souches embryonnaires et les cellules qui en sont issues, les types de cellules souches adultes actuellement identifiés et les différentes cellules qui en sont issues, ainsi que des types de cellules alternatives identifiés récemment et présentant des propriétés fonctionnelles de cellules souches. Parmi les formes cliniques de cardiopathies qui peuvent être traitées efficacement au moyen des méthodes thérapeutiques selon la présente invention figurent l'infarctus du myocarde, la myocardite, l'insuffisance cardiaque et la dysrythmie cardiaque.
Patent CA-2442666-A1 (CA)
Title: Fibre optic well control system
Inventor: WILLIAMS GLYNN R
IPC: E21B47/12
Filed: 2003-09-25
Abstract: In a hydrocarbon production well, a control processor 32 selectively sends light to each of one or more gas lift valves 28 to cause injection of an injection fluid (such as nitrogen gas) from a pressurised annulus 22 into a production fluid (hydrocarbon) in production 18 tubing, and/or to each of one or more inlet valves 60, to control the rate of flow of the hydrocarbon (oil). The control processor 32 receives feedback data from sensors 48 54 50 66 near to each gas lift 28 or inlet 60 valve and otherwise provided in the well bore which measure pressure, temperature or flow rate. The sensors communicate by sensor fibre optic lines 42 which run in the well bore 10. The control processor 32 sends control signals by operating a laser light source to selectively to send laser light to each valve 28 60 through valve operating light fibres 36 which also run through the well bore 10. The valves 28 60 derive their motive power from the laser light using a photovoltaic cell array 58 which drives an actuator 68 which can be piezo electric, an electric motor or solenoid.
Patent CA-2448360-A1 (CA)
Title: Modulation of cell division by an early mitotic inhibitor protein
Inventor: JACKSON PETER K
IPC: C07K14/46
Filed: 2002-05-23
Abstract: Emi1 regulates progression through early mitosis by preventing premature APC  activation. Depleting Emi1 from cycling cells strongly delays cyclin B  accumulation and mitotic entry, while expression of a stabilized form of Emi1 stabilizes APC substrates and causes a mitotic block. Emi1 binds the APC  activators Cdc20 and Cdh1 and inhibits APC activation by Cdc20 or Cdh1. Hence, products that modulate the expression and/or activity of Emi1 have a therapeutic effect in the treatment of cancer, leukemia, solid tumors, chronic or acute inflammatory disease, restenosis, diabetes, neurological disorders, arthritis and osteoporosis, among other indications.