baber/WOPTO huggingface dataset:
Patent WO-2010107397-A1 (WO)
Title: Modulateurs de l'apoptose et leurs utilisations
Inventor: LIM BING
IPC: C12N15/09
Filed: 2010-03-17
Abstract: La présente invention concerne miR-125b, un micro-ARN enrichi de cerveau, qui est un régulateur négatif de p53 chez les animaux. La régulation à la baisse de p53 médiée par miR-125b dépend de la liaison de miR-125b à un élément de réponse de micro-ARN dans les 39 régions non traduites de l'ARNm de p53. La surexpression de miR-125b réprime le niveau endogène de la protéine p53 et supprime l'apoptose dans les cellules. En revanche, l'inactivation de miR-125b augmente le niveau de la protéine p53 et induit l'apoptose dans les cellules. Ce phénotype peut être considérablement corrigé par une ablation de la fonction de p53 endogène ou de l'expression ectopique de miR-125b chez le dard-perche. L'expression ectopique de miR-125b supprime l'augmentation de p53 et l'apoptose induite par le stress. Notre étude met en évidence que miR-125b est un important régulateur négatif de p53 et de l'apoptose induite par p53 durant le développement et durant la réponse au stress.
Patent SG-181410-A1 (SG)
Title: A composition for treating diabetes and a process thereof
Inventor: Zhang bao yu
Filed: 2010-04-15
Abstract: The present invention relates to a herbal composition for treating diabetes, amethod for preparing said herbal composition~
Patent SG-166774-A1 (SG)
Title: Method and apparatus for achieving flexible bandwidth using variable guard bands
Inventor: KHANDEKAR AAMOD
Filed: 2006-10-27
Abstract: Techniques to flexibly support different bandwidths in a wireless communication system are described. The system supports a configurable operating bandwidth using a fixed design bandwidth and variable guard bands. Values for various parameters such as fast Fourier transform (FFT) size, cyclic prefix length, and sample rate may be selected based on the design bandwidth. The design bandwidth may be associated with K total subcarriers. Different operating bandwidths may be supported by selecting different numbers of usable subcarriers. A transmitter and a receiver may perform processing for a transmission using the same FFT size, cyclic prefix length, and sample rate regardless of the selected operating bandwidth. The system may use different operating bandwidths and/or different parameter values (e.g., FFT sizes) for different portions of a transmission, e.g., a preamble and a main body of the transmission.
Patent SG-182868-A1 (SG)
Title: Safety hypodermic needle assembly
Inventor: CHANG KOMAS
Filed: 2011-01-18
Abstract: OF THE DISCLOSURESAFETY HYPODERMIC NEEDLE ASSEMBLYA safety hypodermic needle assembly includes a metalneedle having a flange extending around the periphery thereof, a flexible plastic needle detachably attached to the metal needle, and a safety member mounted on the metal needle and receivable in the needle hub of the flexible plastic needle forprotecting the tip of the metal needle to avoid accidental injury after removal of the metal needle from the flexible plastic needle.FIG. 1
Patent SG-171764-A1 (SG)
Title: Purification of proteins
Inventor: MOYA WILSON
Filed: 2009-12-02
Abstract: The present invention relates to a bimodal polymer such as a soluble polymer capable of irreversibly binding to insoluble particulates and a subset of soluble impurities and also capable of reversibly binding to one or more desired biomolecules in an unclarified biological material containing stream and the methods of using such a material to purify one or more desired biomolecules from such a stream without the need for prior clarification. Such a polymer comprises domains of charged pendant groups such as primary, secondary, tertiary or quaternary amines, (first mode) and is rendered insoluble and precipitates out of solution simply upon complexing with oppositely charged solid particulates and a fraction of the soluble impurities in an amount sufficient to form an aggregate that can no longer be held in solution. The polymer further comprises other domains of pendant groups that are charged or uncharged, hydrophilic or hydrophobic or have a ligand that is selective for the biomolecule of interest depending on the process conditions such as pH, ionic strength, salts, and the like (second mode). When present in one mode, such as the uncharged form, said pendant groups are capable of binding to one or more desired biomolecules within the stream (protein, polypeptide, etc) in an unclarified cell broth. The precipitate can then be removed from the stream, such as by being filtered out from the remainder of the stream and the desired biomolecule is recovered such as by selective elution.
Patent SG-173364-A1 (SG)
Title: Compositions and methods for inhibiting growth of smad4-deficient cancers
Inventor: VIOLETTE SHELIA M
Filed: 2007-07-10
Abstract: - 88 -AintrimtCONIPOSITIONS ANDMETHODS FOR .INHIBITENG GROWTH OF SMAD4- DEFICIENT CANCERSThe partsE,&. itYvaLtion in the fiehts of e bislogy, irnausrsology nnntoIngy- The inveaticn 1),:•iata- to the din.‘,,,awsry :halt then: sa relataz‘as1.4 t‘stcysz•t th.T: er.49tin,s101k le:••(.`elt ,f ttLe tracr .:,upprencr rae .waad4 &n dlaWil at: dir.4.; .51.1.11 neir I 5t nti the lesvcnsis,cenet:s ofpoAiers: i....wilatrot:stotivpu-ac:ne l-orarinth and CO2.14:0::::iiO313tent:boa:es :tad ocn*- Lads Ti baai czNP6i, parti”flidar:;-„,n c rcea cells fram. snols ptytient papuLuEons, rusare cattition.aas .SISCh Ispisacrearic catInarilaa Thethus TADI:i&S iSierhndlOs etentthain the respaasi-.,ez-tesscitki:mor cells(prAtir thersta frots. ttna'n.7.. n.uoS r....cyz-apszat:t, _exam :reins the exptes:daa al- typo and .atnct4 tc; the ntrini ceii.;, as tzs.edil0.3 n.beitaSE:Cf 1fl$O2s- ad treattneattiateverrial ofomnr ptcgzetz:ion ligands,ci tanitaorlies aact stta.53.110-soloculs tbs-s 5± 1d to:::•ittesi.la ce.,. pis on th. ,nAtfasez DI t3.1.lio: ceiL emdrol that bloct ve c ncxe t.Toniponant&o the rap priticathits. m,aff4-cleficient tumortrc-c3 ti gime
Patent SG-177982-A1 (SG)
Title: Methods for treating psoriasis
Inventor: VALDES JOAQUIN MARIO
Filed: 2008-01-16
Abstract: This invention provides a method of treating psoriasis in a subject by administering to a subject an antibody capable of binding to the p40 subunit of IL-12 and/or IL23. Figure 1
Patent SG-178456-A1 (SG)
Title: Ketoreductase polypeptides for the preparation of phenylephrine
Inventor: ALVIZO OSCAR
Filed: 2010-08-19
Abstract: The disclosure relates to engineered ketoreductase polypeptides and processes of using the polypeptides for production of phenylephrine.
Patent SG-185239-A1 (SG)
Title: Method for identifying nucleic acids bound to an analyte
Inventor: STEPHEN R QUAKE
Filed: 2012-04-26
Abstract: 57A method for identifying a target nucleic acid bound by an analyte in a sample comprising: a) contacting said sample with a first probe comprising a first nucleic acid and a first analyte5 binding domain and a second probe comprising a second nucleic acid and second analyte binding domain, wherein said first and second probes are capable of binding to said analyte, such that said first and second nucleic acid are in spatial proximity to form a complex with said target nucleic acid if said target nucleic acid is bound by said analyte in said sample; b) incubating said sample with a ligase capable of ligating said complex to form a ligated target10 nucleic acid template; c) amplifying said target nucleic acid template if present in said sample, and d) detecting the presence or absence of an amplified target nucleic acid template.(Figure 1)
Patent SG-190545-A1 (SG)
Title: Leukocyte purification
Inventor: MIKHAIL FOMOVSKY
Filed: 2012-11-20
Abstract: OF DISCLOSUREA method for purifying leukocytes is disclosed. The method can further include recovering the purified leukocytes, or lysing the purified leukocytes.Figure 1
Patent SG-187473-A1 (SG)
Title: Powdered protein compositions and methods of making same
Inventor: ADLER MICHAEL
Filed: 2009-01-14
Abstract: A method for preparing a protein or peptide powder is provided that includes spray drying a solution including more than, e.g., about 50 mg/mL of a protein or peptide (e.g., an antibody or antigen binding portion thereof), and at least one excipient. Also provided are stable powdered compositions including a protein and an excipient having less than, e.g., about 6% of residual moisture. FIGURE 7
Patent SG-189286-A1 (SG)
Title: Fiber for artificial hair, and hair accessory formed from same
Inventor: HASHIMOTO TOMOMICHI
Filed: 2011-10-05
Abstract: The present invention relates to a polyvinyl chloride-based resin fiber having a shrinkage stress of 70 µN/dtex or less at 130°C. When fiber bundles for artificial hair which includes 20 to 100% by weight of this polyvinyl chloride-based resin fiber and 0 to 80% by weight of a thermoplastic resin fiber having a Young's modulus of 4 to 9 GPa and a shrinkage percentage of 10% or less at 130°C and having a composition including no polyvinyl chloride-based resin are processed, a fiber for artificial hair and an artificial hair product having an excellent styling property and texture similar to those of human hair can be obtained.
Patent SG-190208-A1 (SG)
Title: Methods and compositions for drying coal
Inventor: HARSH PHILIP
Filed: 2010-11-09
Abstract: The present disclosure provides methods, compositions and systems for drying coal fines.
Patent SG-192578-A1 (SG)
Title: An agent for measuring endotoxin
Inventor: MIZUMURA HIKARU
Filed: 2012-02-28
Abstract: A method for rapidly and highly sensitively measuring endotoxin is provided. Endotoxin is measured using an endotoxin-measuring agent comprising the proteins (1) to (3) below, each of which is a recombinant protein obtainable by being expressed using insect cells as a host: (1) a factor C derived from Tachypleus tridentatus, which factor C does not have a His-tag sequence at the C-terminus; (2) a factor B of a horseshoe crab; and (3) a proclotting enzyme of a horseshoe crab.
Patent SG-193012-A1 (SG)
Title: Length-adjustable pressure-retaining piping components
Inventor: WONG HENRY
Filed: 2011-03-02
Abstract: Generally, the subject matter disclosed herein relates to length-adjustable pressure- retaining components used in piping systems. In one illustrative embodiment, a device (10) comprising a first pressure component (1) and an adjustable spacer ring (2) operatively coupled to the first pressure component (1) is disclosed, wherein the adjustable spacer ring (2) is adapted to adjust a combined overall length of said the pressure component and the adjustable spacer ring (2).
Patent SG-193957-A1 (SG)
Title: Composite public cloud, method and system
Inventor: CURRY R STEVEN LYNN
Filed: 2012-05-09
Abstract: A composite public cloud enables an automated marketplace system for, selling and trading of computational resources by aggregating available compute resources so that buyers are automatically matched with sellers. A listing of compute resources available on a prospective seller's system and bids by prospective buyers for resources offered is maintained. A seller uses a series of attributes to characterize an available resource for prospective buyers. Compute resources are presented in a form which can be easily quantified or compartmentalized. Prospective buyers search the marketplace system based on desired resource criteria. The marketplace continually evaluates the attributes of resources available for sale and the desired criteria of prospective buyers. The system attempts to match buyers and sellers, optimizing for the needs of both parties. If a desirable match is found, the marketplace system facilitates a transaction between both parties, making the purchased resource available to the buyer.
Patent WO-2016093769-A1 (WO)
Title: Fil de cuivre (cu) revêtu destiné à des applications de connexion
Inventor: LIAO JIN ZHI
IPC: H01L23/49
Filed: 2015-12-11
Abstract: L'invention concerne un fil et un procédé de fabrication, le fil comprenant au moins un noyau comprenant du cuivre (2) et du phosphore élémentaire ; une première couche de revêtement (3) composée d'au moins un élément choisi dans le groupe comprenant du palladium, du platine et de l'argent ; une couche de revêtement supplémentaire (41) composée d'au moins un élément choisi parmi l'argent et l'or ; au moins une des conditions suivantes étant satisfaite : A1) le rapport de la dimension moyenne des grains des grains cristallins dans le noyau et le diamètre du fil se situe dans la plage allant de 0,14 à 0,28 et le coefficient de variation CV de la dimension moyenne des grains est inférieur à 0,9 ; ou A2) le degré de recristallisation des grains cristallins dans le noyau est dans la plage de 50 à 95 % ; ou A3) la fraction des limites jumelées est dans la plage de 2 à 25 % ; ou A4) de 18 à 42 % des grains du fil sont orientés dans la direction <100> et de 27 à 38 % des grains du fil sont orientés dans la direction <111>.
Patent WO-2015178855-A1 (WO)
Inventor: WONG SHIH JON
IPC: B62L1/00
Filed: 2015-05-20
Abstract: According to one embodiment of the invention, a device for controlling a manual surface maintenance machine is provided. The device attaches to a manual surface maintenance machine and controls the mechanical and electrical components of the manual surface maintenance machine to perform movements from a first location to a next location, while performing surface maintenance operations.
Patent WO-2018208232-A1 (WO)
Title: Attribution de fournisseurs de services et de demandeurs de services en lots dynamiques
Inventor: LYE KONG-WEI
IPC: G06Q50/30
Filed: 2018-05-11
Abstract: L'invention concerne un dispositif processeur comprenant une unité centrale coopérant avec un dispositif d'entrée et un dispositif de sortie, sous la commande d'instructions stockées, et conçu pour recevoir des requêtes de service au niveau du dispositif d'entrée, attribuer des requêtes de service reçues dans des périodes de temps successives à des lots respectifs de requêtes ; accéder à des données de fournisseurs de services stockées pour identifier des fournisseurs de services disponibles parmi un groupe de fournisseurs de services ; après achèvement de l'attribution de requêtes de service à un lot, effectuer un processus de mise en correspondance afin de faire correspondre chaque requête de service du lot de requêtes à un fournisseur de services ; et pour chaque fournisseur de services avec lequel une correspondance est faite, délivrer une notification de la correspondance potentielle respective à partir du dispositif de sortie.
Patent WO-2021126073-A1 (WO)
Title: Membrane electrolysis cell and method of use
Inventor: ZHAO QIPENG
IPC: C25B13/02
Filed: 2019-12-20
Abstract: The present disclosure provides for an electrolytic cell having an electric circuit comprising an anode and a cathode separated by a hydrogel membrane, and an electrolytic system comprising a plurality of the electrolytic cells. The hydrogel membrane may comprise a hydrophilic polymer and acts as an electrolyte. A method of electrolysis, and a method of electrolysis of water, are also disclosed herein. The method may involve locating a hydrogel membrane comprising a hydrophilic polymer between an anode and a cathode of an electric circuit, absorbing liquid into the hydrogel membrane, and passing an electric current through the electric circuit. The liquid may be water. For the method of electrolysis of water, passing the electric current through the electric circuit may be such that the water in the hydrogel membrane is reduced to hydrogen at the cathode and oxygen forms at the anode.
Patent WO-2021045682-A1 (WO)
Title: Colorimetric method for bacteria detection
Inventor: TAN YEN NEE
IPC: B82Y30/00
Filed: 2020-09-01
Abstract: The present invention relates to a colorimetric method for detecting bacterial cells in a sample. The colorimetric method comprises: (a) contacting the sample with nanoparticles to form a mixture, wherein the nanoparticles are characterized by an amorphous core formed from threonine and polyethylenimine; and subsequently (b) contacting the formed mixture with gold nanoparticles, wherein the gold nanoparticles provide a colorimetric indication of the bacterial cells in the sample, depending on the extent of gold nanoparticles aggregation induced by the nanoparticles of (a). In one embodiment, said nanoparticles of (a) are further characterized by a surface functionalised with at least a carbohydrate, such as mannose.
Patent WO-2021256991-A1 (WO)
Title: A light-acoustic system and a method for detecting an anomaly in a structure
Inventor: YAO KUI
IPC: G01N29/04
Filed: 2021-05-31
Abstract: A light-acoustic system and method for detecting an anomaly in a structure are provided. The system includes a light source configured to emit an excitation light and at least one excitation element attached to a surface of a structure. The at least one excitation element includes a photostrictive material and is configured to receive the excitation light for generating an oscillating strain. The oscillating strain generates an acoustic wave in the structure. The system also includes a detector configured to detect the acoustic wave.
Patent WO-2022050895-A1 (WO)
Title: Method and device for managing supply of a geographic area by transport service vehicles
Inventor: BAID ANURAG
IPC: G06Q10/06
Filed: 2021-07-07
Abstract: A method for managing supply of a geographic area by transport service vehicles comprising: determining, for each sub-area, a demand for transport service vehicles, the sum of demand over the sub-areas forming a total demand; determining, a supply of transport service vehicles in the sub-area, the sum over the sub-areas forming a total supply; calculating a first measure as portion of the total demand that can be met with the total supply when demand in a sub-area may be met with supply in a different sub-area; calculating a second measure as portion of the total demand that can be met with the total supply when demand in a sub-area may only be met with supply in the sub-area; calculating a quality of the distribution of the total supply by a ratio of the first and the second measure and managing the supply of the geographic area depending on the quality.
Patent WO-2022169419-A1 (WO)
Title: A method and system for providing an electronic gaming device with online and land-based game play
Inventor: STOUT LOREN
IPC: A63F13/45
Filed: 2022-02-03
Abstract: The present invention is directed to an electronic gaming machine and a method for providing an electronic gaming system as described herein. In general, the present invention provides a system and method for providing an electronic gaming system involving wagering activity that includes both land-based and online wagering and game play. This addresses some of the problems inherent in land-based and physical electronic gaming devices located on a gaming premise by opening up such electronic gaming devices to online remote players.
Patent WO-2019164457-A1 (WO)
Inventor: GÁBORÍK JOZEF
IPC: A63C9/085
Filed: 2019-02-20
Abstract: A front segment of this ski binding, meant to tack the front part of a ski boot, is made from a flat basement (1), fixed arm by its sides (2) and a movable arm (3); on all of these parts there are cone pikes (5) fixed in their upper part, together with a controlling handle (4).
Patent WO-2023277827-A1 (WO)
Title: Structure de conduit d'admission pour un véhicule
Inventor: PISITMANATKUL PASIT
IPC: F02M35/16
Filed: 2021-06-30
Abstract: La présente invention concerne une structure de conduit d'admission (10) pour un véhicule (1) comprenant : un élément de conduit (20) qui est positionné dans un compartiment au moteur (4) et relié à une unité d'admission (5) ; et un couvercle inférieur (50) qui est positionné au-dessous de l'élément de conduit (20) de sorte que de l'air s'écoulant depuis un côté avant du compartiment au moteur (4) se dirige vers l'unité d'admission (5) par l'élément de conduit (20) et le couvercle inférieur (50). L'élément de conduit (20) comprend une première paroi (34) et une seconde paroi (36) qui sont agencées de façon à être dans la même direction vers le bas et parallèles. Le couvercle inférieur (50) comprend une surface descendante (54) qui est agencée de façon à être inclinée vers le bas vers la direction avant et opposée à la première paroi (34) et à la seconde paroi (36).
Patent TN-2010000093-A1 (TN)
Title: Track covering
Inventor: NEUMANN BERNHARD
IPC: E01C9/04
Filed: 2010-02-23
Abstract: Track covering which comprises slab-like covering elements (7) arranged at rail level between the rails (3) of the track (2) and which preferably also comprises slab¬like covering elements (8) adjoining the rails (3) on 'the outside. The covering elements (7, 8) are provided at their edges (10) facing the rails (3) with supporting members (9) which are used to support these covering elements on the rails (3). The supporting members (9) which are arranged on the covering elements (7, 8) at the edges (10) thereof which face the rails (3) are mounted on said covering elements so as to be displaceable in the rail longitudinal direction (11). It is advantageous for at least two supporting members (9) to be arranged displaceably on each edge (10) of the covering elements (7, 8) that faces a rail (3) of the track (2) provided with the covering. Preferably, the supporting members (9) are mounted so as to be displaceable in the rail longitudinal direction (11) and so as to be pivotable about a geometric axis which is parallel to the direction of displacement.
Patent TN-2014000039-A1 (TN)
Title: Dispositif de mesure de la penetration de l'eau sous pression dans le beton sur eprouvettes cylindriques (16/32) et cubiques (15/15/15/)
Inventor: MOUNIR LASMAR DRIDI
IPC: G01M3/26
Filed: 2014-01-24
Abstract: Ce banc d'essai objet d'une propriété industrielle assure le test de pénétration de l'eau sous pression dans le béton. Ce test peut être réalisé au laboratoire sur des éprouvettes ou en chantier sur des canalisations en béton. La nouveauté de ce système se manifeste au niveau de la conception de ce prototype, nous avons rempli presque tous les critères suivants : simple à construire ; peu coûteux ou bon marché ; n'exigeant que du matériel local ou facile à obtenir ; simple à mettre en place ; utilisation et maintenance facile ; ne pas polluer l'environnement ou être nocifs à la santé ; utilisable au laboratoire et au chantier ; pouvant recevoir des éprouvettes cylindriques 16/32 ou celles cubique 15/15/15.
Patent TN-2015000409-A1 (TN)
Title: Rifaximin for use in the treating of vaginal infections
Inventor: VISCOMI GIUSEPPE CLAUDIO
IPC: A61P15/02
Filed: 2015-09-10
Abstract: This invention relates to rifaximin for use in the treatment of bacterial vaginal infections. The invention also relates to the use for treating infections characterized by the presence of bacteria that may be clindamycin and/or metronidazole resistant. The invention also relates to the use of rifaximin to treat patients with vaginal infections who have relapsed following prior treatment or who have bacteria resistant to antibiotics other than rifaximin.
Patent TN-2016000017-A1 (TN)
Title: Piperidinyl indole derivatives and their use as complement factor b inhibitors
Inventor: ADAMS CHRISTOPHER
IPC: C07D417/14
Filed: 2014-07-14
Abstract: The present invention provides a compound of formula I: (I) a method for manufacturing the compounds of the invention, and its therapeutic uses as inhibitors of the complement alternative pathway, in particular of Factor B. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Patent WO-2008060252-A1 (WO)
Title: Système de mise sous tension de panneaux publicitaires
Inventor: KOKAL VAHIT
IPC: G09F11/15
Filed: 2007-10-17
Abstract: L'invention se rapporte à un mode de réalisation consistant en une carcasse (10), de bordures (11) de carcasse constituant ladite carcasse (10), ledit message publicitaire (20) y étant situé et resserré afin de démonter et manutentionner facilement les messages publicitaires (20) sur des emplacements fixes (des panneaux d'affichage), ou bien de manière portative (en particulier sur les deux côtés de véhicules tels que des camions), tout ceci facilement et de manière remplaçable certains intervalles de temps tout en garantissant un positionnement serré du message publicitaire (20).