baber/WOPTO huggingface dataset:
Patent CA-3097585-A1 (CA)
Inventor: DUDEK HENRYK T
IPC: C12N15/63
Filed: 2019-04-01
Abstract: This disclosure relates to oligonucleotides, compositions and methods useful for reducing PCSK9 expression, particularly in hepatocytes. Disclosed oligonucleotides for the reduction of PCSK9 expression may be double- stranded or single- stranded, and may be modified for improved characteristics such as stronger resistance to nucleases and lower immunogenicity. Disclosed oligonucleotides for the reduction of PCSK9 expression may also include targeting ligands to target a particular cell or organ, such as the hepatocytes of the liver, and may be used to treat hypercholesterolemia, atherosclerosis, and/or one or more symptoms or complications thereof.
Patent CA-3097644-A1 (CA)
Inventor: WONG DANIEL
IPC: G06N3/02
Filed: 2020-10-30
Abstract: Une méthode de prévisions de valeurs futures dune variable cible au moyen de valeurs passées connexes est décrite, les valeurs de ladite variable cible étant influencées par une ou plusieurs covariables, indépendantes de la variable cible. La méthode comprend lutilisation dun modèle dintelligence artificielle propre aux covariables pour calculer leffet des covariables sur la variable cible. Leffet des covariables est une modification définie des valeurs de la variable cible entraînée par les covariables. La méthode comprend également le calcul de valeurs passées intrinsèques de la variable cible en éliminant leffet des covariables des valeurs passées de la variable cible. La méthode comprend enfin lutilisation dun modèle dintelligence artificielle propre à la variable cible pour générer une prévision intrinsèque des valeurs futures de la variable cible et calculer une prévision qui comprend leffet des covariables, à laide de la prévision intrinsèque des valeurs futures de la variable cible et de leffet des covariables.
Patent CA-3098828-A1 (CA)
Title: Alfalfa variety afx164041
Inventor: DARLING MARK E
IPC: A23K10/30
Filed: 2020-11-12
Abstract: A novel alfalfa variety designated AFX164041 and seed, plants and plant parts thereof are provided. Methods for producing an alfalfa plant comprise crossing alfalfa variety AFX164041 with another alfalfa plant. Methods for producing an alfalfa plant containing in its genetic material one or more traits transgenes or locus conversions introgressed into AFX164041 through backcross conversion and/or transformation are provided and the alfalfa seed, plant and plant part produced thereby.  Alfalfa seed, plants or plant parts produced by crossing alfalfa variety AFX164041 or a locus or trait conversion of AFX164041 with another alfalfa plant or population are disclosed. Alfalfa populations derived from alfalfa variety AFX164041, methods for producing other alfalfa populations derived from alfalfa variety AFX164041 and the alfalfa populations and their parts derived by the use of those methods.
Patent CA-3099062-A1 (CA)
Title: Systems and methods for deriving information from sampled data on a high-speed data acquisition device
Inventor: MCPHALEN ERIN C
IPC: G06F5/00
Filed: 2020-11-12
Abstract: ABSTRACT A method of deriving information from sampled data, for example, in a digital data stream, includes processing the sampled data, for example, in the high-speed data acquisition device to detect an event in the sampled data. The sampled data is converted/transformed to its first derivative representation, and zero crossing information from the first derivative representation of the sampled data is used to determine local minima and maxima and their relative offset in time to a common point in time. Information from, or derived from, the local minima and maxima and the relative offset are provided to an upstream device. The upstream device may process the local minima and maxima and the relative offset, for example, to characterize the event. Date Recue/Date Received 2020-11-12
Patent CA-3100373-A1 (CA)
Inventor: MILLER BYRD TYLER
IPC: B32B5/12
Filed: 2019-05-15
Abstract: An apparatus for producing endless 3-D printed belts using in papermaking and an apparatus for producing endless 3-D printed belts laminated to a substrate for additional strength and dimensional stability during use.
Patent CA-3103377-A1 (CA)
Inventor: NAGARAJAN HARISH
IPC: C12P7/04
Filed: 2019-06-26
Abstract: Described herein are engineered cells including ones having synthetic methylotrophy which include an NADH-dependent enzyme capable of converting G3P to 3PG (e.g.,6. methanolicus gapN) and/ or fructose-1, 6-bisphosphatase, along with hexulose-6-phosphate synthase, 6-phospho-3-hexuloisomerase, a phosphoketolase, or a combination thereof. Engineered cells of the disclosure beneficially maintain adequate pool sizes of phosphorylated C3 and/or C4 compounds, and/or provide increased levels of NADPH. As such, the modifications allow for the generation of C6 compounds from Cl (e.g. a methanol feedstod) and C5 compounds, the regeneration of C5 compounds from C6 compounds by carbon rearrangement, and an improved balance between regeneration of C5 compounds and lower glycolysis.
Patent CA-3104101-A1 (CA)
Title: Heater
Inventor: LIU TUANFANG
IPC: A24F40/46
Filed: 2020-12-24
Abstract: A heater includes a ceramic core and a metal wire secured to the ceramic core.  The ceramic core includes three through holes.
Patent CA-3104706-A1 (CA)
Inventor: SONI CHIRAG
IPC: G06F3/01
Filed: 2019-10-09
Abstract: System and methods for generating a product recommendation based on reactions such as bio-feedback of a subject during a virtual try-on session are described herein. A recommendation engine captures bio-feedback and determines whether the subject has a positive or negative attitude towards a certain feature of a product that is being virtually "tried on" with the subject. The recommendation engine can then provide a product recommendation based on the actual sentiment of the subject towards a product feature.
Patent CA-3106241-A1 (CA)
Title: Procedes de modification genetique de cellules hematopoietiques
Inventor: BEARD BRIAN
IPC: C12N5/078
Filed: 2019-07-30
Abstract: La présente invention concerne d'une manière générale des procédés de modification génétique de cellules hématopoïétiques. En particulier, l'invention concerne l'utilisation de prostaglandine E2 (PGE2), de poloxamère et de sulfate de protamine pour améliorer la transduction par un vecteur rétroviral recombinant. Les compositions et les procédés de la présente invention sont particulièrement appropriés pour des applications de thérapie génique, comprenant le traitement de maladies et de troubles génétiques monogéniques.
Patent CA-3113854-A1 (CA)
Title: Method and apparatus of encoding or decoding using reference samples determined by predefined criteria
Inventor: LIN ZHI-YI
IPC: H04N19/159
Filed: 2019-10-09
Abstract: A video processing method comprises receiving input data of a current block, checking if the current block satisfies one or more predefined criteria, setting the current block to be a root block if the current block satisfies the predefined criteria, one or more color components of one or more blocks in the current block are not checked with the predefined criteria if the current block is a root block, encoding or decoding the one or more color components of one or more blocks in the current block using neighboring reconstructed samples of the one or more color components of the current block as reference samples if the current block is a root block. Each block in the current block is encoded or decoded using neighboring reconstructed samples of each block in the current block as reference samples if the current block is not a root block.
Patent CA-3114929-A1 (CA)
Title: Recipient de poudre et appareil de formation d'image
Inventor: HOSOKAWA HIROSHI
IPC: G03G21/18
Filed: 2014-03-14
Abstract: 88134783 ABRÉGÉ : Il est décrit un réservoir à poudre contient de la poudre utilisée afin de former une image et doit être fixé à un appareil de formation dimages. Lappareil de formation dimages comprend les éléments suivants : une buse de transport pour transporter la poudre; un orifice de réception de poudre qui est prévu sur la buse de transport et reçoit la poudre du réservoir à poudre; un engrenage du corps principal de lappareil pour transmettre une force dentraînement au réservoir à poudre; et une partie de réception de réservoir qui est disposée autour de la buse de transport et accueille le réservoir à poudre. Le réservoir à poudre comprend ce qui suit : une ouverture qui est prévue sur une extrémité du réservoir à poudre dans le sens longitudinal; un récepteur de buse qui est disposé dans louverture et accueille la buse de transport; un convoyeur rotatif qui tourne pour transporter la poudre vers lorifice de réception de poudre; et un engrenage de réservoir qui est prévu près de louverture et entraîne le convoyeur en sengrenant avec lengrenage du corps principal de lappareil. Lengrenage du réservoir est disposé de manière à sengrener avec lengrenage du corps principal de lappareil à une position plus proche de louverture que de lorifice de réception de la poudre dans le sens longitudinal. Louverture doit se coupler à la partie de réception du réservoir. Date reçue/Date Received 2021-04-13
Patent CA-3117341-A1 (CA)
Inventor: SOLLENBERGER EDWARD D
IPC: B29C45/26
Filed: 2019-10-25
Abstract: A polymer injection-molding mold having a polymer injection-molding mold having a core insert and a cavity insert; at least two rear-wall glass-filled polyimide insulation plates, at least two side-wall glass-filled polyimide insulation plates, a plurality of substantially cylindrical fluid-cooling channels that are respectively positioned within the cavity insert and core insert; and a temperature-sensing thermocouple that is located within the cavity insert or core insert in a position that is substantially adjacent to an estimated last volume of space to be filled by polymer-mold flow.
Patent CA-3117385-A1 (CA)
Title: Siliconaluminophosphate molecular sieve, its preparation and application thereof
Inventor: YANG WEIMIN
IPC: B01J27/00
Filed: 2019-09-19
Abstract: Provided are a novel silicon-phospho-aluminum molecular sieve, preparation method and application thereof. The molecular sieve has a schematic chemical composition in molar ratio mSiO 2·Al 2O 3·nP 2O 5, wherein m represents the ratio of silicon to aluminum and is in the range of about 0.005-0.15, and n represents the ratio of phosphorus to aluminum, and is in the range of about 0.7-1.1. The preparation method thereof comprises mixing a silicon source, an aluminum source, a phosphorus source, an organic substance R and water in proportion to obtain a synthetic mother liquor; crystallizing the synthetic mother liquor to obtain a molecular sieve precursor; calcining the precursor to obtain a molecular sieve. The molecular sieve has a unique X-ray diffraction pattern and can be used as an adsorbent, a catalyst or a catalyst support.
Patent CA-3121123-A1 (CA)
Title: Implantable reservoir for use with a medical device and system for interventional drug delivery
Inventor: DAUNCH WILLIAM
IPC: A61N1/30
Filed: 2019-11-25
Abstract: A surgically implantable reservoir is provided for implantation into a patient for use in an iontophoresis system for local drug delivery through a target site of internal body tissue. The reservoir comprises a housing having an inner surface defining an enclosed chamber and an inlet opening and an outlet opening for flow of fluid including the drug through the chamber. The housing is capable of interacting with a localized electric field to release the drug. A platform holding an electrode extends inwardly into the chamber from the inner surface of the housing such that the platform and an adjacent portion of the inner surface of the housing define a trough surrounding the platform. Fluid flow through the reservoir from the inlet opening to the outlet opening moves gas bubbles formed by electrolysis from the surface of the electrode and carries the bubbles through the outlet opening.
Patent CA-3122825-A1 (CA)
Title: Process for producing ultrahigh molecular weight polymer in powder form
Inventor: KAUR SUKHDEEP
IPC: C08F10/08
Filed: 2021-06-21
Abstract: The present invention relates to a process for producing ultrahigh molecular weight polymer in powder fonn which is highly efficient drag reducing polymer. The process consists of polymerizing using titanium halide-based catalyst, co-catalyst, optionally a solvent, and monomer to a polymerization reactor, having stirring device and inlet charging and discharge outlet. The resulting ultrahigh molecular weight drag reducing polymers is free flowing, having intrinsic viscosity > 10 dL/g. The process reduces polymerization time, temperature, and achieves high conversion, i.e., > 90%.
Patent CA-3123360-A1 (CA)
Title: Methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate active compound product having improved properties, production and formulation thereof
Inventor: FEY PETER
IPC: C07D471/04
Filed: 2019-12-16
Abstract: The present invention relates to methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4- b]pyridin-3-yl]pyrimidin-5-yl}carbamate in the form of a novel active compound product having improved properties, for example in respect of the isolability of the active compound product, the dischargeability of the active compound product after isolation and drying and also conveyability, sieveability and micronizability of the active compound product, and to processes for the production and formulation thereof.
Patent CA-3124278-A1 (CA)
Title: Cream-cheese-like food product and production method
Inventor: MAHLER MARIE-LUISE
IPC: A23C20/02
Filed: 2019-12-17
Abstract: The invention relates to a method for producing a cream-cheese-like, preferably vegan, food product with a strength measured at 10°C by a texture testing machine, in which a round press plunger with a surface area of 1.27cm and a speed of 2mm/s is introduced into a sample, said strength coming from a value range between 0.2 N and 7.0 N, preferably between 0.5 N and 2.5 N, a dry mass weight proportion between 6% and 80% and a total fat weight proportion between 0.92% and 30%, comprising the following steps: producing a pumpable mass based on water and nuts and/or seeds, preferably almonds; and obtaining the food product from the pumpable mass. The invention is characterised in that the pumpable mass is produced by mixing a partially de-oiled flour made from the nuts and/or seeds, preferably almond flour, having a fat weight proportion between 5 and 20 wt.%, with the water and fat, in particular in the form of oil.
Patent CA-3125988-A1 (CA)
Inventor: FRID EUGENE
IPC: B81B7/02
Filed: 2019-11-14
Abstract: L'invention concerne un dispositif électrique tel que, par exemple, un verrouillage mécanique comprenant un ou plusieurs composants électriques interconnectés configurés pour détecter ou surveiller un état de fonctionnement. Dans un mode de réalisation, le dispositif électrique peut comprendre un bus de communication, un ou plusieurs modules de capteur couplés au bus de communication, et un module concentrateur de capteur couplé au bus de communication, le ou les modules de capteur générant un ou plusieurs signaux comprenant des données indiquant un état détecté. Un module de communication couplé au module concentrateur de capteurs peut transmettre les données indiquant l'état détecté à un dispositif à distance, à un réseau informatique à distance, ou à un service en nuage à distance. En outre, et/ou en variante, le dispositif peut comprendre un capteur de détection d'eau comprenant des première et seconde traces conductrices incurvées. En outre, et/ou en variante, le dispositif peut comprendre un circuit limiteur de tension fournissant une tension de sortie CC à partir d'une entrée CA haute tension.
Patent CA-3127177-A1 (CA)
Inventor: NAKAHIGASHI KENJI
IPC: C12N15/90
Filed: 2020-01-30
Abstract: La présente invention concerne un procédé de production d'une protéine de recombinaison, ledit procédé comprenant: une étape de réduction de la prolifération permettant de réduire la prolifération cellulaire de cellules de recombinaison exprimant la protéine de recombinaison; et une étape de production permettant de réaliser une culture de cellules de recombinaison, lesdites cellules de recombinaison étant dans un état de prolifération cellulaire réduite, dans un milieu de production de protéines pour ainsi produire une protéine de recombinaison, dans l'étape de réduction de prolifération, la prolifération cellulaire des cellules de recombinaison étant réduite en utilisant, en tant que cellules de recombinaison, des cellules de recombinaison contenant au moins un régulateur de morphogenèse modifié.
Patent CA-3127869-A1 (CA)
Title: Air purifier
Inventor: D'ANDREA ALESSIO
IPC: F24F8/175
Filed: 2020-01-31
Abstract: An air purifier is disclosed which includes a first pot (22, 14); a second pot (24) and (c) a fan (4) suitable for creating an air flow between the inside and outside of the air purifier. The second pot (24) which is provided with a bottom (15) and is housed inside the first pot in which the lateral walls of the second pot are formed by a plurality of ribs (24a) which extend in the vertical direction of the pot (24) and in which adjacent ribs are arranged essentially parallel to each other, creating slots between them essentially of the length of the ribs (24a). A gap (30) is formed between the first pot and the second pot (24) which extends preferably along the entire length of said slots. The invention also relates to a relative use of the air purifier.
Patent CA-3128028-A1 (CA)
Title: Predicting three-dimensional features for autonomous driving
Inventor: ELLUSWAMY ASHOK KUMAR
IPC: G06V10/764
Filed: 2020-01-28
Abstract: A processor coupled to memory is configured to receive image data based on an image captured by a camera of a vehicle. The image data is used as a basis of an input to a trained machine learning model trained to predict a three-dimensional trajectory of a machine learning feature. The three-dimensional trajectory of the machine learning feature is provided for automatically controlling the vehicle.
Patent CA-3129444-A1 (CA)
Inventor: YAKHNICH VLAD
IPC: A61B5/151
Filed: 2020-02-11
Abstract: L'invention concerne un dispositif destiné à obtenir un échantillon de sang, le dispositif comprenant un support pour recevoir une source d'échantillon, le support ayant une partie d'actionnement et un orifice, une partie de mise en prise de récipient reliée au support, et un récipient de collecte pouvant être relié amovible à la partie de mise en prise de récipient, le récipient définissant une cavité de collecte, la partie de mise en prise de récipient permettant au récipient de collecte de tourner entre une première position dans laquelle le récipient de collecte est espacé de l'orifice et une seconde position dans laquelle le récipient de collecte est en communication fluidique avec l'orifice.
Patent CA-3133041-A1 (CA)
Title: Methodes de diagnostic du cancer du poumon
Inventor: SOUCEK LAURA
IPC: A61K51/08
Filed: 2020-03-19
Abstract: L'invention concerne les utilisations diagnostiques d'un conjugué comprenant de l'Omomyc ou un variant fonctionnellement équivalent de celui-ci et une étiquette détectable pour détecter un cancer du poumon par administration pulmonaire du conjugué. L'invention concerne également un procédé de détection ou d'imagerie du cancer du poumon utilisant lesdits conjugués, des kits comprenant lesdits conjugués et des conjugués comprenant un agent de contraste ou un agent d'imagerie.
Patent CA-3133164-A1 (CA)
Inventor: SCHLIEPER JORG
IPC: A61C9/00
Filed: 2020-03-09
Abstract: The invention relates to a device (4) for detecting jaw relation data of a person, comprising a first elongated jaw relation element (6) which extends in a ventral direction when installed on the person and which is configured to be secured to an upper jaw bearing element (5); a second elongated jaw relation element (7) which extends in a transversal and caudal direction relative to the first jaw relation element (6); and a third elongated jaw relation element (8) which extends in the transverse and dorsal direction relative to the second jaw relation element (7). The second jaw relation element (7) is movably connected to the first jaw relation element (6) in the extension direction of the second jaw relation element, and/or the third jaw relation element (8) is movably connected to the second jaw relation element (7) in the extension direction of the third jaw relation element such that the second or third jaw relation element (8) is configured so as to be supported on at least one incisal or occlusal surface of one or more lower jaw tooth crowns and/or so as to be arranged at a distance from the lower jaw tooth crowns in a capturable manner together with the lower jaw tooth crowns by a digital capturing device. The invention also relates to a method for detecting jaw relation data of a person using a device (4) according to one of the aforementioned claims and using a scanner. At least two markings (200) are provided on the upper jaw bearing element (5) in the region bordering tooth crowns and/or tooth crown portions and at least on the first to third jaw relation element (6; 7; 8), said markings being detected by the scanner so as to uniquely detect positions of the jaw relation elements (6; 7; 8) in order to ascertain jaw relation positions.
Patent CA-3133729-A1 (CA)
Inventor: CASTIGLIONE GIUSEPPE MARCELLO ANTONIO
IPC: G06N20/00
Filed: 2021-10-08
Abstract: Systems and methods for diagnosing and testing fairness of machine learning models based on detecting individual violations of group definitions of fairness, via adversarial attacks that aim to perturb model inputs to generate individual violations.  The systems and methods employ auxiliary machine learning models using a local surrogate for identifying group membership and assess fairness by measuring the transferability of attacks from this model. The systems and methods generate fairness indicator values indicative of discrimination risk due to the target predictions generated by the machine learning model, by comparing gradients of the machine learning model to gradients of an auxiliary machine learning model.
Patent CA-3134159-A1 (CA)
Inventor: ADAMCZAK LOIC
IPC: F16D65/00
Filed: 2020-03-27
Abstract: The invention relates to a braking system comprising a brake pad (10), the pad comprising a base (1) with a first face (13) and a second face (14), and a lining (2) that is made of friction material and is secured to the first face (13), the lining (2) being delimited by a friction face (26), a mounting face (20), an inner edge (23), an outer edge (24), a rear edge (21) and a front edge (22), the lining (2) being provided with at least one collecting groove (3) which is open on the friction face (26), extends to the inner edge (23) at its first end (31), and runs to the outer edge (24) at its second end (32). The braking system further comprises a collecting system which comprises a collecting pipe (40) through which air can flow, the air inlet port (41) of the collecting pipe (40) facing the second end (32), and the collecting groove (3) opening into the outer edge (24) at its second end (32).
Patent CA-3139188-A1 (CA)
Title: Ball valve
Inventor: REID MICHAEL ADAM
IPC: F16K5/06
Filed: 2019-07-31
Abstract: A ball valve stopper comprising a spherical contoured body comprising a substantially inelastic first material and having a flow port. A closed face of the spherical contoured body is orthogonal with respect to the flow port and includes a spherical fluid seal area. A rotation support member is aligned orthogonally to the flow port and the fluid seal area. A material discontinuity volume is disposed behind the closed face of the spherical contoured body.