baber/WOPTO huggingface dataset:
Patent CA-2915296-A1 (CA)
Title: Structure, manufacturing and uses of human-derived cell-permeable peptides conjugated with specific biologically active cargo peptides
Inventor: LITTMAN BRUCE H
IPC: A61K47/48
Filed: 2014-06-11
Abstract: Embodiments disclosed herein provide compositions for conjugates, including fusion proteins, and methods of using them to treat a variety of conditions. In some embodiments, the conjugates and/or fusion proteins incorporate a 60-amino acid human homeodomain (e.g., peptides derived from human HOX genes), to translocate functional and regulatory peptides and proteins or other biologically active molecules such as nucleic acids, which are not naturally associated with the human homeodomain, across cell and nuclear membranes to intended sites of action without provoking an unwanted immune response that may reduce exposure to the conjugate and/or result in a clinical adverse event. In further embodiments, disclosed conjugates and fusion proteins can pass through the blood-brain barrier to allow entry into the CNS. In various embodiments, the disclosed compositions are suitable for delivery into a cell (i) the expression product of a gene of interest and/or (ii) novel peptides or polynucleotides to regulate gene function.
Patent CA-2915654-A1 (CA)
Inventor: MARINO KENNETH D
IPC: B23K1/00
Filed: 2015-12-17
Abstract: An intelligent soldering cartridge that includes: a housing; a solder tip; a heater for heating the solder tip; a storage device for storing information about characteristics of the cartridge; a processor for retrieving the information about characteristics of the cartridge, monitoring the power level delivered to the solder tip to detect liquidus occurrence at a solder joint, determining a thickness of an intermetallic compound (IMC) of the solder joint using some of the retrieved information, determining whether the thickness of the IMC is within a predetermined range, and generating an indication signal indicating that a reliable solder joint connection is formed when the thickness of the IMC is within the predetermined range; and an interface for transmitting the indication signal.
Patent CA-2916028-A1 (CA)
Inventor: TICHO BARRY
IPC: C07K16/28
Filed: 2014-07-03
Abstract: The invention relates, inter alia, to methods of treating stroke, e.g., ischemic stroke, e.g., acute ischemic stroke, and methods of reducing infarct size and/or other neurological deficits associated with stroke, e.g., ischemic stroke, e.g., acute ischemic stroke, using a VLA-4 antagonist such as natalizumab. It was discovered that VLA-4 antagonists such as natalizumab can effectively reduce the infarct size and other associated neurological deficits of a stroke, e.g., an ischemic stroke; e.g., an acute ischemic stroke, e.g., when administered within a specified time period after the onset of the stroke. Also disclosed herein are articles of manufacture and kits for the treatment of stroke, e.g., ischemic stroke, e.g., acute ischemic stroke.
Patent CA-2916265-A1 (CA)
Inventor: PARAKH VISHAL
IPC: G06Q10/06
Filed: 2014-06-24
Abstract: Processes and systems are disclosed for leasing a producer virtual machine on behalf of a consumer virtual machine in an overlay network. The consumer host of the consumer virtual machine can communicate with a set of leasing agents to obtain the identity of a number of producer virtual machines capable of providing the consumer virtual machine with access to a service.  When the consumer virtual machine attempts to communicate with a producer system, the consumer host can identify a producer host that hosts a target producer virtual machine and redirect a service request to the producer host.
Patent CA-2917002-A1 (CA)
Inventor: SINHA RAHUL
IPC: H04W4/02
Filed: 2014-06-23
Abstract: A method and system for validating presence of a communication device in a confined area using a wireless local area network (WLAN) includes sending a first handshake message including a generated first key over a second network connection different from the WLAN connection by a device. A next step includes generating a second key to be returned to the device in a second handshake message over the same connection. A next step includes sending a WLAN probe request that has been modified to include the second key via the WLAN. A next step includes validating whether the device is present within the confined area using a second communication network; whereafter allowing communication access over the second network using both the first and second keys if the device is validated as being present within the confined area, and taking appropriate action if the device is not validated as being present within the confined area.
Patent CA-2917379-A1 (CA)
Inventor: GE HONG
IPC: G06Q30/08
Filed: 2014-08-05
Abstract: A social networking system prices advertisements presented to a user of a social networking system via a client device in a state that provides the user with limited functionality by applying discount factors to bid amounts associated with advertisements selected for presentation. A discount factor is based on the likelihood of the user viewing or interacting with an advertisement via the social networking system presented while the client device is in the state providing the user with limited functionality. This likelihood is determined based on information including a history of user interaction with the client device and contextual information indicating whether the client device is in use.
Patent CA-2917791-A1 (CA)
Inventor: LIU JANE
IPC: A01N43/653
Filed: 2014-07-10
Abstract: The present invention relates to non-aqueous pesticidal dispersible concentrate formulations comprising from about 2 to about 10 % of at least one pesticidal agent, from about 15 to about 25 % of hexylene glycol, from about 65 to about 75 % of propylene glycol, a hydrophobic silica, and a surfactant, wherein the weight percentages are based on the total weight of the formulation. Formulations of the present invention have superior storage stability but are non-phytotoxic to seeds when used as a seed treatment. The present invention also relates to ready-to-use products made from the concentrated formulations of the present invention. Further, the present invention includes methods of using the pesticidal dispersible concentrate formulations and ready-to-use products to achieve superior plant protection and disease control.
Patent CA-2918471-A1 (CA)
Title: Pressure compensated glass unit
Inventor: CLARAHAN GREGORY L
IPC: E06B3/667
Filed: 2014-07-18
Abstract: A glass unit including a spacer, a front glass pane attached to a front side of the spacer, a back glass pane attached to a back side of the spacer, and a pressure equalization conduit defined by and within the spacer, wherein the pressure equalization conduit has a first end and a second end, wherein the pressure equalization conduit contains a desiccant and is in fluid communication with an exterior of the glass unit at a first end port adjacent to the first end and with an interior space of the glass unit at a second end port adjacent to the second end. The glass unit may further include one or more intermediate layers contained within the interior space and one or more floating suspension systems for supporting the intermediate layers.
Patent CA-2918985-A1 (CA)
Title: Resin composition, injection material and packing method
Inventor: MAEDA FUMIHIRO
IPC: C08K5/42
Filed: 2014-07-23
Abstract: This resin composition is used in order to form surface layers which coat at least portions of outer surfaces of particles used to fill fractures formed in a subterranean layer, and includes: an acid curing agent provided with acidic groups; an acid curable resin which cures in the presence of an acid; and polyester. The acid curing agent is present in a state in which the acidic groups therein are blocked by a compound exhibiting reactivity with the acidic groups. As a result, a resin composition with which an acid curable resin can be reliably cured in a desired place, an injection agent including said resin composition and particles, and a filling method using said particles to fill fractures formed underground can be provided.
Patent CA-2920307-A1 (CA)
Inventor: HUGH KEVIN A
IPC: B01L7/00
Filed: 2016-02-09
Abstract: Provided are a cannabis composition in pellet form, a method of preparing a cannabis composition in pellet form, a method of separating a plant resin from a harvested plant material, a method of treatment with a cannabis composition in pellet form, and a kit including a cannabis composition in pellet form. For example, the cannabis composition in pellet form may include a cannabinoid resin. The cannabinoid resin may include one or more of: a tetrahydrocannabinol extract and a cannabidiol extract.
Patent CA-2921043-A1 (CA)
Title: Copolymeres de polyacrylamide glyoxalate de grande masse moleculaire et de grande charge cationique et methodes de fabrication et d'utilisation
Inventor: WRIGHT MATTHEW D
IPC: D21H17/49
Filed: 2014-09-08
Abstract: L'invention concerne une composition de copolymères de polyacrylamide à glyoxalate, ses procédés de production et son utilisation, par exemple, pour renforcer le papier ou le carton. La composition de copolymères de polyacrylamide à glyoxalate comprend un milieu aqueux contenant un copolymère à glyoxalate, ledit copolymère à glyoxalate étant obtenu en faisant réagir un milieu réactionnel aqueux d'un certain rapport en poids sec de copolymère de glyoxal cationique. Le copolymère cationique peut avoir un poids moléculaire moyen d'environ 120 000 à environ 1 million de Daltons, il peut comporter un monomère d'halogénure de diallyl-diméthyl-ammonium et un monomère d'acrylamide, et un rapport poids moléculaire moyen du copolymère cationique avant glyoxalation sur % en poids du monomère d'halogénure de diallyl-diméthyl-ammonium constituant le copolymère cationique avant glyoxalation égal ou supérieur à 4 000 ou compris entre 4 000 et 40 000 Daltons/% en poids.
Patent CA-2928127-A1 (CA)
Inventor: PLASSON FABRICE
IPC: A01N63/00
Filed: 2014-10-22
Abstract: The invention relates to a process for combating the proliferation of the Naegleria genus and in particular of the species Naegleria fowleri, with the exception of the treatment methods applied to the human or animal body, characterized in that it uses protozoa of the species Willaertia magna, and also a disinfecting agent containing such protozoa.
Patent CA-2930596-A1 (CA)
Inventor: ALSINA-FERNANDEZ JORGE
IPC: C07K14/605
Filed: 2014-12-11
Abstract: The present invention provides a novel compound useful in the treatment of hypoglycemia.
Patent CA-2931035-A1 (CA)
Title: Appareil de tondeuse de vegetation a avance directe
Inventor: ALLISS GEORGE E
IPC: A01D34/416
Filed: 2014-11-20
Abstract: L'invention concerne une tête de tondeuse destinée à être utilisée avec des têtes de tondeuse à rotation dans le sens des aiguilles d'une montre ou dans le sens inverse des aiguilles d'une montre, comprenant l'utilisation d'un rouleau de distribution bidirectionnelle. Divers emplacements de passages directement à travers la tête de tondeuse et le rouleau sont présentés conjointement avec divers emplacements d'éléments du mécanisme d'encliquetage pour permettre l'enroulement du fil de coupe sur la tête de tondeuse et pour limiter la quantité de fil de coupe distribué pendant la « frappe » du bouton de tête de tondeuse sur le sol. En raison de l'agencement minutieux des éléments, la tête de tondeuse peut avoir un fil de coupe enroulé dans une seule direction sur le rouleau et distribuer encore du fil de coupe indépendamment de la direction dans laquelle tourne la tête de tondeuse, en accélérant ou en ralentissant le rouleau par rapport au boîtier de tête de tondeuse pour permettre au fil de coupe d'être distribué indépendamment de la direction de rotation de l'arbre d'entraînement de machine de tondeuse faisant tourner la tête de tondeuse.
Patent CA-2933415-A1 (CA)
Title: Confined linear detection and location method and device
Inventor: DELAVEAU FRANCOIS
IPC: H01Q13/20
Filed: 2014-12-10
Abstract: Device and method for confined detection and location of one or more radio devices (4) that are present in a closed or semi-open prohibited zone, characterized in that said device comprises at least the following elements: a linear aerial (1) comprising several orifices Oi suitable for capturing signals emitted by the prohibited radio device or devices and subsequent transmission thereof via the linear aerial to a receiving device (2) linked to the linear aerial (1) via a connector (3), the receiving device being suitable for processing the signals captured by the linear aerial (1) in order to detect the presence of prohibited devices in said zone and to reject detections of authorised devices outside of the said zone.
Patent CA-2935117-A1 (CA)
Inventor: LINARES MIGUEL A
IPC: B31D5/00
Filed: 2015-01-09
Abstract: An assembly and associated method for constructing a three dimensional article, such as a pallet, including a first station for feeding a sheet material in blank form, a second a second station for receiving and incising the blank, a third station for receiving the incised blank and which successively creases and folds the blank into an assembled article, and a fourth operator station for controlling each of said first, second and third stations. Also disclosed is a conveyor for removing the assembled article from the third station and transferring to a plastic coating operation.
Patent CA-2935281-A1 (CA)
Inventor: SCRIFFIGNANO ANTHONY J
IPC: G06F15/18
Filed: 2014-12-23
Abstract: A multidimensional recursive and self-perfecting process used to discover dyadic or multi-counterparty relationships between parties, the process comprising: (a) collecting information from a plurality of data sources; (b) discovering dyadic or multi-counterparty relationships between the parties from the collected information; (c) clustering the parties to infer the dyadic or multi-counterparty relationships between the parties based on common or partially intersecting attributes between the parties, thereby forming clustered parties; (d) evaluating the clustered parties for business linkage potential by integrating the collected information and contextually assessing indicia from the data sources to detect and measure consistency and inconsistency for a given party or dyadic or multi-counterparty relationship; (e) positing and evaluating relationship type and role said party plays in each relationship; and (t) assessing the confidence level regarding the likelihood that the dyadic or multi-counterparty relationship exists between the parties.
Patent CA-2935516-A1 (CA)
Inventor: GARNER CRAIG C
IPC: A61P25/28
Filed: 2007-05-22
Abstract: Methods for treating an individual to improve cognitive function are provided.  In the subject methods, an effective amount of a noncompetitive GABA A ionophore blocker is administered to the individual, resulting in an improvement in cognitive function of the host.  The subject methods find use in a variety of different applications.
Patent CA-2936035-A1 (CA)
Inventor: TOMS MATTHEW JASON
IPC: E03F5/04
Filed: 2013-12-24
Abstract: A height-adjustable assembly for a drain, comprises a lower portion (401) for use with a waste outlet of the drain, an upper portion (403) to receive an attachment (407) for mounting at floor level to cover the assembly, and an adjustment portion (405) disposed between the upper and lower portions and including first and second adjustment elements (420, 425) disposed respectively on inner and outer faces of the adjustment portion to simultaneously vary the position of the upper and adjustment portions relative to the lower portion as the adjustment portion is rotated. The first adjustment element is a ramp which cooperates with a ramp follower (421) on the upper portion whereas the second adjustment element is a protrusion which cooperates with a further ramp (427) on the lower portion.
Patent CA-2938184-A1 (CA)
Inventor: TAKAHASHI TAKUYA
IPC: A61P25/28
Filed: 2015-01-30
Abstract: Provided is a medicinal composition characterized by comprising an alkyl ether derivative represented by general formula [1] [wherein: R1 and R2 are the same or different and represent a hydrogen atom, a halogen atom, an optionally substituted C1-6 alkyl group, an optionally substituted aryl group, etc.; R3 represents an optionally protected hydroxyl group, etc.; and m and n are the same or different and represent an integer of 1 to 6] or a salt thereof. The medicinal composition according to the present invention is useful as a post nerve injury rehabilitation effect-enhancing agent.
Patent CA-2938871-A1 (CA)
Title: Gust alleviator
Inventor: RICHARDSON ALBERT S JR
IPC: B64C21/02
Filed: 2015-02-03
Abstract: A gust alleviating aircraft wing includes a gust alleviating wing portion on the wing. The wing portion can have a leading edge, a trailing edge, and a downwardly sloping upper surface therebetween. At least one air passageway can extend through the wing portion from the leading edge to a rear or downstream location on the downwardly sloping upper surface of the wing portion. At least one spoiler can be on the upper surface of the wing portion at the rear location for selectively movably covering and uncovering an exit location of the at least one passageway. Opening the at least one passageway is capable of diverting air flow through the at least one passageway and the wing portion for counteracting upward lift caused by a gust of wind.
Patent CA-2939033-A1 (CA)
Inventor: GARNER ANDREW
IPC: C09K21/04
Filed: 2014-02-06
Abstract: La présente invention concerne une composition ignifugeante à base de polyphosphate d'ammonium comprenant un polyphosphate d'ammonium, un agent de suspension, et une quantité efficace d'au moins deux agents d'inhibition de la corrosion choisis dans le groupe constitué par des agents d'inhibition de la corrosion comprenant du charbon actif, des sels d'Epsom, du gypse, des azoles, et des inhibiteurs en phase vapeur. Ladite composition peut en outre comprendre une gomme de xanthane, un agent colorant ou les deux.
Patent CA-2942113-A1 (CA)
Inventor: POIROT LAURENT
IPC: C12N5/0783
Filed: 2015-03-11
Abstract: A method for preparing an engineered T-cell is described, comprising the steps of a) inhibiting the expression of beta 2-microglobulin (B2M) and/or class II major histocompatibility complex transactivator (CIITA) in a T-cell that has been provided; b) inactivating at least one gene encoding a component of the T-cell receptor (TCR) in said T-cell; and c) introducing into said T-cell an exogenous nucleic acid molecule comprising a nucleotide sequence coding for a Chimeric Antigen Receptor (CAR) directed against at least one antigen expressed at the surface of a malignant or infected cell. The engineered isolated T-cell expresses a CAR  directed against at least one antigen expressed at the surface of a malignant or infected cell, in which i) the expression of B2M and/or CIITA is inhibited; and ii) at least one gene encoding a component of the TCR is inactivated.
Patent CA-2942323-A1 (CA)
Inventor: BREEDEN WINSTON H III
IPC: B65G69/28
Filed: 2016-09-19
Abstract: Provided is a loading ramp having first and second ramp portions coupled by a hinge assembly such that the first and second ramp portions are movable relative to one another between an extended position and a folded position.  The loading ramp also has one or more lights coupled to one of the ramp portions and a switch assembly coupled to the ramp portions such that in the extend position the switch assembly is activated to illuminate the one or more lights.
Patent CA-2943142-A1 (CA)
Title: Basestock production from feeds containing solvent extracts
Inventor: VAUGHN NICOLE D
IPC: C10G65/04
Filed: 2015-02-27
Abstract: Methods are provided for producing Group II / III lubricant base oil products where at least a portion of the feedstock for forming the lubricant base oil product is a solvent extract fraction from a Group I lubricant production facility. This can increase the overall volume of feedstock available for production of Group II / III lubricant base oils by using a lower value stream (Group I solvent extract) as a portion of the feedstock. The solvent extract fraction can be added to a full range lubricant feedstock or to a portion of a lubricant feedstock, such as adding an extract fraction to a higher viscosity portion (such as a heavy neutral portion) of a feedstock for lubricant production, while a lower viscosity portion (such as a light neutral portion) is processed without addition of an extract fraction.
Patent CA-2946552-A1 (CA)
Inventor: MORGAN RICHARD
IPC: C12N5/0783
Filed: 2015-04-24
Abstract: The invention provides compositions and methods for manufacturing adoptive cell therapies. In particular embodiments, the invention provides methods of harvesting populations of cells, isolating and activating PBMCs, expanding T cells, and administering the T cell therapeutic to a subject in need thereof.
Patent CA-2946791-A1 (CA)
Title: Catheter and catheter system for electrical neuromodulation
Inventor: GOEDEKE STEVEN D
IPC: A61M25/10
Filed: 2015-05-21
Abstract: A catheter having an elongate body, at least two elongate stimulation members extending from the elongate body, at least one electrode on each of the elongate stimulation members, where the electrodes form an electrode array that receives and conducts electrical current. The elongate stimulation members curve only in the first volume defined at least in part by a first plane, and a second volume defined at least in part by the first plane and being opposite the first volume can contain no electrodes. The catheter can further include a position gauge having a marking that indicates a length between a second end of the elongate body and a bumper end of the position gauge. The catheter can also include a pulmonary artery catheter having a lumen, where the catheter extends through the lumen of the pulmonary artery catheter.
Patent CA-2947529-A1 (CA)
Inventor: TANIGUCHI SHUN-ICHIRO
IPC: A61K39/395
Filed: 2015-04-17
Abstract: The present invention addresses the problem of providing signal sequence information that makes it possible for an antibody to be secreted extracellularly in antibody production by microorganisms of the genus Bifidobacterium and an antibody expression vector that makes it possible for an antibody to be secreted extracellularly using this signal sequence information. The present invention overcomes this problem by preparing Bifidobacterium longum transformed by a vector having a DNA insert, linked to the 5' terminus of the antibody gene, inserted at the 3' terminus of DNA encoding a signal peptide-linker linked body that has a linker linked to the C terminus of a signal peptide comprising an amino acid sequence shown in SEQ ID NO.: 1.
Patent CA-2948951-A1 (CA)
Title: Synthese d'acides nucleiques bicatenaires
Inventor: TURCHINOVICH ANDREY
IPC: C12N15/11
Filed: 2015-05-15
Abstract: La présente invention concerne un procédé pour la synthèse d'acides nucléiques bicaténaires à partir d'une large variété d'échantillons et comprend l'utilisation de ces acides nucléiques pour une analyse approfondie des séquences. De plus, la présente invention concerne des réactifs spécifiques utilisés dans le procédé de la présente invention. En outre, l'invention concerne des kits comprenant des réactifs pour le procédé de l'invention et l'utilisation desdits kits.