baber/WOPTO huggingface dataset:
Patent CA-3124228-A1 (CA)
Title: Non-human animals that make single domain binding proteins
Inventor: GURER CAGAN
IPC: C12P21/08
Filed: 2015-03-20
Abstract: Genetically modified non-human animals and methods and compositions for making and using them are provided, wherein the genetic modification comprises (a) a deletion in an immunoglobulin constant region CH1 gene (optionally a deletion in a hinge region) of a heavy chain constant region gene sequence, and (b) replacement of one or all endogenous VH, DH and JH gene segments with at least one unrearranged light chain variable (VL) gene segment and at least one unrearranged light chain joining (JL) gene segment capable of recombining to form a rearranged light chain variable region (VL/JL) nucleotide sequence operably linked to the heavy chain constant region gene sequence comprising a deletion in the CH1 gene and/or insertion of a genetically engineered single rearranged light chain, wherein the mouse is capable of expressing a functional lgM, single domain antigen binding proteins, e.g., VL-single domain binding proteins, and a genetically engineered rearranged light chain.
Patent CA-3125113-A1 (CA)
Inventor: KOCH BERNHARD
IPC: E01B29/28
Filed: 2021-07-20
Abstract: A track processing machine, in particular an impact wrench machine for track processing, comprises at lcast one handle for manually guiding thc track processing machine, a first structural unit with a processing head, which can be driven in rotation for track processing about an axis of rota-tion, a second structural unit, and a linking unit for rnechanically connect-ing the first structural unit to the second structural unit and for reducing a longitudinal dimension of the track processing machine along the axis of rotation.
Patent CA-3128638-A1 (CA)
Title: Breakaway assembly
Inventor: CLEVER BRYAN WILLIAM
IPC: F16L29/04
Filed: 2021-08-19
Abstract: A breakaway assembly including a first connector and a second connector releasably coupleable to the first connector. The assembly is movable between a first configuration in which the first and second connectors are releasably coupled and together define a fluid path through which fluid is flowable, and a second configuration in which the first and second connectors are not coupled together. The assembly is configured to move from the first configuration to the second configuration when a predetermined separation force is applied to the assembly. The assembly includes a closure valve positioned in one of the first or second connectors, wherein the closure valve is configured to be in an open position when the assembly is in the first configuration to allow fluid to flow therethrough, and to move to a closed position when the assembly moves to the second configuration to generally block the flow of fluid therethrough. The assembly includes an attraction member coupled to one of the first or second connectors, and a magnet unit coupled to the other one of the first or second connectors, wherein the attraction member and the magnet unit are magnetically attracted to each other when the assembly is in the first configuration to retain assembly in the first configuration. The magnet unit includes a first portion and a second portion coupled to the first portion that together define a channel therebetween, and the magnet unit further includes a plurality of magnets received in the channel.
Patent CA-3129720-A1 (CA)
Title: Method for serving parameter efficient nlp models through adaptive architectures
Inventor: TORRES TERRENCE J
IPC: G06F40/30
Filed: 2020-07-01
Abstract: A machine learning system executed by a processor may generate predictions for a variety of natural language processing (NLP) tasks. The machine learning system may include a single deployment implementing a parameter efficient transfer learning architecture. The machine learning system may use adapter layers to dynamically modify a base model to generate a plurality of fine-tuned models. Each fine-tuned model may generate predictions for a specific NLP task. By transferring knowledge from the base model to each fine-tuned model, the ML system achieves a significant reduction in the number of tunable parameters required to generate a fine- tuned NLP model and decreases the fine-tuned model artifact size. Additionally, the ML system reduces training times for fine-tuned NLP models, promotes transfer learning across NLP tasks with lower labeled data volumes, and enables easier and more computationally efficient deployments for multi-task NLP.
Patent CA-3130033-A1 (CA)
Title: Empty porous particles for use in treatment, prevention and/or postponement of degeneration of neurodegenerative diseases, neurons and glia
Inventor: FEILER ADAM
IPC: A61K38/00
Filed: 2020-04-15
Abstract: The present invention relates to empty porous particles having a diameter between 0.1 and 1000 µm, as measured by e.g. SEM, for use in diagnosis, prevention and/or postponement of neurodegenerative diseases, or for prevention and/or postponement of degeneration of neurons and glia. The invention also relates to a method of identifying biomarkers for use in diagnosis.
Patent CA-3131936-A1 (CA)
Title: Methods of anti-tumor therapy
Inventor: MINEI TAMAR R
IPC: A61K35/76
Filed: 2020-03-12
Abstract: The invention provides methods for inducing or improving an anti-tumor response in a subject having a tumor, comprising administering to the subject a priming dose of a vector which comprises a Fas-chimera gene operably linked to an endothelial cell specific promoter, wherein the priming dose of the vector is administered prior to surgical removal of the tumor or a portion thereof.
Patent CA-3131962-A1 (CA)
Inventor: ZHAO YI
IPC: H04L69/40
Filed: 2021-09-27
Abstract: Disclosed in the present invention are a data resending method, device, computer apparatus and a storage medium. The described method comprises: when the pre-set event is detected, storing the event data corresponding to the pre-set event on the data storage node, where at least one piece of the event data corresponding to the pre-set event is stored on the described data storage node; when the pre-set triggering conditions are satisfied, acquiring query parameters, obtaining the sending message based on the described query parameter and the described at least one event data stored on the data storage node; identifying the target port based on the described sending message; identifying the resending-pending data according to the described sending message and resending the described resend-pending data via the described target port. The present invention allows the auto-detection of pre-set events under multiple service scenarios and self-invoking of the port to resend data.
Patent CA-3132725-A1 (CA)
Title: Real time analysis of fluid properties for drilling control
Inventor: ELYAS ODAI
IPC: E21B44/00
Filed: 2020-03-03
Abstract: Techniques are described for controlling drilling operations based on real time measurement and analysis of fluid properties in a drilling environment. Sensor data can be collected that provides measurement(s) of fluid properties (for example, density and rheology) of the drilling fluid (in other words, downhole mud) around the drill. The measurements can be provided to a hydraulic model that calculates downhole pressure loss in the annulus. Based on this calculation, a calculation of equivalent circulating density (ECD) can be performed. In some implementations, the calculations are performed in real time with respect to the collection of the sensor data. The real time pressure loss and ECD calculations can be used to control bottom hole circulating pressures. The results of the calculations may be used to automatically control drilling operations.
Patent CA-3135734-A1 (CA)
Inventor: HEATH JULIAN
IPC: A01H5/00
Filed: 2021-10-25
Abstract: A novel canola variety designated S00630 and seed, plants and plant parts thereof. Methods for producing a canola plant that comprise crossing canola variety S00630 with another canola plant. Methods for producing a canola plant containing in its genetic material one or more traits introgressed into S00630 through backcross conversion and/or transformation, and to the canola seed, plant and plant part produced thereby. Hybrid canola seed, plant or plant part produced by crossing the canola variety S00630 or a locus conversion of S00630 with another canola variety.
Patent CA-3136663-A1 (CA)
Title: Compositions et methodes utiles pour favoriser la production de lait
Inventor: HINCK LINDSAY
IPC: C07K14/705
Filed: 2020-04-22
Abstract: L'invention concerne des procédés, des agents et des compositions pour favoriser la production de lait chez un mammifère. Les agents utiles pour favoriser la production de lait peuvent comprendre un agent qui inhibe l'activité NOTCH4. L'agent peut inhiber l'activité NOTCH4 en se liant à ROBO2 et/ou en se liant à NOTCH4. L'agent peut inhiber NOTCH4 en s'opposant à ROBO1 pour se lier à ROBO2, rendant ainsi ROBO1 disponible pour inhiber l'activité NOTCH4. L'agent peut être un domaine extracellulaire ROBO1 soluble ou un anticorps anti-NOTCH4 qui inhibe l'activité NOTCH4. L'agent peut être une construction d'ARNi qui inhibe l'expression de NOTCH4 ou une construction d'ARNi qui inhibe l'expression de ROBO2. L'invention concerne également des mammifères transgéniques génétiquement modifiés pour l'expression d'un domaine extracellulaire ROBO1 soluble ; l'inhibition de l'expression de ROBO2 ; et/ou l'inhibition de l'expression de NOTCH4. L'invention concerne également des procédés pour favoriser la production de lait chez lesdits mammifères transgéniques par l'administration d'un ou de plusieurs des agents susmentionnés.
Patent CA-3137635-A1 (CA)
Inventor: AZOM PRINCE
IPC: E21B43/241
Filed: 2021-11-04
Abstract: Disclosed are methods for producing hydrocarbons from a subterranean reservoir. The methods comprise penetrating the subterranean reservoir with a plurality of well pairs that are laterally displaced across a well pad in an array. The methods further comprise operating the plurality of well pairs under a first set of conditions that induce a solvent-concentration gradient, a temperature gradient, or a combination thereof within the subterranean reservoir by: (i) injecting varying concentrations of steam, solvent, or combinations thereof across the array, and (ii) producing hydrocarbons from the reservoir via the plurality of well pairs. The methods further comprise operating the plurality of well pairs under a second set of conditions that delocalize the solvent-concentration gradient, the temperature gradient, or the combination thereof across the array to enhance hydrocarbon production.
Patent CA-3137866-A1 (CA)
Title: Systems and methods for processing images to classify the processed images for digital pathology
Inventor: KAPUR SUPRIYA
IPC: G16H30/40
Filed: 2020-05-15
Abstract: Systems and methods are disclosed for receiving a target image corresponding to a target specimen, the target specimen comprising a tissue sample of a patient, applying a machine learning model to the target image to determine at least one characteristic of the target specimen and/or at least one characteristic of the target image, the machine learning model having been generated by processing a plurality of training images to predict at least one characteristic, the training images comprising images of human tissue and/or images that are algorithmically generated, and outputting the at least one characteristic of the target specimen and/or the at least one characteristic of the target image.
Patent CA-3138631-A1 (CA)
Inventor: KIM HONG MIN
IPC: A61L9/12
Filed: 2021-04-29
Abstract: An apparatus (10) is for cleaning flatulence of obnoxious odor, infectious virus and/or bacteria, and other contaminants. It can be mounted underneath a seat or bed provided with a flatulence collecting means ( 8). Flatulence is drawn through a series of chambers ( 15, 16, 19, 20, 22, 33, 38) with charcoal(17) provided in a first chamber(16) for removing the obnoxious odor, copper wool(32) provided in a second chamber (22) having plurality of maze-like chambers (25) for capturing and exterminating virus and/or bacteria; and a final chamber(33) having sanitizing mist (34) for eliminating contaminants.
Patent CA-3141640-A1 (CA)
Inventor: WYKES MICHELLE
IPC: C07K16/28
Filed: 2020-05-29
Abstract: L'invention concerne des molécules de liaison anti-GAL9 inhibitrices, des constructions d'anticorps, des compositions pharmaceutiques comprenant les molécules de liaison et des constructions d'anticorps, et des procédés d'utilisation de celles-ci.
Patent CA-3141899-A1 (CA)
Inventor: REININGER Dennis
IPC: F24H9/02
Filed: 2020-07-10
Abstract: L'invention concerne un procédé pour fabriquer un dispositif de chauffage (1) qui présente dans une partie intérieure (10) une soufflante (3) se trouvant derrière une grille (2). La soufflante (3) est montée dans la partie intérieure (10) et la grille (2) est montée en tant que partie du dispositif de chauffage (1). La vitesse de rotation de la soufflante (3) est déterminée sans contact par évaluation d'un comportement de réflexion de la soufflante (3), du fait qu'un signal lumineux (50) est émis à travers un évidement (20) dans la grille (2) en direction de la soufflante (3) et/ou est reçu à travers un évidement (20) dans la grille (2) à partir de la soufflante (3). L'invention concerne en outre un dispositif de chauffage (1).
Patent CA-3143503-A1 (CA)
Inventor: ROSE BRENT LORENZ
IPC: B60R11/00
Filed: 2021-12-21
Abstract: A retention member, cargo hold system, and method for securing articles while being transported in a vehicle. The cargo hold system comprises a retention member that is removably fastenable to a floor mat. The retention member comprises a first and second leg, a pin linearly translatable along a rotational axis of the retention member, and spring that biases the pin. Biasing the pin enables the first and second legs to rotate relative to each other into various configurations to form a barrier around cargo.
Patent CA-3144110-A1 (CA)
Inventor: SHAYA ILAN
IPC: H04L67/01
Filed: 2019-07-15
Abstract: A defense suite for an industrial control system (ICS) network is disclosed. The defense suite is installed and executed on a network server hosting the human-machine interface (HMI) function of the network, thereby gaining communication privileges of the HMI server to query and perform other operations with programmable logic controllers (PLCs) and other assets of the network. The defense suite further comprises a network protection engine (NWPE) that alerts a defense suite user of suspicious activity in the network. Normal behavior of the network is obtained by a learning engine, during a learning period. The learning engine can be reactivated after a configuration change in the network. The data suite also comprises an operating system protection engine (OSPE), for preventing removable devices from accessing the HMI server and a preventing execution of unauthorized executables. The OSPE is also trained for which programs are authorized through its own program discovery module.
Patent CA-3144334-A1 (CA)
Inventor: FRASCHETTI STEFANO
IPC: B32B15/14
Filed: 2020-07-02
Abstract: L'invention concerne un panneau de plancher (100) pour des moyens de transport, en particulier pour des trains, des navires ou des bateaux, le panneau de plancher (100) comprenant une plaque métallique (1) ; au moins un câble chauffant (2, 3) conçu pour générer de la chaleur lorsqu'il est traversé par un courant électrique ; un filet (4) pourvu d'une pluralité de mailles (41) ; ledit ou lesdits câbles chauffants (2, 3) étant disposés entre le filet (4) et la plaque métallique (1). Ledit ou lesdits câbles chauffants (2, 3) sont en contact avec la plaque métallique (1).
Patent CA-3145738-A1 (CA)
Title: Inhibiteurs de derive de difluorohaloallylamine sulfone de lysyl oxydases, leurs procedes de preparation et leurs utilisations
Inventor: HAMPRECHT DIETER WOLFGANG
IPC: C07C315/02
Filed: 2020-07-24
Abstract: La présente invention concerne des procédés de préparation d'une variété de dérivés de difluorohaloallylamine. La présente invention concerne également de nouveaux dérivés de difluorohaloallylamine qui sont capables d'inhiber certaines enzymes amine oxydase. Ces composés sont utiles pour le traitement d'une variété d'indications, par exemple, la fibrose, le cancer et/ou la cicatrisation chez des sujets humains ainsi que chez les animaux de compagnie et le bétail. De plus, la présente invention concerne des compositions pharmaceutiques contenant ces composés, ainsi que leurs utilisations.
Patent CA-3146534-A1 (CA)
Title: Herbicidal amides
Inventor: WITSCHEL MATTHIAS
IPC: C07D405/14
Filed: 2020-07-28
Abstract: The present invention relates to amides of formula (I), wherein the variables are defined according to the description, process for preparation, their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one amide of formula (I) to act on plants, their seed and/or their habitat.
Patent CA-3147281-A1 (CA)
Inventor: DAVIS IAN W
IPC: C12N5/00
Filed: 2020-07-06
Abstract: The invention provides recombinant DNA molecules comprising novel synthetic Intergenic Sequence Regions for use in plants to reduce the interaction of a first transgene expression cassette on a second transgene cassette when inserted between the first transgene cassette and second transgene cassette. The invention also provides transgenic plants, plant cells, plant parts, and seeds comprising the novel synthetic Intergenic Sequence Regions. The invention also provides methods to reduce the interaction between transgene expression cassettes using the novel synthetic Intergenic Sequence Regions.
Patent CA-3147917-A1 (CA)
Inventor: BOK RAYMOND L
IPC: A01D41/12
Filed: 2022-02-04
Abstract: A containment panel liner for use with a containment panel of a threshing assembly of a farm combine is provided. The containment panel liner includes an inner surface and an outer surface opposing the inner surface. A first major edge connects the inner and outer surfaces. A second major edge opposes the first major edge and connects the inner and outer surfaces. A first minor edge connects the first major edge to the second major edge and connects the inner and outer surfaces.  A  second minor edge opposes the first minor edge and connects the first major edge to the second major edge and connects the inner and outer surfaces. Taken together, the inner and outer surfaces form an arcuate cross-sectional shape that approximates an arcuate cross-sectional shape of a containment panel.
Patent CA-3150539-A1 (CA)
Inventor: JIANG FUJIE
IPC: B60L13/06
Filed: 2021-01-26
Abstract: An integrated electromagnet and a maglev train. The integrated electromagnet comprises two rows of magnetic poles located on the side surface of a magnetic yoke facing guide plate. The axes of magnetic cores are perpendicular to the side surface of the magnetic yoke. The magnetic poles comprise first and second magnetic poles, and the first and second magnetic poles in the same row of magnetic poles are arranged alternately. In a guide state the magnetic poles in the same row have the same polarity and the polarity of one row of magnetic poles is opposite to that of the other row of magnetic poles. The direction of current outputted by the bidirectional output controller in a brake state is opposite to that of current outputted in the guide state. Integrating braking function and guiding function into one integrated electromagnet can reduce the waste of brake electromagnet resources.
Patent CA-3151698-A1 (CA)
Inventor: HERNANDEZ NAVARRO SERGI
IPC: A61K8/64
Filed: 2020-07-06
Abstract: La présente invention concerne une composition cosmétique d'éclaircissement de la peau, comprenant la combinaison de sclaréolide, d'acide kojique et de glucoside d'ascorbyle, l'acide kojique étant encapsulé dans une microcapsule ou une nanocapsule ciblée ayant un récepteur cellulaire de mélanocortine 1 (MC1R) agoniste lié à la surface. Il a été découvert qu'une telle combinaison de substances actives possède un effet de blanchiment de la peau synergique. La présente invention concerne également l'utilisation cosmétique de cette composition de blanchiment de la peau, en particulier, pour l'élimination ou la réduction de marques hyperpigmentées de la peau, telles que des marques liées à l'exposition aux UV, des marques de post-cicatrice, des marques de post-inflammation, des marques de mélasme, des marques de lentigo ou des marques liées à l'âge.
Patent CA-3152563-A1 (CA)
Inventor: TUBBS KEVIN
IPC: C08L23/12
Filed: 2020-09-29
Abstract: La présente invention concerne des composés/matériaux polymères contenant des dérivés de chanvre ou de chanvre, qui présentent des comportements similaires à ceux possédés par les plastiques de pétrole classiques. La présente invention concerne en outre des procédés de production de tels composés de polymère de chanvre. La présente invention concerne enfin des compositions plastiques contenant un ou plusieurs additifs pour favoriser les propriétés antimicrobiennes du plastique.
Patent CA-3156490-A1 (CA)
Inventor: MERTENS FRANCOIS-LOUIS
IPC: H04N21/434
Filed: 2020-06-03
Abstract: Des aspects de la présente invention concernent des systèmes, des appareils et des procédés d'établissement d'un système de diffusion en ligne. Ledit système peut combiner la diffusion en continu de vidéo en direct, la vidéo à la demande (VOD), une messagerie et d'autres contenus fournis par le propriétaire de la diffusion en direct et par ses suiveurs en ligne. Le contenu multimédia peut être combiné en un flux de diffusion unique. Le propriétaire de la diffusion peut utiliser une salle de contrôle en ligne pour choisir en temps réel le flux de contenu à fournir à ses suiveurs. Une composante de jeu et/ou de partage de revenus peut également être fournie, le propriétaire et les suiveurs pouvant gagner des points lors de la visualisation et/ou de l'interaction avec des milieux parrainés dans le système.
Patent CA-3159922-A1 (CA)
Inventor: BIELFELT TERRY J
IPC: B60P7/04
Filed: 2022-05-17
Abstract: A system can include a trailer, a tarp roller, a tarp, and an arm for translating the tarp roller across the trailer. An arm can be attached to a mount disposed on a door of the trailer. The arm can include a rigid arm segment to attach to the mount and a flexible cable and a universal connecter to connect to an intermediate position on the tarp roller. An arm can include a longitudinally extending rigid arm segment having a first longitudinal axis, another longitudinally extending rigid arm segment having a second longitudinal axis, and a connector coupling the rigid arm segments together. The connector can include attach points where ends of the rigid arm segments attach to the connector. The connector can also have biasing mechanisms at the attach points to urge the rigid arm segments into an orientation. A stop can include a frame with a tab.
Patent CA-3161838-A1 (CA)
Inventor: PICKERING KEITH EDWARD
IPC: D03D13/00
Filed: 2020-12-18
Abstract: Embodiments are directed to flame resistant fabrics formed of a plurality of spun body yarns and rip stops that extend between at least some of the spun body yarns in at least one of the warp or fill direction of the fabric. In some embodiments, the rip stops include at least two relatively tough yarns, and the relatively tough yarns include an aramid spun core and a sheath.