baber/WOPTO huggingface dataset:
Patent JP-2000509055-A (JP)
Title: 殺菌剤混合物
IPC: A01N35/10
Filed: 1997-04-22
Abstract: (57)【要約】
（ａ１）下式Ｉ
 で表わされ、かつＴがＣＨまたはＮを意味し、ｎが０、１または２を意味し、Ｒがハロゲン、Ｃ 1 −Ｃ 4 アルキルまたはＣ 1 −Ｃ 4 ハロアルキルを意味するが、ｎが２である場合、２個のＲは相互に異なる基を意味してもよいカルバマートおよび／または（ａ２）下式II
 で表わされ、かつＸが水素またはアミノ（ＮＨ）を意味し、ＹがＣＨまたはＮを意味し、Ｚが酸素、硫黄、アミノ（ＮＨ）またはＣ 1 −Ｃ 4 アルキルアミノ（Ｎ−Ｃ 1 −Ｃ 4 アルキル）を意味し、Ｒ’がＣ 1 −Ｃ 6 アルキル、Ｃ 1 −Ｃ 6 ハロアルキル、Ｃ 3 −Ｃ 6 アルケニル、Ｃ 2 −Ｃ 6 ハロアルケニル、Ｃ 3 −Ｃ 6 アルキニル、Ｃ 3 −Ｃ 6 ハロアルキニル、Ｃ 3 −Ｃ 6 シクロアルキルメチル、または部分的もしくは完全にハロゲン化されていてもよく、かつ／もしくは１から３個の以下の置換基、すなわちシアノ、Ｃ 1 −Ｃ 4 アルキル、Ｃ 1 −Ｃ 4 ハロアルキル、Ｃ 1 −Ｃ 4 アルコキシ、Ｃ 1 −Ｃ 4 ハロアルコキシ、Ｃ 1 −Ｃ 4 アルキルチオを持っていてもよいベンジルを意味する場合のオキシムエーテルと、（ｂ）下式III
 で表わされ、かつＬ - がヒドロキシルまたはアセタート基を意味する場合の有機錫化合物とを相乗作用量含有することを特徴とする、殺菌剤混合物。
Patent JP-2000509230-A (JP)
Title: アンテナシステム
IPC: H01Q21/06
Filed: 1997-03-24
Abstract: (57)【要約】
本発明はアンテナシステムに関し、本発明のアンテナシステムは、容量を増大させた、組立の容易な、部品の少ない、高強度の、強風の負荷や低温に耐え得る能力を有するものである。このことは閉リング状のオープングリッド反射器構造体とダイポールエレメントとを有するアンテナシステムにより達成される。このアンテナアセンブリは、各々がダイポールエレメントを有する複数のアンテナパネルと多数のローブを支持するアンテナパネルの閉リングとを有する。好ましくは閉リングは、自己支持され放射状ビームと支柱とにより支持構造体に結合される。このアンテナシステムは輸送や製造を経済的にするため交換可能な部品からなるモジュール構成にしてある。このアンテナシステムは種々の条件に適用可能である。構成部品は航空力学の設計と苛酷な気象条件に耐える防氷手段とを有する。
Patent JP-2001505647-A (JP)
Title: 一体型レーザ／赤外線前方監視光学装置
IPC: G01J5/48
Filed: 1997-04-01
Abstract: (57)【要約】
ＦＬＩＲ／レーザーに基づく目標化および撮像システムにおいて、ＩＲのＬＯＳとレーザーのＬＯＳとの固定された整合誤差およびダイナミック整合誤差を低減することにより、当該エリア内の目標を認識し、検出し、探し、および／またはトラッキングする能力が大幅に改善される。ＩＲのＬＯＳとレーザーのＬＯＳの間の固定された整合誤差は、改善された内部ボアサイトモジュール（図１０）および対応するボアサイト方法により低減される。ダイナミック整合誤差はレーザーエネルギーおよびＩＲエネルギーの双方に対する単一ピッチ（４０５）ベアリングおよび共通ピッチ／ヨーアフォーカル（４０１）を使用する光電気サブシステムによって低減される。システムハウジング内のセグメント状ウィンドー（図７）は、光学的通路に進入する軸外れＥＭＩの量を大幅に低減する円形のＥＭＩ格子パターン（図１９）を含み、画像がデジタル化された後のＩＲ画像の画質を高めるために、改良された信号処理技術（図２６）が使用される。
Patent JP-2001514791-A (JP)
IPC: H05B6/12
Filed: 1998-03-13
Abstract: A dish-shaped core for an induction heating apparatus is provided with an excess of ferromagnetic material disposed in such a way that an increase in useful flux is obtained, in particular by reducing the reluctance near the central pole piece and near the rim part of the core.
Patent JP-2000513079-A (JP)
Title: 卓状組立基盤
IPC: F16K31/06
Filed: 1998-03-03
Abstract: (57)【要約】
本発明は、バルブユニット（３）を取外し可能に取付けるための卓状組立基盤（２）に関する。該組立基盤（２）は、モジュール式設計により、堅固な単一体として共に連結される複数の個別の基礎セグメント（２３）から成る。バルブユニット（３）は、幾つかのバルブモジュール（４）から成る。基礎セグメント（２３）として、バルブモジュール（４）と連結される幾つかの接続セグメント（２５）が配置される。それらは、バルブモジュール（４）と連通すると共に、少なくとも部分的にそれらと結合された電気及び／又は流体パワー機能装置（３８）を有する負荷ダクト（３３）を備える。
Patent JP-2001503888-A (JP)
Title: 文書インターネットｕｒｌ管理
IPC: G06F13/00
Filed: 1997-05-06
Abstract: (57)【要約】
プロパティ型ＵＲＬ（ＰＵＲＬ）を使用する方法及び装置（２００）が、３つの構成要素、即ちＵＲＬアドレスと、該ＵＲＬに対する記述的名称と、該ＵＲＬがイメージマップを表現するか否かを画定するプロパティとを有している。本発明は、例えばワードプロセサ文書、プレゼンテーショングラフィックス文書等のアプリケーション作業文書内にＰＵＲＬの埋込型リストを維持している。ＰＵＲＬは使用されることなしに文書内に格納することが可能であり、ユーザが実際のＵＲＬハイパーリンクが文書内に作成される前に、予め定めたリスト（２０２）から作業することを可能とする。ＰＵＲＬは、ＰＵＲＬリストダイアログ（２００）内にＵＲＬを手作業によってエンターさせるか、又はウエブブラウザーからＵＲＬをドラッグし且つそれを文書上にドロップすることによって画定することが可能である。ＰＵＲＬリストダイヤログ（２００）は該文書内に格納されている全てのＵＲＬのリストを示し且つ編集特徴（２０８）を供給する。
Patent JP-2000513644-A (JP)
Title: 強化耳パネルを有する使い捨て吸収体
IPC: A61F13/15
Filed: 1998-04-23
Abstract: (57)【要約】
長手方向中心線と側面方向中心線を有する吸収体が開示されており、この吸収対は、(a)後部ウエスト部と股部と前部ウエスト部と一対の長手方向縁部と体側表面とその反対側にある衣服側表面とを有する封じ込め集成体を備えており、封じ込め集成体は、トップシートと、これに接合されたバックシートと、トップシートとバックシートとの間に位置する吸収性コアと、一対のバリヤーレッグカフスとを有しており、バリヤーレッグカフスは、近位縁部と遠位縁部を有するとともに、封じ込め集成体の長手方向縁部に隣接した位置にあり、吸収対は、さらに、(b)後部ウエスト部においてバリヤーレッグカフスの近位縁部から側面方向に外側に延びている一対の後部耳パネルと、(c)前部ウエスト部においてバリヤーレッグカフスの近位縁部から側面方向に外側に延びている一対の前部耳パネルと、(d)後部耳パネルまたは前部耳パネルのうちの少なくとも一つに接合されている強化不織布とを備えており、この強化不織布は実質的に封じ込め集成体と重なり合っていない。
Patent JP-2000512314-A (JP)
Title: ピラゾリン−４，５−ジオンと芳香族第１級アミンを含有するケラチン繊維の染色用組成物
IPC: A61K8/41
Filed: 1998-03-26
Abstract: (57)【要約】
本発明は、式(Ｉ)：
 の少なくとも一つのピラゾリン-４,５-ジオンと少なくとも一つの芳香族第１級アミンを含んでなる毛髪のようなケラチン繊維の染色用組成物に関する。上記組成物は、酸化剤なしで、強く、種々で、耐性があり、先行技術のものよりも選択的ではない色調でケラチン繊維の染色をなすことを可能にする。本発明はまたかかる組成物を使用する染色方法と染色具にも関する。
Patent JP-2001525910-A (JP)
IPC: F16J15/46
Filed: 1998-04-22
Abstract: A vacuum packing configuration and installation for use therewith, has a first part and a second part. The first part includes a hydraulically or pneumatically expandable, medium-tight volume adapted to be acted upon by an hydraulic or pneumatic medium, with a wall facing the second part and forming sealing faces fastened on the first part. The wall is a resilient metal diaphragm.
Patent JP-2000512061-A (JP)
Title: 蛍光性感光材料を備えた３次元光メモリ
IPC: C03C3/16
Filed: 1998-05-20
Abstract: (57)【要約】
本発明は、蛍光性感光材料で作成されたＷＯＲＭ（write-once-read-many、書込み１回読出し多数回）型の３次元光メモリに関する。この光メモリは１光子工程および２光子工程に基づいていて、それによりディジタル情報の書込みおよび読出しを行う。読出しのために蛍光が用いられるから、高い読出し感度が得られる。本発明は、コンピュータに対して応用を有する情報の記憶および検索のための新規なデバイスの利点を有する。
Patent MX-160403-A (MX)
Inventor: HEIMAN FEDERICO P
IPC: G07F9/04
Filed: 1985-02-28
Abstract: A self-tuning coin testing apparatus having a coin sensor circuit which produces an output signal indicative of a parameter characteristic of the coins which are tested by the coin sensor and a programmed microprocessor which stores an initial acceptance limit, determines whether the output signal from the coin sensor is indicative of a valid coin, stores a signal based on the output signal for each valid coin, calculates a statistical function based on the stored signal, and finally computes and stores a new acceptance limit based on the stored signals for a predetermined number of previously accepted coins. The statistical function, is preferably weighted so that it is based upon values for only a predetermined number of the most recently accepted coins so that a recent average is maintained.
Patent NZ-190992-A (NZ)
Title: Removing water from light hydrocarbon
Inventor: BRAATHEN C W
IPC: C10G33/04
Filed: 1979-07-12
Abstract: The tendency toward ice or solid hydrate formation during cooling of a light hydrocarbon or hydrocarbon mixture such as LPG or NGL for storage or transport at sub-zero temperatures is eliminated by mixing it with aqueous methanol solution in a mixer (5), cooling the mixture in cooler (8) and thereafter separating the hydrocarbon and aqueous phase in a separator (10), the solution being chosen to be substantially insoluble in the hydrocarbon phase and freeze below the temperature to which the mixture is cooled, and at least part of the aqueous phase being recycled by pump (17) to the mixer (5) for re-use with methanol being added as required to restore its concentration in the recycling liquor towards that of the intial aqueous solution and some of the recycling liquor being removed as required to restore the quantity of circulating liquor towards its initial level. 1
Patent NZ-200406-A (NZ)
Title: Delay detonator
Inventor: YUNAN M E
IPC: F42B3/16
Filed: 1982-04-26
Abstract: improved uniformity of timing, and particularly reduced sensitivity of timing to minor variations in delay charge size, are achieved in delay detonators by placing a loose load of a flame-sensitive ignition composition between a pressed delay charge and an ignition assembly, e.g., a percussion primer, at the actuation end of the detonator. The loose ignition charge has a free surface and is adapted to be ignited in response to direct contact with flame emitted from the ignition of a charge in the ignition assembly. Preferably, the delay charge is pressed into a plastic carrier which, in a non-electric detonator, has an open end terminating between the walls of the detonator shell and a primer shell that closes the actuation end of the detonator, and the ignition charge is loosely loaded into a metal capsule seated against the delay charge.
Patent NZ-202663-A (NZ)
Title: Elasticized disposable panty,absorbent pad overlies elasticized strips at bottom edges
Inventor: KARAMI H
IPC: A41B13/04
Filed: 1982-11-30
Abstract: A disposable panty 10 and method of making the disposable panty wherein two panels 12, 14 are positioned so that four elasticized strips 24, 26, 38, 40 are bonded to the panels parallel to each other along edges 20, 22, 16, 18 of the said panels. An absorbent pad 50 is disposed between the said panels. The panels are folded together and the side edges 30, 32, 34, 36 bonded with two elasticized strips 24, 26 forming a waistband, the other strips 38, 40 in conjunction with the said absorbent pad 50 forming leg seals.
Patent NZ-219052-A (NZ)
Title: Octahydroindolizine derivatives and pharmaceutical compositions
Inventor: CARMOSIN R J
IPC: C07D471/04
Filed: 1987-01-23
Abstract: Octahydroindolizidines and corresponding ketones of the formulae (I) and (II):wherein. A is a 3-7 carbon or hetero-containing ring, R' is a substituent, n is 0-6 and x is 0-3. Also, pharmaceutical compositions for treating pain containing (II or (II) and methods for synthesis and use as well as novel intermediates in the synthesis.
Patent NZ-225418-A (NZ)
Title: Process for the preparation of aldehydes
Inventor: CORDIER J
IPC: C07C45/49
Filed: 1988-07-14
Abstract: The process for the preparation of an aldehyde of formula R-CHO in which R is an alkyl group of C1-C7 comprises according to the invention the reaction on an alkyl formate of formula H-COOR in which R has the meaning given above, of a gas constituted mainly by CO, in the presence of (a) a catalyst based on a metal chosen from among Rh, Ru, Ir, mixtures of them or a mixture of Rh and/or Ru and/or Ir with Co, Ni or Fe, (b) a promoter chosen from among iodides and mixtures of covalent compounds of iodine and a phosphine or a tertiary amine, (c) a solvent consisting of a cyclic N-alkyl amide.
Patent NZ-225916-A (NZ)
Title: Apparatus for delivering nitroglycerin to the skin
Inventor: JAEGER HALVOR
IPC: A61L15/16
Filed: 1988-08-24
Abstract: PCT No. PCT/DE88/00478 Sec. 371 Date Jun. 9, 1989 Sec. 102(e) Date Jun. 9, 1989 PCT Filed Aug. 3, 1988 PCT Pub. No. WO89/01788 PCT Pub. Date Mar. 9, 1989.The invention relates to an apparatus for the controlled delivery or release of nitroglycerin to the human or animal skin, preferably in plaster form with a nitroglycerin-impermeable backing layer, a one or multiple-part reservoir containing a pressure sensitive adhesive nitroglycerin in uniform or irregular distribution and optionally a removable protective layer impermeable for nitroglycerin, the reservoir being produced using hol melt pressure sensitive adhesives with a processing temperature of 40 DEG  to 80 DEG  C., preferably 40 DEG to 60 DEG  C. and in particularly preferred manner 40 DEG  to 45 DEG C., a process for the production thereof and the use of the apparatus for therapeutic purposes in human and veterinary medicine.
Patent NZ-236508-A (NZ)
Title: Process for alkylating (substituted) benzene in the presence of an cidic mordenite zeolite catalyst; catalyst composition
Inventor: GUO-SHUH JOHN LEE
IPC: C07C15/085
Filed: 1990-12-18
Abstract: Alkylated benzenes such as ethylbenzene and cumene are produced by alkylation and/or transalkylation in the presence of an acidic mordenite zeolite catalyst having a silica/alumina molar ratio of at least 30:1 and a crystalline structure which is determined by X-ray diffraction to have a Symmetry Index of at least 1 and an inert silica binder.
Patent NZ-239261-A (NZ)
Title: Stopping olefin polymerisation process involving chromium oxide catalyst by adding oxygen, water, ammonia or carbon monoxide as deactivating agent
Inventor: HAVAS LASZLO
IPC: C08F10/00
Filed: 1991-08-05
Abstract: The present invention relates to a process for stopping an olefin polymerisation which is carried out in a low pressure gas phase reactor, which process comprises introducing an effective quantity of deactivating agent into the reactor, characterised in that the olefin polymerisation is carried out using a chromium oxide catalyst and in that the deactivating agent is selected from oxygen, ammonia, water and carbon monoxide and is introduced over a relatively short period of time. The deactivating agent is preferably introduced into the polymerisation reactor in a quantity such that in the reactor the weight ratio of the deactivating agent to the catalyst is at least 0,001.
Patent NZ-241367-A (NZ)
Title: Pneumococcal polysaccharide-immunogenic protein conjugate
Inventor: KNISKERN PETER J
IPC: A61K39/09
Filed: 1992-01-22
Abstract: A novel conjugate vaccine comprising partially hydrolyzed, highly purified, capsular polysaccharide (Ps) from Streptococcus pneumoniae bacteria (pneumococci, Pn) linked to an immunogenic carrier protein, is produced by a new process. The conjugate is useful in the prevention of pneumococcal infections. Vaccines comprising a mixture of from one to ten different pneumococcal polysaccharideimmunogenic protein (Pn-Ps-PRO) conjugates induce broadly protective recipient immune responses against the cognate pathogens from which the polysaccharide components are derived. Young children and infants younger than 2 years old, normally unable to mount a protective immune response to the Pn-Ps alone, exhibit protective immune responses upon vaccination with these Pn-Ps-PRO conjugates.
Patent NZ-242088-A (NZ)
Title: 6-heteroaryl-4-amino benzindole derivatives, preparation and pharmaceutical compositions thereof
Inventor: BOOHER RICHARD NOLAN
IPC: A61P25/28
Filed: 1992-03-23
Abstract: 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[cd]indoles are provided which are useful in modifying the function of serotonin in mammals.
Patent NZ-244547-A (NZ)
Title: Non-sticky, smooth textured and quick-setting confection comprising 0.45-1.6% by weight gellan gum
Inventor: BELL VIRGINIA
IPC: A23L29/20
Filed: 1992-09-29
Abstract: A non-sticky, fat-containing confection which has a smooth texture and which is quick setting, comprising sugar, fat and gellan gum.
Patent NZ-248624-A (NZ)
Title: Radiophone handset: radiation directed away from user's head
Inventor: MAGGIO CLAUDIO
IPC: H01Q1/24
Filed: 1993-09-09
Abstract: The present invention relates to a portable transceiver apparatus, in particular a radiomobile telephone set, with low irradiation of the user, comprising a handset and an antenna, having an asymmetric radiation pattern, applied to said handset. Since such apparatuses, when in use, are placed alongside the user's head, a great amount of electromagnetic waves pass through it, in particular with the continuous increase in the transmission frequency and the consequent decrease in the dimension of the antenna the irradiation of the user's head is and will become a serious problem. The aim of the invention is to provide a portable transceiver apparatus so as to minimize the irradiation of its user. By using an antenna having an asymmetric irradiation pattern such as to be extremely limited in the directions of the user's head, a greatly reduced irradiation can be obtained. <IMAGE>
Patent NZ-256561-A (NZ)
Title: 4-piperazine-benzothiophene derivatives and their use in preparing pharmaceutical compositions
Inventor: BERNOTAS RONALD CHARLES
IPC: A61K31/495
Filed: 1993-09-17
Abstract: The present invention is directed to a new class of 2-optionally substituted-4-piperazine-benzothiophene derivatives of the formula     <IMAGE>  Formula I  in which Y is represented by hydrogen or C1-3 alkyl; R is represented by a substituent selected from the group consisting of hydrogen, C1-4 alkyl, C1-4 alkoxy, halogen, -CF3, -OCF3, and -OH; R1 is represented by hydrogen, cycloalkyl, C1-6 alkyl, phenyl optionally substituted, phenylalkyl, or phenylamidoalkyl; X is represented by hydrogen, -(CH2)nX1, CH=CHX1 or CHX2-(CH2)q -CH3; n is an integer from 0-2; q is either the integer 0 or 1; X1 is represented by -OH-,-OR2, -NR2R3, -CO2R2, -CONR2R3, -CN, or -COR2; R2 and R3 are each independently represented by hydrogen, C1-4 alkyl, phenyl optionally substituted, phenylalkyl, or R2 and R3 together form a (CH2)m cycloalkyl, where m=2- 6; X2 is -OR4 or -NR4R5 in which R4 and R5 are each independently hydrogen or C1-4 alkyl; and the pharmaceutically acceptable addition salts thereof; with the proviso that when n is O or X is -CH=CHX1, then X1 is not OH, OR2, or NR2R3; that are serotonin 5HT1A and 5HT1D receptor agents.
Patent NZ-262555-A (NZ)
Title: Shaped solid halogen bleach compositions comprising a continuous solid phase of an active halogen bleach source and an encapsulated active halogen bleach source
Inventor: OLSON KEITH E
IPC: C11D3/395
Filed: 1994-01-06
Abstract: Aqueous bleach solutions can be made by directing a spray of water onto a bulk or shaped solid (brick, tablet, block, etc.) comprising a continuous solid phase of an encapsulated source of an active halogen bleach or a solid comprising a source of an oxidizing active halogen bleach, and an encapsulated oxidizing halogen bleach source. Such shaped solids can be used to dispense an aqueous bleach concentrate to bleaching locus such as a washing machine.
Patent NZ-264131-A (NZ)
Title: Moulded porous thermoplastics articles having at least 10% vol open cells; preparation by extrusion
Inventor: VONKEN HUB A G
IPC: B29C48/14
Filed: 1994-07-29
Abstract: A structure 1 produced by extrusion, such as a plastics foam sheet, a board, a profiled element or the like, contains at least 10 % by volume of open cells 2, 4, which have a polyhedral shape and adjoin one another. By using an increased temperature in extrusion, in comparison with the extrusion of closed-cell thermoplastic structures, the deformation-free opening of the cells is brought about. In that case, webs 3 of cell walls 5, 6 remain unaffected in their shape, whether they have openings 7 or no passages, so that mechanial strength of the cell framework or of the three-dimensional matrix is preserved. <IMAGE>
Patent NZ-271531-A (NZ)
Title: Peptide which induces cytotoxic t lymphocyte responses to heptatitis b antigens
Inventor: CHISARI FRANCIS V
IPC: A61P31/12
Filed: 1994-08-01
Abstract: Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV polymerase, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens.
Patent NZ-303405-A (NZ)
Title: lymphotoxin-alpha and lymphotoxin-beta heteromeric complexes to treat neoplasia
Inventor: BROWNING JEFFREY L
IPC: C12N5/20
Filed: 1996-01-26
Abstract: This invention relates to compositions and methods useful for activating LT-b receptor signaling, which in turn elicits potent anti-proliferative effects on tumor cells. More particularly, this invention relates to lymphotoxin heteromeric complexes formed between lymphotoxin-a and multiple subunits of lymphotoxin-b, which induce cytotoxic effects on tumor cells in the presence of lymphotoxin-b receptor activating agents. Also within the scope of this invention are antibodies directed against the lymphotoxin-b receptor which act as lymphotoxin-b receptor activating agents alone or in combination with other lymphotoxin-b receptor activating agents either in the presence or absence of lymphotoxin-a/b complexes. A screening method for selecting such antibodies is provided. This invention also relates to compositions and methods using cross-linked anti-lymphotoxin-b receptor antibodies either alone or in the presence of other lymphotoxin-breceptor activating agents to potentiate tumor cell cytotoxicity.
Patent NZ-316312-A (NZ)
Title: Novel fused isoquinolines as dopamine receptor ligands
Inventor: NICHOS DAVID E
IPC: C07D491/056
Filed: 1996-08-16
Abstract: The present invention is directed to a novel dopamine receptor ligands of the formula:pharmaceutical formulations of such compounds, and a method using such compounds for treating a patient suffering from dopamine-related dysfunction of the central or peripheral nervous system.
Patent NZ-500916-A (NZ)
Title: Spectroscopic analysis of milk
Inventor: BERG KAREL VAN DEN
IPC: G01N33/04
Filed: 1999-11-09
Abstract: A method for analysing milk involves irradiating the milk with light at one or more different wavelengths and intensities, and detecting the light transmitted or reflected by the milk.  The light sources and associated detectors 11 may be located at various points in a milk flow path from a milking claw 1.  The sources and detectors are synchronised so that the detectors are only switched on when the light sources have reached their maximum intensity.  The measurements made by the detectors are stored, and compared with each other as well as with measurements made previously.
Patent NZ-502738-A (NZ)
Title: Triphenylethylene derivatives similar to tamoxifen or toremifene derivatives
Inventor: WIJAYARATNE ASHINI
IPC: A61K31/565
Filed: 1998-08-14
Abstract: A method of preventing conception in a female mammal by administrating a compound of the Formula I. The compound of Formula I is also useful in the treatment of estrogen-stimulated cancer, benign proliferative disorders, Alzheimer's disease, macular degeneration, urinary incontinence or Type II diabetes. Wherein; R1 is -(CH2)nCR5=CR6R7, -(CH2)mC(X)NR8R9 or Formula II; R2 and R3 are independently H, -CH3, OH, OCH3, -OCH2CH3 or -CH(CH3)2; R4 is -CN, -NO2, -CH3, -CH2CH3, -CH2CH2-Y or -Y; R5 and R6 are independently H, -C1-4alkyl, -C2-4alkenyl, -C2-4alkynyl, -X-C1-3alkyl, -X-C2-4alkenyl, -X-C2-4alkynyl or -Y; R7 is -CN, -C1-4alkyl-OH, -C(O)NR10R11, -C(O)NR12R13, -C1-4alkyl-NR10R11, -C(O)R12, -C(O)OR12, -C(O)NR12OR13, -C(O)NHC(O)R12, -C(O)NHCH2R12, -S(O)(O)(OR12), -S(O)(O)(NHCO2R12), PO3R12, -P(O)(NR12R13)(NR12R13), -P(O)(NR12R13)(OR14), -CONR12(CH2)qOCH3, -CONR12(CH2)qNR3R9oxadiazole, substituted with methyl; R8 and R9 are independently hydrogen, -C1-7alkyl, -C3-7cycloalkyl, -O-C1-7alkyl, C1-7alkyl-Y or phenyl; R10 and R11 are independently methyl or ethyl or taken together form a morpholino group bonded via its nitrogen atom; R12, R13 and R14 are independently H, -C1-12alkyl, -C2-12alkenyl, -C2-12alkynyl, -O-C1-12alkyl, -O-C2-12alkenyl, -O-C2-12alkynyl, C3-7cycloalkenyl, -C3-7cycloalkenyl linear and cyclic heteroalkyl, aryl, heteroaryl or -Y; X is oxygen or sulphur; Y is a halogen; n is an integer selected from 0, 1 or 2; m is an integer 1 or 2; p is an integer selected from 1-4; and q is an integer from 1-12.
Patent NZ-504420-A (NZ)
Title: Combination of tetrahydropyridins and acetylcholinesterase inhibiting agents, for treating senile dementia such as alzheimer dementia
Inventor: MAFFRAND JEAN-PIERRE
IPC: A61K45/00
Filed: 1998-11-09
Abstract: A pharmaceutical composition comprising: (a)  a compound selected from 1-(2-napht-2-ylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridin and a compound (I) wherein: Y is -CH- or -N-; R1 is hydrogen, halogen, hydroxyl, CF3, alkyl or alkoxyl group; R2 is hydrogen, halogen, hydroxyl, CF3, alkyl or alkoxyl group; R3 and R4 each represent hydrogen or alkyl; X is: (i) alkyl; alkoxyl; carboxyalkyl; alkoxycarbonyl alkyl; carboxyalkoxyl; or alkoxycarbonyl alkoxyl; (ii) a radical selected from cycloalkyl, cycloalkyloxy, cycloalkylmethyl, cycloalkylamino and cyclohexenyl; said radical being optionally substituted by halogen, hydroxy, alkoxy, carboxy, alkoxycarbonyl, amino, mono- or di-alkyamino; or (iii) a group selected from phenyl, phenoxy, phenylamino, N-alkyl-phenyl-amino, phenylmethyl, phenylethyl, phenylcarbonyl, phenylthio, phenylsulphonyl, phenylsulphinyl or styryl; said group capable of being mono- or polysubstituted on the phenyl group by halogen, CF3, alkyl, alkoxy, cyano, amino, mono- or di-alkylamino, acylamino, carboxy, alkoxycarbonyl, aminocarbonyl, mono- or di-alkylaminocarbonyl, amino alkyl, hydroxy alkyl, or halogeno alkyl; (b)  a compound active in the symptomatic treatment of DAT, provided that when constituent (a) is other than 1-(2naphth-2-ylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridin, the constituent (b) is an acetylcholinesterase inhibiting agent.
Patent NZ-506490-A (NZ)
Title: Improvements in tactile indicators for the visually impaired and method of installation thereof
Inventor: MCCUSKEY CELESTINE PATRICK
IPC: E01F9/04
Filed: 1999-12-23
Abstract: A tactile indicator for the visually impaired having at least one marker head (22), which in a position of use protrudes above a walkway surface.  A flange (23) extends down from the underside of the marker head (22) and is adapted for a close tolerance sliding fit into a channel cut in said walkway surface. There are a plurality of upwardly inclined ribs (25) formed on the flange (23) so that the flange (23) once push fitted into the channel is secured in place without adhesive by outward pressure of the ribs (25) on the sides of the channel.