baber/WOPTO huggingface dataset:
Patent CA-2573209-A1 (CA)
Title: Combination of dpp-iv inhibitors and compounds modulating 5-ht3 and/or 5-ht4 receptors
Inventor: VILLHAUER EDWIN BERNARD
IPC: A61K31/404
Filed: 2005-07-13
Abstract: The present invention relates to a combination, such as a combined preparation or pharmaceutical composition, respectively, comprising of a DPP IV inhibitor or a pharmaceutically acceptable salt thereof and comprising at least one therapeutic agent selected from an agent interacting with a 5-HT3 receptor and/or an agent interacting with 5~HT4 receptor, or a pharmaceutically acceptable salt thereof. The present invention furthermore relates to the use of such a combination for the prevention, delay of progression or treatment of diseases and disorders selected from selected from insulin resistance, impaired glucose metabolism, conditions of impaired glucose tolerance, conditions of impaired fasting plasma glucose, diabetes particularly type 2 diabetes mellitus, obesity, diabetic retinopathy, macular degeneration, cataracts, diabetic nephropathy, glomerulosclerosis, diabetic neuropathy, erectile dysfunction, premenstrual syndrome, coronary heart disease, hypertension, angina pectoris, myocardial infarction, stroke, vascular restenosis, skin and connective tissue disorders, foot ulceration~s and ulcerative colitis, endothelial dysfunction and impaired vascular compliance, altered gastrointestinal motility, sensitivity and/or secretion disorder(s) which include, but are not limited to, heartburn, bloating, postoperative ileus, abdominal pain and discomfort, early satiety, epigastric pain, nausea, vomiting, burbulence, regurgitation, intestinal pseudoobstruction, anal incontinence, GERD, IBS, dyspepsia, chronic constipation or diarrhea, diabetic gastropathy, gastroparesis, e.g. diabetic gastroparesis, ulcerative colitis, Crohn's disease, ulcers and the visceral pain associated therewith.
Patent CA-2575655-A1 (CA)
Title: A method of treating a gaseous mixture comprising hydrogen and carbon dioxide
Inventor: ALLAM RODNEY JOHN
IPC: C01B32/50
Filed: 2007-01-25
Abstract: Hydrogen (H2) gas and crude carbon dioxide (CO2) gas are separated from a gaseous mixture thereof. Combustible gas(es) in the crude CO2 gas are combusted to produce heat, at least a portion of which is recovered by indirect heat exchange with at least a portion of the separated H2 gas or a gas derived therefrom. The invention may be integrated with coal-fired power stations to reduce or eliminate emission of harmful components into the atmosphere.
Patent CA-2576297-A1 (CA)
Title: Triazolopyridinylsulfanyl derivatives as p38 map kinase inhibitors
Inventor: MATHIAS JOHN PAUL
IPC: C07D471/04
Filed: 2005-08-09
Abstract: A compound of formula (I), or a pharmaceutically acceptable salt and/or solvate (including hydrate) thereof; Forumla (I) and the use of a compound of formula (I) in the treatment of a TNF-mediated disease, disorder, or condition, or a p38-mediated disease, disorder, or condition, in particular the allergic and non-allergic airways diseases, more particularly obstructive or inflammatory airways diseases, preferably chronic obstructive pulmonary disease.
Patent CA-2577962-A1 (CA)
Title: Stent and method for manufacturing the stent
Inventor: JAHRMARKT SCOTT L
IPC: A61F2/06
Filed: 2005-09-01
Abstract: A stent includes a stent body (1) having a circumference, a diameter of between approximately 4 mm and approximately 12 mm, in particular, 8 mm, and a length of between approximately 10 mm and approximately 250 mm, in.  particular, 150 mm, and struts disposed helically about the circumference in turns (4). Substantially circumferentially oriented connecting bridges (8) connect respectively adjacent ones of the turns. A method for manufacturing a helical stent includes the steps of providing a stent body with struts disposed about the circumference thereof in turns and with bridges connecting the struts in adjacent turns. The stent body is expanded and, thereafter, some of the bridges, in particular, sacrificial bridges, are removed.
Patent CA-2580844-A1 (CA)
Title: Heterocyclic derivatives and their use as mediators of stearoyl-coa desaturase
Inventor: KAMBOJ RAJENDER K
IPC: A61K31/501
Filed: 2005-09-20
Abstract: Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): Formula (I) where x, y, G, J, L, M, V, W, R2, R3, R4, R5, R5a, R6, R6a, R7, R7a, R8 and R8a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Patent CA-2582702-A1 (CA)
Inventor: MULLEN JOSHUA O
IPC: B62B1/24
Filed: 2007-03-20
Abstract: A wheelbarrow that includes a frame assembly and a hopper assembly. The frame assembly has at least one wheel rotatably coupled thereto and a forward extension extending beyond the at least one wheel. The hopper assembly has a hopper. The hopper is pivotally coupled to the frame assembly at a first pivot point.  The forward extension has a ground contact point structured to act as a second pivot point. The hopper is structured to be emptied by pivoting the hopper about either the first or the second pivot points. The first and second pivot points are stationary pivot points when the hopper is being emptied.
Patent CA-2586715-A1 (CA)
Inventor: VAN VLIJMEN MICHAEL BERNARDUS
IPC: C11D3/22
Filed: 2005-11-28
Abstract: Toilet bar compositions are described that contain specific odor masking agent(s). The odor masking agent(s) reduce malodor without the need for elevated amounts of masking fragrances that individuals may not prefer, and who use the composition for personal cleansing or who are exposed to the composition.
Patent CA-2587008-A1 (CA)
Title: Forming fabrics
Inventor: EAGLES DANA
IPC: D21F1/00
Filed: 2005-11-02
Abstract: A papermaker~s fabric for use as a forming fabric. The fabric may include bondable or meltable monofilament yarns which may be formed from materials that retain substantial strength and tenacity after thermal treatment.  Further, the remaining yarns in the forming fabric may be formed from materials that have a higher melting temperature than the monofilament material that will be thermally bonded or melted.
Patent CA-2587046-A1 (CA)
Inventor: BUNICK FRANK J
IPC: A61J3/00
Filed: 2005-10-26
Abstract: The present invention provides an edible dosage form that incorporates optical elements (e.g., printed patterns, microrelief gratings, and/or macrorelief gratings), capable of producing unique optical effects and images in order to enable a user to better identify and differentiate the dosage forms, as well as to improve the detection of counterfeit production thereof, wherein the edible dosage forms may be made in a variety of ways to incorporate the optical elements therein.
Patent CA-2587162-A1 (CA)
Title: Method of producing macrocyclic ketone, and intermediate thereof
Inventor: MATSUDA HIROYUKI
IPC: C07C69/96
Filed: 2004-11-11
Abstract: A process for producing muscone by methyl addition to the 1,4-conjugation of 2-cyclopentadecenone. By the process, muscone is produced in high yield not under reaction conditions including an extremely low temperature and a low concentration but under practical conditions. The process comprises subjecting 2-cyclopentadecenone to a 1,4-conjugation addition reaction with an organometallic methylation reagent in the presence of a copper catalyst or nickel catalyst and an enol anion-trapping agent to obtain a 3-methyl-1-cyclopentadecene derivative represented by the general formula (II): (II) and then solvolyzing the enol moiety of this 3-methyl-1-cyclopentadecene derivative to obtain muscone.
Patent CA-2587224-A1 (CA)
Title: Microcin b17 analogs and methods for their preparation and use
Inventor: PICKETT CHRISTOPHER JOHN
IPC: C07K7/06
Filed: 2005-11-18
Abstract: The present invention pertains to synthetic analogues of microcin B17 component units, methods of making and using these analogues, including, for example, as inhibitors of DNA gyrase. More particularly, the present invention pertains to compounds of the Formula (1) wherein: W is independently: -H or a peptide group; Z is independently: -OH or a peptide group; wherein each peptide group, if present, is: an amino acid group and comprises exactly one amino acid, or: a poly(amino acid) group and comprises two or more amino acids; RN3 is independently: -H, C1-6alkyl, C2-6alkenyl, C3-6cycloalkyl, or C3-6cycloalkenyl, C6-14carboaryl, C5-14heteroaryl, C6-14carboaryl-C1-6alkyl, C5-14heteroaryl-C1-6alkyl, and is optionally substituted; the circle represents a mono-heterocycle or a bis-heterocycle, wherein the heterocycle, or each of the two heterocycles, is a five membered ring having at least a first ring heteroatom that is N, and optionally a second ring heteroatom that is selected from N, O, and S; and the heterocycle, or each of the two heterocycles, is optionally substituted with one or more substituents; and pharmaceutically acceptable salts, amides, esters, solvates, and hydrates thereof. The present invention also pertains to uses of such compounds, for example, to inhibit DNA  Gyrase activity in a cell and in methods of therapy, for example, to treat a disease or condition that is ameliorated by the inhibition of DNA Gyrase, such as a bacterial infection, cancer, etc.; as a herbicide; as a microbicide; as a bactericide; etc.
Patent CA-2587324-A1 (CA)
Inventor: VASSALLO GODFREY
IPC: G08B29/00
Filed: 2005-02-01
Abstract: L'invention concerne un nouveau système et un nouveau procédé destinés à simplifier la gestion d'un matériel électronique tel qu'ordinateurs, réseaux et systèmes de matériel et de communication. Le système effectue un suivi d'un matériel qui a été enregistré dans une base de données d'inventaire sans participation de l'utilisateur. Une fois enregistré et connecté dans le dispositif constituant la source d'énergie du système, l'emplacement du matériel peut être facilement suivi sans intervention humaine. Cette information peut être utilisée pour localiser des systèmes devant être rénovés, réparés ou installés en d'autres emplacements. Elle permet en outre de vérifier qu'un matériel correct a été déplacé et qu'il a été amené en l'emplacement correct.
Patent CA-2588615-A1 (CA)
Title: Valve unit for filling machines
Inventor: CONFORTI LUCIO
IPC: B67C3/28
Filed: 2007-05-11
Abstract: The present invention relates to a valve unit for container filling machines, particularly for glass bottle fillers.     More particularly, the present invention relates to a valve unit (1), particularly for container filling machines (8), comprising a hollow body (2) in which there is slidably housed a plug (3), wherein said plug (3) is hollow and comprises an outer duct (23) and an inner duct (24) coaxial to said outer duct (23), a probe (28) having a smaller diameter than the opening of said inner duct (24) being coaxially housed within said inner duct (24), characterized in that said inner duct (24) is made of electrically isolating material.
Patent CA-2588892-A1 (CA)
Title: Anti-il-1r1 single domain antibodies and therapeutic uses
Inventor: DREW PHILIP D
IPC: A61K47/48
Filed: 2005-12-01
Abstract: Disclosed is the use of an antagonist of Interleukin 1 receptor type 1 (IL-1R1) for the manufacture of a medicament treating, preventing or suppressing lung inflammation or a respiratory disease. In some embodiments of the described invention, the medicament is for local administration to pulmonary tissue. Also disclosed are methods for treating lung inflammation or a respiratory disease.
Patent CA-2590128-A1 (CA)
Title: Method and apparatus for purifying an oil-based fluid
Inventor: BROWNE NEALE
IPC: B03C5/00
Filed: 2005-12-16
Abstract: PA-02031WO An apparatus for electrophoretically removing contaminants from an oil-based drilling fluid includes a housing, a drum, a means for rotating the drum, and a scraper head. The drum is retained within the housing above the housing floor. The oil-based drilling fluid is directed along the housing floor, contacting both the housing floor and the drum. A negative charge is applied to the drum and a positive charge is applied to the housing, creating an electrical field through the fluid. Drilling fluid contaminants are attracted to and collect upon the drum outer surface. The means for rotating the drum turns the drum through the fluid and collected contaminants remain on the drum outer surface. The scraper removes the collected contaminants from the drum outer surface as it rotates. A method for removing contaminants from an oil-based drilling fluid includes directing the contaminated into the electrically charged housing, adjusting the drum height of the oppositely electrically charged drum so that it contacts the fluid, rotating the drum to remove the contaminants collected thereon from the fluid, and scraping the drum with a nonconductive scraper head to remove the contaminants.
Patent CA-2592519-A1 (CA)
Title: Methods and apparatus for tracking consumer preferences in a video rental system
Inventor: ELLIS AUBREY JUDSON JR
IPC: H04N5/93
Filed: 2005-11-16
Abstract: Apparatus and methods for gathering information about a customer's preferences, storing the customer's preferences in a memory, selecting informational content to be added to the rented video medium based upon the customer's preferences, adding the selected informational content to the rented video medium, extracting customer information from the video medium upon its return; storing of the extracted customer information in a memory and preparing reports that include the number of times that the informational content was viewed by customers. The customer may also respond interactively to the added informational content.
Patent CA-2594430-A1 (CA)
Inventor: GOSSETT JAMES LEROY
IPC: F16K47/08
Filed: 2005-12-08
Abstract: A control valve includes a first component, a second component, and a seal disposed there between. The first component defines a first surface that comprises a steel material, and the second component defines a second surface that comprises a steel material. The seal is disposed between the first and the second surfaces and comprises a boronized graphite material.
Patent CA-2596603-A1 (CA)
Title: Volumetric rotary machine with rotors having asymmetric profiles
Inventor: GOEPFERT OLIVIER
IPC: F04C18/16
Filed: 2005-02-16
Abstract: Rotary displacement machine having a housing and at least two twinned rotors of asymmetrical profile, the twinned rotors each made of a core on which projects a helicoidal thread which extends above the core like a tooth. The helicoidal thread having a first predetermined dimension in a direction radial to the longitudinal axis of the twinned rotors and above the surface of a rotor. The machine having a first flank with a position and length of arc predetermined such that the shape of the first flank and the shape of the second flank each connect to one of the opposite ends of a connecting segment which constitutes a helicoidal surface. The connecting segment having a second predetermined dimension in a direction radial to the longitudinal axis of the twinned rotors such that the ratio of the second dimension over the first dimension ranges between 0.005 and 0.1.
Patent CA-2598324-A1 (CA)
Inventor: TILTON ANDREW THOMAS
IPC: B65D41/04
Filed: 2007-08-22
Abstract: An audible closing feature for threaded containers with a threaded lid, the container and lid including a lug and notch arrangement that provides an audible indication that the lid is sufficiently closing the container as well as providing for minimal resistance when removing the lid from the container. The audible closing feature further reduces or eliminates backoff between the lid and container during transport and/or storage. The lid and container contain at least one of either the lugs and notches, such that a lug is received by a notch to provide the audible indication that the lid is sufficiently closing the container.
Patent CA-2601582-A1 (CA)
Title: Vehicle suspension system for stable squat magnitude responses
Inventor: WEAGLE DAVID
IPC: B60K17/00
Filed: 2006-04-07
Abstract: A wheel suspension system having under powered acceleration a stable squat magnitude response.
Patent CA-2602459-A1 (CA)
Title: Removable device comprising collapsible floats, which is used to convert a monohull vessel into a multihull vessel, and vessel comprising same
Inventor: JOUFFROY FREDERIC
IPC: B63B1/12
Filed: 2006-03-23
Abstract: A device (1) for converting a monohull vessel (2) into a multihull vessel, includes a support structure (3) which is removably fixed to the vessel (2) and at least one lateral float (4) which is solidly articulated with the support structure (3) around at least one geometrical axis (BB′). The aforementioned float (4) can occupy (i) a first stable deployed position in which it is parallel to the vertical longitudinal geometric plane (PP′) containing the keel line of the vessel (2) and, at the lowest point of the keel line thereof, it is disposed beneath the geometric axis (BB′) and (ii) a second stable collapsed position which is separated at an angle from the first position. A vessel equipped with the device is also disclosed.
Patent CA-2602563-A1 (CA)
Title: Combinations comprising at least one direct thrombin inhibitor for the treatment of thrombosis
Inventor: REILLY PAUL A
IPC: A61K31/4709
Filed: 2006-03-27
Abstract: The present invention relates to novel pharmaceutical compositions comprising at least one direct thrombin inhibitor and at least one additional active compound selected from the groups consisting of platelet inhibitors, low molecular weight heparins (LMWH) and heparinoids as well as unfractionated heparin, factor Xa inhibitors, combined thrombin/factor Xa inhibitors, fibrinogen receptor antagonists (glycoprotein IIb/IIa antagonists) and Vitamin K antagonists, optionally together with one or more pharmaceutically acceptable excipients or carriers for the treatment of thrombosis.
Patent CA-2603288-A1 (CA)
Title: Produits bitumineux, leur melange avec des granulats et leurs utilisations
Inventor: FRABOULET LOIEC
IPC: C09K23/00
Filed: 2006-04-04
Abstract: La présente invention concerne des produits bitumineux anhydres contenant un ou plusieurs additifs spécifiques qui permettent de baisser de manière surprenante la température de production des mélanges de granulats et de produit bitumineux d'une amplitude de 20 à 40 0C, la température du mélange entre granulat et produit bitumineux lors du répandage d'une amplitude de 10 à  40 0C et la température du mélange entre granulat et produit bitumineux à  cAEur au cours du compactage, quand il a lieu, d'une amplitude pouvant aller jusqu'à 50 0C, sans dégrader les propriétés normalisées du produit bitumineux et du mélange entre produit bitumineux et granulats, tout en conservant une conduite du procédé, depuis le transport jusqu'au compactage éventuel conforme à l'état de l'art. Ces mélanges de granulats et de produit bitumineux sont particulièrement adaptés pour l'étanchéité, la construction et l'entretien de tapis routiers, de trottoirs et 5 pistes d'aviation.
Patent CA-2603879-A1 (CA)
Title: Additive for hydrocarbon fuel consisting of non-acidic inorganic compounds of boron and related processes
Inventor: BAXTER EDWARD C JR
IPC: C10L1/12
Filed: 2006-04-21
Abstract: The present invention provides a fuel additive and a process for using and making the fuel additive. The fuel additive includes a non-acidic boron-containing salt in a carrier fluid. The fuel additive enhances combustion by increasing fuel efficiency or decreased pollutant output in an exhaust gas resulting from combustion of the fuel with the fuel additive.
Patent CA-2604277-A1 (CA)
Inventor: SATTMANN RALPH
IPC: G01N27/62
Filed: 2007-09-26
Abstract: The invention relates to an immersion sensor for analysis of liquids or melts, comprising an immersion carrier, which includes a detector and a radiation-guiding unit, and also comprising a sample chamber with an inlet opening arranged in the immersion carrier, wherein the sensor for measurement of the melt is formed inside the sample chamber.
Patent CA-2604437-A1 (CA)
Inventor: SELINFREUND RICHARD H
IPC: G11B7/24
Filed: 2006-04-14
Abstract: An optical medium piracy system employing a state-change material in association with a digital data indicia, wherein when state-change material is activated to change state, the optical medium moves from an unreadable to a readable condition, or from a less readable to more readable condition.
Patent CA-2604592-A1 (CA)
Inventor: WATKINS BRIAN A
IPC: A63F9/24
Filed: 2006-03-28
Abstract: A random number is generated (204) using two or more designations taken from a ball draw and applied to affect a game. The random number generation process preferably results in a uniform distribution of random numbers across a certain range. The uniformity in which the random numbers may be distributed over a certain range allows the numbers to be employed to affect games in a uniform and unbiased fashion (206).
Patent CA-2605404-A1 (CA)
Inventor: RICHTER JACOB
IPC: A61F2/07
Filed: 2006-03-03
Abstract: The present invention relates to covered endoprosthetic devices. Covered endoprosthetic devices comprise an endoprosthesis and a sheath. The sheath comprises a central portion and outer portions, wherein the central portion preferentially restricts or causes a restriction of blood flow. Blood flow can be reduced by the central portion of the sheath by varying the permeability of the sheath or by having projections on the sheath that slow blood flow.  Permeability may be provided by perforations or holes in the material of the sheath or by varying the polymer structure that makes up the sheath itself.  The outer portions of the sheath do not substantially reduce blood flow.  Methods of using sheath-covered endoprosthetic devices of the invention to treat aneurysms, especially aneurysms in proximity to small perforator vessels or arteries, are also encompassed.
Patent CA-2605691-A1 (CA)
Title: Spinous process stabilization devices and methods
Inventor: BRUNEAU AURELIEN
IPC: A61B17/70
Filed: 2006-05-01
Abstract: Devices and methods for supporting adjacent spinous processes include opposing plates movable toward one another along a cross post to contact opposite sides of each of the spinous processes, and a spacer member about the cross post contacting the adjacent surfaces of the spinous processes to resist movement of the spinous processes toward one another under spinal extension motion.
Patent CA-2608394-A1 (CA)
Title: Methods of preparing 3-cyano-quinolines and intermediates made thereby
Inventor: CHEW WARREN
IPC: C07D213/30
Filed: 2006-04-27
Abstract: The present invention relates to methods for preparing substituted 3-cyanoquinolines and intermediates obtained by the methods of the present invention. The methods of the invention comprise reacting an N-aryl-2-propanimide with phosphoryl chloride to produce the substituted 3-cyanoquinolines. The methods further comprise reacting arylamines, orthoformates and active methylenes to produce the N-aryl-2-propenamide.
Patent CA-2611185-A1 (CA)
Inventor: GERICKE BERND
IPC: F01K3/20
Filed: 2006-06-03
Abstract: The invention relates to a steam generation plant, comprising a steam generator (1) with a combustion chamber (8), an evaporator, a superheater (9), an intermediate superheater (12), a condenser (14), a feed water preheater (16, 19, 19') regeneratively heated by steam, a steam turbine set (2) with a high-pressure section (4), a medium pressure section (5) and a low-pressure section (6), a flue gas line (22), connected to the combustion chamber (8), an air supply line (21), for the supply of combustion air to the burner in the combustion chamber (8) and an air preheater (3) with flue gas and combustion air passing therethrough. An air line (23) branches off from the air supply line (21) downstream of the air preheater (3) in said steam generation plant and supplies an air-fractionation unit (25). Air coolers (34, 35) are arranged in the air line (23) through which the condensate or feed water from the condensate/feed water circuit from the steam generator (1) flows. The oxygen output from the air fractionation unit (25) is connected to the burner of the combustion chamber (8) by means of an oxygen line (26).