baber/WOPTO huggingface dataset:
Patent CA-2317424-A1 (CA)
Title: Combination of a gaba-a alpha 2/3 agonist and a selective serotonin reuptake inhibitor
Inventor: DAWSON GERARD RAPHAEL
IPC: A61K31/135
Filed: 1999-01-19
Abstract: The present invention provides a pharmaceutical product comprising an SSRI and a non-sedating anxiolytic compound which is a modulator of the benzodiazepine binding site of the human GABAA receptor, having a binding affinity (Ki) for the .alpha.3 subunit of the human GABAA receptor of 10 nM or less, which elicits at least a 40 % potentiation of the GABA EC20 response in stably transfected recombinant cell lines expressing the .alpha.3 subunit of the human GABAA receptor, and which elicits at most a 30 % potentiation of the GABA EC20 response in stably transfected cell lines expressing the .alpha.1 submit of the human GABAA receptor for simultaneous, separate or sequential administration.
Patent CA-2318984-A1 (CA)
Inventor: LEIGHTON STEPHEN B
IPC: G01N1/08
Filed: 1999-02-24
Abstract: An array-based technology facilitates rapid correlated gene copy number and expression profiling of a very large numbers of human tumors. Hundreds of cylindrical tissue biopsies (diameter 0.6 mm) from morphologically representative regions of individual tumors can be arrayed in a single paraffin block. Consecutive sections from such arrays provide targets for parrallel in situ visualization and quantitation of DNA, RNA or protein targets. For example, amplifications of six loci (mybL2, erbB2, Cyclin-D1, myc, 17q23 and 20q13) were rapidly determined by fluorescence in situ hybridization from 372 ethanol-fixed breast cancers. Stratification of tumors by estrogen receptor and p53 expression data revealed dictinct patterns of gene amplification in the various subgroups of breast cancer that may have prognostic utility. The tissue array technology is useful in the rapid molecular profiling of hundreds of normal and pathological tissue specimens or cultured cells.
Patent CA-2322090-A1 (CA)
Inventor: RATHUNDE DALE FRANK
IPC: H04W4/12
Filed: 2000-10-03
Abstract: A wireless communication network includes at least two programmable application processors (APs) for message processing. Each AP runs one or more active radio control software (RCS) instances on behalf of a defined cell group and one or more standby RCS instances on behalf of at least one other cell group. Each cell in the network is connected to a pair of APs. One AP runs an active RCS instance on behalf of the cell and the other AP runs a standby RCS instance on behalf of the cell.  What is disclosed is a system and method for performing dynamic load balancing during system operation between a pair of APs (AP pair) serving at least one cell in common.  In a first step, selection is made, relative to at least one cell served by the AP pair, of a first RCS instance running as an active RCS instance on one member of the AP pair and a second RCS instance running as a standby RCS instance on the other member of the AP  pair. The first RCS instance is redesignated as a standby RCS instance for the cell and the second RCS instance is redesignated as an active RCS instance for the cell.  Active message processing is then transferred from the first RCS instance to the second RCS instance during network operation and without service interruption to the cell. In a variation the foregoing, an entire group of RCS instances (active or standby) can be moved from one AP to another. Also disclosed is a distributed mated-pair processor arrangement in which the standby RCS instances for a cell group are distributed across multiple APs.
Patent CA-2322871-A1 (CA)
Title: Process gas purification and fuel cell system
Inventor: WOODS RICHARD R
IPC: H01M8/06
Filed: 1999-03-10
Abstract: A module (214 Fig. 5) for separating a product from a mixed stream comprises a mixed stream chamber having inlet and outlet means and defining a first flow path for the mixed stream, a purge/product stream chamber having inlet and outlet means and defining a second flow path for a purge/product stream, the second flow path having a substantially countercurrent direction to that of the first flow path, and a membrane located between the mixed stream chamber and the purge/product stream chamber, the membrane being selectively permeable to the product. There is also disclosed a fuel cell system comprising a burner module (210) for mixing and combusting a fuel and air mixture to produce hydrogen rich fuel stream; a hydrogen fuel cell (250) for producing power/energy using the hydrogen fuel produced by the burner module; a hydrogen purification module (214) between the burner module and the fuel cell for extracting hydrogen fuel from the burner module for use in the fuel cell and that uses a purge gas to enhance purification module performance; hydrogen storage means (254) for storing hydrogen fuel produced by the burner module and not immediately required by the fuel cell; and means for feeding stored hydrogen fuel from the storage means to the fuel cell when the hydrogen requirements of the fuel cell are greater than the amount of hydrogen produced in the burner module.
Patent CA-2324725-A1 (CA)
Inventor: MAYR MARTIN
IPC: H02K9/19
Filed: 2000-10-27
Abstract: The electric motor has a housing, in which a stator and a rotor are disposed. The whole of the interior of the housing, with the exception of a stator borehole, which forms an accommodating region for the rotor, is filled with a thermally conductive composition of high impact strength. This composition surrounds the windings of the stator and protects the windings against damage that can be caused by ground material with sharp edges, which flows through the electric motor together with aspirated cooling air. A good dissipation of heat from the central region of the electric motor to the housing of the electric motor results because the composition has a very good thermal conductivity.
Patent CA-2326143-A1 (CA)
Inventor: GOULET MARK T
IPC: A61K31/439
Filed: 1999-03-29
Abstract: There are disclosed compounds of formula (I), and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related and other conditions in both men and women.
Patent CA-2327374-A1 (CA)
Inventor: CAMBON JEAN-LOUIS
IPC: B64C7/02
Filed: 2000-12-06
Abstract: Selon l'invention, le mât de suspension (3) comporte un carénage de réduction de perte locale de sustentation et sa section de largeur maxi- male (7) est disposée à l'avant de la partie arrière (4R), concave et en retrait, de l'intrados (4) de la voilure (1). Le carénage de réduction de perte locale de sustentation (8): est logé, au moins pour la plus grande part de sa hauteur, dans la concavité de ladite partie arrière (4R) de l'intrados (4) de la voilure (1), et comporte une face inférieure (15) qui se rapproche de sa surface su- périeure (13) en prolongement aérodynamique de l'extrados (14) de la voilure (1) pour donner, à la partie arrière saillante (12) dudit caré- nage (8), la forme d'une lame s'amincissant vers l'arrière et terminée par un bord de fuite aérodynamique (16).
Patent CA-2329040-A1 (CA)
Title: Method for producing hexanediol
Inventor: BREITSCHEIDEL BORIS
IPC: C07C29/149
Filed: 1999-04-12
Abstract: The invention relates to a method for producing hexanediol by hydrogenating adipic acid dialkyl esters or mixtures containing adipic acid dialkyl esters as an essential constituent and organic halogen compounds as impurities. According to said method, the adipic acid dialkyl esters or the mixtures containing adipic acid dialkyl esters are guided over copper catalysts at a temperature of 50 to 250 ~C and at a pressure of 1 to 100 bar before hydrogenation in order to remove the organic halogen compounds. Said copper catalysts contain 0.5 to 80 wt. % copper calculated as CuO and have a surface of 5 to 1500 m2/g, 0.05 to 1.5 cm3/g porosity and a copper surface of 0.1 to 20 m2/g.
Patent CA-2331759-A1 (CA)
Inventor: MORITA KAZUHIRO
IPC: C07C1/04
Filed: 2001-01-22
Abstract: A method for manufacturing a synthesis gas, which makes it possible to procure CO2 inside a synthesis gas-manufacturing plant utilizing the Fisher-Tropsch reaction system, thereby enabling the synthesis gas to be cheaply manufactured by way of the Fisher-Tropsch reaction system without being restricted by the location of CO2 gas source such as an ammonia plant, the synthesis gas comprising a molar ratio of H2/CO suited for synthesizing gasoline, kerosene and gas oil.      This method comprises the steps of, feeding a steam-mixed natural gas to a reformer provided with a combustion radiation portion for burning a fuel, the reformer being heated by the combustion radiation portion, recovering carbon dioxide from a combustion exhaust gas generated at the combustion radiation portion, and adding the carbon dioxide to the steam-mixed natural gas at a location on an upstream side of the reformer, thereby allowing a reforming reaction to take place to obtain a synthesis gas comprising CO and H2 at a molar ratio of H2/CO = 1 to 2.5.
Patent CA-2333102-A1 (CA)
Inventor: VARGO RICHARD DAVID
IPC: B29C31/00
Filed: 1998-06-01
Abstract: Cette invention concerne un revêtement hybride (40) ainsi qu'un système servant à l'utilisation de ce revêtement hybride. Ce revêtement comprend une première partie (42) qui est faite d'un premier matériau, ainsi qu'une seconde partie (44) qui est faite d'un matériau distinct. Les deux matériaux possèdent des propensions différentes à l'adhérence sur un composant caoutchouteux non vulcanisé (20), ainsi que des coûts différents. Cette invention consiste à utiliser le revêtement le moins collant et le plus cher dans les zones du rouleau de revêtement où un collage a le plus de chance de se produire, et à utiliser le matériau moins cher là où l'adhérence du revêtement au caoutchouc pose moins de problèmes.
Patent CA-2335247-A1 (CA)
Title: Method for manufacturing a laminate consisting of individual layers
Inventor: VON FALKENHAUSEN CHRISTIAN
IPC: A61K9/70
Filed: 1999-06-07
Abstract: The invention relates to a method for manufacturing a laminate consisting of individual layers and comprising the following steps: initially preparing a substrate serving as a support and applying a flowable material as a layer under processing conditions. The invention is characterized in that at least one flowable material is subsequently applied under processing conditions as additional layer and in that at least one layer contains at least one pharmaceutical or cosmetic active substance and/or adjuvant.
Patent CA-2335711-A1 (CA)
Title: 4,5,6 and 7-indole and indoline derivatives, their preparation and use
Inventor: MIKKELSEN IVAN
IPC: C07D209/14
Filed: 1999-06-14
Abstract: A substituted 4-, 5-, 6-, and 7-indole or indoline derivative of Formula (I)  wherein A is a group having formula (IIA), (IIB), (IIC) wherein X, U, Y, R3 to R12, Z, W, n and m are as defined above. The compounds are potent serotonin reuptake inhibitors and have 5-HT1A receptor antagonistic activity.
Patent CA-2336049-A1 (CA)
Inventor: ANDERSON IAN MCARTHUR
IPC: B65B55/02
Filed: 1999-06-25
Abstract: A sterilisation and filling apparatus, method and plug arrangement for aseptic filling of sterile containers. The apparatus includes a filling nozzle comprising a tubular body (16) with a flow passage (19) therethrough and a plug (22) closing the flow passage; a sterilisation and filling head (39) movable towards and away from the tubular body with outer (40) and inner (42) annular sealing rings engaging annular sealing faces on the tubular body and plug respectively and a sterilisation chamber (44) located inwards of the outer sealing ring, and a cavity in the filling head to receive the plug.  Sterilisation fluid supply means supplies fluid to the chamber (44). Plug extractor jaws (70) extract the plug (22) from the tubular body (16) and store the plug in the cavity in the head and filling means fill the container through the head. The plug (22) includes gripping formations for the jaws (70). The plug (22) and tubular body (16) may include ribs and recesses as retaining means and sealing welds or elastomeric rings cooperative before and/or after filling.
Patent CA-2337871-A1 (CA)
Title: Optical mammography
Inventor: PORATH ASHER
IPC: A61B5/00
Filed: 1998-07-30
Abstract: Apparatus for imaging cross-sectional views of the inner structure of the breast, the apparatus comprising: a source of light (12) illuminating the breast situated at a first position of the breast; a matching interface (19)  situated, at a second position, on a surface of the breast, which reduces scatter caused by said surface; and an imaging detector (24) focused on a plane within the breast, through said matching interface.
Patent CA-2341211-A1 (CA)
Title: Intelligent network interface device and system for accelerating communication
Inventor: BOUCHER LAURENCE B
IPC: H04L12/56
Filed: 1998-11-20
Abstract: An intelligent network interface card or communication processing device (30 ) works with a host computer (20) for data communication. The device provides a fast-path (159) that avoids protocol processing for most messages, greatly accelerating data transfer and offloading time-intensive processing tasks fr om the host CPU (28). The host retains a fallback processing capability for messages that do not fit fast-path criteria, with the device providing assistance such as validation even for slow-path messages, and messages bein g selected for either fast-path or slow-path (158) processing. A context (50) for a connection is defined that allows the device to move data, free of headers, directly to or from a destination or source in the host. The contex t can be passed back to the host for message processing by the host. The devic e contains specialized hardware circuits that are much faster at their specifi c tasks than a general purpose CPU. A preferred embodiment includes a trio of pipelined processors (482, 484, 486) devoted to receive, transmit and utilit y processing, providing full duplex communication for four Fast Ethernet nodes .
Patent CA-2341618-A1 (CA)
Title: Proanthocyanidin-containing composition
Inventor: KOBAYASHI ASAKO
IPC: A23L1/30
Filed: 2001-03-20
Abstract: A composition and method for stabilizing proanthocyanidin, especially for preventing, for example, its discoloration by oxidative polymerization. The method utilizes (and the composition contains) proanthocyanidin, and an amino acid having a hydroxyl group or a dipeptide containing said amino acid. Also shown is a drink, food, cosmetic or medicament which contains the composition.
Patent CA-2341758-A1 (CA)
Title: Multilayer dielectric evanescent mode waveguide filter
Inventor: DE LILLO ROCCO A
IPC: H01P1/219
Filed: 1999-08-27
Abstract: A multilayer dielectric evanescent mode waveguide bandpass filter (100) with resonators (10a, 11a) utilizing via hole technology capable of achieving very narrow bandwidths with minimal insertion loss and high selectivity at microwave frequencies is provided. The resonators (10a, 11a) may also be used as feed posts (1, 2). A typical implementation of this filter (100) is fabricated with soft substrate multilayer dielectrics with high dielectric constant ceramics. This filter (100) typically takes up less space than other filters presently available. A typical implementation operates at a center frequency of 1 GHz, although other center frequencies, such as approximately 0.5 GHz to approximately 60 GHz, are achievable. The perimeter of the filter (100) may be defined by via holes or plated slots.
Patent CA-2342435-A1 (CA)
Title: A pharmaceutical composition for inhibiting non-intentional behavior and use of a running neuron inhibitory substance for producing the pharmaceutical composition
Inventor: BANNAI MAKOTO
IPC: A61K31/4409
Filed: 2001-03-28
Abstract: It is an object of the present invention to provide a pharmaceutical composition, which permits the inhibition of nori-intentional motions such as poriomania and hyperkinesia without any inhibition of intentional motions and in particular to provide a pharmaceutical composition capable of treating patients suffering from, for instance, poriomania and hyperkinesia. Moreover, it is also an object of the present invention to provide a method of using running neuron-inhibitory substances. A pharmaceutical composition for treating a patient suffering from symptoms accompanied by non-intentional motions such as poriomania and hyperkinesia, comprising a substance capable of pre-synaptically or post- synaptically inhibiting the running neurons. A method of using such substances permits the preparation of a pharmaceutical composition for treating a patient suffering from symptoms accompanied with unintentional motions such as poriomania and hyperkinesia. In particular, the pharmaceutical composition comprises a member selected from the group consisting of GABA B receptor agonists, GABA A receptor agonists, and GABA A receptor-enhancing substances, or any combination thereof. Moreover, the foregoing problems can likewise be solved by providing a method of using such running neuron-inhibitory substances, which permits the preparation of a pharmaceutical composition for treating a patient suffering from the foregoing symptoms.
Patent CA-2349122-A1 (CA)
Inventor: SCHMIDT HANS-JUERGEN
IPC: B64F5/10
Filed: 2001-05-30
Abstract: When stiffening members, such as stringers and frame members, are welded onto a skin sheet to form an aircraft fuselage shell, a crack originating in the skin sheet tends to propagate through the weld joints into the stiffening members. In order to prevent crack propagation into a stiffening member, the stiffening member is reinforced with a web doubler plate or a tension band made of high strength steel or titanium alloys or fiber-reinforced composites. The doubler plate is riveted or adhesively bonded onto a stiffening member web, or the tension band is crimped into the stiffening member web. The resulting fuselage shell struc-ture has crack stopping properties and thus an increased residual strength, so it can be used with welded joints at all areas of the fuselage shell, including the top and sides as well as the bottom of the fuselage.
Patent CA-2353272-A1 (CA)
Title: Bicycle trailer/hand cart
Inventor: HOAR ANTONY
IPC: B62K27/00
Filed: 2001-07-19
Abstract: A bicycle trailer/hand cart for hitching relatively high on a bicycle, such as to the bicycle seat post or to a rear carrier rack attached to the bicycle, and for transporting a container, is disclosed. The bicycle trailer/hand cart comprises a frame mounted on two wheels. The frame comprises an axle strut having means for attaching a wheel at each end, with a support strut projecting rearward from the axle strut, so that the axle strut and support strut form a "T". A riser is attached to each end of the axle strut and a cross bar is attached to both risers, in a spaced relationship with the axle strut, so that the axle strut, risers and cross bar define a four-sided opening. A draw bar, having a hitch at its proximal end, is attached to the cross bar. In use, a container is transported by resting the bottom of the container on the axle strut and support strut and inserting a forward lower portion of the container into the four-sided opening such that the forward side of the container is abutting the cross bar and the container is interposed between the risers. The frame may also include a cart stand attached to the support strut for supporting the bicycle trailer/hand cart in an upright position when it is not hitched to a bicycle. The hitch may include a flexible belt, or a rigid U-clasp, for encircling the bicycle seat post.
Patent CA-2353596-A1 (CA)
Title: Methode d'immobilisation d'oligonucleotides
Inventor: KITTLE JOSEPH D
IPC: C12N15/87
Filed: 1999-12-03
Abstract: L'invention concerne de nouvelles compositions permettant d'introduire dans une cellule une molécule d'acide nucléique capable de moduler le génotype et le phénotype. Le gène peut être introduit dans un hôte mammalien au moyen d'un vecteur d'expression sous forme d'ADN nu ou conjugué à des supports, en particulier des supports cationiques. La conjugaison s'effectue au moyen d'une fraction contenant de l'éthylène reliée à la molécule d'acide nucléique. Les techniques et compositions selon l'invention s'utilisent pour soigner ou traiter n'importe laquelle d'une série de troubles génétiques.
Patent CA-2353928-A1 (CA)
Inventor: RONDINO ANGELO
IPC: A62C5/00
Filed: 1999-12-17
Abstract: A portable aerosol-type fire-fighting protection device comprises a hollow body (1) which includes in the interior (10) thereof, and communicating with the exterior by way of an opening (3), a chamber (11) for accommodating a solid substance (7) capable of being transformed at a given temperature into an aerosol with flame-extinguishing properties and being discharged as such by way of the opening. A handle (2) is fixed with respect to the body and within its interior there is a space. The accommodating chamber has an electrical resistor (12) for triggering the transformation from solid into aerosol, energised by way of a switch (13) from batteries (14) accommodated in the space (15) in the handle.
Patent CA-2355741-A1 (CA)
Title: High-pressure cleaner
Inventor: NATHAN ROBERT
IPC: B08B3/02
Filed: 1999-10-15
Abstract: A high-pressure cleaner is provided. The cleaner includes a reciprocating pump. A pump head is positioned on a piston guide of the reciprocating pump. At least one piston can be moved in the longitudinal direction of the reciprocating pump. The pump head is produced from plastics and being braced with the reciprocating pump by means of a clamping element. The clamping element has a U-shaped clamping bracket with a base part butting against the pump head and with two legs. The free ends of the legs butt against a metal abutment surface of the piston guide of the reciprocating pump and can be connected releasably to the reciprocating pump.
Patent CA-2356958-A1 (CA)
Title: Tank weigh module with excess motion restraint
Inventor: HANSSON THOMAS W
IPC: G01G23/00
Filed: 2000-01-14
Abstract: A tank weigh module includes a bottom plate that has two lower stop blocks protruding upwardly therefrom, and a top plate that has an upper stop block protruding downwardly therefrom into a space between the two upper stop blocks with a block free play clearance therebetween. A restraining pin is arranged to extend through aligned pin receiving holes in all of the stop blocks.  In the lower stop blocks, the holes provide a tight friction fit for the pin, while the hole in the upper stop block has a larger diameter and provides a pin free play clearance. Motion of the top plate relative to the bottom plate in the back-and-forth Y--direction is limited to the extent of the block free play clearance. Travel of the top plate in the side-to-side X--direction and in the uplift Z-direction is restrained by the extent of the pin free play clearance. Tilting and twisting about the X-, Y-, and Z-axes are also limited by the pin interacting with the blocks and the blocks interacting with each other. A load cell is secured in position between the top and bottom plates by two fixed securing pins and a third removable securing pin attached to the bottom plate, whereby the securing pins are angularly offset by 120° from each other. The weigh module has a simple construction, installation, and servicing, and provides protection against excess uplift, side loading, and tilting while allow complete free floating operation in a normal operating range.