baber/WOPTO huggingface dataset:
Patent SK-280779-B6 (SK)
Title: Condensed benzo compounds, pharmaceutical compositions them containing, and their use
Inventor: MOLTZEN EJNER KNUD
IPC: A61K31/335
Filed: 1993-12-08
Abstract: Fused benzo compounds of formula (I) are provided, wherein A is a 2 to 6 membered hydrocarbon spacer group, B is a polar divalent group selected from a group (a); U is C, N or CH; X is a divalent 3 - 4 membered chain optionally comprising one or more heteroatoms; R1 is an aliphatic hydrocarbon group, arylalkyl or diphenylalkyl; R2 and R3 are hydrogen or alkyl or together form an ethylene or propylene bridge; R4, R5 and R6 are hydrogen or substituents; R7 and R8 are hydrogen or substituents including -COOR9 and -CONR10R11; are 5-HT1A receptor ligands useful in the treatment of CNS disorders. Pharmaceutical compositions comprising the compounds and their use for the manufacture of a pharmaceutical preparation are also provided.
Patent SK-282984-B6 (SK)
Title: Skin-adhering pharmaceutical preparation, in particular transdermal therapeutic system for release of 17-'beta'-estradiol to human organism
Inventor: ASMUSSEN BODO
IPC: A61L15/44
Filed: 1996-12-23
Abstract: Skin-adhering pharmaceutical preparation, in particular a transdermal therapeutic system for the release of the active ingredient 17-'beta'-estradiol. The concentration of the estradiol contained in dissolved form in said preparation is, in all matrix layers and, when an adhesive layer is present, also in the latter, between its saturation concentration in balance with a gaseous phase having less than 10 % relative humidity of air and its saturation concentration in balance with a gaseous phase having greater than 90 % relative humidity of air. Said preparation is characterised in that the amount of estradiol contained therein is at least three times the saturation soluble capacity measured for 95 % relative humidity of air, and the air enclosed in the packaging material is set to a relative humidity of air of between 5 % and less than 0.5 %.
Patent CZ-283926-B6 (CZ)
Title: Clamp of a screw-thread type
Inventor: OETIKER HANS
IPC: F16L33/035
Filed: 1992-07-14
Abstract: A self-retightening screw-type clamp with predetermined adjusting range for a given clamp size, attained by a predetermined number of apertures provided in the inner band portion of a separate band part in conjunction with a sleeve member of predetermined length interposed between the retightening spring and a part-cylindrical tightening member. The full adjusting range of the screw member is made possible by deforming the threads near its free end. Additionally, to facilitate assembly, the inner band portion of the separate band part is provided with a tongue-like extension which is adapted to engage with a latching device formed in the clamping band so as to hold the tongue-like extension of the inner band portion of the separate clamping band part at least close to the outer surface of the clamping band. <IMAGE>
Patent CS-277500-B6 (CS)
Inventor: GALIK DALIBOR
IPC: B23Q3/06
Filed: 1990-07-26
Abstract: Viacpolohovýotočnýupínačje určenýnajmapře
upínanie predmetov opracovávaných z viacerých
stráň, pri jednom upnutí opracovávaného
předmětu a pri jednej pracovnej polohe otočného
bubna. Viacpolohový otočný upínač má
horný i dolný držiak čefuste (1, 2) opatřený
horným a dolným deliacim kolesom (6, 7), uloženým
na hornom a dolnom otočnom čapě (4, 5)
a západkami (8, 12), posuvné uloženými v hornom
i dolnom držiaku čefuste (1, 2), pričom
rozostup a počet drážiek (24) na dolnom deliacom
kolese (7) je zhodný s rozostupom a počtom
drážiek (24) na hornom deliacom kolese (6)
a vzájomná poloha horného deliaceho kolesa (6)
a hornej západky (8) je usporiadaná držiakom
(9) kladky (15) s kladkou (15), posuvné uloženým
v hornom držiaku čefuste (1).
Patent CZ-285466-B6 (CZ)
Title: Circular loom
Inventor: ZIEGLER JOSEF
IPC: D03D37/00
Filed: 1992-04-17
Abstract: 2. The circular loom according to the invention serves for producing tubular fabrics and has an annular frame with an upper ring plate (10) and a lower ring plate (12). Vertically movable healds (32) serve for guiding the warp yarns (36) and are mounted at a uniform distance from one another on at least one circular track (38). For mounting and guiding the healds (32), bearing bores (40) are made in the two ring plates (10,12). The healds (32) have, at their lower ends, cam-follower rollers (42) which run on an associated control disk (44). <IMAGE>
Patent CZ-288585-B6 (CZ)
Title: Playback device and method of playing back a bit stream of a storage medium
Inventor: KEESMAN GERRIT JOHAN
IPC: H04N7/26
Filed: 1995-11-16
Abstract: The invented method is characterized in that a portion of a recorded bit stream is read intermittently in successive reading steps and at a predetermined bit rate from a record medium and is stored in a buffer, to thereby increasing fullness of the buffer, whereby the bit stream stored in the buffer is continuously read of the buffer in conformity with synchronization parameters contained in the bit stream to thereby decreasing fullness of the buffer. At the same time fullness of the buffer is measured and when a predetermined fullness of the buffer is reached, resulting from decrease thereof, a measuring circuit generates a read signal and in response to this read signal another portion of the bit stream recorded in buffer is read, and the process of continuous reading of the bit stream from the buffer and cyclic filling this buffer is cyclically repeated. The device for making the above described method comprises read means (2, 3) for reading a portion of the recorded bit stream at a
Patent CZ-291626-B6 (CZ)
Title: Tricyclic compounds, process of their preparation and use
Inventor: OHKAWA SHIGENORI
IPC: C07D277/62
Filed: 1997-03-05
Abstract: In the present invention there is disclosed a compound of the general formula I, in which Re1 represents an optionally substituted hydrocarbon group, an amine or a heterocyclic group, Re2 represents a hydrogen atom or an optionally substituted hydrocarbon group, Re3 represents a hydrogen atom or an optionally substituted hydrocarbon group or a heterocyclic group, X represents the group CHRe4, NRe4, an oxygen or sulfur atom, wherein Re4 represents a hydrogen atom or an optionally substituted hydrocarbon group, Y represents a carbon atom, the group CH or a nitrogen atom, the A ring represents an optionally substituted five- to seven-membered ring, the B ring denotes an optionally substituted benzene ring and m is the number 1 to 4, or a salt thereof. Disclosed is also a process for preparing the above-described compound, an intermediate for its preparation and a pharmaceutical preparations in which the co  compound is comprised, for treating diseases connected with the action of melatonin in mammals, particularly for treating disorders of endocrine system and nervous system.
Patent CZ-293628-B6 (CZ)
Title: Benzyl(idene)-lactam derivatives, their use and pharmaceutical compositions based thereon
Inventor: HOWARD HARRY R
IPC: C07D217/24
Filed: 1997-02-03
Abstract: In the present invention, there are disclosed benzyl(idene)lactam derivatives of the general formula I wherein Re1 represents a group of the general formulae Ge1, Ge2, Ge3, Ge4 or Ge5, Re2 denotes hydrogen, alkyl, an optionally substituted phenyl or naphthyl, Re3 represents (CHi2)imB wherein m is 0, 1, 2 or 3 and B denotes hydrogen, phenyl, naphthyl or a five- or six-membered heteroaryl containing from one to four hetero atoms in the ring, and wherein each of the foregoing aryl and heteroaryl groups may optionally be substituted; Z is CRe4Re5, wherein Re4 and Re5 are independently selected from hydrogen, alkyl or  trifluoromethyl; or Z may be one of the aryl or heteroaryl groups referred to in the definition of B above; X denotes hydrogen, a halogen, cyano, alkyl, hydroxy, trifluoromethyl, alkoxy, -SOig-alkyl, wherein g is zero one or two, CO2Re10 or  CONRe11Re12; n is one, two, three or four; with the proviso that n must be one when Z is a heteroaryl group; or pharmaceutically acceptable salts thereof. These compounds are selective antagonists or agonists of 5-HTi1A- and/or 5-HTi1D receptors and thus are useful as psychotherapeutic agents.
Patent CZ-288829-B6 (CZ)
Title: Preparation for treating hypersensitive teeth
Inventor: MARKOWITZ KENNETH
IPC: A61K8/40
Filed: 1996-04-10
Abstract: The present invention relates to a preparation for treating hypersensitive teeth, whereby this preparation is characterized in that it contains hectorite clay, particularly laponite clay.
Patent CZ-296436-B6 (CZ)
Title: Detergent surfactant composition
Inventor: CONNOR DANIEL STEDMAN
IPC: C11D1/72
Filed: 1997-04-16
Abstract: In the present invention, there are disclosed primary surfactant compositions derived from mid-chain branched primary alkyl hydrophobic groups and hydrophilic groups. The present invention also relates to mixtures of mid-chain branched surfactants useful in laundry and cleaning compositions, especially granular and liquid detergent compositions.
Patent CZ-289892-B6 (CZ)
Title: Low-dust granules of plastic additives, process of their preparation and their use for stabilizing organic polymers
Inventor: THIBAUT DANIEL
IPC: C08K3/22
Filed: 1995-12-27
Abstract: In the present invention there are disclosed low-dust granules of plastic additives, comprising at least 10 percent by weight of calcium stearate, whereby the water content of the calcium stearate is less than 2 percent by weight, having a particle size distribution, in accordance with ISO 3435, of from 1 mm to 10 mm, a loose bulk density of greater than 400 g/l and a flowability in accordance with DIN 53492 of less than 15 s (tR25). In the present invention there is also claimed a process for their production, and the use of these granules for the stabilization of organic polymers.
Patent SK-280899-B6 (SK)
Title: Use of piperidine derivatives, piperidine derivatives, pharmaceutical preparations
Inventor: MOLTZEN EJNER K
IPC: C07D491/107
Filed: 1992-06-12
Abstract: Use of piperidine derivatives for the production of pharmaceutical preparations that are useful for the treatment of anxiety, psychosis, epilepsy, convulsion, movement disorders, motor disturbances, amnesia, cerebrovascular diseases, senile dementia of the Alzheimer type or Parkinson's disease. Piperidine compounds having the general formula (I) wherein general substituents R1 to R7 and Z1 to Z3 are defined in the claims; pharmaceutical preparations containing the said piperidine derivatives.
Patent SK-277686-B6 (SK)
Title: Universal air valve with regulation of inlets
Inventor: HAISMAN JAROSLAV
IPC: F16K31/122
Filed: 1990-05-18
Abstract: Subject matter of this invention solves the mechanism and the construction of an air servo-operated valve, which can have several functions. The universal air valve with a regulation of inlets consists of an air valve with a switching over air drive. A bottom part of roller (6) of the air drive is revolving connected with a body (1) of valve and top part of roller (6) of the air drive is firm joined with an operating microvalve (19). A bottom valve seat (5) and a top valve seat (4) are revolving located in the body (1) of valve. In the top part of body (1) of valve is the first inlet hole (15) and a left connecting channel (12). In the middle part of the body (1) of valve is created the second inlet hole (16) and the third inlet hole (17) is connected by right connecting channel (13) created in the roller (6) of air drive with the operating microvalve (19).
Patent SK-278320-B6 (SK)
Title: Process for producing of cyclosporine a
Inventor: GIRON DANIELLE
IPC: C07K7/64
Filed: 1988-12-20
Abstract: This solution is dealing with a production of cyclosporine A in the orthorhombic form called (P212121) with a crystalline lattice, where the dimension of a is equal 12,5 Å, the dimension of b is equal to 22,9 Å, the dimension of c is equal to 28,4 Å and the volume closed to the asymmetric unit is equal to 2027 Å3 this procedure is based on that, the cyclosporine A is resolved in the environment created with the use of a solvent containing polymeric ether with a molecular weight of 200, at the temperature of 40 Celsius degrees at least and the solution containing 5 up to 60 weight percent of cyclosporine A, related to the total weight of the solution, cyclosporine A is crystallising of this solvent and the determined orthorhombic form is created and the gained product is isolated. The substance gained based on this procedure can be used in all of the applications with cyclosporine A, for local application on the skin, in the eye or for internal joint application.
Patent CZ-305066-B6 (CZ)
Title: Process for preparing (3R, 4S)-l-(4-fiuorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3- hydroxypropyl)]-4-(4-hydroxyphenyl)-2-azetidinone
Inventor: ŠTĚPÁNKOVÁ HANA
IPC: C07F7/18
Filed: 2008-02-25
Abstract: In the present invention, there is disclosed a process for preparing (S)-alcohol-oxazolidides of the general formula II, wherein PG represents hydrogen or a hydroxyl protecting group, such as trimethylsilyl, tert-butyldimethylsilyl, benzyloxycarbonyl, tert-butoxycarbonyl, benzyl, benzhydryl or trityl wherein the preparation process is characterized in that a ketal-oxazolidide of the general formula III, in which PG is the same as indicated above and R denotes alkyl containing 1 to 4 carbon atoms linear or branched such as methyl, ethyl, isopropyl or butyl, or R+R together represent a bivalent alkyl being optionally substituted with 1 to 2 alkyl groups such as 1,2-ethylene, 1,2-propylene, 1,2-butylene, 1,3-propylene or 2,2-dimethyl-1,3-propylene, is protected by the reaction of acidic agents in a mixture of water and a water-miscible solvent at a temperature ranging from 0 to 100 degC (stage A), and the so obtained ketone-oxazolidide of the general formula IV, in which PG is as defined above, is reduced by asymmetric agents in an inert organic solvent in the temperature range of -30 to +40 degC (stage B).
Patent CZ-293387-B6 (CZ)
Title: Compacted disintegrant granulate for tablets, process for its preparation and use
Inventor: HARTAN HANS-GEORG DR
IPC: C11D17/06
Filed: 2000-03-28
Abstract: In the present invention, there is disclosed a compacted granulate containing water-swellable cellulose and cellulose derivatives optionally starch derivatives, polymers and copolymers of (meth)acrylic acid and/or salts thereof, and optionally one or several liquid surfactants, wherein the granulate has a water content of from 2 to 8 percent by weight. Disclosed is also the use of the granulate as a disintegrating agent for detergent tablets, cleaner tablets, water-softening tablets, and stain removing salt tablets, as well as a process for preparing the above-described compacted granulate by mixing components thereof, granulation and molding.
Patent SK-287659-B6 (SK)
Title: Apparatus and method for micron and submicron particle formation, nozzles for carrying a solution into the vessel for micron and submicron particle formation
Inventor: DEL RE GIOVANNI
IPC: C12N9/00
Filed: 2002-02-26
Abstract: Generating equipment sub micrometer and submicron particulate matter using the GAS process, comprising a container (22) to create particles and means to implement solution of the substance and the supercritical fluid into the container (22) to produce particles, which comprises the nozzle (27) with a central mouth (39), which serves to conduct current solution, as several separate external mouths (41), which serve to drive with clean supercritical fluid or supercritical fluid stream, mixed with the modifier so that the solvent is extracted from a solution of supercritical fluid and precipitation occurs sub micrometer and submicron particles. It also describes a process carried out with such a device.
Patent SK-286683-B6 (SK)
Title: CD19xCD3 specific polypeptides and uses thereof
Inventor: DORKEN BERND
IPC: A61K35/76
Filed: 1999-04-21
Abstract: Described are single-chain multifunctional polypeptides comprising at least two binding sites specific for the CD19 and CD3 antigens. Further provided are polypeptides, wherein the above-described polypeptide comprises at least one further domain, preferably of pre-determined function. Furthermore, polynucleotides encoding said polypeptides as well as to vectors comprising said polynucleotides and host cells transformed therewith and their use in the production of said polypeptides are described. In addition, compositions, preferably pharmaceutical and diagnostic compositions are provided comprising any of the afore-described polypeptides, polynucleotides or vectors and also the use of the afore-mentioned polypeptides, polynucleotides and vectors for the preparation of pharmaceutical compositions for immunotherapy, preferably against B-cell malignancies such as non-Hodgkin lymphoma.
Patent BR-0308178-B8 (BR)
Inventor: PERVAN DARKO
IPC: B44C5/04
Filed: 2003-03-20
Abstract: The system has a surface layer (31) on an upper side of a core (30) and connecting unit (9,10,8,12) placed at the adjoining edges to connect the floorboards with each other. The surface layer has an upper layer (35) and an underlying layer (36a) such that an edge has a surface having the underlying layer parallel to a horizontal plane that is formed by the parts of the surface layer closest to the edges. An independent claim is also included for a method of making a decorative joint portion on a floor board.
Patent EP-1795103-B8 (EP)
Inventor: SCHIEMANN JUERGEN
IPC: A47L9/24
Filed: 2006-09-19
Granted: 2012-06-06
Abstract: The telescopic dust cleaner suction pipe (10) consists of one outer pipe (11) and an axially slidable inner pipe (12) that has lock recesses (15) along the coating line from the inner pipe outer coating surface (14) to the pipe central axis (M) having inward projecting locking recesses (15). The locking recesses operate with at least one adjustment body (24) that alternately locks or releases on the outer pipe's held adjustment device (18). The outer pipe has a second locking recess (16).
Patent BR-PI0403964-B8 (BR)
Title: formulações líquidas estáveis, artigo manufaturado e uso dessas formulações para o tratamento de disfunção mediada por ige
Inventor: JUN LIU
IPC: A61K47/26
Filed: 2004-03-29
Abstract: formulações líquidas estáveis, artigo manufaturado e métodos de tratamento de disfunção mediada por ige o presente pedido refere-se a formulações de proteína e anticorpo altamente concentradas com viscosidade reduzida que são estáveis, relativamente isotônicas e são de baixa turbidez. as formulações são particularmente apropriadas para administração subcutânea. o pedido descreve ainda artigos manufaturados que contêm essas formulações e método de sua utilização para o tratamento de disfunções que podem ser tratadas pelo anticorpo ou proteína formulada.
Patent BR-PI0515289-B8 (BR)
Title: dispositivos de liberação nasal
Inventor: COLIN DAVID SHELDRAKE
IPC: A61M15/00
Filed: 2005-09-15
Abstract: dispositivos de liberação nasal um dispositivo de liberação nasal e método de liberação de substância a uma cavidade nasal de um sujeito, o dispositivo de liberação compreendendo: uma unidade de recebimento de recipiente compreendendo uma câmara de recipiente para receber um recipiente contendo substância que contém substância a ser liberada à cavidade nasal do sujeito, a câmara de recipiente incluindo uma entrada e uma saída; uma unidade de peça que se adapta ao nariz incluindo uma peça que se adapta ao nariz para se ajustar a uma cavidade nasal do sujeito e estando em comunicação de fluido com a saída da câmara de recipiente; uma unidade de boquim incluindo um boquim em comunicação de fluido com a entrada da câmara de recipiente e através da qual o sujeito em uso exala, tal como para inserir substância a partir do recipiente e liberar a mesma através da peça que se adapta ao nariz; e dispositivo de suavização de umidade para suavizar um efeito de umidade em uma respiração exalada na entrada de substância a partir do recipiente, que dispositivos são fornecidos, por exemplo, através de fornecer o recipiente em um membro contendo recipiente substituível, através de uma válvula sensível a pressão que normalmente fecha a conexão de fluido entre a câmara de recipiente e a boquim, e um regulador de temperatura fluxo acima da câmara de recipiente.
Patent AU-2008238324-B8 (AU)
Title: Method for producing storage-stable solutions from pelargonium extracts
Inventor: HAUER HERMANN
IPC: A61K47/00
Filed: 2008-04-04
Granted: 2012-10-11
Abstract: The invention relates to a method for producing storage-stable solutions from pelargonium extracts, characterized in that the oxygen quantity at atmospheric pressure in the head space of the package used to store the solution of pelargonium extract is reduced to a maximum of 0.025 parts by volume (preferably 0.015 parts by volume, especially preferably 0.005 parts by volume) per volume part of the solution, wherein the content of proanthocyanidines and 2H-1-benzopyran-2-ones after 9 months of storage at 25°C and a relative humidity of 60% is reduced by a maximum of 10 weight % each (preferably a maximum of 7 weight %, especially preferably a maximum of 5 weight %, particularly a maximum of 3 weight %).
Patent AU-2017268310-B8 (AU)
Title: Spray chambers and methods of using them
Inventor: Stephan Chady
IPC: H05H1/42
Filed: 2017-05-17
Granted: 2022-12-08
Abstract: Devices, systems and methods including a spray chamber are described. In certain examples, the spray chamber may be configured with an outer chamber configured to provide tangential gas flows. In other instances, an inner tube can be positioned within the outer chamber and may comprise a plurality of microchannels. In some examples, the outer chamber may comprise dual gas inlet ports. In some instances, the spray chamber may be configured to provide tangential gas flow and laminar gas flows to prevent droplet formation on surfaces of the spray chamber. Optical emission devices, optical absorption devices and mass spectrometers using the spray chamber are also described.
Patent BR-112013014851-B8 (BR)
Title: Unidade de distribuição de combustível
Inventor: HANS-GUENTER BENNER
IPC: F02M37/14
Filed: 2011-12-13
Abstract: UNIDADE DE DISTRIBUIÇÃO DE COMBUSTÍVEL. A presente invenção refere-se a uma unidade de distribuição de combustível (4) em um tanque de combustível (1) de veículo motor, composto de um caldeirão de sobretensão (5), uma bomba de combustível (6) que é disposta no dito caldeirão de sobretensão e serve para distribuir combustível para fora do caldeirão de sobretensão (5) para um motor de combustão inteiro do veículo a motor, um prendedor de bomba (8) para fixar a bomba de combustível (6) no caldeirão de sobretensão (5), e um sensor de nível de preenchimento (13) para determinar o nível de preenchimento do tanque de combustível (1). O sensor do nível de combustível (13) é disposto no prendedor da bomba (8).
Patent BR-112015001587-B8 (BR)
Title: Método de ensaio de pcr para determinação da zigosidade de um gene rf4 em uma planta de milho
Inventor: RUIHUA REN
IPC: C12Q1/68
Filed: 2013-07-23
Abstract: MÉTODO DE ENSAIO DE PCR PARA DETERMINAR A ZIGOSIDADE DE ESTÁGIO FINAL DO GENE RF4 NO MILHO, E KIT DE DETECÇÃO DO DNA. Um método é fornecido para determinar a zigosidade de um gene RF4 em uma planta de milho. Um método pode incluir a execução de um primeiro ensaio de PCR, um segundo ensaio de PCR, sondas de quantificação utilizadas no primeiro e segundo ensaios de PCR, e comparar as sondas quantificadas para determinar a zigosidade.
Patent BR-112016020496-B8 (BR)
Title: Produto agronômico revestido com um produto fertilizante e método para melhorar o crescimento inicial de uma planta
Inventor: MARK GOODWIN
IPC: C05G3/00
Filed: 2014-07-22
Abstract: FERTILIZANTE À BASE DE FÓSFORO ZINCO E MANGANÊS Um produto fertilizante iniciador que combina manganês com P e Zn cria uma sinergia anteriormente desconhecida no crescimento inicial das plantas e saúde das plantas.