baber/WOPTO huggingface dataset:
Patent CR-20110106-A (CR)
Title: Composición farmacéutica para el uso en el tratamiento de infecciones de transmisión sexual
Inventor: GARCÍA SALGADO LÓPEZ ANGÉLICA
IPC: A61K31/4168
Filed: 2011-02-25
Abstract: La presente invención se refiere a una composición farmacéutica oral sólida que comprende fluconazol, tinidazol y clindamicina o una sal farmacéuticamente aceptable de los mismos, donde el contenido de excipientes farmacéuticamente aceptables es significativamente menor que el contenido que los principios activos, el uso de dicha composición para Ia administración oral con actividad terapéutica para el tratamiento de infecciones de transmisión sexual.
Patent CR-20120491-A (CR)
Title: Proteinas de unión a antigeno especificas para el componente amiloide serico p
Inventor: BHINDER TEJINDER KAUR
IPC: A61K39/395
Filed: 2012-09-27
Abstract: La presente invención se refiere a proteínas de unión a antígeno, tales como anticuerpos, que se unen al componente amiloide sérico P (SAP), a polinucleótidos que codifican dichas proteínas de unión a antígeno, a composiciones farmacéuticas que comprenden dichas proteínas de unión a antígeno y a procedimientos de fabricación. La presente invención también se refiere al uso de dichas proteínas de unión a antígeno en el tratamiento o rpofilaxis de enfermedades asociadas con deposición amiloide que incluyen amiloidosis sistémica, amiloidosis local, enfermedad de Alzheimer y diabetes de tipo 2.
Patent CR-20140587-A (CR)
Title: Metodo para producir iduronato-2-sulfatasa recombinante
Inventor: ZHANG CHUN
IPC: C12P21/02
Filed: 2014-12-17
Abstract: La presente invención proporciona entre otras cosas, métodos y composiciones para la producción a gran escala de proteína I2S recombinante usando cultivo de suspención de células de mamífero en medio libre de suero.
Patent CR-20150628-A (CR)
Title: Derivados de la pirazolopirrolidina y su uso en el tratamiento de enfermedades
Inventor: BLANK JUTTA
IPC: C07D487/04
Filed: 2015-11-27
Abstract: La presente invención proporciona un compuesto de la fórmula (I) o una sal farmacéuticamente aceptable del mismo y un método para fabricar los compuesto de la invención, y sus usos terapéuticos. La presente invención además proporciona una combinación de agentes farmacológicamente activos y una composición farmacéutica.
Patent CR-20190479-A (CR)
Title: Sustained release delivery systems comprising traceless linkers
Inventor: APRIL MYRIAM
IPC: A61P27/02
Filed: 2018-04-19
Abstract: Described herein are drug delivery systems for delivering biologically active agents comprising primary or secondary amines, or a ring nitrogen atom of an azaheteroaryl ring, pharmaceutically acceptable salts thereof, drug delivery reagents related thereto, pharmaceutical compositions comprising the drug delivery systems, and the use of the drug delivery systems as sustained release therapeutics.Se describen sistemas de administración de fármacos para administrar agentes biológicamente activos que comprenden aminas primarias o secundarias, o un átomo de nitrógeno anular de un anillo de azaheteroarilo, sales farmacéuticamente aceptables de los mismos, reactivos de administración de fármacos relacionados con los mismos, composiciones farmacéuticas que comprenden los sistemas de administración de fármacos y el uso de los sistemas de administración de fármacos como terapias de liberación sostenida.
Patent CR-20230212-A (CR)
Title: System for removing particulates from liquid
Inventor: HARTWELL ERIK KARL
IPC: E03F5/14
Filed: 2021-11-12
Abstract: The embodiments of the present disclosure provide a system for removing particulates from liquid. The system may comprise a base 210, a tubular body 480 extending upwardly from the base, a liquid quality device 100 located above the base, a sump region 240 located between the base and the liquid quality device, and a plurality of drag-inducing portions 450 positioned in the sump region and projecting inwardly toward a central axis of the sump region. The tubular body may comprise an inlet and an outlet. The plurality of drag-inducing portions may comprise a first set of drag-inducing portions 450a, a second set of drag-inducing portions 450b, a third set of drag-inducing portions 450c, and a fourth set of drag-inducing portions. The first, second, third, and fourth sets of drag-inducing portions may be positioned equidistant from each other and at a same height around a perimeter of the sump region.
Patent EC-SP066431-A (EC)
Title: Moléculas de unión de nogo-a y uso farmacéutico de las mismas
Inventor: BARSKE CARMEN
IPC: C07K16/18
Filed: 2006-03-17
Abstract: La presente invención proporciona una molécula de unión que es capaz de unirse al polipéptido NogoA humano o NiG humano o NiG-D20 humano o NogoA_342-357 humano, con una constante de disociación de <1000 nM, un polipéptido que codifica dicha molécula de unión; un vector de expresión que comprende dicho polinucleótido; un sistema de expresión que comprende un polinucleótido capaz de producir una molécula de unión; una célula huésped aislada que comprende un sistema de expresión según se define anteriormente; el uso de tal molécula de unión como un farmacéutico, especialmente en el tratamiento de reparación de nervios; una composición farmacéutica que comprende dicha molécula de unión; y un método de tratamiento de enfermedades asociadas con la reparación de nervios.
Patent EC-SP088194-A (EC)
Title: Antagonistas de cgrp seleccionados, procedimientos para su preparación, así como su uso como medicamentos
Inventor: STENKAMP DIRK
IPC: C07D401/14
Filed: 2008-02-15
Abstract: Objeto de la presente invención son los antagonistas de CGRP de la fórmula general I (I)en donde R1, R2, R3 y R4 se definen como en la reivindicación 1, sus tautómeros, sus isómeros, sus diastereoisómeros, sus enantiómeros, sus hidratos, sus mezclas y sus sales, así como los hidratos de las sales, en especial sus sales fisiológicamente tolerables con ácidos o bases inorgánicos u orgánicos, así como aquellos compuestos de la fórmula general I, en los que uno o varios átomos de hidrógeno se intercambiaron por deuterio, medicamentos que contienen estos compuestos, su uso y procedimientos para su preparación.
Patent EC-SP088567-A (EC)
Title: Composiciones farmaceuticas que comprenden derivados de esteroides sintéticos, minerales y el metabolito activo de la vitamina d, 1,25(oh)2d3 (calcitriol) para la prevención y tratamiento de la osteoporosis y el control de los síntomas de la menopaus
Inventor: SANTOS MURILLO JOSEFINA
IPC: A61K31/57
Filed: 2008-06-20
Abstract: La presente invención esta relacionada con la industria farmacéutica en general y con la industria farmacéutica preparadora de medicamentos para el control de osteoporosis, en particular. Más específicamente se trata de una composición formada por una combinación de un derivado de esteroides sintéticos como lo es la Tibolona, minerales con el calcio y el metabolito activo de la vitamina D 1,25 (OH)2 (calcitriol), para la prevención y tratamiento de la Osteoporosis. Una de las ventajas de la presente composición con respectos de las del estado de la técnica es que permite usar, con los mismos resultados, una cantidad menor de los componentes que cuando son consumidos de manera separada o con unos resultados mejores una cantidad igual que cuando son consumido por separados. Dicha composición consiste en: una combinación sinérgica de un esteroide sintético, minerales y el metabolito activo de la vitamina D, 1,25(OH)2 D3 (calcitriol) para la prevención y tratamiento de la Osteoporosis.
Patent EC-SP941103-A (EC)
Title: Suspension libre de disolvente y soluble en aceites de polimeros reductores de la resistencia al avance
Inventor: SMITH KEN W
IPC: B05D7/00
Filed: 1994-06-14
Abstract: Se describe una suspensión reductora de la resistencia al avance, soluble en hidrocarburos, así como un proceso para su obtención. El proceso está dirigido hacia la producción de un producto reductor de la resistencia al avance que es fácilmente transportable, no peligroso, fácilmente manipulable y, al mismo tiempo, proporciona un incremento importante de la capacidad de reducción de la resistencia al avance en relación con los productos comerciales ahora existentes. Con preferencia, la suspensión está prácticamente libre de disolvente.
Patent EC-SP961730-A (EC)
Title: Articulo absorbente
Inventor: INGEMAR FERNFORS
IPC: A61F13/15
Filed: 1996-04-23
Abstract: El invento se refiere a un artículo absorbente tal como unos pantalones absorbentes, una toalla sanitaria, un artículo de protección para la incontinencia o algo semejante, con una forma sustancialmente alargada y que presente una región frontal de la cintura, una región trasera de la cintura y en medio de estas una región de entrepiernas teniendo dos porciones de los bordes de las piernas. El artículo contiene una capa interna permeable a los fluidos y un núcleo absorbente encerrado entre ellas. El artículo también contiene elementos elásticos, los cuales están dispuestos a lo largo de cuatro diferentes vías. Un segmento de cada vía sigue por lo menos una porción del borde de la pierna y las vías juntas encierran una región recolectora colocada entre las porciones de los bordes de las piernas del artículo, cuya región bajo la influencia de los elementos elásticos se abulta y forma una depresión recolectora de fluidos.
Patent FI-20000700-A (FI)
Inventor: RANTA JUKKA
IPC: H04B1/707
Filed: 2000-03-24
Abstract: A method of operating a mobile station in a WCDMA system. The mobile station has a rake receiver (90) having a plurality of demodulator fingers (71,72,73). One of the demodulator fingers monitors a neighbouring cell and other demodulator fingers monitor an assigned cell. When the mobile station is in an idle mode, if it is stationary, activity of the demodulator is reduced by switching off the demodulator finger which monitors the neighbouring cell. <IMAGE>
Patent FI-20022265-A (FI)
Inventor: VEIKONHEIMO TOMI
IPC: B63H1/28
Filed: 2002-12-20
Abstract: In a counter rotating propulsion system (CRP), whereby the aft propeller ( 22 ) and the forward propeller ( 6 ) have opposite directions of rotating and the aft and forward propellers are arranged against each other, the forward propeller is provided with a hubcap ( 30 ), wherein at least two equally distributed flow plates ( 28 ) are arranged on the cap ( 30 ) and the flow plates ( 28 ) are radially projecting from the cap ( 30 ).
Patent FI-20055485-A (FI)
Inventor: PIHLAJAMAA JOUKO
IPC: H02B7/00
Filed: 2005-09-09
Abstract: The invention relates to an arrangement and a protective element for reducing magnetic fields. The arrangement comprises a base (6), a frame part (4) placed onto the base, fittings (5) fixed to the frame part and a housing part (3) of the electrical cabinet. The arrangement is characterized in that above the fittings, between the electrical cabinet housing part and the fittings, there is provided a protective element (10) reducing the magnetic field. The protective element is preferably made of aluminium and it comprises a background portion (11) and a horizontal upper portion (24) provided with a downward oriented portion (22).
Patent FR-1602169-A (FR)
Title: Pressure casting furnace having an open - crucible
IPC: B22D18/04
Filed: 1968-12-27
Granted: 1970-10-19
Abstract: The furnace comprises a crucible in a pressurisable chamber, from which the burner or burners heating the crucible can be withdrawn. The burner passage orifice can be tightly closed when the burners are withdrawn, and the combustion gas exhaust orifice in the furnace space is tightly closed when the burners are brought into the rest position. Compressed air is introduced into the furnace chamber and molten metal flows through an injection tube into one or more matrices when the furnace is pressurised.
Patent GB-1019664-A (GB)
IPC: G03C1/79
Abstract: 1,019,664. Coated paper. EASTMAN KODAK CO. Sept. 18, 1962 [Sept. 18, 1961], No. 35568/62. Heading B2E. [Also in Division G2] A polymer-coated paper comprises a paper base, a synthetic polymer coating on the paper, and an antistatic agent in the body of the paper, on the surface thereof and between the paper and the polymer coating, or on the other surface of the paper. The polymer coating may be on both sides of the paper, the antistatic agent being in the body of the paper or on a surface thereof and between the paper and one of the polymer coatings. The polymercoated paper may be produced by impregnating or coating the paper with the antistatic agent and then coating the paper on one side at least with a layer of synthetic polymer. The polymer may be a poly-alpha-olefin wherein the olefin contains 2-10 carbon atoms, e.g. polyethylene, polypropylene, or a copolymer of ethylene and propylene, polyester, polyamide, polyacetal, polycarbonate, or a cellulose derivative e.g. cellulose ester or ether. The polymer coating may be from 0À4-0À6 mils thick. The antistatic agent may be the sodium salt of naphthalene sulphonic acid, which may be present from 0À6-1À5 pounds per 1000 sq. feet of paper, sodium sulphate, salts of organic compounds, such as the alkali metal and ammonium salts of the condensation products of an aldehyde e.g. formaldehyde, with naphthalene sulphonic acids; triethanolamine oleate and stearate, polyalkylene polyamine derivatives, oxyalkylene amine derivatives of phosphorus, polyacrylyoxyalkyl trialkyl ammonium alkyl sulphate salts, diethanolamine salts of phosphate esters, hydroxyethers, polyhydroxy alcohols, or carbon black. A light sensitive photographic silver halide emulsion layer may be applied to the, or one of the, polymer coatings to produce a photographic paper. Prior to the application of the emulsion layer, the polymer coating may be treated, for example, by electron bombardment, flame treatment, oxidation using sulphuric acid-bichromate solution, peroxides and the like; by subbing using colloidal silica or zirconia; or by incorporating silica of larger than colloidal size in the polymer surface.
Patent GB-1050355-A (GB)
IPC: B60R1/06
Abstract: 1,050,355. Rear view mirrors. Y. J. TALBOT. Feb. 21, 1964 [Sept. 6, 1963], No. 7288/64. Heading B7J. An external rear-view mirror for a motor vehicle comprises an approximately conical housing 3, a mirror head 5 adjustable in the housing by a screw 13, a centring disc 16 and a resilient tongue 18 on the disc, and a hollow foot 2, the housing 3 being secured on the foot 2 and vehicle body 1 by eye-bolts 7, the cranked eye-ends 20 of which are secured to the body 1 by self-tapping screws 6. The cranked eyeends 20 of the bolts permit of limited adjustment of the housing 3 and the foot 2 relative to the longitudinal axis of the vehicle. Shimplates 8 and 9 are provided between the foot and the housing and within the housing respectively, and an elastic packing member 12 is provided between the foot and the body 1. In another embodiment a hollow mounting base is provided between the foot and the vehicle body. Drilling templates for the body holes to receive the screws 6, are described with reference to Figs. 4 and 5 (not shown).
Patent GB-1095583-A (GB)
IPC: F02B3/06
Abstract: 1,095,583. Combustion chambers. DAIMLER-BENZ A.G. March 18, 1966 [March 20, 1965], No. 12109/66. Heading F1B. A combustion chamber 5 comprises a lower portion 12 connected through a shoulder 6 to a wider diameter upper portion 7, the fuel being injected from a pintle type nozzle through a tangential channel 9 on to the upper part 7 of the chamber wall. In Fig. 3 (not shown) the fuel is injected through a passage 14 in the piston tangential to the combustion chamber 5a.
Patent GB-1145416-A (GB)
Abstract: 1,145,416. Carbon disulphide. GLANZSTOFF A.G. 27 Feb., 1968 [2 March, 1967], No. 9385/68. Heading C1A. Carbon disulphide and hydrogen sulphide (as a by-product) are produced by passing trithiane and sulphur vapours through a reaction tube in unidirectional flow; the reaction tube being heated to 450‹ to 1000‹ C., preferably 450‹ to 650‹ C.
Patent GB-1226316-A (GB)
IPC: D01D5/30
Filed: 1969-09-22
Abstract: 1,226,316. Spun yarns. CHISSO CORP. 22 Sept., 1969, No. 46498/69. Headings D1F and D1W. A method for the production of bulky spun yarns comprises making tows of polypropylene containing conjugate filaments which have been stretched at a temperature below 60‹C, into slivers, spinning the slivers into spun yarn and subjecting the spun yarns, which may be in the form of knitted or woven fabric, to a heat treatment at a temperature at least 20‹C higher than the stretching temperature. The polypropylene-containing conjugate filaments may be the only component of the spun yarn, or the yarn may be formed from a blend of slivers. In the case of a blend, it is preferred that at least 40% is the polyproylene-containing conjugate filament. The yarns produced have good stretch and high bulk. The spun yarn may be heat treated by means of dry heat, hot water or steam, this heat treatment developing crimps in the filaments.
Patent GB-1229344-A (GB)
IPC: C08J9/34
Filed: 1969-09-03
Abstract: 1,229,344. Boots &c. SEMPERIT A.G. 3 Sept., 1969 [5 Sept., 1968], No. 43495/69. Heading A3B. A heel 1 consists of an insert 2 made of a rigid foam and an outer layer 3 made of a semi-rigid, closed-cell foamed polyurethane. The insert 2 is preferably rigid foamed polyurethane and may be formed in a single piece as shown in in several pieces (not shown) separated by ribs formed in the material of the outer layer 3. The heel is made by placing the insert 2 in a mould (not shown) and injecting the material to form the outer layer 3. The heel may be bonnded to the bottom of a lasted shoe during the moulding operation.
Patent GB-1229680-A (GB)
IPC: H04R9/02
Filed: 1968-11-27
Abstract: 1,229,680. Reverberation systems; moving coil transducer. AKUSTISCHE U KINOGERATE G.m.b.H. 27 Nov., 1968 [29 Nov., 1967], No. 56219/68. Headings H4J and H4R. The transducer 2 for a reverberation device includes a moving coil 5 coupled to an helical spring 1 and rotatable in the air gap of a magnetic circuit 3, the dimensions of the moving coil are such that its moment of inertia is as large as the moment of inertia of one spring turn and its effective length is as large as the diameter of the spring and the distance between opposite parts of the coil is two-thirds the diameter of the spring. The coil is wound on a frame and its ends are connected by adhesive to support 8 and spring 1, the adhesive, e.g. synthetic resin, providing a strengthening web. The coil rotates around core member 4 and a bearing 9 is provided between the coil and spring 1. The magnetic circuit may be provided with one or two magnets and in the latter case core 4 forms part of the tongue lying between the magnets, Fig. 4 (not shown).
Patent GB-1230614-A (GB)
IPC: C07D487/04
Filed: 1968-07-17
Abstract: 1,230,614. Ergot alkaloids and intermediates therefor. SANDOZ Ltd. 17 July, 1968 [2 Aug., 1967], No. 33952/68. Heading C2C. Novel salts of compounds I, wherein R signifies isopropyl, isobutyl or benzyl are obtained by heating an azide II (prepared from the corresponding acid chloride utilizing, e.g., sodium azide; the acid chloride is derived from the corresponding free acid-this may contain water of crystallization-which is itself derived from the corresponding ethyl ester by hydrolysis) in an inert solvent with an aqueous acid or by reacting said azide with benzyl alcohol to afford the corresponding urethane and subsequently removing the benzyloxycarbonyl group hydrogenolytically in acid solution; the salts of compounds I may contain tetrahydrofuran of crystallization. Ergocristine, ergocristinine, ergocryptine, ergocryptinine, ergocornine, ergocorninine and the 9,10-dihydro analogues thereof are prepared by reacting the appropriate compound I (or a salt thereof) with lysergic (or 9,10-dihydrolysergic) acid chloride hydrochloride. The above ethyl esters are prepared by removing the benzyl group hydrogenolytically from compounds VI whereby spontaneous stereospecific ring closure occurs; compounds VI are obtained by isopropylating 2-benzyloxymalonic acid diethyl ester or by benzylating 2-hydroxy- 2-isopropyl-malonic acid diethyl ester, selectively saponifying the resulting 2-benzyloxy-2- isopropylmalonic acid diethyl ester to give 2- benzyloxy-2-isopropylmalonic acid monoethyl ester (the potassium salts are also described), converting this into the corresponding acid chloride monoethyl ester and condensing this with a compound V. The azide II wherein R is an isopropyl group when subjected to a high vacuum at 25‹ C. affords the corresponding isocyanate. Diastereoisomers of certain of the above compounds may be separated if desired. Reference has been directed by the Comptroller to Specification 1,011,113.
Patent GB-1232104-A (GB)
IPC: G01N30/46
Filed: 1968-07-08
Abstract: 1,232,104. Thin layer chromatography. DEUTSCHE AKADEMIE DER WISSENSCHAFTEN ZU BERLIN. 8 July, 1968, No. 32482/68. Heading B1X. A cylindrical chamber 1 for thin layer chromatography element 6 comprises bulbous ground glass joint end caps 14, 15 the latter adapted to contain mobile phas 5, and having gas inlet 17, and the latter having gas outlet hole 18 which can be rotated into registration with a corresponding hole in chamber 1; thin layer element 6 is positioned and supported by spacing elements 8. The gas inlets and outlets enable the chromatographic separation process to proceed in any desired atmosphere, and the chamber is well adapted to be used as one of a series held in a tiltable frame (see Fig. 2, not shown). A number of variants of such a chamber are described (see Figs. 3-8 and 10), as well as particular embodiment of element supports for use therein (see Figs. 9, 9a, and 12-16, not shown).
Patent GB-1252329-A (GB)
IPC: A61K31/19
Filed: 1969-05-06
Abstract: 1,252,329. Derivatives of anilinophenylaliphatic acids. SUMITOMO CHEMICAL CO. Ltd. 6 May, 1969 [8 May, 1968; 13 May, 1968; 15 May, 1968], No. 23057/69. Heading C2C. Derivatives of o-anilinophenylaliphatic acids of the Formula I wherein A is an unsubstituted or C 1-3  alkylsubstituted ethylene or vinylene chain, R, R<SP>1</SP>, R<SP>2</SP> and R<SP>3</SP> are each H 1  halogen, C 1-3  alkyl, C 1-3  alkoxy or halogen-substituted C 1-3  alkyl and R<SP>4</SP> is OH or C 1-4  alkoxy and their salts, the compounds of the above Formula I in which A is an unsubstituted or C 1-3  alkyl-substituted ethylene chain being novel, are prepared either by reacting a compound of the Formula III above with a compound of Formula R<SP>4</SP>H in the presence of an acid or a base, or by reacting a compound of Formula V above wherein R<SP>5</SP> is H or C 1-3  alkyl, with a compound of the formula wherein X is halogen and R<SP>6</SP> is H or C 1-3  alkyl, in the presence of an alkali metal salt and, if desired, reducing the compound of Formula I above in which A is an unsubstituted or C 1-3  alkyl-substituted vinylene chain thus obtained with hydrogen, or compounds of Formula I above wherein R<SP>4</SP> is OH by hydrolysing the corresponding esters. Pharmaceutical compositions, having antiinflammatory and anti-pyretic activity and suitable for oral administration, comprise the above novel derivatives of o-anilinophenylaliphatic acid and pharmaceutically acceptable carriers. Reference has been directed by the Comptroller to Specification 1,205,759.
Patent GB-1258322-A (GB)
IPC: B65H9/14
Filed: 1969-04-29
Abstract: 1,258,322. Feeding sheets. MABEG MASCHINENBAU G.m.b.H. NACHF HENSE & PLEINES G.m.b.H. & CO. 29 April, 1969 [24 May, 1968], No. 21757/69. Heading B8R. Sheets (18, 19) are fed over a table 2 and registered against front stops 3, Figs. 1 and 2, and side stops 4 by means of sheets of air from nozzle means comprising a plurality of nozzles 14-17 connected to a source of air under pressure and individually or collectively rotatable angularly, e.g. by a hand wheel 13, to adjust the direction of the air flow, whereby the sheets are gently moved against and held against the stops 3 and the stops 4 at one side, until the stops 3 are moved to allow the sheets to be fed to a printing-machine.