baber/WOPTO huggingface dataset:
Patent DE-69333917-T2 (DE)
Inventor: DORIGATTI FRANCO
IPC: A61K6/898
Filed: 1993-04-16
Granted: 2006-08-10
Abstract: Bonding solutions for granular bone replacements are provided, comprising hyaluronic acid or hyaluronic acid derivatives such as hyaluronic acid esters and hyaluronic acid antibiotic salts in combination with natural or artificial bone granules. These solutions can be used in human and veterinary dentistry and bone surgery as granular bone replacements to promote the growth and repair of damaged or defective bone tissue.
Patent DE-69334022-T2 (DE)
Inventor: TANSEY CHARLES MARTIN
IPC: B65D49/12
Filed: 1993-07-14
Granted: 2006-12-07
Abstract: The invention provides a mould for use in the injection moulding of a closure (10) from a synthetic plastics material. Such a closure (10) is suitable for a container having an externally screw-threaded neck and comprising a top (15) and a depending skirt (16) which has on its internal surface a screw-thread complementary to the screw-thread on the container. A free edge of the depending skirt is joined by a plurality of frangible bridges (13) to a tamper-evident band (11) which comprises a generally cylindrical body portion and a continuous or segmented rib (18). The rib extends inwardly of the body portion and is adapted to provide a lip to engage under a retaining flange extending outwardly from the neck of the container below the screw-thread thereon. The rib (18) has an upper side facing generally towards the top of the closure and an under side facing generally away from the top. The mould defines the upper side of the rib (18) as comprising a first surface contiguous with the body portion of the band, which surface slopes inwardly and downwardly from the top portion (15), and a second surface which is positioned radially inwardly from the first surface, the second surface having a slope angle more nearly normal to the longitudinal axis of the closure than the first surface is to that longitudinal axis. The mould is capable of being operated at extremely high rates to produce closures with improved resistance to removal from the container. <IMAGE>
Patent DE-69402980-T2 (DE)
Inventor: ROUMAGNAC JEAN-PATRICK
IPC: A23L3/00
Filed: 1994-06-28
Granted: 1997-08-14
Abstract: PCT No. PCT/FR94/00778 Sec. 371 Date Dec. 28, 1995 Sec. 102(e) Date Dec. 28, 1995 PCT Filed Jun. 28, 1994 PCT Pub. No. WO95/01107 PCT Pub. Date Jan. 12, 1995The invention relates to a rotary drum structure for a sterilizer. The structure includes: four beams (30, 32, 34, 36) disposed parallel to said axis and defining a rectangular parallelepiped volume; a plurality of spacer elements (52, 54, 56) disposed in the four faces defining said parallelepiped volume and forming triangulated structures; a second end part (60) fixed to second ends of the beams to define an inlet opening (64) into said drum; and a circular running path (62).
Patent DE-69403808-T2 (DE)
Inventor: CRISTOFANI ALESSANDRO
IPC: B65D71/08
Filed: 1994-09-14
Granted: 1998-01-02
Abstract: Multiple packaging for bottles (1) consisting of a film (2) of heat-shrinkable plastic hot-applied to a plurality of bottles arranged alongside one another in parallel rows and comprising a series of incisions (3) in the regions of the planes separating adjacent rows of bottles. The packaging allows single rows of bottles to be detached, the latter being kept integral by the torn portion of packaging. A preferred method for manufacturing the packaging is described, based on a film of heat-shrinkable plastic provided with incisions.
Patent DE-69419248-T2 (DE)
Inventor: BARNES WAYNE M
IPC: C12Q1/686
Filed: 1994-02-22
Granted: 2000-01-27
Abstract: A DNA polymerase having an amino acid sequence comprising substantially the same amino acid sequence as that of Thermus aquaticus or Thermus flavus DNA polymerase, excluding the N-terminal 280 amino acid residues of Thermus aquaticus DNA polymerase or the N-terminal 279 amino acid residues of Thermus flavus DNA polymerase, recombinant DNA sequences encoding said DNA polymerases, vectors comprising said DNA sequences, and host cells containing such vectors. A formulation of thermostable DNA polymerases comprising a majority component comprised of at least one thermostable DNA polymerase of the type described above, wherein the DNA polymerase lacks 3'-exonuclease activity, and a minority component comprised of at least one thermostable DNA polymerase exhibiting 3'-exonuclease activity, and an improved method for amplifying nucleic acid sequences by polymerase chain reaction wherein the above formulation is mixed and used to catalyze primer extension, are also provided.
Patent DE-69430251-T2 (DE)
Inventor: GILBERT CARL W
IPC: C07K17/08
Filed: 1994-11-10
Granted: 2002-11-07
Abstract: A process is disclosed for preparing long-acting alpha interferon-containing compositions. Alpha interferon is contacted with a relatively small molar excess of a substantially non-antigenic polymer in the presence of a surfactant to preserve bioactivity. Isolation of the desired conjugate species having optimal activity is also disclosed.
Patent DE-69504182-T2 (DE)
Inventor: GROSS JOSEPH
IPC: A24F42/60
Filed: 1995-02-17
Granted: 1999-04-15
Abstract: PCT No. PCT/IE95/00019 Sec. 371 Date Dec. 23, 1996 Sec. 102(e) Date Dec. 23, 1996 PCT Filed Feb. 17, 1995 PCT Pub. No. WO95/24135 PCT Pub. Date Sep. 14, 1995A nicotine oral delivery device, which includes a hollow housing (10) and a hollow mouthpiece (14) which may be detachable connected to the housing (10) or may form with the housing a single piece. The mouthpiece includes a nicotine-containing material (16), in the form of a gel, on one or more of the outer surfaces of the mouthpiece. The housing (10) may also include flavoring (20), such as menthol. The nicotine-containing material (16) may be located as a layer on the mouthpiece (14), or in holes in the mouthpiece or under a permeable membrane (18) covering a portion of the mouthpiece (14). Where the mouthpiece and housing are separate pieces, the mouthpiece may be disposable while the housing reusable.
Patent DE-69507231-T2 (DE)
Inventor: VIEUX MICHEL
IPC: H01H11/00
Filed: 1995-07-12
Granted: 1999-09-02
Abstract: The switch mechanism is mounted in a box (20) and is operated by an on/off switch outside the mechanism. The on/off switch connects with protrusions on a bistable rocker circular section (25). The circular section has a hole for a connecting rod, which connects the circular section mechanically to an internal closing lever (24) hinged at one end. When the circular section rotates, the connecting rod closes the internal lever onto an electrical connector (23) closing the connection.
Patent DE-69520668-T2 (DE)
Inventor: SELSTED MICHAEL E
IPC: A61P31/04
Filed: 1995-02-10
Granted: 2001-09-06
Abstract: The present invention provides indolicidin analogs, which are tryptophan-rich peptides that have substantially the same amino acid sequence as naturally occurring indolicidin, exhibit broad spectrum antimicrobial activity and have antimicrobial selectivity as compared to naturally occurring indolicidin. The invention also provides methods of using an indolicidin analog to inhibit or prevent the survival or growth of a microorganism in an environment capable of sustaining such survival or growth. The invention provides, for example, methods of administering an effective amount of an indolicidin analog to an environment capable of sustaining the survival or growth of a microorganism.
Patent DE-69521985-T2 (DE)
Inventor: BURNIE PETER
IPC: C12R1/46
Filed: 1995-01-30
Granted: 2001-11-15
Abstract: The present invention provides a purified bacterial protein expressed during infection due to streptococci or enterococci and isolated from human sera, together with immunogenic fragments, analogs, inhibitors, antibodies and antigenic fragments specific thereto. Also provided is a DNA sequence coding for a bacterial protein or an immunogenic fragment or an analogue thereof expressed during infection due to Streptococci or Enterococci, together with homologues thereof, together with vectors, probes and inhibitors therefor. Also provided is fibronectin or an immunogenic fragment thereof or an analogue thereof or an antibody thereto or an anigen binding fragment thereof when used in a method of treatment or diagnosis of the human or animal body for infection due to Streptococci or Enterococci. Also provided are antibodies specific to HSP 90 or immunogenic fragments or analogues thereof for use in a method of diagnosis or treatment of the human or animal body of infection due to steptococci or enterococci due to any one of the group of S.oralis, S.gordonii, S.sanguis.
Patent DE-69526717-T2 (DE)
Inventor: JOHNSON PAUL A
IPC: F04B13/00
Filed: 1995-12-27
Granted: 2003-01-30
Abstract: A pump housing (11) is provided with a conduit (32) extending through the housing between a pump inlet (34) and pump outlet (36). A pump device (38) is disposed within the housing and in communication with the conduit to pump fluid therethrough. A fluid flow meter (42) also is disposed within the housing and in communication with the conduit (32) to monitor fluid flow rate through the conduit. The fluid flow meter generates signals related to the fluid flow rate which are fed back to a control device (50) operable to control the flow rate through the pump device. The flow meter may include a pair of meshed modified elliptical gears. The modified elliptical gears are based on a true elliptical shape, with bulged portions added between the major and minor axes of the elliptical shape. The modified elliptical gears have involute teeth that are relatively thick adjacent the minor axis and relatively thin adjacent the major axis.
Patent DE-69528263-T2 (DE)
Inventor: GROSZ RON
IPC: C12Q1/689
Filed: 1995-06-02
Granted: 2003-08-07
Abstract: A method is provided for the selection of diagnostic genetic markers fragments and useful in the identification of bacteria at the genus, species or serotype level. The method first involves the identification of a RAPD polymorphic DNA fragment common to a particular microbial group, the identification of the most conserved regions of that fragment, and the preparation of specific primers useful for detecting the presence of a marker within the fragment whereby that set of primers is then useful in the identification of all members of the chosen microbial group. Also provided is a specific diagnostic marker for Salmonella and primers directed thereto.
Patent DE-69532406-T2 (DE)
Inventor: PONROY YVES
IPC: A61K35/30
Filed: 1995-06-13
Granted: 2004-11-04
Abstract: PCT No. PCT/FR95/00771 Sec. 371 Date Feb. 27, 1996 Sec. 102(e) Date Feb. 27, 1996 PCT Filed Jun. 13, 1995 PCT Pub. No. WO96/00077 PCT Pub. Date Jan. 4, 1996The therapeutic or dietetic use of a preparation based on phospholipids extracted from pig brains for treating aging disorders consisting of memory disorders, attention disorders, intellectual efficacy disorders, humor and affectivity disorders, and thinking difficulty in a human is disclosed. The purified brain phospholipids are used alone or in combination with carriers and diluents enabling oral delivery.
Patent DE-69532690-T2 (DE)
Inventor: YAMANOBE MASATO
IPC: G09G3/22
Filed: 1995-09-22
Granted: 2005-01-13
Abstract: A method of manufacturing an electron emitting device (104) of the type having, on a substrate 1, an electroconductive thin film (3) with an electron-emitting region (2), connected to respective electrodes (4,5). The electroconductive film (3) is formed by spraying through a nozzle (33;131) a solution containing component elements of the electroconductive thin film (3) which is to be formed. Spraying is performed whilst an electrical potential difference (V) is produced between the electrodes (4,5), between the nozzle (131) and the substrate (1), or both. The effect is to improve adherence of the film (3) to the substrate (1) or substrate and electrodes (1,4,5). This method may be extended to the manufacture of an electron source (1,102-104) having an array of electron-emitting devices (104). <IMAGE>
Patent DE-69605404-T2 (DE)
Inventor: COOPE NICHOLAS
IPC: F41G3/32
Filed: 1996-02-21
Granted: 2000-07-06
Abstract: PCT No. PCT/GB96/00378 Sec. 371 Date Oct. 17, 1997 Sec. 102(e) Date Oct. 17, 1997 PCT Filed Feb. 21, 1996 PCT Pub. No. WO96/26410 PCT Pub. Date Aug. 29, 1996The displacement of a first object (6) relative to a second object (28) is measured by differential measurements from a photodetector (17) and an associated evaluation device (18). The photodetector (17) receives a measurement beam of radiation from a source (9) via a reflector (5) secured to object (6), and a reference beam of radiation from a source (10) via a reflector (26) secured to object (28). Sources (9, 10) are closely adjacent and in the focal plane of a collimating lens (13) through which both beams pass. Both beams are focused onto the detector (17) by a focusing lens (21). Because both beams pass through lenses (13, 21) movements thereof do not affect the displacement measurement. The remaining optical components which are used for beam steering and guidance are comparatively stable and so do not affect the displacement measurement
Patent DE-69610062-T2 (DE)
Inventor: CHANG SHANG-DE T
IPC: H01L27/115
Filed: 1996-11-19
Granted: 2001-05-03
Abstract: A P-channel single-poly non-volatile memory cell (10) having P+ source (20) and P+ drain regions (22) and a channel (30) extending therebetween is formed in an N-type well (12). An overlying poly-silicon floating gate (26) is separated from the N-well by a thin oxide layer (34). A P-type diffusion region (36) is formed in a portion of the N-well underlying the floating gate (26) and is thereby capacitively coupled to the floating gate (26). This P-type diffusion area serves as the control gate for the cell. Programming is accomplished by coupling a sufficient voltage to the floating gate (26) via the control gate (36) while biasing the source (20) and drain (22) regions so as to cause the tunneling of electrons from the P+ drain region (22) of the cell to the floating gate (26). In some embodiments, an additional P-type diffusion region underlying the floating gate and separated therefrom by a layer of tunnel oxide serve as an erase gate for the memory cell. In such embodiments, erasing of the cell is accomplished by causing electrons to tunnel from the floating gate to the erase gate. <IMAGE>
Patent DE-69610078-T2 (DE)
Inventor: HERNESNIEMI LASSE
IPC: D21D5/16
Filed: 1996-02-22
Granted: 2001-04-12
Abstract: A screen used in the production of cellulose pulp may be mounted in a digester to minimize traditional screen problems (including clogging) without introducing new problems. The screen comprises a screen plate having a plurality of slots formed in it with an inclination angle, which is 30-60° with respect to the bottom edge of the screen plate. The screen plate may comprise a plurality of parallel screen bars side-by-side, or an integral metal plate with slots formed in it. The slots have a width between 1-5 (e.g. 2-4) millimeters and a spacing between them of 3-9 millimeters.
Patent DE-69611239-T2 (DE)
Inventor: CHARRIN PHILIPPE
IPC: A01G5/04
Filed: 1996-05-23
Granted: 2001-08-09
Abstract: The holder consists of a cone made from a folded semi-circle of material, with a tab (3) and slits (4) to adjust its size, and opening vanes (11) at the top to make a hole through which the stems of a bouquet of flowers can be inserted. The holder can be held in shape with a ribbon threaded through holes (6) near its upper end, and a sheet (8) of wrapping paper can be used to cover the base and sides of the cone for presentation.  Variants of the design, either conical in cylindrical in shape, can be made with a base to hold a small amount of water which keeps the flowers fresh, e.g. as a temporary vase, or for transport.
Patent DE-69619052-T2 (DE)
Inventor: RONCHI CELESTINO
IPC: A61K9/10
Filed: 1996-10-21
Granted: 2002-11-14
Abstract: Anhydrous solid pharmaceutical composition for vaginal use, comprising at least one active ingredient in a mixture with conventional carriers and excipients, containing one or more muco-adhesive polymers dispersed in the carrier. These compositions allow for longer contact between the mucosa and the active ingredient and on-site residence, maintaining an effective therapeutic concentration for longer times.
Patent DE-69630776-T2 (DE)
Inventor: VENDRELY TIM
IPC: A61B17/15
Filed: 1996-02-15
Granted: 2004-09-23
Abstract: A cutting guide for resecting a patient's proximal tibia to receive a tibial prosthesis is disclosed. The cutting guide comprises an instrument body (76) and mounting means for attaching the cutting guide to a rod (21) that tracks the patient's intramedullary canal (12) which enables the surgeon to reference surgical cuts with respect to the patient's intramedullary canal. The cutting guide also comprises a cutting element (78) for being driven longitudinally into the proximal tibia during use, and at least one cutting guide surface (90, 91) for guiding a saw instrument of the surgeon.
Patent DE-69635163-T2 (DE)
Inventor: PALMER CHARLES
IPC: A61H31/00
Filed: 1996-11-21
Granted: 2006-06-14
Abstract: A chest brace apparatus prevents the chest wall from buckling inwards during spontaneous breathing efforts and provides negative distending intra-thoracic pressure to a patient. The apparatus includes a protective adhesive layer placed on the patients skin and a brace structure that is designed to attach to the adhesive layer. The adhesive layer has an inner surface and an outer surface, the inner surface adapted to adhere to a chest region of the patient and the outer surface manifesting an outer adherent layer for attachment to the brace structure. The brace structure is placed about the patient's chest region and includes a frontal segment with a patient-side adherent layer for joinder to the outer surface of the adhesive layer, and movement devices connected to the frontal resilient segment for imparting an outward flexure thereof so as to distend the patient's chest region by outward pressure exerted on the adhesive layer. A fluidically operated extension device can be connected to the frontal segment for control of distension thereof in response to a control action. The brace structure is further adapted to enable manual distension or compression of the thoracic contents.
Patent DE-69635843-T2 (DE)
Inventor: CHATTERJEE MALAYA
IPC: A61K31/70
Filed: 1996-12-19
Granted: 2006-10-05
Abstract: The present invention provides a monoclonal anti-Idiotype antibody 11D10 that elicits an immune response against a specific epitope of a high molecular weight mucin of human milk fat globule (HMFG) and a hybridoma that produces 11D10. The hybridoma that produces 11D10 was selected by specific procedures. 11D10 induces an immunological response to HMFG in mice, rabbits, monkeys and patients with advanced HMFG-associated tumors. This invention provides compositions derived from polynucleotide sequences encoding the variable light and/or variable heavy regions of monoclonal anti-idiotype antibody 11D10, as well as polypeptides encoded thereby. The invention also provides compositions which can be used in the detection or treatment of HMFG-associated tumors.
Patent DE-69704223-T2 (DE)
Inventor: MARTINELL GISPER-SAUCH ENRIQUE
IPC: B01L3/00
Filed: 1997-01-15
Granted: 2001-09-13
Abstract: The device comprises a moulded plate with a plurality of individual reaction compartments formed by an upper chamber and a lower chamber intended to contain the separating medium and reagents, characterised in that the upper reaction chamber receiving the liquids for the first phase of the reaction communicates with the lower cup carrying the separating medium by means of a narrow gap of which the width is controlled so that the meniscus formed by surface tension prevents the passage of the liquid contained freely to the cup, the liquid being able to pass thereto merely by the action of centrifugation. <IMAGE>
Patent DE-69704352-T2 (DE)
Inventor: BLAUKOVITSCH REINHARD
IPC: G11B7/26
Filed: 1997-08-28
Granted: 2001-07-12
Abstract: The invention relates to a method of obtaining a copy protected optical record carrier carrying information in different blocks, a method of accessing such a copy protected optical record carrier and such an optical record carrier itself. Access means for optical record carriers return different results when retrieving blocks, which contain incorrect address data in the corresponding subcode fields. A copy protection key will be implemented during manufacture of an optical record carrier by modifying the subcode address information of a predetermined pattern of blocks. It is normally not possible to copy incorrect address data onto an optical record carrier, since the address data will be newly generated during the copy process. Therefore, such a key can be utilized to distinguish between an original disc and a copied or non original disc. The key is preset before manufacturing of the optical record carrier itself and can therefore be used to encrypt the data stored on the optical record carrier. Upon accessing of the data, first the key is extracted from the optical record carrier and then the data can be decrypted utilizing this key. <IMAGE>
Patent DE-69705414-T2 (DE)
Inventor: VANDEVANTER R
IPC: A61K9/00
Filed: 1997-11-13
Granted: 2002-05-02
Abstract: An anti-Pseudomonas aeruginosa agent which is substantially pure biologically active colistin component, a mixture thereof or a pharmaceutically acceptable salt thereof delivered as an aerosol or dry powder formulation. A formulation and method for preparation of substantially pure biologically active colistin, its components, mixtures thereof and a pharmaceutically acceptable salts thereof. A method for treatment and prophylaxis of Pseudomonas aeruginosa, Stenotrophomonas maltophilia or other susceptible pulmonary bacterial infections.
Patent DE-69709647-T2 (DE)
Inventor: SHIOTA TATSUKI
IPC: C07D317/28
Filed: 1997-05-20
Granted: 2002-11-07
Abstract: Cyclic diamines of formula (I) or their pharmacologically acceptable acid addition salts, and their medical applications are described. These compounds inhibit the action of chemokines such as MIP-1a and/or MCP-1 on target cells, and are useful as a therapeutic drug and/or preventative drug in diseases, such as atherosclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissue.
Patent DE-69716073-T2 (DE)
Inventor: TUUNANEN VESA
IPC: H01B3/44
Filed: 1997-07-01
Granted: 2003-03-13
Abstract: PCT No. PCT/FI97/00428 Sec. 371 Date Feb. 23, 1999 Sec. 102(e) Date Feb. 23, 1999 PCT Filed Jul. 1, 1997 PCT Pub. No. WO98/01870 PCT Pub. Date Jan. 15, 1998The invention relates to a coaxial high-frequency cable including an inner conductor, a dielectric material formed about the inner conductor, and an outer conductor formed about the dielectric material. According to the invention, the dielectric material is made from an expanded polymer blend compounded from two a-olefin polymers of different densities, whereby the polymer of the higher density forms the matrix of the polymer blend.
Patent DE-69732249-T2 (DE)
Inventor: MORRIS B
IPC: A61M1/30
Filed: 1997-11-21
Granted: 2005-12-08
Abstract: An apparatus controls movement of fluids during an extracorporeal blood treatment session. A hollow cassette enclosure has a plurality of fluid input ports for receiving fluids into the enclosure and a plurality of fluid output ports for expelling fluids from the enclosure. Internal fluid passageways disposed within the hollow enclosure are provided for coupling together the fluid input ports, and the fluid output ports. At least one internal valve is disposed within the hollow enclosure for controlling movement of the fluid within the hollow enclosure. A filter is integrated into the cassette to filter the blood passing therethrough.