baber/WOPTO huggingface dataset:
Patent IL-174365-A0 (IL)
Title: Polyether brevetoxin derivatives as a treatment for cystic fibrosis, mucociliary dysfunction, and pulmonary diseases
IPC: C07D493/14
Filed: 2006-03-16
Abstract: Disclosed are compounds that are derivatives of brevetoxin, or PbTx, pharmaceutical formulations comprising the compounds, and methods of regulating mucus transport in a cell, treating mucociliary dysfunction and diseases related to decreased mucus transport, wherein the compounds are of the Formula (I), and Formula (III): wherein R, R1, R2, R3, A, n, and Y are as defined herein for each compound.
Patent IL-180445-A0 (IL)
Title: Stretch film
IPC: B29D28/00
Filed: 2006-12-28
Abstract: A stretch film comprising a base film made of a stretchable plastic film material, a multiplicity of holes in the base film arranged in several columns along a main direction, at least one reinforcement strip made of a stretchable plastic film material. The reinforcement strip is arranged and fixed on the base film in an area between two adjacent columns of holes. The thickness of the base film is greater than or equal to the thickness of the reinforcement strip and the width (w) of the reinforcement strip is as great as possible, but is such that the reinforcement strip does not contact or overlap the holes in the adjacent columns of holes. The reinforcement strip may be fixed to the base film so as to be inseparable and indistinguishable from the base film.
Patent IL-180984-A0 (IL)
Title: Pipe coupling
Filed: 2007-01-25
Abstract: A pipe coupling for joining together the ends of two adjacent pipes includes a housing for receiving the ends of the two adjacent pipes, and a locking arrangement which includes an annular chamber, and a plurality of grippers radially moveable towards the central axis of the housing from an inoperative condition to an operative condition. Each gripper includes a gripping formation for operatively gripping a pipe inserted into a bore of the housing, and a locking formation for operatively engaging a corresponding locking formation on the housing so as to axially lock the gripper to the housing. Each locking arrangement also includes a locking ring for locking the grippers to the housing so that axial displacement of the locking ring under fluid pressure within the annular chamber causes radial displacement of the grippers into the operative condition.
Patent IL-183377-A0 (IL)
Title: Stable pharmaceutical formulations of zonisamide and methods for their manufacture
Filed: 2007-05-24
Abstract: One of the embodiments of the present invention is directed toward a process for preparing a stable zonisamide pharmaceutical composition, comprising subjecting zonisamide to wet granulation with a granulation liquid to form a granulated mixture as the stable zonisamide pharmaceutical composition, wherein the granulation liquid is selected from purified water, alcohol and mixtures thereof. The stable zonisamide pharmaceutical composition can be used to fill capsule shells to prepare stable zonisamide capsules. Another embodiment of the invention concerns a for preparing a stable zonisamide pharmaceutical capsule, comprising  (i) forming an intimate mixture with zonisamide powder and an effective amount of at least one pharmaceutically acceptable excipient by compressing, co-milling, co-micronization and/or co-compaction of the components, or subjecting the components to a similarly intensive process; and  (ii) filling capsule shells with the intimate mixture to obtain the stable zonisamide pharmaceutical capsule.
Patent RO-132764-A0 (RO)
Title: Space airplanes and supersonic aircrafts with variable configuration for sonic boom reduction
Inventor: SANDU CONSTANTIN
IPC: B64D47/00
Filed: 2017-10-18
Abstract: The invention relates to space airplanes and supersonic aircrafts with variable configuration of fuselage, leading edge of wings and horizontal empennage, for reduction of sonic boom produced by the shock wave over populated areas. According to the invention, the space and supersonic airplanes have the nose's cone or the leading edge of wings or horizontal empennage consisting of a body (1) and an elastic fairing (2) made of a composite material based on carbon fibre, in the centre of the leading edge body or the nose's cone there being a compressed-air supply pipe (c) reaching some holes (g) located at certain distances along the leading edge, both on the lower side and on the upper side or around the front cone of the aircraft fuselage, and the fairing (2) being fragmented by some slots (f) for facilitating the flexion thereof, said fairing (2) being vibrated at its own frequency by a pulsatory compressed air system and reaching an amplitude of 1...2° which produces the shock wave scattering by an angle ΔΘ of few degrees.
Patent RO-135235-A0 (RO)
Title: Electrochemical biosensor for determining uric acid in biological fluids
Inventor: DICULESCU VICTOR CONSTANTIN
IPC: G01N33/48
Filed: 2021-03-25
Abstract: The invention relates to a process for making an electrochemical biosensor for detecting uric acid in biological fluids. According to the invention, the process consists of the following stages: manufacturing an electrode of electrospun polymer fibers of micro- and nano-metric sizes coated with palladium, immobilizing uricase on the electrode surface, measuring the current of reducing the superficial PdO layer formed at the surface of the electrode by reaction with H2O2, with uric acid detection limits lower than the usual methods of analysis.
Patent AP-2001002299-A0 (AP)
Title: Aryl or heteroaryl fused imidazole compounds as anti-inflammatory and analgesic agents.
Inventor: NAKAO KAZUNARI
IPC: A61P25/28
Filed: 2001-10-15
Abstract: This invention provides a compound of the formula (i); or the pharmaceutically acceptable salts thereof, wherein y1, y2, y3, and y4 are independently selected from n, ch, etc., r1 is h, c1-8 alkyl, etc., q1 is 5-12 membered monocyclic or bicyclic aromatic ring optonally containing up to 4 heteroatoms selected from o,n and s,etc., a is a 5-6 membered monocyclic aromatic ring optionally containing up to 3 heteroatoms selected from o,n and s,etc.;B is c1-6 alkylene optionally substituted with an oxo group, etc.; w is nh, o, etc.; r2 is h,c1-4 alkyl, etc.; z is a 5-12 membered monocyclic or bicyclic aromatic ring optionally containing up to 3 heteroatoms selected from o,n and s, etc.; l is halo, c1-4 alkyl,,etc.; m is0, 1 or 2; r3 and r4 are independently selected from o,n and s, etc.; l is halo, c1-4 alkyl ; r5 is h, c1-4 alkyl, etc.; q2 is a 5-12 membered monocyclic or bicyclic aromatic ring ortricyclic ring optionally containing up to 3 heteroatoms selected from o, n and s, etc. These compounds are useful for the treatment of medical conditions mediated by prostaglamndin such as pain, fever or inflammation, etc. This invention also provides a pharmaceutical composition comprising the above compound.
Patent AP-2002002554-A0 (AP)
Title: Ox (ADI) azolyl-hydroxamic acids useful as procollagen C- proteinase inhibitors.
Inventor: BAILEY SIMON
IPC: C07D413/06
Filed: 2000-12-12
Abstract: Compounds of formula (I) and their salts, solvates, prodrugs, etc., wherein the substituents have the values mentioned herein, are Procollagen C-Proteinase (PCP) inhibitors and have utility in conditions mediated by PCP.
Patent IE-880739-A1 (IE)
Title: The alignment of hip joint sockets in hip joint replacement
Inventor: FARMER MALCOLM HUGH
IPC: A61F2/32
Filed: 1988-09-14
Abstract: An apparatus for aligning an acetabular cup for proper placement in the socket 54 in hip joint replacement includes a frame having feet 61, 62 that are placed against and fastened to the anterior superior iliac spines 52 and the public tubercles 53 respectively of the pelvis.  A light beam is directed from a source 75 through an aperture 80 to a mirror 91 mounted on an implant inserted 2 by means of arm 92.  The light beam is reflected back from the mirror 91 to a target region 84 defined on faceplate 74.  When the incident and reflected beams are coincident, the cup is aligned for correct placement.  The faceplate 74 is rotatably (71) and pivotably (79) mounted for precise adjustment of the angles of abduction and anteversion respectively. <Figure 10>
Patent LU-87475-A1 (LU)
Inventor: TRUMPP GERHARD
IPC: H03K17/693
Filed: 1989-03-15
Abstract: In a broadband-signal switching device comprising a switching point matrix in FET technology, the matrix output lines Zi of which at least approximately reach one operating potential UDD, USS in each case before the actual switching-through phase ph in a precharging phase Pv and the outputs of which are in each case provided with an output amplifier circuit (Ai) which exhibits a chain circuit, inserted into the relevant output line, of a C-MOS inverter (J) and of a latch and a precharging clock-controlled switch S providing feedback for the C-MOS inverter, the series circuit of a further transistor Tw of the same channel type, the control electrode of which is connected to the inverter input, and of a further switch Sw precharging clock controlled in the opposite direction to the switch is connected in parallel with the transistor forming one inverter branch so that the inverter decision threshold is moved away from the precharging potential. <IMAGE>
Patent LU-92925-A1 (LU)
Title: Verfahren zum Untersuchen einer Probe mittels Lichtblatt-Mikroskopie und Lichtblatt-Mikroskop
Inventor: FAHRBACH FLORIAN
IPC: G02B27/00
Filed: 2015-12-23
Abstract: Die Erfindung betrifft ein Verfahren zum Untersuchen einer Probe mittels Lichtblatt- Mikroskopie, wobei eine in einer Beleuchtungsebene befindliche Probenfläche mittels eines sich in der Beleuchtungsebene ausbreitenden Lichtblattes beleuchtet und von der Beleuchtungsebene ausgehendes Detektionslicht detektiert wird. Das Verfahren zeichnet sich dadurch aus, dass eine Position eines Lichtblattfokus des Lichtblattes in der Beleuchtungsebene (26) durch Verändern der optischen Länge des Lichtweges des das Lichtblatt bildenden Beleuchtungslichtes bewegt wird.
Patent MA-18442-A1 (MA)
IPC: E04B1/00
Filed: 1979-05-21
Abstract: 1. A building unit comprising a rectangular floor platform (6) exclusively carried by a single foundation base (1) comprising for this purpose, in its upper part, four anchoring regions (3) disposed at the corners of a horizontal rectangle whose dimensions are distinctly less than those of said platform, and a roof platform (8) having the same shape and dimensions as the floor platform (6) and supported by a vertical tubular post disposed in vertical alignment with the base and rigid with the floor platform (6), characterised in that the rectangular floor platform (6) which carries the post (7) is exclusively supported by a rectangular and horizontal subjacent stiffening frame the two dimensions of which are less than those of the floor platform (6) and which is itself rigidly fixed to the foundation base (1) in such manner as to adjust its height relative to the four anchoring regions (3) which define a rectangle relative to which the frame (5) and the floor platform (6) are centred, said rectangle having in the longitudinal direction of the frame a dimension less than the length of the latter.
Patent MA-23332-A1 (MA)
Inventor: STUART B ROSENBLUM
IPC: C07D205/08
Filed: 1994-09-15
Abstract: Hydroxy-substd. azetidinone derivs. of formula (I) and their salts are new. Ar1,Ar2 = aryl (opt. substd. by 1-5 gps. R4); Ar3 = aryl (opt. substd. by 1-5 gps. R5); X, Y, Z = CH2, CH(1-6C alkyl) or C(di(1-6C alkyl); R, R2 = OR6, OCOR6, OCOOR9 or OCONR6R7; R1, R3 = H, 1-6C alkyl or aryl; q, r = 0 or 1; m, n, p = 0-4, provided that i) at least one of q and r is 1, and the sum of m, n q and r is 1-6, and ii) when p is 0 and r is 1, the sum of m, q and n is 1-5; R4 = 1-6C alkyl, OR6, OCOR6, OCOR9, O(CH2)sOR6, OCONR6R7, NR6R7, NR6COR7, NR6COOR9, NR9, NR6CONR7R8, NR6CONR7R8, NR6SO2R9, COOR6, CONR6R7, COR6, SO2NR6R7, S(O)tR9, O(CH2)uCOOR6, O(CH2)uCONR6R7, lower alkylCOOR6, CH=CH-COOR6, CF3, CN, NO2 or halogen; R5 = OR6, OCOR6, O(CO)R9, O(CH2)vOR6, -O(CO)NR6R7, NR6R7, NR6COR7, NR6COOR9, NR6COOR9, NR6CONR7R8, NR6SO2R9, COOR6, CONR6R7, COR6, SO2NR6R7, S(O)tR9, -O(CH2)uCOOR6, O(CH2)uCONR6R7, lower alkylCOOR6 or -CH=CH-COOR6; s = 1-5; t = 0-2; u = 1-10; v = 1-5; R6, R7, R8 = H, 1-6C alkyl (opt.substd. with aryl) or aryl; and R9 = 1-6C alkyl (opt. substd. with aryl) or aryl.
Patent MA-27370-A1 (MA)
Inventor: FRANCK CLAUSSE
IPC: C02F1/52
Filed: 2005-01-20
Abstract: A method of producing lime water comprising deionising dilution water by membrane filtration, distillation or an ion exchange resin and adding silicate ions to the deionised water. Thereafter, the deionised water treated with the silicate ions is mixed with milk of lime to form lime water. In one embodiment, the milk of lime and dilution water are mixed in a saturator where the silicate ions are introduced.
Patent MA-27729-A1 (MA)
Title: Compositions pharmaceutiques solides contenant un agoniste des recepteurs de la s1p et un alcool de sucre
Inventor: OOMURA TOMOYUKI
IPC: A61K31/137
Filed: 2005-10-19
Abstract: L'invention concerne une composition pharmaceutique solide pour administration orale, contenant : (a) un agoniste des récepteurs de la S1P et (b) un alcool de sucre.
Patent MA-40811-A1 (MA)
Title: Dispositif de couverture interchangeable pour serres
Inventor: BELMONTE MULA MANUELA
IPC: A01G9/22
Filed: 2015-09-15
Abstract: L'invention concerne un dispositif de couverture interchangeable pour serres formée de deux feuilles, l'une de plastique transparent (5) et l'autre constituée d'une structure maillée (6), la première étant reliée par l'un de ses bords à un profilé fixe et supérieur (4) et la seconde à l'axe (9) d'enroulement/déroulement de l'autre extrémité de la feuille de plastique, ce dispositif se caractérisant en ce que ledit axe (9), considéré comme primaire, est actionné par un moteur (8) coulissant sur des guides
Patent MA-55228-A1 (MA)
Title: Solution de prolongation de la conservation des fruits de fraises en post-récolte et son procédé d'application
Inventor: Errachidi Faouzi
IPC: A23B7/16
Filed: 2021-12-17
Abstract: La présente invention a pour objectif la prolongation de la conservation des fraises et fruits similaires en post-récolte. L’idée s’articule autour d’un traitement biologique par des produits naturels qui ne portent pas préjudice à l’environnement. L’invention fait intervenir du chitosane extrait, par l’acide citrique et les cendres de plantes calcinées, puis solubilisé dans l’acide acétique pour protéger les structures cellulaires des fruits de fraises contre les altérations microbiologiques et biochimiques. La prolongation de la conservation des fruits de fraises dure plusieurs jours, un temps justifié suffisant pour bien gérer la commercialisation de ces fruits très fragiles. Cette invention donnera une grande compétitivité sur le marché national et international.
Patent UY-24406-A1 (UY)
Title: Cabeza de cepillo de dientes contorneante
Inventor: HOHLBEIN DOUGLAS
IPC: A46B7/02
Filed: 1996-12-13
Abstract: Cepillo de dientes que tiene una cabeza articulada en dos secciones; dichas secciones se encuentran unidas entre sí en su parte inferior, por un puente del mismo material que el mango del cepillo, y en su parte superior, por una sección de elastómero que es deformada durante el cepillado. La sección de elastómero y el puente pueden estar dispuestos de varias maneras: sección con forma de T transversal longitudinal con dos ranuras paralelas sobre su parte superior, con el puente en su parte inferior; sección con forma de C transversal longitudinal, con el puente en su parte inferior; o sección con forma de T transversal longitudinal sin las ranuras paralelas sobre su parte superior, con el puente en su parte central. La figura 1 ilustra la presente invención.
Patent UY-25955-A1 (UY)
Title: Composiciones farmacéuticas con revestimiento entérico (ácido micofenólico)
Inventor: HAEBERLIN BARBARA
Filed: 2000-01-17
Abstract: Composición farmacéutica que incluye una sal micofenolicacuya composición esta adaptada para liberar el ácido minofenólico en la parte superior del tracto intestinal. en la parte superior del tracto intestinal. Composición farmacéutica que contiene una sal micofenólica, farmacéuticamente aceptable, con revestimiento entérico. Utilización de la sal en la preparación de un fármaco para inmunorepresión, especialmente para la prevención o tatamiento del rechazo de aloinjertos o xenoinjertos de órganos, tejidos o células para el tratamiento o la prevención de enfermedades con mediación inmunologica y/o enfermedades inflamatorias con administración simultanea o separadamente de un u otro inmunosupresor. Composición, utilización y método de acuerdo a cualquier valor anterior donde la sal sódica es la sal monosódica.
Patent UY-28049-A1 (UY)
Title: Derivados de (6,7-dihidro-5h-imidazo(1,2-a) imidazol-3-sulfonilamino)-propionamida
Inventor: KELLY TERENCE ALFRED
IPC: C07D487/04
Filed: 2003-10-28
Abstract: Derivados de (6,7-dihidro-5H-imidazo(1,2-a) imidazol-3-sulfonilamino)-propionamida que muestran buen efecto inhibidor sobre la interacción de CAM y leucointegrinas y son así útiles en el tratamiento de enfermedades inflamatorias.
Patent UY-28715-A1 (UY)
Title: Derivados de diarilmetil piperazina, sus preparaciones y sus usos
Inventor: BROWN WILLIAM
IPC: A61P25/04
Filed: 2005-01-07
Abstract: Compuestos de fórmula: en donde R1, R2, Y R3, son como se define en la memoria descriptiva, al igual que sales, anantiómeros del mismo y se preparan composiciones farmacéuticas que incluyen a los compuestos. Son útiles en terapia, en particular en el manejo del dolor.
Patent UY-28850-A1 (UY)
Title: Inhibidores de la dipeptidil peptidasa iv
Inventor: HULIN BERNARD
Filed: 2005-04-12
Abstract: La invención proporciona compuestos de fórmula (I): o profármacos de los mismos o sales farmacéuticamente aceptables de dichos compuestos o profármacos o solvatos de dichos compuestos, profármacos o sales, en los que A, N, X y R1 son como se definió en la presente memoria, composiciones farmacéuticas de los mismos; útiles para el tratamiento de la diabetes y enfermedades que están asociadas con proteínas que están sometidas a un procedimiento por DPP-IV.
Patent UY-30154-A1 (UY)
Title: Uso de derivados de benzo-heteroaril sulfamidas en eltratamiento de modificacion de enfermedad/epileptogenesis
Inventor: SMITH-SWINTOSKY VIRGINIA L
IPC: C07D307/81
Filed: 2007-02-14
Abstract: La presente invención es un método para tratar, prevenir, revertir, detener o inhibir la aparición, desarrollo y maduración de ataques o tratornos relacionados con ataques. Más específicamente, la presente invención se refiere a métodos para el uso de derivados de benzo-heteroaril sulfamidas de Fórmula (I) como se describe en la presente para tratar, prevenir, revertir, detener o inhibir terapéutica o profilácticamente la epileptogénesis y la epilepsia.
Patent UY-30523-A1 (UY)
Title: Derivados de pirazol[4,3-d]tiazol, su preparacion y su aplicacion en terapéutica.
Inventor: DOERFLINGER GILLES
IPC: A61P35/00
Filed: 2007-08-03
Abstract: Se divulga un compuesto de formula (I), derivados de pirazol[4,3-d]tiazol, las composiciones que los contienen y su aplicacion en terapéutica, principalmente como anticancerígenos. La invencion se refiere también al procedimiento de preparacion de estos compuestos así como a algunos de los productos intermadios. Los compuestos de la invencion están destinados a la prevencion o al tratamiento de enfermedades en las que están implicadas enzimas metabolicas elegidas entre las quinasas y al tratamiento y a la prevencion del cáncer.
Patent ZW-12388-A1 (ZW)
Title: Immunomodulatory azaspiranes
Inventor: ALISON MARY BADGER
IPC: C07D215/00
Filed: 1988-09-21
Abstract: The invention relates to pharmaceutical compositions containing immunomodulatory azaspiranes of the formulae (I) and (II): <CHEM> wherein n is 3-7, m is 1 or 2, and R<1> to R<6> are hydrogen or alkyl. Also disclosed are novel azaspiranes and processes for their preparation.
Patent ES-188117-A1 (ES)
Title: PROCEDIMIENTO DE FABRICACIoN DE UNA PASTA PARA SOLDAR METALES EN FRiO
Filed: 1949-05-07
Abstract: Procedimiento de fabricación de una pasta para soldar metales en frío caracterizado porque se procede primeramente a la limpieza de recortes de films al objeto de quitarles la capa de gelatina que contiene lo que se efectúa en recipientes con agua calentados al fuego provistos de un agitador eléctrico y posteriormente pasan a los recortes a una agitadora con agua corriente donde terminen de limpiarse y una vez limpios pasan a un secadero de aire caliente filtrado y después a una cortadora eléctrica que desmenuza los recortes.
Patent ES-194666-A1 (ES)
Title: Un aparato registrador para sondeo de profundidad
IPC: G01S1/72
Filed: 1950-09-22
Abstract: Un aparato registrador en el cual un medio de registro se desplaza sobre una platina y es marcado por un dispositivo marcador que incluye un instrumento llevado a través de dicho medio, y el dispositivo marcador comprende un estilete montado sobre un soporte unido a una correa sin fin guiada sobre ruedas de polea que están montadas en los lados opuestos del medio de registro, caracterizado porque se dispone un borde recto o regla muy junto a dicho medio de registro y el estilete es puesto en tensión contra dicho borde recto o regla, para hacer de este modo que dicho estilete siga una línea recta a través de dicho medio.
Patent ES-194771-A1 (ES)
Title: UN DISPOSITIVO DE SUSPENSIoN POETERIOR PARA MOTOPATINETE CONSTITUIDO POR UN uNICO BRAZO DE SECCIoN CIRCULAR
Filed: 1950-09-29
Abstract: Un dispositivo de suspensión posterior para motopatinete según se describe caracterizado por el hecho de estar constituído por un único brazo de sección circular curvo soldado al tronco del tubo que aloja las arandelas y el perno de anclaje de la suspensión en los dos montantes del bastidor del motopatinete.
Patent ES-196559-A1 (ES)
Title: PROCEDIMIENTO PARA OBTENCIoN DE áCIDOS GRASOS NO SATURADOS DE W-FURIL-(2)
Filed: 1951-02-14
Abstract: Procedimiento para la obtención de ácidos w-furil-(2) no saturados por oxidación de w-furil-(2)-cetonas no saturadas caracterizado porque las w-furil-(2)-cetonas no saturadas simultáneamente con una disolución de hipoclorito se introducen en un medio alcalino calentado previamente dado el caso a la temepratura de reacción.
Patent ES-197203-A1 (ES)
Title: Un procedimiento de fabricacion de un antifermento para evitar el ahilamiento de las masas panificables
Filed: 1951-03-31
Abstract: Procedimiento de fabricación de un antifermento para evitar el ahilamiento de las masas panificables caracterizado porque después de un escrupuloso pesado y dosificación se mezclaran Ácido acético Ácido tartario Ácido láctico Ácido clorhidrico y agua destilada después de lo cual se removerán convenientemente para su perfecta homogeneización.
Patent ES-321703-A1 (ES)
Title: Improvements in or relating to tyre casings
IPC: B60C9/02
Filed: 1966-01-13
Abstract: A pneumatic tyre comprises a radial cord carcass ply 10 of which the edges 11 terminate in the region of greatest axial width of the tyre and are separated from the central part of the ply by a rubber layer 17, of a thickness between one and a half to five times that of the ply 10, so as to obviate separation of the ends 11. The layer 17 is preferably of sidewall rubber and the cord ends are encased in hard gum staple 18. The beads are stiffened by a filler 19, bias-laid cord strips 20 and a hard gum strip 2].