baber/WOPTO huggingface dataset:
Patent DE-69201753-T2 (DE)
Inventor: JUGIAN JEAN-JACQUES
IPC: B65D33/16
Filed: 1992-05-26
Granted: 1995-07-27
Abstract: Closing and opening device for a thin-film packaging packet or bag in which the free edges of the envelope forming the packet or bag are brought together in order to form a bag head, and are then folded down or folded over. The non-heat-welded fold or folds (p) of the head of the packet or bag (S) are held by a label (20) affixed to the packet or bag (S') so as to straddle the said fold or folds (p), the face of the label (20) in contact with the bag (S') being equipped with a permanent adhesive which is absent or is masked in a zone where a pre-cut-out tab (32), intended to separate the label into two distinct portions, is provided, the said tab being integral with the rest of the label as long as the packet or bag (S') has not been opened for the first time. <IMAGE>
Patent DE-69209094-T2 (DE)
Inventor: AUDIAU FRANCOIS
IPC: C07D277/82
Filed: 1992-12-09
Granted: 1996-09-19
Abstract: PCT No. PCT/FR92/01165 Sec. 371 Date Jun. 13, 1994 Sec. 102(e) Date Jun. 13, 1994 PCT Filed Dec. 9, 1992 PCT Pub. No. WO93/12099 PCT Pub. Date Jun. 24, 1993This invention relates to the process for the preparation of 2-amino 7-nitro benzothiazoles of formula (I)    <IMAGE>  (I)  consisting in a) nitrating a derivative of formula (II)    <IMAGE>  (II)  and b) reacting the compound of formula (III) a.
Patent DE-69211705-T2 (DE)
Inventor: DORTA ANTONIO
IPC: C13B20/14
Filed: 1992-09-28
Granted: 1997-02-20
Abstract: The present invention is a process for the chromatographic separation of a liquid mixture comprising a first sugar component and at least one secondary component chosen from second sugars, organic acids and salts thereof, alcohols, amino acids, and inorganic salts. In the process, the liquid mixture is contacted with a stratum of a porous gel cation-exchange resin and thereafter eluted such that the first sugar component passes through the stratum at a different rate relative to the secondary components of the liquid mixture. The separation results in a first recoverable product stream rich in the first sugar component and at least one secondary product stream rich in the secondary components. The porous gel cation-exchange resin is prepared by polymerization of at least one monovinylidene monomer with a cross-linking monomer in the presence of an inert diluent. The use of such porous gel resins in the process increases kinetics, improves yields of desired sugar components, and results in a more efficient separation process. The invention is particularly applicable to separation of glucose from fructose in the preparation of high fructose corn syrup.
Patent DE-69213738-T2 (DE)
Inventor: GOLDSTEIN STEVEN
IPC: A61K31/425
Filed: 1992-05-04
Granted: 1997-01-30
Abstract: Compounds of formula (I) where R is alkyl, cycloalkyl, phenyl or substituted phenyl are useful as hypoglycemic agents.
Patent DE-69213812-T2 (DE)
Inventor: AID JAMES D
IPC: F04B7/06
Filed: 1992-04-08
Granted: 1997-04-30
Abstract: A valveless positive displacement pump (60) including a closed end cylinder (84) having two fluid inlet and outlet ports (90,92) adjacent an end (134) which is closed by a resilient end cap (88,88',88'',174,178) to relieve positive and negative pressures caused by piston movement when the inlet and outlet ports are closed. The end cap does this without introducing significant error in pumping accuracy. The end cap includes a resilient diaphragm (132,132',132'',176,182) which is formed either integrally or separately from the rest of the end cap.
Patent DE-69216210-T2 (DE)
Inventor: GHOSH TIRTHANKAR
IPC: A01N43/80
Filed: 1992-11-04
Granted: 1997-04-17
Abstract: A method of stabilizing a 3-isothiazolone compound against chemical decomposition, comprising introducing a sufficient amount of an alkene to stabilize said 3-isothiazolone compound is disclosed.
Patent DE-69219094-T2 (DE)
Inventor: VLADESCU BARBU-DINU VLADIMIR
IPC: C12G3/02
Filed: 1992-12-17
Granted: 1997-10-02
Abstract: The subject of the present invention is a process for the production of anthranilic acid and methyl anthranilate using Saccharomyces cerevisiae mutants and the use of these mutants in the production of fermented beverages. According to the invention, a mutant of a Saccharomyces cerevisiae yeast strain which is auxotrophic for tryptophan, blocked at the step catalysed by 5-P-ribosylanthanilate transferase and having an anthranilate synthase which is insensitive to feedback inhibition by tryptophan, is used.
Patent DE-69220879-T2 (DE)
Inventor: BAUDY REINHARDT BERNHARD
IPC: A61K31/675
Filed: 1992-10-08
Granted: 1997-11-20
Abstract: The compounds of the formula <CHEM>  wherein     R is hydrogen, lower alkyl, benzyl or pivaloyloxymethyl; R<1> and R<2> are, independently, hydrogen, lower alkyl, lower alkoxy, trifluoromethyl, trifluoromethoxy, methanesulfonylamino, acetylamino, or halo, or when taken together R<1> and R<2> represent a methylenedioxy grouping; and the pharmacologically acceptable salts thereof are NMDA antagonists useful in the treatment and prevention of central nervous system related pathological conditions resulting from overstimulation by excitatory amino acids. Processes for preparing the compounds and pharmaceutical compositions containing them are also covered.
Patent DE-69221162-T2 (DE)
Inventor: WALKER PETER STANLEY
IPC: A61F2/38
Filed: 1992-01-31
Granted: 1997-11-27
Abstract: A knee prosthesis includes a femoral component in which the condyles have a continuous contact surface for the tibial bearing surface and in which the sagittal radius is constant from posterior to a point more anterior than the distalmost point. The tibial bearing surface is shaped to have a curvature which corresponds closely with that of the femoral condylar surfaces. The tibial component includes a plastics meniscus component supported on a metal platform for sliding movement in the anterior-posterior direction and the mating surface between the meniscus and platform has a sagittal curvature which is larger than the sagittal radius of the femoral condyles.
Patent DE-69303690-T2 (DE)
Inventor: OBER FRANK
IPC: B26D1/20
Filed: 1993-10-28
Granted: 1997-01-02
Abstract: A cutter assembly for cutting sheets of relatively thin material is disclosed. The cutter assembly comprises a base member (18), a pair of support posts (14,16) securely attached to the base member (18), and an elongated guide rail (12) having a first end (12a) and a second end (12b) supported by the support posts (14,16) in laterally spaced relation to the base member (18). A cutting strip (22) is securely retained by the base member (18) for receiving the sheets of material thereon. There is a cutter head (20) slidably mounted on the elongated guide rail (12), and a cutting wheel (64) operatively retained in rotatable relation by the cutter head (20). A spring biasing means (90) biases the cutting wheel (64) toward the cutting strip (22) such that the cutting wheel (64) is received in intimately contracting relation against the cutting strip (22). The cutting wheel (64) moves along the elongated guide rail (12) so as to intimately contact the cutting strip (22) along the length thereof, so as to thereby permit cutting of the sheets of material when they are between the cutting wheel (64) and the cutting strip (22). A spring member (102) is disposed between upper (40) and lower (38) members of the base member (18) so as to camber the upper member (40) to match the bowing of the elongated guide rail (12) that occurs as the cutting wheel (64) moves along the elongated guide rail (12) and therefore along cutting strip (22) to cut the sheets of material. <IMAGE>   <IMAGE>
Patent DE-69307702-T2 (DE)
Inventor: MCDONALD IAN
IPC: A61K31/135
Filed: 1993-04-14
Granted: 1997-05-28
Abstract: The present invention relates to a method of treatment for Alzheimer's disease in a patient in need thereof comprising administering to said patient a therapeutically effective amount of (E)-2-(p-fluorophenethyl)-3-fluoroallylamine or a pharmaceutically acceptable salt thereof.
Patent DE-69309746-T2 (DE)
Inventor: STONEY ARTHUR
IPC: F24F13/18
Filed: 1993-02-19
Granted: 1997-07-31
Abstract: A controllable slot ventilator comprises first and second parallel side walls (28,30) which define an air passage (32) between them. A closure member (34) is mounted adjacent the front edges of the side walls via parallel motion links, which allow the closure member to move generally away from and towards the side walls to open and close the ventilator. At the rear of the side walls, i.e. the opposite end to the closure member, a mounting flange (38) is fitted, whereby the ventilator is mounted to a member. When the ventilator is installed in a slot, it is preassembled and then inserted into the slot from one end. <IMAGE>
Patent DE-69309937-T2 (DE)
Inventor: LEPPAENEN JYRKI
IPC: C25B1/12
Filed: 1993-08-31
Granted: 1997-10-16
Abstract: PCT No. PCT/FI93/00343 Sec. 371 Date Apr. 20, 1995 Sec. 102(e) Date Apr. 20, 1995 PCT Filed Aug. 31, 1993 PCT Pub. No. WO94/05830 PCT Pub. Date Mar. 17, 1994In an electrolysis apparatus according to the invention for producing hydrogen by decomposing electrolysis liquid with the aid of electric current into hydrogen and oxygen in a pressurized electrolytic cell (11), an electrolytic cell (11) is placed within a liquid-filled pressure shell (10) maintained pressurized with the pressure of a gas produced in electrolysis. The liquid can be selected, for instance, among the following group: silicon oils or fats, fluorized oils, crude oil-based or synthetic oils, or water.
Patent DE-69315396-T2 (DE)
Inventor: ALEDO EDUARDO CESAR ANDREO
IPC: A61F13/15
Filed: 1993-09-01
Granted: 1998-06-18
Abstract: The invention refers to a disposable diaper aimed at avoiding or reducing leakage characterized by comprising regions of elevation and depression of opposite concavities in such a way that when the said diaper is put to use, the user's perineum is located between the two such regions, being the elevation region anterior and constrained at the encounter of the user's body, and being the depression region posterior and constrained in direction contrary to the user's body.
Patent DE-69316145-T2 (DE)
Inventor: ERMACORA RINO
IPC: A01D43/10
Filed: 1993-10-12
Granted: 1998-09-03
Abstract: The invention relates to a mower comprising two conditioning (treatment) rollers (66, 67), drive members (90) serving to drive one of the two conditioning rollers and transmission members (91) transmitting the rotational movement from one of the conditioning rollers to the other. According to the invention, the mower is characterised by the fact that:     - the transmission members (91) are embedded in a casing (97); - this casing (97) includes a first part (98) and a second part (99) which are joined together by means of an articulation (hinge) (100) of geometric axis (101) pointing at least substantially parallel to the axes of rotation (67A, 66A) of the conditioning rollers (67, 66); and - each of the said parts (98, 99) is furthermore mounted pivotably at least substantially about the axis of rotation (67A, 66A) of the corresponding conditioning roller (67, 66).   <IMAGE>
Patent DE-69319761-T2 (DE)
Inventor: BARDO CHARLES J
IPC: F28C1/00
Filed: 1993-02-24
Granted: 1998-12-03
Abstract: The present invention provides a structural assembly (10) that includes at least four vertically extending columns (30) which form corners of the structural assembly. Wall panels (32,34,36) extend between adjacent columns, with at least two wall panels vertically stacked and connected to each other, to form a structural wall assembly between adjacent columns. The ends of each of the wall panels are attached to flanges that extend from each of the columns. A structural column (24) is provided in the center of the structure and braces (74,75) extend from each of the corner columns to the riser. Beams (58,90) also extend from the central riser outwardly to certain of the wall panels, usually connecting to the wall panels at a location equidistant between the columns. A roof structure (112) is provided, the edges of which are received in spaces in certain of the top wall panels. In a cooling tower application of the present invention, a fan assembly (12) is supported on the top of the central column water inlet riser (24) and includes a fan shroud supported by the roof. <IMAGE>
Patent DE-69324367-T2 (DE)
Inventor: GEBEYEHU GULILAT
IPC: C12N5/10
Filed: 1993-08-27
Granted: 1999-09-23
Abstract: The present invention discloses cationic lipids useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-dependent transformation of cells. Also disclosed are lipids useful both for the delivery of macromolecules and also useful as intermediates for making other such lipids.
Patent DE-69325450-T2 (DE)
Inventor: OELUND KARIN
IPC: A61K31/23
Filed: 1993-03-31
Granted: 1999-12-23
Abstract: PCT No. PCT/SE93/00275 Sec. 371 Date Sep. 27, 1994 Sec. 102(e) Date Sep. 27, 1994 PCT Filed Mar. 31, 1993 PCT Pub. No. WO93/20812 PCT Pub. Date Oct. 28, 1993An antimicrobial composition comprising an antimicrobially effective amount of a combination of: A) a monoglyceride of lauric acid, a monoglyceride of monomyristic acid or a mixture of these monoglycerides, and B) at least one chemical substance selected from the following groups: i) local anesthetics of the amide type; ii) carbamide, iii) antibacterial substances in the form of steroid antibiotics, imidazole derivatives or nitroimidazole derivatives, and iv) diols with 3-6 carbon atoms, and C) optionally, a conventional physiologically acceptable carrier and/or physiologically acceptable additives. A process for the preparation of this composition by heating (A) to the transition temperature of the lipid, adding (B), and optionally (C), and cooling the mixture to form a solid lipid crystal composition. Use of the composition for the preparation of a dermatological preparation for combatting bacteria and fungi or as a preservative additive in a cosmetic product, a food product, or a medical product.
Patent DE-69326691-T2 (DE)
Inventor: MUSSCHOOT ALBERT
IPC: B22D29/02
Filed: 1993-12-08
Granted: 2000-03-02
Abstract: A vibratory material handling apparatus (10) is provided for mixing of materials, cleaning, blending and/or shake out of castings or the like. The apparatus comprises a container (12) having a material supporting surface (14) disposed along a generally horizontal longitudinal axis (16). The container has a material input end and a material discharge end axially spaced therefrom and it is resiliently mounted relative to a mounting surface. The apparatus also includes a vibration generator (34) for producing a force to cause material within the container to be directed in a path of tumbling movement generally in a direction from the material input end toward the material discharge end of the container. With this arrangement, a tumbling assist mechanism (40) is provided for applying a force to the material in addition to the force produced by the vibration generator (34) to facilitate tumbling of the material as it moves along the path of tumbling movement. <IMAGE>
Patent DE-69327240-T2 (DE)
Inventor: EBETINO FRANK
IPC: A61P43/00
Filed: 1993-05-27
Granted: 2000-07-20
Abstract: The present invention relates to a quaternary nitrogen-containing, saturated or unsaturated monocyclic and bicyclic ring containing phosphonate and the pharmaceutically-acceptable salts and esters thereof, having structure (I). The present invention further relates to pharmaceutical compositions containing a safe and effective amount of a compound of the present invention, and pharmaceutically-acceptable excipients. Finally, the present invention relates to methods for treating or preventing pathological conditions characterized by abnormal calcium and phosphate metabolism in humans or other mammals. This method comprises administering to a human or other mammal in need of such treatment of a safe and effective amount of a compound or composition of the present invention.
Patent DE-69330498-T2 (DE)
Inventor: EBETINO FRANK HALLOCK
IPC: A61K31/66
Filed: 1993-05-27
Granted: 2002-05-23
Abstract: The present invention relates to phosphonsulfonates and the pharmaceutically-acceptable salts and esters thereof, having the following structure according to formula (I):    <IMAGE>  (I)  The present invention further relates to pharmaceutical compositions containing a safe and effective amount of a compound of the present invention, and pharmaceutically-acceptable excipients. Finally, the present invention relates to methods for treating or preventing pathological conditions characterized by abnormal calcium and phosphate metabolism in humans or other mammals, including treating or preventing osteoporosis and arthritis, especially rheumatoid arthritis and osteoarthritis. This method comprises administering to a human or other mammal in need of such treatment of a safe and effective amount of a compound or composition of the present invention.
Patent DE-69333243-T2 (DE)
Inventor: BAUER S CHRISTOPHER
IPC: C07K17/00
Filed: 1993-11-22
Granted: 2004-08-19
Abstract: The present invention relates to recombinant human interleukin-3 (hIL-3) variant or mutant proteins (muteins). These hIL-3 muteins contain one or more amino acid substitutions and may also have amino acid deletions at both the N- and C- termini. The invention also relates to pharmaceutical compositions containing the hIL-3 muteins and methods for using them. Additionally, the present invention relates to recombinant expression vectors comprising nucleotide sequences encoding the hIL-3 muteins, related microbial expression systems, and processes for making the hIL-3 muteins using the microbial expression systems. <??>Included in the present invention are deletion mutants of hIL-3 in which from 1 to 14 amino acids have been deleted from the N-terminus, and from 1 to 15 amino acids (corresponding to residues 119 to 133) have been deleted from the C-terminus, and which also contain one to three amino acid substitutions in the polypeptide. These hIL-3 mutant polypeptides may have biological activities similar to or better than hIL-3 and, in some cases, may also have an improved side effect profile.
Patent DE-69401366-T2 (DE)
Inventor: SHIMURA KENICHI
IPC: A61L27/34
Filed: 1994-02-08
Granted: 1997-05-28
Abstract: This invention provides a medical tool the surface of which is enabled to acquire lasting lubricity (low friction) by assuming a state wetted with bodily fluid or aqueous solution. This surface is formed without requiring the coating work to be repeated. The medical tool is produced by coating a water-swellable polymer having in the molecular unit thereof a reactive functional group capable of being reacted with a proton-donating group, on the surface of a matrix material possessing the proton-donating group, and also by coating a water-swellable polymer having in the molecular unit thereof a reactive group capable of being reacted with an acid anhydride group on the surface of a matrix material possessing the acid anhydride group.
Patent DE-69402575-T2 (DE)
Inventor: RANGEL FABIO EDUARDO FRANCA
IPC: A46B3/22
Filed: 1994-02-02
Granted: 1997-09-18
Abstract: This is an invention of a dental brush characterized by comprising a dispersed thermochromic material in its head and/or bristles, in such a manner that a change in coloration of these elements occurs in a time which the user associates to the minimum adequate time for a good brushing.
Patent DE-69409401-T2 (DE)
Inventor: STEWART SANDY
IPC: G01N33/531
Filed: 1994-11-29
Granted: 1998-10-01
Abstract: The present invention is drawn to an immunoassay capable of the rapid detection of a variety of test substances that may be present in a test sample. One feature of the invention is that extraction or isolation of the test substance occurs simultaneously with the formation of the primary antigen-test substance complex. The primary antigen-test substance complex is then captured in a solid phase format having a plurality of interstitial spaces which facilitate rapid and efficient detection. The immunoassay of the present invention works over a wide range of environmental conditions and is simple enough to be used in the absence of laboratory facilities.
Patent DE-69417042-T2 (DE)
Inventor: ADAMS HAROLD
IPC: E04F15/024
Filed: 1994-08-17
Granted: 1999-09-23
Abstract: A raised flooring system and methods of forming components of such a system are disclosed. Systems consistent with embodiments of the present invention utilize thin sheet metal, typically galvanized steel, base plates laid side by side on an existing floor. Attached in a rectilinear pattern to the base plates are stand-offs, which support floor panels forming the raised or false floor (which in turn are typically covered with carpet tile). In addition to supporting the floor panels, the stand-offs form a network of channels where conduit, cables, hoses, pipe and similar materials can be routed. The stand-offs are punched and then formed from thin sheet metal, also typically galvanized steel, and have an overall shape generally that of a truncated cone achieved with four arms that have rolled edges for enhanced load-bearing capacity.
Patent DE-69422553-T2 (DE)
Inventor: ROONEY JOHN M
IPC: C09D11/10
Filed: 1994-05-30
Granted: 2000-06-21
Abstract: A thermosetting printing ink compsn. comprises: (a) a copolymer of a thermosettable polyester and a polysiloxane comprising a hydrogen-terminated polyalkylene oxide-modified polymethylsiloxane of number average mol.wt. 3,000-5,000 an formula (I); (CH3)3SiO[(CH3)2SiO]x[CH3-Si(PE)O]ySi(CH3)3 (I) PE = -CH2CH2CH2O(EO)m(PO)n(BO)qH; EO = ethylenoxy; PO= propyleneoxy; BO= butyleneoxy; m, n, q = 0-10, provided that m+n+q = 1 or more; x = 0-250; and y = 1-500; the copolymer contains 1.9-5 wt.% polysiloxane; (b) a pigment; (c) a crosslinking agent; and (d) a curing catalyst comprising a strong acid or its metal salt.
Patent DE-69425197-T2 (DE)
Inventor: NISHIKAWA KATSUMI
IPC: G01N33/86
Filed: 1994-08-05
Granted: 2001-03-15
Abstract: The present invention offers a method of measuring the activity of tested substances utilizing the reconstituted plasma kallikrein-kinin system. A series of enzymatic reactions is started wherein an activation of a blood coagulation factor XII is an initiating reachtion in the presence of the tested substance in a reconstituted plasma kallikrein-kinin system, then the reaction is stopped and the physiologically active substance produced in said reaction is quantitatively determined. In the measuring method of the activity according to the present invention, the real activity (a promoting or inhibiting ability) of the tested substance against the production of the produced physiologically active substance can be easily, simply, quickly and precisely measured by a reaction system wherein the contaminating other factors are substantially removed. Accordingly, the method of measuring the activity in accordance with the present invention can be a very advantageous means for determining the action which is useful for adjusting the bioregulations in, for example, the plasma kallikrein-kinin system, the blood clotting system, the fibrinolusis system, etc. and also for developing such drugs.
Patent DE-69428290-T2 (DE)
Inventor: RAO A GURURAJ
IPC: C12N15/29
Filed: 1994-01-12
Granted: 2002-04-18
Abstract: Derivatives of alpha-hordothionin made by position-specific substitution with lysine residues provide lysine enrichment while retaining the antifungal activity of the parent compound.