baber/WOPTO huggingface dataset:
Patent CA-2653028-C (CA)
Title: Method for the enzymatic production of 2-hydroxy-2-methyl carboxylic acids
Inventor: MUELLER ROLAND H
IPC: C12P7/52
Filed: 2007-03-23
Granted: 2015-05-26
Abstract: The present invention relates to a method for the enzymatic production of 2-hydroxy-2-methyl carboxylic acids from 3-hydroxy carboxylic acids, where a 3-hydroxy carboxylic acid is produced in an aqueous reaction solution and/or is added to this reaction solution and is incubated. The aqueous reaction solution comprises a unit having 3-hydroxy-carboxylate-CoA mutase activity which has both 3-hydroxy-carbonyl-CoA ester-producing and 3-hydroxy-carbonyl-CoA ester-isomerizing activity and converts the 3-hydroxy carboxylic acid into the corresponding 2-hydroxy-2-methyl carboxylic acid which is isolated as acid or in the form of its salts. In a preferred embodiment, the unit having 3-hydroxy-carboxylate-CoA mutase activity is a unit which includes an isolated cobalamin-dependent mutase and where appropriate a 3-hydroxy-carbonyl-CoA ester-producing enzyme or enzyme system or a microorganism including them. The invention preferably relates to a biotechnological process for producing 2-hydroxy-2-methyl carboxylic acids, where microorganisms which have the desired activities are cultured in an aqueous system with the aid of simple natural products and convert intracellularly formed 3-hydroxy-carbonyl-CoA esters into the corresponding 2-hydroxy-2-methyl carboxylic acids. The invention likewise encompasses the production of unsaturated 2-methyl carboxylic acids, where the 2-hydroxy-2-methyl carboxylic acids obtained are converted by dehydration into the corresponding unsaturated 2-methyl carboxylic acids (methacrylic acid and higher homologues).
Patent CA-2654404-C (CA)
Inventor: PARK DOUGLAS A
IPC: G08C17/02
Filed: 2007-05-18
Granted: 2013-04-23
Abstract: A wireless communications system for viewing and modifying memory locations within a power system device includes a wireless device and a power system device. The wireless device includes a user input which accepts a memory location the user wishes to view; a first radio frequency transmitter for transmitting a first signal including the memory location within the power system device the user selected; and a first radio frequency receiver for receiving a second signal. The power system device includes a randomly accessible memory location and a processor coupled to the memory location; a second radio frequency receiver coupled to the processor and a second radio frequency transmitter coupled to the processor for receiving the first signal. The processor retrieves the value of the memory location included within the first signal and activates the second radio frequency transmitter to transmit a second signal including the value of the memory location.
Patent CA-2654850-C (CA)
Inventor: BRUNONE RENE
IPC: B65G15/34
Filed: 2009-02-13
Granted: 2016-04-19
Abstract: The invention concerns a conveyor belt including a longitudinal transportation belt (20) and a plurality of support stations (24) for the transportation belt (20) distributed longitudinally along the said transportation belt (20).  According to the invention, the transportation belt (20) comprises a matrix of an elastic material and an armature embedded in the matrix, and at least some support stations (24) each include the means (44) to support the belt (20) and a chassis (46) resting on the ground, the support means (44) being secured to the chassis (46) at a height of more than two meters relative to the ground. The support stations are very widely spaced.  The conveyor has no means of support for the belt between the stations.
Patent CA-2656238-C (CA)
Title: Housing for a hearing aid, hearing aid, and a method of preparing a hearing aid
Inventor: WESTERMANN SOREN ERIK
IPC: H04R25/02
Filed: 2006-06-20
Granted: 2014-08-19
Abstract: A custom-made BTE hearing aid housing (17) comprises a first part, and a second part, wherein said first part is adapted to fit the contour of the cleft between a pinna and the skull of an individual is provided. The housing may be part of a hearing aid (30), connected with a tube (9) in a first end and an earplug (20) in a second end. The invention also provides a hearing aid and a method of preparing a hearing aid housing.
Patent CA-2658842-C (CA)
Inventor: MCGEER BRIAN T
IPC: B64C25/68
Filed: 2007-08-20
Granted: 2013-02-19
Abstract: For retrieval of a hovering aircraft, a cable, bar, or similar fixture is suspended in an approximately horizontal orientation across the retrieval area between two well-separated supports. The aircraft slowly flies into this fixture, which then slides along the aircraft in a direction approximately parallel with the aircraft's thrust line. This leads to the aircraft becoming fastened to the fixture by an interceptor or aircraft capturer which in alternative embodiments are respectively on the aircraft or the fixture or both. Thrust is then reduced, and the aircraft comes to rest hanging from the fixture for subsequent removal. Retrieval is thus accomplished with simple and economical apparatus, light and unobtrusive elements on the aircraft, low risk of damage, and only moderate piloting accuracy.
Patent CA-2662582-C (CA)
Inventor: KODDE ADRIAAN JOHANNES
IPC: B01D53/04
Filed: 2007-09-26
Granted: 2015-09-08
Abstract: The invention provides a process for removal of metal carbonyls from a synthesis gas stream comprising metal carbonyls, the process comprising the steps of: (a) adsorption of metal carbonyls by contacting the synthesis gas stream with solid adsorbent comprising activated carbon and/or hydrophobic zeolite to obtain solid adsorbent enriched in metal carbonyls and a synthesis gas stream depleted of metal carbonyls; (b) desorption of metal carbonyls by contacting the solid adsorbent enriched in metal carbonyls with CO-containing gas comprising at least 0.5 volume% CO to obtain regenerated adsorbent depleted of metal carbonyls and CO- containing gas enriched in metal carbonyls, wherein the temperature at which metal carbonyl desorption takes place is higher than the temperature at which metal carbonyl adsorption takes place.
Patent CA-2663161-C (CA)
Inventor: LETOURNEAU JEFFREY
IPC: C07D403/04
Filed: 2007-09-10
Granted: 2014-10-28
Abstract: The present invention relates to a quinazolinone or isoquinolinone derivative of formula I, wherein R1 is C1-6alkyl, C3-6cycloalkyl, C3-6cycloalkylC1-3alkyl, C2-6alkenyl, C2-6alkynyl, said C1-6alkyl, C3-6cycloalkyl and C3-6cycloalkylC1-3alkyl being optionally substituted with hydroxy, C1-6alkyloxy, cyano or one or more halogens; R2 is C6-10aryl optionally substituted with one to three substituents selected from halogen, hydroxy, cyano, C1-6alkyl, C3-6cycloalkyl, C1-6alkyloxy and C3-6cycloalkyloxy, said C1-6alkyl, C3-6 cycloalkyl, C1-6 alkyloxy and C3-6Cycloalkyloxy being optionally substituted with one or more halogens; or R2 is a 5-10 membered heteroaryl ring system comprising a heteroatom selected from N, O and S and optionally substituted with a substituent selected from methyl, C1-6alkyloxy and halogen; or R2 is C4-7cycloalkyl; R3 is an optional substituent selected from C1-6alkyl, C1-6alkyloxy and halogen, said C1-6alkyl and C1-6alkyloxy being optionally substituted with one or more halogens; R4 is a group located at the 6- or 7- position of the quinazolinone or isoquinolinone ring having the formula Il, wherein R5 together with one of R6 forms a 4-8 membered saturated or unsaturated heterocyclic ring optionally comprising a further heteroatomic moiety selected from O, S and NR9, said heterocyclic ring being optionally substituted with one or two substituents selected from methyl, halogen, hydroxy and oxo or R5 together with one of R7 and R8 forms a 6-8 membered heterocyclic ring optionally substituted with one or two substituents selected from methyl, halogen, hydroxy and oxo; Each R6 is independently H, halogen or C1-4alkyl optionally substituted with halogen or SO2CH3 or one of R6 together with R5 forms a 4-8 membered saturated or unsaturated heterocyclic ring optionally comprising a further heteroatomic moiety selected from O, S and NR9, said heterocyclic ring being optionally substituted with one or two substituents selected from methyl, halogen, hydroxy and oxo; R7 and R8 are independently H, C1-6alkyl, C3-6cycloalkyl, C3-6cycloalkylc1-3alkyl, cyanoC1-3alkyl, C6-10aryl, C6-10arylC1-3alkyl, C1-3alkyloxyC1-3alkyl or C1-6acyl said C1-6alkyl, C3-6cycloalkyl and C3-6cycloalkylC1-3alkyl being optionally substituted with hydroxy, 1 or more halogens or diC1-2alkylamino; or R7 and R8 together with the nitrogen to which they are bonded form a 4-8 membered saturated or unsaturated heterocyclic ring optionally comprising a further heteroatomic moiety selected from O, S and NR10, said heterocyclic ring being optionally substituted with one or two substituents selected from C1-6alkyl, halogen, hydroxy,
Patent CA-2677054-C (CA)
Title: Bouchon mecanique et son procede d'utilisation
Inventor: HEMMINGER MATTHEW
IPC: F16B13/14
Filed: 2008-01-31
Granted: 2015-04-14
Abstract: L'invention concerne un bouchon conçu pour obturer une ouverture formée dans une paroi en béton. Le bouchon comprend une partie de corps principal, une première extrémité et une seconde extrémité, la première extrémité et la seconde extrémité étant combinées par un boulon présentant une pièce de fixation sur une extrémité. Des rondelles sont associées au boulon à chaque extrémité du bouchon. Le bouchon présente un premier diamètre lui permettant d'être inséré dans l'ouverture et un second diamètre lui permettant de boucher l'ouverture dans la paroi. Le bouchon est déplacé de sa première position à sa seconde position par le serrage de la pièce de fixation, comprimant ainsi le bouchon entre les deux rondelles. Ce serrage entraîne une expansion du bouchon dans sa seconde position, augmentant son diamètre à l'intérieur de l'ouverture et formant un joint d'étanchéité entre le bouchon et la paroi de l'ouverture.
Patent CA-2678987-C (CA)
Inventor: PUCHHAMMER GREGOR
IPC: A61F2/68
Filed: 2008-02-21
Granted: 2014-07-08
Abstract: L'invention concerne une prothèse dotée d'un accumulateur d'énergie électrique (12), cette prothèse comportant une bobine d'induction (28) et une connexion de charge (24) électriquement reliée à la bobine d'induction (28) et à l'accumulateur d'énergie électrique (12) pour charger ledit accumulateur d'énergie électrique (12) sur la base d'un courant électrique induit dans la bobine d'induction (28).
Patent CA-2679070-C (CA)
Title: Oligomer-antihistamine conjugates
Inventor: RIGGS-SAUTHIER JENNIFER
IPC: A61K31/496
Filed: 2008-03-12
Granted: 2016-04-26
Abstract: The invention provides antihistamine drugs that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the antihistamine drug not attached to the water-soluble oligomer.
Patent CA-2679533-C (CA)
Inventor: ZUBIATE BRETT
IPC: B25J17/00
Filed: 2008-02-27
Granted: 2016-06-14
Abstract: A steerable multi-linked device may include a first multi-linked mechanism and a second multi-linked mechanism. At least one of the first multi-linked mechanism and the second multi-linked mechanism may include a first link, a plurality of intermediate links, a second link movably coupled to a second one of the intermediate links and a reinforcing member. A first one of the intermediate links may be movably coupled to the first link, and the reinforcing member may extend from a first end of a third one of the intermediate links toward a second end of the third one of the intermediate links.
Patent CA-2680246-C (CA)
Title: Piperazinyl-propyl-pyrazole derivatives as dopamine d4 receptor antagonists, and pharmaceutical compositions containing the same
Inventor: KONG JAE YANG
IPC: A61P25/00
Filed: 2007-07-13
Granted: 2012-03-20
Abstract: The present invention relates to a novel piperazinyl-propyl-pyrazole derivative represented by formula 1, a method of its preparation and a pharmaceutically acceptable composition comprising the same. The novel piperazinyl-propyl-pyrazole derivative of the present invention has superior selective affinity for dopamine D4 receptor, can effectively inhibit psychotic behavior (cage climbing) induced by apomorphine, and has relatively low adverse effects in mouse rotarod test. Therefore, it can be developed as a therapeutic agent for the treatment and prevention of central nervous system (CNS) disorders, in particular, schizophrenia, attention deficit hyperactivity disorder, depression, stress diseases, panic disorder, phobia, obsessive-compulsive disorder, posttraumatic stress disorder, cognitive disorder, Alzheimer's disease, Parkinson's disease, anxiety, paraphrenia, mania, seizure disorder, personality disorder, migraine, drug addiction, alcohol addiction, obesity, eating disorder, and sleeping disorder.  (see formula 1)
Patent CA-2680621-C (CA)
Inventor: HOLT GERALD E
IPC: A21C3/04
Filed: 2009-09-24
Granted: 2016-11-08
Abstract: A system and method for extrusion of dough is disclosed. The system includes an auger for moving the dough; a metering pump comprising an input; a first motor for actuating the auger to transfer dough to the input of the metering pump; a first encoder for reading a position or speed of the first motor and for transmitting a signal associated with the position or speed of the first motor; and a controller configured to receive the signal from the first encoder to control operation of the first motor. The controller operates the first motor to at least partially counteract a variance in a pressure of dough at the metering pump based signals from the encoder and/or the pressure sensor.
Patent CA-2681962-C (CA)
Inventor: BANDYOPADHYAY REBANTA
IPC: A61K9/08
Filed: 2002-01-22
Granted: 2012-06-12
Abstract: A process for formulating certain epothilone analogs for parenteral administration is disclosed wherein the analog is dissolved in a mixture of at least 50% by volume tertiary-butanol in water, the mixture is lyophilized, the resulting lyophilized product is packaged in one vial with a sufficient amount of solvent comprising anhydrous ethanol and a suitable nonionic surfactant in a second vial. All steps are carried out with protection from light. In use, the contents of the second or diluent vial are added to the lyophilized product and mixed to constitute the epothilone analog and the resulting solution is diluted with a suitable diluent to produce a solution for intravenous injection containing the epothilone analog in a concentration of from about 0.1 mg/mL to about 0.9 mg/mL. A preferred surfactant is polyethoxylated castor oil and a preferred diluent is Lactated Ringer's Injection.
Patent CA-2686623-C (CA)
Inventor: STRAUB HENRY CHARLES JR
IPC: G01F1/66
Filed: 2008-05-06
Granted: 2013-07-02
Abstract: Systems and methods of a transducer having a plastic matching layer. At least some of the illustrative embodiments are transducers comprising a housing (having a proximal end, a distal end and an internal volume, the housing configured to couple to a spoolpiece of an ultrasonic meter), a plastic matching layer that has an external surface and an internal surface (the plastic matching layer seals to and occludes the distal end of the housing), and a transducer element abutting the internal surface of the plastic matching layer.
Patent CA-2688923-C (CA)
Inventor: LADOUCEUR NORMAN MINER
IPC: H05K5/02
Filed: 2009-12-18
Granted: 2017-01-17
Abstract: A multiple-fold portable electronic device is provided. The portable electronic device in one embodiment includes a first, second and third planar sections. The first and second planar section are connected by a first joint and foldable in relation to each other. The second and third planar sections are connected by a second joint and foldable in relation to each other. Each planar section can include an input device or an output device or both.
Patent CA-2692189-C (CA)
Title: Article moule resistant a la chaleur et aux chocs
Inventor: KITORA SHUICHI
IPC: B29C49/08
Filed: 2008-05-27
Granted: 2014-03-25
Abstract: La présente invention concerne un article moulé en résine à base d'acide poly-L-lactique présentant des propriétés remarquables en termes de résistance à la chaleur et aux chocs associés aux chutes. L'invention concerne plus précisément une résine obtenue par mélange d'une charge fonctionnelle, formée par copolymérisation de 1 à 100 molécules d'acide D-lactique et d'un polymère de faible poids moléculaire choisi dans le groupe constitué des glycols, des polyesters aliphatiques et des polyesters aromatiques avec un composé comportant des groupes 2-4-hydroxy, pour obtenir une résine à base d'acide poly-L-lactique. Un article moulé constitué de ladite résine présente une remarquable résistance aux chocs associés aux chutes sans rien perdre de sa résistance à la chaleur.
Patent CA-2692606-C (CA)
Title: Inhalable solid amorphous particles comprising tiotropiium bromide and a co-solid
Inventor: ZENG XIAN-MING
IPC: A61P11/06
Filed: 2008-07-03
Granted: 2014-04-01
Abstract: This invention relates to an inhalable medicament and in particular to a solid-state form of tiotropium bromide, namely solid amorphous particles comprising an intimate admixture of tiotropium bromide together with a pharmaceutically accept-able co-solid having a glass transition temperature of at least -50°C, such as a sugar and/or a sugar derivative.
Patent CA-2693023-C (CA)
Title: Vertical direction adjustment tool for downhole drilling apparatus
Inventor: TULLOCH RORY MCCRAE
IPC: E21B7/08
Filed: 2008-06-20
Granted: 2016-02-02
Abstract: A direction adjustment tool (2) for a downhole drilling apparatus is disclosed. The tool has a tubular housing (8) adapted to be incorporated into a downhole drilling apparatus, and steering blades (10) mounted to the housing. A drive shaft (16) transmits drive to a drill bit of a drilling apparatus, wherein the shaft defines a passage for transmitting drilling fluid to the drill bit.  A first pressure chamber (32) is defined between the housing and the shaft and communicates with the passage, wherein the steering blades are moved from retracted positions to extended positions thereof as a result of increase of fluid pressure the first pressure chamber. A pendulum member (54) is pivotably mounted to extend in a vertical orientation when the shaft is not rotating relative to the housing, and pistons (60) prevent movement of at least one steering blade to the extended position thereof as a result of the angle between a longitudinal axis of the shaft and the longitudinal axis of the pendulum member exceeding a predetermined amount.  This causes at least one steering blade to adjust the direction of drilling of the drilling apparatus towards a vertical direction and/or to resist movement of the direction of drilling away from a vertical direction.
Patent CA-2697563-C (CA)
Inventor: PEGLION JEAN-LOUIS
IPC: C07D223/16
Filed: 2010-03-24
Granted: 2012-05-15
Abstract: The invention relates to a novel method for synthesizing a compound of formula VIII: (See formula VIII). The invention relates specifically to a method for synthesizing ivabradine of formula (I): (see formula I) and its addition salts with a pharmacologically acceptable acid and its hydrates. The invention also relates to a compound of formula (X) in a racemic or optically active compound: (see formula X).
Patent CA-2701208-C (CA)
Inventor: RITT STEFAN
IPC: G11C27/04
Filed: 2008-09-02
Granted: 2015-02-03
Abstract: The present invention represents a technique to reduce the readout time of switched capacitor array (SCA) circuitries.  A possible implementation is a SCA chip capable of sampling 12 differential input channels at a sampling speed of 10 MSPS to 5 GSPS. The analog waveform can be stored in 1024 sampling cells per channel, and can be read out after sampling via a shift register clocked at 33 MHz for external digitization. The write signal for the sampling ceils is generated by a chain of inverters (domino principle) generated on the chip. The domino wave is running continuously until stopped by a trigger. A read shift register clocks the contents of the sampling cells either to a multiplexed or to individual outputs, where it can be digitized with an external ADC. It is possible to read out only a part of the waveform for reducing the digitization time. The high channel density, high analog bandwidth of 450 MHz, and low noise of 0.35 mV (after offset calibration) makes this chip ideally suited for low power, high speed, high precision waveform digitizing. Fabricated on an advanced CMOS process in a radiation hard design, the present chip is available in a 64-lead low profile quad flat pack (LQFP) and a 64-pin quad flat non-leaded package (QFN).
Patent CA-2703179-C (CA)
Inventor: LI XINGONG
IPC: A61K31/70
Filed: 2008-10-23
Granted: 2016-06-07
Abstract: The present disclosure relates in part to liposomal vancomycin compositions having low lipid to drug ratios and high concentration of vancomycin. The present disclosure also relates in part to methods of making such compositions.
Patent CA-2703536-C (CA)
Inventor: OLIVER SCOTT
IPC: E02D27/32
Filed: 2010-05-11
Granted: 2016-03-08
Abstract: A foundation system for supporting a manufactured building having a support beam, comprising a ground pan having a planar surface received on a ground surface and a thermally insulative member disposed on the ground pan, which cooperatively define in situ a proximate thermally isolated ground column, with a foundation support connected to the ground pan and to the support beam, the thermally insulative member restricts communication of heat from the proximate thermally isolated ground column below the ground pan for resisting frost heaving. A method of resisting frost heave of a foundation is disclosed.
Patent CA-2711103-C (CA)
Title: Methods of preparing quinazolinone derivatives
Inventor: HANSEN HENRIK C
IPC: C07D239/91
Filed: 2009-06-24
Granted: 2016-08-09
Abstract: The present disclosure relates to methods for preparing compounds, which are useful for regulating the expression of apolipoprotein A-I (ApoA-1), and in the treatment and prevention of cardiovascular disease and related disease states, including cholesterol- or lipid-related disorders, such as, for example, atherosclerosis.
Patent CA-2713103-C (CA)
Inventor: GHOSH ABHRAJIT
IPC: G01S5/02
Filed: 2009-01-22
Granted: 2014-04-22
Abstract: Embodiments of the present invention disclose a secure localization infrastructure using transmitters that can transmit messages at multiple distinct power levels throughout a community of reference points. Transmitters send messages at different power levels in a manner that every location in the system corresponds to a unique set of messages. Received messages are reported back to the localization infrastructure, which then determines location by comparing the messages reported.
Patent CA-2713349-C (CA)
Inventor: JONGREN GEORGE
IPC: H04B7/06
Filed: 2008-05-07
Granted: 2016-07-19
Abstract: Data is transmitted over multiple input multiple output (MIMO) channels.  Plural bit streams are modulated into multiple data symbol vectors. Each vector has a transmission rank with one vector for each MIMO channel. Transmission rank is the number of elements in a data symbol vector corresponding to the number of data streams being transmitted in parallel over each MIMO channel. The multiple data symbol vectors are preceded into multiple precoded symbol vectors using a plurality of precoder cycling sets, one set for each transmission rank including multiple different precoders. The precoders in each precoder cycling set are well-separated with respect to a plurality of distance measures. The precoding includes precoding each data symbol vector of a transmission rank with a precoder belonging to the precoder cycling set of that transmission rank. The precoded symbol vectors are then transmitted over the MIMO channels.