baber/WOPTO huggingface dataset:
Patent AU-2019206116-A1 (AU)
Title: Novel lipids and compositions for the delivery of therapeutics
Inventor: MANOHARAN MUTHIAH
IPC: A61K47/00
Filed: 2019-07-19
Abstract: NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS Abstract: The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structure (I) wherein R, and R2 are each independently for each occurrence optionally substituted Cio-C 30 alkyl, optionally substituted C1 0 -C 30 alkenyl, optionally substituted C 10-C30 alkynyl, optionally substituted C1 0-C 30 acyl, or -linker-ligand; R3 is H, optionally substituted C1 -Cio alkyl, optionally substituted C2 -C1 0 alkenyl, optionally substituted C2-Cio alkynyl, alkylheterocycle, alkylphosphate,alkylphosphorothioate,alkylphosphorodithioate,alkylphosphonates,alkylamines, hydroxyalkyls, w-aminoalkyls, (o-(substituted)aminoalkyls, o-phosphoalkyls, to o thiophosphoalkyls, optionally substituted polyethylene glycol (PEG, mw 100-40K), optionally substituted mPEG (mw 120-40K), heteroaryl, heterocycle, or linker-ligand; E is 0, S, N(Q), C(O), N(Q)C(O), C(O)N(Q), (Q)N(CO)O, O(CO)N(Q), S(O), NS(0) 2N(Q), S(0) 2 , N(Q)S(0) 2 , SS, O=N, aryl, heteroaryl, cyclic or heterocycle; and, Q is H, alkyl, o-aminoalkyl, o-(substituted)aminoalkyl, o-phosphoalkyl or o-thiophosphoalkyl. Figure t. R P= 0 n=i1AO X= NH(CO), {CO)NH, NH(CO)O O(CO)NH, 0, NH(CO)NH, S-S = COH,.-(C- 2)1 0 -, Y= (CA 1)R- Ga(NAc, Mannose, Lactose, Glucose, Fucose Y= (CH2)- (GalNAc), (Mannose)2 ,(Lactose)2 , (Glucose) (Fucose)2 Y= (CH2)n- (GalNAc), (Mannose),(Laose) 3.(Glucose), (Fucose), Y= (CH 2CrO)-GaNAc, Mannose, Lactose, Glucose, Fucose Y= (CHrCHrO)a- (GaINAc)2 , (Mannose)h,(Lactose, (Glucosa)2 , (Fucose)a Y= (C(4-lCH 2 O)a- (GaNAc) 3, (Mannose),( Lactose), (GkRcose), (Fucose) 3 n ~n= 1-10 X= N(CO),(CO)NF.fl)O O(CO)NH 0, NH(CO)NH, -S Y= (CI)n- GalNA, Mannose, Laclose, Glucose, Fucose Y= (CH12)n-IGalNAc), (Mannose),.(Lactose), (Glucose 2, (Fucosez Y= (CH)n- (GNAc)3, (Manrosa),(Lacose)3 , (Grucoseh, (Fucose)3 Y= (C142-CH 2-)a- GANAc, Mannose, Lartoss, Glucose, Fucoen Y= (CH-Crl2-0)a- (GalNAc) (Mannose)z,(Lactose, (Glucose) 2 (Fucase) Y= (C-H2 -rO)a- (GaINAc), (Mannose),(Lactose)3.(Glucose), (Fucose)3 a - 1-100
Patent AU-2019212443-A1 (AU)
Title: Device for supporting a saxophone
Inventor: GRANIC MATEO
IPC: G10G5/00
Filed: 2019-01-22
Abstract: The invention relates to a device (13) for supporting a saxophone (30) on the body of a saxophonist, said device consisting of a rod, the first end of which has a mechanical adapter for connection to the saxophone, a second end of the rod being connected to a plate via a ball joint or a universal joint, and the mechanical adapter comprising an impact pad as a protection against the impact of mechanical parts of the saxophone.
Patent AU-2019253968-A1 (AU)
Title: Batch systems and methods for hydrogen gas extraction from a liquid hydrogen carrier
Inventor: FUTERMAN ROMAN
IPC: C01B3/06
Filed: 2019-04-17
Abstract: A system for extracting hydrogen gas from a liquid hydrogen carrier may include a hydrogen gas reactor, a catalyst for facilitating extraction of the hydrogen gas from the liquid hydrogen carrier, and a reservoir for containing the liquid hydrogen carrier and a spend liquid hydrogen carrier. The system may be configured to regulate a flow of liquid hydrogen carrier in and out of the hydrogen gas reactor, to move a catalyst relative to a volume of the liquid hydrogen carrier, and to provide a continuous flow of the hydrogen gas, in response to a demand for the hydrogen gas.
Patent AU-2019257484-A1 (AU)
Title: Side break air switch with anti-rolling blade lock
Inventor: RHEIN DAVID ADELBERT
IPC: H01H31/28
Filed: 2019-10-31
Abstract: A high voltage, high current, switching device includes a jaw assembly electrically connected to a first electrical conductor, a housing assembly electrically connected to a second electrical conductor and a blade assembly fixedly attached to the housing assembly at a first end thereof. The blade assembly has an electrically conductive blade contact fixedly attached to a second end distal from the first end. Further, the housing assembly and the blade assembly pivot about a first axis to drive the blade contact into the jaw assembly to close the switch and the blade assembly is operable to rotate about a second axis perpendicular to the first axis only when the distal end of the blade assembly is seated in the jaw assembly. Thus, the blade does not pivot about its longitudinal axis prematurely, for example, before it is properly seated in the electrical terminal. 11837952_1 (GHMatters) P108570.AU.1 207--
Patent AU-2019261763-A1 (AU)
Title: Method of manufacturing a first cured part and a second cured part
Inventor: OSBORNE MAX MARLEY
IPC: B29C70/36
Filed: 2019-11-07
Abstract: METHOD OF MANUFACTURING A FIRST CURED PART AND A SECONDCUREDPART In a method of producing symmetrical carbon fiber reinforced composite parts, a plurality of sheets of fibrous material configured as a single structure are positioned on a tool surface where the single structure is comprised of a first composite part joined to a symmetric, second composite part. The single structure is infused with resin and cured on the tool surface, producing a single cured structure comprised of a first cured composite part joined to a second cured composite part. The single cured structure is then divided along a dividing plane, producing the symmetric first cured composite part and second cured composite part. POSITIONING FIBROUS MATERIAL 32 ON A TOOL SURFACE 34 OF A TOOL 36, THE FIBROUS MATERIAL 32 HAVING A CONFIGURATION OF A SINGLE STRUCTURE 38, THE SINGLE STRUCTURE 38 COMPRISING A FIRST PART 42 AND A SECOND PART 44 CURING THE FIBROUS MATERIAL 32 PRODUCING A SINGLE CURED STRUCTURE 92, THE SINGLE CURED STRUCTURE 92 COMPRISING A FIRST CURED PART 94 AND A SECOND CURED PART 96 DIVIDING THE SINGLE CURED STRUCTURE 92 INTO THE FIRST CURED PART 94 AND THE SECOND CURED PART 96, THE FIRST CURED PART 94 AND THE SECOND CURED PART 96 BEING SEPARATE PARTS AFTER
Patent AU-2019262104-A1 (AU)
Title: Particulate sampling device and analysis
Inventor: COLLINS LEWIS ALEXANDER
IPC: G01N15/06
Filed: 2019-05-06
Abstract: Disclosed is a sampling device, a sampling system and a method of collecting samples of particulates. Also disclosed a sampling device, a sampling system and a method of generating data associated with the collection of the samples of particulates. Also disclosed is a system and method for analysing the sample data to identify the particulates in the collected samples and their one or more characteristics which may be correlated with the surrounding environment.
Patent AU-2019263389-A1 (AU)
Title: Selectively permeable graphene oxide element
Inventor: ZHENG SHIJUN
IPC: B01D69/12
Filed: 2019-05-02
Abstract: Described herein is a composite comprising a graphene material and a sulfonated polymer material. The graphene/sulfonated polymer composite is coated onto a substrate to provide a selectively permeable membrane. The selectively permeable membranes of the present disclosure provide high moisture permeability and low gas permeability.
Patent AU-2019264805-A1 (AU)
Title: A motor-driven device for handling a plurality of hoses in a fuel dispensing unit
Inventor: LARSSON BENGT
IPC: B67D7/04
Filed: 2019-05-07
Abstract: Device for handling a plurality of hoses (404) in a fuel dispensing unit (400), the device (100, 200) allowing the hose (404) to be pulled out from a hose storage space and return the hose to the hose storage space. In this device (100, 200), a cable element (104) is connected to a motor (102) for feeding and retracting the cable element (104), wherein when the cable element (104) is being retracted, each of the plurality of hoses (404) will be returned to the hose storage space, wherein when the cable element (104) is being fed, each of the plurality of hoses (404) will be allowed to be pulled out from the hose storage space. The cable element (104) is connected to the motor (102) in both ends of the cable element (104).
Patent AU-2019276775-A1 (AU)
Title: Rail transport vehicle electric energy storage and charging system
Inventor: PETER MASON
IPC: B60L5/42
Filed: 2019-06-03
Abstract: A rail transport vehicle electric energy storage and charging system has an energy storage sub-system (200) and a charging system (400) having a charging rail (4) which only charges a vehicle (10) when the rail is covered.The invention also provides a battery-powered rail vehicle having a rail-contacting charging shoe.
Patent AU-2019309168-A1 (AU)
Title: Method of filling at least one degassed drug product into containers and drug product filling device
Inventor: BOEUF JULIEN
IPC: A61M5/00
Filed: 2019-07-26
Abstract: A drug product filling device (110) for filling at least one drug product into containers is proposed. The drug product filling device (110) comprises: a) at least one drug product preparation device (112), the drug product preparation device (112) being configured for preparing the liquid drug product; b) at least one filling station (114) for filling the liquid drug product into the containers, the filling station (114) being fluidically coupled to the drug product preparation device (112); and c) at least one degassing device (116), the degassing device (116) being fluidically interposed in between the drug product preparation device (112) and the filling station (114) and the degassing device (116) comprising at least one membrane (118) for at least partially separating off at least one gas from the liquid drug product.
Patent AU-2019310600-A1 (AU)
Title: Method for treating epilepsy
Inventor: BECHARD JEFFREY PAUL
IPC: A61K31/235
Filed: 2019-07-26
Abstract: In certain embodiments, the present disclosure is directed to methods and uses for treating a mammal having an epileptic seizure disorder or being at risk for having an epileptic seizure disorder, comprising administering certain herein disclosed isolated fenfluramine enantiomers that are surprisingly effective as anti-epilepsy drugs (AEDs), despite having lower anti-seizure potency than fenfluramine racemate, by virtue of also being less cardiotoxic than fenfluramine racemate. Preferred embodiments contemplate treatment of Dravet syndrome; other preferred embodiments contemplate treatment of other epileptic seizure disorders.
Patent AU-2019315314-A1 (AU)
Title: Monitoring expandable screen deployment in highly deviated wells in open hole environment
Inventor: MALBREL CHRISTOPHE
IPC: E21B43/10
Filed: 2019-06-21
Abstract: A method for deploying a sand screen in a borehole penetrating the earth includes: disposing the sand screen in an unexpanded form in the borehole, the sand screen at least partially surrounding a base-pipe; and activating the sand screen in the unexpanded form by applying at least one of an activation fluid and heat to the sand screen causing the sand screen to expand into an expanded form. The method further includes: conveying a downhole tool through the base-pipe, the downhole tool being configured to sense a property derived from at least one of expansion and non-expansion of the sand screen as a function of distance into the borehole to provide sensed data as a function of distance into the borehole; and identifying one of an expanded state and an unexpanded state of the sand screen using the sensed data as a function of distance into the borehole.
Patent AU-2019316505-A1 (AU)
Title: Compositions for transportation and/or cryopreservation of cells and/or tissues
Inventor: PUMPUTIS PATRICK G
IPC: C12N5/071
Filed: 2019-07-26
Abstract: In various aspects, there are provided compositions used for the transportation and/or cryopreservation of cells, tissues or organs. The transportation and/or cryopreservation compositions comprise at least naringenin, a buffering system and a sugar component. In some embodiments, the cells, tissues or organs are human hair follicles, cells derived from human hair follicles or cells derived from urine.
Patent AU-2019331331-A1 (AU)
Title: High gain and large bandwidth antenna incorporating a built-in differential feeding scheme
Inventor: TEHRAN HAMID REZA MEMAR ZADEH
IPC: H01Q1/24
Filed: 2019-08-27
Abstract: The present disclosure relates to a communication method and system for converging a 5
Patent AU-2019394837-A1 (AU)
Title: Wound treatment gel obtainable by combining platelet rich plasma with autologously derived thrombin
Inventor: HADFIELD JANET
IPC: A61K35/19
Filed: 2019-12-06
Abstract: The present invention provides a method of making a wound treatment composition, wherein the method comprises; i) fractionating a whole blood sample into multiple samples including a platelet rich plasma (PRP) sample,a platelet poor plasma (PPP) sample and a erythrocyte sample, wherein the PRP sample has a haematocrit level of 1-10%, ii) processing a portion of the PPP and/or PRP sample to facilitate cleavage of autologous pro-thrombin present in the PPP and/or PRP to produce autologous thrombin, and iii) combining the PRP sample with a portion of the PPP sample and a portion of the thrombin produced in step (ii) to produce the wound treatment composition; wherein step ii) is performed at less than 15 °C. In preferred embodiments the PRP has a haematocrit level of 2 or 8%. Wound treatment compositions produced by the methods are also provided as are compositions for use in treating chronic and acute wounds.
Patent AU-2019397517-A1 (AU)
Title: Battery with liquid temperature controlling system
Inventor: MUNIZ THOMAS P
IPC: B60L53/80
Filed: 2019-12-12
Abstract: A liquid temperature controlling system is used to circulate a temperature controlled liquid between the liquid temperature controlling system and a battery to produce a temperature controlled battery. The battery and the liquid temperature controlling system are detachably coupled at least while the temperature controlled liquid is circulated. The temperature controlled liquid is removed from the temperature controlled battery. The battery and the liquid temperature controlling system are decoupled after the temperature controlled liquid is removed. A charger is used to charge the temperature controlled battery.
Patent AU-2020201242-A1 (AU)
Title: ADENO-ASSOCIATED VIRUS cy.5 (AAVcy.5) SEQUENCES AND RECOMBINANT AAVs COMPRISING SAME
Inventor: GAO GUANGPING
IPC: A61P25/00
Filed: 2020-02-20
Abstract: 1:\fit\nterwoven\NRPortbl\DCC\FMT\161863 12_.doc-18/l2/2017 A method for detecting and isolating AAV sequences in a sample of DNA obtained from tissue or cells is provided. The invention further provides AAV sequences identified by this method, and vectors constructed using these sequences.
Patent AU-2020202217-A1 (AU)
Title: Fire extinguisher with internal mixing and gas cartridge
Inventor: ROUSSEAU HECTOR
IPC: A62C13/74
Filed: 2020-03-27
Abstract: improvements to a portable fire extinguisher (19) are disclosed. The portable fire ctinguisher (19) includes a chamber (22) configured to be filled with fire suppressant aterial (99) and to be pressurized with gas from a pressurized gas cartridge (50), the >rtable fire extinguisher further including a flow path (80) for releasing the fire ippressant material (99) from the chamber (22). The portable fire extinguisher comprises: integral siphon tube (112) having a first tube end coupled to the flow path (80) and a !cond tube end disposed inside the chamber (22); a fluffing arm (120) disposed in the amber (22) and configured to agitate the fire suppressant material (99) in the chamber 2) when the integral siphon tube (112) is rotated , wherein the fluffing arm (120) includes first end coupled to the integral siphon tube (112) and the fluffing arm (120) extends .dially away from the integral siphon tube (112) to an opposite second end inside the amber (22); and a support gusset (116) coupled to the integral siphon tube (112) and to le fluffing arm (120), wherein the support gusset (116) extends radially away from the tegral siphon tube (112) inside of the chamber (22) and supports at least a portion of the offing arm (120).
Patent AU-2020213603-A1 (AU)
Title: Battery pack
Inventor: LOH KEN YONG
IPC: H01M50/502
Filed: 2020-01-14
Abstract: A portable light weight battery pack (1 ) is formed of a pair of end plates (2), a plurality of cells (4) interposed between the end plates (2), and, a plurality of cell links (5). Each end plate (2) includes a first portion (6), and, a bus plate (11 ). The first portion (6) has a first surface (7) and a second surface (8), including, an arrangement of cutouts (9), and, an arrangement of fluid flow apertures (10).The bus plate (11) substantially overlays the first surface (7), and includes an arrangement of cell connection holes (12). An arrangement of fluid flow orifices (13) substantially align with said fluid flow apertures (10). The battery pack (1 ) may typically be used with electric vehicles and road-use assistance, for camping, mining and numerous industry applications.
Patent AU-2020226111-A1 (AU)
Title: Pharmaceutical composition comprising FLT3 inhibitor and hypomethylating agent for treating acute myeloid leukemia
Inventor: BAE IN HWAN
IPC: A61P35/02
Filed: 2020-02-21
Abstract: Provided are a pharmaceutical composition for treatment of acute myeloid leukemia (AML), and a method for treatment of acute myeloid leukemia by using same, the composition comprising an Fms-like tyrosine kinase-3 (FLT3) inhibitor or a pharmaceutically acceptable salt or solvate thereof, and a hypomethylating agent (HMA) or a pharmaceutically acceptable salt or solvate thereof as a therapeutically effective combination.
Patent AU-2020272149-A1 (AU)
Title: Methods and systems for treatment of skin of a subject
Inventor: SÁNCHEZ JAIME JOSÉ ANTONIO
IPC: A61N1/40
Filed: 2020-04-09
Abstract: An apparatus for treatment of a skin of a subject is provided. The apparatus comprises a base, an applicator head which is rotatably mounted with respect to the base around an axis of rotation, and defines a cavity for receiving a portion of the skin of the subject, a drive for rotating the applicator head, and a pump for reducing a pressure in the cavity for sucking the portion of the skin of the subject into the cavity. The applicator head further comprises one or more electrodes, and the apparatus further comprises one or more electrical power sources and a control system for controlling electrical energy supply to the electrodes. A cross-section of the cavity with a plane comprising the axis of rotation is non-constant in rotation. Also disclosed are methods for treatment of the skin.
Patent AU-2020277191-A1 (AU)
Title: Methods for treating or preventing asthma by administering an IL-4R antagonist
Inventor: PIROZZI GIANLUCA
IPC: A61K31/167
Filed: 2020-11-26
Abstract: The invention provides methods for treating or preventing asthma and associated 
conditions in a patient. The methods featured in the invention comprise administering to 
a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor 
(IL-4R) antagonist, such as an anti-IL-4R antibody.
WO 2015/127229 PCT/US2O1S/016852 
E 
' 2 
CM 
SW0 
0 44 2 a2 
ME4 
Fiurk
Patent AU-2020299378-A1 (AU)
Title: Fluid catalytic cracking processes and apparatus
Inventor: CHEN LIANG
IPC: C10G51/02
Filed: 2020-07-01
Abstract: Apparatus and processes herein provide for converting hydrocarbon feeds to light olefins and other hydrocarbons. The processes and apparatus include a conventional riser reactor in combination with a mixed flow (e.g., including both counter-current and co-current catalyst flows) fluidized bed reactor designed for maximizing light olefins production. The effluents from the riser reactor and mixed flow reactor are processed in a catalyst disengagement vessel, and the catalysts used in each reactor may be regenerated in a common catalyst regeneration vessel. Further, integration of the two-reactor scheme with a catalyst cooler provides a refinery the flexibility of switching the operation between the two -reactor flow scheme, a catalyst cooler only flow scheme, or using both simultaneously.
Patent AU-2020316083-A1 (AU)
Title: Methods and compositions for treating cancer
Inventor: CHEN JIANJUN
IPC: C07C13/573
Filed: 2020-07-23
Abstract: Provided,
Patent AU-2020321067-A1 (AU)
Title: Dihydropyrimidine derivatives and uses thereof in the treatment of HBV infection or of HBV-induced diseases
Inventor: JIANG YIMIN
IPC: C07D417/04
Filed: 2020-07-30
Abstract: Provided herein are dihydropyrimidine derivatives which are useful in the treatment or prevention of HBV infection or of HBV-induced diseases, more particularly of HBV chronic infection or of diseases induced by HBV chronic infection, as well as pharmaceutical or medical applications thereof.
Patent AU-2020329912-A1 (AU)
Title: RNA-guided nucleases and active fragments and variants thereof and methods of use
Inventor: BOWEN TYSON D
IPC: C12Q1/6816
Filed: 2020-08-11
Abstract: Compositions and methods for binding to a target sequence of interest are provided. The compositions find use in cleaving or modifying a target sequence of interest, visualization of a target sequence of interest, and modifying the expression of a sequence of interest. Compositions comprise RNA-guided nuclease polypeptides, CRISPR RNAs, trans-activating CRISPR RNAs, guide RNAs, and nucleic acid molecules encoding the same. Vectors and host cells comprising the nucleic acid molecules are also provided. Further provided are CRISPR systems for binding a target sequence of interest, wherein the CRISPR system comprises an RNA-guided nuclease polypeptide and one or more guide RNAs. Methods and kits for detecting a target DNA sequence are also provided.
Patent AU-2020332005-A1 (AU)
Title: Monocyclic agonists of stimulator of interferon genes sting
Inventor: PETRASSI HANK MICHAEL JAMES
IPC: A61P35/00
Filed: 2020-08-21
Abstract: The invention provides compounds having STimulator of INterferon Genes (STING) agonistic bioactivity that can be used in the treatment of tumors in patients afflicted therewith. The compounds are of formula (IA), formula (I), and formula (II): wherein the various substituents are as defined herein. Ring A is a 5- or 6- membered heteroaryl comprising 1, 2, or 3 N atoms, unsubstituted or substituted with 1, 2, or 3 groups as defined herein. Compounds for practice of a method of the invention can be delivered via oral delivery for systemic exposure, as well as delivered intratumorally. Antitumor therapy using a compound of formula (I) can further comprise administration of an effective dose of an immunecheckpoint targeting drug.
Patent AU-2020332749-A1 (AU)
Title: Method for controlling a train within a train control system, and train control system
Inventor: WIPPLINGER GERHARD
IPC: B61L3/00
Filed: 2020-08-14
Abstract: The invention relates to a method for controlling a train within a train control system, comprising the following method steps - creating an accident model (AccM), wherein accident classes and accident influence factors are determined; - determining a route reservation (RES) specific to the train, comprising a route reservation region and a route profile; - sending a request (A) for releasing the determined route reservation (RES) to a risk analysis device (MAXd); - carrying out a real-time risk analysis for the route reservation (RES) by means of the risk analysis device (MAXd) for at least some of the determined different accident classes, wherein a risk factor (RF) for the route reservation (RES) is determined, and as an outcome it is determined whether the risk factor (RF) is acceptable; - releasing or rejecting the route reservation (RES) depending on the outcome of the risk analysis. The planning, configuration/project planning and approval can thus be simplified and the route utilization can be optimized at a high safety level (safety integrity level SIL4).