baber/WOPTO huggingface dataset:
Patent CA-3034589-A1 (CA)
Inventor: KOSHIMURA YURI
IPC: C07K16/28
Filed: 2017-08-25
Abstract: [Problem] To provide a method for producing a fusion protein obtained by fusing an antibody with a lysosomal enzyme. [Solution] A method for producing a fusion protein obtained by fusing an antibody with a human lysosomal enzyme, wherein the production method includes (a) a step for culturing mammalian cells that produce the fusion protein in serum-free medium to cause the fusion protein to be secreted in the culture broth, (b) a step for recovering the culture supernatant by removing the mammalian cells from the culture broth, and (c) a step for purifying the fusion protein from the culture supernatant using column chromatography in which a material to which is bonded a substance having an affinity for the fusion protein is used as the stationary phase, column chromatography in which a material having an affinity for phosphate groups is used as the stationary phase, and size-exclusion column chromatography.
Patent CA-3035295-A1 (CA)
Inventor: ROTHWELL HOWARD
IPC: A24F40/70
Filed: 2017-09-11
Abstract: In a method of laser welding, a solid metal component is placed in contact with a porous metal component at an interface region, a laser beam is directed onto the solid metal component to cause heating and melting of one or more portions of the solid metal component in the interface region, and the melted metal portions flow into interstices in the porous metal component and then solidify by cooling such that portions of the porous metal component adjacent the said interstices are integrated into the metal of the solid metal component thereby bonding the solid metal component and the porous metal component.
Patent CA-3035412-A1 (CA)
Title: Golf club
Inventor: RICH JOHN W
IPC: A63B53/04
Filed: 2019-03-01
Abstract: A golf club is provided having a hollow shaft, a grip at one end of the shaft, and a hollow club head providing a striking face at an opposite end of the shaft. A  hermetically-sealed, hollow, vacuum chamber in which air and other gases have been evacuated and in which an amount of a fluent weight medium is contained is provided within the golf club and extends continuously within the shaft and club head, such that, during a backswing of the golf club, the fluent weight medium is displaceable from a distal end of the vacuum chamber within the club head to a proximal end of the vacuum chamber within the shaft and during a downswing of the golf club, the fluent weight medium is displaceable from the proximal end of the vacuum chamber within the shaft to the distal end of the vacuum chamber within the club head.
Patent CA-3035651-A1 (CA)
Title: Agent pour regenerer la fonction visuelle ou agent pour empecher la deterioration de la fonction visuelle
Inventor: KURIHARA TOSHIHIDE
IPC: A61K31/7088
Filed: 2017-09-01
Abstract: L'objectif de la présente invention est de fournir un agent pour régénérer la fonction visuelle ou un agent pour empêcher la détérioration de la fonction visuelle, qui aient une excellente capacité de régénération de la fonction visuelle. L'agent pour régénérer la fonction visuelle ou l'agent pour empêcher la détérioration de la fonction visuelle de la présente invention contiennent comme principe actif une protéine chimérique comprenant une séquence d'acides aminés pour un récepteur rhodopsine d'origine microbienne de type pompe à protons et une séquence d'acides aminés pour un récepteur rhodopsine d'origine animale conjugué aux protéines G. La protéine chimérique est de préférence une protéine dans laquelle une séquence d'acides aminés pour une seconde boucle cytoplasmique et/ou une troisième boucle cytoplasmique de la séquence d'acides aminés pour le récepteur rhodopsine d'origine microbienne de type pompe à protons est substituée, ou sont substituées, par une séquence d'acides aminés pour une seconde boucle cytoplasmique et/ou une troisième boucle cytoplasmique du récepteur rhodopsine conjugué aux protéines G.
Patent CA-3035892-A1 (CA)
Inventor: PATEL SHWETAK N
IPC: G01R35/00
Filed: 2011-07-01
Abstract: A method of using a power consumption measurement device, including: determining one or more first magnetic field readings from the one or more main electrical supply conductors using one or more sensors; electrically coupling a first calibration load to the electrical power infrastructure; determining one or more second magnetic field readings from the one or more main electrical supply conductors using the one or more sensors; calibrating the power consumption measurement device using at least in part the one or more first magnetic field readings and the one or more second magnetic field readings; determining one or more third magnetic field readings from the one or more main electrical supply conductors using the one or more sensors; and determining an electrical power used by the electrical power infrastructure of the structure using at least the one or more third magnetic field readings and the one or more first calibration coefficients.
Patent CA-3038378-A1 (CA)
Inventor: COLPAERT FILIP
IPC: C05G3/90
Filed: 2017-10-13
Abstract: The invention relates to a homogeneous, solid, particulate, urea-based composition comprising elemental sulphur and a urease inhibitor of the type phosphoric triamide, wherein the urea-based composition comprising elemental sulphur is further characterized in that one or more of the following measures applies: a) it comprises 5 weight% or less, relative to the total weight of the composition, of one or more alkaline or alkaline-forming inorganic or organic compounds; or b) it comprises an anticaking and/or moisture-repellent coating. The composition according to the invention has improved properties for reducing ammonia loss by urease activity in the soil and is in particular suitable as a fertilizer. The invention further relates to a method for the manufacture of a homogeneous, solid, particulate urea-based composition comprising urea, elemental sulphur and a urease inhibitor of the type phosphoric triamide, in particular N-(n-butyl) thiophosphoric triamide (nBTPT), as well as to a composition of kit of parts comprising: a) one or more alkaline or alkaline-forming inorganic or organic compounds; b) the urease inhibitor of the type phosphoric triamide in solid particulate or a liquid form, preferably wherein the urease inhibitor is N-(n-butyl) thiophosphoric triamide (nBTPT); c) optionally, one or more anticaking and/or moisture-repellent compounds.
Patent CA-3038643-A1 (CA)
Inventor: SANO YASUHITO
IPC: G05D1/02
Filed: 2016-09-27
Abstract: In a self-position estimation method, the relative positions of a moving body and a target present in the vicinity of the moving body are detected, positions obtained by moving the relative positions by the movement amount of the moving body are stored as target position data, target position data is selected on the basis of the reliability of the relative position of the target position data in relation to the moving body, and the selected target position data is compared with map information including the position information of the target present on a road or near a road, whereby the self-position, which is the current position of the moving body, is estimated.
Patent CA-3042393-A1 (CA)
Title: Biocapteurs pour l'analyse biologique ou chimique et leurs procedes de fabrication
Inventor: ZHONG CHENG FRANK
IPC: G01N21/64
Filed: 2017-11-03
Abstract: Selon des modes de réalisation, l'invention concerne un biocapteur amélioré pour l'analyse biologique ou chimique. Selon des modes de réalisation de l'invention, des capteurs d'images à semi-conducteurs complémentaires métal-oxyde (CMOS) à éclairage par l'arrière (BSI) peuvent servir à analyser et à mesurer efficacement la fluorescence ou la chimiluminescence d'un échantillon. Cette valeur mesurée peut servir à aider à identifier un échantillon. Selon des modes de réalisation, l'invention concerne également des procédés de fabrication d'un biocapteur amélioré pour l'analyse biologique ou chimique et des systèmes et des procédés de séquençage d'ADN.
Patent CA-3044121-A1 (CA)
Title: New antimicrobial agents against staphylococcus aureus
Inventor: BIEBL MANFRED
IPC: C12N15/62
Filed: 2017-11-20
Abstract: The present invention relates to the field of antimicrobial agents active against Staphylococcus aureus bacteria. In particular, the present invention relates to polypeptides comprising the CHAP domain of LysK endolysin, the M23 endopeptidase domain of lysostaphin, the cell wall binding domain (CBD) of ALE-1, and a further peptide selected from the group consisting of an antimicrobial peptide, an amphipathic peptide, a cationic peptide, a hydrophobic peptide, a sushi peptide and a defensin. In addition, the present invention relates to nucleic acids encoding such polypeptides, vectors comprising such nucleic acids, and corresponding host cells, compositions and devices. Finally, the present invention relates to applications of the inventive polypeptides, in particular in the pharmaceutical field.
Patent CA-3045813-A1 (CA)
Title: Bacteria removal laser
Inventor: REINHARDT JONAS
IPC: A61N5/067
Filed: 2019-05-10
Abstract: A bacteria removal laser is provided, especially for removing caries bacteria from natural or prosthetic teeth, the prosthetic teeth also being treated via extraoral approach, comprising a gripping handle, a laser radiation source, an application optics having a predetermined radiation exit surface, especially a radiation guide rod through which laser radiation passes, and an energy source such as a mains connection or an accumulator. The laser emits in the wavelength range between 2200 nm and 4000 nm and is especially designed as an Er:YAG laser. The energy output averaged over time is less than 1 mJ/mm2 at the radiation exit surface.
Patent CA-3046102-A1 (CA)
Inventor: SOOKRAJ SADESH H
IPC: C07D305/12
Filed: 2018-02-05
Abstract: The present invention is directed to biodegradable polyester polyol polymers having high bio-based content and methods for producing biodegradable polyester polyol polymers having high bio-based content. In preferred embodiments, ß-lactone monomers may be produced from epoxide and carbon monoxide having high bio-based content. In certain preferred embodiment, the ß-lactone is ß-propiolactone produced from ethylene oxide and carbon monoxide. In certain embodiments, ß-lactones may be polymerized with diols, triols, and polyols to form the biodegradable polyester polyol polymers having high bio-based content. In some embodiments, the biodegradable polyester polyol polymers having high bio-based content may be terpolymers formed from a first ß-lactone, a diol, triol, or polyol, and a second ß-lactone. In some other embodiments, the biodegradable polyester polyol polymers having high bio-based content may be copolymers formed from a polylactone oligomer and a diol, triol, or polyol.
Patent CA-3048036-A1 (CA)
Inventor: SOUZA FABIO E S
IPC: A61K31/194
Filed: 2019-06-26
Abstract: The present invention provides a novel crystalline form of Ribociclib succinate, Ribociclib succinate Form APO-I, comprising Ribociclib succinate, benzyl alcohol and water, compositions thereof, processes for the preparation thereof, and the use of this crystalline form in the treatment of conditions associated with increased CDK4/6 kinase activity, and in particular, cancers, including certain forms of breast cancer.
Patent CA-3051760-A1 (CA)
Title: Medical guide wire securement device
Inventor: PATEL AMAN P
IPC: A61M25/00
Filed: 2019-08-28
Abstract: A medical guide wire securement device for the purpose of securing at least one medical guide wire to a set position as determined by the user. The device encases the guide wire in a secure perimeter while providing enough space in its core to easily facilitate the use of other guide wires, catheters, angioplasty balloons or stents. The device may feature guide wire locking mechanisms to reduce the disturbance guide wires emit to the user. Fixed positioning of the device can be achieved by either clamping the device in place or utilizing an adhesive to secure the device in place.
Patent CA-3055617-A1 (CA)
Title: Streaming parser for structured data-interchange files
Inventor: ROS FERNANDO
IPC: G06F40/221
Filed: 2019-09-16
Abstract: An embodiment may involve a computing system that includes a processor and memory.  The memory may contain program instructions executable by the processor to repeatedly perform, for each block of a textual data-interchange file, operations including:  obtaining a block of the file, where the block contains one or more records each containing one or more elements; identifying any pre-defined elements contained in records that are completed within the block, where the pre-defined elements are specified by a set of paths, the paths each hierarchically defining a location of an element within a record; storing, and into one or more files or one or more database tables, the pre-defined elements contained in records that are completed within the block; and determining whether the block ends with a partial record, and maintaining any such partial record for later storage in conjunction with processing of a subsequent block of the file.
Patent CA-3057459-A1 (CA)
Title: Non-conductive support stands
Inventor: STILWELL Charles Mitchell
IPC: H02G1/14
Filed: 2018-03-20
Abstract: A support stand made of a non-conductive material and having a saddle, pedestal and a base used to support objects is provided. The pedestal supports the saddle and the base supports the pedestal. The saddle has a support member used to support objects and one or more flanges used to support objects. The saddle, pedestal and base are formed of a non-conductive material.
Patent CA-3060162-A1 (CA)
Title: Diffractive grating with variable diffraction efficiency and method for displaying an image
Inventor: VARTIAINEN ISMO
IPC: G02B27/42
Filed: 2018-05-08
Abstract: The invention relates to a diffractive optical grating and applications thereof. The grating comprises a first zone and a second zone each having a two-dimensionally periodic grating structure having a first period (dx) in a first direction, the first period being chosen to allow for diffraction of selected wavelengths of visible light along the first direction, and a second period (dy) in a second direction different from the first direction, the second period (dy) being short enough to prevent diffraction of said selected wavelengths along the second direction. According to the invention, the grating structures in the first zone and in the second zone have different modulation characteristics in said second direction for producing different diffraction efficiencies for the first and second zones.The invention provides a new design parameter, sub-wavelength modulation, for assisting in local adjustment of diffraction efficiency of gratings in particular in display applications.
Patent CA-3060744-A1 (CA)
Title: Controllable micro light emitting diode system and method
Inventor: JOHANNESSEN ERIC
IPC: H05B44/00
Filed: 2019-10-29
Abstract: A variable geometry light source and related method for illumination comprises a dense array of micro light emitting diodes (LED) incorporated within a printed circuit board and controlled by an incorporated microcontroller. The microcontroller receives user input and causes the dense array to illuminate according to the input. A tunable lens operates to focus the LED illumination toward one or more specific target subjects creating a variable geometry light projection. The microcontroller is configured with instructions which cause the dense array to produce a variety of shapes, intensities, and color temperatures tailored to the individual installation.  The microcontroller causes the dense array to create a light projection suitable for illumination of a subject as well as a dynamic projection animated for a communication to the viewer.
Patent CA-3063140-A1 (CA)
Title: Biodegradable microparticles for sustained delivery of anti-angiogenic peptide
Inventor: GREEN JORDAN J
IPC: A61K38/00
Filed: 2018-05-08
Abstract: The present invention provides microparticle compositions comprising antiangiogenic peptides, as well as methods of treatment, including for macular degeneration. In various aspects and embodiments, the present invention provides microparticle compositions providing extended release of anti-angiogenic peptides. The microparticle of the present invention comprises poly(lactide-co-glycolide) (PLGA) having a having lactic acid (LA) to glycolic acid (GA) ratio (LVG) of more than 1:1; the microparticle further comprises, e.g., encapsulates, an anti-angiogenic peptide derived from the a5 fibril of type IV collagen.
Patent CA-3064790-A1 (CA)
Title: An orthodontic device
Inventor: CARRIERE LLUCH LUIS
IPC: A61C7/30
Filed: 2018-05-28
Abstract: An orthodontic device for the segmental distalization of a posterior jawbone area is disclosed. The orthodontic device comprises a mesial element having a mesial base surface for attachment to a premolar or a canine, a projection for coupling with a traction element, and an arm comprising an elongate transverse pin at a distal end of the arm, and a distal base having a distal base surface configured for attachment to a molar, and a receptacle for receiving the transverse pin. A first axis is defined as being substantially perpendicular to the distal base surface, and the transverse pin has a mesial surface and a distal surface, an interior shape of the receptacle is such that the rotation about the first axis is limited by the mesial and/or distal surface touching against an inside of the receptacle. The disclosure also relates to orthodontic kits.
Patent CA-3065523-A1 (CA)
Inventor: VARGEESE CHANDRA
IPC: C12N15/113
Filed: 2018-06-01
Abstract: La présente invention concerne entre autres des oligonucléotides PNPLA3 conçus, des compositions et des procédés associés. Dans certains modes de réalisation, les compositions d'oligonucléotides proposées permettent une interférence d'ARN simple brin améliorée et/ou une inactivation médiée par la RNase H. Entre autres, la présente invention inclut la reconnaissance du fait que des éléments structuraux d'oligonucléotides, tels que la séquence de bases, des modifications chimiques (par exemple, des modifications de liaisons sucre, de bases et/ou internucléotidiques) ou des motifs de celles-ci, la conjugaison avec des fractions chimiques supplémentaires, et/ou la stéréochimie [par exemple, la stéréochimie de centres chiraux du squelette carboné (liaisons internucléotidiques chirales)], et/ou des motifs de celles-ci, peuvent avoir un impact significatif sur des propriétés et des activités d'oligonucléotides, par exemple, l'activité d'interférence d'ARN (ARNi), la stabilité, la distribution, etc. Dans certains modes de réalisation, la présente invention concerne des méthodes de traitement de maladies à l'aide de compositions d'oligonucléotides proposées, par exemple, dans une interférence d'ARN et/ou une inactivation médiée par la RNase H.
Patent CA-3066083-A1 (CA)
Title: N2,n4-diphenylpyrimidine-2,4-diamine derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient for prevention or treatment of cancer
Inventor: LEE KWANGHO
IPC: C07D401/12
Filed: 2018-06-12
Abstract: The present application relates to N2, N4-diphenylpyrimidin-2,4-diamine compounds of Formula 1. The application also includes methods for preparing compounds of Formula 1, pharmaceutical compositions comprising the compounds and to uses thereof, for example, for the prevention or treatment of cancer such as cancer with EGFR mutations or cancer with FLT3 or a mutation thereof. a   (1)
Patent CA-3070943-A1 (CA)
Inventor: KORYAKIN ROSTISLAV
IPC: G06Q30/00
Filed: 2018-07-25
Abstract: Des techniques de validation automatique de la fonctionnalité d'offres dans un système de courtage en services en nuage intègrent un dispositif informatique de validation d'offre configuré pour : identifier des scénarios d'une offre devant être validés; générer une série d'étapes de haut niveau et de paramètres substituables pour les scénarios de l'offre qui correspondent à un progiciel d'application associé à une application en nuage; déterminer une ou plusieurs étapes de bas niveau pour chacun des paramètres substituables; remplacer chacun des paramètres substituables par une ou plusieurs étapes de bas niveau associées correspondantes; et regrouper lesdites une ou plusieurs étapes de bas niveau associées et les étapes de haut niveau générées en un outil de validation utilisable par le système de courtage en services en nuage pour valider automatiquement la fonctionnalité des scénarios de l'offre. La présente invention concerne également d'autres modes de réalisation.
Patent CA-3074933-A1 (CA)
Title: Anticorps presentant une specificite pour btn2 et leurs utilisations
Inventor: OLIVE DANIEL
IPC: A61K38/00
Filed: 2018-09-21
Abstract: La présente invention concerne des anticorps présentant une spécificité pour BTN2 et leurs utilisations, en particulier pour le traitement du cancer.
Patent CA-3074934-A1 (CA)
Inventor: MIRACLE GREGORY SCOT
IPC: C11D3/40
Filed: 2018-10-11
Abstract: A laundry care composition including (a) at least one laundry care ingredient and (b) a compound of Formula (XL). A method of treating a textile comprises the steps of (a) providing such a laundry care composition; (b) adding the laundry care composition to a liquid medium; (c) placing textile articles in the liquid medium; (d) optionally, rinsing the textile; and (e) drying the textile articles.
Patent CA-3075723-A1 (CA)
Inventor: KUMAR SAURABH
IPC: A23B4/20
Filed: 2018-09-11
Abstract: The present invention relates to microbial safety of meat products. In particular new additives are provided for effective reduction of pathogenic bacteria, such as Shiga toxin producing Escherichia coli (STEC), on or in meat products. The present inventors found that a combination of a nonionic surfactant and organic acid is particularly effective in the reduction of these and other pathogenic bacteria in meat products. The addition of a thickening agent was found to further enhance the effectiveness of the compositions in eliminating these pathogenic bacteria. The present invention provides these meat preservation compositions, the methods of treating meat with these compositions, the related uses of these compositions, as well as the meat products accordingly obtained.
Patent CA-3076268-A1 (CA)
Title: Electronic apparatus, method and computer-readable storage medium for wireless communication system
Inventor: ZHANG YUAN
IPC: H04W72/04
Filed: 2018-09-14
Abstract: The present disclosure relates to an electronic apparatus, a method and a computer-readable storage medium for a wireless communication system. The electronic apparatus for a wireless communication system according to the present disclosure comprises: a processing circuit, configured to generate resource allocation information according to interference conditions encountered by user equipment (UE), wherein a current altitude of the UE is higher than an altitude threshold, and sending the resource allocation information to base station equipment of other cells apart from neighboring cells of a current serving cell of the UE, so as to configure information sending resources for the base station equipment of the other cells. The electronic device, method and computer-readable storage medium of the present disclosure are capable of reducing information interference generated in a wireless communication system of an unmanned aerial vehicle device.