baber/WOPTO huggingface dataset:
Patent CA-2211237-A1 (CA)
Inventor: EEK ARNE
IPC: A61M5/14
Filed: 1996-02-12
Abstract: La présente invention concerne une chambre (1) de pompe pour une pompe destinée essentiellement à des systèmes de perfusion à usage médical. Cette chambre de pompe comprend des parois (21, 28) délimitant ladite chambre, une entrée (22) et une sortie (23). Une partie des parois latérales de ladite chambre de pompe est formée par une membrane souple (40, 90), qui peut être actionnée par un moyen d'actionnement (80) à mouvement de va-et-vient qui fait varier le volume de la chambre de pompe. La membrane (40, 90) a la forme d'un dôme convexe saillant de ladite chambre de pompage (1) et est constituée d'un matériau souple et élastique. Ledit moyen d'actionnement agit sur le sommet de la membrane formant un dôme, la course dudit moyen pouvant être ajustée suivant la dose à administrer. L'invention concerne également une valve pour une chambre de pompe.
Patent CA-2211630-A1 (CA)
Title: Peptides for tissue and cell culture media
Inventor: HAKKAART MARCELLINUS JACOBUS J
IPC: C12N5/071
Filed: 1996-02-20
Abstract: The invention relates to a method and culture medium for in vitro culturing eucaryotic cells requiring glutamine, which comprises the use of a protein hydrolysate obtained by enzymatic hydrolysis of a protein material. The protein hydrolysate has a free amino acid level of less than 15 % by weight and the protein hydrolisate have molecular weight below 44 kD. The protein hydrolysate preferably contains at least 20 % of glutamine residues. Also, preferably at least 90 % by weight of the peptides have a molecular weight below 1000 D and the average peptide chain length preferably is below 15 amino acid residues.
Patent CA-2212125-A1 (CA)
Title: Process for producing a protein
Inventor: ROMANDER LENA
IPC: A61K47/48
Filed: 1996-03-01
Abstract: The present invention relates to a substantially endotoxin-free apolipoprotein A (ApoA) or apolipoprotein E (ApoE) and a process for producing the same, by separating the endotoxins from the ApoA or ApoE, or variants or mixtures thereof, by contacting a first aqueous solution containing said ApoA or ApoE with a matrix containing an immobilized compound with an end group comprising two or three nitrogen atoms bonded to a carbon atom, and subsequently treating the matrix containing an immobilized compound with a second aqueous solution containing a surfactant, or by contacting a first aqueous solution containing said ApoA or ApoE with an anion-exchange matrix, and subsequently treating the anion-exchange matrix with a second aqueous solution containing a compound comprising two or three nitrogen atoms bonded to a carbon atom. The invention further relates to use of a matrix containing an immobilized compound comprising two or three nitrogen atoms bonded to a carbon atom and a solution containing a surfactant, or an anion-exchange matrix and a solution containing a compound comprising two or three nitrogen atoms bonded to a carbon atom, for removing endotoxins from aqueous solutions containing ApoA or ApoE, or variants or mixtures thereof. The thus produced ApoA or ApoE can be used for the manufacture of a medicament in the treatment of atherosclerosis and cardiovascular diseases, as well as in a method for treatment of atherosclerosis and cardiovascular diseases when administered in a therapeutically effective amount.
Patent CA-2213337-A1 (CA)
Title: Isolated nonapeptides presented by hla molecules, and uses thereof
Inventor: BOON-FALLEUR THIERRY
IPC: G01N33/574
Filed: 1996-02-01
Abstract: The invention involves nonapeptides by HLA molecules such as HLA-A1. The resulting complexes are identified by cytolytic T cells. Such recognition may be used in diagnostics, or therapeutically.
Patent CA-2214361-A1 (CA)
Inventor: GHOSH SYAMAL KUMAR
IPC: C04B35/48
Filed: 1997-08-29
Abstract: A ceramic article containing a core comprising zirconia and ZrB2 composite wherein zirconia is preferably doped with yttria, and a shell comprising zirconium nitride.
Patent CA-2214926-A1 (CA)
Title: Method for excluding a malfunctioning elementary cell in a membrane electrolyzer or electrochemical generator
Inventor: BRAMBILLA MASSIMO
IPC: H01M8/24
Filed: 1997-09-08
Abstract: The invention concerns membrane electrolyzers suitable for processes such as water or hydrogen halides electrolysis, as well as electrochemical generators fed with gases containing hydrogen and oxygen for direct conversion into electric energy. These apparatuses generally consist of a filter-press assembly of conductive bipolar plates (2), electrodes (4), sealing gaskets (5) membranes (6) and internal longitudinal ducts for feeding the reactants and withdrawing the products and residual reactants. The invention is directed to the method for repairing said electrolyzers or generators when an elementary cell is malfunctioning. This method comprises making at least two perforations in the peripheral area of the bipolar plates (2) and/or gaskets (5) of the malfunctioning cell to reach distribution channels (9, 11) which connect the compartments containing the electrodes (4) with said longitudinal ducts. A sealing means (agent) is then injected through the perforations (12) in order to form suitable occlusions (14, 15) in the distributions channels (9, 11) and in the perforations (12) respectively. To facilitate the perforation procedure, the bipolar plate (2) and/or the gaskets (5) may be provided with blind aid-holes in the peripheral area. Upon sealing the distribution channels (9, 11) and the perforations (12), the bipolar plates (2) delimiting the malfunctioning cell are externally short-circuited and the electrolyzer or generator is ready for operation.
Patent CA-2216599-A1 (CA)
Title: Mdp derivatives and conjugates having haematopoietic function stimulating activity, and compositions containing same
Inventor: CHEDID LOUIS
IPC: A61K38/00
Filed: 1996-04-05
Abstract: A pharmaceutical composition for stimulating the haematopoietic function and preventing the myelotoxic side-effects of some treatments, containing at least one water-soluble muramyl peptide derivative such as Muradimetide, muroctasine or MTP-PE.
Patent CA-2216877-A1 (CA)
Title: Alpha-(substituted alkylphenyl)-4-(hydroxydiphenylmethyl)-1-piperidine butanol derivatives, their preparation and their use as anti-histamines, anti-allergy agents and bronchodilators
Inventor: BROWN PAUL W
IPC: C07D211/34
Filed: 1996-04-16
Abstract: This invention relates to novel substituted piperidine derivatives. More particularly, this invention relates to substituted phenyl 4-substituted-piperidinoalkanol derivatives of formula (I) wherein R1 is -CH3, -CH2OH, -COOH  or -COO-(C1-6)alkyl; and A is hydrogen or hydroxy; the stereoisomers, enantiomers, racemic mixtures thereof or the pharmaceutically acceptable salts thereof; which are useful as anti-histamines, anti-allergy agents and bronchodilators.
Patent CA-2218200-A1 (CA)
Title: Gpi-ceruloplasmin, analogs thereof, and methods of use
Inventor: DAVID SAMUEL
IPC: C12N9/02
Filed: 1997-12-09
Abstract: The present invention  relates to ceruloplasmin having a unique glycosylphosphatidyl-inositol moiety (GPI-ceruloplasmin) and analogs thereof that anchors this form of ceruloplasmin to the cell surface of astrocytes in the mammalian central nervous system (CNS) and to leptomeningeal cells that cover the CNS. The invention also relates to cDNA sequences encoding said GPI-ceruloplasmin, and analogs thereof, and recombinant plasmids and host cells for expression. The invention also provides monoclonal antibodies to the protein, the nucleic acid sequences and their use in diagnosis, research and therapy. The invention further relates to use of said GPI-ceruloplasmin, and analogs thereof, to treat conditions where toxic levels of ferrous iron play a role, such as Parkinsons' disease, Alzheimers' disease, amyotrophic lateral sclerosis, aceruloplasminemia and Hallervorden-Spatz disease.
Patent CA-2219257-A1 (CA)
Title: Sprue gated five layer injection molding apparatus
Inventor: GELLERT JOBST ULRICH
IPC: B65D1/00
Filed: 1997-10-23
Abstract: Sprue gated injection molding apparatus for molding preforms or other products having two layers of a barrier material such as EVOH or nylon alternating between three layers of another thermal plastic material such as PET. The PET is injected by one injection cylinder into first and third melt passages which branch in a front melt distribution manifold to extend to a number of heated nozzles. The first melt passage extends through a central melt channel in each heated nozzle and the third melt passage extends through an outer annular melt channel surrounding the central melt passage to an aligned gate leading to a cavity. The barrier material is injected by another injection cylinder into a second melt passage which branches in a rear melt distribution manifold to extend to an inner annular melt channel extending between the central melt passage and the outer annular melt channel in each heated nozzle. A single control valve mounted in the first melt passage before it branches in the front melt distribution manifold allows separate control of melt flow through each of the three melt passages during the injection cycle.
Patent CA-2219718-A1 (CA)
Title: Opening tab for disposable pull-on diapers
Inventor: SCHMITZ CHRISTOPH JOHANN
IPC: A61F13/551
Filed: 1997-10-30
Abstract: A disposable pull-on diaper (10) comprising an outer surface, an inner surface, a front portion (11), a rear portion (12), a crotch portion (13), each of said front portion (11) and said rear portion (12) having side panels with side edges (14), and overlapping side seams (15) which join together said side panels of said front portion (11) and said rear portion (12) to form leg openings (16) and a waist area, characterised in that at least one side flap (17) is disposed outboard of each of the side edges (14) of said side panels forming the outermost portion of said overlapping side seams (15).
Patent CA-2219781-A1 (CA)
Title: Method and apparatus for adhering object to a glass surface
Inventor: PERECMAN JACK L
IPC: B60R1/04
Filed: 1996-04-18
Abstract: A method and apparatus for quickly and efficiently adhering an object, such as a rear view mirror button, to a glass surface, such as a vehicle windshield. A partial vacuum is created about the object to draw out air bubbles trapped between the object and the glass surface, while heat and pressure are applied to secure the object to the surface.
Patent CA-2220015-A1 (CA)
Title: Azacycloalcane derivatives, preparation thereof and their applications in therapy
Inventor: DEL SOL MORENO GREGORIO
IPC: A61P3/10
Filed: 1996-04-12
Abstract: Azacycloalcane derivatives having general formula (I) wherein R¿1? and R¿2? represent a hydrogen atom, an alkyl group or a phenyl group, or R¿1? and R¿2? form together an oxo group, R¿3? is a hydrogen atom or an alkyl group, or R¿3? forms a methylene group, R¿4? is an aromatic group or, when R¿3? forms a methylene group, R¿4? is a phenylene group of which a carbon atom is bound to Y and another carbon atom adjacent to the former carbon atom is bound to said methylene group, R¿5? is either a group OR¿7? where R¿7? is a hydrogen atom or a benzyl group, or a group N¿4?-methyl-piperazinyl, or else a group NHR¿8? wherein R¿8? is a hydroxyl, pyridinylmethyl or phenylmethyl group, A is an optionally substituted aromatic cycle, n is 1 or 2, X is CH, O or N, and Y is CH¿2?, O or S, their preparation process and their applications in therapy.
Patent CA-2225594-A1 (CA)
Title: Installation de valorisation energetique de dechets urbains et assimiles
Inventor: PEYRELONGUE JEAN-PIERRE
IPC: B09B3/00
Filed: 1998-01-29
Abstract: La présente invention concerne une installation de valorisation énergétique de déchets urbains et assimilés comportant - un dispositif de broyage (1) des déchets dont les refus sont évacués, - un réacteur à lit fluidisé circulant (2) recevant les déchets broyés par une conduite d'alimentation et comportant un lit fluidisé dense latéral situé sur la paroi du réacteur comportant la conduite d'alimentation en déchets broyés, un conduit d'extraction des éléments lourds non fluidisables étant situé à la base de ce lit fluidisé dense latéral et amènant ceux-ci dans un dispositif trieur de grosses particules (3) refroidissant ces éléments et extrayant les matières inertes non fluidisables, les autres matières étant réintroduites dans le réacteur (2), - un agencement de récupération d'énergie et de traitement des fumées sortant dudit réacteur (2). Selon l'invention, au moins une partie desdits refus sont introduits dans ledit dispositif trieur de grosses particules (3).
Patent CA-2225929-A1 (CA)
Title: Convertible kits for a material separating apparatus
Inventor: READ JAMES L
IPC: B07B1/00
Filed: 1996-06-28
Abstract: A convertible vibratory material separating apparatus, and kits (10) to convert the apparatus to a woven-screen or finger-rod upper separating surface. The separating apparatus includes a universal shaker head (20) adapted for vibratory movement within a frame (12) with a tall and short end.  The shaker head (20) includes side plates (32) and a centerplate (48), and removable support rails (62) or plates (92) when the shaker head (20) is converted to finger-rod combs (112) for a separating surface. The shaker head (20) includes flanges (50) on a lateral support tube (42) enclosing an eccentric motor driven shaft (41) and flanges when the shaker head (20) is converted to a woven-screen upper separating surface (60). The kits include right angle flanges (72, 78, 94, and 96), bars and plates (62 and 92) for conversion of the shaker head (20) with woven-screens (132) or combs of finger-rods (112).
Patent CA-2226197-A1 (CA)
Inventor: MURDERS JACK D
IPC: E04F21/24
Filed: 1998-01-06
Abstract: A bull float for working and finishing concrete and the like is provided. The bull float includes a blade. The blade has a first working surface for contacting the work to be troweled. The first working surface has a leading edge and a trailing edge. The blade also has a leading edge member disposed at the leading edge and carries a second working surface disposed at an angle to the first working surface. The blade further includes a trailing edge member disposed at the trailing edge and carries a third working surface disposed at an angle to the first working surface. The bull float includes a planar metal sheet having a front edge and a rear edge, and having its mid area bowed outwardly relative to the working surface. The front and rear edge of the sheet are secured at points fixed with respect to the leading edge and the trailing edge. The sheet exerts uniform opposing bias forces to the leading edge and to the trailing edge of the blade to counteract residual compressive stresses developed on the first working surface during use of the float.
Patent CA-2229277-A1 (CA)
Inventor: SU YE LONG
IPC: F27B3/04
Filed: 1998-02-10
Abstract: A thermal container for preventing heat from escaping from melting metal therein includes a housing, a thermal trough mounted within the housing, a sand layer enclosing the thermal trough, a heat resistant layer enclosing the sand layer, wherein the thermal trough is divided by a partition into a warming chamber, an inlet chamber communicated with the warming chamber, an outlet chamber communicated with the warming chamber, and a temperature measuring chamber communicated with the warming chamber and the outlet chamber.
Patent CA-2229450-A1 (CA)
Title: Methods of reducing or maintaining reduced levels of blood lipids using ob protein compositions
Inventor: PELLEYMOUNTER MARY ANN
IPC: A61P9/12
Filed: 1996-08-02
Abstract: Provided are methods and compositions related to use of OB proteins for treatment of conditions related to blood lipid levels. Such methods and compositions include those useful for the treatment of high cholesterol, high triglyceride levels, arterial plaque, hypertension, and prevention of gall stone formation.
Patent CA-2231900-A1 (CA)
Title: Suction manifolding arterial cylinder blocks and pistons for compressors and pumps
Inventor: DREIMAN NELIK I
IPC: F04B39/10
Filed: 1998-03-12
Abstract: A hermetically sealed reciprocating refrigeration compressor has a suction gas arrangement including a suction gas plenum formed integral with a cylinder block for supplying suction gas directly to a cylinder so as to eliminate the need for external suction gas conduits.      Apertures are formed about the circumference of the cylinder for receiving suction gas directly from the suction gas plenum. Pistons are provided with multiple suction gas entrances and a semi-toroidal suction valve to provide an efficient means of introducing suction gas into a compression chamber during a suction stroke of the compressor. A spherical discharge valve assembly is provided in a valve plate adjacent the compression chamber for improved flow characteristics and increased through flow area.
Patent CA-2233117-A1 (CA)
Inventor: KLUGE EHRHARD
IPC: C22C38/00
Filed: 1998-03-25
Abstract: In a process  for producing a hardened  stainless  steel strip a steel containing 10 to 20% chromium, up to 3% nickel, up to 1.5% molybdenum, up to 1% manganese,  up to 1% silicon, up  to  0.6%  titanium,  up  to  0.1%  carbon  and  up  to  0.1% nitrogen, balance iron and impurities arising from melting, is hot  rolled and  is  then quenched directly  from  the  rolling temperature. To adjust the strength the hot rolled strip may be cold rolled to its final thickness.
Patent CA-2233716-A1 (CA)
Inventor: POMPONI SHIRLEY A
IPC: A61P35/00
Filed: 1996-12-05
Abstract: Novel lactone compounds from the marine sponge Discodermia dissoluta have been isolated. These compounds and their analogs have been shown to have activity against mammalian cancer cells, and can be used in treating human patients which host cancer cells, including leukemia, melanoma, and breast, colon, CNS, and lung tumors.
Patent CA-2235139-A1 (CA)
Inventor: FORLONI ROBERTO
IPC: B32B27/32
Filed: 1996-10-16
Abstract: A heat-shrinkable multi-layer film endowed with good optical and mechanical properties, improved shrinkability and sealability comprising a core layer consisting essentially of a blend of ethylene-propylene copolymer and/or ethylene-propylene-butene-1 terpolymer with polypropylene homopolymer, and two outer layers each comprising a major proportion of a polymeric material selected from the group consisting of ethylene-propylene-butene-1 terpolymers, ethylene-propylene copolymers and blends thereof.
Patent CA-2235398-A1 (CA)
Title: Expression system in microorganism and its use for expressing heterologous and homologous proteins
Inventor: EIJSINK VINCENT G H
IPC: C12N15/74
Filed: 1996-11-13
Abstract: The present invention concerns the discovery of a new regulatory mechanism for gene expression in lactic acid bacteria (LAB), especially Lactobacillus sake LTH673 or Lactobacillus plantarium C11, that includes previously unrecognized strongly regulable promoter elements. The essential finding is that the expression of genes under the control of a promoter element dependent on the expression of the IF-K-R gene cluster. The expression of the IF-K-R gene cluster is autoinduced by the secreted peptide encoded by IF, thus providing a regulable expression system for a desired protein. The invention further comprises the purified IF protein.
Patent CA-2235914-A1 (CA)
Inventor: CURLL BRUCE
IPC: A47B47/00
Filed: 1998-04-24
Abstract: A joint able to join three members.  The joint is formed by each member having at least one channel of a width generally equal to the thickness of a member to be joined to it and a length generally equal to the width of a member to be joined to it.  There is a recess in each member positionable so that, when constructed, the joint has a pathway formed by said recesses.  A locking member is received by said pathway to lock the joint.
Patent CA-2236182-A1 (CA)
Title: Drug-releasing coatings for medical devices
Inventor: DING NI
IPC: A61F2/82
Filed: 1998-04-28
Abstract: The invention is directed to medical devices having a drug-releasing coating and methods for making such coated devices. The coating permits timed or prolonged pharmacological activity on the surface of medical devices through a reservoir concept. Specifically, the coating comprises at least two layers: an outer layer containing at least one drug-ionic surfactant complex overlying a reservoir layer containing a polymer and the drug which is substantially free of an ionic surfactant. Upon exposure to body tissue of a medical device covered with such coating, the ionically bound drug in the outer layer is released into body fluid or tissue. Following release of such bound drug, the ionic surfactant binding sites in the outer layer are left vacant. To maintain the pharmacological activity after delivery of the ionically bound drug, additional amounts of the drug are embedded or incorporated in the reservoir layer in a manner which allows the drug, which is substantially free of ionic surfactants, to complex with the vacant binding sites of the ionic surfactant of the outer layer. As a result, the surface of the medical device is enriched with the drug to provide sustained pharmacological activity to prevent the adverse reaction due to the presence of the medical device. The invention is further directed to medical devices with stabilized drug-releasing coatings. The coatings are stabilized by exposure to a low energy, relatively non-penetrating energy source, e.g., gas plasma or an electron beam energy source.
Patent CA-2237534-A1 (CA)
Inventor: SMITH P A JOEL
IPC: C23C14/24
Filed: 1998-05-13
Abstract: An  evaporated material  detector  can  be  used  as  a pool-height monitor to determine the position of an ingot rod.   The detector is a deposition rate monitor that is positioned so that the deposition is strongly dependent on the pool height position.  The detector can be positioned near the plane of the crucible for surface.  The detector signal gives a strong indication whether the ingot rod is above the crucible surface,  and the position of the rod can be modified so as to position the ingot rod slightly above the top surface of a crucible.  In this way, the rod position  can  be  maintained,  producing  a  more uniform deposition.
Patent CA-2238319-A1 (CA)
Title: Sputtering of lithium using alternating sputtering potential
Inventor: SCHULZ STEPHEN C
IPC: C23C14/34
Filed: 1996-12-05
Abstract: Lithium is sputtered from a target (22) with a metallic lithium surface using an alternating sputtering potential (38) with a frequency between about 8 and about 120 kHz, preferably about 10-100 kHz or using a DC sputtering potential and a reverse cleaning potential applied intermittently. The process can be used to apply lithium to electrochromic materials such as coating on window glass.
Patent CA-2238598-A1 (CA)
Title: Interlining textile comprising yarns of high yarn numbering
Inventor: GROSHENS PIERROT
IPC: D04H13/00
Filed: 1998-05-25
Abstract: The invention relates to an interlining textile intended for the reinforcement of garments or articles of clothing, which is characterised in that it comprises reinforcement and stabilization yarns of high yarn numbering.
Patent CA-2239468-A1 (CA)
Inventor: HEDBERG TORSTEN
IPC: C02F1/24
Filed: 1996-12-06
Abstract: Flotation apparatus (1) for the purification of polluted water, comprising a flotation vessel (3) having an inlet means (23) for supplying polluted water to said vessel, an assembly (41) of spaced elements (43, 65) defining passages for the flow of water through said elements, and outlet means for surface sludge (15, 17) and outlet means (39, 45; 57, 61) for treated water, further comprising flow directing means for forcing the incoming polluted water to reach a level above said assembly (41) and to flow downwardly through said assembly and towards said treated water outlet means (39, 45; 57, 61); and a process for the purification of polluted water by flotation performed in such apparatus.