baber/WOPTO huggingface dataset:
Patent DE-69314673-T2 (DE)
Inventor: OTSUKI TADASHI
IPC: G11B11/105
Filed: 1993-01-28
Granted: 1998-02-19
Abstract: A recording medium in the form of a disc (D) in which locations on said disc (D) other than a predetermined location set as a zero- address are represented by (+) side addresses and (-) side addresses with respect to the zero address, and in which the information concerning these addresses are at least recorded as address data constituted by N bits. With the disc-shaped recording medium the fact that the number of addresses necessary for the radially inner region (ARin) of the disc is lesser than the number of addresses necessary for the radially outer region (ARout) of the disc is utilized in such a manner that the upper four bits of 16 bits are used in the manner of sign bits for representing the addresses on the radially inner side (ARin) of the disc, with the remaining bits being used for representing the addresses, with the 16 bits inclusive of the upper four bits being used for representing the addresses for the radially outer region (ARout) of the disc (D). In this manner, the totality of the tracks may be represented while maintaining interchangeability with the conventional discs even although the track pitch is lesser than in the case of conventional discs. Besides, the address discrimination may also be facilitated. <IMAGE>
Patent DE-69322820-T2 (DE)
Inventor: VRINZEN ALEXANDER PETER MARIE
IPC: A23L27/30
Filed: 1993-08-02
Granted: 1999-08-19
Abstract: The invention relates to a process for the crystallisation of aspartame by neutralising an aqueous solution of aspartame, having a pH of less than 3, with a base and homogenising the solution by means of forced convection, characterised in that the solution is neutralised, and homogenised, in such a manner that the solution obtained is substantially homogeneous and has a pH higher than 3, with the solution no longer being exposed to forced convection at the latest 1 second before crystallisation is visually perceptible.
Patent DE-69326681-T2 (DE)
Inventor: MULLEN SEAN FRANCIS
IPC: H03K3/84
Filed: 1993-04-06
Granted: 2000-02-10
Abstract: A circuit for generating a linear-feedback-shift-register sequence in accordance with a variable characteristic polynomial has multiple stages (102) each including a latch (104), an exclusive-OR gate (108) and a multiplexer (106) for coupling to the input of the latch either the output signal from the exclusive-OR gate or the signal from the preceding stage's latch. The exclusive-OR gate receives as inputs the signal from the preceding stage's latch and an output signal from the complete circuit. The multiplexers are controlled to select which exclusive-OR gates are coupled to their associated latches in accordance with the characteristic polynomial of the desired shift register sequence to be generated. <IMAGE>
Patent DE-69332678-T2 (DE)
Inventor: ROIZMAN BERNARD
IPC: C12N15/869
Filed: 1993-12-22
Granted: 2004-02-05
Abstract: The present invention relates to synthetic herpes simplex virus (HSV) promoters which are constructed by operatively linking the 5' nontranscribed domain of an HSV  alpha  gene to a fragment containing the transcription initiation site and the 5' transcribed noncoding region from an HSV  gamma  gene. Synthetic promoters of the invention that are operatively linked to heterologous genes, inserted into HSV genomes and used to generate live virus are useful for expressing polypeptides encoded by the heterologous genes in appropriate host cells. The synthetic promoters direct transcription of the heterologous genes constitutively throughout the reproductive cycle of the virus at a high cumulative level. The recombinant viruses of the invention can also be used as vaccines to present polypeptides against which a host will mount an immune response.
Patent DE-69333120-T2 (DE)
Inventor: HUBESCH BRUNO ALBERT JEAN
IPC: D06M13/35
Filed: 1993-05-03
Granted: 2004-07-01
Abstract: Compositions are disclosed containing fabric softener compound having two hydrophobic groups attached to the remainder of the compound through ester linkages (DEQA), said compositions being concentrated and containing viscosity/dispersibility modifiers which are single long chain cationic surfactants, highly ethoxylated nonionic surfactants and/or mixtures thereof. Premix mixtures of the DEQA and viscosity modifiers to lower the viscosity of the molten DEQA are disclosed. Processes for making aqueous liquid compositions from solid particulate compositions containing the DEQA and processes of softening fabrics with the compositions are also disclosed.
Patent DE-69402099-T2 (DE)
Inventor: KAIDONIS ARISTIDE
IPC: A62C3/02
Filed: 1994-05-05
Granted: 1997-06-26
Abstract: The device comprises a series of hoses (1) connected together via tees (3) by quick-connection means (2, 4, 5). On the tees are mounted, by screwing, rigid tubes, or poles (10, 11), which have means (15) for spraying droplets at their opposite end. Holding means are used for holding the rigid tubes in the desired position, which is generally vertical. These means may include a support (7), arms (16) or a tripod (17) placed on the ground, or a foot (19) to be implanted in the ground, or magnets (21) mounted on the tube, to be fixed on a suitable metal object already existing. <IMAGE>
Patent DE-69409751-T2 (DE)
Inventor: GUILLEUX EUGENE
IPC: G05D7/01
Filed: 1994-10-24
Granted: 1998-09-17
Abstract: The present invention relates to a device for regulating the flow rate of a fluid material, including an entrance receptacle (1) and an exit receptacle (4) releasing the material at a flow rate regulated by an exit aperture (6), these two receptacles (1, 4) being separated by a common wall (6). The common wall (6) extends from the bottom walls (2, 5) of the receptacles (1, 4) and, above the common wall (6) is located a so-called bell (9) arrangement forming, on either side of the common wall (6), a first (10) and a second (11) intermediate receptacle in which a gas pressure (P) is maintained. <IMAGE>
Patent DE-69417469-T2 (DE)
Inventor: LINDGREN CLAES
IPC: E05F11/06
Filed: 1994-05-10
Granted: 1999-11-18
Abstract: An operator for a window has a chain (2) as an operating member, a sprocket wheel (4) for advancing and retracting the chain (2), and a counterbalancing spring (5) operatively connected to a shaft (9) of the sprocket wheel (4). <IMAGE>
Patent DE-69418641-T2 (DE)
Inventor: METE ANTONIO
IPC: A01M29/00
Filed: 1994-03-29
Granted: 1999-10-07
Abstract: 1. The use of a compound of the general formula    nitrogen atom or a CH group X represents a nitrogen atom or a group CR2 wherein R2represents a hydrogen atom, a nitro group or a substituted thio-methyl group A represents an optionally substituted 5- or 6- membered heterocyclic ring having one or two hetero atoms selected from nitrogen and oxygen, or an optionally substituted aryl, alkenyl or alkynyl group R ,if present, represents a hydrogen atom or an alkyl group and R1represents a 3- or 4- membered alkylene chain optionally interrupted by a nitrogen and/or a sulphur atom, or having a terminal nitrogen and/or sulphur atom, for combating molluscs.
Patent DE-69423730-T2 (DE)
Inventor: HIN TO
IPC: H04L29/06
Filed: 1994-09-01
Granted: 2000-11-16
Abstract: PCT No. PCT/FR94/01032 Sec. 371 Date Apr. 20, 1995 Sec. 102(e) Date Apr. 20, 1995 PCT Filed Sep. 1, 1994 PCT Pub. No. WO95/06991 PCT Pub. Date Mar. 9, 1995This protocol consists in, among other things, updating in all the terminals and in all the nodes of the telecommunication network which a given call concerns a matrix representing the status of each terminal (TA, TB, TC) which is a party to the call in question vis-a-vis each connection (C1, C2, C3) set up for the call in question. This matrix distinguishes a plurality of fine states within the active state of each of the terminals and the nodes that this call concerns. This matrix is generally updated by means of a message which is broadcast throughout the network when an operation is executed in one of the terminals and modifies: the state of this call, or of a connection set up for this call, or of a terminal participating in this call.
Patent DE-69427799-T2 (DE)
Inventor: ANGELUCCI FRANCESCO
IPC: A61K47/48
Filed: 1994-04-08
Granted: 2002-05-02
Abstract: PCT No. PCT/EP94/01100 Sec. 371 Date Dec. 20, 1994 Sec. 102(e) Date Dec. 20, 1994 PCT Filed Apr. 8, 1994 PCT Pub. No. WO94/26311 PCT Pub. Date Nov. 24, 1994The present invention provides polymer-bound anthracyclines of formula A which consists essentially of three units represented by formulae 1, 2 and 3:    <IMAGE>  1   <IMAGE>  2   <IMAGE>  3  wherein: Gly represents glycine; n is 0 or 1; x is from 70 to 98 mol %, y is from 1 to 29 mol %, z is from 1 to 29 mol %, R1 is a C1-C6 alkyl group substituted by one or more hydroxy groups; Y is an amino acid residue or a peptide spacer; [NH-D] is the residue of an anthracycline aminoglycoside [NH2-D]; and Z is a hydroxy group or a residue of formula -NHR1 wherein R1 is as defined above. Methods for their preparation and pharmaceutical compositions containing them are also provided.
Patent DE-69428294-T2 (DE)
Inventor: PEAKE WILLIAM L III
IPC: D04B21/02
Filed: 1994-03-16
Granted: 2002-10-24
Abstract: A lightweight warp knitted textile fabric suitable for use as the loop component of a hook-and-loop fastener is formed of a set of ground yarns knitted in a relatively stretchable construction with a set of loop-forming yarns formed in a stitch pattern producing elongated underlap loops extending outwardly from the technical back of the fabric which can be readily interengaged with the hook elements of a mating hook component without any necessity for brushing, napping or mechanically raising the loops. In one embodiment, a second set of loop-forming yarns is formed in a stitch pattern producing elongated loops extending outwardly from the technical face of the fabric which can be adhered to a backing material such as a carpet backing. In another embodiment, filling yarn is inserted weftwise in every fabric course. The fabric is preferably finished with a starch application to improve handleability during subsequent processing and, in the case of the second embodiment, a fluorocarbon composition is applied when the fabric will be adhered to a foam carpet backing to restrict foam penetration into the fabric interstices.
Patent DE-69428592-T2 (DE)
Inventor: KONNO HIDETOSHI
IPC: B31B50/16
Filed: 1994-07-08
Granted: 2002-05-16
Abstract: In a residual product eliminating apparatus, a liquid food (12) is prevented from flowing out even when a sealed portion (S) is cut at its center. A pair of cutting rails (31, 32) are provided on a cutting jaw (15a), and a cutter (21) is retractably arranged in a gap (33) formed between the respective cutting rails (31, 32). The cutter (21) is advanced to cut packaging materials (11a, 11b). Dollys (31a, 32a) are provided along the respective cutting rails (31, 32). A pair of heating bodies are provided on a heat seal jaw (15b) so as to hold the packaging materials (11a, 11b) between them and the respective dollys (31a, 32a) for sealing. A groove (38) is formed between the respective heating bodies, and a tip end of the cutter (21) moves into the groove (38) at an advanced position of the cutter (21) and pushes the packaging materials (11a, 11b) at a retracted position. Accordingly, there is not produced any region between the packaging materials (11a, 11b) where a residual product is existent. <IMAGE>
Patent DE-69431620-T2 (DE)
Inventor: CHEDID LOUIS
IPC: A61K38/20
Filed: 1994-03-21
Granted: 2003-07-03
Abstract: PCT No. PCT/FR94/00307 Sec. 371 Date Nov. 13, 1995 Sec. 102(e) Date Nov. 13, 1995 PCT Filed Mar. 21, 1994 PCT Pub. No. WO94/21275 PCT Pub. Date Sep. 29, 1994A therapeutical composition for use in humans, comprising a combination of at least one natural or recombinant and preferably human cytokine with at least one muramyl peptide selected from those which, when administered in vivo together with an interferon, also induce an increased in vivo production of an interleukin-1 receptor antagonist IL-1 RA, but preferably do not induce any increase in TNF, IL-8 and IL-1 cytokines. Said composition is useful for antiviral and antitumoral therapies and/or for promoting restoration of the haematopoietic system, particularly in individuals with a weakened immune system.
Patent DE-69435083-T2 (DE)
Inventor: TEKAMP-OLSON PATRICIA A
IPC: C12P21/08
Filed: 1994-09-13
Granted: 2009-03-12
Abstract: Inhibitors, including antibodies, of IL8 binding to its receptors, that interact with the amino-terminal extracellular domain of the IL8 receptor and which compete with IL8 for receptor-binding, are disclosed. The inhibitors are useful modulators of IL8 receptor-mediated biological activity.
Patent DE-69505333-T2 (DE)
Inventor: CONTI PAOLO
IPC: D04B9/56
Filed: 1995-05-12
Granted: 1999-05-06
Abstract: PCT No. PCT/IT95/00072 Sec. 371 Date Jan. 16, 1996 Sec. 102(e) Date Jan. 16, 1996 PCT Filed May 12, 1995 PCT Pub. No. WO95/31595 PCT Pub. Date Nov. 23, 1995A push rod (38) with a pick-up hook (38A) at the end is moved in an axial plane of symmetry to engage by means of the pick-up hook in an intermediate position the partial initial courses (M1) of a pocket (M2) and to bring them progressively to the side opposite the arc of working needles with the progressive formation of the fabric; a body in the form of a shaped annular ring (18), disposed inside the needle cylinder, has a radial slot (22) for said push rod (38) and radial slots (24) in the area opposite said arc of working needles; hooks (60) movable in said slots (24) can be moved from a concealed position to a raised position to make pin-shaped appendages (62) penetrate into the fabric along the initial edge (M1) when this has been brought by the push rod (28) to the side opposite that of the arc of working needles, and subsequently to move the initial comes (M1) progressively up to the needles which are raised and inserted into the fabric to engage said edge (M1).
Patent DE-69505384-T2 (DE)
Inventor: LEEUWEN PETRUS J M VAN
IPC: A61L2/18
Filed: 1995-06-30
Granted: 1999-04-29
Abstract: PCT No. PCT/NL95/00239 Sec. 371 Date Feb. 13, 1997 Sec. 102(e) Date Feb. 13, 1997 PCT Filed Jun. 30, 1995 PCT Pub. No. WO96/00505 PCT Pub. Date Jan. 11, 1996The present invention relates to a method for applying a protective layer to vessels or utensils used in the food industry, such as the milk and meat industries, wherein the vessels or utensils are contacted with an aqueous (natural) soap solution and then rinsed with water. The soap solution used is 2-10 ml, preferable 2-5 ml liquid soap per 100 l water, e.g. mains water. Furthermore, the relevant method is advantageously carried out at a temperature of the range of 10 DEG -40  DEG  C. By using a soap layer as protective layer, the use of disinfectants has become superfluous in the food industry so that the attendant problem of discharging or rendering harmless harmful disinfectants foreign to nature has also been solved.
Patent DE-69505986-T2 (DE)
Inventor: HARBSTER KEVIN
IPC: B01L3/00
Filed: 1995-07-20
Granted: 1999-05-20
Abstract: An integral structure is provided for chemical processing, particularly high-speed mixing and chemical reacting, in which a plurality of laminae are joined together and having inlet and outlet ports connected by a plurality of intersecting channels formed therethrough which accommodate the passage of one or more chemicals, said laminae comprising a material selected for compatibility with the one or more chemicals, the channels being formed so that chemicals are combined at intersections therein at sufficient angles of attack and shear rates so that chemical reactions are not limited by mass transfer. Chemicals are introduced through the inlet ports and processed along the channel, with desirable product withdrawn through the outlet ports. The laminae are selected from material of groups III, IV or V of the Periodic Table. Processes of manufacture of the apparatus and processes utilizing the apparatus are also disclosed herein.
Patent DE-69507620-T2 (DE)
Inventor: HAMMOND TIMOTHY
IPC: C08K5/13
Filed: 1995-09-08
Granted: 1999-09-02
Abstract: PCT No. PCT/GB95/02150 Sec. 371 Date Jun. 16, 1997 Sec. 102(e) Date Jun. 16, 1997 PCT Filed Sep. 8, 1995 PCT Pub. No. WO96/07697 PCT Pub. Date Mar. 14, 1996A polymer composition comprises (a) a stereospecific, preferably fermentation derived, polyester of molecular weight Mw over 100000 consisting of repeating units of formula -O-CmHn-CO- in which n=2m and units with m=3 and m=4 with respectively a C1 and C2 side group on the carbon atom next to oxygen in the polymer chain are copolymerised together, m being 3 in 70-95 mol percent of such units; and (b) at least one alkyl phenol in which the alkyl group preferably contains at least one tertiary carbon atom adjacent to or within 4 carbon atoms of the phenol nucleus. The alkyl phenol may be hindered and may contain a C1-6 alkoxy group para to the phenolic hydroxy group. Suitable alkyl phenols include 2-tert-butyl-4-hydroxy-anisole and alpha- or delta- tocopherol and others usable as antioxidants in foods, oils and polymer systems. The polyester and alkyl phenol and relative proportions thereof are preferably chosen to provide inhibition of crystallisation of the polyester corresponding to an Avrami 'k' parameter less than 0.03.
Patent DE-69511687-T2 (DE)
Inventor: KIRKUP MICHAEL
IPC: C07C227/32
Filed: 1995-03-22
Granted: 2000-03-16
Abstract: Substituted azetidinone hypocholesterolemic agents of the formula   <IMAGE>   or a pharmaceutically acceptable salt thereof, wherein: Ar1 is R3-substituted aryl; Ar2 is R4-substituted aryl; Ar3 is R5-substituted aryl; Y and Z are independently -CH2-, -CH(lower alkyl)- or -C(dilower alkyl)-; A is -O-, -S-, -S(O)- or -S(O)2-; R1 is -OR6, -O(CO)R6, -O(CO)OR9 or -O(CO)NR6R7; R2 is hydrogen, lower alkyl or aryl; or R1 and R2 together are =O; q is 1, 2 or 3; p is 0, 1,2, 3 or 4; R5 is 1-3 substitutes independently selected from -OR6, -O(CO)R6, -O(CO)OR9, -O(CH2)1-5OR9, -O(CO)NR6R7, -NR6R7, -NR6(CO)R7, -NR6(CO)OR9, -NR6(CO)NR7R8, -NR6SO2-lower alkyl, -NR6SO2-aryl, -CONR6R7, -COR6, -SO2NR6R7, S(O)0-2-alkyl, S(O)0-2-aryl, -O(CH2)1-10-COOR6, -O(CH2)0-10CONR6R7, o-halogeno, m-halogeno, o-lower alkyl, m-lower alkyl, -(lower alkylene)-COOR6 and -CH=CH-COOR6; R3 and R4 are 1-3 substituents independently selected from R5, hydrogen, p-lower alkyl, aryl, -NO2, CF3 and p-halogeno; R6, R7 and R8 are hydrogen, lower alkyl, aryl or aryl-substituted lower alkyl; and R9 is lower alkyl, aryl or aryl-substituted lower alkyl; are disclosed, as well as a method of lowering serum cholesterol by administering said compounds, pharmaceutical compositions containing them, the combination of a substituted azetidinone and a cholesterol biosynthesis inhibitor for the treatment and prevention of atherosclerosis, novel intermediates and methods for preparing said intermediates.
Patent DE-69517302-T2 (DE)
Inventor: LINGWOOD CLIFFORD A
IPC: A61K38/16
Filed: 1995-02-20
Granted: 2001-01-18
Abstract: Pharmaceutical compositions comprising known verotoxins, particularly, verotoxin 1, have been found to be useful in the treatment of mammalian neoplasia, particularly, ovarian cancer and skin cancer. Surprisingly, although verotoxin 1 has previously been shown to have anti-neoplastic activity in vitro, non-lethal doses of verotoxin 1 have been shown to be therapeutically anti-neoplastic in vivo.
Patent DE-69518316-T2 (DE)
Inventor: CHU HSIEN-JUE
IPC: A61K39/155
Filed: 1995-05-08
Granted: 2001-03-29
Abstract: The invention provides an improved BRSV vaccine composition, which advantageously provides immunity from infection after a single administration. The composition comprises a modified live BRS virus and an adjuvant, which in combination provide immunity from BRSV infection after a single administration, and elicit an immune response specific to BRSV and including cell-mediated immunity and local (secretory IgA) immunity. In a preferred embodiment, the BRS virus is strain 375, and the adjuvant comprises an unsaturated turpin hydrocarbon, preferably squalene or squalane, and a polyoxypropylene-polyoxyethylene block copolymer, most preferably one where the copolymer has a polyoxypropylene (POP) component with an average molecular weight of about 3250 to 4000 and the polyoxyethylene (POE) component comprises about 10-20% of the total molecule. The adjuvant may optionally include a surfactant, preferably a polyoxyethylenesorbitan monooleate.
Patent DE-69520186-T2 (DE)
Inventor: GUGLIELMI GUIDO
IPC: A61B18/14
Filed: 1995-10-16
Granted: 2001-06-21
Abstract: An apparatus is provided for electrocoagulating blood and tissue at an occlusion site by means of application of an alternating signal or current through a detachable coil (14) on the end of a microcatheter. A Guglielmi Detachable Coil (GDC) is preferably used in the combination with radio frequency energy to cause local heating at the coil. Once carbonization of blood at the detachment zone of the GDC coil occurs, the impedance of the entire system increases. The impedance increase is detected to automatically turn off the alternating current and then to apply a direct current to electrolytically detach the GDC coil from the microcatheter. <IMAGE>
Patent DE-69521608-T2 (DE)
Inventor: VENGE PER
IPC: G01N33/50
Filed: 1995-04-21
Granted: 2002-05-08
Abstract: PCT No. PCT/SE96/00439 Sec. 371 Date Jan. 6, 1997 Sec. 102(e) Date Jan. 6, 1997 PCT Filed Apr. 21, 1995 PCT Pub. No. WO95/29404 PCT Pub. Date Nov. 2, 1995Methods of diagnosing human disease comprise measuring a level of human neutrophil lipocalin (HNL) in a sample from an individual human to be diagnosed. A measured value which is higher than the normal level is an indication that the individual suffers from an inflammation.
Patent DE-69526191-T2 (DE)
Inventor: ARBAB MEHRAN
IPC: C23C14/58
Filed: 1995-12-11
Granted: 2002-10-31
Abstract: A method is disclosed for improving the chemical and mechanical durability of a low emissivity coated article comprising a substrate and a low emissivity coating comprising successive layers of an antireflective metal oxide, an infrared reflective metal, a metal primer and an antireflective metal oxide. The method comprises heating the coated article at a temperature below the strain point of the substrate for a sufficient time and at a sufficient temperature to anneal the coating to reduce structural defects and chemical reactions. Since the temperature is maintained below the strain point of the substrate, annealing the coating to improve its chemical and mechanical durability does not introduce permanent stresses into the substrate, typically glass.
Patent DE-69527346-T2 (DE)
Inventor: NICOLAOU C
IPC: C07D417/12
Filed: 1995-01-11
Granted: 2003-02-13
Abstract: Onium salts of taxo-diterpenoid-Cn,2-O-aza-arenes form water soluble self-assembling nanostructures above a critical aggregation concentration. The onium salt of aza-arene includes a delocalized charge which renders derivatized taxo-diterpenoids amphoteric, enhances their solubility in water, and promotes self-assembly of water soluble nanostructures, e.g., helical fibular structures and spherical micellular structures. These same onium salts of taxo-diterpenoid-Cn,2-O-aza-arenes are employed as water soluble prodrugs. For example, taxol-2'-methylpyridinium tosylate (MPT) is characterized by an elevated aqueous solubility, rapid activation by serum protein, good stability in most other aqueous solutions, formation of a protein:taxol intermediate and good retention within the circulatory system. The toxicity of the activated form is comparable or greater than underivatized taxol. Furthermore, taxol-2'-MPT can be synthesized by a simple one step reaction between taxol and 2-fluoro-1-MPT. The invention is applicable to taxol and taxol memetics having hydroxyls that are reactive with onium salts of 2-halogenated-aza-arenes. For example, taxol, C-2 substituted taxol and Taxotere each have reactive hydroxyls at the 2' and 7 positions. The invention is also applicable to a wide array of 2-halogenated-aza-arenes.