baber/WOPTO huggingface dataset:
Patent JP-3836425-B2 (JP)
IPC: C07C257/18
Filed: 2001-05-29
Granted: 2006-10-25
Abstract: A synthesis method which comprises reacting NH group-containing compounds with thiocyanates, cyanamides, nitriles or esters in the presence of a silylating agent to synthesize the corresponding nitrogen-containing addition or substitution products. This method not only enables the direct and efficient synthesis of nitrogen-containing compounds including isothioureas, guanidines, amidines and amides, but it also has a wide range of applications and is suitable for large-scale synthesis.
Patent JP-4754768-B2 (JP)
IPC: C07C231/24
Filed: 2001-08-31
Granted: 2011-08-24
Abstract: A method for preparing a crystal of 4-Ä(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoylÜbe nzoic acid having a single endothermic peak approximately at 233 DEG C in differential scanning calorimetry, which comprises the step of recrystallizing a crystal of 4-Ä(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoylÜbe nzoic acid from a mixture of water and ethanol. The method enables selective preparation of type-II crystals which are stable against physical impact. The resulting crystals are free from highly toxic hexane as a residual solvent, and preferably used as an active ingredient of pharmaceuticals.
Patent JP-4225057-B2 (JP)
IPC: C07C231/24
Filed: 2001-10-23
Granted: 2009-02-18
Abstract: A method for producing B-type crystals of nateglinide substantially free of H-type crystals is provided, which comprises drying solvated wet crystals of nateglinide at a low temperature until no solvent remains and making a crystal conversion thereof. According to this method, B-type crystals of nateglinide can be produced at an industrial scale without allowing other forms of the crystalline polymorphism to coexist.
Patent JP-4180915-B2 (JP)
IPC: A61J15/00
Filed: 2001-11-03
Granted: 2008-11-12
Abstract: An adapter is connected to a probe tube of a PEG probe that is already in place, the probe tube being cut off above the abdominal wall of the patient. The adapter comprises an outer retaining element, which is supported on the abdominal wall, and comprises structure for fastening the proximal end of the PEG probe, and structure for connecting a delivery line to the flow channel. A shut-off element having a rotatable or displaceable closing body is provided for closing the PEG probe. The adapter is characterized by its universal use, simple handleability and small overall height.
Patent JP-4267326-B2 (JP)
IPC: C08G65/329
Filed: 2002-03-21
Granted: 2009-05-27
Abstract: Polymeric prodrugs of the formula: wherein B is selected from the group consisting of OH, leaving groups, residues of amine-containing moieties and a residues of hydroxyl-containing moieties; Y<SUB>1 </SUB>is selected from the group consisting of O, S, and NR<SUB>5</SUB>; M is NR<SUB>3</SUB>, O or S; Ar is a moiety which when included in Formula I forms a multi-substituted aromatic or heteroaromatic hydrocarbon or a multi-substituted heterocyclic group; (m) is zero or a positive integer; R<SUB>1-3 </SUB>and R<SUB>5 </SUB>are independently selected from the group consisting of hydrogen, C<SUB>1-6 </SUB>alkyls, C<SUB>3-12 </SUB>branched alkyls, C<SUB>3-8 </SUB>cycloalkyls, C<SUB>1-6 </SUB>substituted alkyls, C<SUB>3-8 </SUB>substituted cycloalkyls, aryls, substituted aryls, aralkyls, C<SUB>1-6 </SUB>heteroalkyls, substituted C<SUB>1-6 </SUB>heteroalkyls, C<SUB>1-6 </SUB>alkoxy, phenoxy and C<SUB>1-6 </SUB>heteroalkoxy; and R<SUB>4 </SUB>is a polymeric residue; as well as methods of making and using the same are disclosed.
Patent JP-4227857-B2 (JP)
IPC: A61K38/08
Filed: 2003-07-07
Granted: 2009-02-18
Abstract: The present invention provides a novel peptide-type compound which induces secretion of growth hormone and which has the activity of increasing the intracellular calcium ion concentration, wherein at least one amino acid is replaced by a modified amino acid and/or a non-amino acid compound, or a pharmaceutically acceptable salt thereof.
Patent JP-4105626-B2 (JP)
IPC: C12Q1/6876
Filed: 2002-05-29
Granted: 2008-06-25
Abstract: The invention provides assays to determine the relative amount of mitochondrial DNA in a subject, such as a subject undergoing drug treatment. The subject may for example be a human patient undergoing treatment for an HIV infection with a nucleic acid precursor such as a nucleoside or nucleotide analogue. The assays of the invention may include PCR assays, such semi-quantitative or quantitative PCR involving the co-amplification of a mitochondrial sequence and a reference sequence, such as a genomic sequence. Information from such assays may be evaluated to provide a ratio of mitochondrial DNA to nuclear DNA in the cells of the subject.
Patent JP-4444652-B2 (JP)
IPC: C12N15/09
Filed: 2002-07-10
Granted: 2010-03-31
Abstract: Polypeptide conjugates with G-CSF activity comprising a polypeptide having at least one introduced lysine residue and at least one removed lysine residue compared to the sequence of human G-CSF, and which are conjugated to 2-6 polyethylene glycol moieties. The conjugates have a low in vitro bioactivity, a long in vivo half-life, a reduced receptor-mediated clearance, and provide a more rapid stimulation of production of white blood cells and neutrophils than non-conjugated recombinant human G-CSF.
Patent JP-4136931-B2 (JP)
IPC: B31B50/00
Filed: 2002-08-13
Granted: 2008-08-20
Abstract: Machine for the production of flexible material sheets comprising at least one folding unit housing at least one cutting cylinder, to which a suction cylinder is opposed, and a gripping cylinder for transversal folding and/or conveying flat products by suction. A second suction cylinder for a second transversal fold and/or for conveying flat products and a second conveyor cylinder for conveying folded products or flat unfolded products may be associated downstream to said machine.
Patent JP-4278515-B2 (JP)
IPC: H01L31/0236
Filed: 2002-08-28
Granted: 2009-06-17
Abstract: The invention relates to a method for production of a solar cell (10) and said cell. According to the invention, a high efficiency may be achieved, whereby, on the rear side of the solar cell, first and second contacts (26, 28) are arranged on projections (18), or the flanks thereof (20, 22), for collecting minority and majority charge carriers.
Patent JP-4313200-B2 (JP)
IPC: B60S1/38
Filed: 2002-10-02
Granted: 2009-08-12
Abstract: The windscreen wiper consists of a blade (24) pivoted about a transverse axis (T1) on the end of the wiper arm (22) by means of a connector (42) engaging with a U-shaped end (38) of the arm, and an elastically-deformable locking element (60) to hold it in place. It also incorporates a safety clasp in the form of a cap on the end of the wiper arm that can be closed by rotating it about an axis (V1) to prevent the locking element from coming open accidentally.
Patent JP-4105093-B2 (JP)
IPC: B21F23/00
Filed: 2002-09-18
Granted: 2008-06-18
Abstract: An apparatus for making mattress and upholstery spring coils. The apparatus has a wire feeding device and a wire guide adapted to support first and second wires of different diameters. The wire guide is movable to first and second positions to align the first and second wires, respectively, with the wire feeding device. A spring coiling machine is positioned adjacent the wire feeding device. When the wire guide is in the first position, the spring coiling machine receives the first wire of one diameter from the wire feeding device; and the spring coiling machine bends the first wire into a spring coil of a desired diameter and pitch and having a first stiffness. When the wire guide is in the second position, the spring coiling machine receives the second wire of another diameter from the wire feeding device; and the spring coiling machine bends the second wire into a spring coil of the desired diameter and pitch but having a second stiffness.
Patent JP-4540345-B2 (JP)
IPC: B65D/
Filed: 2002-11-07
Granted: 2010-09-08
Abstract: A package ( 10+20+30 ) for contact lenses ( 10 ), especially 'daily-disposable' lenses, in which the overall volume of the package and the internal volumes of the lens-holding cavities ( 20 ) in the package are minimised. The packages are preferably multi-cavity packages, with each cavity holding a single lens and all the lenses being inserted into their respective cavities with a common orientation such that a wearer of the contact lenses has the assurance that a lens can always be retrieved from a cavity in a standard orientation. The internal surface ( 24 ) of a cavity preferably deviates from sphericity by being formed with undulations ( 50 ) to break capillary attraction between the lens and the cavity wall ( 24 ) so aiding extraction of the lens from the cavity. On the instructions of an ophthalmic practitioner, packages of suitable lenses can be made up and dispatched by courier or by post to wearer of the lenses.
Patent JP-4152887-B2 (JP)
IPC: H03M13/15
Filed: 2002-12-03
Granted: 2008-09-17
Abstract: Techniques for efficiently performing erasure-and-single-error correction block decoding on a received block of symbols previously coded column-wise with an (N, K) linear block code and row-wise with an error detection code (e.g., a CRC code). Initially, each row of the received block is marked as either an erased row or an un-erased row. To perform erasure-and-single-error correction block decoding on the received block, a codeword corresponding to a column of the received block containing an undetected symbol error is initially identified. The location of the symbol error in the codeword is then determined based on a particular block decoding scheme and corresponding to the selected (N, K) block code. The row of the received block containing the symbol error is then marked as an erased row. Block decoding may then be performed for the received block with the newly marked erased row containing the symbol error.
Patent JP-4597525-B2 (JP)
IPC: C12N5/06
Filed: 2003-04-08
Granted: 2010-12-15
Abstract: A method for culturing cells in the presence of an alcanoic acid for enhancing protein production.
Patent JP-5433125-B2 (JP)
IPC: A61P29/00
Filed: 2003-02-24
Granted: 2014-03-05
Abstract: This invention relates to the use of folates for producing a pharmaceutical preparation suitable for the prevention and treatment of inflammation and of diseases associated with inflammation, particularly for influencing the inflammation markers C-reactive protein (CRP) and serum amyloid A protein (SAA). The clinical areas of application are all anomalies of the CRP and SAA levels. The invention also relates to pharmaceutical preparations for the prevention and treatment of inflammation and of diseases associated with inflammation, particularly for influencing CRP and SAA levels, characterised in that as an active ingredient it comprises at least one compound which is selected from the group consisting of pteroic acid monoglutamate (folic acid), dihydrofolic acid, 5-formyltetrahydrofolic acid, 5-methyltetrahydrofolic acid, 5,10-methylenetetrahydrofolic acid, 5,10-methenyl-tetrahydrofolic acid, 10-formyltetrahydrofolic acid or tetrahydrofolic acid, polyglutamates thereof, optical isomers thereof, particularly optically pure natural isomers thereof, and mixtures of optical isomers also, particularly racemic mixtures, as well as pharmaceutically acceptable salts thereof also, together with pharmaceutically acceptable active ingredients and adjuvants.
Patent JP-4052596-B2 (JP)
IPC: B62D25/08
Filed: 2004-08-03
Granted: 2008-02-27
Abstract: A structure of removably mounting a tower connecting bar between top surfaces of right and left strut towers by bolts and nuts. The tower connecting bar has a pipe and annular circular plates attached to opposite ends of the pipe. The circular plates are mounted to the top surfaces of the towers by the bolts and nuts. Upper ends of suspension struts are fastened to the top surfaces of the towers by bolts and nuts. The circular plates have through holes for allowing the strut-mounting nuts to escape when the towers and circular plates are mated together. The through holes provide access to loosen the strut-mounting nuts.
Patent JP-4774479-B2 (JP)
IPC: E01C19/44
Filed: 2004-10-29
Granted: 2011-09-14
Abstract: A walk behind rotary trowel (10) is configured to be "dynamically balanced" so as to minimize the forces/torque that the operator must endure to control and guide the trowel. Characteristics that are accounted for by this design include, but are not limited to, friction, engine torque, machine center of gravity, and guide handle position. As a result, dynamic balancing and consequent force/torque reduction were found to result when the machine's center of gravity was shifted substantially relative to a typical machine's center of gravity. Dynamic balancing can be achieved most practically by reversing the orientation of the engine (16) relative to the guide handle assembly when compared to traditional walk behind rotary trowels and shifting the engine (16) as far as practical to the right. This shifting has been found to reduce the operational forces and torque the operator must endure by at least 50% when compared to traditional machines. <IMAGE>
Patent JP-4392345-B2 (JP)
IPC: A23L29/20
Filed: 2003-05-27
Granted: 2009-12-24
Abstract: The invention relates to a food additive, in particular for food products such as dressings, mayonnaises, spreads or other food products having a reduced fat content. The invention further relates to a process for preparing the food additive and to its use in the preparation of food products. It has been found that a method according to the present invention allows the preparation of a food additive suitable for use as a whitener and/or a fat/protein substitute, depending on the manner in which the method is carried out.
Patent JP-4444101-B2 (JP)
IPC: G06F13/38
Filed: 2003-05-21
Granted: 2010-03-31
Abstract: The invention relates to a bus system comprising a first station and a second station coupled by a bus for transferring signals. The bus is arranged to operate according to a protocol in which said first station repeatedly sends requests for data to the second station. The protocol comprises a first mode for transferring the requests in a first request format at a first communication speed and at least a second mode for transferring said requests in a second request format at a second speed. The second station is arranged to receive requests in a mode selected from a group of modes comprising said first and second modes, and is arranged to give a first indication to said first station if it is arranged to operate according to the first mode and a second indication if it is arranged to operate according to the second mode. The first station comprises a processor, a controller, and a translator. The processor is operable to generate request properties for requests in the first request format. The controller is operable to generate the requests in the first request format from the request properties. The controller is also operable to transmit the request in the first format to the second station upon detection of the first indication and to forward the requests to the translator upon detection of the second indication. The translator is also operable to transmit the requests in the second format to the second station.
Patent JP-5685355-B2 (JP)
IPC: A61K38/22
Filed: 2003-07-02
Granted: 2015-03-18
Abstract: The present invention relates to use of GLP-1 or a related molecule having GLP-effect for the manufacture of a medicament for preventing or treating diabetes in a mammal. The amount and timing of administration of said medicament are subsequently reduced to produce a "drug holiday". Practice of the invention achieves effective therapy without continuous drug exposure and without continuous presence of therapeutic levels of the drug. The invention also discloses a method of treating diabetes and related disorders in a mammal by administering glucagon like peptide (GLP-1) or a related molecule having GLP-1 like effect and thereby providing a therapeutically effective amount of endogenous insulin.
Patent JP-4494967-B2 (JP)
IPC: F04D29/043
Filed: 2003-07-04
Granted: 2010-06-30
Abstract: The invention relates to a device for driving a coolant pump (2) for the coolant circuit of an internal combustion engine in a motor vehicle comprising a drive train that encompasses a drive wheel (7), a viscous coupling (11), and a drive shaft (3). The inventive driving device is provided with a second coupling (15) which is embodied as a clutch and can be connected to the drive train parallel to the viscous coupling (11), resulting in increased redundancy and two-step rev control.
Patent JP-4511939-B2 (JP)
IPC: C07D417/12
Filed: 2003-11-13
Granted: 2010-07-28
Abstract: Compound of formula (I) wherein A is selected from pyridin-2-yl or thiazol-2-yl and R1, R2 and R3 are as described in the specification and their use in the treatment or prevention of a disease or medical conditions mediated through glucokinase.
Patent JP-3672305-B2 (JP)
IPC: B23B41/00
Filed: 2005-01-24
Granted: 2005-07-20
Abstract: There are provided an expanded hole drilling device, a component for the expanded hole drilling device, and an expanded hole drilling method, capable of expanding the diameter of a previously bored hole to a large diameter without causing decentering. The expanded hole drilling device 10 includes a drill holder 22 that is attached to a drill grasping part 18 in place of a drill 16 and grasps the drill 16, and a centering attachment 24 having a conical tip end part, which is attached to the drill holder 22. The expanded hole drilling method includes a step of arranging a bored workpiece displaceably on a table 14, a step of performing centering by inserting the tip end part of the centering attachment 24 into a bored hole, a step of fixing the centered workpiece on the table 14, and a step of drilling the workpiece to expand the hole by using the drill 16 after the centering attachment 24 has been removed.
Patent JP-4961707-B2 (JP)
IPC: C08F2/38
Filed: 2005-09-29
Granted: 2012-06-27
Abstract: <P>PROBLEM TO BE SOLVED: To provide a method for efficiently synthesizing a polymer (a resin) having a narrow molecular weight distribution, and having a content of an introduced compound derived from a prescribed monomer larger than a prescribed value under good control in a short time at a high yield.  <P>SOLUTION: The method for synthesizing the resin involves regulating the boiling point of (D) an organic solvent so as to be ≥120°C in the polymerization of a system comprising (A) an ethylenically unsaturated monomer, (B) a radical source, (C) a molecular weight regulator of a thiocarbonylthio compound, and (D) the organic solvent.  <P>COPYRIGHT: (C)2007,JPO&INPIT
Patent JP-5187710-B2 (JP)
IPC: G01L17/00
Filed: 2005-10-11
Granted: 2013-04-24
Abstract: An assembly for attaching detection unit, in particular for detecting tire pressure, to rim, includes a detection unit receiving detection components; a valve body; a sealing mechanism for providing a seal between the valve body and the rim; a mechanism for holding the valve body in position on the rim; and a module for connecting detection unit to valve body. An assembly (M) of a detection unit (100) inside a tire attached to the body (300) of a valve (V), comprises a detection unit receiving detection components, and a valve body. The tire has a rim. A sealing mechanism (400) is included for providing a seal between the valve body and the rim (200). A mechanism (500) is provided for holding the valve body in position on the rim which is preformed with a connection aperture (210). A module is provided for connecting the detection unit to the valve body. At least one of the elements of the assembly, aside from the sealing mechanism, is preformed so that a portion of this element penetrates the connection aperture to engage it when the assembly is subjected to tangential stresses.
Patent JP-4917331-B2 (JP)
IPC: G02B21/36
Filed: 2006-03-01
Granted: 2012-04-18
Abstract: In acquisition of a micro image of a sample S by a micro image acquiring unit 30, when a plurality of image acquiring ranges are set for the sample S as an object of image acquisition, a plurality of corresponding focus information are set, and furthermore, when a plurality of partial images acquired by scanning the sample S by the micro image acquiring unit 30 include a partial image including mixing of a plurality of image acquiring ranges, the focus information is switched in the middle of scanning of the partial image. With such a structure, even when a plurality of objects are contained in the sample S, images of the respective objects can be preferably acquired. Thereby, an image acquiring apparatus, an image acquiring method, and an image acquiring program which are capable of preferably acquiring images of a plurality of objects are realized even when the plurality of objects are contained in a sample S.
Patent JP-4887908-B2 (JP)
IPC: G08B25/10
Filed: 2006-05-26
Granted: 2012-02-29
Abstract: <P>PROBLEM TO BE SOLVED: To quickly respond to first users and achieve smooth task implementation by second users.  <P>SOLUTION: A portable transmitter/receiver 20<SB>m</SB>, in response to receiving a radio signal transmitted from a wireless transmitter 10<SB>n</SB>, displays on a display part 30 symbol information visually identifying the wireless transmitter 10<SB>n</SB>, which is associated with identification information included in the radio signal, and enables a voice call through a voice input part 32, a radio transmission part 22, a radio reception part 23 and a voice output part 37.  <P>COPYRIGHT: (C)2008,JPO&INPIT
Patent JP-5001637-B2 (JP)
IPC: H01L23/48
Filed: 2006-12-21
Granted: 2012-08-15
Abstract: A semiconductor device package is formed of DBC in which thinned MOSgated and/or diode die are soldered to the bottom of an etched depression in the upper conductive layer. A via in the insulation layer of the DBC is filled with a conductive material to form a resistive shunt. Plural packages may be formed in a DBC card and may be separated individually or in clusters. The individual packages are mounted in various arrays on a support DBC board and heat sink. Integrated circuits may be mounted on the assembly and connected to the die for control of the die conduction.
Patent JP-4871122-B2 (JP)
IPC: G11B20/18
Filed: 2004-05-05
Granted: 2012-02-08
Abstract: A fast optimum power control method is disclosed, with a laser power level being adjusted in a predetermined sequence at an ADIP/ATIP frame of an optical recording medium. Jitter is measured at each ADIP/ATIP frame in order to obtain an average jitter value for that particular frame, and hence power level.
Patent JP-4851933-B2 (JP)
IPC: A61P3/06
Filed: 2004-04-09
Granted: 2012-01-11
Abstract: Novel 1,2,4-oxadiazole benzoic acid compounds, methods of using and pharmaceutical compositions comprising an 1,2,4-oxadiazole benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature translation termination or nonsense-mediated mRNA decay, or ameliorating one or more symptoms associated therewith.
Patent JP-4892341-B2 (JP)
IPC: B23K9/133
Filed: 2004-05-04
Granted: 2012-03-07
Abstract: The invention relates to a welding torch with a torch body and a drive unit, for supplying a welding wire, in particular, for differing wire feed speeds, or a forward/backward wire feed and a tube assembly, connected to the torch body at an angle to a mid axis of the welding torch, whereby a wire core, for the welding wire, or the welding wire itself follows a curved course to form a wire buffer store and the amount of the welding wire contained in the wire buffer store can be adjusted by changing the curved course. According to the invention, a welding torch may be produced which is as simple and compact in construction as possible with an improved dynamic property for the wire feed, whereby the wire buffer store is arranged directly after the region of the connection of the tube assembly within the torch body and the tube assembly is arranged at an angle of 33 to 90° to the mid axis of the welding torch.