baber/WOPTO huggingface dataset:
Patent CA-2990004-A1 (CA)
Inventor: MEKONNEN BELEW
IPC: A61K31/5513
Filed: 2016-06-17
Abstract: This invention relates to benzodiazepine derivatives, compositions comprising therapeutically effective amounts of those benzodiazepine derivatives and methods of using those derivatives or compositions in treating cognitive impairment associated with central nervous system (CNS) disorders. In particular, it relates to the use of a .alpha.5- containing GABA A receptor agonist (e.g., a .alpha.5-containing GABA A receptor positive allosteric modulator) as described herein in treating cognitive impairment associated with central nervous system (CNS) disorders in a subject in need or at risk thereof, including, without limitation, subjects having or at risk for age-related cognitive impairment, Mild Cognitive Impairment (MCI), amnestic MCI (aMCI), Age- Associated Memory Impairment (AAMI), Age Related Cognitive Decline (ARCD), dementia, Alzheimer s Disease(AD), prodromal AD, post traumatic stress disorder (PTSD), schizophrenia, bipolar disorder, amyotrophic lateral sclerosis (ALS), cancer-therapy-related cognitive impairment, mental retardation, Parkinson' s disease (PD), autism spectrum disorders, fragile X disorder, Rett syndrome, compulsive behavior, and substance addiction.
Patent CA-2990356-A1 (CA)
Inventor: DRILLET PASCAL
IPC: C21D8/02
Filed: 2016-06-10
Abstract: A press hardened steel part wherein the chemical composition of the steel comprises, in weight: 0.062% = C = 0.095%, 1.4% = Mn = 1.9%, 0.2% = Si = 0.5%, 0.020% = Al = 0.070%, 0.02% = Cr =0.1 %, wherein : 1.5% = (C+Mn+Si+Cr) = 2.7%, 0.040% = Nb = 0.060%, 3.4 x N = Ti = 8 x N wherein: 0.044% = (Nb + Ti) = 0,090%, 0.0005 = B = 0.004%, 0.001% = N = 0.009%, 0.0005% = S = 0.003%, 0.001% = P = 0.020%, optionally: 0.0001 % = Ca =0.003%, the remainder being Fe and unavoidable impurities, and wherein the microstructure comprises, in the majority of the part, in surface fractions: less than 40% of bainite, less than 5% of austenite, less than 5% of ferrite, the remainder being martensite, said martensite consisting of fresh martensite and of self- tempered martensite.
Patent CA-2990755-A1 (CA)
Title: Molecules bispecifiques de liaison a l'antigene activant les lymphocytes t anti-ceaxcd3
Inventor: BACAC MARINA
IPC: C07K16/30
Filed: 2016-09-29
Abstract: La présente invention concerne de manière générale de nouvelles molécules bispécifiques de liaison à l'antigène destinées à activer les lymphocytes T et à les rediriger vers des cellules cibles spécifiques. De plus, la présente invention concerne des polynucléotides codant pour ces molécules bispécifiques de liaison à l'antigène, ainsi que des vecteurs et des cellules hôtes comprenant ces polynucléotides. L'invention concerne par ailleurs des procédés de production des molécules bispécifiques de liaison à l'antigène de l'invention, et des procédés d'utilisation de ces molécules bispécifiques de liaison à l'antigène dans le traitement de maladies.
Patent CA-2991167-A1 (CA)
Inventor: JOSHI-HANGAL RAJASHREE
IPC: A61K31/70
Filed: 2016-07-01
Abstract: The invention provides a method of preparing a lyophilized pharmaceutical composition containing a compound described herein or a pharmaceutically-acceptable salt thereof. The process comprises dissolving the compound in a solvent comprising dimethylsulfoxide and optionally one or more co-solvents to form a solution, and then removing the solvent and any co-solvents by a freeze-drying process. Also provided by the invention are lyophilized pharmaceutical compositions and their use in medicine and in particular in the treatment of cancer.
Patent CA-2991808-A1 (CA)
Title: Unite de vibration d'oscillateur a bobine pour unite de travail ferroviaire
Inventor: SAMI REZA
IPC: E01B27/16
Filed: 2016-07-15
Abstract: Cette invention concerne un véhicule d'entretien de rails, comprenant un châssis, une unité de travail, et une unité de vibration. Le châssis comprend des roues qui se déplacent le long des rails. L'unité de vibration est accouplé à l'unité de travail et comprend un rotor, un stator, une première bobine de rotor couplée au rotor et une première bobine de stator couplée au stator.
Patent CA-2992975-A1 (CA)
Inventor: TSAI MINGLIANG LAWRENCE
IPC: A61F5/44
Filed: 2016-05-18
Abstract: A spring-loaded bag connector having a spring-loaded valve and a housing comprising a fluid inlet portion and a fluid outlet portion. The spring-loaded bag connector is configured to connect with a fluid collection bag to generate a self-closing collection bag. Additionally, the spring-loaded bag connector is configured to couple with a second coupling element, such as a coupling connector, to facilitate the drainage and collection of waste to a fluid collection bag. Uncoupling of the bag connector and the second coupling element results in minimal fluid contamination on the outer surfaces of the bag connector system. The bag connector systems provided herein are included in medical appliances for body waste management.
Patent CA-2993276-A1 (CA)
Inventor: ZHENG YONG
IPC: C07K16/28
Filed: 2016-08-11
Abstract: The present disclosure provides monoclonal antibodies against protein programmed cell death 1 (PD-1), which can block the binding of PD-1 ligands to PD-1, and therefore block the inhibitory function of PD-1 ligands on PD-1 expressing T cells. The antibodies of disclosure provide very potent agents for the treatment of multiple cancers via modulating human immune function.
Patent CA-2993761-A1 (CA)
Inventor: BEN AHARON RONI
IPC: G06F40/143
Filed: 2016-07-31
Abstract: A system implementable on a computing device having a processor and a memory, including a visual design system to generate a single visual data structure based on a hierarchy of components; a database to store at least one visual data structure and an associated signature where the signature represents at least a semantic composition of the at least one visual data structure; a signature comparer to match a signature of the single visual data structure to an associated signature of at least one visual data structure stored in the database and to present multiple versions of alternate visual data structures for the hierarchy of components for selection by a user; and where the alternate visual data structures are visually different and semantically similar to each other.
Patent CA-2996164-A1 (CA)
Inventor: PASSINI MARCO A
IPC: C12N15/11
Filed: 2016-08-26
Abstract: The present disclosure relates to modified antisense oligomers and related compositions and methods for increasing the expression of functional SMN protein and methods for treating spinal muscular atrophy and relates to inducing inclusion of exon 7 in SMN2 mRNA.
Patent CA-2999409-A1 (CA)
Inventor: YASUTOMI TAKASHI
IPC: B21D28/34
Filed: 2016-09-28
Abstract: This method for cutting using a press die involves using a punch to cut a workpiece comprising a first metal plate and a second metal plate joined by a weld, and having heat-affected zones around the weld. The punch comprises a flat section and a protruding section that protrudes further toward the workpiece than the flat section. The workpiece is positioned with respect to the punch at a position where the shearing of at least one of the weld and the heat-affected zones by the protruding section is to commence prior to the workpiece being cut by the flat section, and while in said position, the punch and die move relative to one another, shearing and cutting the workpiece across the weld.
Patent CA-3000543-A1 (CA)
Title: Procede de recuperation de zinc a partir d'une solution
Inventor: WELHAM NICHOLAS JAMES
IPC: C22B3/40
Filed: 2016-09-29
Abstract: La présente invention concerne un procédé de récupération de zinc à partir d'une solution ammoniacale aqueuse de zinc et de carbonate d'ammonium. Le procédé comprend les étapes consistant à : mettre la solution ammoniacale aqueuse de zinc et de carbonate d'ammonium en contact avec une solution organique d'un agent d'extraction de zinc de telle sorte qu'une partie du zinc est transférée à partir de la solution ammoniacale aqueuse de zinc et de carbonate d'ammonium, ce qui produit une solution ammoniacale aqueuse de carbonate d'ammonium appauvrie en zinc et une solution organique enrichie en zinc d'un agent d'extraction de zinc ; séparer la solution organique enrichie en zinc d'un agent d'extraction de zinc de la solution ammoniacale aqueuse de carbonate d'ammonium appauvrie en zinc ; mettre la solution organique enrichie en zinc en contact avec une solution acide aqueuse, ce qui produit une solution acide aqueuse enrichie en zinc et une solution organique appauvrie en zinc d'un agent d'extraction de zinc ; et récupérer du zinc à partir de la solution acide aqueuse enrichie en zinc.
Patent CA-3006480-A1 (CA)
Inventor: DEVRIES DOUGLAS EDWARD
IPC: B60K28/06
Filed: 2016-08-08
Abstract: A vehicle immobilization system includes a detection element operable to detect a level of an intoxicant in a user's breath. A control module is operable to receive a signal from the detection element indicating the level of intoxicant in the user's breath, and to selectively restrict operation of a vehicle based on the level of intoxicant in the user's breath exceeding a threshold by selectively sending a signal via a connection between the control module and the vehicle using a data link connection such as an Onboard Diagnostic (OBD) port of the vehicle.
Patent CA-3007179-A1 (CA)
Inventor: MAY ERIC J
IPC: C12Q1/26
Filed: 2011-12-28
Abstract: This disclosure relates to compositions that enhance the deposition of detectable moieties on tissue samples, methods utilizing these compositions and kits including these compositions. The compositions include a deposition enhancer having a formula and/or where R1, R2, R3, and R4 are independently selected from aliphatic, aryl, halogen, a heteroatom-containing moiety, and hydrogen; R1 and/or R3 can be bound to R2 to form a fused, aromatic ring system; R5 is selected from a heteroatom-containing moiety; A is selected from, a carbon atom, a heteroatom, other than sulfur, and any combination thereof; n is 1-5, an enzyme, a specific binding moiety and a detectable moiety.
Patent CA-3007664-A1 (CA)
Title: Structure arborescente a types multiples pour le codage video
Inventor: LI XIANG
IPC: H04N19/105
Filed: 2017-01-13
Abstract: L'invention concerne un procédé de décodage de données vidéo comprenant les étapes consistant à recevoir un flux binaire contenant une séquence de bits formant une représentation d'une image codée des données vidéo, partitionner l'image codée des données vidéo en une pluralité de blocs au moyen de trois structures de partition différentes ou plus, et reconstruire la pluralité de blocs de l'image codée des données vidéo. Le partitionnement de l'image codée des données vidéo peut consister à partitionner l'image codée des données vidéo en la pluralité de blocs au moyen desdites trois structures de partition différentes ou plus, au moins trois desdites trois structures de partition différentes ou plus pouvant être utilisées à chaque profondeur d'une structure arborescente qui représente la façon dont un bloc particulier de l'image codée des données vidéo est partitionné.
Patent CA-3007946-A1 (CA)
Title: Process for preparing sic-bonded polyethersiloxanes
Inventor: KNOTT WILFRIED
IPC: C08G77/46
Filed: 2018-06-12
Abstract: A process for preparing SiC-bonded polyethersiloxanes by precious metal-catalysed addition of olefinically unsaturated polyethers onto siloxanes having SiH groups is described, wherein, prior to commencement of reaction, the siloxane having SiH groups is mixed with an olefinically unsaturated polyether and with a polyethersiloxane by stirring, and then contacted with a precious metal catalyst and optionally further additives, and the SiC bond formation reaction is conducted up to an SiH  conversion, determined by gas-volumetric means, of at least 97%.
Patent CA-3010472-A1 (CA)
Title: Free air fire alarm cable
Inventor: HAZENFIELD ROBERT C
IPC: H01B7/295
Filed: 2017-11-09
Abstract: An electric wire includes a metal conductor, a heat stable tape, wherein the tape is in direct contact with the conductor, wherein the tape can withstand temperatures of at least about 1850°F  (1010°C), a high temperature fiberglass layer, wherein the fiberglass layer is in direct contact with the tape, and an insulating sheath around the fiberglass layer, wherein the wire has no conduit protection.
Patent CA-3012310-A1 (CA)
Title: User terminal, radio base station, and radio communication method
Inventor: TAKEDA KAZUKI
IPC: H04W48/08
Filed: 2017-01-26
Abstract: In order to realize proper communication in the next-generation communication system, a user terminal that performs communication through a communication system in which a plurality of communication parameters is set, includes: a reception section that receives information on a partial resource used for the communication; and a control section that controls UL transmission and/or DL reception using a predetermined communication parameter, based on the information on the partial resource. The reception section receives the information on the partial resource using higher layer signaling, a common control channel which is common to the plurality of communication parameters, or a specific control channel dedicated to each of the communication parameters.
Patent CA-3012774-A1 (CA)
Inventor: EVERY MARK ROBERT
IPC: H04R3/00
Filed: 2018-07-30
Abstract: A system and method receives one or more captured signals through a captured audio path and produces one or more playback signals through a playback audio path.  The system and method executes one or more signal processing functions and measures the delays within the playback audio path and captured audio path during operation of the one or more signal processing functions. The system and method stores the measured delays in a memory and compensates the one or more signal processing functions for the playback delay and the capture delay.
Patent CA-3013565-A1 (CA)
Title: Process for producing polyamide powders by precipitation
Inventor: ULZHOEFER ANGELA
IPC: C08L77/02
Filed: 2017-02-16
Abstract: The invention relates to a method for producing polyamide powders and the polyamide powder obtained according to said method. The invention also relates to the use of polyamide powder in the form of a sintered powder during selective laser sintering.
Patent CA-3014380-A1 (CA)
Inventor: KREKIAN SHARIS
IPC: B41J2/01
Filed: 2018-08-16
Abstract: A heat transfer sheet assembly and method is disclosed for improving the process of removing the carrier layer from a facestock layer. The heat transfer sheet assembly may include a heat transfer facestock layer and a carrier layer. The facestock layer may be attached to the carrier layer and include an indicia receptive surface along a side opposite the carrier layer. The carrier layer may include at least one peel line that extends from opposite edges of the assembly wherein the peel line assist to remove the carrier layer from the heat transfer facestock layer once indicia is printed on the facestock layer.
Patent CA-3017386-A1 (CA)
Inventor: FONSECA OCAMPOS ERNESTO RAFAEL
IPC: E21B34/14
Filed: 2017-03-15
Abstract: A method is provided to provide fractures in a subterranean formation that utilizes set of first wire line controllable valves (108) to open communication between the inside of a casing (107) and an outside of a casing that has been cemented into a wellbore (101). A wire line controllable valve associated with each of the first valves isolates the inside of the casing downstream of the first valve. The two valves are operated by a wire line actuator. After each successive fracture is formed, the wire line actuator is moved past the next set of valve, changing their positions, and then the next fracture is formed. The valve isolating the downstream portions of the casing are either opened, milled out, or made of degradable material after the operation is complete to enable production from the formation through the fractures into the well bore.
Patent CA-3018349-A1 (CA)
Inventor: GHESHLAGHI NADER
IPC: A01G9/20
Filed: 2018-09-21
Abstract: A hydroponics system and method for growing flowering and/or fruiting plants is disclosed that involves a periodic flood and drain system combined with periodic spraying or misting of the plants and appropriate lighting systems and oxygenation systems. Specific flooding, spraying, lighting and oxygenation times and apparatus are disclosed.
Patent CA-3022094-A1 (CA)
Inventor: CHELNIK MARC
IPC: G06F17/00
Filed: 2018-10-25
Abstract: Embodiments are described herein to identify matching users that share an affinity for particular subjects with a searching user. The embodiments may allow searching users to find and connect with matching users based on parameters, such as physical and/or virtual proximity of the users, one or more shared affinity subjects and/or privacy preferences associated with the users. The embodiments may provide notifications throughout the matching and connecting process and may allow connected users to manually and/or automatically share information with each other.
Patent CA-3024390-A1 (CA)
Inventor: WINKLE DAVID C
IPC: F25D3/10
Filed: 2017-05-18
Abstract: Selon certains modes de réalisation, l'invention concerne des systèmes et des procédés destinés à limiter le changement de température et/ou à réguler la température d'un produit pendant la livraison. Certains modes de réalisation concernent des systèmes destinés à limiter les changements de température, les systèmes comprenant : un système de refroidissement de produit comportant une cavité de produit destinée à porter un produit, le système de refroidissement de produit étant séparé et pouvant être retiré du véhicule de livraison et comprenant une isolation autour de la cavité de produit ; un système de distribution de substance cryogénique destiné à injecter une substance cryogénique dans la cavité de produit ; un capteur de température ; et un circuit de régulation de la température accouplé au capteur de température et au système de distribution de substance cryogénique, le circuit de régulation de la température étant conçu pour déterminer si une température du produit est supérieure à un seuil et pour activer de manière autonome le système de distribution de substance cryogénique afin de libérer la substance cryogénique.
Patent CA-3024611-A1 (CA)
Title: Vertical takeoff and landing aircraft with tilted-wing configurations
Inventor: LYASOFF RODIN
IPC: B64C3/38
Filed: 2017-02-16
Abstract: The present disclosure pertains to self-piloted, electric vertical takeoff and landing (VTOL) aircraft that are safe, low-noise, and cost-effective to operate for cargo-carrying and passenger-carrying applications over relatively long ranges. A VTOL aircraft has a tandem- wing configuration with one or more propellers mounted on each wing to provide propeller redundancy, allowing sufficient propulsion and control to be maintained in the event of a failure of any of the propellers or other flight control devices. The arrangement also allows the propellers to be electrically-powered, yet capable of providing sufficient thrust with a relatively low blade speed, which helps to reduce noise. In addition, each wing is designed to tilt, thereby rotating the propellers, as the aircraft transitions between forward flight and hover flight. While in the hover flight, the propellers may be offset from vertical so that horizontal thrust components of the propellers may be used to provide efficient yaw control.
Patent CA-3024874-A1 (CA)
Title: Systeme optique de mesure et de balayage et procedes d'utilisation
Inventor: KELLY JOHN
IPC: G06T17/00
Filed: 2017-05-26
Abstract: La présente invention concerne un système optique de mesure permettant d'ajuster des lunettes sur un sujet et/ou de diagnostiquer et/ou de suivre l'évolution de maladies et/ou de troubles oculaires chez le sujet, et des procédés d'utilisation associés. Le système comprend au moins un dispositif de capture d'image permettant de capturer au moins une image d'au moins une partie du visage du sujet. Le système comprend également au moins un support mobile destiné à monter le dispositif de capture d'image devant le sujet et à déplacer le dispositif de capture d'image par rapport au sujet ; et au moins un processeur connecté de manière fonctionnelle au dispositif de capture d'image pour générer un modèle tridimensionnel (3D) de la ou des parties du visage du sujet. Le ou les processeurs sont également configurés pour déterminer, à partir du modèle 3D généré, une ou plusieurs mesures optiques du sujet.
Patent CA-3024901-A1 (CA)
Title: Dispositif de surveillance de patient
Inventor: DOGRAMADZI SANJA
IPC: G06T7/20
Filed: 2017-05-19
Abstract: L'invention concerne un dispositif de détection de mouvement destiné à détecter quantitativement le mouvement d'un patient en capturant des images d'une surface déformable à laquelle est associé un indicateur, l'indicateur étant sensible aux changements d'un profil de la surface déformable. Les images capturées sont analysées pour en déduire un mouvement du patient à partir des changements du profil de la surface déformable. Par exemple, le dispositif de détection de mouvement de l'invention peut détecter le sens (translation et/ou rotation) et l'amplitude du mouvement du patient. Ces informations peuvent permettre un ajustement en temps réel du signal de traitement ou bien constituer un équipement de sécurité grâce auquel, s'il est détecté que le patient s'est déplacé ou s'est déplacé au-delà de certains paramètres, le dispositif qui est en train d'observer ou de traiter le patient est éteint.
Patent CA-3031331-A1 (CA)
Title: Cannabis products and industrial methods for production thereof
Inventor: SHADURIN YURI
IPC: A61K36/185
Filed: 2017-07-18
Abstract: Cannabis products and industrial methods for production thereof. A homogeneous composition comprising cannabinoid-containing comminuted cannabis plant material, where at least 70 weight% of the comminuted cannabis plant material is of a size greater than 0.3 millimeter and less than 4.2 millimeters; the composition comprises at least 1% by weight moisture and less than 20% by weight moisture; and the cannabinoid concentration in a 1 gram fraction of at least 10 gram sample of said homogeneous composition, is within 15% of the cannabinoid concentration in a separate 1 gram fraction of said 10 gram sample.
Patent CA-3032231-A1 (CA)
Inventor: RUKAT BRONISLAW
IPC: B21D51/26
Filed: 2017-07-03
Abstract: A can bodymaker comprising (201) a plurality of components that require relative alignment to one another. The can bodymaker (201) comprises a toolpack module (207) which includes a toolpack frame and components including one or more dies (501) supported by the toolpack frame. The die (501) are alignable with respect to the toolpack frame when the toolpack module is not attached to the bodymaker (201). The can bodymaker (201) further comprises a fixing that allows removable fixing of the toolpack module to the can bodymaker (201).
Patent CA-3032549-A1 (CA)
Inventor: CHUNG SHIN
IPC: A61K38/00
Filed: 2017-05-24
Abstract: L'invention concerne des dérivés d'acides nucléiques peptidiques ciblant le site d'épissage 5' de "l'exon 5" dans le pre-ARNm du récepteur des androgènes humains. Les dérivés d'acide nucléique peptidique induisent puissamment des variants d'épissage de l'ARNm du récepteur d'androgène dans des cellules, et sont utiles pour traiter en toute sécurité des indications ou des états dermatologiques impliquant une activité androgène lors de l'administration topique.
Patent CA-3033283-A1 (CA)
Inventor: RYAN ANDREW VINCENT
IPC: B63C13/00
Filed: 2017-06-13
Abstract: A boat is fitted with retractable wheels which can pivot between an extended land position and a retracted water position. A slot is formed in the hull of the boat. A housing sealing engages about the slot to prevent water entering the boat through the slot. The housing supports a pivot. An arm member is connected to the pivot and a wheel is connected to the arm member. The arm member can pivot through the slot between the wheel retracted and wheel extended positions.