baber/WOPTO huggingface dataset:
Patent CR-20190268-A (CR)
Inventor: GROEBKE-ZBINDEN KATRIN
IPC: C07D413/14
Filed: 2017-12-07
Abstract: La invención proporciona compuestos novedosos que tienen la fórmula general (I) en donde R1, R2, R3, R4, R5, R6, X, Y y Z es tal como se describe en el presente documento, composiciones que incluye los compuestos y métodos de uso de los compuestos.The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, X, Y and Z are as described herein, compositions including the compounds and methods of using the compounds.
Patent CR-20210523-A (CR)
Title: Substituted 2-azabicycles and their use as orexin receptor modulators
Inventor: SHIREMAN BROCK T
IPC: C07D519/00
Filed: 2014-03-12
Abstract: The present invention is directed to compounds of Formula I: wherein X is N or CR1; Y is N or CR2; R1 is H, alkoxy, halo, triazolyl, pyrimidinyl, oxazolyl, isoxazole, oxadiazolyl, or pyrazolyl; R2 is H, alkyl, alkoxy, or halo; Z is NH or O; R3 is H, alkyl, alkoxy, halo, or triazolyl; R4 is H or alkyl; or R3 and R4, together with the atoms to which they are attached, form a 6- membered aryl ring or a 5- or 6-membered heteroaryl ring; R5 is pyridyl, pyrazinyl, or pyrimidinyl, wherein the pyridyl, pyrazinyl, or pyrimidinyl is optionally substituted with halo or alkyl; and n is 1 or 2. Methods of making the compounds of Formula I are also described. The invention also relates to pharmaceutical compositions comprising compounds of Formula I. Methods of using the compounds of the invention are also within the scope of the invention.
Patent CR-20220420-A (CR)
Title: Herbicidal malonamides
Inventor: ZIMMERMANN GUNTHER
IPC: C07D309/08
Filed: 2021-02-17
Abstract: The invention relates to compounds of formula (I), and their use as herbicides. In said formula, R<sup>1</sup> to R<sup>9</sup> represent groups such as hydrogen, halogen or organic groups such as alkyl, alkenyl, alkynyl, or alkoxy; X is a bond or a divalent unit; Y is hydrogen, cyano, hydroxyl or a linear or cyclic organic group. The invention further refers to a composition comprising such compound and to the use thereof for controlling unwanted vegetation.
Patent EC-SP003701-A (EC)
Title: Derivados ii de quinolin-4-il
Inventor: BUETTELMANN BERND
IPC: C07D401/04
Filed: 2000-10-06
Abstract: El presente invento se refiere a compuestos de la fórmula General (gráfico), en donde R1 es hidrógeno, alquilo inferior, alcoxilo inferior, hidroxilo, amino, nitro, ciano, alquilo inferior-amino, di-alquil-amino inferior o halógeno; R2 es hidrógeno, alquilo inferior, amino, pirrolidin-3-ol, pirrolidin-2-il-metanol o -NHCH2CHROH; R3 es hidrógeno o halógeno; R es hidrogeno, alquilo inferior o -CH2OH; n es 1 o 2; y a sus sales de adición de ácido farmacéuticamente aceptables. Los compuestos del presente invento son bloqueadores selectivos de subtipos receptores del NMDA (N-metil-D-aspartato), que tienen una función clave en modualr actividad y plasticidad neuronal en procesos de inducción que son fundamentales en el desarrollo de CNS, asi como aprendimento y formación de la memoria.
Patent EC-SP034600-A (EC)
Title: Compuestos de lactama
Inventor: JOHN VARGHESE
IPC: C07K5/06
Filed: 2003-05-13
Abstract: La presente invención proporciona el compuesto (N)- (S)-2-hidroxi-3- metilbutiril)-1- (l-alaninil) -(S)- 1-amino-3-metil-4, 5, 6, 7- tetrahidro-2H-3-benzazepin-2-ona.
Patent EC-SP066282-A (EC)
Title: Proceso para la preparación de derivados de tetrazola partir de azidas de órgano-boro y de órgano-aluminio
Inventor: SEDELMEIER GOTTFRIED
IPC: C07D257/04
Filed: 2006-01-13
Abstract: La presente invención se refiere a un método para la preparación de tetrazoles sustituidos, a compuestos obtenidos de acuerdo con este método, a nuevos reactivos, y a nuevos derivados de tetrazol.
Patent EC-SP066401-A (EC)
Title: Interruptor de una paleta de balancín con accionamiento de leva semirigida
Inventor: ODDSEN DENNIS
IPC: H01H21/02
Filed: 2006-03-01
Abstract: Queda presentado un interruptor encendido - apagado que opera al empujar la porción inferior de una paleta de balancín para encender o apagar el interruptor. El borde inferior de la paleta de balancín gira hacia adentro o hacia fuera sobre su extremo superior. Los medios resorte de polarización fuerza a la porción inferior de la paleta de balancín a quedarse hacia fuera cuando el interruptor está en la posición de encendido o apagado. La paleta de balancín del interruptor no está colocada dentro de un marco y tiene, a lo largo de su eje vertical, una superficie de primer diferencial positivo y segundo diferencial cero, formado por una combinación de acanaladura que se extienden entre los puntos de distancias variables de un plano de información. La superficie tiene un segundo diferencial cero cuando el porcentaje de incremento de altura de las acanaladuras individuales es constante.Un accionamiento de leva semirígida unido a la paleta de balancín del interruptor ocasiona que la leva rote en el mismo sentido de las manecillas del reloj, cada vez que se presiona la paleta del balancín. La rotación alterna de la leva conduce a un miembro deslizante que tenga una leva a un movimiento de ida y vuelta a lo largo del eje linear. Un resorte plano o en láminas ayuda a la leva a seguir al movimiento del deslizante y a determinar sus otras posiciones. Se utiliza un indicador como el LED para determinar el estado de conducción del interruptor.
Patent EC-SP067067-A (EC)
Inventor: BRAIN CHRISTOPHER THOMAS
IPC: C07D401/04
Filed: 2006-12-07
Abstract: The present specification relates to the use of a quinazolinone compound of the formula (I) wherein R1, R2, R3, R4, R5 and m are as defined in the specification and in the claims, in free form or in salt form, and, where possible, in acid addition salt form.
Patent EC-SP077375-A (EC)
Inventor: HUCKBY DWIGHT R
IPC: B01F29/60
Filed: 2007-04-05
Abstract: An apparatus and method are provided for mixing paint disposed in either a conventional one gallon paint container or a square paint container having a body with a handle passage extending therethrough. The apparatus includes a square bucket for holding the container. A rocker is pivotably mounted to a side wall of the bucket and includes a pair of heads aligned over a pair of openings in the side wall. A floor of the bucket has a plurality of support structures extending upwardly therefrom. When the conventional one gallon paint container is disposed in the bucket, the container rests on the floor, the vertical axis of the container is offset from the central axis of the bucket, and both heads of the rocker are disposed against the container inside the bucket. When the square paint container is disposed in the bucket, the container is supported on top of the support structures so as to be elevated above the floor, the vertical axis of the container is collinear with the central axis of the bucket, and one of the heads of the rocker is disposed in the handle passage of the container.
Patent EC-SP077812-A (EC)
Title: Sales de mono-lisina de compuestos de azol
Inventor: GAO QI
IPC: A61K31/04
Filed: 2007-10-16
Abstract: Se proporcionan sales de mono-lisina de compuestos de triazol que tienen un grupo hidroxi secundario o terciario. De modo más particular, se proporcionan los nuevos compuestos de sal de mono-lisina antifúngicos de triazol solubles en agua, o solvatos de los mismos, que tienen la fórmula general I: en donde A en la fórmula I representa la porción distinta de hidroxi de un compuesto antifúngico de triazol del tipo que contiene un grupo hidroxilo secundario o terciario. R y R1 en la fórmula I pueden ser cada uno un átomo de hidrógeno o un grupo alquilo que tiene uno a seis átomos de carbono. Los nuevos compuestos de azol solubles en agua son útiles para el tratamiento de infecciones fúngicas y pueden administrarse por vía oral, tópica y parenteral.
Patent EC-SP088661-A (EC)
Title: Un método para usar un micronutriente como asegurador para un triazol para controlar hongos nocivos
Inventor: FINCH CHARLES W
IPC: C05G3/60
Filed: 2008-08-04
Abstract: Un método para usar un micronutriente seleccionado del grupo que comprende sales y aductos de Mg, Ca, B, Mn, Fe, Co y Zn y Mo como asegurador para un triazol, seleccionado del grupo que comprende azaconazol, bitertanol, bromuconazol, ciproconazol , difenoconazol, diniconazol, enilconazol, epoxiconazol, fenbuconazol, fluquinconazol, flusilazol, flutriafol, hexaconazol, imibenconazol, ipconazol, metconazol, miclobutanilo, penconazol, propiconazol, protioconazol, simeconazol, tebuconazol, tetraconazol, triadimenol, triadimefona y triticonazol o sales o aductos de los mismos para controlar hongos nocivos.
Patent EC-SP972328-A (EC)
Title: Derivados de la 4-hidroxi -piperidina
Inventor: PINARD EMMANUEL
IPC: A61K31/14
Filed: 1997-12-03
Abstract: El invento se refiere a un compuesto de fórmula I (gráfico), en donde X significa -o-, NH-, -CH2-, -CH=, -CHOH-, -CO-, -S-, -SO-, ó -SO2-; R1-R4 son independientemente la una con respecto a la otra, hidrógeno, hidroxi, alquilo inferior-sufonilamino, 1 ó 2 -imidazoílo o acetamido; R5-R8 son independientemente la una con respecto a la otra, hidrógeno, hidroxi, alquilo inferior, halógeno, alcoxi inferior, trifluormetido o trifluormetiloxi; a y b pueden ser un enlace doble, con la condición de que, cuando "a" sea una enlace doble, "b" no puede ser un enlace doble; n es 0-2; m es 1-3; p es 0 ó 1 y a sales de ésta, aceptable desde el punto de vista farmacéutico. Los compuestos de la presente invención, son bloqueantes selectivos del subtipo receptor de NMDA (N-metil-D-aspartato), los cuales se pueden utilizar en procesos mediadores subordinados al desarrollo de la CNS, incluyendo la función del aprendisaje y formación de memoria.
Patent EC-SP982505-A (EC)
Title: Una nueva sal
Inventor: BRODIE ALASTAIR COUPER
Filed: 1998-05-14
Abstract: La presente invención describe la sal de hemisulfato del (1s, 4r)-cis-4-[2-amino-6-(cicloporilamino)-9H-purin-9-il]-2-ciclopenten-1-metanool o un solvato del mismo. También se describen rutas de preparación y compuestos de partida para fabricar la sal de hemisulfato. La sal de hemisulfato es útil en medicina, particularmente en el tratamiento de infecciones virales.
Patent EC-SP982678-A (EC)
Title: Derivados de resorcinol
Inventor: HU LAN
IPC: A61K31/04
Filed: 1998-09-23
Abstract: La presente invención se refiere al uso de ciertos derivados de resorcinol como agentes clarificadores de la piel.
Patent FI-19991702-A (FI)
Inventor: ASIKAINEN PENTTI
IPC: G08G1/017
Filed: 1999-08-11
Abstract: The invention relates to a communication method and an arrangement for communicating vehicular driving data. More specifically, the invention relates to a communication method and an arrangement for communicating vehicular weight measurements and other driving data. The present inventive method and arrangement enables the transfer of weighing data from a weighing system to an on-board computer without stops. A document regarding the weighing may be composed in the weighing system or in the on-board computer. The invention is preferably applicable to vehicular control weighings as well as to commercial weighings e.g. within factory areas, in road traffic, and in railway yards.  <IMAGE>
Patent FI-20055078-A (FI)
Inventor: ALA-LUUKKO SAMI
IPC: H04L29/06
Filed: 2005-02-18
Abstract: In order to facilitate the maintaining of associations re- quired in inter-domain communications, preferably name (41-1) and address information (41-2) on domains and in- formation on interworking agreements (41-3) between dif- ferent domains is maintained in a reliable network external to said domains. A network node (41) via which inter- domain traffic is routed is arranged to use said maintained information when checking whether or not a sender of a message is the one the sender claims to be and preferably also whether or not an agreement exists between the sender's domain and a receiver's domain. Provided that the sender is the claimed one, the message is forwarded, preferably to an address maintained for the receiver's do- main.
Patent FR-1602621-A (FR)
Title: Prophylactic dental paste compsns - comprising zirconium silicate and tin dioxide
IPC: A61K8/28
Filed: 1966-05-16
Granted: 1971-01-04
Abstract: Prophylactic dental paste compositions comprising zirconium silicate (ZrSiO4) and tin dioxide (SnO2). The new compositions are efficient for cleaning and polishing teeth while reducing hard tooth structure loss due to abrasion. A composition is prepared containing ZrSiO4 (50-99%, pref. 75-92.5% by wt.) and the balance of SnO2. A 9:1 wt. ratio of ZrSiO4 to SnO2 is preferred. The ZrSiO4 particles are distributed throughout three levels, namely 10-50% of particles up to about 20 microns (pref. 10-20 microns), 5-25% of particles of 50-75 microns and the residue of particles of 20-50 microns in size.
Patent GB-1045673-A (GB)
IPC: B23Q16/06
Abstract: 1,045,673. Indexing. MIDDLESEX TOOL & GAUGE CO. Ltd. July 23, 1963 [April 27, 1962], No. 16181/62. Heading B3B. An indexing assembly comprises a table 39 rotated by a fluid motor, a pawl 96 engaging notches in a disc 89 coaxial with the table, and means 105 for reversing the motor when the pawl enters a notch to hold the pawl and disc in an indexed position. The notches may be regularly or irregularly spaced and one or more notches may be blanked off by a plate 148. When a manual valve is operated, the table motor is started and air is also supplied to a groove 66 to lift the table and assist rotation. The pawl plunger 96 is forced out of its notch against a spring 98, thus depressing a plunger 102 and actuating a valve 105. This sets a circuit so that, when the pawl drops into the next notch, release of the valve 105 causes reversal of the motor and a firm holding of the table against the pawl. The continued pressure supply to the motor tends to force apart clutch members 51, 52, causing a clamping movement to be exerted on the table as springs 32, 56 yield. The pressure may cause automatic commencement of a machining operation. Lifting lugs are provided.
Patent GB-1051882-A (GB)
IPC: E01D19/06
Abstract: 1,051,882. Expansion joints. KINS DEVELOPMENTS Ltd. Feb. 11, 1964 [Feb. 19, 1963], No. 39270/65. Divided out of 1,051,881. Heading E1G. A flexible insert has a flat surface 28 and a non-planar surface 50, reinforced with a flexible material 51, 52 secured to the sides of the gap 21, such that the surface 28 remains substantially flat during variations in the gap width. The surface 50 is preferably part cylindrical with its centre in the flat surface at the mean compression. The reinforcement is rolled to provide anchorage for the insert. The inserts may be used in series for larger gaps.
Patent GB-1052050-A (GB)
IPC: F04B53/14
Abstract: 1,052,050. Reciprocating pumps. RESEARCH & DEVELOPMENT PTY. Ltd. April 21, 1965 [May 6, 1964], No. 16691/65. Heading F1A. A pump, e. g. for corrosive liquid or slurry, comprises a cylinder 2 with a piston 1 defining a pumping chamber 4 connected to inlet and delivery valves 16, 17 and an actuating chamber 3 connected alternately to sources of high and low pressure liquid by a control valve unit 22. As shown, high pressure liquid is supplied by centrifugal pump 28 to effect the delivery stroke of piston 1, the return stroke being effected by the inlet pressure of the pumped liquid which returns the actuating liquid to reservoir 29. Valve unit 22 is driven by a drive unit 23. In another embodiment, actuating chamber 3 is connected to a reciprocating piston which effects reciprocation of piston 1 through a liquid column. The specific weight of piston 1 may be made such that it floats in the actuating liquid permitting leakage of actuating liquid into the pumped liquid. Piston 1 engages a seal 7 to close the actuating chamber inlet 8 at the top of its stroke. A seal also may be provided at the pumping chamber inlet 10. Several pumps may be operated out of phase to deliver into a common delivery line.
Patent GB-1052624-A (GB)
IPC: B61B13/12
Abstract: 1,052,624. Electrical speed regulating of rail trucks. SIEMAG MASCHINENUND STAHLBAU NETPHEN G.m.b.H. June 21, 1963 [June 22, 1962], No. 24710/63. Heading B7L. Electrical speed regulating apparatus for rail trucks 2 comprises an electric motor 9 pivoted at 10 to support block 7 and biased by spring 11 to engage a friction pulley 16 on shaft 12 with a passing truck to accelerate or brake the truck depending on the speed and direction of rotation of motor 9. The pulley 15 comprises a friction ring 20 surrounding pulley 15 with a clearance and held on the pulley by removable plates 17, 18. A support roller 6 prevents a truck from toppling when engaged by pulley 15, 20. The motor 9 has, in every obtainable torque range, a maximum torque at or about zero revolutions and can also be stalled whilst current is flowing. In Fig. 6, not shown, the pulley is driven through a reduction gearing and spring 11 is replaced by a piston cylinder pressurized by a pump device actuated by a passing truck. In operation, a truck closes a contact 25, Figs. 1, 7, not shown, to energize a time relay 28, a second contact 26 being positioned behind the contact 25 so that relay 28 is still energized to close a switch 28a when contact 26 is closed if the truck is exceeding a predetermined speed. When this happens a contactor 29 is energized to close contacts 30 to drive motor 9 counter to the direction of truck travel to brake the truck; a centrifugal switch reverses the motor when a predetermined speed has been reached. If the truck is not exceeding the predetermined speed then, relay 28 opens switch 28a, as shown, before contact 26 is operated to energize contactor 31 to close contacts 32 to drive motor 9 in the direction of travel of the truck to accelerate the truck; self-holding contacts 33, 34 keep contactors 29, 31 energized until a contact 35 is depressed by a truck leaving the regulating apparatus. Several pulleys may be driven from the same motor. A weight-detecting apparatus may set the motor 9 for one of three different torque ranges depending on the weight of the truck.
Patent GB-1054332-A (GB)
IPC: B22D11/128
Abstract: 1,054,332. Continuous casting-machines. A. WERTLI. May 21, 1964 [May 25, 1963], No. 21043/64. Heading B3F. In a method of horizontal continuous casting the die 1 is stationary and the casting 4 is withdrawn a pre-determined distance and then moved back a slightly less distance. The casting 4 is withdrawn by longitudinal movement of grippers 15, clamping jaws 9 moving therewith to load a spring 13 until a stop 14 is engaged whereafter the casting slides through the jaws 9 until the stroke of the grippers 15 is completed. The grippers 15 then release the casting and the spring forces it and the clamping jaws 9 back towards the die, the grippers 15 being returned to their initial position for the next withdrawal stroke.
Patent GB-1054885-A (GB)
IPC: C22C1/02
Abstract: 1,054,885. Treating molten metal. KAISER INDUSTRIES CORPORATION. June 4, 1965 [June 8, 1964], No. 23949/65. Heading C7D. Molten metal is treated with volatile treating material, e. g. molten steel is deoxidized or desulphurized with Ca or Mg or A1 alloys thereof, by maintaining it in a vessel 40 having a liquid holding portion and an enclosed vapour space in which is maintained a passive gas such as He supplied through line 61, and a sufficient quantity of the volatile treating material, e. g. introduced from a bin 50 via valves 51 and air-lock 52, the walls of the vapour space being maintained above the freezing point of the treating material, and a condensing surface, e.g. condenser 53 fed with coolant through line 55, contained in the vapour space being maintained between the melting and boiling points of the treating material. The vapour space may be enclosed by the upper part of the vessel itself Fig. 1, (not shown) or by an open-bottomed bell 42 within the vessel dome 41 (see Fig. 2), the refractory rim 43 of the bell being immersed in the molten metal 45. As shown, the walls of the bell 42 and conduit 48 connected thereto contain heating elements 65, and the metal is stored and heated by induction heaters 57. The vapour space is preferably maintained to superatmospheric pressure. Floating insoluble material 66 may be removed by a rake 67 into a separate chamber 68.
Patent GB-1134979-A (GB)
Abstract: 1,134,979. Knitting. M. PHILIP. 18 Oct., 1967 [25 Nov., 1966], No. 47440/67. Heading D1K. An insulating fabric is produced on a rib machine in which succeeding sections are knitted of a 2 x 2 or more rib structure the plain and rib loops being in reverse order in the succeeding sections as shown in Fig. 1. The rib structure may be further enhanced by incorporating half or full cardigan stitch within it or any other rib, tuck or welt stitch arrangement. The fabric may be produced on a cylinder and dial machine as described in Specifications 914,585 and 1,045,583 in which the positional variation of the rib and plain wales is achieved by flexing the dial needles.
Patent GB-1143620-A (GB)
IPC: A47G29/126
Abstract: 1,143,620. Letter plates. E. HOLDEN & CO. (B'HAM) Ltd. 6 Oct., 1967 [2 Dec., 1966], No. 54094/66. Heading A4T. A letter plate closure flap 12 hinges at 13 and closes under gravity and has a portion 15 of magnetic material whereby the flap is held closed by magnet 14 on the plate to prevent rattling.
Patent GB-1227635-A (GB)
IPC: F16D21/00
Filed: 1969-09-23
Abstract: 1,227,635. Gearing for stopping and starting machinery. SPERRY RAND CORP. 23 Sept., 1969 [26 Sept., 1968], No. 46715/69. Heading F2L. A drive mechanism for an aircraft throttle control comprises a power-driven input shaft 14 carrying a sun gear 13 which meshes planet pinions 10 carried by an output drum 23 and the planet pinion are normally held against rotation by oppositely directed ratchet mechanism 17, 24; 18, 26 to lock the planet train and thus provide a drive from the shaft 14 to the drum 23. On initial rotation of a manually rotatable input drum 33 the ratchet mechanisms are disengaged to disconnect the shaft 14 from the drum 23 and thereafter the input drum 33 drives the output drum 23 directly. The input drum 33 carries adjustable stops 37, 38 which on initial rotation of the drum 33 engage pins 34, 36, 41, 46 fast with pawls 24, 26 to tilt the latter out of engagement with their associated ratchet wheels 17, 18 fast with the planet pinion 10. The pawls which prevent rotation of the planet pinions are arranged to engage different points on the teeth of their respective ratchet wheels to reduce lost motion in the drive mechanism.
Patent GB-1228400-A (GB)
IPC: H01H3/00
Filed: 1968-12-13
Abstract: 1,228,400. Fluid-pressure actuated switches. CONTROLS CO. OF AMERICA. 14 Nov., 1969 [13 Dec., 1968], No. 59540/68. Heading H1N. In a fluid-pressure actuated switch operated by a diaphragm 18 to move a spring tongue 13 against the action of a spring 16 whereby the tongue 13 and coil spring 14 move over-centre to operate the contact blade 12, further movement of the tongue 13 on over-pressure moves a second contact arm 15, between fixed contacts 27, 29 and operates as a safety cut-off switch. The arm 15, may have a limited lostmotion before engagement with a return spring assembly 22, 23. A bridge 17 on the diaphragm 18 may operate an additional set of contacts (not shown).