baber/WOPTO huggingface dataset:
Patent AU-765170-B2 (AU)
Title: Full term development of animals from enucleated oocytes reconstituted with adult somatic cell nuclei
Inventor: WAKAYAMA TERUHIKO
IPC: C12N5/10
Filed: 1999-01-20
Granted: 2003-09-11
Abstract: Animals are produced following injection of adult somatic cell nuclei into enucleated oocytes. The invention provides a method for cloning an animal by directly inserting at least a portion of the adult somatic nucleus (including the minimum chromosomal material able to support development) into a recipient enucleated oocyte. Preferably, the nucleus is inserted by microinjection and, more preferably, by piezo electrically-actuated microinjection. The oocyte is activated prior to, during, or up to about 6 hours after insertion of the nucleus, by electroactivation or exposure to a chemical activating agent, such as Sr2+. The activated renucleated oocyte is allowed to develop into an embryo and is transplanted to a host surrogate mother to develop into a live offspring.
Patent AU-610269-B2 (AU)
Title: Heterocyclically substituted n-sultamsulfonamides, process for their preparation and their use as herbicides and plant growth regulators
Inventor: WILLMS LOTHAR
IPC: A01N47/36
Filed: 1988-10-28
Granted: 1991-05-16
Abstract: Compounds of the formula I or their salts   <IMAGE> (I)  wherein R1 and R2 denote H, halogen, alkyl, alkenyl, alkynyl or alkoxy, which can be substituted, or denote -(CH2)n-COOR11; R3 denotes H, alkyl, alkenyl or alkynyl; R4 denotes a heterocyclic radical of the formulae <IMAGE>   where E is CH or N; X is O or S nd a, b, c, d, e in each case denote 0, 1 or 2, with the proviso that c+d+e>/=2, possess excellent herbicidal and plant growth-regulating properties.
Patent AU-700924-B2 (AU)
Title: Process for converting 2,4-dichloropyridines into 2-aryloxy-4-chloropy ridines
Inventor: CHEN YUHPYNG L
IPC: B01J27/122
Filed: 1995-06-06
Granted: 1999-01-14
Abstract: This invention relates to a process for converting 2,4-dichloropyridines into 2-aryloxy-4-chloropyridines, comprising reacting a compound of formula (I), wherein R1 is (C1-C4)alkyl; R2 is methyl or ethyl; and R3, R4 and R5 are selected, independently, from (C1-C4)alkyl and (C1-C4)alkoxy; or a pharmaceutically acceptable salt thereof; comprising reacting a compound of formula (II), wherein R1 and R2 are defined as above, with a compound of formula (III), wherein R3, R4 and R5 are defined as above, in the presence of a base that is capable of deprotonating the compound of formula (III), optionally in the presence of an organometallic halide or oxide and a suitable solvent, and then optionally converting the resulting compound of formula (I) into a pharmaceutically acceptable salt of such compound.
Patent AU-742241-B2 (AU)
Title: PNA and DNA conjugates and methods for preparation thereof
Inventor: COULL JAMES
IPC: C07F9/24
Filed: 1999-02-10
Granted: 2001-12-20
Abstract: Disclosed herein are methods for linking a protein or other biomolecule containing a carboxylic acid moiety to a PNA or DNA probe molecule. The methods disclosed herein involve activating the carboxylic acid moiety with an activating agent and reacting the activated carboxylic acid moiety with a PNA or DNA probe having an arylamine or aminooxyacetyl moiety. Conjugates produced by these methods are also disclosed.
Patent AU-664058-B2 (AU)
Title: New cephalosporins containing in position 7 a substituted benzyloxyimino radical, their preparation process and their use as medicaments
Inventor: ASZODI JOZSEF
IPC: C07D501/24
Filed: 1992-12-14
Granted: 1995-11-02
Abstract: New intermediates (III) - (VI) and (VIII) for the preparation of cephalosporins, comprising a substituted benzyloxyimino group in position 7, are new.  New intermediates of formulas (III) - (VI) and (VIII) for the preparation of cephalosporins, comprising a substituted benzyloxyimino group in position 7, are new.  R1p-R5p = R1-R5 or protected group;  R1-R3, R5 = H, halo, OH, 1-4C alkyl (optionally substituted with at least one halo), 1-4C alkoxy, mercapto, 1-4C alkylthio, nitro, cyano, amino (optionally substituted with one 1-4C alkyl), 2-8C dialkylamino, carbamoyl, 2-5C alkylamino-carbonyl, 3-9C dialkylamino-carbonyl, 2-5C alkoxycarbonyl, 1-8C acyloxy or SO2-N(Rx)(Ry);  Rx, Ry = H or 1-4C alkyl;  R4 = OH or 1-8C acyloxy;  R7 = ester residue;  R8 = H or protecting group; and provided R3 and R5 are the same as R4 when:  (1) R1, R2 or R3, or R2, R4 or R5 is F, Br, I or cyano; or  (2) R1 and R5 are both other than H; or  (3) R2 and R5 are both Cl.
Patent AU-658261-B2 (AU)
Title: Amino-substituted benzoylguanidines, process for their preparation, their use as a medicament and medicament containing them
Inventor: ENGLERT HEINRICH
IPC: C07D295/14
Filed: 1993-02-12
Granted: 1995-04-06
Abstract: There are described benzoylguanidines of the formula I <IMAGE> in which R(1) or R(2) is an amino group -NR(3)R(4), where R(3) and R(4) are equal to H, (cyclo)alkyl or R(3) is equal to phenyl-(CH2)p- where p = 0, 1, 2, 3 or 4, or phenyl, or R(3) and R(4) together can also be a methylene chain, and in which the other substituent R(1) or R(2) in each case is H, F, Cl, alkyl, alkoxy, CF3, CmF2m+1-CH2-, benzyl or phenoxy, and their pharmaceutically tolerable salts. The compounds according to the invention have very good antiarrhythmic properties, such as they show, for example, in the case of oxygen deficiency symptoms. The compounds are used as antiarrhythmic medicaments having a cardioprotective component for infarct prophylaxis and infarct treatment and also for the treatment of angina pectoris, where they preventively inhibit or strongly decrease the pathophysiological processes during the formation of ischaemically induced damage, in particular during the induction of ischaemically induced cardiac arrhythmias.
Patent AU-569555-B2 (AU)
Title: Preparing urea
Inventor: JONCKERS KEES
IPC: C07C273/04
Filed: 1984-11-12
Granted: 1988-02-04
Abstract: Process for preparing urea in which,
 in a synthesis zone, at a pressure of 125-350 bar and at the temperature belonging thereto, a urea synthesis solution containing carbamate and free ammonia is formed from carbon dioxide and an excess of ammonia,
 in a first decomposition step, at synthesis pressure or lower, a part of the carbamate is decomposed by supply of heat and the gas phase obtained in this process is condensed in a first condensition zone,
 in a second decomposition step, at a pressure of 4-40 bar, a further part of the carbamate still present is decomposed by supply of heat and the gas phase formed is separated off,
 in a further step, the remaining carbamate is removed in the form of a gas mixture containing ammonia and carbon dioxide, and this gas mixture is processed to form a solution of ammonia and carbon dioxide in water,
 and the remaining urea-containing solution is processed to form a concentrated urea solution. 
<??>The urea solution to be concentrated is introduced into the tubes of a shell and tube heat exchanger, the gas mixture from the second decomposition step is led into the shell side of heat exchanger at the end opposite the place where the urea solution to be concentrated is fed, the solution of ammonia and carbon dioxide in water is fed to the said shell side at a place located between the inlet for the gas mixture and the inlet for the urea solution to be concentrated, and the condensate is discharged from the shell side at the end where the urea solution is led into the tubes.
Patent AU-671827-B2 (AU)
Title: Calanolide antiviral compounds, compositions and uses thereof
Inventor: BOYD MICHAEL R
IPC: C07D493/14
Filed: 1993-03-24
Granted: 1996-09-12
Abstract: The present invention provides novel antiviral compounds, refered to as calanolides, and their derivatives of formulae (I) and (II) which may be isolated from plants of the genus Calophyllum in accordance with the present inventive method. The compounds and their derivatives may be used alone or in combination with other antiviral agents in compositions, such as pharmaceutical compositions, to inhibit the growth or replication of a virus, such as a retrovirus, in particular a human immunodeficiency virus, specifically HIV-1 or HIV-2.
Patent AU-675219-B2 (AU)
Title: Method for manufacturing self-supporting synthetic trim parts and thus manufactured trim parts
Inventor: LUCIEN JOURQUIN
IPC: B60R7/04
Filed: 1993-05-18
Granted: 1997-01-30
Abstract: PCT No. PCT/BE93/00026 Sec. 371 Date Jan. 19, 1995 Sec. 102(e) Date Jan. 19, 1995 PCT Filed May 19, 1993 PCT Pub. No. WO93/23237 PCT Pub. Date Nov. 25, 1993In the method according to the invention, a layer of polyurethane elastomer for obtaining a polyurethane skin (5) is produced, in a first step, against a mould surface (1). In a second step, a reaction mixture for obtaining a polyurethane foam layer (6) is applied against this polyurethane skin (5). In a third step, a suitable polyurethane or polyisocyanurate reaction mixture for obtaining a rigid synthetic carrier (8) is applied against the polyurethane foam layer (6). In this way, a synthetic trim part is obtained which is easier to recycle. This method can moreover also be performed easier.
Patent AU-669523-B2 (AU)
Title: Coin-deposit lock
Inventor: LENANDER AAGE
IPC: G07F7/06
Filed: 1993-04-28
Granted: 1996-06-13
Abstract: PCT No. PCT/DK93/00141 Sec. 371 Date Oct. 13, 1994 Sec. 102(e) Date Oct. 13, 1994 PCT Filed Apr. 28, 1993 PCT Pub. No. WO93/22750 PCT Pub. Date Nov. 11, 1993.A coin-deposit lock to be placed on a trolley being part of a row of mutually connected e.g. shopping trolleys or baggage trolleys comprises a main slide being longitudinally slidable against the force from a spring and a measuring slide likewise longitudinally slidable against the force from a second spring. Each of the slides has a transverse central aperture, and when a coin of a certain value (diameter) has been inserted between the slides, the apertures are mutually aligned. Upon insertion of a key belonging to the lock in a first key opening in the lock, the slides can be moved to a position in which a latching finger on a pivotable release member engages in the mutually aligned apertures and retains the slides and the coin between them in a withdrawn position. At the same time, the release member pivots to a position, in which a second latching finger on it frees a second key associated with a previous trolley in the row thus freeing the trolley from the row.
Patent AU-690411-B2 (AU)
Title: One-piece laser/ink jet printable divider
Inventor: OWEN SONIA
IPC: B42F21/00
Filed: 1995-11-30
Granted: 1998-04-23
Abstract: A one-piece divider assembly which is folded over along one edge may be fed into a laser printer, ink jet printer, or photocopier. The assembly includes a divider sheet having a binding edge, a reduced-thickness binding edge region extending inwardly from the binding edge, and a main body with an integral, outwardly-extending tab. The divider sheet has a folding line which is inset from and which runs parallel to the binding edge. The binding edge region has a folding portion defined on one side by the binding edge and on the opposite side by the folding line. The binding edge region also has a non-folding portion adjacent to the folding portion. The folding portion includes spaced holes for a binder. A binding edge reinforcement film may be adhered to at least a portion of the binding edge region. The folding portion of the binding edge region may be folded over at the folding line, and the folding portion may be releasably tacked with a single-use adhesive to the non-folding portion of the divider sheet. In an alternative embodiment, the main body may have an upper sheet and a lower sheet that are adhered to one another.
Patent AU-750696-B2 (AU)
Title: Use of a cationic polymer for the preparation of a complex with nucleic acid and related compositions
Inventor: KOLBE HANNO V J
IPC: A61K47/48
Filed: 1999-08-25
Granted: 2002-07-25
Abstract: The present invention discloses complexes comprising     a) at least one polymer of the general formula : <CHEM>  wherein:     the degree of polymerization p ranges from 2 to 1000000, R1, R2 and R3, independently of one another in each ÄCH - CH2Ü repeat, are selected from H, alkyl of to 20 carbon atoms or aryl of 5 to 7 carbon atoms, n is 0 or 1, with the proviso that at least one n is 1 in the full length of the polymer, and     b) at least one nucleic acid.   Further disclosed are pharmaceutical compositions comprising these complexes which can be used for intra cellular delivery of nucleic acids.
Patent AU-728409-B2 (AU)
Title: Shear separation method and system
Inventor: BRANTLEY JOHN D
IPC: A23J1/20
Filed: 1997-09-05
Granted: 2001-01-11
Abstract: A shear separation system or method uses shear lift forces and permeate drag forces to separate substances having a size less than a predetermined separation size from substances having a size greater than the separation size. The balance of the drag forces and lift forces affects a predetermined separation size in that the balance of forces reads the transmembrane passage of substances larger than the separation size yet allows substances smaller than the separation size to pass through the permeable membrane. The shear separation device, method and system can be employed to separate or concentrate from a process fluid substances larger or smaller than the predetermined separation size.
Patent AU-707049-B2 (AU)
Title: Galvanic/sorptive Reaction Cell and Method
Inventor: VINZ PETER
IPC: H01M8/18
Filed: 1996-02-06
Granted: 1999-07-01
Abstract: The invention relates to a galvanosorptive reaction cell with closed substance circulation for the conversion of low temperature heat, preferably of waste heat into useful electrical work. The reaction cell and the accompanying isobaric substance circuit are presented. The galvanosorptive reaction process inside the cell is carried out polytropically with an electrostatic auxiliary voltage, which is superimposed onto the inherent voltage of the cell. In this way, not only free but, with cooling of the reaction system, also substance-bound reaction work can be extracted from the reaction system. The electrical energy yield and the power density of galvanosorptive reaction cell are thereby increased many times over.
Patent AU-565805-B2 (AU)
Title: Steel tension rod production and the product thereby
Inventor: AICHER MAX
IPC: E04C5/03
Filed: 1985-08-23
Granted: 1987-10-01
Abstract: To produce threaded steel tension members, steel is used with a C-content of 0.50 to 0.80%, preferably 0.75%, a Si-content of 0.20 to 0.50%, preferably 0.25%, and a Mn content of 0.30 to 0.80%, preferably 0.60%. Exiting from the rolling heat at the outlet side of the finishing stand after hot rolling, the tension member or rod is subjected to surface quenching by a cooling medium, preferably water, so that the steel in a rim zone R1 is transformed immediately and completely into martensite, while the heat content remaining in the core zone K1 does not effect a tempering of the martensite rim zone during the subsequent cooling beyond the range of the intermediate stage. Steel tension members of this type have a high ductility and toughness at a high yield limit and high strength, they are corrosion-resistant to a great degree and have a wear resistant surface which makes them particularly suitable for threaded tension rods in which the threads are produced either by a cold forming operation or hot rolled ribs.
Patent AU-579443-B2 (AU)
Title: New cationic surfactants based on quaternary ammonium compounds and use thereof in cleaning agents
Inventor: GEKE JURGEN DR
IPC: C07C215/40
Filed: 1986-01-20
Granted: 1988-11-24
Abstract: The invention relates to new cationic surfactants based on quaternary ammonium compounds corresponding to the general formula R1-CHOH-CHR2-N+R3R4R5 R6CO2-(1) wherein R1 is a linear or branched alkyl residue having from 1 to 22 carbon atoms; R2 is hydrogen or a linear or branched alkyl residue having from 1 to 21 carbon atoms, the total number of carbon atoms of the substituents R1 and R2 being in the range of from 8 to 22; R3 and R4 each represent methyl, ethyl, 2-hydroxyethyl or 2-hydroxypropyl; R5 represents an alkyl residue having from 4 to 6 carbon atoms or a phenalkyl residue having from 1 to 3 carbon atoms in the alkyl residue; and R6 represents a linear or branched alkyl residue having from 4 to 15 carbon atoms. The cationic surfactants have particular utility in cleaning agents.
Patent AU-668249-B2 (AU)
Title: Trunking accessory and trunking equipped therewith
Inventor: BUARD YVON
IPC: H02G3/04
Filed: 1994-01-12
Granted: 1996-04-26
Abstract: Having the general shape of a section, the ducting accessory (25) according to the invention includes, on the one hand, a strip (26) for fastening it to the ducting (10) to be equipped and, on the other hand, a bead (28) for projecting from the latter. Application, in particular, to ducting used for housing and protecting electrical equipment. <IMAGE>
Patent AU-677614-B2 (AU)
Title: Methods of detecting Alzheimer's disease
Inventor: ROSES ALLEN D
IPC: C12Q1/68
Filed: 1993-09-30
Granted: 1997-05-01
Abstract: Methods of diagnosing or prognosing Alzheimer's disease in a subject are disclosed. The methods involve directly or indirectly detecting the presence or absence of an apolipoprotein E type 4 (ApoE4) isoform or DNA encoding ApoE4 in the subject. The presence of ApoE4 indicates the subject is afflicted with Alzheimer's disease or at risk of developing Alzheimer's disease. A novel immunochemical assay for detecting the presence or absence of the Apoliprotein E (ApoE) E4 allele in a subject is also disclosed.
Patent AU-751027-B2 (AU)
Title: Process for the preparation of mono-olefins from paraffinic hydrocarbons
Inventor: GRIFFITHS DAVID CHARLES
IPC: C07C29/151
Filed: 1999-09-07
Granted: 2002-08-08
Abstract: Process for producing a mono-olefin from a feedstock containing a paraffinic hydrocarbon comprising feeding a gaseous paraffinic hydrocarbon-containing feedstock and a molecular oxygen-containing gas to an autothermal cracker wherein they are reacted in the presence of a catalyst capable of supporting combustion beyond the normal fuel rich limit of flammability to produce a product comprising one or more mono-olefin(s) and synthesis gas, and wherein the autothermal cracker is operated at a temperature greater than 650° C. and at a pressure of greater than 5 bar absolute. The product is separated into a high pressure fuel gas stream comprising methane, carbon monoxide and hydrogen and a stream comprising one or more olefins and recovering the one or more olefin(s). The high pressure fuel gas stream comprising methane, carbon monoxide and hydrogen separated in the second step is passed to a Fischer-Tropsch reactor containing a Fischer-Tropsch catalyst, wherein the stream is converted to hydrocarbons and wherein the Fischer-Tropsch is operated at a pressure of between 5-50bar absolute. Thereafter at least part of the hydrocarbon product is recovered.
Patent AU-627038-B2 (AU)
Title: Voltage control oscillator with automatic current control
Inventor: KEHLER WALTER H JR
IPC: H03B5/12
Filed: 1990-05-17
Granted: 1992-08-13
Abstract: An automatic voltage-controlled oscillator (VCO) current control circuit, that senses a voltage in the VCO representative of the current of the VCO, compares that voltage to a reference voltage, and applies the voltage resulting from that comparison back to the VCO at a point therein that changes its bias state in such a manner as to maintain the noise level in the VCO at a minimum and also maintains the power output of the oscillator substantially constant.
Patent AU-671184-B2 (AU)
Title: Polymerisable compositions containing tetraacrylates
Inventor: WOLF JEAN-PIERRE
IPC: C08G18/67
Filed: 1994-03-04
Granted: 1996-08-15
Abstract: Photopolymerisable mixtures containing     (a) a tetraacrylate of the formula I or II <IMAGE>  in which     R1 is a hydrogen atom or methyl,   X1 and X2, independently of one another, are each -O- or -CO-O-, R2 is a divalent, aliphatic, cycloaliphatic or aromatic radical of a diglycidyl compound no longer containing glycidyl ether or ester groups, A is a divalent aliphatic, cycloaliphatic or aromatic radical of a diisocyanate compound no longer containing isocyanate groups,   n is an integer from 1 to 8, and R3 is a tetravalent cycloaliphatic radical of a diepoxide compound no longer containing 1,2-epoxide groups bonded to the cycloaliphatic ring,   (b) at least one liquid, free-radical-polymerisable compound other than component (a), and   (c) a free-radical photoinitiator, are preferentially suitable for the production of three-dimensional articles by stereolithography.
Patent AU-577948-B2 (AU)
Title: Coupling for deformable tubes
Inventor: BUJES GEORGES
IPC: F16L19/04
Filed: 1986-05-27
Granted: 1988-10-06
Abstract: The coupling comprises a male sleeve (10) with an external screw thread, an inserted collar (8) which bears between the tube (2) and a female nut (1) surrounding and completely covering the collar, and an internal piece (14) of revolution, on which the previously widened tube (2) bears. The collar (8) and the inner piece (14) together define an annular space (16) which widens, and then is straight, and which comprises a first throat (19) receiving an O-ring seal, and a second throat (21) in which the tube (2) is anchored. A second seal (22) serves as an abutment at the bottom of the annular space (16), and the nut (1) is fixed onto the sleeve (10), pushing the tube (22) back against the collar (8). <IMAGE>
Patent AU-716358-B2 (AU)
Title: Device, system and method for on-line explosive deslagging
Inventor: ZILKA FRANCIS
IPC: F23J3/02
Filed: 1998-01-14
Granted: 2000-02-24
Abstract: A device, system and method permitting on-line explosives-based cleaning and deslagging of a fuel burning facility (31) such as a boiler, furnace, incinerator, or scrubber. A coolant, such as ordinary water, is delivered to the explosives (101) to prevent them from detonating due to the heat of the on-line facility. Thus, controlled, appropriately-timed detonation can be initiated as desired, and boiler scale and slag is removed without the need to shut down or cool down the facility.
Patent AU-772480-B2 (AU)
Title: Antisense therapy for hormone-regulated tumors
Inventor: GLEAVE MARTIN
IPC: C12Q1/6886
Filed: 2000-07-19
Granted: 2004-04-29
Abstract: A method is provided for treating hormone-regulated tumors (for example, breast and prostatic tumors) in mammals, including humans, by administration of an antisense ODN which is complementary to a portion of the gene encoding IGFBP-5. Using the Shionogi tumor model in vitro and in vivo, the administration of such an ODN was shown to reduce proliferation of tumor cells, and also to delay the progression to androgen independence. Thus, treatment of prostate cancer in mammals, including humans, and delay of the progression of prostate tumors to androgen independence is accomplished by administering to the mammal a therapeutically effective amount of an antisense oligodeoxynucleotide which is complementary to a portion of the nucleic acid sequence encoding IGFBP-5 and which hybridizes with such a sequence to inhibit expression of IGFBP-5. Specific antisense ODN's which are suitable for use in the method are GACCACGCTGATCACCAT (Seq. ID. No. 1), which is derived from the murine gene sequence, and CGCGGTGAGCAACACCAT (Seq. ID. No. 3) and AGGTCATGCAGCAGCCGC (Seq. ID No 4), which are derived from the human gene sequence.