baber/WOPTO huggingface dataset:
Patent CA-2330827-A1 (CA)
Title: Construction and use of catalogued nucleic acid libraries that contain advantageously adjusted representations of defined components
Inventor: SHORT JAY M
IPC: C07B61/00
Filed: 1999-06-03
Abstract: A process for constructing a catalogued nucleic acid library in which the proportional representation of the constituents is adjusted to advantage through the use of disclosed technologies for positive and negative selection.  The resultant benefit is that significantly fewer library constituents will need to be screened in order to identify a potentially desired constituent.  Moreover, library constituents that previously would have been essentially "lost" are now recoverable. Preferred embodiments of this invention include the cataloguing, normalization, and enrichment of library constituents. By way of example, but not limitation, this technology is serviceable for constructing a library that contains an adequate representation of desirable constituents that (1) are initially found in low-copy numbers within a sample source or (2) originate from an organism that is problematic to culture.  Applicable uses of this invention include any library-screening endeavor previously hindered by logistical impediments. By expanding previous logistical frontiers this invention allows for a novel generation of previously unattainable molecules - particularly molecules that are "unclonable" from conventional, unadjusted libraries - to now be detected, cloned, manipulated, expressed, studied, and used. By disclosing the construction and screening of high yielding nucleic acid libraries from mixed and uncultivated organisms, the instant technology eclipses former boundaries in the area of biological discovery and enables the full breadth of biological diversity to be accessed in the search for previously undiscovered genes and gene products. The benefits of the present invention are seen to extend to areas of diagnosis, medicine, agriculture, manufacturing, and academia.
Patent CA-2331972-A1 (CA)
Inventor: MASTINICK PHILIP ALAN
IPC: B41J33/00
Filed: 2001-01-19
Abstract: A ribbon mechanism mounted in the lid of a printer includes a ribbon carriage pivotally coupled to the lid for folding out of the lid by virtue of its mass when the lid is open and for folding in the lid as the lid is closed. A gear train is mounted on the ribbon carriage for driving the ribbon take up core. A thermal printhead is resiliently mounted in the ribbon carriage and automatically aligned against the platen with alignment tabs. The ribbon carriage is movably linked to a printer hinge by way of a linkage having an elongated slot at one end for slidably engaging an integral ribbon carriage post and with an aperture at the other end for pivotally mating with a lever arm provided on the printer hinge. The ribbon carriage post slides linearly inside the linkage slot between maximum "down"/maximum "up" positions at each end of the linkage slot, respectively.
Patent CA-2332908-A1 (CA)
Title: An integrated process for converting natural gas and gas field condensate into high valued liquid products
Inventor: BERLOWITZ PAUL JOSEPH
IPC: C10G2/00
Filed: 1999-05-28
Abstract: The instant invention is directed to an integrated process for producing a hydroisomerate in the presence of sulfur comprising the steps of (a) separating a natural gas into a first stream comprising a C5+ gas field condensate containing sulfur and a second stream comprising said natural gas having said a C5+ gas field condensate containing sulfur and a second stream comprising said natural gas having said a C5+ gas field condensate removed therefrom; (b) removing sulfur from said second stream; (c) subjecting said second stream to a synthesis gas generation process to produce synthesis gas; (d) subjecting said synthesis gas to a hydrocarbon synthesis process to produce hydrocarbons; (e) hydrotreating and hydroisomerizing said hydrocarbons of step; (d) in the presence of said first stream over a catalyst having an acidic functionality and comprising a Group VIII non-noble metal or tungsten and a hydrocracking suppressant, wherein said hydrocracking suppressant is selected from the group consisting of Group IB metal, sulfur and mixtures thereof, and wherein when said hydrocracking suppressant is sulfur, said acidic functionality is an amorphous refractory oxide.
Patent CA-2333262-A1 (CA)
Title: Regioselective method for preparing cyclodextrin derivatives monosulfonylated at c-6
Inventor: LAW HO
IPC: C08B37/16
Filed: 1999-05-25
Abstract: The invention relates to a highly regioselective method for preparing a derivative of cyclodextrin, .beta.--cyclodextrin in particular, monosulfonylated at C-6, in which said cyclodextrin is caused to react with a sulfonylation agent, in an alkaline aqueous solution, in the presence of a metal salt able to form a co-ordination complex with the secondary hydroxyl groups of the cyclodextrin, and after the reaction said cyclodextrin derivative monosulfonylated at C-6 is recovered from the reaction mixture.   The monosulfonylated derivatives of cyclodextrins find particular application as starting material for access to monofunctionalized derivatives of cyclodextrins.
Patent CA-2333685-A1 (CA)
Title: Helmet
Inventor: LACROIX PHILIPPE
IPC: A42B3/32
Filed: 1999-06-02
Abstract: A helmet (10) comprising a shell (12) and a chin guard (14). The chin guard (14) has a first lateral portion (16), a second lateral portion (18) and a front portion (20) positioned between the first and second lateral portions (16, 18), said chin guard (14) being hingedly mounted to the shell (12) and moveable between an open position and a closed position. The chin guard (14)  has a locking mechanisms for locking the chin guard (14) to the shell (12) i n the closed position. The locking mechanism comprises a first locking member (24) applied at the first lateral portion (16) and provided for engaging the  shell (12) in the locking position; a second locking member (25) applied at the second lateral portion (18) and provided for engaging the shell (12) in a locking position; and an actuating member (24, 25) connected to said first a nd second locking members and provided for actuating the first and second locki ng members (24, 25). The front portion (20) has a first cavity (28) and a secon d cavity (30) faced towards each other. The actuating member comprises spaced apart first and second buttons (32, 34) located in said first and second cavities (28, 30) and provided to be pressed towards each other in order to actuate the locking members (24, 25).
Patent CA-2333891-A1 (CA)
Title: Conditional mutants of influenza virus m2 protein
Inventor: SKINNER ANITA
IPC: C12N15/09
Filed: 1999-07-09
Abstract: A mutant of Influenza virus M2 protein is described, which is capable of causing growth arrest in mammalian cells. Its use in a conditional cell deletion system is provided.
Patent CA-2335526-A1 (CA)
Title: Test slide for microscopes and method for the production of such a slide
Inventor: RICHARDSON TIMOTHY M
IPC: G02B21/34
Filed: 1998-06-24
Abstract: A test slide for the calibration, characterization, standardization, use and study of photon and electron microscopes. The slide is created by forming patterns with specific types of geometries on suitable substrates and these slides provide a standard for comparison of image forming capability of any type of microscope imaging system including, without limitation, light, UV, and X-ray photon microscopical imaging systems operating in transmission or reflection modes, and other microscope techniques. Microscopists can employ one of these slides to compare images of the slide which have been produced by the microscope system under consideration with a known, accurate, image of the slide to better understand the fidelity and accuracy of the microscope system under consideration. The test patterns can also comprise reference images which can be images created by a graphic artist or the like or which can be actual images of samples, these images being either two-dimensional or three-dimensional.
Patent CA-2336300-A1 (CA)
Inventor: KOPONEN ANITA
IPC: A61P11/02
Filed: 1999-06-30
Abstract: L'invention concerne des composés de formule (I) dans laquelle X¿1? ou X¿2? représente MeSO¿2?, l'un deux représentant hydrogène ou halogène, et X¿3? représente hydrogène ou halogène. On a découvert que ces composés sont utiles dans la prévention et le traitement des maladies respiratoires, notamment de l'asthme, du SDRA (syndrome de détresse respiratoire aiguë), des bronchopneumopathies chroniques obstructives, des rhinites allergiques et des troubles inflammatoires associés. L'invention concerne, en particulier, l'utilisation dudit composé dans la prévention et le traitement de l'asthme chez des patients présentant une résistance aux stéroïdes. L'invention concerne, en outre, des formulations pharmaceutiques utilisées dans le traitement de ces maladies.
Patent CA-2336479-A1 (CA)
Title: Secure session set up based on the wireless application protocol
Inventor: IMMONEN OLLI
IPC: H04L9/00
Filed: 1999-07-02
Abstract: Method, apparatus, memory card, and system for establishing a secure connection between a wireless communication apparatus and a data communication apparatus based on a wireless application protocol. The wireless communication apparatus is provided with contact means for receiving information from a separate unit provided with memory means.  The memory means comprising information to control the access of the wireless communication apparatus through a wireless communication network connected to said data communication apparatus.
Patent CA-2340092-A1 (CA)
Inventor: HARLING JOHN DAVID
IPC: A61P25/32
Filed: 1999-08-06
Abstract: L'invention concerne un composé représenté par la formule (I), des sels de celui-ci ou des solvates de celui-ci. Dans cette formule, R?1¿ représente hydrogène, C¿1-6?alkyle (éventuellement substitué par hydroxy ou par C¿1-4?alcoxy), C¿1-6?alcényle, C¿1-6?alcynyle, C¿1-6?alkylCO-, formyle, CF¿3?CO- ou C¿1-6?alkylSO¿2?-; R?2¿ représente hydrogène, ou jusqu'à trois substituants sélectionnés dans le groupe constitué par halogène, NO¿2?, CN, N¿3?, CF¿3?O-, CF¿3?S-, CF¿3?CO-, CF¿3?SO¿2?, trifluorométhyldiazirinyle, C¿1-6?alkyle, C¿1-6?alcényle, C¿1-6?alcynyle, C¿1-6?perfluoroalkyle, C¿3-6?cycloalkyle, C¿3-6?cycloalkyl-C¿1-4?alkyle-, C¿1-6?alkylO-, C¿1-6?alkylCO-, C¿3-6?cycloalkylO-, C¿3-6?cycloalkylCO-, C¿3-6?cycloalkyl-C¿1-4?alkylO-, C¿3-6?cycloalkyl-C¿1-4?alkylCO-, phényle, phénoxy, benzyloxy, benzoyle, phényl-C¿1-4?alkyle-, C¿1-6?alkylS-, C¿1-6?alkylSO¿2?-, (C¿1-4?alkyl)¿2?NSO¿2?-, (C¿1-4?alkyl)¿2?NHSO¿2?-, (C¿1-4?alkyl)¿2?NCO-, (C¿1-4?alkyl)¿2?NHCO-, et CONH¿2?; ou NR?5¿R?6¿ où R?5¿ représente hydrogène ou C¿1-4?alkyle, et R?6¿ représente hydrogène, C¿1-4?alkyle, formyle, -CO¿2?C¿1-4?alkyle ou COC¿1-4?alkyle; ou deux groupes R?2¿ forment ensemble un noyau carbocyclique saturé ou insaturé et non substitué ou substitué par -OH ou O=; les deux groupes R, les deux groupes R?3¿, et les deux groupes R?4¿ représentent chacun indépendamment hydrogène, C¿1-6?alkyle, C¿1-6?alcényle, benzyle, ou phényle, ou les deux groupes R et/ou les deux groupes R?3¿ et/ou les deux groupes R?4¿ forment ensemble un groupe C¿3-6?spiroalkyle, à condition qu'au moins l'un des groupes R, R?3¿ ou R?4¿ soit autre qu'hydrogène; et X est sélectionné dans le groupe constitué par hydrogène, halogène, cyano, CF¿3?, alkyle et alcoxy; à condition que lorsque X représente hydrogène, les deux groupes R ne représentent pas tous les deux hydrogène. Ces composés sont utiles dans le traitement et la prophylaxie de l'épilepsie, des migraines et d'autres troubles.
Patent CA-2340785-A1 (CA)
Inventor: GUEGLER KARL J
IPC: C12N9/90
Filed: 1999-08-13
Abstract: The invention provides a human cyclophilin-type peptidyl-prolyl cis/trans isomerase (CPCI) and polynucleotides which identify and encode CPCI. The invention also provides expression vectors, host cells, antibodies, agonists , and antagonists. The invention also provides methods for diagnosing, treatin g or preventing disorders associated with expression of CPCI.
Patent CA-2343017-A1 (CA)
Inventor: KAWAMURA SHINICHI
IPC: A01N43/80
Filed: 1999-09-02
Abstract: L'invention concerne des composés hétérocycliques condensés de la formule générale (I) dans laquelle T représente un carbone ou un azote; lorsque T représente un carbone, la liaison entre T et A est une liaison double, la liaison entre A et Y est une liaison simple et Y représente de l'oxygène, du soufre ou un NH éventuellement substitué; ou lorsque T représente un azote, la liaison entre T et A est une liaison simple, la liaison entre A et Y est une liaison double et Y représente un azote ou CH éventuellement substitué; A représente un azote ou CH éventuellement substitué; R?1¿ représente un hydrogène, un alkyle, un haloalkyle, un hydroxyméthyle, un nitro ou un cyano; R?2¿ représente un hydrogène, un halogène, un alkyle, un haloalkyle, un hydroxyméthyle, un nitro, un cyano ou analogue; R?3¿ représente un hydrogène, un halogène, un alkyle, un haloalkyle, un hyroxyméthyle, un nitro, un cyano ou analogue; R?4¿ représente un hydrogène, un halogène, un alkyle, un haloalkyle, un hydroxyméthyle, un nitro ou un cyano ; et Q représente un noyau hétérocyclique saturé ou insaturé à 5 ou 6 chaînons contenant un à quatre atomes d'azote, ou un groupe cyclopentylidèneamino saturé ou insaturé contenant un ou deux hétéroatomes d'azote et un hétéroatome d'oxygène ou de soufre.
Patent CA-2345372-A1 (CA)
Inventor: LAGRANGE ALEXANDRE
IPC: G01N33/566
Filed: 1999-10-04
Abstract: A device for reading a biochip including plural molecular recognition areas and plural optical positioning marks, associated with recognition areas. The device includes an optical head capable of projecting excitation light onto the biochip. A device is provided to effectuate relative displacement between the head and the biochip. A first optical analysis system is associated with the optical head to receive any light arriving from recognition areas. A second optical positioning system is associated with the optical head to receive any light from at least one guide track and/or optical positioning mark. A device is further provided for servocontrolling scanning by the optical head. Such a device may find particular application to biological and chemical analysis.
Patent CA-2346438-A1 (CA)
Title: Utilisation of dialkylfumarates for treating host-versus-graft reactions and auto-immune diseases
Inventor: STREBEL HANS-PETER
IPC: A61P5/14
Filed: 1999-10-29
Abstract: The present invention relates to the use of certain dialkyl fumarates for the preparation of pharmaceutical preparations for use in transplantation medicine or for the therapy of autoimmune diseases and said compositions in the form of micro-tablets or pellets. For this purpose, the dialkyl fumarates may also be used in combination with conventional preparations used in transplantation medicine and immunosuppressive agents, especially cyclosporines.
Patent CA-2349063-A1 (CA)
Title: Process for producing a polymer of an ae-olefin and lubricant
Inventor: MINAMI YUTAKA
IPC: C08F4/659
Filed: 2001-05-29
Abstract: A process for producing a polymer of an .alpha.-olefin which comprises polymerizing an .alpha.-olefin having at least 4 carbon atoms in the presence of a catalyst for producing polymers of olefins which comprises (A) a specific metal compound and (B) at least one compound selected from (b-1) an organoaluminum oxy compound and (b-2) an ionic compound.      The polymer of an .alpha.-olefin is useful as a component of lubricant.
Patent CA-2351366-A1 (CA)
Inventor: WEISSMAN STEVEN I
IPC: G06Q20/22
Filed: 1999-11-16
Abstract: A data processing system and method are provided for allocating all charged transactions, accrued interest attributable to each charged transaction, and payments made by respective credit cardholders, to sub-accounts specifically designated by the cardholder. In particular, at the point of purchase (Figure 4), the cardholder specifies one or more designated sub-accounts to which the charge is to be allocated. The data processing system allocates to each designated sub-account all charges specified, as well as all interest charges that accrue as to each designated sub-account to which the interest charges are attributable. As each periodic payment is made by the cardholder, the cardholder has the capability of specifying the designated sub-account or portion thereof which is being paid (Figure 5). The data processing system allocates each payment to the designated sub-account(s) specified by the cardholder and calculates interest charges allocable to each designated sub-account as adjusted by each payment by the cardholder.
Patent CA-2351454-A1 (CA)
Inventor: SCHMIDT KRISTINA
IPC: G01N21/552
Filed: 1999-11-16
Abstract: The invention relates to a set-up of measuring instruments for the parallel readout of SPR sensors. The aim of the invention is to provide a measuring arrangement for the parallel readout of a plurality of SPR sensors wherein the readout process should be terminated within an integration period of less than 30 minutes. To this end, a wavelength-selective component (5) and an optical imaging system (L2, L3) are arranged downstream of a light source (3). Said optical imaging system (L2, L3) is designed in such a manner that at a first wavelength it guarantees a parallel illumination of the light incidence ends of waveguides (13) which are provided with SPR-compatible sensor zones and that the light emitted from the individual optical waveguides (13) can be simultaneously imaged onto a CCD chip (20) via an optical device (L4) in such a way that the light emitted by every single optical waveguide (13) can be detected by a respective plurality of adjacent CCD pixels of the CCD chip (20). A light intensity value can be calculated from these pixel arrays by means of an image processing software. Once the intensity value, adjusted wavelength and coordinate in the waveguide array (10) is stored by a memory (30) via a control line (31), the wavelength-selective component (5) can be adjusted to a second and freely selectable further optical wavelength.
Patent CA-2352693-A1 (CA)
Inventor: KOBAYASHI MASAKI
IPC: G02F1/133
Filed: 2001-07-05
Abstract: To provide a liquid crystal display apparatus and computer apparatus allowing power consumption to be effectively reduced. The refresh rate of an LCD panel is changed as the brightness of the LCD panel changes. When the brightness of the LCD panel is decreased, the refresh rate is also decreased. In addition, whether the power source of the apparatus is AC or DC  is determined based on whether an AC adapter is attached or not. When the DC power source is used, the brightness and refresh rate of the LCD panel is lowered with respect to when the AC power source is used.
Patent CA-2353268-A1 (CA)
Title: Moisture-curing reactive hot-melt adhesive for weather strip flocking, flocked weather strip, and process for producing flocked weather strip
Inventor: YAMADA MASASHI
IPC: C08G18/10
Filed: 2001-07-19
Abstract: An adhesive, a flocked weather strip, and a process for producing the weather strip. The adhesive is a moisture-curing reactive hot-melt adhesive for weather strip flocking, which comprises as the main component a urethane prepolymer containing isocyanate groups, the adhesive having a dielectric constant at 25°C of 3 to 10 and a melting point of 40°C to 150°C . The flockedweather strip comprises a substrate and piles flocked thereon through the moisture-curing reactive hot-melt adhesive. The process for producing the flocked weather strip comprises thermally melting the moisture-curing reactive hot-melt adhesive, applying the melt to a substrate in a thickness of 40 to 150 µm, electrostatically flocking piles in the resulting layer of the molten adhesive, cooling the adhesive to solidify the same and fix the flocks to the substrate, and then cutting the substrate into a given size. The adhesive is suitable for use in the flocking of a weather strip substrate and enables piles flocked in a melt of the adhesive to tenaciously bond to the weather strip substrate in a short period of time. The weather strip has excellent sliding resistance and is especially suitable for use in motor vehicles.
Patent CA-2354316-A1 (CA)
Title: Container having a preshaped end closure
Inventor: BOATWRIGHT FLOYD H
IPC: B65D51/26
Filed: 2001-07-26
Abstract: A tubular container for vacuum packaging products is provided according to the present invention that includes an overcap secured to at least one of the opposed ends of a tubular container that defines a bias member for biasing a membrane- type flexible lid inwardly towards products contained within the tubular container before a vacuum is applied. The flexible lid is maintained in a biased shape until the bias member is removed. As such, the flexible lid is sufficiently restrained during the vacuum packaging process, thus preventing the breakage of products located adjacent the flexible lid.
Patent CA-2358604-A1 (CA)
Title: Method of measuring and improving xdsl transmission characteristic
Inventor: SUDO MINORU
IPC: H04B17/00
Filed: 2001-10-10
Abstract: In accordance with the present invention, a system for measuring the transmission characteristic of an xDSL system that implements high-speed data communication over existing copper wires connecting an office and a subscriber includes a pulling device included in the outside line of an xDSL circuit, which is installed in an office, for pulling a subscriber line. A noise level measuring circuit measures the level of cross-talk noise on the subscriber line. A decision circuit determines, based on the level of cross-talk noise measured, whether or not the subscriber line is usable.
Patent CA-2359479-A1 (CA)
Inventor: SEDLACEK HANS-HARALD
IPC: A61K48/00
Filed: 2000-01-05
Abstract: L'invention concerne un complexe à base de protéines spécifiquement complexantes n'intervenant pas de manière naturelle, qui contiennent les constituants suivants: a) au moins un ligand spécifique d'une structure cible; b) au moins une protéine contenant un domaine de dimérisation muté, ledit domaine de dimérisation muté ayant été dérivé par mutation d'un domaine de dimérisation intervenant de manière naturelle, ledit domaine de dimérisation muté peut entrer de manière spécifique en interaction avec le constituant b) et le constituant c) est lié de manière covalente au constituant d); et d) au moins un effecteur. L'invention concerne en outre l'utilisation et la préparation de ces complexes, ainsi que des produits de recombinaison d'acide nucléique codant pour les protéines mentionnées et leur utilisation.
Patent CA-2359678-A1 (CA)
Inventor: MANSKE GREG
IPC: A61K45/06
Filed: 2000-01-12
Abstract: L'invention concerne de nouvelles compositions et techniques permettant de traiter des animaux et des humains infectés par des parasites Apicomplexan. L'invention concerne, plus spécifiquement, le traitement d'une infection provoquée par un parasite Apicomplexan par administration de s-triazines, telles que l'atrazine, à un animal ou un humain infecté. L'invention concerne également des compositions pharmaceutiques renfermant des quantités thérapeutiquement efficaces de s-triazines, telles que l'atrazine, utiles pour traiter des infections parasitaires.
Patent CA-2359853-A1 (CA)
Title: Polypeptides mutants de chimiokine beta-10 humaine
Inventor: LI YULING
IPC: A61K38/00
Filed: 2000-01-07
Abstract: La présente invention concerne des polypeptides de chimiokine Bêta-10 humaine et l'ADN (ARN) codant pour lesdits polypeptides, ainsi qu'une méthode permettant de produire ces polypeptides à l'aide de techniques de recombinaison. L'invention concerne également des méthodes d'utilisation de ces polypeptides de chimiokine dans le traitement de la leucémie, des infections chroniques, des maladies auto-immunes, des troubles de type fibrose, du psoriasis et dans la cicatrisation de lésions. L'invention concerne en outre des antagonistes dirigés contre lesdits polypeptides de chimiokine, ainsi que leur utilisation thérapeutique dans le traitement de la polyarthrite rhumatoïde, des maladies auto-immunes et des maladies inflammatoires et infectieuses chroniques, des réactions allergiques, de la fièvre indépendante des prostaglandines et de l'insuffisance médullaire.