baber/WOPTO huggingface dataset:
Patent CA-3092916-A1 (CA)
Inventor: STRIBERNY BERND KETELSEN
IPC: C12N9/52
Filed: 2019-03-07
Abstract: L'invention concerne une composition comprenant une protéinase ou un fragment enzymatiquement actif correspondant, ladite protéinase comprenant la séquence d'acides aminés SEQ ID NO : 1 ou comprenant une séquence d'acides aminés qui est à au moins environ 70 % identique à SEQ ID NO : 1. Dans ladite composition, i) la concentration de calcium libre est = environ 80 µM, ou ii) la concentration de sel monovalent est = environ 20 mM. Dans ces conditions, les protéinases et leurs fragments enzymatiquement actifs sont thermolabiles de manière inductible. L'invention concerne en outre des échantillons comprenant un ou plusieurs polypeptides et une protéinase ou un fragment enzymatiquement actif correspondant, ladite protéinase comprenant la séquence d'acides aminés SEQ ID NO : 1 ou comprenant une séquence d'acides aminés qui est au moins à environ 70 % identique à SEQ ID NO : 1. Dans ledit échantillon, i) la concentration de calcium libre est = environ 80 µM ; ou ii) la concentration de sel monovalent est = environ 20 mM. L'invention concerne en outre des procédés comprenant l'inactivation de telles protéinases ou de fragments enzymatiquement actifs correspondants, ledit procédé comprenant l'étape de chauffage de l'échantillon pour inactiver ladite protéinase ou ledit fragment enzymatiquement actif, i) la concentration de calcium libre dans ledit échantillon étant = environ 80 µM ; ou ii) la concentration de sel monovalent dans ledit échantillon étant = environ 20 mM.
Patent CA-3093398-A1 (CA)
Title: Systems and methods for creating curved paths through bone and modulating nerves within the bone
Inventor: PATEL SAMIT
IPC: A61B18/14
Filed: 2013-11-01
Abstract: ABSTRACT A system configured for navigation and treatment within a vertebral body includes an introducer. The introducer includes a proximal handle and an elongate tube including a channel extending from the proximal handle to a distal end of the introducer. The system further includes a straight stylet configured to be received in the channel of the introducer. The straight stylet includes a sharp-tipped distal end that, when installed fully within the introducer, extends slightly beyond the distal end of the introducer. The system further includes a steerable radiofrequency energy delivery probe configured to be inserted through the introducer after removal of the straight stylet. The steerable radiofrequency energy delivery probe includes a proximal handle and an elongate tube that includes a slotted distal end portion that is configured to bend upon actuation. The steerable radiofrequency energy delivery probe further includes two or more electrodes, and a temperature sensor. Date Recue/Date received 2020-09-17
Patent CA-3095120-A1 (CA)
Inventor: BENEDETTI ALESSANDRO
IPC: B09B5/00
Filed: 2019-03-29
Abstract: Il est décrit un ensemble d'ouverture de capsule permettant d'ouvrir une capsule usagée. Le corps de capsule a une ouverture, et il s'étend autour d'un axe de capsule longitudinal définissant une chambre fermée par un couvercle. L'ensemble comprend un dispositif de coupe de capsule usagé ayant un couteau ou une lame de coupe, un dispositif de blocage de capsule usagé saisissant la capsule usagée dans une position prédéterminée qui définit un siège de verrouillage et laissant exposée l'ouverture de capsule fermée par le couvercle; un dispositif de déplacement de capsule usagé ayant un chariot qui supporte le dispositif de blocage de capsule usagé. Le chariot déplace le dispositif de blocage de capsule usagé par rapport au dispositif de coupe de capsule usagé. Un mouvement relatif se produit le long d'un trajet prédéterminé comprenant au moins un étirement linéaire dirigé le long d'une direction parallèle ou coïncidant avec l'axe de capsule longitudinal. Le couteau, pendant le mouvement le long de l'étirement de trajet linéaire, coupe une partie de couvercle le long d'une ligne de coupe prédéterminée pour ouvrir la chambre de capsule.
Patent CA-3095764-A1 (CA)
Inventor: ASANTE SAMUEL ASIEDU
IPC: A21C11/06
Filed: 2019-05-03
Abstract: La présente invention concerne un appareil pour séparer un ruban de pâte gaufrée non cuite en morceaux séparés ayant un motif/une forme similaire au motif gaufré. L'appareil comprend une paire de rouleaux espacés pour recevoir un ruban de pâte entre eux. L'un des rouleaux a un motif gaufré sur sa surface pour gaufrer le ruban de pâte avec le motif. Le gaufrage de surface et l'espacement entre les rouleaux maintiennent l'intégrité structurelle du ruban gaufré de pâte. L'appareil comporte deux bras rotatifs espacés pour recevoir le ruban de pâte gaufré entre eux. Une pluralité de doigts espacés s'étendent vers l'extérieur le long de la longueur de chacun des bras et sont conçus pour déchirer la pâte, sans coller, en morceaux de pâte représentant des formes gaufrées dans le ruban de pâte. Les morceaux de pâte peuvent être séchés, et des morceaux à motifs sont séparés pour une expansion en trois dimensions par cuisson.
Patent CA-3097281-A1 (CA)
Title: R-fadrozole for use in the treatment of aldostonerism
Inventor: STEELE RONALD EDWARD
IPC: A61K31/437
Filed: 2019-05-02
Abstract: The present invention relates to a composition for use in the treatment of a disease or disorder, wherein said disease or disorder is preferably a disease or disorder in which aldosterone overexposure contributes to the symptoms of said disease or disorder, said composition comprises a compound which is (R)-(+)-5-(p-cyanophenyl)-5,6,7,8- tetrahydroimidazo[1,5-a]pyridine or a pharmaceutically acceptable salt thereof, wherein preferably said compound is (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazolium[1,5- a]pyridine dihydrogen phosphate, and wherein said compound has an enantiomeric excess (ee) of the (R) form higher than or equal to 97%, and wherein said composition is administered once daily to a subject in need thereof. The invention further relates to a pharmaceutical composition comprising a daily dosage of said compound in a fixed-unit dosage form and to a combination comprising (i) said pharmaceutical composition or said compound; and (ii) instructions for administration of said pharmaceutical composition or said compound once per day.
Patent CA-3100403-A1 (CA)
Title: Stator element of a progressive cavity pump and progressive cavity pump
Inventor: GARNIER PIERRE
IPC: F04C2/107
Filed: 2019-05-16
Abstract: The invention relates to a stator element of a progressive cavity pump. The stator element comprises: · an armature tube (20) having a longitudinal axis (A-A), an internal face (22) and an extreme face (24), and · an elastomer lining attached to the internal face of the armature tube, characterized in that at least one portion of the armature tube (20) has a substantially constant thickness (e) and in that said portion of the armature tube (20) is deformed so that it comprises at least a first relief (28) and a second relief (30), the first relief (28) having the form of a helical strip having a pitch to the right with respect to the longitudinal axis (A-A), the second relief (30) having the form of a helical strip having a pitch to the left with respect to the longitudinal axis (A-A) of the armature tube, the first and second reliefs joining in at least one section (32).
Patent CA-3101387-A1 (CA)
Title: Conducting transactions between local and remote computer systems
Inventor: YUEN RAYMOND
IPC: H04L12/16
Filed: 2020-12-01
Abstract: ABSTRACT A local computer system connects to a remote computer system of a remote component of FM1. The local computer system stores an account identifier of a single account at the rernote component of financial market infrastructure (FMI).  The local computer system communicates with the remote computer system using the account identifier to clear and settle trades with the remote component of FMI. The local computer system stores local node identifiers for local nodes.  The local computer system communicates with each local node using a local node identifier. The local computer system communicates local transaction data with local nodes with reference to the local node identifiers. The local computer system communicates remote transaction data with the remote computer system with reference to local node identifiers and the account identifier of the single account. The local computer system synchronizes the local transaction data with the remote transaction data. Date Recue/Date Received 2020-12-01
Patent CA-3101700-A1 (CA)
Title: Methods and compositions involving bucindolol for the treatment of atrial fibrillation
Inventor: BRISTOW MICHAEL
IPC: A61K31/4045
Filed: 2019-05-24
Abstract: The current methods and compositions relate to treatment of atrial fibrillation with bucindolol in patients, including patientswith heart failure, after being determined to be homozygous Arg389 in the ß1 adrenergic receptor gene.
Patent CA-3109478-A1 (CA)
Inventor: FORSELL PETER
IPC: A61B17/04
Filed: 2009-01-29
Abstract: 87466950 Abstract An implantable device for the treatment of acid reflux disease has a body including an outer surface adapted to rest against a patient's fundus wall. The device, when implanted in a patient, fills a volume in the patient's abdomen in the cardia area and above the cardia of the patient, when standing. The body prevents the cardia from moving through the diaphragm opening into the thorax, thereby preventing reflux by keeping the abdominal pressure supporting the cardia sphincter muscle. The device may be affixed to stomach tissue. The device may also be invaginated or otherwise indirectly secured in position. Date recue/Date Received 2021-02-17
Patent CA-3109832-A1 (CA)
Title: Bypass turbomachine
Inventor: TESSIEREAU ANTONIN ETIENNE DIEGO
IPC: F16B19/02
Filed: 2019-09-04
Abstract: The invention relates to an assembly for a turbomachine of longitudinal axis comprising a first annular wall (24), panels (38) being arranged around the longitudinal axis (A) and extending in a manner radially facing said first annular wall (24) so as to form a flow surface for an airflow, each panel (38) being secured to the first annular wall (24) by at least one fastening member (72) that passes through an orifice in the panel (38) and is secured to the first annular wall (24) by means of a socket and a stud forming a spacer.
Patent CA-3116070-A1 (CA)
Inventor: MEUDAL NICOLAS
IPC: B01F33/40
Filed: 2019-10-17
Abstract: Liquid effluent treatment module (100) comprising at least one tank portion (110a, 110b) suitable for receiving a plurality of packing elements that may receive a biological material, the tank portion (110a, 110b) defining a horizontal longitudinal axis and comprising at least one effluent feed, characterized in that the tank portion (110a, 110b) further comprises: ° at least one line for collecting treated effluent (130) arranged in a central part of the tank portion and parallel to the horizontal longitudinal axis, ° at least one air injection line (120) arranged in a lower part (112) of the tank portion, off-centered and parallel to the line for collecting treated effluent (130), so as to give rise to a spiral movement of the liquid effluents.
Patent CA-3120100-A1 (CA)
Inventor: WOODS TIMOTHY J
IPC: F16H1/46
Filed: 2021-05-27
Abstract: In a motor that converts linear force into rotational force, a series of planetary sprockets crosses an equatorial contained by a very large sun wheel. The sun wheel is a rigidly fixed sprocket chain of multiple strands that serves as an ersatz internal gear and is supported by an atlas wheel and held to alignment be angel wheels. A Saturn sprocket, having its center removed, allows room for a mars shaft and a titan shaft to cross through it. The inner face of the Saturn sprocket rides on a mars shaft and a titan shaft, while its outer edge 'floats' between the sun wheel chain and a chain that travels between a venus sprocket and an earth sprocket, the which chain being itself comprised of multiple strands. Four of the series of planet sprockets (mercury, venus, earth, mars) have their shafts fixed, and serve as ersatz 'gears' completing most of a force's feedback loop. The mars shaft also serves as a fulcrum about which levers swing. A multi-strand chain that travels between a venus wheel and an earth wheel, imposes a direction of counter-rotation upon an adjacent Saturn sprocket that engages the venus-earth chain. Lever arms are mounted via bearings on the mars shaft, and on a titan shaft which bears against the inner face of the Saturn sprocket which also engages the sun wheel. A further chain travels between a mars sprocket and a titan sprocket for in-common directional rotation. As the titan shaft is moved 'up' or 'down' - according to the direction of the lever arms - so also does the sun wheel (as does the Saturn wheel). The sun wheel revolves and moves the mercury sprocket at the other side of the motor, which moves successively the venus sprocket, the earth sprocket, the mars sprockets, the Saturn sprocket, and the titan sprocket. For a more robust motor, gears are used in lieu of certain sprockets to achieve the same feedback loop purposes. This environmentally clean motor operates without fuel, in virtually any non-solid medium, until force is withdrawn from the lever arms.
Patent CA-3121706-A1 (CA)
Title: Edible products
Inventor: HORNBY LEWIS
IPC: A23L2/02
Filed: 2019-12-23
Abstract: The present invention relates to edible products, suitable for use as confectionery and having therapeutic uses. We describe a composition for the preparation of an edible product, the composition comprising 0.2 wt.% to 3 wt.% of at least one polysaccharide gelling agent, the balance being water. In preferred composition, the at least one polysaccharide is at least one of agar, pectin, locust bean gum, gellan gum and carrageenan. The compositions preferably comprise 0.5 wt.% to 2.00 wt.% agar and 0.05 to 1.0 wt.% of a galactomannan polysaccharide; the balance being water; preferably wherein the galactomannan polysaccharide is present in an amount of from 10% to 40% the amount of agar.
Patent CA-3124261-A1 (CA)
Inventor: FRANCOIS EMMANUEL C
IPC: H05B1/02
Filed: 2019-08-27
Abstract: Un système de surveillance d'un état d'un article comprenant un revêtement conducteur comprend : un dispositif de mesure pouvant être connecté électriquement au revêtement conducteur de l'article conçu pour détecter une propriété électrique du revêtement conducteur ; et un processeur connecté électriquement au dispositif de mesure. Le processeur est configuré pour : recevoir la propriété électrique détectée du revêtement conducteur en provenance du dispositif de mesure ; déterminer une résistance du revêtement conducteur sur la base de la propriété électrique détectée reçue ; déterminer une durée de vie utile restante estimée de l'article sur la base de la résistance déterminée du revêtement conducteur ; et générer un signal de sortie représentant la durée de vie utile restante estimée déterminée.
Patent CA-3124651-A1 (CA)
Title: Specific co-aggregation inhibition by arginine
Inventor: DAEP CARLO
IPC: A61K31/198
Filed: 2019-12-19
Abstract: Methods of selectively inhibiting co-aggregation of commensal and pathogenic bacteria in a population of bacteria that comprises commensal and pathogenic bacteria, such as in an individual's oral cavity are disclosed. Methods of reducing biofilm in an individual's oral cavity are disclosed. Methods of inhibiting biofilm formation in a population of bacteria that comprises commensal and pathogenic bacteria are disclosed. Methods of identifying a compound or composition that enhances the selective inhibition of co-aggregation of commensal and pathogenic bacteria by arginine or an arginine oligomer are also disclosed. Methods of identifying a compound or composition that enhances the selective inhibition of biofilm formation of commensal and pathogenic bacteria by arginine or an arginine oligomer are disclosed.
Patent CA-3125734-A1 (CA)
Title: Membrane distillation module and membrane distillation apparatus using same
Inventor: HASHIMOTO TOMOTAKA
IPC: C02F1/44
Filed: 2020-01-10
Abstract: The purpose of the present invention is to provide: a membrane distillation module with excellent stability of water treatment ability over time as a result of wetting being controlled; and a membrane distillation apparatus comprising the same. Provided is a membrane distillation module that comprises a housing and multiple porous hollow fiber membranes, both ends of which are bonded and fixed to the housing, wherein: the water contact angle of the outer surfaces of the porous hollow fiber membranes is at least 90°; a hydrophobic polymer adheres to at least some of the areas of the porous hollow fiber membranes that are not bonded and fixed; and when the area from one end to the other end of the non-bonded-and-fixed area of each of the inner surface and the outer surface of the porous hollow fiber membranes in the longitudinal direction is expressed as 0% to 100%, the amount of hydrophobic polymer per membrane area adhering to the area that is 0-5% from the one end and/or the amount of hydrophobic polymer per membrane area adhering to the area that is 95-100% from the one end is greater than the amount of hydrophobic polymer per membrane area that is present in the area that is 40-60% from the one end.
Patent CA-3125839-A1 (CA)
Inventor: COWEN NEIL M
IPC: A61P3/00
Filed: 2015-11-12
Abstract: Provided are immediate or prolonged administration of certain potassium ATP (KATT) channel openers, optionally in combination with growth hormone, to a subject to achieve novel pharmacodynamic, pharmacokinetic, therapeutic, physiological, metabolic and compositional outcomes in the treatment of diseases or conditions involving KATP channels. Also provided are pharmaceutical formulations, methods of administration and dosing of KATP channel openers that achieve these outcomes and reduce the incidence of adverse effects in treated individuals. Further provided are methods of co- administering KATP channel openers with other drugs (e.g., in combination with growth hormone) to treat diseases of humans and animals (e.g., Prader-Willi Syndrome (PWS), Smith~ Magenis syndrome (SMS), and the like.
Patent CA-3125914-A1 (CA)
Inventor: SUTTON JEFFREY
IPC: G01N21/76
Filed: 2020-01-07
Abstract: L'invention concerne un dispositif et un procédé de séparation du sang, comprenant la sédimentation du plasma à l'aide de PVA. Le dispositif comprend un récipient interne enfermé dans un récipient externe, l'alignement des ouvertures respectives permettant à l'échantillon de sortir du récipient interne et d'entrer dans une structure de réaction. La structure de réaction comprend une ou plusieurs couches, chacune ayant une ou plusieurs parties contenant chacune des concentrations d'un ou de plusieurs produits chimiques.
Patent CA-3126919-A1 (CA)
Title: Data packets comprising random numbers for controlling fluid dispensing devices
Inventor: ROSSI JOHN
IPC: B41J2/135
Filed: 2019-02-06
Abstract: In some examples, a fluid dispensing device includes a reservoir containing a fluid, fluidic actuators, and an interface to receive a data packet comprising information to control activation of the fluidic actuators, the data packet comprising a random number generated by a random number generator.
Patent CA-3130621-A1 (CA)
Inventor: GUILLET NICOLAS
IPC: H01M10/633
Filed: 2021-09-14
Abstract: L'invention concerne un procédé de gestion du comportement thermique d'une batterie (BATT), ledit procédé consistant à : - Employer un modèle thermique (MOD_TH) de la batterie, configure pour estimer, à chaque instant, une puissance thermique (Wth) générée par la batterie en fonction d'une puissance électrique e (Wect, 1 mesurée traversant la batterie, , ¨ l ledit modèle thermique comportant une loi à la charge et une loi à la décharge, chaque loi étant basée sur l'état de charge de la batterie (SoC) et sur sa température (T) et intégrant la constante de temps (t) de la batterie, - Contrôler (CTRL) la puissance thermique (Wth) générée par la batterie.
Patent CA-3131534-A1 (CA)
Title: Athletic training system combining cognitive tasks with physical training
Inventor: SACHS SUN
IPC: G16H20/70
Filed: 2020-02-24
Abstract: A method for cognitive brain training, psychological motivation, and recovery to be used in conjunction with physical exercise in order to reduce the effects of mental and physical fatigue and improve athletic performance. A plurality of input devices integrate ergonomically with different sports so as not to limit movement, eye -hand coordination or negatively impact physical training. Software, executable on a portable computing device is configured for a sport, enabling an athlete to perform physical and cognitive tasks at the same time. Metrics, formulas and algorithms combine the athlete's self-rated performance with real-time cognitive and physiological output metrics to provide reports of the athlete's performance for each workout and for all workouts overtime. Mental recovery and motivation protocols used to help athletes stay on task and recover from the physical training. Cognitive fatigue self-assessment tests used to help athletes determine their current level of mental fatigue and readiness to train.
Patent CA-3133209-A1 (CA)
Title: Composition pharmaceutique pour le traitement de l'anevrisme de l'aorte
Inventor: UNNO NAOKI
IPC: A61K31/4704
Filed: 2020-03-13
Abstract: La présente invention cherche à résoudre le problème qui est de fournir un agent thérapeutique pour l'anévrisme de l'aorte abdominale, cet agent thérapeutique rendant possible un traitement médicamenteux. La présente invention concerne un agent thérapeutique pour l'anévrisme de l'aorte, l'agent thérapeutique comprenant comme principes actifs : du (-)-6-[3-[3-cyclopropyl-3-[(1R,2R)-2-hydroxycyclohexyl]ureido]propoxy]-2(1H)-quinolinone ou un sel de ce dernier, ou un solvate de ces derniers ; et une statine.
Patent CA-3134313-A1 (CA)
Title: Methods of identifying hiv patients sensitive to therapy with gp120 v3 glycan-directed antibodies
Inventor: MOLDT BRIAN
IPC: A61P31/18
Filed: 2020-05-18
Abstract: Provided are methods for identifying patient populations infected with HIV that can be targeted by antibodies that bind to HIV gl20 V3 glycan region.
Patent CA-3137009-A1 (CA)
Title: Dual injection for hydrocarbon reservoir management
Inventor: ALSHEHRI AMAR JABER M
IPC: E21B43/20
Filed: 2020-04-14
Abstract: In a dual injection method for hydrocarbon reservoir management, a production well (102a, 102b) is formed from a surface to a hydrocarbon-bearing zone (104) in the reservoir. A first injection well (106a) and a second injection well (106b) are formed from the surface to a first depth and a second depth, respectively, in a water-bearing zone (108) below the hydrocarbon-bearing zone, the second depth shallower than the first depth. A first injectant of a first type and a second injectant of a second type injected into the water-bearing zone through the first injection well and the second injection well, respectively.The second injectant is injected to sweep hydrocarbons in the hydrocarbon-bearing zone toward the production well. The first injectant is injected to sweep the second injectant toward the hydrocarbon-bearing zone. At least a portion of the hydrocarbons are produced through the production well.
Patent CA-3137101-A1 (CA)
Inventor: PATIL SIDDHESH D
IPC: C07K16/18
Filed: 2020-04-17
Abstract: L'invention concerne des préparations pharmaceutiques contenant des immunoglobulines hypersialylées. Les préparations sont stables vis-à-vis d'une contrainte de cisaillement. Les compositions pharmaceutiques décrites ici fournissent des compositions hslgG pharmaceutiquement acceptables qui sont stables vis-à-vis d'une contrainte de cisaillement, par exemple, un nombre important de particules subvisibles ne se forme pas lorsque la formulation est soumise à une contrainte de cisaillement, telle que l'agitation, par exemple pendant le transport, et la formulation peut ainsi être transportée et manipulée sous forme liquide.