baber/WOPTO huggingface dataset:
Patent MX-2022003537-A (MX)
Title: Combination therapies.
Inventor: CHRISTENSEN JAMES GAIL
IPC: A61K31/519
Filed: 2020-09-23
Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a an agent that blocks Programmed Death-1 receptor (PD-1) and Programmed Death Ligand-1 (PD -L1) signaling and a KRAS G12C inhibitor of Formula (I), Formula I- A or Formula I-B, kits comprising the compositions and methods of use therefor.
Patent MX-2022004220-A (MX)
Title: Recombinant live immunogenic composition comprising newcastle disease virus (ndv) expressing the s1 subunit and the rbd of the spike protein of sars-cov-2.
Inventor: FERNANDEZ DIAZ MANOLO CLEMENTE
IPC: A61K39/215
Filed: 2022-01-04
Abstract: The present invention relates to the obtainment of two live recombinant or vectored NDV vaccines expressing the S1 subunit and the RBD of the S protein of SARS-CoV-2 which, when applied intranasally in a hamster animal model, generate the production of neutralising antibodies against SARS-CoV-2. The invention also shows that these live vaccines are compatible for combined use with each other to induce the production of neutralising antibodies against SARS-CoV-2 without substantial cross-interference, indicating a synergy between the two vaccines, wherein recombinant NDV viruses (rNDV-LS1-HN-RBD/SARS-CoV-2 (SEQ ID No. 7) and rNDV-LS1-S1-F/SARS-CoV-2 (SEQ ID No. 13) express the S1 subunit and the RBD of the S protein of SARS-CoV-2 in mammals.
Patent MX-2022006483-A (MX)
Title: Aerosol provision system.
Inventor: FALLON GARY
IPC: A24F40/50
Filed: 2020-11-27
Abstract: There is provided an aerosol provision system comprising a power source; an aerosol generating component; and, control circuitry, wherein the control circuitry is arranged to control the power source and the aerosol generating component to provide a selection between at least: a predetermined aerosolisation profile; and a variable aerosolisation period, to be applied to aerosol generating material.
Patent MX-2022008632-A (MX)
Title: Ccr5 binding agent for treatment of ccr5 positive metastatic cancer.
Inventor: KELLY SCOTT
IPC: C07K14/705
Filed: 2021-01-13
Abstract: The present disclosure relates to the use of CCR5 binding agents, such as the leronlimab, in the treatment or prevention of CCR5+ metastatic cancer. Presented herein are methods for treating a subject for metastatic breast cancer by administering to the subject an effective amount of a CCR5 binding agent, such as leronlimab.
Patent MX-2022009750-A (MX)
Title: Routing communication in telecommunications network having multiple service communication proxies.
Inventor: LI PENG
IPC: H04L45/02
Filed: 2021-02-10
Abstract: A function in a network node in a telecommunications network having at least one service communication proxy, SCP, deployed between a first network node and a second network node performs a method including receiving a request for routing information to signal a message from the first network node to the second network node. The method further includes responsive to the request from the first network node, providing a response to a network node that sent the request wherein the response identifies at least a portion of a routing path for the message based on a routing path configuration.
Patent MX-2022011539-A (MX)
Title: Method for producing serum composition for preventing or treating mucosa-related infectious disease in young mammals, serum composition produced thereby, and use thereof.
Inventor: AHN BYUNG CHUL
IPC: A61K35/16
Filed: 2020-11-13
Abstract: The present invention relates to a method for producing a serum including protective antibodies having mucosal immunity which can protect against infection by mucosa-related infectious pathogens, the method comprising a step for administering mucosa-related infectious pathogens to mature swine and bovine via a mucosal route to induce, from the mature swine and bovine, the production of protective antibodies having mucosal immunity which can protect against infection by mucosa-related infectious pathogens; and a method for protecting young piglets and calves from infection by infectious pathogens, or treating young piglets and calves infected thereby, by administering the serum produced by the method to newborn or young piglets and calves. Infection of young piglets and calves by mucosa-related infectious pathogens can be prevented and treated by the method according to the present invention.
Patent MX-PA00002652-A (MX)
Title: Solvent-resistant microporous polybenzimidazole membranes.
Inventor: ROBERT P BARSS
IPC: B01D69/04
Filed: 2000-03-16
Abstract: Solvent-resistant polybenzimidazole membranes, methods of making them and crosslinking them and composite membranes and hollow fiber membrane modules from them are disclosed.
Patent MX-PA01001304-A (MX)
Title: Infinitely variable epicyclic transmissions.
Inventor: VAUGHN MARK R
IPC: F16H9/26
Filed: 1999-08-05
Abstract: An infinite variable transmission with input shaft (52), planetary carrier (28), planetary pulleys (36) and planetary gears (32) with planetary axles (30) equiangularly disposed on the carrier (28). Variable pitch pulley (41) adjust a serpentine belt (38) which adjust the rotation of the planetary gears (32) to adjust the output shaft (20).
Patent MX-PA01006213-A (MX)
Title: Position sensor and circuit for optical encoder.
Inventor: ALESSANDRO MORTARA
IPC: G06G7/19
Filed: 1999-11-17
Abstract: An electronic circuit for measuring the position of a spatially periodic intensity pattern of incident radiation includes an array of detectors (1); two or more correlator units (2, 3) each having arrays of capacitors (12, 13) connected to a buffer (14); and a phase angle computing unit (4). The pitch of the array of detectors (1) is smaller than the pitch of the incident intensity pattern so that the latter is oversampled, yielding high accuracy. The detector outputs (17) are weighted by respective fixed capacitance values (15, 16) which vary periodically along arrays of capacitors (12, 13), and a weighted sum of outputs for each correlator unit (2, 3) is output at its respective buffer (14). The capacitance values (15, 16) of respective correlator units (2, 3) are mutually offset by a predetermined phase shift. The analog computation using capacitor arrays (12, 13) is fast and energy efficient, and can be implemented as a VLSI circuit.
Patent MX-PA01006512-A (MX)
Title: Piezoelectric micropump.
Inventor: PETERS RICHARD D
IPC: F04B9/00
Filed: 1999-12-21
Abstract: A piezoelectric micropump (10) is disclosed for pumping fluid from a container (14) to a delivery point in low volumes and at controlled flow rates. The pumping action is created by movement of two or three diaphragms (40, 42, 44). The movement of each diaphragm is caused by expansion and contraction of an attached piezoelectric actuator (46, 48, 50). Coordination of the movement of the diaphragms (40, 42, 44) creates unidirectional flow of the fluid. The piezoelectric actuators (46, 48, 50) are cantilevered between the pump body (22) and the diaphragms (40, 42, 44) to provide greater deflection of the diaphragms (40, 42, 44). The piezoelectric actuators (46, 48, 50) preferably are piezoelectric bimorphs such that the diaphragms (40, 42, 44) can function as both seals and pumps.
Patent MX-PA01009605-A (MX)
Title: Retracted pocket spring mattress; method for manufacturing of a pocket spring mattress and device for pre-tensioning pocketed coil springs.
Inventor: EDLING KENNETH
IPC: A47C27/06
Filed: 2000-03-24
Abstract: The present invention relates to a spring mattress comprising springs enclosed in casings, a so-called pocket mattress, and a method and a device for manufacturing such a mattress. The spring mattress according to the invention comprises a plurality of interconnected coil springs (1) enclosed in casings (2), for at least one of the springs, the casing portions arranged at the spring ends being moved towards each other, through the spring, and interconnected with the aid of connecting means.
Patent MX-PA02000149-A (MX)
Title: High molecular weight zwitterionic polymers.
Inventor: CARTER PHILLIP W
IPC: C08F226/10
Filed: 2000-06-28
Abstract: This invention is directed to high molecular weight water-soluble zwitterionic polymers derived from zwitterionic and nonionic monomer units, and to the use of the polymers in papermaking processes.
Patent MX-PA02001709-A (MX)
Title: Fused pyrrolecarboxamides: gaba brain receptor ligands.
Inventor: KENNETH SHAW
IPC: C07D417/14
Filed: 2000-08-30
Abstract: Substituted pyrrolecarboxamide compounds are disclosed. These compounds are highly selective agonists, antagonists or inverse agonists for GABAA brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAA brain receptors and are therefore useful in the diagnosis and treatment of anxiety, depression, Alzheimers dementia, sleep and seizure disorders, overdose with benzodiazepine drugs and for enhancement of memory. Pharmaceutical compositions, including packaged pharmaceutical compositions, are further provided. Compounds of the invention are also useful as probes for the localization of GABAA receptors in tissue samples.
Patent MX-PA02002070-A (MX)
Title: Method for evaluating dynamic perspective distortion of transparent body and method for supporting designing of three-dimensional shape of transparent body.
Inventor: YAJIMA TATSUO
IPC: G06T15/20
Filed: 2001-06-26
Abstract: A method comprising the steps of creating a three-dimensional curved surface geometric model of a transparent body, determining an eye point and a virtual evaluation pattern, viewing the virtual evaluation pattern through the transparent body from the eye point so as to determine the intervals between adjacent perspective evaluation points, determining one of the intervals as a reference value, and calculating the ratio of each interval to the reference value so as to evaluate the dynamic perspective distortion of the transparent body.
Patent MX-PA02002478-A (MX)
Title: Novel uses of mammalian ccr6 receptors and related reagents.
Inventor: COOK DONALD
IPC: A61P25/28
Filed: 2000-09-07
Abstract: Compositions and methods for using mammalian CCR6 and MIP 3agr; proteins to treat an abnormal physiological condition in an individual. The methods comprise administering a therapeutically effective amount of CCR6 or MIP 3agr; alone, or in combination with other therapeutic reagents; or a CCR6 or MIP 3agr; antagonist. Genetically engineered animals and their use as models of molecular mechanism are also provided.
Patent MX-PA02008884-A (MX)
Title: Method for regulating a roasting furnace.
Inventor: SIIRILAE HEIKKI
IPC: C22B1/10
Filed: 2001-03-16
Abstract: The invention relates to a method of regulating a roasting furnace in fluidized bed roasting. Part of the roasting furnace grate is separated off into a separate grate section, known as the overflow grate, where the nozzles and the amount of roasting gas blown through them can be regulated independently of the main grate. It is advantageous to position the separately regulated grate in the section of the furnace where the overflow aperture is located.
Patent MX-PA02011352-A (MX)
Title: Novel benzofuran derivatives.
Inventor: TAKADA TAKEKO
IPC: C07D405/14
Filed: 2001-05-18
Abstract: The invention relates to novel benzofuran derivatives of the general formula (I) or salts thereof (wherein Py is 2 , 3 , or 4 pyridyl; and R is substituted or unsubstituted phenyl or a substituted or unsubstituted aromatic heterocyclic group). The invention also relates to inhibitors against steroid 17 agr; hydroxylase and or C17 20 lyase or pharmaceutical compositions which contain the derivatives (I) or the salts.
Patent MX-PA03000014-A (MX)
Title: Methods for using tetanus toxin for benificial purposes in animals (mammals).
Inventor: SANDERS IRA
IPC: A61P25/06
Filed: 2001-06-28
Abstract: Methods of using tetanus toxin to modulate or control neural functions or nonneural cellular activities at selected sites in animals, particularly in mammals, and more particularly in humans, are provided. Pharmaceutical formulations to modulate neural functions or non-neural cellular activities of an animal at selected sites in animals, particularly in mammals, and more particularly in humans are also provided. Uses of tetanus toxin in preparation of medicaments for methods of treating clinical disorders or symptoms of animals, particularly mammals and more particularly humans are also provided.
Patent MX-PA03000320-A (MX)
Title: A catalyst support, a supported group viii metal catalyst and a precursor thereof, processes for their preparation, and a use of the supported group viii metal catalyst.
Inventor: HUISMAN HANS MICHIEL
IPC: B01J23/889
Filed: 2001-07-10
Abstract: A process for preparing a catalyst support or a supported Group VIII metal catalyst or a precursor of the supported Group VIII metal catalyst, which process comprises (a) exerting mechanical power on a mixture comprising a refractory oxide and a first liquid to obtain a dough, (b) admixing the dough with a second liquid to obtain a slurry, (c) shaping and drying the slurry, and (d) calcining.
Patent MX-PA03008227-A (MX)
Title: Aerated food component.
Inventor: KEPPLINGER JOHN
IPC: A23L29/231
Filed: 2002-03-13
Abstract: An aerated food component is disclosed. The aerated food component is formed from a mixture of sweeteners, a fruit concentrate, an ionic hydrocolloid, a calcium source, an edible acid, a cation source, and a whipping protein. Also disclosed is a method for forming the aerated food component. The aerated food component can be used as a semi-moist fruit supplement in a variety of consumer food products. Alternatively, the aerated food component can be extruded, cut into pieces and dried to form a low moisture aerated cereal additive that remains crisp in a liquid. The disclosed formulation also permits high levels of fruit to be incorporated into the aerated food component.
Patent MX-PA03009675-A (MX)
Title: Apparatus for conditioning air.
Inventor: MORDECHAI FORKOSH
IPC: F24F3/153
Filed: 2001-04-23
Abstract: providing a liquid desiccant (20) at a first location (18); removing moisture from the liquid desiccant at the first location to a first source of air (22, 24); providing liquid desiccant (20') at a second location (18'), said liquid desiccant at said second location (18') being in fluid communication with the liquid desiccant at the first location (18); absorbing moisture by the liquid desiccant at the second location from a second source of air (22', 24'); and transferring moisture from the first location (18) to the second location (18') substantially only by diffusion and gravity.
Patent MX-PA03009844-A (MX)
Title: Polypropylene preparation.
Inventor: SANDOR NAGY
IPC: C08F4/659
Filed: 2002-04-25
Abstract: A propylene polymerization process is disclosed. The process gives polypropylene having isotactic and atactic stereoblock sequences. The process is performed in the presence of a non-bridged bisindenoindol-based single-site catalyst. The polypropylene produced has an isotactic pentad (mmmm) content within the range of about 10 mole % to about 70 mole %.
Patent MX-PA03011258-A (MX)
Title: Pulp and synthetic fiber absorbent composites for personal care products.
Inventor: CHARLES WILSON COLMAN
IPC: B32B5/22
Filed: 2002-06-25
Abstract: There is provided a personal care product that has a liquid impermeable backsheet, a liquid permeable topsheet, and an absorbent composite located between the topsheet and backsheet. The absorbent composite has an upper layer made of synthetic fiber with at most 20 weight percent pulp and the upper layer has a density between about 0.03 and 0.15 g/cc and a basis weight between about 20 to 75 gsm. The composite has a lower layer having from 80 to 95 weight percent pulp, at most 20 weight percent binder, and has a density greater than the upper layer and between 0.06 and 0.20 g/cc, and a basis weight between 120 and 200 gsm.
Patent MX-PA04003461-A (MX)
Title: Method of obtaining 2-(2-nitrovinyl)-furan and the use thereof as a coccidiostatic.
Inventor: AMALIA CALVO ALONSO
IPC: C07B61/00
Filed: 2002-09-24
Abstract: The invention relates to a method of obtaining and purifying 2-(2-nitrovinyl)furane consisting in reacting furfural and nitromethane, using isobutylamine as a catalyst and activated carbon as an adsorbent, in order to obtain a product of pharmaceutical quality. Said technique considerably reduces the environmental impact by eliminating the gaseous waste from the system by means of absorption in water. The inventive pharmaceutical composition contains 2-(2-nitrovinyl)furan and has powerful action against low concentrations of coccidia.
Patent MX-PA04006025-A (MX)
Title: Formulation & dosage form for the controlled delivery of therapeutic agents.
Inventor: NGUYEN VU A
IPC: A61K9/22
Filed: 2002-12-19
Abstract: The present invention includes a formulation and controlled release dosage form that enable the controlled release of therapeutic agents showing reduced absorption in the lower gastrointestinal tract. The formulation of the present invention includes a therapeutic agent that exhibits greater absorption in the upper GI tract than in the lower GI tract and a permeation enhancer, which serves to increase absorption of the therapeutic agent in the lower GI tract. The formulation of the present invention further includes a carrier that allows the formulation to transition to a bioadhesive gel in situ after the formulation is dispensed within the GI tract and has had some opportunity to reach the surface of the GI mucosal membrane. The bioadhesive gel formed by the formulation of the present invention works to present effective concentrations of both the therapeutic agent and the permeation enhancer at the surface of the GI mucosal membrane over a period. The controlled release dosage form of the present invention is designed to deliver the formulation of the present invention at a desired release rate or release rate profile over a desired period of time.
Patent MX-PA04008314-A (MX)
Title: O-cyclopropyl-carboxanilides and their use as fungicides.
Inventor: HANS TOBLER
IPC: A01N43/78
Filed: 2003-02-21
Abstract: F1 Het is a 5- or 6-membered heterocyclic ring containing one to three heteroatoms, each independently selected from oxygen, nitrogen and sulphur, the ring being substituted by groups R4, R5 and R6; R1 is hydrogen or halo; R2 is hydrogen or halo; R3 is optionally substituted C2-12 alkyl, optionally substituted C2-12 alkenyl, optionally substituted C2-12 alkynyl, optionally substituted C3-12 cycloalkyl, optionally substituted phenyl or optionally substituted heterocyclyl; and R4, R5 and R6 are, independently, selected from hydrogen, halo, cyano, nitro, C1-4 haloalkyl, C1-4 alkoxyl (C(1-4) alkoxyl (C1-4) alkyl and C1-4 haloalkoxy (C1-4) alkyl, provided that at least one of R4, R5 and R6 is not hydrogen. The compounds of formula (I) have plant-protective properties and are suitable for protecting plants against infestations by phytopathogenic microorganisms.
Patent MX-PA04008427-A (MX)
Title: Audio frequency scaling during video trick modes utilizing digital signal processing.
Inventor: ROBERT WARREN SCHMIDT
IPC: H04N7/16
Filed: 2003-02-19
Abstract: The invention concerns a method and apparatus for audio track playback during fast forward playback video trick modes. A storage medium reader (100) is provided for reading digital data from a storage medium such as a DVD (300) (102). The digital data represents a video presentation and a corresponding audio programming. A decoder (182) decodes from a portion of the digital data comprising the audio programming a plurality of digital audio samples (345) corresponding to a selected portion of the video presentation. Subsequently, a digital signal processor (186) can convert the audio samples to their corresponding frequency domain equivalents (330) and scale the frequency and amplitude of a playback audio frequency (335) associated with the audio samples in accordance with trick mode video playback.
Patent MX-PA04012093-A (MX)
Title: Diphenyl azetidinones substituted by acidic groups, method for their production, medicaments containing said compounds and use thereof.
Inventor: STEFANIE FLOHR
IPC: A61P5/50
Filed: 2003-06-04
Abstract: The invention relates to compounds of formula (I), in which R1, R2, R3, R4, R5 and R6 are defined as cited, in addition to their physiologically compatible salts. The compounds are suitable for use e.g. as hypolipidaemics.
Patent MX-PA04012405-A (MX)
Title: Compressed resin moderated chewing gum.
Inventor: DORTHE BOESEN SCHACKINGER
IPC: A23G4/20
Filed: 2003-07-02
Abstract: The invention relates to a compressed chewing gum tablet and gum base granule for such tablet comprising at least one elastomer in an amount of about 0% to about 35% by weight of the gum base, at least two resins in an amount of about 15% to about 60% by weight of the gum base, gum base ingredients and where said at least two resins comprising- natural resin in an amount of about 5% to about 40% by weight of the gum base; -synthetic resin in amount of about 10% to about 40% by weight of the gum base.
Patent MX-PA05000805-A (MX)
Title: Hopper closure assembly and method of using same.
Inventor: HELDER LEON J
IPC: B65D90/54
Filed: 2005-01-19
Abstract: A closure mechanism for a hopper bottom trailer which utilizes potential a nd kinetic energy of granular material in the hopper. The hopper closure assemb ly may have an angled member upon a gate that translates kinetic energy for moving granular material into longitudinal movement of the gate. The hopper closure assembly may have a raising structure which lifts the gate relative to the gate frame to create potentia l energy to assist in movement of the gate down the raising structure and in opening the discharge opening of the hopper. A method of using a hopper closure assembly which involves the steps opening the discharge opening by moving the gate longitudinally, also including the steps permitting the granular material to assist in opening the gate by striking t he angled member, and additionally permitting the leading edge to move from the receiving member of the gate frame by descent from the raising structure.
Patent MX-PA05002407-A (MX)
Title: Flexible molded parts of expanded polyurethane and their use.
Inventor: PFEUFFER UWE
IPC: C08G101/00
Filed: 2005-03-02
Abstract: The invention relates to flexible molded parts of expanded polyurethane with molded part densities of <350 KG/M<SUP>3 </SUP>and with a thick skin on one side and good molded part stability (molded part shrinkage <1.5%; according to DIN ISO 02769) based on special components, and their use, especially in the shoe sector.
Patent MX-PA05002887-A (MX)
Title: Pyrazolo[3,4-b]pyridine compounds, and their use as phosphodiesterase inhibitors.
Inventor: WARD PETER
IPC: A61P29/00
Filed: 2003-09-12
Abstract: The invention relates to a compound of formula (I) or a salt thereof: wherein:R1 is C1-4alkyl, C1-3fluoroalkyl, -CH2CH2OH or -CH2CH2CO2C1-2alkyl;R2 is a hydrogen atom (H), methyl or C1fluoroalkyl;R3 is optionally substituted C3-8cycloalkyl or optionally substituted mono-unsaturated-C5-7cycloalkenyl or an optionally substituted heterocyclic group of sub-formula (aa), (bb) or (cc); in which n1 and n2 independently are 1 or 2; and in which Y is O, S, SO2, or NR10; or R3 is a bicyclic group (dd) or (ee): ; and wherein X is NR4R5 or OR5a. The compounds are phosphodiesterase (PDE) inhibitors, in particular PDE4 inhibitors. Also provided is the use of a compound of formula (I), or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the treatment and/or prophylaxis of an inflammatory and/or allergic disease in a mammal such as a human, for example chronic obstructive pulmonary disease (COPD), asthma, or allergic rhinitis.