baber/WOPTO huggingface dataset:
Patent ES-2254683-T3 (ES)
Title: Utilizacion de derivados de piridoindolona para la preparacion de medicamentos anticancerigenos.
Inventor: BOURRIE BERNARD
IPC: A61K45/00
Filed: 2002-04-26
Granted: 2006-06-16
Abstract: Utilización de un compuesto de fórmula: en la que: - R1 representa un átomo de hidrógeno o un grupo metilo o etilo; - R2 representa un grupo metilo o etilo; o bien - R1 y R2 forman juntos un grupo (CH2)3 ; - r3 representa, bien un grupo fenilo opcionalmente sustituido con un átomo de halógeno o un grupo metilo o metoxi, o bien un grupo tienilo ; - R4 representa un átomo de hidrógeno o de cloro o un grupo metilo o metoxi ; para la preparación de medicamentos útiles como agentes anticancerígenos.
Patent ES-2274047-T3 (ES)
Inventor: HAYTER BARRY RAYMOND
IPC: A61K31/5377
Filed: 2002-06-24
Granted: 2007-05-16
Abstract: The invention related to novel compounds of Formula (I) or a salt, solvate or prodrug thereof, wherein A, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, n and m are as described in the specification, useful in the treatment of a disease or condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relates to methods for preparing compounds of Formula (I) and their use as medicaments in the treatment of diseases mediated by glucokinase.
Patent ES-2367299-T3 (ES)
Inventor: HOLMES WILLIAM
IPC: F16L25/00
Filed: 2002-11-22
Granted: 2011-11-02
Abstract: A locking segment for use in connecting two lengths of pipe has a radically extending heel that serves as a rotational brake. By mating the brake into an annular trough, that is, by placing it between two walls, the rotation of the segment can continue only until points on the brake mure between the two walls. Rotation of the segment in response to increasing thrust pressures can thereby be arrested before the rotation causes the segment to bear on the spigot with a radially inward force great enough to penetrate the spigot.
Patent ES-2250728-T3 (ES)
Inventor: DRENT EIT
IPC: C08G69/16
Filed: 2002-11-05
Granted: 2006-04-16
Abstract: Bidentate ligand of formula (I), R<SUP>1</SUP>R<SUP>2</SUP>M<SUP>1</SUP>-R-M<SUP>2</SUP>R<SUP>3</SUP>R<SUP>4 </SUP>wherein M<SUP>1 </SUP>and M<SUP>2 </SUP>each indenpendently represent P, As or Sb; R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3 </SUP>and R<SUP>4 </SUP>each independently represent the same or a different optionally substituted organic group and at least one of R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3 </SUP>and R<SUP>4 </SUP>contains a tertiary carbon atom through which the group is linked to M<SUP>1 </SUP>or M<SUP>2</SUP>; and R represents a bridging group based on a trimethylene group connecting M<SUP>1 </SUP>and M<SUP>2 </SUP>of which the middle carbon atom is double bonded to a non-metal element chosen from group 14, 15 or 16 of the periodic table of elements. Catalyst comprising this bidentate ligand and carbonylation process n which this catalyst is used.
Patent ES-2310615-T3 (ES)
Inventor: DOW ELEANOR
IPC: C12Q1/6886
Filed: 2002-12-24
Granted: 2009-01-16
Abstract: The present invention provides a method of detecting non-apoptotic DNA in clinical samples. In particular there is provided a novel screening methodology for the detection of colorectal carcinoma. Cancer results from genetic mutations which result in uncontrolled and unregulated cell growth. Apoptosis does not occur in cancerous cells and thus the DNA remains unfragmented. Colorectal cancer results from mutations which occur in varying sites of the DNA. Accordingly there is no ubiquitous marker specific to colorectal tumour cells. The present invention provides the finding that the presence of specific fragments of DNA can be used to diagnose cancer irrespective of the point of DNA mutation. The method includes the step of obtaining a suitable sample, extracting the DNA therefrom and then amplifying and separating the fragments by electrophoresis in order to detect the presence of banding which is indicative of non-fragmented DNA derived from cancerous cells.
Patent ES-2261803-T3 (ES)
Inventor: ALGUERA GALLEGO JOSE
IPC: B62D53/08
Filed: 2003-02-21
Granted: 2006-11-16
Abstract: The saddle coupling between a tractor vehicle and boom has a connecting plate and a bearing trunnion (2) fixed to the vehicle frame. The connecting plate can pivot with respect to the trunnion and has a pair of cylindrical bearing cavities to receive a corresponding bearing surface (8) on the trunnion. The trunnion is made of a one piece casting with a vertical mounting face (13) for direct attachment to a vehicle longitudinal beam.
Patent ES-2240876-T3 (ES)
Title: Travesaño entre dos zonas de borde laterales de una estructura de vehiculo.
Inventor: SCHEER JURGEN
IPC: B62D29/00
Filed: 2003-03-20
Granted: 2005-10-16
Abstract: Travesaño entre dos zonas de borde laterales de una estructura de vehículo con al menos un elemento de sujeción para amarrar elementos funcionales del vehículo, caracterizado porque el travesaño (1) está constituido axialmente por un primer tramo (2) de acero y un segundo tramo (3) de un metal ligero que están soldados uno con otro.
Patent ES-2277627-T3 (ES)
Title: Preparacion de quinazolinonas fungicidas e intermediarios utiles.
Inventor: BEREZNAK JAMES FRANCIS
IPC: C07C271/68
Filed: 1997-06-12
Granted: 2007-07-16
Abstract: Un proceso para la preparación de a quinazolinona de Fórmula I donde R1 es alquilo C1-C10; alquenilo C3-C10; cicloalquilo C3-C10; halocicloalquilo C3-C10; cicloalquilalquilo C4-C10 ; halocicloalquilalquilo C4-C10 ; o alquinilo C3-C10; R2 es alquilo C1-C10; alquenilo C3-C10; cicloalquilo C3-C10; halocicloalquilo C3-C10; cicloalquilalquilo C4-C10 ; halocicloalquilalquilo C4-C10 ; cicloalquilo C4-C10; halocicloalquilo C4-C10; o alquinilo C3-C10; y R3 y R4 son cada uno de forma independiente hidrógeno o halógeno; de los compuestos que contienen el motivo IIg que se caracteriza por emplear una secuencia de proceso que comprende el tratamiento de un ácido o éster antranílico de Fórmula 1b donde R6 es hidrógeno o un alquilo C1-C6 con un compuesto de Fórmula III donde A es Cl o S(alquilo C1-C6) opcionalmente en presencia de un ácido o una base, y un disolvente inerte a una temperatura de desde 0 a 100ºC, y a una presión de desde 1 a 5 atmósferas.
Patent ES-2391526-T3 (ES)
Title: Encendedor de mano
Inventor: LEI HOU CHONG
IPC: F23Q2/16
Filed: 2003-06-12
Granted: 2012-11-27
Abstract: Encendedor de mano (1), que comprende:un recipiente de combustible (2),una válvula de combustible (4, 7) para permitir que el combustible se suministre desde el recipiente de combustible(2) a un punto de ignición (5),una palanca (6) para abrir la válvula de combustible (4, 7),una rueda de chispas (9) montada de manera giratoria en contacto con la piedra (10), de modo que cuando la ruedade chispas gira, se generan chispas mediante la piedra y se proyectan al punto de ignición (5), en el que hay almenos una rueda lateral (12, 13), montada de manera giratoria respecto a la rueda de chispas (9), adyacente a larueda de chispas, teniendo la rueda lateral una superficie operativa (19) para acoplarse a un pulgar o un dedo de unusuario para hacer girar la rueda lateral, estando configurada la rueda lateral para hacer girar la rueda de chispas através del contacto de fricción entre una primera superficie anular de fricción (18) de la por lo menos una ruedalateral y una segunda superficie de fricción circunferencial (19) formada en el borde exterior de la rueda de chispas ysituada dentro de la superficie anular de la por lo menos una rueda lateral,estando montada la por lo menos una rueda lateral sobre un eje (14, 15), estando montado el primer extremo del ejeen un cojinete y sobresaliendo un segundo extremo del eje en un cojinete de la rueda de chispas, caracterizadoporque la longitud axial de la por lo menos una rueda lateral (12, 13) está en el intervalo de 0,5 a 1,5 veces lalongitud axial de la rueda de chispas (9).
Patent ES-2278125-T3 (ES)
Title: Procedimiento de acceso a un servicio a traves de una red de telefonia movil que tiene en cuenta la calidad de la conexion "datos".
Inventor: FOURNIER JEAN-PHILIPPE
IPC: H04M1/72445
Filed: 2003-09-25
Granted: 2007-08-01
Abstract: Procedimiento de acceso a un servicio a través de una red de telefonía móvil (10), según el cual se entran unas instrucciones por medio de un teléfono móvil (50) y se transmiten las instrucciones por un canal datos de la red de telefonía móvil (10) hacia un servidor (20), siendo un dispositivo de reconocimiento vocal (40) apto para interpretar las instrucciones y siendo el servidor (20) apto para efectuar un trabajo en función de esta interpretación, caracterizado porque se mide un parámetro relativo a la calidad de la transmisión del canal datos de la red (10), y porque: - en el caso en que el parámetro de calidad es superior a un cierto umbral, se hace pasar al teléfono (50) a un modo de funcionamiento según el cual es apto para tomar en cuenta unas instrucciones en forma vocal y para convertirlas en datos para transmitirlas al servidor (20), - en el caso en que el parámetro de calidad es inferior al umbral, se hace pasar el teléfono (50) al modo de funcionamiento según el cual se entranlas instrucciones en forma gráfica y se transmiten las instrucciones al servidor (20).
Patent ES-2272956-T3 (ES)
Inventor: BERGHAUS GERD
IPC: B21D41/00
Filed: 2003-03-17
Granted: 2007-05-01
Abstract: The present invention relates to a device for the deformation of workpieces, in particular for the plastic shaping of pipe ends, with a shaping unit actuated by the pressure of a fluid and with a prestressing unit arranged on a common longitudinal axis and actuated by the pressure of a fluid and also with clamping elements of conical design which can be clamped by means of the prestressing unit, in each case at least one separate pressure space being designed in the shaping unit and in the prestressing unit, which space can be pressurized independently of the pressure space of the other unit in each case. In this connection, the shaping unit and the prestressing unit are interconnected but completely closed off in relation to one another.
Patent ES-2266795-T3 (ES)
Inventor: POLTI FRANCO
IPC: A47L11/34
Filed: 2003-02-19
Granted: 2007-03-01
Abstract: The present invention relates to a handgrip for a nozzle for fluids, in particular for hot fluids and/or liquids under pressure, of the type comprising a body (7) provided with an intake/outlet element (4) and the operating member (11), and having the particular characteristic that an appendage (8) extends from the body and has a portion (8a) of its surface disposed above the tube (5), the apendage (8) being the seat for the operating member (11), and that the operating member (11) is positioned in the surface portion (8a) of the appendage (8) in a manner such as to be arranged facing the at least one tube (5).
Patent ES-2357057-T3 (ES)
Inventor: MARTIN NIALL MORRISON BARR
IPC: C07D237/32
Filed: 2003-04-29
Granted: 2011-04-15
Abstract: A compound of formula:
Patent ES-2372931-T3 (ES)
Inventor: BEZENCON OLIVIER
IPC: A61P15/10
Filed: 2003-04-08
Granted: 2012-01-27
Abstract: The invention relates to novel 3,9-diazabicyclo[3.3.1]nonene derivatives of formula (I) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors or renin.
Patent ES-2265110-T3 (ES)
Inventor: BISHOP PETER
IPC: B60N2/06
Filed: 2003-02-12
Granted: 2007-02-01
Abstract: To allow for optimum arrangement of the rows of seats for any individual flight, the distance between rows is adjusted in the longitudinal direction of the passenger plane, optionally according to sections, by storing in a control device an actually desired arrangement of rows, and automatically displacing (via the control device) every row whose position has to be changed to achieve the actually desired arrangement of rows on its fastening rails to the position determined by the actually desired arrangement of rows. In this way, it is possible to provide a passenger plane, preferably prior to landing, with the data of the actual passenger distribution and the resulting optimum arrangement of rows for the next flight so that it can be prepared after landing for the next flight in the shortest possible time.
Patent ES-2687644-T3 (ES)
Title: Procedimiento de procesamiento de una imagen adquirida por medio de una guía compuesta por una pluralidad de fibras ópticas
Inventor: PERCHANT AYMERIC
IPC: G06T5/00
Filed: 2003-07-11
Granted: 2018-10-26
Abstract: Procedimiento de procesamiento de imagen adquirida por medio de una guía constituida por una pluralidad de fibras ópticas, que incluye las siguientes etapas: para cada fibra óptica, - se aísla en la imagen adquirida una zona correspondiente a esa fibra óptica aplicando una máscara correspondiente al motivo de la pluralidad de fibras ópticas, correspondiendo dicha máscara, además, a una imagen de las componentes conexas que representan cada fibra y obteniéndose a lo largo de una etapa de detección de las fibras a partir de una imagen testigo; - se procesa localmente cada zona de manera individual realizando las dos siguientes etapas: - cálculo del flujo detectado dentro de cada zona de la imagen adquirida, - cálculo del flujo detectado dentro de cada zona de un conjunto de imágenes de referencia que incluyen una imagen de fondo parásita y una imagen de calibración, y luego - se gradúa el flujo de la imagen adquirida a partir de los flujos de las imágenes de referencia, y luego - se reconstruye la imagen adquirida eliminando el motivo debido a las fibras ópticas; caracterizado por que dicha etapa de detección de las fibras comprende las siguientes etapas: - prefiltrado de la imagen testigo, - segmentación por región, - corrección de segmentos que presentan una superficie anormalmente grande, y corrección de segmentos que presentan una superficie anormalmente pequeña, y por que la corrección de segmentos comprende las siguientes etapas: - selección de los segmentos anormalmente grandes y que tienen demasiados vecinos con respecto a una superficie normal de las fibras; - resegmentación con una cuenca, bien en la imagen primitiva, o bien en una imagen de mapa de distancia en el interior de los segmentos detectados; - cálculo del grafo de adyacencia de los segmentos anormalmente pequeños, antes de decidir qué fibras se tienen que fusionar obligatoriamente, con cada vecina, y aquellas que solo son candidatas.
Patent ES-2291674-T3 (ES)
Inventor: DE NORA VITTORIO
IPC: C25C3/08
Filed: 2003-06-03
Granted: 2008-03-01
Abstract: A cell for the electrowinning of aluminium by the electrolysis from an aluminium compound dissolved in a molten electrolyte (50), comprises: (I) a plurality of non-carbon anodes (10), each anode being suspended in operating in the molten electrolyte by an anode stem (11) that connects the anode (10) to a positive current source; and (II) a thermic insulating cover (60,60′) which covers the electrolyte (50) and through which each anode stem (11) extends from the positive current source to an anode (10). The insulating cover (60,60′) comprises a plurality of movable sections (60) that together cover a substantial part of the electrolyte (50). Each movable section (60) covers a corresponding portion of the electrolyte (50) that is located therebelow and that can be uncovered by moving the corresponding movable section (60). The anode stem (11) of each anode (10) extends through the insulating cover (60,60′) between two movable sections (60) or between a movable section (60) and a fixed section (60′) of the insulating cover (60,60′) when the sections (60) are in a covering position over the electrolyte (50). Each movable section (60) is movable to uncover the corresponding electrolyte portion without interrupting operation of any anode (10), for example by tilting, in particular pivoting, or sliding and/or lifting the section (60).
Patent ES-2309344-T3 (ES)
Inventor: PUIG I VILA JORDI
IPC: B41F27/10
Filed: 2003-10-08
Granted: 2008-12-16
Abstract: SUMARY   Comprises first and second pieces (10, 20) which have end configurations (11, 21) for installation and guide and respective coupling configurations (14, 24) plug-in fit at the ends of a third, tubular piece (30) which defines an intermediate, cylindrical section (31), for attachment of liners (40). The hydraulic device comprises two expansible sleeves (50) situated on the first and second pieces (10, 20) each with a circular cavity (51) connected to a longitudinal duct through the shaft containing a fluid capable of being subjected to pressure to make convex an external, deformable wall (52) of the sleeve. The longitudinal duct comprises first and second sections (12, 22) in the first and second pieces (10, 20) connected, by means of a flexible tube (60) located in the hollow interior of the third piece (30).
Patent ES-2283860-T3 (ES)
Inventor: KEITH RICHARD
IPC: A61K31/351
Filed: 2003-09-01
Granted: 2007-11-01
Abstract: Combinations of alpha7-nAChR agonists and statins, pharmaceutical compositions containing the same and methods of using the same useful for treatment or prophylaxis of neurological degenerative diseases.
Patent ES-2355097-T3 (ES)
Inventor: EISEN NORBERT DR
IPC: C08G18/30
Filed: 2004-12-06
Granted: 2011-03-22
Abstract: Production of a polyurethane integral foam involves reaction of an isocyanate component comprising (i) an optionally modified organic polyisocyanate and/or its pre-polymer and (ii) an inorganic zeolite with a specified polyol composition : Production of a polyurethane integral foam involves reaction of an isocyanate component comprising (i) an optionally modified organic polyisocyanate and/or its pre-polymer and (ii) an inorganic zeolite with a polyol composition comprising (A) a polyol of hydroxy number 20-1050 (especially 200-900) and functionality 2-6 (especially 2-5) and/or a mixture of polyols with calculated average OH number 250-650 (especially 350-500) and calculated average functionality 2.5-5 (especially 3-4.5); (B) water; and optionally (C) chain- extenders, crosslinkers, activators and/or conventional additives.
Patent ES-2298710-T3 (ES)
Inventor: DE DOMPIERRE JEAN-BERNARD
IPC: B31B50/04
Filed: 2004-10-15
Granted: 2008-05-16
Abstract: The method involves spacing front storage stoppers (3) of a receiving slide-frame to permit a passage of grippers (5a) of a gripper bar (5) between the stoppers. The bar is inclined around a cross shaft, to lower the grippers below respective upper edges of the stoppers, while simultaneously opening the grippers, to separate a full sheet from the grippers by bringing a front edge of the sheet against the stoppers. An independent claim is also included for a full sheet receiving station of a plate like components transformation machine.
Patent ES-2270342-T3 (ES)
Inventor: THOMANEK ERIK
IPC: B21B1/46
Filed: 2004-01-30
Granted: 2007-04-01
Abstract: A method for rolling thin and/or thick slabs made of steel materials into hot-rolled strip, which were previously cast as thin or thick slabs in a continuous casting machine, heated to rolling temperature in a pusher furnace or in a walking-beam furnace, and rolled in a common rolling train, then cooled and wound into coils. The method is carried out in a continuous manner at maximum capacity of the roughing train according to the quality standard of the hot-rolled strip while roller wear is reduced due to the fact that the roughing train is formed inline by roughing stands and finishing stands into which thin slab sections or thick slab sections are introduced at a suitable point of the roughing train according to the thickness thereof.
Patent ES-2336565-T3 (ES)
Title: Pastilla detergente mejorada y procedimiento de fabricacion.
Inventor: MHATRE SUBHASH SHIVSHANKAR
IPC: C11D17/00
Filed: 2004-03-19
Granted: 2010-04-14
Abstract: Un procedimiento para la fabricación de composiciones detergentes aireadas de forma sólida que comprende los pasos de: i) preparación de una masa fundida de la composición detergente que ha de moldearse; ii) adición del 0,1% al 10% en peso de alcohol graso a la masa fundida ya sea antes o después de que se haya incorporado a la masa fundida aire o gas; iii) mezclar la masa fundida en una mezcladora con cizalladura elevada; iv) verter la masa fundida en un molde; v) enfriar el molde; vi) desmoldear el artículo conformado solidificado.
Patent ES-2289521-T3 (ES)
Title: Tambor para lavadora y secadora.
Inventor: HAN IN HEE
IPC: B21D53/34
Filed: 2004-06-03
Granted: 2008-02-01
Abstract: Tambor (1) para una lavadora y una secadora, que comprende: una parte de un cuerpo cilíndrico de metal (100); partes reducidas (110) en los extremos opuestos de la parte del cuerpo, teniendo cada uno de ellas un diámetro menor que el diámetro de la parte del cuerpo; y partes dobladas (120) que tienen un borde plegado de la parte reducida.
Patent ES-2321619-T3 (ES)
Inventor: ZUMBE ALBERT
IPC: A23G1/00
Filed: 2004-07-09
Granted: 2009-06-09
Abstract: A process in which whole cocoa bean product, specifically a whole cocoa bean powder or liquor, is produced comprising the steps of subjecting the whole cocoa bean to a cleaning step in which the whole cocoa beans are passed through a cleaning machine that removes dried cocoa pulp, pieces of pod and other extraneous material to yield cleaned whole cocoa beans; pressing the whole cocoa beans to reduce the fat content to not more than 15wt% and to form a presscake and fat which is removed, subjecting the presscake to a particle size reduction step to obtain a bean intermediate whereby no more than 1vol% of the product has a particle size greater than or equal to 1cm; subjecting the bean intermediate to a microbicidal step to obtain a bean intermediate with a reduced microbiological content; subjecting the bean intermediate with reduced microbiological content to a drying step to reduce the moisture content to no more than 7wt% to give a dried bean intermediate; subjecting the dried bean intermediate to a particle size reduction step whereby no more than 2wt% of the product has a particle size of greater than or equal to 150µm characterized in that substantially no solids other than fat are removed; and a whole cocoa bean product is produced as the end product;
Patent ES-2297487-T3 (ES)
Inventor: FERRANTE JOSEPH
IPC: A61B17/78
Filed: 2004-09-08
Granted: 2008-05-01
Abstract: Systems, devices and methods are disclosed for treating fractures. The systems, devices and methods may include one or both of an implant, such as an intramedullary nail, and a fastening assembly, such as a lag screw and compression screw assembly. The implant in some embodiments has a proximal section with a transverse aperture and a cross-section that may be shaped to more accurately conform to the anatomical shape of cortical bone and to provide additional strength and robustness in its lateral portions, preferably without requiring significant additional material. The fastening assembly may be received to slide, in a controlled way, in the transverse aperture of the implant. In some embodiments, the engaging member and the compression device are configured so that the compression device interacts with a portion of the implant and a portion of the engaging member to enable controlled movement between the first and second bone fragments. This configuration is useful for, among other things, compressing a fracture.
Patent ES-2360222-T3 (ES)
Inventor: BOND SILAS
IPC: C07D487/04
Filed: 2004-12-24
Granted: 2011-06-02
Abstract: Compounds of formula I   
salts, and pharmaceutically acceptable derivatives thereof, wherein: A, together with the atoms to which it is attached, represents an optionally substituted phenyl ring; B-C is an optionally substituted link of the formula -CH 2 -(CH 2 ) z -, where z is 1-4; X and Y are independently selected from O, S and NR 6 , where R 6  is independently selected from hydrogen, C 1-6 alkyl, hydroxy and C 1-6 alkoxy; and R 1  and R 2 ;are as defined herein; are described. The compounds are useful as antiviral agents in particular the treatment of infections involving viruses of the  Pneumovirinae  subfamily.