baber/WOPTO huggingface dataset:
Patent WO-2021091871-A1 (WO)
Inventor: LU WUYUAN
IPC: A61K47/69
Filed: 2020-11-03
Abstract: L'invention concerne des antagonistes peptidiques de MDM2 et de MDMX. Les antagonistes peptidiques comprennent des antagonistes de MDM2 ou de MDMX, ainsi que des antagonistes à double spécificité selon lesquels le même peptide est un antagoniste de MDM2 et de MDMX à la fois. Les antagonistes peptidiques ont au moins une affinité de liaison nanomolaire pour MDM2 et/ou pour MDMX et, dans certains cas, une affinité de liaison picomolaire. Les antagonistes peptidiques peuvent être utilisés dans des méthodes basées sur un blocage d'inhibition de l'activité de p53 par MDM2 et/ou par MDMX. Ces méthodes peuvent être utilisées pour le traitement de maladies, telles que le cancer.
Patent WO-2021108310-A1 (WO)
Title: Verres à ténacité à la rupture élevée présentant une tension centrale élevée
Inventor: DEJNEKA MATTHEW
IPC: C03C3/095
Filed: 2020-11-23
Abstract: L'invention concerne un article à base de verre d'une composition comprenant : de 48 % en moles à 75 % en moles de SiO2; de 8 % en moles à 40 % en moles d'Al2O3; de 9 % en moles à 40 % en moles de Li2O; de 0 % en moles à 3,5 % en moles de Na2O; de 9 % en moles à 28 % en moles de R2O, dans laquelle R est un métal alcalin et R2O comprend au moins du Li2O et du Na2O; de 0 % en moles à 10 % en moles de TaO; de 0 % en moles à 4 % en moles de ZrO2; de 0 % en moles à 4 % en moles de TiO2; de 0 % en moles à 3,5 % en moles de R'O, R' étant un métal sélectionné parmi Ca, Mg, Sr, Ba, Zn et des combinaisons de ceux-ci; et de 0 % en moles à 8 % en moles de RE2O3, RE étant un métal des terres rares sélectionné parmi Sc, Y, La, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, et des combinaisons de ceux-ci. Le verre est à échange d'ions. R2O + R'O − Al2O3 − Ta2O5 + 1.5*RE2O3 − ZrO2 − TiO2 se situe dans une plage de ‑8 % en moles à 5 % en moles. ZrO2 + TiO2 + SnO2 se situe dans une plage de 0 % en moles ou plus à 2 % en moles ou moins. La composition est dépourvue d'As2O3, de Sb2O3, et de PbO.
Patent WO-2022139785-A1 (WO)
Inventor: FRIONA CLAIRE
IPC: A23B4/03
Filed: 2020-12-21
Abstract: A dehydrator including a first tray having a first surface, a first lip, and a first side wall extending between the first surface and the first lip. The first tray further includes a first ridge extending from the first surface, a first post extending from the first surface, a first hole formed in the first ridge, and a second hole formed in the first surface. The dehydrator further includes a second tray having a second surface, a second lip, and a second side wall extending between the second surface and the second lip. The second tray further includes a second ridge extending from the second surface, a second post extending from the second surface, a third hole formed in the second ridge, and a fourth hole formed in the second surface. A chamber is formed between the first tray and the second tray.
Patent WO-2021163158-A1 (WO)
Title: Conductor support structure position monitoring system
Inventor: KELLEY MICHAEL LEE
IPC: G01R31/00
Filed: 2021-02-10
Abstract: A sensor unit includes an orientation sensor, an electronic processor coupled to the orientation sensor, and memory coupled to the electronic processor and storing support structure configuration data and instructions. The instructions, when executed by the electronic processor, cause the sensor unit to monitor a position of a conductor support structure associated with the sensor unit based on data from the orientation sensor and generate an alert message responsive to determining that the position violates a position threshold. The position threshold is generated based on the support structure configuration data.
Patent WO-2021183464-A1 (WO)
Title: Personal care compositions
Inventor: LI MIN
IPC: A61Q5/02
Filed: 2021-03-09
Abstract: Described herein are personal care compositions comprising a complex comprising a plurality of short chain fatty acids; along with methods of making and using same.
Patent WO-2021183575-A1 (WO)
Title: Composite anti-fouling coatings and associated systems and methods
Inventor: SHORT MICHAEL
IPC: C09D5/16
Filed: 2021-03-09
Abstract: Composite anti-fouling coatings and associated systems and methods are generally described. In some aspects, a system comprises a substrate, a composite coating disposed on at least a portion of the substrate, and a fluid comprising one or more foulants, where the composite coating is configured to be in physical contact with the fluid during use. The composite coating may comprise a first region comprising a first material and a second region comprising a second material that is different from the first material. According to some embodiments, a full- spectral Hamaker constant associated with the composite coating and the fluid (i.e., based on average optical properties of the first and second materials of the composite coating) is relatively low, and the van der Waals (vdW) force between the composite coating and the one or more foulants is, therefore, correspondingly low. Under some conditions (e.g., high temperature and/or high pressure conditions), intermolecular interactions between the composite coating and the one or more foulants may be dominated by the vdW force, and a relatively low vdW force may reduce the likelihood of the one or more foulants adhering to and/or otherwise being deposited on the composite coating. By selecting materials for the composite coating that result in a relatively low full- spectral Hamaker constant, fouling of the composite coating may thus be reduced or even eliminated. In some cases, two or more materials with optical properties (e.g., refractive indices, frequency-dependent dielectric response values) that, when averaged, are substantially similar to those of the fluid across a spectrum of frequencies or wavelengths may advantageously be associated with a relatively low full- spectral Hamaker constant.
Patent WO-2021211228-A1 (WO)
Title: Clock domain translation for non-synchronized sensors
Inventor: MURPHY THOMAS
IPC: G01S5/06
Filed: 2021-03-10
Abstract: There is described an upstream device for translating clock domain for non-synchronized devices comprising a communication component (704), a memory component (708), and a processor (706). The communication component (704) detects a report received from a device that includes a beacon receive time in a device clock domain and a current report transmit time in the device clock domain. The memory component (708) provides a previous report receive time in the aggregator clock domain and a previous report transmit time in the device clock domain. The processor (706) identifies a current report receive time in an aggregator clock domain based on the report detected by the communication component. The processor (706) also determines a beacon receive time in the aggregator clock domain based, at least in part, on the beacon receive time in the device clock domain, the current report transmit time, the current report receive time, the previous report receive time, the previous report transmit time.
Patent WO-2021183812-A1 (WO)
Title: Modular grow boxes and associated systems and methods
Inventor: RAMIREZ ADAM
IPC: A01G31/02
Filed: 2021-03-11
Abstract: The present technology is generally directed to modular grow boxes for growing microgreens and other plants. The modular grow boxes generally include a first modular element having a plate and one or more walls extending therefrom to form a chamber, a second modular element having a platform for supporting a growth medium, and a third modular element that can act as a cover and/or base. The first, second, and third modular elements can be assembled in a first configuration that provides a generally enclosed area for growing plants during a germination phase. The first, second, and third modular elements can also be assembled in a second configuration that provides a partially exposed area for growing plants during a post-germination phase. In some embodiments, the modular grow boxes provide a self-contained, self-watering apparatus that is expected to simplify the process of growing microgreens and other plants.
Patent WO-2021194814-A1 (WO)
Title: Système et procédé de détermination d'un état de lubrifiant
Inventor: BLUMENFELD MICHAEL
IPC: G01N21/25
Filed: 2021-03-17
Abstract: L'invention concerne des systèmes et des procédés de détection de cuivre solubilisé dans des fluides lubrifiants. Dans un mode de réalisation, le système peut comprendre une enceinte dotée d'une ou plusieurs parties mobiles et ayant le fluide de lubrification disposé à l'intérieur de cette dernière ; un photodétecteur destiné à détecter une énergie lumineuse ; une source d'énergie permettant de générer et de projeter l'énergie lumineuse sur le photodétecteur, au moins une partie du fluide lubrifiant pouvant être disposée entre la source d'énergie et le photodétecteur ; un processeur ; une mémoire qui stocke des instructions qui peuvent amener le processeur : à recevoir un ou plusieurs signaux en provenance du photodétecteur, l'un ou plusieurs signaux pouvant être corrélés à une valeur d'énergie lumineuse de l'énergie lumineuse détectée par le photodétecteur ; et à comparer la valeur d'énergie lumineuse à une ou plusieurs valeurs d'énergie lumineuse stockées dans une table de consultation, les valeurs d'énergie lumineuse pouvant être corrélées à une quantité de cuivre solubilisé dans le fluide lubrifiant.
Patent WO-2021188851-A1 (WO)
Title: Antibodies against mucin 17 and uses thereof
Inventor: EDELMANN KURT
IPC: C07K16/30
Filed: 2021-03-19
Abstract: The present invention relates to antibodies that bind to human and monkey mucin 17 (MUC17). Moreover, the invention relates to a detection system comprising such antibodies. The antibodies or the detection system may be used for detecting or quantifying MUC17, for diagnosing a disease associated with MUC17, for patient stratification, monitoring disease progression, and evaluating the therapeutic response.
Patent WO-2021252047-A1 (WO)
Title: Semicrystalline poly(aryl ether ketone) copolymers
Inventor: WANG YIFENG
IPC: C08G8/02
Filed: 2021-03-25
Abstract: Compositions and methods for semicrystalline poly(aryl ether ketone) copolymers incorporating 2-benzimidazolinone and hydroquinone as comonomer units with 4,4'-dihalobenzophenone, and compositions and methods for semicrystalline poly(aryl ether ketone) copolymers incorporating 2-benzimidazolinone and hydroquinone as comonomer units with l,4-bis(4- dihalobenzoyl)benzene are described herein. The copolymers have advantageous properties, particularly in terms of their glass transition temperatures (Tg), crystallization temperatures from melt (Tc), melting temperatures (Tm), crystallinity and chemical resistance. The copolymers are suitable for manufacturing high temperature and chemical resistance molded systems and other articles of manufacture via injection molding, extrusion, compression molding, thermoforming and additive manufacturing.
Patent WO-2021202394-A1 (WO)
Title: Apparatus and method for convertible volume and pressure-controlled lung-protective ventilation
Inventor: MAGUIRE MICHAEL
IPC: A61M16/20
Filed: 2021-03-29
Abstract: A system for actuating a volume and/or pressure-controlled manual ventilator including a manual ventilator, a storage case, and an actuating mechanism. The manual ventilator includes a compressible body, an output one-way valve at an output end, and an input one way valve at an input end. The storage case includes an inner housing surface configured to accommodate the manual ventilator. The actuating mechanism includes a power unit mechanically coupled to a linear rod mechanism and one or more applicator pads mechanically coupled to the linear rod mechanism and proximal to the compressible body. The linear rod mechanism is configured to convert a rotating motion of the power unit into an axial movement of the linear rod mechanism. The actuating mechanism is configured to apply pressure to the compressible body of the manual ventilator via the one or more applicator pads such that a volume of the compressible body is deflated.
Patent WO-2021206950-A1 (WO)
Title: Ceramic additive manufacturing techniques for gas injectors
Inventor: HAZARIKA PANKAJ JYOTI
IPC: G03F7/20
Filed: 2021-03-29
Abstract: A ceramic gas injector and method of fabrication are described. The gas injector has an inlet portion to which a gas is introduced via an inlet hole and contains a conformal channel between the inlet hole and a sidewall, an outlet portion from which the gas is provided from the gas injector and a collar disposed between the inlet and outlet portions. The channel extends into the collar. The channel has channel sections each of which extends through the inlet portion and terminates at both inlet ends before reaching the inlet face and collar ends before reaching the outlet portion. Alternating adjacent pairs of channel sections are connected via the inlet ends with adjacent pairs that are not connected via the inlet ends connected via the collar ends. Ports in a sidewall of the collar are connected with an adjacent pairs of sections not connected via the inlet ends.
Patent WO-2021206992-A1 (WO)
Title: Method and apparatus for video coding
Inventor: LI GUICHUN
IPC: H04N19/176
Filed: 2021-04-01
Abstract: An apparatus for video decoding includes receiving circuitry and processing circuitry. In some examples, processing circuitry determines a parameter based on prediction information decoded from a coded video bitstream. The parameter is in a range that depends on a flag indicative of an enable/disable status of subblock based temporal motion vector prediction. Then, the processing circuitry calculates the maximum number of candidates in the subblock based merge candidate lists based on the parameter, and reconstructs, in response to a current block in a subblock based prediction mode, samples of the current block based on a candidate selection from a constructed subblock based merge candidate list of the current block. The constructed subblock based merge candidate list of the current block is constrained by the maximum number.
Patent WO-2021203066-A1 (WO)
Title: Filtration media
Inventor: JONES DEREK O
IPC: B01D39/08
Filed: 2021-04-02
Abstract: This disclosure describes a filtration medium that is preferably glass-free or substantially glass-free. In some embodiments, the filtration medium preferably exhibits capacity and efficiency comparable to or better than similar glass-containing filtration media. The filtration medium includes bicomponent fibers, efficiency fibers (for example, PET fibers), and microfibrillated fibers. The efficiency fibers include fibers having a fiber diameter in a range of 1 micron to 5 microns and fibers having a fiber diameter of at least 0.1 micron and less than 1 micron.
Patent WO-2021207049-A1 (WO)
Title: Inhalation formulations of 1'-cyano substituted carbanucleoside analogs
Inventor: ELLIS SCOTT
IPC: A61K9/08
Filed: 2021-04-05
Abstract: The present disclosure provides pharmaceutical formulations of the compound of Formula (I), Formula (la), or Formula (lb), or a pharmaceutically acceptable salt thereof, and an aqueous vehicle. The pharmaceutical formulations of the disclosure are useful in treatment and prevention of viral infections in subjects in need thereof and are for administration by inhalation.
Patent WO-2021236485-A1 (WO)
Title: Graphene-containing metalized silicon oxide composite materials
Inventor: HAYNER CARY MICHAEL
IPC: H01M10/052
Filed: 2021-05-17
Abstract: Active material composite particles, an electrode including the composite particles, a lithium ion secondary battery including the electrode, and method of forming the same, in which the composite particles each include a core particle including an alkali metal or an alkali earth metal silicate, and a coating disposed on the surface of the core particle. The coating includes turbostratic carbon having a Raman spectrum having: a D band having a peak intensity (ID) at wave number between 1330 cm -1  and 1360 cm-1; a G band having a peak intensity (IG) at wave number between 1580 cm- 1  and 1600 cm- 1 ; and a 2D band having a peak intensity (I2D) at wave number between 2650 cm -1  and 2750 cm- 1 , wherein a ratio of ID/IG ranges from greater than zero to about 1 .1,  and a ratio of I2D/IG ranges from about 0.4 to about 2.
Patent WO-2021236708-A1 (WO)
Title: Carrier with lid
Inventor: HOLLEY JOHN
IPC: B65D71/54
Filed: 2021-05-19
Abstract: A carrier for holding one or more products. The carrier can comprise a plurality of panels that extends at least partially around an interior of the carrier, the plurality of panels comprising at least a front panel and a side panel. A central panel can at least partially divide the interior of the carrier into a front portion and a back portion. The side panel can extend at least partially from the front panel to the central panel. A lid can at least partially close a top of the carrier
Patent WO-2021242909-A1 (WO)
Title: High throughput engineering of functional aav capsids
Inventor: VIGNEAULT FRANCOIS
IPC: C12N7/00
Filed: 2021-05-26
Abstract: Disclosed herein are engineered AAV VP capsid polypeptides with the ability to assemble into virus particles and having improved tissue tropism to, for example, CNS tissues. The capsids are engineered using the high throughput discovery system described herein. In certain embodiments, provided herein are recombinant adeno-associated virus (AAV) VP capsid polypeptides having at least one mutation in a residue corresponding to residue 581 to residue 589 in SEQ ID NO: 1.
Patent WO-2021252504-A1 (WO)
Title: Bowed plate for fixating osteotomies and joint arthrodeses
Inventor: TAYLOR ALAN
IPC: A61B17/58
Filed: 2021-06-08
Abstract: An apparatus and methods are provided for a bowed plate for fixating osteotomies and joint arthrodeses. The bowed plate includes a backplate comprising a support portion and an aperture portion that share an intervening central portion. The central portion angles the support portion and the aperture portion toward a midline of the bowed plate. A leg extends from the support portion and includes fixation features that enable the leg to grip an inner wall of a hole drilled in bone. A slanted aperture in the aperture portion is configured to countersink a bone screw. The central portion is configured to be straightened by way of a surgical bending instrument and implanted at a bone fixation or fusion site of a patient. Upon relaxing the surgical bending instrument, the leg and the bone screw compress the fusion site.
Patent WO-2021252693-A1 (WO)
Inventor: BURGESS TIMOTHY
IPC: G01V1/30
Filed: 2021-06-09
Abstract: Procédé de modélisation et de migration de données sismiques, qui consiste à utiliser une équation d'onde acoustique et une distribution spatiale d'un ou plusieurs paramètres de modèle terrestre. L'équation d'onde acoustique est modifiée en incluant au moins un terme source secondaire, et sur la base d'une configuration d'acquisition sismique, soit en calculant les signaux sismiques qui seraient détectés à partir du champ d'ondes modélisé soit en faisant migrer des signaux sismiques observés soit en faisant migrer des signaux résiduels en tant que partie d'une inversion.
Patent WO-2022026552-A1 (WO)
Title: Antiviral methods and compositions
Inventor: WHITTEN DAVID G
IPC: A61L2/08
Filed: 2021-07-28
Abstract: A method of inactivating an enveloped ssRNA virus, such as SARS-CoV-2. The method involves contacting the enveloped ssRNA virus with an antiviral polyelectrolyte compound and/or a conjugated aromatic compound effective to inactivate the virus. The disclosure also provides a method of reducing the period of viability of enveloped ssRNA virus, such as SARS-CoV-2, on personal protective equipment, in filtered air, and on surfaces that have come into contact with the virus.
Patent WO-2022035630-A1 (WO)
Title: Ultra-low-loss coupled-core multicore optical fibers
Inventor: BICKHAM SCOTT
IPC: G02B6/02
Filed: 2021-08-02
Abstract: A coupled-core multicore optical fiber has a plurality of cores that are doped with alkali metals or chlorine to achieve low attenuation and a large effective area. The cores may be embedded in a common cladding region that may be fluorine doped. The cores may also be doped with chlorine, either with the alkali metals described above or without the alkali metals.
Patent WO-2022035696-A1 (WO)
Title: Usim-calculated concealed identifier failure handling
Inventor: CHUANG PO-YING
IPC: H04W12/02
Filed: 2021-08-06
Abstract: In a mobile cellular network (100), a mobile network operator (MNO) or other entity can specify whether a user equipment (UE) (102) is to utilize either a concealed identifier (228, 230) (e.g., a subscription concealed identifier (SUCI)) calculated by a universal subscriber identity module (USIM) (222) of a universal integrated circuit card (UICC) (218) or a concealed identifier calculated by mobile equipment (ME) of the UE that is separate from the UICC and USIM. In the event that a USIM-calculated concealed identifier (230) is specified for use but the USIM fails in generation of a concealed identifier, the UE can utilize one or more failure recovery procedures (316, 318, 320) to attempt completion of attachment of the UE to the same network or a different network to help ensure that the UE does not remain attached to a network without access to services of the network due to authentication failure.
Patent WO-2022035934-A1 (WO)
Inventor: LI PANPAN
IPC: H01L29/88
Filed: 2021-08-11
Abstract: A method to fabricate micro-size III-nitride light emitting diodes (µLEDs) with an epitaxial tunnel junction comprised of a p+GaN layer, an In x Al y Ga z N insertion layer, and an n+GaN layer, grown using metalorganic chemical vapor deposition (MOCVD), wherein the µLEDs have a low forward voltage. The In x Al y Ga z N insertion layer has a smaller energy bandgap than the GaN layers, which reduces a depletion width of the tunnel junction and increases the tunneling probability. The µLEDs are fabricated with dimensions that vary from 25 to 10,000 µm 2 . It was found that the In x Al y Ga z N insertion layer can reduce the forward voltage at 20 A/cm 2  by at least 0.6 V. The tunnel junction µLEDs with an n-type and p-type In x Al y Ga z N insertion layer had a low forward voltage at 20A/cm 2  that was very stable. At dimensions smaller than 1600 µm 2 , the low forward voltage is less than 3.2 V.
Patent WO-2022035942-A1 (WO)
Title: Systems and methods for machine learning-based document classification
Inventor: SUNDARARAM SUDHIR
IPC: G06F16/583
Filed: 2021-08-11
Abstract: In some aspects, the disclosure is directed to methods and systems for machine learningbased document classification using multiple classifiers. Various classifiers may be employed during different iterations of the method to advance the classification of a document. The document may be classified and labeled in response to a predetermined number of classifiers agreeing upon a meaningful label. Further, the meaningful label may only be applied to the document in the event that the classifiers predicted the document label with a confidence score in excess of a threshold value.
Patent WO-2022060497-A1 (WO)
Inventor: ROBINSON MICHAEL LEE
IPC: F24F3/16
Filed: 2021-08-13
Abstract: A system for generating mist includes a vehicle with ventilation system, a misting device configured to atomized fluid to generate a variable amount of mist, and a fan configured to move the variable amount of mist through the ventilation system. The system further includes a particle sensor configured to measure particles and a controller in communication with the particle sensor, misting device, and fan, configured to receive a particle concentration from the particle sensor, compare it to a threshold, and control the variable amount of mist and/or the fan to keep the particle concentration greater than the threshold. A method for controlling mist in a vehicle includes pumping fluid to a misting device, generating a mist of fluid, pumping the mist into a vehicle ventilation system, measuring a particle concentration, and manipulating a misting device, pump, and/or fan using a controller to keep the particle concentration above a threshold.