baber/WOPTO huggingface dataset:
Patent NZ-256825-A (NZ)
Title: Ultrasonic nebuliser has a tube in the upper part of a holding chamber and an ultrasonic transducer
Inventor: CHEIMAN VLADIMIR
IPC: B05B17/06
Filed: 1993-10-15
Abstract: The device is designed for nebulizing liquids and for transporting the formed aerosols. It includes components to form a fountain of liquid that is being nebulized, a container holder (4), a container (2) with contact medium (3), an additional container (5) with liquid being nebulized (6), a nebulization chamber (7), a system for transporting the aerosol to the user, an outlet duct (11), and a mechanism for regulation of rate of delivery of aerosol. The nebulization chamber (7) is designed as a double-element structure, composed of an intake tube (8) and an expansion chamber (9). In the bottom of the expansion chamber (9) outlets (10) have been made for the drainage of the non-nebulized liquid back to the section of the container remote from the base of the fountain. This reduces the negative action of the non-nebulized liquid on the effectiveness of nebulization. The expansion chamber (9) which is incorporated into the nebulization chamber (7) ensures a significant reduction in coagulation of the aerosol particles, thus increasing the efficiency of the nebulizer and particle uniformity. The latter effect is likewise heightened by this specifically designed outlet duct (10) which accomplishes a process of gravitational filtration. As a consequence of the movement of the stream in the narrow intake tube (8) there is formation of a differential pressure, enabling transport of the aerosol from the nebulization chamber to the user. The above principles are proposed for application to multi-use and single-used devices.
Patent NZ-279265-A (NZ)
Title: Crystalline tripeptide derivative and medicaments
Inventor: PEGG STEPHEN JOHN
IPC: A61K/
Filed: 1995-02-07
Abstract: The present invention relates to pyrrolidine derivatives, and more particularly to the compound (S)-1-[(S)-2-(4-methoxybenzamido)-3-methylbutyryl]-N-[(S)-2-methyl-1-(trifluoroacetyl)propyl]pyrrolidine-2-carboxamide, shown by formula I, and solvates thereof. The present invention also provides pharmaceutical compositions, intermediates and methods of preparation of the compound. The compound of formula I is an inhibitor of human neutrophil elastase and is useful in the treatment of diseases in which the enzyme is implicated, such as, for example, emphysema and acute respiratory distress syndrome (ARDS).
Patent NZ-280327-A (NZ)
Title: Chilling semi-soft materials by contacting with cryogen: vapor removed from cryogen before it reaches chilling chamber
Inventor: APPOLONIA JOHN J
IPC: A23L3/375
Filed: 1995-10-25
Abstract: Apparatus and method for chilling soft solid or liquid materials in which liquid cryogen is more effectively dispersed to chill the materials and cryogenic vapour generated by the liquid cryogen is used to remove residual liquid cryogen from the apparatus and for other useful purposes including freezing the foodstuffs. The method comprises the following steps:   a) providing a quantity of soft or liquid material in a blender having a bottom such that the material forms a surface; b) providing a source of cryogen comprising liquid and vapour and separating said vapour from said liquid; c) injecting the separated liquid cryogen into the bottom of the blender at a level below the surface of any material therein; and d) mixing the soft solid or liquid material with the separated liquid cryogen.
Patent NZ-306664-A (NZ)
Title: Intermediates of camptothecin (CPT-11) or mappicine and their manufacture
Inventor: HENEGAR KEVIN E
IPC: C07D213/61
Filed: 1996-04-01
Abstract: Various intermediates as defined in the specification for preparing camptothecin derivatives, other compounds related to the synthesis of CPT-11 of formula (I) and compounds related to mappicine of formula (II) are claimed. The intermediates are based on 4-keto-pyridine, 2-pyridine-1,3-dioxolane, pyrano[3,4-c]pyridine, pyrano[3,4-c]indolizine or indolizine or on a compound of formula II. Also claimed are the processes for preparing the above compounds.
Patent NZ-314554-A (NZ)
Title: Arylthio, -sulphinyl and -sulphonyl pyrrole derivatives, and insecticidal compositions thereof
Inventor: BARNES KEITH DOUGLAS
IPC: C07D207/42
Filed: 1997-04-08
Abstract: There are provided arylthio, -sulfinyl and -sulfonyl pyrrole compounds having the structural formula I <CHEM>   Further provided are compositions and methods comprising those compounds for the control of insects.
Patent NZ-332637-A (NZ)
Title: Process for preparing 5,5-dimethyl-4-[(4-methylsulphonyl)phenyl]-2-(5H)-furanone derivatives which are useful as cox-2 inhibitors
Inventor: ROSSEN KAI
IPC: C07C319/20
Filed: 1997-05-27
Abstract: The process for preparing a 5,5-dimethyl-4-[(4-methylsulphonyl)phenyl]-2-(5H)-furanone derivative of formula I comprises: a)  reacting a thioanisole Me-S-phenyl in a non-reactive solvent and in the presence of a Lewis acid with isobutyryl chloride (Me)2CH-COCl to yield a compound of formula II; b) reacting the compound II with a brominating agent in a non-reactive solvent in the presence of a second solvent such as ethyl acetate to yield a compound of formula III; c) oxidising the compound III in a non-reactive solvent with an oxidising agent optionally in the presence of a suitable catalyst to yield a compound of formula IV; d) reacting the compound IV in an alkanol solvent with a compound of formula V HO-C(O)-CH2-O-R1 in the presence of a suitable base to yield a compound of formula VI; e) reacting the compound VI in an aprotic solvent with a strong base to yield a cyclized compound of formula VII which after dehydration in the presence of a water scavenger yields a compound of formula I. In the above formulae: R1 is alkyl or optionally substituted phenyl or naphthyl. The water scavenger can be isopropyl trifluoroacetate; the aprotic solvent can be acetonitrile and the strong base can be 1,8-diazabicyclo[5.4.0]undec-7-ene.
Patent NZ-333922-A (NZ)
Title: Controlled release device comprising a vapourised active, a polymer and a carrier.
Inventor: CATALDO DOMINIC C
IPC: A61K47/48
Filed: 1997-08-13
Abstract: A method of making a controlled release device is disclosed for controlling pests such as arachnids, millipedes, and crawling and boring insects.  The controlled release device has a polymer, a carrier, and an active chemical.  The active material is preferably, trifluralin. The method comprises the following steps: (a) blending the active chemical  with the carrier; (b) removing moisture from the carrier; (c) blending the active chemical with the dried carrier into a bound friable mixture; (d) adding the bound friable mixture into an amount of a polymer preform and forming a formable mixture; and (e) forming the formable mixture into the controlled release device. The polymer preform is preferably, a polymer powder of solithane.
Patent NZ-509364-A (NZ)
Title: Method and device for determining access to a subsurface target
Inventor: LANDI MICHAEL K
IPC: A61B6/08
Filed: 1999-06-15
Abstract: A targeting device defines a direction of approach to a subsurface target under guidance of imaging equipment such as a computer tomograph or a magnetic resonance imaging machine. The targeting device is positioned relative to the target in such a way that the optimal direction of approach avoiding vital internal structures can be selected by reference to the images displayed on the imaging equipment. The device projects a visible light beam, such as a laser beam, on a region of a patient, indicating the point of entry and the angle of approach to the subsurface target.
Patent NZ-510143-A (NZ)
Title: Apparatus for control and certification of the delivery of goods object of electronic commerce and for the concurrent control and certification of the execution of the related payment
Inventor: ARCIERI FRANCO
IPC: G06Q20/00
Filed: 1999-08-11
Abstract: An apparatus for control and certification of the delivery of goods object of electronic commerce and for the concurrent control and certification of the execution of the related payment includes a system for reading an electronic card and for managing authorization processes by the electronic card issuing company (26, 28, 30, 31), an apparatus (27) for monitoring and interpretation of application protocols for network data transmission systems connected to the system for reading an electronic card, and a data storing unit of the various transactions object of electronic commerce monitored and interpreted by means of the apparatus for monitoring and interpretation of the application protocols.
Patent NZ-510588-A (NZ)
Title: Pyrrolopyrimidines as protein kinase inhibitors
Inventor: HIRST GAVIN C
IPC: A61P15/00
Filed: 1999-09-17
Abstract: Pyrrolopyrimidines of formula (I) and their physiologically acceptable salts and metabolites that are inhibitors of serine/threonine and tyrosine kinase activity are disclosed. Several of the kinases, whose activity is inhibited by these pyrrolopyrimidine compounds, are involved in immunologic, hyperproliferative, or angiogenic processes. Thus, these chemical compounds can ameliorate disease states where angiogenesis or endothelial cell hyperproliferation is a factor. These compounds can be used to treat cancer and hyper proliferative disorders, rheumatoid arthritis, disorders of the immune system, transplant rejections and imflammatory disorders.
Patent NZ-511118-A (NZ)
Title: Activation of cellular immunity with antigenic proteins and hydrophobized polysaccharides, which have modified alkyl or cholesterol groups
Inventor: SHIKU HIROSHI
IPC: A61K39/00
Filed: 1999-09-30
Abstract: A cell with cellular immunity induced by reacting in vitro a complex comprising a hydrophobized polysaccharide, at a ratio of 0.5 to 5 per 100 saccharide units that constitute the polysaccharide, wherein the primary hydroxyl group is a group represented by the formula: -O-(CH2)mCONH(CH2)nNH-CO-O-R wherein R represents an alkyl group or a sterol residue; m represents 0 or 1; and n represents a positive integer; and an antigen with an antigen-presenting cell such as a dendritic cell.  The antigen-presenting cell has cellular immunity induced more efficiently than conventional vaccines.
Patent NZ-512250-A (NZ)
Title: Alkali-free, alkaline metal-free, and chloride-free setting and hardening accelerator for hydraulic binders
Inventor: SOMMER MARCEL
IPC: C04B24/12
Filed: 2001-06-08
Abstract: An alkali-free, alkaline meta-free and chloride-free setting and hardening accelerator for hydraulic binders comprising at least one water soluble fluoride comprising aluminum salt and at least one water soluble sulfate comprising aluminum salt. A method for the production of such an accelerator described herein, where the water soluble fluoride comprising aluminum salt is produced by combining an aluminum compound such as amorphous aluminum hydroxide, crystalline aluminum hydroxide, aluminum oxide or mixtures thereof with hydrofluoric acid, optionally at enhanced temperature, prior to the blending with other components and then optionally drying.
Patent NZ-513134-A (NZ)
Title: Device with a flexible shaft for removing bone grafts
Inventor: STEINER BEATRICE
IPC: A61M1/00
Filed: 2000-01-31
Abstract: The  invention relates to a device for  removing  bone grafts,  comprising a cutting tool (16) with a cutting  head (1),  a longitudinal shaft (8) attached to the cutting  head (1)  and  driving means (14) for the rotational movement  of the  cutting  tool (16), wherein the bone grafts  that  have been  cut by the cutting head (1) can be conveyed through  a continuos bore (10) in the cutting tool (16), the shaft  (8) is  elastically  mounted  on a part  (22)  attached  to  the cutting head (1) enabling torsion and/or bending around  the longitudinal  axis, the device can additionally  comprise  a vacuum  container  (17)  and  the  shaft  (8)  can  also  be attached  to  the container (17) during cutting and  removal of  bone  grafts by the end (21) which is distant  from  the cutting head (1).
Patent NZ-514426-A (NZ)
Title: An elastomeric backlit push button switch actuator
Inventor: BARRON PAUL
IPC: H01H13/14
Filed: 2001-09-25
Abstract: A switch actuating button which is formed from a pliant, light transmissive elastomeric material and shaped in a manner such that it may be held captive and project through an aperture of a mounting plate (80). The switch actuating button is coated with paint on a surface of the button that is projected through the mounting plate aperture and a window (60) is provided in the paint coating to permit emission of light from the rear of the actuating button. Indicia (90) is printed onto the paint coating and a clear gloss plastics material is applied to the whole of the surface that is projected through the aperture of the mounting plate (80).
Patent NZ-519544-A (NZ)
Title: Acid based micro-emulsions
Inventor: VON KROSIGK JAMES R
IPC: C09K23/00
Filed: 2000-12-05
Abstract: Acid based micro-emulsions are disclosed comprising water, an acid blend, an anionic surfactant, a nonionic surfactant, a co-solvent, a solvent and an oxidizer. The micro-emulsions have particular utility in cleaning oil sludges and drilling mud residues from well cuttings, well formations and down hole and surface oil well drilling and production equipment.
Patent NZ-520492-A (NZ)
Title: Whisk with wire loops covered with silicon tubing
Inventor: BROWNE PETER
IPC: A47J43/10
Filed: 2001-03-01
Abstract: A wire whisk that is safe for use on non-stick cookware with an array of flexible wire loops, each loop having two ends secured to the inner end of the handle.  The whisk has silicone tubing surrounding each wire loop to render it heat resistant but non-abrasive for use on non-stick coating surfaces.  The tubing and wire are secured relative to each other adjacent to the handle such that axial relative displacement is inhibited and rotational relative displacement is enabled while the tubing and wire are used with a food substance.  The wire loops and associated tubing may be disposed in any conventional whisk configuration such as that of a piano whisk; an egg whisk; a flat whisk; a balloon whisk; or a Swedish style/helical wire configuration.
Patent NZ-520829-A (NZ)
Title: Diphenylethylene compounds for treating diabetes and related conditions
Inventor: NAG BISHWAJIT
IPC: C07C43/23
Filed: 2001-02-05
Abstract: Diphenylethylene compounds that can be administered orally to decrease circulating concentrations of glucose are disclosed. These compounds are orally effective anti-diabetic agents that may normalize glucose and lipid metabolism in subjects with diabetes. The effect on insulin resistant rats is also shown. The effects on lipid and leptin concentrations are also shown.
Patent NZ-521709-A (NZ)
Title: Plant growing method and apparatus
Inventor: MINATO AKIHISA
IPC: A01G7/04
Filed: 2002-10-01
Abstract: A plant growing method comprising a step of supplying CO2, O2 or N2 in a pressurized state from one side separated with a permeable membrane that is permeable only to a gas and impermeable to a liquid while causing raw water to flow to an opposite side of the permeable membrane, a step of dissolving the CO2 , O2 or the N2 in the raw water so as to reach a predetermined concentration, and a step of intermittently atomizing resultant CO2, O2 or N2 dissolved water onto plants thereby promoting plant growth.
Patent NZ-528005-A (NZ)
Title: Biopesticide compositions containing antagonistic microorganisms and stimulating agents that have greater efficacy against diseases caused by pathogens to vegetal material
Inventor: JIJAKLI MOHAMED HAISSAM
IPC: A01N63/32
Filed: 2002-03-01
Abstract: Compositions suitable for use against one or more pathogens are described. The compositions comprise of at least one antagonistic micro-organism and at least one stimulating agent, which may be selected from the group consisting of one or more uronic acids, mannans and/or derivatives thereof and mixtures of those agents. A method for the biocontrol of disease caused by pathogens to vegetal material using the compositions of the invention is also described.
Patent NZ-529571-A (NZ)
Title: Human antibodies that bind human IL-12 and methods for producing
Inventor: SALFELD JOCHEN G
IPC: A61P19/08
Filed: 2000-03-24
Abstract: Disclosed is an isolated human antibody, or antigen-binding portion thereof, that binds to human IL-12 and dissociates from human IL-12 with a Kd of 1.31 x 10-10M or less and a koff rate constant of 1 x 10-3s-1 or less. Also disclosed is an isolated human antibody, or an antigen-binding portion thereof, which (a) inhibits phytohemagglutinin blast proliferation in an in vitro PHA assay with an IC50 of 1 x 10-9M or less, (b) has a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO:17, and (c) has a light chain CDR3 comprising the amino acid sequence of SEQ ID NO:18. Also disclosed is an isolated human antibody, or an antigen-binding portion thereof, having a heavy chain variable region comprising the amino acid sequence of SEQ ID NO:31, and a light chain variable region comprising the amino acid sequence of SEQ ID NO:32.
Patent NZ-529778-A (NZ)
Title: Cam drum switch to indicate wind turbine rotor pitch
Inventor: WOBBEN ALOYS
IPC: F03D80/70
Filed: 2002-04-24
Abstract: A cam-type switch to detect the pitch of the rotor blade of a wind turbine has an actuating shaft 16 rigidly connected to the rotor blade of the turbine to be rotated as the rotor blade pitch changes, and an actuator 19, 20 and a set of switches 22 disposed in a housing 10, 36. The actuator is in the form of a crank element with a first portion 19 connected to rotate with the shaft and a second arcuate portion 20 spaced from and coaxial with the shaft and including cam projections 23 which actuate the respective switches 22 as the cam rotates to indicate the rotor blade pitch angle.
Patent NZ-529947-A (NZ)
Title: A monitoring process and system
Inventor: DICKSON ADAM MATTHEW
IPC: G01P3/68
Filed: 2002-06-04
Abstract: A system for monitoring at least one moving object such as a vehicle includes: at least transmitter for transmitting optical signals modulated at respective modulation frequencies; at least one receiver adapted to detect at least one of the received optical signals on the basis of the modulation frequencies, and a means for detecting at least one of making and breaking of the at least one detected signals due to movement of the object to determine at least one parameter of the object. The receiver can include a sensor and an input circuit for converting at least one of the received optical signals to an electrical signal and an analog to digital converter for digitizing the electrical signal. The system can include a digital signal processor for demodulating the digitized signal from each of the receivers to provide output data representative of the at least one of making and breaking of the at least one of the detected optical signals.
Patent NZ-532097-A (NZ)
Title: Dosage forms having an inner core and outer shell
Inventor: BUNICK FRANK J
IPC: A61K9/14
Filed: 2002-09-28
Abstract: A dosage form comprises a core that has an outer core surface and a shell that has outer and inner surfaces. The shell surrounds the core so that the shell inner surface resides in substantially conformally upon the core outer surface. The shell thickness is in the range of about 100-400 microns and the relative standard deviation is less than 30%. The shell comprises less than 50% crytallizable sugar. The dosage form is substantially free of charge control agents and the shell is made by injecting a flowable material into a mold cavity.
Patent NZ-533802-A (NZ)
Title: Drinkable preparation comprising ketoprofen and the use thereof in the simultaneous treatment of a group of animals for processes which are accompanied by fever, inflammation and/or pain
Inventor: HOMEDES BEGUER JOSEP
IPC: A61K47/10
Filed: 2002-12-11
Abstract: Disclosed herein is a method of treating a respiratory disease in a herd of non-human animals comprising simultaneous oral administration of a drink preparation comprising an aqueous solution of ketoprofen and drinking water for animals or artificial milk for sucking animals, with an anti bacterial treatment.
Patent NZ-534168-A (NZ)
Title: Process for the preparation of high purity perindopril, an ACE inhibitor useful in treatment of cardiovascular diseases, and intermediates useful in the synthesis
Inventor: SIMIG GYULA
IPC: A61P43/00
Filed: 2003-01-29
Abstract: A process for the preparation of a compound of formula (I) and the t-butylamine salt of the formula (I') free of contaminations derivable from dicyclohexyl carbodiimide is disclosed, wherein the process comprises reacting the compound of formula (II) with a suitable carbonic acid derivative selected from alkyl chloroformate, benzyl chloroformate and di-alkyl-dicarbonate; activating the compound of formula (III) thus obtained (wherein R stands for lower alkyl or aryl-lower alkyl) with thionyl chloride; reacting the activated compound thus obtained with the compound of formula (IV) and if desired reacting the compound of formula (I) thus obtained with t-butylamine.
Patent NZ-538928-A (NZ)
Title: Administration form for pharmaceutically active peptides with sustained release of active ingredient, and method for the production thereof
Inventor: BAUER HORST
IPC: A61K9/06
Filed: 2003-09-26
Abstract: Disclosed is a pharmaceutical gel preparation including at least one pharmaceutically active ionic peptide compound selected from the group consisting of cetrorelix, teverelix, abarelix, ganirelix, azaline B, antide, detirelix, ramorelix, degarelix, D-63153 or a pharmaceutically active salt or mixture thereof, mixed in a predetermined amount of the value Xoptimum (in mg of peptide per ml of the preparation) with an aqueous solution of an inorganic or acetic acid salt in a predetermined concentration of the value Yoptimum (in % weight/volume), and after the mixing the administration can take place immediately, or a standing time is observed, and wherein the value Xoptimum is selected by a test method A including the stages of administration of various amounts Xn (number of different amounts n, where n is at least 1) (in mg) of the peptide as a mixture with an isotonic aqueous solution of mannitol onto or to a test system and selection of the amount Xoptimum (in mg of peptide per ml of mixture) which provided in the experiment the most favourable blood plasma levels of the peptide in the test system in relation to Cmax (maximum blood plasma concentration) and tmax (time until Cmax is reached), and the concentration Yoptimum being selected by a test method B including the stages of administration of the amount Xoptimum (in mg of peptide per ml of mixture) of the peptide as a mixture with aqueous solutions which differ in the concentration Yn (number of different concentrations n, where n is at least 1) (in % weight/volume) onto or to a test system and selection of the concentration Yoptimum (in % weight/volume) was fixed as the concentration which in the experiment resulted in the highest value for the plasma concentration Cactive, where C < Cactive < 0 (C = lowest plasma concentration of the peptide at which the peptide still has an adequate pharmaceutical effect in the experiment); at the same time, the salt has an influence on the time tactive until the active concentration in the plasma is reached, where tactive > tmax.
Patent NZ-543430-A (NZ)
Title: Crystalline VAP-1 and uses thereof
Inventor: SALMINEN TIINA
IPC: C07K14/705
Filed: 2004-05-25
Abstract: A crystalline human vascular adhesion protein 1 (VAP-1) and uses thereof, where the said crystal is defined as a crystal of space group P6522 with two molecules in the asymmetric unit and with unit dimensions of a = b = 225.9 angstroms, c = 218.7 angstroms, a = b = 90 degrees, g = 120 degrees.