baber/WOPTO huggingface dataset:
Patent DE-69417925-D1 (DE)
Inventor: BAKSHI RAMAN
IPC: A61K31/47
Filed: 1994-10-31
Granted: 1999-05-20
Abstract: Compounds of formula (I) are inhibitors of 5 alpha -reductase and are useful alone or in combination with 5 alpha -reductase 1 and/or 2 inhibitors for the treatment of hyperandrogenic disorders such as acne vulgaris, seborrhea, female hirsutism, male pattern baldness, and benign prostatic hyperplasia.
Patent DE-69505128-D1 (DE)
Inventor: AUTHELIN JEAN-RENE
IPC: A61K31/335
Filed: 1995-07-07
Granted: 1998-11-05
Abstract: PCT No. PCT/FR95/00910 Sec. 371 Date Apr. 25, 1997 Sec. 102(e) Date Apr. 25, 1997 PCT Filed Jul. 7, 1995 PCT Pub. No. WO96/01815 PCT Pub. Date Jan. 25, 1996Process for the preparation of 4-acetoxy-2 alpha -benzoyloxy-5 beta ,20-epoxy-1,7 beta , 10 beta -trihydroxy-9-oxo-tax-11-en-13 alpha -yl (2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate trihydrate, characterized in that the 4-acetoxy-2 alpha -benzoyloxy-5 beta ,20-epoxy-1,7 beta ,10 beta -trihydroxy-9-oxo-tax-11-en-13 alpha -yl (2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate is crystallized from a mixture of water and an aliphatic alcohol containing 1 to 3 carbon atoms, and then the product obtained is dried under defined conditions of temperature, pressure and humidity.
Patent DE-69519283-D1 (DE)
Inventor: PESCHER YVETTE
IPC: C02F1/78
Filed: 1995-02-01
Granted: 2000-12-07
Abstract: PCT No. PCT/FR95/00113 Sec. 371 Date Oct. 14, 1997 Sec. 102(e) Date Oct. 14, 1997 PCT Filed Feb. 1, 1995 PCT Pub. No. WO95/21136 PCT Pub. Date Aug. 10, 1995The present invention relates to a process for the purification of a medium containing organic waste. The process according to the present invention is characterized in that the starting medium (or effluent) containing the organic waste is subjected to the following stages: (i) treatment with at least one oxidizing agent; (ii) treatment with at least one flocculating agent; (iii) treatment with at least one polyelectrolyte, and in that the effluent obtained on conclusion of all of these stages is subjected to a filtration stage (iv), whereby a filtration cake and a filtrate are obtained. The process according to the present invention is more particularly useful for the treatment of pig manure.
Patent DE-69612126-D1 (DE)
Inventor: SWITALSKI STEVEN C
IPC: G01N33/52
Filed: 1996-01-30
Granted: 2001-04-26
Abstract: The test element includes a support, and a constant light-path providing layer consisting essentially of a diffusely-reflecting material that is sufficiently porous in all directions as to allow a liquid to spread uniformly in all directions, and homogeneously and diffusively reflects at least 95% of near infrared (NIR) radiation. The element is free of reagents capable of reacting with the analyte, and a hydrophilic polymer layer that is both separate from the light-path providing layer, and has a thickness equal to or greater than 1 micron. The element further includes a mirror layer in-between the light-path providing layer and the support and in contact with the support. Such arrangement is effective to increase the path length of NIR radiation through the layer.
Patent DE-69616480-D1 (DE)
Inventor: CARRUTHERS I
IPC: C07D211/74
Filed: 1996-06-04
Granted: 2001-12-06
Abstract: The invention relates to compounds of the formula R3, and U are as described herein. The compounds of the invention are NK1 or NK2 or NK3 receptor antagonists and as such are useful in the treatment of diseases such as asthma.
Patent DE-69622555-D1 (DE)
Inventor: FAHIM E
IPC: A61K39/116
Filed: 1996-05-02
Granted: 2002-08-29
Abstract: Vaccine for protecting humans against Bordetella pertussis infection comprises pertussis toxoid (I), filamentous haemagglutinin (II), pertactin (III) and agglutinogens (IV) of B. pertussis in relative amts. able to confer protection to >= 70% of an at-risk population. A single dose is 5-30 mu g (I) and (II), 3-15 mu g (III) and 1-10 mu g (IV), all expressed as nitrogen contents, esp. 10 mu g (I) and 5 mu g (II) or 20 mu g each of these, plus 5 mu g (III) and 3 mu g (IV). Vaccines are administered by subcutaneous or intramuscular injection. (IV) comprises fimbrial agglutinogens (Agg) 2 and 3 (pref. at ratio 1.5-2:1) but is free of Agg 1. These may also include diphtheria toxoid, pref. at 15 Lfs, and tetanus toxoid, pref. at 5 Lf, opt. also other non-Bordetella antigens. They can also include an adjuvant, specifically alum.
Patent DE-69627149-D1 (DE)
Inventor: MICHON FRANCIS
IPC: C07K/
Filed: 1996-06-06
Granted: 2003-05-08
Abstract: The process for depolymerizing Group B Types II and III Streptococcal Polysaccharide is disclosed which results in polysaccharide fragments having a reducing end suitable for conjugating to protein. Conjugate molecules, vaccines and their use to immunize mammals including humans are also disclosed.
Patent DE-69631779-D1 (DE)
Inventor: NILSSON CHRISTER
IPC: A61M25/00
Filed: 1996-10-09
Granted: 2004-04-08
Abstract: PCT No. PCT/SE96/01280 Sec. 371 Date May 6, 1998 Sec. 102(e) Date May 6, 1998 PCT Filed Oct. 9, 1996 PCT Pub. No. WO97/13543 PCT Pub. Date Apr. 17, 1997Catheters are disclosed for insertion into a body cavity. The catheters include a region near the distal end of the catheter which includes a number of apertures as well as a reduced diameter portion which has a diameter less than the diameter of the rest of the catheter region so that the flow of a fluid through the reduced diameter portion is reduced thereby.
Patent DE-69633289-D1 (DE)
Inventor: OHKAWA SHIGENORI
IPC: C07D215/227
Filed: 1996-06-26
Granted: 2004-10-07
Abstract: PCT No. PCT/JP96/01759 Sec. 371 Date Dec. 10, 1996 Sec. 102(e) Date Dec. 10, 1996 PCT Filed Jun. 26, 1996 PCT Pub. No. WO97/01539 PCT Pub. Date Jan. 16, 1997A compound of the formula:   <IMAGE>   wherein R1 represents hydrogen or an optionally substituted hydrocarbon group; R2 represents an optionally substituted hydrocarbon group, an optionally substituted amino group or a substituted hydroxyl group; X represents an optionally halogenated lower alkylene group; Y represents a substituent; n represents an integer of 0 to 6; and m represents 0 or 1; or a salt thereof, a process for producing it, an intermediate for the production, and a pharmaceutical composition containing it are provided.
Patent DE-69637140-D1 (DE)
Inventor: NG JOHN S
IPC: A61K31/58
Filed: 1996-12-11
Granted: 2007-08-02
Abstract: Multiple novel reaction schemes, novel process steps and novel intermediates are provided for the synthesis of epoxymexrenone and other compounds of Formula I wherein: -A-A- represents the group -CHR<SUP>4</SUP>-CHR<SUP>5</SUP>- or CR<SUP>4</SUP>-CR<SUP>5</SUP>- R<SUP>3</SUP>, R<SUP>4 </SUP>and R<SUP>5 </SUP>are independently selected from the group consisting of hydrogen, halo, hydroxy, lower alkyl, lower alkoxy, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, cyano, aryloxy, R<SUP>1 </SUP>represents an alpha-oriented lower alkoxycarbonyl or hydroxyalkyl radical, -B-B- represents the group -CHR<SUP>6</SUP>-CHR<SUP>7</SUP>- or an alpha- or beta-oriented group: where R<SUP>6 </SUP>and R<SUP>7 </SUP>are independently selected from the group consisting of hydrogen, halo, lower alkoxy, acyl, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, alkyl, alkoxycarbonyl, acyloxyalkyl, cyano, aryloxy, and R<SUP>8 </SUP>and R<SUP>9 </SUP>are independently selected from the group consisting of hydrogen, halo, lower alkoxy, acyl, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, alkyl, alkoxycarbonyl, acyloxyalkyl, cyano, aryloxy, or R<SUP>8 </SUP>and R<SUP>9 </SUP>together comprise a carbocyclic or heterocyclic ring structure, or R<SUP>8 </SUP>or R<SUP>9 </SUP>together with R<SUP>6 </SUP>or R<SUP>7 </SUP>comprise a carbocyclic or heterocyclic ring structure fused to the pentacyclic D ring.
Patent DE-69703444-D1 (DE)
Inventor: HOEG ANDREAS
IPC: F02B75/02
Filed: 1997-06-03
Granted: 2000-12-07
Abstract: An exhaust valve for an internal combustion engine including a movable spindle with a valve disc of a nickel-based alloy which also constitutes an annular seat area at the upper surface of the valve disc. The seat area abuts a corresponding seat area on a stationary valve member in the closed position of the valve. At manufacturing, the seat area of the valve disc is subjected to a thermo-mechanical deformation process at a temperature lower than or around the recrystallization temperature of the alloy. The seat area on the upper surface of the valve disc has been given dent mark preventing properties in the form of a yield strength of at least 1000 MPa at a temperature of approximately 20° C. by means of the thermo-mechanical deformation process and possibly a yield strength increasing heat treatment.
Patent DE-69706059-D1 (DE)
Inventor: BONNET HENRI
IPC: B65G47/94
Filed: 1997-10-15
Granted: 2001-09-13
Abstract: The Invention relates to an apparatus and a method for sorting objects into destination containers arranged along one or both sides of a continuous conveyer belt apparatus wherein appropriate portions of the belt can be raised and lowered at times and locations to cause objects to fall into appropriate destination containers. Air may optionally be directed toward said objects in coordination with the elevation of the belt to assist in causing the objects to fall into the appropriate destination container.
Patent DE-69716505-D1 (DE)
Inventor: LEITAO EUGENIA RIBEIRO DE SOUS
IPC: A61F2/00
Filed: 1997-05-12
Granted: 2002-11-28
Abstract: The invention provides a nanotechnology process for implant surface treatment for producing an implant article. The nanotechnology process comprises subjecting a non-porous material to a mechanical or chemical surface treatment until a surface roughness with an average peak distance (Ra value) between 10 and 1,000 nm is obtained. The roughened surface can subsequently be subjected to precipitation of calcium phosphate from a solution containing calcium and phosphate ions.
Patent DE-69727915-D1 (DE)
Inventor: YAMAZAKI KAZUO
IPC: C07D405/14
Filed: 1997-09-22
Granted: 2004-04-08
Abstract: The present invention relates to a substituted vinylpyridine derivative represented by the following formula (1): <CHEM> (wherein R<1> represents a hydrogen atom, an alkyl group, etc., R<2> represents an alkyl group; one of R<3> and R<4>, which are different from each other, represents a hydrogen atom and the other represents a nitrile group, R<5> represents an aryl group or a heteroaryl group, X represents an oxygen atom, etc., and one of Q<1>, Q<2>, and Q<3> represents a nitrogen atom and the other two represent CH); a salt of the derivative; and a drug containing the derivative or salt as the active ingredient. Due to strong PDE inhibitory action and TNF- alpha production inhibitory action, the derivative, salt, and drug are useful for the prevention and treatment of a wide variety of inflammatory diseases and autoimmune diseases.
Patent DE-69728671-D1 (DE)
Inventor: MORRIS M
IPC: B01D29/03
Filed: 1997-08-20
Granted: 2004-05-19
Abstract: A reticulated ceramic filter for molten metal has an inlet portion with an inlet surface, an intermediate body portion contiguous with the inlet portion and an outlet portion with an outlet surface. The inlet surface is non-planar with upper surfaces and lower surfaces to provide a substantial contact area for molten metal supplied to the inlet surface.
Patent DE-69731563-D1 (DE)
Inventor: FLEISCHER WOLFGANG
IPC: A61M11/00
Filed: 1997-12-23
Granted: 2004-12-16
Abstract: The particle separator (110) for separating large particles of an inhalable active-particle/carrier gas flow is provided with a housing (112) having an inlet opening (114) and an outlet opening (116). Further, the particle separator (110) comprises a plurality of partition walls (120-130) arranged behind each other between the inlet opening (114) and the outlet opening (116) in the housing (112). Each partition wall (120-130) comprises at least one opening (121-131), wherein the openings (121-131) of adjacent partition walls (120-130) are arranged in a mutually displaced relationship and the partition walls (120-130) are arranged at inclined positions to the longitudinal direction of the particle separator (110).
Patent DE-69738580-D1 (DE)
Inventor: MAHONEY RALENE S
IPC: G01K1/14
Filed: 1997-05-30
Granted: 2008-04-30
Abstract: A fluid pressure and temperature sensing probe assembly for a mass flow measurement system comprising, a tubular body, a portion of which is adapted for insertion into the fluid flowing in a confined conduit, and having, within the body, a pair of separated plenums. Openings are provided in the tubular body which expose the respective plenums to high and low fluid pressures in the fluid flow. An electrically responsive temperature sensor, having an electrical signal output, is disposed within the tubular body of the probe. A pressure transducer, in fluid communication with the plenums, converts the fluid pressures in the plenums to at least one electrical signal representative of the difference between the high and low fluid pressures. A transmitter transmits the electrical signal from the pressure transducer and the electrical temperature signal to a remote location.
Patent DE-69739801-D1 (DE)
Inventor: BEN-HAIM SHLOMO
IPC: A61B17/00
Filed: 1997-07-09
Granted: 2010-04-22
Abstract: An apparatus comprises circuitry for creating a non-excitor electric potential between at least two points located in the vicinity of a muscle. A method is provided which employs the apparatus for reducing the contraction force of a muscle.
Patent DE-69801380-D1 (DE)
Inventor: FOGLINO ROBERTO
IPC: B65H3/44
Filed: 1998-01-02
Granted: 2001-09-27
Abstract: A device (21) for selectively feeding sheets (24, 28) contained in two separate trays (22, 26) by means of a pick-up unit (31), wherein the latter is located between the two trays (22,26). The latter-named (22, 26) are fulcrum-mounted on a structure (33) and are driven alternatively by a motor (61) depending on the latter's direction of rotation so as to be brought selectively into sliding engagement with the pick-up unit (31), and accordingly result in one sheet at a time being picked up and fed from one or the other of the two trays (22, 26). The device (21) is particularly suitable for incorporation in an office machine, such as for example a facsimile system (20) or a printer, for selectively feeding sheets of different types. <IMAGE>
Patent DE-69802610-D1 (DE)
Inventor: NIELSEN CHRISTIAN OELLEGAARD
IPC: B23Q7/14
Filed: 1998-04-30
Granted: 2002-01-10
Abstract: An apparatus (54) for moving items in a working machine and comprising a housing with mutual parallel front and back walls, between which turning means (58) for a transport member (30) with carrier means (12, 36) are arranged, which preferably via an opening (10) in the back wall (6) are drive-connected with a linear guidance (38) displaceable in horizontal and vertical directions, having a number of projecting tools adapted for moving of items, and a servo motor (28) preferably mounted at the front wall, where said transport member consists of an endless roller chain (30), which is arranged around said turning means in form of a toothed wheel (58), a chain tightener mechanism (60, 62) and a driving wheel (64) connected with said servo motor (28), where said opening is formed by a guide slot (10) extending along the roller chain (30), and where said carrier means (12, 36) are such connected with the roller chain (30), that these are able to pass the turning means and transfer the rotation of the servo motor via said linear guidance to preferably combined linear movements of said tools. By means of simple provisions the apparatus may be produced so compact, that it can be mounted directly on the tool plane, and it becomes possible to obtain a precise and quick moving of items between a number of working stations. <IMAGE>   <IMAGE>   <IMAGE>
Patent DE-69804432-D1 (DE)
Inventor: NISHIO SHIGENORI
IPC: G05D7/06
Filed: 1998-12-16
Granted: 2002-05-02
Abstract: A flow control device which can variably control the flow rate with extremely high accuracy over a wide flow rate range from a high to a low flow rate with a single pump. A pump is provided in a main pipe line through which fluid is fed. A bypass branches from the main pipe line at a point nearer to the discharge port than is the pump. A flowmeter and a flow control valve are provided in the bypass. In the bypass is further provided a back pressure regulating valve near the discharge port. The degree of opening of the flow control valve is adjusted based on the flow rate detected by the flowmeter. The back pressure regulating valve suppresses pressure fluctuation on the discharge side of the flow control valve. <IMAGE>
Patent DE-69811090-D1 (DE)
Inventor: HOIUM A
IPC: G02B6/44
Filed: 1998-08-11
Granted: 2003-03-06
Abstract: A cable conveying apparatus and method installs a cable in conduit by the application of a pushing force generated by a drive assembly. The speed of the cable and the speed of the drive assembly are monitored wherein the drive assembly is shut off when the drive assembly and cable speeds exceed a predetermined difference. The cable conveying apparatus includes a blower, and a missile attached to the lead end of the cable, wherein the missile sealably and slideably engages the conduit such that the blower and missile combine to generate a pull force on the cable which cooperates with the pushing force of the drive assembly so as to install the cable in the conduit. The cable conveying apparatus also includes a high speed cable shut off system, and a low speed cable shut off system. The drive assembly includes two opposed continuous chains each including a plurality of cable engaging pads, and each driven by a hydraulic motor. A hydraulic cylinder preferably holds the drive chains at a spaced apart distance.
Patent DE-69817573-D1 (DE)
Inventor: SCHMIDT GARY
IPC: F24D3/10
Filed: 1998-06-16
Granted: 2003-10-02
Abstract: A water manifold is usable in the construction of a fluid-based heat-transfer system for space heating, the supply and distribution of potable water, and other applications. The water manifold is formed from a number of elements in a flexible manner, in that the elements are assembled as needed for a particular application. A plurality of manifold segments 100, each supporting a pipe directed away from a main pipe, transfer heat to a specific area, and may be be connected in a linear manner, as required by the design of the application. A cross tee segment 300 is attachable to the manifold segments, and may be used to support a thermometer unit 200, an automatic air vent or other apparatus. A spigot 400 is attachable to the cross tee segment, adjacent to the thermometer. An open end cap 500 provides a male plastic fitting connected to a brass female fitting, thereby allowing connection of the manifold to metal plumbing. A closed end cap 600 allows the manifold to be terminated. A support bracket 700 is adapted to connect to the manifold segments for support.
Patent DE-69827676-D1 (DE)
Inventor: WILSON A
IPC: B01D53/04
Filed: 1998-10-26
Granted: 2004-12-23
Abstract: An electrically regenerable gas filter system includes a carbon fiber composite molecular sieve (CFCMS) filter medium (7) for separation and purification, or catalytic processing of fluids. Filter medium (7) is made of carbon fibers rigidly bonded to form an open, permeable, rigid monolith capable of being formed to near-net-shape. A separate medium-efficiency pre-filter (5) removes particulate from a supply airstream before the airstream passes through the CFCMS filter (7) to sorb gaseous air polutants. The airstream is then recirculated to a space. When saturated, CFCMS media (7) is regenerated utilizing a low-voltage current from power supply (22) that is caused to pass through filter media (7).
Patent DE-69829570-D1 (DE)
Inventor: KABANOV V
IPC: A61K47/34
Filed: 1998-06-11
Granted: 2005-05-04
Abstract: A composition for facilitating delivery of biological agents, comprising a supramolecular complex including as constituents a block copolymer, having at least one nonionic, water soluble segment and at least one polyionic segment, and at least one charged surfactant having hydrophobic groups, the charge of the surfactant being opposite to that of the polyionic segment of the block copolymer. The constituents of the complex are bound by interaction between the opposite charges thereof and between surfactant hydrophobic groups. The complex may include an anionic surfactant having a biological activity, in which case the net charge of such anionic surfactant is no more than about 10.
Patent DE-69835598-D1 (DE)
Inventor: PIENIAK A
IPC: A61F13/15
Filed: 1998-04-30
Granted: 2006-09-28
Abstract: A disposable absorbent article, which can be configured as a disposable diaper, a panty-type garment, or an adult incontinent product, includes a backsheet, an absorbent panel positioned on top of the backsheet, and a liquid permeable topsheet positioned on top of the absorbent panel. A pair of longitudinally extending, elasticized unitary leg gather assemblies are positioned on respective opposite sides of a longitudinal centerline of the article. Each leg gather assembly includes an outer sleeve having an upstanding portion within which are positioned at least two, and preferably at least three, elastically contractible elastic elements which effect conformance of the leg gather assemblies with a wearer for desired containment. A lowermost one of the elastic elements in each leg gather assembly exerts a relatively greater elastic gathering force than the other elastic elements to effect gathering of associated components of the article, thus enhancing fit. Apart from the leg gather assemblies, side marginal portions of the absorbent article are non-elasticized for enhanced aesthetics, and for facilitating efficient, high-speed manufacture.
Patent DE-69836087-D1 (DE)
Inventor: GROOMS M
IPC: A61F2/46
Filed: 1998-08-27
Granted: 2006-11-16
Abstract: The present invention relates to at least one implant (100) consisting substantially of cortical bone, said implant comprising a canal surrounded by a continuous or discontinuous wall of cortical bone in the shape of a circle, an ellipse, or an asymmetrical shape, thereby forming an implant having a top face and a bottom face, either of which is substantially planar, with said planes being substantially parallel to each other.
Patent DE-69837475-D1 (DE)
Inventor: BLINKOVSKY ALEXANDER
IPC: A23L27/21
Filed: 1998-05-15
Granted: 2007-05-16
Abstract: The present invention relates to isolated polypeptides having aminopeptidase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
Patent DE-69903371-D1 (DE)
Inventor: MAITRE JEAN-LOUIS
IPC: C11D17/00
Filed: 1999-05-12
Granted: 2002-11-14
Abstract: A detergent tablet with a sandwich structure of at least three layers comprises: (1) two external layers comprising an antiscaling agent; and (2) an internal layer comprising a bleaching agent. The external layers dissolve faster than the internal layer and are retarding agents for the internal layer in order to pretreat the washing water against lime scale. The tablet dissolves in two steps: first the external layers, then the internal layer when the external layers are entirely dissolved. An Independent claim is also included for the manufacturing of the tablet.