baber/WOPTO huggingface dataset:
Patent CA-3152554-A1 (CA)
Inventor: ROSTAMI-HODJEGAN AMIN
IPC: C12Q1/6881
Filed: 2020-09-23
Abstract: An assay method is provided for determining the status of the health of a tissue within the body of a subject, wherein the tissue comprises an abundance of at least a first target protein, wherein assay comprises analysis of a liquid biopsy sample obtained from the subject, and wherein the liquid biopsy sample comprises at least a first cell free mRNA (cf-mRNA) that encodes the at least a first target protein. The assays and methods are useful in the diagnosis and treatment of liver health in a subject. In particular, methods and systems are provided for the diagnosis and treatment of fatty liver; non-alcoholic steatohepatitis (NASH); cirrhosis; liver disease; hepatitis; and liver cancer.
Patent CA-3153043-A1 (CA)
Title: Systemes, procedes et appareils de disposition et d'echange de plateaux
Inventor: MILLER ADAM QUINN
IPC: B65G65/23
Filed: 2020-09-03
Abstract: L'invention concerne un dispositif de manutention de plateaux destiné à transporter un plateau dans ou hors d'une position sélectionnable au sein d'un empilement de plateaux rangé dans le dispositif de manutention de plateaux qui comprend une station de déchargement pour ranger un plateau pendant une opération de tri, un releveur de plateaux conçu pour transporter verticalement l'empilement de plateaux jusqu'à la position sélectionnable de sorte que le plateau soit positionné pour être reçu horizontalement à partir ou par la station de déchargement, et un séparateur au-dessus du releveur de plateaux et accouplé à la station de déchargement, le séparateur étant conçu pour diviser verticalement l'empilement de plateaux afin d'ouvrir la position sélectionnable et de transporter horizontalement le plateau dans ou hors de la station de déchargement.
Patent CA-3155800-A1 (CA)
Inventor: BERSANI MARCO
IPC: C02F1/02
Filed: 2020-10-29
Abstract: An apparatus (10) for treating wastewater (30), for the recovery of metals contained therein. The apparatus (10) comprises: - a first pump (11), - a second pump (12), - heating means (13), of which the input is connected to the first pump (11) and the output to a mixer (14), - the mixer (14), of which a first input is connected to the heating means (13), a second input to the second pump (12), and an output to cooling means (15), - the input of the cooling means (15) being connected to the mixer (14) and the output to depressurization means (16), - the input of the depressurization means (16) being connected to the cooling means (15) and the output to liquid/solid separation means (17), - the input of the liquid/solid separation means (17) being connected to the depressurization means (16).
Patent CA-3157635-A1 (CA)
Title: Isolation tool and methods of isolating a section of pipe or a vessel
Inventor: NABER DAVID
IPC: F16L55/12
Filed: 2021-11-08
Abstract: The present disclosure provides an isolation tool for isolating a section of pipe or a vessel and rnethods for isolating a section of a pipe or a vessel. In particular, the present disclosure provides a double isolation and bleed (DI B) isolation tool, for use in line-stopping operations and rnethods of line isolation ernploying the isolation tool.
Patent CA-3158147-A1 (CA)
Inventor: GREEN ALON
IPC: B61L7/00
Filed: 2020-12-10
Abstract: A system and method of supervising vehicle positioning of a vehicle along a guideway where the vehicle comprising a supervisory controller, at least two controllers communicatively connected with the supervisory controller, an inertial measurement unit (IMU) and a speed measurement sensor includes receiving, by the controllers, speed measurements from the speed measurement sensor and motion measurements from the inertial measurement unit. The two controllers each estimate the along-track position of the vehicle using a track constrained UKF function based on the received speed measurements and motion measurements. The system executes protection level and protection level supervision functions on the supervisory controller to validate the along-track position estimates. The protection level supervision function uses a Stanford diagram verification technique.
Patent CA-3159896-A1 (CA)
Inventor: TURK MICHAEL F
IPC: G21K5/04
Filed: 2020-11-24
Abstract: The present invention relates to linear, straight through electron beam machines that incorporate a rotary coupling system to easily attach and manually or automatically rotate field defining members such as applicators and/or shields to the electron beam machines. The rotary coupling systems also incorporate functionality for using different kinds of optical signals to automatically provide illumination, reference mark projection, and/or distance detection. The optical signals generated downstream from heavy collimator components and are transmitted along the central axis of the field defining elements so that function and accuracy are maintained as the components rotate.
Patent CA-3163581-A1 (CA)
Inventor: ROBAS NICOLA
IPC: A61K45/06
Filed: 2021-01-22
Abstract: La présente invention concerne des compositions pharmaceutiques, telles que des compositions pharmaceutiques topiques, comprenant certains composés imidazo[1,2-b]pyridazine et des sels et/ou solvates de qualité pharmaceutique de ceux-ci . L'invention concerne également des procédés de préparation des composés, et les utilisations de telles compositions dans le traitement de maladies ou d'affections associées à l'activité de la kinase liée à la tropomyosine (Trk). Plus spécifiquement, l'invention concerne des compositions pharmaceutiques topiques comprenant un composé de formule (I) ou des sels pharmaceutiquement et/ou des solvates de qualité pharmaceutique de celui-ci, qui sont utiles dans l'inhibition de Trk.
Patent CA-3165324-A1 (CA)
Inventor: MULLER-HAGEDORN MATTHIAS
IPC: B01J19/24
Filed: 2022-06-23
Abstract: An apparatus (100,200, 500) comprising at least one burner (106, 208, 300) having a plurality of co-axial channels and a Control System (502) for regulating a length of a flame (102, 206) for partial oxidation of hydrocarbon feed in a reactor (104, 202, 508) is provided. The at least one burner (106, 208, 300) comprises a first channel (108, 210, 302) to inject a stream of oxidizer, a second channel (110, 212, 304) to inject a stream of the hydrocarbon feed and a third channel (112, 214, 306) to inject a stream of swirl gas at a first velocity into the hydrocarbon feed stream. The Control System (502) regulates the length of the flame (102, 206) to have a constant flame shape and position by regulating the first velocity of the swirl gas that generates the swirl motion within the hydrocarbon feed stream.
Patent CA-3165891-A1 (CA)
Title: Agent prophylactique et/ou therapeutique pour le syndrome de la douleur pelvienne chronique/prostatique chronique
Inventor: OKAMOTO KEN
IPC: A61K31/4184
Filed: 2020-12-24
Abstract: La présente invention concerne un agent prophylactique et/ou thérapeutique pour le syndrome de la douleur pelvienne chronique/prostatique chronique, ledit agent comprenant un inhibiteur de mPGES-1 comme ingrédient actif.
Patent CA-3166418-A1 (CA)
Title: Compensation de lectures manquantes a partir d'un dispositif de surveillance de glucose dans un systeme de distribution d'insuline automatise
Inventor: ZHENG YIBIN
IPC: A61M5/172
Filed: 2021-02-11
Abstract: Certains modes de réalisation donnés à titre d'exemple permettent de résoudre le problème de lectures manquantes de concentration de glucose sanguin à partir d'un dispositif de surveillance de glucose qui transmet des lectures de concentration de glucose sanguin sur une connexion sans fil, dues à des problèmes avec la connexion sans fil. Selon les modes de réalisation donnés à titre d'exemple, un dispositif de distribution d'insuline automatisée (AID) utilise une estimation à la place d'une lecture manquante de concentration de glucose sanguin pour la détermination d'une future lecture de concentration de glucose sanguin prédite pour un utilisateur. Le dispositif AID peut ainsi fonctionner normalement dans la génération de réglages de distribution d'insuline en dépit de la non-réception d'une lecture de concentration de glucose sanguin courante d'un cycle courant. Il n'est pas nécessaire de suspendre la distribution d'insuline à l'utilisateur en raison de la lecture manquante de concentration de glucose sanguin.
Patent CA-3168568-A1 (CA)
Title: Vibratory conveyor for bulk material
Inventor: SCHULTHEIS WINFRIED
IPC: B65G27/04
Filed: 2022-07-22
Abstract: A vibratory conveyor for bulk material comprises a conveying trough or tube, at least one vibration generator configured to generate a directed vibratory excitation for transporting the bulk material in longitudinal direction through the conveying trough or tube, and at least one retaining weir for decelerating movement of the bulk material. The weir has a front wall pointing opposite to a direction of transport and a rear wall pointing in direction of transport. The length of the front wall in longitudinal direction of the conveying trough or tube from the runout at bottom side to an apex of the weir is smaller than the length of the rear wall in longitudinal direction of the conveying trough or tube from said apex to the runout at bottom side.
Patent CA-3170128-A1 (CA)
Inventor: JOSEPH SEAN
IPC: C07K16/22
Filed: 2021-02-11
Abstract: Disclosed herein are granulocyte-macrophage colony-stimulating factor (GM-CSF) peptides and compositions comprising GM-CSF peptides. These molecules may be useful for the treatment of neurological diseases or conditions.
Patent CA-3171544-A1 (CA)
Inventor: KAMISHITA TAIZOU
IPC: A61P31/16
Filed: 2021-03-22
Abstract: L'invention concerne un procédé de production d'anticorps IgA trimériques et tétramériques, le procédé comprenant le mélange d'anticorps IgA dimériques et d'anticorps IgA monomériques.
Patent CA-3171709-A1 (CA)
Title: T-cell bispecific binding proteins
Inventor: PALCHAUDHURI RAHUL
IPC: C07K16/28
Filed: 2021-03-16
Abstract: Provided herein are compositions and methods useful for the T-cell mediated depletion of hematopoietic stelm cells (HSCs) expressing an HSC antigen, e.g., CD117+ cells, and for the treatment of various hematopoietic diseases, metabolic disorders, cancers, e.g., acute myeloid leukemia (AML) and autoimmune diseases, among others. Described herein are bispecific binding polypeptides, and bispecific antigen-binding portions thereof, comprising a first binding moiety to a T cell antigen, such as CD3, and a second binding moiety to an HSC antigen, such as CD117.
Patent CA-3174587-A1 (CA)
Inventor: LEE JAU-NAN
IPC: C12N5/073
Filed: 2021-05-04
Abstract: Des cellules souches pluripotentes mortelles produites in vitro à partir de cellules souches extra-embryonnaires telles que des cellules souches trophoblastiques, des compositions correspondantes et des utilisations correspondantes sont divulguées. Des procédés de culture des cellules souches pluripotentes mortelles produites in vitro avec un ou plusieurs agents inducteurs pour produire une population cellulaire sont également divulgués. Des méthodes de traitement d'un trouble ou d'une pathologie à l'aide des cellules divulguées dans la description ou de cellules qui en sont différentiées sont également divulguées.
Patent CA-3175545-A1 (CA)
Title: Dispositifs de reparation de valve cardiaque et dispositifs de distribution associes
Inventor: OBERWISE ERIC MICHAEL
IPC: A61F2/24
Filed: 2021-12-17
Abstract: La présente invention concerne un dispositif implantable ou un implant configuré pour être positionné à l'intérieur d'une valve cardiaque native pour permettre à la valve cardiaque native de former un joint plus efficace. Dans certains modes de réalisation, le dispositif implantable ou implant, ou une ou plusieurs portions de celui-ci, peut être configuré pour se dilater et/ou se contracter. Par exemple, le dispositif implantable ou l'implant peut rétrécir pendant la distribution et se dilater lors de l'implantation sur la valve cardiaque native.
Patent CA-3178469-A1 (CA)
Title: Universal access layer for accessing heterogeneous data stores
Inventor: YANG KEVIN
IPC: G06F7/00
Filed: 2021-04-02
Abstract: Methods and systems disclosed herein describe a universal access layer that allows a plurality of applications to obtain data and/or information from a plurality of heterogeneous data stores. The universal access layer may include one or more application data objects to validate requests, transform a format of the request, determine which data stores comprise the requested data and/or information, encrypt the request, combine responses into a single response, and retransform the response prior to sending it to the requesting application. By using the universal access layer, applications may improve the speed with which they access data and/or information from the plurality of heterogeneous data stores.
Patent CA-3178542-A1 (CA)
Inventor: LOZANO-DUBERNARD BERNARDO
IPC: A61P31/14
Filed: 2021-02-22
Abstract: Described is a recombinant vaccine, active or inactivated, against COVID-19, which comprises a Newcastle's disease viral vector and a pharmaceutically acceptable vehicle, adjuvant and/or excipient, the vaccine being characterised in that the viral vector is a virus capable of generating a cellular immune response and has an inserted exogenic SARS-CoV-2 nucleotide sequence.
Patent CA-3179564-A1 (CA)
Title: Compositions et procedes pour la carboxymethylation de la cytosine d'adn
Inventor: KOHLI RAHUL
IPC: C12Q1/48
Filed: 2021-05-19
Abstract: L'invention concerne des compositions et des procédés de carboxyméthylation de l'ADN contenant de la cytosine et leurs applications pour le séquençage direct de 5 mC.
Patent CA-3179898-A1 (CA)
Title: Matrice de separation et procede de separation
Inventor: MALOISEL JEAN-LUC
IPC: B01D15/38
Filed: 2021-04-16
Abstract: L'invention concerne une matrice de séparation comprenant une pluralité de ligands multimodaux couplés de manière covalente à un support, ledit support étant une membrane comprenant des fibres polymères non tissées et lesdits ligands étant capables d'interagir avec une biomacromolécule cible. En outre, l'invention concerne des procédés de séparation utilisant la matrice de séparation.
Patent CA-3180324-A1 (CA)
Title: Flexible headrest for ophthalmic instrument
Inventor: BONAVENTURA RUSSELL J
IPC: A42B3/12
Filed: 2021-05-05
Abstract: A headrest for an ophthalmic instrument facilitates fine positioning of the instrument relative to an eye of a test subject without the need to remove a contact element of the headrest from contact with the test subject's face. The ophthalmic instrument may be, for example, a rebound tonometer or a non-contact tonometer. The headrest includes a hollow bulbous contact element formed of resiliently deformable material, for example a thermoplastic elastomer (TPE) or silicone rubber. An outer surface of the contact element may have a spherical shape or a spheroidal shape when the contact element is not deformed.
Patent CA-3181535-A1 (CA)
Title: Methods for the use of a b7-h3 antibody-drug conjugate alone or in combination
Inventor: BOHAC GERRY CHESTER
IPC: C07K16/28
Filed: 2021-05-10
Abstract: The present invention is directed to dosing regimens for administering a humanized anti- B7-H3 antibody conjugated to at least one duocarmycin moiety (a "B7-H3-ADC") for the treatment of cancer, particularly a cancer associated with expression of B7-H3. The invention particularly concerns the use of such B7-H3-ADC optionally in combination with a PD-1 binding molecule for the treatment of cancer. The invention particularly concerns the use of such B7-H3-ADC and an anti-PD-1 antibody or a PD-1 X LAG-3 bispecific molecule. The invention is directed to the use of such molecules, and to the use of pharmaceutical compositions and pharmaceutical kits that contain such molecules and that facilitate the use of such dosing regimens in the treatment of cancer.
Patent CA-3181609-A1 (CA)
Inventor: EL KHOURY VICTORIA
IPC: G01N33/574
Filed: 2021-04-28
Abstract: Sont divulgués dans la présente demande des méthodes vitro de diagnostic du cancer du poumon chez un sujet, la méthode consistant à détecter au moins un biomarqueur choisi dans le groupe constitué par l'inhibiteur de dissociation Rho GDP bêta (ARHGDIB), l'alpha-tubuline 4A (TUBA4A), le glutathion S-transférase oméga 1 (GSTO1), la filamine A (FLNA), la peroxyrédoxine 6 (PRDX6) et la cadhérine 13 (CDH13) dans un échantillon biologique provenant du sujet, ainsi que des kits permettant de mesurer ledit au moins un biomarqueur.
Patent CA-3182446-A1 (CA)
Title: Systems and methods for classifying a webpage or a webpage element
Inventor: MUELLER ERIK
IPC: G06F16/95
Filed: 2022-11-18
Abstract: Disclosed are methods and systems for classifying a webpage or one or more webpage elements. For instance, a method include detecting, by a user device, that a user of the user device has navigated to the webpage using a web browser installed on the user device and classifying, by the user device, the webpage or the one or more webpage elements into a classification by inputting first input data into one or more machine learning models. The method may further include, in response to classifying the webpage or the one or more webpage elements into the classification, causing the user device to display a user interface associated with an electronic application. The user interface may include information identifying the classification of the webpage.
Patent CA-3182779-A1 (CA)
Title: Script de programmation pour le traitement d'images et son application dans un procede de determination d'images faciologiques
Inventor: DE SOUZA FIORITI LENITA
IPC: E21B47/002
Filed: 2021-06-15
Abstract: La présente invention concerne un script de programmation destiné à extraire des contrastes de contours dans des images, de manière à faciliter le procédé de détermination d'images faciologiques. L'invention propose un outil pour faire ressortir l'hétérogénéité des roches pour l'identification de normes texturales et structurales typiques, en lien avec des faciès sédimentaires. Elle fait intervenir l'algorithme « Canny Edge Detection » et des paramétrages dans un environnement de langage de programmation Python, dans le but d'extraire les contrastes de contours observés sur des profils des images capturées des roches. D'autres résultats obtenus au moyen de l'invention sont la suppression d'artéfacts, la superposition d'images et la quantification des contrastes de bords. Ces résultats ont été incorporés dans un procédé de détermination d'images faciologiques. Par ailleurs, l'utilisation des produits générés dans des modèles de prédiction d'électrofaciès, de productivité et de corrélation entre puits est prometteuse. Ainsi, le script mis au point fournit des informations importantes pour l'industrie du pétrole.
Patent CA-3183247-A1 (CA)
Inventor: SMYTH CATHAL
Filed: 2022-12-05
Abstract: Methods, systems, and techniques for detecting a cybersecurity breach. The cybersecurity breach may be a synthetic account or an account having been subjected to an account takeover. Electronic account data representative of accounts is obtained in which a first group of the accounts includes accounts flagged as being associated with the breach, and a second group of the accounts includes a remainder of the accounts. The computer system generates from the account data nodes representing the accounts and edges based on account metadata that connect the nodes. The computer system determines, such as by applying a link analysis method to the nodes and edges, a ranking of the accounts of at least part of the second group indicative of a likelihood that those accounts are also associated with the cybersecurity breach. That ranking may be used to identify which of those accounts is also identified with the cybersecurity breach.
Patent CA-3189137-A1 (CA)
Title: Methods and compositions for stimulating gamma delta t cells
Inventor: COPIK ALICJA
IPC: A61K35/17
Filed: 2021-08-12
Abstract: Compositions and methods for stimulating ?? T cell expansion and cytotoxicity are described. Therapeutic compositions and methods using expanded and stimulated ?? T cells are described.
Patent CA-3189425-A1 (CA)
Inventor: GUROVICH NIKOLAY
IPC: A61F2/24
Filed: 2021-07-26
Abstract: An implantable prosthetic device can include a frame movable between a radially compressed configuration and a radially expanded configuration, and a valvular structure. The frame can have an inflow orifice, an outflow orifice, and one or more commissure windows. The valvular structure can include a plurality of leaflets, each leaflet having a main body with an inflow edge, an outflow edge, and a pair of opposing tabs. Each tab can be paired with an adjacent tab of an adjacent leaflet to form a commissure tab assembly, and each commissure tab assembly being coupled to a respective commissure window. Each tab can extend from the main body at an angle such that a radially outer edge of the tab corresponds to a draft angle of the frame.
Patent CA-3191715-A1 (CA)
Title: Functional safety in autonomous driving
Inventor: NEHMADI YOUVAL
IPC: B60W60/00
Filed: 2020-09-22
Abstract: Autonomous driving of a vehicle in which computerized perception by the vehicle, including of its environment and of itself (e.g., its egomotion), is used to autonomously drive the vehicle and, additionally, can also be used to provide feedback to enhance performance, safety, and/or other attributes of autonomous driving of the vehicle (e.g., when certain conditions affecting the vehicle are determined to exist by detecting patterns in or otherwise analyzing what is perceived by the vehicle), such as by adjusting autonomous driving of the vehicle, conveying messages regarding the vehicle, and/or performing other actions concerning the vehicle.
Patent CA-3194027-A1 (CA)
Inventor: DOGAN MEESHANTHINI V
IPC: C12Q1/6883
Filed: 2021-09-03
Abstract: Ce document décrit des méthodes et des compositions visant à prédire et/ou à surveiller le diabète. Spécifiquement, ce document décrit des méthodes et des compositions destinées à déterminer l'état de méthylation d'au moins un locus CpG et d'au moins un polymorphisme mononucléotidique (SNP).
Patent CA-3195253-A1 (CA)
Title: Dry foam comprising agar-agar
Inventor: VIDAL VINCENT
IPC: A61L31/18
Filed: 2021-09-20
Abstract: The present invention relates to a dry foam comprising agar-agar characterized by an elasticity modulus from 0.02 to 0.6 MPa, particularly from 0.15 to 0.6 MPa, more particularly from 0.3 to 0.4 MPa, a manufacturing process thereof and the uses thereof in particular as an embolization agent.
Patent CA-3195685-A1 (CA)
Inventor: SUNDAL BJORN MAGNE
IPC: G01T1/20
Filed: 2021-09-21
Abstract: Capteur de radon qui comprend : une chambre de diffusion ; une photodiode positionnée à l'intérieur de la chambre de diffusion ; et un photomultiplicateur positionné à l'intérieur de la chambre de diffusion, un matériau scintillant étant disposé sur au moins une partie d'une surface interne de la chambre de diffusion. Cet agencement reconnaît que les deux capteurs fournissent des informations différentes. En particulier, le photomultiplicateur détecte davantage de particules alpha, mais ne peut pas distinguer les énergies de différentes particules alpha. D'autre part, la photodiode peut distinguer différentes désintégrations parce que l'amplitude du signal généré par la photodiode est proportionnelle à l'énergie cinétique de la particule alpha qui la heurte. En d'autres termes, la photodiode produit des données spectrales (un spectre d'énergie). Les données spectrales peuvent être utilisées pour estimer la quantité de polonium qui adhère aux aérosols et donne donc une indication du niveau d'aérosols dans la chambre. Ceci peut être utilisé pour appliquer un facteur de correction aux données pour donner une meilleure estimation de la concentration de radon réelle dans la chambre. Ceci peut être combiné aux données de comptage du photomultiplicateur pour obtenir des données globales améliorées.